ProThera Professional Catalog 2013
Transcription
ProThera Professional Catalog 2013
About ProThera® ProThera, Inc. manufactures a comprehensive line of nutraceutical products for exclusive distribution by healthcare professionals. Products are designed for medical applications based on 50 years of combined formulation experience by the company’s founders, Dennis Meiss, PhD and Janet Ralston, BS, in close association with an advisory board of medical consultants with extensive clinical experience in nutritional medicine. A coordinated group of multinutrient products forms the core of the ProThera product line, with special emphasis on avoiding nutrient redundancy, maintaining cost-effectiveness, and encouraging patient compliance. ProThera’s Klaire Labs® division offers dairy-free probiotics and other products to support gastrointestinal and immune system health. Flexibility, rapid-response times, and personalized attention to the individual needs of healthcare professionals describe ProThera’s underlying service philosophy. Headquartered in Reno, Nevada, ProThera operates world-wide through international partners in Brazil, Canada, Japan, the Netherlands, Singapore, Hong Kong, Spain, Turkey, and the United Kingdom. This catalog describes the ProThera product line. The Klaire Labs catalog is available on request. ProThera and Klaire Labs products can be ordered and shipped together by calling one convenient toll-free number at 888-488-2488. A Professional Perspective Healthcare professionals today are charged with the responsibility of helping patients understand that adequate nutrition is crucial to maintaining health and recovering from illness. This professional guidance often encompasses recommending appropriate dietary supplements to address individual needs and produce successful clinical outcomes. Yet, sorting through the myriad of product choices from different companies to create costeffective programs that also encourage patient compliance is often difficult. ProThera recognizes the challenges that healthcare professionals face in integrating nutritional support into office settings. Assurance of product quality, safe and welltolerated nutritional ingredients with scientific documentation of efficacy, accessible technical support, affordable pricing, and prompt, reliable service are each crucial to retaining patient confidence in the recommendations of the healthcare professional. Above all, we know that just as each patient has individual requirements, each practitioner has different issues that require personalized attention and service. Our integrated line of nutraceutical products and the customized labeling and formulation service options presented in this catalog reflect ProThera’s commitment to providing healthcare professionals and their patients the prompt and reliable assistance they need. Table of Contents General Information Manufacturing Overview...................... 46 Supplement Packets ........................ 48-49 Order Information .............................. 51 Technical Support .................................. 8 Index .............................................. 50-51 Product Information Adrenal Function ................................ 36 Amino Acids ...................................... 34 Antioxidants and Vitamins .................... 11 B-Complex Vitamins.......................... 9-11 Calcium and Magnesium ................ 38-39 Cardiovascular Support .................. 18-19 CoEnzyme Q10 .................................... 16-17 Enzymes ..........................................22-23 Fatty Acids .................................... 26-29 Flavonoid Antioxidants.................... 12-13 Gastrointestinal Support ................ 20-21 Glucose Metabolism ...................... 14-15 Hormones .......................................... 37 Immune Function .......................... 23-24 Inflammation Support .................... 30-31 Joint/Connective Tissue Function ............ 30 Klaire Labs® ........................................ 43 Liver Function ................................ 24-25 Men’s Health ........................................ 37 Minerals and Trace Elements .......... 40-41 Multiple Vitamin/Mineral Supplements .... 4-8 NeuroNutrients .............................. 32-33 Ocular Health .................................... 14 Oral Care ............................................ 42 Skin Health ........................................ 42 Weight Management ............................ 35 Women’s Health .................................. 36 Special Services Personalized Supplement Packets .... 45-46 Private Labeling .............................. 44-45 Custom Formulation Services .............. 47 cGMP Manufacturing ProThera products are made according to strict current Good Manufacturing Practices (cGMPs) and adherence to USP standards. Licensed by the State of California and registered with the Food and Drug Administration as a drug manufacturer, the facility is also approved by agencies in the United Kingdom and European Community (EC). ProThera operates a GMP 9000 registered facility certified by NSF International, an independent, third-party certification organization. GMP 9000 registration integrates both ISO 9001 and GMP registration. 2 Other Benefits • No minimum order required • Most orders shipped same day if received by 12 pm Pacific time • All orders shipped to arrive within 1-3 days (within U.S.) Contact ProThera® • Volume discounts available Toll-Free 888-488-2488 • Sold exclusively to healthcare professionals and authorized patients Main 775-850-8800 Fax 775-850-8810 www.protherainc.com An Integrated Approach ProThera dietary supplements are carefully designed to maximize the synergism between nutrients in a cost-effective fashion. Each multi-nutrient formula coordinates with MultiThera® — our comprehensive, high-potency multiple vitamin/mineral supplement — thus creating an integrated approach to dietary supplementation that is often more complete while using fewer pills at lower cost. Ensuring micronutrient essentials We have formulated MultiThera® to be the cornerstone of each patient’s nutritional program. These essential nutrients form a sound nutritional platform of 30 vitamins, minerals, and trace elements on which to build patient-specific programs. Synchronized formulations create a balanced, modular system ProThera has created a core group of combination nutrient products that address a variety of metabolic concerns. These can be used together with MultiThera® and with each other without conflict to create potent, biocompatible dietary supplement programs for various medical applications. Related nutrients are combined for enhanced benefit and all formulations are synchronized to avoid redundancy. Nutrients providing the best documented actions and cost-effectiveness are selected for use in ProThera products and included in amounts and potencies as supported by clinical studies. The end result is an integrated product line offering a more concentrated and less costly multifunctional approach. Product Availability For Office Dispensaries ProThera labeled products are sold exclusively to licensed healthcare professionals at wholesale prices for resale to patients.* Private Labeling Option Private labeling services and custom supplement packets are available in two business days at no extra charge for 12 bottles or more per product. See pages 44-45 for full information. For Authorized Patients Healthcare professionals who do not dispense or wish to provide patients with alternate access to ProThera products may obtain an authorization code for patient-direct ordering from ProThera. Suggested retail prices apply to patient orders. *ProThera® brand products are sold under the condition that they are not resold on the Internet or in retail outlets. 3 Multiple Vitamin/Mineral Supplements MultiThera® THE ESSENTIAL FOUNDATION Your first choice for ensuring daily micronutrient intake. We recommend this versatile, high-potency multiple vitamin and mineral formula as the primary dietary supplement for all types of patients. It is formulated based on many years of clinical experience with similar products, and improved with the inclusion of nutrient forms that provide even greater documented bioavailability and benefit. MultiThera® contains well-absorbed forms and nutritionally meaningful amounts of 30 essential vitamins, minerals, and trace elements in six tablets or capsules daily. All MultiThera® formulas are free of common allergens, artificial flavors, preservatives, and colorings. Each of these full-spectrum formulas contain: More complete “families” of nutrients for natural balance and safety • 100% natural vitamin E complex, including all mixed tocopherol isomers (d-alpha, d-beta, d-gamma, and d-delta), provides broader antioxidant protection • Both preformed, vitamin A (retinol) and its carotene precursors extend more complete vitamin A nutrition • All-natural mixed carotenoids, including alpha- and beta-carotenes, lutein, zeaxanthin, and beta-cryptoxanthin, offer more diverse benefit and are safer than synthetic beta-carotene alone • Complete vitamin B-complex supports many metabolic functions and includes significant amounts of B-vitamins most crucial to helping maintain normal homocysteine metabolism • Vitamins K1 and K2 (as menaquinone-7) support blood coagulation and bone metabolism (vitamin K is excluded from MultiThera® 1 Capsule Formula (MT1C) option, p6) Activated folate and vitamin B12 for highest absorption and bioavailability • Metafolin®** L-5-methyltetrahydrofolate (L-5-MTHF), a bioactive form of folate, unlike folic acid is absorbed and utilized directly and is the most beneficial form for patients with elevated homocysteine resulting from compromised utilization of folate • Methylcobalamin and 5-adenosylcobalamin, the active forms of vitamin B12, are the most reliable oral forms of this difficult-to-absorb nutrient Extra vitamin D3 to optimize daily intake for broad physiological benefit • Natural vitamin D3 is included at 1,000 IU daily, a higher amount than typically found in daily multivitamins, to help achieve optimal intakes now recognized to support bone health as well as its numerous roles in tissues throughout the body Mineral and trace element compounds with validated bioavailability • True amino acid chelates from Albion® Laboratories are fully-reacted, low molecular weight mineral compounds with exceptional tolerance and documented bioavailability • Calcium citrate-malate is a well-studied calcium compound with higher absorption and effectiveness than many other calcium sources • Organically-bound chromium and vanadium complexes offer high physiological activity COMPREHENSIVE FORMULAS WITH MULTIDIMENSIONAL CLINICAL APPLICATIONS Cellular antioxidant protection Vitamin E, C, beta-carotene, selenium Cardiovascular function Vitamin E, magnesium, potassium, selenium Nervous system support Vitamin B1, B6, B12, choline, calcium, magnesium Homocysteine regulation Vitamin B12, B6, folate Visual function Vitamin A, mixed carotenoids, zinc Bone health Calcium, magnesium, vitamin D, vitamin K, boron, manganese Connective tissue function Vitamin C, bioflavonoids, copper, manganese, zinc Blood glucose regulation Chromium, biotin, niacinamide, manganese, vanadium Energy metabolism Vitamin B1, B2, niacin, pantothenic acid, magnesium, iron Adrenal gland function Pantothenic acid, vitamin C Immune system enhancement Vitamin A, C, E, zinc, selenium Capillary integrity Bioflavonoids Cholesterol metabolism Niacin, vitamin C, E, chromium, vanadium Thyroid function Iodine, selenium, copper 4 It is well known that obtaining an adequate daily intake of essential vitamins, minerals, and trace elements is a requirement everyone has in common. Since the human body cannot produce these crucial micronutrients on its own, we must obtain them from our diet. The widespread popularity of multiple vitamin supplements shows that many people recognize this type of product can provide an extra measure of nutritional insurance. Yet, ensuring that a daily multivitamin and mineral supplement can continue to be safely taken as the cornerstone of a well-rounded nutritional supplementation program when other supplements are added to it, is often overlooked. While many companies refer to their multiple as the foundation of the product line, their combination products formulated for specific health concerns don’t remain true to a coordinated approach. ProThera doesn’t duplicate use of nutrients provided by MultiThera® in our other combination products unless additional amounts are warranted to address higher requirements in specific patient populations. This approach preserves a healthy balance of essential nutrients, avoids redundancy, and keeps both the total number of pills and the costs more tightly controlled. Multiple Vitamin/Mineral Supplements MultiThera® 1 MultiThera® 1 (Iron-Free) Formula Supplement Facts Our most widely-preferred multiple formula. Iron-free. Serving Size 6 Tablets Amount Per 6 Tablets % Daily Value Vitamin A (86% (15,000 IU) as natural 17,500 IU 350% carotenes (alpha, beta, beta-cryptoxanthin, zeaxanthin, and lutein) from D. salina and 14% (2,500 IU) as vitamin A palmitate) Vitamin C (as calcium ascorbate and 1,200 mg 2000% magnesium-potassium ascorbate complex) Vitamin D3 (as cholecalciferol) 1,000 IU 250% Vitamin E (as d-alpha tocopheryl succinate plus natural 400 IU 1333% mixed tocopherols d-alpha, d-beta, d-delta, d-gamma) from soy Vitamin K (67% as vitamin K1 phytonadione and 60 mcg 33% as vitamin K2 menaquinone-7) Thiamine (as thiamine hydrochloride USP) 100 mg Riboflavin (as riboflavin USP) 50 mg Niacin (75% as niacinamide USP and 25% 200 mg as niacin USP) Vitamin B6 (as pyridoxine hydrochloride USP) 50 mg Folate (as Metafolin®** L-5-methyltetrahydrofolate) 800 mcg Vitamin B12 (50% as methylcobalamin and 200 mcg 50% as 5-adenosylcobalamin) Biotin USP 300 mcg Pantothenic Acid (as d-calcium pantothenate USP) 400 mg Calcium (76% as calcium citrate-malate and 500 mg 24% as calcium ascorbate) Iodine (from kelp) 150 mcg Magnesium (75% as magnesium aspartate500 mg ascorbate complex and 25% as magnesium bisglycinate chelate***) Zinc (as zinc bisglycinate chelate***) 20 mg Selenium (as L-selenomethionine) 200 mcg Copper (as copper bisglycinate chelate***) 2 mg Manganese (as manganese bisglycinate chelate***) 2 mg Chromium (as chromium nicotinate 200 mcg glycinate chelate***) Molybdenum (as molybdenum glycinate chelate***) 150 mcg Potassium (as potassium ascorbate-aspartate complex) 99 mg 75% 6667% 2941% 1000% 2500% 200% 3333% 100% 4000% 50% The amounts and ratios of nutrients used in this MultiThera® formula are based on a long history of clinical use and updated using the newest research findings. The 1:1 calcium to magnesium ratio, high-potencies of vitamins E, C, D3 and B-complex, bioactive forms of folate and vitamin B12, extra pantothenic acid for adrenal support, and full complement of trace elements distinguish this formula from ordinary multiple vitamins. This iron-free formula option is most suitable for the majority of patients. Supplemental iron is unnecessary for most adult men and women and may be potentially harmful, as excessive amounts have been associated with heart disease, arthritis, and cellular damage. Copper is included because of its importance for SOD antioxidant enzyme activity and to maintain a healthy balance with zinc. This concentrated formula is designed to fit into six tablets daily. A clear, water-soluble cellulose coating protects the stability of the nutritional ingredients and makes the tablets easy to swallow. Each batch is tested using USP protocols to ensure tablet disintegration time of 45 minutes or less to help maximize nutrient bioavailability. MultiThera® 1 is especially recommended for men, postmenopausal women, and women with light or normal menstrual flow who may not need supplemental iron. SUGGESTED USE: 3 tablets twice daily with food. MT1 180 tablets 100% 125% 133% 286% 100% 100% 167% 200% 3% Boron (as boron aspartate-citrate) 2 mg Vanadium (as bisglycinato oxovanadium) 100 mcg Choline (as choline bitartrate) 150 mg Inositol 50 mg para-Aminobenzoic Acid USP 50 mg Citrus Bioflavonoids (85 mg as citrus bioflavonoid 100 mg complex, min. 50% bioflavonoids, and 15 mg as hesperidin methylchalcone) * * * * * * Every batch of ProThera tablets and capsules is tested using the official US Pharmacopeia (USP) testing method to ensure appropriate and reliable disintegration. MultiThera® 2 Iron-fortified formula. Adolescents, women with a heavy menstrual flow, and others with a documented need for supplemental iron are the best candidates for this iron-containing version of MultiThera®. We use Albion’s iron amino acid chelate, a bisglycinate compound with exceptional GI tolerance and bioavailability. MultiThera® 2 is identical in all other respects to MultiThera® 1 tablet formula. SUGGESTED USE: 3 tablets twice daily with food. *Daily Value not established. Other ingredients: Cellulose, carboxymethylcellulose sodium, silicon dioxide, vegetable stearine, vegetable gum, magnesium stearate, natural citrus flavor, and cellulose coating. **Metafolin® is a registered trademark of Merck KGaA, Darmstadt, Germany ***Albion® Laboratories ® MT2 180 tablets MultiThera® 2 (Plus Iron) Formula Supplement Facts Serving Size 6 Tablets MultiThera® 1 (Iron-Free) is also available in vegetarian capsule formula options. Please see description on page 6. Order ProThera and Klaire Labs products TOLL-FREE 7:30 AM • 5 PM Pacific time 888-488-2488 Amount Per 6 Tablets % Daily Value Amount Per 6 Tablets % Daily Value Vitamin A (86% (15,000 IU) as natural 17,500 IU 350% carotenes (alpha, beta, beta-cryptoxanthin, zeaxanthin, and lutein) from D. salina and 14% (2,500 IU) as vitamin A palmitate) Vitamin C (as calcium ascorbate and 1,200 mg 2000% magnesium-potassium ascorbate complex) Vitamin D3 (as cholecalciferol) 1,000 IU 250% Vitamin E (as d-alpha tocopheryl succinate plus natural 400 IU 1333% mixed tocopherols d-alpha, d-beta, d-delta, d-gamma) from soy Vitamin K (67% as vitamin K1 phytonadione and 60 mcg 75% 33% as vitamin K2 menaquinone-7) Thiamine (as thiamine hydrochloride USP) 100 mg 6667% Riboflavin (as riboflavin USP) 50 mg 2941% Niacin (75% as niacinamide USP and 25% as 200 mg 1000% niacin USP) Vitamin B6 (as pyridoxine hydrochloride USP) 50 mg 2500% Folate (as Metafolin®** L-5-methyltetrahydrofolate) 800 mcg 200% Vitamin B12 (50% as methylcobalamin and 200 mcg 3333% 50% as 5-adenosylcobalamin) Biotin USP 300 mcg 100% Pantothenic Acid (as d-calcium pantothenate USP) 400 mg 4000% Calcium (76% as calcium citrate-malate and 500 mg 50% 24% as calcium ascorbate) Iron (as Ferrochel® ferrous bisglycinate chelate***) 20 mg Iodine (from kelp) 150 mcg Magnesium (75% as magnesium aspartate-ascorbate 500 mg complex and 25% as magnesium bisglycinate chelate***) Zinc (as zinc bisglycinate chelate***) 20 mg Selenium (as L-selenomethionine) 200 mcg Copper (as copper bisglycinate chelate***) 2 mg Manganese (as manganese bisglycinate chelate***) 2 mg Chromium (as chromium nicotinate 200 mcg glycinate chelate***) Molybdenum (as molybdenum glycinate chelate***) 150 mcg Potassium (as potassium aspartate-ascorbate complex)99 mg Other ingredients: Cellulose, carboxymethylcellulose sodium, silicon dioxide, vegetable stearine, magnesium stearate, vegetable gum, natural citrus flavor, and cellulose coating. **Metafolin® is a registered trademark of Merck KGaA, Darmstadt, Germany ***Albion® Laboratories Boron (as boron aspartate-citrate) 2 mg Vanadium (as bisglycinato oxovanadium) 100 mcg Choline (as choline bitartrate) 150 mg Inositol 50 mg para-Aminobenzoic Acid USP 50 mg Citrus Bioflavonoids (85 mg as citrus bioflavonoid 100 mg complex, min. 50% bioflavonoids, and 15 mg as hesperidin methylchalcone) 111% 100% 125% 133% 286% 100% 100% 167% 200% 3% * * * * * * *Daily Value not established. ® 5 Multiple Vitamin/Mineral Supplements MultiThera® 1 Capsule Formula MultiThera® 3 This comprehensive multiple vitamin/mineral supplement is similar to our MultiThera® 1 tablet formula, but the amounts of calcium, magnesium, and several other nutrients have been reduced to ensure the formula will fit into six capsules daily to maintain patient compliance. MultiThera® 1 Capsule Formula retains the important balance of fat-and water-soluble antioxidants, B-complex vitamins, and other nutrients of a sound nutritional foundation. As with MultiThera® tablet formulas, activated forms of folate (Metafolin®** L-5-methyltetrahydrofolate) and vitamin B12 (methylcobalamin and 5-adenosylcobalamin) are used for enhanced absorption and bioactivity. MultiThera® 1 capsules contain a full-spectrum of bioavailable trace elements, excluding iron. Vitamin K is an optional ingredient in this formula, making it suitable for patients using anticoagulant medications who wish to avoid taking this nutrient. Vegetarian capsules made of plant cellulose are used for MultiThera® 1 and all other encapsulated ProThera products. MultiThera® 1 Capsule Formula is well suited for those who prefer capsules or have difficulty swallowing, as the capsules may be pulled apartand the contents mixed with food if desired. Both iron and copper have been eliminated from this version of MultiThera® to address the needs of patients who may have elevated tissue levels of iron and copper or who do not need to supplement these minerals. MultiThera® 3 is identical in all other respects to MultiThera® 1 tablet formula. Comprehensive micronutrient essentials, iron-free. Vitamin K optional. Iron- and copper-free formula. SUGGESTED USE: 3 capsules twice daily with food. MT1C (No Vitamin K) 180 capsules MT1C-K (Plus Vitamin K) 180 capsules Supplement Facts Serving Size 6 Capsules Amount Per 6 Capsules % Daily Value Vitamin A (67% (5,000 IU) as natural carotenes (alpha, beta, beta-cryptoxanthin, zeaxanthin, and lutein) from D. salina and 33% (2,500 IU) as vitamin A palmitate) Vitamin C (as calcium ascorbate) 7,500 IU 150% 1,000 IU 250% Vitamin E (as d-alpha tocopheryl succinate plus natural 400 IU 1333% mixed tocopherols d-alpha, d-beta, d-delta, d-gamma) from soy 60 mcg Vitamin K (67% as vitamin K1 phytonadione and 33% as vitamin K2 menaquinone-7) MT1C-K ONLY 75% Thiamine (as thiamine hydrochloride USP) 50 mg 3333% Riboflavin (as riboflavin USP) 25 mg 1471% Niacin (75% as niacinamide USP and 25% as niacin USP) Vitamin B6 (as pyridoxine hydrochloride USP) % Daily Value Iodine (from kelp) 150 mcg 100% Magnesium (as magnesium bisglycinate chelate***) 250 mg 63% 15 mg 100% Zinc (as zinc bisglycinate chelate***) 750 mg 1250% Vitamin D3 (as cholecalciferol) Amount Per 6 Capsules 100 mg 500% 25 mg 1250% Selenium (as L-selenomethionine) 200 mcg 286% Copper (as copper bisglycinate chelate***) 2 mg 100% Manganese (as manganese bisglycinate chelate***) 2 mg 100% Chromium (as chromium nicotinate glycinate chelate***) 200 mcg 167% Molybdenum (as molybdenum glycinate chelate***) 150 mcg 200% Potassium (as potassium aspartate) 50 mg 1% Boron (as boron aspartate-citrate) 2 mg * Vanadium (as bisglycinato oxovanadium) 100 mcg * Choline (as choline bitartrate) 100 mg * Folate (as Metafolin®** L-5-methyltetrahydrofolate) 800 mcg 200% Inositol 25 mg * Vitamin B12 (50% as methylcobalamin and 50% as 5-adenosylcobalamin) 200 mcg 3333% para-Aminobenzoic Acid USP 50 mg * * Biotin USP 300 mcg 100% Pantothenic Acid (as d-calcium pantothenate USP) 150 mg 1500% Citrus Bioflavonoids (85 mg as citrus bioflavonoid 100 mg complex, min. 50% bioflavonoids, and 15 mg as hesperidin methylchalcone) Calcium (64% as calcium citrate-malate and 36% as calcium ascorbate) 250 mg 25% Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, silicon dioxide, and natural citrus flavor. *Daily Value not established. **Metafolin® is a registered trademark of Merck KGaA, Darmstadt, Germany ***Albion® Laboratories ® Multiple Vitamin/Mineral Supplement Comparison Selected Ingredient MultiThera® 1 MultiThera® 2 MultiThera® 3 MultiThera® 1 Capsules MultiThera® 1 Capsules Plus K VitaPrime® VitaPrime® Capsules Vitamin A • as retinol 2,500 IU 2,500 IU 2,500 IU 2,500 IU 2,500 IU 2,500 IU 2,500 IU • as natural carotenes 15,000 IU 15,000 IU 15,000 IU 5,000 IU 5,000 IU 3,500 IU 3,500 IU Vitamin C 1,200 mg 1,200 mg 1,200 mg 750 mg 750 mg 250 mg 250 mg Vitamin D3 1,000 IU 1,000 IU 1,000 IU 1,000 IU 1,000 IU 600 IU 600 IU Vitamin E 400 IU 400 IU 400 IU 400 IU 400 IU 150 IU 150 IU Vitamin K 60 mcg 60 mcg 60 mcg ---60 mcg 60 mcg 60 mcg Thiamine 100 mg 100 mg 100 mg 50 mg 50 mg 25 mg 25 mg Niacin 200 mg 200 mg 200 mg 100 mg 100 mg 60 mg 60 mg Pantothenic Acid 400 mg 400 mg 400 mg 150 mg 150 mg 50 mg 50 mg Calcium 500 mg 500 mg 500 mg 250 mg 250 mg 100 mg 50 mg Magnesium 500 mg 500 mg 500 mg 250 mg 250 mg 100 mg 50 mg Iron ---20 mg ---------------Copper 2 mg 2 mg ---2 mg 2 mg 2 mg 2 mg RECOMMENDED USE Intensive support during metabolic disorders, illness, drug therapy, excessive exposure Moderate support to environmental toxins, increased physiological demands, and desire for maximum for routine use and nutritional protection for maintaining healthy life span health maintenance 6 SUGGESTED USE: 3 tablets twice daily with food. Supplement Facts Serving Size 6 Tablets Amount Per 6 Tablets % Daily Value Vitamin A (86% (15,000 IU) as natural 17,500 IU 350% carotenes (alpha, beta, beta-cryptoxanthin, zeaxanthin, and lutein) from D. salina and 14% (2,500 IU) as vitamin A palmitate) Vitamin C (as calcium ascorbate and 1,200 mg 2000% magnesium-potassium ascorbate complex) Vitamin D3 (as cholecalciferol) 1,000 IU 250% Vitamin E (as d-alpha tocopheryl succinate plus 400 IU 1333% natural mixed tocopherols d-alpha, d-beta, d-delta, d-gamma) from soy Vitamin K (67% as vitamin K1 phytonadione and 60 mcg 33% as vitamin K2 menaquinone-7) Thiamine (as thiamine hydrochloride USP) 100 mg Riboflavin (as riboflavin USP) 50 mg Niacin (75% as niacinamide USP and 25% 200 mg as niacin USP) Vitamin B6 (as pyridoxine hydrochloride USP) 50 mg Folate (as Metafolin®** L-5-methyltetrahydrofolate) 800 mcg Vitamin B12 (50% as methylcobalamin and 200 mcg 50% as 5-adenosylcobalamin) Biotin USP 300 mcg Pantothenic Acid (as d-calcium pantothenate USP) 400 mg Calcium (76% as calcium citrate-malate and 500 mg 24% as calcium ascorbate) Iodine (from kelp) 150 mcg Magnesium (75% as magnesium aspartate500 mg ascorbate complex and 25% as magnesium bisglycinate chelate***) Zinc (as zinc bisglycinate chelate***) 20 mg Selenium (as L-selenomethionine) 200 mcg Manganese (as manganese bisglycinate chelate***) 2 mg Chromium (as chromium nicotinate 200 mcg glycinate chelate***) Molybdenum (as molybdenum glycinate chelate***) 150 mcg Potassium (as potassium ascorbate-aspartate complex) 99 mg 75% 6667% 2941% 1000% 2500% 200% 3333% 100% 4000% 50% 100% 125% 133% 286% 100% 167% 200% 3% Boron (as boron aspartate-citrate) 2 mg Vanadium (as bisglycinato oxovanadium) 100 mcg Choline (as choline bitartrate) 150 mg Inositol 50 mg para-Aminobenzoic Acid USP 50 mg Citrus Bioflavonoids (85 mg as citrus bioflavonoid 100 mg complex, min. 50% bioflavonoids, and 15 mg as hesperidin methylchalcone) * * * * * * *Daily Value not established. Other ingredients: Carboxymethylcellulose sodium, cellulose, silicon dioxide, vegetable stearine, vegetable gum, magnesium stearate, natural citrus flavor, and cellulose coating. **Metafolin® is a registered trademark of Merck KGaA, Darmstadt, Germany ***Albion® Laboratories ® MT3 180 tablets Also Available From Klaire Labs® VitaSpectrum™ Multinutrient formula for children on the autism spectrum. Powder or capsules. K-VTS 5.8 oz. (165 g) powder (citrus flavor) K-VTS-BP 5.8 oz. (165 g) powder (berry-pomegranate flavor) K-VTSC 180 vegetarian capsules To request a Klaire Labs® catalog call 888-488-2488. Multiple Vitamin/Mineral Supplements OUR MULTIPLES AT A GLANCE Any one of our multiple vitamin/mineral formulas can be used as a core foundation of essential nutrients for daily use. The appropriate choice for any given patient depends on individual nutrient needs and preferences. It is important to balance need for higher potencies versus patient compliance and cost in making this selection. MultiThera® 1, 2 and 3. Highest potency. With or without iron or copper. These maximum-strength formulas combine significantly higher amounts of essential B-vitamins, antioxidants, and minerals than our other multiples. Calcium and magnesium are included at 500 mg each. Because of these potent amounts, six tablets daily are needed to deliver the full formula. NEW, CAPSULE OPTION! Two-per-day multiple. Iron-free. VitaPrime ® This moderate potency multiple vitamin/mineral/trace element supplement is provided in just two tablets or capsules daily, yet provides significant amounts of essential nutrients in wellutilized forms. It is ideal as a convenient daily insurance formula and a good alternative for patients who cannot or are reluctant to take the recommended six daily tablets or capsules of our more comprehensive MultiThera® formulas. VitaPrime® utilizes similar nutrient sources as MultiThera® formulas to maintain efficient bioavailability, but contains reduced amounts of calcium and magnesium and several other nutrients. Activated forms of folate and vitamin B12 are included along with efficiently utilized mineral forms and fat-soluble vitamins. Compared to common, over-thecounter multivitamin products delivered in one tablet daily, VitaPrime® offers enhanced antioxidant protection, broader trace element nutrition, and augmented B-vitamin support. This core foundation of essential nutrients thus provides an extra measure of nutritional protection that can be recommended for routine daily use. SUGGESTED USE: 1 tablet or capsule twice daily with food. VitaPrime® Tablet Formula Supplement Facts MultiThera® 1 Capsule Formula. Serving Size 2 Tablets High-potency. Iron-free. Vitamin K optional. This formula is a high potency product similar to MultiThera® tablets. However, slight reductions in vitamin C, B-vitamins, and calcium and magnesium (250 mg each) were necessary to fit the formula into six capsules daily, a decision based on maintaining patient compliance. Amount Per 2 Tablets VitaPrime . ® Moderate-potency. Without iron. Designed to fit into just two tablets or capsules daily, VitaPrime® is more potent than most one-pill multiples and uses the same high quality ingredients as MultiThera®. % Daily Value Vitamin A (58% (3,500 IU) as natural 6,000 IU 120% carotenes (alpha, beta, beta-cryptoxanthin, zeaxanthin, and lutein) from D. salina and 42% (2,500 IU) as vitamin A palmitate) Vitamin C (as L-ascorbic acid) 250 mg 417% Vitamin D3 (as cholecalciferol) 600 IU 150% Vitamin E (as d-alpha tocopheryl succinate plus natural 150 IU 500% mixed tocopherols d-alpha, d-beta, d-delta, d-gamma) from soy Vitamin K1 (as phytonadione) 60 mcg 75% Thiamine (as thiamine hydrochloride USP) 25 mg 1667% Riboflavin (as riboflavin USP) 15 mg 882% Niacin (67% as niacinamide USP and 33% 60 mg 300% as niacin USP) Vitamin B6 (as pyridoxine hydrochloride USP) 15 mg 750% Folate (as Metafolin®** L-5-methyltetrahydrofolate) 400 mcg 100% Vitamin B12 (50% as methylcobalamin and 50 mcg 833% 50% as 5-adenosylcobalamin) Biotin USP 300 mcg 100% Pantothenic Acid (as d-calcium pantothenate USP) 50 mg 500% Amount Per 2 Tablets Calcium (as calcium citrate-malate) Iodine (from kelp) Magnesium (as magnesium bisglycinate chelate***) Zinc (as zinc bisglycinate chelate***) Selenium (as selenium amino acid complex) Copper (as copper bisglycinate chelate***) Manganese (as manganese bisglycinate chelate***) Chromium (as chromium nicotinate glycinate chelate***) Molybdenum (as molybdenum glycinate chelate***) % Daily Value 100 mg 150 mcg 100 mg 15 mg 200 mcg 2 mg 2 mg 150 mcg 10% 100% 25% 100% 286% 100% 100% 125% 100 mcg 133% Boron (as boron aspartate-citrate) 2 mg Vanadium (as bisglycinato oxovanadium) 50 mcg Choline (as choline bitartrate) 75 mg Inositol 25 mg Citrus Bioflavonoids (85 mg as citrus bioflavonoid 100 mg complex, min. 50% bioflavonoids, and 15 mg as hesperidin methylchalcone) * * * * * *Daily Value not established. VitaPrime Capsule Formula Supplement Facts ® Serving Size 2 Capsules VitaTab Chewable. ® Amount Per 2 Capsules Chewable wafer option. Low iron. Natural flavors and sweeteners and amounts at 100 - 300% of RDA for most vitamins distinguish this from typical chewable vitamins. Order ProThera and Klaire Labs products TOLL-FREE 7:30 AM • 5 PM Pacific time 888-488-2488 % Daily Value Vitamin A (58% (3,500 IU) as natural 6,000 IU 120% carotenes (alpha, beta, beta-cryptoxanthin, zeaxanthin, and lutein) from D. salina and 42% (2,500 IU) as vitamin A palmitate) Vitamin C (as L-ascorbic acid) 250 mg 417% Vitamin D3 (as cholecalciferol) 600 IU 150% Vitamin E (as d-alpha tocopheryl succinate plus natural 150 IU 500% mixed tocopherols d-alpha, d-beta, d-delta, d-gamma) from soy Vitamin K1 (as phytonadione) 60 mcg 75% Thiamine (as thiamine hydrochloride USP) 25 mg 1667% Riboflavin (as riboflavin USP) 15 mg 882% Niacin (67% as niacinamide USP and 33% 60 mg 300% as niacin USP) Vitamin B6 (as pyridoxine hydrochloride USP) 15 mg 750% Folate (as Metafolin®** L-5-methyltetrahydrofolate) 400 mcg 100% Vitamin B12 (50% as methylcobalamin and 50 mcg 833% 50% as 5-adenosylcobalamin) Biotin USP 300 mcg 100% Pantothenic Acid (as d-calcium pantothenate USP) 50 mg 500% Amount Per 2 Capsules Calcium (as calcium citrate-malate) Iodine (from kelp) Magnesium (as magnesium bisglycinate chelate***) Zinc (as zinc bisglycinate chelate***) Selenium (as selenium amino acid complex) Copper (as copper bisglycinate chelate***) Manganese (as manganese bisglycinate chelate***) Chromium (as chromium nicotinate glycinate chelate***) Molybdenum (as molybdenum glycinate chelate***) Boron (as boron aspartate-citrate) Vanadium (as bisglycinato oxovanadium) Choline (as choline bitartrate) Inositol Citrus Bioflavonoids (50 mg as citrus bioflavonoid complex, min. 50% bioflavonoids, and 15 mg as hesperidin methylchalcone) % Daily Value 50 mg 150 mcg 50 mg 15 mg 200 mcg 2 mg 2 mg 150 mcg 5% 100% 13% 100% 286% 100% 100% 125% 100 mcg 133% 2 mg 50 mcg 75 mg 25 mg 65 mg * * * * * *Daily Value not established. Other ingredients: TABLETS: Cellulose, carboxymethylcellulose sodium, silicon dioxide, vegetable stearine, vegetable gum, magnesium stearate, natural citrus flavor, and cellulose coating. CAPSULES: Vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, cellulose, silicon dioxide, and natural citrus flavor. **Metafolin® is a registered trademark of Merck KGaA, Darmstadt, Germany ***Albion® Laboratories VTP 60 tablets VTP1 120 tablets VTPC 60 capsules ® 7 Multiple Vitamin/Mineral Supplements VitalActiv® VitaTab® Chewable Multinutrient support for bariatric surgical patients. Perfect for kids and adults. VitalActiv® is formulated to provide optimum micronutrient support after bariatric surgery. Nutritional deficits are common in pre- and post-surgical bariatric patients. Poor dietary habits and commonly used medications can lead to nutrient inadequacies and compromise successful postoperative outcomes. After weight loss surgery, patients have unique lifetime nutritional needs as a result of altering the gastrointestinal system. Restrictive procedures reduce stomach capacity resulting in a severely restricted diet, food intolerances, and rapid weight loss. Malabsorptive procedures reroute food, bypassing the stomach and a variable portion of the proximal small intestine, the primary site for nutrient absorption. In addition to nutrients for wound healing, patients need to be supplemented with vitamins and minerals they can no longer readily absorb in the amounts needed to stay healthy. VitalActiv® contains well-tolerated, highly bioavailable nutrient forms to maximize absorption and benefit. SUGGESTED USE: 4 capsules daily with food. Serving Size 4 Capsules Amount Per 4 Capsules % Daily Value Vitamin A (50% (3,500 IU) as vitamin A palmitate 7,000 IU 140% and 50% (3,500 IU) as natural carotenes (alpha, beta, beta-cryptoxanthin, zeaxanthin, and lutein) from D. salina) Vitamin C (as L-ascorbic acid USP) 180 mg 300% Vitamin D3 (as cholecalciferol) 1,000 IU 250% Vitamin E (as d-alpha tocopheryl succinate plus natural 90 IU 300% mixed tocopherols d-alpha, d-beta, d-delta, d-gamma) from soy Vitamin K1 (as phytonadione) 80 mcg 100% Thiamine (75% as thiamine hydrochloride 12 mg 800% and 25% as benfotiamine) Riboflavin (69% as riboflavin USP and 5.1 mg 300% 31% as riboflavin 5’-phosphate) Niacin (75% as niacinamide USP and 40 mg 200% 25% as niacin USP) Vitamin B6 (67% as pyridoxine hydrochloride 6 mg 300% and 33% as pyridoxal 5’-phosphate) ® Folate (as Metafolin ** L-5-methyltetrahydrofolate) 800 mcg 200% Vitamin B12 (80% as methylcobalamin and 250 mcg 4167% and 20% as 5-adenosylcobalamin) Biotin USP 600 mcg 200% Pantothenic Acid (as d-calcium pantothenate USP) 20 mg Calcium (as calcium citrate) 100 mg Iron (as Ferrochel® ferrous bisglycinate chelate***) 45 mg Iodine (from potassium iodide and kelp) 150 mcg Magnesium (as magnesium bisglycinate chelate***) 100 mg Zinc (as zinc bisglycinate chelate***) 15 mg Selenium (as selenium amino acid complex) 70 mcg Copper (as copper bisgluconate) 2 mg Manganese (as manganese bisglycinate chelate***) 2 mg Chromium (as chromium nicotinate 120 mcg glycinate chelate***) Molybdenum (as molybdenum glycinate chelate***) 75 mcg Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), cellulose, L-leucine, and silicon dioxide. **Metafolin® is a registered trademark of Merck KGaA, Darmstadt, Germany ***Albion® Laboratories Patient Inform Ei DHA of EPA and amounts super-concentrates g -strength for lies extra llation processin ent and allow nt supp acid cont cular disti suppleme fatty acid Advanced mole omega-3 fatty omega-3 . fish oil. over 70% serum entrated -purified oil to provide softgel capsules conc ulate ly ultra le fish This high s derived from ber of onses, mod , many peop DHA fromthe fewest num ever fits. atory resp fatty acid of EPA and inflamm e functions. 