סולטיף הדור החדש של קולרים נגד קרציות לכלבים

MOSCOW OCTOBER 2013
Special presentation for
• General managers
• Veterinarians
• Sales men
Company Profile
Solano develops and manufactures innovative parasite control products for pets. The
company was founded in 2002 and is headquartered in the Beth She’an Valley.
The founder of the company, Amnon Vardi completed his study at the Technion
Institute as a Chemical Engineer. He enjoys a reputation in various fields in the industry,
and is responsible for several unique developments, both in Israel and abroad.
Solano’s company values stress the importance of innovation, product quality &
effectiveness, safety, dedicated customer service, reliability and high standards, while
striving to meet the needs of clients, employees and partners alike. Giving back to the
community is another valued principle at Solano.
Company activity: Based on the aforementioned values, Solano offers its clients an
effective and safe parasite control for pets. Our company works tirelessly to develop
groundbreaking products, designed to present the customer with the finest solutions
and best possible results. Thanks to the vast knowledge accumulated at Solano, as well
as close collaboration with veterinarians from Israel and around the world, we are able
to provide solutions for a wide range of needs raised by both end-customers and
veterinarians.
Our company takes great care to ensure that only the finest and safest substances are
used in the manufacturing process, so as to guarantee that your family, the
environment and your pet will all benefit from our products.
Solano, its staff and its products are always here for you - and for your pet.
Amnon Vardi Solano
Cat/Dog
The New Generation
of Tick Collars
Effective
Tick Collars for Dogs
•
•
•
•
A very effective ticks collar
Kills and repels ticks for a period of 6 months
Control release mechanism –quick and uniform dispersion
Efficacy test comparison results
60
Soltick
Competitor A
Competitor B
Competitor C
Ticks
50
40
30
20
10
0
Day 1
After 48 hs.
1 week
I month
2 months
reinfectation
4 months
6 months
Tick Collars for Dogs
Compare
Perfumed
Other Tick Collars
Neutralized bad odors & give your dog & his
environment pleasant flowers blossom for long period
Chemical Odors
Natural Aromatic Oils
Tick Collars for Dogs
Soltick Collar Design
The New Concept in Various Colors
Compare
Other Tick Collars
The Traditional Collar
Tick Collars for Dogs
Secure Closure
Unique closure design keep the collar on the
dogs neck all time. Safe with children
Compare
Other Tick Collars
Tick Collars for Dogs
Waterproof
New Polymer Technology
The efficiency is not reduce if in contact with
water
Compare
Other Tick Collars
Not Waterproof
Tick Collars for Dogs
Skin & Fur Care
The special oils makes the hair shine and prevents
hair loss and skin damages.
Compare
Other Tick Collars
Tick Collars for Dogs
Enviromental Friendly
No PVC
halogen & heavy metals free
Compare
Other Tick Collars
Made of Standard PVC
( halogens) and heavy metals
Tick Collars for Dogs
Supplied in 3 Sizes & in Various Colors
Sizes
The New Generation of Dog Spot
on Against Tick & Fleas
Spot on Solution
Effective
SOLTIF all in one- efficiency test comparison
60
Ticks
• A very efficient spot
on treatment
against ticks, fleas,
flies and mosquitoes
for dogs.
Soltif
Competitor C
30
20
10
0
60
After12 hs.
Soltif
48 hs.
10 days
reinfectation
Competitor A
11 days
Competitor B
15 days
30 days
Competitor C
50
Fleas
Based on a new
formulation of 3rd
generation
insecticides.
Competitor B
40
Day 1
•
Competitor A
50
40
30
20
10
0
Day 1
After12 hs.
48 hs.
10 days
reinfectation
11 days
15 days
30 days
Spot on Solution
Compare
speed of action
Others
Faster action – Kills all parasites in 8 hours and
works efficiently for 30 days
Over 24 hours
Spot on Solution
A new & patented formulation
Soltif is based on a combination of the most effective
insecticides ( Dinotefuran and Flumethrin). This innovative
formulation kills all parasites in all stages of life
Effective
Others
The traditional products are in the
market for many years (15-20) and
the parasites has developed high
resistance to it.
Spot on Solution
Effective
More Green chemicals
Others
Helps to protect the environment
Poisonous to fish and bees.
Spot on Solution
Effective
Puppies- allowed
Standard
Puppies- allowed and safe from age of 2 months
Not allowed
for puppies less then 4
months in most products.
Spot on Solution
Effective
More Safe
• More safe chemicals with high LD 50.
• Safe tube mechanism. protect leakage.
• Safe for use in a house with children.
• Safe for use in a house with cats.
