AAPM Workshop Sept 2014 - American Academy of Pain Management
Transcription
AAPM Workshop Sept 2014 - American Academy of Pain Management
34. Worlds Unite: Treating Pain with Manual Medicine, Acupuncture, and Nutraceutical/ Herbal Medicine AAPM CONFERENCE WORKSHOP Sunday, September 21, 2014 • 8:00 am - 12:00 pm Presented by: Jay Sandweiss, D.O., C-NMM/OMM, F.A.A.M.A. 417 S. Fourth Ave. Ann Arbor, MI 48104 USA email: dr [email protected] website: www.doctorjaysandweiss.com Fax: (734) 668-6529 Integrating Manual Medicine and Nutritional Therapy with Acupuncture Dear Friends and Colleagues… It is always a distinct honor and pleasure to present workshops. As many of you know, I have been treating patients for over thirty years using a variety of modalities, including both complementary/ alternative therapies and conventional “standard of care” medicine. Buzz words like “evidence-based” and “standard of care” have undergone their own evolution in the past three decades. As a medical student, I was chastised for asking questions about the use of folic acid for the prevention of neural tube defects, magnesium for certain arrhythmias and migraine, fish oil for autoimmune disease and cardiovascular health, and the existence of Helicobacter Pylori(which my course instructor dismissed as “junk science” proposed by a misguided quack Australian). We laugh now as these examples have been integrated into mainstream medicine, but we must not forget that for better or worse, medical science is a very conservative, skeptical, critical entity that often dismisses truth with unfortunate consequences only to embrace these same facts later Jay Sandweiss, D.O., F.A.A.M.A. on down the road. Students of medical history are often appalled by what was the“standard of care” in those past times. Ridiculing and punishing handwashing with soap, femur amputations for the treatment of pernicious anemia, and dismissing “stocking-glove” paresthesias and carpal tunnel syndrome as psychiatric illnesses or malingering were all part of a long-established history of blaming the patient whenever possible and punishing those that threatened the reigning paradigm. As acupuncturists, we have seen a growing acceptance and demand from the public at large to provide our services. “Evidencebased” studies have slowly infiltrated the mainstream medical establishment to the point where acupuncture is often included as a viable intervention for numerous conditions. Similar patterns of change have occurred in the fields of manual medicine and nutritional therapy. The burden of “evidence-based” studies helps prevent dubious therapies from being accepted but also limits many legitimate treatments because of the onerous time/money constraints placed on the investigators. This is particularly true in the field of nutritional therapy where money is not readily available unless the payoff is a drug patent for the pharmaceutical companies. Ironically, many drug companies are, indeed, trying to capitalize on the works of nutritional pioneers by patenting a slight variant of a readily available nutritional product. Prescription fish oil, time-released niacin, vitamin B-12/Folate and a recently approved strontium-hybrid are but a few examples. Fortunately, several of the top nutraceutical companies are sponsoring clinical trials with their products at major research centers around the world. My knowledge of nutritionally based therapies represents a conflation of influences from many great teachers and innovators. A list of resources is included at the end of this introductory essay. My early teachers were Drs. George Goodheart Jr. and Walter Schmitt, who, along 1 with Harry Eidenier Jr. PhD, introduced me to the late and great genius, Royal Lee, DDS (the founder of Standard Process Laboratories. To this day, Dr. Lee’s work offers endless clinical pearls for effective patient care. Another huge leap of knowledge occurred studying the works of Jeffrey Bland, PhD. His seminars and publications are masterpieces that weave physiology, nutritional biochemistry, and clinical medicine into a vibrant working model. Many physicians have been transformed by courses offered by the Institute for Functional Medicine that teaches much of Dr. Bland’s life work. At the same time, Jonathan Wright, M.D. and Alan Gaby, M.D. were writing books and offering week-long courses to physicians. Their courses included applied nutritional therapies for almost every medical sub-specialty. After attending their course at the Omega Institute in 1988, I became convinced that medical nutrition was destined to become an integral part of mainstream medicine. Melvyn Werbach, M.D from UCLA came along with his wonderful Third Line Press publications that documented the use of dietary, nutritional, and herbal interventions for nearly every medical condition. Finally, Kirk Hamilton P.A. offered comprehensive reporting on research in the field of medical nutrition with his Clinical Pearls services. My apologies to all the many other great contributors, leaders, and pioneers whose names have not been included in this brief presentation. This workshop pertains to the integration of nutritional medicine and manual medicine with acupuncture. As medical acupuncturists we appreciate those interventions that enhance a healthy physiology and homeostasis. Current theories about acupuncture propose mechanisms that involve cellular molecular biology in its varied forms including: neurotransmitters, cellular messengers, immune cells and modulators, endogenous opioids and cannabinoids, and numerous other components of immunology, neurology, and metabolism. Nutritional medicine shares many similar characteristics. It seems reasonable to postulate that acupuncture interventions and nutritional interventions are capable of achieving similar effects under certain circumstances and an enhanced synergistic result in yet others. Often a pattern diagnosis in Chinese Medicine such as: Damp Heat in the Lower Jiao may represent in Western physiologic terms: intestinal dysbiosis involving an imbalanced microbial population in the bowel with overgrowth of candida albicans, the presence of parasites, and a deficiency of normal probiotic flora resulting in non-specific colitis or irritable bowel syndrome. An acupuncturist may choose to treat specific points that influence Damp Heat in the meridians: Spleen/Stomach, Large Intestine, Liver and Gall Bladder. Herbal formulas might be employed as well to resolve this issue. A functional medicine practitioner may order sophisticated stool studies, blood tests, and other tests before implementing a focused nutraceutical/pharmaceutical plan to resolve the abnormalities that appear in these investigations. Probiotics, prebiotics, antifungals, antimicrobials and nutrients that help heal and restore normal mucosal integrity may be utilized. Following treatment there will be a noticeable change in pulse and tongue findings from a Chinese Medicine standpoint in addition to the obvious clinical improvements. The question frequently arises as to whether or not acupuncture is necessary or sufficient to resolve these types of clinical disorders. During my internship year in medical school, I was completely cured by one acupuncture treatment for a refractory case of ulcerative proctitis that was confirmed by tissue biopsy and unresponsive to steroids. My physician friend, just back from China, diagnosed a severe Damp Heat invasion of my Lower Jiao by history, tongue and pulse diagnosis. This ”acupuncture healing” profoundly affected my life and viewpoint about illness and treatment. Nutritional modalities were not involved nor were manual treatments. 2 In my experience, acupuncture enhances the therapeutic effects of other modalities such as manual medicine or nutritional/pharmaceutical interventions. As physicians we appreciate the seriousness of pneumonia and will often prescribe an appropriate antibiotic. As medical acupuncturists, we would want to treat the Lung meridian and any additional corresponding meridian disturbances that were present during the illness and after the pneumonia had resolved. Furthermore, as healers we would seek out the inherent weaknesses or vulnerabilities that allowed our patient to acquire pneumonia in the first place. Acupuncture, nutritional medicine, and manual medicine can be pro-active and preventive in addition to being treatment responses for medical conditions. They are interventions that promote healing and homeostasis in addition to attacking pathology and dysfunction. As an integrative medicine physician, I am frequently treating patients with multiple interventions simultaneously. It is not unusual for these patients to receive nutritional/herbal therapies, dietary manipulations, manual therapies, and acupuncture in their total treatment plans. Identifying the specific curative factor or factors is therefore rather difficult. Each therapeutic input is intended to address or resolve specific aspects of the troubling condition. Some refer to the “combination- lock theory “ of healing wherein all the numbers (factors) must be known and the specific sequence is needed to unlock the lock (heal the condition). A brief example might be useful here. Suppose the patient has chronic asthma as their chief complaint and is currently not facing an acute life-threatening crisis. In addition to, or as an alternative to the typically prescribed medications such as Albuterol, Flovent, Singulair, Zyrtec , etc. one could prescribe a food elimination diet, nutritional supplements such as: vitamin B-12, vitamin C, magnesium, n-acetylcysteine, and quercitin to name just a few. Acupuncture needles could be administered based on the specific etiology imbalances discovered during pulse, tongue, and history diagnostics. Herbal formulas could be added to support and enhance the acupuncture effect. Manual medicine techniques could be utilized to remove mechanical restrictions in the diaphragm, cranium and axial skeleton. Lymphatic drainage and respiratorycirculatory techniques could be used as well. Mind-body therapies could be taught to reduce “stress” and control triggers from a mental-emotional origin. We can take advantage of the many readily available diagnostic tests for evaluating : nutritional deficiencies,toxicities, hormonal and metabolic disorders, food/chemical allergies and sensitivities, and bowel flora disturbances. Numerous studies have pointed out that nutritional deficiencies are common and often go unrecognized in our elderly population. As our “life energies” or “Jing” wanes with age there are often corresponding deficiencies seen with nutrients and hormones that if treated can markedly improve quality of life parameters. I hope you will find useful, information in this presentation that can benefit your patients, your families and yourselves. Applied nutritional therapy is wonderfully synergistic with medical acupuncture. While you treat a Liver problem from an acupuncture perspective with needles, you can simultaneously identify specific dietary and nutraceutical interventions by history, examination, and diagnostic testing. One can also treat the liver organ itself with viscreal manipulation. 