TOC - Journal of the American Heart Association
Transcription
TOC - Journal of the American Heart Association
JAHA: Journal of the American Heart Association Volume 5, Issue 6 June 2016 Editorials Meta-Analysis of Medication Adherence Interventions Among Heart Failure Patients: The Lumpers Make Their Case Prateeti Khazanie and Larry A. Allen e003827 doi: 10.1161/JAHA.116.003827 It Happened While You Were Sleeping Downloaded from http://jaha.ahajournals.org/ by guest on November 20, 2016 L. Kristin Newby e003748 doi: 10.1161/JAHA.116.003748 Intravenous Hydration and Contrast-Induced Acute Kidney Injury: Too Much of a Good Thing? Rajesh Gupta, Ankush Moza, and Christopher J. Cooper e003777 doi: 10.1161/JAHA.116.003777 Original Research Arrhythmia and Electrophysiology Dysfunction of the Voltage-Gated K+ Channel β2 Subunit in a Familial Case of Brugada Syndrome Vincent Portero, Solena Le Scouarnec, Zeineb Es-Salah-Lamoureux, Sophie Burel, Jean-Baptiste Gourraud, Stéphanie Bonnaud, Pierre Lindenbaum, Floriane Simonet, Jade Violleau, Estelle Baron, Eléonore Moreau, Carol Scott, Stéphanie Chatel, Gildas Loussouarn, Thomas O’Hara, Philippe Mabo, Christian Dina, Hervé Le Marec, Jean-Jacques Schott, Vincent Probst, Isabelle Baró, Céline Marionneau, Flavien Charpentier, and Richard Redon e003122 doi: 10.1161/JAHA.115.003122 Atrioventricular Node Slow-Pathway Ablation Reduces Atrial Fibrillation Inducibility: A Neuronal Mechanism Xiaomeng Yin, Yutao Xi, Shulong Zhang, Yunlong Xia, Lianjun Gao, Jinqiu Liu, Nancy Cheng, Qi Chen, Jie Cheng, and Yanzong Yang e003083 doi: 10.1161/JAHA.115.003083 Fetal Atrial Flutter: Electrophysiology and Associations With Rhythms Involving an Accessory Pathway Annette Wacker-Gussmann, Janette F. Strasburger, Sharda Srinivasan, Bettina F. Cuneo, William Lutter, and Ronald T. Wakai e003673 doi: 10.1161/JAHA.116.003673 Cardiovascular Nursing Medication Adherence Interventions Improve Heart Failure Mortality and Readmission Rates: Systematic Review and Meta-Analysis of Controlled Trials Todd M. Ruppar, Pamela S. Cooper, David R. Mehr, Janet M. Delgado, and Jacqueline M. Dunbar-Jacob e002606 doi: 10.1161/JAHA.115.002606 Cardiovascular Surgery Intima–Media Thickness Is Linearly and Continuously Associated With Systolic Blood Pressure in a Population-Based Cohort (STANISLAS Cohort Study) João Pedro Ferreira, Nicolas Girerd, Erwan Bozec, Jean Loup Machu, Jean-Marc Boivin, Gérard M. London, Faiez Zannad, and Patrick Rossignol e003529 doi: 10.1161/JAHA.116.003529 Congenital Heart Disease Long-Term Survival of Individuals Born With Congenital Heart Disease: A Systematic Review and Meta-Analysis Katie E. Best and Judith Rankin e002846 doi: 10.1161/JAHA.115.002846 Coronary Heart Disease Severe Obesity Is Associated With Increased Risk of Early Complications and Extended Length of Stay Following Coronary Artery Bypass Grafting Surgery Tasuku Terada, Jeffrey A. Johnson, Colleen Norris, Raj Padwal, Weiyu Qiu, Arya M. Sharma, Wonita Janzen, and Mary Forhan e003282 doi: 10.1161/JAHA.116.003282 Athens QRS Score as a Predictor of Coronary Artery Disease in Patients With Chest Pain and Normal Exercise Stress Test Raza Alvi, Eduard Sklyar, Robert Gorski, Moustapha Atoui, Maryam Afshar, and Jonathan N. Bella e002832 doi: 10.1161/JAHA.115.002832 Intestinal Microbiota-Generated Metabolite Trimethylamine-N-Oxide and 5-Year Mortality Risk in Stable Coronary Artery Disease: The Contributory