Monday, August 3, 2015
Transcription
Monday, August 3, 2015
Eurocarb18 Program Overview PROGRAM OVERVIEW Sunday, August 2, 2015 10:00-14:00 12:30-19:00 Moscow City Bus Sightseeing Tour Registration 16:00-18:30 OPENING SESSION PLENARY SESSION 1 19:00-22:30 Opening Ceremony Emil Fischer Award Lecture (J.-P. Latgé, France) Carbohydrate Research Award Lecture (D. Vocadlo, Canada) Welcome Party Monday, August 3, 2015 8:30-14:30 9:00-10:30 10:30-11:30 11:30-12:50 12:50-14:30 14:30-16:00 16:00-17:00 17:00-18:25 19:00-21:30 9:00-17:00 Registration PLENARY SESSION 2 Coffee Break POSTER SESSION 1A PARALLEL SESSIONS 01-03 Lunch PARALLEL SESSIONS 04-06 Coffee Break POSTER SESSION 1B PARALLEL SESSIONS 07-09 Cocktail Party Concert Serigiev Posad Tour for Accompanying Persons 1 Eurocarb18 Program Overview Tuesday, August 4, 2015 9:00-10:30 10:30-11:30 11:30-12:55 12:55-14:30 14:30-16:00 16:00-17:00 17:00-18:25 19:00-22:30 PLENARY SESSION 3 Coffee Break POSTER SESSION 2A PARALLE L SESSIONS 10-12 Lunch PARALLEL SESSIONS 13-15 Coffee Break POSTER SESSION 2B PARALLEL SESSIONS 16-18 Symposium Dinner Wednesday, August 5, 2015 9:00-10:45 10:45-11:15 11:15-12:35 13:00-20:00 PARALLEL SESSIONS 19-21 Coffee Break PARALLEL SESSIONS 22-24 Optional Sightseeing Tours Thursday, August 6, 2015 9:00-10:30 10:30-11:00 11:00-12:40 12:40-14:00 14:00-15:45 15:45-16:15 16:15 PLENARY SESSION 4 Coffee Break PARALLEL SESSIONS 25-27 Lunch PARALLEL SESSIONS 28-30 Coffee Break CLOSING SESSION Presentation of Eurocarb19 Presentation of ICS 2016 Closing Remarks 2 SCIENTIFIC PROGRAM 3 Eurocarb18 August 2, 2015 Scientific Program SUNDAY, AUGUST 2, 2015 12:30-19:00 Registration Foyer 16:00-18:30 OPENING SESSION PLENARY SESSION 1 Tchaikovsky Hall 16:0016:30 Opening Ceremony Welcome addresses: Yuriy A. Knirel Symposium Chair Alexander G. Gabibov President of the Russian Biochemistry and Molecular Biology Society Sergei O. Bachurin Head of the Moscow Branch of the Mendeleev Russian Chemical Society Timor Baasov President of the European Carbohydrate Organisation 16:3017:30 Plenary Lecture PL01 Emil Fischer Award Lecture Chair: Timor Baasov, Israel POLYSACCHARIDES OF THE CELL WALL OF THE HUMAN FUNGAL PATHOGEN Aspergillus fumigatus AND THEIR ROLE IN FUNGAL VIRULENCE Jean-Paul Latgé Unité des Aspergillus, Institut Pasteur, Paris, France 17:3018:30 Plenary Lecture PL02 Carbohydrate Research Award Lecture Chair: Rob Field, UK CHEMICAL BIOLOGY OF O-GlcNAc: ENZYME FUNCTION TO ROLES IN CELLULAR PHYSIOLOGY AND DISEASE David Vocadlo Department of Chemistry and Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, Canada 19:00-22:30 Welcome Party Extra Lounge 4 Eurocarb18 August 3, 2015 Scientific Program MONDAY, AUGUST 3, 2015 8:30-14:30 Registration 9:00-10:30 PLENARY SESSION 2 9:009:45 Plenary Lecture PL03 Foyer Tchaikovsky Hall Chair: Nikolay E. Nifantiev, Russia C-MANNOSYLATION OF TRYPTOPHAN RESIDUES IN PROTEINS Hans Bakker Department of Cellular Chemistry, OE4330, Hannover Medical School, Hannover, Germany 9:4510:30 Plenary Lecture PL04 Chair: Johannes F. G. Vliegenthart, The Netherlands FROM CARBOHYDRATES TO GLYCOMIMETICS IS THERE A GENERAL RECIPE? Beat Ernst Institute of Molecular Pharmacy, Pharmacenter, University of Basel, Basel, Switzerland 10:30-11:30 Coffee-break / POSTER SESSION 1A Place de Paris 11:30-12:50 PARALLEL SESSIONS 01-03 SESSION 01. Synthesis of carbohydrates: new approaches I Tchaikovsky Hall Chair: Thisbe Lindhorst, Germany 11:3012:00 Keynote Lecture KL01 FROM STEREOCONTROLLED GLYCOSYLATION TO EXPEDITIOUS OLIGOSACCHARIDE SYNTHESIS Alexei V. Demchenko Department of Chemistry & Biochemistry, University of Missouri, St. Louis, Missouri, USA 12:0012:15 PALLADIUM-CATALYZED DECARBOXYLATIVE COUPLING FOR EFFICIENT ALLYLATION OF ACID/BASE SENSITIVE OLIGOSACCHARIDES Wenqing Liu, A. Alix, D. Bonnaffé Groupe Glycosaminoglycanes et diversité Moléculaire, Equipe Méthodologie, Synthèse et Molécules Thérapeutiques, ICMMO, UMR 8182 (CNRS-UPS), LabEx LERMIT, Université Paris-Sud, Orsay, France 5 Eurocarb18 August 3, 2015 Scientific Program 12:1512:30 PREPARATION AND OLIGOMERIZATION OF BIOSOURCED MALTOTRIOSIDE BUILDING BLOCKS: TOWARDS HEPARAN SULFATE MIMETICS? Yunyu Lu, Z. Hu, C. Le Narvor, D. Bonnaffé Groupe Glycosaminoglycanes et diversité Moléculaire, Equipe Méthodologie, Synthèse et Molécules Thérapeutiques, ICMMO, UMR 8182 (CNRS-UPS), LabEx LERMIT, Université Paris-Sud, Orsay, France 12:3012:45 UNDERSTANDING THE REGIOSELECTIVITY OF THE REACTION OF UNPROTECTED NUCLEOSIDE WITH P-NITROPHENYL PHOSPHATE: EFFICIENT ONE-POT SYNTHESIS OF 2’, 3’-CYCLICPHOSPHATE-5’-PHOSPHATE RIBOSIDES Lu Tang, M. Macé, D. Bonnaffé, C. Le Narvor Groupe Glycosaminoglycanes et Diversité Moléculaire, Equipe Méthodologie, Synthèse et Molécules Thérapeutiques, ICMMO, UMR 8182 (CNRS-UPS), LabEx LERMIT, Université Paris-Sud, Orsay, France SESSION 02. Carbohydrates for medicine I Shostakovich Hall Chair: Amelia Rauter, Portugal 11:3012:00 Keynote Lecture KL02 TARGETING DENDRITIC CELL RECEPTORS BY GLYCOCONJUGATE LIGANDS K. C. McCullough,a Panagiota Milona,a N. Bovinb a Institute of Virology and Immunoprophylaxis, Mittelhäusern, Switzerland b Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia 12:0012:20 ANION SELECTIVE ARTIFICIAL CHANNELS BASED ON SMART GLYCOMOTIFS T. Saha,a A. Roy,a M. L. Gening,b D. V. Titov,b A. G. Gerbst,b Y. E. Tsvetkov,b N. E. Nifantiev,b S. Dasari,a D. Tewari,c A. Prathap,d K. M. Sureshan,d A. K. Bera,c A. Mukherjee,a Pinaki Talukdara a Indian Institute of Science Education and Research Pune, Pune, India b Laboratory of Glycoconjugate Chemistry, N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia c Department of Biotechnology, Indian Institute of Technology Madras, Chennai, India d School of Chemistry, Indian Institute of Science Education and Research Thiruvananthapuram, Thiruvananthapuram, India 12:2012:35 POLYSACCHARIDE-CONTAINING HYDROGELS FOR THE PREVENTION OF MUCOSAL VIRAL INFECTIONS G. Ponchel,a J.-M. Mallet,b Kawthar Bouchemala a Institut Galien Paris Sud, UMR CNRS 8612, School of Pharmacy, University Paris Sud, Châtenay-Malabry, France b École Normale Supérieure-PSL Research University, Département de Chimie, Paris, France 6 Eurocarb18 12:3512:50 August 3, 2015 Scientific Program FimH ANTAGONISTS AS A NOVEL APPROACH FOR THE PREVENTION AND TREATMENT OF URINARY TRACT INFECTIONS Deniz Eris,a R. C. Preston,a R. P. Jakob,b M. Scharenberg,a F. Hulliger,a A. Mazur,b T. Maier,b B. Ernsta a Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland b Department Biocenter, University of Basel, Basel, Switzerland SESSION 03. Biosynthesis of carbohydrates I Versailles Hall Chair: Tatyana Gorshkova, Russia 11:3012:00 Keynote Lecture KL03 GLYCOSYLATION IN TRYPANOSOMES Michael Ferguson College of Life Sciences, University of Dundee, Dundee, UK 12:0012:20 ROLE OF THE CONSERVED OLIGOMERIC GOLGI COMPLEX AND COG-INTERACTING VESICLE TRAFFIKING MACHINERY IN GLYCOSYLATION Vladimir V. Lupashin, J. Bailey, L. Climer, I. D. Pokrovskaya, R. A. Willett Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA 12:2012:35 GLYCOSIDIC-BOND BIOSYNTHESIS BY “FRONT-SIDE NUCLEOPHILIC ATTACK”. A SHORTCUT FOR EFFECTIVE SUGAR TRANSFER ANALYZED BY QM/MM CALCULATIONS Laura Masgrau,a F. Mendoza,a H. Gómez,b J. M. Llucha a Universitat Autònoma de Barcelona, Bellaterra, Spain b IRB, Barcelona, Spain 12:3512:50 DETERMINATION OF BACTERIAL GLYCOSAMINOGLICAN-LIKE CAPSULAR POLYSACCHARIDE NUCLEOTIDE SUGAR PRECURSORS Odile F. Restaino, I. di Lauro, E. Carlino, C. Schiraldi, M. De Rosa Second University of Naples, Naples, Italy 12:50-14:30 Lunch Place de Paris 14:30-16:00 PARALLEL SESSIONS 04-06 SESSION 04. Synthesis of carbohydrates: new approaches II Tchaikovsky Hall Chair: Richard Schmidt, Germany 14:3015:00 Keynote Lecture KL04 SYNTHETIC APPROACHES TO STABILIZE AND TO LOCK GLYCOSIDIC BONDS Daniel B. Werz Technische Universität Braunschweig, Institute of Organic Chemistry, D38106 Braunschweig, Germany 7 Eurocarb18 August 3, 2015 Scientific Program 15:0015:20 NEW PROTECTING GROUP MANIPULATIONS IN OLIGOSACCHARIDE SYNTHESIS Anne Geert Volbeda, H. S. Overkleeft, G. A. van der Marel, J. D. C. Codée Leiden Institute of Chemistry, Universiteit Leiden, Leiden, The Netherlands 15:2015:40 ON THE REACTIVITY AND SELECTIVITY OF 2-AZIDO-2-DEOXYFUCOSYL DONORS AND THEIR APPLICATION IN OLIGOSACCHARIDE SYNTHESIS Bas Hagen, S. Ali, H. S. Overkleeft, G. A. van der Marel, J. D. C. Codée Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands 15:4015:55 ORGANOCATALYTIC GLYCOSYLATIONS Eoghan M. McGarrigle, G. Bradshaw, A. C. Colgan, N. P. Allen, M. Boland Centre for Synthesis & Chemical Biology, UCD School of Chemistry & Chemical Biology, University College Dublin, Belfield, Dublin, Ireland SESSION 05. Carbohydrate structure analysis: new approaches I Shostakovich Hall Chair: Serge Pérez, France 14:3015:00 Keynote Lecture KL05 A ROLE FOR UNDERLYING GLYCAN STRUCTURE IN INFLUENZA BINDING: EXTENDING THE SPECIES SPECIFICITY PARADIGM O. C. Grant,a J. A. Hadden,a J. Ye,a H. M. K. Smith,b W. Peng,c R. De Vries,c R. McBride,c J. C. Paulson,c Robert J. Woodsa,b a Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia, USA b School of Chemistry, National University of Ireland, Galway, Ireland c Departments of Cell and Molecular Biology, Chemical Physiology, & Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, USA 15:0015:20 THE 3D STRUCTURE OF A FUCOSYLATED CHONDROITIN SULFATE ISOLATED FROM THE BODY WALL OF THE SEA CUCUMBER Holothuria forskali AND ITS INTERACTION WITH SELECTINS Charalampos Panagos,a,b D. Thomson,b C. Moss,b C. D. Bavington,b M. Barbara,c Y. Liu,d T. Feizi,d W. Chai,d D. Uhrína a EastCHEM School of Chemistry, Joseph Black Building, The King’s Buildings, Edinburgh, UK b GlycoMar Ltd., European Centre for Marine Biotechnology, Dunstaffnage Marine Laboratory, Oban, Argyll, UK c Kings College London, Sackler Institute of Pulmonary Pharmacology, Institute of Pharmaceutical Science, London, UK d Glycosciences Laboratory, Department of Medicine, Imperial College London, UK 8 Eurocarb18 August 3, 2015 Scientific Program 15:2015:40 J-EDITED NMR SPECTROSCOPY OF OLIGOSACCHARIDE: HOW TO EXTRACT CHEMICAL SHIFTS AND SCALAR COUPLINGS FROM HIGHLY CROWDED 1H SPECTRA David Bonnaffé,a Z. Hu,a D. Pitoux,b B. Plainchont,b D. Merlet,b J. Farjon,b N. Giraudb a Equipe Méthodologie, Synthèse et Molécules Therapeutiques, LabEx LERMIT b Equipe de RMN en Milieu Orienté ICMMO, UMR 8182 (CNRS-UPS), Université Paris-Sud, Orsay Cedex, France 15:4016:00 EXPANDING THE APPLICABILITY OF ESTABLISHED PRIMARY STRUCTURAL CHARACTERISATION METHODS Charles R. Powley, B. Szostek E. I. duPont de Nemours & Co., Inc., Wilmington, Delaware, USA SESSION 06. Biosynthesis of carbohydrates II Versailles Hall Chair: Anatolii Usov, Russia 14:3015:00 Keynote Lecture KL06 LESSONS FROM PLANT LIFE ON COMPLEX CARBOHYDRATE FORMATION AND FUNCTIONALIZATION Tatyana Gorshkova Kazan Institute of Biochemistry and Biophysics, Kazan Scientific Centre, Russian Academy of Sciences, Kazan, Russia 15:0015:20 CELL WALL POLYSACCHARIDES AS A MOLECULAR BASIS FOR PLANT CELL GROWTH Liudmila V. Kozlova, M. V. Ageeva, O. V. Gorshkov, N. N. Ibragimova, N. E. Mokshina, T. A. Gorshkova Kazan Institute of Biochemistry and Biophysics, Kazan Scientific Center, Russian Academy of Sciences, Kazan, Russia 15:2015:40 DISCOVERY OF ENZYMIC ‘TOOLS’ CAPABLE OF GRAFTING AND TETHERING CELL-WALL POLYMERS IN THE MODERN RELATIVES OF THE ALGAL ANCESTORS OF LAND PLANTS Lenka Franková, S. C. Fry The Edinburgh Cell Wall Group, Institute of Molecular Plant Sciences, The University of Edinburgh, Edinburgh, UK 15:4016:00 BIOSYNTHESIS OF XYLOGLUCAN: MULTIPROTEIN COMPLEX ORGANISATION AND MECHANISMS OF CATALYSIS Olga Zabotina, A. Culbertson, Yi-Hsiang Chou, A. Smith, A. Tietze Roy J. Carver Department of Biochemistry, Biophysics & Molecular Biology, Iowa State University, Ames, Iowa, USA 16:00-17:00 Coffee-break / POSTER SESSION 1B 9 Place de Paris Eurocarb18 August 3, 2015 