3 TRAUMA : AN INTEGRATIVE MODEL FOR DIAGNOSIS AND TREATMENT internally causing a tissue reaction. Pain is the resultant which has varying degrees of intensity and effective interpretation with numerous avenues of transmission.” This lecture introduces a variety of treatment principles and modalities for patients who have suffered trauma in their past and are unable to move forward in their recovery. This presentation will not address the management of serious acute trauma that requires emergency interventions or acute hospital care. Rather, we will discuss approaches that can be utilized after the patient is medically stable but is “stuck” and unhappy with their current state of recovery. We often encounter these patients who have been told: “You’ll have to learn to live with it” (for the remainder of their lives). Be it chronic pain, loss of function, loss of motion, depression, or other sequelae to by traditional mainstream medicine. As acupuncturists we are quite familiar with these truths and most of us have already helped numerous patients with needles, moxa, and/or herbs. This session is meant to add to that growing list of possible complementary and alternative approaches for healing past trauma. THE “LIST” Osteopathic Manipulative Medicine: Cranial Osteopathy, Visceral Manipulation, StrainCounterstrain, Myofascial Release, Functional Release, Muscle Energy Technique, High Velocity Thrust, Facilitated Position Release, Balanced Ligamentous Tension, Percussion Hammer Special Attention to: Breathing( 3 Diaphragms), Visceral Mobility and Motility disorders, Sacrum-Coccyx(Holds fear/insecurity), Dural strains, Cranial/TMJ dysfunctions (often unexamined), Greenman’s “Dirty Half-dozen” (non-neutral facet joint restrictions, symphysis pubis shears, sacral posterior torsion or nutation, hip bone shear, short-leg/pelvic tilt syndrome, and muscle imbalance of the trunk and extremities), Nerve Restrictions, “Energy Sinks” (Robert Fulford’s Concept that is treated with the Percussion Vibrator) Chiropractic: Applied Kinesiology (Injury Recall Technique, Emotional Neurovascular Holding Points), Sacro-Occipital Technique (Suture Releases), Neuro-Emotional Technique Homeopathy: Arnica, Hypericum, Symphytum, Natrum Sulphuricum, Ruta Graveolens Bach Flower/ Other Flower Essences: Star of Bethlehem, Rescue Remedy, Revive All (FlorAlive Remedies) Aroma Therapy: Spruce, Rose, Lavender EMDR (Eye Movement Desensitization and Reprocessing): Psychotherapy Tool Redcord: A Revolutionary Rehab Device Prolotherapy: For hypermobilty unresponsive to other modalities or strengthening Nutritional/Metabolic: Evaluation of: Nutritional status (intracellular vs. other), Endocrine balance (blood, urine, saliva), Toxicity (hair, blood, urine, feces), Food and chemical Dysbiosis/”Leaky gut syndrome” (Comprehensive Stool Analysis), Immune panels with other traditional laboratory and diagnostic studies. Hypnotherapy, Biofeedback, Neurofeedback et al: Brain, behavior, and psyche Bioenergetics and other Mind-Body oriented therapies: Somato-emotional therapies 4 Rolfing, Hellerwork, Soma Bodywork, Anatomy Trains: Core patterns Magnets, Crystals, Lasers, and other energy transfer devices: Energy fields Shamanic Healing and other forms of “Soul Retrieval” Chinese Medicine: Seven Dragons, Chakra Acupuncture, Yintang, Shao Yin- Jue Yin groundingreleasing points: H-7, PC-6, LR-3, K-3, K-25, 26, 27, CV-17 Treat the “scattered” or “suspended” Qi, treat the loss of Heart Qi, Heart pulse is Fine and Tight, Complexion is bright-white or bluish tinged forehead. Pulse is rapid, short, shaped like a bean, vibrating Eyes may be dull without glitter** (from Giovanni Maciocia) As an osteopathic physician I have been greatly influenced by my teachers, mentors, and the past masters of my profession. To better understand the osteopathic philosophy and treatment approaches to trauma, I can highly recommend the writings and methods of: Andrew Taylor Still M.D./D.O., Rollin Becker D.O., Robert Fulford D.O., William Johnston D.O., Viola Frymann D.O, Myron Beal D.O., William Sutherland D.O., Fred Mitchell Jr. D.O., Lawrence Jones D.O., Anne Wales D.O., Irwin Korr Ph.D., Philip Greenman D.O., Robert Ward D.O., Anthony Chila D.O., Edward Stiles D.O., John Upledger D.O. and Jean-Pierre Barral D.O. This is a partial list but certainly representative of the rich and prolific tradition of osteopathic healers and educators. My first mentor, George Goodheart Jr., D.C., developed a unique system of diagnosis and treatment using manual muscle testing. His system, Applied Kinesiology, has been in a state of continual evolution for over 60 years. A central theme runs through his work known as the “Triad of Health”. This concept proposes that there is a continuous interaction between structure, chemistry, and emotional/energetic facets. When a patient presents with posttraumatic pain, there will undoubtedly be multiple somatic dysfunctions present. A careful history and thorough examination usually reveals biochemical and emotional- energetic problems as well. Food allergies, chemical sensitivities, toxicities, nutritional deficiencies, endocrine disturbances and subtle disorders of metabolism such as mitochondrial dysfunction are more common than one might imagine. “Post-Traumatic Stress Disorder” with its myriad of manifestations: Depression, Anxiety, OCD, ADHD, Paranoia, Phobias, Insomnia, Somatic Disorders, and Sexual Dysfunction, (just to name a few) is also quite common. Perhaps a case example might illustrate the application of this “Triad of Health” paradigm. A 45 year old white female has had three years of pain in the cervical, mid-thoracic and lower back regions following a whiplash injury. Additionally, she complains of retro-orbital and temporal headaches, jaw tension with “clicking and popping,” insomnia, fatigue, depression, anxiety, irritable bowel syndrome, irregular periods, right carpal tunnel syndrome, left patella pain, and “foggy, dull thinking.” All of these complaints began after the accident. She was stopped at a red light and was rear-ended at approximately 35 mph. She hit her head on the driver’s window, hit her knee cap into the dashboard, and felt extreme strain to her wrist during the accident. A month after the accident she developed a thyroid nodule with goiter and became hyperthyroid requiring Tapazole medication. Patients with these scenarios are often treated as if their entire whiplash injury is strictly limited to their musculoskeletal system. Medications, injections, physical therapy, chiropractic, massage and other musculoskeletal modalities are often employed. The lucky patients recover with those interventions alone. Some are not so lucky. 5 This patient requires deeper attention to the specific disruptions of her structure, chemistry, and energetic psychology. Osteopathic examination reveals: cranial somatic dysfunctions involving a petro-jugular dislocation, fronto-sphenoid compression, lateral sphenoid strain, lowered cranial rhythmic impulse and impairment of venous sinus drainage. Physical examination reveals TMJ dysfunction which is supported by an MRI, documenting a dislocated/ torn disc and capsule allowing for complete dislocation of the TMJ disc during opening and closing. Cervical MRI demonstrates atrophy of the rectus capitis superior minor muscle with resultant instability of the occipito-atlantal joint. Neural and myofascial tension is noted from the anterior cervical regions down the right arm into the wrist and hand. The diaphragmatic breathing pattern is markedly dysfunctional with dyskinesis of the thoracic, pelvic, and cranial diaphragms. Hypermobility of the cervical and thoracic ligaments is noted at multiple levels. The sacrum and coccyx are abnormally tight and intra-osseously compressed with a backward sacral torsion. A right pelvic shear is evidenced by the asymetrical positions of the ischial tuberosities. “Listening” reveals a restricted and mildly ptosed left kidney. The liver’s mobility and motility are also restricted. The treatment of the above structural somatic dysfunctions would require skilled interventions with cranial manipulation, visceral manipulation, prolotherapy, neuro-fascial release, myofascial release, and temporomandibular joint treatment from a dentist familiar with cranial- mandibular mechanics (severe TMJ pathology may require surgery). Many of these patients benefit from the intelligent use of nutraceutical products including: vitamins, minerals, trace minerals, enzymes, amino acids, anti-oxidants, and herbs. Magnesium, zinc, vitamin C, proline, and a host of other nutrients are necessary for connective tissue integrity. Chronic inflammation can be treated with an anti-inflammatory diet (Mediterranean diet minus their food sensitivities) along with therapeutic levels of Omega-3 fatty acids, boswellia serrata, tumeric, bromelain, ginger, garlic, devil’s claw, MSM, CoQ10, and alpha lipoic acid. Several companies offer intracellular nutrient testing to specifically identify deficiencies. The hypothalamic-pituitary-adrenal axis is universally stressed and often dysfunctional posttraumatically. Patients need a thorough examination of their endocrine system to determine the extent of abnormal hormonal involvement. The most common finding is adrenal dysfunction: either hyperactivity or exhaustion. Continuous stress on the adrenal system leads to fatigue, depression, idiopathic rashes, paradoxical wakefulness at night, sugar and stimulant cravings, gastrointestinal irritation, weakened ligaments, dilated pupils, orthostatic hypotension, susceptibility to infections, and marked susceptibility to joint injuries. B- complex vitamins, vitamin C, minerals, ginseng, gotu kola, saspirilla, rehmannia, adrenal glandular products, and selective Chinese herbal formulas can help restore energetic and metabolic balance to the gland. Occasionally, the patient will require physiologic doses of Cortisone (Cortef). Thyroid dysfunctions are very common and often present after severe stress or trauma particularly to the head and neck. In general, any gland may exhibit post-traumatic dysfunction. The pancreas may become hypo-functioning on an endocrine or exocrine basis. Menstrual irregularity may follow head or back injury. Each case is unique and needs to be evaluated for possible deleterious sequelae.. Ideally, successful manipulation of “ key lesions”, dietary adjustments, individualized nutritional and herbal therapies and acupuncture can provide considerable relief and improvement to their former condition. 