Role of Intestinal Microbiota in a COURAGE-Like Patient Cohort Downloaded from http://jaha.ahajournals.org/ by guest on November 20, 2016 Vichai Senthong, Zeneng Wang, Xinmin S. Li, Yiying Fan, Yuping Wu, W. H. Wilson Tang, and Stanley L. Hazen e002816 doi: 10.1161/JAHA.115.002816 Variation in Practice Regarding Pretreatment With Dual Antiplatelet Therapy for Patients With Non–ST Elevation Myocardial Infarction Ali Shafiq, Javier Valle, Jae-Sik Jang, Mohammed Qintar, Kensey Gosch, David J. Cohen, Mandeep Singh, Richard Bach, and John A. Spertus e003576 doi: 10.1161/JAHA.116.003576 Relationship Between Low-Density Lipoprotein Cholesterol, Free Proprotein Convertase Subtilisin/Kexin Type 9, and Alirocumab Levels After Different Lipid-Lowering Strategies Jacques Rey, Franck Poitiers, Tobias Paehler, Aurélie Brunet, A. Thomas DiCioccio, Christopher P. Cannon, Howard K. Surks, Jean-Louis Pinquier, Corinne Hanotin, and William J. Sasiela e003323 doi: 10.1161/JAHA.116.003323 Circulating Levels of IL-6 Receptor and gp130 and Long-Term Clinical Outcomes in ST-Elevation Myocardial Infarction Vibeke N. Ritschel, Ingebjørg Seljeflot, Harald Arnesen, Sigrun Halvorsen, Jan Eritsland, Morten W. Fagerland, and Geir Ø. Andersen e003014 doi: 10.1161/JAHA.115.003014 Change in Angina Symptom Status After Acute Myocardial Infarction and Its Association With Readmission Risk: An Analysis of the Translational Research Investigating Underlying Disparities in Acute Myocardial Infarction Patients’ Health Status (TRIUMPH) Registry Jacob A. Doll, Fengming Tang, Sharon Cresci, P. Michael Ho, Thomas M. Maddox, John A. Spertus, and Tracy Y. Wang e003205 doi: 10.1161/JAHA.116.003205 Impact of Sleep-Disordered Breathing on Long-Term Outcomes in Patients With Acute Coronary Syndrome Who Have Undergone Primary Percutaneous Coronary Intervention Toru Mazaki, Takatoshi Kasai, Hiroyoshi Yokoi, Shoichi Kuramitsu, Kyohei Yamaji, Takashi Morinaga, Hisaki Masuda, Shinichi Shirai, and Kenji Ando e003270 doi: 10.1161/JAHA.116.003270 Systematic Evaluation of the Cellular Innate Immune Response During the Process of Human Atherosclerosis Rogier A. van Dijk, Kevin Rijs, Anouk Wezel, Jaap F. Hamming, Frank D. Kolodgie, Renu Virmani, Alexander F. Schaapherder, and Jan H. N. Lindeman e002860 doi: 10.1161/JAHA.115.002860 Lipoprotein-Associated Phospholipase A2 Activity Is a Marker of Risk But Not a Useful Target for Treatment in Patients With Stable Coronary Heart Disease Lars Wallentin, Claes Held, Paul W. Armstrong, Christopher P. Cannon, Richard Y. Davies, Christopher B. Granger, Emil Hagström, Robert A. Harrington, Judith S. Hochman, Wolfgang Koenig, Sue Krug-Gourley, Emile R. Mohler, III, Agneta Siegbahn, Elizabeth Tarka, Philippe Gabriel Steg, Ralph A. H. Stewart, Robert Weiss, Ollie Östlund, Harvey D. White, and on behalf of the STABILITY Investigators e003407 doi: 10.1161/JAHA.116.003407 Inflammatory Markers Associated With Subclinical Coronary Artery Disease: The Multicenter AIDS Cohort Study Hossein Bahrami, Matthew Budoff, Sabina A. Haberlen, Pantea Rezaeian, Kerunne Ketlogetswe, Russell Tracy, Frank Palella, Mallory D. Witt, Michael V. McConnell, Lawrence Kingsley, and Wendy S. Post e003371 doi: 10.1161/JAHA.116.003371 Epidemiology Ankle Brachial Index and Subsequent Cardiovascular Disease Risk in Patients With Chronic Kidney Disease Jing Chen, Emile R. Mohler, III, Pranav S. Garimella, L. Lee Hamm, Dawei Xie, Stephen