Scientific Program 17:00-18:25 PARALLEL SESSIONS 07-09 SESSION 07. Synthesis of carbohydrates I Tchaikovsky Hall Chair: Horst Kunz, Germany 17:0017:25 SYNTHESIS AND BINDING INTERACTIONS OF PYRUVYLATED N-ACETYLMANNOSAMINE LIGANDS TO THE S-LAYER HOMOLOGY DOMAINS OF Paenibacillus alvei G. Martinz,a R. Blackler,b A. López-Guzmán,c P. Messner,c C. Schäffer,c S. V. Evans,b Paul Kosmaa a Department of Chemistry, University of Natural Resources and Life Sciences, Vienna, Austria b Department of Biochemistry & Microbiology, University of Victoria, BC, Canada c Department of NanoBiotechnology, University of Natural Resources & Life Sciences, Vienna, Austria 17:2517:40 ONE-POT SYNTHESIS OF BISECTED N-GLYCANS Manuel Mönnich, S. Eller, C. Unverzagt Department of Bioorganic Chemistry, Gebäude NWI, University of Bayreuth, Bayreuth, Germany 17:4017:55 MODULAR SYNTHESIS OF BISECTED N-GLYCANS WITH COREFUCOSE Thomas Luber, J. Walcher, L. Berger, M. Mönnich, M. Niemietz, C. Unverzagt Department of Bioorganic Chemistry, Gebäude NWI, University of Bayreuth, Bayreuth, Germany 17:5518:10 CHEMOENZYMATIC SYNTHESIS OF IL-6 GLYCOPEPTIDES WITH TETRAANTENNARY N-GLYCANS Lukas Perkams, C. Graf, M. Schmälzlein, C. Unverzagt Department of Bioorganic Chemistry, Gebäude NWI, University of Bayreuth, Bayreuth, Germany 18:1018:25 INVESTIGATION ON THE REACTIVITIES OF BIFUNCTIONAL ORGANOSILANES FOR APPLICATIONS IN THE SYNTHESIS OF BIOMATERIALS USED IN REGENERATIVE MEDICINE Xavier Guillory,a A. Tessier,b P. Weiss,c D. Dubreuil,b S. Colliec-Jouault,a J. Lebreton,b J. Le Bideaud a IFREMER, Laboratoire EM3B Ecosystèmes Microbiens et Molécules Marines pour les Biotechnologies, Nantes, France b CEISAM, UMR 6230, équipe Symbiose, Nantes, France c LIOAD, INSERM U791, Nantes, France d Institut des Matériaux Jean Rouxel (IMN), CNRS, Nantes, France 10 Eurocarb18 August 3, 2015 SESSION 08. Carbohydrate-active enzymes I Scientific Program Shostakovich Hall Chair: Ola Blixt, Denmark 17:0017:30 Keynote Lecture KL07 NOVEL TRANSGLYCANASES AND TRANSGLYCOSIDASES ACTING ON CELL-WALL POLYSACCHARIDES FROM PLANTS AND ALGAE Stephen C. Fry, L. Franková The Edinburgh Cell Wall Group, Institute of Molecular Plant Sciences, The University of Edinburgh, Edinburgh, UK 17:3017:55 ADVANCES IN GLYCOBIOINFORMATICS Frederique Lisacek,a,b M. P. Campbell,c J. Mariethoz,a D. Alocci,a,b R. Peterson,c O. Horlacher,a,b M. R. Macias,d M. Domagalski,a I. Walsh,e D. Kolarich,f K. Aoki-Kinoshita,g P. M. Rudd,e N. G. Karlsson,d N. H. Packerc a Proteome Informatics Group, SIB Swiss Institute of Bioinformatics, Geneva, Switzerland b Faculty of Sciences, University of Geneva, Switzerland c Biomolecular Frontiers Research Centre (BFRC), Macquarie University, Sydney, Australia d Department of Biomedicine, Gothenburg University, Sweden e NIBRT, Dublin, Ireland f Max Planck Institute of Colloids and Interfaces (MPIKG), Berlin, Germany g Department of Bioinformatics, Soka University, Tokyo, Japan 17:5518:10 NEW FAMILIES OF PUTATIVE GLYCOSIDE HYDROLASES Daniil G. Naumoff Winogradsky Institute of Microbiology, Russian Academy of Sciences, Moscow, Russia 18:1018:25 ACTIVITY-BASED GLYCOSIDASES PROFILING OF GH31 α-GLUCOSIDASES Jianbing Jiang,a W. W. Kallemeijn,a Chi-Lin Kuo,a L. Wu,b G. A. van der Marel,a J. D. C. Codée,a G. J. Davies,b J. M. F. G. Aerts,a H. S. Overkleefta a Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands b Department of Chemistry, University of York, Heslington, York, UK SESSION 09. Carbohydrate structure analysis: new approaches II Versailles Hall Chair: Antonio Molinaro, Italy 17:0017:30 Keynote Lecture KL08 BUILDING, SEEING AND PLAYING WITH COMPLEX GLYCANS Serge Pérez Department Molecular Pharmacochemistry, CNRS-Univeristé de Grenoble Alpes, Grenoble, France 11 Eurocarb18 August 3, 2015 Scientific Program 17:3017:50 CARBOHYDRATE 3D STRUCTURES IN THE PROTEIN DATA BANK: 2015 UPDATE Thomas Lütteke Justus-Liebig-University, Giessen, Germany 17:5018:10 COMPREHENSIVE N-GLYCOSYLATION CHARACTERIZATION OF THERAPEUTIC ANTIBODIES BY CAPILLARY ELECTROPHORESIS AND MASS SPECTROMETRY Andras Guttman Sciex, Brea, California, USA 18:1018:25 TOWARDS UNDERSTANDING GAS-PHASE GLYCAN STRUCTURES - ION MOBILITY SEPARATION OF ISOMERIC OLIGOSACCHARIDES IS DRIVEN BY CHARGE STATE AND METAL ION ADDUCTION Weston B. Struwe,a,b K. Pagel,c C. Baldauf,c D. Harveyb a Department of Chemistry, University of Oxford, Oxford, UK b Department of Biochemistry, Oxford Glycobiology Institute, University of Oxford, Oxford, UK c Fritz Haber Institute of the Max Planck Society, Berlin, Germany 19:00-21:30 Cocktail Party Sponsored by Elsevier on the occasion of the 50th anniversary of Carbohydrate Research Concert Place de Paris 12 Eurocarb18 August 4, 2015 Scientific Program TUESDAY, AUGUST 4, 2015 9:00-10:30 PLENARY SESSION 3 9:009:45 Plenary Lecture PL05 Tchaikovsky Hall Chair: Paul Kosma, Austria CONVERGENT SYNTHESIS OF LIBRARIES OF N-GLYCOPROTEINS Carlo Unverzagt Bioorganic Chemistry, Gebäude NWI, Universität Bayreuth, Bayreuth, Germany 9:4510:30 Plenary Lecture PL06 Chair: Hermen Overkleeft, The Netherlands EXPLORING GLYCO-TOOLS FOR NANOMEDICINE Francesco Nicotra,a L. Cipolla,a B. La Ferla,a C. Airoldi,a M. Masserini,a F. Re,a B. Costa,a M. Lecchi,a S. Antimisiaris,b G. Polzonetti,c C. Bochicchioc a University of Milano-Bicocca, Milan, Italy b University of Patras, Patras, Greece c University of Roma La sapienza, Roma, Italy 10:30-11:30 Coffee-break / POSTER SESSION 2A Place de Paris 11:30-12:55 PARALLEL SESSIONS 10-12 SESSION 10. Synthesis of carbohydrates II Tchaikovsky Hall Chair: Matthieu Sollogoub, France 11:3012:00 Keynote Lecture KL09 LIPOPOLYSACCHARIDE & CO. – SYNTHETIC ENDEAVOUR INTO THE REALM OF INNATE IMMUNITY Alla Zamyatina Department of Chemistry, University of Natural Resources and Life Sciences, Vienna, Austria 12:0012:20 SYNTHESIS OF LABELLED HEPARAN SULFATE OLIGOSACCHARIDES FOR SINGLE MOLECULE INVESTIGATION OF PROTEIN BINDING Charlotte E. Dalton,a R. A. Jeanneret,a D. R. Cummings,a S. D. Quinn,b S. W. Magennis,b J. M. Gardinera a Manchester Institute of Biotechnology and School of Chemistry, The University of Manchester, Manchester, UK b School of Chemistry, The University of Glasgow, Glasgow, UK 13 Eurocarb18 August 4, 2015 Scientific Program 12:2012:35 RAPID SYNTHESIS OF LINEAR AND BRANCHED MIMETICS OF MYCOBACTERIAL LIPOARABINOMANNAN AND NEOGLYCOCONGUGATES THEREOF Nikita M. Podvalnyy,a M.V. Panova,a,b A. O. Chizhov,a E. L. Zdorovenko,a A. I. Zinin,a V. I. Torgov,a L. O. Kononova a N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia b The Higher Chemical College of the Russian Academy of Sciences, Moscow, Russia 12:3512:50 SYNTHESIS OF SOME NATURAL DISACCHARIDE NUCLEOSIDES AND THEIR ANALOGUES Mikhail S. Drenichev, I. V. Kulikova, S. N. Mikhailov Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia SESSION 11. Carbohydrates for medicine II Shostakovich Hall Chair: Francesco Nicotra, Italy 11:3012:00 Keynote Lecture KL10 SYNTHETIC CANCER VACCINES Richard H. Furneaux, a R. J. Anderson,a B. J. Compton,a C. Tang,b A. Authier-Hall,b C. M. Hayman,a R. Kowalczyk,c M. A. Brimble,d D. S. Larsen,e O. Gasser,b R. Weinkove,b I. F. Hermans,b,c G. F. Paintera,c a Ferrier Research Institute, Victoria University of Wellington, Lower Hutt, New Zealand b Malaghan Institute of Medical Research, Wellington, New Zealand c Avalia Immunotherapies Ltd, Lower Hutt, New Zealand d The University of Auckland, New Zealand e University of Otago, Dunedin, New Zealand 12:0012:20 RECENT DEVELOPMENTS ON CARBOHYDRATE TEMPLATES FOR THE GENERATION OF MOLECULES EFFICIENT AGAINST INFECTION AND NEURODEGENERATIVE DISORDERS Amelia Rauter,a V. Cachatra,a C. Dias,a R. Nunes,a J. P. Pais,a A. Almeida,a P. Serra,a A. Martins,a J. Justinob a Centro de Química e Bioquímica, Faculdade de Ciências, Universidade de Lisboa, Lisboa, Portugal b Instituto Politécnico de Santarém, Escola Superior Agrária, Santarém, Portugal 12:2012:40 CHEMICAL STUDIES OF Quillaja SAPONIN IMMUNOSTIMULANTS DERIVED FROM THE POTENT VACCINE ADJUVANT QS-21 Alberto Fernández-Tejada,a,b J. Jiménez-Barbero,b,c D. Y. Gina a Molecular Pharmacology & Chemistry, Memorial Sloan Kettering Cancer Center, New York, NY, USA b Center for Biological Research, CIB-CSIC, Madrid, Spain c CIC-bioGUNE, Derio-Bizkaia, Spain 14 Eurocarb18 12:4012:55 August 4, 2015 Scientific Program THE EFFECT OF WHEY PROTEIN GLYCOSYLATION ON IMMUNOMODULATION AND PROBIOTIC GROWTH Akram Asadi Shehni,a A. Krüger,a R. Hickey,b M. Kilcoyne,a,c L. Joshia a Glycoscience Group, National Centre for Biomedical Engineering Science, National University of Ireland Galway, Galway, Ireland b Teagasc Food Research Centre, Moorepark, Fermoy, Co. Cork, Ireland c Microbiology, School of Natural Sciences, National University of Ireland Galway, Galway, Ireland SESSION 12. Biosynthesis of carbohydrates III Versailles Hall Chair: Antoni Planas, Spain 11:3012:00 Keynote Lecture KL11 GIANT dsDNA VIRUSES TASTE FOR SUGARS Cristina De Castro Department of Agriculture, University of Napoli, Italy 12:0012:20 IDENTIFYING SPECIFIC POLYSACCHARIDES AND ENZYMES THAT INFLUENCE THE PROPERTIES OF APPLE SKIN Roswitha Schröder,a R. Prakash,a I. Hallett,a P. Sutherland,a R. Rebstock,a H. Tiffin,b J. Ng,b E. O’Donoghue,b J. Johnston,c D. Brummellb The New Zealand Institute for Plant & Food Research Limited, aAuckland, b Palmerston North, cHavelock North, New Zealand 12:2012:40 INTERVENTION IN PLANT SIGNALLING THROUGH LIGHTACTIVATION OF AN EXOGENOUS SUGAR SIGNALLINGPRECURSOR INCREASE CROP YIELD AND RESILIENCE C. A. Griffiths,b R. Sagar,a Yiqun Geng,a L. F. Primavesi,b M. K. Patel,a M. J. Paul,b B. G. Davisa a Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford, UK b Rothamsted Research, West Common, Harpenden, Hertfordshire, UK 12:4012:55 SECRETED GLYCOSYLTRANSFERASES AS VIRULENCE FACTORS OF Legionella N. Levanova,a Yury Belyi,a T. Jank,b K. Aktoriesb a Gamaleya Research Center for Epidemiology and Microbiology, Moscow, Russia b Albert-Ludwigs University of Freiburg, Germany 12:55-14:30 Lunch Place de Paris 15 Eurocarb18 August 4, 2015 Scientific Program 14:30-16:00 PARALLEL SESSIONS 13-15 SESSION 13. Synthesis of carbohydrates: new approaches III Tchaikovsky Hall Chair: Alexei Demchenko, USA 14:3015:00 Keynote Lecture KL12 THIO-SUGAR MOTIF OF CARBOHYDRATE FUNCTIONALIZED PHARMACOPHORE AS STRATEGIC APPROACH TO THE DESIGN OF CARBOHYDRATE THERAPEUTICS Zbigniew J. Witczak Department of Pharmaceutical Sciences, Nesbitt College of Pharmacy, Wilkes University, Wilkes-Barre, Pennsylvania, USA 15:0015:20 APPLICATIONS OF INTRAMOLECULAR THIYL RADICAL REACTIONS FOR THE SYNTHESIS OF THIOSUGARS Eoin M. Scanlan School of Chemistry, Trinity Biomedical Science Institute, Trinity College Dublin, Dublin, Ireland 15:2015:40 MONO- AND MULTIVALENT IMINOSUGARS PREPARED BY PHOTOINDUCED THIOL-ENE COUPLING R. Zelli, P. Dumy, Alberto Marra Institut des Biomolécules Max Mousseron, UMR 5247, Ecole Nationale Supérieure de Chimie de Montpellier, 8 Rue de l'Ecole Normale, Montpellier, France 15:4016:00 STUDY OF THE PHOTOINDUCED HYDROTHIOLATION OF O-PERACETYLATED exo-GLYCALS Laszlo Juhász,a J. József,a D. Eszenyi,b N. Debreczeni,b A. Borbás,b L. Somsáka a University of Debrecen, Department of Organic Chemistry, Debrecen, Hungary b University of Debrecen, Department of Pharmaceutical Chemistry, Debrecen, Hungary SESSION 14. Сarbohydrate-protein interactions I Shostakovich Hall Chair: Miloš Hricovíni, Slovakia 14:3015:00 Keynote Lecture KL13 O-GalNAc PEPTIDE EPITOPES: A NOVEL TYPE OF POTENTIAL TARGETS IN DISEASE Ola Blixt Department of Chemistry, University of Copenhagen, Copenhagen, Denmark 15:0015:20 HUMAN GALECTINS BIND BACTERIAL NON-Gal POLYSACCHARIDES Nicolai V. Bovin,c Y. A. Knirel,a H.