6 One can not underestimate the importance of also treating the mental-emotional, psychic, etheric, and spiritual dimensions of trauma. As triune beings we resonate in accordance to the health and balance of our mind-body-spirit. Treating the subtler energy fields can at times produce the greatest changes in our patients. Many patients are stuck in their fixed attitude, posture, and energy resonance. EMDR, Bach Flower Remedies, Homeopathy, Hypnosis, Reiki, Hands of Light, Chinese Medicine, and other modalities on “The List” work with those dimensions that are rarely acknowledged by conventional medical treatments. Dr. Fulford said that the goal of the healer is to help the patient find their destiny. To put the patient in touch with what their ultimate purpose was for being on this earth in this lifetime. Once a patient is doing what they were meant to do, everything else begins to fall in place. Sometimes trauma is a gift that leads to an awareness of what is important and what needs to be done. Trauma can occur in “ one fell swoop” or as the “straw that breaks the camel’s back.” Repetition stress is commonplace and what I see in my practice is a body finally running out of adaptations. We see this often in children today playing sports or having a series of injuries where each one leads to an adaptive response that eventually can’t compensate. Too often, parents are told that their child athlete is fine and will ”get over it” because he’s just a kid. Soccer trauma, gymnastics injuries, and all the other trauma prone sports are creating a nation of “walking wounded child-athletes“ who are only given ice and ibuprofen for their aches and pains. Very little attention is paid to the specific, discrete nature of their injuries that can be treated by competent manual medicine practitioners and/or acupuncturists. A child might present with headaches or neck pain that is the result of untreated ankle or lower back strains from past injuries. The athlete will keep compensating for their previous injury with altered posture and motion mechanics which will ultimately take them down a path of new injuries. Gaining the skills to diagnose and treat somatic dysfunctions as they occur in the child or adult proves rewarding to the patient and doctor alike. “An ounce of prevention is worth a pound of cure” and treating and resolving trauma in a timely fashion can restore function and prevent a lot of unnecessary pain and suffering down the road. Trauma: An Osteopathic Approach authored by Jean-Pierre Barral D.O. and Alain Croiber D.O. is an outstanding text for exploring the varied depths and multi-dimensional consequences of trauma. “Nothing is forgotten”, ”Nothing is isolated”, “Everything accumulates”, “Everything is recorded”, summarizes several critical concepts that are at the foundation of traditional osteopathic thought. All structures and tissues do not respond identically to the same given traumatic forces. The pre-existing state of the person’s mind/body/spirit influences the outcome of any traumatic event. Barral and Crobier describe in great detail the biomechanics and physics of trauma. Each system of the body is included in their analysis. Novel diagnosis and treatment procedures are presented for treating: cranial, dural, visceral, neural, vascular, and osteoarticular injuries. (Several of these modalities are presented in the powerpoint presentation). Foundations for Integrative Musculoskeletal Medicine: An East-West Approach authored by Alon Marcus D.O.M., L.Ac., D.A.A.P.M. is certainly one of the most comprehensive texts I’ve ever read regarding the musculoskeletal system. Dr. Marcus has done an amazing job of merging orthopaedic, neurological, and osteopathic principles of diagnosis and treatment with that of Chinese Medicine; both acupuncture and herbal medicine. A wonderful reference text for almost any clinical presentation in musculoskeletal medicine. Enjoy! Jay Sandweiss D.O., C-NMM/OMM, F.A.A.M.A. 7 8 9 Do the Prescriptions You Take Deplete Your Nutritional Status? SOURCE: DRUG-INDUCED NUTRIENT DEPLETION HANDBOOK, 2ND EDITION NUTRIENT DEFICIENCY POTENTIAL HEALTH PROBLEM Vitamin B12 Folic Acid Vitamin D Calcium Iron Zinc Anemia, depression, tiredness, weakness, increased cardiovascular risk Birth defects, cervical dysplasia, anemia, heart disease, cancer risk Osteoporosis, muscle weakness, hearing loss Osteoporosis, heart and blood pressure irregularities, tooth decay Anemia, weakness, fatigue, hair loss, brittle nails Weak immunity, wound healing, sense of smell/taste, sexual dysfunction B Vitamins Vitamin K Short term depletion affects are minimal, but failure to re-inoculate the GI tract with beneficial bacteria (probiotics) often results in dysbiosis which causes gas, bloating, decreases digestion & absorption of nutrients, and also may lead to a variety of other health problems. Tetracyclines Calcium Magnesium Iron Vitamin B6 Zinc Osteoporosis, heart & blood pressure irregularities, tooth decay Cardiovascular problems, asthma, osteoporosis, cramps, PMS Slow wound healing, fatigue, anemia Depression, sleep disturbance, increased cardiovascular disease risk Weak immunity, wound healing, sense of smell/taste, sexual dysfunction CHOLESTEROL DRUGS Coenzyme Q10 Various cardiovascular problems, weak immune system, low energy Coenzyme Q10 Vitamin B2 Various cardiovascular problems, weak immune system, low energy Problems with skin, eyes, mucous membranes and nerves Vitamin B6 Depression, sleep disturbance, increased cardiovascular disease risk Oral Contraceptives Folic Acid Vitamin B1 Vitamin B2 Vitamin B3 Vitamin B6 Vitamin B12 Vitamin C Magnesium Selenium Zinc Birth defects, cervical dysplasia, anemia, cardiovascular disease Depression, irritability, memory loss, muscle weakness, edema Problems with skin, eyes, mucous membranes and nerves Cracked, scaly skin, swollen tongue, diarrhea Depression, sleep disturbances, increased cardiovascular disease risk Anemia, depression, tiredness, weakness, increased cardiovascular risk Lowered immune system, easy bruising, poor wound healing Cardiovascular problems, asthma, osteoporosis, cramps, PMS Lower immunity, reduced antioxidant protection Weak immunity, wound healing, sense of smell/taste, sexual dysfunction ANTICONVULSANTS Vitamin D Calcium Folic Acid Biotin Carnitine Vitamin B12 Vitamin B1 Vitamin K Copper Selenium Zinc Osteoporosis, muscle weakness, hearing loss Osteoporosis, heart & blood pressure irregularities, tooth decay Birth defects, cervical dysplasia, anemia, cardiovascular disease Hair loss, depression, cardiac irregularities, dermatitis Various cardiovascular problems, weak immune system, low energy Anemia, depression, tiredness, weakness, increased cardiovascular risk Depression, irritability, memory loss, muscle weakness, edema Blood coagulation, skeletal problems Anemia, fatigue, cardiovascular and connective tissue problems Lower immunity, reduced antioxidant protection Weak immunity, wound healing, sense of smell/taste, sexual dysfunction DRUG ANTACIDS/ULCER MEDICATIONS Pepcid, Tagamet, Zantac, Prevacid, Prilosec, Magnesium & Aluminum antacids ANTIBIOTICS Gentomycin, neomycin,streptomycin, cephalosporins, penicillins Lipitor, Crestor, Zocor, and others ANTI-DEPRESSANTS Adapin, Aventyl, Elavil, Pamelor, & others Major Tranquilizers (Thorazine, Mellaril, Prolixin, Serentil & others) FEMALE HORMONES Estrogen/Hormone Replacement Phenobarbital & barbituates Dilatin, Tegretol, Mysoline Depakane/Depacon Copyright 2009 SpectraCell DOC Copyright © 2008© SpectraCell Laboratiores, Inc.Laboratories All Rights Reserved. FIA 306306-01.09 - 12.08 ( 5227) Visitususatat www.spectracell.com Visit www.spectracell.com ororcall callususatat 800.227.LABS 800.227.5227 10 ADVANCED CLINICAL TESTING ADVANCED CLINICAL TESTING Do the Prescriptions You Take Deplete Your Nutritional Status? SOURCE: DRUG-INDUCED NUTRIENT DEPLETION HANDBOOK, 2ND EDITION NUTRIENT DEFICIENCY POTENTIAL HEALTH PROBLEM Calcium Vitamin D Magnesium Zinc Vitamin C Vitamin B6 Vitamin B12 Folic Acid Selenium Chromium Osteoporosis, heart and blood pressure irregularities, tooth decay Osteoporosis, muscle weakness, hearing loss Cardiovascular problems, asthma, osteoporosis, cramps, PMS Weak immunity, wound healing, sense of smell/taste, sexual dysfunction Lowered immunity, easy bruising, poor wound healing Depression, sleep disturbances, increased cardiovascular disease risk Anemia, depression, tiredness, weakness, increased cardiovascular risk Birth defects, cervical dysplasia, anemia, cardiovascular disease Lower immunity, reduced antioxidant protection Elevated blood sugar, cholesterol & triglycerides, diabetes risk NSAIDS (Motrin, Aleve, Advil, Anaprox, Dolobid, Feldene, Naprosyn and others Folic Acid Birth defects, cervical dysplasia, anemia, cardiovascular disease Aspirin & Salicylates Vitamin C Calcium Folic Acid Iron Vitamin B5 Lowered immune system, easy bruising, poor wound healing Osteoporosis, heart & blood pressure irregularities, tooth decay Birth defects, cervical dysplasia, anemia, cardiovascular disease Anemia, weakness, fatigue, hair loss, brittle nails fatigue, listlessness, and possible problems with skin, liver and nerves DIURETICS Calcium Magnesium Vitamin B1 Vitamin B6 Vitamin C Zinc Coenzyme Q10 Potassium Sodium Osteoporosis, heart and blood pressure irregularities, tooth decay Cardiovascular problems, asthma, osteoporosis, cramps, PMS Depression, irritability, memory loss, muscle weakness, edema Depression, sleep disturbance, increased heart disease risk Lowered immunity, easy bruising, poor wound healing Weak immunity, wound healing, sense of smell/taste, sexual dysfunction Various cardiovascular problems, weak immune system, low energy Irregular heartbeat, muscle weakness, fatigue, edema Muscle weakness, dehydration, memory problems, loss of appetite Potassium Sparing Diuretics Calcium Folic Acid Zinc Osteoporosis, heart & blood pressure irregularities, tooth decay Birth defects, cervical dysplasia, anemia, cardiovascular disease Weak immunity, wound healing, sense of smell/taste, sexual dysfunction CARDIOVACSULAR DRUGS Coenzyme Q10 Vitamin B6 Zinc Vitamin B1 Various cardiovascular problems, weak immune system, low energy Depression, sleep disturbance, increased cardiovascular disease risk Weak immunity, wound healing, sense of smell/taste, sexual dysfunction Depression, irritability, memory loss, muscle weakness, edema ACE Inhibitors (Capoten, Vasotec, Monopril & others) Zinc Weak immunity, wound healing, sense of smell/taste, sexual dysfunction Bete Blockers (Inderal, Corgard, Lopressor and others) Coenzyme Q10 Various cardiovascular problems, weak immune system, low energy DRUG ANTI-INFLAMMATORIES Corticosteriods: Prednisone, Medrol, Aristocort, Decodron Loop Diuretics (Lasix, Bumex, Edecrin) Thiazid Diuretics (HCTZ, Enduron, Diuril, Lozol, Zaroxolyn, Hygroton and others Antihypertensives (Catapres, Aldomet) DIABETIC DRUGS Metformin Sulfonylureas (Dymelor, Tolinase, Micronase/Glynase/DiaBeta) ANTIVIRAL AGENTS Zidovudine (Retrovir, AZT & other related drugs) Foscarnet Coenzyme Q10 Vitamin B12 Folic Acid Various cardiovascular problems, weak immune system, low energy Anemia, depression, tiredness, weakness, increased cardiovascular risk Birth defects, cervical dysplasia, anemia, heart disease, cancer risk Coenzyme Q10 Various cardiovascular problems, weak immune system, low energy Increased blood lipids, abnormal liver function and glucose control Anemia, fatigue, cardiovascular and connective tissue problems Weak immunity, wound healing, sense of smell/taste, sexual dysfunction Anemia, depression, tiredness, weakness, increased cardiovascular risk Osteoporosis, heart and blood pressure irregularities, tooth decay Cardiovascular problems, asthma, osteoporosis, cramps, PMS Irregular heartbeat, muscle weakness, fatigue, edema Copyright © 2007 SpectraCell Laboratiores, Inc. All Rights Reserved. Carnitine Copper Zinc Vitamin B12 Calcium Magnesium Potassium Copyright © 2008 SpectraCell Laboratiores, Inc. All Rights Reserved. FIA 306 - 02.08 Copyright © 2009 SpectraCell Laboratories DOC 306-01.09 Visit at at www.spectracell.com or call call us us at 800.227.5227( 5227) Visitusus www.spectracell.com or at 800.227.LABS 11 ADVANCEDCLINICAL CLINICALTESTING TESTING ADVANCED Disclosure: Nothing to disclose Dr. George J. Goodheart 1 12 Dr. David Walther The goal of manipulation is to restore maximal pain-free movement of the musculo-skeletal system in postural balance. Test: Latissimus Dorsi Tightness creates and weakness permits asymmetry. Weakness creates and tightness maintains asymmetry. 2 13 MUSCLE-MERIDIAN RELATIONSHIPS: • SUPRASPINATUS=CONCEPTION VESSEL • TERES MAJOR=GOVERNING VESSEL • DELTOID=LUNG • TENSOR FASCIA LATA= LARGE INTESTINE • PECTORALIS MAJOR CLAVICULAR= STOMACH • LATISSIMUS DORSI=PANCREAS • SUBSCAPULARIS=HEART • QUADRICEPS=SMALL INTESTINE MUSCLE-MERIDIAN RELATIONSHIPS: • PERONEUS TERTIUS=BLADDER PSOAS= KIDNEY • GLUTEUS MEDIUS=MASTER OF THE HEART • TERES MINOR=TRIPLE ENERGIZER • POPLITEUS=GALL BLADDER • PECTORALIS MAJOR STERNAL= LIVER • 14 MUSCLE-MERIDIAN DANCE • MUSCLE WEAKNESS AS AN INDICATOR OF MERIDIAN PROBLEM • LOCATION OF SPINAL SEGMENTAL SOMATIC DYSFUNCTION AS INDICATOR OF MERIDIAN PROBLEM (SHU POINT) 3 14 Visceral Manipulation for Liver! Mobility (seated)! Reproduced with permission from Visceral Manipulation! Revised Edition, Eastland Press! 4 15 5 16 Reproduced from A MANUAL OF ACUPUNCTURE by Peter Deadman 6 17 Acupuncture points and their associated channels exist in anatomical locations that can be influenced by manual medicine interventions. Manual medicine treatments can be utilized before or after acupuncture needling to enhance the total therapeutic effort. 7 18 8 19 Acupuncturists may wish to apply manual therapies to specific body regions that have seemed refractory or difficult to treat with acupuncture alone. Likewise, manual medicine practitioners may wish to utilize acupuncture when their manipulative efforts are insufficient at producing a satisfactory response in the patient. 9 20 Barrier Concept: Define your problems before you can hope to fix them Biomechanical: Employed to restore local Arthrodial motion loss Respiratory-Circulatory: • Change in PEFR in COPD and Asthma patients after thoracic HVLA • Gordon Zink Neurological: Metabolic-Energetic: • WAKE UP the autonomics segmentally • T 4 (Larsens) Syndrome • Trickle down from improved neuro, resp, circulatory 10 21 MANUAL MEDICINE TECHNIQUES THAT TREAT CHANNEL RESTRICTIONS MANUAL MEDICINE TECHNIQUES THAT TREAT CHANNEL RESTRICTIONS •! SMALL INTESTINE: SI-11,13,14 COUNTERSTRAIN , SI-19 TMJ RELEASES •! CONCEPTION VESSEL: CV-17 COUNTERSTRAIN •! GOVERNING VESSEL: GV-1 COUNTERSTRAIN, GV-20 CRANIAL •! LUNG: LU- 1&2 COUNTERSTRAIN, LU-7-9 MYOFASCIAL RELEASE •! BLADDER: ANY SPINAL LEVEL ( e.g. BL-23) MET/ COUNTERSTRAIN •! LARGE INTESTINE: LI-4 UNWIND THUMB, LI-11 COUNTERSTRAIN/ MFR •! KIDNEY: KI-10 COUNTERSTRAIN, KI-27 MET •! STOMACH: ST-41 MUSCLE ENERGY TECHNIQUE OR THRUST TECHNIQUE •! SPLEEN: SP-2,3,4 MYOFASCIAL RELEASE OR MUSCLE ENERGY TECHNIQUE •! HEART: HT-1 ACTIVATED RELEASE, HT-3 COUNTERSTRAIN OR THRUST •! TRIPLE ENERGIZER: TE-10, 11, 12 DEEP MYOFASCIAL RELEASE •! GALL BLADDER: GB-34,40 MET TO FIBULA, GB-20 MET OR COUNTERSTRAIN, GB-21 COUNTERSTRAIN OR MYOFASCIAL RELEASE •! LIVER: LR-2,3 MFR OF TOE, LR-4 MFR OF ANKLE MORTISE, LR-14 VISCERAL Osteopathic Manipulation! Special Attention to:! • Breathing (3 Diaphragms)! • Visceral Mobility and Motility disorders! • Sacrum-Coccyx(Holds fear/insecurity)! • Dural strains! • Cranial/TMJ dysfunctions (often unexamined)! • Greenman’s “Dirty Half-dozen” (non-neutral facet joint restrictions, symphysis pubis shears, sacral posterior torsion or nutation, hip bone shear, short-leg/pelvic tilt syndrome, and muscle imbalance of the trunk and extremities)! • Nerve Restrictions! • “Energy Sinks” (Robert Fulford’s Concept that is treated with the Percussion Vibrator)! Myofascial Release! Muscle Energy Technique! Strain-Counterstrain! Functional Release! Cranial Osteopathy! High Velocity Technique! Visceral Manipulation! Still Technique! Facilitated Position Release! Balanced Ligamentous Tension! Percussion Hammer! Cranial! Diaphragm! Thoracic! Diaphragm! 11 22 Listening with traction on the! Cylinder of the dura mater! Pelvic! Diaphragm! Visceral Manipulation for Liver! Mobility (seated)! Reproduced with permission from Visceral Manipulation! Revised Edition, Eastland Press! Muscle Energy! Position For Treatment of An L2-ERSR! Patient Pulls Right Scapula Down Toward Doctor’s Finger With Slight Right Rotation! 12 23 At the spinal level, attention to several! attachments of the dura mater is required! for successful osteopathic manipulation:! •! Foramen magnum! •! C2! •! Sacrum! •! Coccyx! •! Vertebral foramen! Acute Low Back Pain in a NCAA Division I Basketball Player Resolves with One Acupuncture Treatment and Osteopathic Manipulation Jay Sandweiss D.O., C-NMM/OMM, F.A.A.M.A. Abstract Background: Lumbo-sacral and/or sacroiliac sprain/strains are common afflictions affecting competitive basketball players.1 Star athletes and their coaching staff seek fast effective treatment modalities for their injuries to facilitate a full and speedy return to the game. Objective: This case demonstrates an immediate resolution of low back pain in a college basketball player utilizing acupuncture and osteopathic manipulation in one treatment. Intervention: The patient was treated once with acupuncture and osteopathic manipulation the day of a Big Ten basketball game. One treatment resolved his painful movement, motion loss, antalgic body posture and right-sided lumbago. Patient was given samples of Traumeel ointment (homeopathic) to apply later that day. The player refused using any pharmacological medications (including Ibuprofen) as he was philosophically opposed to Western allopathic drugs. 13 24 INTRODUCTION Main Outcome Measure: Resolution of disabling pain, painful movement, motion restriction, antalgic posture, right-sided low back pain. Results: Resolution of all symptoms with one treatment of medical acupuncture combined with osteopathic manipulation. The patient played six hours post treatment in a NCAA Division I basketball game without evidence of symptoms. In fact, his performance was one of his best of the season. Case Report: This author received a midday contact from a Division I basketball staff member requesting immediate treatment for an acutely injured player. Schedules were adjusted and the player was seen in my office shortly thereafter for acute right–sided low back pain. The pain had started the previous day and now made him unable to stand upright, have difficulty rising from a chair, and have spasms in the right sacroiliac, right gluteal/buttock and right lumbo-sacral areas. He was supposed to play in the starting line-up that same evening six hours later. The patient could not recall the exact etiology of the injury, but had fallen several times while leaping for a ball or from being fouled during a play. The training staff had attempted to stretch him out and provided ice and modalities that had not resolved this issue. X-ray studies taken earlier that day of his lumbar, sacral, and sacroiliac regions were negative for pathology. Conclusions: This case demonstrates that an acutely symptomatic injured athlete can be successfully treated with a single treatment of acupuncture and osteopathic manipulation and return to full capacity that same day. Certainly this particular situation does not reflect all soft tissue conditions but it serves to respect the potential for immediate resolution of injury and inactivity. Objective physical findings: 22-year-old African-American male with a postural list to the right, walking with apprehension when loading weight to the right hip. Decreased extension of lumbar spine and sacrum. Difficulty rising from a chair. Marked tension and trigger points present in right gluteus medius/minimus, piriformis, quadratus lumborum, and psoas muscles. Patient received osteopathic manipulation to the above somatic dysfunctions using Muscle Energy Technique, High Velocity Low Amplitude Thrust and Myofascial Release. 2,3 The acupuncture treatment combined Neuro-Anatomical principles with Tendinomuscular meridian and Curious meridian activation. Positive right standing and seated flexion screening tests for PSIS motion asymmetry. Right hip crest inferior while standing. Upslipped right innominate. Right on left sacral torsion. L3-FRSR, L5- FRSR. Weakness of right hip abductors 4-/5. Mild right innominate rotation. C2-FRSL, C3-FRSR. Pain pattern distribution and “Ashi “tender points located along the trajectory of Tai Yang channel. Needles used: Spring Ten Handle 0.20X30mm sterile disposable acupuncture needles with insertion tube. Point selection: Left SI-3, Right BL-62, 67 Bilateral BL-21, 22, 23, 24, 26, 27, 28, 31, 36, 52, 40 GV-3, 4 Right BL-53, 54 Electroacupuncture Device: Pantheon Research PENS Electrostimulator 12c. Pro Model Electrical stimulation was applied at a frequency of 25Hz to 10 points bilaterally: BL-21, 22, 23, 24, 28 BL- 53, 54 were stimulated at 25Hz right side only Acupuncture treatment time: 25 minutes 14 25 Discussion: Acute low back pain arising from sprain and /or strain of soft tissues is a common presentation from highly competitive athletes. This patient received care using both osteopathic manipulation and electrical acupuncture during the same treatment session.4 The patient received acupuncture using electrical stimulation at a frequency of 25 Hz. This frequency has been highly effective for treating pain and muscle weakness due to athletic injury in this author’s experience.5 Both forms of treatment have shown efficacy in treating acute low back pain.6,7,8 The proposed mechanisms of action for both interventions involve the activation of several sites in the central and autonomic nervous system as well as receptors in the peripheral nervous system. The release of peptides, neurotransmitters and endogenous opioids is well studied. 