2013 LABORATORY TEST DIRECTORY

Transcription

LABORATORY
TEST DIRECTORY
2013
The printed version of ARUP’s Laboratory Test Directory contains information that is
current as of December 19, 2012. All information contained herein is subject to change.
For current, up-to-date test information, including test-collection specifications, please
view the electronic Laboratory Test Directory on www.aruplab.com.
DECEMBER 2012
The printed version of ARUP’s Laboratory Test Directory contains information that is current as of
December 19, 2012. All information contained herein is subject to change. For current, up-to-date
test information, including test-collection specifications, please view the electronic Laboratory Test
Directory on www.aruplab.com.
0049360
1p/19q Deletion by FISH
1P19Q
Methodology:
Fluorescence in situ Hybridization
Specimen Required: Collect: Tumor tissue.
Specimen Preparation: Formalin fix (10 percent neutral buffered formalin) and paraffin embed tissue. Transport tissue block or 6 unstained 5
micron slides. (Min: 3 slides) Protect paraffin block from excessive heat. Transport block(s) and/or slide(s) in a tissue transport kit (ARUP supply
#47808) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787.
Storage/Transport Temperature: Room temperature or refrigerated. Ship in cooled container during summer months.
Remarks: Include surgical pathology report.
Unacceptable Conditions: Frozen specimens. Specimens fixed or processed in alternative fixatives (alcohol, Prefer®) or heavy metal fixatives (B4 or B-5). No tumor in tissue. Decalcified specimens.
Stability: Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable
CPT Code(s):
88368 x4
0099746
18-Hydroxycorticosterone
18 HYDCORT
Methodology:
High Performance Liquid Chromatography/Tandem Mass Spectrometry
Specimen Required: Collect: Plain red.
Specimen Preparation: Separate serum from cells within 1 hour of draw. Transfer 3 mL serum to an ARUP Standard Transport Tube and freeze
immediately. (Min: 1 mL)
Storage/Transport Temperature: Frozen.
Stability: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 3 months
CPT Code(s):
82542
0010003
ABO Group & Rh Type
Methodology:
Hemagglutination
Specimen Required: Collect: Plain red, lavender (EDTA), or pink (K2EDTA).
Specimen Preparation: Do not freeze red cells.
Transport 7 mL whole blood (plain red). OR 3 mL whole blood (EDTA).
Pediatric: Transport 0.5 mL (10 drops) whole blood.
Storage/Transport Temperature: Refrigerated.
Remarks:
Unacceptable Conditions: Separator tubes.
Stability: Ambient: 72 hours; Refrigerated: 1 week; Frozen: Unacceptable
CPT Code(s):
86900 ABO; 86901 Rh Typing
IRL-ABORH
0010014
ABO-Rh Prenatal
Methodology:
Hemagglutination
Specimen Required: Collect: Lavender (EDTA) or pink (K2EDTA).
Specimen Preparation: Transport 7 mL whole blood. (Min: 3 mL)
Unacceptable Conditions: Frozen specimens.
CPT Code(s):
86900 ABO; 86901 Rh
ABORH-PR
0010025
ABO-Rh Type
ABORH-A
Methodology:
Hemagglutination
Specimen Required: Collect: Testing is limited to the University of Utah Health Sciences Center, Primary Children's Medical Center, and Intermountain Shriners
Hospital (1017) only.
CPT Code(s):
Lavender (EDTA) or pink (K2EDTA).
Specimen Preparation: Do not freeze. Transport 7 mL whole blood. (Min: 3 mL)
Storage/Transport Temperature: Room temperature.
Remarks:
Unacceptable Conditions: Frozen specimens. Separator tubes.
86900 ABO; 86901 Rh Typing
0060245
Acanthamoeba and Naegleria Culture
ACANT
Methodology:
Qualitative Culture/Microscopy
Specimen Required: Collect: Corneal scrapings, vitreous fluid or tissue.
Specimen Preparation: Place corneal scrapings, vitreous fluid, or tissue in 2 mL of Page's amoeba saline (ARUP supply #31917). Available online
through eSupply using ARUP Connect™ or contact Client Services at (800) 522-2787.
Remarks: Specimen source preferred.
Unacceptable Conditions: Specimens in media or preservatives.
Stability: Ambient: 72 hours; Refrigerated: Unacceptable; Frozen: Unacceptable
CPT Code(s):
87081
2002584
Acanthamoeba and Naegleria Culture and Stains, CSF
ACANTCSF
Methodology:
Qualitative Culture/Microscopy/Calcofluor Stain/Giemsa Stain
Specimen Required: Collect: CSF.
Specimen Preparation: Transfer 1 mL CSF to a sterile ARUP Standard Transport Tube (ARUP supply # 43115). Available online through eSupply
using ARUP Connect™ or contact Client Services at (800) 522-2787. (Min: 0.5 mL)
CPT Code(s):
87081 Culture; 87206 Calcofluor Stain; 87207 Giemsa Stain
Page | 1
0090001
Acetaminophen
ACET
Methodology:
Spectrophotometry
Specimen Preparation: Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Unacceptable Conditions: Plasma. Specimens collected in separator tubes, sodium fluoride/potassium oxalate, or sodium citrate anticoagulants.
Stability: After separation from cells: Ambient: 2 weeks; Refrigerated: 2 weeks; Frozen: 45 days
CPT Code(s):
82003
0091533
Acetaminophen and Oxycodone Quantitation, Serum or Plasma
Methodology:
Quantitative Gas Chromatography-Mass Spectrometry/Immunoassay
Specimen Required: Collect: Plain red or lavender (EDTA).
Specimen Preparation: Transfer 4 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 1.9 mL)
Stability: Ambient: 23 days; Refrigerated: 1 month; Frozen: 1 month
CPT Code(s):
83925 Opiates; 82003 Acetaminophen
0091404
Acetaminophen and Oxycodone Quantitation, Whole Blood
Methodology:
Quantitative Gas Chromatography-Mass Spectrometry/High Performance Liquid Chromatography
Specimen Required: Collect: Lavender (EDTA).
Specimen Preparation: Transfer 4 mL whole blood to an ARUP Standard Transport Tube. (Min: 1.6 mL)
CPT Code(s):
83925 Opiates; 82003 Acetaminophen
0091366
Acetazolamide, Serum or Plasma
Methodology:
High Performance Liquid Chromatography
Stability: Ambient: 2 weeks; Refrigerated: 2 weeks; Frozen: 1 year
CPT Code(s):
80299
0091374
Acetazolamide, Urine
Methodology:
Specimen Required: Collect: Random urine.
Specimen Preparation: Transfer 1 mL urine to an ARUP Standard Transport Tube. (Min: 0.2 mL)
Unacceptable Conditions: Room temperature specimens.
Stability: Ambient: Unacceptable; Refrigerated: 2 weeks; Frozen: 1 month
CPT Code(s):
80299
PERCOC SP
PERCOCET B
ACETAZOLAM
ACETAZO U
0090005
Acetone, Quantitative
AC
Methodology:
Quantitative Gas Chromatography
Specimen Required: Collect: Plain red. Also acceptable: Lavender (EDTA), pink (K2EDTA), green (sodium heparin), or gray (sodium fluoride/potassium oxalate).
Avoid use of separator tubes.
Specimen Preparation: Transfer 0.5 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.2 mL)
Stability: After separation from cells: Ambient: 5 days (if tightly capped); Refrigerated: 1 week (if tightly capped); Frozen: 1 month
CPT Code(s):
82010
0091322
Acetophenazine, Serum or Plasma
Methodology:
Specimen Required: Collect: Plain red. Also acceptable: Gray (sodium fluoride/potassium oxalate), green (sodium heparin), or lavender (EDTA).
Specimen Preparation: Protect from light. Transfer 3 mL serum or plasma to an ARUP Amber Transport Tube. (Min: 1.2 mL)
Stability: Ambient: Undetermined; Refrigerated: Undetermined; Frozen: Undetermined
CPT Code(s):
80299
ACETOPHEN
2005639
Methodology:
Acetylcholine Receptor Antibodies and Striated Muscle Antibody Reflexive Panels, and Titin Antibody
MGT R PAN
Quantitative Radioimmunoassay/Semi-Quantitative Radioreceptor Assay/Semi-Quantitative Enzyme-Linked Immunosorbent Assay/SemiQuantitative Indirect Fluorescent Antibody/Semi-Quantitative Flow Cytometry
Specimen Required: Collect: Plain red top or Serum Separator Tube (SST).
Specimen Preparation: Transport 1.5 mL serum. (Min. 0.7 mL) Separate serum from cells ASAP or within one hour of collection. Transfer to an
ARUP Standard Transport Tube.
Storage/Transport Temperature: Refrigerated. Frozen is also acceptable.
Remarks: Repeated freeze-thaw cycles should be avoided.
Unacceptable Conditions: Plasma. Hemolyzed, lipemic, moderately icteric serum or contaminated specimens.
Stability: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year
CPT Code(s):
83519 ACHR Binding Ab; 83519 ACHR Blocking Ab; if reflexed, add 88182TC ACHR Modulating Ab; 83516 TITIN AB; 86255 STM screen; if
reflexed, add 86256 STM titer
2001571
Methodology:
Page | 2
Acetylcholine Receptor Antibody Reflexive Panel
Quantitative Radioimmunoassay/Semi-Quantitative Radioimmunoassay/Semi-Quantitative Flow Cytometry
ACHR R PAN
Specimen Required: Collect: Serum separator tube.
Specimen Preparation: Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport
Tube. (Min: 0.5 mL)
Unacceptable Conditions: Contaminated, hemolyzed, or severely lipemic specimens.
Stability: After separation from cells: Ambient: 2 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
CPT Code(s):
83519 ACHR Binding Ab; 83519 ACHR Blocking Ab; if reflexed, add 88182TC ACHR Modulating Ab
0080009
Acetylcholine Receptor Binding Antibody
ACHRBIN
Methodology:
Quantitative Radioimmunoassay
Specimen Preparation: Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport
Tube. (Min: 0.3 mL)
Unacceptable Conditions: Plasma. Contaminated, hemolyzed, or severely lipemic specimens.
CPT Code(s):
83519
0099580
Acetylcholine Receptor Blocking Antibody
ACHRBLO
Methodology:
Semi-Quantitative Radioimmunoassay
Tube. (Min: 0.5 mL)
CPT Code(s):
83519
0099521
Acetylcholine Receptor Modulating Antibody
ACHRMOD
Methodology:
Semi-Quantitative Flow Cytometry
Tube. (Min: 0.3 mL)
CPT Code(s):
88182TC
2006848
Acetylcholinesterase and Fetal Hemoglobin, Amniotic Fluid
Methodology:
Qualitative Gel Electrophoresis/Radial Immunodiffusion
Specimen Required: Collect: Amniotic Fluid
Specimen Preparation: Transfer 2 mL amniotic fluid to an ARUP Standard Transport Tube. (Min: 1 mL)
Storage/Transport Temperature: Ambient.
Remarks: Include the Amniotic Fluid AFP and MoM results, if available.
Stability: Ambient; 2 weeks; Refrigerated: 4 months; Frozen: 3 years
CPT Code(s):
82013 Acetylcholinesterase; 83033 Fetal Hemoglobin
ACETYL AF
0051266
Achondroplasia (FGFR3) 2 Mutations
AD PCR
Methodology:
Polymerase Chain Reaction/Fluorescence Resonance Energy Transfer
Specimen Required: Collect: Lavender (EDTA), pink (K2EDTA), or yellow (ACD Solution A or B).
Remarks:
Unacceptable Conditions: Serum. Frozen specimens. Hemolyzed specimens.
CPT Code(s):
83891 Isolation; 83898 Amplification; 83896 x2 Nucleic acid probes; 83912 Interpretation and report. Additional CPT code modifiers may be
required for procedures performed to test for oncologic or inherited disorders.
0051265
Achondroplasia (FGFR3) 2 Mutations, Fetal
AD PCR FE
Methodology:
Polymerase Chain Reaction/Fluorescence Monitoring
Specimen Required: Collect: Fetal Specimen: Two T-25 flasks at 80% confluency of cultured amniocytes. If the client is unable to culture amniocytes, this can be
arranged by contacting ARUP Client Services at (800) 522-2787. Or amniotic fluid.
AND Maternal Cell Contamination Specimen: Lavender (EDTA), pink (K2EDTA), or yellow (ACD Solution A or B).
Specimen Preparation: Cultured Amniocytes: Fill flasks with culture media. Transport two T-25 flasks at 80% confluency of cultured
amniocytes. Backup cultures must be retained at the client's institution until testing is complete.
OR Amniotic Fluid: Transport 10 mL unspun fluid. (Min: 5 mL)
AND Maternal Cell Contamination Specimen: Transport 3 mL whole blood. (Min: 1 mL)
Storage/Transport Temperature: Cultured Amniocytes: CRITICAL ROOM TEMPERATURE. Must be received within 48 hours of shipment
due to liability of cells.
Amniotic fluid: Room temperature.
Maternal Cell Contamination Specimen: Room temperature.
Remarks: Maternal specimen is recommended for proper test interpretation. Order Maternal Cell Contamination. Patient History Form
is available on the ARUP Web site or by contacting ARUP Client Services.
Stability: Fetal Specimen: Ambient: 48 hours; Refrigerated: Unacceptable; Frozen: Unacceptable
Maternal Cell Contamination Specimen: Ambient: 72 hours; Refrigerated: 1 week; Frozen: Unacceptable
CPT Code(s):
83891 Isolation; 83898 Amplification; 83896 x2 Nucleic acid probes; 83912 Interpretation and report. FCC: 83900 Multiplex amplification;
83901 x14 Additional amplification; 83909 Capillary electrophoresis. MCC MAT (0050608): 83891 Isolation; 83900 Multiplex amplification;
83901 x14 Additional amplification; 83909 Capillary electrophoresis, 83912 Interpretation and report.
Page | 3
0060325
Acid Fast Stain, Partial or Modified (for Nocardia spp.)
MS PAFS
Methodology:
Stain/Microscopy
Specimen Required: Collect: Aspirate, fluid, respiratory specimen, or tissue.
Specimen Preparation: Transport fluid or aspirate in sterile container. OR Tissue: Place on gauze moistened with sterile non-bacteriostatic saline
to prevent drying and transport in sterile container.
Stability: Ambient: 72 hours; Refrigerated: 72 hours; Frozen: Unacceptable
CPT Code(s):
87206
0049010
Acid Hemolysin (Ham Test)
HAM
Methodology:
Visual Identification
Specimen Required: Collect: Plain red AND lavender (EDTA) or pink (K2EDTA).
Specimen Preparation: Separate serum from cells within 2 hours of collection. Transport 3 mL serum AND 5 mL whole blood. (Min: 1.5 mL
serum AND 1 mL whole blood).
Storage/Transport Temperature: Room temperature. Specimens should be received within 24 hours of collection and testing must be performed
within 48 hours of collection.
Remarks: Indicate patient's blood type on test request form.
Unacceptable Conditions: Serum specimens that have not been separated from the cells within 2 hours of collection.
Stability: After separation from cells: Ambient: 48 hours; Refrigerated: Unacceptable; Frozen: Unacceptable
CPT Code(s):
85475
0020544
Acid Phosphatase, Total, Serum
ACS
Methodology:
Quantitative Enzymatic
Specimen Preparation: Allow specimen to clot completely at room temperature. Transfer 1.5 mL serum to an ARUP Standard Transport Tube.
(Min: 0.5 mL)
Storage/Transport Temperature: CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.
Unacceptable Conditions: Plasma. Non-frozen specimens. Hemolyzed specimens.
Stability: After separation from cells: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 1 month
CPT Code(s):
84060
0060152
Acid-Fast Bacillus (AFB) Culture and AFB Stain
MC AFB
Methodology:
Stain/Culture
Specimen Required: Patient Preparation:
Recommended collection: Three sputum specimens at 8-24 hour intervals (24 hours when possible) and at least one firstmorning specimen. An individual order must be submitted for each specimen.
Collect: Sputum. OR body fluid, CSF, gastric aspirate, tissue, or urine.
Specimen Preparation: Sputum: Transfer (for each collection) 5-10 mL to a sterile container. (Min: 1 mL)
Body Fluids or CSF: Transfer 5 mL to a sterile container. (Min: 1 mL)
Gastric Aspirates: Must be neutralized (pH7) with sodium carbonate if transport is delayed for more than four hours. Transfer 5-10 mL to a
sterile container. (Min: 1 mL)
Tissue: Transfer to a sterile container. (Min: Visible)
Urine: Transfer at least 40 mL to a sterile container. (Min: 10 mL)
Place each specimen in an individual, sealed bag.
Remarks: Specimen source required. Acid fast stain will not be performed on stool specimens, CSF if less than 5 mL, or urine specimens if less
than 40 mL.
Unacceptable Conditions: Dry material or material collected and transported on a swab.
Stability: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 1 week
CPT Code(s):
87116 Culture. CPT codes for identification and susceptibility vary based on method.
0060738
Acid-Fast Bacillus (AFB) Culture and AFB Stain with Reflex to Mycobacterium tuberculosis Amplified Direct
MC AFBR
Detection
Methodology:
Stain/Culture
Patient Preparation:
Three sputum specimens should be collected at 8-24 hour intervals (24 hours when possible) and should include at least
one first-morning specimen. An individual order must be submitted for each specimen.
Specimen Required: Collect: Respiratory specimen.
Specimen Preparation: Transfer (for each collection) 5-10 mL respiratory specimen to a sterile container. (Min: 1 mL) Place each specimen in an
individually sealed bag.
Remarks: Specimen source required.
Unacceptable Conditions: Multiple same-site specimens (more than one in 24 hours), dry material, or material collected and transported on a
swab. Specimens other than respiratory.
Stability: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 2 weeks
CPT Code(s):
87116 Culture. CPT codes for identification and susceptibility vary based on method. If reflexed, add 87556 Amplified probe.
0060999
Methodology:
Acid-Fast Bacillus (AFB) Identification
MC AFBID
Identification
Identification methods may include biochemical, sequencing, nucleic acid probe, or polymerase chain reaction.
Specimen Required: Collect: Actively growing organism, in pure culture.
Specimen Preparation: Transport sealed container with pure culture on solid or in liquid media. Place each specimen in an individually sealed bag.
Storage/Transport Temperature: Room temperature. Submit specimen according to Infectious Substance, Category A, shipping guidelines.
Submit specimen according to Infectious Substance, Category A, shipping guidelines.
Remarks: Indicate source of organism and any other pertinent information, such as the growth rate of the organism or DNA probe results. Probes
can be performed directly from Middlebrook 7H9 broth. MGIT is not
suitable for direct probe testing.
Unacceptable Conditions: Mixed cultures or non-viable organisms. Organisms submitted on an agar plate.
Stability: Ambient: 2 weeks; Refrigerated: 2 weeks; Frozen: 2 weeks
Page | 4
CPT Code(s):
CPT codes for identification vary based on method.
0060997
Acid-Fast Bacillus (AFB) Identification with Reflex to Susceptibility
MC AFBIS
Methodology:
Identification/Susceptibility
Specimen Preparation: Transport sealed container with pure culture on solid or in liquid media. Place each specimen in an individually sealed bag.
Remarks: Indicate source of organism and any other pertinent information such as growth rate of the organism or DNA probe results.
Unacceptable Conditions: Mixed cultures or non-viable organisms. Organisms submitted on agar plate.
CPT Code(s):
CPT codes for identification and susceptibility vary based on method.
0060151
Acid-Fast Bacillus (AFB) Stain Only
MS AFB
Methodology:
Auramine O Stain
Specimen Required: Collect: Sputum or other respiratory specimen.
Specimen Preparation: Transfer 5-10 mL specimen to a sterile container (Min: 1 mL). Place each specimen in an individually sealed bag.
Unacceptable Conditions: Non-respiratory specimens. Swabs from any sites.
Stability: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 2 weeks
CPT Code(s):
87206 Acid-fast stain; 87015 Concentration
2003427
ACTH by Immunohistochemistry
ACTH IHC
Methodology:
Immunohistochemistry
Specimen Required: Collect: Tissue or cells.
Specimen Preparation: Formalin fix (10 percent neutral buffered formalin) and paraffin embed specimen (cells must be prepared into a cellblock).
Protect paraffin block and/or slides from excessive heat. Transport tissue block or 5 unstained (3- to 5-micron thick sections), positively charged
slides in a tissue transport kit (ARUP supply #47808). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services
at (800) 522-2787. (Min: 2 slides). If sending precut slides, do not oven bake.
Remarks: IMMUNOHISTOCHEMISTRY ORDERING AND SUBMISSION DETAILS: Submit electronic request. If you do not have
electronic ordering capability, use an ARUP Immunohistochemistry Stain Form (#32978) with an ARUP client number. For additional technical
details, contact ARUP Client Services at (800) 522-2787.
Unacceptable Conditions: Specimens submitted with non-representative tissue type. Depleted specimens.
Stability: Ambient: Indefinitely, Refrigerated: Indefinitely, Frozen: Unacceptable
CPT Code(s):
88342
0091246
Actifed, Serum or Plasma
ACTIFED SP
Methodology:
Quantitative High Performance Liquid Chromatography/Mass Spectrometry/Gas Chromatography
Specimen Preparation: Separate serum or plasma from cells within 2 hours. Transfer 6 mL serum or plasma to ARUP Standard Transport Tubes.
(Min: 2.6 mL)
CPT Code(s):
82491 Triprolidine; 82542 Pseudoephedrine
2002647
Acute Lymphocytic Leukemia (ALL) Panel by FISH, Adult
FISH A ALL
Methodology:
Specimen Required: Collect: Non-diluted bone marrow aspirate collected in a heparinized syringe. Also acceptable: Whole blood in green (sodium heparin).
Other specimen types may be acceptable, contact the Cytogenetics Laboratory for specific specimen collection and transportation instructions.
Specimen Preparation: Transfer bone marrow to a green (sodium heparin). Transport 3 mL bone marrow OR 5 mL whole blood. (Min: 1 mL bone
marrow OR 2 mL whole blood)
Remarks: If cell pellets or dropped cytogenetics slides are not submitted, a processing fee will apply.
This test must be ordered using Cytogenetic test request form #43099 or through ARUP interface. Submit the Patient History for Cytogenetic
(Chromosome) Studies form with the electronic packing list (available at http://www.aruplab.com/genetics/forms.php).
Unacceptable Conditions: Frozen specimens. Clotted or paraffin-embedded specimens.
CPT Code(s):
88271 x5 DNA probe; 88275 x5 Interphase in situ hybridization 100-300; 88291 Interpretation and report - Additional CPT codes modifiers may
be required for procedures performed to test for oncologic or inherited disorders.
2002719
Acute Lymphocytic Leukemia (ALL) Panel by FISH, Pediatric
FISH P ALL
Methodology:
Specimen Preparation: Transfer bone marrow to a green (sodium heparin). Transport 3 mL bone marrow (Min: 1 mL) OR 5 mL whole blood
(Min: 2 mL).
Remarks: If cell pellets or dropped cytogenetics slides are submitted, a processing fee will not apply.
This test must be ordered using Cytogenetic test request form #43099 or through your ARUP interface.
CPT Code(s):
Page | 5
2002653
Acute Myelogenous Leukemia (AML) with Myelodysplastic Syndrome (MDS) or Therapy-Related AML, by
F TAML MDS
FISH
Methodology:
Specimen Preparation: Transfer bone marrow to a green (sodium heparin). Transport 3 mL bone marrow OR 5 mL whole blood. (Min: 1 mL bone
marrow OR 2 mL whole blood)
Remarks: If cell pellets or dropped cytogenetics slides are submitted, a processing fee will not apply. This test must be ordered using Cytogenetic
test request form (#43099) or through your ARUP interface.
CPT Code(s):
2002384
Acute Myelogenous Leukemia Panel by FISH
FISH AML P
Methodology:
Specimen Preparation: Transfer bone marrow to a green (sodium heparin). Transport 3 mL bone marrow (Min: 1 mL) OR 5 mL whole blood
(Min: 2 mL).
Remarks: If cell pellets or dropped cytogenetics slides are not submitted, a processing fee will apply.
This test must be ordered using Cytogenetic test request form #43099 or through your ARUP interface. Submit the Patient History for Cytogenetic
CPT Code(s):
0091328
Acyclovir, Serum or Plasma
ACYCLOV
Methodology:
Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry
Specimen Required: Collect: Plain red, lavender (EDTA) or Gray (sodium fluoride/potassium oxalate)..
Specimen Preparation: Separate serum or plasma from cells within 2 hours. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube.
(Min: 0.21 mL)
Storage/Transport Temperature: Refrigerated. Also acceptable: Room temperature and frozen.
Stability: Ambient: 1 month; Refrigerated: 1 month; Frozen: 1 month
CPT Code(s):
80299
0091376
Acyclovir, (Zovirax®), Urine
Methodology:
High Performance Liquid Chromatography-Tandem Mass Spectrometry
CPT Code(s):
80299-90
ACYCLOVI U
0040033
Acylcarnitine Quantitative Profile, Plasma
ACYLCARN
Methodology:
Tandem Mass Spectrometry
Specimen Required: Collect: Green (sodium or lithium heparin). Also acceptable: Plain red.
Specimen Preparation: Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum or plasma to an ARUP
Standard Transport Tube and freeze immediately. (Min: 0.2 mL) Avoid hemolysis.
Remarks: Clinical information is needed for appropriate interpretation. Additional required information includes age, gender, diet (eg, TPN
therapy), drug therapy, and family history. Biochemical Genetics Patient History Form is available on the ARUP Web site at
aruplab.com/patienthistory or by contacting ARUP Client Services.
Unacceptable Conditions: Room temperature specimens. Specimens that have been refrigerated for longer than 12 hours.
Stability: After separation from cells: Ambient: Unacceptable; Refrigerated: 12 hours; Frozen: 1 month (avoid repeated freeze/thaw cycles)
CPT Code(s):
82017
0081170
Acylglycines, Quantitative, Urine
ACYLGLY
Methodology:
Liquid Chromatography-Tandem Mass Spectrometry
Specimen Preparation: Transfer 6 mL urine to ARUP Standard Transport Tubes and freeze immediately. (Min: 3 mL) Avoid dilute urine when
possible.
Remarks: Clinical information is needed for appropriate interpretation. Additional required information includes age, gender, diet (e.g., TPN
http://www.aruplab.com/patienthistory or by contacting ARUP Client Services.
Stability: Ambient: Unacceptable; Refrigerated: 24 hours; Frozen: 2 weeks
CPT Code(s):
82544
0030056
ADAMTS13 Activity
ADAMTS-13
Methodology:
Fluorescence Resonance Energy Transfer
Specimen Required: Collect: Lt. blue (sodium citrate). Refer to Specimen Handling at aruplab.com for hemostasis/thrombosis specimen handling guidelines.
Specimen Preparation: Transfer 1 mL platelet-poor plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Page | 6
CPT Code(s):
Unacceptable Conditions: Hemolyzed specimens. Serum or EDTA plasma.
Stability: Ambient: 3 hours; Refrigerated: Unacceptable; Frozen: 2 weeks
85397
2006098
Methodology:
Adenosine Deaminase, CSF
ADA CSF
Quantitative Spectrophotometry
Collect specimens in leak-proof container.
Specimen Required: Collect: Cerebrospinal Fluid.
Specimen Preparation: Centrifuge specimen at room temperature. Transfer 0.3 mL fluid to an ARUP Standard Transport Tube and freeze. (Min:
0.1 mL)
Storage/Transport Temperature: Frozen. Specimen must remain frozen until received in lab.
Remarks: Indicate source on requisition.
Unacceptable Conditions: Whole blood. Bronchoalveolar lavage (BAL) specimens. Turbid specimens.
Stability: Ambient: 2 hours; Refrigerated: 1 week; Frozen: 1 month
CPT Code(s):
84311
2006101
Methodology:
Adenosine Deaminase, Peritoneal Fluid
ADA PERIT
Collect specimens in leak proof container.
Specimen Required: Collect: Peritoneal Fluid.
0.1 mL)
Unacceptable Conditions: Whole blood. Bronchoalveolar Lavage (BAL) specimens. Turbid specimens.
CPT Code(s):
84311
2006096
Methodology:
Adenosine Deaminase, Pleural Fluid
ADA PLEURA
Collect specimens in leak-proof container.
Specimen Required: Collect: Pleural Fluid.
0.1 mL)
Unacceptable Conditions: Whole blood. Bronchoalveolar lavage (BAL) specimens. Turbid specimens.
CPT Code(s):
84311
0083001
Adenosine Deaminase, RBC
Methodology:
Kinetic Spectrophotometry
Specimen Required: Collect: Lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin).
Specimen Preparation: Do not freeze. Transport 1 mL whole blood.
Unacceptable Conditions: Hemolyzed specimens.
Stability: Ambient: 15 days; Refrigerated: 15 days; Frozen: Unacceptable
CPT Code(s):
84311
ADA
0065066
Adenovirus 40-41 Antigens by EIA
ADENO AG
Methodology:
Qualitative Enzyme Immunoassay
Specimen Required: Collect: Stool.
Specimen Preparation: Transfer 5 g stool to an unpreserved stool transport vial (ARUP Supply #40910). Available online through eSupply using
ARUP Connect™ or contact Client Services at (800) 522-2787. (Min: 1 g)
Unacceptable Conditions: Diapers. Specimens in media or preservatives.
Stability: Ambient: 2 hours; Refrigerated: 72 hours; Frozen: 1 week
CPT Code(s):
87301
0051077
Adenovirus Antibodies, IgG & IgM
ADENO PAN
Methodology:
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Tube. (Min: 0.05 mL) Parallel testing is preferred and convalescent samples must be received within 30 days of the acute samples. Mark
specimens plainly as "acute" or "convalescent."
Storage/Transport Temperature: Refrigerated. Also acceptable: Room temperature or frozen.
Unacceptable Conditions: Plasma. Bacterially contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid specimens.
Stability: After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year
CPT Code(s):
86603 x2
0051073
Adenovirus Antibody, IgG
ADENO G
Methodology:
Tube. (Min: 0.05 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days of the acute specimens. Mark
Page | 7
CPT Code(s):
86603
0051078
Adenovirus Antibody, IgM
ADENO M
Methodology:
Tube. (Min: 0.05 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days of the acute specimens. Mark
CPT Code(s):
86603
2003430
Adenovirus by Immunohistochemistry
ADENOV IHC
Methodology:
CPT Code(s):
88342
2002088
Adenovirus DNA, Qualitative, RT-PCR
ADENO QUAL
Methodology:
Real-Time Polymerase Chain Reaction
Specimen Required: Collect: Lavender (EDTA), pink (K2EDTA), yellow (ACD Solution A), plasma preparation tube, or serum separator tube. OR throat,
nasopharyngeal, or eye swabs.
Specimen Preparation: Separate serum or plasma from cells within two hours of collection. Transfer 0.85 mL serum or plasma to an ARUP
Standard Transport Tube. (Min: 0.35 mL) OR transfer swabs to 3 mL viral transport media (Microtest M4 or UTM) (ARUP supply #12884).
Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787.
Storage/Transport Temperature: Refrigerated. Also acceptable: Frozen.
Unacceptable Conditions: Calcium alginate swabs.
Stability: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 1 month (avoid repeated freeze/thaw cycles)
CPT Code(s):
87798
2007192
Adenovirus, Quantitative PCR
ADENO QNT
Methodology:
Quantitative Real-Time Polymerase Chain Reaction
Specimen Required: Collect: Lavender (EDTA), pink (K2EDTA), or serum separator tube
Specimen Preparation: Do not freeze whole blood specimens. Transport 1 mL whole blood, serum or plasma in a sterile container. (Min: 0.5 mL).
Storage/Transport Temperature: Refrigerated
Unacceptable Conditions: Frozen whole blood. Heparinized specimens.
Stability: Ambient: 24 hours; Refrigerated: 5 days; Frozen: 1 year
CPT Code(s):
87799
0070262
Methodology:
Adiponectin
Quantitative Enzyme-Linked Immunosorbent Assay
Patient should fast overnight prior to collection.
Specimen Required: Collect: Plain red or serum separator tube.
Specimen Preparation: Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.1 mL)
Unacceptable Conditions: Specimens from non-fasting patients. Specimens not separated from the red cells. Lipemic specimens.
Stability: After separation from cells: Ambient: 8 hours; Refrigerated: 1 week; Frozen: 1 month
CPT Code(s):
83520
ADIP
0092330
Adrenal Steroid Quantitative Panel by LC-MS/MS, Serum or Plasma
ADSTEROID
Methodology:
Specimen Required: Collect: Serum separator tube. Also acceptable: Plain red, lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin).
Standard Transport Tube and freeze immediately. (Min: 0.25 mL)
Unacceptable Conditions: Refrigerated or room temperature specimens.
Stability: After separation from cells: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 6 months
CPT Code(s):
82634 11-Deoxycortisol; 83498 17-Hydroxyprogesterone; 84143 17-Hydroxypregnenolone; 84140 Pregnenolone
0070010
Adrenocorticotropic Hormone
ACTH
Methodology:
Quantitative Chemiluminescent Immunoassay
Specimen Required: Collect: Lavender (EDTA) or pink (K2EDTA). Collection tube must be siliconized glass or plastic.
Specimen Preparation: Separate plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL plasma to an ARUP Standard Transport
Tube and freeze immediately. (Min: 0.5 mL)
Page | 8
CPT Code(s):
Unacceptable Conditions: Serum, tissue or urine. Heparinized plasma. Grossly hemolyzed or lipemic specimens.
Stability: After separation from cells: Ambient: 24 hours; Refrigerated: 72 hours; Frozen 3 months.
82024
0070031
Methodology:
Adrenocorticotropic Hormone Stimulation, 0 Minutes
CORTISOL 0
Collect 1 timed specimen at 0 minutes.
Specimen Required: Collect: Plasma separator tube or serum separator tube.
Specimen Preparation: Allow specimen to clot completely at room temperature. Separate serum or plasma from cells ASAP or within 2 hours of
collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.4 mL) Specimen must be labeled with time drawn.
Stability: After separation from cells: Ambient: 1 week; Refrigerated: 1 week; Frozen: 3 months
CPT Code(s):
82533
0070032
Methodology:
CORTISOL30
CPT Code(s):
82533
0070033
Methodology:
CORTISOL60
CPT Code(s):
82533
0060115
Methodology:
Aerobic Organism Identification
MC ORG
Identification
Identification methods may include biochemical, mass spectrometry, or sequencing.
Specimen Preparation: Transport sealed container with pure culture on agar slant or on a swab in bacterial transport media. Place each specimen in
an individually sealed bag.
Storage/Transport Temperature: Room temperature. If culture is suspected of being a microorganism listed as infectious substance affecting
humans on IATA list, submit specimen according to Biological Substance, Category A, shipping guidelines.
Remarks: Specimen source required. Indicate suspected pathogen.
Unacceptable Conditions: Mixed cultures or non-viable organisms.
Stability: Ambient: 1 week; Refrigerated: Unacceptable; Frozen: Unacceptable
CPT Code(s):
87077 and/or 87153; CPT codes for identification vary based upon method.
0065070
Methodology:
Aerobic Organism Identification with Reflex to Susceptibility
MC ORGIS
Identification
Identification methods may include biochemical, mass spectrometry, or sequencing.
Specimen Preparation: Transport sealed container with pure culture on agar slant or on a swab in bacterial transport media. Place each specimen in
an individually sealed bag.
Remarks: Specimen source required. Indicate suspected pathogen.
CPT Code(s):
87077 and/or 87153; CPT codes for identification and susceptibility vary based on method.
2006230
Alagille Syndrome (JAG1) by Targeted Sequencing and Deletion/Duplication
JAG1 FGA
Methodology:
Sequencing
Specimen Required: Collect: Whole Blood (EDTA)
Remarks: Do not expose specimen to extreme temperatures. Clinical Indication or Reason for testing is required.
Stability: Ambient: 1 week; Refrigerated: 1 week; Frozen: Unacceptable
CPT Code(s):
83891 Isolation; 83898 x22 Amplification; 83894 x11 Gel separation; 83904 x22 Sequencing; 88386 Array-based evaluation of multiple
molecular probes, 251-500; 83892 x2 Digestion; 83912 Interpretation and report.
0020008
Alanine Aminotransferase, Serum or Plasma
ALT
Methodology:
Specimen Preparation: Allow serum tube to clot completely at room temperature. Separate serum or plasma from cells within 2 hours of
collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.2 mL)
Unacceptable Conditions: Sodium fluoride/potassium oxalate used as an anticoagulant. Hemolyzed specimens. Specimens containing cellular
material.
Page | 9
CPT Code(s):
Stability: After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 1 week
84460
0050024
Albumin, Body Fluid
ALB-BF
Methodology:
Quantitative Nephelometry/Quantitative Spectrophotometry
Specimen Required: Collect: Body fluid.
Specimen Preparation: Centrifuge and separate to remove cellular material. Transfer 1 mL body fluid to an ARUP Standard Transport Tube. (Min:
0.35 mL)
Remarks: Indicate source on the test request form.
Unacceptable Conditions: Contaminated or grossly hemolyzed specimens. Needle sent with specimen.
Stability: After separation from cellular material: Ambient: 8 hours; Refrigerated: 8 days; Frozen: 1 month (avoid repeated freeze/thaw cycles)
CPT Code(s):
82042
0050671
Albumin by Nephelometry
ALB N
Methodology:
Quantitative Nephelometry
Specimen Required: Collect: Serum separator tube. Also acceptable: Green (sodium or lithium heparin).
Specimen Preparation: Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard
Transport Tube. (Min: 0.4 mL)
Unacceptable Conditions: Contaminated or hemolyzed specimens.
Stability: After separation from cells: Ambient: 8 hours; Refrigerated: 8 days; Frozen: 1 year (if frozen within 24 hours)
CPT Code(s):
82040
0050200
Albumin, CSF
ALB CSF
Methodology:
Specimen Preparation: Centrifuge and separate to remove cellular material. Transfer 1 mL CSF to an ARUP Standard Transport Tube. (Min: 0.4
mL)
Unacceptable Conditions: Grossly bloody, contaminated, or hemolyzed specimens.
Stability: Ambient: 8 hours; Refrigerated: 8 days; Frozen: 1 year (if frozen within 24 hours) (avoid repeated freeze/thaw cycles)
CPT Code(s):
82042
0080700
Albumin, Glycated
GLY ALB
Methodology:
Quantitative Boronate Affinity Chromatography/Immunoturbidimetry
Specimen Required: Collect: Serum separator tube, lavender (EDTA), or pink (K2EDTA).
Specimen Preparation: Allow serum specimen to clot completely at room temperature. Transfer 1 mL serum or plasma to an ARUP Standard
Stability: After separation from cells: Ambient: 2 hours; Refrigerated: 8 days; Frozen: 3 months
CPT Code(s):
82985
0020030
Albumin, Serum or Plasma by Spectrophotometry
Methodology:
Specimen Required: Collect: Serum separator tube or plasma separator tube.
Stability: After separation from cells: Ambient: 1 week; Refrigerated: 5 months; Frozen: 6 months
CPT Code(s):
82040
ALB
0091312
Albuterol, Serum or Plasma
ALBUTEROL
Methodology:
Quantitative High Performance Liquid Chromatography/Tandem Mass Spectrometry
Specimen Required: Collect: Plain red. Also acceptable: gray (sodium fluoride/potassium oxalate), green (sodium heparin), or lavender (EDTA) or pink (K2EDTA).
(Min: 1.2 mL)
CPT Code(s):
80299
0090131
Methodology:
Alcohols
ALCT
For medical purposes only.
Specimen Required: Collect: Plain red. Also acceptable: Lavender (EDTA), pink (K2EDTA), or gray (sodium fluoride/potassium oxalate).
Specimen Preparation: Do not freeze whole blood. Separate serum from cells within two hours of collection. Transfer 2 mL serum or plasma to a
tightly-capped tube to minimize alcohol loss. (Min: 0.3 mL) Specimens collected in gray (sodium fluoride/potassium oxalate) may be transported
in the original container.
Stability: After separation from cells: Ambient: 1 week (if tightly capped); Refrigerated: 2 weeks (if tightly capped); Frozen: 1 month (except
whole blood)
CPT Code(s):
84600
0020012
Aldolase, Serum
Methodology:
Page | 10
ALDOLASE
CPT Code(s):
Specimen Preparation: Allow specimen to clot completely at room temperature. Transfer 1 mL serum to an ARUP Standard Transport Tube.
(Min: 0.5 mL)
Unacceptable Conditions: Specimen types other than serum. Hemolyzed specimens.
82085
0070016
Methodology:
Aldosterone 30 Minute
If upright specimen is collected, patient should be seated or standing for at least 2 hours.
Specimen Required: Collect: Serum separator tube or plain red.
Specimen Preparation: Transport 1 mL serum. (Min: 0.45 mL) Also acceptable: Heparinized plasma.
Unacceptable Conditions: EDTA plasma.
CPT Code(s):
82088
ALDO 30
0070017
Methodology:
ALDO 60
Aldosterone 60 Minute
Specimen Preparation: Transport 1 mL serum. (Min: 0.45 mL) Also acceptable: Heparinized plasma.
CPT Code(s):
82088
2002582
Methodology:
Aldosterone & Renin, Direct with Ratio
A/DR
Quantitative Radioimmunoassay/Quantitative Immunoradiometry
Supine: 1. Both specimens should be obtained between 8 a.m. and 10 a.m. (after at least two hours in supine position); 2.
Normal sodium diet (100-200 mEq/day) for at least three days; 3. Receiving no medications known to affect renin-aldosterone system.
Upright: 1. Both specimens should be obtained before noon (after at least two hours in upright position; seated or standing). 2. Normal sodium
diet (100-200 mEq/day) for at least three days. 3. Receiving no medications known to affect renin-aldosterone system.
Contact Medical Director if more information is needed.
Specimen Required: Collect: Serum separator tube or green (sodium or lithium heparin) AND lavender (EDTA) or pink (K2EDTA). Do not collect in refrigerated
tubes.
Specimen Preparation: Separate from cells ASAP. Transfer 1 mL serum or heparinized plasma AND 2 mL EDTA plasma to individual ARUP
Standard Transport Tubes and freeze immediately. (Min: 0.5 mL serum or heparinized plasma AND 1 mL EDTA plasma)
Storage/Transport Temperature: CRITICAL FROZEN. Separate specimens must be submitted when additional tests are ordered.
Unacceptable Conditions: Refrigerated plasma. Hemolyzed specimens.
Stability: After separation from cells: Ambient: 4 hours; Refrigerated: Unacceptable; Frozen: 1 month
CPT Code(s):
82088 Aldosterone; 84244 Renin, Direct
0070073
Methodology:
Aldosterone/Renin Activity Ratio
A/RA
Supine: 1. Both specimens should be obtained between 8 a.m. and 10 a.m. (after at least two hours in supine position); 2.
Normal sodium diet (100-200 mEq/day) for at least three days; 3. Receiving no medications known to affect renin-aldosterone system.
Upright: 1. Both specimens should be obtained before noon (after at least two hours in upright position, seated or standing); 2. Normal sodium
diet (100-200 mEq/day) for at least three days; 3. Receiving no medications known to affect renin-aldosterone system.
Contact Medical Director if more information is needed.
Specimen Required: Collect: From either a supine or upright patient, serum separator tube or green (sodium or lithium heparin) AND lavender (EDTA) or pink
(K2EDTA). Do not collect in refrigerated tubes.
Specimen Preparation: Separate from cells ASAP. Transfer 1 mL serum or heparinized plasma AND 2 mL EDTA plasma to individual ARUP
Standard Transport Tubes and freeze immediately. (Min: 0.5 mL serum or heparinized plasma AND 1.2 mL EDTA plasma)
Storage/Transport Temperature: CRITICAL FROZEN. Separate specimens must be submitted when additional tests are ordered.
Unacceptable Conditions: Refrigerated plasma. Hemolyzed specimens.
CPT Code(s):
82088 Aldosterone, 84244 Renin activity
0070015
Methodology:
Aldosterone, Serum
ALDOST
Specimen Preparation: Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) Also acceptable: Heparinized plasma.
CPT Code(s):
82088
Page | 11
0070480
Aldosterone, Urine
ALDO U
Methodology:
Specimen Required: Collect: 24-hour urine. Urine must be refrigerated during collection.
Specimen Preparation: Add 1 g boric acid per 100 mL urine. Transfer 4 mL aliquot of urine from a 24-hour collection to an ARUP Standard
Transport Tube. (Min: 0.5 mL) Record total volume and collection time interval on transport tube and test request form. Also acceptable:
Preserved urine if the pH of the specimen is adjusted to 2-4 with 6M HCl or 50 percent acetic acid or unpreserved urine if frozen immediately
after collection.
