1 Aspartame as a cofactor in the Autism Epidemic? The US is in the

The chemicals we ingest
The chemicals we ingest may may affect more than
our own health. They
affect more than our own health.affect the health and
vitality of future
They affect the health and vitalitygenerations. The
danger is that many of
these chemicals may
of future generations. The
not harm us but will do
silent violence to our
danger is that many of these
children.
chemicals may not harm us but
Senator Abraham S. Ribicoff
(l971)
will do silent violence to our
children.
Aspartame as a cofactor in the
Autism Epidemic?
Kenneth Stoller, MD, FAAP
President, International Hyperbaric Medical Assoc.
Medical Director, Hyperbaric Medical Center, New Mexico
Medical Director, Hyperbaric Oxygen Clinic Sacramento
Senator Abraham S. Ribicoff (l971)
AutismOne May 27, 2006 Chicago
1965
GD Searle Chemist accidentally
discovers a substance 180
sweeter than sugar with no
calories
Aspartame
The US is in the midst of a
DEVASTATING EPIDEMIC
of neurodevelopmental disorders
Pentagon lists Aspartame as prospective
biochemical warfare weapon
1
1967
1971
University of Wisconsin
Monkey study
Seven monkeys fed
Aspartame mixed with
milk. One dies, 5 have
Grand Mal seizures
St Louis School of Medicine
Washington University
Dr. Harry Waisman, director Joseph
P Kennedy Jr memorial Lab of
Mental Retardation Research
Mice study
Aspartic acid, one of the
main constituents of
aspartame, causes hole in
the brains of infant mice
Dr. John Olney, professor of
neuropathology and psychiatry
Ann Reynolds of GD Searle confirms
Olney’s findings
In 1973, Searle applies for FDA approval and
In 1973, Searle applies for FDA approval and submits over
submits
overit100
studies
it claims
support
100 studies
claims
support
aspartame’s
safety
1973, Dr Martha Freeman of the FDA Division of
Metabolic and Endocrine Drug Products sends
Memo:
aspartame’s safety
Neither the dead monkeys nor the
mice with holes in their brains are
included in the submission.
Neither the dead monkeys nor the
mice
with holessubmitted
in their brains
are
Information
by Searle
included
in thewith
submission.
inadequate
regard to the
toxic breakdown product
diketopiperazine (DKP)
Dr John Olney,
1974
James Turner & the
group Legal Action
for Buyer’s
Education and
Labeling
file formal objection
to aspartame’s
Neither
approval
citing the dead monkeys nor
evidence
miceit could
with holes in their brains
cause brain damage,
included
particularly
in in the submission.
children
Dr John Olney, James Turner &
the group Legal Action for Buyer’s
the
Education and Labeling
are
file formal objection to
aspartame’s approval citing
evidence it could cause brain
damage, particularly in children
1974 1974
In 1973, Searle applies for FDA approval and submits over 100
studies it claims support aspartame’s safety
FDA commissioner Alexander
Schmidt grants aspartame its
first approval as a “food
additive” in dry goods despite
FDA scientists finding serious
deficiencies in the data
submitted by Searle
HEW Secretary Caspar Weinberger appointed Schmidt Commissioner of
Food and Drugs in July 1973
2
19751975
In 1973, Searle applies for FDA approval and submits over 100
studies it claims support aspartame’s safety
Concerns about the accuracy of
test data submitted to the FDA
by Searle prompt Schmidt to
appoint a special task force to
examine irregularities in 25 key
studies for aspartame.
1975
1975
In 1973, Searle applies for FDA approval and submits over 100
studies it claims support aspartame’s safety
Searle withdraws
aspartame from the
market pending
results of an FDA
inquiry. The inquiry
board doesn’t
convene for another
four years
HEW Secretary Caspar Weinberger appointed Schmidt Commissioner of
Food and Drugs in July 1973
FDA Task Force 1976
FDA Task Force 1976
500 page report of Searle’s testing procedures
New Task force formed headed by Jerome Bressler
Schmidt: “[Searle’s
studies were]
incredibly sloppy
science. What we
discovered was
reprehensible.”