9,10,11 Neuro-imaging studies with fMRI, performed by Vitaly Napadow PhD et al, suggest that neuroplasticity changes occur in the brain with acupuncture treatment.12 This suggests yet another neuromodulatory effect distinct from the previously noted mechanisms. At the AAMA 26th Symposium, Narda Robinson, D.O., D.V.M. reviewed the theory of acupuncture treatments inducing changes in the cytoarchitecture of fibroblasts and the metabolism of connective tissue components. She went on to describe the effects of acupuncture on the fascia “within and between cells in the extracellular matrix” affecting multiple functions such as: nutrient transfer, nerve signal transduction, regulation of intercellular communication, and the transmission of mechanical stresses on the fibroblast cytoskeleton. Her lecture further emphasized the similar effects achieved from acupuncture, Yoga, and massage(manipulation) to alter fibroblast activity and “change stiffness and viscosity of connective tissue within minutes”. Finally, Dr. Robinson discussed the concept of “Fascial Acupuncture” that sees the acupuncture channels as fascial planes.13 As fascia envelops all structures in the body, one can postulate the possibility of acupuncture stimulation modulating physiology through this vast intricate network of fascia as described by Finando et al.14 Results: During his acupuncture treatment the patient frequently described a relaxing euphoric feeling that made his muscles and pain release. After standing up from the acupuncture treatment his posture was erect and symmetrical. All pain with motion was gone. Rising from a chair and walking were painless. Six hours later the patient played outstanding basketball without any evidence of pain or gait disturbance. This author had the pleasure of attending that game. Two Weeks of Recalcitrant Cervical Pain, Weakness, and Restricted Motion in an Olympic Wrestler, Successfully Treated with Acupuncture and Osteopathic Manipulation Conclusion: Acute soft tissue sport injuries are commonly treated with the PRICE formula (Protect, Rest, Ice, Compress, Elevate) or some variation of that theme.15 Nonsteroidal anti-inflammatory medications, massage, and physical therapy modalities are frequently used by athletic departments when treating their injured athletes.16 Severe injuries may require surgery, injections, bracing or a prolonged period of rest. This particular case demonstrates the effectiveness of a single treatment utilizing medical acupuncture and osteopathic manipulation to quickly and effectively resolve pain, weakness, spasm and motion restriction with asymmetry in an acutely injured basketball player. Clearly not all athletic injuries can be expected to respond immediately to a single treatment. However, this case shows the potential for impressive results to occur with only one treatment in an acute setting. Perhaps more professional and college teams will consider the benefits of adding this treatment approach to their current armamentarium. Jay Sandweiss D.O., C-NMM/OMM, F.A.A.M.A. Abstract Background: Cervical sprain/strain is a common condition afflicting athletes participating in aggressive contact sports.1 Competitive athletes often seek immediate results that allow for a rapid return to full activity and high performance levels. Objective: This case demonstrates a swift resolution of cervical pain, weakness, and restricted motion in an Olympic wrestler utilizing acupuncture and osteopathic manipulation. Intervention: The patient was treated with acupuncture and osteopathic manipulation four times over a course of five days. Eighty percent improvement was achieved immediately following the initial treatment. Patient was prescribed a nutraceutical product to use for soft tissue inflammation (See Appendix A). . Main Outcome measure: Resolution of pain, weakness, and restricted motion of cervical spine region. Results: Total resolution of all symptom parameters was achieved after three treatments. The fourth acupuncture treatment was given for mind-body focus only. This patient went to the final U.S.A. Olympic trials two days post treatment and won his weight division. He represented the U.S.A. at the 2012 Olympic games in London, England. Conclusions: This case suggests that acupuncture treatment with osteopathic manipulative treatment can accelerate soft tissue injury resolution time. Athletes may be able to return to full activity levels sooner than they would have using more conservative treatment modalities. Randomized controlled trials are indicated 15 26 MANUAL MEDICINE! PROCEDURES AND ! NUTRITIONAL/HERBAL! THERAPIES AS THEY! APPLY TO ACUPUNCTURE! POINT AREAS! Reproduced from A MANUAL OF ACUPUNCTURE by Peter Deadman Muscle Energy Treatment: Posterior Fibular Head! Muscle Energy Treatment: Anterior Fibular Head! Pearls of GB- 34 : COMMON ISSUES: ! Gallbladder Symptoms, Tendon /Joint Problems, Headaches, Fibula Issues at Knee and Ankle, IlioTibial Band Syndrome CHECK: ! BIle Salts, Bile Thinners (Vitamin A, Beet leaf juice extracts, dandelion root), Iodine need, Feverfew, Silymarin, Schizandra, Choline Reproduced from A MANUAL OF ACUPUNCTURE by Peter Deadman 16 27 Pearls of LI - 11 : COMMON ISSUES: ! Facial Flushing, Heat Signs, Upper Limb and Elbow Pain, Large Intestine Issues: Colitis, Irritable Bowel,Toxic Bowel, “Tennis Elbow” Counterstrain Tx:! Radial Head (Tennis Elbow)! CHECK: ! Stool Analysis, Probiotics, Bowel Detoxification, Radial Head, Enzymes, Chronic Candida Quadratus Lumborum Reproduced from A MANUAL OF ACUPUNCTURE by Peter Deadman Strain-! Counterstrain! Strain-! Counterstrain! Treatment of Posterior Lumbar TPs! Posterior Lumbar Transverse Process (TP)! Treatment of Posterior Lumbar Spinous and ! Medial TPs! 17 28 Pearls of BL-23 COMMON ISSUES: Low Back Pain, Weak Back, Easily Chilled, Decreased Libido, Fear and Insecurity, Knee Problems, Dental Problems, Infertility, Erectile Dysfunction, Chronic Fatigue, Sore Throats, Chronic Illness, Ear Problems, Tinnitus, Genito-Urinary Issues CHECK: Rehmannia, Adrenal Formulas, Ginseng, Tribulus, Astragalus, Vitamin A, Vitamin C, Uva Ursi, Cranberry Extracts, Licorice, Rhodiola, Withania Gluteus Maximus Reproduced from A MANUAL OF ACUPUNCTURE by Peter Deadman Pectoralis Major - Sternal Strain-! Counterstrain! Treatment of High Ilium With Flare-Out Left! Good For Coccydynia! 18 29 Pectoralis Major - Clavicular Subclavius Subclavius Reproduced from A MANUAL OF ACUPUNCTURE by Peter Deadman Screening Test for S-C Joint Restriction (Patient Shrugs)! MET Tx For S-C Joint! Dx: Restriction of Inferior Glide! 19 30 Abdominals Rectus abdominals Inferior Abdominals Inferior Middle Triceps Brachii and Anconeus Visceral Manipulation for Liver! Mobility (seated)! Reproduced with permission from Visceral Manipulation! Revised Edition, Eastland Press! Direct Myofascial release to Triceps Fascia! Reproduced from A MANUAL OF ACUPUNCTURE by Peter Deadman 20 31 Pronator Teres Reproduced from A MANUAL OF ACUPUNCTURE by Peter Deadman Counterstrain Tx:! Radial Head (Tennis Elbow)! Hamstring Peroneus Longus and Brevis Reproduced from A MANUAL OF ACUPUNCTURE by Peter Deadman 21 32 Muscle Energy Treatment: Posterior Fibular Head! Muscle Energy Treatment: Anterior Fibular Head! Peroneus Tertitus Reproduced from A MANUAL OF ACUPUNCTURE by Peter Deadman Gastrocnemius Reproduced from A MANUAL OF ACUPUNCTURE by Peter Deadman 22 33 Tibialis Anterior Muscle Energy Treatment: Distal Fibula (Pump Ankle)! Myofascial Release of Ankle Mortise (seated)! Reproduced from A MANUAL OF ACUPUNCTURE by Peter Deadman Extensor Hallucis Longus and Brevis High Velocity: Anterior Talus Manipulation! 23 34 Flexor Hallucis Longus Reproduced from A MANUAL OF ACUPUNCTURE by Peter Deadman Myofascial Release of Great Toe! CERVICAL REGION PEARLS CERVICAL REGION PEARLS •! PROBLEMS OF THE CERVICAL SPINE REGION CAN COME FROM ANYWHERE! •! SACROILIAC FIXATIONS = INHIBIT POSTERIOR CERVICAL EXTENSOR MUSCLES •! COMMON NEUROMUSCULOSKELETAL CAUSES OF THESE PROBLEMS INCLUDE: •! CRANIAL FIELD SOMATIC DYSFUNCTIONS ( JUGULAR FORAMEN: CN9,10,11) •! VISUAL DISORDERS •! (OFTEN UNDIAGNOSED VERTICAL HETEROPHIA OR OTHER VISUAL PERCEPTUAL DEFECTS), TMJ AND HYOID BONE DYSFUNCTIONS. •! THESE MUST BE IDENTIFIED AND TREATED TO ACHIEVE LASTING CORRECTIONS •! LOVETT BROTHER REACTIVITY: SACRUM=OCCIPUT, L5=C1, L4=-C2, L3=-C3, L2=C5, L1=-C6 •! UPPER THORACIC VERTEBRA, RIBS, AND UPPER EXTREMITIES GREATLY INFLUENCE CERVICALS •! VISCERAL PTOSIS (USUALLY KIDNEY OR LIVER) OR VISCERAL RESTRICTIONS FROM THE THORAX(PLEURA/LUNG) CAN CREATE OR PERPETUATE CERVICAL SYNDROMES •! AFTER WHIPLASH INJURY NEED TO TREAT DIAPHRAGM, DURAL STRAINS, CRANIAL DYSFUNCTION ( OFTEN PETROJUGULAR DISLOCATION), LOCAL SOFT TISSUES: MUSCLE SPINDLE CELLS, FASCIA, MUSCLES, GOLGI TENDONS 24 35 CERVICAL REGION PEARLS CERVICAL REGION PEARLS OTHER IDEAS TO CONSIDER: • POSTURAL ERGONOMICS: • “THE HEAD IS A HEAVY BOWLING BALL” ALEXANDER TECHNIQUE, WORKSITE EVALUATION, POSTURAL TRAINING MAY ALL BE NECESSARY • ALL ACUPUNCTURE CHANNELS AND POINTS IN THE HEAD AND NECK REGION ARE YANG EXCEPT FOR THE CONCEPTION VESSEL IN THE VENTRAL MIDLINE • GAIT AND LOWER EXTREMITY INVOLVEMENTS: SHORT LEG, FOOT PRONATION, TIGHT TALOCRURAL MOTION, ASYMMETRICAL GAIT SWING, “WALKING GAIT” DISORDERS CAN ALL CAUSE OR PERPETUATE CERVICAL PROBLEMS • 4 OF THESE YANG CHANNELS ARE CONNECTED TO THE EYES ( BL, ST, TH AND GB) • 4 OF THESE YANG CHANNELS ARE CONNECTED TO THE TMJ REGION (SI,ST,TH, AND GB) CERVICAL REGION PEARLS CERVICAL REGION PEARLS OTHER IDEAS TO CONSIDER: OTHER IDEAS TO CONSIDER: • DISTURBANCES IN ANY OF THESE CHANNELS CAN BE A CAUSE OF CHRONIC CERVICAL COMPLAINTS. DISTURBANCES CAN INVOLVE ORGANS AND GLANDS ASSOCIATED WITH THOSE CHANNELS. ( EXAMPLE: GERD MAY BE CAUSED BY”REBELLIOUS STOMACH QI”. GERD MAY CAUSE SORE THROAT OR OTHER SYMPTOMS IN THE CERVICAL/TMJ AREA WHICH FOLLOW THE