-J. Gabius,b E. M. Rapoport,c N. R. Khasbiullina,c N. V. Shilovac a N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 119991 Moscow, Russia b Institute of Physiological Chemistry, Faculty of Veterinary Medicine, Ludwig Maximilians University, 80539 Munich, Germany c Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia 16 Eurocarb18 August 4, 2015 Scientific Program 15:2015:40 ENGINEERING AND STRUCTURAL CHARACTERIZATION OF A NOVEL, SPECIFIC SIALIC-ACID BINDING PROTEIN João P. Ribeiro,a,b A. Varrot,b L. K. Mahal,a A. Imbertyb a New York University, New York, United States b CERMAV-CNRS, Grenoble, France 15:4016:00 DISCOVERY OF LIGANDS FOR LECTINS VIA GENETICALLYENCODED GLYCOPEPTIDE LIBRARIES Pavel I. Kitov, S. Ng, E. Lin, K. F. Tjhung, D. Ferrer-Vinals, A. Cruz Ramirez, R. Derda Alberta Glycomics Centre, Department of Chemistry, University of Alberta, Edmonton AB, Canada SESSION 15. Synthesis of carbohydrates III Versailles Hall Chair: David Bonnaffé, France 14:3015:00 Keynote Lecture KL14 DISRUPTION OF BACTERIAL MEMBRANES WITH AMPHIPHILIC AMINOSUGARS Micha Fridman Organic Chemistry, Tel Aviv University, Tel-Aviv, Israel 15:0015:20 SYNTHETIC CHEMISTRY OF THE CAPSULAR POLYSACCHARIDE OF Neisseria meningitidis SEROGROUP A D. V. Yashunsky, A. Black, Andrei V. Nikolaev Division of Biological Chemistry & Drug Discovery, College of Life Sciences, University of Dundee, Dundee, UK 15:2015:40 TRIAZOLE-LINKED LINEAR OLIGOMERS AND MACROCYCLES THAT INHIBIT Trypanosoma cruzi MACROPHAGE INVASION I. M. Ivanova,a V. L. Campo,b I. Carvalho,b Sergey A. Nepogodiev,a R. A. Fielda a Department of Biological Chemistry, John Innes Centre, Norwich, UK b Faculdade de Ciências Farmacêuticas de Ribeirão Preto, USP, Ribeirão Preto, Brazil 15:4016:00 SYNTHESIS OF DEFINED TEICHOIC ACID FRAGMENTS Daan van der Es,a N. A. Groenia,a W. F. J. Hogendorf,a N. Meeuwenoord,a D. Laverde,b J. Huebner,b G. A. van der Marel,a J. D. C. Codéea a Leiden University, Leiden, The Netherlands b University Medical Center Freiburg, Freiburg, Germany 16:00-17:00 Coffee-break / POSTER SESSION 2B 17 Place de Paris Eurocarb18 August 4, 2015 Scientific Program 17:00-18:25 PARALLEL SESSIONS 16-18 SESSION 16. Synthesis of carbohydrates: new approaches IV Tchaikovsky Hall Chair: Carlo Unverzagt, Germany 17:0017:30 Keynote Lecture KL15 GLYCOSIDIC BOND EXPANDED UNNATURAL CYCLIC OLIGOSACCHARIDES N. Jayaraman, Gour Chand Daskhan, Krishnagopal Maiti Department of Organic Chemistry, Indian Institute of Science, Bangalore, India 17:3017:50 NEW STRATEGIES TO OBTAIN GLYCOSYLPHOSPHATIDYILINOSITOL ANCHORS CONTAINING UNSATURATED LIPID CHAINS B. Y. Lee,a I. Vilotijevic,a P. H. Seeberger,a,b Daniel Varón Silvaa,b a Max Planck Institute of Colloids and Interfaces, Potsdam, Germany b Freie Universität Berlin, Berlin, Germany 17:5018:05 MODULAR STEREOSELECTIVE SYNTHESIS OF (1→2)-CDISACCHARIDES BASED ON THE SUZUKI-MIYAURA REACTION B. Oroszova,a J. Choutka,a R. Pohl,b Kamil Parkana a Department of Chemistry of Natural Compounds, University of Chemistry and Technology Prague, Prague, Czech Republic b Institute of Organic Chemistry and Biochemistry, Academy of Science of Czech Republic, v. v. i., Prague, Czech Republic 18:0518:20 H-BONDING PLAYING KEY ROLES IN TRANSESTERIFICATION OF HYDROXYL GROUP Hai Dong Huazhong University of Science & Technology, School of Chemistry & Chemical Engineering, Wuhan, P. R. China SESSION 17. Carbohydrates for medicine III Sponsored by GSK Shostakovich Hall Chair: Richard Furneaux, New Zealand 17:0017:30 Keynote Lecture KL16 RECENT TRENDS IN THE DESIGN OF GLYCOCONJUGATE VACCINES Roberto Adamo,a Q. Y. Hu,b F. Bertia a Novartis Vaccines & Diagnostics, Siena, Italy b Novartis Institues for Biomedical Research, Cambridge, Massachusetts, USA 17:3017:50 TOWARDS A ONE DOSE GLYCOCONJUGATE CHOLERA VACCINE Cyrille Grandjean,a T. K. Wade,b W. F. Wadeb a Unit Function & Protein Engineering UMR CNRS 6286UMR CNRS 6286, University of Sciences and Techniques, Nantes, France b Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, USA 18 Eurocarb18 August 4, 2015 Scientific Program 17:5018:10 THE UNIQUE CHEMISTRY OF VICINAL DI-O-SULFONATEMODIFIED SUGARS AND ITS APPLICATION IN GENERATING DIDOPYRANOSIDES SUITABLE FOR C. jejuni VACCINE DEVELOPMENT Rachel Hevey,a,b C.-C. Lingb a Department of Pharmaceutical Sciences, Universität Basel, Basel, Switzerland b Alberta Glycomics Centre, Department of Chemistry, University of Calgary, Calgary, Canada 18:1018:25 INHIBITION OF BACTERIAL ADHESION FOR A POTENTIAL TREATMENT OF CROHN’S DISEASE Thibaut Chalopin,a A. Sivignon,b D. Deniaud,a J. Bouckaert,c S. Gouina a LUNAM Université, CEISAM, Chimie Et Interdisciplinarité, Synthèse, Analyse, Modélisation, UMR CNRS 6230, UFR des Sciences et des Techniques, Nantes, France b Clermont Université, UMR 1071 Inserm/Université d’Auvergne, ClermontFerrand, France c Unité de Glycobiologie Structurale et Fonctionnelle (UGSF), UMR8576 du CNRS, Université Lille 1, Villeneuve d’Ascq, France SESSION 18. Synthesis of carbohydrates IV Versailles Hall Chair: Mikael Bols, Denmark 17:0017:30 Keynote Lecture KL17 SYNTHETIC AND BIOFUNCTIONAL STUDIES OF GLYCOCONJUGATES TOWARD IMMUNOREGULATION Koichi Fukase Department of Chemistry, Graduate School of Science, Osaka University, Toyonaka, Osaka, Japan 17:3017:50 A ONE-POT TANDEM APPROACH TOWARDS C-GLYCOSIDIC IMINOALDITOL BUILDING BLOCKS FOR BIOLOGICAL APPLICATIONS Tanja M. Wrodnigg Glycogroup, Graz University of Technology, Graz, Austria 17:5018:05 DESIGN AND SYNTHESIS OF MTAN- AND MTAP-INHIBITORS Oskar Hoff,a,b P. C. Tyler,a R. Furneaux,a T. M. Wrodniggb a Ferrier Research Institute, Victoria University of Wellington, Lower Hutt, New Zealand b Glycogroup, Graz University of Technology, Graz, Austria 18:0518:20 FUN WITH 3-IODO-KDO FLUORIDE DONORS – STEREOSPECIFIC SYNTHESIS OF COMPLEX LIPOPOLYSACCHARIDE INNER CORE FRAGMENTS Barbara Pokorny, P. Kosma University of Natural Resources and Life Sciences, Vienna, Austria 19:00-22:30 Symposium Dinner Place de Paris 19 Eurocarb18 August 5, 2015 Scientific Program WEDNESDAY, AUGUST 5, 2015 9:00-10:45 PARALLEL SESSIONS 19-21 SESSION 19. Synthesis of carbohydrates V Tchaikovsky Hall Chair: Zbigniew Witczak, USA 9:009:30 Keynote Lecture KL18 NEW PERSPECTIVES OF DESIGNER AMINOGLYCOSIDES: FROM FIXING HUMAN FAULTY GENES TO CONTROLLED GENE EXPRESSION Timor Baasov Schulich Faculty of Chemistry, Technion-IIT, Haifa, Israel 9:309:50 VIRTUAL SCREENING, SYNTHESIS AND ENZYMATIC EVALUATION OF 3-(β-D-GLUCOPYRANOSYL)-5-SUBSTITUTED1,2,4-TRIAZOLES FOR THE INHIBITION OF GLYCOGEN PHOSPHORYLASE Laszlo Somsák,a S. Kun,a J. Begum,c E. Szennyes,a É. Bokor,a L. Juhász,a T. Docsa,b P. Gergely,b J. M. Hayesc a Department of Organic Chemistry, University of Debrecen, Debrecen, Hungary b Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, Debrecen, Hungary c Centre of Materials Science, Division of Chemistry, University of Central Lancashire, Preston, UK 9:5010:10 THE CHALLENGING SYNTHESIS OF IMINOSUGAR-BASED GALACTOSIDE MIMICS AS POTENTIAL PHARMACOLOGICAL CHAPERONES FOR LYSOSOMAL GALACTOSIDASES Estelle Gallienne Boivineau, A. Biela-Banaś, S. Front, O. R. Martin ICOA, University of Orléans & CNRS, Orléans, France 10:1010:30 SYNTHESIS OF ORIGINAL IMINOSUGARS DERIVED FROM GlcNAc AND GalNAc TARGETING NAGLU AND NAGAL GLYCOSIDASES Yves Blériot,a Y. Jagadeesh,a C. Gauthier,a A. T. Tran,b J. Désiré,a A. Boraston,c M. C. Metcalf,d S. C. Garman,d M. Sollogoubb a IC2MP, UMR CNRS 7285, Poitiers, France b Sorbonne Universités, UPMC Univ Paris 06, UMR-CNRS 8232, IPCM, Paris, France c Department of Biochemistry and Microbiology, University of Victoria, Station CSC, Victoria, BC, Canada d Department of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA, USA 20 Eurocarb18 10:3010:45 August 5, 2015 Scientific Program 4(5)-ARYL-2-GLYCOPYRANOSYL-IMIDAZOLES, THE MOST POTENT GLUCOSE ANALOG INHIBITORS OF GLYCOGEN PHOSPHORYLASE Éva Bokor,a Cs. Koppány,a A. Szakács,a T. Docsa,b P. Gergely,b L. Somsáka a Department of Organic Chemistry, University of Debrecen, Debrecen, Hungary b Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, Debrecen, Hungary SESSION 20. Synthesis of carbohydrates: reaction mechanisms Shostakovich Hall Chair: Marek Chmielewski, Poland 9:009:30 Keynote Lecture KL19 ALL-cis UNDERSTANDING CONFORMATIONAL BEHAVIOR FOR cis-GLYCOSYLATIONS Jeroen D. C. Codée Leiden Institute of Chemistry, Universiteit Leiden, Leiden, The Netherlands 9:309:50 MECHANISTIC STUDIES OF PYRANOSIDE-INTO-FURANOSIDE REARRANGEMENT BY MEANS OF QUANTUM CHEMISTRY METHODS Alexey G. Gerbst, V. B. Krylov, D. A. Argunov, D. Z. Vinnitskiy, S. A. Verkhnyatskaya, N. E. Ustyuzhanina, N. E. Nifantiev Laboratory of Glycoconjugate Chemistry, N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia 9:5010:10 -MANNOSYLATION MECHANISM REVISITED Christian M. Pedersen, M. Heuckendorff, P. Bols, C. Barry, T. G. Frihed, M. Bols University of Copenhagen, Copenhagen, Denmark 10:1010:30 UNDERSTANDING REACTIVITY AND STEREOSELECTIVITY OF GLYCOSYL DONORS: IMPORTANCE OF SOLUTION STRUCTURE Leonid Kononov, A. Orlova N. D. Zelinsky Institute of Organic Chemistry, Moscow, Russia 10:3010:45 COMPUTATIONAL APPROACHES REGARDING THE CHEMICAL NATURE OF ION PAIRS FORMED UPON GLYCOSIDE SYNTHESIS Takashi Hosoya, P. Kosma, T. Rosenau University of Natural Resources and Life Sciences, Vienna, Austria SESSION 21. Structure of carbohydrates Versailles Hall Chair: Alfred French, USA 9:009:30 Keynote Lecture KL20 CHALLENGES IN LIPOPOLYSACCHARIDE RESEARCH Otto Holst Research Center Borstel, Borstel, Germany 9:309:45 STRUCTURE OF O-SPECIFIC POLYSACCHARIDES FROM SOME MARINE GRAM-NEGATIVE BACTERIA Maxim S. Kokoulin, S. V. Tomshich, N. A. Komandrova G. B. Elyakov Pacific Institute of Bioorganic Chemistry, Vladivostok, Russia 21 Eurocarb18 August 5, 2015 Scientific Program 9:4510:00 STRUCTURAL STUDIES OF THE O-SPECIFIC POLYSACCHARIDE OF Azospirillum halopraeferens AU4 Elena N. Sigida,a A. S. Shashkov,b Y. P. Fedonenko,a N. P. Arbatsky,b E. L. Zdorovenko,b S. A. Konnova,c Y. A. Knirel,b V. V. Ignatova a Institute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences, Saratov, Russia b N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia c Chernyshevsky Saratov State University, Saratov, Russia 10:0010:15 THE INFLUENCE OF CELL WALL COMPOSITION AND STRUCTURE ON POTATO DIGESTIBILITY Jovyn Ng,a B. Flanagan,b M. Gidley,b E. O’Donoghue,a D. Brummell,a S. Mishra,a J. Monroa a The New Zealand Institute for Plant & Food Research Limited, Palmerston North, New Zealand b Centre for Nutrition & Food Sciences, University of Queensland, Brisbane, Australia 10:1510:30 THE PRINCIPLE OF POLYSACCHARIDE GELS Masakuni Tako Department of Subtropical Bioscience and Biotechnology, University of the Ryukyus, Nishihara, Okinawa 903-0213, Japan Health and Longevity Research Laboratory, Integrated Innovation Research Center, University of the Ryukyus, Nishihara, Okinawa, Japan 10:3010:45 POLYSACCHARIDES FROM FRUITING BODIES OF Pleurotus ostreatus: ISOLATION AND STRUCTURAL CHARACTERIZATION Ekaterina Baeva, A. Synytsya, J. Čopíková Department of Carbohydrates and Cereals, University of Chemistry and Technology, Prague, Czech Republic 10:45-11:15 Coffee-break Place de Paris 11:15-12:35 PARALLEL SESSIONS 22-24 SESSION 22. Synthesis of carbohydrates VI Tchaikovsky Hall Chair: N. Jayaraman, India 11:1511:45 Keynote Lecture KL21 TOTAL SYNTHESIS OF PERIPLOSIDE A, A UNIQUE PREGNANE HEXASACCHARIDE WITH POTENT IMMUNOSUPPRESSIVE EFFECTS Biao Yu, X. Zhang State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China 22 Eurocarb18 August 5, 2015 Scientific Program 11:4512:00 SYNTHESIS OF OLIGOSACCHARIDES RELATED TO THE O-SPECIFIC POLYSACCHARIDE OF Shigella sonnei Hélène Pfister,a,b,c,d J. Paoletti,a,b L. A. Mularda,b a Unité de Chimie des Biomolécules, Département de Biologie Structurale et Chimie, Institut Pasteur, Paris, France b CNRS UMR 3523, Institut Pasteur, Paris, France c Université Paris Descartes Sorbonne Paris Cité, Paris, France d Present adress: Molecular Pharmacy, Department of Pharmaceutical Sciences, Universität Basel, Basel, Switzerland 12:0012:15 CONVERGENT SYNTHESIS OF Shigella flexneri 3A PENTA- TO ICOSASACCHARIDES Zhaoyu