1977 Grand Jury
FDA chief counsel Richard Merrill requests US
Attorney‘s office to investigate whether
indictments should be filed against Searle.
This task force would
look into the
irregularities in
Searle’s aspartame
studies uncovered by
the original task force.
While the grand jury
investigation is
underway, Searle‘s
law firm recruits
Samuel Skinner, the
US attorney in
charge of the
investigation. Skinner
takes job with Searle‘s
law firm Sidley &
Austin.
1977
3
The legal case is
passed to William
Conlon, and despite
complaints from the
Justice Department,
Conlon stalls the
grand jury until the
statute of limitations
on the aspartame
charges runs out and
the investigation is
dropped.
1977
Conlon leaves the
Justice Depart.
and joins Searle‘s
law firm, Sidley
& Austin
Bressler Report
1977
1977
Rumsfeld CEO
“The question you have to
ask yourself is: why
wasn’t greater care
taken? Why didn’t Searle,
with their scientists,
closely evaluate this,
knowing full well that the
whole society, from the
youngest to the elderly,
from the sick to the
unsick…will have access
to this product.”
Former
Congressman
and Secretary of
Defense under
Ford is hired to
turn things
around for
Searle
Verrett Report
1977
FDA is pressured to
create another task force
to review the Bressler
report. The new task force
is headed by Jacqueline
Verrett.
FDA publishes a report
exonerating Searle of any
wrongdoing in its testing
procedures.
1978
Conlon leaves
the Justice
Depart. and
joins Searle‘s
law firm,
Sidley &
Austin
• Tumors were
removed from
live animals and
then put back
into the studies.
• Various rats
were reported
alive, then dead,
then alive again
1979
• Verrett will later
testify to the US
Senate (1987) that
her team was
forced into
validating data
from experiments
that were clearly a
FDA finally
holds a public
board of inquiry
(PBOI) - to
review the
objections of
Olney & Turner
“disaster”
4
John W. Olney, MD
John W. Olney, MD
Professor of Psychiatry &
Neuropathology,
Departments of Psychiatry
& Pathology, Washington
University School of
Medicine
Professor of Psychiatry &
Neuropathology,
Departments of Psychiatry
& Pathology, Washington
University School of
Medicine
“The FDA has a
special obligation to
protect children”
“There is no margin
of safety for the use
of aspartame in the
child’s diet”
Aspartame Board of Inquiry
Aspartame Board of Inquiry
1980 The FDA’s PBOI votes
unanimously against
aspartame’s approval
John W. Olney, MD
Professor of Psychiatry &
Neuropathology,
Departments of Psychiatry
& Pathology, Washington
University School of
Medicine
Neither the dead monkeys nor the
mice with holes in their brains are
included in the submission.
“Aspartame will
contribute to the
incidence and severity
of mental retardation
in fetuses and
children”
“it has not been presented with proof of
reasonable certainty that aspartame is safe
for use as a food additive”
Aspartame Board of Inquiry
1981
1981
Rumsfeld vows to
use political rather than
scientific means to get the
FDA to approve aspartame
Arthur Hull Hayes, Jr
pharmacologist and
Defense Department
contract researcher
Becomes FDA
Commissioner
Brags he will “call
in his markers”
Searle sales meeting?
5
1981
Arthur Hull Hayes, Jr
He ignores the
recommendations of the
FDA’s commission to review
the PBOI’s decision and
approves aspartame to be
used in dry goods, tabletop
sweetener, for breakfast
cereals, chewing gum, instant
coffee, tea, and in dairyproducts
1983
z Secret
human studies were done in Mexico
City by Searle, an unpublished study that
reportedly showed that aspartame destroyed
the brain and central nervous system, and
hardened the synovial fluids. Some people
got brain tumors and others had seizures. A
pregnant woman lost her baby.