Storage/Transport Temperature: Frozen. Also acceptable: Refrigerated, if preserved with HCl or acetic acid.
Stability: Ambient: 2 hours; Refrigerated (with preservative): 1 week; Frozen: 1 month
CPT Code(s):
82088
2006102
ALK Gene Rearrangements in NSCLC for Crizotinib Eligibility by FISH
ALK GENE
Methodology:
Specimen Preparation: Formalin fix (10 percent neutral buffered formalin) and paraffin embed tumor tissue. Transport tissue block or 4 unstained,
consecutively cut, 5-micron thick sections, mounted on positively charged glass slides. (Min: 4 slides) Protect paraffin block and/or slides from
excessive heat.
Storage/Transport Temperature: Room temperature. Also acceptable: Refrigerated.
Remarks: Include surgical pathology report with reason for referral. The laboratory will not reject specimens that arrive without a pathology report
but will hold the specimen until this information is received.
CPT Code(s):
88271 x2 DNA probe each, 88274 Interphase in situ hybridization 25-99 each; 88291 Interpretation and report
2005736
Alkaline Phosphatase Isoenzymes, CSF
CSF ALKP I
Methodology:
Quantitative Heat Inactivation/Enzymatic
Specimen Preparation: Transfer 2 mL CSF to an ARUP Standard Transport Tube and refrigerate or freeze ASAP or within 2 hours. (Min: 1 mL)
Storage/Transport Temperature: Refrigerated or frozen.
Unacceptable Conditions: Specimens collected in EDTA, potassium oxalate, or sodium fluoride. Grossly hemolyzed or lipemic specimens
CPT Code(s):
84075 ALKP total; 84080 ALKP isoenzymes
0021020
Alkaline Phosphatase Isoenzymes, Serum or Plasma
ALKP-ISO
Methodology:
Quantitative Heat Inactivation/Enzymatic
Specimen Required: Collect: Serum separator tube or green (sodium or lithium heparin).
Specimen Preparation: Allow serum specimen to clot completely at room temperature. Separate serum or plasma from cells ASAP or within 2
hours of collection. Transfer 2 mL serum or plasma to an ARUP Standard Transport Tube and refrigerate or freeze immediately. (Min: 1 mL)
Unacceptable Conditions: Specimens collected in EDTA, sodium fluoride, or potassium oxalate. Grossly hemolyzed or lipemic specimens.
Stability: After separation from cells: Ambient: 1 hour; Refrigerated: 1 week (total activity will increase 2 percent per day); Frozen: 1 year
CPT Code(s):
84075 ALKP total; 84080 ALKP isoenzymes
0020005
Alkaline Phosphatase, Serum or Plasma
ALKP
Methodology:
Unacceptable Conditions: Specimens collected in EDTA or sodium fluoride/potassium oxalate. Grossly hemolyzed specimens.
CPT Code(s):
84075
0055421
Methodology:
Allergen, Drugs, Amoxicillin
AMOXICIL
Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay
Multiple patient encounters should be avoided.
Specimen Required: Collect: Serum separator tube. Multiple specimen tubes should be avoided.
Specimen Preparation: Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.25 mL serum plus 0.1 mL for each additional
allergen ordered to an ARUP Standard Transport Tube. (Min: 0.25 mL plus 0.04 mL for each allergen ordered)
Unacceptable Conditions: Hemolyzed, icteric, or lipemic specimens.
CPT Code(s):
86003
0055422
Methodology:
Allergen, Drugs, Ampicillin
AMPICIL
CPT Code(s):
86003
0099628
Methodology:
Allergen, Drugs, Penicillin G (major)
Page | 12
PENICIL G
CPT Code(s):
86003
0099629
Methodology:
Allergen, Drugs, Penicillin V (minor)
PENICIL V
CPT Code(s):
86003
0099635
Allergen, Epidermals and Animal Proteins, Australian Parrot Droppings IgE
Methodology:
Specimen Preparation: Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL/allergen)
Storage/Transport Temperature: Room temperature. Also acceptable: Refrigerated or frozen.
Stability: Ambient: 1 month; Refrigerated: 1 month; Frozen: 1 year
CPT Code(s):
86003
PARROT DRP
0099714
Methodology:
Allergen, Epidermals & Animal Proteins, Budgerigar Droppings (Parakeet)
PARA DROP
CPT Code(s):
86003
0055006
Methodology:
Allergen, Epidermals & Animal Proteins, Cat Dander
CATEPI
CPT Code(s):
86003
0055378
Methodology:
Allergen, Epidermals & Animal Proteins, Chicken Feathers
CHICKFEATH
CPT Code(s):
86003
0055044
Methodology:
Allergen, Epidermals & Animal Proteins, Cow Hair & Dander
COW H/D
CPT Code(s):
86003
0099568
Methodology:
Allergen, Epidermals & Animal Proteins, Dog Dander
DOG DANDER
Page | 13
CPT Code(s):
86003
2003300
Methodology:
Allergen, Epidermals and Animal Proteins, Duck Feathers IgE
DUCKFEATH
Specimen Required: Collect: Serum separator tube.Multiple specimen tubes should be avoided.
CPT Code(s):
86003
0055037
Methodology:
Allergen, Epidermals and Animal Proteins, Feather Mix
FEATHER
Qualitative ImmunoCAP® Fluorescent Enzyme Immunoassay
CPT Code(s):
86003
0055188
Methodology:
Allergen, Epidermals and Animal Proteins, Goat Epithelium IgE
GOAT EPI
CPT Code(s):
86003
0055177
Methodology:
Allergen, Epidermals & Animal Proteins, Goose Feathers
GOOSE FEAT
CPT Code(s):
86003
0055190
Methodology:
Allergen, Epidermals and Animal Proteins, Guinea Pig Epithelium IgE
G PIG EPI
CPT Code(s):
86003
0055189
Methodology:
Allergen, Epidermals & Animal Proteins, Hamster Epithelium
HAMPST EPI
CPT Code(s):
86003
0055059
Methodology:
Allergen, Epidermals & Animal Proteins, Horse Hair & Dander
HORSE
Page | 14
CPT Code(s):
86003
0055191
Methodology:
Allergen, Epidermals & Animal Proteins, Mouse Epithelium
MOUSE EPI
CPT Code(s):
86003
0055192
Methodology:
Allergen, Epidermals and Animal Proteins, Mouse Urine IgE
MOUSE U
CPT Code(s):
86003
0055193
Methodology:
Allergen, Epidermals & Animal Proteins, Parakeet Feathers (Budgerigar)
PARAK FTHR
CPT Code(s):
86003
0055195
Methodology:
Allergen, Epidermals and Animal Proteins, Pig (Swine) Epithelium IgE
PIG EPI
CPT Code(s):
86003
0055196
Methodology:
Allergen, Epidermals and Animal Proteins, Pigeon Stools IgE
PIGEON STL
CPT Code(s):
86003
0099544
Methodology:
Allergen, Epidermals & Animal Proteins, Rabbit Epithelium
RABBIT EPI
CPT Code(s):
86003
Page | 15
0055197
Methodology:
Allergen, Epidermals and Animal Proteins, Rat Epithelium IgE
RAT EPI
CPT Code(s):
86003
0055198
Methodology:
Allergen, Epidermals and Animal Proteins, Rat Urine IgE
RAT URINE
CPT Code(s):
86003
0055199
Methodology:
Allergen, Epidermals & Animal Proteins, Sheep Epithelium/Wool
SHEEP EPI
CPT Code(s):
86003
0099577
Methodology:
Allergen, Food, Almond
ALMOND
CPT Code(s):
86003
0090284
Allergen, Food, Almond IgG
ALMOND IGG
Methodology:
Specimen Required: Collect: Serum separator tube (SST).
Tube. (Min: 0.2 mL/allergen)
CPT Code(s):
86001
0099543
Methodology:
Allergen, Food, Alpha-Lactalbumin
ALPHA-LACT
CPT Code(s):
86003
0093498
Allergen, Food, Anchovy IgE
Methodology:
CPT Code(s):
86003
0099632
Methodology:
Page | 16
Allergen, Food, Apple
ANCHOVY
APPLE
CPT Code(s):
86003
0055423
Methodology:
Allergen, Food, Apricot
APRICOT
CPT Code(s):
86003
2007179
Allergen, Food, Artichoke IgE
Methodology:
Quantitative Conventional RAST
CPT Code(s):
86003
ARTI IGE
0098873
Methodology:
Allergen, Food, Asparagus IgE
ASPARAGUS
CPT Code(s):
86003
0099695
Methodology:
Allergen, Food, Avocado
AVOCADO
CPT Code(s):
86003
0055079
Methodology:
Allergen, Food, Baker's Yeast/Brewer's Yeast
BAKE YEAST
CPT Code(s):
86003
0097706
Allergen, Food, Baker's Yeast IgG
YEAST IGG
Methodology:
CPT Code(s):
86001
0099634
Methodology:
Allergen, Food, Banana
BANANA
Page | 17
CPT Code(s):
86003
0090286
Allergen, Food, Banana IgG
BANANA IGG
Methodology:
CPT Code(s):
86001
0055056
Methodology:
Allergen, Food, Barley
BARLEY
CPT Code(s):
86003
0097707
Allergen, Food, Barley IgG
BARLEY IGG
Methodology:
CPT Code(s):
86001
0093496
Methodology:
Allergen, Food, Basil IgE
BASIL
CPT Code(s):
86003
0099692
Allergen, Food, Bass Black IgE
Methodology:
CPT Code(s):
86003
BASS
0093494
Methodology:
Allergen, Food, Bay Leaf IgE
BAY LEAF
CPT Code(s):
86003
0055096
Methodology:
Allergen, Food, Beef
BEEF
CPT Code(s):
86003
Page | 18
0097708
Allergen, Food, Beef IgG
BEEF IGG
Methodology:
CPT Code(s):
86001
2006689
Methodology:
Allergen, Food, Beet Root IgE
BEET ROOT
CPT Code(s):
86003
0055074
Methodology:
Allergen, Food, Beta-Lactoglobulin
BETA-LACT
CPT Code(s):
86003
0055214
Allergen, Food, Black Olive IgG
Methodology:
Stability: Ambient: 1 week; Refrigerated: 1 month; Frozen: 1 year
CPT Code(s):
86001
OLIVE
0055424
Methodology:
Allergen, Food, Black Pepper
BK PEPPER
CPT Code(s):
86003
0055425
Methodology:
Allergen, Food, Blue Mussel
MUSSEL
CPT Code(s):
86003
0055426
Methodology:
Allergen, Food, Blueberry
BLUEBERRY
CPT Code(s):
86003
0099574
Methodology:
Page | 19
Allergen, Food, Brazil Nut
BRAZIL NUT
CPT Code(s):
86003
0098531
Methodology:
Allergen, Food, Broccoli
BROCCOLI
CPT Code(s):
86003
0092597
Methodology:
Allergen, Food, Buckwheat IgE (Fagopyrum esculentum)
BUCKWH IGE
Tube.
Unacceptable Conditions: Hemolyzed, icteric or lipemic specimens.
CPT Code(s):
86003
0055094
Methodology:
Allergen, Food, Cabbage
CABBAGE
CPT Code(s):
86003
2001903
Allergen, Food, Caraway Seed IgE
Methodology:
CPT Code(s):
86003
CARAWAY
2001905
Allergen, Food, Cardamom Seed IgE
Methodology:
CPT Code(s):
86003
CARD SEED
2001907
Allergen, Food, Carob Gum/Locust Bean IgE
Methodology:
CPT Code(s):
86003
CAROB GUM
0055005
Methodology:
Allergen, Food, Carrot
CARROT
CPT Code(s):
86003
Page | 20
0055081
Methodology:
Allergen, Food, Casein
CASEIN
CPT Code(s):
86003
0097653
Allergen, Food, Casein (Cow's Milk) IgG
CASEIN IGG
Methodology:
CPT Code(s):
86001
0099573
Methodology:
Allergen, Food, Cashew
CASHEW
CPT Code(s):
86003
0097629
Methodology:
Allergen, Food, Catfish IgE
CATFISH
CPT Code(s):
86003
0099054
Methodology:
Allergen, Food, Celery
CELERY
CPT Code(s):
86003
0099583
Methodology:
Allergen, Food, Cheese, Cheddar
CHEDDAR
CPT Code(s):
86003
0099593
Methodology:
Allergen, Food, Cheese Mold
CHEESEMOLD
CPT Code(s):
86003
Page | 21
0099466
Methodology:
Allergen, Food, Cherry IgE
CHERRY
CPT Code(s):
86003
0055254
Methodology:
Allergen, Food, Chestnut
CHESTNU
CPT Code(s):
86003
0055008
Methodology:
Allergen, Food, Chicken
CHICK
CPT Code(s):
86003
0097656
Allergen, Food, Chicken IgG
CHICK IGG
Methodology:
CPT Code(s):
86001
0055200
Methodology:
Allergen, Food, Chickpea (Garbanzo Bean)
CHICKPEA
CPT Code(s):
86003
0099642
Methodology:
Allergen, Food, Chocolate
CHOCOLATE
CPT Code(s):
86003
0097657
Allergen, Food, Chocolate IgG
CHOCO IGG
Methodology:
CPT Code(s):
86001
0098876
Methodology:
Page | 22
Allergen, Food, Cinnamon
CINNAMON
CPT Code(s):
86003
0099488
Methodology:
Allergen, Food, Clam
CLAM
CPT Code(s):
86003
0098875
Allergen, Food, Clove IgE
Methodology:
CPT Code(s):
86003
CLOVE
0099473
Methodology:
Allergen, Food, Coconut
COCONUT
CPT Code(s):
86003
0055036
Methodology:
Allergen, Food, Codfish IgE
COD
CPT Code(s):
86003
0099757
Methodology:
Allergen, Food, Coffee
COFFEE
CPT Code(s):
86003
0097302
Allergen, Food, Coffee IgG
COFFEE IGG
Methodology:
CPT Code(s):
86001
0055078
Methodology:
Allergen, Food, Corn
CORN
Page | 23
CPT Code(s):
86003
0097658
Allergen, Food, Corn IgG
CORN IGG
Methodology:
CPT Code(s):
86001
0055011
Methodology:
Allergen, Food, Crab
CRAB
CPT Code(s):
86003
0098874
Allergen, Food, Cranberry IgE
Methodology:
CPT Code(s):
86003
CRANBERRY
0097637
Methodology:
Allergen, Food, Crayfish IgE
CRAY IGE
CPT Code(s):
86003
0098868
Methodology:
Allergen, Food, Cucumber IgE
CUCUMBER
CPT Code(s):
86003
2001909
Allergen, Food, Currant Red, IgE
CURRANT
Methodology:
Specimen Preparation: Separate serum from cells within 10 minutes. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5
mL/allergen)
CPT Code(s):
86003
0093492
Methodology:
Allergen, Food, Dill IgE
DILL
CPT Code(s):
86003
Page | 24
0097639
Allergen, Food, Eel IgE
Methodology:
CPT Code(s):
86003
EEL IGE
0055013
Methodology:
Allergen, Food, Egg White
EGG
CPT Code(s):
86003
0097659
Allergen, Food, Egg White IgG
EGG IGG
Methodology:
CPT Code(s):
86001
0055381
Methodology:
Allergen, Food, Egg Whole
EGGWHOLE
CPT Code(s):
86003
0055212
Methodology:
Allergen, Food, Egg Yolk
EGG YOLK
CPT Code(s):
86003
0097315
Allergen, Food, Egg Yolk IgG
EGGYOLKIGG
Methodology:
CPT Code(s):
86001
0055432
Methodology:
Allergen, Food, Eggplant
EGGPLANT
CPT Code(s):
86003
0093490
Allergen, Food, Fennel, Fresh IgE
Methodology:
Page | 25
FENNEL FR
CPT Code(s):
86003
2003298
Allergen, Food, Flaxseed/Linseed IgE
Methodology:
CPT Code(s):
86003
FLAX
0099739
Methodology:
Allergen, Food, Flounder (Plaice)
FLOUNDER
CPT Code(s):
86003
0099479
Methodology:
Allergen, Food, Garlic
GARLIC
CPT Code(s):
86003
0090287
Allergen, Food, Garlic IgG
GARLIC IGG
Methodology:
CPT Code(s):
86001
2001911
Methodology:
Allergen, Food, Gelatin Bovine IgE
GEL BOVINE
CPT Code(s):
86003
2001913
Allergen, Food, Gelatin Porcine IgE
Methodology:
CPT Code(s):
86003
GEL PORC
0098865
Methodology:
Allergen, Food, Ginger IgE
GINGER
CPT Code(s):
86003
0099569
Methodology:
Page | 26
Allergen, Food, Gluten
GLUTEN
CPT Code(s):
86003
0090289
Allergen, Food, Gluten IgG
GLUTEN IGG
Methodology:
CPT Code(s):
86001
0055015
Methodology:
Allergen, Food, Grape
GRAPE
CPT Code(s):
86003
0099641
Methodology:
Allergen, Food, Grapefruit
GRAPEFRUIT
CPT Code(s):
86003
0099649
Methodology:
Allergen, Food, Green Bean (String)
STRINGBEAN
CPT Code(s):
86003
2001917
Allergen, Food, Gum Guar IgE
Methodology:
CPT Code(s):
86003
GUM GUAR
0098864
Methodology:
Allergen, Food, Haddock IgE
HADDOCK
CPT Code(s):
86003
0098516
Methodology:
Allergen, Food, Halibut
HALIBUT
Page | 27
CPT Code(s):
86003
0098617
Methodology:
Allergen, Food, Hazelnut (Filbert)
HAZELNUT
CPT Code(s):
86003
0097631
Methodology:
Allergen, Food, Herring IgE
HERRIN IGE
CPT Code(s):
86003
0055435
Methodology:
Allergen, Food, Honeydew Melon/Cantaloupe
HONEY DEW
CPT Code(s):
86003
0055436
Methodology:
Allergen, Food, Hops
HOPS
CPT Code(s):
86003
0055440
Methodology:
Allergen, Food, Kidney Bean
KIDNEYBEAN
CPT Code(s):
86003
0055203
Methodology:
Allergen, Food, Kiwi
KIWI
CPT Code(s):
86003
0099631
Methodology:
Allergen, Food, Lamb
LAMB
Page | 28
CPT Code(s):
86003
0098270
Methodology:
Allergen, Food, Lemon
LEMON
CPT Code(s):
86003
0099659
Methodology:
Allergen, Food, Lentil
LENTIL
CPT Code(s):
86003
0055019
Methodology:
Allergen, Food, Lettuce
LETTUCE
CPT Code(s):
86003
0097651
Allergen, Food, Lettuce IgG
LETT IGG
Methodology:
CPT Code(s):
86001
0099766
Methodology:
Allergen, Food, Lima Bean/White Bean
LIMA BEAN
CPT Code(s):
86003
0098271
Methodology:
Allergen, Food, Lime
LIME
CPT Code(s):
86003
Page | 29
0099062
Methodology:
Allergen, Food, Lobster
LOBSTER
CPT Code(s):
86003
0093246
Methodology:
Allergen, Food, Macadamia Nut IgE
MACADA NUT
CPT Code(s):
86003
0098474
Methodology:
Allergen, Food, Mackerel
MACKEREL
CPT Code(s):
86003
0099744
Methodology:
Allergen, Food, Malt
MALT
CPT Code(s):
86003
0097652
Allergen, Food, Malt IgG
MALT IGG
Methodology:
Specimen Required: Collect: Collect: Serum separator tube (SST).
CPT Code(s):
86001
0055204
Methodology:
Allergen, Food, Mango
MANGO
CPT Code(s):
86003
0055020
Methodology:
Allergen, Food, Milk (Cow's)
MILK
CPT Code(s):
86003
Page | 30
0099770
Methodology:
Allergen, Food, Mushroom
MUSHROOM
CPT Code(s):
86003
0097299
Allergen, Food, Mushroom IgG
MUSH IGG
Methodology:
CPT Code(s):
86001
0055443
Methodology:
Allergen, Food, Mustard
MUSTARD
CPT Code(s):
86003
0055022
Methodology:
Allergen, Food, Navy Bean
NAVY
CPT Code(s):
86003
0093502
Allergen, Food, Nutmeg IgE
Methodology:
CPT Code(s):
86003
NUTMEG
0055040
Methodology:
Allergen, Food, Oat
OAT
CPT Code(s):
86003
0097654
Allergen, Food, Oat IgG
OAT IGG
Methodology:
CPT Code(s):
86001
2001919
Methodology:
Allergen, Food, Octopus IgE
Page | 31
OCTOPUS
CPT Code(s):
86003
0099474
Methodology:
Allergen, Food, Onion
ONION
CPT Code(s):
86003
0097306
Allergen, Food, Onion IgG
ONION IGG
Methodology:
CPT Code(s):
86001
0055023
Methodology:
Allergen, Food, Orange
ORANGE
CPT Code(s):
86003
0097647
Allergen, Food, Orange IgG
ORANGE IGG
Methodology:
Specimen Required: Collect: Collect: Serum separator tube (SST).
CPT Code(s):
86001
0093500
Methodology:
Allergen, Food, Oregano IgE
OREGANO
CPT Code(s):
86003
0098862
Allergen, Food, Orris Root IgE
Methodology:
CPT Code(s):
86003
Page | 32
ORRIS
2006436
Methodology:
Allergen, Food, Ovalbumin IgE
OVALBUMIN
CPT Code(s):
86003
2006434
Methodology:
Allergen, Food, Ovomucoid IgE
OVOMUCOID
Remarks: N/A
CPT Code(s):
86003
0099638
Methodology:
Allergen, Food, Oyster
OYSTER
CPT Code(s):
86003
0055250
Methodology:
Allergen, Food, Papaya
PAPAYA
CPT Code(s):
86003
0099492
Methodology:
Allergen, Food, Parsley
PARSLEY
CPT Code(s):
86003
0099895
Methodology:
Allergen, Food, Pea
PEA
CPT Code(s):
86003
0099582
Methodology:
Allergen, Food, Peach
PEACH
CPT Code(s):
86003
Page | 33
0055024
Methodology:
Allergen, Food, Peanut
PEANUT
CPT Code(s):
86003
2007211
Methodology:
Allergen, Food, Peanut Components (uKnow®) IgE
PEANUT COM
Multiple patient encounters should be avoided
Specimen Required: Collect: Serum separator tube (SST). Multiple specimen tubes should be avoided
Tube. (Min: 0.25 mL)
Unacceptable Conditions: Hemolyzed, icteric, or lipemic specimens
CPT Code(s):
86003 x7
0097648
Allergen, Food, Peanut IgG
PEANUT IGG
Methodology:
CPT Code(s):
86001
0055207
Methodology:
Allergen, Food, Pear
PEAR
CPT Code(s):
86003
0099572
Methodology:
Allergen, Food, Pecan
PECAN
CPT Code(s):
86003
0055002
Methodology:
Allergen, Food, Pepper C. annuum IgE
BELL
CPT Code(s):
86003
0055428
Methodology:
Allergen, Food, Pepper C. frutescens IgE
CHILI PEP
CPT Code(s):
86003
Page | 34
0099687
Allergen, Food, Perch IgE
Methodology:
CPT Code(s):
86003
PERCH
0055445
Methodology:
Allergen, Food, Pine (Pinon) Nut
PINON NUT
CPT Code(s):
86003
0099477
Methodology:
Allergen, Food, Pineapple
PINEAPPLE
CPT Code(s):
86003
0055447
Methodology:
Allergen, Food, Pistachio
PISTACHIO
CPT Code(s):
86003
0055448
Methodology:
Allergen, Food, Plum
PLUM
CPT Code(s):
86003
0098858
Methodology:
Allergen, Food, Poppy Seed IgE
POPPY
CPT Code(s):
86003
0099780
Methodology:
Allergen, Food, Pork
PORK
CPT Code(s):
86003
0097649
Methodology:
Page | 35
Allergen, Food, Pork IgG
PORK IGG
CPT Code(s):
86001
0055051
Methodology:
Allergen, Food, Potato
POTATO
CPT Code(s):
86003
0097641
Allergen, Food, Potato (White) IgG
Methodology:
CPT Code(s):
86001
POTATO IGG
2001921
Allergen, Food, Pumpkin Seed IgE
Methodology:
CPT Code(s):
86003
PUMPKIN
0099493
Methodology:
Allergen, Food, Raspberry IgE
RASPBERRY
CPT Code(s):
86003
2001923
Allergen, Food, Red Dye/Carmine (Red 4) IgE
Methodology:
CPT Code(s):
86003
RED DYE
0097628
Allergen, Food, Red Snapper IgE
Methodology:
CPT Code(s):
86003
RED SNAP
0055054
Methodology:
Allergen, Food, Rice
RICE
CPT Code(s):
86003
Page | 36
0097323
Allergen, Food, Rice IgG
RICE IGG
Methodology:
CPT Code(s):
86001
2001925
Allergen, Food, Rosemary IgE
Methodology:
CPT Code(s):
86003
ROSEMARY
0055026
Methodology:
Allergen, Food, Rye
RYE
CPT Code(s):
86003
0097642
Allergen, Food, Rye IgG
Methodology:
CPT Code(s):
86001
RYE IGG
0093514
Allergen, Food, Sage IgE
Methodology:
CPT Code(s):
86003
SAGE IGE
0099680
Methodology:
Allergen, Food, Salmon
SALMON
CPT Code(s):
86003
0097638
Methodology:
Allergen, Food, Sardine IgE
SARDIN IGE
CPT Code(s):
86003
0099495
Methodology:
Allergen, Food, Scallop
SCALLOP
Page | 37
CPT Code(s):
86003
0099698
Methodology:
Allergen, Food, Sesame Seed
SESAME
CPT Code(s):
86003
0055030
Methodology:
Allergen, Food, Shrimp
SHRIMP
CPT Code(s):
86003
0093512
Allergen, Food, Sole IgE
Methodology:
CPT Code(s):
86003
SOLE
0055031
Methodology:
Allergen, Food, Soybean
SOY
CPT Code(s):
86003
0097643
Allergen, Food, Soybean IgG
SOY IGG
Methodology:
Specimen Preparation: Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum at to an ARUP Standard Transport
CPT Code(s):
86001
0055208
Methodology:
Allergen, Food, Spinach
SPINACH
CPT Code(s):
86003
0097632
Methodology:
Allergen, Food, Squid IgE
SQUID IGE
CPT Code(s):
86003
Page | 38
0099639
Methodology:
Allergen, Food, Strawberry
STRAWBERRY
CPT Code(s):
86003
0098645
Allergen, Food, Sugar Beet IgE
Methodology:
CPT Code(s):
86003
SUGARBEET
0099736
Allergen, Food, Sugar Cane IgE
Methodology:
CPT Code(s):
86003
SUGARCANE
0097911
Allergen, Food, Sugar Cane IgG4
Methodology:
Quantitative Enzyme Immunoassay
Specimen Preparation: Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL/allergen)
Stability: Ambient: 1 month; Refrigerated: 1 month; Frozen: 2 months
CPT Code(s):
86001
SUGAR IGG4
0099122
Allergen, Food, Summer Squash IgE
Methodology:
CPT Code(s):
86003
SQUASH SUM
0099496
Methodology:
Allergen, Food, Sunflower Seed IgE
SUNFL SEED
CPT Code(s):
86003
0097326
Methodology:
Allergen, Food, Sweet Potato IgE
SWTPOTATO
CPT Code(s):
86003
0097633
Allergen, Food, Swordfish IgE
Methodology:
CPT Code(s):
86003
Page | 39
SWORD IGE
0055451
Methodology:
Allergen, Food, Tea
TEA
CPT Code(s):
86003
0093510
Allergen, Food, Thyme IgE
Methodology:
CPT Code(s):
86003
THYME
2003296
Allergen, Food, Tilapia IgE
Methodology:
CPT Code(s):
86003
TILAPIA
0055033
Methodology:
Allergen, Food, Tomato
TOMATO
CPT Code(s):
86003
0099727
Methodology:
Allergen, Food, Trout
TROUT
CPT Code(s):
86003
0055062
Methodology:
Allergen, Food, Tuna
TUNA
CPT Code(s):
86003
0099627
Methodology:
Allergen, Food, Turkey
TURKEY
CPT Code(s):
86003
0055452
Methodology:
Allergen, Food, Vanilla
Page | 40
VANILLA
CPT Code(s):
86003
0055209
Methodology:
Allergen, Food, Walnut (Juglans spp.) IgE
WALNUT ENG
CPT Code(s):
86003
0055157
Methodology:
Allergen, Food, Watermelon
WATERME
CPT Code(s):
86003
0055034
Methodology:
Allergen, Food, Wheat
WHEAT
CPT Code(s):
86003
0097636
Allergen, Food, Wheat IgG
WHEAT IGG
Methodology:
CPT Code(s):
86001
0055453
Methodology:
Allergen, Food, Whey
WHEY
CPT Code(s):
86003
0090291
Allergen, Food, Whey IgG
WHEY IGG
Methodology:
Specimen Required: Collect: Serum separator tube
Unacceptable Conditions: Hemolyzed, icteric, or lipemic specimens
CPT Code(s):
86001
Page | 41
0097634
Allergen, Food, Whitefish IgE
Methodology:
CPT Code(s):
86003
WFISH
0097325
Allergen, Food, Yam IgE
Methodology:
CPT Code(s):
86003
YAM
0099134
Allergen, Food, Zucchini IgE
Methodology:
CPT Code(s):
86003
ZUCCHINI
0050147
Methodology:
Allergen, Fungi & Molds, Trichophyton mentagrophytes, Interdigitale Variant
TRICOPHYT
CPT Code(s):
86003
0055001
Methodology:
Allergen, Fungi & Molds, Alternaria alternata (tenuis)
ALTER
CPT Code(s):
86003
0097773
Allergen, Fungi and Molds, Alternaria tenuis IgG
Methodology:
CPT Code(s):
86001
ALTER IGG
0055061
Methodology:
Allergen, Fungi & Molds, Aspergillus fumigatus
ASP RAST
CPT Code(s):
86003
0092598
Methodology:
Allergen, Fungi and Molds, Aspergillus niger IgE
ASPNIG IGE
Page | 42
CPT Code(s):
86003
0055383
Methodology:
Allergen, Fungi & Molds, Aureobasidium pullulans
AUREOBASID
CPT Code(s):
86003
0097305
Allergen, Fungi and Molds, Aureobasidium pullulans IgG
AUREO IGG
Methodology:
CPT Code(s):
86001
2004670
Allergen, Fungi and Molds, Botrytis cinerea IgE
BOTRYTIS
Methodology:
Specimen Required: Collect: Serum separator tube. Multiple specimen draws should be avoided.
CPT Code(s):
86003
0055004
Methodology:
Allergen, Fungi & Molds, Candida albicans
CAN RAST
CPT Code(s):
86003
0097304
Allergen, Fungi and Molds, Candida albicans IgG
CANDIDAIGG
Methodology:
CPT Code(s):
86001
0098522
Methodology:
Allergen, Fungi & Molds, Cephalosporium
CEPHALOSPO
CPT Code(s):
86003
0097314
Allergen, Fungi and Molds, Cladosporium IgG
CLADO IGG
Methodology:
CPT Code(s):
86001
0055377
Methodology:
Page | 43
Allergen, Fungi & Molds, Curvularia lunata
CURVULARIA
CPT Code(s):
86003
0099599
Methodology:
Allergen, Fungi & Molds, Epicoccum
EPICOCCUM
CPT Code(s):
86003
0055376
Methodology:
Allergen, Fungi & Molds, Fusarium moniliforme
FUSARIUMMO
CPT Code(s):
86003
0093454
Allergen, Fungi and Molds, Fusarium proliferatum/moniliforme IgG
FUS M IGG
Methodology:
CPT Code(s):
86001-90
0099541
Methodology:
Allergen, Fungi & Molds, Helminthosporium
HELMIN
CPT Code(s):
86003
0097313
Allergen, Fungi and Molds, Helminthosporium halodes/Setomelanomma rostrata IgG
HELMINIGG
Methodology:
CPT Code(s):
86001
0055038
Methodology:
Allergen, Fungi & Molds, Hormodendrum (Cladosporium)
HORMO
CPT Code(s):
86003
0055442
Methodology:
Allergen, Fungi & Molds, Mucor racemosus
Page | 44
MUCOR RAC
CPT Code(s):
86003
0097316
Allergen, Fungi and Molds, Mucor racemosus IgG
MUCOR IGG
Methodology:
CPT Code(s):
86001
0097310
Allergen, Fungi and Molds, Penicillium chrysogenum/notatum IgG
PENI N IGG
Methodology:
CPT Code(s):
86001
0055080
Methodology:
Allergen, Fungi & Molds, Penicillium notatum
PENICIL
CPT Code(s):
86003
0055390
Methodology:
Allergen, Fungi & Molds, Phoma betae
PHOMA
CPT Code(s):
86003
0097309
Allergen, Fungi and Molds, Phoma betae IgG
PHOMAB IGG
Methodology:
CPT Code(s):
86001
2006438
Methodology:
Allergen, Fungi and Molds, Pityrosporum orbiculare/Malassezia IgE
MALASSEZIA
CPT Code(s):
86003
0099555
Methodology:
Allergen, Fungi & Molds, Rhizopus nigricans
RHIZOPUS
Page | 45
CPT Code(s):
86003
0097307
Allergen, Fungi and Molds, Rhizopus nigricans IgG
RHIZO IGG
Methodology:
CPT Code(s):
86001
0092590
Methodology:
Allergen, Fungi and Molds, Staphylococcal Enterotoxin A IgE
STAPHA IGE
CPT Code(s):
86003
0092588
Methodology:
Allergen, Fungi and Molds, Staphylococcal Enterotoxin B IgE
STAPHB IGE
CPT Code(s):
86003
0050357
Methodology:
Allergen, Fungi & Molds, Stemphylium botryosum
STEMPHYLIU
CPT Code(s):
86003 per allergen tested
0099551
Allergen, Fungi and Molds, Stemphylium solani IgE
Methodology:
CPT Code(s):
86003
STEMPH
0090393
Allergen, Fungi and Molds, Trichophyton rubrum IgG
Methodology:
CPT Code(s):
86671
TRICHO IGG
0099901
Methodology:
Allergen, Grass, Alfalfa IgE
ALFALFA
CPT Code(s):
86003
0055151
Methodology:
Page | 46
Allergen, Grass, Bahia
BAHIA
CPT Code(s):
86003
0098644
Allergen, Grass, Barley Pollen, Cultivated IgE
Methodology:
CPT Code(s):
86003
BARLEY POL
0055057
Methodology:
Allergen, Grass, Bent Grass/Redtop Grass
BENT GRASS
CPT Code(s):
86003
0055070
Methodology:
Allergen, Grass, Bermuda
BERMUDA
CPT Code(s):
86003
0099774
Methodology:
Allergen, Grass, Brome Grass
BROMEGRASS
CPT Code(s):
86003
0050536
Methodology:
Allergen, Grass, Canary Grass
CANARY
CPT Code(s):
86003
0098641
Methodology:
Allergen, Grass, Cultivated Corn Pollen
CORN POL
CPT Code(s):
86003
0050533
Methodology:
Allergen, Grass, Cultivated Oat Pollen
CUL OAT
Page | 47
CPT Code(s):
86003
0098642
Methodology:
Allergen, Grass, Cultivated Wheat Pollen
WHEAT POL
CPT Code(s):
86003
0055047
Methodology:
Allergen, Grass, Johnson Grass
JOHN
CPT Code(s):
86003
0055017
Methodology:
Allergen, Grass, June Grass/Kentucky Bluegrass
JUNE
CPT Code(s):
86003
0055053
Methodology:
Allergen, Grass, Meadow Fescue
MEADOW
CPT Code(s):
86003
0055052
Methodology:
Allergen, Grass, Orchard Grass/Cocksfoot
ORCHARD
CPT Code(s):
86003
0055028
Methodology:
Allergen, Grass, Perennial Rye Grass
RYEGRASS
CPT Code(s):
86003
Page | 48
0055184
Allergen, Grass, Reed Pollen, Common IgE
Methodology:
CPT Code(s):
86003
REED POL
0098470
Methodology:
Allergen, Grass, Salt Grass IgE
SALT GRASS
CPT Code(s):
86003
0099667
Methodology:
Allergen, Grass, Sweet Vernal Grass
VERNAL
CPT Code(s):
86003
0055032
Methodology:
Allergen, Grass, Timothy Grass
TIM
CPT Code(s):
86003
0055091
Methodology:
Allergen, House Dust Greer
HOUSEGREER
CPT Code(s):
86003
0055092
Methodology:
Allergen, House Dust Stier
HOUSESTIER
CPT Code(s):
86003
0055210
Methodology:
Allergen, Insect, Mosquito, IgE
MOSQUITO
CPT Code(s):
86003
0050151
Methodology:
Page | 49
Allergen, Insects & Venom, Cockroach, American
COCKROAAM
CPT Code(s):
86003
0055088
Methodology:
Allergen, Insects & Venom, Cockroach, German
COCKROACH
CPT Code(s):
86003
0098272
Methodology:
Allergen, Insects & Venom, Fire Ant, Imported
FIRE ANT
CPT Code(s):
86003
0055039
Methodology:
Allergen, Insects and Venom, Honey Bee IgE
HONEY
CPT Code(s):
86003
0055400
Allergen, Insects and Venom, Honey Bee IgG
HON B IGG
Methodology:
CPT Code(s):
86001
0055048
Methodology:
Allergen, Insects & Venom, Paper Wasp
WASP PAPER
CPT Code(s):
86003
0055415
Allergen, Insects and Venom, Paper Wasp IgG
PAP-W IGG
Methodology:
CPT Code(s):
86001
0055405
Allergen, Insects and Venom, White-Faced Hornet IgG
WH F IGG
Methodology:
Page | 50
CPT Code(s):
86001
0055046
Methodology:
Allergen, Insects & Venom, White-Faced Hornet
HORNET WF
CPT Code(s):
86003
0055420
Allergen, Insects and Venom, Yellow Hornet IgG
YE F IGG
Methodology:
CPT Code(s):
86001
0055410
Allergen, Insects and Venom, Yellow Jacket IgG
YEL J IGG
Methodology:
CPT Code(s):
86001
0055139
Methodology:
Allergen, Insects & Venom, Yellow Jacket Venom
YELLOW J
CPT Code(s):
86003
0055065
Methodology:
Allergen, Insects & Venom, Yellow-Faced Hornet
HORNET YF
CPT Code(s):
86003
0092580
Allergen, Latex Specific IgE Panel by RIA
Methodology:
Specimen Preparation: Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min 1 mL)
Stability: After separation from cells: Ambient: 1 month; Refrigerated: 1 month; Frozen: 1 year
CPT Code(s):
86003 x3
0055009
Methodology:
LATEX RIA
Allergen, Mites, Acarus siro IgE
A SIRO
CPT Code(s):
86003
Page | 51
2006019
Methodology:
Allergen, Mites, B. tropicalis
BTROPIC
Specimen Preparation: Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.25 mL serum plus 0.1 mL for each
additional allergen ordered to an ARUP Standard Transport Tube. (Min: 0.25 mL plus 0.04 mL/additional allergen)
Stability: After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; frozen: 1 year
CPT Code(s):
86003
0055064
Methodology:
Allergen, Mites, D. farinae
DFARI
CPT Code(s):
86003
0055060
Methodology:
Allergen, Mites, D. microceras IgE
D MICROCER
CPT Code(s):
86003
0055063
Methodology:
Allergen, Mites, D. pteronyssinus
DPTER
CPT Code(s):
86003
0055087
Allergen, Mites, Euroglyphus maynei IgE
Methodology:
CPT Code(s):
86003
E MAYNEI
0055095
Methodology:
Allergen, Mites, Glycyphagus domesticus IgE
G DOMESTIC
CPT Code(s):
86003
0050143
Methodology:
Allergen, Mites, Lepidoglyphus destructor
LEPIDOGLY
CPT Code(s):
86003
0055183
Methodology:
Page | 52
Allergen, Mites, Tyrophagus putrescentiae IgE
T PUTRE
CPT Code(s):
86003
2006687
Methodology:
Allergen, Occupational, Cotton Seed IgE
COTTONSEED
CPT Code(s):
86003
0098421
Allergen, Occupational, Ethylene Oxide IgE
Methodology:
CPT Code(s):
86003
ETHYLENE
0098423
Allergen, Occupational, Formaldehyde IgE
Methodology:
CPT Code(s):
86003
FORMALD
2001915
Allergen, Occupational, Gum Carageenan IgE
Methodology:
CPT Code(s):
86003
GUM CARAGE
0098418
Methodology:
Allergen, Occupational, Isocyanate HDI
ISO HDI
CPT Code(s):
86003
0098419
Methodology:
Allergen, Occupational, Isocyanate MDI
ISO MDI
CPT Code(s):
86003
0098420
Methodology:
Allergen, Occupational, Isocyanate TDI
ISO TDI
CPT Code(s):
86003
Page | 53
0099614
Methodology:
Allergen, Occupational, Latex
LATEX
CPT Code(s):
86003
0098422
Allergen, Occupational, Phthalic Anhydride IgE
Methodology:
CPT Code(s):
86003
ANHYD
0099548
Methodology:
Allergen, Occupational, Tobacco
TOB
CPT Code(s):
86003
2005894
Allergen Panel, IgE by ImmunoCap ISAC
Methodology:
Semi-Quantitative ImmunoCAP® Solid-phase Allergen Chip
Specimen Required: Collect: Serum separator tube. Also acceptable: Lavender (EDTA) or green (sodium or lithium) heparin.
Unacceptable Conditions: Ambient specimens.
Stability: Ambient: Unacceptable; Refrigerated: 1 week; Frozen at -20 °C: 1 month;
Frozen at -70 °C: Indefinite
CPT Code(s):
86003 x112
ISAC MICRO
0055213
Methodology:
Allergen, Parasite, Ascaris
ASCARIS
CPT Code(s):
86003
0055141
Methodology:
Allergen, Tree, Acacia Tree
ACACIA
CPT Code(s):
86003
0099486
Methodology:
Allergen, Tree, Alder Tree
ALDER
CPT Code(s):
86003
0055153
Methodology:
Allergen, Tree, American Beech Tree
Fasting specimen preferred. Multiple patient encounters should be avoided.