• Does not contain alcohol
Spot on Solution
Effective
Wide Protection
• Gives wide protection against all ectoparasites.
• Less chemicals and more efficiency.
Spot on Solution
Supplied in 4 Size
The New Generation of Dog
& Cat Spot on Against Fleas
Spot on Solution
Effective
Solpreme Dog & Cat – efficiency comparision
60
Fleas
• A very efficient
spot on treatment
against fleas, flies
and mosquitoes
for cats and dogs.
Solpreme Dog
50
Competitor A
Competitor B
Competitor C
40
30
20
10
0
Day 1
After12 hs.
48 hs.
10 days
reinfectation
11 days
15 days
30 days
60
Competitor A
Competitor B
Competitor C
40
Fleas
• Based on a new
formulation of 3rd
generation
insecticides.
Solpreme Cat
50
30
20
10
0
Day 1
After12 hs.
48 hs.
10 days
reinfectation
11 days
15 days
30 days
Spot on Solution
Compare
speed of action
Others
Faster action-Kills fleas in 8 hours and works
efficiently for 30 days in all its cycles of life.
Over 24 hours
Spot on Solution
Effective
More Green chemicals
Others
Helps to protect the environment
Poisonous to fish and bees.
Spot on Solution
Effective
Puppies- allowed
Standard
Puppies- allowed and safe from age of 2 months
Not allowed
for puppies less then 4
months in most products.
Spot on Solution
Supplied:
Solpreme Cat - 2 Size & Solpreme Dog - 4 Size
Marketing
Israeli veterinarian market
Solano
others
Veterinary
Information
Effective
Disease Prevention
• The parasites transmit the disease
by the bite.
• Soltif prevents the bites of the fleas
and ticks
• Dinotefuran kills the fleas in the first
contact and Flumethrin kills and
repeals ticks by the hot feet effect.
Disease Prevention
Flea Allergy
Dermatitis (FAD)
•
•
Flea Allergy Dermatitis (FAD) is the most
common skin affliction in dogs and cats.
This dermal allergy is caused by the
animal’s allergic reaction to the flea’s
saliva.
Each time a flea feeds on an animal’s
blood, it injects its saliva under the skin.
Clinical symptoms of FADinclude itching,
redness of the skin to the point of
lesions, intensified hair loss and even
bald spots. Sometimes the cat or dog
may injure itself through biting and
scratching, primarily at the base of the
tail, lower abdomen, head and ears.
Disease Prevention
Tapeworms
(Taenia pisiformis, and
Dipylidium caninum)
•
•
Tapeworms are caused by the pet
eating/swallowing fleas carrying the
tapeworm eggs. this is the only way
to get tapeworms, by eating infected
fleas.
We kill these worms with
Praziquantel, but if the fleas on the
pet are not killed, the pet will have
tapeworms again in about another
month.
Disease Prevention
Ehrlichiosis
Ehrlichia is a type of bacteria that infect dogs and other species worldwide and is commonly
transmitted by ticks.
Ehrlichia infect white blood cells. There are many species of Ehrlichia, but there are only a few
species that affect dogs. Most Ehrlichia infections are acquired through tick bites.
Signs and Symptoms of Ehrlichiosis
The acute phase occurs within the first few weeks of being infected and is rarely fatal. Recovery can
occur, or the dog can enter a "subclinical phase" which can last for years, where there are no
symptoms. Some dogs, but not all, eventually progress to the chronic phase, where very severe
illness can develop. However, in practice is difficult to distinguish these phases.
Treatment of Ehrlichiosis
Ehrlichiosis responds well to treatment with the anitbiotic doxycycline. Reinfection is possible as
immunity to Ehrlichia bacteria is not long lasting.
Prevention of Ehrlichiosis
Preventing exposure to the ticks that carry Ehrlichia is the best means of preventing ehrlichiosis.
Products that prevent ticks such as monthly parasite preventatives or tick collars can be used.
Flumethrin
Veterinary Information
Flumethrin
Chemical
Structure:
Group:
Pyrethroid
Mode of action: Stops transition of sodium (Na) in the neuronal membrane.
Paralyzes and kills external parasites such as flies, ticks, mites, lice,
fleas and mosquitoes very quickly (knock out action)
Kills by contact.
Flumethrin
Veterinary Information
Pharmacokinetics of flumethrin:
Topically administered flumethrin remains mostly on the hair-coat of the
treated animals and is very poorly absorbed through the skin. In
contrast with natural pyrethrins and older synthetic pyrethroids,
flumethrin is quite resistant to UV-light.
If treated animals ingest flumethrin through licking or grooming a large
amount of it is excreted unchanged through the feces. The absorbed
flumethrin is quickly metabolized in the liver to inactive metabolites that
are excreted through urine.