1981
Rumsfeld CEO
Gets $12 million
Bonus
1983 – First
Secret human studies were
done in Mexico
carbonated
beverages
1983
First
carbonated
beverages
City by
Searle,
in l983 unpublished
studies
containing
aspartame
go
on
sale
that showed that
aspartame destroyed
the
containing
aspartame
brain and centralin
nervous
system,
and
USA
hardened the synovial fluids. Some people
gogoton
saleandin
USA
brain tumors
othersthe
had seizures.
A
z
pregnant woman lost her baby.
6
1983
1978
Conlon leaves the
Justice Depart.
and joins Searle‘s
law firm, Sidley
& Austin
Arthur Hull Hayes, Jr
Resigns as FDA
commissioner for using the
General foods corporate jet
multiple times (GF was and
is a major purchaser of
aspartame)
Hayes takes
$1000/day job
at BurstonMarsteller, the
PR firm for
both Searle
and Monsanto
1984
FDA denies Turner &
Monte’s requests for a
hearing. The FDA states it
reviewed all data and
concluded that “the studies
demonstrated the safety of
these (aspartame’s)
components.”
But then asks the CDC to investigate a
number of cases of adverse reactions to
aspartame coming into the FDA
Woodrow Monte is the Director of ASU’s Food Science & Nutrition Lab
1984 – CDC’s review of public
complaints “Evaluation of
Consumer Complaints Related to
Aspartame Use”
Use”
Notes re-challenge
tests show that
sensitive individuals
consistently produce
the same adverse
symptoms each time
they ingested
aspartame
REPORTED SYMPTOMS INCLUDE
Aggressive behavior
Disorientation
Hyperactivity
Memory loss
Seizures
Mood swings
Cardiac arrest
Liver impairment
Suicidal tendencies
Death
7
CDC coverup of the report
A summary was added
to this investigation
that contradicted the
report saying that the
findings were
"mild". By virtue of
this short oneparagraph summary (to
a 146 page report) the
term "mild death" is
now a defacto part of
CDC jargon
1984 – study at ASU in
Journal of Applied
Nutrition determines that
soft drinks stored at
elevated temperatures
promote deterioration of
aspartame into methanol
(and DKP)
1985
Monsanto, the producer of bovine
growth hormone, genetically
engineered soy, and the pesticide
Roundup, purchases Searle for
$2.7 billion
National Soft Drink Association objects to
aspartame’s approval for carbonated beverages
1985
Section 402 of the FDC Act 21 provides a food is adulterated if it
contains, in whole or in part "...a decomposed substance or if it is
otherwise unfit for food.”
"Searle has not demonstrated to a reasonable
certainty that aspartame and its degradation products
are safe for use in soft drinks. ... Aspartame is
inherently markedly and uniquely unstable in aqueous
media. In a liquid, such as a soft drink, aspartame will
degrade as a function of temperature and pH."
Congressional Record of May 7, l985, Page S 5509, Senate
1985
Metzenbaum
introduced a Bill
entitled, “The
Aspartame Safety
Act of 1985.” He
considered this the
absolute minimum
that Congress
needed to do in
Howard M. Metzenbaum (D-Ohio) served
for 19 years in the U.S. Senate, where he order to protect the
was a champion for working families and
health and safety of
an active member of the Senate Labor and
Judiciary Committees
the public.
8
1986
US Supreme Court, lead by
Justice Clarence Thomas, a
former Monsanto attorney,
refuses to consider arguments
from consumer groups that the
FDA did not follow proper
procedures in approving
aspartame.
US Senate Hearing 1987
“It was pretty obvious that
somewhere along the line, the bureau
officials were working up to a
whitewash.” Jacqueline Verrett
Verrett reveals that while compiling its 1977
report, her team was instructed not to
comment or be concerned with the validity
of the studies. She states the questions of
birth defects have not been answered and
notes that increasing the temperature of
aspartame increase DKP
The Guardian (UK)
1990 – The Guardian publishes a
major investigation of aspartame
and delivers to UK government
officials “a dossier of evidence”
(excerpts of the Bressler Report)
and demands a review. Instead the
The Guardian is taken to court by
Monsanto and forced to apologize
for printing the story.