Page | 54
AMBEE
CPT Code(s):
86003
0055150
Allergen, Tree, Arizona Cypress IgE
Methodology:
CPT Code(s):
86003
ARIZ CYP
0098870
Methodology:
Allergen, Tree, Bayberry IgE
BAYBERRY
allergen ordered to an ARUP Standard Transport Tube. (Min: 0.25 mL plus 0.04 mL/additional allergen)
CPT Code(s):
86003
0055058
Methodology:
Allergen, Tree, Birch Tree
BIRCH
CPT Code(s):
86003
0092053
Allergen, Tree, Black Locust IgE
Methodology:
CPT Code(s):
86003
BLK LOCUST
0055003
Methodology:
Allergen, Tree, Box Elder/Maple Tree
BOX
CPT Code(s):
86003
0097794
Allergen, Tree, California Pepper IgE
Methodology:
CPT Code(s):
86003
0055156
Methodology:
PEPPERTREE
Allergen, Tree, Cedar/Red Tree
CEDARRED
CPT Code(s):
86003
Page | 55
0055010
Methodology:
Allergen, Tree, Cottonwood Tree
COTTON
CPT Code(s):
86003
2003216
Allergen, Tree, Douglas Fir IgE
Methodology:
CPT Code(s):
86003
DOUGLAS
0055042
Methodology:
Allergen, Tree, Elm Tree
ELM
CPT Code(s):
86003
0055098
Methodology:
Allergen, Tree, Eucalyptus Tree
EUCAL
CPT Code(s):
86003
0098871
Allergen, Tree, Groundsel IgE
Methodology:
CPT Code(s):
86003
BUCCHARIS
0093506
Methodology:
Allergen, Tree, Hazelnut IgE
HAZEL NUT
CPT Code(s):
86003
0097934
Allergen, Tree, Hickory Shagbark IgE
Methodology:
CPT Code(s):
86003
0098867
Methodology:
SHAGBARK
Allergen, Tree, Italian Cypress IgE
CYPRESS IT
Page | 56
CPT Code(s):
86003
0055187
Methodology:
Allergen, Tree, Japanese Cedar Tree
J CEDAR
CPT Code(s):
86003
0098863
Methodology:
Allergen, Tree, Melaleuca Tree IgE
MELALEUCA
CPT Code(s):
86003
0055140
Methodology:
Allergen, Tree, Mesquite Tree
MESQUITE
CPT Code(s):
86003
0055007
Methodology:
Allergen, Tree, Mountain Cedar (Juniper) Tree
CEDAR
CPT Code(s):
86003
0093504
Methodology:
Allergen, Tree, Mulberry Red IgE
MULBERRY
CPT Code(s):
86003
0097933
Allergen, Tree, Oak Red IgE
Methodology:
CPT Code(s):
86003
0055045
Methodology:
OAK RED
Allergen, Tree, Oak Tree
OAK
CPT Code(s):
86003
Page | 57
0055155
Methodology:
Allergen, Tree, Olive Tree
OLIVE TREE
CPT Code(s):
86003
0098861
Methodology:
Allergen, Tree, Palm/Queen Tree IgE
PALM Q
CPT Code(s):
86003
0055145
Methodology:
Allergen, Tree, Pecan (White Hickory) Tree
PECAN TREE
CPT Code(s):
86003
0055089
Methodology:
Allergen, Tree, Pine/Australian Tree
PINEAUS
CPT Code(s):
86003
0098859
Allergen, Tree, Poplar White IgE
Methodology:
CPT Code(s):
86003
POPLAR W
0055152
Methodology:
Allergen, Tree, Privet Tree
PRIVET
CPT Code(s):
86003
0055380
Methodology:
Allergen, Tree, Sweet Gum Tree
SWEETGUMTR
CPT Code(s):
86003
0055090
Methodology:
Page | 58
Allergen, Tree, Sycamore Tree
SYCAMORE
CPT Code(s):
86003
0055449
Methodology:
Allergen, Tree, Virginia Live Oak Tree
VOAK
CPT Code(s):
86003
0055093
Methodology:
Allergen, Tree, Walnut Tree
WALNUT TR
CPT Code(s):
86003
0055073
Methodology:
Allergen, Tree, White Ash Tree
ASH
CPT Code(s):
86003
0099554
Methodology:
Allergen, Tree, White Mulberry Tree
MULB
CPT Code(s):
86003
0055082
Methodology:
Allergen, Tree, White Pine Tree
PINE
CPT Code(s):
86003
0055083
Methodology:
Allergen, Tree, Willow Tree
WILLOW
CPT Code(s):
86003
0099472
Methodology:
Page | 59
Allergen, Weed, Cocklebur
COCKLEBUR
CPT Code(s):
86003
0055085
Methodology:
Allergen, Weed, Common/Short Ragweed
CRAG
CPT Code(s):
86003
0055086
Methodology:
Allergen, Weed, Dandelion
DANDY
CPT Code(s):
86003
0055049
Methodology:
Allergen, Weed, English Plantain
ENGLISH
CPT Code(s):
86003
0055014
Methodology:
Allergen, Weed, False Ragweed
FRAG
CPT Code(s):
86003
0055084
Methodology:
Allergen, Weed, Giant Ragweed
GRAG
CPT Code(s):
86003
0098471
Methodology:
Allergen, Weed, Goldenrod
GOLDENROD
CPT Code(s):
86003
0055018
Methodology:
Allergen, Weed, Kochia/Firebush
Page | 60
KOCHIA
CPT Code(s):
86003
0055160
Methodology:
Allergen, Weed, Lamb's Quarters
LAMBS QTR
CPT Code(s):
86003
0050910
Methodology:
Allergen, Weed, Marsh Elder
MARSHELDER
CPT Code(s):
86003
0055021
Methodology:
Allergen, Weed, Mugwort
MUGWORT
CPT Code(s):
86003
0099775
Methodology:
Allergen, Weed, Nettle
NETTLE
CPT Code(s):
86003
0055025
Methodology:
Allergen, Weed, Pigweed
PIG
CPT Code(s):
86003
0055027
Methodology:
Allergen, Weed, Russian Thistle
RUSSIAN
CPT Code(s):
86003
0055029
Methodology:
Allergen, Weed, Sagebrush/Wormwood
Page | 61
SAGE
CPT Code(s):
86003
0099553
Methodology:
Allergen, Weed, Scale
SCALE
CPT Code(s):
86003
0099785
Methodology:
Allergen, Weed, Sheep Sorrel
SHEEP SORR
CPT Code(s):
86003
0055185
Allergen, Weed, Sunflower Pollen IgE
Methodology:
CPT Code(s):
86003
SUNFL POL
2006021
Methodology:
Allergen, Weed, Wall pellitory (P. officinalis)
WALL PELL
allergen ordered to an ARUP Standard Transport Tube. (Min: 0.25 mL plus 0.04 mL/additional allergen)
CPT Code(s):
86003
0055035
Methodology:
Allergen, Weed, Western Ragweed
WRAG
CPT Code(s):
86003
0098433
Methodology:
Allergen, Weed, Yellow Dock (Rumex crispus)
DOCK YEL
CPT Code(s):
86003
0051833
Methodology:
Allergens, Additional Molds Profile IgE
MOLD PRO
ImmunoCAP® Fluorescent Enzyme Immunoassay
Specimen Preparation: Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.65 mL to an ARUP Standard Transport Tube.
(Min: 0.45 mL)
Page | 62
CPT Code(s):
86003 x5 IgE specific allergens
0055122
Methodology:
Allergens, Animal, Dog/Cat Epithelium Profile
EPI PAN 2
CPT Code(s):
86003 per allergen
0055120
Methodology:
Allergens, Animal Epithelium/Dander/Feather Mix Profile
EPI PAN
Tube. (Min: 0.4 mL)
CPT Code(s):
86003 per allergen
0055170
Methodology:
Allergens, Dust/Mite Profile
DUSTPRO 4
CPT Code(s):
86003 per allergen
0055350
Methodology:
Allergens, Food, Cereal Profile
CEREAL
Tube. (Min: 0.4 mL)
CPT Code(s):
86003 per allergen
0050486
Methodology:
Allergens, Food, Common Adult Food
FOOD ADULT
CPT Code(s):
86003 per allergen; 82785 IgE
2007215
Allergens, Food, Common Panel IgG
G FOOD COM
Methodology:
CPT Code(s):
86001 x18
Page | 63
0055100
Methodology:
Allergens, Food, Comprehensive Profile 1
FOOD PAN
CPT Code(s):
86003 per allergen
2007213
Allergens, Food, Extended Panel IgG
G FOOD PAN
Methodology:
CPT Code(s):
86001 x19
2007036
Methodology:
Allergens, Food, Fish Profile IgE
FISH GROUP
Specimen Required: Collect: Serum separator tube (SST). Multiple specimen tubes should be avoided.
Specimen Preparation: Separate serum from cells ASAP or within 2 hours of collection. Transport 0.8 mL serum to an ARUP Standard Transport
Tube. (Min: 0.5 mL)
Stability: After separation from cells: Ambient 2 days; Refrigerated: 2 weeks; Frozen: 1 year
CPT Code(s):
86003 x6 IgE-specific allergens
2007216
Allergens, Food, IgG Panel
IGG FOOD
Methodology:
CPT Code(s):
86001 x11
2007214
Allergens, Food, Meat Panel IgG
IGG MEATS
Methodology:
CPT Code(s):
86001 x3
0055345
Methodology:
Allergens, Food, Nut Mix Profile
NUT MIX
Tube. (Min: 0.4 mL)
CPT Code(s):
86003 per allergen
0051831
Methodology:
Allergens, Food, Nuts
MIXEDNUTS
CPT Code(s):
86003 per allergen
0055142
Methodology:
Page | 64
Allergens, Food, Profile 4
ALL PRO B
CPT Code(s):
86003 per allergen
0055133
Methodology:
FOOD 8
CPT Code(s):
86003 per allergen
0055104
Methodology:
FOOD PAN 9
CPT Code(s):
86003 per allergen
0055174
Methodology:
FOODPRO 10
Tube. (Min: 0.6 mL)
CPT Code(s):
86003 per allergen
0055301
Methodology:
FOOD 13
CPT Code(s):
86003 per allergen
0055172
Methodology:
FOODPRO 19
CPT Code(s):
86003 per allergen
0055340
Methodology:
Allergens, Food, Salad Profile
SALAD
Tube. (Min: 0.4 mL)
CPT Code(s):
86003 per allergen
0055335
Methodology:
Allergens, Food, Seafood Profile
Page | 65
SEAFOOD
CPT Code(s):
Tube. (Min: 0.4 mL)
86003 per allergen
0051835
Methodology:
Allergens, Food, Shell Fish Profile
SHELLFISH
CPT Code(s):
86003 per allergen
0055384
Methodology:
Allergens, Food, Southeast Profile
GAFOODPROF
CPT Code(s):
86003 per allergen
0055370
Methodology:
Allergens, Food, Southwest Basic Profile
SWFOOD
CPT Code(s):
86003 per allergen
0055330
Methodology:
Allergens, Food, Vegetable Profile
VEG PRO
Tube. (Min: 0.4 mL)
CPT Code(s):
86003 per allergen
0055218
Methodology:
Allergens, Food, West Kentucky Group
WKTFOOD
Tube. (Min: 1 mL)
CPT Code(s):
86003 x10 IgE-specific allergens; 82785 IgE, Total Quantitative
2002124
Methodology:
Allergens, Foods, Common 10
COMMONFOOD
(Min: 0.8 mL)
CPT Code(s):
86003 x10
0055130
Methodology:
Allergens, Grass Profile
Page | 66
GRASS PAN
CPT Code(s):
86003 per allergen
0055105
Methodology:
Allergens, Hymenoptera, Bee Venom Profile
BEE PAN
Tube. (Min: 0.4 mL)
CPT Code(s):
86003 per allergen
0055368
Allergens, Inhalant Multiallergen IgE, Qualitative
Methodology:
Qualitative ImmunoCAP® Fluorescent Enzyme Immunoassay
Unacceptable Conditions: Contaminated, heat-inactivated, or hemolyzed specimens.
Stability: After separation from cells: Ambient: 8 hours; Refrigerated: 48 hours; Frozen: 6 months
CPT Code(s):
83516
INHALALL
0055309
Methodology:
Allergens, Inhalants, California Environmental
CA ENV PAN
Tube. (Min: 0.4 mL)
CPT Code(s):
86003 per allergen
0055306
Methodology:
Allergens, Inhalants, California Pollen
CA POL PAN
Tube. (Min: 0.6 mL)
CPT Code(s):
86003 per allergen
0055312
Methodology:
Allergens, Inhalants, Comprehensive Profile
AZ TOT PAN
CPT Code(s):
86003 per allergen; 82785 IgE, Total Quantitative
0055231
Methodology:
Allergens, Inhalants, Comprehensive Profile 2
REGRAST
CPT Code(s):
86003 per allergen
0055305
Methodology:
Allergens, Inhalants, Environmental Profile 10
ENVIRO 10
Tube. (Min: 0.6 mL)
Page | 67
CPT Code(s):
86003 per allergen
0055114
Methodology:
Allergens, Inhalants/Foods, Comprehensive Profile 1
COMP PAN
CPT Code(s):
86003 per allergen
0055099
Methodology:
Allergens, Inhalants/Foods, Comprehensive Profile 2
COMP 29
CPT Code(s):
86003 per allergen
0055307
Methodology:
Allergens, Inhalants/Foods, Environmental Profile
FOOD ENV
CPT Code(s):
86003 per allergen
0055131
Methodology:
Allergens, Inhalants/Foods, Pacific Northwest Profile
PACIFIC NW
CPT Code(s):
86003 per allergen
0055126
Methodology:
Allergens, Inhalants/Foods, Profile A
ALL PRO A
CPT Code(s):
86003 per allergen
0055240
Methodology:
Allergens, Inhalants/Foods, Southeast Profile
SE PRO
CPT Code(s):
86003 per allergen
0055129
Methodology:
Allergens, Inhalants/Foods, Western Allergy Profile
WEST PAN
Page | 68
CPT Code(s):
86003 per allergen
0050493
Methodology:
Allergens, Inhalants, Hawaii Perennial Panel
PER PAN
CPT Code(s):
86003 per allergen tested
0051830
Methodology:
Allergens, Inhalants, Indoor
INDOOR
(Min: 0.48 mL)
Stability: After separation from cells: Ambient 48 hours; Refrigerated: 2 weeks; Frozen: 1 year
CPT Code(s):
0055138
Methodology:
Allergens, Inhalants, Midwest Comprehensive 1
MIDWEST
CPT Code(s):
86003 per allergen
0055171
Methodology:
Allergens, Inhalants, Midwest Comprehensive 2
MWPRO 19
CPT Code(s):
86003 per allergen
0055116
Methodology:
Allergens, Inhalants, Northeast Comprehensive
NORTHEAST
Tube. (Min: 0.8 mL)
CPT Code(s):
86003 per allergen
0055113
Methodology:
Allergens, Inhalants Panel 11 IgE
INHALE 11
(Min: 1.00 mL)
Unacceptable Conditions: Hemolyzed, icteric or lipemic samples.
CPT Code(s):
86003 x10 IgE specific allergens; 82785 Total IgE
Page | 69
0055175
Methodology:
Allergens, Inhalants, Profile 13 IgE
COMPPRO 13
CPT Code(s):
86003 x12
0055178
Methodology:
COMPPRO 18
CPT Code(s):
86003 x17
2002123
Methodology:
INHALE 28
(Min: 1.6 mL)
CPT Code(s):
86003 x28
0055149
Methodology:
Allergens, Inhalants, Southeast Coastal Comprehensive
SECOASTPAN
CPT Code(s):
86003 per allergen
0055111
Methodology:
Allergens, Inhalants, Southern California Profile
SO CAL PAN
Tube. (Min: 0.6 mL)
CPT Code(s):
86003 per allergen
0055043
Methodology:
Allergens, Inhalants, Southwest Basic
SW PRO
CPT Code(s):
86003 per allergen
0055360
Methodology:
Allergens, Inhalants, Southwest Comprehensive 1
SWADULT
Tube. (Min: 1 mL)
CPT Code(s):
86003 per allergen
Page | 70
0055367
Methodology:
Allergens, Inhalants, Southwest Comprehensive 2
SWINHALE
CPT Code(s):
86003 per allergen
0055375
Methodology:
Allergens, Inhalants, Southwest Extended Profile
SWEXT
CPT Code(s):
86003 per allergen
0055230
Methodology:
Allergens, Inhalants, Southwest Valley Profile
SW VALLEY
Tube. (Min: 0.6 mL)
CPT Code(s):
86003 per allergen
0055395
Methodology:
Allergens, Isocyanate Panel
ISOCYANPAN
CPT Code(s):
86003 per allergen
0055245
Methodology:
Allergens, Latex/Cross-Reactive Food Panel
LATEX FOOD
Tube. (Min: 1 mL)
CPT Code(s):
86003 per allergen tested; 82785 IgE
0055125
Methodology:
Allergens, Mold Profile
MOLD PAN
Tube. (Min: 0.4 mL)
CPT Code(s):
86003 per allergen
0055387
Methodology:
Allergens, Mold Profile, Southeast Comprehensive
SEMOLDPRO
Tube. (Min: 0.6 mL)
CPT Code(s):
86003 per allergen
Page | 71
0050529
Methodology:
Allergens, Pediatric Allergy, March (Progression) Profile
PED MARCH
CPT Code(s):
86003 per allergen; 82785 IgE
0055300
Methodology:
Allergens, Pediatric Foods/Inhalants Profile
PED PAN 2
CPT Code(s):
86003 per allergen
0055121
Methodology:
Allergens, Pediatric Foods Profile 1
PED PAN
Tube. (Min: 0.4 mL)
CPT Code(s):
86003 per allergen
0055365
Methodology:
Allergens, Pediatric Inhalants, Southwest
SWPED
CPT Code(s):
86003 per allergen
0050152
Methodology:
Allergens, Pediatric Profile IgE
M PED PRO
(Min: 0.80 mL)
Unacceptable Conditions: Hemolyzed, icteric or lipemic samples.
CPT Code(s):
2005717
Methodology:
Allergens, Respiratory Panel, Region 1, North Atlantic (CT, MA, NJ, PA, VT, ME, NH, NY, RI)
REG1 PAN
Tube. (Min: 1.4 mL)
CPT Code(s):
2006038
Methodology:
Allergens, Respiratory Panel, Region 10, Southwestern Grasslands (OK, TX)
REG10 PAN
Tube. (Min: 1.5 mL)
CPT Code(s):
86003 x 29 IgE specific allergens; 82785 Total IgE
Page | 72
2006039
Methodology:
Allergens, Respiratory Panel, Region 11, Rocky Mountain (AZ, ID, NM, WY CO, MT, UT)
REG11 PAN
Tube. (Min: 1.4 mL)
Remarks: Refrigerated.
CPT Code(s):
2006040
Methodology:
Allergens, Respiratory Panel, Region 12, Arid Southwest (S. AZ, S.E. CA)
REG12 PAN
Tube. (Min: 1.4 mL)
CPT Code(s):
2006041
Methodology:
Allergens, Respiratory Panel, Region 13, Southern Coastal (CA)
REG13 PAN
Tube. (Min: 1.4 mL)
CPT Code(s):
2006042
Methodology:
Allergens, Respiratory Panel, Region 14, Central California (CA)
REG14 PAN
Tube. (Min: 1.4 mL)
CPT Code(s):
2006043
Methodology:
Allergens, Respiratory Panel, Region 15, Intermountain West (NV, S. ID)
REG15 PAN
Tube. (Min: 1.4 mL)
CPT Code(s):
2006044
Methodology:
Allergens, Respiratory Panel, Region 16, Inland Northwest (OR, Central and East WA)
REG16 PAN
Tube. (Min: 1.3 mL)
CPT Code(s):
2006045
Methodology:
Allergens, Respiratory Panel, Region 17, Pacific Northwest (NW CA, W. OR, WA)
REG17 PAN
Tube. (Min: 1.4 mL)
CPT Code(s):
86003 x 27 IgE specific allergens; 82785 Total IgE
Page | 73
2006046
Methodology:
Allergens, Respiratory Panel, Region 18, Alaska
REG18 PAN
Tube. (Min: 1.1 mL)
CPT Code(s):
2006047
Methodology:
Allergens, Respiratory Panel, Region 19, Puerto Rico
REG19 PAN
Tube. (Min: 1.5 mL)
CPT Code(s):
2005718
Methodology:
Allergens, Respiratory Panel, Region 2, Mid-Atlantic (DE, MD, VA, DC, NC)
REG2 PAN
Tube. (Min: 1.4 mL)
CPT Code(s):
2006048
Methodology:
Allergens, Respiratory Panel, Region 20, Hawaii
REG20 PAN
Tube. (Min: 1.4 mL)
CPT Code(s):
2006025
Methodology:
Allergens, Respiratory Panel, Region 3, South Atlantic (GA, SC, N. FL)
REG3 PAN
Tube. (Min: 1.4 mL)
CPT Code(s):
2006026
Methodology:
Allergens, Respiratory Panel, Region 4, Subtropic Florida (S. of Orlando)
REG4 PAN
Tube. (Min: 1.4 mL)
CPT Code(s):
2006031
Methodology:
Allergens, Respiratory Panel, Region 5, Ohio Valley (IN, OH, TN, WV, KY)
REG5 PAN
Tube. (Min: 1.5 mL)
Page | 74
CPT Code(s):
2006032
Methodology:
Allergens, Respiratory Panel, Region 6, South Central (AL, AR, LA, MS)
REG6 PAN
Tube. (Min: 1.4 mL)
CPT Code(s):
2006033
Methodology:
Allergens, Respiratory Panel, Region 7, Northern Midwest (MI, WI, MN)
REG7 PAN
Tube. (Min: 1.4 mL)
CPT Code(s):
2006034
Methodology:
Allergens, Respiratory Panel, Region 8, Central Midwest (IL, MO, IA)
REG8 PAN
Multiple patient encounters should be avoided
Specimen Required: Collect: Serum separator tube (SST). Multiple specimen tubes should be avoided.
Tube. (Min: 1.4 mL)
CPT Code(s):
2006037
Methodology:
Allergens, Respiratory Panel, Region 9, Great Plains (KS, NE, ND, SD)
REG9 PAN
Tube. (Min: 1.4 mL)
CPT Code(s):
0092584
Methodology:
Allergens, Staphylococcal aureus Panel
STAPHPANII
Specimen Preparation: Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum in an ARUP Standard Transport
Tube. (Min: 0.3 mL)
CPT Code(s):
86003 x2 Staph A, B; 82785 IgE
0055115
Methodology:
Allergens, Tree Profile
TREE PAN
CPT Code(s):
86003 per allergen
Page | 75
0055148
Methodology:
Allergens, Tree Profile 4
TREE PRO 4
Tube. (Min: 0.4 mL)
CPT Code(s):
86003 per allergen
0055385
Methodology:
Allergens, Tree, Southeast Profile
GATREEPRO
CPT Code(s):
86003 per allergen
0051355
Methodology:
Allergens, Upper Respiratory Disease Profile, Region 9A
R9A URD
Unacceptable Conditions: Hemolyzed, icteric or lipemic specimens
CPT Code(s):
86003 x15 IgE-specific allergens
0055110
Methodology:
Allergens, Weed Profile
WEED PAN
CPT Code(s):
86003 per allergen
0055112
Methodology:
Allergens, Weed Profile 5
WEED PAN 5
Tube. (Min: 0.4 mL)
CPT Code(s):
86003 per allergen
0055379
Methodology:
Allergens, Weeds, Southeast Basic Profile
GAWEEDPRO
Tube. (Min: 0.4 mL)
CPT Code(s):
86003 per allergen
2004243
Allergic Bronchopulmonary Aspergillosis (ABPA) Panel
ABPA
Methodology:
Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay/Qualitative Immunodiffusion
Specimen Preparation: Separate serum from cells within 2 hours of collection. Transfer 2.3 mL serum to an ARUP Standard Transport Tube.
(Min: 0.5 mL)
Remarks: Multiple specimen tubes and multiple patient encounters should be avoided.
Unacceptable Conditions: Plasma. Hemolyzed, icteric or lipemic specimens.
Stability: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year
CPT Code(s):
82785 Immunoglobulin E; 86003 Allergen specific IgE; 86606 x2 Aspergillus
Page | 76
0091204
Allopurinol, Serum or Plasma
Methodology:
CPT Code(s):
80299
ALLOPUR SP
2003418
Alpha-1-Antichymotrypsin (A1ACT) by Immunohistochemistry
A1 ACT IHC
Methodology:
CPT Code(s):
88342
0050001
Alpha-1-Antitrypsin
A1A
Methodology:
Quantitative Immunoturbidimetry
Specimen Required: Collect: Plasma separation tube or serum separator tube. Also acceptable: Lavender (EDTA) or pink (K2EDTA).
collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.2 mL)
Stability: After separation from cells: Ambient: 8 hours; Refrigerated: 5 days; Frozen: 3 months (avoid repeated freeze/thaw cycles)
CPT Code(s):
82103
2003424
Alpha-1-Antitrypsin (AAT) by Immunohistochemistry
A1 AT IHC
Methodology:
CPT Code(s):
88342
0099991
Alpha-1-Antitrypsin, Feces
A1A FECES
Methodology:
Quantitative Radial Immunodiffusion
ARUP Connect™ or contact Client Services at (800) 522-2787. (Min: 1 g)
Remarks:
Unacceptable Conditions: Diapers. Specimens in media or preservatives.
Stability: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 1 week
CPT Code(s):
82103
0080500
Alpha-1-Antitrypsin Phenotype (Includes Alpha-1-Antitrypsin)
A1A PHENO
Methodology:
Qualitative Isoelectric Focusing/Immunoturbidimetry
Stability: After separation from cells: Ambient: 8 hours; Refrigerated: 5 days; Frozen: 2 weeks (avoid repeated freeze/thaw cycles)
CPT Code(s):
82104 Alpha-1-antitrypsin, phenotype; 82103 Alpha-1-antitrypsin, total
0051256
Alpha-1-Antitrypsin (SERPINA1) Enzyme Concentration and 2 Mutations with Reflex to Alpha-1-Antitrypsin
A1A GENO
Phenotype
Methodology:
Immunoturbidimetry/Polymerase Chain Reaction/Fluorescence Monitoring/Isoelectric Focusing
Specimen Required: Collect: Serum separator tube AND lavender (EDTA), pink (K2EDTA), or yellow (ACD Solution A or B).
Specimen Preparation: Allow serum to clot completely at room temperature. Separate serum from cells ASAP or within 2 hours of collection.
Transport 0.5 mL serum AND 3 mL whole blood. (Min: 0.5 mL serum AND 0.5 mL whole blood)
Stability: Serum: Ambient: 8 hours; Refrigerated: 5 days; Frozen: 2 weeks
Whole Blood: Ambient: 72 hours; Refrigerated: 1 week; Frozen: Unacceptable
Page | 77
CPT Code(s):
82103 A1A; 83891 Isolation; 83898 x2 Amplification; 83896 x4 Nucleic acid probes; 83912 Interpretation and report. If reflexed, add 82104
Phenotype. Additional CPT code modifiers may be required for procedures performed to test for oncologic or inherited disorders.
2003436
Alpha-1-Fetoprotein (AFP) by Immunohistochemistry
AFP IHC
Methodology:
CPT Code(s):
88342
0050043
Alpha-1-Microglobulin, Urine
A1M
Methodology:
Specimen Required: Collect: 24-hour urine. Specimen must be refrigerated during collection.
Specimen Preparation: Transfer a 4 mL aliquot from a well-mixed 24-hour collection to an ARUP Standard Transport Tube. (Min: 0.4 mL) Do not
add acid or other preservatives. Record total volume and collection time interval on transport tube and test request form.
Unacceptable Conditions: Frozen or preserved specimens.
Stability: Ambient: 8 hours; Refrigerated: 8 days; Frozen: Unacceptable
CPT Code(s):
83883
0098727
Alpha-2-Antiplasmin, Activity
ALPHA 2A
Methodology:
Chromogenic Assay
Specimen Required: Collect: Lt. blue (sodium citrate). Refer to Specimen Handling at aruplab.com for hemostasis/thrombosis specimen handling guidelines
Specimen Preparation: Transfer 1 mL platelet-poor plasma to an ARUP Standard Transport Tube. (Min: 1 mL)
Unacceptable Conditions: Serum. Non-frozen or hemolyzed specimens.
Stability: Ambient: 8 hours; Refrigerated: Unacceptable; Frozen: 1 month
CPT Code(s):
85410
0050005
Alpha-2-Macroglobulin
A2M
Methodology:
Tube. (Min: 0.4 mL) Also acceptable: CSF or pleural fluid (centrifuge and separate to remove cellular material).
Stability: After separation from cells: Ambient: 8 hours; Refrigerated: 8 days; Frozen: 1 year (if frozen within 24 hours). Avoid repeated
freeze/thaw cycles. Ambient: 8 hour sample prep time.
CPT Code(s):
83883
0080427
Methodology:
Alpha Fetoprotein (Amniotic Fluid) with Reflex to Acetylcholinesterase and Fetal Hemoglobin
AFP AF
Chemiluminescent Immunoassay/Electrophoresis
Amniocentesis.
Specimen Required: Collect: Amniotic fluid.
Specimen Preparation: Transport 2.5 mL amniotic fluid. (Min: 1.5mL)
Remarks: Include gestational age at time of collection or estimated due date, physician name and phone number on the test request form.
Unacceptable Conditions: Specimens contaminated with fetal blood.
Stability: Ambient: 2 weeks; Refrigerated: 4 months; Frozen: 3 years
CPT Code(s):
82106 AFP; if reflexed, add 82013 Acetylcholinesterase and 83033 Fetal Hemoglobin
0020729
Alpha Fetoprotein, CSF (Tumor Marker)
Methodology:
Specimen Preparation: Transfer 0.5 mL CSF to an ARUP Standard Transport Tube. (Min: 0.2 mL)
Unacceptable Conditions: Any specimens other than CSF.
Stability: Ambient: 48 hours; Refrigerated: 1 week; Frozen: 1 year
CPT Code(s):
86316
AFP CSF
0080428
Alpha Fetoprotein, Serum (Tumor Marker)
AFP TM
Methodology:
Specimen Preparation: Allow specimen to clot completely at room temperature. Separate serum from cells within 4 hours of collection. Transfer 1
mL serum to an ARUP Standard Transport Tube. (Min: 0.2 mL)
Unacceptable Conditions: CSF (refer to Alpha Fetoprotein, CSF (Tumor Marker), ARUP test code 0020729) or plasma. Grossly hemolyzed
specimens.
Stability: After separation from cells: Ambient: 48 hours; Refrigerated: 1 week; Frozen: 1 year
CPT Code(s):
82105
Page | 78
0081208
Alpha Fetoprotein, Total and L3 Percent
AFP L3
Methodology:
Quantitative Liquid Chromatography/Immunoassay
Specimen Preparation: Allow specimen to clot completely at room temperature. Separate serum from cells ASAP or within 2 hours of collection.
Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Unacceptable Conditions: Plasma.
Stability: After separation from cells: Ambient: 8 hours; Refrigerated: 5 days; Frozen: 3 months (avoid repeated freeze/thaw cycles)
CPT Code(s):
82107
2003204
Alpha Galactosidase, Serum
Methodology:
Fluorometry
Specimen Preparation: Separate from cells. Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.2 mL)
Unacceptable Conditions: Room temperature or refrigerated specimens.
Stability: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 2 weeks
CPT Code(s):
82657
A GALACTO
2001582
Alpha Globin (HBA1 and HBA2) Sequencing
AG FGS
Methodology:
Polymerase Chain Reaction/Sequencing
Specimen Required: Collect: Contact ARUP's genetic counselor at (800) 242-2787 extension 2141 prior to test submission.
CPT Code(s):
83891 Isolation; 83898 x2 Amplification; 83904 x6 Sequencing; 83909 capillary electrophoresis; 83912 Interpretation and report - Additional
CPT code modifiers may be required for procedures performed to test for oncologic or inherited disorders.
2006289
Alpha Subunit of Pituitary Glycoprotein Hormones (Alpha-PGH)
Methodology:
Storage/Transport Temperature: Frozen. Also acceptable: Refrigerated.
Unacceptable Conditions: Grossly hemolyzed specimens.
Stability: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 3 months
CPT Code(s):
83520
A SUBUNIT
2003419
Alpha-Synuclein by Immunohistochemistry
ASYN IHC
Methodology:
CPT Code(s):
88342
0051495
Alpha Thalassemia (HBA1 & HBA2) 7 Deletions
ALPHA THAL
Methodology:
Polymerase Chain Reaction/Gel Electrophoresis
CPT Code(s):
83891 Isolation; 83900 Amplification multiplex; 83901 x8 Additional amplification; 83894 Gel separation; 83912 Interpretation and report Additional CPT code modifiers may be required for procedures performed to test for oncologic or inherited disorders.
0050002
Alpha-1-Acid Glycoprotein
A1A GLYCO
Methodology:
Specimen Preparation: Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP
Standard Transport Tube. (Min: 0.5 mL)
Stability: After separation from cells: Ambient: 8 hours; Refrigerated: 8 days; Frozen: 1 year
CPT Code(s):
82985
Page | 79
0051710
Alport Syndrome, X-Linked (COL4A5) 3 Mutations
ALPORT DNA
Methodology:
CPT Code(s):
83891 Isolation; 83898 Amplification; 83900 Multiplex amplification; 83896 x 6 Nucleic acid probe; 83912 Interpretation and report - Additional
2002394
Alport Syndrome, X-linked (COL4A5) Deletion/Duplication
ALPORT DD
Methodology:
Polymerase Chain Reaction/Multiplex Ligation-dependent Probe Amplification
CPT Code(s):
83891 Isolation; 83896 x2 Nucleic acid probes; 83898 x2 Amplification; 83914 x2 Extension; 83909 x2
Capillary electrophoresis; 83912 Interpretation and report - Additional CPT code modifiers may be required for procedures performed to test for
oncologic or inherited disorders.
0051786
Alport Syndrome, X-linked (COL4A5) Sequencing
ALPORT FGS
Methodology:
Specimen Required: Collect: Lavender (EDTA), pink (K2EDTA) or yellow (ACD Solution A or B).
CPT Code(s):
83891 Isolation; 83898 x46 Amplification; 83904 x46 Sequencing; 83909 x2 capillary electrophoresis; 83912 Interpretation and report. Additional CPT code modifiers may be required for procedures performed to test for oncologic or inherited disorders.
2002398
Alport Syndrome, X-linked (COL4A5) Sequencing and Deletion/Duplication
ALPORT FGA
Methodology:
Polymerase Chain Reaction/ Sequencing/Multiplex Ligation-dependent Probe Amplification
Specimen Required: Collect: Lavender (EDTA), pink (K2EDTA), or yellow (ACD solution A or B).
CPT Code(s):
Sequencing: 83891 Isolation; 83898 x46 Amplification; 83904 x46 Sequencing; 83909 x2 capillary electrophoresis.
Del/Dup: 83896 x2 Nucleic Acid Probes; 83898 x2 Amplification; 83914 x2 Extension; 83909 x2 Capillary Electrophoresis; 83912 Interpretation
and report - Additional CPT code modifiers may be required for procedures performed to test for oncologic or inherited disorders.
0090010
Alprazolam
ALPR
Methodology:
Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Specimen Required: Collect: Plain red. Also acceptable: Lavender (K2 or K3EDTA) or pink (K2EDTA).
Specimen Preparation: Separate serum or plasma from cells within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard
Unacceptable Conditions: Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution).
CPT Code(s):
80154
0099266
Methodology:
Aluminum, Serum
AL S
Quantitative Inductively Coupled Plasma-Mass Spectrometry
Diet, medication, and nutritional supplements may introduce interfering substances. Patient should be encouraged to
discontinue nutritional supplements, vitamins, minerals, and non-essential over-the-counter medications (upon the advice of their physician).
Specimen Required: Collect: Royal blue (no additives) or Royal blue (EDTA)
Specimen Preparation: Centrifuge; do not allow serum or plasma to remain on cells. Transfer 2 mL serum or plasma to an ARUP Trace ElementFree Transport Tube (ARUP supply #43116). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800)
522-2787. (Min: 0.5 mL)
Unacceptable Conditions: Separator tubes. Specimens that are not separated from the red cells or clot within 6 hours.
Stability: If the specimen is drawn and stored in the appropriate container, the trace element values do not change with time.
CPT Code(s):
82108
0099408
Methodology:
Aluminum, Urine
AL U
Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to
discontinue nutritional supplements, vitamins, minerals, and non-essential over-the-counter medications (upon the advice of their physician). High
concentrations of iodine may interfere with elemental testing. Abstinence from iodine-containing medications or contrast agents for at least 1
month prior to collecting specimens for elemental testing is recommended.
Specimen Required: Collect: 24-hour or random urine collection. Specimen must be collected in a plastic container. ARUP studies indicate that refrigeration of
urine alone, during and after collection, preserves specimens adequately, if tested within 14 days of collection.
Specimen Preparation: Transfer an 8 mL aliquot from a well-mixed collection to ARUP Trace Element-Free Transport Tubes (ARUP supply
#43116). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 1 mL) Record
total volume and collection time interval on transport tube and on test request form.
Unacceptable Conditions: Urine collected within 48 hours after administration of a gadolinium (Gd) containing contrast media (may occur with
MRI studies). Acid preserved urine.
Stability: Ambient: 1 week; Refrigerated: 2 weeks; Frozen: 1 year
CPT Code(s):
82108
Page | 80
0091195
Amantadine (Symmetrel®), Serum or Plasma
Methodology:
Gas Chromatography
Specimen Required: Collect: Plain red, gray (sodium fluoride/potassium oxalate), green (sodium heparin), lavender (EDTA), or pink (K2EDTA).
Stability: Ambient: 1 week; Refrigerated: 2 weeks; Frozen: 5 months
CPT Code(s):
80299
AMANTADIN
0091162
Amantadine (Symmetrel®), Urine
Methodology:
Gas Chromatography
CPT Code(s):
80299
AMANTAD U
0090295
Methodology:
Amikacin, Peak Level
AMIKP
Immunoassay
Draw 30 minutes following completion of drug infusion.
Specimen Required: Collect: Plain red. Also acceptable: Green (sodium heparin).
Specimen Preparation: Separate serum or plasma from cells within one hour of collection. Transfer 1 mL serum or plasma to an ARUP Standard
Storage/Transport Temperature: Refrigerated. If transport is prolonged: Frozen.
Unacceptable Conditions: Specimens collected in citrate or oxalate/fluoride. Specimens exposed to repeated freeze/thaw cycles.
Stability: After separation from cells: Ambient: 4 hours; Refrigerated: 1 week; Frozen: 2 weeks
CPT Code(s):
80150
0090015
Amikacin, Random Level
AMIK
Methodology:
Immunoassay
Stability: After separation from cells: Ambient: 4 hours; Refrigerated: 1 week; Frozen: 14 days
CPT Code(s):
80150
0090300
Methodology:
Amikacin, Trough Level
AMIKT
Immunoassay
Draw 5-90 minutes before next infusion.
Stability: After separation from cells: Ambient: 4 hours; Refrigerated: 1 week; Frozen: 2 weeks
CPT Code(s):
80150
0080137
Amino Acids Quantitative, CSF
CSFAA QNT
Methodology:
Ion Exchange Chromatography
Specimen Preparation: Centrifuge CSF to separate and remove cellular material. Freeze supernatant. Transport 0.5 mL CSF. (Min: 0.3 mL)
Stability: Ambient: Unacceptable; Refrigerated: 24 hours; Frozen: 1 month
CPT Code(s):
82139
0080710
Methodology:
Amino Acids Quantitative, Plasma
AA QNT
Adults: Fasting specimen preferred.
Infants and children: Draw specimen prior to feeding or 2-3 hours after a meal.
Specimen Required: Collect: Green (sodium or lithium heparin).
Specimen Preparation: Separate plasma from cells ASAP or within 2 hours of collection. Avoid transferring buffy coat material. Transfer 0.5 mL
plasma to an ARUP Standard Transport Tube and freeze immediately. (Min: 0.25 mL)
Stability: After separation from cells: Ambient: Unacceptable; Refrigerated: 24 hours; Frozen: 1 month
CPT Code(s):
82139
0080044
Methodology:
Page | 81
Amino Acids Quantitative, Urine
UAA QNT
First morning urine preferred.
Specimen Required: Collect: Random urine. Avoid dilute urine when possible.
Specimen Preparation: Mix urine well. Transfer 8 mL aliquot of urine to ARUP Standard Transport Tubes and freeze immediately. (Min: 3 mL)
therapy), drug therapy, and family history. Biochemical Genetics Patient History Form is available on the ARUP Website or by contacting
ARUP Client Services.
CPT Code(s):
82139
0091284
Aminocaproic Acid, Serum or Plasma
Methodology:
Stability: Ambient: 1 week; Refrigerated: 2 weeks; Frozen: 1 month
CPT Code(s):
80299
0091375
Aminocaproic Acid, Urine
Methodology:
CPT Code(s):
82491
AMINOCAPR
AMINOC UR
0080103
Methodology:
Aminolevulinic Acid (ALA), Urine
ALA U
Quantitative Ion Exchange Chromatography/Spectrophotometry
Refrain from alcohol consumption 24 hours prior to collection.
Specimen Required: Collect: 24 hour or random urine. Refrigerate 24-hour specimens during collection.
Specimen Preparation: Protect from light. Transfer a 4 mL aliquot from a well-mixed 24 hour or random collection to an ARUP Amber Transport
Tube. (Min: 1.2 mL) Record total volume and collection time interval on transport tube and test request form.
Unacceptable Conditions: Body fluids other than urine.
Stability: Ambient: Unacceptable; Refrigerated: 4 days; Frozen: 1 month
CPT Code(s):
82135
0090161
Amiodarone and Metabolite
AMIOD
Methodology:
Specimen Preparation: Separate serum or plasma from cells within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Amber
Stability: After separation from cells: Ambient: 1 month; Refrigerated: 6 weeks; Frozen: 6 weeks
CPT Code(s):
80299 x2
0090158
Amitriptyline and Nortriptyline
AMIT/NORT
Methodology:
Stability: After separation from cells: Ambient: 5 days; Refrigerated: 2 weeks; Frozen: 6 months
CPT Code(s):
80152 Amitriptyline; 80182 Nortriptyline
0020043
Ammonia, Plasma
AMMON
Methodology:
Colorimetry
Specimen Required: Collect: Green (sodium or lithium heparin). Collect on ice.
Specimen Preparation: Separate plasma from cells and freeze within 15 minutes of draw time. Specimens need to be spun in a refrigerated
centrifuge. Transfer 2 mL plasma to an ARUP Standard Transport Tube. (Min: 0.25 mL)
Unacceptable Conditions: Serum or blood. Non-frozen specimens. Specimens containing oxalate or citrate
Stability: After separation from cells: Ambient: Unacceptable; Refrigerated: 2 hours; Frozen: 3 weeks (do not thaw)
CPT Code(s):
82140
0080276
Methodology:
Amniotic Bilirubin Scan
AMBIL
Amniocentesis.
Specimen Preparation: Protect from light during collection, storage, and shipment. Transfer 3 mL amniotic fluid to an ARUP Amber Transport
Tube. (Min: 2 mL)
Unacceptable Conditions: Specimens not protected from light.
Stability: If specimen is protected from light: Ambient: 48 hours; Refrigerated: 1 week; Frozen: 1 year
CPT Code(s):
82143
Page | 82
0090978
Amobarbital, Serum or Plasma
Methodology:
Gas Chromatography/Mass Spectrometry
Specimen Preparation: Transfer 2 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 1 mL)
CPT Code(s):
82205
0091500
Amobarbital, Urine
Methodology:
CPT Code(s):
82205
AMOBARB SP
AMOBARB U
0060250
Amoeba Calcofluor Stain
ACANTSTAIN
Methodology:
Qualitative Calcofluor Stain/Microscopy
Specimen Required: Collect: Corneal scrapings or vitreous fluid.
Specimen Preparation: Place corneal scrapings or vitreous fluid in 2 ml of Page's amoeba saline (ARUP supply #31917). Available online through
eSupply using ARUP Connect™ or contact Client Services at (800) 522-2787.
Unacceptable Conditions: Specimens in media or preservatives. Dry specimens.
CPT Code(s):
87206
0091236
Amoxapine and Metabolite Quantitation, Serum or Plasma
AMOXAPINE
Methodology:
Quantitative High Performance Liquid Chromatography
Specimen Preparation: Separate from cells within 2 hours. Transfer 2 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.7 mL)
CPT Code(s):
80299
0091237
Amoxapine and Metabolite Quantitation, Urine
Methodology:
Specimen Preparation: Transfer 2 mL urine to an ARUP Standard Transport Tube. (Min: 1 mL)
CPT Code(s):
80299
AMOXAPIN U
0020506
Amylase, Body Fluid
AMY-FL
Methodology:
Specimen Required: Collect: Body fluid. Also acceptable: Fluid collected in plain red or green (sodium or lithium heparin).
Specimen Preparation: Centrifuge to remove cellular material. Transfer 1 mL body fluid to an ARUP Standard Transport Tube. (Min: 0.2 mL)
Remarks: Indicate source on test request form.
Unacceptable Conditions: Breast milk and salivary fluid. Specimens too viscous to be aspirated by instrument.
Stability: After separation from cellular material: Ambient: 1 week; Refrigerated: 1 month; Frozen: 1 month
CPT Code(s):
82150
0020804
Amylase, Isoenzymes
AMYISO
Methodology:
Specimen Required: Collect: Serum separator tube or plasma separator tube. Also acceptable: Lavender (EDTA) or green (sodium or lithium heparin).
Unacceptable Conditions: Body Fluids (refer to Amylase, Body Fluid, ARUP test code 0020506). Hemolyzed specimens.
Stability: After separation from cells: Ambient: 1 week; Refrigerated: 1 month; Frozen: 1 month
CPT Code(s):
82150 Amylase, total; 82150 Amylase, pancreatic
0020013
Amylase, Serum or Plasma
AMY
Methodology:
Unacceptable Conditions: Body Fluid (refer to Amylase, Body Fluid, ARUP test code 0020506). Urine (refer to Amylase, Urine, ARUP test code
0020471). Specimens containing calcium chelating anticoagulants such as oxalates, citrates, or EDTA.
Stability: After separation from cells: Ambient: 1 week; Refrigerated: 1 month; Frozen: 1 month
CPT Code(s):
82150
Page | 83
0020471
Amylase, Urine
UAMY
Methodology:
Enzymatic
Specimen Required: Collect: 24-hour or timed urine collection with no preservatives. Refrigerate during collection.