Hu, A. F. Bongat-White, L. A. Mulard Institut Pasteur, Chimie des Biomolécule, Paris, France CNRS UMR3523, Institut Pasteur, Paris, France 12:1512:30 CHEMICAL SYNTHESIS OF FRAGMENTS OF THE O-ANTIGENS OF Shigella flexneri 1A AND 1B WITH FOCUS ON THE BRANCHING PATTERN Yann Le Guen,a,b,c J. M. Hargreaves,a,b L. A. Mularda,b a Institut Pasteur, Chimie des Biomolécules, Paris, France b CNRS UMR3523, Institut Pasteur, Paris, France c Université Paris Descartes Sorbonne Paris Cité, Institut Pasteur, Paris, France SESSION 23. Carbohydrates for medicine IV Shostakovich Hall Chair: Nicolai Bovin, Russia 11:1511:45 Keynote Lecture KL22 HEPARAN SULFATE, SIALIC ACID AND BLOOD GROUP A: PATHOGENESIS AND TREATMENT OF SEVERE Plasmodium falciparum MALARIA Mats Wahlgren MTC, Karolinska Institutet, Stockholm, Sweden 11:4512:05 SULFATED POLYSACCHARIDE OF RED MICROALGAE: SULFATE THE BIOACTIVE SITE Shoshana Arad Department of Biotechnology Engineering, Ben-Gurion University of the Negev, Beer-Sheva, Israel 12:0512:20 ETHNOBOTANICAL PLANTS OF AFRICA: FROM TRADITIONAL USE TOWARD BIOACTIVE POLYSACCHARIDES AS DRUGS OF TOMORROW Cedric Delattre,a,b B. Petera,a,b,c Z. Boual,d G. Pierre,a,b F. Benaoun,d T. Chouana,d C. Gardarin,a,b M. DidiOuldElHadj,d T. A. Fenoradosoa,c P. Michauda,b a Université Clermont Auvergne, Université Blaise Pascal, Institut Pascal, Clermont-Ferrand, France b CNRS, UMR 6602, IP, Aubière, France c Faculté des Sciences de l'Université d'Antsiranana, Antsiranana, Madagascar d Université Ouargla, Laboratoire Protection des Ecosystèmes en Zones Arides et Semi-arides, Ouargla, Algeria 23 Eurocarb18 12:2012:35 August 5, 2015 Scientific Program MARINE BACTERIAL POLYSACCHARIDES AS GLYCOSAMINOGLYCAN-MIMETICS FOR CARTILAGE REGENERATIVE MEDICINE Sylvia Colliec-Jouault,a B. Halgand,b A. Zykwinska,a C. Sinquin,a J. Ratiskol,a J. Le Bideau,c P. Weiss,b C. Vinatier,b J. Guicheuxb a Ifremer, EM3B, Nantes, France b Inserm Université de Nantes UMRS 791, LIOAD, Nantes, France c IMN, Université de Nantes CNRS UMR 6502, Nantes, France SESSION 24. Enzymatic synthesis of carbohydrates Versailles Hall Chair: László Somsák, Hungary 11:1511:40 SUGAR-COATED SENSOR CHIP AND NANOPARTICLE SURFACES FOR THE IN VITRO ENZYMATIC SYNTHESIS OF STARCH-LIKE MATERIALS E. C. O'Neill,a A. M. Rashid,a C. E. Stevenson,a A.-C. Hetru, A. P. Gunning,b M. Rejzek,a S. A. Nepogodiev,a S. Bornemann,a D. M. Lawson,a Rob A. Fielda a Department of Biological Chemistry, John Innes Centre, Norwich NR4 7UH, UK b Institute of Food Research, Norwich Research Park, Norwich NR4 7UA, UK 11:4012:00 C-GLYCOSYLTRANSFERASES: FROM MECHANISTIC INSIGHT TO SYNTHETIC APPLICATION IN FLAVONOID GLYCOSYLATION Alexander Gutmann,a L. Bungaruang,a B. Nidetzkya,b a Institute of Biotechnology and Biochemical Engineering, Graz University of Technology, NAWI Graz, Graz, Austria b Austrian Centre of Industrial Biotechnology, Graz, Austria 12:0012:20 EXPLORING SMALL MOLECULE PHOSPHORYLATION USING GLYCOGEN-POLYIODIDE COMPLEXES X. C. Duan, H. Chen, F. F. Liu, S. Wei, H. B. Song, Y. M. Lü, Q. Li, Y. Chen, Z. P. Cai, L. Liu, Josef Voglmeir Glycomics and Glycan Bioengineering Research Center (GGBRC), College of Food Science and Technology, Nanjing Agricultural University, Nanjing, China 12:2012:35 TURNING BULK SUGARS INTO PREBIOTICS: HIGHLY EFFICIENT ONE-STEP ENZYMATIC CONVERSION OF SUCROSE AND GLUCOSE INTO KOJIBIOSE Tom Verhaeghe, K. De Winter, T. Desmet Centre for Industrial Biotechnology and Biocatalysis, Department of Biochemical and Microbial Technology, Ghent University, Ghent, Belgium 13:00 Optional Sightseeing Tours 24 Eurocarb18 August 6, 2015 Scientific Program THURSDAY, AUGUST 6, 2015 9:00-10:30 PLENARY SESSION 4 9:009:45 Plenary Lecture PL07 Tchaikovsky Hall Chair: Göran Widmalm, Sweden FUCOIDANS: STRUCTURAL DIVERSITY OF SULFATED POLYSACCHARIDES OF THE BROWN ALGAE Anatolii I. Usov N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia 9:4510:30 Plenary Lecture PL08 Chair: Otto Holst, Germany STRUCTURAL ANALYSIS OF THE END-GROUPS IN BACTERIAL POLYSACCHARIDES Evgeny Vinogradov National Research Council of Canada, Ottawa, Canada 10:30-11:00 Coffee-break Place de Paris 11:00-12:40 PARALLEL SESSIONS 25-27 SESSION 25. Synthesis of carbohydrates: new approaches V Tchaikovsky Hall Chair: Andrei Nikolaev, UK 11:0011:30 Keynote Lecture KL23 THE CYCLIC CONUNDRUM SOLVED: SYNTHESIS AND APPLICATIONS OF SITE-SELECTIVELY MODIFIED CYCLODEXTRINS WITH UP TO 6 DIFFERENT FUNCTIONS Matthieu Sollogoub Sorbonne Universités, UPMC Univ Paris 06, IUF, Institut Parisien de Chimie Moléculaire (UMR NRS 8232), Paris, France 11:3011:55 CONTROLLING CARBOHYDRATE REACTIVITY WITH A MOLECULAR LEVER J. I. Olsen, C. M. Pedersen, Mikael Bols University of Copenhagen, Copenhagen, Denmark 25 Eurocarb18 August 6, 2015 Scientific Program 11:5512:10 AN INCLUSION-ASSISTED REGIOSELECTIVE SYNTHESIS OF FOLATE-APPENDED CYCLODEXTRINS Milo Malanga,a A. Darcsi,b S. Béni,c G. Benkovics,a J. Szeman,a T. Sohajda,a L. Szente,a K. Yannakopouloud a CycloLab, Cyclodextrin R&D Ltd, Budapest, Hungary b Semmelweis University, Department of Pharmaceutical Chemistry, Budapest Hungary c Semmelweis University, Department of Pharmacognosy, Budapest, Hungary d Institute of Nanoscience & Nanotechnology, NCSR "Demokritos", Athens, Greece 12:1012:25 DO WE NEED BENZYL PROTECTION FOR 1,2-cisGLYCOSYLATION? Polina I. Abronina, A. I. Zinin, V. V. Tereshina, V. I. Torgov, L. O. Kononov N. D. Zelinsky Institute of Organic Chemistry, Moscow, Russia 12:2512:40 ANOMERIC DEACETYLATION AND BY-PRODUCT REMOVAL WITH 3-(DIMETHYLAMINO)-1-PROPYL AMINE Mads Heuckendorff, S. M. Andersen, H. H. Jensen Department of Chemistry, Aarhus University, Aarhus C, Denmark SESSION 26. Carbohydrate-protein interactions II Shostakovich Hall Chair: Beat Ernst, Switzerland 11:0011:30 Keynote Lecture KL24 BACTERIAL LECTINS AND DYNAMICS OF GLYCOLIPIDS IN HOST MEMBRANES Anne Imberty Centre de Recherche sur les Macromolécules Végétales, CNRS and Université Grenoble Alpes, Grenoble, France 11:3011:50 MODIFICATION OF TRICYCLIC GLYCOFUSED COMPOUNDS AND THEIR BINDING TO AMYLOID Β PEPTIDES Barbara La Ferla,a C. Airoldi,a G. D’Orazio, a B. Richichi,b C. Guzzi,a V. Baldoneschi,b C. Nativi,b F. Nicotraa a University of Milano-Bicocca, Dep. Biotechnology and Bioscience, Milan, Italy b University of Firenze, Dep. Chemistry “Ugo Schiff”, Sesto Fiorentino (FI), Italy 11:5012:10 CONSTRUCTION OF RESPIRATORY MUCIN MICROARRAY AS A SCREENING MODEL TO STUDY THE ROLE OF GLYCOSYLATION IN CYSTIC FIBROSIS Marie Le Berre,a C. Tuite,a J. Q. Gerlach,a M. O’Mahony,c M.E. Gallagher,d S. D. Carrington,d J. A. Lane,e R. M. Hickey,e M. Kilcoyne,a,b L. Joshia a Glycoscience Group, National Centre for Biomedical Engineering Science, National University of Ireland, Galway, Ireland b Microbiology, School of Natural Sciences, National University of Ireland, Galway, Ireland c Galway University Hospital, Galway, Ireland d Veterinary Science Centre, University College Dublin, Belfield, Dublin 4, Ireland e Teagasc, Moorepark Food Research Centre,Fermoy, Co. Cork, Ireland 26 Eurocarb18 August 6, 2015 Scientific Program 12:1012:25 IDENTIFICATION OF HOST RECEPTORS FOR Staphylococcus aureus BIOFILM Andrea Flannery,a,b J. P. O’Gara,a M. Kilcoyneb a Microbiology, School of Natural Sciences, National University of Ireland, Galway, Ireland b Glycoscience Group, National Centre for Biomedical Engineering Science, National University of Ireland, Galway, Ireland 12:2512:40 THE EFFECT OF MICRODOMAIN FORMATION ON THE SPATIOTEMPORAL DYNAMICS OF MEMBRANE GLYCANS Leonhard Möckl,a A. K. Horst,b K. Kolbe,c Th. K. Lindhorst,c Ch. Bräuchlea a Department of Physical Chemistry, Ludwig Maximilian University of Munich, Munich, Germany b Institute for Experimental Immunology and Hepatology, University Medical Center Hamburg, Hamburg, Germany c Otto Diels Institute of Organic Chemistry, Christiana Albertina University of Kiel, Kiel, Germany SESSION 27. Carbohydrate structure analysis: new approaches III Versailles Hall Chair: Evgeny Vinogradov, Canada 11:0011:30 Keynote Lecture KL25 STRUCTURE, CONFORMATION AND INTERACTIONS OF GLYCANS Göran Widmalm Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, Stockholm, Sweden 11:3011:45 NMR SPECTROSCOPY AND MOLECULAR DYNAMICS SIMULATION STUDIES OF TWO E. coli O-ANTIGEN POLYSACCHARIDES Pilar Blasco,a O. Engström,a D. S. Patel,b E. L. Wu,b W. Im,b G. Widmalma a Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, Stockholm, Sweden b Department of Molecular Biosciences and Center for Bioinformatics, The University of Kansas, Lawrence, Kansas, USA 11:4512:05 NMR STUDY ON Burkholderia pseudomallei CAPSULAR POLYSACCHARIDE RECOGNITION BY A MONOCLONAL ANTIBODY Antonio Molinaro Department of Chemical Sciences, Università di Napoli Federico II, Naples, Italy 27 Eurocarb18 August 6, 2015 Scientific Program 12:0512:25 INTERACTION BETWEEN THE RECOGNITION PROTEIN HEMAGGLUTININ, OF THE AVIAN INFLUENZA A VIRUS, WITH GLYCAN CELL SURFACE RECEPTORS: A JOINED MD SIMULATION AND NMR STRUCTURAL INVESTIGATION Stefano Elli,a E. Macchi,a T. R. Rudd,b R. Raman,c Z. Shriver,c R. Sasisekharan,c G. Torri,a M. Guerrini a a Istituto di Ricerche Chimiche e Biochimiche “G. Ronzoni”, Milano, Italy b Diamond Light Source Ltd., Diamond House, Harwell Science and Innovation Campus, Didcot, Oxfordshire, UK c Department of Biological Engineering, Koch Institute of Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA 12:2512:40 STRUCTURE AND ANTICOAGULANT ACTIVITY OF A HIGHLY RAMIFIED SULFATED ARABINAN FROM GREEN SEAWEED Cladophora falklandica Marina Ciancia,a,b P. X. Arata,a M. P. Raffo,c A. M. Lauricella,d I. Quintanad a Cátedra de Química de Biomoléculas, Departamento de Biología Aplicada y Alimentos, Facultad de Agronomía, Universidad de Buenos Aires, Buenos Aires, Argentina b CIHIDECAR-CONICET, Departamento de Química Orgánica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, Buenos Aires, Argentina c Centro Nacional Patagónico-CONICET, Puerto Madryn, Chubut, Argentina d Laboratorio de Hemostasia y Trombosis, Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, Buenos Aires, Argentina 12:40-14:00 Lunch Place de Paris 14:00-15:45 PARALLEL SESSIONS 28-30 SESSION 28. Engineering of glycan presentation Tchaikovsky Hall Chair: Anne Imberty, France 14:0014:30 Keynote Lecture KL26 ORGANIZING MULTIVALENCY IN CARBOHYDRATE RECOGNITION Thisbe K. Lindhorst Christiana Albertina University of Kiel, Kiel, Germany 14:3014:50 NOVEL CYCLOOCTYNES WITH EXCITING PHYSICAL PROPERTIES FOR THE BIOORTHOGONAL LABELING OF GLYCOCONJUGATES Frederic Friscourt,a,b P. A. Ledin,b R. Steet,b C. J. Fahrni,c G.