Kimmel, Raymond R. Townsend, Matthew Budoff, Qiang Pan, Lisa Nessel, Susan Steigerwalt, Jackson T. Wright, Jiang He, and for the CRIC Investigators e003339 doi: 10.1161/JAHA.116.003339 C-Reactive Protein Identifies Low-Risk Metabolically Healthy Obese Persons: The European Prospective Investigation of Cancer–Norfolk Prospective Population Study Downloaded from http://jaha.ahajournals.org/ by guest on November 20, 2016 Diederik F. van Wijk, S. Matthijs Boekholdt, Benoit J. Arsenault, Sara Ahmadi-Abhari, Nicholas J. Wareham, Erik S. G. Stroes, and Kay-Tee Khaw e002823 doi: 10.1161/JAHA.115.002823 No Decline in the Risk of Stroke Following Incident Atrial Fibrillation Since 2000 in the Community: A Concerning Trend Alanna M. Chamberlain, Robert D. Brown, Jr, Alvaro Alonso, Bernard J. Gersh, Jill M. Killian, Susan A. Weston, and Véronique L. Roger e003408 doi: 10.1161/JAHA.116.003408 Leisure Time Physical Activity and Cardio-Metabolic Health: Results From the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) Xiaochen Lin, Sheila M. Alvim, Eduardo J. Simoes, Isabela M. Bensenor, Sandhi M. Barreto, Maria I. Schmidt, Antonio L. Ribeiro, Francisco Pitanga, Maria Conceição C. Almeida, Simin Liu, and Paulo A. Lotufo e003337 doi: 10.1161/JAHA.116.003337 Relationship Between Arterial Access and Outcomes in ST-Elevation Myocardial Infarction With a Pharmacoinvasive Versus Primary Percutaneous Coronary Intervention Strategy: Insights From the STrategic Reperfusion Early After Myocardial Infarction (STREAM) Study Jay Shavadia, Robert Welsh, Anthony Gershlick, Yinggan Zheng, Kurt Huber, Sigrun Halvorsen, Phillipe G. Steg, Frans Van de Werf, Paul W. Armstrong, and for the STREAM Investigators e003559 doi: 10.1161/JAHA.116.003559 Which QT Correction Formulae to Use for QT Monitoring? Bert Vandenberk, Eline Vandael, Tomas Robyns, Joris Vandenberghe, Christophe Garweg, Veerle Foulon, Joris Ector, and Rik Willems e003264 doi: 10.1161/JAHA.116.003264 Sex-Based Disparities in Incidence, Treatment, and Outcomes of Cardiac Arrest in the United States, 2003–2012 Luke K. Kim, Patrick Looser, Rajesh V. Swaminathan, James Horowitz, Oren Friedman, Ji Hae Shin, Robert M. Minutello, Geoffrey Bergman, Harsimran Singh, S. Chiu Wong, and Dmitriy N. Feldman e003704 doi: 10.1161/JAHA.116.003704 Exercise Physiology Submaximal Exercise Systolic Blood Pressure and Heart Rate at 20 Years of Follow-up: Correlates in the Framingham Heart Study Nicole L. Spartano, Asya Lyass, Martin G. Larson, Gregory D. Lewis, and Ramachandran S. Vasan e002821 doi: 10.1161/JAHA.115.002821 Health Services and Outcomes Research Accuracy of ICD-9-CM Codes by Hospital Characteristics and Stroke Severity: Paul Coverdell National Acute Stroke Program Tiffany E. Chang, Judith H. Lichtman, Larry B. Goldstein, and Mary G. George e003056 doi: 10.1161/JAHA.115.003056 Effectiveness and Safety of Dabigatran, Rivaroxaban, and Apixaban Versus Warfarin in Nonvalvular Atrial Fibrillation Xiaoxi Yao, Neena S. Abraham, Lindsey R. Sangaralingham, M. Fernanda Bellolio, Robert D. McBane, Nilay D. Shah, and Peter A. Noseworthy e003725 doi: 10.1161/JAHA.116.003725 Trends in Consent for Clinical Trials in Cardiovascular Disease Louis A. Kerkhoff, Javed Butler, Anita A. Kelkar, Supriya Shore, Candace D. Speight, Louisa K. Wall, and Neal W. Dickert e003582 doi: 10.1161/JAHA.116.003582 Heart Failure High-Sensitivity Troponin: A Clinical Blood Biomarker