TRAJECTORY OF THE UPPER STOMACH MERIDIAN.) THIS IS ANOTHER WAY OF UNDERSTANDING VISCERO-SOMATIC PAIN PATTERNS. GALL BLADDER MERIDIAN PROBLEMS MAY PRESENT AS NECK OR SHOULDER PAIN • “BOTTLE NECK”: CONNECTOR BETWEEN THE HEAD (MIND) AND BODY (HEART) BECOMES SYMPTOMATIC WHEN THERE IS CONFLICT BETWEEN MIND AND EMOTION • SADNESS AND GRIEF STORED THERE • REPRESENTS THE INHERENT FLEXIBILITY TO SEE BOTH SIDES OF AN ISSUE • THE NECK IS A VULNERABLE, SENSITIVE AREA: CAROTID ARTERIES, THYROID, PARATHYROIDS, TRACHEA, SPINAL CORD VAGUS AND PHRENIC NERVES 25 36 UPPER EXTREMITY PEARLS UPPER EXTREMITY PEARLS Multiple reflex systems affect the upper extremity from the opposite side of the body: Muscle Interlink Ligament Interlink Gait Reflexes/Brain Cortex Acupuncture Meridians: Inverse /Contrary pairings Shoulder = Opposite Hip Elbow = Opposite Knee Wrist = Opposite ankle Fingers = Opposite toes Upper Extremity = Opposite Cortex (80%) Upper extremity problems may be locally and/or distally induced and perpetuated Always evaluate the whole patient/whole body for somatic dysfunctions of the spine, ribs, cranium, pelvis, sacrum and lower extremities Muscle testing helps identify the source of many problems. It helps to gauge the success of treatment by testing pre and post muscle response Many upper extremity issues come from cervical and upper thoracic/rib somatic dysfunctions Yang Meridians run from fingers to face (Large Intestine - Small Intestine - Triple Warmer) Think brachial plexus trouble makers (cervical spine, T1, scalenes, upper ribs) Yin Meridians run from trunk to fingers (Heart – Lung – Pericardium) UPPER EXTREMITY PEARLS LOWER EXTREMITY PEARLS ! Organ and meridian disturbances create upper extremity problems by referral through reflexes and channels • ALWAYS EXAMINE THE WHOLE PERSON FROM TOP TO BOTTOM AND FROM BOTTOM TO TOP. BRAIN, SPINE, AND PELVIS MUST BE CHECKED AS WELL AS LOCAL STRUCTURES (KNEE, ANKLE, FOOT) Poor posture/poor ergonomics are a form of repetitive stress on the upper extremity in addition to typical repetitive stressors Stretching and strengthening is essential for total recovery • GAIT DYSFUNCTION CAUSES REPETITION STRESS INJURY. THE AVERAGE PERSON REPEATS A GAIT CYCLE ONE MILLION TIMES A YEAR Worksite evaluations are very appropriate and helpful. Occupational Therapy is invaluable with many tough cases Ask patient about job, cell phones , keyboarding, mouse, one sided carrying habits • FASCIAS ARE IMPORTANT TO TREAT BECAUSE THEY STORE AND RELEASE ENERGY DYNAMICALLY. FASCIAL DYSFUNCTIONS IN THE LOWER EXTREMITIES WILL GENERATE MULTIPLE PROBLEMS INTO THE TRUNK AND PELVIS Often Cranial/TMJ involvement: Screen with Applied Kinesiology Protocols Breathing patterns– use upper extremity muscle group TMJ Protocol- use upper extremity muscle group LOWER EXTREMITY PEARLS ! LOWER EXTREMITY PEARLS ! • THE KNEE IS A PLACE OF MANY MINOR MOVEMENTS (SLIPPING, EXTERNAL AND INTERNAL ROTATION OF THE TIBIA). VERY FREQUENTLY, A DECREASE IN A MAJOR MOVEMENT COMES FROM RESTRICTIONS OF MINOR MOVEMENTS. • AFTER TRAUMA, THE TISSUES WILL RETAIN THE INJURY PATTERN. INDIRECT SOFT TISSUE TECHNIQUES MUST BE USED TO RESTORE PROPER PROPRIOCEPTION AND FUNCTIONING. REST AND STRENGTHENING IS NEVER ADEQUATE TO RESTORE NORMAL FUNCTION. • KNEE PAIN IS USUALLY CAUSED BY A PROBLEM ABOVE OR BELOW THE KNEE UNLESS THERE WAS DIRECT TRAUMA TO THE KNEE • MOTION TEST ALL FOOT AND ANKLE BONES TO ASSURE THEY ARE DOING THEIR JOBS. PARTICULARLY CALCANEUS, NAVICULAR, CUBOID, TALUS, AND CUNEIFORMS • LONG BONES LIKE THE TIBIA AND FIBULA MUST BE EVALUATED AT BOTH ENDS AS THE TWO ENDS MOVE IN OPPOSITE DIRECTIONS. AN APPARENT ANTERIOR TIBIO-TALUS DISTALLY CAN ACTUALLY BE A POSTERIOR PROXIMAL TIBIA AT THE FEMUR • CAREFULLY CHECK FOR “TRUE” SHORT LEGS VERSUS FUNCTIONAL SHORT LEGS • MANY KNEE, CALF, ANKLE AND FOOT PROBLEMS ARE DUE TO ADRENAL GLAND STRESS OR OTHER VISCERAL-SOMATIC ISSUES 26 37 FUNCTIONAL RELEASE EXERCISE FUNCTIONAL RELEASE EXERCISE A KEY LESION IS CONSIDERED TO BE THAT MOBILE SEGMENT IN THE MIDDLE OF A 3 SEGMENT STACK OF VERTEBRAE THAT BEHAVES EXACTLY THE OPPOSITE OF THE SEGMENTS ABOVE AND BELOW IT. CAREFUL PALPATION WILL REVEAL THAT THE MOTIONS THAT INCREASE TENSION IN THE TISSUES SURROUNDING SEGMENTS ABOVE AND BELOW THE KEY LESION, WILL ACTUALLY DECREASE TENSION IN THE TISSUES ADJACENT TO THE KEY LESION. THIS WILL ALSO BE TRUE OF THE TISSUE RESPONSES TO INHALATION AND EXHALATION. STAND BEHIND YOUR STANDING PATIENT LIGHTLY HOLDING THEIR FOREHEAD WITH YOUR OTHER HAND MAKE SOFT REPEATED POSTERIOR TO ANTERIOR ( PA) GLIDES WITH YOUR THUMB AND FINGERS TOUCHING THE POSTERIOR FACET PLANES OF THE CERVICAL SPINE REGION BEGIN BY SHEARING P-A AT THE OCCIPUT LEVEL AND THEN PROCEED ONE VERTEBRAL LEVEL AT A TIME UNTIL YOU HAVE INDIVIDUALLY APPRECIATED A PA GLIDE AT EACH LEVEL C-0 THROUGH C-7 TREATMENT IS GENERALLY PERFORMED WITH THE PATIENT SUPINE. THE LEVEL OF THE KEY LESION IS TOUCHED BILATERALLY BY THE PRACTITIONER’S RELAXED FINGERTIPS AND THE ELBOWS ARE SUPPORTED IN SUCH A WAY AS TO SUPPORT THE PATIENT’S HEAD. YOU MAY NOTE THAT ONE OR MORE LEVELS SEEM TO PRODUCE MORE RESISTANCE TO THE P-A GLIDE THAN THE LEVEL ABOVE AND BELOW THAT LEVEL THE TREATING HEALTH PROFESSIONAL WILL PASSIVELY INDUCE THE 6 MONITORING MOTIONS WHILE NOTING WHICH DIRECTIONS PRODUCE GREATER OR LESSER TENSIONS IN THE PALPATED TISSUES. THE PATIENT IS ASKED TO INHALE AND EXHALE AS WELL. AGAIN NOTING WHICH PHASE OF RESPIRATION PRODUCES THE GREATEST SOFTENING OF THE TISSUES. YOU MAY ALSO DO THIS PROCEDURE WITH YOUR PATIENT SEATED ONCE YOU HAVE IDENTIFIED A PARTICULAR CERVICAL SPINE LEVEL THAT EXHIBITS MORE RESISTANCE TO P-A GLIDE THAN THE LEVELS ABOVE AND BELOW, YOU WILL FOCUS YOUR PALPATORY SKILLS AND ATTENTION TO COMPARE THE RELATIVE COMPLIANCE VS. RESISTANCE OF THOSE PARTICULAR TISSUES AS THEY RESPOND TO THE MOTIONS YOU WILL INDUCE PASSIVELY. YOU MUST ALSO NOTE HOW THE PATIENT’S TISSUES RESPOND TO INHALATION AND EXHALATION. ONCE ALL MOTIONS HAVE BEEN EVALUATED AND APPRECIATED FOR THOSE THAT PRODUCE THE GREATEST COMPLIANCE VS. RESISTANCE, THE TREATMENT IS PERFORMED BY “STACKING” ALL THE MOVEMENTS THAT INCREASE COMPLIANCE (EASE ) IN THE TISSUES WITH THE PHASE OF RESPIRATION THAT INCREASES COMPLIANCE (EASE) FUNCTIONAL RELEASE EXERCISE TMJ PROTOCOL 1. Find strong muscle (e.g. TFL) 2. Have patient therapy localize the TMJ with thumb and 5th finger opposing each THESE MOTIONS INCLUDE: FLEXION/EXTENSION 3. SIDEBENDING ROTATION ANTERIOR/POSTERIOR GLIDE LATERAL GLIDE 4. TRACTION/COMPRESSION INHALE/EXHALE A SENSE OF RELEASE AND SOFTENING OF THE PALPATED KEY LESION TISSUES WILL BE FELT UPON SUCCESSFUL PERFORMANCE OF THIS PROCEDURE. other, while 2nd, 3rd, and 4th fingers touch jaw joints. Ask patient to: * Bite hard * Open a little * Open wide * Lateralize left * Lateralize right * Extrude jaw * Retrude jaw * Chew slowly (aerobic) * Chew fast (anaerobic) * Swallow * Talk If any procedures described above weaken the patient, have them repeat the action while holding only the left side of jaw alone and then only the right side of jaw. Whichever side they were touching when their muscle weakened, is the involved side. (You may need to change their head position up/down or left/right for this problem to display itself.) RE-EXAMINATION OF THE PREVIOUS ASYMMETRICAL FINDINGS AND PATTERNS SHOULD DEMONSTRATE MARKED IMPROVEMENT THAT NO LONGER PRODUCES PARADOXICAL FINDINGS BETWEEN THE KEY LESION AND THE VERTEBRAL LEVELS THAT ARE ABOVE AND BELOW THAT SEGMENT. TMJ PROTOCOL (continued) 5. There is a specific treatment procedure for each specific pattern of weakness. 6. You may place paper or tongue depressors between their teeth and see if a specific change in vertical dimension changes their bite weakness. For example, if a person weakens when they clench their teeth forcefully, but they no longer weaken when two tongue depressors are placed between their teeth, then they probably need a bite splint that will approximate this correction. In other words, send them to a dentist who does TMJ work. Final note: The above screening procedure helps confirm that there is a problem with the jaw that needs attention. The patient may have already shown signs and symptoms of TMJ problems in the initial history and physical. TMJ Screen: Jaw Clenched Tight – Muscles Tested 27 38 TMJ Screen: Lateralize Jaw to Left-Muscles Tested TMJ Screen: Jaw Opened Wide-Muscles Tested TMJ Screen: Extrude Jaw Muscles Tested TMJ Screen: Lateralize Jaw to Right-Muscles Tested THE “LIST”! Osteopathic Manipulative Medicine! Chiropractic ! Homeopathy! Bach Flower/ Other Flower Essences! Aroma Therapy! EMDR (Eye Movement Desensitization and Reprocessing)! Gyrontonic and Redcord! Prolotherapy! Nutritional/Metabolic: Toxicity, Food/Chemical Sensitivities Endocrine! Hypnotherapy, Biofeedback, Neurofeedback et al! Bioenergetics and other Mind-Body oriented therapies! Rolfing, Hellerwork, Soma Bodywork, Anatomy Trains! Magnets, Crystals, Lasers, and other energy transfer devices! Shamanic Healing and other forms of “Soul Retrieval”! Chinese Medicine! Reiki, Hands of Light, Therapeutic Touch, Polarity Therapy et al! 28 39 The most common finding is adrenal dysfunction: either hyperactivity or exhaustion. Continuous stress on the adrenal system leads to fatigue, depression, idiopathic rashes, paradoxical wakefulness at night, sugar and stimulant cravings, gastrointestinal irritation, weakened ligaments, dialated pupils, orthostatic hypotension, susceptibility to infections, and marked susceptibility to joint injuries.! The hypothalamic-pituitary-adrenal axis is universally stressed and often dysfunctional post-traumatically. Patients need a thorough examination of their endocrine system to determine the extent of abnormal hormonal involvement.! In general, any gland may exhibit posttraumatic dysfunction. The pancreas may become hypo-functioning on an endocrine or exocrine basis. Menstrual irregularity may follow head or back injury. Each case is unique and needs to be evaluated for possible deleterious sequelae.! B-complex vitamins, vitamin C, minerals, ginseng, gotu kola, saspirilla, rehmannia, adrenal glandular products, and selective Chinese herbal formulas can help restore energetic and metabolic balance to the gland. Occasionally, the patient will require physiologic doses of Cortisone (Cortef).! Dr. Fulford said that the goal of the healer is to help the patient find their destiny. To put the patient in touch with what their ultimate purpose was for being on this earth in this lifetime. Once a patient is doing what they were meant to do, everything else begins to fall in place. Sometimes trauma is a gift that leads to an awareness of what is important and what needs to be done.! Chronic inflammation can be treated