Specimen Preparation: Mix timed urine collection well. Transfer 4 mL urine to an ARUP Standard Transport Tube. (Min: 0.5 mL) Record total
volume and collection time interval on transport tube and test request form.
Unacceptable Conditions: Specimens containing acetic acid, concentrated HCl, nitric acid or sodium carbonate.
Stability: Ambient: 2 days; Refrigerated: 10 days; Frozen: 3 weeks
CPT Code(s):
82150
0089110
Anabolic Steroids Panel
Methodology:
Qualitative Gas Chromatography/Mass Spectrometry
Specimen Preparation: Transport 40 mL urine. (Min: 12 mL)
Stability: Ambient: 1 week; Refrigerated: 1 month; Frozen: Indefinitely
CPT Code(s):
80100
ANAB
0060143
Anaerobe Culture and Gram Stain
MC ANA
Methodology:
Stain/Culture/Identification
Specimen Required: Collect: Contact the laboratory prior to collection of the specimen if consultation on collection containers or transport is needed. Aspirate, body
fluids, tissues, or material collected from areas without normal anaerobic flora.
Specimen Preparation: Place specimen immediately into anaerobe transport media (ARUP supply #16426). Available online through eSupply
using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787.
Remarks: Specimen source required. Indicate if Actinomyces is suspected.
Unacceptable Conditions: Specimen from site with normal anaerobic flora. Aerobic conditions.
Stability: Ambient: 48 hour; Refrigerated: Unacceptable; Frozen: Unacceptable
CPT Code(s):
87075 Culture; identification and susceptibility CPT codes may vary based on method.
0060164
Methodology:
Anaerobic Organism Identification
MC ANAID
Identification
Identification methods may include macrobroth dilution or microbroth dilution.
Specimen Required: Collect: Actively growing organism in pure culture.
Specimen Preparation: Transport sealed container with pure culture on agar slant in anaerobic transport pouch or on a swab in anaerobic transport
media. Place each specimen in an individually sealed bag.
CPT Code(s):
87076 and/or 87153; CPT codes for identification vary based upon method.
0060198
Methodology:
Anaerobic Organism Identification with Reflex to Susceptibility
MC ANAIS
Identification
Identification methods may include macrobroth dilution or microbroth dilution.
Specimen Required: Collect: Actively growing organism, in pure culture
CPT Code(s):
87076 and/or 87153; CPT codes for identification and susceptibility tests vary based upon method.
0097303
Anaplasma phagocytophilum (HGA) Antibodies, IgG & IgM
Methodology:
Semi-Quantitative Indirect Fluorescent Antibody
Unacceptable Conditions: Bacterially contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid specimens.
CPT Code(s):
86666 x2
HGE G/M
0097317
Anaplasma phagocytophilum (HGA) Antibody, IgG
Methodology:
Unacceptable Conditions: Bacterially contaminated, heat inactivated, hemolyzed, icteric, lipemic, or turbid specimens.
CPT Code(s):
86666
HGE IGG
0097318
Anaplasma phagocytophilum (HGA) Antibody, IgM
Methodology:
HGE IGM
Page | 84
CPT Code(s):
Unacceptable Conditions: Bacterially contaminated, heat inactivated, hemolyzed, icteric, lipemic, or turbid specimens.
86666
2003439
Anaplastic Lymphoma Kinase 1 (ALK-1) by Immunohistochemistry
ALK1 IHC
Methodology:
CPT Code(s):
88342
2006480
ANCA-Associated Vasculitis Profile (ANCA/MPO/PR-3) with Reflex to ANCA Titer
ANCA PRO
Methodology:
Semi-Quantitative Indirect Fluorescent Antibody/Semi-Quantitative Multiplex Bead Assay
Tube. (Min: 0.5 mL)
Unacceptable Conditions: CSF, plasma, urine, or other body fluids. Contaminated, hemolyzed, or severely lipemic specimens.
CPT Code(s):
83516 MPO; 83516 PR-3; 86255 ANCA; if reflexed, add 86256 ANCA titer
2005419
Androstanediol Glucuronide Quantitative
ANDRO GLUC
Methodology:
Quantitative Radioimmunoassay/Chromatography
Specimen Preparation: Separate serum from cells within 1 hour. Transfer 2 mL serum to an ARUP Standard Transport Tube and freeze
immediately. (Min: 0.7 mL)
CPT Code(s):
82154
2001638
Methodology:
Androstenedione
ANDRO TMS
Specimen should be collected between 6-10 a.m.
Specimen Preparation: Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.3 mL) Also acceptable: EDTA plasma.
Stability: After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 6 months
CPT Code(s):
82157
0040208
Aneuploidy Panel by FISH
FISHANEU
Methodology:
Specimen Required: Collect: Green (sodium heparin).
Specimen Preparation: Do not freeze or expose to extreme temperatures. Transport 5 mL whole blood. (Min: 1 mL) Specimen and completed
test request form, including clinical indication, must be received within 48 hours of collection.
Remarks: This test must be ordered using Cytogenetic test request form #43097 or through your ARUP interface. Submit the Patient History for
Cytogenetic (Chromosome) Studies with the electronic packing list (available at http://www.aruplab.com/genetics/forms.php).
Unacceptable Conditions: Frozen specimens. Clotted specimens.
CPT Code(s):
88271 x5 DNA probe; 88275 x5 Interphase in situ hybridization 100-300 each; 88291 Interpretation and report - Additional CPT code modifiers
may be required for procedures performed to test for oncologic or inherited disorders.
2005077
Angelman Syndrome and Prader-Willi Syndrome by Methylation
AS PWS
Methodology:
Methylation Sensitive Polymerase Chain Reaction/Fluorescence Monitoring
CPT Code(s):
83891 Isolation; 83898 Amplification; 83912 Interpretation and report - Additional CPT code modifiers may be required for procedures
performed to test for oncologic or inherited disorders.
2005564
Angelman Syndrome (UBE3A) Sequencing
UBE3A FGS
Methodology:
Specimen Required: Collect: Lavender (EDTA), pink (K2EDTA) or yellow (ACD Solution A or B).
CPT Code(s):
Sequencing: 83891 Isolation; 83898 x16 Amplification; 83904 x16 Sequencing; 83909 Capillary electrophoresis; 83912 Interpretation and report Additional CPT code modifiers may be required for procedures performed to test for oncologic or inherited disorders.
Page | 85
0098771
Angiotensin II
ANGIO II
Methodology:
Immunoassay
Specimen Preparation: Separate plasma from cells ASAP or within 2 hours of collection. Keep cold during centrifugation. Transfer 1 mL plasma
to an ARUP Standard Transport Tube. (Min: 0.3 mL)
Unacceptable Conditions: Received room temperature or refrigerated. Hemolyzed specimens.
Stability: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 1 month
CPT Code(s):
82163
0098974
Angiotensin Converting Enzyme, CSF
Methodology:
Specimen Preparation: Transfer 1 mL CSF to an ARUP Standard Transport Tube. (Min: 0.3 mL)
Unacceptable Conditions: Hemolyzed or xanthochromic specimens.
Stability: Ambient: 4 hours; Refrigerated: 1 week; Frozen: 6 months
CPT Code(s):
82164
ACE CSF
0080001
Angiotensin Converting Enzyme, Serum
ACE
Methodology:
Unacceptable Conditions: EDTA or heparin plasma. CSF (refer to Angiotensin Converting Enzyme, CSF test code 0098974)
CPT Code(s):
82164
0081335
1,5 Anhydroglucitol (GlycoMark®)
GLYCO MARK
Methodology:
Specimen Required: Collect: Serum separator tube or lavender (EDTA).
Stability: After separation from cells: Ambient: 1 week; Refrigerated: 1 week; Frozen: 1 month
CPT Code(s):
84378
0050392
Ankylosing Spondylitis (HLA-B27) Genotyping
HLAB27 PCR
Methodology:
CPT Code(s):
83891 Isolation; 83898 Amplification; 83912 Interpretation and report. Additional CPT code modifiers may be required for procedures performed
to test for oncologic or inherited disorders.
2003463
Anti-Human Epithelial Antigen, Ber-EP4 by Immunohistochemistry
BEREP4 IHC
Methodology:
CPT Code(s):
88342
2003126
Anti-IgA Antibody
Methodology:
Specimen Preparation: Transfer 1 mL serum to an ARUP standard Transport Tube. (Min: 0.5 mL)
Unacceptable Conditions:
CPT Code(s):
83520
Page | 86
ANTI IGA
2002656
Anti-Mullerian Hormone
Methodology:
Specimen Preparation: Transport 0.5 mL serum. (Min: 0.2 mL)
Storage/Transport Temperature: Critical Frozen.
Unacceptable Conditions: Room temperature specimens. Hemolyzed or lipemic specimens.
Stability: Ambient: Unacceptable; Refrigerated: 48 hours; Frozen: 30 days (avoid repeated freeze/thaw cycles)
CPT Code(s):
83520
AMH
0050811
Anti-Neutrophil Cytoplasmic Antibody, IgG
ANCA IFA
Methodology:
Unacceptable Conditions: Plasma, urine, or other body fluids. Contaminated, hemolyzed, or severely lipemic specimens.
CPT Code(s):
86255 ANCA; if positive, add 86256 ANCA titer
0050080
Anti-Nuclear Antibodies (ANA), IgG by ELISA with Reflex to ANA, IgG by IFA
ANA
Methodology:
Qualitative Enzyme-Linked Immunosorbent Assay/Semi-Quantitative Indirect Fluorescent Antibody
Tube. (Min: 0.3 mL)
Unacceptable Conditions: Plasma or urine. Contaminated, grossly hemolyzed, heat-inactivated, severely lipemic specimens or inclusion of fibrin
clots.
CPT Code(s):
86038 ANA; if reflexed, add 86039 ANA titer
0060845
Antibiotic Level, Aztreonam
ML AZTREO
Methodology:
Quantitative Bioassay
Specimen Preparation: Aseptically remove 2 mL serum to a sterile tube (ARUP supply #43115) and freeze. Available online through eSupply
using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 1 mL).
Remarks: Required information includes: time and date of collection, time of last dose, and list of all antibiotics that the patient is receiving or has
received in the past 48 hours.
CPT Code(s):
80299
2004886
Antibiotic Level, Ceftazidime
ML CEFTAZ
Methodology:
Bioassay
using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 1 mL)
Stability: Ambient: 2 hours; Refrigerated: 24 hours (local clients only); Frozen: 1 week
CPT Code(s):
80299
0060844
Antibiotic Level, Meropenem
ML MERO
Methodology:
Storage/Transport Temperature: Frozen
CPT Code(s):
80299
0060843
Antibiotic Level, Nafcillin
ML NAF
Methodology:
CPT Code(s):
80299
Page | 87
0060842
Antibiotic Level, Piperacillin
ML PIP
Methodology:
CPT Code(s):
80299
0060841
Antibiotic Level, Ticarcillin
ML TICAR
Methodology:
CPT Code(s):
80299
0010004
Antibody Detection, RBC
Methodology:
Hemagglutination
Specimen Preparation: Do not freeze.
Transport 10 mL whole blood (plain red) (Min: 7 mL). AND 5 mL whole blood (EDTA) (Min: 3 mL).
Pediatric: Transport 1 mL whole blood (plain red). AND 0.5 mL whole blood (EDTA).
Remarks:
CPT Code(s):
86850
IRL-ABSC
0013003
Antibody ID Package (IRL)
IRL-AB PKG
Methodology:
Hemagglutination
Specimen Preparation: Do not freeze. Transport 10 mL whole blood (plain red) AND 10 mL whole blood (EDTA). (Min: 7 mL plain red AND 5
mL EDTA).
Storage/Transport Temperature: Refrigerated. Deliver to lab immediately.
Remarks:
CPT Code(s):
86900 ABO; 86901 Rh; 86906 Rh Phen; 86880 DC; 86870 x3 ABID
0013005
Antibody Identification, RBC (Prenatal Only)
IRL-ABID
Methodology:
Hemagglutination
Specimen Required: Collect: Plain red AND lavender (EDTA), pink (K2EDTA) or yellow (ACD solution).
Specimen Preparation: Do not freeze. Transport 10 mL whole blood (plain red) (Min: 7 mL). AND 5 mL whole blood (EDTA) (Min: 3 mL) Also
acceptable: Plasma, serum, or clot.
Remarks:
CPT Code(s):
86900 ABO; 86901 Rh; 86880 DC; 86870 ABID; 86906 Rh Phenotyping
0010020
Antibody Screen RBC with Reflex to Identification
ABSC-R
Methodology:
Solid Phase
Remarks:
Unacceptable Conditions: Plasma Separator Tubes.
CPT Code(s):
86850 Ab Screen; if reflexed as part of Prenatal Reflexive Panel (0095044): add 86870 Ab Identification; 86880 Direct Coombs; and 86906 Rh
Phenotype
Page | 88
0013006
Antibody Titer
Methodology:
Hemagglutination
Remarks:
CPT Code(s):
86886
IRL-ABTR1
0090601
Antidepressant Panel Quantitation, Serum or Plasma
ANTIDEP
Methodology:
Quantitative Gas Chromatography/Gas Chromatography-Mass Spectrometry
Stability: Ambient: 1 week; Refrigerated: 2 weeks; Frozen: 2 weeks
CPT Code(s):
82542
0096048
Antidepressant Panel Quantitation, Urine
Methodology:
Quantitative Gas Chromatography/Gas Chromatography-Mass Spectrometry
Storage/Transport Temperature: 2 mL urine at 2-8°C. (Min: 0.7 mL) Submit specimen in an ARUP Standard Transport Tube.
Stability: Ambient: 1 week; Refrigerated: 11 days; Frozen: 2 weeks
CPT Code(s):
82542
ANTIDEP U
0060846
Antifungal Level, 5-Fluorocytosine (5-FC)
ML 5-FLUOR
Methodology:
CPT Code(s):
80299
Antigen Testing, AHG - Specify Individual RBC Antigen
0013298
Methodology:
Hemagglutination
Specimen Required: Collect: Plain red. Also acceptable: Lavender (EDTA) or pink (K2EDTA).
Pediatric: Transport 0.5 mL whole blood.
Remarks:
CPT Code(s):
86905 each antigen
IRL-AG/AHG
0013297
Antigen Testing, Direct - Specify Individual RBC Antigen
Methodology:
Hemagglutination
Transport 7 mL whole blood.
Remarks:
CPT Code(s):
86905 each antigen
IRL-AG/DIR
0013020
Antigen Testing, RBC Phenotype Extended
Methodology:
Hemagglutination
Transport 7 mL whole blood (plain red) OR 5 mL whole blood (EDTA).
Remarks:
CPT Code(s):
86905 x7. Other antigen: add 86905 for each additional antigen not listed above
IRL-EXPHEN
0013019
Antigen Testing, Rh Phenotype
Methodology:
Hemagglutination
Specimen Preparation: Do not freeze. Transport 7 mL whole blood (plain red) OR 5 mL whole blood (EDTA).
IRL-RHPHEN
Page | 89
CPT Code(s):
Remarks:
Unacceptable Conditions: Serum or plasma separator tubes.
86906
0092103
Antimicrobial Level - Amphotericin B by HPLC
AMPHO B
Methodology:
Specimen Preparation: Protect from light. Transfer 2 mL serum to an ARUP Amber Transport Tube. (Min: 0.5 mL)
Unacceptable Conditions: Thawed specimens. Specimens not protected from light. Serum separator tubes.
CPT Code(s):
80299
0099972
Methodology:
Antimicrobial Level - Capreomycin (Serum) by HPLC
CAPREOMY
Draw two hours post does and just prior to next dose.
Specimen Preparation: Freeze at -70°C ASAP. Transport 2 mL serum on dry ice. (Min: 1 mL)
Remarks: Drugs which may interfere with this assay include: Sulindac. List all other antimicrobials being used to treat the patient.
CPT Code(s):
80299
0093142
Antimicrobial Level - Doxycycline (Serum), BA
Methodology:
Remarks: List all other antimicrobials being used to treat the patient.
Unacceptable Conditions: Thawed specimens. Separator tubes.
CPT Code(s):
80299
DOXY
0099428
Antimicrobial Level - Isoniazid (Serum) by HPLC
ISONIAZID
Methodology:
Specimen Preparation: Transport 2 mL serum. (Min: 1 mL)
Remarks: Include draw time on request form. Drugs which may interfere with this assay include: Iproniazid. List all other antimicrobials being
used to treat the patient.
Unacceptable Conditions: Separator tubes. Refrigerated or room temperature specimens.
CPT Code(s):
80299
0099438
Antimicrobial Level - Rifampin (Serum), HPLC
Methodology:
Semi-Quantitative High Performance Liquid Chromatography
Specimen Preparation: Protect from light. Transport 2 mL serum. (Min: 1 mL)
Unacceptable Conditions: Serum separator tubes. Room temperature or refrigerated specimens.
CPT Code(s):
80299
RIFAMPIN
0092065
Antimicrobial Level - Streptomycin, HPLC
STP MYCIN
Methodology:
Specimen Preparation: Transfer 1 mL serum to an ARUP Standard Transport Tube (Min: 0.5 mL)
Remarks: List all other antimicrobials being used to treat the patient.
Stability: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: Indefinitely
CPT Code(s):
80299
0060217
Antimicrobial Susceptibility - AFB/Mycobacteria
Methodology:
Macrobroth Dilution/Microbroth Dilution
Specimen Required: Collect: Actively growing isolate in pure culture.
Specimen Preparation: Transfer viable organism to sealed container.
Unacceptable Conditions: Mixed cultures or non-viable organisms. Organisms submitted on an agar plate.
0060347
Methodology:
Page | 90
Antimicrobial Susceptibility - AFB/Mycobacterium tuberculosis Primary Panel
Broth Macrodilution
MA AFB
MA MTBPRIM
Specimen Required: Collect: Actively growing isolate of Mycobacterium tuberculosis in pure culture.
Specimen Preparation: Transport sealed container with pure culture on solid or liquid media. Place each specimen in an individually sealed bag.
Unacceptable Conditions: Mixed cultures or non-viable organisms. Organisms submitted on agar plate.
Stability: Ambient: 2 weeks; Refrigerated: 2 weeks; Frozen: Unacceptable
CPT Code(s):
87188 x4
0060202
Antimicrobial Susceptibility - Anaerobe
MA ANA
Methodology:
Broth Microdilution
Specimen Required: Collect: Actively growing organism in pure culture.
Unacceptable Conditions: Aerobic conditions. Mixed cultures or non-viable organisms.
CPT Code(s):
87186
0060204
Antimicrobial Susceptibility - Bactericidal Assay
MA BCT
Methodology:
Broth Microdilution
Specimen Required: Collect: Actively growing isolate in pure culture AND serum or body fluid. Collect using aseptic technique.
Specimen Preparation: Organism: Transport sealed container with pure culture on agar slant or in bacterial transport media. Place each specimen
in an individually sealed bag.
AND Serum or Body Fluid: Transfer 2 mL serum or body fluid to a sterile container and freeze. (Min: 1 mL)
Storage/Transport Temperature: Organism: Room temperature.
Serum or Body Fluid: Frozen.
Remarks: A list of all antibiotics that the patient is receiving or has received in the past 48 hours must be provided (this information is essential for
performing this assay; missing information may cause delays in turnaround time).
Stability: Organism: Ambient: 1 week; Refrigerated: Unacceptable; Frozen: Unacceptable
Serum or Body Fluid: Ambient: 2 hours; Refrigerated: 24 hours; Frozen: 1 week
CPT Code(s):
87197
2001503
Antimicrobial Susceptibility - Carbapenem Resistance
MA KPC
Methodology:
Disk Diffusion
Specimen Required: Collect: Actively growing Enterobacteriaceae species in pure culture.
Specimen Preparation: Transport sealed container with pure culture on agar slant or in bacterial transport media. Place each specimen in an
Remarks: Isolate identification required.
Stability: Ambient: 1 week; Refrigerated: 48 hours; Frozen: Unacceptable
CPT Code(s):
87184
0060059
Antimicrobial Susceptibility - D-Test (Macrolide, Lincosamide, Streptogramin Resistance)
MA DTEST
Methodology:
Disk Diffusion
Specimen Required: Collect: Actively growing Staphylococcus species or beta-hemolytic Streptococcus species in pure culture.
CPT Code(s):
87184
0060706
Antimicrobial Susceptibility - Enterobacteriaceae
MA ENTER
Methodology:
Automated Broth Microdilution
Remarks: Isolate identification and specimen source required.
CPT Code(s):
87186
0060708
Antimicrobial Susceptibility - Enterococcus
MA ENTERO
Methodology:
CPT Code(s):
87186
Page | 91
0063999
Antimicrobial Susceptibility - Extended Spectrum Beta Lactamase
MA ESBL
Methodology:
Disk Diffusion
Specimen Required: Collect: Actively growing E. coli, Klebsiella species, or Proteus mirabilis in pure culture.
Remarks: Isolate identification and specimen source required. Proteus mirabilis is tested only when isolated from a significant source (e.g.,
blood).
CPT Code(s):
87184
0060345
Antimicrobial Susceptibility - Fastidious Organism
MA FAST
Methodology:
Broth Microdilution
CPT Code(s):
87186
0060346
Antimicrobial Susceptibility - Gram Positive Rod
MA GPR
Methodology:
Broth Microdilution
CPT Code(s):
87186
0060211
Antimicrobial Susceptibility - mecA Gene by PCR
MA MEC
Methodology:
Qualitative Polymerase Chain Reaction
Specimen Required: Collect: Actively growing Staphylococcus aureus or coagulase-negative Staphylococcus, in pure culture.
CPT Code(s):
87641
0060201
Antimicrobial Susceptibility - MIC, Individual
MA MIC
Methodology:
Gradient Diffusion/Broth Microdilution
Specimen Preparation: Transport sealed container with pure culture on agar slant or in bacterial transport media. Place each specimen in
Remarks: Isolate identification and specimen source required. Individual antibiotics must be specified.
CPT Code(s):
87181 Gradient dilution or 87186 Broth dilution
0060203
Antimicrobial Susceptibility - MIC/MBC
MA MBC
Methodology:
Broth Microdilution
Specimen Preparation: Transport sealed container with pure culture on agar slant or in bacterial transport media. Place each specimen in
Remarks: Isolate identification and specimen source required. Individual antibiotics must be specified.
CPT Code(s):
87186 MIC; 87187 MBC
Page | 92
0060227
Antimicrobial Susceptibility - Mould Susceptibility
MA MOULD
Methodology:
Broth Microdilution
Specimen Required: Collect: Actively growing mould in pure culture.
Specimen Preparation: Transport sealed container with pure culture on fungal medium slant. Place each specimen in an individually sealed bag.
Unacceptable Conditions: Mixed cultures or non-viable moulds. Agar plates.
CPT Code(s):
87186
0060193
Antimicrobial Susceptibility - Nocardia
MA NOC
Methodology:
Broth Microdilution
Specimen Required: Collect: Actively growing Nocardia isolate in pure culture.
Specimen Preparation: Transport sealed container with isolate in pure culture on agar slant. Place each specimen in individually sealed bag.
Stability: Ambient: 1 month; Refrigerated: 2 weeks; Frozen: Unacceptable
CPT Code(s):
87186
0060216
Antimicrobial Susceptibility - Nonfermenter
Methodology:
Broth Microdilution
Specimen Preparation: Transport sealed container with pure culture on agar slant. Place each specimen in individually sealed bag.
CPT Code(s):
87186
MA NF
0060707
Antimicrobial Susceptibility - Staphylococcus
MA STAPH
Methodology:
Specimen Preparation: Transport sealed container with pure culture on agar slant. Place each specimen in an individually sealed bag.
CPT Code(s):
87186
0060221
Antimicrobial Susceptibility - Streptococcus pneumoniae
MA SPN
Methodology:
Broth Microdilution
Specimen Preparation: Transport sealed container with pure culture on agar slant. Place each specimen in an individually sealed bag.
CPT Code(s):
87186
0060222
Antimicrobial Susceptibility - Viridans Streptococcus
Methodology:
Broth Microdilution
CPT Code(s):
87186
MA VIRS
0060235
Antimicrobial Susceptibility - Yeast Susceptibility
Methodology:
Broth Microdilution
Stability: Ambient: 1 week; Refrigerated: 2 weeks; Frozen: Unacceptable
CPT Code(s):
87186
MA YST
0060200
Antimicrobial Susceptibility - Not Otherwise Specified
MA SENS
Methodology:
Broth Microdilution/Disk Diffusion/Gradient Diffusion
Page | 93
CPT Code(s):
CPT codes may vary based on method.
0099007
Methodology:
Antimony, Blood
ANT B
Specimen Required: Collect: Royal blue (K2EDTA or Na2EDTA).
Specimen Preparation: Transport 7 mL whole blood in the original collection tube. (Min: 0.5 mL)
Unacceptable Conditions: Heparin anticoagulant. Frozen specimens.
CPT Code(s):
83018
0099409
Methodology:
Antimony, Urine
ANT U
Storage/Transport Temperature: Refrigerated. Also acceptable: Room Temperature or frozen.
CPT Code(s):
83018
2002068
Anti-Neutrophil Cytoplasmic Antibody with Reflex to Titer and MPO/PR-3 Antibodies
ANCA PN
Methodology:
Semi-Quantitative Indirect Fluorescent Antibody/Semi-Quantitative Multiplex Bead Assay
Tube. (Min: 0.5 mL)
Unacceptable Conditions: CSF, plasma, urine, or other body fluids. Contaminated, hemolyzed, or severely lipemic specimens.
CPT Code(s):
86255 ANCA; if reflexed, add 86256 ANCA titer, 83516 MPO and 83516 PR-3
0050317
Anti-Nuclear Antibodies (ANA), IgG by ELISA with Reflexes to ANA, IgG by IFA and to dsDNA, RNP, Smith,
ANA REF
SSA, and SSB Antibodies, IgG
Methodology:
Qualitative Enzyme-Linked Immunosorbent Assay/Semi-Quantitative Indirect Fluorescent Antibody/Semi-Quantitative Multiplex Bead Assay
Tube. (Min: 0.6 mL)
Unacceptable Conditions: Non-serum specimens. Contaminated, grossly hemolyzed, heat-inactivated, severely lipemic, specimens or inclusion of
fibrin clots.
CPT Code(s):
86038 ANA; if reflexed, add 86039 ANA titer; if reflexed add 86235 RNP and 86235 Smith and 86235 SSA and 86235 SSB and 86225 dsDNA;
if dsDNA reflexed, add 86256 dsDNA titer.
2003222
Antiphospholipid Syndrome Reflexive Panel
PHOS SYN
Methodology:
Clotting/Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Specimen Required: Collect: Lt. blue (sodium citrate) for Lupus Anticoagulant Reflexive Panel (refer to the Specimen Handling at aruplab.com for
hemostasis/thrombosis specimens handling guidelines) AND serum separator tube for cardiolipin and beta-2 glycoprotein antibodies.
Specimen Preparation: Separate platelet-poor plasma and serum from cells within 10 minutes of draw. Transport 2 mL plasma (Min: 1 mL) AND
1 mL serum (Min: 0.6 mL).
Storage/Transport Temperature: Plasma: CRITICAL FROZEN. Separate specimens must be submitted when mulitiple tests are ordered.
Serum: Refrigerated.
Unacceptable Conditions: For Lupus Anticoagulant Reflexive Panel (Plasma): Serum and non-sodium citrate plasma.
For cardiolipin and beta-2 glycoprotein antibodies (Serum): Plasma and other body fluids, heat-inactivated, hemolyzed, lipemic, or contaminated
specimens.
Stability: For Lupus Anticoagulant Reflexive Panel (Plasma): Ambient: 4 hours; Refrigerated: 24 hours; Frozen: 1 week;
For cardiolipin and beta-2 glycoprotein antibodies (Serum): Ambient: 48 hours; Refrigerated: 2 weeks; Frozen 1 year (avoid repeated freeze/thaw
cycles).
CPT Code(s):
Anti-Cardiolipin Antibody G/M: 86147 x2; Beta-2 Glycoprotein I, G/M: 86146 x2; 85610 Prothrombin time (PT); 85730 Partial Thromboplastin
Time (PTT); 85613 dRVVT. If PTT is abnormal, add 85670 Thrombin Time. If Thrombin time is abnormal, add 85635 Reptilase Time. If
Reptilase Time is normal, add PTT Heparin Neutralization 85730 and 85525. If PTT Heparin Neutralization is abnormal, add 85732 PTT 1:1 mix.
If PTT 1:1 mix is abnormal, add 85597 Platelet neutralization procedure (PNP). If dRVVT is abnormal, add 85613 dRVVT 1:1 mix. If dRVVT
1:1 mix is abnormal, perform 85613 dRVVT confirmation. If PNP and dRVVT conf are normal, add 85598 Hexagonal Phospholipid
Neutralization.
0030015
Methodology:
Page | 94
Antithrombin, Antigen
Microlatex Particle-Mediated Immunoassay
AT3AG
Specimen Preparation: Transfer 1 mL platelet-poor plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Remarks:
Unacceptable Conditions: Serum. Hemolyzed specimens.
Stability: Ambient: 8 hours; Refrigerated: 8 hours; Frozen: 1 month
CPT Code(s):
85301
0030010
Antithrombin, Enzymatic (Activity)
Methodology:
Chromogenic Assay
Specimen Preparation: Transfer 1.5 mL platelet-poor plasma to an ARUP Standard Transport Tube. (Min: 1 mL)
Remarks:
CPT Code(s):
85300
AT3
0030370
Antithrombin Panel
AT3 PAN
Methodology:
Chromogenic Assay/Microlatex Particle-Mediated Immunoassay
Storage/Transport Temperature: CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered
CPT Code(s):
85300 AT III; 85301 AT III Ag
2006546
Aortopathy Deletion/Duplication, 10 Genes
Methodology:
Exonic Oligonucleotide-based CGH Microarray
Specimen Required: Collect: Lavender (EDTA) or yellow (ACD Solution A or B). Peripheral blood required.
Remarks: Submit the Patient History Form for Aortopathy Disorders with the Electronic Packing List.
CPT Code(s):
83891 Isolation; 88386 Array-based evaluation of multiple molecular probes; 251 through 500
AORT DD
2006540
Aortopathy Panel, Sequencing and Deletion/Duplication, 10 Genes
AORT PANEL
Methodology:
Massive Parallel Sequencing/Exonic Oligonucleotide-based CGH Microarray
CPT Code(s):
83891 Isolation; 83909 x3 Capillary electrophoresis; 83898 x3 Amplification; 83904 x10 Sequencing; 88386 Array-based evaluation of multiple
molecular probes; 251 through 500; 83912 Interpretation and report.
2006617
Aortopathy Sequencing, 10 Genes
AORT SEQ
Methodology:
Massive Parallel Sequencing
CPT Code(s):
83891 Isolation; 83909 x3 Capillary electrophoresis; 83898 x3 Amplification; 83904 x10 Sequencing; 83912 Interpretation and report.
0030127
APC Resistance Profile
APC RST
Methodology:
Clotting
Specimen Preparation: Transfer 1.5 mL platelet-poor plasma to an ARUP Standard Transport Tube. (Min: 1 mL)
Stability: Ambient: 4 hours; Refrigerated: 4 hours; Frozen: 2 weeks
CPT Code(s):
85307
0030192
APC Resistance Profile with Reflex to Factor V Leiden
APC R
Methodology:
Clotting/Polymerase Chain Reaction/Fluorescence Monitoring
Specimen Required: Collect: Lt. blue (sodium citrate) AND lavender (EDTA), pink (K2EDTA), or yellow (ACD Solution A or B). Refer to Specimen Handling at
aruplab.com for hemostasis/thrombosis specimen handling guidelines.
Specimen Preparation: Transport 1.5 mL platelet-poor plasma AND 3 mL whole blood. (Min: 1 mL/each)
Storage/Transport Temperature: Plasma: Frozen. Whole Blood: Refrigerated.
Unacceptable Conditions: Plasma: Non-frozen specimens.
Stability: Plasma: Ambient: 4 hours; Refrigerated: Unacceptable; Frozen at -20°C: 3 months; Frozen at -70°C: 6 months
Whole Blood: Ambient: 72 hours; Refrigerated: 1 week; Frozen: Unacceptable
CPT Code(s):
85307 APC; if reflexed, add 83891 Isolation; 83896 Nucleic acid probes; 83898 Amplification; 83912 Interpretation and report; - Additional CPT
code modifiers may be required for procedures performed to test for oncologic or inherited disorders.
0050030
Methodology:
Page | 95
Apolipoprotein A-1
Freshly drawn fasting specimen.
APO A-1
Tube. (Min: 0.5 mL)
Remarks: Separate serum from cells ASAP.
CPT Code(s):
82172
0050029
Methodology:
Apolipoprotein B
APO B-100
Fasting specimen.
Tube. (Min: 0.5 mL)
CPT Code(s):
82172
0050028
Methodology:
Apolipoprotein B/A Ratio
APO B/A
Fasting specimen recommended.
CPT Code(s):
82172 Apolipoprotein, B; 82172 Apolipoprotein, A-1
0055654
Apolipoprotein B (APOB) Mutation Detection
APO B
Methodology:
CPT Code(s):
83891 Isolation; 83898 Amplification; 83896 x2 Nucleic acid probes; 83912 Interpretation and report - Additional CPT code modifiers may be
0055566
Apolipoprotein E (APOE) 2 Mutations, Cardiovascular Risk
APO E
Methodology:
CPT Code(s):
83891 Isolation; 83898 Amplification; 83896 x2 Nucleic acid probes; 83912 Interpretation and report - Additional CPT code modifiers may be
0091000
Aprobarbital, Serum or Plasma
Methodology:
Gas Chromatography
Stability: Ambient: 2 weeks; Refrigerated: 2 weeks; Frozen: 6 months
CPT Code(s):
82205
0091176
Aprobarbital, Urine
Methodology:
Gas Chromatography
CPT Code(s):
82205
APROBAR SP
APROBAR U
2003036
Aquaporin-4 Receptor Antibody
AQP4
Methodology:
Tube. (Min: 0.3 mL)
Unacceptable Conditions: CSF, amniotic fluid, ocular fluid peritoneal fluid, synovial fluid, or plasma. Contaminated, hemolyzed, icteric, or
lipemic specimens.
Stability: After separation from cells: Ambient: 72 hours; Refrigerated: 2 weeks; Frozen: 1 month (avoid repeated freeze/thaw cycles)
CPT Code(s):
83516
Page | 96
2001597
Arbovirus Antibodies, IgG & IgM, CSF
ARBOCSF GM
Methodology:
Semi-Quantitative Indirect Fluorescent Antibody/Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Stability: Ambient: 8 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
CPT Code(s):
86651 x2 Encephalitis, California (La Crosse); 86652 x2 Encephalitis, Eastern Equine; 86653 x2 Encephalitis, St. Louis; 86654 x2 Encephalitis,
Western Equine; 86789 West Nile Virus IgG; 86788 West Nile Virus IgM
2001594
Arbovirus Antibodies, IgG and IgM, Serum
ARBOSER GM
Methodology:
Specimen Required: Collect: Serum separator tube. Also acceptable: Plain red.
Tube. (Min: 0.2 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of acute specimens.
Mark specimens plainly as "acute" or "convalescent."
CPT Code(s):
86651 x2 Encephalitis, California (La Crosse); 86652 x2 Encephalitis, Eastern Equine; 86653 x2 Encephalitis, St. Louis; 86654 x2 Encephalitis,
Western Equine; 86789 West Nile Virus IgG; 86788 West Nile Virus IgM
2001596
Arbovirus Antibodies, IgG, CSF
ARBO CSF G
Methodology:
Unacceptable Conditions: Plasma. Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimens.
CPT Code(s):
86651 Encephalitis, California (La Crosse); 86652 Encephalitis, Eastern Equine; 86653 Encephalitis, St. Louis; 86654 Encephalitis, Western
Equine; 86789 West Nile Virus
2001593
Arbovirus Antibodies, IgG, Serum
ARBO SER G
Methodology:
Unacceptable Conditions: Contaminated, hemolyzed, or severely lipemic, specimens.
CPT Code(s):
Equine; 86789 West Nile Virus IgG
2001595
Arbovirus Antibodies, IgM, CSF
ARBO CSF M
Methodology:
Unacceptable Conditions: Contaminated, heat-inactivated , or hemolyzed specimens.
CPT Code(s):
86651 Encephalitis, California (La Crosse); 86652 Encephalitis, Eastern equine; 86653 Encephalitis, Saint Louis; 86654 Encephalitis, Western
equine; 86788 West Nile Virus
2001592
Arbovirus Antibodies, IgM, Serum
ARBO SER M
Methodology:
Unacceptable Conditions: Plasma. Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimens.
CPT Code(s):
Equine; 86788 West Nile Virus
0070027
Arginine Vasopressin Hormone
AVH PLASMA
Methodology:
Specimen Preparation: Separate plasma from cells ASAP or within 2 hours of collection. Transfer 6 mL plasma to ARUP Standard Transport
Tubes and freeze immediately. (Min: 2.5 mL)
Unacceptable Conditions: Non-frozen specimens.
CPT Code(s):
84588
Page | 97
2003178
Aripiprazole, Serum or Plasma
ARIPIPRAZ
Methodology:
Specimen Preparation: Separate from cells within 2 hours of draw. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min:
0.5 mL)
CPT Code(s):
83789
0091580
Methodology:
Aromatic Primary Amines, Urine
Spectrophotometry
Collect at end of shift.
Specimen Required: Collect: Urine.
CPT Code(s):
84311
AROMAT AMI
0091435
Aromatic Solvents Panel, Whole Blood
Methodology:
Specimen Required: Collect: Lavender (EDTA) or gray (potassium oxalate or sodium fluoride).
Stability: Ambient: Unacceptable; Refrigerated: 5 days; Frozen: 5 days
CPT Code(s):
84600
AROMATIC B
2006216
Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Panel, 7 Genes
ARVC PANEL
Methodology:
Remarks: Do not expose specimen to extreme temperatures. Clinical indication or reason for testing is required.
CPT Code(s):
83891 Isolation; 83900 Amplification; 83901 x51 Additional amplification; 83904 x51 Sequencing; 83909 x3 Capillary electrophoresis; 83912
Interpretation and report.
2007342
Arsenic Analysis, Hair
ARS HAIR
Methodology:
Specimen Required: Collect: Collect a pencil-thick segment of hair. Bundle, cut at roots, wrap with twist tie at root end.
Specimen Preparation: Transfer 500 mg hair to an ARUP Trace Element-Free Transport Tube (ARUP supply #43116) available online through
eSupply using ARUP Connector contact ARUP Client Services at (800) 522-2787. (Min: 500 mg)
Stability: Ambient: Undetermined Refrigerated: Undetermined Frozen: Undetermined
2007344
Arsenic Analysis, Nails
ARS NAILS
Methodology:
Quantitative Inductively Coupled Plasma/Mass Spectrometry
Specimen Required: Collect: Nails.
Specimen Preparation: Transfer 500 mg nails to an ARUP Trace Element-Free Transport Tube (ARUP supply #43116) available online through
eSupply using ARUP Connector contact ARUP Client Services at (800) 522-2787. (Min: 500 mg)
Stability: Ambient: Undetermined Refrigerated: Undetermined Frozen: Undetermined
CPT Code(s):
82175 Arsenic; 80103 Tissue preparation
0099045
Methodology:
Arsenic, Blood
ARS B
discontinue nutritional supplements, vitamins, minerals, and non-essential over-the-counter medications (upon the advice of their physician) and
avoid shellfish and seafood for 48 to 72 hours.
CPT Code(s):
82175
0090664
Methodology:
Arsenic, Fluid
ARSENIC FL
Inductively Coupled Plasma/Mass Spectrometry
Avoid seafood consumption for 48 hours prior to specimen collection.
Specimen Required: Collect: Fluid.
Specimen Preparation: Transfer 3 mL fluid to an ARUP Trace Element-Free Transport Tube (ARUP supply #43116). Available online through
eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 2 mL)
Remarks: This test can be used for arsenic in water (no drinking water).
CPT Code(s):
82175
Page | 98
0020734
Arsenic, Fractionated, Urine
AS UF
Methodology:
Quantitative High Performance Liquid Chromatography/Quantitative Inductively Coupled Plasma-Mass Spectrometry
Specimen Required: Collect: 24-hour or random urine collection. Specimen must be collected in a plastic container and should be refrigerated during collection. ARUP
studies indicate that refrigeration of urine alone, during and after collection, preserves specimens adequately if tested within 14 days of
collection.
Specimen Preparation: Transfer an 8 mL aliquot of urine from a well-mixed collection to ARUP Trace Element-Free Transport Tubes (ARUP
supply #43116). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 2 mL)
Record total volume and collection time interval on transport tube and on test request form.
CPT Code(s):
82175
0025000
Methodology:
Arsenic, Urine with Reflex to Fractionated
ARS U
Quantitative High Performance Liquid Chromatography/Quantitative Inductively Coupled Plasma-Mass Spectrometry
discontinue nutritional supplements, vitamins, minerals, nonessential over-the-counter medications (upon the advice of their physician), and avoid
shellfish and seafood for 48 to 72 hours. High concentrations of iodine may interfere with elemental testing. Abstinence from iodine-containing
medications or contrast agents for at least 1 month prior to collecting specimens for elemental testing is recommended.
Specimen Required: Collect: 24-hour or random urine collection. Specimen must be collected in a plastic container and refrigerated during collection. ARUP studies
indicate that refrigeration of urine alone, during and after collection, preserves specimens adequately if tested within 14 days of
collection.
#43116). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 2 mL)
CPT Code(s):
82175; if reflexed, add 82175
ARUP Drug Screen Cup (Point-of-Care test only)
Qualitative Competitive Immunoassay, uses CLIA-waived device
Do not open test device pouch until ready to collect specimen.
Specimen Required: Collect: Random urine. Requires 30 mL urine to use Testing Cup (NexScreen cup) provided in kit (ARUP supply #49204). Available online
through eSupply using ARUP ConnectTM or contact ARUP Client Services at (800) 522-2787. Collect directly in Testing Cup; may also use
another collection container then pour into Testing Cup.
Methodology:
CPT Code(s):
CONFIRMATION TESTING: If the result of the Testing Cup is not negative (presumptive positive) and is inconsistent with clinical
expectations and pharmacy history, it should be confirmed using a second, more-specific and quantitative technology such as LC-MS/MS or GCMS. If the patient is expected to be taking Benzodiazepines and/or Opiates/oxycodone, results should be confirmed by quantitative LC-MS/MS
regardless of the screen result. Transfer 4 mL urine from the Testing Cup into an ARUP Standard Transport Tube. Transport one tube for each test
requested.
Specimen Preparation: If specimen, control, or test devices have been stored at refrigerated temperatures, warm to room temperature (59-83 before
testing.
Unacceptable Conditions: Specimens exposed to repeated freeze/thaw cycles
Stability: Results must be read at exactly 5 minutes after urine is placed in the Testing Cup.
Stability for confirmation testing: Ambient: 1 week; Refrigerated: 1 month; Frozen: 3 years
80104; G0434 (medicare/medicaid only)
0095227
Arylsulfatase A, Urine
Methodology:
Quantitative Kinetic Colorimetry
Specimen Required: Collect: 24-hour urine. Do not use preservatives.
Specimen Preparation: Transfer 10 mL urine to ARUP Standard Transport Tubes. (Min. 5 mL)
Remarks: Indicate total volume.
Stability: Ambient: Unacceptable; Refrigerated: 2 weeks; Frozen: Unacceptable
CPT Code(s):
84311
ARYLSULF A
0051415
Ashkenazi Jewish Diseases (BLM, ASPA, IKBKAP, FANCC, GBA, MCOLN1, SMPD1, HEXA)
AJP
Methodology:
Polymerase Chain Reaction/ASPE Bead Array
CPT Code(s):
83891 Isolation; 83892 x2 Enzymatic digestion; 83900 Amplification multiplex (first two amplifications); 83901 x16 Amplification multiplex
(each additional amplification); 83914 x31 Mutation identification; 83909 Separation and identification; 83912 Interpretation and report Additional CPT code modifiers may be required for procedures performed to test for oncologic or inherited disorders.
0020007
Aspartate Aminotransferase, Serum or Plasma
Methodology:
Page | 99
AST
CPT Code(s):
Unacceptable Conditions: Specimens containing sodium fluoride/potassium oxalate, EDTA, or citrate. Hemolyzed specimens. Specimens
containing cellular material.