for Staging Cardiomyopathy in Fabry Disease Nora Seydelmann, Dan Liu, Johannes Krämer, Christiane Drechsler, Kai Hu, Peter Nordbeck, Andreas Schneider, Stefan Störk, Bart Bijnens, Georg Ertl, Christoph Wanner, and Frank Weidemann e002839 doi: 10.1161/JAHA.115.002839 Downloaded from http://jaha.ahajournals.org/ by guest on November 20, 2016 ECG Criteria to Differentiate Between Takotsubo (Stress) Cardiomyopathy and Myocardial Infarction Antonio H. Frangieh, Slayman Obeid, Jelena-Rima Ghadri, Yoichi Imori, Fabrizio D’Ascenzo, Marc Kovac, Frank Ruschitzka, Thomas F. Lüscher, Firat Duru, Christian Templin, and on behalf of the InterTAK Collaborators e003418 doi: 10.1161/JAHA.116.003418 Predicting Outcomes Over Time in Patients With Heart Failure, Left Ventricular Systolic Dysfunction, or Both Following Acute Myocardial Infarction Renato D. Lopes, Karen S. Pieper, Susanna R. Stevens, Scott D. Solomon, John J.V. McMurray, Marc A. Pfeffer, Jeffrey D. Leimberger, and Eric J. Velazquez e003045 doi: 10.1161/JAHA.115.003045 Hypertension Restoration of Mitochondrial Cardiolipin Attenuates Cardiac Damage in Swine Renovascular Hypertension Alfonso Eirin, Behzad Ebrahimi, Soon Hyo Kwon, Justin A. Fiala, Barbara J. Williams, John R. Woollard, Quan He, Ramech C. Gupta, Hani N. Sabbah, Y.S. Prakash, Stephen C. Textor, Amir Lerman, and Lilach O. Lerman e003118 doi: 10.1161/JAHA.115.003118 Imaging Coronary Computed Tomography (CT) Angiography as a Predictor of Cardiac and Noncardiac Vascular Events in Asymptomatic Type 2 Diabetics: A 7-Year Population-Based Cohort Study David A. Halon, Mali Azencot, Ronen Rubinshtein, Barak Zafrir, Moshe Y. Flugelman, and Basil S. Lewis e003226 doi: 10.1161/JAHA.116.003226 Infarct Size Following Treatment With Second- Versus Third-Generation P2Y12 Antagonists in Patients With Multivessel Coronary Disease at ST-Segment Elevation Myocardial Infarction in the CvLPRIT Study Jamal N. Khan, John P. Greenwood, Sheraz A. Nazir, Florence Y. Lai, Miles Dalby, Nick Curzen, Simon Hetherington, Damian J. Kelly, Daniel Blackman, Charles Peebles, Joyce Wong, Marcus Flather, Howard Swanton, Anthony H. Gershlick, and Gerry P. McCann e003403 doi: 10.1161/JAHA.116.003403 Interventional Cardiology Excessively High Hydration Volume May Not Be Associated With Decreased Risk of Contrast-Induced Acute Kidney Injury After Percutaneous Coronary Intervention in Patients With Renal Insufficiency Yong Liu, Hualong Li, Shiqun Chen, Jiyan Chen, Ning Tan, Yingling Zhou, Yuanhui Liu, Piao Ye, Peng Ran, Chongyang Duan, and Pingyan Chen e003171 doi: 10.1161/JAHA.115.003171 Impact of Center Experience on Patient Radiation Exposure During Transradial Coronary Angiography and Percutaneous Intervention: A Patient-Level, International, Collaborative, Multi-Center Analysis Trevor Simard, Benjamin Hibbert, Madhu K. Natarajan, Mathew Mercuri, Simon L. Hetherington, Robert Wright, Ronak Delewi, Jan J. Piek, Ralf Lehmann, Zoltán Ruzsa, Helmut W. Lange, Håkan Geijer, Michael Sandborg, Vinay Kansal, Jordan Bernick, Pietro Di Santo, Ali Pourdjabbar, F. Daniel Ramirez, Benjamin J. W. Chow, Aun Yeong Chong, Marino Labinaz, Michel R. Le May, Edward R. O’Brien, George A. Wells, and Derek So e003333 doi: 10.1161/JAHA.116.003333 Value of Image Fusion in Coronary Angiography for the Detection of Coronary Artery Bypass Grafts Julien Plessis, Karine Warin Fresse, Zachary Cahouch, Thibaut Manigold, Vincent Letocart, Laurianne