with an anti-inflammatory diet (Mediterranean diet minus their food sensitivities) along with therapeutic levels of Omega-3 fatty acids, boswellia serrata, tumeric, bromelain, ginger, garlic, devil’s claw, MSM, CoQ10, and alpha lipoic acid.! 29 40 An Integrative/Functional Medicine Approach for a Woman With Chronic Pain and Inflammation 47-year old white female with two year history of chronic pain and other health problems post-motor vehicle accident (MVA) with whiplash. Pain includes: Retro-orbital and temporal headaches, Cervical, mid-thoracic, and lower back pain. Right wrist pain, left patella pain, and jaw tension. ALL THE ABOVE COMPLAINTS BEGAN AFTER MVA CRANIAL •! •! •! •! •! Insomnia •! Anxiety with Depression •! Irregular Periods •! Irritable Bowel •! “Foggy/Dull” Thinking •! Thyroid Goiter with Nodule---Thyroiditis •! Profound Fatigue •! •! •! Petro-Jugular Dislocation Fronto-Sphenoid Compression Lateral Sphenoid Strain Low CRI (Cranial Rhythmic Impulse) TMJ Opening and Closing Click Pterygoid Muscle Spasm (MRI- torn capsule/disc) CERVICAL •! •! •! •! O-A Joint Instability (Hypermobility) MRI-Atrophy of Rectus Capitus Superior Minor Loss of Cervical Lordosis Lateral Disc Bulge C5-C6 Right VISCERAL THORACIC •! Ptosis Left Kidney •! Restricted Mobility and Motility Liver •! Restricted Diaphragm •! Pain in Supraspinous Ligament T4 - T10 •! Weak Tight Rhomboid LUMBAR/ SACRUM/PELVIS •! Upslipped Right Innominate •! Backward Sacral Torsion EXTREMITIES •! •! •! •! Hypermobile Carpal Bones Restricted Right Proximal Radius Tibial Torsion Left Knee Inhibited Vastus Medialis Muscle 30 41 Treatment for Structural Findings: •! •! •! •! •! •! •! •! •! •! •! Pertinent Laboratory Results: •! •! •! •! •! •! •! •! •! •! •! •! •! •! Cranial Osteopathy Cranio-mandibular Dental Appliance Prolotherapy to Hypermobile Areas Myofascial Release Strain and Counterstrain Muscle Energy Technique Functional Release Visceral Manipulation Physical Therapy Core Strengthening Program Gyrotonic, Red Cord, Pilates Positive for Thyroid Peroxidase Ab Elevation Positive for Anti-Thyroglobulin Ab Elevation Elevated a.m. Cortisol (27) [Normal 8-22] Deficient DHEA-S (26) Positive for Anti-gliadin Ab Positive for Tissue Transglutaminase Ab C-reactive Protein Elevated (1.5) [Normal <0.5] Vitamin D Deficiency (25,OH) (17) [Normal >30] Vitamin B12 Low Normal (285) RBC Magnesium Low Normal (1.6) [Normal 1.5-2.5] Positive for ANA 1:320 Speckled Pattern Fasting Glucose (116) [Normal <100] HgA1C 6.0% [Normal 4-6%] Ferritin Low Normal (12) [Normal 10-300] SPECIALTY LAB TESTING Stool Analysis: •! •! •! •! •! Deficient Bifidobacterium, Lactobacillus Increased sIgA Gliadin Markers Increased Cholesterol, Triglycerides Positive for Candida Albicans 3+ Positive for Blastocystis Hominis Spectracell (Intracellular Nutrition Levels) •! Deficiency: Vitamin B-12, Folate, CO-Q10, Carnitine, Vitamin D, L-Glutamine, Glutathione, Magnesium, Zinc, Vitamin C, Glucose-Insulin Dysregulation SPECIALTY LAB TESTING HAIR ANALYSIS (Doctor’s Data) ALCAT: •! Elevated Mercury, Cadmium, Antimony •! Multiple Food/Chemical Sensitivites: Anchovies, apples, onion, turkey, pork, black pepper, mustard, wheat, barley, basil, rosemary, MSG, malvin, yeast, beet sugar, cane sugar, trout, beef, white potato, almond, pecan, vanilla •! Drug Sensitivities: Ibuprofen, penicillin, acetaminophen, aspirin, piroxicam, neomycin •! Multiple Mold Reactions: Alternaria, pullularia, mucor racemosus URINE TOXIC ELEMENTS ANALYSIS •! Elevated Mercury FECAL TOXIC ELEMENTS •! Elevated Mercury 31 42 CHINESE MEDICINE FINDINGS: •! •! •! •! Salient Physical Findings: •! •! •! •! •! •! •! •! •! •! Swollen, flabby tongue with “toothmarked edges” Color of tongue reddish-purple Coating of tongue grey-yellow greasy Hara/Abdominal Diagnosis: –! Tender Alarm Points: Stomach, Gallbladder, Large Intestine, Kidney •! Pulses: –! Deficient: Kidney, Spleen, San Jiao, Heart –! Excess: Gallbladder, Stomach Overweight (increased waistline, buttocks) Weak, under-conditioned lumbar area, increased lordosis Ridged fingernails with some white spots Dry skin, cracked heels Dry hair, slight male pattern balding Puffy dark lower eyelids Eczematous patches in creases of knees/elbows Rubbery goiter with small nodule Pes anserinus tenderness with valgus knees Pronated flat feet Treatment Plan: •! •! •! •! •! •! •! •! •! •! •! •! •! •! •! •! Gluten-Free diet Vitamin D3 First Line Therapy Approach Probiotics Enzyme Replacement with meals Food/Chemical Elimination Supplement Nutritional Deficiencies Mercury Elimination (Metalloclear, Ultra-Clear Renew) EFAs, EPA-DHA Acupuncture Chinese Constitutional Herbs for Spleen Deficiency, Kidney-Adrenal Deficiency Kaprex AI for autoimmune problem Adrenal Support: Herbs, nutrition, lifestyle Parasite, Yeast Treatment with nutraceuticals and prescription drugs, ( if needed) Exercise Mind- Body Activity Reproduced from A MANUAL OF ACUPUNCTURE by Peter Deadman 32 43 Biochemical Individuality Genetic and Environmental Uniqueness Toxic Chemical Exposure Drugs, Alcohol Poor Diet Trauma Radiation Smoking Stress, Negative Emotions Lack of Exercise 198! 33 44 Biochemical Individuality Genetic and Environmental Uniqueness Support healthy biotransformation Decrease oxidative stress intestinal function Improve Cells Reduce inflammatory activity Minimize environmental triggers Functional Detoxification Stress and sleep management Exercise and perspiration Nutritional support and elimination 199! 200 Gastrointestinal health is a critical component in the inflammatory cascade •! Approximately 60%-80% of your immune system is found in the GI tract (MALT/GALT) •! Necessary to identify what should and should not enter the circulatory system † CLINICAL AND VACCINE IMMUNOLOGY, May 2007, p. 485–492 34 45 Immune tissues line your gastrointestinal tract Proper communication between GI and immune tissues is critical for good health Poor Proper GI Barrier diet, dietary toxins andsignals MALT/GALT and pro-inflammatory and beneficial tissuesmicroflora are nutrients in support contribute constanta communication! healthy to inflammation! immune response! !"#$%&'(# Gut Associated Lymphoid Tissues (GALT) Permeability and Damage •! Poor Nutrition •! Bad bacteria •! Yeast •! Toxins Peyer’s Patch, Mesocolic Lymph Nodes Antibodies line the GI tract Toxins )*+$,!*+$# Dietary Signals Immune Cells ines Cytok Nutrients Communication T-lymphocytes Chemokines Antigen Cy to Good bacteria Probiotic Signals kin es B Cell Antibodies GI inflammation may initiate a cascade of events that can increase systemic inflammation Protein s Leaky Gut/ Inflammatory Triggers Localized Inflammatio n Joints, etc. Liver Stress/ Kupffer Cell Activation Toxi Systemic ns Inflammati Scharz B, et al. Intestinal ischemic reperfusion syndrome: pathophysiology, clinical on significance, therapy: Wien Klin Wochenschr1999;111(14):539-48. MALT/ GALT Activation The Six R’s of “Fixing the Middle”" 1. Remove:! Food allergens, parasites, fungal overgrowth, improper bacterial strains, irritants (NSAIDS) 2. Repair:! The mucosa/intestinal lining to reduce "Leaky Gut Syndrome", including goblet cells, mucosal cells, immune cells at the surface linings 3. Replace:! Digestive enzymes and all factors needed for proper digestion and absorption 4. Re-innoculate:! Restore normal, healthy gut ecology with prebiotic and probiotic factors 5. Revitalize:! Chronically blocked pathways with acupuncture 6. Rebalance! 35 46 Direct interaction between immune cells and dietary inputs impact the inflammatory process the 4R Program! •! Lymph nodes in the GI tract allow immune cells triggered in the GI to circulate throughout the body† the 5R Program! •! Transmigration of antigens across the GI barrier may trigger a systemic immune response the 6R Program! † CLINICAL AND VACCINE IMMUNOLOGY, May 2007, p. 485–492 Address GI issues in the Context of the REPLACE 4R Program REMOVE Address GI issues in the Context of the 4R Program REINNOCULATE REPAIR What does your patient need to support the healing of the mucosal barrier? 36 47 Address GI issues in the Context of the REBALANCE 4R Program RELIEF Spleen/Pancreas Spleen/Pancreas !Specialty Testing: •! ALCAT Platinum blood sensitivity test (200 foods and spices, environmental chemicals, food additives, coloring, molds, pharmacoactive substances, and drugs) •! Comprehensive Digestive Stool Analysis & Parasitology, e.g., MetaMetrix GI 2100 Effects Test •! Glucose - Insulin testing •! SpectraCell Comprehensive 5000 (Identifies intracellular nutritional deficiencies) Spleen / Pancreas: Bloating, gas, indigestion, abdominal swelling, nausea, generalized abdominal pain or discomfort, fatigue, aching muscles, tendency to accumulate phlegm, lumps, cysts and tumors, fibroids, insulin resistance, sweet cravings, anxiety, rumination. Spleen / Pancreas Nutraceuticals, Cont’d:! Spleen / Pancreas Diet & Nutrition:! Eat cooked food in a generally low-carbohydrate diet, e.g., South Beach Diet, Zone Diet, etc. Cook with ginger Avoid cold, raw and phlegm-producing foods ! ! !(Dairy products, tofu, etc.)! PRE AND PROBIOTICS! Vitamin D3 - test Vitamin D (25,OH) level, then treat - (2,000 I.U. daily is common) Chlorophyll complex perles! Lactic acid yeast - Saccharomyces boulardii/Bifido Lactis HN019/ Lacto rhamnosus HN001 with meals Spleen / Pancreas - Other Tx Considerations:! Betaine hydrochloride USP - 500 mg per meal Look for Thyroid problems and treat accordingly Eliminate all food and chemical irritants found on ALCAT test Visceral, spinal and cranial manipulation Prebiotics: Fructo-oligosaccharides (FOS), Inulin, whey protein Probiotics: (Bifidobacterium species, Acidophilus, Lactobacillus species, et al) 37 48 Spleen/Pancreas Spleen / Pancreas Nutraceuticals, Cont’d: Small Intestine/Absorption/transformation of food & contributions to digestion Yeast and Parasite control! Berberine Sulfate TriHydrate - 200 mg B.I.D., Coptis, Oregan Grape, Chinese Skullcap, Phellodendron, Ginger, Licorice, Chinese Rhubarb root and rhizome •! Pancreatic enzymes- increased fatty markers in stool, stool floaters, fat soluble vitamin deficiencies (Spectracell & serum testing, ie Vit D, A, E etc) •! Veggie enzymes- patient preference but not as strong, increase dose •! Exocrine vs. endocrine exocrine = enzymes, endocrine=blood sugar Puts fat in the middle (see insulin resistant protocols later in the lecture) Grapefruit Seed Extract - 200 mg daily Pumpkin Seed, Ginger, Barberry root, Oregon Grape, Goldenseal root, Bromelain, Peptidase Oregano oil, Red Thyme oil, Sage Leaf extract, Lemon Balm extract " Read: Overcoming Thyroid Disorders, Second Edition ! ! ! David Brownstein, M.D. ! Spleen/Pancreas Spleen/Pancreas Rules dampness & moisture (mucous formers) fluids thickening cysts, lumps Rules dampness & moisture Fluids thickening (mucous formers) cysts, lumps •! Vitamin D – labs •! Chlorophyl- healing leaky gut, halitosis (bad breath), chronic intestinal inflammation •! Saccaromyces Boulardii- important constituent of all probiotics, protects against C-difficile, prevents antibiotic induced colitis •! Probiotics- anyone who has taken antibiotics, people w/ immune problems •! Prebiotics- works synergistically with probiotics to establish a healthy intestinal population, diarrhea, people who didn’t get better w/only probiotics •! Berberine- unbelievably effective antifungal, antimicrobrial, used as an alternative to antibiotics, kills yeast and bacteria but doesn’t disturb probiotic status as much, food poisoning, treat diarrhea from bad food reactions •! Oregano- yeast overgrowth yeast cleverly adapts & becomes resistant mucous formers, constant phlegm & mucous *Rotation Plan (building up in dose slowly) -Berberine 1st for 2-3 weeks -Oregano 2nd for 2-3 weeks -Artemesia or Cats Claw following for 2-3 weeks Earth Element/Phase: ST-SP (Pancreas)! !Specialty Testing:! •! H. Pylori breath test /antibody tests! •! Heidelberg test (swallowed pH meter to measure acid/pH of stomach! •! Vitamin B12/Methylmalonic acid tests! •! Parietal cell antibody! •! Intrinsic factor antibody! •! Serum Gastrin Level !"