84450
0050101
Aspergillus Antibodies by CF and ID
ASPER PRO
Methodology:
Semi-Quantitative Complement Fixation/Qualitative Immunodiffusion
Specimen Preparation: Separate serum from cells ASAP or within 2 hours of collection. Transfer1 mL serum to an ARUP Standard Transport
Tube. (Min: 0.2 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute
specimens. Mark specimens plainly as "acute" or "convalescent."
Unacceptable Conditions: Contaminated or severely lipemic specimens.
CPT Code(s):
86606 Aspergillus Ab (CF); 86606 Aspergillus Ab (ID)
0050100
Aspergillus Antibody by CF
ASPER
Methodology:
Semi-Quantitative Complement Fixation
CPT Code(s):
86606
0050171
Aspergillus Antibody by ID
ASPER PPT
Methodology:
Qualitative Immunodiffusion
Specimen Preparation: Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum an ARUP Standard Transport
Unacceptable Conditions: Body fluid.
CPT Code(s):
86606
0097771
Aspergillus fumigatus Antibody, IgG by ELISA
ASPFUM IGG
Methodology:
Unacceptable Conditions: Contaminated, lipemic, or turbid specimens.
Stability: After separation form cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
CPT Code(s):
86606
2003150
Aspergillus Galactomannan Antigen by EIA, Bronchoscopy
ASPERAGB
Methodology:
Semi-quantitative Enzyme Immunoassay
Specimen Required: Collect: Lower respiratory material by bronchoscopy (BAL ,brushings, and washings).
Specimen Preparation: Transfer 2 mL bronchoscopy specimen to a sterile ARUP Standard Transport Tube (ARUP Supply #43115). Available
online through eSupply using ARUP Connect™ or contact Client Services at (800) 522-2787. (Min: 0.6 mL)
Unacceptable Conditions: Sputum. Specimens in media or preservatives. Grossly bloody specimens.
Stability: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 1 week
CPT Code(s):
87305
0060068
Aspergillus Galactomannan Antigen by EIA, Serum
ASPERAG
Methodology:
Specimen Preparation: Separate serum from cells within 2 hours of collection. Transfer 2 mL serum to a sterile ARUP Standard Transport Tube
(ARUP Supply #43115). Available online through eSupply using ARUP Connector contact Client Services at (800) 522-2787. (Min: 1 mL)
Unacceptable Conditions: Plasma. Serum separator tube. Hemolyzed specimens.
Stability: After separation from cells: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 1 week
CPT Code(s):
87305
0091570
Aspirin and Oxycodone Quantitation, Serum or Plasma
Methodology:
Quantitative Gas Chromatography-Mass Spectrometry/Spectrometry
Specimen Preparation: Transfer 3 mL serum or plasma to ARUP Standard Transport Tubes. (Min:1.5 mL)
CPT Code(s):
83925 Opiates; 80196 Salicylate
0091317
Methodology:
Page | 100
Atenolol, Serum or Plasma
High Performance Liquid Chromatography/Mass Spectrometry
PERCODAN S
ATENOLO
Stability: Ambient: 72 hours; Refrigerated: 2 weeks; Frozen: 2 weeks
CPT Code(s):
80299
0096047
Atenolol, Urine
Methodology:
Liquid Chromatography/Mass Spectrometry
Stability: Ambient: 72 hours; Refrigerated: 2 weeks; Frozen: 2 weeks
CPT Code(s):
80299
ATENOLO U
0091333
Atropine, Serum or Plasma
ATROPIN SP
Methodology:
(Min: 1.2)
CPT Code(s):
82542
0091171
Atropine, Urine
Methodology:
Stability: Ambient: 1 week; Refrigerated: 29 days; Frozen: 29 days
CPT Code(s):
82542
ATROPIN U
2007210
Autoimmune Liver Disease Evaluation with Reflex to Smooth Muscle Antibody (SMA), IgG by IFA
LIVER EVAL
Methodology:
Semi-Quantitative Enzyme-Linked Immunosorbent Assay/Semi-Quantitative Indirect Fluorescent Antibody
Tube. (Min: 0.6 mL)
Unacceptable Conditions: Non-serum specimens. Contaminated, heat-inactivated, grossly hemolyzed, grossly icteric, severely lipemic specimens
or inclusion of fibrin clot.
CPT Code(s):
83516 M2 IgG ; 86376 LKM-1 IgG; 83516 F-Actin IgG; if reflexed, add 86256 SMA, IgG titer.
0095505
Autoimmune Lymphoproliferative Profile
Methodology:
Quantitative Flow Cytometry
Specimen Required: Collect: Green (sodium or lithium heparin), lavender (EDTA), or pink (K2EDTA).
Specimen Preparation: Transport 5 mL whole blood. (Min: 0.5 mL)
Storage/Transport Temperature: CRITICAL ROOM TEMPERATURE.
Remarks: Specimens must be analyzed within 48 hours of collection.
Unacceptable Conditions: Frozen or refrigerated specimens. Specimens older than 48 hours. Clotted or hemolyzed specimens.
CPT Code(s):
86356 CD3; 86356 CD4; 86356 CD5; 86356 CD8; 86356 CD20; 86356 ALPHA/BETA; 86356 HLA-DR
ALPS
0092099
B-Cell CD20 Expression
CD20
Methodology:
Flow Cytometry
Specimen Required: Collect: Green (sodium heparin). Also acceptable: Lavender (EDTA) or pink (K2EDTA).
Specimen Preparation: Transport 5 mL whole blood.
Storage/Transport Temperature: Room temperature. Also acceptable: Refrigerated. Specimen should be received within 48 hours of collection for
optimal viable testing.
Remarks: Provide CBC, Wright's stained smear, clinical history, differential diagnosis, and any relevant pathology reports.
Unacceptable Conditions: Frozen specimens. Specimens greater than 48 hours old. Clotted or hemolyzed specimens.
CPT Code(s):
88184 First marker and 88185 Each additional marker; AND 88187 interpretation for 2-8 markers
Page | 101
0095940
B-Cell Immunodeficiency Profile
B-CELL
Methodology:
Quantitative Flow Cytometry
Specimen Required: Collect: Green (sodium or lithium heparin), lavender (EDTA), or pink (K2EDTA).
Remarks: Specimens must be analyzed within 48 hours of collection.
New York State Clients: Specimens in heparin must be analyzed within 48 hours of collection; specimens in EDTA must be analyzed within 30
hours of collection.
Unacceptable Conditions: Clotted, frozen, or refrigerated specimens. Specimens older than 48 hours.
New York State Clients: Clotted, frozen, or refrigerated specimens. Specimens in heparin that are more than 48 hours old and specimens in
EDTA that are more than 30 hours old.
New York State Clients: Ambient: 48 hours in heparin, 30 hours in EDTA; Refrigerated: Unacceptable; Frozen: Unacceptable.
CPT Code(s):
86356 CD19; 86356 PSIG; 86356 IGA; 86356 IGD; 86356 IGG; 86356 IGM; 86356 HLA-DR
2003442
B Cell Specific Octamer Binding Protein-1 (BOB-1) by Immunohistochemistry
BOB1 IHC
Methodology:
CPT Code(s):
88342
0030191
B-Type Natriuretic Peptide
BNP
Methodology:
Specimen Preparation: Separate plasma from cells within 2 hours of collection. Transfer 2 mL plasma to an ARUP Standard Transport Tube and
freeze within 4 hours of collection. (Min: 0.5 mL)
Unacceptable Conditions: Frozen whole blood. Specimens collected in non-EDTA tubes. Specimens frozen in separator tube. Specimen exposed
to repeated freeze/thaw cycles. Refrigerated or room temperature specimens more than 4 hours old. Hemolyzed specimens.
CPT Code(s):
83880
0093048
Babesia microti Antibodies, IgG & IgM by IFA
BAB MIC AB
Methodology:
Specimen Preparation: Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard
Transport Tube. (Min: 0.1 mL) Parallel testing is preferred, and convalescent specimens must be received within 30 days from receipt of the acute
Unacceptable Conditions: Bacterially contaminated, hemolyzed or lipemic specimens.
CPT Code(s):
86753 IgG; 86753 IgM
0093049
Babesia microti Antibody, IgG by IFA
BAB IGG
Methodology:
specimens. Mark specimens plainly as acute or convalescent.
Unacceptable Conditions: Bacterially contaminated, hemolyzed, or lipemic specimens.
CPT Code(s):
86753
0093050
Babesia microti Antibody, IgM by IFA
BAB IGM
Methodology:
Unacceptable Conditions: Bacterially contaminated, hemolyzed, or lipemic specimens.
CPT Code(s):
86753
2005275
Baclofen Quantitation, Fluid
Methodology:
Specimen Required: Collect: Fluid.
Page | 102
BACLO FL
CPT Code(s):
Specimen Preparation: Transfer 1 mL fluid to an ARUP Standard Transport Tube. (Min: 0.4 mL)
80299
2005273
Baclofen Quantitation, Serum or Plasma
BACLO SP
Methodology:
CPT Code(s):
80299
0060182
Bacterial Strain Characterization by Pulsed-Field Gel Electrophoresis
MC PFGE
Methodology:
Pulsed-Field Gel Electrophoresis
Specimen Required: Collect: Multiple bacterial isolates that are epidemiologically related or are recurrent isolates from the same patient.
Specimen Preparation: Transport individual isolates on agar slants or on swabs in bacterial transport media. Package isolates together in a sealed
container.
Remarks: Contact the Microbiology Laboratory at (800) 242-2787, extension 2248, prior to submission of the isolates. One report will be
generated for each batch tested; billing is per isolate. Order one test, using Infection control, #### (your ARUP client number) as the patient name.
Include a list of isolate identifiers (do not use patient names) on the requisition or as an order note for electronic orders. Identifiers on the
requisition must match identifiers on the isolate samples. Print the following instructions and include in the package:
Stability: Isolate: Ambient: 1 week; Refrigerated: Unacceptable; Frozen: Unacceptable.
CPT Code(s):
87152
0091093
Barbital, Serum or Plasma
Methodology:
Gas Chromatography
CPT Code(s):
82205
0091377
Barbital, Urine
Methodology:
Gas Chromatography
Specimen Required: Collect: Random urine
Storage/Transport Temperature: Room temperature
CPT Code(s):
82205
0091282
Barium, Serum or Plasma
Methodology:
Specimen Required: Collect: Royal blue (no additive or EDTA)
Specimen Preparation: Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) Also acceptable: Plasma
Unacceptable Conditions: Separator tubes
CPT Code(s):
83018
0091165
Barium, Urine
Methodology:
Specimen Required: Collect: Random urine in trace metal-free or acid-washed urine bottle.
CPT Code(s):
83018
BARBIT SP
BARBIT URN
BARIUM SP
BARIUM URN
2002280
Bartonella henselae & B. quintana Antibodies, IgG & IgM
BARTONELLA
Methodology:
CPT Code(s):
86611 Bartonella henselae IgG; 86611 Bartonella henselae IgM; 86611 Bartonella quintana IgG; 86611 Bartonella quintana IgM
0050091
Bartonella henselae Antibody, IgG by IFA
Methodology:
Page | 103
HENS G
CPT Code(s):
86611
0050092
Bartonella henselae Antibody, IgM by IFA
HENS M
Methodology:
CPT Code(s):
86611
0050108
Bartonella henselae (Cat Scratch) Antibodies, IgG & IgM by IFA
CATSCRATCH
Methodology:
CPT Code(s):
86611 Bartonella henselae IgG; 86611 Bartonella henselae IgM
0050106
Bartonella quintana Antibodies, IgG & IgM by IFA
BART PAN
Methodology:
CPT Code(s):
86611 Bartonella quintana Ab, IgG; 86611 Bartonella quintana Ab, IgM
0050094
Bartonella quintana Antibody, IgG by IFA
QUINT G
Methodology:
CPT Code(s):
86611
0050093
Bartonella quintana Antibody, IgM by IFA
QUINT M
Methodology:
CPT Code(s):
86611
0093057
Bartonella Species by PCR
BART DNA
Methodology:
Specimen Required: Collect: Lavender (EDTA), pink (K2EDTA) or serum separator tube. Also acceptable: CSF or tissue.
Specimen Preparation: Separate serum or plasma from cells. Transfer 1 mL serum, plasma or CSF to a sterile container. (Min: 0.5 mL). OR
Tissue: Transfer to a sterile container and freeze immediately.
Unacceptable Conditions: Whole blood (refer to Bartonella Species by PCR, Whole Blood, ARUP test code 0060762). Heparinized specimens.
Stability: Tissue: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 1 month. All Others: Ambient: 24 hours; Refrigerated: 5 days;
Frozen: 1 month.
CPT Code(s):
87471
0060762
Bartonella Species by PCR, Whole Blood
Methodology:
Page | 104
BARTPCR WB
CPT Code(s):
Specimen Preparation: : Do not freeze specimen. Transport 1 mL whole blood. (Min: 0.5 mL).
Unacceptable Conditions: Plasma (refer to Bartonella Species by PCR, ARUP test code 0093057). Frozen specimens. Heparinized specimens.
Stability: Ambient: 24 hours; Refrigerated: 5 days; Frozen: Unacceptable.
87471
0020399
Basic Metabolic Panel
BMP
Methodology:
Immunoturbidimetry/Polymerase Chain Reaction/Fluorescence Monitoring/Isoelectric Focusing
Specimen Required: Collect: Green (sodium or lithium heparin), plasma separator tube, or serum separator tube.
Specimen Preparation: Allow serum tube to clot completely at room temperature. Separate serum or plasma from cells within 30 minutes of
Unacceptable Conditions: Specimens collected in EDTA, citrate, or oxalate.
Stability: After separation from cells: Ambient: Calcium and CO2: 4 hours, All others: 24 hours; Refrigerated: 1 week; Frozen: 6 months
CPT Code(s):
80048
0055592
B-Cell Clonality Assessment by Restriction Fragment Southern Blot Hybridization
BCRFSBHF
Methodology:
Restriction Fragment Southern Blot Hybridization
Specimen Required: Collect: Lavender (EDTA) OR bone marrow (EDTA) OR fresh tissue..
Specimen Preparation: Whole blood: Transport 10 mL (Min: 3 mL) OR Bone marrow: Transport 3 mL (Min: 3 mL) OR Fresh tissue: Freeze
immediately. Transport 100 mg or 0.5-2.0 cm3 tissue. Transport frozen tissue in a tissue transport kit (ARUP supply #47808) available online
through eSupply using ARUP Connect™or contact ARUP Client Services at (800) 522-2787.
Storage/Transport Temperature: Whole blood OR Bone marrow: Refrigerated. OR Fresh tissue: Frozen on dry ice.
Unacceptable Conditions: Serum. Frozen whole blood or bone marrow. Clotted or grossly hemolyzed specimens. Paraffin-embedded tissue.
Stability: Whole blood OR Bone marrow: Ambient: 24 hours; Refrigerated: 5 days; Frozen: Unacceptable
Fresh tissue: Ambient: Unacceptable; Refrigerated: 2 hours; Frozen: 1 year
CPT Code(s):
83891 Isolation; 83892 x4 Enzymatic digestion; 83894 Gel separation; 83897 Southern transfer; 83896 Nucleic acid probe; 83912 Interpretation
2006193
B-Cell Clonality Screening (IgH and IgK) by PCR
BCELL SCRN
Methodology:
Polymerase Chain Reaction/Capillary Electrophoresis
Specimen Required: Collect: Lavender (EDTA) OR bone marrow (EDTA) OR tissue.
Storage/Transport Temperature: Whole blood OR Bone marrow: Refrigerated. Fresh tissue: Frozen on dry ice. FFPE tumor tissue: Room
temperature or refrigerated. Ship in cooled container during summer months.
Unacceptable Conditions: Whole blood OR Bone marrow: Frozen specimens. Clotted or grossly hemolyzed specimens. FFPE tumor tissue:
Specimens fixed/processed in alternative fixatives or heavy metal fixatives (B-4 or B-5) or tissue sections on slides. Decalcified specimens.
Fresh Tissue: Ambient: Unacceptable; Refrigerated: 2 hours; Frozen: 1 year
FFPE tumor tissue: Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable
CPT Code(s):
83891 Isolation; 83898 x6 Amplification; 83896 x5 Nucleic acid probes; 83909 x5 Capillary electrophoresis; 83912 Interpretation and report Additional CPT code modifiers may be required for procedures performed to test for oncologic or inherited disorders.
2006283
B-Cell Clonality Screening (IgH and IgK) by PCR with Reflex to B-Cell Clonality Assessment by Restriction
BCELL RFLX
Fragment Southern Blot Hybridization
Methodology:
Polymerase Chain Reaction/Capillary Electrophoresis/Restriction Fragment Southern Blot Hybridization
Specimen Required: Collect: Lavender (EDTA) OR bone marrow (EDTA) OR fresh tissue.
Storage/Transport Temperature: Whole blood OR Bone marrow: Refrigerated. OR Fresh tissue: Frozen on dry ice.
Unacceptable Conditions: Serum. Frozen whole blood or bone marrow. Clotted or grossly hemolyzed specimens. Paraffin-embedded tissue.
Fresh Tissue: Ambient: Unacceptable; Refrigerated: 2 hours; Frozen: 1 year
CPT Code(s):
83891 Isolation; 83898 x6 Amplification; 83896 x5 Nucleic acid probes; 83909 x5 Capillary electrophoresis; 83912 Interpretation and report. If
reflexed, add 83892 x4 Enzymatic digestion; 83894 Gel separation; 83897 Southern transfer; 83896 Nucleic acid probe; 83912 Interpretation and
report - Additional CPT code modifiers may be required for procedures performed to test for oncologic or inherited disorders.
2004513
BCL-2 by Immunohistochemistry
BCL2 IHC
Methodology:
CPT Code(s):
88342
2003457
Methodology:
Page | 105
BCL-6 by Immunohistochemistry
BCL6 IHC
CPT Code(s):
88342
0055553
BCR-ABL, t(9;22) Translocation Qualitative by RT-PCR
BCR-ABL
Methodology:
Reverse Transcription Polymerase Chain Reaction
Specimen Required: Collect: Lavender (EDTA) or bone marrow (EDTA).
Specimen Preparation: Transport 5 mL whole blood or 3 mL bone marrow. (Min: 1 mL whole blood or 1 mL bone marrow) Specimens must be
received within 48 hours of collection due to lability of RNA.
Unacceptable Conditions: Serum or plasma. Specimens collected in anticoagulants other than EDTA. Severely hemolyzed specimens. Frozen or
clotted specimens.
Stability: Ambient: 1 hour; Refrigerated: 48 hours; Frozen: Unacceptable
CPT Code(s):
83891 Isolation; 83902 Reverse transcription; 83898 x6 Amplification; 83894 x3 Gel separation; 83912 Interpretation and report - Additional
0040138
BCR-ABL1 Kinase Domain Mutation Analysis
BCRABL MUT
Methodology:
Specimen Preparation: Transport 5 mL whole blood or 3 mL bone marrow. (Min: 1 mL whole blood or 1 mL bone marrow)
Unacceptable Conditions: Serum or plasma. Frozen or clotted specimens. Specimens collected in anticoagulants other than EDTA. Severely
hemolyzed specimens.
CPT Code(s):
83891 Isolation; 83902 Reverse transcription; 83898 x4 Amplification; 83894 Gel detection; 83912 Interpretation and report. If sequencing is
performed, add: 83892 Enzyme digestion; 83904 Sequencing and 83909 Capillary electrophoresis. Additional CPT code modifiers may be
2005017
BCR-ABL1, Major (p210), Quantitative
BCR MAJ
Methodology:
Quantitative Reverse Transcription Polymerase Chain Reaction
clotted specimens.
CPT Code(s):
83891 Isolation; 83902 Reverse transcription; 83898 x2 Amplification; 83896 x2 Nucleic acid probes; 83912 Interpretation and report Additional CPT code modifiers may be required for procedures performed to test for oncologic or inherited disorders.
2005016
BCR-ABL1, Minor (p190), Quantitative
BCR MIN
Methodology:
Quantitative Reverse Transcription Polymerase Chain Reaction
clotted specimens.
CPT Code(s):
83891 Isolation; 83902 Reverse transcription; 83898 x2 Amplification; 83896 x2 Nucleic acid probes; 83912 Interpretation and report Additional CPT code modifiers may be required for procedures performed to test for oncologic or inherited disorders.
2005010
BCR-ABL1, Qualitative with Reflex to BCR-ABL1 Quantitative
BCR RFLX
Methodology:
clotted specimens.
CPT Code(s):
83891 Isolation; 83902 Reverse transcription; 83898 x6 Amplification; 83894 x3 Gel separation; 83912 Interpretation and report. If reflexed add
83902 Reverse transcription; 83898 x2 Amplification; 83896 x2 Nucleic acid probes; 83912 Interpretation and report - Additional CPT code
modifiers may be required for procedures performed to test for oncologic or inherited disorders.
2004924
BCR-ABL1, T315I Mutation Detection, Quantitative
Methodology:
Reverse Transcription Polymerase Chain Reaction/Pyrosequencing
Page | 106
ABL T315I
CPT Code(s):
Unacceptable Conditions: Serum or plasma. Specimens collected in anticoagulants other than EDTA. Frozen specimens. Clotted or severely
83891 Isolation; 83902 Reverse transcription; 83898 x2 Amplification; 83904 Sequencing; 83912 Interpretation and report - Additional CPT code
0091315
Belladonna Alkaloids Panel
BELLADONNA
Methodology:
CPT Code(s):
82542 x2 Atropine, scopolamine
2002464
Bence Jones Protein Detection, Quantitation and Characterization with Reflex to Quantitative Free Kappa
BJP-U REFLEX
and Lambda Light Chains, Urine
Methodology:
Semi-Quantitative Electrophoresis/Qualitative Immunofixation Electrophoresis/Quantitative Nephelometry
Specimen Required: Collect: 24-hour urine. Refrigerate during collection. Also acceptable: Urine supernatant.
Specimen Preparation: Transfer two 4 mL aliquots from well-mixed 24 hour collection to individual ARUP Standard Transport Tubes. (Min: 3
mL) Record total volume and collection time interval on transport tube and test request form.
Unacceptable Conditions: Non-refrigerated specimens.
CPT Code(s):
84156 Total protein; 84166 Protein fractionation; 86335 IFE; if reflexed, add 83883 x2 Nephelometry, kappa/lambda
0050161
Bence Jones Protein, Qualitative Free Kappa & Lambda Light Chains, Urine
BJQUAL
Methodology:
Qualitative Immunofixation Electrophoresis/Quantitative Nephelometry
Specimen Required: Collect: 24-hour urine. Refrigerate during collection. Also acceptable: Random specimens and urine supernate.
Specimen Preparation: Transfer two 4 mL aliquots from a well-mixed 24-hour urine collection to individual ARUP Standard Transport Tubes.
(Min: 4 mL) Record total volume and collection time interval on transport tube and test request form.
CPT Code(s):
84156 Total protein; 86335 IFE
0050618
Bence Jones Protein, Quantitative Free Kappa and Lambda Light Chains, Urine
BJ QUANT
Methodology:
Qualitative Immunofixation Electrophoresis/Quantitative Nephelometry
Specimen Required: Collect: 24-hour urine. Refrigerate during collection. Also acceptable: Random urine specimens and urine supernate.
Specimen Preparation: Transfer two 4 mL aliquots from a well-mixed 24-hour collection to individual ARUP Standard Transport Tubes. (Min: 3
mL) Record total volume and collection time interval on transport tube and test request form.
CPT Code(s):
84156 Total protein; 86335 IFE; 83883 x2 Nephelometry, kappa/lambda
0050689
Bence Jones Protein, Quantitative Free Kappa Light Chains, Urine
BJQNTKAPP
Methodology:
Quantitative Nephelometry/Qualitative Immunofixation Electrophoresis
Specimen Required: Collect: 24-hour urine. Refrigerate during collection. Also acceptable: Urine supernate.
Unacceptable Conditions: Random specimens. Non-refrigerated specimens.
CPT Code(s):
84156 Total protein; 86335 IFE; 83883 Nephelometry, kappa
0050682
Bence Jones Protein, Quantitative Free Lambda Light Chains, Urine
BJQNTLAMB
Methodology:
Quantitative Nephelometry/Qualitative Immunofixation Electrophoresis
Specimen Required: Collect: 24-hour urine. Refrigerate during collection. Also acceptable: Urine supernate.
Unacceptable Conditions: Random specimens. Non-refrigerated specimens.
CPT Code(s):
84156 Total protein; 86335 IFE; 83883 Nephelometry, lambda
0091209
Bendiocarb, Serum or Plasma
BENDIOC SP
Methodology:
High Performance Thin Layer Chromatography
CPT Code(s):
82491
Page | 107
0091201
Benzene Quantitation, Whole Blood
Methodology:
Specimen Required: Collect: Gray (potassium oxalate/sodium fluoride) or lavender (EDTA).
Stability: Ambient: Unacceptable; Refrigerated: 2 weeks; Frozen: 3 weeks
CPT Code(s):
84600
BENZ BLD
0090367
Benzodiazepines Detection
S BNZ
Methodology:
Fluorescence Polarization Immunoassay
Unacceptable Conditions: Specimens collected in separator tubes or fluoride. Specimens exposed to repeated freeze/thaw cycles.
CPT Code(s):
80101
0091516
Benztropine, Serum or Plasma
Methodology:
Gas Chromatography
Specimen Preparation: Transfer 5 mL serum or plasma to ARUP Standard Transport Tubes. (Min: 2.2 mL)
CPT Code(s):
80299
0091098
Benztropine, Urine
Methodology:
Gas Chromatography
CPT Code(s):
80299
BENZTROP S
BENZTR U
0091278
Beryllium, Serum or Plasma
BERYLLIUM
Methodology:
Specimen Required: Collect: Plain red or Royal blue (trace metal-free).
Specimen Preparation: Transfer 2 mL serum or plasma to an ARUP Trace Element-Free Transport Tube (ARUP supply #43116). (Min: 0.5 mL)
Unacceptable Conditions: Serum separator tubes.
Stability: Ambient: 72 Hours; Refrigerated: 2 weeks; Frozen: Indefinite
CPT Code(s):
83018
0091154
Methodology:
Beryllium, Urine
BERYLL URN
Quantitative Inductively Coupled Plasma-Mass Spectrometry/Colorimetry
High concentrations of gadolinium are known to interfere with most metals tests. If gadolinium-containing contrast media
has been administered, a specimen cannot be collected for 48 hours.
Specimen Required: Collect: Urine in a trace metal-free or acid-washed plastic container.
Specimen Preparation: Transfer 3 mL urine to an ARUP Trace Element-Free Transport Tube (ARUP supply #43116). Available online through
eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 1.8 mL)
Stability: Ambient: 1 week; Refrigerated: 1 week; Frozen: 2 weeks
CPT Code(s):
82570 Creatinine; 83018 Beryllium heavy metal, quantitative
0051288
Beta-2-Adrenergic Receptor (ADBR2) Haplotyping
ADRB2 HAP
Methodology:
CPT Code(s):
83891 Isolation; 83898 Amplification; 83896 x2 Nucleic acid probe; 83912 Interpretation and report - Additional CPT code modifiers may be
0050321
Beta-2 Glycoprotein 1 Antibodies, IgG & IgM
B2GPI PAN
Methodology:
Tube. (Min: 0.3 mL)
Unacceptable Conditions: Plasma or other body fluids. Contaminated, hemolyzed, grossly icteric, or severely lipemic specimens.
CPT Code(s):
86146 Beta-2 Glycoprotein I, IgG; 86146 Beta-2 Glycoprotein I, IgM
2002569
Methodology:
Page | 108
Beta-2 Glycoprotein 1 Antibodies, IgG, IgM & IgA
B2GPI PAN3
CPT Code(s):
86146 Beta-2 Glycoprotein I, IgG; 86146 Beta-2 Glycoprotein I, IgM; 86146 Beta-2 Glycoprotein I, IgA
0050324
Beta-2 Glycoprotein 1 Antibody, IgA
B2GPI A
Methodology:
Tube. (Min: 0.3 mL)
CPT Code(s):
86146
0080054
Beta-2 Microglobulin, CSF
B2M CSF
Methodology:
Specimen Required: Collect: CSF. Also acceptable: CSF collected in plain red or green (sodium or lithium heparin).
Specimen Preparation: Centrifuge to remove cellular material. Transfer 0.5 mL CSF to an ARUP Standard Transport Tube. (Min: 0.4 mL)
Stability: After separation from cellular material: Ambient: 8 hours; Refrigerated: 1 week; Frozen: 2 weeks
CPT Code(s):
82232
0080053
Beta-2 Microglobulin, Serum or Plasma
B2M S
Methodology:
Specimen Required: Collect: Serum separator tube. Also acceptable: Green (sodium or lithium heparin), lavender (EDTA), or pink (K2EDTA).
Unacceptable Conditions: CSF (refer to Beta-2 Microglobulin, CSF, ARUP test code 0080054)
CPT Code(s):
82232
0080432
Methodology:
Beta-2 Microglobulin, Urine
B2M U
Void the urinary bladder, then drink a large glass of water and collect a urine specimen within 1 hour.
Specimen Preparation: Transfer one 3 mL aliquot from a well-mixed random collection to an ARUP Standard Transport Tube. (Min: 1 mL)
If pH is greater than 8, lower pH to 6-8 by adding 1M HCL. If pH less than 6, increase pH to 6-8 by adding 5% NaOH. Titrate with appropriate
preservative until pH of 6-8 has been reached. Record the pH on the transport tube and test request form.
Stability: Ambient: 8 hours; Refrigerated: 48 hours; Frozen: 2 months
CPT Code(s):
82232
0050047
Beta-2 Transferrin
B2TRNSF
Methodology:
Qualitative Immunofixation Electrophoresis
Specimen Required: Collect: Serum separator tube (SST) or plain red AND aural or nasal fluid in sterile container.
Specimen Preparation: Do not freeze. Separate serum from cells ASAP or within 2 hours of collection. Transport 2 mL serum AND 2 mL aural or
nasal fluid in a tube without preservative. (Min: 0.5 mL serum and 1 mL aural or nasal fluid)
CPT Code(s):
86334 IFE Serum; 86335 IFE Fluid
2003454
Beta-Catenin-1 by Immunohistochemistry
BCAT1 IHC
Methodology:
CPT Code(s):
88342
2002434
(1,3)-Beta-D-Glucan (Fungitell®)
BDGLUCAN
Methodology:
Semi-Quantitative Colorimetry
Specimen Preparation: Separate serum from cells within 2 hours of collection. Transfer 2 mL serum to a sterile ARUP Standard Transport Tube
(ARUP supply # 43115). Available online through eSupply using ARUP Connector contact ARUP Client Services at (800) 522-2787. (Min: 0.5
mL)
Page | 109
CPT Code(s):
Stability: Ambient: Unacceptable, Refrigerated: 2 weeks; Frozen: 2 weeks
87449
0050578
Beta Globin (HBB) Gene Sequencing
BGSEQ
Methodology:
Specimen Required: Collect: Lavender (EDTA) or pink (K2EDTA). Also acceptable: Yellow (ACD Solution A or B).
CPT Code(s):
83891 Isolation; 83898 x4 Amplification; 83894 Gel electrophoresis; 83904 x3 Sequencing; 83909 Capillary electrophoresis; 83912 Interpretation
0051421
Beta Globin (HBB) HbS, HbC, & HbE Mutations
HB SCE
Methodology:
CPT Code(s):
83891 Isolation; 83898 x2 Amplification; 83896 x3 Nucleic acid probe; 83912 Interpretation and report - Additional CPT code modifiers may be
0051422
Beta Globin (HBB) HbS, HbC, and HbE Mutations, Fetal
HB SCE FE
Methodology:
CPT Code(s):
83891 Isolation; 83898 x2 Amplification; 83896 x3 Nucleic acid probes; 83912 Interpretation and report. FCC: 83900 Multiplex amplification
(first two sequences); 83901 x14 Additional amplification; 83909 Capillary electrophoresis. If MCC Maternal Cell (0050608) is performed, add:
83891 Isolation; 83900 Multiplex amplification; 83901 x14 Additional amplification; 83909 Capillary electrophoresis; 83912 Interpretation and
0050388
Beta Globin (HBB) Sequencing, Fetal
BGSEQ FE
Methodology:
Specimen Required: Collect: Fetal Specimen: Two T-25 flasks at 80% confluent of cultured amniocytes. If the client is unable to culture amniocytes, this can be
OR Whole Blood in lavender (EDTA), pink (K2EDTA), or yellow (ACD Solution A or B).
Specimen Preparation: Cultured Amniocytes: Fill flasks with culture media. Transport two T-25 flasks at 80% confluent of cultured amniocytes
filled with culture media. Backup cultures must be retained at the client's institution until testing is complete.
AND Maternal Cell Contamination Specimen: Transport 3 mL whole blood (Min: 1 mL)
CPT Code(s):
OR Whole Blood: Transport 3 mL whole blood (Min: 1 mL)
Whole Blood or Maternal Cell Contamination Specimen: Room temperature.
Whole Blood or Maternal Cell contamination Specimen: Ambient: 72 hours; Refrigerated: 1 week; Frozen: Unacceptable
83891 Isolation; 83898 x4 Amplification; 83894 Gel separation; 83904 x3 Sequencing; 83909 Capillary electrophoresis; 83912 Interpretation and
report. FCC: 83900 Multiplex amplification; 83901 x14 Additional Amplification; 83909 Capillary electrophoresis. For MCC Maternal cell
(0050608) add: 83891 Isolation; 83900 Multiplex amplification; 83901 x14 Additional amplification; 83909 Capillary electrophoresis; 83912
0070029
Beta-hCG, Quantitative (Tumor Marker)
BHCG TM
Methodology:
Quantitative Electrochemiluminescent Immunoassay
Specimen Required: Collect: Serum separator tube. Also acceptable: Lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin).
Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.4 mL)
Unacceptable Conditions: CSF (refer to Beta-hCG, Quantitative (Tumor Marker) CSF, ARUP test code 0020730). Specimens left to clot at 2-8°C
or specimens subjected to repeated freeze/thaw cycles.
Page | 110
CPT Code(s):
84702
0020730
Beta-hCG, Quantitative (Tumor Marker), CSF
Methodology:
Specimen Required: Collect: CSF. Also acceptable: CSF collected in plain red or green (sodium or lithium heparin).
Specimen Preparation: Transfer 0.5 mL CSF to an ARUP Standard Transport Tube. (Min: 0.3 mL)
Unacceptable Conditions: Any other body fluids.
CPT Code(s):
84702
BHCG CSF
0020063
Beta-hCG, Serum Qualitative
Methodology:
Immunoassay
Unacceptable Conditions: Plasma. Specimens exposed to repeated freeze/thaw cycles.
CPT Code(s):
84703
BHCG-S
0070025
Beta-hCG, Serum Quantitative
BHCG QNT
Methodology:
Chemiluminescent Immunoassay
Specimen Required: Collect: Plasma separator tube (PST), serum separator tube (SST), or plain red.
Specimen Preparation: Serum specimens must sit for 15-20 minutes for proper clot formation and to assure the absence of fibrin in the serum,
which can interfere with this test. Separate serum from cells within 24 hours of collection. Transfer 2 mL serum to an ARUP Standard Transport
Tube. (Min: 0.5 mL)
Remarks: This test is not appropriate for tumor marker studies and should not be performed on males.
Unacceptable Conditions: Specimens exposed to repeated freeze/thaw cycles. Test ordered for tumor markers or on males.
Stability: After separation from cells: Ambient: 8 hours; Refrigerated: 1 week; Frozen: 1 year
CPT Code(s):
84702
0020229
Beta-hCG, Urine Qualitative
BHCG-U
Methodology:
Immunoassay
Specimen Required: Collect: Urine in a plastic container. First-morning urine is the preferred specimen as it usually contains the highest concentration of beta-hCG;
however, any specimen is suitable for testing.
Specimen Preparation: Transfer 1 mL aliquot of urine to an ARUP Standard Transport Tube. If frozen, mix after thawing. Do not refreeze.
Stability: Ambient: 8 hours; Refrigerated: 72 hours; Frozen: 6 months (one freeze/thaw cycle is acceptable)
CPT Code(s):
81025
0080045
Beta-Hydroxybutyric Acid
B-OH
Methodology:
Specimen Required: Collect: Serum separator tube, lavender (EDTA), pink (K2EDTA), green (sodium or lithium heparin), or gray (sodium fluoride/potassium oxalate).
CPT Code(s):
82010
2003466
BF-1 by Immunohistochemistry
BF1 IHC
Methodology:
CPT Code(s):
88342
BICARB
0020245
Bicarbonate (HCO3), Urine
Methodology:
Enzymatic
Specimen Required: Collect: Random urine in sealed container.
Specimen Preparation: Immediately upon collection, mix and transfer 4 mL urine to an ARUP Standard Transport Tube. (Min: 0.3 mL) Do not
expose to air.
Unacceptable Conditions: Room temperature or refrigerated specimens.
Stability: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 1 month (unstable if thawed and refrozen)
CPT Code(s):
82374
0092610
Methodology:
Page | 111
Bile Acids, Fractionated and Total by LC-MS/MS
BILE ACIDS
Patient should fast for a minimum of eight hours prior to specimen collection.
Specimen Preparation: After clot formation, centrifuge specimen and pour off serum into a transport tube. Transfer 1 mL serum to an ARUP
Storage/Transport Temperature: Refrigerated. Store specimen refrigerated or frozen.
Stability: Ambient: 8 hours; Refrigerated: 2 weeks; Frozen: 6 months
CPT Code(s):
83789
0070189
Methodology:
Bile Acids, Total
BILE AC
Patient should fast for 8 hours prior to collection.
Specimen Preparation: Allow specimen to clot completely at room temperature before centrifugation. Transfer 1 mL serum to an ARUP Standard
Unacceptable Conditions: Body fluids. Heparinized specimens. Hemolyzed specimens.
Stability: After separation from cells: Ambient: 8 hours; Refrigerated: 2 weeks; Frozen: 6 months
CPT Code(s):
82239
2005248
Bilirubin, CSF
BILCSF
Methodology:
Specimen Required: Collect: CSF. Collect at least 12 hours after suspected hemorrhage. Use the last (ideally the fourth) specimen post lumbar puncture. AND serum
separator tube.
Specimen Preparation: CSF: Transport to local lab quickly and avoid pneumatic tube transport if possible. Protect from light during collection,
storage and shipment. Centrifuge for 5 minutes ASAP or within 1 hour of collection. Transfer 2 mL CSF to an ARUP Amber Transport Tube.
(Min: 1 mL) Do not freeze.
Serum: Protect from light during collection, storage and shipment. Allow specimen to clot completely at room temperature. Separate from cells
ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Amber Transport Tube. (Min: 0.5 mL)
Unacceptable Conditions: Specimens not protected from light. Frozen CSF.
Stability: CSF: Ambient: 4 hours; Refrigerated: 1 week; Frozen: Unacceptable
Serum: Ambient: 4 hours; Refrigerated: 1 week; Frozen: 6 months
CPT Code(s):
84311 Net absorbance, Bilirubin, CSF; 84311 Net absorbance, Oxyhemoglobin, CSF; 82247 Total serum bilirubin
0020426
Bilirubin, Direct & Total, Serum or Plasma
BILI
Methodology:
Specimen Preparation: Protect from light during collection, storage, and shipment. Allow serum tube to clot completely at room temperature.
Separate serum or plasma from cells within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Amber Transport Tube. (Min: 0.2
mL)
Stability: After separation from cells if protected from light: Ambient: 4 hours; Refrigerated: 1 week; Frozen: 6 months
CPT Code(s):
82247 Total bilirubin; 82248 Direct bilirubin
0020033
Bilirubin, Direct, Serum or Plasma
BILID
Methodology:
Specimen Preparation: Protect from light during collection, shipment and storage. Allow serum tube to clot completely at room temperature.
mL)
CPT Code(s):
82248
0020510
Bilirubin, Total, Body Fluid
TBILI-FL
Methodology:
Specimen Preparation: Protect from light during collection, storage, and shipment. Transfer 0.5 mL body fluid to an ARUP Amber Transport
Tube. (Min: 0.2 mL)
Unacceptable Conditions: Amniotic fluid, (refer to Amniotic Bilirubin Scan, ARUP test code 0080276) or CSF (refer to Bilirubin, CSF, ARUP
test code 2005248). Breast milk and salivary fluid. Specimens too viscous to be aspirated by instrument.
Stability: If protected from light: Ambient: 4 hours; Refrigerated: 1 week; Frozen: 6 months
CPT Code(s):
82247
0020032
Bilirubin, Total, Serum or Plasma
BILIT
Methodology:
Spectrophotometry
Specimen Required: Collect: Plasma separator tube or serum separator tube. Also acceptable: Lavender (EDTA), pink (K2EDTA) or green (sodium or lithium heparin).
Specimen Preparation: Protect from light during collection, storage and shipment. Allow serum tube to clot completely at room temperature.
mL)
CPT Code(s):
82247
Page | 112
0051700
Biotinidase Deficiency (BTD) 5 Mutations
BTD MUT
Methodology:
Polymerase Chain Reaction/Capillary Electrophoresis
Specimen Required: Collect: Lavender (EDTA), pink (K2EDTA), or yellow (ACD solution A or B).
CPT Code(s):
83891 Isolation; 83900 Multiplex amplification; 83901 x2 Additional amplification; 83914 x5 Extension; 83909 Capillary electrophoresis; 83912
Interpretation and report - Additional CPT code modifiers may be required for procedures performed to test for oncologic or inherited disorders.
0051730
Biotinidase Deficiency (BTD) Sequencing
Methodology:
CPT Code(s):
83891 Isolation; 83898 x6 Amplification; 83904 x6 Sequencing; 83909 Capillary electrophoresis; 83912 Interpretation and report.
BTD FGS
0093362
Methodology:
Biotinidase, Serum (with Paired Normal Control)
BTD ENZ
Spectrophotometry
A control specimen needs to be sent with the patient specimen. The control specimen needs to be drawn from a normal,
healthy individual who is not biologically related to the patient. Collect control specimen within 30 minutes of patient specimen.
Specimen Required: Collect: Plain red or serum separator tube (patient) AND plain red serum separator tube (control).
Specimen Preparation: Separate serum from cells and freeze ASAP or within 2 hours of collection. Transfer 2 mL serum (patient) AND 2 mL
serum (control) to individual ARUP Standard Transport Tubes. (Min: 0.2 mL (patient) AND 0.2 mL (control)). Label control tube as "Control for
[patient name]".
Storage/Transport Temperature: CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered. Ship patient
and control specimens together.
Unacceptable Conditions: Refrigerated or room temperature specimens. Specimens subjected to more than one freeze/thaw cycle.
Stability: After separation from cells: Ambient: 1 hour; Refrigerated: 1 hour; Frozen: 1 month
CPT Code(s):
82261
0055691
BIRC2-MALT1 (API2-MALT1) Translocation, t(11;18) by RT-PCR
API2-MLT1
Methodology:
Specimen Required: Collect: Tissue.
Specimen Preparation: Freeze fresh tissue immediately. Transport 100 mg or 0.5 cm3 tissue.
OR Formalin fix (10% neutral buffered formalin) and paraffin embed tissue. Transport tissue block or 4 tissue scrolls (tissue shavings), 10
microns thick. Protect paraffin block from excessive heat.
Storage/Transport Temperature: Fresh tissue: Frozen at -70°C.
OR formalin-fixed, paraffin-embedded tissue: Room temperature or refrigerated. Ship in cooled container during summer months.
Unacceptable Conditions: Specimens fixed/processed in alternative fixatives (alcohol, Prefer®) or heavy metal fixatives (B-4 or B-5). Slides.
Decalcified tissue.
Stability: Fresh tissue: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen at -70°C: 48 hours
Formalin-fixed, paraffin-embedded tissue: Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable
CPT Code(s):
83891 Isolation; 83902 Reverse transcription; 83898 x3 Amplification; 83894 Gel separation; 83912 Interpretation and report - Additional CPT
0099478
Methodology:
Bismuth, Blood
BS B
CPT Code(s):
83018
0099410
Methodology:
Bismuth, Urine
BS U
CPT Code(s):
83018
0090067
BK Virus, Quantitative PCR
Methodology:
Specimen Required: Collect: Lavender (EDTA), pink (K2EDTA) or serum separator tube. OR Urine.
Page | 113
BK QNT
CPT Code(s):
Specimen Preparation: Do not freeze whole blood specimens. Transport 1 mL whole blood, serum, plasma or urine in a sterile container. (Min: 0.5
mL).
Unacceptable Conditions: Frozen whole blood. Heparinized specimens.