Le Gloan, Béatrice Guyomarch, and Patrice Guerin e002233 doi: 10.1161/JAHA.115.002233 Transcatheter Aortic Valve Implantation With or Without Preimplantation Balloon Aortic Valvuloplasty: A Systematic Review and Meta-Analysis Rodrigo Bagur, Chun Shing Kwok, Luis Nombela-Franco, Peter F. Ludman, Mark A. de Belder, Sandro Sponga, Mark Gunning, James Nolan, Pantelis Diamantouros, Patrick J. Teefy, Bob Kiaii, Michael W. A. Chu, and Mamas A. Mamas e003191 doi: 10.1161/JAHA.115.003191 Impaired Peripheral Endothelial Function Assessed by Digital Reactive Hyperemia Peripheral Arterial Tonometry and Risk of In-Stent Restenosis Downloaded from http://jaha.ahajournals.org/ by guest on November 20, 2016 Naohiro Komura, Kenichi Tsujita, Kenshi Yamanaga, Kenji Sakamoto, Koichi Kaikita, Seiji Hokimoto, Satomi Iwashita, Takashi Miyazaki, Tomonori Akasaka, Yuichiro Arima, Eiichiro Yamamoto, Yasuhiro Izumiya, Megumi Yamamuro, Sunao Kojima, Shinji Tayama, Seigo Sugiyama, Kunihiko Matsui, Sunao Nakamura, Kiyoshi Hibi, Kazuo Kimura, Satoshi Umemura, and Hisao Ogawa e003202 doi: 10.1161/JAHA.116.003202 Outcome of 1051 Octogenarian Patients With ST-Segment Elevation Myocardial Infarction Treated With Primary Percutaneous Coronary Intervention: Observational Cohort From the London Heart Attack Group Daniel I. Bromage, Daniel A. Jones, Krishnaraj S. Rathod, Claire Grout, M. Bilal Iqbal, Pitt Lim, Ajay Jain, Sundeep S. Kalra, Tom Crake, Zoe Astroulakis, Mick Ozkor, Roby D. Rakhit, Charles J. Knight, Miles C. Dalby, Iqbal S. Malik, Anthony Mathur, Simon Redwood, Philip A. MacCarthy, and Andrew Wragg e003027 doi: 10.1161/JAHA.115.003027 Kidney in Cardiovascular Disease Cigarette Smoking and Chronic Kidney Disease in African Americans in the Jackson Heart Study Michael E. Hall, Wei Wang, Victoria Okhomina, Mohit Agarwal, John E. Hall, Albert W. Dreisbach, Luis A. Juncos, Michael D. Winniford, Thomas J. Payne, Rose M. Robertson, Aruni Bhatnagar, and Bessie A. Young e003280 doi: 10.1161/JAHA.116.003280 Molecular Cardiology Postnatal Development of Right Ventricular Myofibrillar Biomechanics in Relation to the Sarcomeric Protein Phenotype in Pediatric Patients with Conotruncal Heart Defects Fatiha Elhamine, Bogdan Iorga, Martina Krüger, Mona Hunger, Jan Eckhardt, Narayanswami Sreeram, Gerardus Bennink, Konrad Brockmeier, Gabriele Pfitzer, and Robert Stehle e003699 doi: 10.1161/JAHA.116.003699 Pediatric Cardiology Implantable Loop Recorder Monitoring for Refining Management of Children With Inherited Arrhythmia Syndromes Jennifer N. Avari Silva, Burt I. Bromberg, Fredrick K. Emge, Tammy M. Bowman, and George F. Van Hare e003632 doi: 10.1161/JAHA.116.003632 Preventive Cardiology Novel Biomarkers to Improve the Prediction of Cardiovascular Event Risk in Type 2 Diabetes Mellitus Joep van der Leeuw, Joline W. J. Beulens, Susan van Dieren, Casper G. Schalkwijk, Jan F. C. Glatz, Marten H. Hofker, W. M. Monique Verschuren, Jolanda M. A. Boer, Yolanda van der Graaf, Frank L. J. Visseren, Linda M. Peelen, and Yvonne T. van der Schouw e003048 doi: 10.1161/JAHA.116.003048 Resuscitation Science Minnesota Resuscitation Consortium’s Advanced Perfusion and Reperfusion Cardiac Life Support Strategy for Out-of-Hospital Refractory Ventricular Fibrillation Demetris Yannopoulos, Jason A. Bartos, Cindy Martin, Ganesh Raveendran, Emil Missov, Marc Conterato, R. J. Frascone, Alexander Trembley, Kevin Sipprell, Ranjit John, Stephen