#$%"&'%())(*+,-(%.(+/0'#% +0%."&"1(%$023%4"+,(&+#5% ',1(#+,-(%*/"66(&1(#% 38 49 Patients are coming to you for relief from Gastrointestinal health is the gateway to good health or disease •! Gastritis •! Peptic Ulcer Disease •! Diverticulosis •! IBD (Ulcerative Colitis, Crohn's Disease) •! “Functional Disorders”: chronic diarrhea, constipation, bloating, flatulence (symptoms of IBS), nutrient malabsorption and GERD Do You Have The Answers? •! 70% of humans have GI symptoms or disease •! Most sensitive organ where a wide range of insults can lead to dysfunction •! GI dysfunction leads to diverse clinical manifestations •! Normalization of gut function results in improved clinical outcomes across many diverse diseases There’s more… •! Research has shown associations between compromised GI function and conditions as varied as rheumatoid arthritis, asthma, eczema and certain neurological conditions. •! GI dysfunction can underlie many apparently unrelated conditions with symptoms not localized in the GI tract. •! It’s no wonder so many healthcare professionals are “treating the gut” more often in their patients. !"#$%&'(&)*++*,-&.)$%*/0-1&$23$%*$-/$& 1,)$&4*-5&,6&5*7$18#$&3%,9+$):&&&&&&&&&&&& "#$%&;<&)*++*,-&3$,3+$&0%$&=,13*>0+*?$5& $0/=&@$0%&6,%&/0%$&,6&701>%,*->$18-0+& 3%,9+$)1&0-5&>=$&& >,>0+&=$0+>=&/0%$&/,1>1&$2/$$5&& AB<&9*++*,-&0--C0++@:DE& E.)$%*/0-&F,++$7$&,6&G01>%,$->$%,+,7@& GI hyperpermeability may be connected to a variety of systemic conditions Causes of hyperpermeability and dysbiosis •!NSAID use •!Proton pump inhibitors •!Antibiotics •!Poor diet •!Stress •!Pathogenic organisms/infections •! Systemic inflammatory and immune-related symptoms may be caused by macromolecules crossing a “leaky gut” (intestinal hyperpermeability) •! RA, Ankylosing spondylitis, eczema, chronic urticaria, IBD and others •! Dysbiosis can lead to altered immune function, malabsorption problems and inflammation •! Common manifestations include IBS, vitamin B12 deficiency in elderly, Rheumatoid Arthritis 39 50 Add prebiotic fiber to support healthy probiotic bacteria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`:&a3C9&H<<b&"/>&H(:& GC>&[0%%*$%&U1@6C-/8,-&]$051&>,& Z-/%$01$5&R,2*/*>@&0-5&Z-S0))08,- 2--%# ;<*"71 3/4516-0 *='->-= 2--%#3/5( Normal Intestinal Permeability c@3$%3$%)$09*+*>@ "0:5'6-01 7819/-1/1 *069/-6'1 $-./01 Endotoxins Antigens !"#/0?&@@&6-0#&03#=5&A8#4B(#/0/6&(5#&#'&1'&35#& -:#1/40&=/04##5C50(1#(>&(#'&0#/0'%5&15#/0?&@@&6-0D <'>&%E#FG#5(#&=D#"0(5160&=#/1'>5@/'#%5H5%:B1/-0#1803%-@5I# H&(>-H>81/-=-48G#'=/0/'&=#1/40/J'&0'5G#(>5%&H8I#K/50#L=/0# K-'>501'>%MNNNOMMMPMQRISTNUQVD# ; Systemic Inflammation H 40 51 Case ! Study: CASE HISTORY: INITIAL VISIT NOVEMBER 2013 54 Y/O W/M ENGINEER REFERRED BY HIS MASSAGE THERAPIST CHIEF COMPLAINT: MULTIPLE PROBLEMS RESISTANT TO TREATMENT INCLUDING: LONG TERM GERD, THORACIC PAIN T5-T7, WEIGHT LOSS, FATIGUE, LACK OF FOCUS, CHRONIC SORE THROAT, FROZEN SHOULDER, DEPRESSION, INSOMNIA, HEMORRHOIDS, JOINT PAINS SCATTERED ALLERGIES: PCN (HIVES), RAGWEED, DUSTMITES MEDS: WELLBUTRIN XL 300MG, CLARITIN 10MG, PEPCID AC 10MG, AMBIEN 10 MG, DGL prn, LACTASE prn, Whole Foods PROBIOTIC bid Case ! Study: Case ! Study: 41 52 Case ! Study: Case ! Study: Case ! Study: Case ! Study: Case Study: Case ! Study: 42 53 Case ! Study: Liver: Toxicity Issues! Specialty Testing: ! Heavy metal toxic elements (hair, urine, stool, blood) Doctor’s Data, Genova Diet & Nutrition:! Clean up the diet, eliminate refined carbohydrates, hydrogenated oils, all “junk” and fast foods, alcohol, drugs, (unless medically necessary) Increase dietary fiber and pure water intake GallBladder Wood Element/Phase: GB-LR! Fat Malabsorption, food intolerance, migraine headaches, bloating/nausea after eating !Gall Bladder: Headaches, migraines, bloating/ nausea after eating, refractory pain right-sided between shoulder blades or in the shoulder, knee pain w/o orthopedic signs • Vitamin A- Thins bile (sludge bile), thins lymph • Lipotropics- thins bile, aids in production of healthy bile and fat breakdown • Iodine- thins bile Gall Bladder - Nutraceuticals:! Liver Detoxification Overview MYCELIZED A: Vitamin A - (mixed carotenoids and palmitate) 5,000-10,000 I.U. (short term for 7-10 days) then 2,000-3,000 I.U. as maintenance Each person has a specific threshold after which the liver becomes unable to detoxify at a rate capable of preventing symptoms. ! Phase 1 & Phase 2 pathways are critical for removal of toxins, and many nutrients are dependant for each detoxification pathway.! Lipotropics- Choline Bitartrate USP – 500 mg daily, Inositol, Taurine, L-Methionine, Artchoke Leaf, Chen Pi, Betaine HCL, Vit. C, B6, Folate, B12, Mag Detoxification problems can be found in either one or both pathways.! Iodine (Potassium Iodide USP as kelp) - 250-1,000 mcg daily (watch thyroid function) A major issue for liver detoxification is maintaining Glutathione levels.! 43 54 Additional laboratory tests to help you identify elevated toxic burden in your patients! Biochemical Individuality Clinical Importance of the Cytochrome P450 Evens WE and McLeod HL, New Engl J Medicine 2003; 348:548 260 Patients with symptoms of toxicity may have compromised detoxification pathways Toxins from the environment and diet may lead to health challenges in your patients •! Excessive toxic load and poor expression of clearance enzymes and transport proteins may lead to a buildup of toxins in the body •! Continuous exposure to dietary and environmental toxins may lead to an impairment in the ability of patients to metabolize and clear damage causing compounds from their body Supportive Nutrients for Liver Detoxification Pathways 2>&15#"""I#"0'%5&153#B%/0&%8#&=A&=/0/(8#@&8#1BHH-%(### 5.'%56-0#-:#@&08#9/-(%&01:-%@53#(-./01# Neutralized Toxin TOXINS Neutralized Toxin Phase I Functionalization 263! Phase II Conjugation Phase III Alkaline urine supports excretion 44 55 •! Many of your patients’ health challenges are associated with accumulated toxins ! Patients presenting with: –! Generalized muscle aches –! Chronic fatigue –! Fibromyalgia –! Food allergies or chemical sensitivities 266! Major Detoxification Activities in Drug Metabolism From Iarovici (1997) 267! 268 CYP-450 Phase I under-expression: –! Toxins accumulate in adipose tissue –! Rates of metabolism for toxins are compromised –! Exhibits symptoms of toxicity CYP-450 Phase I over-expression: –!Creates more reactive intermediaries than can be neutralized by Phase II enzymes –!Places patients at risk for tissue damage from reactive compounds 270! 269! 45 56 272 “Some patients metabolize ... so rapidly that therapeutically effective blood and tissue concentrations are not achieved; in others, metabolism may be so slow that usual doses produce toxic effects.” Merck Manual Section 22, Chapter298 271! Reduce the amount of incoming toxins –! Elimination diet with a 10- or 28-day protocol Provide nutritional support –! Organic low-allergy-potential protein, medium chain triglycerides, and complex carbohydrates with highly bioavailable vitamins, minerals, and antioxidants Fed Proc. 1986 Feb;45(2):142-8. 273 Nutrient Support for Phase II Detoxification Pathways 274! Liver Detoxification - Nutraceuticals: Phase II Pathways: Detox Medical Foods- ! NAC, Silymarin from Milk thistle, EGCG from Green Tea Extract, Sodium Sulphate, Taurine, Choline, Artichoke Leaf extract, Watercress, Ellagic Acid from Pommegranate, Methylators (B6, B12, Folate, Biotin, B5), Mg, Z, Se, Cu, Mn, Vit A etc ! Sulfation: –! N-acetylcysteine, Sodium Sulfate Acetylation: –! Vitamin B5, Magnesium Methylation: –! Vitamin B12, Choline, 5-MTHF 275 46 57 Liver: Toxicity Issues! Specialty Testing: ! Heavy metal toxic elements (hair, urine, stool, blood) Doctor’s Data, Genova •! “The presence of dietary simple sugars, saturated fats, and salt within an organism may echo its stress experience – an experience assimilated by others when consumed.” •! “As each successive consumer in the food chain incorporates the stress phenotypes of its dietary components, cues for stress may accumulate in a game of “you-are-what-you-eat.” Diet & Nutrition:! Clean up the diet, eliminate refined carbohydrates, hydrogenated oils, all “junk” and fast foods, alcohol, drugs, (unless medically necessary) Increase dietary fiber and pure water intake Yun and Doux, Med Hypotheses 2007; 69:746-751. 278 Turmeric/Curcumin Turmeric (Curcuma longa) roots have long been used as both a food ingredient (spice, coloring agent) and medicinal agent in East Asia. This plant, related to ginger, contains the potent antiinflammatory agent, curcumin, Curcumin is known to be a potent inhibitor of NF-kB, COX-2, LOX as well as many other enzymes within the inflammatory pathway (many regulated through NF-kB). Curcumin also reduces other inflammatory mediators such as IL-6, LL-1ß, MCP-1 and metalloproteinases in animal models.! 279 Reports have confirmed that oral doses of curcumin inhibit the production of COX-2, limiting the formation of PGE2, as well as reducing pro-inflammatory mediators from LOX in animals and humans.! Curcumin is considered to be extremely safe and no toxicity is noted even at high doses.! Plummer SM, et al. Inhibition of cyclo-oxygenase 2 expression in colon cells by the chemoprotective agent cucumin involves inhibition of NF-KappaB activation via NIK/IKK signaling complex. Oncogene 1999 Oct 28;18(44):6013-20.! 47 58