Axsun OCT Swept Laser and System

Axsun OCT Swept Laser
and System
Seungbum Woo, Applications Engineer
Karen Scammell, Global Sales Director
Bill Ahern,
Director of Marketing
Photonix Japan, April. 2011
Photonix Japan 2011
Outline
1. Optical Coherence Tomography (OCT)
2. Axsun Company and Swept Laser Technology Overview
3. Axsun Swept Laser Performance
4. Axsun Swept Laser Engine Products
5. OCT Imaging using Axsun OCT Swept Lasers
6. Conclusion
Photonix Japan
2011
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Optical Coherence Tomography
OCT Techniques
1. Time-domain OCT
2. Frequency-domain OCT
• Spectral-domain OCT
• Swept-source OCT
Swept-Source OCT advantages
– Enables balanced and polarization diverse detection schemes
– Longer Wavelengths, such as 1060 and 1300 nm, enable deeper
penetration into tissue
– Increased imaging depth range from slower signal roll-off
– High SNR and Resolution in a compact, rugged package
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Axsun Company and
Laser Technology
Overview
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Axsun Technologies Inc.
AXSUN MODULE ASSEMBLY FACILITY
•
A wholly owned subsidiary of Volcano
Corporation (Nasdaq: VOLC)
•
Founded in 1998, located in Billerica, MA,
USA
•
Shipping over ten thousand optical engines
annually into Telecom, Industrial
Spectroscopy and Medical Imaging
applications
•
Unique tunable MEMS and optical integration
technology
•
~125 employees
•
104 Issued Patents
Optical Engine
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High Precision Optical Assembly
Unique Devices
Optical Bench
Optical Engine
Module
Complete Subsystem
•
Automated pick & place for mounting components
•
Axsun Micro-Robot achieves 50nm precise active alignment
•
25 Year Reliability
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Axsun MEMs External Cavity
Tunable Laser
Tunable FP
Filter
Lens Gain Lens
Fiber
Reflector
Output
Optical
Fiber
SOA
Laser Cavity
14 mm
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Micro-Electro-Mechanical System
(MEMS) Tunable Filters
MEMS Fabry-Perot Filter Structure
Wafer Scale Processing
Si
HR Coated
Flat Mirror
Optical Cavity
HR Coated Curved
Mirror on Tethered
Membrane
Electrode Gap
V
Filter Assembly
Tethered
Membrane
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Micro-Optical Bench Packaging
Platform
MEMS tunable filter
Si micro lens
LIGA alignment structure
Output Fiber pigtail
Micro-optical bench
y
x
z
SOA gain chip
Microlens
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f
fiber
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Functional Integration: Co-Packaged
K-Clock
Tunable
Filter
Laser
Output
Fiber
Detector
Etalon
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Axsun Swept Laser
Performance
Photonix Japan 2011
Axsun Laser Tuning Range (Bandwidth)
BW > 100 nm
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BW > 110 nm
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6
Signal FFT (dB=20*log10)
Axsun Laser Coherence Length
5
0
-5
-10
-15
-20
-25
-30
-35
-40
-45
-50
-55
-60
0
Coherence Length = 13.5 mm
Operating conditions:
2
4
6
8
10
12
14
16
18
20
22
– l ~ 1060 nm
– 110 nm tuning
range
– 100 kHz scan
rate
Full Length (mm)
 Coherence length Lc = 13.5 mm
 Corresponds to 55 pm dynamic laser linewidth FWHM for a Gaussian lineshape
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Axsun Laser RIN data
 RIN < -120 dBc/Hz from 10-90MHz
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Axsun Swept Laser
Engine Products
Photonix Japan 2011
OCT system with Axsun SS Laser + Axsun DAQ
Clock
DAQ Board
Signal
Clock interferometer
Sweep
Trigger
Swept Laser
10
90
Probe
20
80
Balanced
Receiver
50
50
Variable Delay
1060 nm OCT “Engine”
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Axsun OCT products
Axsun Camera Link DAQ Board
Axsun Swept Laser OEM Engine
Axsun Swept Laser Benchtop Engine
Axsun Swept Laser Engine with
integrated DAQ
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Axsun OCT Laser Specifications
1310 Swept
Source
Output Power
(Average) (mW)
1060 Swept
Source
18
15
1250-1360
980 – 1100
nm
Sweep Rate (kHz)
50
100
Coherence Length
(Round Trip PL, mm)
13
10
K-Clock Depth (Std, mm)
lTuning Range (nm)
5
3.7
K-Clock Frequency
(MHz)
130
330
Balanced Detector
Optional
Optional
105
102
Demonstrated Sensitivity
* (dB)
Power Supply (vDC)
Size (OEM, mm)
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2011
+12
+12
114 x 177 x 58
114 x 177 x 58
Highlights:
•
High output power (15-18 mW with
back trace blanking)
•
> 100 nm tuning range (for imaging
resolution < 8 µm @1060nm or 15
µm @1310nm
•
> 10 mm long coherence length =
imaging depth > 5 mm
•
50–100 kHz scan rates for fast
data acquisition
•
Compact, reliable, and designed
for volume manufacturing
•
Low noise (RIN < 120dBc/Hz)
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OCT System Performance with
Axsun SS Engine and DAQ
Sensitivity for 2.5 mW sample power
120
100
80
Noise
Signal
SNR
SNR + Loss
60
Operating conditions:
40
dB
– l ~ 1060 nm
– 110 nm tuning
range
– 100 kHz scan rate
20
0
-20
 Shot Noise Limited
sensitivity of 102dB.