87799
2002304
BK Virus, Quantitative PCR, Blood
BK QNT BLD
Methodology:
Specimen Required: Collect: Lavender (EDTA), pink (K2EDTA), or serum separator tube
Specimen Preparation: Do not freeze whole blood specimens. Transport 1 mL whole blood, serum or plasma in a sterile container. (Min: 0.5 mL).
Unacceptable Conditions: Urine (refer to BK Virus, Quantitative PCR, Urine, ARUP test code 2002310). Frozen whole blood. Heparinized
specimens.
CPT Code(s):
87799
2002310
BK Virus, Quantitative PCR, Urine
BK QNT URN
Methodology:
Specimen Preparation: Transfer 1 mL urine to a sterile container. (Min: 0.5 mL).
Unacceptable Conditions: Plasma, serum or whole blood (refer to BK Virus, Quantitative PCR, Blood, ARUP test code 2002304).
Stability: Ambient: 24 hours; Refrigerated: 5 days; Frozen: 1 month.
CPT Code(s):
87799
8100500
Bladder Tumor Associated Antigen
Methodology:
Qualitative Immunoassay
Specimen Preparation: Transport 2 mL urine.
Unacceptable Conditions: Bladder washings, plasma, serum, or whole blood.
CPT Code(s):
86294
BT REPORT
0050626
Blastomyces Antibodies by CF & ID
BLASTO PAN
Methodology:
Semi-Quantitative Complement Fixation/Qualitative Immunodiffusion
CPT Code(s):
86612 Blastomyces Ab (CF); 86612 Blastomyces Ab (ID)
0050130
Blastomyces Antibody by CF
BLASTO
Methodology:
CPT Code(s):
86612
0050172
Blastomyces Antibody by ID
BLASTO PPT
Methodology:
Tube. (Min: 0.1 mL)
Unacceptable Conditions: Body fluids.
CPT Code(s):
86612
2002926
Blastomyces dermatitidis Antigen EIA
BLAST DERM
Methodology:
Specimen Required: Collect: Random urine. OR plain red, serum separator tube, or green (sodium or lithium heparin). Also acceptable: CSF or BAL.
Specimen Preparation: Transfer 2 mL urine, serum, or plasma to an ARUP Standard Transport Tube. (Min: 1 mL)
Stability: Ambient: 2 weeks; Refrigerated: 2 weeks; Frozen: Indefinitely
CPT Code(s):
87449-90
Page | 114
0062224
Blastomyces dermatitidis Identification by DNA Probe
MC BP
Methodology:
Nucleic Acid Probe
Specimen Required: Collect: Actively growing fungal isolate in pure culture
Specimen Preparation: Transport sealed container with pure culture on non-blood containing fungal medium. Place each specimen in individually
sealed bag.
Remarks: Results may be delayed if growth of the organism is inadequate.
Unacceptable Conditions: Mixed or non-viable organisms. Agar plate.
CPT Code(s):
87149
2003417
Bleeding Disorders (Common)
BLEED COM
Methodology:
Microlatex Particle-Mediated Immunoassay/Platelet Agglutination/Electromagnetic Mechanical Clot Detection
Remarks:
Stability: Ambient: 4 hours; Refrigerated: Unacceptable; Frozen at -20°C: 3 months; Frozen at -70°C: 6 months
CPT Code(s):
85240 F8; 85246 vWF/AG; 85245 vWF/RCF; 85250 Factor IX ; 85270 Factor XI; 85610 PT; 85730 PTT
2003947
Bleeding Disorders (Uncommon) with Reflex to Factor XIII 1:1 Mix and/or Fibrinogen Antigen
BLEED UCOM
Methodology:
Electromagnetic Mechanical Clot Detection/Solubility/Radial Immunodiffusion
Specimen Preparation: Transfer 8 mL platelet-poor plasma to ARUP Standard Transport Tubes. (Min: 6 mL)
Stability: Ambient: 4 hours; Refrigerated: Unacceptable; Frozen: 2 weeks
CPT Code(s):
85610 PT; 85730 PTT; 85210 Factor II; 85220 Factor V; 85230 Factor VII; 85260 Factor X; 85291 Factor XIII: if reflexed add factor 13 1:1 mix
85291; 85384 Fibrinogen; if reflexed add 85385 Fibrinogen Antigen
0060102
Methodology:
Blood Culture
MC BLD
Continuous Monitoring Blood Culture/Identification
Aseptic draw.
Specimen Required: Collect: Bactec® aerobic resin bottle and standard anaerobic bottle. For infants, use pediatric bottle.
Specimen Preparation: Transfer blood to a Bactec® aerobic resin bottle and standard anaerobic bottle using aseptic techniques, as defined for
blood culture collection. Site of specimen draw is required (e.g. left antecubital, A-line, etc).
Adult minimum: 3 mL blood (aerobic: 8-10 mL recommended, anaerobic: 5-7 mL recommended).
Pediatric minimum: 1 mL blood (1-3 mL recommended).
*Low volume will result in decreased recovery of pathogens.
Remarks: Note in the order if the patient is suspected of having Bartonella, Brucella, or any other unusual organism. Refer to Brucella Culture
(ARUP test code 0060159) or Legionella Species Culture (ARUP test code 0060113) for additional information.
Unacceptable Conditions: More than four blood culture sets per 24 hours.
CPT Code(s):
87040
0060060
Methodology:
Blood Culture, Acid-Fast Bacillus (AFB)
Aseptic draw.
Specimen Required: Collect: Whole blood in yellow (SPS) (ARUP supply #24964) or in Bactec® Myco/F Lytic bottle (ARUP supply # 31916).
OR bone marrow in yellow (SPS) (ARUP supply # 24964).
Specimen Preparation: Whole Blood: Transport 7 mL in tube or 5 mL bottle. (Min: 1 mL)
Bone Marrow: Transport 7 mL in tube. (Min: 0.5 mL)
Storage/Transport Temperature: Room Temperature
CPT Code(s):
87116
MC BAFB
0060024
Methodology:
Blood Culture, AFB and Fungal
BACTEC® Continuous Monitoring Blood Culture/Identification
Aseptic draw.
Bone Marrow: Transport 7 mL in tube. (Min: 0.5 mL)
CPT Code(s):
87103 Fungal culture, blood; 87116 AFB culture
MC BLDAF
0060070
Methodology:
MC BFUNG
Blood Culture, Fungal
Aseptic draw.
Page | 115
CPT Code(s):
OR Bone Marrow: Transport 7 mL in tube. (Min: 0.5 mL)
87103
2004741
Blood Group (5 Minor Antigens) Genotyping by Bead Array
BLD GROUP5
Methodology:
Polymerase Chain Reaction/Bead Array
Specimen Preparation: Transfer 7 mL whole blood to ARUP Standard Transport Tubes. (Min: 2 mL) Specimen must be labeled with patient's
name, date of birth, and the date and time of draw.
Stability: Ambient: 72 hours; Refrigerated: 2 weeks; Frozen: Unacceptable
CPT Code(s):
83891 Isolation; 83892 Digestion; 83900 Multiplex amplification; 83901 x16 Additional amplification; 83914 x25 Mutation identification; 83909
Separation and identification; 83912 Interpretation and report - Additional CPT code modifiers 4H (Kell) or 4Z (blood typing) may be required.
2004743
Blood Group (9 Minor Antigens) Genotyping by Bead Array
BLD GROUP9
Methodology:
Polymerase Chain Reaction/Bead Array
name, date of birth, and the date and time of draw.
CPT Code(s):
83891 Isolation; 83892 Digestion; 83900 x2 Multiplex amplification; 83901 x21 Additional amplification; 83914 x31 Mutation identification;
83909 Separation and identification; 83912 Interpretation and report - Additional CPT code modifiers 4H (Kell) or 4Z (blood typing) may be
required.
2004739
Blood Group (ABO & 8 Minor Antigens) Genotyping by Microarray
BLD GROUP8
Methodology:
Polymerase Chain Reaction/ASH Microarray
name, date of birth, and date and time of draw.
CPT Code(s):
83890 Isolation; 83892 Digestion; 83898 Amplification; 83900 x2 Multiplex amplification; 83901 x30 Additional amplification; 88386
Microarray, 250-500 probes; 83912 Interpretation and report
0051433
Bloom (BLM) 2281del6/ins7 Mutation
BLM
Methodology:
CPT Code(s):
83891 Isolation; 83892 x2 Enzymatic digestion; 83898 Amplification; 83914 Mutation identification; 83909 Separation and identification; 83912
0051434
Bloom (BLM) 2281del6/ins7 Mutation, Fetal
BLM FE
Methodology:
CPT Code(s):
83891 Isolation; 83892 x2 Digestion; 83898 Amplification; 83914 Extension; 83909 Capillary electrophoresis 83912 Interpretation and report.
FCC: 83900 Multiplex amplification (first two sequences); 83901 x14 Additional amplification; 83909 Capillaryelectrophoresis. If MCC MAT
(0050608) is performed: 83891 Isolation; 83900 Multiplex amplification; 83901 x14 Additional amplification; 83909 Capillary electrophoresis;
83912 Interpretation and report - Additional CPT code modifiers may be required for procedures performed to test for oncologic or inherited
disorders.
0060108
Body Fluid Culture and Gram Stain
MC BF
Methodology:
Specimen Required: Collect: Aspirate of amniotic, culdocentesis, pericardial, peritoneal, synovial, thoracentesis, or fluid.
OR body fluid collected in blood culture bottle(s), accompanied by original fluid (if possible).
Specimen Preparation: Transfer aspirate to a sterile tube, sterile container, or anaerobe gel transport tube. Place each specimen in an individual
sealed bag.
Page | 116
CPT Code(s):
Remarks: Specimen source required. Anaerobe Culture (ARUP test code 0060143) will be performed on properly collected and transported
specimens.
Unacceptable Conditions: Specimens submitted in anticoagulant other than SPS. Syringes with needle attached.
87070
0060103
Bone Culture
MC BONE
Methodology:
Culture/Identification
Specimen Required: Collect: Bone.
Specimen Preparation: Transfer bone to a sterile container and place on gauze moistened with sterile non-bacteriostatic saline to prevent drying.
Unacceptable Conditions: Dry specimens.
CPT Code(s):
87070
0060104
Bone Marrow Culture
MC BM
Methodology:
Specimen Required: Collect: Bone marrow, aspirate in sterile SPS Vacutainer® tube (ARUP Supply #24964). Available online through eSupply using ARUP
Connect™ or contact ARUP Client Services at (800) 522-2787.
Specimen Preparation: Transport bone marrow in SPS tube. (Min: 0.5 mL)
For AFB and fungal culture order Blood Culture, AFB & Fungal (ARUP test code 0060024).
Unacceptable Conditions: Specimens submitted in anticoagulant other than SPS.
CPT Code(s):
87070
Bone Marrow Services
Methodology:
Microscopy
Specimen Required: Collect: Contact your ARUP Business Development Manager or the Hematopathology Department at (800) 242-2787 for more information.
CPT Code(s):
Bone marrow in lavender (EDTA) or pink (K2EDTA).
Specimen Preparation: Transport 5 mL bone marrow (Min: 5 mL).
AND transport 2 unfixed bone marrow aspirate slides for each stain requested (Min: 2 slides/stain).
Remarks: Collection/Submission instructions must be followed. Submit clinical history and a preliminary report. If special studies are anticipated
such as cytogenetics, flow cytometry, etc., submit additional specimens in appropriate anticoagulant/fixative if required.
Unacceptable Conditions: Specimens older than 24 hours. Clotted or hemolyzed specimens.
Varies, depending upon actual testing performed.
0070053
Bone Specific Alkaline Phosphatase
Methodology:
Specimen Required: Collect: Serum separator tube. Also acceptable: Green (sodium or lithium heparin).
Unacceptable Conditions: Urine. Grossly hemolyzed specimens.
CPT Code(s):
84080
BSAP
2001774
Bordetella pertussis Antibodies, IgA and IgG by ELISA with Reflex to Immunoblot
BORDPAN2
Methodology:
Semi-Quantitative Enzyme-Linked Immunosorbent Assay/Qualitative Immunoblot
Tube. (Min: 0.3 mL) Parallel testing is preferred, and convalescent specimens must be received within 30 days from receipt of the acute
Unacceptable Conditions: Contaminated, heat-inactivated, or severely lipemic specimens.
CPT Code(s):
86615 x2 Bordetella IgA and IgG; if reflexed, add 86615 for each Bordetella Immunoblot
2001775
Bordetella pertussis Antibodies, IgA, IgG, and IgM by ELISA with Reflex to Immunoblot
BORDPAN3
Methodology:
Tube. (Min: 0.3 mL) Parallel testing is preferred, and convalescent specimens must be received within 30 days from receipt of the acute
CPT Code(s):
86615 x3 Bordetella (IgA, IgG, & IgM); if reflexed, add 86615 for each Bordetella Immunoblot
2004328
Bordetella pertussis Antibodies, IgA, IgG, & IgM by Immunoblot
Methodology:
Qualitative Immunoblot
Page | 117
BORD BLOTS
CPT Code(s):
Tube. (Min: 0.2 mL)
Unacceptable Conditions: Heat-inactivated specimens.
86615 x3
2001784
Bordetella pertussis Antibodies, IgG and IgM by ELISA with Reflex to Immunoblot
BORDPAN
Methodology:
Tube. (Min: 0.3 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens.
CPT Code(s):
86615 x2 Bordetella (IgG & IgM); if reflexed add 86615 for each Bordetella Immunoblot
2004316
Bordetella pertussis Antibody, IgA by Immunoblot
BORDA BLOT
Methodology:
Unacceptable Conditions: Contaminated or heat-inactivated specimens.
CPT Code(s):
86615
2005268
Bordetella pertussis Antibody, IgG by ELISA
BORDIGG
Methodology:
Unacceptable Conditions: Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimens.
CPT Code(s):
86615
2001768
Bordetella pertussis Antibody, IgG by ELISA with Reflex to Immunoblot
BORDG
Methodology:
CPT Code(s):
86615 Bordetella IgG; if reflexed add 86615 Bordetella IgG Immunoblot
2004327
Bordetella pertussis Antibody, IgG by Immunoblot
BORDG BLOT
Methodology:
CPT Code(s):
86615
2001769
Bordetella pertussis Antibody, IgM by ELISA with Reflex to Immunoblot
BORDM
Methodology:
Tube. (Min: 0.1 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens.
CPT Code(s):
86615 Bordetella IgM; if reflexed add 86615 for Bordetella IgM Immunoblot
2004326
Bordetella pertussis Antibody, IgM by Immunoblot
BORDM BLOT
Methodology:
Page | 118
CPT Code(s):
86615
0065078
Bordetella pertussis by PCR
BPERT
Methodology:
Polymerase Chain Reaction
Specimen Required: Collect: Respiratory specimens on rayon or Dacron® swab, or direct respiratory specimen such as BAL, respiratory aspirate, or sputum.
Specimen source is required.
Storage/Transport Temperature: 2 mL respiratory specimen on swab or direct respiratory specimen should be sent in sterile container, or in viral
transport media (Microtest M4 or UTM) (ARUP supply #12884), frozen. (Min: 0.5 mL)
Unacceptable Conditions: Calcium-alginate swabs (shown to inhibit PCR). Respiratory aspirates in collection containers with tubing.
Stability: Ambient: 4 hours; Refrigerated: 2 days; Frozen: 2 weeks
CPT Code(s):
87798
0060117
Bordetella pertussis Culture
MC PERT
Methodology:
Specimen Required: Collect: Nasal aspirate or washing or nasopharyngeal swab.
Specimen Preparation: Aspirate or Washing: Transfer to a sterile container.(Min: 0.5 mL). Nasopharyngeal Swab: Place swab in Regan-Lowe
transport media and incubate for 24-48 hours at 35°C (ARUP supply# 24962). Available online through eSupply using ARUP Connect™ or
contact ARUP Client Services at (800) 522-2787. Also acceptable: Swab in Jones Kendrick media or Amies with charcoal media, or swabs in
described media sent directly without incubation.
Storage/Transport Temperature: Room temperature or refrigerated.
Unacceptable Conditions: Sputum, Eswabs or medias other than listed above.
Stability: Incubated Regan-Lowe: Ambient: 4 days; Refrigerated: 4 days; Frozen: Unacceptable
Unincubated Regan-Lowe, Amie with charcoal swab, Aspirate or Washing: Ambient: 48 hours; Refrigerated: 48 hours; Frozen: Unacceptable
CPT Code(s):
87081 presumptive identification. If definitive identification required, add 87077.
2004667
Bordetella pertussis DFA
PERTFA
Methodology:
Direct Fluorescent Antibody Stain
Specimen Required: Collect: Nasal aspirate or washing or nasopharyngeal swab.
Specimen Preparation: Aspirate or Washing: Transfer to a sterile container.(Min: 0.5 mL)
Nasopharyngeal Swab: Place swab in Regan-Lowe transport media and incubate for 24-48 hours at 35°C (ARUP supply# 24962). Available
online
through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. Also acceptable: Swab in Jones Kendrick media or
Aimes
with charcoal media, or swabs in described media sent directly without incubation.
If both culture and DFA are ordered, two swabs or swab plus slides are required.
Remarks: Source of specimen is preferred.
Unacceptable Conditions: Sputum. Swabs or media other than listed above.
Stability: Incubated Regan-Lowe: Ambient: 4 days; Refrigerated: 4 days; Frozen: Unacceptable.
Unincubated Regan-Lowe, Aimes with charcoal swab, Aspirate or Washing: Ambient: 48 hours; Refrigerated: 48 hours; Frozen:
Unacceptable.
Slides: Ambient: 1 week; Refrigerated: 1 week; Frozen: 1 month
CPT Code(s):
87265
0065080
Bordetella pertussis/parapertussis by PCR
BORD PCR
Methodology:
Specimen Required: Collect: Respiratory specimen: Aspirate, bronchoalveolar lavage (BAL), swab or sputum.
Specimen Preparation: Fluid: Transfer 2 mL respiratory specimen to a sterile container. (Min: 0.5 mL) Also acceptable: Transfer to viral transport
media (ARUP supply #12884). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787
Swabs: Place in viral transport media.
Unacceptable Conditions: Calcium-alginate swabs.
Stability: Ambient: 24 hours; Refrigerated: 5 days; Frozen: 2 weeks.
CPT Code(s):
87801
0091330
Boron, Serum or Plasma
BORON SP
Methodology:
Quantitative Inductively Coupled Plasma-Optical Emission Spectrometry
Specimen Required: Collect: Royal blue, plastic (trace metal-free; EDTA) or royal blue, plastic (trace metal-free; no additive).
Specimen Preparation: Separate from cells within 2 hours of draw. Transfer 2 mL serum or plasma to an ARUP Trace Element-Free Transport
Tube (ARUP supply #43116). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787.
(Min: 0.7 mL)
Unacceptable Conditions: Glass containers or separator tubes.
CPT Code(s):
83018
0091331
Methodology:
Boron, Urine
BORON URN
High concentrations of gadolinium are known to interfere with most metals tests. If gadolinium-containing contrast media
has been administered, a specimen cannot be collected for 48 hours.
Specimen Required: Collect: Random urine in a plastic trace metal-free or acid-washed container.
Specimen Preparation: Transfer 6 mL urine to ARUP Trace Element-Free Transport Tubes (ARUP supply #43116). Available online through
eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 2.7 mL)
Unacceptable Conditions: Glass containers.
Page | 119
CPT Code(s):
83018
0050254
Borrelia burgdorferi Antibodies, IgG & IgM by Western Blot
LYME WB
Methodology:
Qualitative Western Blot
Tube. (Min: 0.1 mL)
Unacceptable Conditions: CSF or plasma. Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimens.
CPT Code(s):
86617 Lyme IgG; 86617 Lyme IgM
0055260
Borrelia burgdorferi Antibodies, IgG & IgM by Western Blot (CSF)
Methodology:
Specimen Preparation: Transfer 3 mL CSF to an ARUP Standard Transport Tube. (Min: 2 mL)
CPT Code(s):
86617 B. burgdorferi IgG WB; 86617 B. burgdorferi IgM WB
LYME WBCSF
0050216
Borrelia burgdorferi Antibodies, Total by ELISA
LYME EIA
Methodology:
Tube. (Min: 0.1 mL)
Unacceptable Conditions: CSF. Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimens.
CPT Code(s):
86618
0099483
Borrelia burgdorferi Antibodies, Total by ELISA (CSF)
Methodology:
CPT Code(s):
86618
LYME CSF
0050267
Borrelia burgdorferi Antibodies, Total by ELISA with Reflex to IgG & IgM by Western Blot (Early Disease)
LYME ACUTE
Methodology:
Semi-Quantitative Enzyme-Linked Immunosorbent Assay/Qualitative Western Blot
Tube. (Min: 0.1 mL)
CPT Code(s):
86618 B. burgdorferi total Ab. IgG/IgM; if reflexed, add 86617 B. burgdorferi Western blot IgG and 86617 B. burgdorferi Western blot IgM
0050255
Borrelia burgdorferi Antibody, IgG by Western Blot
LYME G WB
Methodology:
Tube. (Min: 0.1 mL)
Unacceptable Conditions: CSF or plasma. Contaminated, heat-inactivated, hemolyzed, severely lipemic specimens.
CPT Code(s):
86617
0055259
Borrelia burgdorferi Antibody, IgG by Western Blot (CSF)
Methodology:
CPT Code(s):
86617
Page | 120
LYMEGWBCSF
0050253
Borrelia burgdorferi Antibody, IgM by Western Blot
LYME M WB
Methodology:
Tube. (Min: 0.1 mL)
CPT Code(s):
86617
0055258
Borrelia burgdorferi Antibody, IgM by Western Blot (CSF)
Methodology:
CPT Code(s):
86617
LYMEMWBCSF
0051044
Borrelia burgdorferi C6 Peptide Antibodies, Total by ELISA
C6 PEP
Methodology:
Specimen Preparation: Remove serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport
Tube. (Min: 0.1 mL)
Unacceptable Conditions: CSF. Contaminated, heat-inactivated, hemolyzed or lipemic specimens.
CPT Code(s):
86618
0051046
Borrelia burgdorferi C6 Peptide Antibodies, Total by ELISA (CSF)
Methodology:
Remarks: Indicate source on test requisition.
Unacceptable Conditions: Specimen types other than CSF. Contaminated or heat-inactivated specimens.
Stability: Ambient: 8 hours; Refrigerated: 2 weeks; Frozen 1 year
CPT Code(s):
86618
0051043
Borrelia burgdorferi C6 Peptide Antibodies, Total by ELISA with Reflex to IgG & IgM by Western Blot
Methodology:
Stability: After separation from cells: Ambient 48 hours; Refrigerated: 2 weeks; Frozen: 1 year
CPT Code(s):
86618 C6 Peptide; if positive add, 86617 x2 Lyme IgG/IgM
C6 PEP CSF
C6 ACUTE R
0051045
Borrelia burgdorferi C6 Peptide Antibodies, Total by ELISA with Reflex to IgG by Western Blot
C6 CHRON R
Methodology:
Tube. (Min: 0.2 mL)
CPT Code(s):
86618 C6 Peptide; if positive, add 86617 Lyme IgG
0050268
Borrelia burgdorferi Total Antibodies, IgG and/or IgM by ELISA with Reflex to IgG by Western Blot (Late
LYME CHRO
Disease)
Methodology:
Tube. (Min: 0.1 mL)
CPT Code(s):
86618 B. burgdorferi total Ab. IgG/IgM; if reflexed, add 86617 Borrelia burgdorferi Western blot IgG
0093170
Methodology:
Borrelia hermsii Antibody Panel, IFA
Semi-Quantitative Immunofluorescence Assay
(Indirect Fluorescent Antibody)
Specimen Preparation: Tranfer 1 mL serum to an ARUP Standard Transport Tube (Min: 0.25 mL)
CPT Code(s):
86619 IgG; 86619 IgM
Page | 121
BORRELIA
0055570
Borrelia Species by PCR (Lyme Disease)
LYMEPCR
Methodology:
Specimen Required: Collect: Lavender (EDTA), pink (K2EDTA) or serum separator tube. OR CSF, synovial fluid or tissue.
Specimen Preparation: Separate serum or plasma from cells. Transfer 1 mL serum, plasma, CSF or synovial fluid to a sterile container. (Min: 0.5
mL). Tissue: Transfer to a sterile container and freeze immediately.
Unacceptable Conditions: Heparinized specimens.
Stability: Tissue: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 1 year
All Others: Ambient: 8 hours; Refrigerated: 72 hours; Frozen: 1 year
CPT Code(s):
87476
2006297
Borrelia Species by PCR (Lyme Disease), Tick
Methodology:
Qualitative Real-Time Polymerase Chain Reaction
Specimen Required: Collect: Deer tick
Specimen Preparation: Transfer one deer tick in 70 percent ethanol or in wet tissue to an ARUP Standard Transport Tube.
CPT Code(s):
87476
LYME TICK
2002498
BRAF Codon 600 Mutation Detection by Pyrosequencing
BRAF PCR
Methodology:
Polymerase Chain Reaction/Pyrosequencing
Specimen Preparation: Formalin fix (10 percent neutral buffered formalin) and paraffin embed tissue. Protect from excessive heat. Transport
tissue block or 5 unstained 5-micron slides. (Min: 3 slides).
Unacceptable Conditions: Less than 25 percent tumor. Specimens fixed/processed in alternative fixatives (alcohol, Prefer®) or heavy metal
fixatives. Decalcified specimens.
CPT Code(s):
88381 Microdissection; 83907 Lysis; 83898 Amplification; 83904 Sequencing; 83912 Interpretation and report. Additional CPT code modifiers
may be required for procedures performed to test oncologic or inherited disorders.
0051750
BRAF Codon 600 Mutation Detection with Reflex to MLH1 Promoter Methylation
BRAF RFLX
Methodology:
Polymerase Chain Reaction/Pyrosequencing
microns slides. (Min: 3 slides). Protect paraffin block and/or slides from excessive heat.
Unacceptable Conditions: Less than 25 percent tumor. Specimens fixed/processed in alternative fixatives (alcohol, Prefer®) or heavy metal
fixatives. Decalcified specimens.
CPT Code(s):
83907 Lysis; 88381 Microdissection; 83904 Sequencing; 83898 Amplification; 83912 Interpretation and report; if reflexed, add 83896 x2 Nucleic
Acid Probes; 83898 x2 Amplification; 83912 Interpretation and report. Additional CPT code modifiers may be required for procedures performed
to test oncologic or inherited disorders.
2006516
BRAF V600E Mutation Detection by Allele-Specific PCR, Fine Needle Aspirate
BRAF FNA
Methodology:
Specimen Required: Collect: Tumor cells by Fine Needle Aspiration (FNA).
Specimen Preparation: Prepare FNA smear and Diff-Quick or equivalent stain by standard methods.
Storage/Transport Temperature: Two FNA slides (min: 1 slide) Transport slide(s) in a tissue transport kit (ARUP supply # 47808) available online
Remarks: Include cytology report. For a general FNA collection and smear preparation refer to ARUP's Laboratory Test Directory: Cytology, Fine
Needle Aspiration Collection at http://www.aruplab.com/guides/ug/tests/arup014.jsp
Unacceptable Conditions: Slides with less than 50 atypical or tumor cells.
CPT Code(s):
88381 Microdissection; 83907 Lysis; 83898 x2 Amplification; 83896 Nucleic acid probe; 83912 Interpretation and report. Additional CPT code
modifiers may be required for procedures performed to test oncologic or inherited disorders.
2007132
BRAF V600E Mutation Detection in Hairy Cell Leukemia by Real-Time PCR, Quantitative
BRAF HCL
Methodology:
Specimen Required: Collect: Lavender (EDTA) OR bone marrow (EDTA).
Specimen Preparation: Transport 5 mL whole blood. (Min: 1 mL) OR 3mL bone marrow (Min: 1 mL)
Unacceptable Conditions: Serum, plasma, FFPE tissue blocks/slides, or frozen tissue. Specimens collected in anticoagulants other than EDTA.
Clotted or severely hemolyzed specimens
CPT Code(s):
83891 Isolation; 83898 x2 Amplification; 83896 x2 Nucleic Acid Probe; 83912 Interpretation and report
2003472
Breast 2 (GCDFP-15) by Immunohistochemistry
BRST2 IHC
Methodology:
Page | 122
CPT Code(s):
88342
2003445
Breast Carcinoma b72.3 by Immunohistochemistry
B72.3 IHC
Methodology:
CPT Code(s):
88342
0091291
Bretylium, Serum or Plasma
Methodology:
Specimen Required: Collect: Plain red, gray (sodium fluoride/potassium oxalate), green (sodium heparin), or lavender (EDTA).
CPT Code(s):
80299
0096065
Bretylium, Urine
Methodology:
CPT Code(s):
80299
BRETYLIUM
BRETYLIU
0090035
Bromide
BR
Methodology:
Stability: After separation from cells: Ambient: 1 week; Refrigerated: 1 week; Frozen: Indefinitely
CPT Code(s):
80299
0060700
Bronchoscopy Culture
Methodology:
Quantitative Culture/Identification
Specimen Required: Collect: Lower respiratory material by bronchoscopy (BAL fluid or protected brush specimens).
Specimen Preparation: Transfer fluids to a sterile container.
Place each specimen in an individually sealed bag.
Stability: Ambient: Unacceptable; Refrigerated: 24 hours; Frozen: Unacceptable
CPT Code(s):
87071
MC BAL
0050135
Brucella Antibody (Total) by Agglutination
BRUC
Methodology:
Semi-Quantitative Agglutination
Stability: After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 6 months (avoid repeated freeze/thaw cycles)
CPT Code(s):
86622
0060159
Brucella Culture
MC BRUC
Methodology:
Specimen Required: Collect: Blood in sterile SPS Vacutainer® tube for microbiology (ARUP Supply #24964) or Bactec® Blood Culture bottles. Available online
through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. OR abscess, aspirate, body fluid, CSF, or tissues.
Specimen Preparation: Adult Blood: Transport 7 mL whole blood. (Min: 3 mL)*
Pediatric Blood: Transport 3 mL whole blood. (Min: 1 mL)*
Abscess, Aspirate, Body fluid, CSF: Transfer to a sterile container. Place each specimen in an individually sealed bag.
Page | 123
CPT Code(s):
Tissue: Transfer tissue to a sterile container and place on gauze moistened with sterile non-bacteriostatic saline to prevent drying.
*Low volume will result in decreased recovery of pathogens.
Unacceptable Conditions: Swabs. Specimens submitted in anticoagulant other than SPS. Clotted blood specimens.
2006218
Brugada Syndrome Panel, 7 Genes
BRS PANEL
Methodology:
CPT Code(s):
0092566
Bullous Pemphigoid (180 kDa and 230 kDa) Antigens, IgG
Methodology:
Enzyme-Linked Immunosorbent Assay
Unacceptable Conditions: Hemolyzed or lipemic specimens.
Stability: After separation from cells: Ambient: 72 hours; Refrigerated: 3 months; Frozen: Indefinitely
CPT Code(s):
83516 x2
BP180 230G
2002742
Buprenorphine and Metabolites - Confirmation/Quantitation - Serum/Plasma
BUPREN SP
Methodology:
Specimen Required: Collect: Gray (sodium fluoride/potassium oxalate). Also acceptable: Plain red, green (sodium heparin), lavender (EDTA), or pink (K2EDTA).
Standard Transport Tube. (Min: 1 mL)
Unacceptable Conditions: Separator tubes. Plasma or whole blood collected in lt. blue (sodium citrate). Specimens exposed to repeated
freeze/thaw cycles.
Stability: After separation from cells: Ambient: 1 week; Refrigerated: 2 weeks; Frozen: 3 years
CPT Code(s):
83925
2002749
Buprenorphine and Metabolites - Confirmation/Quantitation - Urine
BUPREN UR
Methodology:
Specimen Preparation: Transfer 2 mL urine with no additives or preservatives to an ARUP Standard Transport Tube. (Min: 1 mL)
Unacceptable Conditions: Specimens exposed to repeated freeze/thaw cycles.
Stability: Ambient: 1 week; Refrigerated: 1 month; Frozen: 3 years
CPT Code(s):
83925
0099184
Bupropion
BUPROPION
Methodology:
Remarks:
CPT Code(s):
80299
0091299
Methodology:
Buspirone Quantitation, Serum or Plasma
Recommended peak draw 40-90 minutes post dose.
Specimen Preparation: Transfer 5 mL serum or plasma to ARUP Standard Transport Tubes. (Min: 2.2 mL)
CPT Code(s):
80299
BUSPIRON
0091164
Buspirone, Urine
Methodology:
Gas Chromatography
Specimen Required: Collect: Urine. Recommended peak collection at 40-90 minutes post dose.
Remarks: Recommended peak occurs at 40 to 90 minutes post dose.
Stability: Ambient: 1 week; Refrigerated: 2 weeks: Frozen: 17 months
CPT Code(s):
82491
BUSPIRO U
Page | 124
0090980
Butabarbital, Serum or Plasma
Methodology:
CPT Code(s):
82205
0091170
Butabarbital, Urine
Methodology:
CPT Code(s):
82205
BUTABAR SP
BUTABA UR
0090045
Butalbital
BUTAL
Methodology:
Quantitative Gas Chromatography-Mass Spectrometry
Stability: After separation from cells: Ambient: 3 months; Refrigerated: 3 months; Frozen: 1 year
CPT Code(s):
82205
0091521
Methodology:
Butorphanol, Serum or Plasma - Screen with Reflex to Confirmation/Quantitation
STADOL SP
Qualitative High Performance Liquid Chromatography-Tandem Mass Spectrometry/Quantitative High Performance Liquid ChromatographyTandem Mass Spectrometry
Stability: Ambient: 1 week; Refrigerated: 10 days; Frozen: 1 month
CPT Code(s):
80101 Drug screen, if positive, add 83925
0091520
Methodology:
Butorphanol, Urine - Screen with Reflex to Confirmation/Quantitation
STADOL UR
Qualitative High Performance Liquid Chromatography-Tandem Mass Spectrometry/Quantitative High Performance Liquid ChromatographyTandem Mass Spectrometry
Stability: Ambient: 1 week; Refrigerated: 10 days; Frozen: 1 month
CPT Code(s):
80101 Drug screen; if positive, add 83925
0050139
C-1-Esterase Inhibitor Panel
C1 INH PAN
Methodology:
Immunoturbidimetry/Semi-Quantitative Enzyme-Linked Immunosorbent Assay/Quantitative Nephelometry
Specimen Preparation: Separate serum from cells ASAP or within 2 hours of collection. Transfer three 1 mL aliquots of serum to individual
ARUP Standard Transport Tubes and freeze immediately. (Min: 0.5 mL/tube)
Stability: Refer to individual components.
CPT Code(s):
86160 Complement C4; 86160 C-1-Esterase inhibitor; 86161 C-1 Esterase inhibitor functional
0081121
C-Peptide, 24-Hour Urine
CPEP UR
Methodology:
Specimen Required: Collect: 24-hour urine. Refrigerate during collection. Also acceptable: Random urine (no reference intervals).
Specimen Preparation: Transfer 2 mL aliquot from a well-mixed 24-hour urine to an ARUP Standard Transport Tube. (Min: 0.5 mL)
CPT Code(s):
84681
0070103
Methodology:
C-Peptide, Serum or Plasma
C PEP
Fasting specimen preferred.
Specimen Required: Collect: Serum separator tube or plasma separator tube. Also acceptable: Green (sodium or lithium heparin), lavender (EDTA), or pink
(K2EDTA).
Specimen Preparation: Allow specimen to clot completely at room temperature. Separate serum or plasma from cells ASAP. Submit specimen in
an ARUP Standard Transport Tube.
Storage/Transport Temperature: Transport 1 mL serum or plasma, frozen. (Min: 0.5 mL)
Stability: After separation from cells: Ambient: 8 hours; Refrigerated: 2 days; Frozen: 1 month
CPT Code(s):
84681
Page | 125
0050180
C-Reactive Protein
Methodology:
Specimen Required: Collect: Serum separator tube. Also acceptable: Plasma separator tube, green (lithium heparin), lavender (EDTA), or pink (K2EDTA).
collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL)
Stability: After separation from cells: Ambient: 11 days; Refrigerated: 2 months; Frozen: 3 years (if frozen within 24 hours)
CPT Code(s):
86140
CRP
0050182
C-Reactive Protein, High Sensitivity
HSCRP
Methodology:
Specimen Required: Collect: Serum separator tube. Also acceptable: Plasma separator tube, lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin).
Stability: After separation from cells: Ambient: 48 hours; Refrigerated: 2 months; Frozen: 1 year
CPT Code(s):
86141
0050181
C-Reactive Protein, Neonatal
CRPN
Methodology:
Immunoassay
Specimen Required: Collect: Plasma separator tube (PST) microtainer. Also acceptable: Serum separator tube (SST), lavender (EDTA) or pink (K2EDTA).
Specimen Preparation: Separate plasma or serum from cells within 2 hours of collection. If serum is used allow specimen to clot completely at
room temperature. Transport 0.2 mL serum. (Min: 0.1 mL)
Stability: After separation from cells: Ambient: 11 days; Refrigerated: 2 months; Frozen: 3 years
CPT Code(s):
86140
0070416
Methodology:
C-Telopeptide, Beta-Cross-Linked, Serum
CTX
For patients receiving therapy with high biotin doses (e.g. greater than 5 mg/day), specimen should not be drawn until at
least 8 hours after the last biotin administration.
Specimen Required: Collect: Serum separator tube, pink (K2EDTA), or green (sodium heparin).
Specimen Preparation: Allow serum separator tube to sit for 15-20 minutes at room temperature for proper clot formation. Centrifuge and separate
serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min:
0.5 mL)
CPT Code(s):
82523
0050140
C1-Esterase Inhibitor
C1ESTER
Methodology:
Tube. (Min: 0.4 mL)
Stability: After separation from cells: Ambient: 2 hours; Refrigerated: Unacceptable; Frozen: 2 weeks
CPT Code(s):
86160
0050141
C1-Esterase Inhibitor Functional
C1 INH F
Methodology:
Specimen Required: Collect: Serum separator tube lavender (EDTA), or pink (K2EDTA).
CPT Code(s):
86161
0050301
C1q Binding Assay
C1Q
Methodology:
Specimen Preparation: Let stand on clot for two hours. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL) If ordered in
conjunction with a Raji Cell Assay, transfer two 1 mL aliquots of serum to individual ARUP Standard Transport Tubes.
Stability: After separation from cells: Ambient: 2 hours; Refrigerated: Unacceptable; Frozen: 2 weeks (avoid repeated freeze/thaw cycles)
CPT Code(s):
86332
2003475
C4D by Immunohistochemistry
Methodology:
Page | 126
C4D IHC
CPT Code(s):
88342
0099675
Methodology:
Cadmium, Blood
CADMIUM B
discontinue nutritional supplements, vitamins, minerals, non-essential over-the-counter medications (upon the advice of their physician).
CPT Code(s):
82300
0025013
Methodology:
Cadmium Exposure Panel - OSHA
CD EXP
Cadmium, Urine & Blood: Quantitative Inductively Coupled Plasma-Mass Spectrometry
Urine: Spectrophotometry
Urine: Chemiluminescent Immunoassay
Specimen Required: Collect: Royal blue (K2EDTA or Na2EDTA) AND minimum 40 mL urine using spot technique (single void) in an open-top urine collection cup.
To avoid contamination, please collect specimens at the beginning of work shift. Blood and urine should be collected the same day.
Specimen Preparation: Blood: Transport 7 mL whole blood.
Urine for -2-Microglobulin: Transfer aliquot from original urine collection to an ARUP Standard Transport Tube. Adjust the pH of this
specimen immediately after pouring off collection so that the pH is between 6 and 8. Use 1M HCl or 5% NaOH to adjust the urine pH. Label tube
as -2-Microglobulin. Freeze within one hour of collection.
Urine for Cadmium: Transfer aliquot from original urine collection to an ARUP Standard Transport Tube. Add 0.1 mL of the 12M HNO3 to the
aliquot. Label tube as Cadmium.
Urine for Creatinine: Transfer aliquot from original urine collection to an ARUP Standard Transport Tube. Label tube as Creatinine.
Storage/Transport Temperature: Blood: Refrigerated.
Urine for -2-Microglobulin: Frozen.
Urine for Cadmium: Refrigerated.
Urine for Creatinine: Refrigerated.
MRI studies).
CPT Code(s):
82300 Cadmium, blood; 82300 Cadmium, urine; 82232 2 Microglobulin; 82570 Creatinine, Urine
0025040
Methodology:
Cadmium, Urine
CADMIUM U
CPT Code(s):
82300
0090050
Caffeine
CAF
Methodology:
Quantitative Enzyme Multiplied Immunoassay Technique
Specimen Required: Collect: Plain red. Also acceptable: Lavender (EDTA), pink (K2EDTA or K3EDTA), green (sodium or lithium heparin), or gray (sodium
fluoride/potassium oxalate). Also acceptable (avoid if possible): Serum separator tube or plasma separator tube (follow preparation instructions
below).
Specimen Preparation: Separate serum or plasma from cells within 6 hours of collection. Transfer 0.5 mL serum or plasma to an ARUP Standard
SST or PST: Serum or plasma in a gel separator tube stored at room temperature is acceptable if separated from the gel within 6 hours. Serum or
plasma in a gel separator tube stored refrigerated is acceptable if separated from the gel within 2 hours.
Unacceptable Conditions: Citrated plasma. Tubes that contain liquid anticoagulant.
CPT Code(s):
80299
0070006
Methodology:
Page | 127
Calcitonin
CALCI
Standard Transport Tube. (Min: 1 mL)
Unacceptable Conditions: Tissue or urine. EDTA plasma. Grossly hemolyzed or lipemic specimens.
CPT Code(s):
82308
2003481
Calcitonin by Immunohistochemistry
CALCIT IHC
Methodology:
CPT Code(s):
88342
0020135
Calcium, Ionized, Serum
IONCA-S
Methodology:
Ion-Selective Electrode/pH Electrode
Specimen Preparation: Do not open the tube or split the specimen. Do not freeze separator tube. Do not expose specimen to air at any time
during collection or transport process. Centrifuge with stopper in place within one hour of collection. Transport 5 mL serum in original serum
separator tube. (Min: 0.5 mL)
Storage/Transport Temperature: Refrigerated. Ship upright in original serum separator collection tube and transport in the ARUP shipping rack.
Do not ship on dry ice.
CPT Code(s):
82330
0020140
Calcium, Ionized, Whole Blood
Methodology:
Ion-Selective Electrode/pH Electrode
Specimen Required: Collect: Testing available to UUHC clients only.
Green (sodium or lithium heparin). Collect on ice.
Pediatric Collect: 2 full heparinized capillary tubes (call lab for tube).
Specimen Preparation: Do not freeze. Transport minimum 0.5 mL specimen.
Pediatric Specimen Preparation: Transport 2 full heparinized capillary tubes.
Storage/Transport Temperature: Deliver to lab within 10 minutes on wet ice.
Unacceptable Conditions: Frozen or room temperature specimens.
Stability: Ambient: Unacceptable; Refrigerated: 4 hours; Frozen: Unacceptable
CPT Code(s):
82330
IONCA-WB
0020027
Calcium, Serum or Plasma
Methodology:
Specimen Required: Collect: Serum separator tube or plasma separator tube. Do not use powdered gloves during collection.
Unacceptable Conditions: Specimens from patients receiving EDTA therapy or Hypaque. EDTA, citrate, or oxalate.
CPT Code(s):
82310
CA
0020472
Calcium, Urine
UCA
Methodology:
Specimen Required: Collect: 24-hour urine specimens. Urine must be refrigerated during collection. Also acceptable: Random urine.
Specimen Preparation: Adjust pH to 1.5-2.0 by adding 6M HCl in 1 mL increments. Transfer one 3 mL aliquot from a well-mixed 24-hour
collection to an ARUP Standard Transport Tube. (Min: 0.5 mL) Record total volume, collection time interval, and pH on transport tube and test
request form.
Stability: Ambient: 48 hours; Refrigerated: 4 days; Frozen: 3 weeks
CPT Code(s):
82340
0099460
Calculi (Stone) Analysis
CALCULI
Methodology:
Quantitative Reflectance Fourier Transform Infrared Spectroscopy/Quantitative Polarizing Microscopy
Specimen Required: Collect: Calculi specimen.
Specimen Preparation: Air-dry calculi and transfer to an ARUP Standard Transport Tube. Larger calculi specimens may be transferred to a
clean, empty urine cup (150 mL) or similar container.
Storage/Transport Temperature: Room temperature. Also acceptable: Frozen or refrigerated.