LD50:
2000 mg/kg
Efficacy: No resistance develops-first product with flumethrin in "spot on“
system.
It is one of the best active ingredients against both single-host ticks
(e.g. Boophilus spp) and multi-host ticks (e.g. Amblyomma,
Rhipicephalus, Ixodes, Dermacentor, etc,). It is also excellent against
several scab and mange mites (e.g. Psoroptes spp., Sarcoptesspp,
etc.)
Dinotefuran
Veterinary Information
Dinotefuran
Chemical Structure:
Group:
3rd generation insecticide of the neonicotinoid class.
Highly effective against fleas and flies.
Mode of action: blocks the receptors of transmitters in the neurons of the fleas.
Rapidly paralyzes and kills the insect.
Kills by contact.
Speed of action: rapidly affective (6 hours).
Dinotefuran
Veterinary Information
LD50:
2000 mg/kg
Efficacy: The newest generation of Ectoparasites for pets.
Since Dinotefuran used in the U.S. only for the last 7 years and just
now starts in Europe the ectoparasites has not developed resistant
to it.
Pharmacokinetics of Dinotefuran:
Dinotefuran remains mostly on the dogs and cat's surface and is not
absorbed.
Even in cases of licking and grooming in laboratory animals ingested
Dinotefuran was almost completely absorbed (>90%) quickly
distributed throughout the whole body and also rapidly eliminated,
mostly through urine in the form of unchanged Dinotefuran.
Dinotefuran
Veterinary Information
Amitraz
Veterinary Information
Amitraz
Chemical Structure:
Repels and kills ticks.
Group:
Amidine
Mode of action: Neutralize the receptors of octopamine (neurological
transmitters) of the ticks.Parasites become hyperexcited, paralyzed
and eventually die.
Kills bycontact. Ticks diebefore biting.
Speed of action: Dermal absorption of Amitraz is low, less than 10% in dogs.
Amitraz
Veterinary Information
LD50:
100 mg/kg
Efficacy: Amitraz is a veteran ectoparasiticide, but still an excellent tickicide.
It is effective against ticks that are already resistant to synthetic
pyrethroids and/or organophosphates.
PipronylButoxide
(synergist)
Veterinary Information
PipronylButoxide (synergist)
Chemical Structure:
Not an insecetcide.
Mode of action: neutralize enzymes who contribute to synergist the
pesticide (dinotefuran).
PBO acts as a synergist, meaning it makes the killing ingredients
in insecticides more effective.
LD50:
6500 mg/kg.
Efficacy test
Efficacy Test
Test conditions
• During the test, all the animals were fed with
the same commercial food.
• Veterinary control -every 2 days (including
weight and visual control).
• Blood samples in the beginning and in the end
of the test.
Tick Collars for Dogs
Efficacy Test
Tick collar for dogs:
Ticks number
efficacy test comparison with other collars
Efficacy Test
Tick Collars for Dogs
Tick collar for dogs
water resistance test comparison vs. other collars
• Soltick and all other collars were immersed in water for 2 days prior to the test.
• All dogs were washed every two days.
60
Soltick
Competitor A
Competitor B
Competitor C
Ticks number
50
40
30
20
10
0
Day 1
After 48 hs.
1 week
I month
2 months
reinfectation
4 months
6 months
Spot on Solution
Efficacy Test
Comparison of
Soltif vs. other spot on
Tick number
60
Soltif
Competitor A
Competitor B
Competitor C
Ticks number
50
40
30
20
10
0
Day 1
After12 hs.
48 hs.
10 days
reinfectation
11 days
15 days
30 days
Spot on Solution
Efficacy Test
Comparison of
Soltif vs. other “spot on”
60
Soltif
Competitor A
Competitor B
Competitor C
Fleas number
50
40
30
20
10
0
Day 1
After12 hs.
48 hs.
10 days
reinfectation
11 days
15 days
30 days
Spot on Solution
Efficacy Test
Comparison of
Solpreme vs. other cat “spot on”
60
Solpreme cat
Competitor A
Competitor B
Competitor C
Fleas number
50
40
30
20
10
0
Day 1
After12 hs.
48 hs.
10 days
reinfectation
11 days
15 days
30 days
Spot on Solution
Efficacy Test
Comparison of
Solpreme dog vs. other “spot on”
60
Solpreme Dog
Competitor A
Competitor B
Competitor C
Fleas number
50
40
30
20
10
0
Day 1
After12 hs.
48 hs.
10 days reinfectation
11 days
15 days
30 days
Some work hard
& some use Solano