-J. Boonsb a Institut Européen de Chimie et Biologie, CNRS UMR 5287 – INCIA, Pessac, France b Complex Carbohydrate Research Center, Athens, Georgia, USA c Georgia Institute of Technology, Atlanta, Georgia, USA 28 Eurocarb18 August 6, 2015 Scientific Program 14:5015:10 BIOORTHOGONAL LABELING OF CELLULAR CARBOHYDRATES WITH THE INVERSE-ELECTRON-DEMAND DIELS-ALDER REACTION Valentin Wittmann University of Konstanz, Department of Chemistry, 78457 Konstanz, Germany 15:1015:30 IMIDAZOLIUM-BASED TAGS AS NON COVALENT TOOLS FOR LIVE CELL LABELLING M. Carmen Galan,a D. Benito-Alifonso,a S. Tremell,b J. Sadler,a M. Berryb a School of Chemistry, University of Bristol, Cantock’s Close, Bristol, UK b School of Physics, University of Bristol, NSQI, Tyndall Ave, Bristol, UK 15:3015:45 A NEW SHOT-GUN APPROACH FOR THE MULTIVALENT PRESENTATION OF PARASITE-DERIVED CARBOHYDRATES ON GOLD NANOPARTICLES Fabrizio Chiodo,a,b D. L. Nguyen,a C. H. Hokke a a Leiden University Medical Center, Department of Parasitology, Leiden, The Netherlands b Leiden Institute of Chemistry, Bio-organic Synthesis Department, Leiden, The Netherlands SESSION 29. Carbohydrate-active enzymes II Shostakovich Hall Chair: Michael Ferguson, UK 14:0014:20 SUBSTRATE SPECIFICITY OF CHITIN DEACETYLASES: HOW LOOPS DEFINE THE DE-N-ACETYLATION PATTERN X. Biarnés,a H. Aragunde,a D. Albesa-Jové,b M. E. Guerin,b Antoni Planasa a Laboratory of Biochemistry, Institut Químic de Sarrià, Universitat Ramon Llull, 08017 Barcelona, Spain b Unidad de Biofísica, Centro Mixto CSIC-Universidad del País Vasco/Euskal Herriko Unibertsitatea, 48940 Bizkaia, Spain 14:2014:40 ACTION OF AN AA9-TYPE LYTIC POLYSACCHARIDE MONOOXYGENASE ON THE CELLULOSE SURFACE AND ITS EFFECT ON CELLULASE HYDROLYTIC EFFICENCY Manuel Eibinger,a T. Ganner,b H. Plank,b B. Nidetzkya,c a Institute of Biotechnology and Biochemical Engineering, Graz University of Technology, Graz, Austria b Institute of Electron Microscopy and Nanoanalysis, Graz University of Technology, Graz, Austria c Austrian Centre of Industrial Biotechnology, Graz, Austria 29 Eurocarb18 August 6, 2015 Scientific Program 14:4015:00 NEW INSIGHT INTO THE DESIGN OF TRANSGLYCOSYLASES IN RETAINING GLYCOSIDE HYDROLASES B. Bissaro,a,b,c J. Durand,a,b,c X. Biarnés,d P. Monsan,a,b,c,e A. Planas,d S. Bozonnet,a,b,c Regis Fauré,a,b,c M. J. O'Donohuea,b,c a Université de Toulouse, INSA, UPS, INP, LISBP, Toulouse, France b INRA, UMR792, Ingénierie des Systèmes Biologiques et des Procédés, Toulouse, France c CNRS, UMR5504, Toulouse, France d Laboratory of Biochemistry, Institut Químic de Sarrià, Universitat Ramon Llull, Barcelona, Spain e Toulouse White Biotechnology, UMS INRA/INSA 1337, UMS CNRS/INSA 3582, Toulouse, France 15:0015:20 INDUCED FIT VERSUS CONFORMATIONAL SELECTION IN A GLYCOSYLTRANSFERASE STRUCTURE. INSIGHTS FROM METADYNAMICS SIMULATIONS Xevi Biarnés,a J. Romero-García,a D. Albesa-Jové,b M. E. Guerin,b A. Planasa a Laboratory of Biochemistry, Institut Químic de Sarrià, Universitat Ramon Llull, Barcelona, Spain b Unidad de Biofísica, Centro Mixto Consejo Superior de Investigaciones Científicas-Universidad del País Vasco, Bizkaia, Spain 15:2015:40 NOVEL COLOURIMETRIC SUBSTRATES FOR THE MEASUREMENT OF ENDO-ACTING CARBOHYDRATE HYDROLASES David Mangan, B. McCleary, V. McKie, R. Ivory Megazyme International, Bray Business Park, Bray, Co. Wicklow, Ireland SESSION 30. Carbohydrate structure analysis: new approaches IV Versailles Hall Chair: Robert Woods, USA 14:0014:30 Keynote Lecture KL27 CONFORMATIONAL MAPPING OF MALTOSE WITH QUANTUM MECHANICS Alfred D. French,a M. Santiago Cintrónb a ICS2016, New Orleans, Louisiana, USA b Southern Regional Research Center, U. S. Department of Agriculture, New Orleans, Louisiana, USA 14:3014:50 EXPERIMENTAL AND COMPUTATIONAL INSIGHTS INTO STRUCTURE AND NMR SPIN-SPIN COUPLING CONSTANTS IN HEPARIN OLIGOSACCHARIDES Miloš Hricovíni,a P.-A. Driguez,b O. L. Malkinac a Institute of Chemistry, Slovak Academy of Sciences, 845 38 Bratislava, Slovakia b Sanofi, Early to Candidate Unit, 1 Avenue Pierre Brossolette, 91385 Chilly-Mazarin Cedex, France c Institute of Inorganic Chemistry, Slovak Academy of Sciences, 845 36 Bratislava, Slovakia 30 Eurocarb18 August 6, 2015 Scientific Program 14:5015:10 GODESS SOFTWARE: SIMULATION OF THE 13C, 1H AND 2D NMR SPECTRA OF CARBOHYDRATES R. Kapaev,a Philip Toukachb a Higher Chemical College of the Russian Academy of Sciences, Moscow, Russia b N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia 15:1015:25 CONFORMATIONAL ANALYSIS OF GLYCOSYLPHOSPHATIDYLINOSITOLS (GPIS) USING PARAMAGNETIC-NMR TECHNIQUES Monika Garg,a M. Santer,b D. Varón Silvaa a Max Planck Institute of Colloids and Interfaces, Biomolecular Systems, Berlin, Germany b Max Planck Institute of Colloids and Interfaces, Theory and Bio-Systems, Potsdam, Germany 15:2515:40 ANALYTICAL CHARACTERIZATION OF HUMAN MILK OLIGOSACCHARIDES BY LC-MS, GC-MS AND NMR Szabolcs Béni,a R. Balogh,b A. Tóth,a M. Grabaricsa a Semmelweis University, Department of Pharmacognosy, Budapest, Hungary b Semmelweis University, Department of Pharmaceutical Chemistry, Budapest, Hungary 15:45-16:15 Coffee-break 16:15 Place de Paris CLOSING SESSION Tchaikovsky Hall Presentation of the 19th European Carbohydrate Symposium (Eurocarb19) Presentation of the 28th International Carbohydrate Symposium (ICS 2016) Closing Remarks 31 POSTERS 32 Eurocarb18 August 3, 2015 Poster Session 1 MONDAY, AUGUST 3, 2015 POSTER SESSION 1 Place de Paris 10:3011:30 SESSION 1A. Authors of posters with odd numbers stand by their posters. 16:0017:00 SESSION 1B. Authors of posters with even numbers stand by their posters. 1. GENERATION OF LONG-LIVED GLYCOSYL CATIONS ALLOWING THEIR STRUCTURAL STUDY Yves Blériot,a A. Martin,a A. Arda,b N. Probst,a J. Désiré,a A. Mingot,a J. Jiménez-Barbero,b S. Thibaudeaua a IC2MP, UMR CNRS 7285, Poitiers, France b CIC bioGUNE, Derio-Bizkaia, Spain 2. ORGANOBASE-CATALYZED REGIOSELECTIVE BENZOYLATION OF DIOLS AND CARBOHYDRATES Zhichao Pei,a Y. Lu,a H. Xu,a C. Hou,a Y. Pei,a H. Dongb a College of Science, Northwest A&F University, Yangling, Shaanxi, China b School of Chemistry & Chemical Engineering, Huazhong University of Science & Technology, Wuhan, China 3. THIO-CLICK AND DOMINO APPROACHES TO CARBOHYDRATE HETEROCYCLES Zbigniew J. Witczak, R. Bielski, T. Grove Department of Pharmaceutical Sciences, Nesbitt College of Pharmacy, Wilkes University, Wilkes-Barre, Pennsylvania, USA 4. APPROACHES TO THE SYNTHESIS OF CHALLENGING GLYCOSYL THIOLS Elizabeth J. Grayson,a B. G. Davisb a Department of Chemistry, Durham University, Durham, UK b Chemistry Research Laboratory, University of Oxford, Oxford, UK 5. REGIOSELECTIVE O-ACYLATIONS AND ALKYLATIONS OF SUCRALOSE AND -LACTOSIDE DERIVATIVES S. E. Soliman,a,b S. A. Shehata,a R. W. Bassily,a R. I. El-Sokkary,a Mina A. Nasheda a Department of Chemistry, Faculty of Science, Alexandria University, Alexandria, Egypt bNIDDK, LBC, Section on Carbohydrates, National Institutes of Health, Bethesda, Maryland, USA 6. EFFECTIVE 4-OH GLYCOSYL ACCEPTOR DERIVATIVES OF D-GLUCOSAMINE WITH NOVEL N-PROTECTING GROUP Sergey S. Pertel, V. Y. Osel’skaya, S. A. Seryi, E. S. Kakayan V. I. Vernadsky Crimean Federal University, Simferopol, Russia 7. GLUCOSE DERIVED DIOXO-MOLYBDENUM (VI) COMPLEXES: SYNTHESIS, CHARACTERISATION AND THEIR STUDIES ON SULPHIDE OXIDATION Mohammed Noorullah Baig, A. K. Sah Department of Chemistry, Birla Institute of Technology and Science, Pilani, Pilani Campus, Rajasthan 333031, India 33 Eurocarb18 August 3, 2015 Poster Session 1 8. A SIMPLE ROUTE TO 2’-O-ACETYL GLYCOPYRANOSIDES Marina O. Nagornaya, E. V. Stepanova National Research Tomsk Polytechnic University, Tomsk, Russia 9. SYNTHESIS OF C-(-D-GLYCOPYRANOSYL)METHYL-SULFIDES: METALFREE COUPLING OF ANHYDRO-ALDOSE TOSYLHYDRAZONES WITH ALIPHATIC AND AROMATIC THIOLS Timea Kaszás, M. Tóth, L. Somsák Department of Organic Chemistry, University of Debrecen, Debrecen, Hungary 10. THE FIRST SYNTHESIS OF BROMO- AND CHLOROMETHYL PHENYL GLUCOPYRANOSIDES Elena V. Stepanova, M. O. Nagornaya, D. A. Romanova Tomsk Polytechnic University, Tomsk, Russia 11. SYNTHESIS OF 5-(-D-GLUCOPYRANOSYL)-1,3-DISUBSTITUTED- AND 3-(-D-GLUCOPYRANOSYL)-1,5-DISUBSTITUTED-1,2,4-TRIAZOLES Erzsebet K. Szabó, A. Páhi, L. Somsák Department of Organic Chemistry, University of Debrecen, Debrecen, Hungary 12. BORON – WITTIG REACTION IN CARBOHYDRATE CHEMISTRY Kristyna Řepková, K. Parkan Department of Chemistry of Natural Compounds, UCT Prague, Prague, Czech Republic 13. SYNTHESIS OF C-(-D-GLUCOPYRANOSYL)FORMAMIDINE AND ITS TRANSFORMATION INTO 2-(-D-GLUCOPYRANOSYL)-PYRIMIDINES Eszter Szennyes, É. Bokor, L. Somsák Department of Organic Chemistry, University of Debrecen, Debrecen, Hungary 14. DIRECT CATALYTIC GLYCOSYLATION WITH 2-ACETAMIDO-2-DEOXY GALACTOSYL DONORS Mikkel H. S. Marqvorsen, M. R. Rasmussen, S. K. Kristensen, H. H. Jensen Aarhus University, Aarhus, Denmark 15. FLUORESCENT CYCLODEXTRINS WITH NITRIC OXIDE RELEASING ABILITY Gabor Benkovics,a M. Malanga,a E. Fenyvesi,a S. Sortinob a CycloLab, Cyclodextrin R&D Ltd, Budapest, Hungary b University of Catania, Department of Drug Sciences, Catania, Italy 16. NOVEL AND STEREOSELECTIVE CARBOCYCLIZATION OF CARBOHYDRATE-DERIVED LACTONE ACETALS Christinne Hedberg, M. Estrup, E. Eikeland, H. H. Jensen Department of Chemistry, Aarhus University, Aarhus, Denmark 17. TOWARDS SYNTHESIS OF AN IDRAPARINUX ANALOGUE BEARING A SECONDARY SULFONATOMETHYL MOIETY Dabiel Eszenyi,a,b M. Herczeg,a E. Mező,a A. Borbása a Department of Pharmaceutical Chemistry, University of Debrecen, Debrecen, Hungary b Department of Organic Chemistry, University of Debrecen, Debrecen, Hungary 34 Eurocarb18 August 3, 2015 Poster Session 1 18. DEVELOPMENT OF A SYNTHETIC STRATEGY FOR THE ONE-POT SYNTHESIS OF NON-NATURAL OLIGOSACCHARIDES IN AQUEOUS MEDIA Anne Brinkø, H. H. Jensen Aarhus University, Department of Chemistry, Aarhus C, Denmark 19. SYNTHESIS OF A TETRASACCHARIDE CORRESPONDING TO THE INNER PART OF N-LINKED GLYCOPROTEINS Hani Mobarak, J. Rönnols, G. Widmalm Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, Stockholm, Sweden 20. SYNTHESIS AND EVALUATION OF IMINOSUGARS AS THERAPEUTICS IN KRABBE DISEASE Agnete H. Viuff,b C. H. Hill,a S. J. Spratley,a S. Salamone,b S. H. Christensen,b R. J. Read,a N. W. Moriarty,c H. H. Jensen,b J. E. Deanea a Department of Haematology, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK b Department of Chemistry, Aarhus University, 8000 Aarhus C., Denmark c Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, USA 21. ALTERNATIVE PROCEDURE FOR THE INTRODUCTION OF PROTECTIVE GROUPS IN THE SYNTHESIS OF REPEATED UNIT HIB Jose A. Ruiz, Y. Gonzalez Diaz, E. Sánchez, M. C. Rodríguez, V. Vérez Carlos J. Finlay Institute, La Habana, Cuba 22. SYNTHESIS OF DISACCHARIDES RELATED TO ENTEROCOCCAL DIHETEROGLYCAN EMPLOYING PYRANOSIDE-INTO-FURANOSIDE REARRENGEMENT Vadim B. Krylov,a D. A. Argunov,a J. Huebner,b O. Holst,c N. E. Nifantieva a N. D. Zelinsky Institute of Organic Chemistry RAS, Moscow, Russia b Division of Pediatric Infectious Diseases, Hauner Children´s Hospital, LudwigsMaximilian University, Munich, Germany c Research Center Borstel, Leibniz-Center for Medicine and Biosciences, Borstel, Germany 23. A CONVERGENT STRATEGY FOR ASSEMBLY OF LINEAR 1→5 LINKED ARABINANS RELATED TO FRAGMENTS OF MYCOBACTERIAL LIPOARABINOMANNAN Maria V. Panova,a,b N. M. Podvalnyy,a E. L. Okun,a V. I. Torgov,a L. O. Kononova a N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia bThe Higher Chemical College of the Russian Academy of Sciences, Moscow, Russia 24. SYNTHESIS OF SPACER-ARMED OLIGOSACCHARIDES RELATED TO THE O-SPECIFIC POLYSACCHARIDE OF Klebsiella pneumoniae EMPLOYING PYRANOSIDE-INTO-FURANOSIDE REARRENGEMENT Stella A. Verkhnyatskaya,a V. B. Krylov,a H.