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Ubiquinone the intestine or antioxidanable for use, how s? by the smal all as formulatio g absorption by .2 After absorption 10, almost E now avail person’s health need .2 In ROL CoQ AL either durin use in the body chylomicrons, into the circulation into to meet a CHAIN one CHEMIC for NSPORT AND BIO quin available poration into the lymphatics are incorporatedal and ON TRA two parts: a , UCTURE and incor is transported via uinone CoQ10 stream. Anim and THE STR IN THE ELECTR made up of units as a side chain l, ubiquino ubiquinol and ubiq reenter the bloodrapidly absorbed as substance isoprenoid te pathway. OF CoQ10 is ring, mevalona a lipophilic and 10 the liver, LDL particles and uinol CoQ10 is about twicehave CoQ10 is d from tyrosine A through the on the quinone been ubiq VLDL and es show that l CoQ 10 both appear to uino synthesize d from acetyl-Cohydroxyl groups xyl groups have studi Ubiq 4 and le. human synthesizel CoQ10 has two the two hydro bioavailab uinone CoQ 10 highly Ubiquino ubiquinone CoQ10 le as ubiq of the bioavailab e half-lives. function while in ketone groups. proper to oxidative comparabl oxidized .COM ent in the5 It cycles between uction . prod tial nutri THERAINC ron port chain an essen WWW.PRO ents for ATP FREE • CoQ10 is drial electron transuce proton gradi dria. In the elect 2488 TOLL s to prod in the mitochon mitochon • 888 488 ctive form 8810 FAX and redu ces free radicals • 775 850 MAIN redu 8800 and 775 850 LE 10439 DOUB 8 . R BLVD , • RENO NV 89521 • Boron (as boron aspartate-citrate) Vanadium (as bisglycinato oxovanadium) Choline (as choline bitartrate) Inositol 2 50 10 25 mg mcg mg mg *Daily Value not established. ® 200% 10% 250% 100% 25% 100% 100% 100% 100% 100% 100% * * * * % Daily Value Calories 10 Total Carbohydrates 3g Sugars 3g Vitamin A (56% (2,500 IU) as natural 4,500 IU carotenes (alpha, beta, beta-cryptoxanthin, zeaxanthin, and lutein) from D. salina and 44% (2,000 IU) as vitamin A palmitate) Vitamin C (as L-ascorbic acid) 180 mg Vitamin D3 (as cholecalciferol) 1,000 IU Vitamin E (as d-alpha tocopheryl succinate plus 90 IU natural mixed tocopherols d-alpha, d-beta, d-delta, d-gamma) from soy Vitamin K1 (as phytonadione) 80 mcg Thiamine (as thiamine mononitrate) 3 mg Riboflavin 3.4 mg Niacin (as niacinamide) 20 mg Vitamin B6 (as pyridoxine hydrochloride) 4 mg Folate (as Metafolin®** L-5-methyltetrahydrofolate) 400 mcg Vitamin B12 (50% as methylcobalamin and 12 mcg 50% as 5-adenosylcobalamin) Biotin USP 300 mcg Pantothenic Acid (as d-calcium pantothenate USP) 20 mg Calcium (as calcium citrate) 100 mg Iron (as carbonyl iron) 4 mg Iodine (from potassium iodide and kelp) 150 mcg Magnesium (as magnesium citrate-ascorbate complex) 100 mg Zinc (as zinc bisglycinate chelate***) 5 mg Selenium (as selenium amino acid complex) 70 mcg Copper (as copper bisgluconate) 0.5 mg Manganese (as manganese bisglycinate chelate***) 2 mg Chromium (as chromium nicotinate 120 mcg glycinate chelate***) Molybdenum (as molybdenum glycinate chelate***) 75 mcg Boron (as boron aspartate-citrate) Vanadium (as bisglycinato oxovanadium) Choline (as choline bitartrate) ation ® cosamax Supplement Facts Amount Per 2 Tablets Supplement Facts % Daily Value SUGGESTED USE: Children age 4 and over: Chew 2 tablets per day with meals. Adults: Chew 2 tablets, once or twice daily with meals. Serving Size 2 Tablets VAC 120 vegetarian capsules Amount Per 4 Capsules These chewable multi-vitamin and mineral wafers are ideal for children or adults who have a hard time swallowing pills. Two tablets provide three times the RDA for vitamin C and E, twice the RDA for most B-vitamins, and easy-to-absorb minerals. Contains no artificial colors, flavors, or sweetening agents. Samples for taste evaluation provided on request. 1 mg 50 mcg 5 mg 1%† * 90% 300% 250% 300% 100% 200% 200% 100% 200% 100% 200% 100% 200% 10% 22% 100% 25% 33% 100% 25% 100% 100% 100% * * * ProThera Technical Support †Percent Daily Values are based on a 2,000 calorie diet. *Daily Value not established. ProThera offers a variety of complimentary technical materials to facilitate patient education. Technical information is easily accessed at protherainc.com by registered patients and healthcare professionals or can be provided upon request. Other ingredients: Fructose, dextrates, vegetable stearine, silicon dioxide, natural cherry flavor, natural orange flavor, maltodextrin, magnesium stearate, and licorice extract. **Metafolin® is a registered trademark of Merck KGaA, Darmstadt, Germany ***Albion® Laboratories Technical Literature Patient Literature VCW 60 chewable tablets • Product Monographs • Scientific Abstracts • Technical Summaries • Nutrient Protocols • Lab Analysis • Frequently Asked Questions • Patient Brochures • Patient Handouts Need additional technical guidance? When further information is needed or questions regarding a specific product arise, ProThera technical support staff are available to speak with clients directly by calling 888-488-2488. ® B-Complex Vitamins ADVANTAGES OF BIOACTIVE FOLATE vs FOLIC ACID Although folic acid is the common form of folate used for nutritional supplements and food fortification, it needs to be activated to provide nutritional benefit. Folic acid must be converted to tetrahydrofolate by the Folate Metabolism intestines and liver before Folic acid it can be used by cells for critical folate-dependent metabolic reactions. The Dihydrofolate body’s ability to transform folic acid is easily overwhelmed and Tetrahydrofolate unmetabolized folic acid enters the bloodstream and can be taken up by cells. Unmetabolized folic acid 10-formyl-THF is not only biologically useless, it actually inhibits folate-dependent chemical 5,10-Methenyl-THF reactions involving DNA synthesis possibly increasing genetic mutations. 5,10-Methylene-THF Many people have gene mutations that impair their ability to make L-5-MTHF bioactive folates, especially L-5-methyltetrahydrofolate (L-5-MTHF). Up to 25% of people have a genetic variant for the enzyme that reduces their ability to make L-5-MTHF. These people are particularly vulnerable to folate deficiency. Sufficient folate is required for normal blood formation, immune system function, cell division, and homocysteine metabolism which is important to maintaining integrity of the inner lining of blood vessels. ProThera routinely includes L-5-MTHF, a bioactive form of folate in MultiThera®, VitaPrime®, and other formulas to support optimal folate nutrition. Unlike folic acid, this biologically active folate requires no chemical transformation to be used by the body: Metafolin®* L-5-methyltetrahydrofolate (L-5-MTHF): Also known as L-methylfolate, this “premethylated” folate requires no extra steps by the body to be absorbed and enter the circulation. Readily taken up and usable by cells, L-5-MTHF is the predominant folate in circulation and the only folate that crosses the blood brain barrier. L-5-MTHF is essential for the conversion of homocysteine into methionine leading to the synthesis of S-adenosylmethionine, the critical carbon source for the majority of the body’s vital methylation reactions. L-MethylFolate Highly bioavailable folate as Metafolin® L-5-MTHF, 1 mg. Folate deficiencies are common as many individuals do not consume enough folate-rich foods and folate is readily destroyed by cooking or processing. Although typically included in multivitamins, some individuals do not effectively methylate and convert folic acid into its bioactive form thus are still at risk of deficiency. L-5-MTHF, an active, methylated form of folate, requires no additional metabolic steps to be used by the body, thus it is often the preferred choice for women, children, and those with absorption or metabolic defects. L-5-MTHF efficiently supports methylation, DNA biosynthesis, homocysteine metabolism, and nervous system function. Supplement Facts Serving Size 1 Capsule Supplies 1 mg (1,000 mcg) folate per capsule. Amount Per Capsule % Daily Value SUGGESTED USE: 1 capsule daily with food. Folate (as Metafolin®* L-5-methyltetrahydrofolate) 1,000 mcg MTF 60 vegetarian capsules Other ingredients: Cellulose, vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, and silicon dioxide. *Metafolin® is a registered trademark of Merck KGaA, Darmstadt, Germany 250% ® Methyl-B12 Lozenge Active, methylcobalamin form of vitamin B12. Provides 5,000 mcg (5 mg) of vitamin B12 as methylcobalamin, the active form especially useful for supporting neurological function and homocysteine metabolism. These fast-dissolving tablets contain a high concentration of vitamin B12 to bypass normal absorptive mechanisms that rely on intrinsic factor. Studies show that B12 can be absorbed by passive diffusion across intestinal membranes when intake is greatly increased. Methyl-B12 Lozenge is a good choice for those with difficulty absorbing vitamin B12. Supplement Facts Tablets may be dissolved in the mouth or Serving Size 1 Tablet swallowed whole. Scored tablets contain Amount Per Tablet % Daily Value natural cherry flavor and xylitol and mannitol Vitamin B12 (as methylcobalamin) 5,000 mcg 83,333% as natural sweetening agents. SUGGESTED USE: 1 tablet daily with food. SMB12 60 tablets Other ingredients: Xylitol, mannitol, silicon dioxide, L-leucine, vegetable stearine, carboxymethylcellulose sodium, natural cherry flavor, citric acid, and magnesium stearate. Active B12-Folate High-potency, fast-dissolving tablets. A high concentration of vitamin B12 is included to Supplement Facts bypass normal absorptive mechanisms that rely Serving Size 1 Tablet on intrinsic factor. Folate complements actions of Amount Per Tablet % Daily Value B12 for homocysteine methylation and nervous Folate (as Metafolin * L-5-methyl800 mcg 200% tetrahydrofolate) system function. Provides bioactive forms of both 1,000 mcg 16,667% vitamin B12 and folate for highest bioavailability Vitamin B12 (as methylcobalamin) of these important B vitamins. Tablets may be Other ingredients: Mannitol, vegetable stearine, silicon dioxide, dissolved in the mouth or swallowed whole. carboxymethylcellulose sodium, and magnesium stearate. ® SUGGESTED USE: 1 tablet daily with food. ABF 60 tablets *Metafolin® is a registered trademark of Merck KGaA, Darmstadt, Germany ® Active B Trio™ Activated B12, folate, and B6. Other L-5-MTHF-Containing Products Active B Complex™...................... CardioThera™ .............................. Methyl Balance™ ........................ MultiThera® .................................. Thera-B™...................................... VitalActiv® .................................... VitaPrime® .................................... Page 11 Page 19 Page 10 Pages 5-6 Page 10 Page 8 Page 7 Supplies bioactive forms of three essential B-vitamins: vitamin B12, folate, and vitamin B6 in small, easy-toswallow vegetarian capsules. SUGGESTED USE: 1 capsule daily with food. ABT 60 vegetarian capsules Supplement Facts Serving Size 1 Capsule Amount Per Capsule % Daily Value Vitamin B6 (from 41 mg pyridoxal 5’-phosphate) 25 mg Folate (as Metafolin®* L-5-methyltetrahydrofolate) 800 mcg Vitamin B12 (as methylcobalamin) 1250% 200% 1,000 mcg 16,667% Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), cellulose, L-leucine, and silicon dioxide. *Metafolin® is a registered trademark of Merck KGaA, Darmstadt, Germany ® 9 B-Complex Vitamins Thera-B™ Benfotiamine Thera-B™ provides a full-complement of essential B-complex vitamins and related nutrients in high potency amounts. Inclusion of Metafolin®** L-5-methyltetrahydrofolate (L-5-MTHF), a bioactive form of folate, ensures more immediate effects than folic acid on metabolism. As the only form of folate that crosses Facts the blood-brain barrier, Supplement Serving Size 1 Tablet L-5-MTHF is especially Amount Per Tablet % Daily Value useful for supporting Thiamine (as thiamine hydrochloride USP) 50 mg 3333% neurological system Riboflavin (as riboflavin USP) 50 mg 2941% requirements for this Niacin (80% as niacinamide USP 50 mg 250% nutrient. Activated and 20% as niacin USP) vitamin B12 as Vitamin B6 (as pyridoxine hydrochloride USP) 50 mg 2500% methylcobalamin Folate (as Metafolin ** L-5-methyltetrahydrofolate) 400 mcg 100% enhances B12 Vitamin B12 (as methylcobalamin) 100 mcg 1667% absorption and Biotin USP 1,500 mcg 500% bioavailability. Extra Pantothenic Acid (as d-calcium pantothenate USP) 200 mg 2000% amounts of biotin to Choline (as choline bitartrate) 100 mg * augment its role for Inositol 100 mg * nervous system para-Aminobenzoic Acid USP 50 mg * function and glucose metabolism are added *Daily Value not established. ingredients: Cellulose, silicon dioxide, carboxymethylcellulose to this yeast-free formula. Other sodium, stearic acid, magnesium stearate, natural citrus flavor, and Benfotiamine is a fat-soluble form of thiamine (vitamin B1) with high bioavailability. It is especially useful for people needing high levels of thiamine or with impaired absorption of this essential B-vitamin. Oral benfotiamine passively diffuses through the intestinal mucosa and is rapidly converted to active thiamine. Its absorption is much more efficient than water-soluble thiamine which requires active transport. Benfotiamine intake attains higher plasma and tissue thiamine levels and maintains these levels longer than common forms of thiamine. Bioavailability of benfotiamine is up to 3.6 times greater than water-soluble thiamine salts and is associated with a 120-fold greater increase in the levels of metabolically active thiamine diphosphate. Benfotiamine inhibits several pathways involved in glucose-induced vascular damage and neuropathies. Clinical studies show that benfotiamine may be particularly indicated for people with diabetes mellitus, chronic renal insufficiency, and chronic alcoholism to support neurological function and protect against formation of tissue-damaging advanced glycation end products (AGEs). Benfotiamine may also be a preferred choice after bariatric surgery as thiamine deficiency is frequently found in these people due to malabsorption. Lipid-soluble form of thiamine. Vitamin B-complex with activated folate and B12. ® SUGGESTED USE: 1 tablet daily with food. TRB 100 tablets cellulose coating. **Metafolin® is a registered trademark of Merck KGaA, Darmstadt, Germany ® Methyl Balance™ Pantothenic Acid Activated B vitamins plus TMG. Vegetarian capsules, 500 mg. Supplies bioactive forms of four essential B-vitamins plus trimethylglycine (betaine) to synergistically support methylation processes and help maintain normal homocysteine metabolism. Pantothenic acid, an essential B vitamin needed to release energy from carbohydrates, protein, and fat in food, is required for synthesis of adrenal hormones and cholesterol. It is a vital component of coenzyme A which is involved in fatty acid metabolism and important for many enzymatic processes. SUGGESTED USE: 1 capsule daily with food. SUGGESTED USE: 1 capsule daily with food. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), cellulose, L-leucine, and silicon dioxide. Supplement Facts MBA 60 vegetarian capsules Amount Per Capsule Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), cellulose, L-leucine, and silicon dioxide. Serving Size 1 Capsule Amount Per Capsule % Daily Value Vitamin B2 (as riboflavin 5’-phosphate) 30 mg 1765% Vitamin B6 (from 25 mg pyridoxal 5’-phosphate) 15 mg 750% Folate (as Metafolin®** L-5-methyltetrahydrofolate) 800 mcg Betaine (trimethylglycine) PAN 100 vegetarian capsules 200% 1,000 mcg 16667% 600 mg * *Daily Value not established. **Metafolin® is a registered trademark of Merck KGaA, Darmstadt, Germany CardioThera™ .............................. Inositone™ .................................. MigraThera™ .............................. MultiThera® .................................. Niacin-SR .................................... VitalActiv® .................................... VitaPrime® .................................... Also Available From Klaire Labs® P-5-P ® Other B-Vitamin-Containing Products 10 % Daily Value Pantothenic Acid (as d-calcium pantothenate USP) 500 mg 5000% Supplement Facts Vitamin B12 (as methylcobalamin) Serving Size 1 Capsule Page 19 Page 32 Page 32 Pages 5-6 Page 19 Page 8 Page 7 Pyridoxal 5’-phosphate (P5P) form of vitamin B6. Supplies 50 mg P5P yielding 30 mg B6. V910-10 100 vegetarian capsules V910-25 250 vegetarian capsules SUGGESTED USE: 1 capsule daily with food. Supplement Facts Serving Size 1 Capsule Amount Per Capsule Thiamine (as benfotiamine) % Daily Value 150 mg 10000% Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, cellulose, and silicon dioxide. BEN 60 vegetarian capsules Biotin High-potency, 5,000 mcg. A high concentration of biotin is provided for situations requiring aggressive supplementation. Biotin-dependent enzymes are involved in glucose metabolism, fatty acid synthesis, nervous system function, and skin and hair nutrition. Extra biotin can be especially beneficial for diabetic patients, bariatric surgery patients, and others with compromised absorption or higher demand for this B-vitamin. Biotin has no known toxicity and large amounts can be taken safely as any excess is readily excreted in the urine. Provided as small, easy-to-swallow vegetarian capsules. SUGGESTED USE: 1 capsule daily with food. Supplement Facts Serving Size 1 Capsule Vitamin B6 Provides 250 mg as pyridoxine HCl. V604-15 150 vegetarian capsules To request a Klaire Labs® catalog call 888-488-2488. Amount Per Capsule Biotin USP % Daily Value 5,000 mcg 1667% Other ingredients: Cellulose, vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, and silicon dioxide. BTN 90 vegetarian capsules B-Complex Vitamins Antioxidants and Vitamins NEW! Active B Complex™ Vitamin D3 High-potency, activated forms. Activated forms of B complex vitamins are provided for situations requiring maximum absorption or higher demand for B-vitamins. Benfotiamine, the lipid-soluble form of thiamine, is included together with active forms of riboflavin, folate, B12, and B6. Provided as small, easy-to-swallow vegetarian capsules. SUGGESTED USE: 1 capsule daily with food. Supplement Facts Serving Size 1 Capsule Amount Per Capsule % Daily Value Thiamine (as benfotiamine) 50 mg 3333% Riboflavin (as riboflavin 5’-phosphate) 20 mg 1176% Niacin (67% as niacinamide USP and 33% as niacin USP) 60 mg Vitamin B6 (as pyridoxal 5’-phosphate) 20 mg 1000% 300% Folate (as Metafolin®* L-5-methyltetrahydrofolate) 400 mcg 100% Vitamin B12 (50% as methylcobalamin and 50% as 5-adenosylcobalamin) 500 mcg 8333% Biotin USP 300 mcg 100% Pantothenic Acid (as d-calcium pantothenate USP) 50 mg 500% Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, cellulose, silicon dioxide, and natural citrus flavor. *Metafolin® is a registered trademark of Merck KGaA, Darmstadt, Germany ® ABC 60 vegetarian capsules Also Available From Klaire Labs® Micellized Vitamin A A highly concentrated liquid micelle form of vitamin A providing 5,025 IU per drop. V060-01 1 fluid oz. (30 ml) Micellized Vitamin D3 Liquid micelle form; 400 IU per drop. K-MCD 1 fluid oz. (30 ml) Micellized Vitamins ADEK Liquid micelle form of four fat-soluble vitamins. K-MVT 1 fluid oz. (30 ml) Pure-E Provides 400 IU vitamin E activity as d-alpha tocopherol plus mixed tocopherols, with approximately 195 mg of gamma-tocopherol. V105-10 100 softgels To request a Klaire Labs® catalog call 888-488-2488. Two high-potency options: 1,000 IU and 5,000 IU Vitamin D is inadequate in many individuals and daily need appears to be higher than previously thought. Vitamin D’s role in calcium metabolism and bone health is well known. However, it has many other important physiologic roles that are not as well appreciated. Vitamin D receptors are widely distributed in the body, including colon, prostate, breast and ovary, where it acts to inhibit the excessive growth of body cells and tissues and helps cells mature normally. Adequate amounts of vitamin D, an essential, fat-soluble vitamin, come from consistent exposure to sunshine and are difficult to obtain from dietary sources. Postmenopausal women, older individuals, and those with malabsorption, limited sun exposure, or certain illnesses may need higher intakes of vitamin D. Vitamin D3, the naturally-occurring form, is supplied in high-potency amounts for those needing to conveniently augment dietary Supplement Facts intake. Daily vitamin D3 intake of 1,000 to 2,000 Serving Size 1 Capsule units, an amount shown to be safe and effective by Amount Per Capsule 1,000 IU % DV clinical studies, is now advised by many experts. Vitamin D3 (as cholecalciferol) 1,000 IU 250% SUGGESTED USE: 1 capsule daily. 5,000 IU % DV 5,000 IU 1250% VTD 100 vegetarian capsules VTD5 100 vegetarian capsules Other ingredients: Cellulose, vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, and silicon dioxide. Vitamin K2 E-Tocotrienol™ Natural source as MK-7. Vitamin E plus tocotrienols. Recent evidence indicates several important functions for vitamin K beyond its role in blood coagulation, including benefits for bone health and vascular function. Supplies natural vitamin K2, also known as menaquinone-7 (MK-7), which has the longest half-life in the body compared to other forms of vitamin K. This vitamin K2 extract is free of soy protein for maximum tolerance by those sensitive to soy. Vitamin E tocopherols and their tocotrienol cousins act as antioxidants and help maintain cardiovascular health, but through different mechanisms. E-Tocotrienol™ offers the benefits of both. This broad-spectrum mixture provides naturally-occurring isomers (d-alpha, d-beta, d-delta, d-gamma) of tocotrienols and small amounts of natural, mixed tocopherol isomers from rice bran. D-alpha tocopherol content is standardized at 100 IU. in its free, unesterified form. D-alpha, the most active and best-studied isomer of vitamin E, helps stabilize and protect cell membranes and tissues susceptible to oxidation such as the eyes, lungs, arteries, and skin. SUGGESTED USE: 1 capsule daily with food. Supplement Facts Serving Size 1 Capsule Amount Per Capsule Vitamin K2 (as menaquinone-7) % Daily Value 50 mcg 63% SUGGESTED USE: 1 to 2 softgels daily with food. Other ingredients: Cellulose, vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, and silicon dioxide. Supplement Facts VK2 60 vegetarian capsules Serving Size 1 Softgel Amount Per Softgel Vitamin E (as d-alpha tocopherol) from soy Vitamin A % Daily Value 100 IU Mixed Tocotrienols (from rice bran oil concentrate) 50 mg** 333% * *Daily Value not established. High-potency 25,000 IU Natural, preformed retinol from fish liver oil. SUGGESTED USE: 1 softgel daily with food. Other ingredients: Gelatin, glycerin, and water. **Elemental tocotrienol content. ETO 60 softgels Supplement Facts Serving Size 1 Softgel Amount Per Softgel Vitamin A (from fish liver oil) % Daily Value 25,000 IU 500% Other ingredients: Soybean oil, gelatin, glycerin, and water. Order ProThera and Klaire Labs products VTA 100 softgels TOLL-FREE 7:30 AM • 5 PM Pacific time 888-488-2488 11 Vitamin Antioxidants C / Flavonoid and Vitamins Antioxidants Resveragen™ Vitamin C Supplies concentrated amounts of resveratrol. Resveratrol is a polyphenolic compound with antioxidant activity found in grapes, wine, blueberries, cranberries, and peanuts. While red wine has been popularized as an important source of resveratrol, amounts vary widely. The maximum content of resveratrol in red wine extracts available for use in dietary supplements is 20%. In contrast, root extracts of Japanese Knotweed (Polygonum cuspidatum) provide up to 50% transresveratrol content, the same Supplement Facts form as found in red wine. Serving Size 1 Capsule Resveragen™ provides 250 mg Amount Per Capsule of trans-resveratrol from Japanese Knotweed (Polygonum cuspidatum), 500 mg* root, dried extract, min. 50% resveratrol) Polygonum cuspidatum root. SUGGESTED USE: 1 to 2 capsules daily with food. *Daily Value not established. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, cellulose, and silicon dioxide. RES 60 vegetarian capsules CitriFlavone™ Citrus bioflavonoids help protect blood vessels and capillaries. Although citrus fruits are best known as excellent sources of vitamin C, they are also exceptional sources of protective antioxidant bioflavonoids that confer numerous health benefits. Citrus peels contain specific flavonoids called flavanones, flavonols, and polymethoxyflavones and include hesperidin, eriodictyol, tangeretin, nobiletin, naringenin, quercetin, and other compounds. By strengthening blood vessel walls, citrus bioflavonoids can support the blood vessels and lymph system. Maintaining structural integrity of capillaries is especially important for those susceptible to hemorrhoids, chronic venous insufficiency, leg ulcers, easy bruising, and nosebleeds. Other actions appear to include a protective effect against inflammation and a role in cholesterol metabolism. CitriFlavone™ contains a concentrated mixture of naturally-occurring flavonoid compounds obtained from a wide array of citrus fruits, including orange, lemon, lime, and Supplement Facts tangerine. Quercetin, Serving Size 1 Tablet a strong antioxidant Amount Per Tablet that prevents oxidation Citrus Bioflavonoid Complex, 600 mg* of low density min. 50% bioflavonoids Hesperidin Methylchalcone 50 mg* lipoproteins, and the Quercetin 100 mg* flavonoid rutin, are Rutin 50 mg* added to enhance the activity of this formula. *Daily Value not established. SUGGESTED USE: 1 to 2 tablets daily with food. CIT 100 tablets Lutein Other ingredients: Cellulose, silicon dioxide, stearic acid, carboxymethylcellulose sodium, magnesium stearate, vegetable gum, and cellulose coating. Protects visual tissues, 6 mg. Multi-Element Buffered C Natural-source FloraGLO®** brand lutein, 6 mg. This vitamin C product contains minerals and trace elements creating a buffered product that is gentle on the stomach. Also contains quercetin. Capsule and powder options. V120-26 Powder 8.8 oz. (250 g) V121-10 100 vegetarian capsules V121-25 250 vegetarian capsules Supplement Facts Serving Size 1 Softgel Amount Per Softgel Lutein (from FloraGLO®** purified marigold flower extract) 6 mg* *Daily Value not established. Other ingredients: Safflower oil, gelatin, glycerin, water, yellow beeswax, and vitamin E mixed tocopherols (from soy). **FloraGLO® is a registered trademark of Kemin Industries, Inc. LUT 90 softgels Vitamin C Powder Ultra-fine, pure ascorbic acid powder providing 1,000 mg per 1/4 teaspoon. V701-26 Powder 8.8 oz. (250 g) To request a Klaire Labs® catalog call 888-488-2488. 12 Individual need for extra vitamin C is quite variable and these 1,000 mg tablets supply pure, crystalline L-ascorbic acid, free of corn antigen, in a convenient and affordable form. A water-soluble cellulose coating protects vitamin C from oxidation and allows for rapid tablet disintegration. SUGGESTED USE: 1 tablet daily with food. Supplement Facts Serving Size 1 Tablet Amount Per Tablet Vitamin C (as L-ascorbic acid) % Daily Value 1,000 mg 1667% Other ingredients: Silicon dioxide, cellulose, stearic acid, magnesium stearate, carboxymethylcellulose sodium, and cellulose coating. VTC1 100 tablets VTC2 250 tablets Ester-C® Buffered C. A non-acidic form of vitamin C that is gentle on the stomach. Created by a unique process resulting in a patented mixture of calcium ascorbate and vitamin C metabolites. SUGGESTED USE: 1 to 2 capsules daily with food. Supplement Facts Serving Size 1 Capsule Amount Per Capsule % Daily Value Vitamin C (as Ester-C®* calcium ascorbate) 500 mg 833% Calcium (from Ester-C®* calcium ascorbate) 62 mg 6% Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, cellulose, and silicon dioxide. *Ester-C® and the Ester-C® logo are licensed trademarks of the Ester-C® Company. ETC 100 vegetarian capsules Ester-C® Bio Buffered C with bioflavonoids. Bioflavonoids complement the action of the Ester-C® calcium ascorbate in this formula. Also Available From Klaire Labs® SUGGESTED USE: 1 softgel daily with food. Pure, unbuffered vitamin C. SUGGESTED USE: 1 to 2 capsules daily with food. Supplement Facts Serving Size 1 Capsule Amount Per Capsule % Daily Value Vitamin C (as Ester-C®** calcium ascorbate) 540 mg 900% Calcium (from Ester-C®** calcium ascorbate) 65 mg 7% Citrus Bioflavonoid Complex 50 mg * Rutin 75 mg * Pycnogenol® Pine Bark (Pinus maritima), dried extract*** 3 mg * *Daily Value not established. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, cellulose, and silicon dioxide. **Ester-C® and the Ester-C® logo are licensed trademarks of the Ester-C® Company. ***Pycnogenol® is a registered trademark of Horphag Research Ltd. Use of this product may be protected by one or more U.S. Patents and other international patents. ETCB 100 vegetarian capsules Flavonoid Antioxidants Potent, Protective Actions Flavonoids, also known as bioflavonoids, are a diverse group of structurally similar plant compounds with extremely valuable antioxidant activity and other important biochemical functions. Although there are thousands of flavonoids, relatively few have been studied in detail. Found in most plant foods, such as grapes, berries, citrus fruit, tea leaves, and even chocolate, flavonoids are responsible for many of the healthy benefits attributed to herbal extracts such as pine bark, ginkgo, hawthorn, and green tea. We have incorporated flavonoid-containing botanicals with documented benefits in a number of ProThera products throughout this catalog to focus their actions for specific patient needs. Grape Extract Full-spectrum concentrate. The complete biological and antioxidant activity of red grapes is retained in this whole grape extract (seeds, skin, and stems) yielding oligomeric proanthocyanidins (OPC), procyanidin dimers, resveratrol, and other active components. SUGGESTED USE: 1 to 4 tablets daily with food. Supplement Facts Serving Size 1 Tablet TheraFlavone™ A concentrated multiflavonoid supplement with diverse benefit, at an affordable price. There are so many useful flavonoid-rich plant extracts, that it can be difficult and costly to take them individually when a balanced and broad-based protective approach is desired. TheraFlavone™ is specifically formulated to provide a wide selection of different types of flavonoids using well-known botanical extracts with well-documented biochemical actions. Only full-spectrum extracts, not isolated flavonoids are included, thus preserving the synergistic activity of all naturally-occurring phytonutrient compounds. TheraFlavone™ is a potent formula providing support for immune function, circulatory health, liver detoxification mechanisms, and antioxidant pathways. Two capsules are equivalent to 10 to 12 tablets or capsules of individual extracts taken separately, resulting in significant cost savings. TheraFlavone™ combines the following full-spectrum plant extracts in one convenient product: • Pycnogenol® Pine Bark Extract – Unique, patented extract from Horphag Research supplying proanthocyanidins and organic acids. • Red Grape Extract – Prepared from the whole grape, not just the seeds, supplying proanthocyanidins, resveratrol, and other beneficial compounds. • Bilberry Extract – Standardized to 25% anthocyanosides and Amount Per Tablet Red Grape (Vitis vinifera) seeds, skin, and stems, dried extract with resveratrol 50 mg* providing as much active flavonoid per capsule as one bilberry capsule taken separately. • Green Tea Extract – A rich source of polyphenols, *Daily Value not established. Other ingredients: Cellulose, stearic acid, silicon dioxide, magnesium stearate, carboxymethylcellulose sodium, and cellulose coating. GRP6 60 scored tablets standardized to 50% catechins for reliable activity. Each capsule equivalent to one cup of green tea. • Ginkgo Extract – A premium 24% extract containing less than 1% ginkgolic acid, an undesirable component, thus exceeding German Commission E specifications. Pycnogenol ® Pine bark extract. This premium French maritime pine bark extract contains numerous bioactive compounds that support capillary and connective tissue function and provide antioxidant protection. SUGGESTED USE: 1 to 4 capsules daily with food. Supplement Facts Serving Size 1 Capsule • Milk Thistle Extract – Supplies guaranteed amounts of silymarin, a hepato-protective flavonolignan. • Citrus Bioflavonoid Complex – Concentrated source of hesperidin, naringen, and other flavonoids from citrus fruit peel. Free of citric acid for best tolerance. SUGGESTED USE: 1 capsule twice daily with food. Amount Per Capsule Pycnogenol® Pine Bark (Pinus maritima), dried extract** 50 mg* *Daily Value not established. Other ingredients: Cellulose, vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, and silicon dioxide. **Pycnogenol® is a registered trademark of Horphag Research Ltd. Use of this product may be protected by one or more U.S. Patents and other international patents. PYC6 60 vegetarian capsules TOLL-FREE 888-488-2488 Amount Per Capsule Pycnogenol® Pine Bark (Pinus maritima), dried extract** Red Grape (Vitis vinifera) seeds, skin, and stems, dried extract with resveratrol Bilberry (Vaccinium myrtillus) fruit, dried extract, min. 25% anthocyanosides Green Tea (Camellia sinensis) leaf, dried extract, min. 50% catechins (polyphenols) Ginkgo (Ginkgo biloba) leaf, dried extract, min. 24% ginkgo flavone glycosides and min. 6% terpene lactones Milk Thistle (Silybum marianum) fruit, dried extract, min. 80% silymarin Citrus Bioflavonoid Complex, min. 50% bioflavonoids 5 mg* 100 mg* 60 mg* 180 mg* 40 mg* 100 mg* 125 mg* *Daily Value not established. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), cellulose, silicon dioxide, and magnesium stearate. **Pycnogenol® is a registered trademark of Horphag Research Ltd. Use of this product may be protected by one or more U.S. Patents and other international patents. THERAFLAVONE’S PHYTONUTRIENT ACTIONS Pycnogenol® Bilberry Extract 7:30 AM • 5 PM Pacific time Serving Size 1 Capsule TFV 60 vegetarian capsules Red Grape Extract Order ProThera and Klaire Labs products Supplement Facts Green Tea Extract Ginkgo Extract Milk Thistle Extract Citrus Bioflavonoids Potent scavenger of free radicals involved in inflammatory processes; supports elasticity and integrity of collagen in joints, capillaries, blood vessels, and skin. Potent scavenger of free radicals involved in inflammatory processes; supports elasticity and integrity of collagen in joints, capillaries, blood vessels, and skin. Antioxidant protection for retina; supports capillary stability and blood flow especially to the eyes. Supports immune responsiveness; counteracts lipid peroxidation. Regulates capillary and cerebral microcirculation; free radical scavenger; supports platelet function. Supports liver function through antioxidant protection and stimulation of glutathione production. Supports lipid metabolism, vascular resiliency, and hepatic enzyme function. 13 Ocular Health Glucose Metabolism OcuThera™ D-Chiro-Inositol Extra antioxidant protection for the eyes. Visual tissues are highly susceptible to free radical damage induced by daily exposure to light radiation and oxygen. Maintaining a strong antioxidant defense system to protect the ocular lens, retina, and macula is critical to maintaining visual health and function. MultiThera® high-potency multiple vitamin/mineral supplements can offer significant daily support for visual function by providing vitamin E, zinc, and other protective antioxidant nutrients. Patients at higher risk of oxidative damage may further benefit from a more specialized approach. OcuThera™ complements the actions of MultiThera® with key amino acids, antioxidants, and phytonutrients that protect and nourish optical tissues. Significant amounts of Supplement Facts Serving Size 2 Capsules lutein, taurine, N-acetylAmount Per 2 Capsules % Daily Value L-cysteine, and other key Vitamin C (as L-ascorbic acid USP) 250 mg 417% nutrients for the eyes are Vitamin E (as d-alpha-tocopheryl succinate) 200 IU 667% provided in just two daily from soy capsules of OcuThera™ Lutein**** 15 mg** * at an affordable price. Zeaxanthin 900 mcg*** * Extra vitamin E and C to N-Acetyl-L-Cysteine USP 300 mg * boost the amounts in L-Glutathione (reduced) 50 mg * MultiThera® are also Alpha-Lipoic Acid 50 mg * included, since high Taurine USP 300 mg * levels appear necessary Bilberry (Vaccinium myrtillus) fruit, dried extract, 60 mg * min. 25% anthocyanosides for protecting lens Red Grape (Vitis vinifera) seeds, skin, 50 mg * proteins from oxidation. and stems, dried extract with resveratrol SUGGESTED USE: 2 capsules daily with food. *Daily Value not established. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), cellulose, L-leucine, silicon dioxide, and natural citrus flavor. **Elemental lutein content ***Elemental zeaxanthin content ****FloraGLO® brand lutein. FloraGLO® is a registered trademark of Kemin Industries, Inc. OCU 60 vegetarian capsules Glutathione Protection Glutathiol™ N-Acetyl-L-Cysteine Triple sulfur antioxidant protection. Glutathione precursor. Glutathiol™ provides three natural sulfurcontaining compounds important to the body’s antioxidant defense mechanisms. N-acetyl-L-cysteine is a valuable precursor for intracellular glutathione production. L-glutathione, a tripeptide containing L-cysteine, L-glutamic acid, and glycine, provides extracellular antioxidant action. The amino acid taurine is a cell membrane stabilizer found in high amounts in heart, skeletal muscle, brain, and retina. SUGGESTED USE: 1 to 2 capsules daily with food. It is recommended that this product be taken with a multiple vitamin and mineral supplement. Serving Size 1 Capsule Amount Per Capsule Vitamin C (as L-ascorbic acid USP) SUGGESTED USE: 1 to 2 capsules daily. % Daily Value SUGGESTED USE: 1 capsule twice daily with food. Supplement Facts Amount Per Capsule D-Chiro-Inositol** Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), cellulose, L-leucine, and silicon dioxide. **Chirositol™ brand, a trademark of Cyvex Nutrition, Inc. Serving Size 1 Capsule Amount Per Capsule 500 mg* *Daily Value not established. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), cellulose, L-leucine, and silicon dioxide. Berberine NEW! Supports healthy glucose regulation. Studies with berberine in people with diabetes show that it exerts multiple beneficial effects on glucose and lipid metabolism. Naturallyderived berberine is provided as berberine hydrochloride, the best studied form. SUGGESTED USE: 1 to 2 capsules daily. 10 mg 17% N-Acetyl-L-Cysteine USP 300 mg * Supplement Facts L-Glutathione (reduced) Taurine USP 50 mg 500 mg * * Serving Size 1 Capsule Amount Per Capsule *Daily Value not established. Berberine hydrochloride Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), cellulose, L-leucine, and silicon dioxide. *Daily Value not established. GSH 60 vegetarian capsules 150 mg* *Daily Value not established. DCH 60 vegetarian capsules Supplement Facts NAC 90 vegetarian capsules Supplement Facts This stereoisomer of inositol is a critical second messenger mediating cellular responses to insulin. Embedded in cell membranes, Dchiro-inositol is part of a glycosyl phosphatidylinositol complex that is hydrolyzed into two bioactive molecules upon exposure to insulin. These molecules regulate glucose disposal by activating pathways in which glucose is either converted to glycogen for storage or oxidatively metabolized to produce energy. Studies show Dchiro-inositol is involved in proper insulin and glucose metabolism and may have a role in maintaining normal lipid profiles, cardiovascular function, and ovarian function. It may also help regulate inflammatory stress and modulate serotonin activity. Although dietary inositol can be converted into D-chiro-inositol in healthy people, insulin-sensitive tissues of Type II diabetics and others may fail to make this conversion. Supplemental D-chiro-inositol has been shown to be bioavailable and improve insulin sensitivity and glucose regulation. Naturally derived from carob pods, D-Chiro-Inositol is recommended to support normal insulin function and protect against the harmful effects of sustained hyperglycemia. Serving Size 1 Capsule This derivative of the amino acid cysteine is often used as the preferred substrate for intracellular glutathione synthesis. It also assists detoxification, provides cellular antioxidant protection, and is much safer than cysteine. N-Acetyl-L-Cysteine USP Supports insulin function and glucose regulation. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), cellulose, L-leucine, and silicon dioxide. BER 60 vegetarian capsules 14 500 mg* Glucose Metabolism Alpha-Lipoic Acid GlucoThera™ A highly versatile antioxidant. This water- and lipid-soluble antioxidant uniquely provides intra- and extracellular protection throughout the body. It also helps regenerate other antioxidants, such as vitamins C, E, and glutathione. And, as a coenzyme for energy production, alpha-lipoic acid helps transport blood glucose into the cell, thus promoting normal blood sugar balance. Internal production of alpha-lipoic acid may be insufficient in those with diabetes, liver conditions, and high exposure to toxins. Each tablet is scored for convenience in adjusting the amount taken. SUGGESTED USE: 1 tablet daily with food. Supplement Facts Serving Size 1 Tablet Amount Per Tablet Alpha-Lipoic Acid 100 mg* *Daily Value not established. Formulated for the special nutritional needs of patients with diabetes and impaired glucose tolerance. Diabetics and others with impaired glucose tolerance are highly susceptible to the tissue-damaging effects of advanced protein glycation, a process that occurs when sugar reacts with body proteins resulting in accumulated destructive effects on blood vessels, nerves, and the lens of the eye. To minimize the potential for such reactions and provide focused support for insulin function, Supplement Facts GlucoThera™ supplies a Serving Size 1 Capsule potent mix of nutrients and Amount Per Capsule % Daily Value Biotin USP 1,250 mcg 417% botanicals that efficiently Chromium (50% as chromium 400 mcg 333% support normal glucose polynicotinate** and 50% as chromium metabolism, interrupt the nicotinate glycinate chelate***) glycation process, and Vanadium (as vanadyl sulfate) 500 mcg * provide antioxidant Alpha-Lipoic Acid 150 mg * protection against tissue N-Acetyl-L-Cysteine USP 250 mg * damage. Add to Banaba (Lagerstroemia speciosa L.) leaf, 24 mg * MultiThera® for dried extract, min. 1% corosolic acid Gymnema (Gymnema sylvestre) leaf, dried 200 mg expanded benefit. * extract, min. 25% gymnemic acids Other ingredients: Cellulose, silicon dioxide, magnesium stearate, vegetable stearine, carboxymethylcellulose sodium, and cellulose coating. ALP 60 tablets Cinnamon Extract Bioactive water-soluble extract. Studies suggest a beneficial role of cinnamon in blood sugar, insulin, and cholesterol metabolism. Active water-soluble type-A polymers are retained and potentially harmful compounds in whole cinnamon are removed in this extract. SUGGESTED USE: 1 capsule twice daily with food. Supplement Facts Serving Size 1 Capsule Amount Per Capsule Cinnamon (Cinnamomum burmannii) bark, 125 mg* dried water-soluble extract, containing type-A polymers** *Daily Value not established. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), cellulose, L-leucine, silicon dioxide, and natural citrus flavor. SUGGESTED USE: 1 capsule twice daily with food. **ChromeMate® brand InterHealth N.I. ***Albion® Laboratories GLC 60 vegetarian capsules GlucoThera™ Forté Enhanced with cinnamon, turmeric, and extra alpha-lipoic acid. Supplies all of the nutrients in GlucoThera™ with the addition of cinnamon and turmeric extracts and twice the alpha-lipoic acid. Cinnamon enhances insulin-signaling pathways. Turmeric contains curcumin, a free radical scavenger shown to prevent AGE formation and cross-linking of collagen. Recommended for those needing maximum support. SUGGESTED USE: 2 capsules twice daily with food. Supplement Facts Serving Size 2 Capsules Amount Per Two Capsules Biotin USP % Daily Value 1,250 mcg 417% Chromium (50% as chromium polynicotinate** and 50% as chromium nicotinate glycinate chelate***) 400 mcg 333% Vanadium (as vanadyl sulfate) 500 mcg * Alpha-Lipoic Acid 300 mg * N-Acetyl-L-Cysteine USP 250 mg * 24 mg * Banaba (Lagerstroemia speciosa L.) leaf, dried extract, min. 1% corosolic acid Other ingredients: Cellulose, vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, and silicon dioxide. **Cinnulin PF® brand, Integrity Nutraceuticals. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), cellulose, L-leucine, silicon dioxide, and natural citrus flavor. **ChromeMate® brand InterHealth N.I. ***Albion® Laboratories ****Cinnulin PF® brand, Integrity Nutraceuticals. * CIN 60 vegetarian capsules Cinnamon (Cinnamomum burmannii) bark, dried 125 mg water-soluble extract, containing type-A polymers**** Gymnema (Gymnema sylvestre) leaf, dried 200 mg extract, min. 25% gymnemic acids GLF 120 vegetarian capsules Turmeric (Curcuma longa) root, dried extract, min. 50% curcuminoids * *Daily Value not established. GlucoTheraPack™ Full-spectrum micronutrient support for diabetics. 50 mg *Daily Value not established. COMPLEMENTARY ACTIONS OF GLUCOTHERA™ INGREDIENTS Biotin Supports glucose metabolism and induces enzymes that encourage cellular retention of glucose, thus slowing its release into bloodstream. SUGGESTED USE: 1 packet twice daily with food. Chromium Polynicotinate Promotes formation of Glucose Tolerance Factor (GTF) needed for insulin function and subsequent control of glucose and lipid levels. Each packet contains: 3 MultiThera® 1 Multiple Vitamin/Mineral tablets • 1 GlucoThera™ capsule • 1 Alpha-Lipoic Acid tablet • 1 Marine Fish Oil softgel. Vanadyl Sulfate Encourages normal glucose metabolism by supporting tissue insulin responsiveness. Alpha-Lipoic Acid Assists safe disposal of excess glucose and discourages formation of damaging advanced glycation end-products (AGE). N-Acetyl-L-Cysteine Reduces oxidative stress crucial to controlling AGE formation and inhibiting damage to pancreatic cells. Convenient packets provide intensive nutrient support for glucose and insulin metabolism. GLCP 30 packets GLCP60 60 packets Also available: GlucoThera™ Forté Pack Each packet contains: 3 MultiThera® 1 Multiple Vitamin/Mineral tablets • 2 GlucoThera™ Forté capsules • 1 Marine Fish Oil softgel. GLFP 30 packets GLFP60 60 packets See pages 5, 15, and 26 for full ingredient information. * Banaba Extract Helps maintain normal transport of glucose into cells. Gymnema Extract Assists regeneration and repair of pancreatic beta cells and may reduce intestinal glucose absorption. Cinnamon Extract* Enhances both insulin secretion and intracellular insulin signaling; improves insulin sensitivity and blood glucose metabolism. Turmeric Extract* Assists blood sugar-regulating ability and is highly protective of ocular tissues. *Found only in GlucoThera™ Forté 15 CoEnzyme Q10 PURE, NATURAL COENZYME Q10 ProThera® and Klaire Labs® products contain ultra-pure coenzyme Q10 (CoQ10) in its natural trans isomeric form. Manufactured to precise pharmaceutical-level specifications, pure, trans isomer CoQ10 is the only form supported by over 30 years of clinical trials demonstrating safety and effectiveness. We offer a range of formulation options for flexibility in selecting the appropriate product for each patient. CoEnzyme Q10 A crucial antioxidant in a reliable oil-based delivery system. The heart muscle, periodontal tissues, immune system, liver, kidney, brain, and other vital organs require coenzyme Q10 to supply energy through ATP activation and to help protect them from free radical damage. Illness, aging, poor nutrient intake, and use of certain medications can result in inadequate endogenous production of CoQ10 to sustain optimal organ function. We supply pure coenzyme Q10 as ubiquinone completely solubilized in natural d-limonene oil, derived from citrus oil, and vitamin E in these convenient softgel formulations. This unique solubilization process assists absorption of coenzyme Q10, a fat-soluble nutrient, by ensuring a source of dietary fat is present. Supplement Facts Four potency options of 30, 60, Serving Size 1 Softgel 100, and 200 mg allow for easy Amount Per Softgel % Daily Value dosage adjustment. CoQ10 SUGGESTED USE: 1 to 2 softgels daily with food. 200 mg 100 mg 60 mg 30 mg Vitamin E 200 IU 667% 100 IU 333% 60 IU 200% (as d-alpha tocopherol plus natural mixed tocopherols) from soy 30 IU 100% Coenzyme Q10 200 mg (as ubiquinone) 30 mg * 100 mg * 60 mg * * *Daily Value not established. Other ingredients: D-limonene oil, gelatin, glycerin, medium chain triglycerides, water, turmeric, and zinc oxide. CQ30 (30 mg) 60 softgels CQ60 (60 mg) 60 softgels CQ100 (100 mg) 30 softgels CQ200 (200 mg) 30 softgels Coenzyme Q10 is a fat-soluble nutrient absorbed through the same process as other lipids. Fats are emulsified with the aid of bile salts in the intestines forming micelles that can be absorbed and carried through the lymphatic system into the bloodstream. Absorption of lipophilic nutrients including CoQ10 is improved when consumed with other fats in a meal as solubilization in fat enhances the surface area available for emulsification. Studies show that pure, powder-filled CoQ10 capsules, such as those provided in the Klaire Labs® line, are well absorbed when taken with lipid-containing meals. ProThera® CoQ10 products utilize a variety of natural emulsifiers or oil-based carriers, including vitamin E, lecithin, and d-limonene oil, to facilitate absorption, thus do not require the presence of dietary fats when ingested. CoQH™ Reduced ubiquinol form. Two beneficial forms of CoQ10, ubiquinone and ubiquinol, are continually recycled in the body. Ubiquinol acts as a potent antioxidant in mitochondria and lipid membranes. Sufficient amounts of both forms are needed for efficient ATP production. Normally, ubiquinone is efficiently reduced to ubiquinol during absorption or shortly after entering the bloodstream. However, this ability declines with age and is markedly compromised in certain chronic diseases such as diabetes mellitus. As ubiquinol can be directly utilized by the body, CoQH™ is a good alternative for patients who may have difficulty converting ubiquinone to ubiquinol. Pure ubiquinol is solubilized in d-limonene oil and stabilized with natural emulsifying agents. SUGGESTED USE: 1 to 2 softgels daily with food. Supplement Facts Serving Size 1 Softgel Chewable CoEnzyme Q10 300 mg - Emulsified with lecithin Supplement Facts Also Available From Klaire Labs® Serving Size 1 Tablet Amount Per Tablet % Daily Value Vitamin E (as dl-alpha tocopheryl acetate) 300 IU 1000% Coenzyme Q10 (as ubiquinone) 150 mg * Amount Per Tablet Coenzyme Q10 (as ubiquinone) 300 mg* *Daily Value not established. Other ingredients: Fructose, dextrates, silicon dioxide, natural butterscotch flavoring, calcium silicate, magnesium stearate, and glycyrrhiza. Other ingredients: Dextrates, fructose, silicon dioxide, lecithin from soy, vegetable stearine, natural vanilla flavor, magnesium stearate, and natural maple nut flavor. CONTAINS SOY AND TREE NUTS. CQ150 (150 mg) 30 tablets CQ300 (300 mg) 30 tablets *Daily Value not established. 16 100 mg* CQH (50 mg) 60 softgels CQH1 (100 mg) 60 softgels SUGGESTED USE: Chew 1 to 2 tablets daily. Serving Size 1 Tablet 100 mg 50 mg* Other ingredients: D-limonene oil, gelatin, glycerin, water, caprylic acid, capric acid, natural caramel coloring, and alpha-lipoic acid. **Kaneka QH™ reduced form of coenzyme Q10. Kaneka QH™ is a trademark of Kaneka Corporation. High potency coenzyme Q10 is emulsified with vitamin E or lecithin in a convenient, chewable wafer. Natural sweeteners and flavors and our special manufacturing process make these excellent tasting products. Supplement Facts 50 mg Coenzyme Q10 (as ubiquinol)** *Daily Value not established. Two high potency options. 150 mg - Emulsified with vitamin E Amount Per Softgel CoEnzyme Q10 Vegetarian capsule options providing 60 mg or 100 mg pure ubiquinone per capsule. V020-03 (100 mg) 30 vegetarian caps K-CQ6 (60 mg) 60 vegetarian capsules To request a Klaire Labs® catalog call 888-488-2488. CoEnzyme Q10 Key for Mitochondrial Function and Antioxidant Protection Coenzyme Q10 (CoQ10) is a naturally-occurring compound that is essential for cellular energy production. CoQ10 is a crucial cofactor in the mitochondrial electron transport chain from which adenosine triphosphate (ATP), the body’s primary energy currency, is derived. CoQ10 also protects tissues from free radical damage and supports cardiovascular and neurological function. Mitochondria are organelles often referred to as the “powerhouses” of cells because they convert nutrients into energy using oxygen. Mitochondrial integrity can be compromised by a number of factors including aging, illness, stress, mtDNA mutations, and exposure to environmental toxins. As an integral carrier within the electron transport chain, CoQ10 is needed to produce ATP which makes energy available for innumerable biochemical and physiological processes including chemical synthesis, operation of cellular ion pumps and channels, contraction of muscles, excretion of metabolic wastes, secretion of hormones, and transmission of nerve impulses. Coenzyme Q10 is the only lipid-soluble antioxidant synthesized in the human body. CoQ10 inhibits the oxidation of vital molecules such as DNA, membrane phospholipids, and circulating lipoproteins. CoQ10 also recycles and regenerates other antioxidants such as vitamin E and vitamin C. Advancing age, poor diet, illness, and certain medications can impair the body’s ability to produce CoQ10 and may result in CoQ10 deficiency. It has been well documented that tissue levels of endogenous CoQ10 decrease with age, especially in individuals age 40 or older. ™ MitoThera Focused support for mitochondrial energy production. One of the most overlooked factors underlying the body’s aging process is dysfunction of cellular mitochondria. The ability of mitochondria to sustain the high energy demands of the brain, liver, heart, muscles, endocrine glands, and other tissues can be compromised by many factors, including exposure to toxins, inadequate antioxidant intake, illness, genetic factors, and a decline in cellular function with increasing age. The accumulated effects of oxidative damage can disrupt mitochondrial membranes and damage lipids, DNA, and proteins, resulting in suboptimal functioning of affected organ systems. MitoThera™ supplies key nutrients and energy substrates to protect against free radical damage and assist mitochondria in performing their critical functions most efficiently. Magnesium malate, sodium succinate, coenzyme Q10, creatine monohydrate, and acetyl-L-carnitine each support energy pathways in complementary ways. N-acetyl-L-cysteine, alpha-lipoic acid, grape flavonoids, quercetin, coenzyme Q10, and acetyl-L-carnitine enhance cellular antioxidant defenses. Lecithin in MitoThera™ tablet formula provides phospholipids to help support membrane fluidity. Lecithin is excluded from MitoThera™ capsules for best tolerance TM by patients sensitive to soy. MitoThera Tablet and Capsule Formulas MitoThera™ is an excellent Supplement Facts companion product to Serving Size 3 Tablets or 4 Capsules MultiThera®, VitaPrime®, Amount Per 3 Tablets or 4 Capsules % Daily Value Amount Per 3 Tablets or 4 Capsules or our Klaire Labs® Magnesium 45 mg 11% Quercetin (as magnesium malate) VitaSpectrum™ multiple Red Grape (Vitis vinifera) seeds, skin, and stems, vitamin/mineral supplements Sodium (as sodium succinate) 85 mg 4% dried extract with resveratrol for patients with disorders Coenzyme Q10 (ubiquinone) 50 mg * Sodium Succinate of energy metabolism, Acetyl-L-Carnitine 200 mg * TABLET FORMULA ONLY: (as acetyl-L-carnitine hydrochloride) chronic illnesses, and Lecithin (from soy) N-Acetyl-L-Cysteine USP 100 mg * aging individuals who Phosphatidylcholine 50 mg Alpha-Lipoic Acid 100 mg * need specialized *Daily Value not established. Creatine Monohydrate 200 mg * nutritional support. SUGGESTED USE: 3 tablets or 4 capsules daily with food. Malic Acid (as magnesium malate) 255 mg % Daily Value 125 mg * 25 mg * 300 mg * 125 mg * * * Other ingredients: TABLETS: Cellulose, silicon dioxide, carboxymethylcellulose sodium, stearic acid, magnesium stearate, and cellulose coating. CAPSULES: Vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, cellulose, and silicon dioxide. TABLETS CONTAIN SOY. MTO 90 tablets MTOC 120 vegetarian capsules COMPLEMENTARY ACTIONS OF MITOTHERA™ INGREDIENTS Order ProThera and Klaire Labs products TOLL-FREE 7:30 AM • 5 PM Pacific time Magnesium Facilitates synthesis of ATP; stabilizes mitochondrial membranes. Coenzyme Q10 Serves as crucial cofactor in ATP production; provides antioxidant protection in mitochondria and lipid membranes. Acetyl-L-Carnitine Transports fatty acids into mitochondria of nerve, heart, and muscle cells for use in energy production; supports membrane stability. N-Acetyl-L-Cysteine Supports optimal levels of glutathione in mitochondria; helps preserve mitochondrial function. Alpha-Lipoic Acid Serves as coenzyme for energy production pathways; minimizes oxidative stress. Creatine Monohydrate Helps maintain optimal ATP levels. Malic Acid Functions as component of the Krebs cycle; transports high-energy substrates into the mitochondria. Quercetin Supports antioxidant defenses; may decrease mitochondrial free radical production. Red Grape Extract Provides antioxidant protection; reduces mitochondrial lipid peroxidation. Sodium Succinate Facilitates the reduction of FAD as Krebs cycle intermediate; supports transfer of electrons to the electron transport chain. Supplies phosphatidylcholine that helps maintain membrane fluidity for proper transport of nutrients to and from the cells. Lecithin (Tablet formula only) 888-488-2488 17 Cardiovascular Support D-Ribose Supports heart and skeletal muscle energy metabolism. D-Ribose, a monosaccharide sugar found in all living cells, plays a critical role in cellular metabolic pathways that generate energy. D-Ribose supports normal heart muscle function and may also support normal skeletal muscle function during exercise and in people with certain muscular dystrophies or fibromyalgia. As a fundamental constituent of adenosine triphosphate (ATP), D-ribose is essential for normal energy production. It is also a component of nucleotides, deoxyribonucleic acid (DNA), and ribonucleic acid (RNA). Found in small amounts in the diet, the body must synthesize D-ribose from glucose. Cardiac muscle is especially vulnerable to conditions that deplete ATP and nucleotide pools. It may take days for ATP levels to be restored after strenuous exercise or ischemia as both cardiac and skeletal muscle have low levels of enzymes needed to convert D-ribose to D-ribose-5-phosphate, the activated form of D-ribose that plays a critical role in regenerating cellular ATP. D-Ribose administration has been shown to significantly accelerate restoration of heart ATP levels, especially in the setting of inadequate blood flow to the heart muscle and diminished exercise capacity. Pure D-Ribose is supplied in powder form for convenient supplementation of multi-gram amounts found to be beneficial. D-Ribose powder has a natural, slightly Supplement Facts sweet taste and Serving Size 1 Scoop (Approx. 5 grams) mixes readily in Amount Per Scoop % Daily Value water or juice. Calories 20 SUGGESTED USE: 1 scoop (approx. 5 grams) daily. Mix in water or juice. Take with or between meals. Total Carbohydrates Sugars D-Ribose powder 5g 5g 2%† * 5g * †Percent Daily Values are based on a 2,000 calorie diet. *Daily Value not established. Mag-Potassium Aspartate Cardio-supportive electrolytes. The essential and complementary roles of magnesium and potassium in maintaining normal heart rhythm, blood pressure, and energy production are crucial to health. Complexing with aspartic acid facilitates their cell-energetic properties. SUGGESTED USE: 1 to 2 tablets daily with food. Supplement Facts Serving Size 1 Tablet Amount Per Tablet % Daily Value Magnesium (as magnesium-aspartate complex) 100 mg Potassium (as potassium-aspartate complex) Aspartic Acid (total yield) 25% 99 mg 3% 682 mg * *Daily Value not established. Other ingredients: Cellulose, stearic acid, carboxymethylcellulose sodium, silicon dioxide, magnesium stearate, and cellulose coating. MPA 100 tablets Hawthorn Extract A cardioactive herb. Other ingredients: None. DRB 10.58 oz (300 grams) ™ AntioxTheraPack A potent antioxidant supplement program. The specific combination of nutrients in these convenient packets has been used in clinical practice for many years to support cardiovascular health and immune function through the synergistic action of antioxidants that depend on each other for maximum effectiveness. Antioxidants exert their fullest protective benefits through a series of related actions called the antioxidant cascade. AntioxTheraPack™ supplies significant amounts of key nutritional antioxidants and cofactors that activate antioxidant pathways and help protective cellular mechanisms operate at high efficiency. Studies show hawthorn relaxes coronary vessels and enhances blood flow to the heart, which are key factors in maintaining normal blood pressure. Other positive effects on the heart include antioxidant protection and increased contractile strength. Standardized to vitexin, an active flavonoid component. SUGGESTED USE: 1 to 3 capsules daily. Supplement Facts Serving Size 1 Capsule Amount Per Capsule Hawthorn (Crataegus oxyacantha) leaf and flower dried extract, min. 1.8% vitexin 250 mg* *Daily Value not established. SUGGESTED USE: 1 packet twice daily with meals. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), cellulose, silicon dioxide, and magnesium stearate. Each packet contains: 3 MultiThera® 1 tablets A strong antioxidant foundation, including vitamins C, E, and natural betacarotene; zinc, copper, and manganese to activate superoxide dismutase (SOD); and selenium and B-vitamins to keep glutathione enzymes active. 1 Vitamin C (1,000 mg) tablet Extra ascorbic acid to help regenerate vitamin E. 1 CoEnzyme Q10 (60 mg) softgel Pure CoQ10 with vitamin E (60 IU) in d-limonene oil. 1 Glutathiol™ capsule Sulfur-based antioxidants, glutathione (50 mg), NAC (300 mg), and taurine (500 mg). HAW 60 vegetarian capsules See pages 5, 12, 14, and 16 for full ingredient information. Malic Acid Natural energy substrate. Supplies 500 mg malic acid, used for making ATP, the molecule that provides energy to muscles, brain, heart, and other tissues. SUGGESTED USE: 1 to 2 capsules daily with food. Supplement Facts Serving Size 1 Capsule Amount Per Capsule Malic acid 500 mg* *Daily Value not established. ATP 30 packets Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), cellulose, silicon dioxide, and magnesium stearate. MAL 100 vegetarian capsules 18 Cardiovascular Support Niacin-SR Sustained-release niacin. Slow release of niacin over several hours helps avoid the uncomfortable flushing action of this B-vitamin so that its full benefits on cholesterol metabolism can be obtained. Scored tablet. SUGGESTED USE: 1 tablet daily with food. Supplement Facts Serving Size 1 Tablet Amount Per Tablet % Daily Value Niacin (as niacin USP) 500 mg 2500% Other ingredients: Vegetable stearine, cellulose, silicon dioxide, magnesium stearate, and carboxymethylcellulose sodium. NCN 100 tablets CardioThera™ Lecithin Natural blend of phosphatides. Lecithin is a natural mixture of phosphatides, including phosphatidylcholine, phosphatidylethanolamine, and phosphatidylinositol. Phosphatides are important for structural integrity of every cell in the body and help to maintain membrane fluidity for proper transport of nutrients to and from the cells. Lecithin also plays a role in the breakdown of fats in the diet and participates in signal transduction, which is an essential process for cell growth and function. SUGGESTED USE: 1 to 2 softgels daily. Supplement Facts Serving Size 1 Softgel Amount Per Softgel % Daily Value Calories Calories from Fat Total Fat Saturated Fat Polyunsaturated Fat 10 10 1g 0g 1g High Phosphatide Lecithin (from soy) Supplying phosphatidylcholine, phosphatidylethanolamine, and phosphatidylinositol 1,200 mg 2%† 0%† * * †Percent Daily Values are based on a 2,000 calorie diet. *Daily Value not established. Other ingredients: Gelatin, glycerin, polyglycitol syrup, and water. LEC 100 softgels Targets homocysteine, lipid, and cardiac energy metabolism. CardioThera™ supports cardiovascular function in several ways to address multifactorial issues often seen in clinical practice. Because some patients need a more aggressive approach to nutritional supplementation than a daily vitamin and mineral insurance program, CardioThera™ includes active, bioavailable forms of folate and vitamin B12 plus betaine which act as methyl donors to support the methylation process and help maintain normal homocysteine metabolism. L-carnitine carries fatty acids into the mitochondria Supplement Facts of heart and skeletal muscle cells for use Serving Size 1 Capsule in energy production to help keep the heart Amount Per Capsule % Daily Value working efficiently. Policosanol is a unique plant Folate (as Metafolin ** L-5-methyltetrahydrofolate) 200 mcg 50% extract that supports cholesterol metabolism and Vitamin B12 (as methylcobalamin) 100 mcg 1667% platelet function while the potent antioxidant Betaine (trimethylglycine) 250 mg * resveratrol helps prevent lipid peroxidation, thus L-Carnitine (as L-carnitine tartrate)*** 250 mg * helping to protect cardiovascular tissues from Japanese Knotweed (Polygonum cuspidatum) 2 mg * root dried extract, min. 50% resveratrol oxidative damage. By selecting nutritional 5 mg * compounds that deliver significant benefit using a Policosanol (Saccharum officinarum) dried extract, min. 95% aliphatic alcohols relatively small amount of material, we were able to formulate CardioThera™ into just two capsules *Daily Value not established. ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, daily while providing substantial nutritional support Other water), cellulose, magnesium stearate, and silicon dioxide. for the cardiovascular system in an affordable form. **Metafolin is a registered trademark of ® ® SUGGESTED USE: 1 capsule twice daily with food. CRD 60 vegetarian capsules Merck KGaA, Darmstadt, Germany ***Carnipure® brand, a licensed trademark of Lonza, Ltd. Used under license from Lonza, Ltd. CardioTheraPack™ Policosanol Cardiosupportive nutrient program. Helps maintain normal cholesterol. Four ProThera products that support cardiovascular function in complementary ways are included to address inflammatory mechanisms, homocysteine metabolism, energy pathways, cholesterol and lipid metabolism, regulation of coronary blood flow, and essential nutrient needs. SUGGESTED USE: 1 packet daily with food or as directed by healthcare practitioner. Each packet contains: 3 MultiThera® 1 tablets • 1 CardioThera™ capsule • 1 InflaThera™ capsule • 1 Hawthorn Extract capsule. This natural compound has been shown in more than 15 double-blind controlled clinical trials to maintain normal levels of total, HDL, and LDL cholesterol. It inhibits the oxidation of LDL and has beneficial actions on cardiovascular capacity, platelet function, and eicosanoid balance. Derived from sugar cane wax, policosanol is a mixture of aliphatic alcohols such as L-octacosanol, 1-triacontanol, and others. Studies show between 10 to 40 mg daily of policosanol extract produces benefit. SUGGESTED USE: 1 to 4 capsules daily with food. Order ProThera and Klaire Labs products Supplement Facts TOLL-FREE Amount Per Capsule Serving Size 1 Capsule Policosanol (Saccharum officinarum) dried extract, min. 95% aliphatic alcohols 7:30 AM • 5 PM Pacific time 888-488-2488 ® 10 mg* *Daily Value not established. Other ingredients: Cellulose, vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, and silicon dioxide. CRDP 30 packets See pages 5, 18, 19, and 31 for ingredient information. POL 60 vegetarian capsules 19 Gastrointestinal Support Deparex™ Protectagen™ Protects GI tissue against damage while promoting DNA repair. Inadequate DNA repair ability is closely linked with declining organ system function and poor immune response associated with aging, exposure to toxins, chronic stress, nutrient deficiencies, and disease processes. AC-11®, the active ingredient in Protectagen™, is a patented, water-soluble botanical extract of Uncaria tomentosa shown to uniquely support the body’s natural defenses at the molecular level against oxidative stress, inflammation, infection, and DNA damage. By assisting enzymatic mechanisms that repair DNA, AC-11® helps counteract accumulated cellular damage that can adversely affect metabolic functions critical to the health of the entire body. AC-11® supports cellular resistance to a wide variety of environmental stressors and may be particularly beneficial to support gastrointestinal healing. By protecting GI tissues against damage and promoting DNA repair, Protectagen™ can help restore and maintain normal functioning of the GI system. AC-11® extract may also enhance protective immune responses to invasive microorganisms such as Staphylococcus and Klebsiella species, thus further protecting the GI system. AC-11® is standardized to contain 8-10% carboxyl alkyl esters, compounds responsible for 90% of its bioactivity. Unlike other preparations of Uncaria tomentosa (commonly called cat’s claw), AC-11® is virtually free of potentially immunosuppressive and toxic oxindole alkaloids (TOA’s). AC-11’s carboxyl alkyl and other patent process esters are unencumbered by the Supplement Facts presence of oxindole alkaloids which allows Serving Size 1 Capsule Protectagen™ to exert unique protective and reparative actions not provided by any Amount Per Capsule other cat’s claw product. AC-11®** patented water-soluble extract of SUGGESTED USE: 1 to 2 capsules daily. Uncaria tomentosa, min. 8% carboxy alkyl esters Undecylex™ Deparex™ provides selected ingredients that support a healthy balance of intestinal microbiota. Berberine sulfate provides broadspectrum support against numerous potential pathogens. Artemisia absinthium, also known as wormwood, has been used for thousands of years as a medicinal herb for its bitter properties as a natural repellant, stomachic, and carminative. Artemisia annua, commonly known as sweet wormwood, is rich in a sesquiterpene lactone that serves as a natural defense agent for the plant. Green tea provides polyphenols that hinder microbial growth and activity. May be useful in a broad GI detoxification program or separately to support microbial balance. SUGGESTED USE: 1 capsule twice daily before meals. 350 mg* Supplement Facts Serving Size 1 Capsule *Daily Value not established. PTG 60 vegetarian capsules Botanical formula with Artemisia supports GI microbial balance. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), cellulose, L-leucine, and silicon dioxide. **AC-11® is a trademark of Optigenex Inc. AC-11® is protected by U.S. Patent Numbers 6,039,949, 6,238,675 B1, 6,361,805 B2, 6,964,784 B2, 7,579,023 B2, and 7,595,064 B2. Amount Per Capsule Proprietary Botanical-Berberine Blend 600 mg* Wormwood (Artemisia absinthium) whole plant Sweet Wormwood (Artemisia annua) leaf, dried 30:1 extract Green Tea (Camellia sinensis) leaf, dried extract, min. 40% epigallocatechin gallate, min. 95% polyphenols Berberine Sulfate Natural fatty acids and botanicals help rebalance intestinal microflora. *Daily Value not established. This powerful formula combines specific natural agents that discourage overgrowth of a broad spectrum of yeast, fungi, and other unwanted intestinal microorganisms, thus supporting a healthy balance of intestinal microflora. Berberine, an alkaloid found in various plants, has several metabolic and inhibitory actions that make it a valuable adjunct during microbial infections. Polyphenols in green tea can adversely affect viability of certain microbial pathogens and yeasts. Undecylenic acid provided by calcium Supplement Facts undecylenate is a Serving Size 1 Tablet monounsaturated fatty Amount Per Tablet acid which inhibits Calcium Undecylenate 100 mg* hyphae formation in yeast Sorbic Acid 33 mg* Berberine Sulfate 133 mg* cells while sorbic acid Indian Barberry (Berberis aristata) root bark, dried extract, 57 mg* has well-known inhibitory min. 6% berberine action against bacterial Coptis (Coptis chinensis) root, 17 mg* dried extract, min. 20% berberine contaminants. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, cellulose, and silicon dioxide. Green Tea (Camellia sinensis) leaf, dried extract, min. 80% polyphenols 33 mg* *Daily Value not established. DEP 60 vegetarian capsules SUGGESTED USE: 1 to 6 tablets daily with food. Other ingredients: Cellulose, silicon dioxide, vegetable stearine, stearic acid, carboxymethylcellulose sodium, magnesium stearate, and cellulose coating. UND 120 tablets Order ProThera and Klaire Labs products TOLL-FREE 7:30 AM • 5 PM Pacific time 20 888-488-2488 Gastrointestinal Support Gateway to the Immune System In addition to its digestive and elimination functions, the GI tract is our first line of defense, as it contains 70% of the body’s immune cells. Gut-associated lymphoid tissue (GALT) in the small intestine forms a strong protective barrier against ingested pathogens or antigens from food digestion, yet allows important nutrients to enter the bloodstream. These protective mucosal cells lining the intestinal tract are under constant challenge and can be adversely affected by dietary deficiencies, stress, toxic chemicals, allergens, and pathogenic bacteria or viruses. When normal structure and function of intestinal tissues is compromised, dysfunctions ranging from minor GI discomforts to more severe impairments such as irritable bowel syndrome and inflammatory disorders can compromise overall health in numerous ways. Specific nutrients and probiotics can help maintain normal structure, function, digestive, and immune protective activities of the entire GI system. GastroThera™ Glutamine-rich, prebiotic formula supports GI and immune function. GastroThera™ provides intensive support for the entire GI tract by addressing energy requirements of intestinal mucosa, structural composition of intestinal and colonic cells, microorganism balance, and regulation of protective intestinal mucus secretions. Large amounts of the amino acid glutamine, the primary fuel for intestinal cell function, help meet the high energy demands of the GI tract, liver, and immune system during periods of physiological stress and transport potentially toxic ammonia to the kidneys for excretion. Acacia and inulin add soluble fiber that is readily fermentable into shortchain fatty acids that support growth of beneficial bacteria, assist water absorption, and support colonic cell function. N-Acetyl-D-Glucosamine helps form intestinal mucous secretions that protect intestinal tissues and help food pass through the GI tract. GastroThera™ can be taken regularly or periodically for nutritive support of GI function and is often used with probiotic supplementation. The powder is neutral in taste and readily soluble in water. SUGGESTED USE: Powder Formula: 1 scoop (approx. 6 grams) twice daily. For best results, mix in cold or room temperature water or non-acidic juice and take between meals. Capsule Formula: 6 capsules daily with food or between meals. Supplement Facts Serving Size 1 Scoop (6 grams) Powder or 6 Capsules Amount Per Scoop Also Available From Klaire Labs ® Glutamine (as L-glutamine USP) PROBIOTICS An extensive selection of single and multispecies, dairy-free probiotic supplements are available in our Klaire Labs product line. PREBIOTICS Specific types of soluble dietary fiber called prebiotics nourish beneficial colonic flora and support immune function. BiotaGen® Combines inulin and other highly effective prebiotics with immunomodulating agents. Vegetarian capsules or pure powder. K-BTGC 120 vegetarian capsules K-BTG 5.3 oz (150 g) powder Galactomune® Combines galactooligosaccharides with betaglucan for Th1/Th2-immunomodulation actions. Vegetarian capsules or pure powder. K-GALC 60 vegetarian capsules K-GALC1 120 vegetarian capsules K-GAL 5.3 oz (150 g) powder To request a Klaire Labs® catalog call 888-488-2488. 3,750 mg* Gum arabic (Acacia senegal) 500 mg* 375 mg* Inulin 250 mg* 187 mg* N-Acetyl-D-Glucosamine 250 mg* (from crab and/or shrimp shells) 187 mg* *Daily Value not established. Other ingredients: Powder: None. Capsules: Vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, and silicon dioxide. Ther-Biotic® Complete Our most widely recommended probiotic formula providing 12 safe, well-documented species. Vegetarian capsules (25+ billion CFUs) and pure powder (100+ billion CFUs) options. V775-06 60 vegetarian capsules V775-12 120 vegetarian capsules K-TCP 2.1 oz (60 g) powder Amount 6 Capsules 5,000 mg* GSTP Powder Net Wt. 12.6 oz. (360 grams) 60 servings GSTC 180 vegetarian capsules SpectraFiber™ Supplement Facts Multi-source, bran-free. Serving Size 1 Capsule Combines purified and whole food concentrates containing a wide spectrum of natural soluble and insoluble fiber components including pectins, mucilages, algal polysaccharides, cellulose, hemicellulose, and lignan. Free of cereal grains and bran. Amount Per Capsule Plant Concentrate Blend 750 mg* Glucomannan (from Konjac root), Prune Fiber, Carrot root, Celery stalk and leaves, Apple Pectin, Citrus Pectin, Slippery Elm bark, Sodium Alginate, and Fennel seed SUGGESTED USE: 1 to 6 capsules daily with meals. *Daily Value not established. SPF 120 vegetarian capsules Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, and silicon dioxide. TheraDophilus™ A highly bioavailable and stable probiotic supplement. Dairy-free. Experts agree that to qualify as a high quality probiotic supplement, the beneficial bacteria must reach the site of action in the gut in quantities large enough to produce the desired effect. TheraDophilus™ contains three compatible microbial strains with clinically documented activity and implantation ability. Microencapsulation technology is used to coat the fragile bacteria with vegetable derived Supplement Facts fatty acids, thus helping to protect the Serving Size 1 Capsule microorganisms from destruction by Amount Per Capsule stomach acid and thereby enhance Probiotic Blend 80 mg* viability. This process also dramatically Supplying 3.0 billion viable increases shelf-life at room temperature microorganisms as Lactobacillus acidophilus, Lactobacillus rhamnosus, so that refrigeration is not required. and Bifidobacterium longum TheraDophilus™ is a good choice for *Daily Value not established. helping to reestablish a healthy balance ingredients: Cellulose, vegetarian capsule of lactic acid bacteria diminished by stress, Other (hydroxypropyl methylcellulose, water), vegetable infection, medication, or other factors. lipids, maltodextrin, L-leucine, and silicon dioxide. SUGGESTED USE: 1 to 3 capsules daily. CONTAINS SOY. TDO 90 vegetarian capsules 21 Enzymes Digestive Enzymes and Healthy GI Function Enzymes are specialized proteins that accelerate the speed of chemical reactions. Found in all living cells, enzymes are essential for digesting food, regulating biochemical reactions, generating energy, and repairing tissues, organs, and cells. Digestive enzymes break down food into simpler molecules that can be readily absorbed. They are secreted along the entire gastrointestinal tract. Some of the best known digestive enzymes include proteases and peptidases that break down proteins into amino acids, lipases that split fats into glycerol and free fatty acids, and amylases that break down starch into simple sugars. Enzymes are also present in raw foods. However, cooking destroys raw food enzymes, placing the full burden of digestion on the pancreas and other organs. Various health conditions can also affect the body’s production of certain enzymes. Inadequate amounts of digestive enzymes can result in nutrient malabsorption and be associated with gas, bloating, diarrhea, and abdominal discomfort. Supplementing with plant- or animal-derived enzymes can assist breakdown of food, enhance nutrient absorption, and support normal GI function. TheraGest™ Potent pancreatic enzymes. TheraGest™ contains USP porcine-derived pancreatin which provides reliable and consistent enzyme activity specific for fat, protein, and carbohydrate (starch). Pancreatin is a mixture of enzymes produced by the exocrine cells of the pancreas. Composed of amylase, lipase, and protease, pancreatin is traditionally used when pancreatic secretions are inadequate. Extra lipase, specific for dietary fat, is included in this preparation. TheraGest™ tablets are formulated to release the enzyme contents quickly upon reaching the small intestine to avoid destruction of enzymes by stomach acid. Supplement Facts SUGGESTED USE: Adults: 1 tablet daily with each meal. Do not exceed 7 tablets per day. Not intended for chewing. Do not take if allergic to pork. Children under 12 years of age should not use except on advice of physician. TGST 90 tablets Serving Size 1 Tablet Betaine HCl Support for low stomach acidity. Betaine hydrochloride promotes optimal gastric acidity to support protein digestion and absorption of minerals and other nutrients. This compound provides a supplemental source of hydrochloric acid, an acidifying compound normally produced by the stomach during digestion of foods. This product should only be taken by people who have reduced levels of stomach acid. Each 648 mg capsule is equivalent to a measurement of 10 grains. SUGGESTED USE: 1 to 2 capsules at the beginning of each meal. Do not chew or open capsules. Caution: Do not take if you have stomach or duodenal ulcers or are taking drugs that may cause ulcers. Do not take on an empty stomach. Supplement Facts Serving Size 1 Capsule Amount Per Capsule Betaine hydrochloride 648 mg* *Daily Value not established. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, silicon dioxide, and cellulose. BHC 100 vegetarian capsules Amount Per Tablet Pancreatin 8X USP 300 mg* Equivalent to 2,400 mg pancreatin USP with the following minimum enzyme activity: Lipase 9,000 USP Units* Protease 60,000 USP Units* Amylase 60,000 USP Units* Also Available From Klaire Labs® *Daily Value not established. Other ingredients: Cellulose, vegetable stearine, stearic acid, silicon dioxide, magnesium stearate, and cellulose coating. DIGESTIVE ENZYMES Vital-Zymes™ Complete V-Nzyme Blend™ Vegetarian enzyme blend especially formulated to aid digestion of legumes and other complex carbohydrate foods. V-Nzyme Blend™ utilizes natural microbial-based enzymes active over a wide pH range with enzyme activity specific for fat, protein, carbohydrate (starch), and cellulose. Extra amounts of cellulase to help break down dietary fiber and alpha-galactosidase to target complex carbohydrates found in common Supplement Facts gas-forming foods are Serving Size 1 Capsule included. Together, the Amount Per Capsule enzymes in this Enzyme Blend (derived from Aspergillus niger, 700 mg* combination help Aspergillus oryzae, and Rhizopus oryzae) with the following minimum enzyme activity: make legumes, Lipase 1,500 FIP** vegetables, and grains Protease 45,000 HUT** more digestible Acid Protease 150 SAP** Amylase 11,000 DU** therefore helping to Cellulase 18,000 CU** prevent uncomfortable Alpha-Galactosidase 300 GaIU** gas and bloating. *Daily Value not established. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), cellulose, slippery elm bark, marshmallow root, silicon dioxide, and magnesium stearate. **Units are those used in edition five (V) of the Food Chemicals Codex (FCC) VNZ 90 vegetarian capsules SUGGESTED USE: Adults: 1 capsule daily with each meal. This broad-spectrum digestive enzyme formula contains over 19 enzymes and is most often chosen for maximum support during dysbiosis, malabsorption, or intestinal inflammation. K-VZM 120 vegetarian capsules Vital-Zymes™ Chewable A chewable tablet option of Vital-Zymes™ Complete sweetened with xylitol and mannitol. K-VCH 180 tablets ANTIBIOFILM ENZYMES InterFase® This highly specialized, patent-pending enzyme formula supports normal gastrointestinal function and microflora by assisting degradation of biofilm communities of potentially pathogenic bacteria and yeast. K-INT 60 vegetarian capsules K-INT-12 120 vegetarian capsules InterFase Plus® Provides the same unique enzyme formulation as InterFase® with the addition of ethylenediaminetetraacetic acid (EDTA), which binds the metals needed for biofilm formation. K-INTP 120 vegetarian capsules To request a Klaire Labs® catalog call 888-488-2488. 22 Enzymes / Immune Function Quercetin-Bromelain Forté™ Systemic Enzymes and Inflammatory Responses Proteolytic enzymes (proteases), while essential for digestion of food protein, also serve a much larger metabolic role as modulators of inflammation throughout the body. Our inflammatory response mechanisms are a critical part of a healthy immune system. Inflammation is a normal response after injury, surgery, infection, or exposure to allergens, but prolonged inflammation may result in chronic pain, swelling, and even permanent tissue damage. By activating tissue repair and breaking down cellular debris generated during inflammation, proteolytic enzymes improve vascular permeability and modulate tissue restorative processes, helping to speed healing and return balance to tissues after injury, surgery, infection, or allergen exposure. Nattokinase NSK-SD® Supports fibrinolytic activity. Nattokinase is a proteolytic enzyme whose principle effect is fibrinolysis or degradation of fibrin, a fibrillar protein that when linked together forms the mesh essential for blood clot formation. Formation and breakdown of fibrin is delicately balanced. Too little fibrin can lead to bleeding while excessive fibrin is associated with abnormal blood clot formation and inflammation. Nattokinase also upregulates the body’s natural mechanism that guards against excess fibrin formation. Nattokinase may support healthy blood clotting, circulation, and platelet function by helping to maintain optimum function of the body’s normal fibrinolytic processes. Produced from fermentation of non-GMO soybean isolates by Bacillus subtilis natto. Standardized to fibrin activity units and free of vitamin K. SUGGESTED USE: 1 capsule twice daily, 12 hours apart, with or between meals. Use is contraindicated in persons with history of bleeding tendency. Supplement Facts Serving Size 1 Capsule Amount Per Capsule Nattokinase NSK-SD®** (2,000 FU) 100 mg* *Daily Value not established. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, cellulose, and silicon dioxide. **NSK-SD® is a registered trademark of Japan Bio Science Laboratory, Co., Ltd. Supports the body’s natural response to inflammation and allergens. Quercetin-Bromelain Forté™ provides a mixture of proteolytic enzymes and bioflavonoids that help regulate the immune response during inflammation as may occur during exposure to allergenic substances or irritants. Quercetin is a potent bioflavonoid that protects cells and tissues against free radical damage. Bromelain, papain, and pancreatin provide a mixture of protein-specific and other enzymes that help ensure proper breakdown of protein molecules that may otherwise cause Supplement Facts tissue irritation or allergic Serving Size 2 Tablets responses. Vitamin C, Amount Per 2 Tablets % Daily Value buffered with magnesium to Vitamin C (as magnesium ascorbate) 200 mg 333% eliminate acidity, supports Magnesium (as magnesium ascorbate) 25 mg 6% histamine metabolism, Quercetin 500 mg * detoxification processes, Rutin 50 mg * and collagen synthesis. Bromelain (600 GDU) 250 mg * 150 mg * Quercetin-Bromelain Forté™ Papain (300,000 PU) Pancreatin 8X USP 50 mg * is often useful for individuals Equivalent to 400 mg pancreatin USP with the following minimum enzyme activity: susceptible to allergens that Lipase 1,500 USP Units * affect the respiratory system. SUGGESTED USE: 2 tablets up to 4 times daily. Do not take if allergic to pork or sensitive to pineapple or papaya. QBF 100 tablets Protease Amylase *Daily Value not established. Other ingredients: Cellulose, stearic acid, carboxymethylcellulose sodium, vegetable gum, silicon dioxide, magnesium stearate, and cellulose coating. Serralase™ Proteolytic enzymes offer broad systemic support. Serralase™ provides potent, vegetarian proteases for use as a systemic enzyme formulation to support tissue repair and healing. Proteolytic enzymes activate cells mediating tissue repair and break down cellular debris associated with inflammation thereby improving vascular permeability, modulating tissue restorative processes, and speeding healing. Serratia peptidase, a highly active and specific endopeptidase, is widely used to assist recovery after surgery or trauma, support joint function, and assist the respiratory system in breaking down and clearing mucus. Highly purified, stable Serratia peptidase cultured from a bacterial source is used. Bromelain (from pineapple) and Papain (from papaya) broaden the proteolytic actions as each enzyme acts at different points on protein molecules. Catalase (bacterial source), a Supplement Facts ubiquitous body enzyme, renders hydrogen Serving Size 1 Tablet peroxide harmless. Enteric coating protects Amount Per Tablet (enteric-coated) enzyme activity against degradation by Proteolytic Enzyme Blend 390 mg* stomach acid. Serralase™ is more potent than Supplying the following vegetarian enzymes: many similar enzyme formulas, thus fewer Serratia peptidase** 15,000 SPU* Bromelain 360 GDU* tablets may be needed. SUGGESTED USE: General support: 1 to 3 tablets daily between meals. Aggressive Support: 3 to 6 tablets daily between meals. SRA 90 tablets SRA180 180 tablets NTK 60 vegetarian capsules ViraThera CF™ Echinacea herbal blend. Order ProThera and Klaire Labs products TOLL-FREE 7:30 AM • 5 PM Pacific time 888-488-2488 10,000 USP Units * 10,000 USP Units * Addition of olive leaf extract complements this formula’s benefits in assisting immune system responsiveness against bacterial and viral invasion by supporting T-cell activity, interferon production, macrophage function, natural killer cell activity, and regulation of mucous membrane inflammation. SUGGESTED USE: 1 to 4 capsules daily. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), cellulose, L-leucine, and silicon dioxide. VCF 60 vegetarian capsules Papain Catalase 450,000 PU* 75 IU* *Daily Value not established. Other ingredients: Cellulose, carboxymethylcellulose sodium, silicon dioxide, stearic acid, magnesium stearate, and enteric copolymer dispersion coating. **Peptizyme SP® is a registered trademark of Specialty Enzymes. Supplement Facts Serving Size 1 Capsule Amount Per Capsule Astragalus (Astragalus membranaceus) root, dried extract, min. 0.4% isoflavones Echinacea Blend Echinacea angustifolia root, dried extract, min. 4% total polyphenols and Echinacea purpurea aerial parts, dried extract, min. 4% total polyphenols European Elder (Sambucus nigra) flower Goldenseal (Hydrastis canadensis) root and rhizome, min. 5% total alkaloids as hydrastine Licorice (Glycyrrhiza glabra) root and rhizome, dried extract, min. 12% glycyrrhizin Olive (Olea europaea) leaf, dried extract, min. 6% oleuropein 125 mg* 125 mg* 50 mg* 75 mg* 100 mg* 125 mg* *Daily Value not established. 23 Immune Function Nutrient Influences on Liver Detoxification Pathways ™ NEW! Beta-Q Immune Beta-glucan plus quercetin offers synergistic immune support. Quercetin, a potent antioxidant bioflavonoid, and β-(1→3), β-(1→6) beta-glucan, a soluble dietary fiber, have complementary actions that favorably modulate the immune system. Their combined effects may be especially helpful in regulating the immune response during exposure to allergenic substances or irritants as they may assist in modulating inflammation, maintaining Supplement Facts serum IgE levels in the Serving Size 1 Capsule normal range, and Amount Per Capsule stabilizing mast cells Beta-Glucan (purified from 250 mg* and basophils. Can be Saccharomyces cerevisae) taken daily or as needed. Quercetin 250 mg* SUGGESTED USE: 1 capsule twice daily with food. BQI 60 capsules Detoxification The liver is equipped with a two-phase enzymatic, toxin neutralization process, known as Phase I and Phase II, that relies on numerous nutrients to support detoxification activities and protect against excessive free radical generation that might otherwise induce tissue damage. Endo- and Exotoxins PHASE I (Cytochrome P450 Enzyme Reactions) Required Nutrients and Cofactors Folate Riboflavin (B2) Vitamin B12 Niacin (B3) Vitamin B6 Glutathione Flavonoids *Daily Value not established. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, cellulose, and silicon dioxide. Intermediate Metabolites PHASE II Dual Detox ™ (Conjugation Pathways) Required Nutrients and Cofactors L-cysteine L-glycine L-methionine L-glutamine Taurine L-arginine D-glucarate L-ornithine N-acetyl-L-cysteine (NAC) S-adenosyl-L-methionine (SAMe) Methylsulfonylmethane (MSM) Trimethylglycine (Betaine) Binds intestinal toxins and supports liver detoxifying effects. This advanced blend of green plant concentrates and enzymes helps protect our bodies against chemicals we consume in our daily diets. Dual Detox™ is rich in chlorophylls from Chlorella and contains a unique concentrated broccoli extract high in glucosinolates and sulforaphane. The chlorophylls in Chlorella form tight molecular complexes with a wide variety of toxic chemical compounds preventing their absorption from the gastrointestinal tract. A special thin-cell wall type of Chlorella, not broken-cell, is used to protect the active compounds until ingested. A special blend of enzymes in Dual Detox™ then breaks down the Chlorella cell wall and releases the active components. This high-potency enzyme blend also breaks down dietary allergens and irritants and can help reduce Candida yeast activity in the intestinal tract by lysing Candida cell walls. Isothiocyanate compounds like sulforaphane in broccoli are potent inducers of phase 2 detoxification processes in the liver. Most substances detoxified by the liver are released into the bile for excretion through the intestinal tract. Chlorella helps trap these toxins to avoid reabsorption. Together, Chlorella and broccoli exert a dual detoxifying effect that reduces the overall Supplement Facts toxic burden on the body by Serving Size 1 Capsule enhancing liver processes and Amount Per Capsule interfering with absorption of Chlorella (Chlorella vulgaris) thin-cell wall 500 mg* toxins from the intestinal tract. Broccoli (Brassica oleracea italica) sprout, dried 60 mg* extract, min 6% glucosinolates and Dual Detox™ can be used as 0.3% sulforaphane an adjunct to short-term Enzyme Blend 155 mg* detoxification programs or for Supplying: Beta-Glucanase, Cellulase, Protease, Hemicellulase, Phytase, and Xylanase daily detoxification support. *Daily Value not established. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, cellulose, and silicon dioxide. SUGGESTED USE: 1 capsule twice daily with food. DTX 60 vegetarian capsules ImmunoThera™ Supports immunity, DNA repair. Contains AC-11®. AC-11® is a patented, water-soluble botanical extract of Uncaria tomentosa shown to uniquely support the body’s natural defenses at the molecular level against oxidative stress, inflammation, infection, and DNA damage. Combining AC-11® Supplement Facts and larch arabinogalactan not only enhances Serving Size 1 Tablet immune responsiveness but also promotes the Amount Per Tablet body’s natural DNA repair capacity. AC-11® helps AC-11®** patented water-soluble extract of 250 mg* counteract cell damage caused by oxidative stress. Uncaria tomentosa, min. 8% carboxy alkyl esters Larch Arabinogalactan (Larix occidentalis), 750 mg* Arabinogalactan is a natural polysaccharide dried water-soluble extract that stimulates beneficial immune cells resulting in a potent immunomodulating effect. Can be *Daily Value not established. Other ingredients: Cellulose, stearic acid, carboxymethylcellulose safely taken daily or as needed. sodium, silicon dioxide, magnesium stearate, and cellulose coating. SUGGESTED USE: 1 tablet twice daily with food. IMT 60 tablets 24 **AC-11® is a trademark of Optigenex Inc. AC-11® is protected by U.S. Patent Numbers 6,039,949, 6,238,675 B1, 6,361,805 B2, 6,964,784 B2, 7,579,023 B2, and 7,595,064 B2. Excretory Derivatives Reactive Oxygen Species Protective Antioxidant Nutrients Vitamin C Selenium Vitamin E Copper Carotenes Zinc Alpha-Lipoic Acid Manganese Flavonoids Coenzyme Q10 Thiols Silymarin (Milk thistle) Non-Reactive Derivatives Other Products that Support Liver Function and Detoxification Alpha-Lipoic Acid ........................ Glutathiol™ ................................ MSM® 750 .................................. MultiThera® .................................. N-Acetyl-L-Cysteine...................... SAMe 200 .................................... Taurine ........................................ TheraFlavone™ ............................ Page 15 Page 14 Page 30 Pages 5-6 Page 14 Page 32 Page 34 Page 13 Order ProThera and Klaire Labs products TOLL-FREE 7:30 AM • 5 PM Pacific time 888-488-2488 Liver Function and Detoxification Nourishing the Liver The liver is a remarkably resilient organ, but its ability to regenerate becomes vulnerable with increasing age and accumulated or excessive exposure to alcohol, aflatoxin, medication, infective agents, allergens, and other potentially harmful substances. Hepatic damage ranging from mild, asymptomatic inflammation to progressive fibrosis or cirrhosis can impair vital metabolic functions of protein synthesis, nutrient distribution, glucose storage, bile production, and clearance of metabolic waste products, hormones, drugs, and toxins. Nutrients that protect hepatocytes can be rapidly depleted when the liver is under stress, making it even more susceptible to damage. We provide several specific formula options to nutritionally support and protect hepatic function. Calcium D-Glucarate Enhances detoxification of hormones and toxins. D-glucarate supports Phase II glucuronidation, a primary detoxification pathway that deactivates toxins and promotes their elimination. D-glucarate plays a vital protective role for the immune system by inhibiting the beta-glucuronidase enzyme that can otherwise interfere with safe removal of carcinogens and steroid hormones such as estrogen. Beta-glucuronidase enzymes are active throughout the body, especially in the liver, colon, lungs, skin, bladder, breast, and prostate. SUGGESTED USE: 1 to 3 capsules daily with food. Supplement Facts Serving Size 1 Capsule Amount Per Capsule Calcium D-Glucarate** 500 mg* *Daily Value not established. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), cellulose, silicon dioxide, and magnesium stearate. **CDGlucarate™ brand. U.S. Patent Number 4,845,123 CDG 90 vegetarian capsules Dietary indole compounds as found in broccoli, cabbage, and other cruciferous vegetables exert a strong protective effect on tissues such as breast, cervix, and prostate that are most susceptible to the effects of undesirable estrogen metabolites, such as 16-alpha-hydroxyestrone. Indole compounds favorably influence steroid hormone metabolism and help rebalance estrogen in favor of 2-hydroxyestrone, a protective estrogen metabolite. Dietary indoles also stimulate liver detoxification enzymes, inhibit DNA damage, and regulate cell cycle progression. Indole-3-carbinol (I3C), the most prominent dietary indole, readily breaks down in the presence of stomach acid into diindolylmethane (DIM) and other associated indole compounds that are subsequently absorbed. Although diindolylmethane has been claimed to be the preferred form for dietary supplementation, published evidence does not adequately support this conclusion. The bulk of scientific data reports benefits from taking I3C. Data in direct support of taking DIM alone is suggestive but still inconclusive. Rather, it appears that the Supplement Facts total content of dietary indoles is most relevant. Indole Forté™ contains I3C, DIM, and other indoles Serving Size 1 Capsule Amount Per Capsule for more complete protection. Increased indole Total Dietary Indoles intake may be especially important for women or Proprietary blend containing indole-3-carbinol, diindolylmethane, men with estrogen-related health conditions. IND 60 vegetarian capsules This product contains L-methionine, an essential sulfur-containing amino acid that is used to form other amino acids such as cysteine and taurine as well as other important compounds such as S-adenosylmethionine, an important methyl donor. SUGGESTED USE: 1 capsule daily with food. Supplement Facts Serving Size 1 Capsule Amount Per Capsule 500 mg* *Daily Value not established. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, silicon dioxide, and cellulose. 400 mg* and related indole compounds SUGGESTED USE: 1 to 2 capsules daily with food. *Daily Value not established. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), silicon dioxide, cellulose, and L-leucine. HepatoThera™ General support for liver detoxification and protective enzyme pathways. This formula contains nutrients known to enhance intracellular levels of glutathione, glutathione peroxidase, and superoxide dismutase (SOD) — crucial antioxidants that protect hepatocytes and help detoxify foreign substances. The balance of supportive nutrients makes this product suitable to help strengthen the liver against everyday assaults on liver function. HEP 60 vegetarian capsules Essential sulfur amino acid. MET 100 vegetarian capsules Combines protective benefits of indole-3-carbinol, diindolylmethane, and other indoles. SUGGESTED USE: 1 capsule twice daily. L-Methionine L-Methionine Indole Forté™ Supplement Facts Serving Size 1 Capsule Amount Per Capsule Milk Thistle (Silybum marianum) fruit, dried extract, min. 80% silymarin N-Acetyl-L-Cysteine USP Alpha-Lipoic Acid L-Methionine L-Cysteine Taurine USP Trimethylglycine (betaine) 200 mg* 150 mg* 50 mg* 25 mg* 50 mg* 50 mg* 150 mg* *Daily Value not established. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), silicon dioxide, L-leucine, natural citrus flavor, and natural vanilla flavor. HepatoThera™ Forté Intensive support for viral and toxic challenges to liver function. Formulated to help meet the liver’s higher demand for nutrients that support antioxidant pathways, detoxification mechanisms, and enzyme regulation during Supplement Facts illness or significant Serving Size 1 Capsule exposure to chemical Amount Per Capsule % Daily Value toxins, heavy metals, Selenium (as L-selenomethionine) 135 mcg 193% drugs, hepatitis C and Milk Thistle (Silybum marianum) fruit, 200 mg * other viral burdens. dried extract, min. 80% silymarin SUGGESTED USE: 1 capsule three times daily. HEPF 90 vegetarian capsules N-Acetyl-L-Cysteine USP 200 mg * Alpha-Lipoic Acid 200 mg * *Daily Value not established. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, silicon dioxide, cellulose, natural citrus flavor, and natural vanilla flavor. 25 Fatty Acids Marine Fish Oil Premium Fish Oil Concentrates: High-potency EPA and DHA at an affordable price. Omega-3 EPA and DHA fatty acids found in cold water marine fish support many physiological processes related to immune function, regulation of inflammation, lipoprotein metabolism, brain function, and mood regulation. All ProThera fish oil supplements are molecularly distilled to ensure removal of heavy metals (mercury, lead, etc.), pesticides, and other contaminants. Marine Fish Oil is a concentrated product supplying 50% EPA/DHA content and is a very affordable option for daily omega-3 supplementation. Each 1,000 mg softgel supplies a guaranteed minimum amount of 300 mg EPA and 200 mg DHA (270 mg EPA/ 180 mg DHA when reported as free fatty acid equivalents). Marine Fish Oil is an unflavored product free of fishy smell or aftertaste. Mixed vitamin E tocopherols maintain freshness by retarding lipid peroxidation, preserving the light, clean taste. Each batch of softgels is analyzed by an independent testing laboratory to verify oil purity and omega-3 potency. Cholesterol-free. SUGGESTED USE: 1 to 6 softgels daily. Supplement Facts Serving Size 1 Softgel Amount Per Softgel % Daily Value Calories Calories from Fat Total Fat Saturated Fat 10 10 1g 0g Polyunsaturated Fat Vitamin E (as d-alpha tocopherol) from soy Marine Fish Oil Concentrate Supplying the following omega-3 fatty acids: Eicosapentaenoic Acid (EPA) 2%† 0%† 1g * 5 IU 17% 1,000 mg Compound FFA Weight** Weight*** 300 mg 270 mg Docosahexaenoic Acid (DHA) 200 mg * * †Percent Daily Values are based on a 2,000 calorie diet. *Daily Value not established. MAR 100 softgels Smaller size fish oil softgel, natural lemon flavor. Omega-3 Mini™ contains the same premium fish oil concentrate as our Marine Fish Oil softgels, but the capsules are half the size. This smaller softgel is often preferred by children and other individuals who have difficulty swallowing larger pills. Natural lemon flavor has been added to the oil, giving this product a light, citrus taste. Vitamin E tocopherols added to maintain freshness. Each batch is analyzed by an independent, third-party laboratory to verify oil purity and omega-3 potency. Cholesterol-free. Supplement Facts Serving Size 1 Softgel Amount Per Softgel % Daily Value Calories Calories from Fat Total Fat Saturated Fat Polyunsaturated Fat 5 5 0.5 g 0g 0.5 g Marine Fish Oil Concentrate Supplying the following Compound omega-3 fatty acids: Weight** Eicosapentaenoic Acid (EPA) 150 mg Docosahexaenoic Acid (DHA) 100 mg 500 mg FFA Weight*** 135 mg 90 mg < 1%† 0%† * * * * †Percent Daily Values are based on a 2,000 calorie diet. *Daily Value not established. SUGGESTED USE: 1 to 6 softgels daily. Other ingredients: Gelatin, glycerin, water, natural lemon oil, and natural mixed tocopherol vitamin E from soy. OM3 100 softgels EPA and DHA: Active Omega-3 Series Fatty Acids Strong scientific evidence supports the health benefits of omega-3 fatty acids, a specific class of polyunsaturated fats found primarily in fatty fish such as salmon, mackerel, sardines, and albacore tuna, but also found in flaxseeds, walnuts, and canola oil. In fish, omega-3 fats occur primarily as EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid). In plant foods, omega-3 occurs as alpha-linolenic acid, a precursor form that is slowly and often poorly converted to EPA and DHA in many individuals. By eating fish or taking fish oil supplements, omega-3 fats are ingested in their biologically active forms that can be directly used to help support cardiovascular, brain, nervous system, and immune functions. In general, 500 mg to 650 mg of omega-3 as EPA/DHA per day is recommended for good health. 26 Fresh, non-fishy taste: Many patients expect fish oil supplements to taste and smell fishy and are therefore reluctant to take them. The good news is that ProThera’s fish oil softgels – both flavored and unflavored – have no fishy smell or aftertaste. Extensive purification of the oil, careful handling to avoid oxidation, and addition of protective antioxidants retains the clean, pure taste. Finished product testing consistently shows very low peroxide and p-anisidine values, key indicators of a fresh, non-rancid product. Extra-strength: To help patients get the most out of taking fish oil supplements, each of our marine lipid concentrates delivers potent amounts of omega-3 fatty acids compared to standard fish oil supplements that supply about 30% EPA/DHA. In contrast, ProThera fish oils provide a minimum concentration of 50% and as much as 70% total EPA/DHA. Other ingredients: Gelatin, glycerin, and water. Omega-3 Mini™ Ensuring adequate omega-3 fatty acid intake by taking fish oil supplements has become a popular practice among both patients and physicians. However, wide differences in potency, purity, and cost complicate the selection of a quality product. To meet the need for consistently pure and cost-effective fish oils, ProThera employs stringent quality standards to ensure that all of our fish oil-containing supplements can be administered safely and reliably with maximum consumer acceptance. Exceptional purity: Starting with small species of wild fish harvested from cold, pristine, deep ocean waters, the oil used in ProThera products undergoes molecular distillation, ultra-filtration, and other purification processes to remove contaminants while maintaining nutritional integrity of the oil. This reduces mercury and other heavy metals, pesticides, PCBs, and dioxins to exceptionally low levels in strict adherence with international standards of purity. * 180 mg Pure. Potent. Affordable. Third-party tested: To verify purity and potency of our fish oil, each batch of finished, encapsulated product is submitted for independent laboratory testing. Extensive analyses using highly sensitive methodologies are employed to ensure that mercury, PCBs, dioxins, peroxides, and other markers of purity and freshness are in full compliance with international guidelines and the recommendations of the Council for Responsible Nutrition (CRN). Competitively-priced: Milligram-for-milligram of actual EPA/DHA provided per softgel, ProThera fish oil supplements are among the most costeffective choices when compared to other high-quality brands. Our reasonable prices and assurance of exceptional quality translate into improved patient compliance and reliable delivery of omega-3’s important benefits. **Amounts reported as weight of the fatty acid compound. ***Amounts reported as free fatty acid (FFA) equivalents by weight in accordance with voluntary CRN Monograph. Fatty Acids Understanding Omega-3 Content on Fish Oil Supplement Labels Comparing fish oil supplements from different manufacturers is often confusing and in some cases nearly impossible. Inconsistencies in labeling and analytical methodologies are partly responsible for the discrepancies in EPA/DHA potency represented on labels. Some products report omega-3 as a percentage of the oil, while others list the milligram weight of the fatty acid compound present. However, because different compounds have different EPA and DHA yields, the actual fatty acid content is overstated in both cases. In an effort to correct this problem, the Council for Responsible Nutrition (CRN), an industry trade organization, has recently proposed voluntary guidelines for labeling uniformity. In brief, CRN recommends that omega-3 fatty acid products report actual EPA and DHA content as free fatty acid equivalents. Similar to reporting “elemental” content of mineral compounds, expressing the actual weight of EPA and DHA in omega-3 compounds would allow for meaningful comparison by consumers regardless of the product form. All ProThera fish oil products are labeled according to CRN guidelines by reporting EPA/DHA as free fatty acid equivalents. Since most products on the market still report the higher compound weights, we have provided a comparison chart below to show how the different reporting methods apply to our products. Eicosamax® Our highest-potency ultra-pure fish oil containing 70% omega-3 fatty acid content. Eicosamax®, our highest-potency fish oil supplement, contains 70% highly purified omega-3 fatty acids, an amount well above the usual 18% EPA and 12% DHA concentrations found in many other brands. This exceptional fish oil is preferred by both physicians and patients due to its extra-strength formulation and fresh, non-fishy taste. Advanced molecular distillation processing superconcentrates the amount of EPA and DHA from fish oil for added convenience and enhanced benefit. The increased nutritional density of this oil makes it especially suitable when high amounts of omega-3 fatty acids are required to support cardiovascular, neurological, and immune functions. The potency, purity, and price of Eicosamax® compares favorably against other high-potency, highly refined fish oil products, making it a very cost-effective choice. Our proprietary formulation process ensures removal of residual fish proteins and other compounds that contribute to fishy smell and aftertaste. A natural vitamin E and rosemary oil antioxidant blend maintains stability by protecting against peroxide formation that can affect taste and reduce healthy benefits. Natural lemon flavor imparts a refreshing, hint-of-lemon taste that is enjoyed by patients and promotes compliance month after month. Each batch is analyzed by an independent, third-party laboratory to verify oil purity and omega-3 potency. Cholesterol-free. SUGGESTED USE: Eicosamax® Softgels: 1 to 6 softgels daily with food. SUGGESTED USE: Eicosamax® Liquid: 1 teaspoon daily with food. Packed under nitrogen. Refrigerate after opening. Eicosamax® Softgel Formula Eicosamax® Liquid Formula Supplement Facts Supplement Facts Serving Size 1 Teaspoon (Approx. 5 ml) • Servings Per Container 24 Serving Size 1 Softgel Amount Per Softgel % Daily Value Calories Calories from Fat Total Fat Saturated Fat Polyunsaturated Fat 10 10 1g 0g 1g 2%† 0%† * Marine Fish Oil Concentrate 1,000 mg Supplying the following Compound FFA omega-3 fatty acids: Weight** Weight*** Eicosapentaenoic Acid (EPA) 360 mg 330 mg Docosahexaenoic Acid (DHA) 270 mg For more information on Eicosamax® visit — eicosamax.com 250 mg Amount Per Teaspoon Calories Calories from Fat Total Fat Saturated Fat Polyunsaturated Fat % Daily Value 40 40 4g 0g 4g 6%† 0%† * * * Marine Fish Oil Concentrate 4,443 mg Supplying the following Compound FFA omega-3 fatty acids: Weight** Weight*** Eicosapentaenoic Acid (EPA) 1,600 mg 1,467 mg * Docosahexaenoic Acid (DHA) 1,200 mg 1,111 mg * * * †Percent Daily Values are based on a 2,000 calorie diet. *Daily Value not established. †Percent Daily Values are based on a 2,000 calorie diet. *Daily Value not established. Other ingredients: Gelatin, glycerin, natural mixed tocopherol vitamin E from soy, natural lemon oil, rosemary extract, and water. **Amounts reported as weight of the fatty acid compound. ***Amounts reported as free fatty acid (FFA) equivalents by weight in accordance with voluntary CRN Monograph. Other ingredients: Natural mixed tocopherol vitamin E from soy, natural lemon oil, and rosemary extract. **Amounts reported as weight of the fatty acid compound. ***Amounts reported as free fatty acid (FFA) equivalents by weight in accordance with voluntary CRN Monograph. EMX 60 softgels EMX120 120 softgels EML 4 fluid oz ProThera Fish Oil Supplement Comparison Product Order ProThera and Klaire Labs products TOLL-FREE 7:30 AM • 5 PM Pacific time 888-488-2488 Serving Size Total EPA/DHA (Area%)* Amount (weight) of Fatty Acid Compound** PER SERVING Actual “Elemental” Fatty Acid Content*** PER SERVING 270 mg EPA / 180 mg DHA Marine Fish Oil 1,000 mg softgel 50% 300 mg EPA / 200 mg DHA Omega-3 Mini 500 mg softgel 50% 150 mg EPA / 100 mg DHA 135 mg EPA / 90 mg DHA 1,000 mg softgel 70% 360 mg EPA / 270 mg DHA 330 mg EPA / 250 mg DHA 1 teaspoon 70% 1,600 mg EPA / 1,200 DHA 1,467 mg EPA / 1,111 DHA Eicosamax® Eicosamax® Liquid *Area % values compare content of EPA and DHA to other fatty acids that may be present in the fish oil. Amounts do not directly correlate with milligrams of EPA/DHA per gram of oil. **Weight of fatty acid compound includes weight of material bound to the fatty acid. ***Actual weight of EPA and DHA expressed as free fatty acid (FFA) equivalents. NOTE: When comparing potencies with other brands, it is important to note that some fish oil softgel products list the EPA and DHA content in TWO softgels. ProThera® labels show fatty acid amounts in ONE fish oil softgel. 27 Fatty Acids Omega-6 Series Fatty Acids Omega-6 fats found in many common vegetable oils (corn, safflower, sunflower) supply linoleic acid, one of two types of essential fatty acids necessary for good health. Omega-3 fats in salmon and other fatty fish, flax seeds, and walnuts, provide the other type of essential fats. When omega-6 fats predominate over omega-3, inflammation-promoting substances are produced. Although most Western diets contain too much omega-6 and not enough omega-3, specific forms of omega-6 fats are sometimes needed to compensate for the body’s reduced ability to convert linoleic acid to its active form, gamma linolenic acid (GLA). Consumption of trans fats, viral exposures, and the aging process are some of the factors that can interfere with formation of GLA. GLA-rich borage oil and evening primrose oil can be helpful in creating "good" prostaglandins, hormonelike molecules that help regulate inflammation and blood pressure and nourish skin cells. NOW ORGANIC! Flax Seed Oil Organic source of essential fatty acids plus lignans. Evening Primrose Oil Bioactive GLA, organic source. Supplement Facts Serving Size 1 Softgel Amount Per Softgel % Daily Value Flax seed oil supplies a naturally-occurring balance of alpha-linolenic acid (omega-3) and linoleic acid (omega-6), essential polyunsaturated fatty acids important for healthy hair, skin, and nails, and as precursors for anti-inflammatory prostaglandins. Flax seed particulate containing protective lignan components is retained in the oil. Cold-pressing of flax seeds and natural caramel color in the softgel protects against heat and light-induced oxidation of fatty acids. Calories Calories from Fat Total Fat Saturated Fat Polyunsaturated Fat SUGGESTED USE: 1 to 9 softgels daily. †Percent Daily Values are based on a 2,000 calorie diet. *Daily Value not established. FLX 100 softgels 10 10 1g 0g 1g Organic Flax Seed Oil (cold-pressed) 1,000 mg Supplying approximately: Omega-3 fatty acids (as alpha-linolenic acid) 445 mg Omega-6 fatty acids (as linoleic acid) 130 mg Omega-9 fatty acids (as oleic acid) 145 mg Flax seed particulate (lignan-rich) 190 mg 2%† 0%† Serving Size 1 Softgel Amount Per Softgel * * * * Other ingredients: Gelatin, glycerin, natural caramel color, and water. Certified Organic by QAI. % Daily Value Calories Calories from Fat Total Fat Saturated Fat 10 10 1g 0g Polyunsaturated Fat Evening Primrose Oil Supplying a minimum of: Gamma-Linolenic Acid (GLA) Linoleic Acid Oleic Acid 1g 1,300 mg 130 mg 955 mg 80 mg 2%† 0%† * * * * * †Percent Daily Values are based on a 2,000 calorie diet. *Daily Value not established. Although Western diets typically contain large amounts of omega-6 essential fatty acids from Supplement Facts corn and safflower oils, the body’s conversion to Serving Size 1 Softgel %Daily Value the active GLA form can be impeded by various Amount Per Softgel 10 factors, thus disturbing fatty acid balance in favor Calories Calories from Fat 10 of synthesis of proinflammatory compounds. Total Fat 1g 2%† Borage oil provides a higher ratio of GLA to Saturated Fat 0g 0%† linoleic acid than evening primrose oil and similar Polyunsaturated Fat 1g * plant oils and can be used to help reestablish a Borage Oil (cold-pressed) 1,000 mg * healthier omega-6 fatty acid balance. Cold pressed Supplying approximately: and free of hexane or other solvents. Natural Gamma-Linolenic Acid (GLA) 220 mg * caramel color in the softgel protects against †Percent Daily Values are based on a 2,000 calorie diet. *Daily Value not established. light-induced oxidation of fatty acids. 28 Supplement Facts * Concentrated source of omega-6 GLA. BRG 100 softgels SUGGESTED USE: 1 to 3 softgels daily with food. * Borage Oil SUGGESTED USE: 1 softgel daily with food. Evening primrose is valued as a premium source of gamma-linolenic acid (GLA). These 1,300 mg softgels contain 130 mg biologically active GLA. Cold-pressed without hexane or other solvents. Other ingredients: Gelatin, glycerin, water, and natural caramel color. Other ingredients: Gelatin, glycerin, water, and natural caramel color. Certified Organic by QAI. EPO 100 softgels Fatty Acids Conjugated Linoleic Acid (CLA) OmegaThera™ A unique mix of omega-3, 6, and 9 fatty acids plus conjugated linoleic acid to help rebalance A potent cell protectant and regulator of body fat composition. fatty acid intake. This naturally-occurring derivative of linoleic acid is an omega-6 fatty acid with unique physiological effects on fat metabolism and the immune system. These effects are quite different from those of linoleic acid and in fact may provide a natural counterbalance to the potentially harmful actions of too much linoleic acid. CLA exerts antioxidant-like activity that helps keep excessive cell proliferation in check. It also exerts a favorable effect on the way the body burns and stores fat. Contains 78% total CLA with a minimum concentration of 74% biologically active isomers most commonly associated with physiological effect. Vitamin E and natural caramel coloring help maintain freshness by protecting against lipid oxidation. SUGGESTED USE: 1 to 3 softgels daily with food. Supplement Facts Serving Size 1 Softgel Amount Per Softgel Calories Calories from Fat Total Fat Saturated Fat Polyunsaturated Fat % Daily Value 10 10 1g 0g 1g Conjugated Linoleic Acid (CLA) Oil 1,000 mg from safflower Supplying a minimum of: Conjugated Linoleic Acid 780 mg 2%† 0%† * * * †Percent Daily Values are based on a 2,000 calorie diet. *Daily Value not established. Other ingredients: Gelatin, glycerin, natural caramel color, water, and natural mixed vitamin E tocopherols. CLA9 90 softgels This mixed fatty acid supplement supplies important fatty acids that are often difficult to obtain from the diet. OmegaThera™ was formulated to favor omega-3 fatty acids over omega-6 fatty acids to help maintain a healthy fatty acid ratio when added to typical diets that tend to be too low in omega-3. Omega-3 fatty acids are present as alpha-linolenic acid, an essential dietary fatty acid, as well as EPA and DHA, activated forms of omega-3 known for their ability to support a variety of physiological processes, including regulation of inflammation, immune function, lipoprotein metabolism, and brain function. Omega-6 fatty acids are also supplied in several important forms, including linoleic acid (LA), an essential dietary fatty acid, and gamma-linolenic acid (GLA), the activated form of omega-6 whose conversion from LA may be compromised by poor diet and other factors. Supplement Facts Conjugated linoleic acid Serving Size 1 Softgel (CLA), a variant of linoleic Amount Per Softgel % Daily Value acid, favorably influences Calories 10 fat metabolism and offers Calories from Fat 10 unique cell protective Total Fat 1g 2%† Saturated Fat 0g 0%† benefits. Oleic acid, an Polyunsaturated Fat 1g * omega-9 fatty acid, is Vitamin E (as natural mixed tocopherols) from soy 1 IU 3% also present as a natural Marine Fish Oil Concentrate 550 mg * constituent of flax seed Supplying the following Compound FFA oil. OmegaThera™ omega-3 fatty acids: Weight** Weight*** Eicosapentaenoic Acid (EPA) 165 mg 149 mg * combines concentrated Docosahexaenoic Acid (DHA) 110 mg 99 mg * amounts of key nutritional Organic Flax Seed Oil (cold-pressed) 150 mg * fatty acids derived from Supplying approximately: premium plant Alpha-Linolenic Acid (ALA) 67 mg * seeds and fish oils Linoleic Acid (LA) 22 mg * in one convenient Oleic Acid 22 mg * Borage Seed Oil (Cold-Pressed) 50 mg * product. Natural Supplying approximately: carob coloring and vitamin E added to the softgel Gamma-Linolenic Acid (GLA) 10 mg * maintain freshness by protecting against fatty Linoleic Acid (LA) 22 mg * acid oxidation. Conjugated Linoleic Acid (CLA) Oil 250 mg * from safflower Supplying approximately: Conjugated Linoleic Acid SUGGESTED USE: 1 to 4 softgels daily with food. 175 mg * †Percent Daily Values are based on a 2,000 calorie diet. *Daily Value not established. **Amounts reported as weight of the fatty acid compound. ***Amounts reported as free fatty acid (FFA) equivalents by weight in accordance with voluntary CRN Monograph. OMG 100 softgels Other ingredients: Gelatin, glycerin, water, and natural carob coloring. OMEGATHERA™ FATTY ACID ACTIONS Eicosapentaenoic Acid (EPA) TOLL-FREE 7:30 AM • 5 PM Pacific time 888-488-2488 Direct precursor of anti-inflammatory eicosanoids (prostaglandins, leukotrienes, thromboxanes); supports integrity of epithelial tissues of vascular system, lungs and intestinal tract; regulates serum triglycerides; supports platelet function. Docosahexaenoic Acid (DHA) Supports brain function as major fatty acid in neuronal cell membranes; supports visual function as structural component of retina; regulates serum triglycerides and lipids, especially HDL-cholesterol. Alpha-Linolenic Acid (ALA) Essential omega-3 fatty acid supports skin and epithelial cell membrane integrity; component of myelin sheath insulating nerve fibers; supports prostaglandin balance and insulin metabolism. Linoleic Acid (LA) Essential omega-6 fatty acid; precursor to GLA. Oleic Acid Decreases LDL susceptibility to oxidation; protects endothelial cells. Gamma-Linolenic Acid (GLA) Supports cell membrane flexibility; precursor of 1-series prostaglandins that modulate inflammatory reactions in skin, joints, and connective tissues; supports peripheral nerve function. Conjugated Linoleic Acid (CLA) Supports cholesterol and triglyceride metabolism; scavenges free radicals; modifies eicosanoid formation; regulates body fat composition; modulates immune response to inflammation. 29 Joint/Connective Tissue Function Myalgesin® Glucosamine Sulfate Supportive actions for joint function. Vegetarian formula supports muscle comfort and mobility. Research continues to confirm glucosamine as a beneficial nutritional precursor that supports synthesis of joint and connective tissues. Sodium-free, potassium-stabilized form. Research demonstrates celery seed extract helps regulate inflammatory processes involved in minor pain affecting muscle and joint tissue. A compound unique to celery, 3-n-butylphthalide (3nB), appears to be responsible for its healing actions. By helping restore prostaglandin balance and enhance blood flow, celery seed extract had noticeable positive benefit on muscle and joint function in individuals studied over a 3 to 6 week period. Myalgesin® also contains a concentrated boswellia extract supplying Supplement Facts AKBA, a 5-lipoxygenase Serving Size 1 Capsule inhibitor, and a unique phellodendron extract with Amount Per Capsule (Apium graveolens) seed, dried extract, min. 85% 75 mg* natural COX-2 regulatory Celery total phthalides (3-n-butylphthalide and sedanenolide) action. Suitable for 5-LOXIN ** Indian Frankincense (Boswellia serratta) extract, 25 mg* min. 30% AKBA (3-O-acetyl-11-keto-beta-boswellic acid) patients with osteoarthritis, *** Phellodendron (Phellodendron 250 mg* rheumatoid arthritis, gout, Nexrutine amurense) bark, dried extract and fibromyalgia. SUGGESTED USE: 1 capsule twice daily with food. Supplement Facts Serving Size 1 Capsule Amount Per Capsule Glucosamine Sulfate.2KCl (from crab and/or shrimp shells) 750 mg* *Daily Value not established. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), cellulose, L-leucine, and silicon dioxide. ® GLS 120 vegetarian capsules ® Glucosamine/ Chondroitin *Daily Value not established. SUGGESTED USE: 1 capsule twice daily with food or more Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, L-leucine, and silicon dioxide. as directed by practitioner. water), **5-LOXIN® is a registered trademark of PL Thomas-Laila Nutra, LLC and MYG 60 vegetarian capsules is under license. International patents pending. ***Nexrutine® is a registered trademark of Next Pharmaceuticals, Inc. A popular combination for the joints. ArthroThera ™ A two-phase approach for support of connective tissue and joint function. ArthroThera™ addresses two nutritional problems commonly observed in patients with compromised joint function: inadequate formation of structurally sound joint and cartilage tissue, and poor regulation of the body’s natural inflammatory response. Glucosamine and chondroitin supply dietary precursor compounds for the synthesis of joint cartilage and connective tissues. Bromelain, a proteolytic enzyme, and devil’s claw extract support Supplement Facts the body’s natural response to inflammation. Serving Size 2 Tablets Together, these substances help the body cope with Amount Per 2 Tablets (enteric-coated) the consequences of chronic stress and aging of Glucosamine Sulfate.2KCl (from crab and/or shrimp shells) 750 mg* connective tissues. The potency and activity of Chondroitin Sulfate 600 mg* Devil’s Claw (Harpagophytum procumbens) 375 mg* bromelain and devil’s claw are protected against root, dried extract, min. 2.5% harpagosides degradation by stomach acid by an acid-resistant Bromelain (2,000 GDU/gram) 375 mg* tablet coating. Daily use for a minimum of four *Daily Value not established. weeks is recommended to obtain maximum benefit. Other ingredients: Cellulose, stearic acid, carboxymethylcellulose sodium, silicon dioxide, magnesium stearate, and enteric copolymer dispersion coating. SUGGESTED USE: 2 tablets twice daily with meals. ArthroTheraPack™ MSM 750 Broad support for joint tissues. Bioavailable sulfur. Connective tissue structure and function and regulation of inflammatory processes are influenced by many nutritional factors. ArthroTheraPack™ contains a broad array of nutrients to support a healthy fatty acid balance, a plentiful supply of cartilage precursors, antioxidant levels, and mineral nutrition. Even though little research exists to support the health claims made for MSM®, it has a demonstrated high level of safety and usefulness as a ready source of sulfur — an important mineral for detoxification pathways, connective tissue metabolism, antibody formation, and synthesis of other organosulfur compounds. Added molybdenum aids sulfur metabolism. ARTP 30 packets Each packet contains: 3 MultiThera® 1 tablets • 2 ArthroThera™ tablets • 2 OsteoThera™ tablets • 1 Marine Fish Oil softgel. See pages 5, 26, 30, and 38 for full ingredient information. ® SUGGESTED USE: 1 capsule twice daily with food. Supplement Facts Serving Size 1 Capsule Amount Per Capsule Glucosamine Sulfate.2KCl (from crab and/or shrimp shells) 500 mg* Chondroitin Sulfate 400 mg* *Daily Value not established. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, cellulose, and silicon dioxide. GCH 90 vegetarian capsules Turmeric 250 Oral absorption of curcumin, the active component in turmeric, is generally poor due to its low solubility and instability in the intestinal environment. Meriva® combines turmeric extract with phosphatidylcholine from soy lecithin forming a bioavailable turmeric phytosome complex that is significantly better absorbed than regular turmeric extracts. Meriva® phytosome complex greatly increases curcumin stability and enhances oral absorption by over 20-fold. SUGGESTED USE: 1 capsule twice daily with food. Supplement Facts Amount Per Capsule Amount Per Capsule % Daily Value Molybdenum (as molybdenum glycinate chelate**) 25 mcg 33% 750 mg * *Daily Value not established. 30 Supplement Facts Serving Size 1 Capsule Serving Size 1 Capsule Methylsulfonylmethane (MSM®***) SUGGESTED USE: 1 capsule three times daily with food. Meriva® turmeric phytosome enhances curcumin bioavailability. ART 120 tablets SUGGESTED USE: 1 packet twice daily with food. Chondroitin sulfate supports synthesis of cartilage tissue and inhibits cartilage-degrading enzymes. Using both chondroitin and glucosamine offers related but distinctive benefits. Turmeric Phytosome** (Curcuma longa) root, dried extract, min. 18% curcuminoids, phosphatidylcholine complex 250 mg* *Daily Value not established. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), cellulose, L-leucine, and silicon dioxide. **Albion® Laboratories. ***MSM® is the registered trademark for licensed methylsulfonylmethane, a naturally-occurring source of sulfur, an essential mineral. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, cellulose, and silicon dioxide. **Meriva® brand bioavailable curcumin. Meriva® is a registered trademark of Indena S.p.A., Milan. MSM 100 vegetarian capsules TRM 100 vegetarian capsules CONTAINS SOY. Inflammation Support Turmeric 500 NEW! High-potency Meriva® turmeric phytosome complex. This potent turmeric supplement delivers 500 mg of Meriva® phytosome complex per capsule for situations where extra amounts of highly bioavailable curcumin may be useful. Meriva® is a unique turmeric phosphatidylcholine complex that is significantly better absorbed than regular turmeric extracts. By greatly increasing curcumin stability, Meriva® enhances oral absorption by over 20-fold, thus helping to maximize turmeric’s powerful, protective benefits on tissues throughout the body. SUGGESTED USE: 1 capsule twice daily with food. Supplement Facts Contains Meriva ® Turmeric Phytosome A unique phytonutrient mixture to help regulate inflammatory response. The body’s ability to maintain a natural balance of enzymes such as cyclooxygenase-1 and 2 (COX-1 and COX-2) that help regulate inflammatory physiological response mechanisms and detoxification enzymes is critical to the health of the entire body. In fact, these metabolic processes play a crucial role in supporting cardiovascular, immune, neurological, joint, and connective tissue functions. Each of the herbal extracts in InflaThera™ contains multiple, beneficial compounds and has documented ability to help modulate COX enzymes, scavenge free radicals, and promote physiological balance in susceptible tissues in a safe and harmonious fashion. Meriva® brand turmeric, a key ingredient in InflaThera™, combines turmeric extract with phosphatidylcholine forming a bioavailable turmeric phytosome complex that is significantly better absorbed than regular turmeric extracts. InflaThera™ is a powerful, synergistic combination that can be useful for almost all types of patients. SUGGESTED USE: 1 capsule twice daily with food. Supplement Facts Serving Size 1 Capsule Amount Per Capsule Serving Size 1 Capsule Amount Per Capsule Turmeric Phytosome** (Curcuma longa) root, dried extract, min. 18% curcuminoids, phosphatidylcholine complex InflaThera™ 500 mg* *Daily Value not established. Turmeric Phytosome** (Curcuma longa) root, dried extract, min. 18% curcuminoids, phosphatidylcholine complex 250 mg* Rosemary (Rosmarinus officinalis) leaf, dried extract, min. 6% carnosic acid, and min. 1% ursolic acid 100 mg* Holy Basil (Ocimum tenuiflorum) leaf, dried extract, min. 2% ursolic acid 100 mg* Green Tea (Camellia sinensis) leaf, dried extract, min. 50% catechins (polyphenols) 100 mg* Ginger (Zingiber officinalis) root, dried extract, min. 5% gingerols 50 mg* Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, cellulose, and silicon dioxide. **Meriva® brand bioavailable curcumin. Meriva® is a registered trademark of Indena S.p.A., Milan. Coptis (Coptis chinensis) root, dried extract, min. 10% berberine 25 mg* Barberry (Berberis vulgaris) root, dried extract, min. 6% berberine 25 mg* Chinese Skullcap (Scutellaria baicalensis) root, dried 5:1 extract 13 mg* CONTAINS SOY. Japanese Knotweed (Polygonum cuspidatum) root, dried extract, min. 50% resveratrol 2 mg* TRM5 100 vegetarian capsules *Daily Value not established. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, cellulose, and silicon dioxide. Gliatrol™ Neuroprotective actions modulate microglial cell inflammation. Immune cells called microglia can trigger inflammation in the central nervous system. When normal CNS inflammatory balance is disrupted, potentially harmful brain inflammation can occur. Gliatrol™ combines specific botanicals that modulate microglial activation and provide potent antioxidant actions that protect hippocampal neurons needed for maintaining cognitive function during aging. SUGGESTED USE: 1 capsule daily with food. Supplement Facts Serving Size 1 Capsule Amount Per Capsule Blueberry (Vaccinium corymbosum) fruit, dried extract, min. 15% anthocyanins 100 mg* Green Tea (Camellia sinensis) leaf, dried extract, min. 50% 100 mg* epigallocatechin gallate, min. 95% polyphenols Turmeric Phytosome** (Curcuma longa) root, dried extract, 100 mg* min. 18% curcuminoids, phosphatidylcholine complex LutiMax®*** Luteolin/Rutin complex 75 mg* trans-Pterostilbene**** (methylated resveratrol) 25 mg* Lecithin (from soy) 75 mg* *Daily Value not established. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), cellulose, L-leucine, and silicon dioxide. **Meriva® brand bioavailable curcumin. Meriva® is a registered trademark of Indena S.p.A., Milan. ***Manufactured under license of US Patent No. 6,774,142 from LutiMax Nutraceuticals, LLC. ****pTeroPure™ brand, a trademark of ChromaDex, Inc. CONTAINS SOY. GLT 30 vegetarian capsules **Meriva® brand bioavailable curcumin. Meriva® is a registered trademark of Indena S.p.A., Milan. CONTAINS SOY. INF 60 vegetarian capsules INGREDIENT ACTIONS Turmeric Phytosome Complex min. 18% curcuminoids Rosemary Leaf Extract min. 6% carnosic acid, min. 1% ursolic acid Holy Basil Leaf Extract min. 2% ursolic acid Inhibits proinflammatory enzymes in arachidonic acid cascade; general antioxidant and nitric oxide scavenger; supports platelet function. Inhibits synthesis of leukotrienes and prostaglandins; neutralizes free radicals; stimulates Phase II liver detoxification. Helps modulate activity of proinflammatory enzymes and eicosanoids; protects gastric tissues; supports capillary integrity following inflammatory stimuli; protects against radiation-induced damage. Green Tea Leaf Extract Helps regulate proinflammatory enzymes and arachidonic acid min. 50% catechins metabolites; slows leukocyte migration into tissues; potent antioxidant. Ginger Root Extract Modulates inflammatory cascade reactions; supports platelet function; min. 5% gingerols protects gastric lining. Coptis Root Extract Supports rebalancing of COX enzymes; inhibits lipid peroxidation; min. 10% berberine supports platelet function. Barberry Root Extract Supports rebalancing of COX enzymes; inhibits lipid peroxidation; 6% berberine supports platelet function. Chinese Skullcap Root Extract Inhibits both COX-2 and 5-lipoxygenase pathways; potent flavonoid 5:1 extract antioxidant protection. Japanese Knotweed Extract Reduces prostaglandin synthesis; strong antioxidant protection against min. 50% resveratrol reactive oxygen molecules. InflaTheraPack™ Multinutrient support for regulating inflammation. Combines omega-3 fatty acids, quercetin, and various botanicals that inhibit enzymes of the arachidonic cascade. Proteolytic enzymes help ensure proper breakdown of proteins that may otherwise become tissue irritants. Each packet contains: 3 MultiThera® 1 tablets SUGGESTED USE: 1 packet twice daily with food. • 2 OmegaThera™ softgels • 1 InflaThera™ capsule INFP 30 packets • 2 Quercetin-Bromelain Forté™ tablets. See pages 5, 23, 29, and 31 for full ingredient information. 