George, Kathleen Carlson, Melissa E. Brunsvold, Santiago Garcia, and Tom P. Aufderheide e003732 doi: 10.1161/JAHA.116.003732 Vascular Medicine Vascular Regeneration in Ischemic Hindlimb by Adeno-Associated Virus Expressing Conditionally Silenced Vascular Endothelial Growth Factor Jeffrey Boden, Roberta Marques Lassance-Soares, Huilan Wang, Yuntao Wei, Maria-Grazia Spiga, Jennipher Adi, Hans Layman, Hong Yu, Roberto I. Vazquez-Padron, Fotios Andreopoulos, and Keith A. Webster e001815 doi: 10.1161/JAHA.115.001815 Monosialoganglioside-Containing Nanoliposomes Restore Endothelial Function Impaired by AL Amyloidosis Light Chain Proteins Daniel A. Franco, Seth Truran, Volkmar Weissig, Diana Guzman-Villanueva, Nina Karamanova, Subhadip Senapati, Camelia Burciu, Marina Ramirez-Alvarado, Luis M. Blancas-Mejia, Stuart Lindsay, Parameswaran Hari, and Raymond Q. Migrino e003318 doi: 10.1161/JAHA.116.003318 Downloaded from http://jaha.ahajournals.org/ by guest on November 20, 2016 High-Fat-Diet Intake Enhances Cerebral Amyloid Angiopathy and Cognitive Impairment in a Mouse Model of Alzheimer’s Disease, Independently of Metabolic Disorders Bowen Lin, Yu Hasegawa, Koki Takane, Nobutaka Koibuchi, Cheng Cao, and Shokei Kim-Mitsuyama e003154 doi: 10.1161/JAHA.115.003154 Increased Cardiac Workload in the Upright Posture in Men: Noninvasive Hemodynamics in Men Versus Women Pauliina Kangas, Anna Tahvanainen, Antti Tikkakoski, Jenni Koskela, Marko Uitto, Jari Viik, Mika Kähönen, Tiit Kööbi, Jukka Mustonen, and Ilkka Pörsti e002883 doi: 10.1161/JAHA.115.002883 Cystatin C Predicts Incident Cardiovascular Disease in Twins Johannes Arpegård, Patrik K. E. Magnusson, Xu Chen, Peter Ridefelt, Nancy L. Pedersen, Ulf De Faire, and Per Svensson e003085 doi: 10.1161/JAHA.115.003085 Basic Science for Clinicians Cardiac-Secreted Factors as Peripheral Metabolic Regulators and Potential Disease Biomarkers Colleen M. Dewey, Kathryn M. Spitler, Jessica M. Ponce, Duane D. Hall, and Chad E. Grueter e003101 doi: 10.1161/JAHA.115.003101 Contemporary Review Sedation in the Electrophysiology Laboratory: A Multidisciplinary Review Neal S. Gerstein, Andrew Young, Peter M. Schulman, Eric C. Stecker, and Peter M. Jessel e003629 doi: 10.1161/JAHA.116.003629 Corrections Functional Analysis of the TRIB1 Associated Locus Linked to Plasma Triglycerides and Coronary Artery Disease e002056 doi: 10.1161/JAHA.116.002056 Angiotensin-Converting Enzyme Inhibitor Initiation and Dose Uptitration in Children With Cardiovascular Disease: A Retrospective Review of Standard Clinical Practice and a Prospective Randomized Clinical Trial e002067 doi: 10.1161/JAHA.116.002067 Association Between Severe Hypoglycemia and Cardiovascular Disease Risk in Japanese Patients With Type 2 Diabetes e002075 doi: 10.1161/JAHA.116.002075 5 (6) J Am Heart Assoc. 2016;5:; originally published June 1, 2016; Downloaded from http://jaha.ahajournals.org/ by guest on November 20, 2016 The Journal of the American Heart Association is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Online ISSN: 2047-9980 The online version of this article, along with updated information and services, is located on the World Wide Web at: http://jaha.ahajournals.org/content/5/6.citation Subscriptions, Permissions, and Reprints: The Journal of the American Heart Association is an online only Open Access publication. Visit the Journal at http://jaha.ahajournals.org for more information.