-Ch. Siebert,b N. E. Nifantieva a Laboratory of Glycoconjugate Chemistry, N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia b RI-B-NT Research Institute of Bioinformatics and Nanotechnology, Kiel, Germany 35 Eurocarb18 August 3, 2015 Poster Session 1 25. SYNTHESIS OF Lea RELATED DI- AND TRISACCHARIDE FRAGMENTS OF THE O-POLYSACCHARIDE FROM PLANT-GROWTH-PROMOTING RHIZOBACTERIA Azospirillum brasilense Sp7 Denis A. Romashin, P. I. Abronina, A. I. Zinin, A. O. Chizhov, L. O. Kononov N. D. Zelinsky Institute of Organic Chemistry, Moscow, Russia 26. CONVERGENT SYNTHESIS OF ISOMERIC HETEROSACCHARIDES RELATED TO THE FRAGMENTS OF GALACTOMANNAN FROM Aspergillus fumigatus Dmitry A. Argunov, V. B. Krylov, N. E. Nifantiev Laboratory of Glycoconjugate Chemistry, N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia 27. NEW GLYCOSYLATED GLYCEROLIPIDS INDUCE PREFERENTIAL DAMAGE OF TUMOR CELLS Nina G. Morozova,a E. V. Shmendel,a G. A. Timofeev,a A. A. Timakova,a O. V. Sogreeva,a A. A. Markova,b T. S. Kubasova,a A. S. Petrova,a M. A. Maslov,a A. A. Shtilb a M. V. Lomonosov Moscow State University of Fine Chemical Technologies, Moscow, Russia b Blokhin Cancer Center, Moscow, Russia 28. SYNTHESIS OF ANALOGUES OF UNDECAPRENYL DIPHOSPHATE SUGARS CONTAINING CHROMOPHORE GROUPS FOR STUDIES OF THE SECOND STEP OF BACTERIAL O-ANTIGEN BIOSYNTHESIS Leonid Danilov, N. Utkina, T. Druzhinina, V. Torgov, V. Veselovsky Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia 29. BIVALENT SPERMINE-BASED NEUTRAL NEOGALACTOLIPIDS FOR MODULAR GENE DELIVERY SYSTEMS Michael A. Maslov,a E. A. Ivanova,a N. G. Morozova,a A. V. Filatov,b M. A. Zenkovab a Lomonosov Moscow State University of Fine Chemical Technologies, Moscow, Russia b Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk, Russia 30. SYNTHESIS OF P1-[11-(ANTHRACEN-9-YLMETHOXY)UNDECYL]-P2(α-D-GlcpNAc AND α-D-GalpNAc) DIPHOSPHATES AND STUDIES OF THEIR ACCEPTOR PROPERTIES IN THE ENZYMATIC REACTIONS CATALYZED BY D-RHAMNOSYLTRANSFERASE FROM Pseudomonas aeruginosa Natalia Utkina,a V. Torgov,a A. Vinnikova,a V. Veselovsky,a L. Danilov,a S. Wang,b I. Brockhausenb a N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow 119991, Russia b Queen׳s University, Kingston, Ontario, Canada 31. SYNTHESIS OF LIPID A ANALOGUES AS PROSPECTIVE ANTIINFLAMMATORY AGENTS Alessio Borio, P. Kosma, A. Zamyatina Department of Chemistry, University of Natural Resources and Life Sciences, Vienna, Austria 36 Eurocarb18 August 3, 2015 Poster Session 1 32. SYNTHESIS OF CHIMERIC LEWIS/ABH GLYCANS IN FORM OF NEOGLYCOLIPIDS Ivan M. Ryzhov,a E. Y. Korchagina,a I. S. Popova,a T. V. Tyrtysh,a G. V. Pazynina,a A. B. Tuzikov,a S. Henry,b N. V. Bovina a Laboratory of Carbohydrates, Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia b AUT, Auckland, New Zealand 33. SYNTHESIS OF LPS INNER CORE FRAGMENTS OF Acinetobacter haemolyticus Angelika Derler, P. Kosma Deptatment of Chemistry, University of Natural Resources and Life Sciences, Vienna, Austria 34. SEVERAL EXAMPLES OF -GALACTOSAMINYLATION IN LARGE-SCALE SYNTHESIS OF A TETRASACCHARIDE (TYPE 2) Tatiana V. Tyrtysh, E. Yu. Korchagina, N. V. Bovin Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia 35. CAPILLARY ELECTROPHORESIS FOR TOTAL GLYCOSAMINOGLYCAN ANALYSIS Ebru Uçaktürk,a C. Cai,b L. Li,b G. Li,b F. Zhang,b R. J. Linhardtb,c a Department of Analytical Chemistry, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey b Department of Chemistry and Chemical Biology, Rensselaer Polytechnic Institute, Troy, New York, USA c Department of Biomedical Engineering, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York, USA 36. OH PROJECTION: THE LATEST FRONTIER TO DEFINE GEOMETRY OF CARBOHYDRATES Clarissa Oliveira da Silva, L. G. Alves, R. R. Andrade Dep. de Química-ICE, Universidade Federal Rural do Rio de Janeiro, Seropédica, Rio de Janeiro, Brazil 37. ENORMOUSLY DIVERSE O-ANTIGEN MODIFICATIONS, THE UNDERLYING GENETIC MECHANISMS, AND EXTENSION OF THE SEROTYPING SCHEME OF Shigella flexneri Y. A. Knirel,a Q. Sun,b Sofya N. Senchenkova,a A. S. Shashkov,a J. Xub a N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia b National Institute for Communicable Disease Control and Prevention, China CDC, Changping, Beijing, China 37 Eurocarb18 August 3, 2015 Poster Session 1 38. STRUCTURES AND GENETICS OF THE O-ANTIGENS OF Enterobacter cloacae Andrei V. Filatov,a A. V. Perepelov,a A. S. Shashkov,a M. Wang,b L. Wang,b Y. A. Knirela a N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia b TEDA Institute of Biological Sciences and Biotechnology, Nankai University, TEDA, Tianjin, China 39. STRUCTURE AND GENETICS OF CAPSULAR POLYSACCHARIDES OF Acinetobacter baumannii, AN EMERGING NOSOCOMIAL PATHOGEN Sofya N. Senchenkova,a N. P. Arbatsky,a A. S. Shashkov,a O. A. Chizhov,a M. M. Shneider,b A. V. Popova,c,d K. A. Miroshnikov,b N. V. Volozhantsev,c Y. A. Knirela a N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia b M. M. Shemyakin & Y. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia c State Research Center for Applied Microbiology and Biotechnology, Obolensk, Moscow Region, Russia d Moscow Institute of Physics and Technology, Dolgoprudny, Moscow Region, Russia 40. ANHYDROUS TRIFLUOROACETIC ACID AS A NOVEL SOLVOLYTIC REAGENT FOR SELECTIVE CLEAVAGE OF GLYCOSIDIC LINKAGES Andrei V. Perepelov, A. V. Filatov, A. S. Shashkov, Y. A. Knirel N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia 41. CLEAVAGE OF THE O-ANTIGEN OF Escherichia coli O157 BY A RECOMBINANT TAILSPIKE PROTEIN OF BACTERIOPHAGE CBA120 Nikolay P. Arbatsky,a M. M. Schneider,b S. A. Buth,c Y. A. Knirel,a K. A. Miroshnikov,b P. Leimanc a N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia b M. M. Shemyakin & Y. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia c École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland 42. STRUCTURE OF THE O-POLYSACCHARIDE OF Riemerella anatipestifer CH-2 (SEROTYPE 2) Olesya V. Naumenko,a,b D. Zhu,c,d E. A. Levina,a,b H. Luo,c,d A. S. Shashkov,a L. Wang,c,d A. V. Perepelov,a M. Wang,d,e Y. A. Knirel,a A. Chengc,d a N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia b Higher Chemical College, Russian Academy of Sciences, Moscow, Russia c Research Center of Avian Diseases, College of Veterinary Medicine of Sichuan Agricultural University, Chengdu, P. R. China d Key Laboratory of Animal Disease and Human Health of Sichuan Province, Chengdu, P. R. China e Institute of Preventive Veterinary Medicine of Sichuan Agricultural University, Chengdu, P. R. China 38 Eurocarb18 August 3, 2015 Poster Session 1 43. STRUCTURAL AND GENETIC CHARACTERISATION OF THE O-ANTIGENS OF TWO NON-TYPABLE STRAINS OF Escherichia coli, G5413 AND G5287, CANDIDATES FOR NEW E. coli O-SEROGROUPS Anna M. Shpirt,a B. Liu,b A. S. Shashkov,a L. Wang,b Y. A. Knirela a N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia b TEDA Institute of Biological Sciences and Biotechnology, Nankai University, Tianjin, China 44. NEW STRUCTURE OF THE O-POLYSACCHARIDE OF Proteus mirabilis Bprz 86 Evgeniya A. Levina,a,b O. V. Naumenko,a,b O. G. Ovchinnikova,a D. Drzewiecka,c A. S. Shashkov,a Y. A. Knirela a N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia b Higher Chemical College, Russian Academy of Sciences, Moscow, Russia c Department of General Microbiology, University of Lodz, Lodz, Poland 45. SEROLOGICAL CLASSIFICATION OF RHIZOBACTERIA Azospirillum AND STRUCTURE OF THEIR O ANTIGENS Yuliya P. Fedonenko,a E. N. Sigida,a S. A. Konnova,b E. L. Zdorovenko,c V. V. Ignatova a Institute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences, Saratov, Russia b Chernyshevsky Saratov State University, Saratov, Russia c Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia 46. NEW STRUCTURES OF KDN-TEICHULOSONIC ACIDS FROM THE CELL WALLS OF ACTINOBACTERIA Galina Streshinskaya,a A. Shashkov,b E. Tul’skaya,a N. Potekhina,a S. Senchenkova,b A. Dmitrenok,b L. Baryshnikovac a School of Biology, M. V. Lomonosov Moscow State University, Moscow, Russia b N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia c All-Russian Collection of Microorganisms (VKM), G. K. Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, Pushchino, Moscow Region, Russia 47. EFFECT OF CULTIVATION CONDITIONS ON THE COMPOSITION AND STRUCTURE OF Azospirillum SURFACE GLYCOPOLYMERS S. S. Yevstigneyeva,a Y. N. Nekrasova,a M. V. Kanevsky,b E. N. Sigida,a Y. P. Fedonenko,a Svetlana A. Konnova,b V. V. Ignatova a Institute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences, Saratov, Russia b Chernyshevsky Saratov State University, Saratov, Russia 39 Eurocarb18 August 3, 2015 Poster Session 1 48. PYRUVYLATED CELL WALL GLYCOPOLYMERS OF TWO STRAINS OF Promicromonospora citrea Elena Tul’skaya,a A. Shashkov,b G. Streshinskaya,a N. Potekhina,a S. Senchenkova,b A. Dmitrenok,b O. Bueva,c a School of Biology, M. V. Lomonosov Moscow State University, Moscow, Russia b N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia c All-Russian Collection of Microorganisms (VKM), G. K. Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, Pushchino, Moscow Region, Russia 49. TWO FACES OF -1,6-GLUCAN FROM Saccharomyces cerevisiae BIM Y-195 Galina I. Novik,a E. L. Zdorovenko,b K. I. Mikhailopulo,c E. P. Kiselevac a Institute of Microbiology, National Academy of Sciences of Belarus, Minsk, Republic of Belarus b N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia c Institute of Bioorganic Сhemistry, National Academy of Sciences of Belarus, Minsk, Republic of Belarus 50. STRUCTURE DETERMINATION OF THE NEUTRAL EXOPOLYSACCHARIDE PRODUCED BY Lactobacillus delbrueckii SUBSP. bulgaricus OLL1073R-1 Marie-Rose Van Calsteren,a F. Gagnon,a H. Sabik,a J. Nishimura,b,c S. Makinod a Food Research and Development Centre, Agriculture and Agri Food Canada, Saint Hyacinthe (QC), Canada b Laboratory of Animal Products Chemistry, Graduate School of Agricultural Science, Tohoku University, Aobaku, Sendai, Japan c Present address: Department of Biotechnology and Environmental Engineering, Faculty of Engineering, Hachinohe Institute of Technology, Myo Hachinohe, Aomori, Japan d Lactic Acid Bacteria Research Department, Food Science Research Laboratories, Meiji Co., Ltd., Odawara, Kanagawa, Japan 51. CROSS-ACTIVITY OF SERUM ANTIBODIES FROM MICE IMMUNIZED WITH APYROGENIC MODIFIED LIPOPOLYSACCHARIDE OF Shigella flexneri 2a TO OTHER SEROGROUPS AND SEROTYPES OF Shigella flexneri Vladimir A. Ledov, P. G. Aparin National Research Center Institute of Immunology, Federal Medical-Biological Agency (FMBA of Russia), Moscow, Russia 40 Eurocarb18 August 3, 2015 Poster Session 1 52. EXPLAINING THE SEROLOGICAL BEHAVIOR OF Streptococcus suis SEROTYPES 1 AND 1/2 FROM THEIR CAPSULAR POLYSACCHARIDE STRUCTURE AND BIOSYNTHESIS Marie-Rose Van Calsteren,a,b G. Goyette-Desjardins,b,c F. Gagnon,a A. Brousse,a C. Soudier,a M. Okura,d D. Takamatsu,d,e M. Gottschalk,b,c M. Segurab,c a Food Research and Development Centre, Agriculture and Agri-Food Canada, Saint-Hyacinthe (QC), Canada b Centre de recherche en infectiologie porcine et avicole (CRIPA) and cGroupe de recherche sur les maladies infectieuses du porc (GREMIP), Faculté de médecine vétérinaire, Université de Montréal, Saint-Hyacinthe (QC), Canada d Research Team for Bacterial/Parasitic Diseases, National Institute of Animal Health, National Agriculture and Food Research Organization, Tsukuba, Ibaraki, Japan e United Graduate School of Veterinary Sciences, Gifu University, Gifu, Japan 53. O-ANTIGEN GLUCOSYLATION IN A HETEROLOGOUS ABC TRANSPORTER DEPENDENT SYNTHESIS SYSTEM Olga G. Ovchinnikova, E. Mann, J. D. King, C. Whitfield Department of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, Canada 54. CELL WALL POLYSACCHARIDES FROM WOODY BAMBOO SHOOTS OF Guadua chacoensis AND Phyllostachys aurea Marina Ciancia,a,b V. M. Zelaya,a A. S. Vega,c P. V. Fernándeza,b a Cátedra de Química de Biomoléculas, Departamento de Biología Aplicada y Alimentos, Facultad de Agronomía, Universidad de Buenos Aires, Buenos Aires, Argentina b CIHIDECAR-CONICET, Departamento de Química Orgánica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, Buenos Aires, Argentina c Cátedra de Botánica General, Departamento de Recursos Naturales y Ambiente, Facultad de Agronomía, Universidad de Buenos Aires, Buenos Aires, Argentina 55. O-POLYSACCHARIDE OF Escherichia coli 4S AND ITS ROLE IN THE INTERACTION WITH BACTERIOPHAGES N. S. Prokhorov,a Evelina L. Zdorovenko,b A. K. Golomidova,a P. Leiman,c C. Riccio,c E. S. Kostryukova,d A. K. Larin,d Y. A. Knirel,b A. V. Letarova a S. N. Winogradsky Institute of Microbiology, Russian Academy of Sciences, Moscow, Russia b N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia c École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland d Institute of Physical and Chemical Medicine, Federal Medical and Biological Agency, Moscow, Russia 41 Eurocarb18 August 3, 2015 Poster Session 1 56. BACTERIOPHAGE TAILSPIKES AS CARBOHYDRATE BINDING PROTEINS IN EXPERIMENTAL AND COMPUTATIONAL APPROACHES TO ANALYZE BINDING AFFINITIES R. Sonja Kunstmann,a N. K. Broeker,a Y. Kang,b U. Gohlke,c U. Heinemann,c, d R. Lipowsky,b R. Seckler,a M. Santer,b S. Barbirza a Physical Biochemistry, University of Potsdam, Potsdam, Germany b Theory and Bio-Systems, Max Planck Institute of Colloids and Interfaces, Potsdam, Germany c Max-Delbrück-Centre for Molecular Medicine, Macromolecular Structure and Interaction, Berlin, Germany d Institute for Chemistry and Biochemistry, Free University Berlin, Berlin, Germany. 