Remarks: Calculi specimens transported in liquid or contaminated with blood require special handling which will delay analysis. Specimens that
are wrapped in tape or embedded in wax will delay or prevent analysis and should not be submitted.
Unacceptable Conditions: Any collection or shipping container with a needle attached.
Stability: Ambient: Indefinitely; Refrigerated: Indefitnitely; Frozen: Indefinitely
CPT Code(s):
82365
Page | 128
2005231
Calculi (Stone) Analysis with Photo
CALCPHOTO
Methodology:
Quantitative Reflectance Fourier Transform Infrared Spectroscopy/Quantitative Polarizing Microscopy
Specimen Required: Collect: Calculi specimen greater than 2 mg.
Specimen Preparation: Air dry calculi and transfer to an ARUP Standard Transport Tube. Larger calculi specimens may be transported in a
clean, empty urine cup (150 mL) or similar container.
Remarks: Calculi specimens that are transported in liquid and received wet or bloody will be dried for 48-72 hours, which will cause a delay in
processing.
Unacceptable Conditions: Specimens that are wrapped in tape or embedded in wax will delay or prevent analysis and should not be submitted.
Stability: Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Indefinitely
CPT Code(s):
82365
2003484
Caldesmon by Immunohistochemistry
CALDES IHC
Methodology:
CPT Code(s):
88342
0098893
California Encephalitis Antibody, IgG by IFA, CSF
Methodology:
CPT Code(s):
86651
CAL G CSF
0050508
California Encephalitis Antibody, IgG by IFA, Serum
CALIF
Methodology:
specimens. Please mark specimens plainly as acute or convalescent.
Unacceptable Conditions: Contaminated, hemolyzed, severely lipemic specimens.
CPT Code(s):
86651
0098898
California Encephalitis Antibody, IgM by IFA, CSF
Methodology:
CPT Code(s):
86651
CAL M CSF
0098731
California Encephalitis Antibody, IgM by IFA, Serum
CAL M SER
Methodology:
Specimen Preparation: Remove from serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard
Transport Tube. (Min: 0.15 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the
acute specimens. Mark specimens plainly as acute or convalescent.
Unacceptable Conditions: Plasma. Heparinized specimens. Contaminated, heat-inactivated, or severely lipemic specimens.
CPT Code(s):
86651
2003487
Calponin by Immunohistochemistry
CALPON IHC
Methodology:
Page | 129
CPT Code(s):
88342
0092303
Calprotectin, Fecal
CALPRO
Methodology:
ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 1 g)
Stability: Ambient: 5 days; Refrigerated: 5 days; Frozen: 1 year
CPT Code(s):
83993
2003490
Calretinin by Immunohistochemistry
CALRET IHC
Methodology:
CPT Code(s):
88342
0058002
Campylobacter Antigen
CAMPY
Methodology:
Qualitative Immunochromatography
Specimen Preparation: Transfer 5 g stool to an unpreserved stool transport vial (ARUP supply #40910).OR place 5 g stool in enteric transport
media (Cary-Blair) within one hour of collection (ARUP supply #29799). (Min: 1 g)
Unacceptable Conditions: Specimens in any transport media other than indicated above.
Stability: Ambient: Unacceptable; Refrigerated: 4 days; Frozen: 2 weeks
CPT Code(s):
87899
0098841
Campylobacter jejuni Antibody, IgG
CAMP JEJ
Methodology:
Specimen Preparation: Separate serum or plasma from cells ASAP or within 2 hours of collection. Transport 1 mL serum. (Min: 0.15 mL)
CPT Code(s):
86625
0051454
Canavan (ASPA) 4 Mutations, Fetal
ASPA FE
Methodology:
CPT Code(s):
83891 Isolation; 83892 x2 Digestion; 83900 Multiplex amplification (first two amplifications); 83901 Additional amplification; 83914 x5
Extension; 83909 Capillary electrophoresis; 83912 Interpretation and report. FCC: 83900 Multiplex amplification (first two sequences); 83901
x14 Additional amplification; 83909 Capillary electrophoresis. If MCC MAT (0050608) is performed: 83891 Isolation; 83900 Multiplex
amplification; 83901 x14 Additional amplification; 83909 Capillary electrophoresis; 83912 Interpretation and report - Additional CPT code
0051453
Canavan Disease (ASPA) 4 Mutations
Methodology:
Page | 130
ASPA
CPT Code(s):
83891 Isolation; 83892 x2 Enzymatic digestion; 83900 Amplification multiplex (first two amplifications); 83901 Amplification multiplex (each
additional amplification) 83914 x5 Mutation identification; 83909 Separation and identification; 83912 Interpretation and report - Additional CPT
0080392
Cancer Antigen 27.29
CA27.29
Methodology:
CPT Code(s):
86300
0080462
Cancer Antigen 125
CA125
Methodology:
Specimen Required: Collect: Plasma separator tube or serum separator tube. Also acceptable: Green (sodium or lithium heparin), lavender (EDTA), or pink (K2EDTA).
CPT Code(s):
86304
2003478
Cancer Antigen 125 by Immunohistochemistry
CA125 IHC
Methodology:
CPT Code(s):
88342
0080464
Cancer Antigen-Breast (CA 15-3)
CA-BREAST
Methodology:
(K2EDTA).
CPT Code(s):
86300
0080461
Cancer Antigen-GI (CA 19-9)
CA-GI
Methodology:
(K2EDTA).
Unacceptable Conditions: Body Fluid (refer to Cancer Antigen-GI (CA19-9), Body Fluid, ARUP test code 0020746). Specimens collected in
sodium citrate.
CPT Code(s):
86301
0020746
Cancer Antigen-GI (CA 19-9), Body Fluid
Methodology:
Specimen Preparation: Transport 1 mL body fluid. (Min: 0.5 mL)
Stability: Ambient: 8 hours; Refrigerated: 5 days; Frozen: 3 months
CPT Code(s):
86301
CA-GI FL
0095200
Candida albicans Antibodies IgA, IgG, and IgM by ELISA
CANDIDA AB
Methodology:
Tube (Min: 0.1 mL)
Page | 131
CPT Code(s):
86628 x3
0055565
Candida Antibody by ID
CAN PPT
Methodology:
Unacceptable Conditions: Body fluids.
CPT Code(s):
86628
0091339
Canrenone, Serum or Plasma
Methodology:
Spectrofluorometry
Specimen Preparation: Protect from light. Transfer 1 mL serum or plasma to an ARUP Amber Transport Tube.
Unacceptable Conditions: Specimens not protected from light.
CPT Code(s):
80299
CANRENON
0091502
Canrenone, Urine
Methodology:
Spectrofluorometry
Specimen Preparation: Transfer 2 mL urine to an ARUP Standard Transport Tube.
CPT Code(s):
80299
CANREN UR
0091166
Carbamazepine - 10,11 Epoxide, Urine
Methodology:
CPT Code(s):
80156
CARB EP U
0092211
Methodology:
Carbamazepine Epoxide and Total
CARB EPOXT
Quantitative Liquid Chromatography-Tandem Mass Spectrometry/Quantitative Enzyme Multiplied Immunoassay Technique
Obtain trough specimen after steady-state is achieved (3-5 days). Draw within one hour prior to next dose. The epoxide
half-life is 6-10 hours.
CPT Code(s):
80156; Carbamazepine, total; 80299 Carbamazepine, Epoxide
0090615
Carbamazepine, Free and Total
FCARB
Methodology:
Quantitative Enzyme Multiplied Immunoassay Technique
Specimen Required: Collect: Plain red. Also acceptable (avoid if possible): Serum separator tube (follow preparation instructions below).
Specimen Preparation: Separate serum from cells within 2 hours of collection. Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min:
1 mL)
Remarks: Separate serum from cells ASAP.
Unacceptable Conditions: Citrated plasma. Tubes that contain liquid anticoagulant.
Stability: After separation from cells: Ambient: 5 days; Refrigerated: 5 days; Frozen: 4 months
CPT Code(s):
80156 Carbamazepine, total; 80157 Carbamazepine, free
0090260
Carbamazepine, Total
TEG
Methodology:
Enzyme Immunoassay
Specimen Preparation: Allow specimen to clot completely at room temperature. Ensure complete clot formation has taken place prior to
centrifugation. Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube.
(Min: 0.5 mL)
Unacceptable Conditions: Separator tubes or potassium oxalate/sodium fluoride tubes. EDTA plasma.
Stability: After separation from cells: Ambient: 2 days; Refrigerated: 7 days; Frozen: 1 month
CPT Code(s):
80156
0091352
Carbidopa and Levodopa Quantitation, Serum or Plasma
SINEMET SP
Methodology:
Specimen Preparation: Separate serum or plasma from cells within 2 hours of draw. Transfer 2 mL serum or plasma to an ARUP Standard
Page | 132
CPT Code(s):
Stability: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 1 week
80299
0070412
Carbohydrate Deficient Transferrin for Alcohol Use
Methodology:
Quantitative Electrophoresis
Unacceptable Conditions: Plasma. Hemolyzed specimens.
Stability: After separation from cells: Ambient: Unacceptable; Refrigerated: 10 days; Frozen: 1 month
CPT Code(s):
82373
2002918
Carbohydrate Deficient Transferrin for Congenital Disorders of Glycosylation
Methodology:
Affinity Chromatography/Mass Spectrometry
Remarks: Patient age is required on the test request form. Provide reason (eg, diagnosis) for referral with each specimen.
Stability: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 1 week
CPT Code(s):
82373
CDT
CARBOH-CDG
0020004
Carbon Dioxide, Serum or Plasma
CO2
Methodology:
collection. Transport 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.2 mL)
Unacceptable Conditions: Other body fluids. Specimens containing citrate as anticoagulant.
Stability: After separation from cells: Ambient: 4 hours; Refrigerated: 1 week (in a closed container); Frozen: 1 month (in a closed container)
CPT Code(s):
82374
2005757
Carboxyhemoglobin Quantitation, Whole Blood by Co-Oximetry
CARBOXY HB
Methodology:
Spectrophotometry
Specimen Required: Collect: Green (sodium or lithium heparin). Do not collect by finger stick or heel stick. Collect Sunday-Thursday only.
Specimen Preparation: Keep specimen anaerobic; do not remove cap from collection tube. Refrigerate within 30 minutes after collection.
Transport 5 mL whole blood. (Min: 0.5 mL) Specimen should be received within 24 hours of collection.
Storage/Transport Temperature: Refrigerated. Separate specimens must be submitted when multiple tests are ordered. Ship Sunday- Thursday
only.
Unacceptable Conditions: Specimens collected in EDTA tubes or not anaerobically. Specimens that have been opened or exposed to room air.
Frozen or room temperature specimens. Specimens containing air bubbles or clots.
Stability: Ambient: Unacceptable; Refrigerate: 72 hours; Frozen: Unacceptable
CPT Code(s):
82375
0080080
Carcinoembryonic Antigen
CEA
Methodology:
Unacceptable Conditions: Body Fluid (refer to Carcinoembryonic Antigen, Fluid, ARUP test code 0020742). Plasma.
CPT Code(s):
82378
0020742
Carcinoembryonic Antigen, Fluid
Methodology:
Specimen Preparation: Transfer 1 mL body fluid to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Remarks: Indicate a source on test request form.
CPT Code(s):
82378
CEA FL
2003824
Carcinoembryonic Antigen, Monoclonal (CEA M) by Immunohistochemistry
CEA M IHC
Methodology:
CPT Code(s):
88342
Page | 133
2003827
Carcinoembryonic Antigen, Polyclonal (CEA P) by Immunohistochemistry
CEA P IHC
Methodology:
CPT Code(s):
88342
0051600
Cardiolipin and Non-Criteria Anti-Phospholipid Syndrome (APS) Antibody Panel
PHOS PAN
Methodology:
Tube. (Min: 1.2 mL)
Unacceptable Conditions: Urine or plasma. Contaminated, heat-inactivated, grossly hemolyzed, icteric, or lipemic specimens.
CPT Code(s):
86147 x3 aCL IgG, IgM, & IgA; 86148 x3 aPS IgG, IgM, & IgA; 83520 x9 aPE, aPG, aPI IgG, IgM, & IgA
0099344
Cardiolipin Antibodies, IgG and IgM
ANTI-CARD
Methodology:
Tube. (Min: 0.3 mL)
Unacceptable Conditions: Plasma or other body fluids. Contaminated, heat-inactivated, hemolyzed, or lipemic specimens.
Stability: After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen 1 year (avoid repeated freeze/thaw cycles)
CPT Code(s):
86147 x2
0051162
Cardiolipin Antibodies, IgG, IgM, and IgA
CARD PAN
Methodology:
Tube. (Min: 0.3 mL)
CPT Code(s):
86147 AC-IgG; 86147 AC-IgM; 86147 AC-IgA
0098358
Cardiolipin Antibody, IgA
CARDIO IGA
Methodology:
Tube. (Min: 0.3 mL)
CPT Code(s):
86147
0050901
Cardiolipin Antibody, IgG
AC-IGG
Methodology:
Tube. (Min: 0.3 mL)
CPT Code(s):
86147
0050902
Cardiolipin Antibody, IgM
AC-IGM
Methodology:
Tube. (Min: 0.3 mL)
CPT Code(s):
86147
0090600
Carisoprodol and Meprobamate
Methodology:
Gas Chromatography-Mass Spectrometry
Page | 134
CARIS
CPT Code(s):
Stability: After separation from cells: Ambient: 1 week; Refrigerated: 1 month; Frozen: 3 months
83805 Meprobamate; 80299 Carisoprodol
2007234
Carisoprodol and Metabolite, Urine
Methodology:
Quantitative Gas Chromatography-Mass Spectrometry
Specimen Required: Collect: Urine
Specimen Preparation: Transport 2 mL urine in an ARUP Standard Transport Tube. (Min: 0.7 mL)
Storage/Transport Temperature: Refrigerated. Also acceptable: Room temperature or frozen
CPT Code(s):
80299 Carisoprodol; 83805 Meprobamate
CARIS URN
0080065
Carnitine, Free
CARN
Methodology:
Specimen Preparation: Separate serum or plasma from cells and freeze ASAP or within 2 hours of collection. Transfer 0.5 mL serum or plasma to
an ARUP Standard Transport Tube and freeze immediately. (Min: 0.2 mL) Avoid hemolysis.
Unacceptable Conditions: Room temperature specimens. Specimens that have been refrigerated for greater than 12 hours.
CPT Code(s):
83789
0080068
Carnitine, Free & Total (Includes Carnitine, Esterified)
CARN F&T
Methodology:
Unacceptable Conditions: Room temperature specimens. Specimens refrigerated greater than 12 hours.
CPT Code(s):
82379
0081308
Carnitine, Free & Total, Urine
CARN URINE
Methodology:
Specimen Preparation: Freeze specimen immediately after collection. Transport 5 mL urine. (Min: 2 mL)
CPT Code(s):
82379
0081309
Carnitine, Free, Urine
CARNU FREE
Methodology:
CPT Code(s):
83789
0081110
Carnitine Panel
CARNPAN
Methodology:
Specimen Preparation: Separate plasma or serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum or plasma to an ARUP
CPT Code(s):
82017 Acylcarn; 82379 Carnitine
0080067
Carnitine, Total
CARN TOTAL
Methodology:
Stability: Ambient: Unacceptable; Refrigerated: 12 hours; Frozen: 1 month (avoid repeated freeze thaw cycles)
CPT Code(s):
83789
0081307
Methodology:
Page | 135
Carnitine, Total, Urine
CARNU TOT
CPT Code(s):
83789
0080512
Carnitine Transport, Fibroblasts
CARNIFIBRO
Methodology:
Radioassay
Specimen Required: Collect: Fibroblasts from skin biopsy.
Specimen Preparation: Cells should be kept in 37°C incubator until shipped. Transport two T-25 flasks of fibroblasts from skin biopsy.
Storage/Transport Temperature: CRITICAL ROOM TEMPERATURE. Call lab before shipping. Ship Monday-Thursday only.
Unacceptable Conditions: Frozen or refrigerated specimens. Specimens in improper media. Dead cells.
Stability: Ambient: 4 days; Refrigerated: Unacceptable; Frozen: Unacceptable
CPT Code(s):
84238
0080055
Methodology:
Carotene, Serum Total
CARO
Fasting specimens preferred.
Specimen Preparation: CRITICAL: Protect from light immediately after collection and during storage and shipment. Transfer 3 mL serum to
ARUP Amber Transport Tube. (Min: 1.1 mL)
Storage/Transport Temperature: Frozen. Separate specimens must be submitted when multiple tests are ordered.
Unacceptable Conditions: Any specimen other than serum. Refrigerated or room temperature specimens. Hemolyzed or icteric specimens.
CPT Code(s):
82380
0021021
Methodology:
Carotenes, Fractionated, Plasma or Serum
CARO FRAC
Patient should fast overnight for 12 hours and should not consume alcohol for 24 hours prior to blood draw.
Specimen Preparation: CRITICAL: Protect from light within one hour of collection and during storage and shipment. Transfer 1 mL serum or
plasma to an ARUP Amber Transport Tube ASAP or within 2 hours of collection. (Min: 0.3 mL)
Storage/Transport Temperature: Frozen. Separate specimens must be submitted when multiple tests are ordered.
Unacceptable Conditions: EDTA plasma, whole blood, or body fluids. Room temperature specimens. Hemolyzed specimens.
Stability: After separation from cells: Ambient: Unacceptable; Refrigerated: 72 hours; Frozen: 1 year
CPT Code(s):
82380
2003496
Caspase-3 by Immunohistochemistry
CASPA3 IHC
Methodology:
Unacceptable Conditions: Depleted specimens. Specimens submitted with non-representative tissue type.
Stability: Ambient: Indefinite; Refrigerated: Indefinite; Frozen: Unacceptable
CPT Code(s):
88342
2006224
Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) Panel, 3 Genes
CPVT PANEL
Methodology:
Sequencing
CPT Code(s):
0080407
Methodology:
Catecholamines Fractionated by LC-MS/MS, Urine Free
CATE UF
Abstain from medications for 72 hours prior to collection.
Specimen Required: Collect: 24-hour or random urine. Refrigerate 24-hour specimen during collection.
Specimen Preparation: Transfer a 4 mL aliquot from a well-mixed 24-hour or random collection to an ARUP Standard Transport Tube. (Min: 2.5
mL) Preservation can be enhanced by adjusting the pH to 2-3 by adding an acid such as 6 mol/L HCl. Catecholamines are not stable above pH 7.
The pH of such specimens must be adjusted by the addition of acid prior to transport. A pH less than 2 can cause assay interference. Record total
volume and collection time interval on transport tube and test request form.
Stability: Ambient: Unacceptable; Refrigerated: 1 month; Frozen: 6 months
CPT Code(s):
82384
Page | 136
0080957
Methodology:
Catecholamines Fractionated (Epinephrine, Norepinephrine), Plasma
CATE PF,EN
Patient should be calm and supine for 30 minutes prior to collection.
Specimen Preparation: Specimen should be centrifuged and frozen within one hour (refrigerated centrifuge is preferred but not required). Transfer
4 mL plasma to an ARUP Standard Transport Tube. (Min: 2.1 mL)
Unacceptable Conditions: EDTA plasma, serum, or urine.
Stability: After separation from cells: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen at -20°C: 1 month; Frozen at -70°C: 1 year
CPT Code(s):
82384
0080216
Methodology:
Catecholamines Fractionated, Plasma
CATE PF
Patient should be calm and supine for 30 minutes prior to collection.
Specimen Preparation: Specimen should be centrifuged and frozen within one hour (refrigerated centrifuge is preferred but not required). Transfer
4 mL plasma to an ARUP Standard Transport
Tube. (Min: 2.1 mL)
Unacceptable Conditions: EDTA plasma, serum, or urine.
Stability: After separation from cells: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen at -20°C: 1 month; Frozen at -70°C: 1 year
CPT Code(s):
82384
0040002
CBC with Platelet Count
Methodology:
Automated Cell Count
Unacceptable Conditions: Frozen specimens. Clotted or hemolyzed specimens.
Stability: Ambient: 8 hours; Refrigerated: MPV: 8 hours, All Others: 24 hours; Frozen: Unacceptable
CPT Code(s):
85027
CBC
0040003
CBC with Platelet Count and Automated Differential
CBCAD
Methodology:
Automated Cell Count/Differential
Specimen Required: Collect: Lavender (EDTA) or pink (K2EDTA) AND unstained whole blood smears.
Specimen Preparation: Transport 3 mL whole blood AND 2 unstained whole blood smears. (Min: 0.5 mL. Tube must contain at least 0.25 mL of
specimen AND two unstained blood smears.)
Unacceptable Conditions: Frozen specimens. Clotted or grossly hemolyzed specimens.
Stability: Ambient: 8 hours (without smears); Refrigerated: MPV: 8 hours, All others: 24 hours; Frozen: Unacceptable
CPT Code(s):
85025
0092209
CBFB-MYH1, inv(16) by RT-PCR
INV(16)
Methodology:
CPT Code(s):
83891 Isolation; 83902 Reverse transcription; 83898 x5 Amplification; 83894 x3 Gel separation; 83912 Interpretation and report - Additional CPT
2003502
CD1a by Immunohistochemistry
CD1A IHC
Methodology:
CPT Code(s):
88342
2003505
CD2 by Immunohistochemistry
CD2 IHC
Methodology:
Page | 137
CPT Code(s):
88342
2003508
CD3 IHC
Methodology:
details, please contact ARUP Client Services at (800) 522-2787.
CPT Code(s):
88342
2003511
CD4 IHC
Methodology:
CPT Code(s):
88342
2003514
CD5 IHC
Methodology:
CPT Code(s):
88342
2003517
CD7 IHC
Methodology:
CPT Code(s):
88342
2003520
CD8 IHC
Methodology:
Page | 138
CPT Code(s):
88342
2003523
CD10 (CALLA) by Immunohistochemistry
CD10 IHC
Methodology:
CPT Code(s):
88342
2003526
CD14 IHC
Methodology:
CPT Code(s):
88342
2003529
CD15, Leu M1 by Immunohistochemistry
CD15 IHC
Methodology:
CPT Code(s):
88342
2005114
CD19 IHC
Methodology:
CPT Code(s):
88342
2003532
CD20, L26 by Immunohistochemistry
CD20 IHC
Methodology:
Stability: Ambient: Indefinite, Refrigerated: Indefinite, Frozen: Unacceptable
CPT Code(s):
88342
Page | 139
2003535
CD21 (Dendritic Cell) by Immunohistochemistry
CD21 IHC
Methodology:
CPT Code(s):
88342
2003541
CD23 IHC
Methodology:
Stability: Ambient: Indefinite, Refrigerated: Indefinite, Frozen: Unacceptable
CPT Code(s):
88342
2003544
CD25 IHC
Methodology:
CPT Code(s):
88342
2003547
CD30 (Ki-1) by Immunohistochemistry
CD30 IHC
Methodology:
details, please contact ARUP Client Services.
Stability: Ambient: Indefinite; Refrigerated: Indefinite; Frozen: Indefinite
CPT Code(s):
88342
2003550
CD31 IHC
Methodology:
CPT Code(s):
88342
2003553
Methodology:
Page | 140
CD33 IHC
CPT Code(s):
88342
2003556
CD34, QBEnd/10 by Immunohistochemistry
CD34 IHC
Methodology:
CPT Code(s):
88342
2003559
CD35 IHC
Methodology:
CPT Code(s):
88342
2003565
CD42b by Immunohistochemistry
CD42b IHC
Methodology:
Stability: Ambient: Indefinite, Refrigerated: Indefinite, Frozen: Indefinite
CPT Code(s):
88342
2003568
CD43, L60 (Leu 22) by Immunohistochemistry
CD43 IHC
Methodology:
CPT Code(s):
88342
2003571
Methodology:
Page | 141
CD44 IHC
CPT Code(s):
88342
2003574
CD45 IHC
Methodology:
CPT Code(s):
88342
2003586
CD52 (CAMPATH-1) by Immunohistochemistry
CD52 IHC
Methodology:
details, please contact ARUP Client Services
CPT Code(s):
88342
2003589
CD56 (NCAM) by Immunohistochemistry
CD56 IHC
Methodology:
CPT Code(s):
88342
2003592
CD57 IHC
Methodology:
CPT Code(s):
88342
2003595
CD61 (Platelet Gycoprotein IIIA) by Immunohistochemistry
Methodology:
Page | 142
CD61 IHC
CPT Code(s):
88342
2003598
CD68, KP1 by Immunohistochemistry
CD68 IHC
Methodology:
CPT Code(s):
88342
2003800
CD79A by Immunohistochemistry
CD79A IHC
Methodology:
CPT Code(s):
88342
2003806
CD117 (c-Kit) by Immunohistochemistry
CD117 IHC
Methodology:
CPT Code(s):
88342
2003809
CD123 IHC
Methodology:
CPT Code(s):
88342
2003812
CD138 (Syndecan-1) by Immunohistochemistry
Methodology:
Page | 143
CD138 IHC
CPT Code(s):
88342
2003815
CD163 IHC
Methodology:
CPT Code(s):
88342
2005534
CDK4 by Immunohistochemistry
CDK4 IHC
Methodology:
CPT Code(s):
88342
2004927
CDKL5-Related Disorders (CDKL5) Deletion/Duplication
CDKL5 DD
Methodology:
CPT Code(s):
83891 Isolation; 83896 x21 Nucleic acid probes; 83898 x21 Amplification; 83914 x21 Extension; 83909 Capillary electrophoresis; 83912
2004931
CDKL5-Related Disorders (CDKL5) Sequencing
CDKL5 FGS
Methodology:
CPT Code(s):
83891 Isolation; 83898 x26 Amplification; 83904 x26 Sequencing; 83909 Capillary electrophoresis; 83912 Interpretation and report - Additional
2004935
CDKL5-Related Disorders (CDKL5) Sequencing and Deletion/Duplication
CDKL5 FGA
Methodology:
Polymerase Chain Reaction/Sequencing/Multiplex Ligation-dependent Probe Amplification
CPT Code(s):
Sequencing: 83891 Isolation; 83898 x26 Amplification; 83904 x26 Sequencing; 83909 Capillary electrophoresis; 83912 Interpretation and report.
DelDup: 83896 x21 Nucleic Acid Probes; 83898 x21 Amplification; 83914 x21 Extension; 83909 Capillary Electrophoresis - Additional CPT
2003821
CDX2 by Immunohistochemistry
CDX2 IHC
Methodology:
Page | 144
CPT Code(s):
88342
2004247
CEBPA Mutation Detection
CEBPA MUT
Methodology:
Specimen Required: Collect: Lavender (EDTA) OR bone marrow (EDTA).
Specimen Preparation: Transport 5 mL whole blood (Min: 1 mL) OR 3 mL bone marrow (Min: 1 mL).
CPT Code(s):
83891 Isolation; 83898 x2 Amplification; 83894 Gel separation; 83904 x2 Sequencing, 83912 Interpretation and report - Additional CPT code
0051689
Celiac Disease Dual Antigen Screen
Methodology:
Unacceptable Conditions: Plasma or other body fluids. Contaminated, heat-inactivated, hemolyzed, icteric, or lipemic specimens.
CPT Code(s):
83516
TTG DGP
2002026
Celiac Disease Dual Antigen Screen with Reflex
CELIAC SCRN
Methodology:
Tube. (Min: 1 mL)
Unacceptable Conditions: Plasma. Contaminated, hemolyzed, or grossly lipemic specimens.
CPT Code(s):
83516 Dual antigen screen. If Dual antigen screen is 20 Units or greater, add 83516 tTG IgA and 83516 Gliadin IgA. If tTG IgA and Gliadin IgA
are negative, add 83516 tTG IgG and 83516 Gliadin IgG.
2005018
Celiac Disease (HLA-DQA1*05, HLA-DQB1*02, and HLA-DQB1*03:02) Genotyping
HLA CELIAC
Methodology:
CPT Code(s):
83891 Isolation; 83898 Amplification; 83900 Multiplex amplification; 83912 Interpretation and report - Additional CPT code modifiers may be
0051065
Celiac Disease Reflexive Panel
CELIAC TTG
Methodology:
Quantitative Nephelometry/Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Tube. (Min: 0.5 mL)
Remarks: Specify age of patient on test request form.
Unacceptable Conditions: Plasma. Contaminated, hemolyzed, or grossly lipemic specimens.
CPT Code(s):
82784 IgA; if less than 7 mg/dL, add 83516 tTG IgG and 83516 Gliadin IgG. If IgA is greater than or equal to 7 mg/dL, add 83516 tTG IgA and
83516 Gliadin IgA
0095019
Cell Count, Body Fluid
FLD
Methodology:
Cell Count/Differential
Specimen Required: Collect: Body fluid in liquid EDTA or sodium heparin.
Specimen Preparation: Do not freeze. Transport 3 mL body fluid. (Min: 0.5 mL)
Unacceptable Conditions: BAL fluid, gastric fluid, or seminal fluid. Synovial fluids collected in powdered EDTA or powdered lithium heparin.
Specimens sent with needle. Frozen specimens. Clotted specimens.
Stability: Ambient: 4 hours; Refrigerated: Crystal Analysis: 12 hours, All Others: 24 hours; Frozen: Unacceptable
CPT Code(s):
89051
Page | 145
0095018
Cell Count, CSF
Methodology:
Cell Count/Differential
Specimen Preparation: Do not freeze. Transport 0.5 mL CSF.
CPT Code(s):
89051
0051273
Cell-Mediated Immune Function Screen
Methodology:
Cell Culture/Quantitative Chemiluminescent Immunoassay
Specimen Required: Collect: Green (sodium heparin). Specimen must be collected within 30 hours of test performance.
Specimen Preparation: Transport 3 mL whole blood in original collection tube. (Min: 0.5 mL) LIVE LYMPHOCYTES REQUIRED.
Storage/Transport Temperature: CRITICAL ROOM TEMPERATURE. Do not refrigerate or freeze.
Unacceptable Conditions: Refrigerated or frozen specimens. Specimens older than 30 hours.
CPT Code(s):
86352
CSF
LMPS
0050714
Centromere Antibody, IgG
ANTICENT
Methodology:
Semi-Quantitative Multiplex Bead Assay
Unacceptable Conditions: Plasma. Contaminated, hemolyzed, or severely lipemic specimens.
CPT Code(s):
83516
2003172
Cerebral Cavernous Malformation (CCM1, CCM2 and CCM3) Deletion/Duplication
CCM DELDUP
Methodology:
CPT Code(s):
83891 Isolation; 83896 x2 Nucleic Acid Probes; 83898 x2 Amplification; 83914 x2 Extension; 83909 x2 Capillary Electrophoresis; 83912
2003152
Cerebral Cavernous Malformation (CCM1) Sequencing
CCM1 FGS
Methodology:
CPT Code(s):
83891 Isolation; 83898 x16 Amplification; 83904 x16 Sequencing; 83909 Capillary electrophoresis, 83912 Interpretation and report - Additional
2003164
Cerebral Cavernous Malformation (CCM1) Sequencing with Reflex to (CCM1, CCM2 and CCM3)
CCM COMP
Deletion/Duplication with Reflex to (CCM2) Sequencing with Reflex to (CCM3) Sequencing
Methodology:
CPT Code(s):
CCM1 Sequencing: 83891 Isolation; 83898 x16 Amplification; 83904 x16 Sequencing; 83909 Capillary electrophoresis; 83912 Interpretation
and report.
If reflexed to Del/Dup: 83896 x2 Nucleic Acid Probes; 83898 x2 Amplification; 83914 x2 Extension; 83909 x2 Capillary electrophoresis. If
reflexed to CCM2 Sequencing, add 83898 x10 Amplification; 83904 x10 Sequencing; 83909 Capillary electrophoresis. If reflexed to CCM3
Sequencing, add 83898 x7 Amplification; 83904 x7 Sequencing; 83909 Capillary electrophoresis. - Additional CPT code modifiers may be
2003156
CCM2 FGS
Methodology:
CPT Code(s):
2003160
CCM3 FGS
Methodology:
CPT Code(s):
Page | 146
0060106
Cerebrospinal Fluid (CSF) Culture and Gram Stain
MC CSF
Methodology:
Specimen Preparation: Do not refrigerate for bacterial culture. Transfer 1 mL CSF to a sterile container. Place each specimen in an individually
sealed bag.
CPT Code(s):
87070
0050160
Methodology:
Ceruloplasmin
CERU
Specimen Required: Collect: Serum separator tube or plasma preparation tube. Also acceptable: Plasma collected in green (lithium heparin).
collection. Transfer 0.5 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.2 mL)
Unacceptable Conditions: EDTA plasma or hemolyzed specimens.
Stability: After separation from cells: Ambient: 8 hours; Refrigerated: 72 hours; Frozen: 1 month
CPT Code(s):
82390
2006222
CHARGE Syndrome (CHD7) Sequencing
CHARGE FGS
Methodology:
Sequencing
CPT Code(s):
83891 Isolation; 83900 Amplification; 83901 x43 Additional amplification; 83894 x45 Gel separation; 83904 x90 Sequencing; 83892 x2
Digestion; 83912 Interpretation and report.
2002067
Chimerism, Donor
STR-DONOR
Methodology:
Polymerase Chain Reaction/Fragment Analysis
Specimen Required: Collect: Lavender (EDTA), pink (K2EDTA), or yellow (ACD Solution A or B). OR bone marrow in lavender (EDTA). OR buccal brushes from
donor.
Specimen Preparation: Transport 3 mL whole blood (Min: 1 mL) OR 1 mL bone marrow OR 2 buccal brushes in a sterile, dry tube.
Remarks: Post-transplantation results will be compared to pre-transplant recipient and donor genotypes, therefore, donor and recipient
samples must be obtained and genotyped before the transplant event occurs.
CPT Code(s):
83891 Isolation; 83900 Multiplex amplification; 83901 x14 Multiplex amplification; 83909 Capillary Electrophoresis; 83912 Interpretation and
2002066
Chimerism, Post-Transplant
STR-POST
Methodology:
Specimen Required: Collect: Lavender (EDTA), pink (K2EDTA), or yellow (ACD Solution A or B). OR bone marrow in lavender (EDTA).
Specimen Preparation: Transport 3 mL whole blood OR 1 mL bone marrow.
specimens must be obtained and genotyped before the transplant event occurs.
If cell sorting is required, refer to Chimerism, Post-Transplant, Sorted Cells (ARUP test code 2002064).
CPT Code(s):
83891 Isolation; 83900 Multiplex amplification; 83901 x14 Multiplex amplification; 83909 Capillary electrophoresis; 83912 Interpretation and
2002064
Chimerism, Post-Transplant, Sorted Cells
STR-POSTSC
Methodology:
Specimen Required: Collect: Lavender (EDTA), pink (K2EDTA), or yellow (ACD Solution A or B). OR bone marrow.
Specimen Preparation: Transport 3 mL whole blood. (Min: 3 mL) OR 1 mL bone marrow. Ship overnight. If cell sorting is required, specimens
should be received within 24 hours of collection for optimal isolation of the requested cell line(s). Increase the amount of blood/bone marrow
submitted based on the number of cell lines requested and for patients with low cell counts.
Storage/Transport Temperature: Ambient.
Remarks: Post-transplantation genotypes will be compared to pre-transplant recipient and donor genotypes. Therefore, donor and
recipient specimens must be obtained and genotyped before the transplant event occurs. Please provide the results and date of the patient's
most recent WBC and differential counts. When submitting bone marrow specimens for cell sorting, please provide information regarding the
general cellularity of the patient's bone marrow. See Cell Isolation Request for Chimerism, Post-Transplant, Sorted Cells.
Unacceptable Conditions: Frozen specimens. Clotted or hemolyzed specimens.
CPT Code(s):
83891 Isolation; 83900 Multiplex amplification; 83901 x14 Additional amplification; 83909 Capillary electrophoresis; 83912 Interpretation and
2002065
Chimerism, Recipient Pre-Transplant
STR-PRE
Methodology:
Specimen Required: Collect: Lavender (EDTA), pink (K2EDTA), or yellow (ACD Solution A or B). OR bone marrow in lavender (EDTA). OR buccal brushes from
recipient.
Specimen Preparation: Transport 3 mL whole blood (Min: 1 mL) OR 1 mL bone marrow OR 2 buccal brushes in a sterile, dry tube.
Page | 147
CPT Code(s):
specimens must be obtained and genotyped before the transplant event occurs.
83891 Isolation; 83900 Multiplex amplification; 83901 x14 Additional amplification; 83909 Capillary Electrophoresis; 83912 Interpretation and
0065100
Chlamydia Antibody Panel, IgG & IgM by IFA
V CHLM PAN
Methodology:
Unacceptable Conditions: Contaminated, hemolyzed, or hyperlipemic sera.
CPT Code(s):
86631 C. trachomatis IgG; 86631 C. pneumoniae IgG; 86631 C. psittaci IgG; 86632 C. trachomatis IgM; 86632 C. pneumoniae IgM; 86632 C.
psittaci IgM
0065139
Chlamydia Antibody Panel, IgG by IFA
CHLAM G
Methodology:
Specimen Preparation: Separate serum from cells ASAP or within 2 hours of collection. Transfer1 mL serum to an ARUP Standard Transport
CPT Code(s):
86631 C. trachomatis IgG; 86631 C. pneumoniae IgG; 86631 C. psittaci
0065105
Chlamydia Antibody Panel, IgM by IFA
V CHLAM M
Methodology:
CPT Code(s):
86632 C. trachomatis IgM; 86632 C. pneumoniae IgM; 86632 C. psittaci IgM
0060715
Chlamydia pneumoniae by PCR
CPNEUMOPCR
Methodology:
Specimen Required: Collect: Respiratory specimen: Bronchoalveolar lavage (BAL), nasal wash, nasopharyngeal swab, or pleural fluid.
Specimen Preparation: Fluid: Transfer 2 mL respiratory specimen to a sterile container. (Min: 0.5 mL) Also acceptable: Transfer to viral transport
media (ARUP supply #12884). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787.
Place each specimen in a separate, individually sealed bag. Swabs: Place in viral transport media
Stability: Ambient: 24 hours; Refrigerated: 14 days; Frozen: 1 month.
CPT Code(s):
87486
0060241
Chlamydia trachomatis and Neisseria gonorrhoeae by Amplified Detection (APTIMA®)
CGAMD
Methodology:
Qualitative Target Amplification Nucleic Acid Probe
Specimen Required: Collect: Endocervical or vaginal swab, first catch urine, or male urethral swabs. Collect in APTIMA® Combo 2 Assay transport media (ARUP
Supply: Swabs #28907, Urine #28908). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 5222787. Refer to "Sample Collection for the Diagnosis of STD" under Specimen Handling at www.aruplab.com for specific specimen collection and
transport instructions.
Specimen Preparation: Transfer swab or urine to APTIMA® Combo 2 Assay transport media. (Min: 2 mL urine)
Remarks: Specimen source is required.
Unacceptable Conditions: Large white swab is for preparatory cleaning of the endocervix and is unacceptable for testing. Specimens in any
transport media other than indicated above. Specimen in swab transport media without a swab.
Stability: Unpreserved Urine: Ambient: 24 hours; Refrigerated: 24 hours; Frozen: Unacceptable. APTIMA® Transport Media: Swab:
Ambient: 2 months; Refrigerated: 2 months; Frozen: 12 months Urine: Ambient: 1 month; Refrigerated: 1 month; Frozen: 12 months
CPT Code(s):
87491 Chlamydia trachomatis, 87591 Neisseria gonorrhoeae
0060774
Chlamydia trachomatis and Neisseria gonorrhoeae by Amplified Detection (APTIMA®), M4/UTM Specimens
CTNG M4
Methodology:
Specimen Required: Collect: Endocervical or urethral swab in viral transport media (M4) or UTM (ARUP supply #12884). Available online through eSupply using
ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. Refer to "Sample Collection for the Diagnosis of STD" under Specimen
Handling at www.aruplab.comwww.aruplab.com for specific specimen collection and transport instructions.
Specimen Preparation: Transport swab in 3 mL viral transport media (M4 or UTM). (Min: 1 mL)
Stability: Ambient: 1 week; Refrigerated: 1 month; Frozen: 3 months
CPT Code(s):
Page | 148
2001551
Chlamydia trachomatis and Neisseria gonorrhoeae by Amplified Detection (APTIMA®) on SurePath™
CTNG SP
Methodology:
Specimen Required: Collect: Cervical brush in SurePath™ liquid-based Pap test Media. Refer to "Sample Collection for the Diagnosis of STD" under Specimen
Handling at www.aruplab.com for specific specimen collection and transport instructions.
Specimen Preparation: Vortex SurePath™ media and transfer a 1 mL aliquot to APTIMA® Combo 2 transport media (ARUP supply #42711)
within 24 hours of collection. Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. To
reduce the potential for contamination SurePath® specimens should be poured off, using sterile technique, into the APTIMA® Specimen Transfer
Tube prior to Cytology Testing.
Stability: SurePath™ Media: Ambient: 24 hours; Refrigerated: 48 hours; Frozen: 1 week
APTIMA® Media: Ambient: 2 weeks; Refrigerated: 1 month; Frozen: 1 month
CPT Code(s):
0060734
Chlamydia trachomatis and Neisseria gonorrhoeae by Amplified Detection (APTIMA®) on ThinPrep™
CG MATP
Methodology:
Specimen Required: Collect: Cervical brush in ThinPrep® transport Pap Test™ Media. Refer to "Sample Collection for the Diagnosis of STD" under Specimen
Handling at www.aruplab.com for specific specimen collection and transport instructions.
Specimen Preparation: Vortex Pap Test™ media and transfer a 1 mL aliquot to APTIMA® Combo 2 transport media (ARUP supply #42711).
Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. To reduce the potential for
contamination, ThinPrep® specimens should be poured off, using sterile technique, into the APTIMA® Specimen Transfer Tube prior to
Cytology Testing.
Stability: Specimen in ThinPrep® media: Ambient: 1 month; Refrigerated: 1 month; Frozen: Unacceptable
Specimen in APTIMA® transport media: Ambient: 2 weeks; Refrigerated: 1 month; Frozen: 12 months
CPT Code(s):
0060224
Methodology:
Chlamydia trachomatis and Neisseria gonorrhoeae DNA Probe
GCCHP
Qualitative Nucleic Acid Probe
For urethral swab specimens, patients should not have urinated for at least 1 hour prior to collection.
Specimen Required: Collect: Endocervical or male urethral swabs. Collect in Gen-ProbePace 2 collection and transport kit (ARUP Supply: Female kit: #12575, Male
kit: #12576). Available online through eSupply using ARUP Connector contact ARUP Client Services at (800) 522-2787.
Specimen Preparation: Transport swab in Gen-Probe® Pace 2 transport media.
Unacceptable Conditions: Specimens in any transport media other than indicated above. Specimen in swab transport media without a swab. Gross
presence of blood in the specimen.
Stability: Ambient: 1 week; Refrigerated: 1 week; Frozen: 1 month
CPT Code(s):
87800
0060243
Chlamydia trachomatis by Amplified Detection (APTIMA®)
CTAMD
Methodology:
Specimen Required: Collect: Endocervical or vaginal swab, first catch urine, or male urethral swabs . Collect in APTIMA® Combo 2 Assay transport media (ARUP
supply: Swabs #28907, Urine #28908). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 5222787. Refer to Sample Collection for the Diagnosis of STD under Specimen Handling at www.aruplab.com for specific specimen collection and
transport instructions.
Specimen Preparation: Transfer swab or urine to APTIMA® Combo 2 Assay transport media. (Min: 2 mL urine)
Unacceptable Conditions: Large white swab is for preparatory cleaning of the endocervix and is unacceptable for testing. Specimens in any
transport media other than indicated above. Specimen in swab transport media without a swab.
Stability: Unpreserved Urine: Ambient: 24 hours; Refrigerated: 24 hours; Frozen: Unacceptable. APTIMA®Transport Media: Swab:
Ambient: 2 months; Refrigerated: 2 months; Frozen: 12 months Urine: Ambient: 1 month; Refrigerated: 1 month; Frozen: 12 months
CPT Code(s):
87491
0060850
Chlamydia trachomatis Culture
CHLAM
Methodology:
Cell Culture/Immunofluorescence
Specimen Required: Collect: Cervical, eye, rectal, urethral swab, or peritoneal fluid. Also acceptable for newborns: Nasopharyngeal aspirate, swab or washing.
Specimen Preparation: Transfer specimen immediately to Chlamydia transport media (UTM) (ARUP supply #12884). Available online through
eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. Place each specimen in an individually sealed bag. Also
acceptable: Any transport media validated for Chlamydia transport.