US Senate Hearing 1987
held to address the issue of aspartame safety and labeling
This is where it was
revealed that
aspartame was
once on a Pentagon
list of prospective
biochemicalwarfare weapons
1989
Dr. HJ Roberts,
director of the Palm
Beach Institute of
Medical Research,
claims that several
recent aircraft
accidents involving
confusion and
aberrant pilot
behavior were
caused by aspartame
1989
1992
What corporations
have known for some
time is discussed,
albeit it briefly, in the
press- the “Science
Mob” is for sale and
most of them will
keep secrets if it
means keeping their
jobs.
9
HHS compiles a report
listing all CDC and
FDA complaints
against aspartame
which now accounts for
75% of all the
complaints in the US
adverse-reaction
monitoring system.
1994
Betty Martini uses the Freedom
of Information Act to force
the FDA to release an official
list of adverse effects
associated with aspartame.
Complaints now exceed
10,000 – the FDA states < 1%
of those who have problems
report it to the FDA which
means over a 1 million people
have been experiencing
adverse effects from
aspartame.
Betty Martini
1995
1996
The FDA promptly
announces it will not
continue to collect
adverse reaction
reports or monitor
research on aspartame.
Dr. David Kessler, FDA
Commissioner, granted
aspartame blanket approval
to be used the same as
sugar... in everything! He did
so without public
notification, and shortly after
being requested by retired
Senator Metzenbaum to
initiate additional safety
testing.
Now Dean of Yale Med School
1995
Olney publishes peerreviewed research
showing that brain
tumor rates have risen
in line with aspartame
consumption.
1996
Independent scientists from the University
of Barcelona publish landmark study
showing aspartame is transformed into
formaldehyde in the living animals and
transported to all organs throughout the
animal.
1998
10
2000
1999
An investigation by
The Independent on
Sunday reveals that
aspartame is made
using a genetic
engineering process.
1999
Monsanto, under pressure – not least from the
worldwide resistance to genetically engineered
food and ongoing lawsuits – sells Nutrasweet
to JW Childs Associates, a leading private
equity firm specializing in leveraged buyouts
and recapitalizations.
2004
The documentary that examines how
inadequate food safety requirements
gave birth to toxins being accepted into
our food supply.
QuickTime™ and a
Sorenson Video 3 decompressor
are needed to see this picture.
Includes interviews with Dr. Russell
Blaylock, Dr. Joseph Mercola, Jim
Turner, ESQ, Dr. Michael Ruff, Dr.
Candace Pert, Noam Chomsky, Sheldon
Rampart, Jeffrey Smith, Jack Samuels,
Dr. Janet Starr Hull, Mary Nash
Stoddard, Spice Williams Crosby, Bob
Wall, Larry Hagman, David Getoff,
Howard Glasser, Sally Fallon, Robert
Scott Bell, Arthur Evangelista, Betty
Martini, and many more.
2005
2006
The Ramizzini Institute in
Bologna, Italy - a non-profit,
private institution set up to
research the causes of cancer.
The 3-year Ramizzini study condemned aspartame as a
"multipotential carcinogen." In the USA Merisant's sales
dropped 22% and Holland Sweetener, Europe's largest
aspartame producer said they were out of the aspartame
business.
Dr. Morando Soffritti who led tests at Ramizzini
A dose-related statistically significant
increase of lymphomas and leukemias
in female rats. This statistically
significant increase was also observed
at a dose level of 20 mg/Kg of body
weight, a dose inferior to the accepted
daily intake permitted by current
regulations (50-40 mg/Kg of body
weight).