57. MULTIFACETED LECTIN AND GLYCOSIDASE LIGANDS Carmen Ortiz Mellet,a E. M. Sánchez Fernández,a C. D. Navo,b R. GonçalvesPereira,a F. Corzana,b G. Jiménez-Osés,c,d A. Avenoza,b J. H. Busto,b J. M. García Fernández,e J. M. Peregrinab a Universidad de Sevilla, Sevilla, Spain b Universidad de La Rioja, Logroño, Spain c University of California, Los Angeles, California, USA d BIFI-IQFR, CSIC - Universidad de Zaragoza, Zaragoza, Spain e IIQ, CSIC - Universidad de Sevilla, Sevilla, Spain 58. STUDY OF INTERACTIONS OF MANNAN ISOLATED FROM Candida dubliniensis WITH CONCANAVALIN A AND RABBIT ANTISERA A. Šedivá, I. Medovarská, I. Slaninková, P. Gemeiner, S. Bystrický, Jaroslav Katrlík Institute of Chemistry, Slovak Academy of Sciences, Bratislava, Slovakia 59. INTERACTION STUDIES BETWEEN CARBOHYDRATE RESIDUES OF BACTERIAL LIPOPOLYSACCHARIDES (LPS) AND LYSOZYMES R. Zhang,a,b T. Eckert,c Vadim B. Krylov,d R. Schauer,e A. J. Scheidig,b A. Bhunia,f M. Abdulaziz Enani,g Z. Gazova,h N. E. Nifantiev,d H.-C. Sieberta a RI-B-NT Research Institute of Bioinformatics and Nanotechnology, Franziusallee 177, 24148 Kiel, Germany b Zoologisches Institut – Strukturbiologie, Zentrum für Biochemie und Molekularbiologie, Christian-Albrechts-Universität, Kiel, Germany c Klinik für Geburtshilfe, Gynäkologie und Andrologie der Groß und Kleintiere mit Tierärztlicher Ambulanz, Fachbereich Veterinärmedizin, Justus-Liebig-Universität Gießen, Gießen, Germany d Laboratory of Glycoconjugate Chemistry, Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia e Biochemisches Institut, Universität Kiel, Kiel, Germany f Biomolecular NMR and Drug Design Laboratory, Department of Biophysics, Bose Institute, Kolkata, India g Infectious Diseases Division, Department of Medicine, King Fahad Medical City, Riyadh, Kingdom of Saudi Arabia h Department of Biophysics Institute of Experimental Physics, Slovak Academy of Sciences, Kosice, Slovakia. 60. TOWARDS SMALL BIOACTIVE MOLECULE GLYCOSYLATION Malte Timm,a S. F. Seibert,b M. Krohn,b J. Seibela a Institute of Organic Chemistry, University of Würzburg, Würzburg, Germany b B.R.A.I.N. AG, Zwingenberg, Germany 42 Eurocarb18 August 3, 2015 Poster Session 1 61. ROLE OF GLYCOSYLATION IN SECRETION AND STABILITY OF MICROMYCETES -GALACTOSIDASES Liudmila D. Varbanets, N. V. Borzova, O. V. Gudzenko Danylo Zabolotny Institute of Microbiology and Virology National Academy of Science of Ukraine, Ukraine, Kyiv 62. UNCONVENTIONAL THERAPEUTIC STRATEGY FOR THE TREATMENT OF Trichomonas vaginalis INFECTIONS WITHOUT DRUG ADDITION B. Pradines,a,b C. Bories,b C. Vauthier,a T. Grisin,a G. Ponchel,a P. M. Loiseau,b Kawthar Bouchemala a Institut Galien Paris Sud, UMR CNRS 8612 and bBioCis, UMR CNRS 8076, Antiparasitic Chemotherapy, School of Pharmacy, University Paris Sud, ChâtenayMalabry, France 63. EXPRESSION OF FUNCTIONAL HUMAN SIALYLTRANSFERASES IN Escherichia coli FOR THE SYNTHESIS OF Α-2,3- AND Α-2,6-SIALYL-OLIGOSACCHARIDES Maria E. Ortiz-Soto, J. Seibel Institute of Organic Chemistry, University of Würzburg, Würzburg, Germany 64. CHITOSAN ASSEMBLIES SYNERGISTICALLY ENHANCE THE ANTIFUNGAL ACTIVITY OF AMPHOTERICIN B AGAINST Candida albicans T. Grisin,a C. Bories,b P. M. Loiseau,b J.-M. Mallet,c Kawthar Bouchemala a Institut Galien Paris Sud, UMR CNRS 8612 and bBioCis, UMR CNRS 8076, Antiparasitic Chemotherapy, School of Pharmacy, University Paris Sud, ChâtenayMalabry, France c École Normale Supérieure-PSL Research University, Département de Chimie, Paris, France 43 Eurocarb18 August 4, 2015 Poster Session 2 TUESDAY, AUGUST 4, 2015 POSTER SESSION 2 Place de Paris 10:3011:30 SESSION 2A. Authors of posters with odd numbers stand by their posters. 16:0017:00 SESSION 2B. Authors of posters with even numbers stand by their posters. 65. SYNTHESIS TOWARDS BACTERIAL MIMETICS OF HIV-1 GP120 GLYCANS Nino Trattnig,a J. B. Farcet,a R. Pantophlet,b P. Kosmaa a Department of Chemistry, University of Natural Resources and Life Sciences, Vienna, Austria b Faculty of Health Sciences and Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, Canada 66. N-t-BUTANESULFINYL GLYCOSYLAMINES: SYNTHESIS AND EXPLOITATION FOR THE PREPARATION OF NOVEL GLYCOSIDE MIMICS IN THE IMINOSUGAR SERIES Chloe Cocaud,a C. Nicolas,a A. Bayle,b T. Poisson,b X. Pannecoucke,b O. R. Martina a ICOA, UMR-7311, University of Orléans and CNRS, Orléans, France b COBRA, UMR-6014, University of Rouen, INSA Rouen and CNRS, Mont Saint Aignan, France 67. CLICKABLE SACCHARIDES AND SACCHARIDE MIMETICS FOR TARGETING DENDRITIC CELLS Jens Langhanki, T. Opatz Institute of Organic Chemistry, University of Mainz, Mainz, Germany 68. PROGRAMMED SYNTHETIC GAG FRAGMENT-BASED DIMER MIMETICS AND CONJUGATES Robin A. Jeanneret,a C. E. Dalton,a D. R. Cummings,a J. Bella,a G. C. Jayson,b J. M. Gardinera a Manchester Institute of Biotechnology and School of Chemistry, The University of Manchester, Manchester, UK b Institute of Cancer Sciences, Christie Hospital and University of Manchester, Manchester, UK 69. BIOMIMETIC SYNTHESIS OF THE TUMOR-ASSOCIATED (2,3)-SIALYL T ANTIGEN AND ITS INCORPORATION INTO A MUC1-GLYCOPEPTIDE RESULTING IN AN ANTITUMOUR VACCINE Markus Glaffig,a N. Stergiou,b B. Palitzsch,a E. Schmitt,b H. Kunza a Institute of Organic Chemistry, University of Mainz, Germany b Institute of Immunology, University Medical Center of Mainz, Germany 70. A NOVEL FULLY SYNTHETIC GLYCOPEPTIDE VACCINE AGAINST TUMOR-ASSOCIATED MUCIN 1 ELICITS NOT ONLY SPECIFIC HUMORAL BUT STRONG CD8 T CELL RESPONSES Natascha Stergiou,a B. Palitzsch,b E. Schmitt,a H. Kunzb a Institute of Immunology, University Medical Center of Mainz, Germany b Institute of Organic Chemistry, Mainz, Germany 44 Eurocarb18 August 4, 2015 Poster Session 2 71. SYNTHETIC APPROACHES TOWARDS THE PREPARATION OF GALECTIN1 FLUORINATED LIGANDS Cecilia Romanò, S. Oscarson Centre for Synthesis and Chemical Biology, School of Chemistry and Chemical Biology, University College Dublin, Belfield, Dublin 4, Ireland 72. SYNTHESIS OF GLYCOCONJUGATED, WATER-SOLUBLE ZINC(II)PHTHALOCYANINES FOR THE USE IN PHOTODYNAMIC THERAPY Felix Bächle, M. Hanack, T. Ziegler Institute of Organic Chemistry, Eberhard Karls Universität Tübingen, Tübingen, Germany 73. SYNTHESIS OF SIALIC ACID AND β-GALACTOSIDE LIBRARIES: ESSENTIAL TOOLS IN STRUCTURE ACTIVITY RELATIONSHIP INVESTIGATIONS Austin McCabe, S. Oscarson UCD Centre for Synthesis and Chemical Biology, School of Chemistry and Chemical Biology, University College Dublin, Belfield, Dublin 4, Ireland 74. NEW AROMATIC & ALIPHATIC GLYCOCONJUGATES BUILDING BLOCKS FOR THE CONSTRUCTION OF COMBINATORIAL GLYCOPEPTIDE LIBRARIES Markus Nörrlinger, T. Ziegler Institute of Organic Chemistry, Department of Chemistry, University Tübingen, D-72076 Tübingen, Germany 75. NEW FAMILY OF AMPHIPHILIC ALKYL RHAMNOSIDES: SYNTHESIS, STRUCTURAL CHARACTERIZATION AND BIOLOGICAL ACTIVITY Z. Hricovíniová,a A. Medveďová,b L. Valík,b Miloš Hricovínia a Institute of Chemistry, Slovak Academy of Sciences, SK-845 38 Bratislava, Slovakia b Institute of Biochemistry, Nutrition and Health Protection, Slovak University of Technology, SK-812 37 Bratislava, Slovakia 76. SYNTHESIS OF NEW SUGAR-BASED OXAZOLINE LIGANDS J. Kraft, Markus Nörrlinger, T. Ziegler Institute of Organic Chemistry, University of Tübingen, Tübingen, Germany 77. A FACILE GLYCONANOPARTICLE FABRICATION METHOD THROUGH THE COMBINATION OF PFPA-PHOTOCHEMISTRY AND AZIDE-ALKYNE CLICK CHEMISTRY C. Shao,a X. Li,a Z. Pei,a H. Dong,b Yuxin Pei,a a College of Science, Northwest A&F University, Yangling, Shaanxi, China b School of Chemistry & Chemical Engineering, Huazhong University of Science & Technology, Wuhan, China 78. SYNTHESIS AND CHARACTERIZATION OF NEW BICYCLIC CARBONBRANCHED CARBOHYDRATE DERIVATIVES Daniel Borowski, M. Menzel, T. Ziegler Institute of Organic Chemistry, Eberhard Karls University Tübingen, Tübingen, Germany 45 Eurocarb18 August 4, 2015 Poster Session 2 79. SYNTHESIS OF HETERO-MULTIVALENT “SWEET SWITCHES” Christian Müller, T. K. Lindhorst Otto Diels Institute of Organic Chemistry, Christiana Albertina University of Kiel, Kiel, Germany 80. SELF-ASSEMBLING CATIONIC CLUSTERS FROM CYCLODEXTRIN AND TREHALOSE-BASED MACROCYCLES FOR EFFICIENT GENE DELIVERY Jose M. García Fernández,a L. Gallego-Yerga,b L. Blanco-Fernández,c K. Urbiola,c T. Carmona,d G. Marcelo,d J. Rodríguez-Lavado,b J. L. Jiménez Blanco,b J. M. Benito,a F. Mendicuti,d C. Tros de Ilarduya,c C. Ortiz Melletb a IIQ, CSIC - Universidad de Sevilla, Sevilla, Spain b Universidad de Sevilla, Sevilla, Spain c Universidad de Navarra, Pamplona, Spain d Universidad de Alcalá de Henares, Alcalá de Henares, Spain 81. SYNTHESIS OF AN ORTHORGONAL TRIVALENT CARBOHDRATE SCAFFOLD FOR THE PREPARATION OF AZOBENZENE GLYCOCLUSTERS Anne Müller, T. K. Lindhorst Christiana Albertina University of Kiel, Otto Diels Institute of Organic Chemistry, Kiel, Germany 82. PREPARATION OF GALECTIN-3 INHIBITORS TO QUESTION THE ROLE OF THIS LECTIN IN BIOLOGICAL PROCESSES Cyrille Grandjean,a J. Dion,a S. Dahbi,a N. Storozhylova,a C. Solleux,a S. Téletchéa,a C. Tellier,a P. Pigny,b P. Reboul,c F. Deshayes,d J. Magescas,d D. Delacour,d F. Poirierd a Unit Function & Protein Engineering UMR CNRS 6286, University of Sciences and Techniques, Nantes, France b UMR-S 1172 Inserm, Centre de Recherche Jean-Pierre Aubert, University of Lille, France c IMoPA,UMR CNRS7365, University of Lorraine, Nancy, France d Institut Jacques Monod, UMR CNRS 7592, Unibersity of Paris Diderot, France 83. A NEW GLYCOCALYX MODEL FOR GLYCOARRAYS: DESIGN OF A HETERO-GLYCOSYLATED SCAFFOLD WITH A CHIRAL FOCAL POINT Guillaume Despras, C. Müller, C. Fessele, T. K. Lindhorst Otto Diels Institute of Organic Chemistry, Christiana Albertina University of Kiel, Kiel, Germany 84. ARYL MANNOSIDES AS ANTAGONISTS FOR FimH IN HIGH- AND LOW-AFFINITY STATE Oliver Schwardt, S. Rabbani, D. Eris, P. Frei, J. Bezençon, S. Kleeb, B. Ernst Institute of Molecular Pharmacy, University of Basel, Basel, Switzerland 85. PROBING MAMMALIAN CELL-SURFACE LECTINS WITH GLYCANCONJUGATED NANOPARTICLES Injae Shin, G.-H. Kim, J. Pai, J. Y. Hyun Department of Chemistry, Yonsei University, Seoul, Korea 46 Eurocarb18 August 4, 2015 Poster Session 2 86. COMBINATORIAL SYNTHESIS OF HIGH-AFFINITY SIALIC ACID ANALOGS Ebbe Engholm, N. Stuhr-Hansen, M. Meldal, O. Blixt University of Copenhagen, Department of Chemistry, Copenhagen, Denmark 87. DUAL-MODAL FLUORESCENT MAGNETIC GLYCONANOPARTICLES TO PROBE Helicobacter pylori Ji Young Hyun, S.