The PSPN - Nanosafe

05/11/08
Development of a confinement solution for
laboratories and small industrial applications
Presentation
of FAURE Ingénierie’s
safety cabinet
for nanostructured
particles : The PSPN
P. BOMBARDIER / J.M. REINWALT
28/10/2008
2 professions to be successful
Conception &
realization of clean
controlled environment
Pharmaceutics
High tech fields
!THE COMPANY
Electronics
Food & other
related industries
Engineering
!NANO ACTIVITIES
Hook-up, revamping,
etc.
! PSPN CABINET OBECTIVES
!THE PSPN CONCEPT
Solution development
and optimization (R&D)
!PSPN DESCRIPTION
Customers training
!PERFORMANCE TESTING
France,
!EVOLUTION
Switzerland,
Canada,
Metrology
Performance/
compliance tests / Fluids
quality monitoring
Morocco,
Singapore
Contamination expertise
Sensors calibration
Page 2/12
28/10/2008
Activities in the field of Nanotechnology
!THE COMPANY
• Conception of laboratories
dedicated to nanoparticles
handling.
!NANO ACTIVITIES
! PSPN CABINET OBECTIVES
!THE PSPN CONCEPT
• Conception of safety cabinet and
exhausting systems.
!PSPN DESCRIPTION
!PERFORMANCE TESTING
• Qualification and performance test
of controlled environment
dedicated to nanoparticles.
!EVOLUTION
• Audit, staff training, development of
methods.
Page 3/12
28/10/2008
For What ?
!THE COMPANY
Safe handling of dry
powders and wet
suspension of nanoparticles
or nanostructured particles.
!NANO ACTIVITIES
! PSPN CABINET OBECTIVES
!THE PSPN CONCEPT
Protection of the working
surface from outside
contamination.
!PSPN DESCRIPTION
!PERFORMANCE TESTING
Protection of the outside
environment.
!EVOLUTION
Simplicity of use and
cleaning for multi-user
environment.
Page 4/12
28/10/2008
How-to ?
On the basis of microbial safety cabinet, the PSPN improve :
!THE COMPANY
!NANO ACTIVITIES
• filtration efficiency
• security survey systems
! PSPN CABINET OBECTIVES
!THE PSPN CONCEPT
• cleaning ability
• possibility of extension and modification of the work surface.
• testing operations (injection and test port implemented)
!PSPN DESCRIPTION
• the safety during operations on recycled air filters.
!PERFORMANCE TESTING
!EVOLUTION
Page 5/12
28/10/2008
How-to?
A computational fluid dynamic (CFD) software is used to define
the internal geometries :
• Holes position and size around the useful work surface.
!THE COMPANY
!NANO ACTIVITIES
• Airflow behavior with
•large equipment inside (weighing machine, etc…).
•an operator in front of the PSPN.
! PSPN CABINET OBECTIVES
!THE PSPN CONCEPT
!PSPN DESCRIPTION
•an external airflow (horizontal or vertical).
• Definition of the good adjustments for the air speed
(blowing and aspiration) and security limits for these
parameters.
!PERFORMANCE TESTING
!EVOLUTION
Page 6/12
28/10/2008
How-to ?
Homogeneity in
the entrance area
!THE COMPANY
!NANO ACTIVITIES
No cross-contamination
between coupled PSPN
! PSPN CABINET OBECTIVES
!THE PSPN CONCEPT
Contamination
quickly evacuated
!PSPN DESCRIPTION
!PERFORMANCE TESTING
!EVOLUTION
Page 7/12
28/10/2008
Technical choices
The main characteristics are :
• ISO 5 particulate class.
!THE COMPANY
• Stainless steel conditioned to reduce the particle adherence.
!NANO ACTIVITIES
• Coupled solutions with possibility to add fluid tubing inside.
• 3 worktop (tank-like ; perforated or marble made for stability).
! PSPN CABINET OBECTIVES
!THE PSPN CONCEPT
!PSPN DESCRIPTION
!PERFORMANCE TESTING
• 3 ULPA filters to obtain a full containment of nanoparticules.
• Individual selection of filters for the best blowing homogeneity.
• High cleanliness demanded for the delivered systems.
• Sensitive alarm systems (inside overpressure survey and filters head loss
indicators).
!EVOLUTION
High safety level
Page 8/12
28/10/2008
Qualification of prototype
!THE COMPANY
!NANO ACTIVITIES
! PSPN CABINET OBECTIVES
!THE PSPN CONCEPT
!PSPN DESCRIPTION
!PERFORMANCE TESTING
!EVOLUTION
The special following tests where passed
successfully :
• Conformance with the objective of
0,0025% max leak level for all
particle sizes (5 to 300 nm). The
filters and the whole structure were
tested.
• Nanoparticles emitted inside are
not detected outside of the front
access
(tested
with
carbon
nanoparticles, a CNC and a SMPS).
• The value and homogeneity of air
speed is tested inside the PSPN and
in the entrance area to verify that
we respect the criteria
± 20%
around the mean value.
Page 9/12
28/10/2008
Qualification of standard equipments
!THE COMPANY
The standard performance test
include :
!NANO ACTIVITIES
• Max outside airflow < 15
cm/s.
! PSPN CABINET OBECTIVES
• Air speed adjustment and
homogeneity testing.
!THE PSPN CONCEPT
!PSPN DESCRIPTION
!PERFORMANCE TESTING
!EVOLUTION
• Leak test (with 0,3 µm
particles) of filters and
structure.
• Cleanliness class inside and
outside the PSPN.
• Alarm set off when a
default is triggered.
• Absence of any retention
zone inside (fog test with
CO2 + H20).
Page 10/12
28/10/2008
Evolution
To satisfy all needs we propose
the following version :
!THE COMPANY
!NANO ACTIVITIES
! PSPN CABINET OBECTIVES
• A simple extraction hood
with the same safety level
as the first PSPN.
• A cabin-like extended
version to protect large
operations.
!THE PSPN CONCEPT
!PSPN DESCRIPTION
Possible adaptations :
• Fluid supply.
!PERFORMANCE TESTING
!EVOLUTION
• Small sink for liquids.
• Special worktop for
vibrating systems.
Page 11/12
28/10/2008
Range of safety systems
Product sensitivity to
contamination
!THE COMPANY
Current
PSPN
!NANO ACTIVITIES
Insulator
! PSPN CABINET OBECTIVES
!THE PSPN CONCEPT
!PSPN DESCRIPTION
!PERFORMANCE TESTING
!EVOLUTION
Traditional
safety
cabinet
Extraction
only PSPN
Safety level needed
Page 12/12
05/11/08
THANK YOU FOR YOUR ATTENTION
Pierre BOMBARDIER – Laboratory Manager
Jean Marie REINWALT – Commercial and Marketing Manager
www.faureingenierie.com
www.pspn.fr