So something had to be done and fast. Denying any link to
aspartame manufacturers, the EFSA group lead by Dr
Herman Koéter dismissed the Ramizzini cancer study and
pronounced aspartame safe for all to consume.
But “all” have outside careers with financial ties to
aspartame producers.
11
z
z
New Mexico Senator Ortiz y Pino,
February 10, sent a letter signed with 10
other state legislatures asking that
Governor Richardson declare a state of
Public Health Emergency on or before
February 13, 2006 regarding the effects of
aspartame/methanol/formaldehyde
poisoning.
Ajinomoto hired the Governor’s best friend, Walter “Butch” Maki and his
affiliates, former Governor Jerry Apodaca, and former Governor David Cargo,
Former House Majority Leader Richard MINZNER to make sure nothing was
done to interfere with the sale of aspartame products.
The New Mexico Food Act (25-2-1
to 25-2-19 and 25-2-20 NMSA
l978) on adulterated and poisonous
foods is a strong, clear law with its
criminal prosecution provisions for
violators.
The Statute provides that: A food
shall be deemed to be adulterated,
(1) if it contains any poisonous or
deleterious substance which may
render it injurious; (2) if it contains
any added poisonous or added
deleterious substance which is
unsafe, and (3) if it consists in
whole or in part of ... decomposed
substance, or if it is otherwise unfit.
Just keep
postponing the
hearing
Ajinomoto Corp of
Japan (the world's
largest aspartame
and MSG
manufacturer)
Senator Ortiz y Pino's SB 654, the Bill to
Ban the neurotoxic carcinogenic poison
Aspartame from human consumption in
New Mexico SB 654 was tabled in the
Senate Public Affairs Committee.
The committee voted 5-2 after
being heavily lobbied by COCA
COLA, PEPSI COLA, "CALORIE
CONTROL COUNCIL," AND
AJINOMOTO.
NIH, NCI halt spin on bogus
aspartame study
z
The Calorie Control Council (CCC) has been boasting
about a 1996 AARP and NIH "Diet & Health Study" they
say proves aspartame doesn't cause cancer.
z
On April 18, 2006, Don Harkins, editor of the Idaho
Observer, called the press secretary for NIH and NCI,
Jennifer Thompson, to see what they think of CCC's use of
AARP's "study" to exonerate aspartame. Ms. Thompson said
the conclusion is "premature" and is "an interesting piece of
evidence" but not scientific proof. Harkins reports:
"Thompson didn't disagree when I indicated it was
irresponsible for the CCC, which has a special interest
about claims aspartame is safe for human consumption, to
have used the abstract from an UNPUBLISHED study to
claim aspartame safety. Further, AARP isn't qualified as a
scientific research entity to make any claims one way or
another. That means CCC, as a special conflicted interest,
has no backing for these claims. Likewise, the American
Dietetic Assn. And the American Beverage Assn. are
conflicted interests unsupported in their claims."
z
12
Corruption, Deception and Depravity
and Depravity
Each of us are obligated
to vote with our feet, our
wallets and our voices to
claim the rights and
powers that were taken
from us while we slept to end the unholy alliance
between corporation &
state that demonstrates
over and over that it will
poison all of us to make a
buck.
Deception
ManyCorruption,
within our
government are loyal
public servants
dedicated to their
mission of protecting the
United States and
serving its people no
matter in what agency
they serve. Those in
lower ranking positions
don't know what
happens in the higher
levels of authority, much
less that some of their
colleagues are rogue
agents carrying out the
biding of their nefarious
handlers.
The chemicals we ingest
affect more than
The chemicals we ingest may may
our own health. They
the health and
affect more than our own health.affect
vitality of future
The
They affect the health and vitalitygenerations.
danger is that many of
these chemicals may
of future generations. The
not harm us but will do
silent violence to our
danger is that many of these
children.
chemicals may not harm us but Senator Abraham S. Ribicoff
(l971)
will do silent violence to our
children.
Senator Abraham S. Ribicoff (l971)
13