-H. Park, J. Pai, I. Shin Department of Chemistry, Yonsei University, Seoul, Korea 88. SYNTHESIS OF STARCH / POLY (ACRYLIC ACID) GRAFT COPOLYMER HYDROGEL AND ITS USE FOR REMOVAL OF CADMIUM ION FROM WASTEWATER Essam S. Abdel-Halim Chemistry Department, College of Science, King Saud University, Riyadh, Kingdom of Saudi Arabia 89. REMOVING UNWANTED CARBOHYDRATES BY SELECTIVE BIOCONVERSION WITH IMMOBILIZED YEASTS CELLS FOR THE PURIFICATION OF GALACTO-OLIGOSACCHARIDES Carla Aburto Gajardo, C. Guerrero, E. Araya, A. Herrera, L. Wilson, A. Illanes Biochemical Engineering School, Pontificia Universidad Católica de Valparaíso, Valparaíso, Chile 90. SYNTHESIS OF FUROSTANOL SAPONINS AND THEIR -GLUCOSIDASE INHIBITORY ACTIVITIES Peng Wang, B. Li, M. Li Key Laboratory of Marine Medicine, Ministry of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao, Shandong, China 91. PIEZOQUARTZ CARBOHYDRATE BIOSENSORS Elena Kalmykova Lipetsk State Technical University, Lipetsk, Russia University of Dodoma, Dodoma, Tanzania 92. PHOTO-REACTIVE SLIDE GLASS FOR GLYCAN ARRAY Shiro Komba Biomolecular Engineering Laboratory, National Food Research Institute, NARO, Tsukuba, Japan 93. REVERSE MICELLAR ENCAPSULATION OF D- AND L-ENANTIOMERS OF AROMATIC -AMINO ACIDS USING GLUCOSE BASED NON-IONIC GEMINI SURFACTANTS HAVING A LINEAR SPACER Lalit Sharma, N. Singh Shaheed Bhagat Singh State Technical Campus, Ferozepur, India 94. DESIGN OF VERSATILE SYNTHETIC PROBES FOR EFFICIENT SCREENING AND EVALUATION OF FERULOYL ESTERASE ACTIVITIES O. Gherbovet, F. Ferreira, J. Durand, M. Ragon, G. Hostyn, S. Bozonnet, Regis Fauré, M. J. O'Donohue Université de Toulouse, INSA, UPS, INP, LISBP, Toulouse, France INRA, UMR792, Ingénierie des Systèmes Biologiques et des Procédés, Toulouse, France CNRS, UMR5504, Toulouse, France 47 Eurocarb18 August 4, 2015 Poster Session 2 95. SYNTHESIS OF PSEUDO-SUGARS AS NEW glmS RIBOSWITCH ACTIVATORS Daniel Matzner, G. Mayer University of Bonn, LIMES Institute, Chemical Biology, Bonn, Germany 96. SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL C-ARYL GLUCOSIDES AS SGLT2 INHIBITORS Q. Yan, S. Ren, Y. Wang, Yingxia Li School of Pharmacy, Fudan University, Shanghai, China 97. SYNTHESIS AND ANALYSIS OF GUANOSINEDIPHOSPHATE-β-L-FUCOSE ANALOGUES AS POTENTIAL IRREVERSIBLE HUMAN FUCOSYLTRANSFERASE IX INHIBITORS Tomas Piernitzki,a M. Bärenfänger,a K. Seelhorst,b U. Hahn,b B. Meyer,a C. Meiera a Organic Chemistry, University Hamburg, Hamburg, Germany b Biochemistry, University Hamburg, Hamburg, Germany 98. ENHANCING ENZYME ACTIVITY WITH INHIBITORS Alen Sevšek, N. I. Martin, R. J. Pieters Department of Medicinal Chemistry and Chemical Biology, University of Utrecht, The Netherlands 99. COMPOSITIONAL AND STRUCTURAL ANALYSIS OF THE LIPOPOLYSACCHARIDE FROM THE ORAL BACTERIUM Selenomonas sputigena ATCC 35185 Cornelia Rath,a K. Duda,b O. Holst,b C. Schäffera a Department of NanoBiotechnology, NanoGlycobiology unit, Universität für Bodenkultur Wien, 1190 Vienna, Austria b Structural Biochemistry, Research Center Borstel, Leibniz-Center for Medicine and Biosciences, 23845 Borstel, Germany 100. STRUCTURAL HETEROGENEITY AND BIOLOGICAL ACTIVITY OF LIPID A ISOLATED FROM LIPOPOLYSACCHARIDE OF Niveispirillum irakense (FORMERLY Azospirillum irakense) KBC1 Vyacheslav S. Grinev,a A. K. Surkina,a Yu. P. Fedonenko,a E. N. Sigida,a S. A. Konnova,b V. V. Ignatova a Institute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences, Saratov, Russia b Chernyshevsky Saratov State University, Saratov, Russia 101. STRUCTURAL ELUCIDATION OF Lactobacillus buchneri CD034 S-LAYER ANCHOR Eva Smolar,a A. Hofinger-Horvath,b K. Duda,c O. Holst,c P. Kosma,b C. Schäffer,a P. Messnera a Department of NanoBiotechnology, NanoGlycobiology unit, Universität für Bodenkultur Wien, Vienna, Austria b Department of Chemistry, Universität für Bodenkultur Wien, Vienna, Austria c Structural Biochemistry, Research Center Borstel Leibnitz-Center for Medicine and Biosciences, Borstel, Germany 48 Eurocarb18 August 4, 2015 Poster Session 2 102. CHARACTERISATION OF Pantoea agglomerans LIPOPOLYSACCHARIDES Tatiana V. Bulygina, L. D. Varbanets Danylo Zabolotny Institute of Microbiology and Virology National Academy of Science of Ukraine, Ukraine, Kyiv 103. ACTIVATION OF THE MURINE TLR4 RECEPTOR BY LIPOPOLYSACCHARIDES WITH VARIOUS LIPID A VARIANTS Anna N. Kondakova,a K. V. Korneev,b,c N. P. Arbatsky,a A. Molinaro,e A. Palmigiano,f L. Sturiale,f D. Garozzo,f A. A. Kruglov,b,d M. S. Drutskaya,b S. A. Nedospasov,b,c,d Y. A. Knirel,a D. V. Kuprashb,c a Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia b Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia c Biological Faculty, Lomonosov Moscow State University, Moscow, Russia d Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia eUniversità di Napoli Federico II, Naples, Italy f CNR Institute for Polymers Composites and Biomaterials, Catania, Italy 104. POLYPHENOLIC GLYCOCONJUGATES WITH ANTICOAGULANT ACTIVITY ISOLATED FROM Sanguisorba officinalis L. Sebastian Balicki, I. Pawlaczyk-Graja, R. Gancarz Department of Organic and Pharmaceutical Technology, Faculty of Chemistry, Wrocław University of Technology, Wrocław, Poland Regional Specialist Hospital in Wrocław, Research and Development Centre, Wrocław, Poland 105. EXTRACTION AND CHARACTERIZATION OF GELLING PECTIN FROM Heracleum sosnowskyi MANDEN Olga Patova,a V. Golovchenko,a S. Ponomareva,a F. Vityazev,a A. Burkovb a Institute of Physiology, Komi Science Centre, The Urals Branch of the Russian Academy of Sciences, Syktyvkar, Russia b Federal Government-financed Educational Institution of Higher Professional Education “Vyatka State University”, Kirov, Russia 106. CARBOHYDRATE STRUCTURE DATABASE K. S. Egorova,a Roman R. Kapaev,b Y. A. Knirel,a Ph. V. Toukacha a Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia b Higher Chemical College of the Russian Academy of Sciences, Moscow, Russia 107. ADHESIVE PROPERTIS OF GELS OBTAINED FROM CALLUS CULTURES PECTIC POLYSACCHARIDES Anatoliy K. Melekhin, E. A.Günter Institute of Physiology, Komi Science Centre, Ural Branch of the Russian Academy of Sciences, Syktyvkar, Russia 49 Eurocarb18 August 4, 2015 Poster Session 2 108. MECHANICAL, THERMAL AND ACOUSTICAL CHARACTERIZATIONS OF A INSULATING BIO-COMPOSITE MATERIAL BUILD FROM CHITOSAN AND SUNFLOWER STALK AGGREGATES N. Mati-Baouche,a,b H. de Baynast,a,b C. J. S. Lopez-Mingo,c Cedric Delattre,a,b P. Leclaire,c A. Lebert,a,b P. Michauda,b a Université Clermont Auvergne, Université Blaise Pascal, Institut Pascal, ClermontFerrand, France b CNRS, UMR 6602, IP, Aubière, France c Université de Bourgogne, Laboratoire DRIVE, ISAT, Nevers, France 109. DEVELOPMENT OF METHOD FOR PREPARATION OF PECTIN HYDROGEL BEADS FOR DELIVERY OF BIOELEMENTS AND DRUGS IN THE UPPER GASTROINTESTINAL TRACT Mayya I. Perminova, O. A. Patova, E. V. Politova Institute of Physiology, Komi Science Centre, The Urals Branch of the Russian Academy of Sciences, Syktyvkar, Komi Republic, Russia 110. GLYCOSAMINOGLYCAN ANALYSIS OF HUMAN OSTEOARTHRITIS Pi-Hui Liang,a T.-S. Lin,a C.-C. Jiangb a School of Pharmacy, College of Medicine, National Taiwan University, Taipei 100, Taiwan bDepartment of Orthopedic Surgery, National Taiwan University Hospital, Taipei 100, Taiwan 111. THE SWELLING, MORPHOLOGY AND ADSORPTION CAPACITY OF CALCIUM PECTINATE GEL BEADS DERIVED FROM DIFFERENT PECTINs Sergey Popov,a M. Borisenkov,a P. Markov,a S. Litvinets,b O. Patova,a F. Vityazev,a L. Bakutova,a E. Martinson,b B. Ananchenko,b E. Durnevb a Institute of Physiology, Komi Science Centre, The Urals Branch of the Russian Academy of Sciences, Syktyvkar, Russia b Federal Government-financed Educational Institution of Higher Professional Education «Vyatka State University», Kirov, Russia 112. PECTIC POLYSACCHARIDES ARE THE KEY AGENTS OF PLANT “MUSCULES” Polina Mikshina,a A. Petrova,a B. Idiyatullin,a A. Shashkov,b D. Faizullin,a Y. Zuev,a T. Gorshkovaa a Kazan Institute of Biochemistry and Biophysics, Kazan Scientific Center, Russian Academy of Sciences, Kazan, Russia b Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia 113. THE EFFECT OF PECTIN ON COGNITIVE PERFORMANCE IN MICE Nikita Paderin, D. Khramova, S. Popov Institute of Physiology, Komi Science Centre, The Urals Branch of the Russian Academy of Sciences, Syktyvkar, Russia 114. CHARACTERIZATION OF EMULSIONS STABILIZED BY POLYSACCHARIDE FROM THE RED MICROALGA Porphyridium SP. Irit Dvir,a D. Meshulam,c,d A. Kravtsov,b U. Lesmes,c,d S. M. Aradb a Sapir Academic College, P.M. Hof Ashkelon, Israel b Dept. of Biotechnology Engineering, Ben-Gurion University of the Negev, BeerSheva, Israel c Dept. of Biotechnology and Food Engineering, Technion – IIT, Haifa, Israel d Russel Berrie Nanotechnology Institute, Technion- IIT, Haifa, Israel 50 Eurocarb18 August 4, 2015 Poster Session 2 115. STRUCTURE-FUNCTION STUDIES OF THE POLLEN-DERIVED GLYCOLIPID N. Gonzalez Roldan,a R. Engel,b H. Ewers,a D. Schwudke,c Katarzyna A. Dudab Divisions of aBiochemical Immunology,bStructural Biochemistry, Priority Area Asthma and Allergy, and cBioanalytical Chemistry, Priority Area Infections, Research Center Borstel, Airway Research Center North (ARCN), Member of the German Center for Lung Research, Borstel, Germany 116. TRITERPENE GLYCOSIDES OF Pulsatilla taurica STRUCTURES OF GLYCOSIDES FROM THE ROOTS OF Pulsatilla taurica G. P. Zaitsev,a V. Y. Chirva,b Alexander S. Shashkovc a National Institute of Vine and Wine 'Magarach', Russian Academy of Sciences, Yalta, Russia b V. I. Vernadskii Tavricheskii National Academy, Simferopol, Russia c N. D. Zelinskii Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia 117. CARBOHYDRATE BINDING MODULE ASSISTING GLYCOSYNTHASECATALYZED POLYMERIZATIONS V. Codera,a H. J. Gilbert,b M. Faijes,a Antoni Planasa a Laboratory of Biochemistry, Institut Químic de Sarrià, Universitat Ramon Llull, 08017 Barcelona, Spain b Institute for Cell and Molecular Biosciences, The Medical School, Newcastle University, Newcastle upon Tyne, UK 118. EXTL2: A KEY ENZYME FOR UNDERSTANDING GLYCOSIDIC BOND BIOSYNTHESIS WITH RETENTION OF CONFIGURATION Fernanda Mendoza,a H. Gómez,b J. M. Lluch,a L. Masgraua a Universitat Autònoma de Barcelona, Bellaterra, Spain b IRB, Barcelona, Spain 119. NEW INSIGHTS FOR ENZYME ENGINEERING OF FAMILY GH20 HEXOSAMINIDASES: LACTO-N-BIOSIDASE AS MODEL ENZYME C. Val-Cid, X. Biarnés, M. Faijes, Antoni Planas Laboratory of Biochemistry, Bioengineering Department, Institut Químic de Sarrià, Universitat Ramon Llull, Barcelona, Spain 120. COLOURIMETRIC AND FLUOROMETRIC SUBSTRATES FOR THE MEASUREMENT OF LICHENASE ACTIVITY Agnija Liadova, D. Mangan, V. McKie, B. McCleary Megazyme International, Bray Business Park, Bray, Co. Wicklow, Ireland 121. SPECIFICITY OF V. cholerae CHITIN OLIGOSACCHARIDE DEACETYLASE: PROBING THE “SUBSITE-CAPPING MODEL” IN DEFINING THE DEACETYLATION PATTERN Hugo Aragunde Pazos, M. Palomo, X. Biarnés, A. Planas Laboratory of Biochemistry, Institut Químic de Sarrià, Universitat Ramon Llull, Barcelona, Spain 122. ANTI-CARCINOMA EFFECT OF CHITOSAN-SILICA NANOPARTICLES ENCAPSULATED Antrodia camphorata POLYSACCHARIDES Zwe-Ling Kong, H.-P. Kuo, J.-S. Chang, K. L. B. Chang Department of Food Science, National Taiwan Ocean University, Keelung, Taiwan, R.O.C. 51 Eurocarb18 August 4, 2015 Poster Session 2 123. THE THERAPEUTIC POTENCY OF Echinacea GLYCOCONJUGATE Peter Capek,a M. Šutovská,b I. Kazimierová,b L. Pappová,b M. Jošková,b M. Matulová,a S. Fraňová,b I. Pawlaczyk,c R. Gancarzc a Institute of Chemistry, Center for Glycomics, Slovak Academy of Sciences, Bratislava, Slovakia b Department of Pharmacology, Jessenius Faculty of Medicine, Martin, Slovakia c Division of Organic and Pharmaceutical Technology, Wrocław University of Technology, Poland 124. THE PROTECTIVE EFFECTS OF CHITOSAN-ENCAPSULATED CURCUMIN ON TYPE 1 DIABETES-INDUCED HEART AND KIDNEY DAMAGE Hsiang-Ping Kuo,a Y.-L. Yan,a H.-I Yeh,b Zwe-Ling Konga* a Department of Food Science, National Taiwan Ocean University, Keelung, Taiwan, R.O.C. bDepartment of Medicine, Mackay Medical College, Taipei, Taiwan, R.O.C. 125. TOWARDS CATALYTIC ANTIBIOTICS Boris Smolkin, A. Vilensky, M. Shavit, E. Shulman, T. Baasov Schulich Faculty of Chemistry, Technion-Israel Institute of Technology, Haifa, Israel 126. 1,3,4-THIADIAZINE DERIVATIVES PROTEIN GLYCATION BLOCKERS FOR EXPERIMENTAL DIABETES MELLITUS CORRECTION Viktor V. Emelyanov,a E. A. Savateeva,a L. P. Sidorova,a T. A. Tseitler,a T. S. Bulavintseva,b I. F. Gette,b I. G. Danilova,b N. E. Maksimova,a N. N. Mochulskaya,a O. N. Chupakhin,a V. A. Chereshnevb a Federal State Autonomous Educational Institution of Higher Professional Education “Ural Federal University named after the first President of Russia B. N. Yeltsin”, Ekaterinburg, Russia b Institute of Immunology and Physiology, Ural Branch of the Russian Academy of Sciences, Ekaterinburg, Russia 127. RIBOSOME TARGETING ANTIBIOTICS AS SCAFFOLDS FOR NOVEL BACTERIAL MEMBRANE DISRUPTORS Ido M. Herzog, Y. Berkov-Zrihan, R. I. Benhamou, K. B. Steinbuch, M. Feldman, M. Fridman Organic Chemistry, Tel Aviv University, Tel-Aviv, Israel 128. ANTI-GLYCAN ANTIBODIES AS UNLIMITED RESERVOIR OF BIOMARKERS FOR CLINICAL DIAGNOSTICS Margaret E. Huflejt,a M. I. Vuskovicb a University of Warmia and Mazury, Faculty of Medical Sciences, Olsztyn, Poland b Department of Computer Science, College of Sciences, San Diego State University, San Diego, California, USA 52