31 NeuroNutrients 5-HTP SAMe 200 Versatile nutrient supports mood regulation, joints, and liver function. An impressive amount of research and long history of clinical use documents the benefits of SAMe. As a modulator of cell membrane fluidity and neurochemical activity in the central nervous system, it helps support mood and optimal brain function. The sulfur in SAMe is used to help build cartilage and strong joints and for synthesis of taurine and glutathione, used in liver detoxification processes. SAMe also helps synthesize polyamines required for normal cell growth. The reactive nature of SAMe prevents it from being used in combination nutrient products, but it can be stabilized as a single ingredient with careful manufacturing and an enteric tablet coating. ProThera provides pharmaceutical grade, stabilized SAMe manufactured under low temperature and low humidity conditions. An enteric tablet coating is applied to further ensure a biologically active product. Each tablet Supplement Facts contains a full 200 mg Serving Size 1 Tablet of elemental SAMe Amount Per Tablet (enteric-coated) from 400 mg SAMe S-Adenosyl L-Methionine (from 400 mg of 200 mg* tosylate disulfate. S-Adenosyl L-Methionine tosylate disulfate) SUGGESTED USE: 1 to 6 tablets daily between meals. SAM 30 tablets SAM60 60 tablets *Daily Value not established. Other ingredients: Cellulose, mannitol, sodium starch glycolate, silicon dioxide, glyceryl behenate, magnesium stearate, enteric coating (methacrylate copolymers), titanium dioxide, magnesium silicate, triethylcitrate, riboflavin, glycerol palmitostearate, and medium chain triglycerides. MigraThera™ Influences serotonin and melatonin levels. L-5-hydroxytryptophan is a safe, natural alternative to tryptophan which is used to form serotonin, a brain neurohormone essential for melatonin production, appetite control, and mood regulation. Our 5-HTP is a natural extract of griffonia seeds and certified free of Peak X. Available in 50 mg or 100 mg. SUGGESTED USE: 1 to 2 capsules daily. Supplement Facts Serving Size 1 Capsule Amount Per Capsule 50 mg 100 mg L-5-Hydroxytryptophan (5-HTP) 50 mg* 100 mg* *Daily Value not established. Other ingredients: Cellulose, vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, and silicon dioxide. 5HTP (50 mg) 100 vegetarian capsules 5HTP1 (100 mg) 100 vegetarian capsules GABA Riboflavin plus feverfew. Calming neurotransmitter. Clinical studies have shown similar benefits through different mechanisms for feverfew herb and high amounts of riboflavin (vitamin B2) on processes affecting inflammatory responses, particularly in the brain. The complex mixture of sesquiterpene Supplement Facts lactones and other compounds in feverfew Serving Size 1 Capsule favorably influence eicosanoid metabolism, % Daily Value while riboflavin increases mitochondrial energy Amount Per Capsule Riboflavin USP 400 mg 23529% efficiency. We include feverfew in both its Feverfew (Tanacetum parthenium) leaf 100 mg * whole herb and standardized extract forms to Feverfew (Tanacetum parthenium) leaf, 50 mg * retain the full spectrum of activity. Regular use dried extract, min. 0.2% parthenolide confers maximum benefit. Gamma-Aminobutyric acid (GABA), as the major inhibitory neurotransmitter in the central nervous system, helps maintain normal brain function. SUGGESTED USE: 1 to 2 capsules daily with food. *Daily Value not established. MGR 60 vegetarian capsules Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), silicon dioxide, and magnesium stearate. Inositone™ L-Theanine Powdered inositol supports mood regulation and brain function. Myo-inositol is a key cell membrane component and messenger in our neuro-communication system that signals release of serotonin and norepinephrine. It also triggers other cell functions related to glucose and fat metabolism. Controlled studies using several grams of inositol daily have shown a positive benefit on mood and emotional stability in specific clinical applications. Each 1/4 teaspoon contains 700 mg of pure myo-inositol with no added ingredients. SUGGESTED USE: 1/4 to 1 teaspoon daily. Mix with water or other liquid. Supplement Facts Promotes relaxation. L-theanine, a unique amino acid compound found in green tea, is noted for its calming benefits. Suntheanine® brand pure L-theanine is produced through a patented manufacturing process. Studies with Suntheanine® show it can stimulate alpha brain wave activity and promote relaxation without drowsiness. SUGGESTED USE: 1 to 2 capsules daily between meals. Supplement Facts Serving Size 1 Capsule 100 mg* *Daily Value not established. Serving Size 1/4 Teaspoon *Daily Value not established. Other ingredients: None. IPD Powder Net Wt. 10 oz. 284 grams 32 Serving Size 1 Capsule Amount Per Capsule GABA (gamma-aminobutyric acid) 500 mg* *Daily Value not established. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, and silicon dioxide. GABA 60 vegetarian capsules GABA Plus For a relaxed, balanced mood. Provides complementary nutrients to support normal mood function. GABA, the major inhibitory neurotransmitter in the central nervous system, helps maintain normal brain function and exerts a calming influence. The amino acids taurine and glycine support activity of calming neurotransmitters. Inositol, a key membrane component, signals release of serotonin and norepinephrine, thus helping to balance mood and emotional stability. Supplement Facts Serving Size 1 Capsule Amount Per Capsule Amount Per Serving Inositol Supplement Facts SUGGESTED USE: 1 to 2 capsules daily between meals. Amount Per Capsule L-Theanine** SUGGESTED USE: 1 capsule, 1 to 2 times daily between meals or as directed by physician. 700 mg* Other ingredients: Cellulose, vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, and silicon dioxide. **Suntheanine® brand. Suntheanine is a registered trademark of Taiyo International, Inc. GABA (gamma-aminobutyric acid) LTH 60 vegetarian capsules *Daily Value not established. 100 mg* Glycine 50 mg* Inositol 650 mg* Taurine USP 50 mg* Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), silicon dioxide, magnesium stearate, and cellulose. GBP 60 vegetarian capsules NeuroNutrients NeuroThera™ Ginkgo Biloba Improves absentmindedness. Ginkgo extracts are used to enhance mental function by increasing blood supply to the brain. Antioxidant flavonoids and terpene lactones in ginkgo support tone and elasticity of arteries and capillaries and help maintain "non-sticky" blood platelets. Our 24% extract is standardized to contain the amounts of active compounds used in the majority of research studies. Certified to contain less than 1% ginkgolic acid, an undesirable component, thus exceeds specifications of the German Commission E. Offers combined cognitive function benefits of 12 key neuronutrients. This formulation is a prime example of why we emphasize a coordinated, multinutrient approach whenever possible to promote maximum benefit and safety. The brain’s complex metabolism requires many different nutrients for optimum cellular communication and a balanced response to stress. Excessive or chronic release of adrenaline and cortisol, accumulated effects of toxins, and impeded flow of oxygen and nutrients can damage the brain and disrupt mental alertness, memory, and other functions. While using one or two neurosupportive nutrients can help target specific areas of function, care is needed to avoid potentially harmful effects of overstimulating only one neurotransmitter pathway. The ingredients in NeuroThera™ were chosen for their complementary and documented roles in neuronutrition and are supported by other key neuronutrients in MultiThera® multiple vitamin/mineral formulas. Used daily, this combined spectrum of nutrients may improve absentmindedness and other mild memory SUGGESTED USE: 1 to 3 capsules daily. For maximum problems associated with aging. benefit, use for a minimum of two months and SUGGESTED USE: 2 tablets daily with food. continue as long as needed. Supplement Facts Supplement Facts Serving Size 2 Tablets Serving Size 1 Capsule Amount Per 2 Tablets Amount Per Capsule Ginkgo (Ginkgo biloba) leaf, dried extract, min. 24% ginkgo flavone glycosides and 6% terpene lactones 80 mg* *Daily Value not established. Other ingredients: Cellulose, vegetarian capsule (hydroxypropyl methylcellulose, water), magnesium stearate, and silicon dioxide. GKB 90 vegetarian capsules TheraSleep™ For relief of occasional sleeplessness. The relaxing properties of three standardized botanicals are combined in one capsule intended for nighttime use. SUGGESTED USE: 1 to 2 capsules one hour before bedtime for the relief of occasional sleeplessness. Supplement Facts Amount Per Capsule 150 mg* 200 mg* 400 mg* *Daily Value not established. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), silicon dioxide, and magnesium stearate. SLP 60 vegetarian capsules Glycine Inhibitory neurotransmitter. Glycine is a unique compact amino acid essential for the structure of numerous body proteins, especially collagen. It is needed for the structure and function of hemoglobin and myoglobin and is an inhibitory neurotransmitter in the brain stem, spinal cord, and retina. It is also an obligate co-agonist for glutamate acting at the NMDA receptor. Glycine participates in processing motor and sensory information that permits movement, vision, and hearing. Each vegetarian capsule supplies 500 mg of glycine. SUGGESTED USE: 1 to 2 capsules daily with food. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, cellulose, and silicon dioxide. GLY 100 vegetarian capsules 500 250 100 250 100 100 mg* mg* mg* mg* mg* mg* 100 mg* 80 mg* 100 mg* 15 mg* 250 mg* Phosphatidylserine** 50 mg* *Daily Value not established. Other ingredients: Silicon dioxide, cellulose, stearic acid, carboxymethylcellulose sodium, magnesium stearate, and cellulose coating. **Sharp-PS® GREEN brand, a registered trademark of Enzymotec, Ltd. CONTAINS SOY. NRO 60 tablets Serving Size 1 Capsule Hops (Humulus lupulus) flower, dried 5:1 extract, min. 1% essential oil complex Passionflower (Passiflora incarnata) leaf, dried 5:1 extract, min. 3.5% vitexin Chamomile (Matricaria recutita) flower, dried extract, min. 1% apigenin Acetyl-L-Carnitine (as acetyl-L-carnitine hydrochloride) Glutamine (as L-glutamine USP) L-Pyroglutamic acid L-Tyrosine (as L-tyrosine USP) DMAE (dimethylaminoethanol) Ashwagandha (Withania somnifera), dried extract, min. 1.5% withanolides and 1% alkaloids Blueberry (Vaccinium corymbosum) fruit, min. 15% anthocyanins Ginkgo (Ginkgo biloba) leaf, dried extract, min. 24% ginkgo flavone glycosides and 6% terpene lactones Eleuthero (Eleutherococcus senticosus) root, dried extract, min. 0.8% eleutherosides Vinpocetine Glycerophosphocholine (GPC), supplying 50% alpha-glycerophosphocholine (from soy) NEURONUTRIENT FUNCTIONS Acetyl-L-Carnitine Glutamine L-Pyroglutamic acid L-Tyrosine DMAE Ashwagandha Extract Eleuthero Extract Blueberry Extract Ginkgo Extract Vinpocetine Phosphatidylserine Glycerophosphocholine Acetylcholine synthesis (memory), brain energy metabolism, membrane fluidity. Glutamic acid (neurostimulator) and GABA (calming neurotransmitter) precursor. Metabolism of acetylcholine-releasing nerve cells. Norepinephrine (long-term memory) and dopamine (muscle control) precursor. Promotes acetylcholine synthesis and reduces lipofuscin accumulation. Decreases cortisol release during stress. Improves stress response and cognitive function. Reduces oxidative stress in neuronal cells. Enhances flow of nutrients and oxygen to brain, regulates arterial tone. Glucose transport, antioxidant action, neurotransmitter release. Nerve cell structure, membrane fluidity, counterbalances stress hormones. Assists cell membrane function and promotes formation of acetylcholine. Phosphatidyl Serine Supports brain and nerve cell function. This natural phospholipid helps maintain function of brain and nerve cell membranes and activates neurotransmitters involved in learning and memory functions. Contains 100 mg of phosphatidylserine per softgel. SUGGESTED USE: 1 to 2 softgels daily with food. PHS 60 softgels Supplement Facts Serving Size 1 Softgel Amount Per Softgel Phospholipid Complex (from soy lecithin) 500 mg* Supplying approximately: Phosphatidylserine 100 mg* Phosphatidylcholine 25 mg* Phosphatidylethanolamine 2.5 mg* *Daily Value not established. Other ingredients: Gelatin, glycerin, polyglycitol syrup, and water. CONTAINS SOY. 33 Amino Acids L-Carnitine Taurine Heart and skeletal muscle contain abundant amounts of L-carnitine which is essential for meeting tissue energy demands by transporting fatty acids to the mitochondria. Normal endogenous production of L-carnitine can be inadequate in patients with kidney disease, diabetes, liver dysfunction, hyperlipidemias, and cardiac problems, thus requiring supplementation. These capsules contain 100% pure L-carnitine produced according to USP guidelines and are free of potentially harmful synthetic D-carnitine. Taurine helps regulate an unusual number of physiological processes including heart rhythm, contractile function, blood pressure, platelet function, osmotic pressure, visual cell function, bile acid synthesis, cholesterol degradation, and detoxification of xenobiotics. Its ability to help modulate calcium levels in cells, stabilize membranes, and restore antioxidant enzymes accounts for many of these actions. Supplies 500 mg pure, crystalline taurine. Supports cardiac and ocular function. Pure USP form. SUGGESTED USE: 1 to 6 capsules daily. CRN2 (250 mg) 60 vegetarian capsules Supplement Facts SUGGESTED USE: 1 to 3 capsules daily with food. Serving Size 1 Capsule Supplement Facts Amount Per Capsule L-Carnitine USP** 250 mg* Amount Per Capsule Other ingredients: Cellulose, vegetarian capsule (hydroxypropyl methylcellulose, water), silicon dioxide, and magnesium stearate. **Carnipure® brand, a licensed trademark of Lonza, Ltd. Used under license from Lonza, Ltd. Taurine USP L-Carnitine Tartrate Supplement Facts This more stable form of L-carnitine is less susceptible in a dry form to the effects of moisture than pure L-carnitine USP. Supplies 500 mg of elemental L-carnitine per capsule and is free of synthetic D-carnitine. SUGGESTED USE: 1 to 4 capsules daily. Amount Per Capsule L-Carnitine (as L-carnitine tartrate)** 500 mg* Serving Size 1 Capsule Amount Per Capsule Research on this acetylated derivative of L-carnitine has centered largely on its role in maintaining brain and nerve function during aging. The acetyl group can serve as a metabolic source of Supplement Facts acetylcholine, a brain neurotransmitter while the Serving Size 1 Capsule Amount Per Capsule L-carnitine component carries fatty acids into mitochondria of nerve, heart, and muscle cells for Acetyl-L-Carnitine (as acetyl-L-carnitine hydrochloride)** 500 mg* use in energy production. Other actions benefit *Daily Value not established. membrane stability, production of nerve growth Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), cellulose, L-leucine, and silicon dioxide. factor, and cerebral blood flow. Provided in its **Carnipure brand, a licensed trademark of Lonza, Ltd. Used under stable, hydrochloride form. license from Lonza, Ltd. ® SUGGESTED USE: 1 to 3 capsules daily. L-Lysine (as L-lysine hydrochloride USP) 500 mg* *Daily Value not established. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, silicon dioxide, and cellulose. LYS 100 vegetarian capsules L-Arginine Assists nitric oxide synthesis. Increased demands for L-arginine, a conditionallyessential amino acid, can occur during physical stress or illness. L-arginine supports growth hormone metabolism, tissue repair, energy metabolism, and nitric oxide synthesis. ALC3 30 vegetarian capsules ALC9 90 vegetarian capsules L-Tyrosine L-Glutamine Used for formation of T3 and T4 thyroid hormones, L-tyrosine is also an important precursor for brain-stimulating catecholamines (dopamine, noradrenaline, and adrenaline) which support stress response mechanisms and ability to concentrate. Supplies 500 mg of L-tyrosine USP per vegetarian capsule. L-glutamine is a primary energy source for intestinal immune cells and a major amino in muscle tissue. The body’s ability to produce adequate amounts may be compromised during physiological stress, thus warranting supplementation. SUGGESTED USE: 1 to 4 capsules daily between meals. Supplement Facts 34 One of the nine indispensable amino acids that must be obtained from food, L-lysine is a key player in enzyme production, collagen formation, and tissue repair. L-lysine intake may be inadequate in low protein diets. Supplement Facts Carnitine for the brain and nervous system. TYR (500 mg) 100 vegetarian capsules L-Lysine SUGGESTED USE: 1 to 6 capsules daily. Acetyl-L-Carnitine Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, cellulose, and silicon dioxide. *Daily Value not established. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), cellulose, and L-leucine. Essential amino acid. *Daily Value not established. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), carboxymethylcellulose sodium, silicon dioxide, and magnesium stearate. **Carnipure® brand, a licensed trademark of Lonza, Ltd. Used under license from Lonza, Ltd. CRN5 (500 mg) 60 vegetarian capsules Thyroid hormone precursor. 500 mg* TAU 100 vegetarian capsules Serving Size 1 Capsule Stabilized for longer shelf-life. Serving Size 1 Capsule *Daily Value not established. Key for muscle and GI function. SUGGESTED USE: 1 to 4 capsules daily between meals. SUGGESTED USE: 1 to 6 capsules daily. Supplement Facts Serving Size 1 Capsule Amount Per Capsule L-Arginine hydrochloride 700 mg* *Daily Value not established. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), cellulose, L-leucine, and silicon dioxide. ARG 100 vegetarian capsules Serving Size 1 Capsule Amount Per Capsule L-Glutamine USP 500 mg* *Daily Value not established. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, and cellulose. GLN 100 vegetarian capsules Vegetarian capsules made of plant cellulose are used for ProThera encapsulated products. Weight Management TheraSlim™ Whey Protein Pure, instantized whey protein isolate enriched with L-carnitine. A natural, non-stimulant adjunct for weight management programs. Whey protein is a complete protein of high biological value containing all the essential amino acids required in the daily diet. Whey protein isolate is the purest, most concentrated form of whey protein, containing over 90% protein and little to no fat, lactose, or cholesterol. An excellent protein choice for individuals of all ages, whey protein isolate is readily soluble, easily digested, and quickly absorbed. Whey protein is often a preferred source of protein for weight management as it activates satiety signals that affect both short-term and longterm regulation of food intake. It is also an excellent choice after bariatric surgery when obtaining adequate protein is often difficult. Protein insufficiency may contribute to hair loss, muscle loss, low energy, and poor skin tone. Other uses for whey protein isolate are sports nutrition, immune support, and general wellness. Derived from cow’s milk using a patented process that preserves bioactivity of whey proteins and other constituents such as lactoferrin and glycomacropeptides, this nondenatured, microfiltered whey protein isolate contains added L-carnitine to assist transport of long chain fatty acids across mitochondrial membranes for subsequent fat breakdown and energy production. The addition of L-carnitine enhances whey protein’s benefit in weight management. SUGGESTED USE: 1 to 2 scoops daily mixed in water or other beverage. Supplement Facts Serving Size 1 Scoop (Approx. 15.8 grams) • Servings Per Container 19 Amount Per Serving % Daily Value Calories Total Carbohydrate Protein Calcium Phosphorus Magnesium Sodium Potassium 55 <1 14 65 32 10 23 73 Whey Protein Microfiltered Isolate Typical Amino Acid Profile: L-Alanine 675 L-Arginine 260 L-Aspartic Acid 1,484 L-Cysteine 309 L-Glutamic Acid 2,370 Glycine 222 L-Histidine 231 L-Isoleucine 925 L-Leucine 1,416 L-Lysine 1,280 L-Methionine 273 L-Phenylalanine 425 L-Proline 875 L-Serine 610 L-Threonine 963 L-Tryptophan 223 L-Tyrosine 414 L-Valine 820 L-Carnitine (as L-carnitine tartrate) 15 g * 400 mg * * * * * * * * * * * * * * * * * * * g g mg mg mg mg mg mg mg mg mg mg mg mg mg mg mg mg mg mg mg mg mg mg mg < 1% 27% 7% 3% 3% < 1% 2% Carbohydrates are often maligned for those trying to lose weight. Yet, avoiding starchy foods is very difficult for many patients. Complex carbohydrates are an important nutritional component of a healthy diet that adds dietary fiber, B-vitamins, and trace elements. Diets too low in carbohydrates can depress serotonin levels and mood. Too often, patients resort to fatty or sugary foods to feel satiated. With TheraSlim™, patients can eat bread, pasta, rice, potatoes, and other complex carbohydrates as part of a balanced diet, yet limit their caloric contribution. TheraSlim™ contains Phase 2 Starch Neutralizer®, a natural, non-stimulant adjunct from the white kidney bean, Phaseolus vulgaris L., that may reduce the enzymatic digestion of dietary starches. Phase 2 Starch Neutralizer® is supported by a substantial body of competent and reliable scientific evidence, including 14 clinical Supplement Facts investigations. Two capsules Serving Size 2 Capsules of TheraSlim™ at least twice Amount Per 2 Capsules a day, taken with starchy Phase 2® white kidney bean 1,000 mg* meals or a snack, may assist (Phaseolus vulgaris L.), dried extract in weight control when used Fennel (Foeniculum vulgare) seed powder 500 mg* in conjunction with a sensible *Daily Value not established. diet and exercise program. SUGGESTED USE: 2 capsules with each meal. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), silicon dioxide, and magnesium stearate. SLM 90 vegetarian capsules Garcinia Cambogia Inhibits fat production. CitriMax® brand Garcinia cambogia standardized extract has been clinically shown to regulate appetite and inhibit fat production, without stimulating the central nervous system. SUGGESTED USE: 1 to 6 capsules daily before meals. **CitriMax® brand of (-) hydroxycitric acid. CitriMax® is a registered trademark of InterHealth N.I. Supplement Facts Serving Size 1 Capsule Amount Per Capsule Garcinia (Garcinia cambogia) fruit, dried extract, min. 50%(-) hydroxycitric acid** 500 mg* *Daily Value not established. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), cellulose, magnesium stearate, and silicon dioxide. GRC 100 vegetarian capsules TheraSlimPack™ Weight management program. Vitamins, minerals, and fatty acids important to sound nutrition and efficient fat burning and storage mechanisms are combined with the starch-neutralizing effects of Phase 2® in these convenient daily packets. SUGGESTED USE: 1 packet twice daily with food. Each packet contains: 3 MultiThera® 1 tablets • 2 TheraSlim™ capsules • 1 Conjugated Linoleic Acid softgel • 1 Garcinia Cambogia capsule. SLMP 30 packets Green Tea Extract 95% polyphenol content. Contains significantly higher amounts of epigallocatechin gallate (EGCG), the most active catechin (polyphenol), compared to most green tea extracts. Catechin polyphenols and other compounds in green tea act in synergy to promote fat oxidation and thermogenesis. SUGGESTED USE: 1 capsule twice daily with food. Supplement Facts Serving Size 1 Capsule Amount Per Capsule Green Tea (Camellia sinensis) leaf, dried extract, 750 mg* min. 40% epigallocatechin gallate, min. 95% poylphenols *Daily Value not established. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, and silicon dioxide. GTE 60 vegetarian capsules *Daily Value not established. Other ingredients: Lecithin from soy. CONTAINS MILK AND SOY. WHEY 10.58 oz. (300 grams) See pages 5, 29, and 35 for full ingredient information. 35 Adrenal Function Women’s Health EstroThera™ Adrenamin™ For hot flashes during menopause. Supports adrenal function. Botanicals that assist hormone balance and support capillary integrity often work well to control hot flashes and other uncomfortable symptoms experienced by women during menopause. EstroThera™ influences several mechanisms associated with hot flashes. Black cohosh, gamma-oryzanol, Norway spruce, and sage each have some success in clinical studies in minimizing menopausal symptoms, while hesperidin methylchalcone reduces oxidative stress and increases capillary Supplement Facts resilience to the stress Serving Size 1 Capsule of hormone fluctuations. Amount Per Capsule This product is free of Hesperidin Methylchalcone soy phytoestrogens. The ability of the adrenal gland to respond to physiological stress is supported by botanicals with recognized adaptogenic properties. Eleuthero and rhodiola act on neurotransmitter function, the central nervous system, and cardiovascular function to help the body adjust appropriately when faced with biological, physical, or chemical challenges. Cordyceps mushroom, known for its revitalizing effects, and pantothenic acid, a B-vitamin required for adrenal hormone formation, are also included. SUGGESTED USE: 1 capsule twice daily with food. EST 60 vegetarian capsules Gamma-Oryzanol (from rice bran oil) Black Cohosh (Cimicifuga racemosa) root and rhizome, dried extract, min. 2.5% triterpene glycosides, calculated as 27-deoxyactein Sage (Salvia officinalis) leaf Norway spruce (Picea abies) dried lignan extract containing hydroxymatairesinol** SUGGESTED USE: 1 to 2 capsules daily with food. 150 mg* 150 mg* 20 mg* 60 mg* 25 mg* *Daily Value not established. TheraVein Supports vascular integrity. Amount Per Capsule % Daily Value 1000% Cordyceps (Cordyceps sinensis) mycelia 400 mg * Eleuthero (Eleutherococcus senticosus) root, dried extract, min. 0.8% eleutherosides 200 mg * 50 mg * Rhodiola (Rhodiola rosea) root, dried extract, min. 5% rosavins *Daily Value not established. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, silicon dioxide, and cellulose. ADN 60 vegetarian capsules Signs of vascular weakness such as varicose veins, spider veins, hemorrhoids, and edema may result when structural integrity of blood vessels and capillaries is compromised. Botanicals that strengthen veins and capillaries, promote fluid balance, and assist blood flow can help support overall integrity and function of the venous system. More than a dozen clinical trials show that horse chestnut extract may guard against leg edema and capillary permeability. Butcher’s broom extract has significant toning effect on veins that eases the sensation of tired, heavy Supplement Facts legs. Gotu kola strengthens Serving Size 1 Capsule the microvascular Amount Per Capsule system and assists blood Horse Chestnut (Aesculus hippocastanum) seed, dried extract, 250 mg* flow while specific citrus min. 20% triperpene saponins, calculated as anhydrous aescin Gotu Kola (Centella asiatica) leaf, dried extract, min. 150 mg* bioflavonoids help stabilize 1% asiaticosides capillary fragility. This Butcher’s Broom (Ruscus aculeatus) root/rhizome, dried extract, 45 mg* synergistic formulation is min. 18% esterolic heterosides ideal for men or women Hesperidin Methylchalcone 125 mg* Citrus Bioflavonoid Complex, min. 50% flavonoids 125 mg* needing comprehensive vascular support. *Daily Value not established. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), silicon dioxide, and magnesium stearate. Serving Size 1 Capsule Pantothenic acid (as d-calcium pantothenate USP) 100 mg Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, and silicon dioxide. **HMRlignan™ brand, a trademark of Linnea SA ™ Supplement Facts SUGGESTED USE: 1 to 2 capsules daily. TVN 60 vegetarian capsules Ashwagandha Extract Rejuvenating Ayurvedic herb. Decreases cortisol release during stress. SUGGESTED USE: 1 capsule daily with food. Supplement Facts Serving Size 1 Capsule Amount Per Capsule Ashwagandha (Withania somnifera), dried extract, min. 1.5% withanolides and min. 1% alkaloids 300 mg* *Daily Value not established. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, cellulose, and silicon dioxide. ASW 60 vegetarian capsules Adrenal Cortex Natural glandular extract. This glandular extract contains the outer cortex section of bovine adrenal gland obtained from countries recognized to be BSE-free. The extract Supports bladder and urinary tract health with cranberry and berberine. is lyophilized (freeze-dried) to preserve Cranberine™ combines Cran-Max®** 100% whole cranberry fruit concentrate with berberine to biological activity. Contains 250 mg. provide broad supportive effects for the urogenital tract. Cran-Max® is made through a proprietary Supplement Facts Serving Size 1 Capsule process that intensifies the natural benefits of whole cranberry without the use of solvents, Amount Per Capsule preservatives or sugars. Biological activity is protected against stomach acid Adrenal Cortex Extract 250 mg* degradation with the patented Bio-Shield®** Supplement Facts system. Berberine, a plant alkaloid, provided *Daily Value not established. Serving Size 1 Capsule by berberine sulfate and Oregon Grape root, SUGGESTED USE: 1 capsule daily with food. Amount Per Capsule has anti-adherence activity against potential Other ingredients: Cellulose, gelatin capsule, water, silicon dioxide, Cranberry (Vaccinium macrocarpon) 500 mg* and magnesium stearate. whole fruit concentrate** urinary pathogens such as E. coli. Cranberine ™ Berberine Sulfate Oregon Grape (Mahonia aquifolium) root 100 mg* SUGGESTED USE: 1 to 2 capsules daily. 50 mg* **Cran-Max® brand. Cran-Max® and Bio-Shield® are registered trademarks of Bio-Nutra Technologies, LLC. *Daily Value not established. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, cellulose, and silicon dioxide. 36 CRAN 60 vegetarian capsules ADR 120 capsules (gelatin) Hormones DHEA Micronized for better absorption. Pure DHEA (dehydroepiandrosterone) that has been micronized to a very small particle size to facilitate absorption is provided in three potency options: 10 mg, 25 mg, and 50 mg. SUGGESTED USE: 1 to 2 capsules daily. Other ingredients: Cellulose, vegetarian capsule (hydroxypropyl methylcellulose, water), and magnesium stearate. DH1 (10 mg) 100 vegetarian capsules DH2 (25 mg) 100 vegetarian capsules DH5 (50 mg) 100 vegetarian capsules Pregnenolone Bioavailable, micronized form. Physiologically active pregnenolone, derived from natural diosgenin sterols, is micronized to a very small particle size to facilitate absorption. SUGGESTED USE: 1 to 2 capsules daily. Other ingredients: Cellulose, vegetarian capsule (hydroxypropyl methylcellulose, water), and magnesium stearate. PGN2 (25 mg) 100 vegetarian capsules Melatonin 3 mg vegetarian capsules. Melatonin’s role in maintaining normal sleep/wake cycles is well known. Supplemental melatonin is often needed to replace the body’s declining production that may occur with increasing age. SUGGESTED USE: 1 capsule one hour before bed. Other ingredients: Cellulose, vegetarian capsule (hydroxypropyl methylcellulose, water), and magnesium stearate. ML3 (3 mg) 60 vegetarian capsules Melatonin-SR Sustained-release formula. This sustained-release formulation delivers melatonin slowly over several hours to maintain blood levels for a longer period of time. SUGGESTED USE: 1 capsule one hour before bed. Other ingredients: Hydroxypropyl methylcellulose, vegetarian capsule (hydroxypropyl methylcellulose, water), and magnesium stearate. ML2 (2 mg sustained-release) 60 vegetarian capsules Melatonin-Lozenge Fast-dissolving 1 mg tablet. A quick-release formulation for fast action. Sweetened with mannitol and natural flavors. SUGGESTED USE: 1 tablet before bed. Other ingredients: Mannitol, vegetable stearine, silicon dioxide, citric acid, natural cherry flavor, carboxymethylcellulose sodium, and magnesium stearate. ML1 (1 mg) 60 tablets Men’s Health ProstaThera™ A multi-botanical and nutrient formula that supports prostate and urinary functions. Saw palmetto is highly useful for support of prostate function in adult men, and so are a number of other plant extracts and nutrients. Four botanical extracts with recognized roles in prostate health are combined in ProstaThera™ along with key trace elements and lycopene creating a highly beneficial prostate-support program. These ingredients influence testosterone metabolism and promote a favorable balance with dihydrotestosterone, help reduce an age-related decline in prostaglandin production, and help maintain normal cell and tissue functions. Cernitin® flower pollen extract contributes a unique, natural spectrum Supplement Facts of amino acids, Serving Size 1 Tablet carotenoids, Amount Per Tablet % Daily Value flavonoids, phytoCalcium (as tricalcium phosphate) 93 mg 9% sterols, nucleic acids, Phosphorus (as tricalcium phosphate) 48 mg 5% minerals, vitamins, Zinc (as zinc arginine chelate**) 5 mg 33% and enzymes and Selenium (as selenium amino acid complex) 50 mcg 71% has been shown in Copper (as copper bisglycinate chelate**) 0.5 mg 25% numerous clinical Saw Palmetto (Serenoa repens) fruit, dried extract, 356 mg * trials to be particularly min. 45% fatty acids and sterols (equivalent to 160 mg standardized to 85-95% fatty acid content) beneficial for prostate 50 mg * and urinary function. Pygeum (Pygeum africanum) bark, dried extract, SUGGESTED USE: 1 tablet twice daily with food. **Albion® Laboratories ***By authorization of Graminex/AB Cernelle. †Elemental lycopene content min. 2.5% total sterols calculated as -sitosterol Stinging Nettle (Urtica dioica) root, dried 4:1 extract Cernitin® Flower Pollen extract*** Lycopene 50 mg * 126 mg * 5 mg† * *Daily Value not established. Other ingredients: Silicon dioxide, cellulose, carboxymethylcellulose sodium, stearic acid, and cellulose coating. PRT 60 tablets ProstaThera™ Clinical Trial Results Clinical improvement in prostate and urinary functions was observed in 92% of men participating in a clinical study of ProstaThera™. Twenty-four men with benign prostatic hyperplasia (BPH), including five with chronic prostatitis, took one tablet twice daily for 12 weeks. Symptoms evaluated by American Urological Association Symptom Index (AUASI) scores showed noticeable improvement in the majority of subjects within 6 weeks with no adverse effects. Erner SI, Meiss DE. Open-label trial of a botanical/nutraceutical combination, ProstaThera™, on symptoms of benign prostatic hyperplasia (BPH) and prostatitis. In-house study 2003. ACTIONS OF PROSTATHERA™ INGREDIENTS Saw Palmetto Extract Pygeum Extract Stinging Nettle Extract Cernitin® Flower Pollen Extract Lycopene Zinc Arginate Selenium Copper ProRestore™ Improves urinary flow rate; inhibits 5-alpha reductase, thus decreases conversion of testosterone to DHT; reduces binding and transport of DHT by prostatic cells; enhances DHT elimination. Reduces androgen synthesis in prostate; regulates synthesis of inflammatory prostaglandins. Enhances urinary flow rate and decreases frequency of urination; may regulate prostatic cell growth. Reduces prostate volume and improves voiding difficulty by interrupting arachidonic acid cascade. Protects cells by quenching singlet oxygen. Reduces DHT and helps maintain prostate gland size. Supports normal cell health; antioxidant action. Needed for superoxide dismutase (SOD) antioxidant synthesis. Supplement Facts Supports energy metabolism with arginine and botanicals. Serving Size 2 Capsules L-Arginine hydrochloride 875 mg* Studies indicate a strong influence of nitric oxide in a wide range of reproductive functions. Need for L-arginine, a conditionally essential amino acid important for nitric oxide synthesis, growth hormone release, and energy metabolism, is increased during physical stress or illness. ProRestore™ combines significant amounts of L-arginine with ginseng, known for its ability to enhance energy metabolism, and other herbs. Maca (Lepidium meyenii) root, dried extract, min. 0.6% macamides and macaenes 125 mg* Asian Ginseng (Panax ginseng) root, dried extract, min 30% ginsenosides 125 mg* American Ginseng (Panax quinquefolius) root, dried extract, min 5% ginsenosides 125 mg* Muira puama (Ptychopetalum olacoides) root, 4:1 dried extract 125 mg* SUGGESTED USE: 2 capsules twice daily with food. PRO 120 vegetarian capsules Amount Per 2 Capsules Ginkgo (Ginkgo biloba) leaf, dried extract, min. 24% ginkgo flavone glycosides and 6% terpene lactones 40 mg* *Daily Value not established. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), silicon dioxide, and magnesium stearate. 37 Calcium and Magnesium OsteoThera™ OUR CHOICE FOR CALCIUM Build and maintain good bone health with a multifactorial approach. Inadequate calcium intake is a well-known risk factor for osteoporosis, a progressive bone disease influenced by age, sex, race, exercise, and many other dietary and lifestyle choices. OsteoThera™ is formulated with a two-fold purpose: 1) to help teenagers and young adult women optimize peak bone mass to reduce risk of osteoporosis later in life, and 2) to help slow the rate of bone loss in menopausal women, elderly men and women, and those with a family history of osteoporosis. Highly bioavailable forms of minerals essential for bone health plus synergistic nutrients are included to maximize mineral absorption using the least number of pills. Calcium and vitamin D support bone mineral density, magnesium supports bone strength and remodeling, boron promotes calcium and magnesium balance, and vitamin K activates proteins used in bone metabolism. When combined with average amounts of calcium and magnesium in the diet, two tablets or capsules twice daily taken with MultiThera® raises calcium and magnesium in a balanced manner to bring total amounts to recommended levels. SUGGESTED USE: 2 tablets or capsules twice daily with food. Calcium CitrateMalate High bioavailability. Supplement Facts A readily-soluble form of calcium that is equally well-absorbed with or without food. Taking calcium in several smaller doses throughout the day as supplied in these tablets produces higher absorption than taking a larger dose all at once. Serving Size 2 Tablets or 2 Capsules Amount Per 2 Tablets or 2 Capsules % Daily Value Vitamin D3 (as cholecalciferol) Vitamin K (50% as vitamin K1 phytonadione, 25% as vitamin K2 menaquinone-4, and 25% as vitamin K2 menaquinone-7) Calcium (as calcium citrate-malate) Magnesium (as magnesium bisglycinate chelate**) 250 mg 100 mg 25% 25% Boron (as boron aspartate-citrate) 0.5 mg * *Daily Value not established. There are many supplemental forms of calcium, including some very costly ones claiming superior benefit. We find that none are better documented than calcium citrate-malate, that is highly absorbable while simultaneously being safe, well-tolerated, and cost-effective. About 40% more calcium is absorbed from calcium citrate-malate compared to calcium carbonate or milk. We use calcium citrate-malate as the primary calcium source in MultiThera® formulas as well as in the bone support formulas shown here. 200 IU 50% 200 mcg 250% SUGGESTED USE: 1 to 4 tablets daily. Supplement Facts Serving Size 1 Tablet Amount Per Tablet **Albion® Laboratories Calcium (as calcium citrate-malate) Other ingredients: TABLETS: Cellulose, carboxymethylcellulose sodium, vegetable gum, stearic acid, silicon dioxide, magnesium stearate, and cellulose coating. CAPSULES: Vegetarian capsule (hydroxypropyl methylcellulose, water), cellulose, and L-leucine.. Added benefits for bone density. Studies with ipriflavone, an isoflavone-derivative, show it can enhance bone formation and inhibit bone breakdown. It is added to this OsteoThera™ formula for patients at highest risk of osteoporosis who are under regular clinical supervision. SUGGESTED USE: 2 tablets twice daily with food. OST2 120 tablets 25% Other ingredients: Cellulose, stearic acid, carboxymethylcellulose sodium, silicon dioxide, magnesium stearate, and cellulose coating. CCM 120 tablets OST1 120 tablets OSTC 120 vegetarian capsules OsteoThera™ Plus Ipriflavone % Daily Value 250 mg Calcium Citrate Powder Supplement Facts Serving Size 2 Tablets Amount Per 2 Tablets Vitamin D3 (as cholecalciferol) Vitamin K (50% as vitamin K1 phytonadione, 25% as vitamin K2 menaquinone-4, and 25% as vitamin K2 menaquinone-7 Calcium (as calcium citrate-malate) % Daily Value 200 IU 50% 200 mcg 250% 250 mg 25% Magnesium (as magnesium bisglycinate chelate**) 100 mg 25% Boron (as boron aspartate-citrate) 0.5 mg * Ipriflavone 300 mg * *Daily Value not established. Other ingredients: Cellulose, carboxymethylcellulose sodium, stearic acid, vegetable gum, silicon dioxide, magnesium stearate, cellulose coating, and zinc oxide. **Albion® Laboratories OsteoTheraPack™ Ultra-fine calcium citrate powder. Supplies calcium citrate, a readily-soluble, easyto-absorb form of calcium. Each heaping scoop contains 500 mg of pure calcium citrate with no added ingredients. SUGGESTED USE: 1 heaping scoop daily mixed with food or beverage. Supplement Facts Serving Size 1 Heaping Scoop (Approx. 2.5 g) Servings Per Container 120 Amount Per Serving Calcium (as calcium citrate) % Daily Value 500 mg 50% Other ingredients: None. CCP Net wt. 10.58 oz (300 grams) Combined support for bones and connective tissues. Obtaining synergistic benefits of key nutrients that help build and maintain bone and the underlying connective tissue matrix is easily accomplished with these convenient packets. SUGGESTED USE: 1 packet twice daily with food. Each packet contains: 3 MultiThera® 1 tablets • 2 OsteoThera™ Plus Ipriflavone tablets • 1 Glucosamine/ Chondroitin capsule. OSTP 30 packets See pages 5, 30, and 38 for full ingredient information. 38 Put your name on these packets or design your own. See page 45. Every batch of ProThera calcium supplements is independently tested to assure exceptionally low lead content in compliance with strict State of California Proposition 65 requirements. Calcium and Magnesium Chewable Calcium Magnesium Chelate Convenient wafer form. Easy-to-absorb, well-tolerated magnesium bisglycinate chelate. Well-absorbed calcium citrate and natural vitamin D3 are combined in these naturallyflavored, chewable tablet wafers. Equally suitable for children or adults. Often a preferred choice for gastric bypass patients. Magnesium’s benefits for enzyme activity, cardiac function, and energy metabolism are far reaching. As a required cofactor in more than 300 enzymes, magnesium plays a fundamental role in numerous cellular functions including energy production, skeletal and cardiac muscle excitability, neurochemical transmission, bone formation, insulin secretion, normal intracellular calcium, sodium and potassium levels, and the synthesis of carbohydrates, proteins, lipids, and nucleic acids. Albion’s amino acid chelate (magnesium bisglycinate chelate) is a highly absorbable and unusually well-tolerated form of magnesium. One of the prevalent pathways for magnesium absorption is via its formation of amino acid chelates which pass readily through the intestinal epithelium. The uptake of the Albion® magnesium amino acid chelate used in Magnesium Chelate is at least 1.8 times greater than magnesium carbonate, 2.6 times greater than magnesium sulfate, and 4.1 times greater than magnesium oxide. This is likely due to its low molecular weight and size which allows it to be readily absorbed without dissociation and binding to a carrier. And, unlike many forms of magnesium such as magnesium sulfate, magnesium oxide, and magnesium carbonate that commonly cause digestive disturbances including diarrhea, Albion’s magnesium bisglycinate chelate rarely causes adverse side effects. Albion’s unique manufacturing process produces a true chelate in which the mineral and amino acid form a unique three-dimensional structure which protects the mineral compound from unwanted interactions Supplement Facts during digestion yielding a highly bioavailable, Serving Size 1 Capsule Amount Per Capsule % Daily Value natural absorptive form of magnesium that is readily and comfortably assimilated. Magnesium (as magnesium bisglycinate 150 mg 38% SUGGESTED USE: 1 to 4 tablets daily. Supplement Facts Serving Size 1 Tablet Amount Per Tablet Total Carbohydrates Sugars % Daily Value <1 g <1 g <1%† * Vitamin D3 (as cholecalciferol) 100 IU 25% Calcium (as calcium citrate) 250 mg 25% †Percent Daily Values are based on a 2,000 calorie diet. *Daily Value not established. Other ingredients: Fructose, honey, lecithin (from soy), vegetable stearine, natural orange and pineapple flavor, magnesium stearate, and citric acid. CONTAINS SOY. CHC 120 chewable tablets Chewable Cal-Mag Plus D Bioavailable calcium and magnesium plus vitamin D. Calcium and magnesium citrates are supplied in a 2:1 ratio with natural vitamin D3 in convenient chewable wafers. Magnesium complements calcium and vitamin D by supporting bone strength and remodeling. It is also vital for energy production and proper cardiovascular function. SUGGESTED USE: 1 to 2 capsules daily with food. MAG 100 vegetarian capsules chelate*) Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water) and L-leucine. *Albion® Laboratories SUGGESTED USE: 2 to 4 tablets daily with food. Cal-Mag 2:1 Plus D Supplement Facts Bioavailable calcium and magnesium combination. Serving Size 2 Tablets Amount Per 2 Tablets Calories Total Carbohydrates Sugars Vitamin D3 (as cholecalciferol) Calcium (as calcium citrate) Magnesium (as magnesium citrate) % Daily Value 5 2 2 100 250 125 g g IU mg mg <1%† * 25% 25% 31% †Percent Daily Values are based on a 2,000 calorie diet. *Daily Value not established. Other ingredients: Fructose, honey, lecithin (from soy), vegetable stearine, natural orange and pineapple flavor, magnesium stearate, and citric acid. CONTAINS SOY. CHCM 120 tablets Calcium, magnesium, and vitamin D are each essential for healthy bone formation. Calcium and vitamin D support bone mineral density while magnesium supports bone strength and remodeling. Cal-Mag 2:1 Plus D supplies calcium citrate, a highly absorbable, well-tolerated source of calcium, balanced with magnesium in a 2:1 ratio. Magnesium bisglycinate chelate from Albion® Laboratories provides highly Supplement Facts absorbable magnesium that is unusually Serving Size 2 Tablets well-tolerated without GI side effects. Natural Amount Per 2 Tablets % Daily Value vitamin D3 assists calcium absorption to Vitamin D3 (as cholecalciferol) 100 IU 25% enhance benefits for bone health. May be used Calcium (as calcium citrate) 250 mg 25% ® with MultiThera multiple vitamin/mineral Magnesium (as magnesium bisglycinate 125 mg 31% chelate*) supplements to augment calcium, magnesium, and vitamin D intake when necessary. Other ingredients: Vegetable gum, carboxymethylcellulose sodium, SUGGESTED USE: 2 to 4 tablets daily with food. CAL 120 tablets cellulose, stearic acid, silicon dioxide, magnesium stearate, zinc oxide, and cellulose coating. *Albion® Laboratories Also Available From Klaire Labs® Magnesium Citrate Order ProThera and Klaire Labs products TOLL-FREE 7:30 AM • 5 PM Pacific time 888-488-2488 Vegetarian capsule provides 150 mg of readily-soluble magnesium citrate per capsule. Powder option supplies 300 mg magnesium citrate per scoop. V433-09 90 vegetarian capsules K-MGP 10.58 oz (300 g) powder To request a Klaire Labs® catalog call 888-488-2488. 39 Minerals and Trace Elements Strontium Iron Chelate Bioavailable citrate form, 300 mg. Strontium is a mineral element important for the normal structure and function of the skeletal system. Nearly all strontium in the body occurs in bones, teeth, and connective tissue. Strontium supports strength of hydroxyapatite crystals in calcified tissues such as bones and teeth. Clinical studies show it supports bone metabolism by stimulating new bone formation and decreasing bone resorption. Strontium citrate is a stable, non-radioactive form of strontium that can be used as a dietary supplement to support bones, teeth, and collagen. Supplement Facts Serving Size 1 Capsule Amount Per Capsule Strontium (as strontium citrate) 300 mg* *Daily Value not established. SUGGESTED USE: 1 to 2 capsules daily with or between meals, away from calcium-containing food or supplements. Bioavailable bisglycinate chelate from Albion® Labs. This exceptionally well-tolerated form of iron is produced through a special process that completely bonds iron to two glycine amino acids forming iron bisglycinate, a well-absorbed form of this essential mineral. Studies show ferrous bisglycinate is better absorbed than ferrous sulfate, ferrous gluconate, and other common inorganic forms of iron. Supplies 30 mg elemental iron per capsule. SUGGESTED USE: 1 capsule daily with food. Supplement Facts Serving Size 1 Capsule Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, cellulose, and silicon dioxide. Amount Per Capsule Iron (as Ferrochel® ferrous bisglycinate chelate)* STR 100 vegetarian capsules % Daily Value 30 mg Other ingredients: Cellulose, vegetarian capsule (hydroxypropyl methylcellulose, water), magnesium stearate, and silicon dioxide. *Albion® Laboratories IRN30 100 vegetarian capsules Strontium Forté Dual action benefits on bone and cartilage metabolism. Strontium Forté combines the bone-supportive benefits of strontium with those of Perluxan®, a unique extract of hops cones that exerts numerous effects on regulation of proinflammatory compounds affecting bone metabolism. These ingredients support the body’s ability to naturally balance bone formation and bone resorption by activating osteoblasts and decreasing the number of osteoclasts. Osteoblasts are bone cells that form and maintain bone and cartilage, while osteoclasts remove minerals from bones. Alpha acids in hops inhibit inflammatory mediators, including prostaglandin E2 that can stimulate osteoclasts Supplement Facts and cause bone loss and tissue discomfort. Serving Size 1 Capsule ® Perluxan is free of phytoestrogenic and sleep inducing compounds normally found in hops. Amount Per Capsule SUGGESTED USE: 1 capsule twice daily with or between meals, away from calcium-containing food or supplements. Up to 4 capsules daily may be used for maximum support. Strontium (as strontium citrate) 125 mg* Perluxan® Hops (Humulus lupulus L.) cones, dried extract containing alpha and iso-alpha acids 500 mg* *Daily Value not established. STRF 90 vegetarian capsules Other ingredients: Cellulose, vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, and silicon dioxide. SelenoPlex™ Zinc Chelate Chewable Iron Chelate Bioavailable Albion® trisglycinate chelate in convenient chewable. This convenient chewable tablet option contains an exceptionally well-tolerated and taste-free form of iron produced by attaching iron to three glycine amino acids forming iron trisglycinate, a wellabsorbed form of this essential mineral. Supplies 30 mg of elemental iron. Natural cherry flavor. SUGGESTED USE: 1 tablet daily with food. Supplement Facts Selenium in two important forms. Bioavailable Albion® chelate. Serving Size 1 Tablet A special process completely bonds zinc to the amino acid glycine forming zinc bisglycinate, a well-absorbed form of this essential mineral. Supplies 20 mg elemental zinc as zinc bisglycinate chelate*. Amount Per Tablet SUGGESTED USE: 1 tablet daily with food. SUGGESTED USE: 1 tablet daily with food. †Percent Daily Values are based on a 2,000 calorie diet. *Daily Value not established. Supplement Facts Supplement Facts Selenium, an essential trace element important for antioxidant enzyme activity, is provided as selenomethionine, a bioavailable storage form, and as sodium selenate, a readily available active form. Each offers distinctive benefits. Serving Size 1 Tablet Amount Per Tablet Selenium (50% as L-selenomethionine and 50% as sodium selenate) Serving Size 1 Tablet % Daily Value 200 mcg 286% Other ingredients: Cellulose, stearic acid, silicon dioxide, magnesium stearate, carboxymethylcellulose sodium, and cellulose coating. SEL 100 tablets 40 167% Amount Per Tablet Zinc (as zinc bisglycinate chelate)* % Daily Value 20 mg 133% Other ingredients: Cellulose, stearic acid, silicon dioxide, carboxymethylcellulose sodium, magnesium stearate, and cellulose coating. *Albion® Laboratories ZNC 100 tablets Calories Total Carbohydrates Sugars Iron (as ferric trisglycinate chelate)** % Daily Value 5 2g 2g 30 mg <1%† * 167% Other ingredients: Fructose, dextrates, silicon dioxide, natural cherry flavor, vegetable stearine, and magnesium stearate. **Albion® Laboratories IRN-CH 100 tablets Minerals and Trace Elements Iodine Complex MultiMinerals Mineral-only blend. Supplies a balanced mix of essential minerals and trace elements for situations that may call for minerals without added vitamins or other nutrients. Contains similar amounts and sources as MultiThera® multiple vitamin/mineral formulas, including Albion’s amino acid chelates, calcium citrate-malate, L-selenomethionine, and other well-utilized forms. SUGGESTED USE: 4 tablets daily with food. Supplement Facts Serving Size 4 Tablets Amount Per 4 Tablets % Daily Value Calcium (as calcium citrate-malate) Iodine (from kelp) Magnesium (as magnesium bisglycinate chelate**) Zinc (as zinc bisglycinate chelate**) Selenium (as L-selenomethionine) Copper (as copper bisglycinate chelate**) Manganese (as manganese bisglycinate chelate**) Chromium (as chromium nicotinate glycinate chelate**) Molybdenum (as molybdenum glycinate chelate**) Potassium (as potassium aspartate) 400 mg 40% 150 mcg 100% 400 mg 100% 15 mg 200 mcg 2 mg 2 mg 200 mcg 150 mcg 99 mg 100% 286% 100% 100% 167% 200% 3% Boron (as boron aspartate-citrate) Vanadium (as bisglycinato oxovanadium) 2 mg 100 mcg * * High-potency iodine/iodide. Essential for formation of thyroid hormones, iodine’s benefits for immune function are less well appreciated. Higher intakes such as those consumed in the Japanese diet may be required to achieve whole body sufficiency. Growing evidence suggests that RDI levels of iodine of 150 mcg daily, while beneficial for thyroid function, may be far too low to support the needs of other organs throughout the body. Instead, milligram amounts, as well as different forms of iodine, may be required to maintain normal cell integrity and optimum function of the mammary glands, gastric mucosa, thymus, and numerous other tissues that also concentrate iodine. To help achieve iodine sufficiency, ProThera® Iodine Complex is formulated with inorganic iodine in three beneficial forms, molecular iodine, potassium iodide, and sodium iodide and provided in a choice of potencies, 6.25 mg (6,250 mcg) or 12.5 mg (12,500 mcg). Our vegetarian capsule formulation avoids the gastric irritation and unpleasant taste as may occur with liquid forms of iodine. Iodine Complex (6.25 mg) Iodine Complex (12.5 mg) Supplement Facts Supplement Facts Serving Size 1 Capsule Serving Size 1 Capsule Amount Per Capsule % Daily Value Iodine (2.5 mg as molecular iodine, 2.5 mg as sodium iodide, and 1.25 mg as potassium iodide) 6.25 mg 4167% Amount Per Capsule % Daily Value Iodine (5 mg as molecular iodine, 5 mg as sodium iodide, and 2.5 mg as potassium iodide 12.5 mg 8333% *Daily Value not established. Other ingredients: Carboxymethylcellulose sodium, cellulose, vegetable gum, silicon dioxide, stearic acid, magnesium stearate, and cellulose coating. **Albion® Laboratories Other ingredients: Cellulose, vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, and silicon dioxide. Other ingredients: Cellulose, vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, and silicon dioxide. SUGGESTED USE: 1 to 2 capsules daily with food. SUGGESTED USE: 1 capsule daily with food. IDN6 90 vegetarian capsules IDN 90 vegetarian capsules IDN180 180 vegetarian capsules MMN 120 tablets ChromeMate® A safe and bioavailable form of chromium. Also Available From Klaire Labs® Chromium Picolinate Plus Vegetarian capsule providing 100 mcg of chromium bound to picolinic acid. V122-10 100 vegetarian capsules Seleno Met™ Vegetarian capsule providing 200 mcg of L-selenomethionine form of selenium. V127-10 100 vegetarian capsules To request a Klaire Labs® catalog call 888-488-2488. ChromeMate® is a patented, niacin-bound form of the essential mineral chromium shown to efficiently support blood sugar and lipid metabolism. This unique polynicotinate complex has superior bioavailability and biological activity compared to inorganic forms of chromium, such as chromium chloride. Chromium plays an essential role in maintaining glucose homeostasis. By potentiating the action of insulin at the receptor site, chromium facilitates cellular uptake of glucose. Chromium also plays a role in normal lipid metabolism by supporting normal LDL and HDL levels. And, along with a healthy diet and lifestyle, chromium may increase fat loss and help to preserve lean body mass. ChromeMate® is recommended for persons who want a superior, highly bioavailable form of chromium for nutritional support of blood Supplement Facts glucose metabolism, Serving Size 1 Tablet lipid metabolism, and Amount Per Tablet % Daily Value weight management. Chromium 200 mcg 167% Scored tablets. (as chromium polynicotinate)* Other ingredients: Cellulose, silicon dioxide, stearic acid, magnesium stearate, carboxymethylcellulose sodium, and cellulose coating. *ChromeMate® brand InterHealth N.I. SUGGESTED USE: 1 tablet daily with food. CHR 100 tablets Order ProThera and Klaire Labs products TOLL-FREE 7:30 AM • 5 PM Pacific time 888-488-2488 41 Skin Health DermaThera™ Regenerin™ Daily Rejuvenating nutrients for the skin. Helps protect skin tissue from damaging influences and aging. DermaThera™ supports healthy skin condition and combats damaging influences in several important ways. Glucosamine sulfate and methylsulfonylmethane (MSM®) supply bioavailable sulfur compounds to help form healthy, resilient connective tissues. Alpha-lipoic acid and L-carnosine are potent antioxidants that protect cells and tissues from free radical damage throughout the body, including the skin. Both alpha-lipoic acid and L-carnosine have the added benefit of inhibiting glycation, a major Supplement Facts cause of skin aging. SUGGESTED USE: 1 to 2 capsules daily with food. Serving Size 1 Capsule Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), cellulose, magnesium stearate, and silicon dioxide. **MSM® is the registered trademark for licensed methylsulfonylmethane, a naturally-occurring source of sulfur, an essential mineral. Alpha-Lipoic Acid Regenerin™ Daily provides daily nutritional protection to help maintain healthy collagen and combat free radicals that can damage cells and cause premature skin aging. Useful for post-surgical or non-surgical patients who wish to maintain skin health on an ongoing basis. SUGGESTED USE: 1 packet twice daily with food. Each packet contains: • 1 VitaPrime® tablet • 1 OmegaThera™ softgel • 1 DermaThera™ capsule Amount Per Capsule 50 mg* L-Carnosine 250 mg* Glucosamine Sulfate.2KCl (from crab and/or shrimp shells) 250 mg* RGND 60 packets Methylsulfonylmethane (MSM®**) See pages 7, 29, and 42 for full ingredient information. 250 mg* *Daily Value not established. Oral Care DRM 60 vegetarian capsules DermaHydrate™ Enhances hyaluronic acid production and moisture content of skin. Mucopolysaccharides such as hyaluronic acid and chondroitin sulfate play a major role in maintaining moisture balance and resilience of collagen and skin tissues. Damage and loss of collagen, elastin, and hyaluronic acid during aging or poor diet can result in reduced elasticity, rough texture, and fine wrinkles. While oral ingestion of hyaluronic acid, chondroitin sulfate, and collagen can help support skin condition, these high molecular weight compounds require digestion into smaller units for absorption to occur. To avoid uncertain digestibility, DermaHydrate™ combines two oral nutritional agents that are rapidly absorbed from the intestine and promote biosynthesis of collagen and hyaluronic acid. Both have been clinically shown to encourage firmer and smoother skin. L-hydroxyproline is a primary amino acid constituent of collagen, connective tissue, and elastin that helps stabilize the 3-D structure of collagen. It enhances proliferation of epidermal cells and promotes formation of the basal layer. In an 8-week clinical study, L-hydroxyproline had a positive effect on moisture retention, elasticity, and softness of skin. N-acetyl-D-glucosamine (NAG) is an amino Supplement Facts sugar needed to form hyaluronic acid in the Serving Size 1 Capsule dermis. DermaHydrate™ contains naturallyAmount Per Capsule derived NAG shown in an 8-week clinical study L-Hydroxyproline** 250 mg* of women with dry, rough skin to increase N-Acetyl-D-Glucosamine*** 250 mg* moisture content and improve skin smoothness. (from crab and/or shrimp shells) SUGGESTED USE: 1 capsule twice daily with food. *Daily Value not established. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), cellulose, silicon dioxide, and L-leucine. **Lumistor™ brand, a trademark of Kyowa Hakko Kogyo Co., Ltd. ***Hyalurogluco™ brand, a trademark of Kaneka Nutrients, LP DHY 60 vegetarian capsules L-Carnosine Hyaluronic Acid Potent tissue-protecting agent. L-Carnosine is a natural dipeptide compound that supports healthy cell function by two important mechanisms. It protects cells against free radical damage and inhibits protein glycation, a major cause of accelerated aging of brain, skin, and other body tissues. SUGGESTED USE: 1 to 2 capsules daily between meals. Supplement Facts Supplement Facts Hyaluronic acid powder, min. 9% hyaluronic acid 500 mg* *Daily Value not established. Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), cellulose, silicon dioxide, and magnesium stearate. 42 SUGGESTED USE: 6 softgels daily with food for 14 days followed by 1 softgel twice daily thereafter. Amount Per Softgel Amount Per Capsule CAR 90 vegetarian capsules Hyaluronic acid helps maintain fluid balance in cells producing a moisturizing effect on the skin. Contains low molecular weight hyaluronic acid for enhanced absorption. Serving Size 1 Softgel Serving Size 1 Capsule L-Carnosine Natural hydrating agent. 70 mg* *Daily Value not established. Other ingredients: Rice bran oil, gelatin, glycerin, water, yellow beeswax, and titanium dioxide. HYA 120 softgels Folazin™ Oral rinse with folic acid and zinc. This nutrient-containing oral rinse allows folic acid and other nutrients to be applied topically to gingival tissues. Folazin™ is designed for daily use as part of a total oral hygiene program to help maintain healthier gums — an important component of a healthy immune and cardiovascular system that helps protect against entry of undesirable bacteria into the bloodstream. Each capful (1 teaspoon) contains 5 mg of folic acid. Free of alcohol, artificial flavorings, colorings, and sweeteners. SUGGESTED USE: Use twice daily. INGREDIENTS: Deionized water, sorbitol, potassium sorbate, natural mint flavor, sodium ascorbate (vitamin C), zinc, aloe vera, folic acid, sodium bicarbonate, and chlorophyll. FOL 8 fluid oz About Klaire Labs® Our Specialty: Innovative Probiotics, Prebiotics, and Enzymes The Klaire Labs® product line offers an extensive selection of hypoallergenic, dairy-free probiotics, prebiotics, and enzymes designed to assist gastrointestinal health, support detoxification processes, and regulate immune system functions. A significant focus of ProThera’s technical staff is to support clinical research into the benefits of probiotics and related nutritional agents for GI and immune health and reflect those efforts though continued development of unique Klaire Labs® brand nutraceuticals and educational opportunities. Certified Dairy-Free Probiotics: Probiotics are beneficial living microorganisms that support healthy gastrointestinal and immune systems. Because clinical effectiveness of probiotic organisms is dependent on many variables, Klaire Labs’ probiotic quality assurance commitment consists of an aggressive, independent testing program that monitors and ensures the identity, activity, and hypoallergenicity of our finished products. Our probiotics are guaranteed to be free of common allergens, including gluten and dairy proteins. Prebiotic Formulas for GI and Immune Benefits: Prebiotics are specific types of soluble dietary fiber that selectively support growth of beneficial intestinal bacteria. Prebiotics can enhance probiotic effectiveness, support immune balance, and encourage growth of healthy flora indigenous to the GI tract. Klaire Labs® offers several unique prebiotic formulas to augment GI support. Special Enzymes for Gluten and Casein Digestion: Digestion-resistant, proline-rich peptides found in gluten (from wheat and other grains) and casein (dairy protein) can be especially problematic and may exert opioid-like (exorphin) activity in the central nervous system in susceptible individuals. Dipeptidyl peptidase IV (DPP-IV) enzyme expressed on intestinal brush border membranes is responsible for cleaving proline-rich peptides. ProThera® holds four US patents for proprietary enzyme compositions with DPP-IV activity designed to support hydrolysis of exorphins peptides. Klaire Labs® SerenAid®, Vital-Zymes® Complete, and Vital-Zymes® Chewable enzyme supplements provide DPP-IV activity to hydrolyze casein, gluten, and other small peptides, thus enhancing digestion of a full-range of plant and animal proteins. Patent-Pending Antibiofilm Formulas: Biofilm consists of microorganisms encased within a selfproduced matrix that strongly adheres to interfaces and resists dislodgement. ProThera’s Chief Science Officer, Stephen Olmstead, MD, whose involvement in researching biofilms spans over a decade, developed Klaire Labs® patent-pending InterFase® and InterFase Plus® specialty enzyme supplements with documented antibiofilm activity that disrupt the biofilm matrix that embeds potential GI pathogens. ProThera’s Klaire Labs® Division: Serving Healthcare Professionals For More Than 40 Years. Since 1969, Klaire Labs® has been a recognized and favored brand of health professionals seeking nutritional support for individuals with severe food allergies and environmental sensitivities. Klaire Labs®, under the direction of its founder Claire Farr, developed some of the very first hypoallergenic nutritional supplements available, making Klaire Labs® an innovator in dairy-free probiotics and vegetarian enzymes for gastrointestinal support. In 2004, Klaire Labs® was acquired by ProThera®, Inc. expanding the company’s offerings of nutraceutical formulations with unique probiotics, enzymes, and other specialty products. Rather than redefining the products under the ProThera® brand, the highly-respected Klaire Labs® brand name and label identity was retained. Today, ProThera® maintains a commitment to product purity and hypoallergenicity for both the Klaire Labs® and ProThera® brands of nutraceutical products. All products in both product lines are gluten-free. They are also dairy-free with the exception of one product (Whey Protein) in the ProThera® line. No artificial sweeteners, flavors, colors, or preservatives are used. The Klaire Labs® product line includes an extensive selection of products for intestinal health, immune system regulation, and support of the specialized nutritional needs of individuals with autism spectrum disorders (ASD) and other neurodevelopmental concerns. As with ProThera® products, Klaire Labs® products are provided exclusively to health professionals and their authorized patients. The Klaire Labs® product line includes: • Hypoallergenic Probiotics • Prebiotic Dietary Fiber • Vegetarian Digestive Enzymes • Antibiofilm Enzymes • P-5-P and other Vitamins • Minerals and Trace Elements • Amino Acids • Specialty Nutrients ProThera® and Klaire Labs® products are available directly from ProThera, Inc. and are shipped together from our Reno, NV headquarters. To request a catalog describing Klaire Labs® dietary supplements, call 888-488-2488 or visit our websites www.klaire.com or www.protherainc.com. 43 Custom Packaging and Formulation Private Labeling Customized labels at no extra charge for as few as 12 bottles per product. An increasing number of healthcare professionals are using private labeling to help maintain more frequent contact with patients and improve compliance. Your name on a product label is a daily reminder to patients as well as their family and friends that they can rely on you as their source for quality supplements. Easy access to your recommended products can help avoid substitution by patients of inappropriate or substandard products, thus reinforcing your goals for their health. Our exceptionally low minimum private label order requirement of only 12 bottles per product allows you to create your own brand of products without a huge upfront investment. We will include your name and contact information on the label of any ProThera® or Klaire Labs® product at no additional cost. All we need is a few days notice. Select from one of our pre-designed private label templates and submit your personalized logo or trademark for inclusion on the label if you wish. Our regular wholesale pricing and volume discounts will apply to your order. A fast and affordable way to establish your own brand of products ProThera offers quick and easy private labeling and custom formulation services to help extend recognition of your practice on a daily basis. Our customized services personalize dietary supplements by putting your name and address on the label. Your customized label can be applied to any of our existing products or packet combinations in a few days time, or to a new formula that is uniquely your own. Even our combination supplement packs show your name and phone number on each packet and on the bottle at no extra cost. Use our product name or choose one of your own to further distinguish your product. Whether you are new to private labeling or already have an existing line that you wish to modify, ProThera makes the entire process simple and convenient. Private-Label Ordering Process 1. Select products to private label 2. Choose a private label design 3. Phone or fax your order request Private Label ProThera and Klaire Labs products TOLL-FREE 7:30 AM • 5 PM Pacific time 888-488-2488 44 • Add your name to a custom label for any ProThera or Klaire Labs product • Only 12 bottle minimum order needed* • Fast 2-day turnaround time • No extra charge for the service • Regular volume discounts apply *Sold in case increments (12 bottles per case) Your private label... 