-40
-60
0.001
0.01
0.1
1
10
100
1000
10000
Reference Power (uW)
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SNR over Imaging Depth
 Slow SNR rolloff enables
longer imaging depth
range
1060 47kHz
InGaAs Camera
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850nm 91kHz
CMOS Camera
Axsun 1060nm
100kHz Engine
Ref:
Benjamin Potsaid, Bernhard
Baumann, David Huang,
Scott Barry, Alex E. Cable,
Joel S. Schuman, Jay S.
Duker, and James G.
Fujimoto, "Ultrahigh speed
1050nm swept source /
Fourier domain OCT retinal
and anterior segment
imaging at 100,000 to
400,000 axial scans per
second," Opt. Express 18,
20029-20048 (2010)
20
10
Image Resolution over Image Depth
Resolution for Hann window
Resolution (microns)
25
20 dB
20
15
10 dB
10
3 dB
Resolution at 3,
10 and 20 dB
points
5
0
0
1
2
3
Depth (mm)
 Transform limited resolution thorough entire imaging
depth
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Axsun DAQ Board
Features
•
1 channel 500MS/s
•
12-bit Resolution
•
Supports a wide range of laser
sweep rates
•
200MHz Bandwidth (configurable)
•
Number of points per A Scan
configurable
•
Configurable with external k-clock
or internal 500MSPS clock
•
A-line trigger output via SMA
connector
•
Base Camera Link® interface
configuration
•
85MHz, 24 bit Pixel Data
•
USB interface
Provides an easy Swept Laser Upgrade
path to camera based OCT systems
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OCT Imaging with the
Axsun Swept Laser
Engine
Photonix Japan 2011
OCT Images of Teeth at 1310 nm
5 mm
3D OCT image of a tooth
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2011
Cross sectional OCT image of a tooth
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OCT Images of Anterior Segment
at 1310 nm
Images courtesy of Nicolaus Copernicus University, Torun, Poland
OCT image of
an eye after
corneal
transplantation
OCT image of anterior
eye chamber after
corneal transplantation
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Retinal Image with 1060nm Axsun
Swept Laser Engine
Choroid
Sclera
Image taken at Rotterdam Ophthalmic Institute, Rotterdam, Netherlands
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Retinal/AS Images with 1060nm Axsun
Swept Laser Engine
Images Generated by Massachusetts Institute of Technology
RLE 1
Ultrahigh speed 1050nm swept source / Fourier domain OCT retinal and anterior segment imaging at 100,000 to
400,000 axial scans per second 13 September 2010 / Vol. 18, No. 19 / OPTICS EXPRESS 20029
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Axsun Images 1060nm 100kHz
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World Class Retinal Imaging
Image Courtesy of
Topcon
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Conclusions
• Axsun has developed a novel Tunable laser for sweptsource optical coherence tomography (OCT)
– Meets or exceeds all requirements for SSOCT Systems
• Axsun has developed control, clock and data acquisition
electronics to offer a compact Ultra High Speed OCT
Imaging System
– Interfaces with commercial Camera Link frame grabbers
• Excellent optical performance and OCT imaging
• Axsun swept laser based optical engines are enabling a
range of OCT applications in cardiology, dentistry,
ophthalmology, endoscopy and other applications
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Thank you.
Please visit us at the Systems Engineering
Booth
Photonix Japan
2011
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