12 bottles... 2 days... guaranteed! Custom Packaging and Formulation Choose a private-label design Select from a Template: Our graphic artists have created a variety of designer labels to provide a professional appearance to your nutraceutical products. Choose the one you like and we will have your product ready to ship within two days of your approval – fully labeled at no extra charge. Each design gives you flexibility to further customize your label by modifying colors or adding your logo. These designs provide plenty of room to add your complete name, address, and other contact information. Or, Provide Your Own Design: If you prefer, we can also work with you to create a special label design to match your office stationary or other specifications. Simply provide an electronic file of your personalized design or logo and we’ll do the rest. Because we want to ensure that you are 100% satisfied with your customized label design, processing on custom designs may take a bit longer. Personalized Supplement Packs Improve patient compliance and promote your practice with your own supplement packet combinations. This convenient service lets you combine various ProThera and Klaire Labs products into one cellophane packet, thus accomplishing several goals at once. It eliminates patient confusion over how many of each separate supplement to take, making it easier to stay on their supplement program either at home or away. And, since this specific nutrient combination can’t be found elsewhere, patients will contact your office for refills. Each bottle and each individual packet is labeled with your name, address, and phone number, giving you an effective way to advertise at no added cost. Your personalized supplement packets will cost no more than the equivalent price of the individual product contents. Our fast 2 day turnaround, low minimum order requirement (12 bottles per product), and coordinated approach to product formulation make this a flexible, cost-effective service that offers many benefits to your practice. • Create supplement combinations unique to your practice • Enhance patient convenience and results • Put your name and phone number on each packet • Only 12 bottle minimum order needed OPTION 1 OPTION 2 • Simple to order, fast 2-day turnaround • No extra charge for the service YOUR NAME HERE REQUEST A QUOTATION Receiving a price quotation for your custom supplement packets is as easy as picking up the phone. We will quote you a price over the phone in only a few minutes time and help you adjust the combination of products as needed to achieve your clinical goals. OPTION 3 OPTION 4 ProThera Packs also available for private labeling Each of the combination packets shown throughout our catalog can be packaged with your name on the label in quantities as low as 12 bottles. The chart below summarizes the contents of each product. OPTION 5 Pack Packet Contents AntioxTheraPack™ 3 MultiThera® 1 tablets, 1 Vitamin C tablet, 1 CoEnzyme Q10 (60 mg) softgel, 1 Glutathiol™ capsule ArthroTheraPack™ 3 MultiThera® 1 tablets, 2 ArthroThera™ tablets, 2 OsteoThera™ tablets, 1 Marine Fish Oil softgel CardioTheraPack™ 3 MultiThera® 1 tablets, 1 CardioThera™ capsule, 1 InflaThera™ capsule, 1 Hawthorn Extract capsule GlucoTheraPack™ 3 MultiThera® 1 tablets, 1 GlucoThera™ capsule, 1 Alpha-Lipoic Acid tablet, 1 Marine Fish Oil softgel OPTION 6 GlucoThera™ Forté Pack 3 MultiThera® 1 tablets, 2 GlucoThera™ Forté capsules, 1 Marine Fish Oil softgel InflaTheraPack™ 3 MultiThera® 1 tablets, 2 OmegaThera™ softgels, 2 Quercetin-Bromelain Forte™ tablets, 1 InflaThera™ capsule OsteoTheraPack™ 3 MultiThera® 1 tablets, 2 OsteoThera™ Plus Ipriflavone tablets, 1 Glucosamine/Chondroitin capsule Regenerin™ Daily 1 VitaPrime® tablet, 1 OmegaThera™ softgel, 1 DermaThera™ capsule TheraSlimPack™ 3 MultiThera® 1 tablets, 2 TheraSlim™ capsules, 1 Conjugated Linoleic Acid (CLA) softgel, 1 Garcinia Cambogia capsule 45 Custom Packaging and Formulation Creating Patient-Specific Programs Manufacturing Overview The body’s metabolic network is a complex, interconnected system. The same holds true for nutrients — each serves numerous physiological functions that are interwoven with the actions of other nutrients. Research continually confirms that nutrients, unlike drugs, don’t work alone. Maximum benefit and safety in using nutritional supplements as therapeutic adjuncts is best achieved by maintaining a global perspective of their synergistic as well as potential antagonistic interactions. By using MultiThera® as the cornerstone of each patient’s nutritional program, specific health concerns can be more completely addressed with various ProThera combination nutrient products. Each formula easily coordinates with MultiThera® and addresses related areas of metabolic function as described below. Products may be purchased individually as needed or combined together in convenient cellophane packets at no extra charge (see page 45). Active B Cmpl™ ArthroThera™ CardioThera™ EstroThera™ GastroThera™ Gliatrol™ GlucoThera™ Glutathiol™ HepatoThera™ InflaThera™ MitoThera™ Myalgesin® NeuroThera™ OcuThera™ OmegaThera™ OsteoThera™ ProRestore™ ProstaThera™ Quercetin/Broml SAMe 200 Serralase™ Strontium Forté Thera-B™ TheraDophilus™ TheraFlavone™ TheraSlim™ TheraVein™ 46 Bone Health Brain/Nervous System Capillary Integrity Cardiovascular Cholesterol Metabolism Energy Metabolism Gastrointestinal Health Glucose Metabolism Homocysteine Hormone Balance Immune Function Inflammation Joint/Connective Tissue Liver Function Ocular Health Prostate Function Weight Management MultiThera® Antioxidant Protection Product Function Cross-Reference Guide X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X PAGE 5-6 11 30 19 36 21 31 15 14 25 31 17 30 33 14 29 38 37 37 23 32 23 40 10 21 13 35 36 ProThera nutraceuticals are produced in licensed manufacturing facilities that strictly adhere to current Good Manufacturing Practices (cGMPs). Products provided in tablet, capsule, and powder form are made in a manufacturing facility licensed by the State of California as a drug manufacturer and food processor and registered with the Food and Drug Administration as a drug manufacturing establishment. The facility is also approved by governmental agencies in the United Kingdom and the European Community (EC) to manufacture a drug product. Current GMPs and written standard operating procedures (SOPs) are strictly followed through all stages of production to produce products that meet or exceed United States Pharmacopeia (USP) standards. Raw Material Specifications Active ingredients in ProThera products are selected based on purity, bioavailability, documented actions, and safety characteristics. Materials meeting USP standards are used for those nutrients where this standard exists. Raw materials are purchased exclusively from reputable vendors who provide detailed Certificates of Analysis for every lot of material. These certificates certify that active components, toxic elements, and microbial content are within specified acceptable parameters. Purity and potency of all raw materials are verified through independent testing laboratories by raw material vendors and ProThera, Inc. All incoming raw materials undergo quarantine, inspection, evaluation, and identity testing by infrared spectroscopy. Purity and potency of all raw materials are verified through independent testing laboratories. Raw material vendors and third-party labs are routinely inspected by on-site audits for quality compliance by ProThera quality assurance personnel. Quality Control Laboratory Testing On-site laboratory personnel evaluate physical characteristics of each finished product including hardness, disintegration, moisture balance, friability, and pH. Purity and potency of finished product is independently verified through outside commercial laboratories using a randomized ingredient and batch testing program. Excipients ProThera products are free of artificial flavors, preservatives, and colorings. Naturally-derived, inert materials, including cellulose-based excipients, vegetable-derived magnesium stearate, L-leucine, and silicon dioxide are used in very small amounts as tableting and encapsulation aids. Tablets are protected with an inert, water-soluble cellulose coating that dissolves readily upon ingestion, thus facilitating disintegration time. Vegetarian capsules made of plant cellulose are used exclusively for ProThera’s two-piece encapsulated products. Common allergens such as wheat, soy, yeast, and dairy are avoided unless otherwise specified in our ingredient listings. Custom Packaging and Formulation Custom Formulation Formulation Assistance Manufacturing services for your exclusive formulas. Dennis Meiss, PhD If you would like a product or ingredient not found in our catalog, don’t hesitate to ask. We gladly accommodate requests for manufacturing special formulas in tablets, capsules, softgels, chewable wafers, or powder form. When you need a certain mixture of nutrients to best implement your nutritional protocols, this service may be your most effective option. We will manufacture your product using the same attention to detail we give to our own. Your finished product can be private labeled in the way you prefer or even provided in bulk form for packaging elsewhere. Minimum quantities as low as 25,000 capsules or 50,000 tablets are often possible depending on the formulation, and we always do our best to offer highly competitive pricing. Dr. Dennis Meiss provides formulation insights and recommendations to help you create an effective product. Some nutrients are incompatible when mixed together or simply won’t fit into the number of tablets or capsules desired. Dr. Meiss will advise you of the options that best suit your specific concerns and answer any questions you may have. Tablet Preparations Tablets are often the most flexible delivery form option. Adjustable tablet sizes accommodate higher amounts of nutrients compared to fixed capsule fill volumes. Contrary to popular belief, tablets do not necessarily contain more excipients than capsules. Properly made tablets use a minimum of excipients and break down as well as or even faster than capsules. The ability to tightly control tablet disintegration times can offer distinct advantages for bioavailability of certain nutrients. ProThera’s manufacturing expertise encompasses the following tablet options: As primary formulator and director of ProThera’s technical support programs, Dr. Meiss draws on over 20 years experience in creating medically-oriented nutraceuticals and working with physicians in both the dietary supplement and clinical laboratory testing industries. Dr. Meiss holds a doctorate in neurobiology from the University of Connecticut and earned research appointments at the University of Toronto and Boston University. He was assistant professor of physiology at Clark University prior to joining the natural products industry. Water-soluble tablet coating technology Encapsulated Products Unlike most tablet manufacturers that utilize corn protein (zein) or food glaze (lacquer) coatings that many people find undesirable, ProThera applies an inert, cellulose-based water-soluble coating to protect ingredients from oxidation and create a smooth surface that makes our tablets easy to swallow. This coating dissolves readily upon ingestion and facilitates desirable disintegration times. Two-piece capsules are a popular choice and ProThera can formulate your product using either vegetarian capsules or regular gelatin capsules. While vegetarian capsules are a bit more costly, they have wide appeal for those with strict dietary preferences. As with our tableted formulas, each batch of capsules is tested to ensure appropriate disintegration using official USP protocols. Chewable wafers Chewable tablets are often the preferred choice for children and those who cannot easily swallow regular tablets or capsules. Our manufacturing chemists have many years of experience making palatable chewables that contain all-natural sweeteners and flavors. Fast-dissolving tablets Some nutrients are suitable for quick release and ProThera can easily accommodate these requests. Powdered Formulas Amino acid mixtures, protein supplements, dietary fiber blends, and vitamin C drink mixes are examples of formulations that work well in powder form. We can work with you to create the blend that fits your purpose. Enteric-coated tablets Softgel Capsules Certain ingredients require protection from stomach acid to retain maximum potency and bioavailability. We may recommend this specialized technology for some formulations where appropriate. Oil-soluble nutrients are frequently best suited for encapsulation in soft gelatin capsules. ProThera can facilitate manufacture of custom softgels through reputable suppliers to ensure you receive a quality product. Larger minimum order requirements of approximately 300,000 softgels are typically required for this process. Controlled-release tablets When slow-release of ingredients is desired, our manufacturing processes can provide for extended disintegration times within USP guidelines. Full-disclosure Labeling Order custom products and packets TOLL-FREE 7:30 AM • 5 PM Pacific time 888-488-2488 Product labels are in full compliance with U.S. Food and Drug Administration labeling regulations and include a full listing of ingredients contained in each product. Ingredients are expressed as elemental content to reflect the actual active amounts present. Botanical ingredients are standardized to active marker compounds wherever possible and labeling specifies the percent composition of these compounds in the extract. Product Packaging Tamper-resistant inner safety seals and full bottle outer plastic sleeves are applied to each bottle. All products are expiration dated to indicate freshness. ProThera products have a shelf-life of at least 24 months from date of manufacture at full label potency. Individual supplement packets are hermetically sealed in cellophane utilizing pharmaceutical compliant packaging equipment certified ISO 9002. 47 Supplement Packs AntioxTheraPack™ Comprehensive nutritional programs in easy-to-use packets A potent antioxidant supplement program. The specific combination of nutrients contained in these convenient packets has been used in clinical practice for many years to support cardiovascular health and immune function through the synergistic action of antioxidants that depend on each other for maximum effectiveness. Antioxidants exert their fullest protective benefits through a series of related actions called the antioxidant cascade. AntioxTheraPack™ supplies significant amounts of key nutritional antioxidants and cofactors that activate antioxidant pathways and help protective cellular mechanisms operate at high efficiency. SUGGESTED USE: 1 packet twice daily with meals. Each packet contains: 3 MultiThera® 1 tablets A strong antioxidant foundation, including vitamins C, E, and natural beta-carotene; zinc, copper, and manganese to activate superoxide dismutase (SOD); and selenium and B-vitamins to keep glutathione enzymes active. 1 Vitamin C (1,000 mg) tablet Extra ascorbic acid to help regenerate vitamin E. 1 CoEnzyme Q10 (60 mg) softgel Pure CoQ10 with vitamin E (60 IU) to support heart energy metabolism and the immune system. 1 Glutathiol™ capsule Glutathione (50 mg), NAC (300 mg), and taurine (500 mg) to enhance liver detoxification mechanisms. ATP 30 packets See pages 5, 11, 12, 14, and 16 for full ingredient information. GlucoTheraPack™ ArthroTheraPack™ Full-spectrum micronutrient support for diabetics. Supports joint tissues from many directions. Connective tissue structure and function and regulation of inflammatory processes are influenced by many nutritional factors, including a healthy fatty acid balance, a plentiful supply of cartilage precursors, antioxidant levels, and mineral nutrition. ArthroTheraPack™ contains a broad-array of nutrients to support each of these needs. SUGGESTED USE: 1 packet twice daily with food. Each packet contains: 3 MultiThera® 1 tablets Supplies vitamins and minerals such as vitamin C and manganese that support connective tissue function. 2 ArthroThera™ tablets Contains glucosamine and chondroitin, building blocks of connective and joint structures, plus bromelain enzyme and Devil’s Claw herb to help support the body’s natural inflammatory response. 2 OsteoThera™ tablets Provides extra calcium and magnesium for bone health. 1 Marine Fish Oil softgel Omega-3 fatty acids support immune function and inflammatory regulation mechanisms. These convenient daily packets provide intensive support for glucose and insulin metabolism, cardiovascular health, nerve function, and other special nutrient needs of patients with impaired glucose tolerance. SUGGESTED USE: 1 packet twice daily with food. Each packet contains: 3 MultiThera® 1 tablets Supplies chromium, manganese, B-vitamins, and other nutrients needed for glucose metabolism. 1 GlucoThera™ capsule Supports glucose metabolism and helps protect against damaging effects of protein glycation by supplying extra chromium and biotin, plus alphalipoic acid, N-acetyl-L-cysteine, and two botanicals. 1 Alpha-Lipoic Acid tablet Supplies an additional 100 mg of this antioxidant, bringing total alpha-lipoic acid to 250 mg per packet. 1 Marine Fish Oil softgel Omega-3 fatty acids for the immune system. ARTP 30 packets See pages 5, 26, 30, and 38 for full ingredient information. 48 The various combination supplement packets shown throughout this catalog and summarized here are created for patients who might need a specific combination of nutrients targeted to more specific health concerns. Each of our convenient packet programs contains MultiThera® 1 Iron-Free multiple vitamin/mineral supplements to first form a sound nutritional platform of 30 essential nutrients. MultiThera® offers wideranging benefit for cellular antioxidant protection, cardiovascular function, nervous system, homocysteine regulation, visual function, bone health, connective tissues, glucose regulation, immune system, and other organ functions. These benefits are then augmented with the addition of other ProThera products that supply concentrated amounts of specific nutrients with documented roles in the area of clinical focus. The need for separate bottles of individual supplements is reduced or even eliminated, and patient confusion over how many of each different product to take is no longer a problem. Each of our combination packets are formulated into two packets daily. Just one packet taken twice daily makes it easy for patients to stay on their recommended supplement program. GLCP 30 packets GLCP60 60 packets See pages 5, 15, and 26 for full ingredient information. Supplement Packs InflaTheraPack™ Helps regulate inflammation. Combines nutrients, fatty acids, botanicals and enzymes for comprehensive benefit. SUGGESTED USE: 1 packet twice daily with food. Each packet contains: 3 MultiThera® 1 tablets Antioxidant nutrients protect against tissue damage. 1 InflaThera™ capsule Multibotanical actions modulate COX enzymes. 2 OmegaThera™ softgels Fatty acid precursors of anti-inflammatory eicosanoids. 2 Quercetin/Bromelain Forté™ tablets Enzymes to help ensure proper protein breakdown. INFP 30 packets See pages 5, 23, 29, and 31 for full ingredient information. CardioTheraPack™ A broad-array of cardiosupportive nutrients, including those that help regulate inflammatory responses. This specialized supplement pack combination pulls together four ProThera products that support cardiovascular function in complementary ways. Included are key nutrients and botanicals that address inflammatory mechanisms, homocysteine metabolism, energy pathways, cholesterol and lipid metabolism, regulation of coronary blood flow, and essential nutrient needs. SUGGESTED USE: 1 packet daily with food or as directed by healthcare practitioner. Each packet contains: 3 MultiThera® 1 tablets Supplies vitamin E, magnesium, selenium, folate and other vitamins and minerals that support cardiac function and homocysteine metabolism. 1 CardioThera™ capsule Provides extra folate and B12 for homocysteine regulation, carnitine for energy production in the heart, policosanol to support cholesterol metabolism, and resveratrol for potent antioxidant action. 1 InflaThera™ capsule Includes herbal extracts that help modulate COX enzymes and help regulate inflammatory responses throughout the body. 1 Hawthorn Extract capsule Supports blood flow to the heart, key to maintaining normal blood pressure. CRDP 30 packets Customized Supplement Packs Specially Formulated by Healthcare Professionals ProThera works closely with healthcare professionals who wish to create customized supplement packs for certain types of patients based on their own clinical experience. Specific combinations of ProThera products can be packaged together as needed to address different patient needs and provide added convenience in taking the recommended nutrients. TheraSlimPack™ OsteoTheraPack™ Weight management program. Combined support for bones and connective tissues. Vitamins, minerals, and fatty acids important to sound nutrition and efficient fat burning are combined with Phase 2® carbohydrate neutralizer and Garcinia herb. SUGGESTED USE: 1 packet twice daily with food. Each packet contains : 3 MultiThera® 1 tablets Supplies B-vitamins, magnesium, chromium, and other energy-support nutrients important for efficient calorie burning. 2 TheraSlim™ capsules Provides Phase 2® plant extract to reduce the amount of calories absorbed from starchy foods. 1 Conjugated Linoleic Acid softgel Assists fat burning and storage mechanisms. 1 Garcinia Cambogia capsule Helps regulate appetite and limit fat production. SLMP 30 packets See pages 5, 29, and 35 for full ingredient information. Order ProThera and Klaire Labs products TOLL-FREE 7:30 AM • 5 PM Pacific time See pages 5, 18, 19, and 31 for complete ingredient information. Obtaining synergistic benefits of key nutrients that help build and maintain bone and the underlying connective tissue matrix is easily accomplished with these convenient packets. Total daily amounts of important bone supportive minerals and vitamins provided by two packets daily include: 1,000 mg calcium, 700 mg magnesium, and 1,400 IU vitamin D. SUGGESTED USE: 1 packet twice daily with food. Each packet contains : 3 MultiThera® 1 tablets Supplies calcium, magnesium, vitamin D, vitamin K, boron and other bone-support nutrients. 2 OsteoThera™ Plus Ipriflavone tablets Adds extra amounts of calcium and other key nutrients, plus ipriflavone (300 mg). 1 Glucosamine/Chondroitin capsule Support connective tissues and bone matrix with 500 mg glucosamine sulfate and 400 mg chondroitin sulfate. OSTP 30 packets See pages 5, 30, and 38 for full ingredient information. 888-488-2488 49 INDEX 5-adenosylcobalamin, 4-8, 11 5-HTP (5-hydroxytryptophan), 32 5-LOXIN®, 30 5-lipoxygenase, 30 5-MTHF, see L-5-MTHF AC-11®, 20, 24 acacia senegal, 21 Acetyl-L-Carnitine, 17, 33, 34 acid protease, 22 Active B Complex™, 11 Active B12-Folate, 9 Active B Trio™, 9 Adrenal Cortex, 36 adrenal function, 4, 10, 36 Adrenamin™, 36 aging, 16, 20, 31, 33, 42 alpha-galactosidase, 22 Alpha-Lipoic Acid, 14, 15, 17, 25, 42 amino acids, 14, 32-35, 42-45 amylase, 22-23 antioxidants, 4-25, 31, 33-37, 40-42 AntioxTheraPack™, 18, 48 appetite control, 32, 35 artemisia, 20 ArthroThera™, 30 ArthroTheraPack™, 30, 48 ascorbic acid. See vitamin C Asian ginseng extract, 37 Ashwagandha Extract, 33, 36 astragalus, 23 B-complex vitamins, 4-11. See also supplement packs banaba leaf extract, 15 barberry extract, 20, 31 Benfotiamine, 8, 10, 11 Berberine, 14, 20, 31, 36 beta-carotene, 4-8. See also supplement packs beta-cryptoxanthin, 4-8, 12 beta-glucan, 24 Beta-Q Immune™, 24 betaine, 10, 19, 25 Betaine HCl, 22 bifidobacterium, 21 bilberry extract, 13-14 Biotin, 4-8, 10, 11, 15 bisglycinato oxovanadium, 5-8 black cohosh extract, 36 blood pressure, 18 blood sugar, 15. See also glucose metabolism blueberry extract, 31, 33 bone health, 4, 38-40 Borage Oil, 28, 29 boron, 5-8, 38, 41. See also supplement packs boswellia serrata, 30 brain function, 4, 16, 32-34 broccoli extract, 24 bromelain, 23, 30 butcher’s broom extract, 36 calcium, 4-8, 38-39, 41. See also supplement packs Calcium Citrate-Malate, 4-8, 38 Calcium Citrate Powder, 38 Calcium D-Glucarate, 25 Cal-Mag 2:1 Plus D, 39 calcium undecylenate, 20 capillary integrity, 4, 12-14, 36 CardioThera™, 19 CardioTheraPack™, 19, 49 cardiovascular support, 4, 9-13, 16-19, 26-27, 36 catalase, 23 celery seed extract, 30 cellulase, 22, 24 Cernitin® flower pollen extract, 37 chamomile extract, 33 Chewable Calcium, 39 Chewable Cal-Mag Plus D, 39 Chewable CoEnzyme Q10 (150 mg, 300 mg), 16 Chewable Iron Chelate, 40 Chinese skullcap extract, 31 chlorella, 24 cholesterol/lipid metabolism, 4, 13, 15, 19, 26-29, 34 choline, see B-complex vitamins chondroitin sulfate, 30 ChromeMate®, 5-8, 15, 41 50 ProThera® products are highlighted in bold chromium, 5-8, 15, 41. See also supplement packs Cinnamon Extract, 15 CitriFlavone™, 12 CitriMax®, 35 citrus bioflavonoids, 5-8, 12-13, 36 CoEnzyme Q10 (30, 60, 100, and 200 mg), 16, 17 Conjugated Linoleic Acid (CLA), 29 connective tissue, 4, 12-13, 30-31, 34, 40, 42 copper, 5-8, 37, 41. See also supplement packs Coptis extract, 20, 31 CoQH™, 16 cordyceps, 36 COX-1 and COX-2, 31 Cranberine™, 36 cranberry concentrate, 36 Cran-Max®, 36 creatine monohydrate, 17 curcuminoids, 15, 30, 31 goldenseal extract, 23 gotu kola extract, 36 Grape Extract, 13, 14, 17 Green Tea Extract, 13, 20, 31, 35 griffonia seed extract, 32 gum arabic, 21 gymnema extract, 15 d-alpha tocopherol, 4-8, 11, 14 D-Chiro-Inositol, 14 D-Ribose, 18 Deparex™, 20 DermaHydrate™, 42 DermaThera™, 42 detoxification, 14, 24-25, 30, 34 devil’s claw extract, 30 DHA (docosahexaenoic acid), 26-27, 29 DHEA (10, 25, & 50 mg), 37 diabetes, 10, 15, 34 DIM (diindolylmethane), 25 DMAE (dimethylaminoethanol), 33 DNA repair, 20, 24 Dual Detox™, 24 immune function, 4, 13, 20-21, 23-24, 26-29, 40 ImmunoThera™, 24 Indole Forté™, 25 inflammation, 13, 20, 23-24, 26-31, 40 InflaThera™, 31 InflaTheraPack™, 31, 49 inositol, 5-10, 32 Inositone™, 32 inulin, 21 iodine, 4-8, 41. See also supplement packs Iodine Complex, 41 ipriflavone, 38 iron, 5, 8, 40 Iron Chelate, 40 Hawthorn Extract, 18 HepatoThera™, 25 HepatoThera™ Forté, 25 hesperidin methylchalcone, 5-8, 12, 36 holy basil extract, 31 homocysteine regulation, 4, 9-10, 19 hops extract, 33, 40 horse chestnut extract, 36 hot flashes, 36 Hyaluronic Acid, 42 joint function, 13, 30-31 echinacea extract, 23 Eicosamax®, 27 eleuthero extract, 33, 36 endorphin regulation, 34 EPA (eicosapentaenoic acid), 26-27, 29 energy metabolism, 4, 15-18, 30, 34 enzyme activity, 22-24, 30, 40 EstroThera™, 36 Ester-C® / Ester-C® Bio, 12, 42 E-Tocotrienol™, 11 European elder, 23 Evening Primrose Oil, 28 fatty acids, 26-29 fennel, 21, 35 Ferrochel®, 5, 8, 40 feverfew extract, 32 fiber, soluble, 21 fibrinolytic activity, 23 fibromyalgia, 30 fish oil, 15, 26-27, 29-31, 42 flavonoids, 4-8, 12-14, 17, 25, 33, 35-37 Flax Seed Oil, 28, 29 FloraGLO® lutein, 12, 14 folate, 4-11, 19, 42 Folazin™, 42 folic acid, see folate GABA (gamma-aminobutyric acid), 32 GABA Plus, 32 gamma-oryzanol, 36 Garcinia Cambogia, 35 gastrointestinal function, 20-21 GastroThera™, 21 Ginkgo Biloba, 13, 33, 37 ginger extract, 31 gingival tissues, 42 ginseng extract, 37 Gliatrol™, 31 Glucosamine/Chondroitin, 30, 38 Glucosamine Sulfate, 30, 42 glucose metabolism, 4, 15 GlucoThera™, 15 GlucoThera™ Forté, 15 GlucoThera™ Forté Pack, 15 GlucoTheraPack™, 15, 48 Glutathiol™, 14, 18, 42 glycation, 10, 15, 42 Glycine, 32, 33 glycerophosphocholine (GPC), 33 L-5-MTHF (L-5-methyltetrahydrofolate), 4-11, 19. See also supplement packs L-Arginine, 34, 37, 42 L-Carnitine, 19, 34, 35 L-Carnitine Tartrate, 34 L-Carnosine, 42 L-cysteine, 14, 25 L-Glutamine, 21, 33, 34 L-glutathione, 14, 18 L-hydroxyproline, 42 L-leucine, 35 L-Lysine, 34 L-Methionine, 25 L-MethylFolate, 9 L-pyroglutamic acid, 33 L-Theanine, 32 L-Tyrosine, 33, 34 lactobacillus microorganisms, 21 larch arabinogalactan, 24 Lecithin, 16-17, 19, 31 licorice extract, 23 lipase, 22-23 liver function, 13, 24-25 Lutein, 4-8, 12, 14 luteolin, 31 LutiMax®, 31 lycopene, 37 lymph/lymphatic function, 12, 23 maca extract, 37 Mag-Potassium Aspartate, 18 magnesium, 4-8, 17-18, 22-23, 38-39, 41. See also supplement packs Magnesium Chelate, 39 Malic Acid, 17, 18 manganese, 4-8, 41. See also supplement packs Marine Fish Oil, 15, 26, 27, 30, 42 Melatonin (1, 2 & 3 mg), 37 melatonin production, 32 mental function, 33 men’s health, 5, 37 Meriva®, 30, 31 Metafolin®, 4-11, 19 Methyl-B12 Lozenge, 9 Methyl Balance™, 10 methylcobalamin, 4-11, 19. See also suppl. packs methylsulfonylmethane (MSM®), 30, 42 MigraThera™, 32 milk thistle extract, 13, 25 INDEX mitochondria, 16-17, 34 MitoThera™, 17 mixed tocopherols, 4-8, 11 molybdenum, 4-8, 30, 41. See also supplement packs mood regulation, 26-27, 32 MSM® 750, 30 muira puama extract, 37 MultiMinerals, 41 MultiThera® 1 Iron-Free, 5. See also suppl. packs MultiThera® 1 Capsule Formula Iron-Free, 6 muscle function, 30 MultiThera® 2 Plus Iron, 5 MultiThera® 3 Iron- and Copper-Free, 6 Myalgesin®, 30 N-acetyl-D-glucosamine, 21, 42 N-Acetyl-L-Cysteine, 14, 15, 17, 25 Nattokinase-NSK-SD®, 23 Nexrutine®, 30 nerve function, 4, 15, 33-34 NeuroThera™, 33 niacin/niacinamide, 4-8, 10, 11. See also suppl. packs Niacin-SR, 19 Norway spruce, 36 ocular health, 14. See also visual function OcuThera™, 14 olive leaf extract, 23 omega-3/omega-6, 26-29 Omega-3 Mini™, 26 OmegaThera™, 29, 42 oral care, 42 Oregon grape root, 36 OsteoThera™, 38 OsteoThera™ Plus Ipriflavone, 38 OsteoTheraPack™, 38, 49 PABA, see para-Aminobenzoic acid pancreatin, 22-23 Pantothenic Acid, 4-8, 10, 11, 36. See also suppl. packs papain, 23 para-Aminobenzoic acid, 5-8, 10. See also suppl. packs passionflower extract, 33 Perluxan® hops extract, 40 Phase 2®, 35 phellodendron extract, 30 phosphatidylcholine, 17, 19, 33 Phosphatidyl Serine, 33 pine bark extract, 13 platelet function, 13, 19, 33 Policosanol, 19 polygonum cuspidatum extract, 12, 19, 31 potassium, 4-6, 18, 41. See also supplement packs prebiotics, 21 Pregnenolone (25 mg), 37 private labeling, 44-45 probiotics, 21 ProRestore™, 37 prostate function, 37 ProstaThera™, 37 Protectagen™, 20 protease, 22-24 proteolytic enzymes, 22-23 pTeroPure™, 31 pterostilbene, 31 Pycnogenol®, 12, 13 pygeum extract, 37 pyridoxal 5’-phosphate, 8, 10, 11 Quercetin-Bromelain Forté™, 23, 31 quercetin, 12, 17, 23, 24 Regenerin™ Daily, 42 Resveragen™, 12 resveratrol, 12-14, 19, 31 rhodiola extract, 36 riboflavin, 4-8, 10, 11, 32. See also suppl. packs riboflavin 5’-phosphate, 8, 10, 11 rosemary extract, 31 rutin, 12, 23, 31 sage, 36 SAMe 200, 32 saw palmetto extract, 37 selenium, 4-8, 25, 37, 40-41. See also suppl. packs selenomethionine, 5-6, 41 SelenoPlex™, 40 serotonin, 32 Serralase™, 23 Serratia peptidase, 23 Sharp-PS® GREEN, 33 skin and hair nutrition, 10, 26-29, 42 sleep, 33 sodium succinate, 17 sorbic acid, 20 SpectraFiber™, 21 stinging nettle extract, 37 stress, 32-33, 36 Strontium, 40 Strontium Forté, 40 sulfur, 14, 30, 42 Suntheanine®, 32 supplement packs, 15, 18-19, 30-31, 35, 38, 42 surgical support, 8, 42 Taurine, 14, 18, 25, 32, 34 Thera-B™, 10 TheraDophilus™, 21 TheraFlavone™, 13 TheraGest™, 22 TheraSleep™, 33 TheraSlim™, 35 TheraSlimPack™, 35, 49 TheraVein™, 36 thiamine, 4-8, 10-11. See also supplement packs thyroid function, 4, 34 tocopherol, 5-8, 11, 18 tocotrienol, 11 trimethylglycine (betaine), 10, 19, 25 Turmeric 250, 30 Turmeric 500, 31 turmeric extract, 15, 30, 31 ubiquinol/ubiquinone, 16-17 uncaria tomentosa extract, 20, 24 Undecylex™, 20 urinary tract, 36-37 HOW TO ORDER Call toll-free 888-488-2488 Speak with us directly between 7:30 a.m. and 5 p.m. Pacific time. Voice messages left after hours are returned the next business day. Fax 775-850-8810 Order anytime. Download form online upon login to your account. Mail your order to ProThera, Inc. 10439 Double R Blvd, Reno, NV 89521 Online Go to www.protherainc.com or scan this code with your phone to place secure orders on our Website upon login. Terms of Distribution ProThera® and Klaire Labs® products are sold under the condition that they not be resold in retail outlets or on the Internet except under a renamed private label. Our Guarantee Unopened bottles of ProThera® and Klaire Labs® products, excluding probiotics, may be returned for any reason for a full refund or exchange within 30 days of purchase. Please call prior to returning to let us know your preference. V-Nzyme Blend™, 22 vanadium, 4-8, 15, 41. See also supplement packs vanadyl sulfate, 15 vascular function, 18-19, 36 veins, 36 vinpocetine, 33 ViraThera CF™, 23 visual function, 4, 13-15, 34 VitalActiv®, 8 Vitamin A, 4-8, 11. See also supplement packs vitamin B6, 4-11. See also supplement packs vitamin B12, 4-11, 19. See also supplement packs Vitamin C, 4-8, 12, 14, 23. See also suppl. packs Vitamin D3, 4-8, 11, 38-39. See also suppl. packs Vitamin E, 4-8, 11, 14. See also suppl. packs vitamin K, 4-8, 11, 38. See also supplement packs Vitamin K2, 4-6, 11, 38. See also suppl. packs VitaPrime®, 7, 42 VitaTab® Chewable, 8 weight loss surgery, 8, 35 weight management, 35 Whey Protein Plus L-Carnitine, 35 women’s health, 5, 36, 38-40 wormwood, 20 wound healing, 23, 34, 42 yeast, 20, 24 zeaxanthin, 4-8, 12, 14. See also supplement packs zinc, 4-8, 37, 40, 42. See also supplement packs Zinc Chelate, 40, 41 Statements made herein have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, or cure any disease. ©Copyright 2002-2013 ProThera®, Inc., Reno, NV. All rights reserved. 51 10439 Double R Blvd. Reno, NV 89521 Contact ProThera® Toll-Free 888-488-2488 Main 775-850-8800 Fax 775-850-8810 www.protherainc.com NEW PRODUCTS INSIDE. . . . VitaPrime® Capsule Formula – Two-per-day multiple, p7 Active B Complex™ – With bioactive B vitamin forms, p11 Berberine – Glucose metabolism support from berberine HCl, p14 Beta-Q Immune™ – Beta-glucan and quercetin, p24 Turmeric 500 – Bioavailable Meriva® turmeric phytosome p31 Integrated Nutraceutical Formulations • Uniquely designed to avoid nutrient redundancy between multi-ingredient products • Produced under strict cGMP standards in a drug manufacturing facility • Exclusive to licensed healthcare professionals Private Labeling & Manufacturing Services • Personalized labels at no extra charge for as few as 12 bottles per product • Supplement packets with nutrients of your choice • Custom manufacturing also available 8<TCIAFE=bdfdhr>6