Storage/Transport Temperature: Frozen on dry ice.
Unacceptable Conditions: Urine. Specimens not preserved in Chlamydia culture transport media. Calcium alginate, dry, or wood swabs.
Stability: Ambient: 1 hour; Refrigerated: 48 hours; Frozen at -70°C: 1 month
CPT Code(s):
87110 Culture; 87140 Stain
0060287
Chlamydia trachomatis DFA
CHLAF
Methodology:
Direct Fluorescent Antibody Stain
Specimen Required: Collect: Eye, genital, nasopharyngeal, or rectal swab.
For Chlamydia DFA only, collection kits with fixative are available (ARUP supply #16578). Available online through eSupply using ARUP
Specimen Preparation: Fix slide as directed by collection kit. Transport fixed slide.
Unacceptable Conditions: Swabs in gel. Transport systems designed for use with other methodologies of Chlamydia testing. Dry swabs.
Page | 149
CPT Code(s):
Stability: Fixed Slide: Ambient: 1 week; Refrigerated: 1 week; Frozen: 1 week
87270
0065059
Methodology:
Chlamydia trachomatis DNA Probe
CHLDNAP
Qualitative Nucleic Acid Probe
For urethral swab specimens, patients should not have urinated for at least 1 hour prior to collection.
Specimen Required: Collect: Conjunctival, endocervical or male urethral swabs. Collect in Gen-Probe® Pace 2 collection and transport media (ARUP Supply: Female
kit: #12575, Male kit: #12576). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787.
Specimen Preparation: Transport swab in Gen-Probe® Pace 2 transport media.
Unacceptable Conditions: Specimen in swab transport media without a swab. Gross presence of blood in the specimen.
Stability: Ambient: 1 week; Refrigerated: 1 week; Frozen: 1 month.
CPT Code(s):
87490
0091267
Chloral Hydrate, Serum or Plasma
Methodology:
Gas Chromatography
Specimen Required: Collect: Plain red or gray (sodium fluoride/potassium oxalate).
CPT Code(s):
82491
TRICHLOROE
0090346
Chloramphenicol
CHLORAM
Methodology:
Specimen Preparation: Separate serum or plasma from cells within 2 hours of collection. Transport 1 mL serum or plasma to an ARUP Standard
Stability: After separation from cells: Ambient: 48 hours; Refrigerated: 3 weeks; Frozen: 3 weeks
CPT Code(s):
82415
0020381
Chloride, Fecal
FE-CL
Methodology:
Quantitative Ion-Selective Electrode
Specimen Required: Collect: Liquid random stool.
Specimen Preparation: Transfer 5 g aliquot of liquid random stool to an unpreserved stool transport vial (ARUP Supply #40910). (Min: 1 g) Do
not add saline or water to liquefy specimen.
Unacceptable Conditions: Formed or viscous stool.
Stability: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 1 month
CPT Code(s):
82438
0020163
Chloride, Fluid
CL FL
Methodology:
Specimen Preparation: Centrifuge to remove cellular material. Transfer 1 mL body fluid to an ARUP Standard Transport Tube. (Min: 0.2 mL)
Unacceptable Conditions: Breast milk and salivary fluid. Specimens containing sodium fluoride/potassium oxalate as anticoagulants.
Contaminated or hemolyzed specimens. Specimens too viscous to be aspirated by instrument.
CPT Code(s):
82438
0020003
Chloride, Serum or Plasma
CL
Methodology:
Unacceptable Conditions: Body Fluid (refer to Chloride, Fluid, ARUP test code 0020163). Urine (refer to Chloride, Urine, ARUP test code
0020850). Specimens containing sodium fluoride/potassium oxalate as anticoagulants. Hemolyzed specimens.
CPT Code(s):
82435
0020850
Methodology:
Chloride, Urine
U CL
UUHC Clients: Titration
All other clients: Quantitative Ion-Selective Electrode
Specimen Required: Collect: 24-hour urine (without additives). Refrigerate during collection. Also acceptable: Random urine.
Specimen Preparation: Transfer 1 mL aliquot of urine from a well-mixed collection to an ARUP Standard Transport Tube. (Min: 0.5 mL) Record
total volume and collection time interval on transport tube and test request form.
CPT Code(s):
82436
0091310
Chloroquine, Plasma
Methodology:
Page | 150
CHLOROQUI
CPT Code(s):
Specimen Preparation: Separate plasma from cells within 2 hours of draw. Transfer 1 mL plasma to an ARUP Standard Transport Tube. (Min: 0.4
mL)
82101
0090870
Chlorpromazine
CHLORP
Methodology:
Transport Tube. (Min: 1 mL)
SST or PST: Separate serum or plasma from gel within 6 hours and hold at room temperature or separate within 2 hours and store refrigerated.
Unacceptable Conditions: Whole blood. Light blue (citrate) or yellow (SPS or ACD solution).
Stability: After separation from cells: Ambient: 12 hours; Refrigerated: 72 hours; Frozen: 5 days
CPT Code(s):
84022
0091216
Chlorpropamide, Serum or Plasma
Methodology:
CPT Code(s):
80299
0091494
Chlorpropamide, Urine
Methodology:
CPT Code(s):
80299
0020714
Cholesterol, Fluid
Methodology:
Specimen Preparation: Transport 1 mL body fluid. (Min: 0.5 mL)
CPT Code(s):
84311
CHLORPRO S
CHLORPR U
CHOL FL
0020031
Cholesterol, Serum or Plasma
CHOL
Methodology:
Unacceptable Conditions: Body Fluid (refer to Cholesterol, Fluid, ARUP test code 0020714).
CPT Code(s):
82465
0020174
Cholinesterase, RBC/Hb Ratio
Methodology:
Specimen Preparation: DO NOT FREEZE. Transport 3 mL whole blood. (Min: 1 mL))
Storage/Transport Temperature: Refrigerated. Do not place whole blood directly on cool packs when shipping.
Unacceptable Conditions: Green (sodium or lithium heparin). Frozen specimens. Clotted or hemolyzed specimens.
CPT Code(s):
82482
CHE-RBC
0040203
Chorionic Villus, FISH
FISHCVS
Methodology:
Specimen Required: Collect: Thaw media prior to collection. Chorionic villus in a sterile, screw-top container filled with tissue culture transport medium (ARUP
Supply #32788). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787.
Specimen Preparation: DO NOT FREEZE. Do not place in formalin. Transport chorionic villus (CVS) specimen in a sterile, screw-top container
filled with tissue culture transport medium.
Cytogenetic (Chromosome) Studies with the electronic packing list (available at http://www.aruplab.com/genetics/forms.php).
Unacceptable Conditions: Frozen specimens. Specimens preserved in formalin.
CPT Code(s):
88271 x5 DNA probe; 88275 Chromosomal in situ hybridization, 100-300 cells; 88291 Interpretation and report
Page | 151
2005287
Chromatin Antibody, IgG
CHROMATIN
Methodology:
Unacceptable Conditions: Urine or plasma. Contaminated, heat-inactivated, severely hemolyzed, icteric, or lipemic specimens.
CPT Code(s):
83516
2005548
Methodology:
Chromium, Joint Fluid
CR F
High concentrations of iodine may interfere with elemental testing. Patients should abstain from iodine-containing
medications or contrast agents for at least 1 month prior to specimen collection for elemental testing.
Specimen Required: Collect: Joint fluid. The use of betadine-like topical antiseptics should be avoided during specimen collection.
Specimen Preparation: Transfer 1 mL joint fluid to an ARUP Trace Element-Free Transport Tube (ARUP supply #43116). Available online
through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 0.5 mL)
Unacceptable Conditions: Separator tubes or gels. Fluid collected after administration of a gadolinium (Gd) containing contrast media (may occur
with MRI studies).
CPT Code(s):
82495
0098830
Methodology:
Chromium, Serum
CR S
Specimen Required: Collect: Royal blue (no additive).
Specimen Preparation: Centrifuge; do not allow serum to remain on cells. Transfer 2 mL serum to an ARUP Trace Element-Free Transport Tube
(ARUP supply #43116). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 0.5
mL)
Unacceptable Conditions: Separator tubes. Specimens that are not separated from the red cells or clot within 6 hours.
CPT Code(s):
82495
0025068
Methodology:
Chromium, Urine
CR-U
CPT Code(s):
82495
0080469
Chromogranin A
CGA SERUM
Methodology:
Specimen Preparation: Allow serum specimen to clot completely at room temperature. Transfer 1 mL serum to an ARUP Standard Transport
Tube. (Min: 0.5 mL)
Unacceptable Conditions: Plasma. Icteric or lipemic specimens.
Stability: After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 6 weeks
CPT Code(s):
86316
2003830
Chromogranin A by Immunohistochemistry
CHROMO IHC
Methodology:
CPT Code(s):
88342
Page | 152
2005749
Methodology:
Chromosome Analysis - Breakage, Ataxia Telangiectasia, Whole Blood
BREAKAGEAT
Giemsa Band
Specimens must be collected and shipped Monday-Thursday only and not the day before a holiday.
Specimen Preparation: Transport 10 mL whole blood. (Min: 5 mL) Specimens must be received within 48 hours to insure adequate culture of
living cells.
CPT Code(s):
88230 Tissue culture, non-neoplastic; 88248 Baseline breakage
0097688
Methodology:
Chromosome Analysis - Breakage, Fanconi Anemia
BREAKAGE
Giemsa Band
Specimens must be collected and shipped Monday-Thursday only and not the day before a holiday.
Specimen Preparation: Transport 10 mL whole blood. (Min: 5 mL) Specimens must be received within 48 hours to insure adequate culture of
living cells.
CPT Code(s):
88230 x2 Tissue culture, nonneoplastic; 88248 Baseline breakage; 88249 Score 100 clastogens stress; 88280 Additional karyotypes; 88291
Interpretation and report
2002293
Chromosome Analysis, Amniotic Fluid
CHR AF
Methodology:
Giemsa Band
Specimen Preparation: Do not freeze or expose to extreme temperatures. Transport 30 mL amniotic fluid in sterile centrifuge tubes. (Min: 15
mL) Specimen and completed test request form, including clinical indication, must be received within 48 hours of collection.
Prenatal Cytogenetics form (available at http://www.aruplab.com/genetics/forms.php).
Unacceptable Conditions: Frozen specimens. Bloody specimens.
CPT Code(s):
88269 Chromosome analysis in situ; 88235 Tissue culture; 88280 Additional karyotypes; 88291 Interpretation and report - Additional CPT code
2002292
Chromosome Analysis, Bone Marrow
CHR BM
Methodology:
Giemsa Band
Specimen Required: Collect: Non-diluted bone marrow aspirate. Collect in a heparinized syringe.
Specimen Preparation: Do not freeze or expose to extreme temperatures. Transfer 3 mL bone marrow to a green (sodium heparin). (Min: 0.5
mL)
Remarks: Although bone marrow is the recommended specimen type for hematological disorder studies, blood can be substituted if bone marrow
cannot be obtained. Refer to Chromosome Analysis, Leukemic Blood (ARUP test code 2002290). This test must be ordered using Cytogenetic test
request form #43099 or through your ARUP interface.
CPT Code(s):
88237 Tissue culture; 88264 Analyze 20-25 cells; 88291 Interpretation and report - Additional CPT code modifiers may be required for
procedures performed to test for oncologic or inherited disorders.
2007130
Chromosome Analysis, Bone Marrow with Reflex to Genomic Microarray
BM REFLEX
Methodology:
Giemsa Band/Genomic Microarray (Oligo-SNP array)
Specimen Required: Collect: Non-diluted bone marrow aspirate. Collect in a heparinized syringe
Specimen Preparation: Do not freeze or expose to extreme temperatures. Transfer 3 mL bone marrow to a green (sodium heparin). (Min: 0.5
mL)
Submit specimen according to Biological Substance, Category B, shipping guidelines.
Remarks: Although bone marrow is the recommended specimen type for hematological disorder studies, blood can be substituted if bone marrow
cannot be obtained. Refer to Chromosome Analysis, Leukemic Blood with Reflex to Genomic Microarray (ARUP test code 2007131). This test
must be ordered using Cytogenetic test request form (#43099) or through your ARUP interface. Submit the Patient History for Cytogenetic
(Chromosome) Studies with the electronic packing list (available at http://www.aruplab.com/genetics/forms.php).
Unacceptable Conditions: Frozen specimens. Clotted specimens
CPT Code(s):
88237 Tissue culture; 88264 Analyze 20-25 cells; 88291 Interpretation and report, if reflexed, add 83891 Isolation; 88386 x6 Array-based
evaluation of multiple molecular probes, 251-500. Additional CPT code modifiers may be required for procedures performed to test for oncologic
or inherited disorders.
2002291
Chromosome Analysis, Chorionic Villus
CHR CVS
Methodology:
Giemsa Band
Specimen Required: Collect: Thaw media prior to collection. Chorionic villus in a sterile, screw-top container filled with tissue culture transport medium (ARUP
Supply #32788). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. If cytogenetics
tissue media is not available, collect in plain RPMI, Hanks solution, saline, or ringers.
Specimen Preparation: DO NOT FREEZE. Do not place in formalin. Transport chorionic villus (CVS) specimen in a sterile, screw-top container
filled with tissue culture transport medium. If specimen size is too large for a normal collection tube, a larger sterile container can be used such as
a sterile urine cup and can be flooded with several tubes of cytogenetic tissue media.
Page | 153
CPT Code(s):
Prenatal Cytogenetics form with the electronic packing list (available at http://www.aruplab.com/genetics/forms.php).
88269 Chromosome analysis in situ; 88235 Tissue culture; 88280 Additional karyotype; 88291 Interpretation and report - Additional CPT code
2002290
Chromosome Analysis, Leukemic Blood
CHR LKB
Methodology:
Giemsa Band
Remarks: This test must be ordered using Cytogenetic test request form (#43099) or through your ARUP interface.
CPT Code(s):
2007131
Chromosome Analysis, Leukemic Blood with Reflex to Genomic Microarray
LKB REFLEX
Methodology:
Giemsa Band/Genomic Microarray (Oligo-SNP array)
Specimen Preparation: Do not freeze or expose to extreme temperatures. Transfer 5mL whole blood to a green (sodium heparin). (Min: 1.0
mL)
Submit specimen according to Biological Substance, Category B, shipping guidelines.
Cytogenetic (Chromosome) Studies form with the electronic packing list (available at http://www.aruplab.com/genetics/forms.php).
Unacceptable Conditions: Frozen specimens. Clotted specimens
CPT Code(s):
88237 Tissue culture; 88264 Analyze 20-25 cells; 88291 Interpretation and report, if reflexed, add 83891 Isolation; 88386 x6 Array-based
evaluation of multiple molecular probes, 251-500. Additional CPT code modifiers may be required for procedures performed to test for oncologic
or inherited disorders.
2002300
Chromosome Analysis, Lymph Node
CHR ONC
Methodology:
Giemsa Band
Specimen Required: Collect: Any specimen type for oncology studies other than peripheral blood, bone marrow, and solid tumors.
Thaw media prior to tissue inoculation. Collect tissue in a sterile, screw-top container filled with tissue culture transport medium (ARUP Supply
#32788). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. If no transport media is
available, collect in plain RPMI, Hanks solution, saline, or ringers.
Collect pleural or other body fluids in a green (sodium heparin).
Contact ARUP Genetics Processing for other specimen types or information and specific collection and transportation instructions.
Specimen Preparation: DO NOT FREEZE. Do not place in formalin.
Tissues: Transport 10 mm biopsy in a sterile, screw-top container filled with tissue culture transport media.
Fluid: Transport 5 mL fluid in original collection tube.
Remarks: This test must be ordered using Cytogenetic test request form #43099 or through your ARUP interface.
Unacceptable Conditions: Frozen specimens. Tissue submitted in formalin.
CPT Code(s):
2002289
Chromosome Analysis, Peripheral Blood
CHR PB
Methodology:
Giemsa Band
Remarks: This test must be ordered using Cytogenetic test request form #43097 or through your ARUP interface. Please submit the Patient
History for Cytogenetic (Chromosome) Studies form with the electronic packing list (available at http://www.aruplab.com/genetics/forms.php).
CPT Code(s):
88262 Chromosome analysis count 15-20 cells; 88230 Tissue culture; 88291 Interpretation and report - Additional CPT code modifiers may be
2005763
Chromosome Analysis, Peripheral Blood, with Reflex to Genomic Microarray
PB REFLEX
Methodology:
Giemsa Band/Genomic Microarray (Oligo-SNP Array)
Remarks: This test must be ordered using Cytogenetic test request form #43097 or through your ARUP interface. Please submit the Patient
History for Cytogenetic (Chromosome) Studies form with the electronic packing list (available at http://www.aruplab.com/genetics/forms.php).
CPT Code(s):
88262 Chromosome analysis count 15-20 cells; 88230 Tissue culture; 88291 Interpretation and report; if reflexed, add 83891 Isolation; 88386 x6
Array-based evaluation of multiple molecular probes, 251-500 - Additional CPT code modifiers may be required for procedures performed to test
for oncologic or inherited disorders.
Page | 154
2002288
Chromosome Analysis, Products of Conception
CHR POC
Methodology:
Giemsa Band
Specimen Required: Collect: Thaw media prior to tissue inoculation. Products of conception in a sterile, screw-top container (Wide mouth containers: ARUP supply
#42710) filled with tissue culture transport medium (ARUP Supply # 32788). Available online through eSupply using ARUP Connect™ or
contact ARUP Client Services at (800) 522-2787. If cytogenetics tissue media is not available, collect in plain RPMI, Hanks solution, saline, or
ringers.
If autopsy is performed: Chest wall cartilage (particularly if macerated), gonad, spleen, kidney, or other internal organs.
If no autopsy is performed: Placenta from fetal side is preferred (e.g. villi).
Also acceptable: Umbilical cord or achilles tendon.
Specimen Preparation: DO NOT FREEZE. Do not place in formalin. Transport products of conception in sterile, screw-top container filled with
tissue transport medium. If specimen size is too large for a normal collection tube, a larger sterile container can be used such as a sterile urine cup
and can be flooded with several tubes of cytogenetic tissue media.
Prenatal Cytogenetics with the electronic packing list (available at http://www.aruplab.com/genetics/forms.php).
Unacceptable Conditions: Intact fetus. Frozen specimens. Specimens preserved in formalin.
CPT Code(s):
88262 Chromosome analysis count 15-20 cells; 88233 Tissue culture; 88291 Interpretation and report - Additional CPT code modifiers may be
2005762
Chromosome Analysis, Products of Conception, with Reflex to Genomic Microarray
POC REFLEX
Methodology:
Giemsa Band/Genomic Microarray (Oligo-SNP Array)
Specimen Required: Collect: Thaw media prior to tissue inoculation. Products of conception in a sterile, screw-top container (Wide mouth containers: ARUP supply
#42710) filled with tissue culture transport medium (ARUP Supply # 32788). Available online through eSupply using ARUP Connect™ or
contact ARUP Client Services at (800) 522-2787. If cytogenetics tissue media is not available, collect in plain RPMI, Hanks solution, saline, or
ringers.
If autopsy is performed: Chest wall cartilage (particularly if macerated), gonad, spleen, kidney, or other internal organs.
If no autopsy is performed: Placenta from fetal side is preferred (e.g. villi).
Also acceptable: Umbilical cord or achilles tendon.
Specimen Preparation: DO NOT FREEZE. Do not place in formalin. Transport products of conception in sterile, screw-top container filled with
Prenatal Cytogenetics with the electronic packing list (available athttp://www.aruplab.com/genetics/forms.php).
Unacceptable Conditions: Frozen specimens. Intact fetus. Specimens preserved in formalin.
CPT Code(s):
88262 Chromosome analysis count 15-20 cells; 88233 Tissue culture; 88291 Interpretation and report; if reflexed, add 83891 Isolation; 88386 x6
Array-based evaluation of multiple molecular probes, 251-500 - Additional CPT code modifiers may be required for procedures performed to test
for oncologic or inherited disorders.
2002287
Chromosome Analysis, Rule Out Mosaicism
CHR R/OM
Methodology:
Giemsa Band
Cytogenetic (Chromosome) Studies with the electronic packing list (available at http://www.aruplab.com/guides/ug/tests/2002287.jsp).
CPT Code(s):
88230 Tissue culture; 88263 Chromosome analysis count 45 cells; 88280 Additional karyotypes; 88285 Chromosome analysis, additional cells
counted; 88291 Interpretation and report
0097677
Chromosome Analysis, Sister Chromatid Exchange
SCE
Methodology:
Giemsa Band
CPT Code(s):
88230 x2 Tissue culture; 88245 Chromosome analysis breakage syndrome, baseline SCE; 88262 Chromosome analysis count 15-20 cells; 88280
Additional karyotypes; 88291 Interpretation and report
2002286
Chromosome Analysis, Skin Biopsy
CHR SKIN
Methodology:
Giemsa Band
Specimen Required: Collect: Thaw media prior to tissue inoculation. Skin biopsy in a sterile, screw-top container filled with tissue culture transport medium (ARUP
Supply # 32788) Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. If cytogenetics
tissue media is not available, collect in plain RPMI, Hanks solution, saline, or ringers.
Specimen Preparation: DO NOT FREEZE. Do not place in formalin. Transport a 4 mm skin biopsy in a sterile, screw-top container filled with
Cytogenetic (Chromosome) Studies form with the electronic packing list (available at http://www.aruplab.com/genetics/forms.php).
CPT Code(s):
88262 Chromosome analysis count 15-20 cells; 88233 Tissue culture; 88291 Interpretation and report
Page | 155
2002296
Chromosome Analysis, Solid Tumor
CHR ST
Methodology:
Giemsa Band
Specimen Required: Collect: Thaw media prior to tissue inoculation. Solid tumor biopsy in a sterile, screw-top container filled with tissue culture transport medium
(ARUP Supply #32788). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. If
cytogenetics tissue media is not available, collect in plain RPMI, Hanks solution, saline, or ringers.
Specimen Preparation: DO NOT FREEZE. Do not place in formalin. Transport a 10 mm biopsy in a sterile, screw-top container filled with tissue
culture transport medium. (Min: 5 mm) If specimen size is too large for a normal collection tube, a larger sterile container can be used such as a
sterile urine cup and can be flooded with several tubes of cytogenetic tissue media.
CPT Code(s):
2002295
Chromosome FISH, CLL Panel
FISH CLLP
Methodology:
Specimen Required: Collect: Green (sodium heparin). Also acceptable: Non-diluted bone marrow aspirate collected in a heparinized syringe.
Specimen Preparation: Transport 5 mL whole blood (Min: 2 mL). OR Transfer 3 mL bone marrow to a green (sodium heparin) (Min: 1 mL)
Remarks: If cell pellets or dropped cytogenetic slides are submitted, processing fee will not apply.
Unacceptable Conditions: Frozen specimens. Paraffin-embedded specimens. Clotted specimens.
Stability: Ambient: 48 hours; Refrigerated: 48 hours; Frozen; Unacceptable.
CPT Code(s):
88271 x4 DNA probe; 88275 x4 Chromosomal in situ hybridization 100-300 cells; 88291 Interpretation and report - Additional CPT code
modifiers may be required for procedures performed to test for oncologic or inherited disorders
2002298
Chromosome FISH, Interphase
CHR FISHI
Methodology:
Specimen Required: Collect: Non-diluted bone marrow aspirate collected in a heparinized syringe. Also acceptable: Green (sodium heparin).
Specimen Preparation: Transfer 3 mL bone marrow to a green (sodium heparin) (Min: 1 mL). OR transport 5 mL whole blood (Min: 2 mL)
Remarks: If cell pellets or dropped cytogenetic slides are submitted, processing fee will not apply.
CPT Code(s):
88271 DNA probe each; 88275 Interphase in situ hybridization 100-300 each; 88291 Interpretation and report - Additional CPT codes modifiers
may be required for procedures performed to test for oncologic or inherited disorders
2002299
Chromosome FISH, Metaphase
CHR FISHM
Methodology:
Specimen Required: Collect: Green (sodium heparin). Also acceptable: Non-diluted bone marrow aspirate collected in a heparinized syringe.
Specimen Preparation: Transport 5 mL whole blood (Min: 2 mL). OR transfer 3 mL bone marrow to a green (sodium heparin) (Min: 1 mL).
Remarks: It is recommended that all FISH studies be done in conjunction with routine cytogenetic analysis. (Refer to appropriate Chromosome
Analysis test for order instructions). If FISH only is requested, please submit a copy of previous cytogenetics report.
If cell pellets or dropped cytogenetic slides are submitted, processing fee will not apply.
CPT Code(s):
88271 DNA probe each; 88273 Chromosomal in situ hybridization 10-30 cells each; 88291 Interpretation and report - Additional CPT code
2006270
Chromosome FISH, Multiple Myeloma Panel Process and Hold
Methodology:
Cell culture/Fluorescence in situ Hybridization
Specimen Required: Collect: Non-diluted bone marrow collected in a heparinized syringe. Also acceptable: Green (sodium heparin).
Specimen Preparation: Transfer 3 mL bone marrow to a green (sodium heparin). (Min: 1 mL)
CPT Code(s):
88237
MMF PR &HLD
2002297
Chromosome FISH, Prenatal
CHR FISHP
Methodology:
Specimen Preparation: Do not freeze or expose to extreme temperatures. Transport 30 mL amniotic fluid in sterile centrifuge tubes. (Min: 15
mL)
Remarks: Specimen and completed test request form, including clinical indication, must be received within 48 hours of collection.
It is recommended that FISH be performed in conjunction with routine cytogenetic analysis.
Page | 156
CPT Code(s):
(Chromosome) Studies form with the electronic packing list (available at available at http://www.aruplab.com/genetics/forms.php).
Unacceptable Conditions: Frozen specimens. Bloody specimens.
88271 x5 DNA probe; 88275 Interphase in situ hybridization 100-300; 88291 Interpretation and report - Additional CPT code modifiers may be
2006356
Chronic Granulomatous Disease (CYBB Gene Scanning and NCF1 Exon 2 GT Deletion) with Reflex to CYBB
CGD PANEL
Sequencing
Methodology:
High Resolution Melt Analysis
Unacceptable Conditions: Frozen
CPT Code(s):
83891 Isolation; 83898 Amplification; 83896 Nucleic acid probe; 83900 Multiplex Amplification; 83901 x14 Additional Amplification; 83903
x16 Mutation Scanning; 83912 Interpretation and report. If reflexed, add 83904 Sequencing, each segment. Additional CPT code modifiers may
2006366
Chronic Granulomatous Disease (NCF1) Exon 2 GT Deletion
NCF1
Methodology:
CPT Code(s):
83891 Isolation; 83898 Amplification; 83896 Nucleic acid probe; 83912 Interpretation and report. Additional CPT code modifiers may be
2006361
Chronic Granulomatous Disease, X-Linked (CYBB) Gene Scanning with Reflex to Sequencing
CYBB
Methodology:
CPT Code(s):
83891 Isolation; 83900 Multiplex Amplification; 83901 x14 Additional Amplification; 83903 x16 Mutation Scanning; 83912 Interpretation and
report. If reflexed, add 83904 Sequencing, each segment. Additional CPT code modifiers may be required for procedures performed to test for
oncologic or inherited disorders.
0093194
Chronic Lymphocytic Leukemia Follow up Phenotyping by Flow Cytometry
CLL FLOW
Methodology:
Flow Cytometry
Specimen Required: Collect: Green (sodium heparin), lavender (EDTA), or pink (K2EDTA).
Specimen Preparation: Transport 5 mL whole blood.
Storage/Transport Temperature: Room temperature. Specimen should be received within 24 hours of collection for optimal viable testing.
Remarks: This assay is for follow up after the diagnosis of CLL has been established by previous flow cytometry immunophenotyping. If prior
studies were not performed at ARUP, the outside flow cytometry report and histograms must accompany the specimen. In addition, please provide
CBC, Wright's stained smear, clinical history, and any relevant pathology reports.
Unacceptable Conditions: Frozen specimens. Specimens greater than 48 hours old. Clotted or hemolyzed specimens.
CPT Code(s):
88184 First marker, 88185 x7 Each additional marker, 88187 Interpretation
0098457
Chylomicron Screen, Body Fluid
Methodology:
Qualitative Electrophoresis
Specimen Preparation: Do not freeze. Transport 1 mL body fluid. (Min: 0.2 mL
Remarks: Specify type of body fluid.
Unacceptable Conditions: Plasma, serum, or whole blood. Frozen specimens.
Stability: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: Unacceptable
CPT Code(s):
82664
CHYLO FL
2005160
Methodology:
Chymotrypsin, Fecal
CHYMOTRYP
Quantitative Enzymatic/Spectrophotometry
Patients receiving pancreatic enzymes should discontinue taking the enzymes at least 5 days prior to stool collection.
Specimen Required: Collect: Random stool.
Specimen Preparation: Transfer 1 g stool to a clean, unpreserved stool transport vial (ARUP Supply #40910). (Min: 0.5 g)
CPT Code(s):
84311
0091337
Cimetidine, Serum or Plasma
Methodology:
CPT Code(s):
80299
Page | 157
CIMETIDINE
0091422
Cimetidine, Urine
Methodology:
CPT Code(s):
80299
CIMETID U
0093399
Methodology:
Circulating Tumor Cell Count (Cell Search™)
CTC COUNT
Immunomagnetic Separation/Immunofluorescent Stain/Computer Assisted Analysis
If the patient is on doxorubicin therapy, allow at least 7 days following administration of a dose of doxorubicin before
blood draw.
Specimen Required: Collect: CellSave®Preservative tube (ARUP supply # 44867). Available online through eSupply using ARUP ConnectTM or contact
ARUP Client Services at (800) 522-2787. Due to stability, collect Monday-Thursday only.
Specimen Preparation: Transport 20 mL whole blood. (Min: 10 mL) The minimum collection amount will not allow for repeat testing.
Storage/Transport Temperature: Room temperature. Do not refrigerate or freeze.
Remarks: HISTORY IS REQUIRED. Specify type of metastatic cancer (breast, colorectal, or prostate). This assay is FDA approved only for these
3 metastatic cancers; other types will not be tested.
Unacceptable Conditions: Frozen or refrigerated specimens. Specimens not collected in the CellSave® tube or collected in expired CellSave®
tubes. Short draws.
CPT Code(s):
0279T
2003302
Citalopram, Serum or Plasma
CITALO
Methodology:
Specimen Preparation: Separate from cells within 2 hours of draw. Transfer 1 mL serum or plasma into an ARUP Standard Transport Tube. (Min:
0.4 mL)
CPT Code(s):
82491
0080011
Citric Acid, Serum
Methodology:
Spectrophotometry/Enzymatic
Specimen Preparation: Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 1 mL)
Stability: Ambient: 8 hours; Refrigerated: 18 days; Frozen: 1 month
CPT Code(s):
82507
CITRIC S
0020852
Citric Acid, Urine
CITRIC U
Methodology:
Specimen Required: Collect: 24-hour urine. Refrigerate during collection. Also acceptable: Random urine.
Specimen Preparation: Adjust pH to less than or equal to 2 by adding 6M HCl. Transfer a 4 mL aliquot of urine to an ARUP Standard
Transport Tube. (Min: 0.5 mL) Record total volume, collection time interval, and pH on transport tube and test request form. Also acceptable:
Specimens previously preserved with boric acid.
Remarks:
Stability: Ambient: 8 hours; Refrigerated: 1 week; Frozen: Indefinitely
CPT Code(s):
82507
2006261
Citrin Deficiency (SLC25A13) Sequencing
CITRIN FGS
Methodology:
CPT Code(s):
83891 Isolation; 83898 x19 Amplification; 83904 x19 Sequencing; 83909 capillary electrophoresis; 83912 Interpretation and report -Additional
2007069
Citrullinemia, Type I (ASS1) Sequencing
ASS1 FGS
Methodology:
CPT Code(s):
83891 Isolation; 83898 x14 Amplification; 83904 x14 Sequencing; 83909 Capillary electrophoresis, 83912 Interpretation and report. Additional
0099336
Clomipramine and Metabolite
CLOMIP
Methodology:
Page | 158
CPT Code(s):
80299 x2
0090055
Clonazepam
CLON
Methodology:
Stability: After separation from cells: Ambient: 6 weeks; Refrigerated: 6 weeks; Frozen: 2 months
CPT Code(s):
80154
0091362
Clonidine, Serum or Plasma
Methodology:
CPT Code(s):
80299
CLONIDI SP
0091223
Clonidine, Urine
Methodology:
CPT Code(s):
80299
CLONID UR
0090196
Clorazepate (Assayed as Nordiazepam)
CLORAZ
Methodology:
CPT Code(s):
80154
0060140
Clostridium difficile Culture with Reflex to Cytotoxin Cell Assay
MC CDIF
Methodology:
Specimen Required: Collect: Stool: Transfer 5 mL to an unpreserved stool transport vial (ARUP supply #40910). OR place 5 mL in enteric transport media (CaryBlair) (ARUP supply #29799). (Min: 1 mL) Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800)
522-2787.
Tissue: Transfer specimen immediately into anaerobe transport media (ARUP supply #16426).
Specimen Preparation: Transfer 5 mL stool to an unpreserved stool transport vial (ARUP supply #40910). OR place 5 mL stool in enteric transport
media (Cary-Blair) (ARUP supply #29799). (Min: 1 mL) Available online through eSupply using ARUP Connector contact ARUP Client Services
at (800) 522-2787. Storage/Transport Temperature: Frozen.
Storage/Transport Temperature: Stool: Frozen. Tissue: Room Temperature.
Unacceptable Conditions: Multiple specimens (more than one in 24 hours), formed stools, or stool in PVA or formalin.
Stability: Unpreserved or preserved Stool: Ambient: 2 hours; Refrigerated: 48 hours; Frozen: 1 week. Tissue: Ambient: 48 hours; Refrigerated:
Unacceptable; Frozen: Unacceptable.
CPT Code(s):
87075; if reflexed add 87230
2002552
Clostridium difficile Cytotoxin Antibody by Neutralization
Methodology:
Antibody Neutralization
Specimen Preparation: Separate serum from cells. Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 1 mL)
CPT Code(s):
87230
CDIFF AB
0060851
Clostridium difficile Cytotoxin Cell Assay
CDIFTX
Methodology:
Cell Culture/Neutralization
Specimen Preparation: Transfer 1 mL stool to an unpreserved stool transport vial (ARUP supply #40910). Available online through eSupply using
ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 0.5 mL)
Unacceptable Conditions: Specimens in preservatives. Specimens submitted on swabs.
Stability: Ambient: 2 hours; Refrigerated: 72 hours; Frozen at -20°C: 72 hours; Frozen at -70°C: 1 week
CPT Code(s):
87230
2002838
Clostridium difficile toxin B gene (tcdB) by PCR
CDIFF PCR
Methodology:
Specimen Required: Collect: Soft or liquid stool.
Specimen Preparation: Transfer 1 mL stool to a clean, unpreserved transport vial (ARUP Supply# 40910). Available online through eSupply using
ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 0.5 mL).
Page | 159
CPT Code(s):
Stability: Ambient: 48 hours; Refrigerated: 5 days; Frozen: 1 month
87493
0065146
Clostridium difficile Toxins (A & B) by EIA
CDIFF
Methodology:
Specimen Preparation: Transfer 5 mL stool to an unpreserved stool transport vial (ARUP Supply #40910). Available online through eSupply using
ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 1 mL)
Unacceptable Conditions: Formed stool. Specimens in media or preservatives.
Stability: Unpreserved: Ambient: 2 hours; Refrigerated: 72 hours; Frozen: 1 week
CPT Code(s):
87324
0098930
Clozapine
CLOZAPINE
Methodology:
Stability: After separation from cells: Ambient: 5 weeks; Refrigerated: 2 months; Frozen: 2 months
CPT Code(s):
80299
2006476
Clozapine and Metabolite, Serum or Plasma
CLOZMET SP
Methodology:
Specimen Required: Collect: Plain red or lavender (EDTA) or pink (K2EDTA).
Stability: Ambient: 8 Days; Refrigerated: 1 Month; Frozen: 1 Month
CPT Code(s):
80299
0099231
Methodology:
Cobalt, Blood
COBALT B
CPT Code(s):
83018
2005549
Methodology:
Cobalt, Joint Fluid
CO F
High concentrations of iodine may interfere with elemental testing. Patients should abstain from iodine-containing
medications or contrast agents for at least 1 month prior to specimen collection for elemental testing.
Specimen Required: Collect: Joint fluid. The use of betadine-like topical antiseptics should be avoided during specimen collection.
Specimen Preparation: Transfer 1 mL joint fluid to an ARUP Trace Element-Free Transport Tube (ARUP supply #43116). Available online
through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 0.5 mL)
Unacceptable Conditions: Separator tubes and gels. Fluid collected after administration of a gadolinium (Gd) containing contrast media (may
occur with MRI studies).
CPT Code(s):
83018
0025037
Methodology:
Cobalt, Serum or Plasma
COBALT S
Specimen Required: Collect: Royal blue (no additive) or Royal blue (EDTA)
Specimen Preparation: Centrifuge; Do not allow serum to remain on cells. Transfer 2 mL serum or plasma to an ARUP Trace Element-Free
Transport Tube (ARUP supply #43116). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800)
522-2787. (Min: 0.5 mL)
Unacceptable Conditions: Separator tubes. Specimens that are not separated from the red cells, or clot, within 6 hours.
CPT Code(s):
83018
0025032
Methodology:
Page | 160
Cobalt, Urine
COBALT U
Storage/Transport Temperature: Refrigerated. Also acceptable: Ambient or frozen.
CPT Code(s):
83018
0050137
Coccidioides Antibodies, IgG & IgM by ELISA
COCCI G/M
Methodology:
Specimen Required: Collect: Serum separator tube OR CSF.
Specimen Preparation: Separate serum from cells ASAP or within 2 hours of collection. Transfer 2 mL serum OR CSF to an ARUP Standard
Transport Tube. (Min: 0.15 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the
acute specimens. Please Mark specimens plainly as "acute" or "convalescent."
CPT Code(s):
86635 Cocci IgM; 86635 Cocci IgG
0050710
Coccidioides Antibodies Panel, CSF by CF, ID, ELISA
COCCI CSF
Methodology:
Semi-Quantitative Complement Fixation/Qualitative Immunodiffusion/Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Specimen Preparation: Transfer two 1 mL aliquots of CSF to individual ARUP Standard Transport Tubes. (Min: 0.3 mL per aliquot)
Unacceptable Conditions: Grossly bloody or hemolyzed specimens.
CPT Code(s):
86635 Cocci Ab (CF); 86635 Cocci Ab (ID); 86635 Cocci IgG (EIA); 86635 Cocci IgM (EIA)
0050588
Coccidioides Antibodies Panel, Serum by CF, ID, ELISA
COCCI PAN
Methodology:
Semi-Quantitative Complement Fixation/Qualitative Immunodiffusion/Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Specimen Preparation: Separate serum from cells ASAP or within 2 hours of collection. Transfer two 1 mL aliquots of serum to individual ARUP
Standard Transport Tube. (Min: 0.3 mL per aliquot) Parallel testing is preferred and convalescent specimens must be received within 30 days
from receipt of the acute specimens. Mark specimens plainly as "acute" or "convalescent."
Unacceptable Conditions: Other body fluids. Contaminated, hemolyzed, or severely lipemic specimens.
CPT Code(s):
86635 Cocci Ab (CF); 86635 Cocci Ab (ID); 86635 Cocci Ab, IgG (EIA); 86635 Cocci Ab, IgM (EIA)
0050170
Coccidioides Antibody by CF
COCCI
Methodology:
Transport Tube. (Min: 0.15 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of acute
CPT Code(s):
86635
0050183
Coccidioides Antibody by ID
Methodology:
Specimen Preparation: Transfer 0.5 mL serum OR CSF to an ARUP Standard Transport Tube (Min: 0.15 mL)
Unacceptable Conditions: Bloody or grossly hemolyzed specimens.
CPT Code(s):
86635
COCCI-PPT
0050179
Coccidioides Antibody, IgG by ELISA
Methodology:
Specimen Preparation: Transfer 1 mL serum OR CSF to an ARUP Standard Transport Tube. (Min: 0.15 mL)
CPT Code(s):
86635
COCCI G
0050178
Coccidioides Antibody, IgM by ELISA
COCCI M
Methodology:
Transport Tube. (Min: 0.15 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute
Page | 161
CPT Code(s):
86635
0062225
Coccidioides immitis Identification by DNA Probe
MC CP
Methodology:
Nucleic Acid Probe
Specimen Required: Collect: Actively growing fungal isolate in pure culture.
Specimen Preparation: Transport sealed container pure culture on non-blood containing fungal medium. Place each specimen in an individually
sealed bag.
Storage/Transport Temperature: Room temperature. If culture is suspected to be of a microorganism listed by the IATA as infectious to humans,
submit according to Biological Substance, Category A, shipping guidelines.
Remarks: Results may be delayed if growth of the organism is inadequate.
Unacceptable Conditions: Mixed or non-viable organisms. Agar plate.
CPT Code(s):
87149
0081119
Methodology:
Coenzyme Q10, Total
COENZ Q10
Patient should fast overnight prior to specimen collection. Patient may have water. It is not necessary to discontinue
nutritional supplements prior to this test.
Specimen Required: Collect: Plasma separator tube, green (sodium or lithium heparin), serum separator tube, or plain red.
Specimen Preparation: Protect from light within one hour of collection and during storage and shipment. Transfer 1 mL serum or plasma to an
ARUP Amber Transport Tube. (Min: 0.3 mL)
Unacceptable Conditions: Specimens other than heparinized plasma or serum. Hemolyzed specimens. Specimens exposed to repeated freeze/thaw
cycles.
Stability: After separation from cells: Ambient: Unacceptable; Refrigerated: 3 weeks; Frozen: 1 month
CPT Code(s):
82491
0050175
Cold Agglutinins
COLD
Methodology:
Semi-Quantitative Hemagglutination
Specimen Preparation: Keep in warm water (37°C) until processed for transport by laboratory; refrigeration of specimen before separation of
serum from cells will adversely affect test results. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.25 mL)
Unacceptable Conditions: Plasma or CSF. Refrigerated whole blood. Contaminated, severely hemolyzed, or lipemic, specimens.
CPT Code(s):
86157
2003839
Collagen IV by Immunohistochemistry
COLL 4 IHC
Methodology:
CPT Code(s):
88342
0093167
Methodology:
Colorado Tick Fever Antibodies, IgG & IgM, IFA
Immunofluorescence Assay
CPT Code(s):
86790 IgG; 86790 IgM
COLOR TICK
2005373
Complement Activity, Alternative Pathway (AH50)
AH50
Methodology:
Semi-Quantitative Radial Immunodiffusion
Specimen Preparation: Allow specimen to clot for one hour at room temperature. Separate serum from cells ASAP or within 2 hours of collection.
Transfer 1 mL serum to an ARUP Standard Transport Tube and freeze. (Min: 0.3 mL)
Unacceptable Conditions: Specimen types other than serum. Refrigerated or room temperature specimens. Specimens left to clot at refrigerated
temperature. Specimens exposed to repeated freeze/thaw cycles.
CPT Code(s):
86162
0050198
Complement Activity Enzyme Immunoassay, Total
Methodology:
Page | 162
CH50
CPT Code(s):
Unacceptable Conditions: Separator tubes. Specimens left to clot at 2-8°C. Specimens exposed to repeated freeze/thaw cycles. Non-frozen
specimens.
86162
0099078
Complement Component 1, Functional
C1
Methodology:
Quantitative Hemolytic Assay
Specimen Preparation: Allow blood to clot at room temperature for 20-60 minutes. Separate serum from cells and freeze on dry ice or at -70°C
within 2 hours. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 1 mL)
CPT Code(s):
86161
0099130
Complement Component 1Q Level
COMP 1Q
Methodology:
Radial Immunodiffusion
Unacceptable Conditions: Grossly hemolyzed, hyperlipemic, or room temperature specimens. Serum or non-EDTA plasma.
CPT Code(s):
86160
0050148
Complement Component 2
C2
Methodology:
Transfer 1 mL serum to an ARUP Standard Transport Tube and freeze immediately. (Min: 0.3 mL)
Unacceptable Conditions: Non-frozen specimens. Specimens exposed to repeated freeze/thaw cycles. Specimens left to clot at refrigerated
temperature.
CPT Code(s):
86160
0050150
C3
Methodology:
Specimen Preparation: Allow specimen to clot at room temperature. Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5
mL serum to an ARUP Standard Transport Tube and freeze. (Min: 0.3 mL)
Unacceptable Conditions: Specimens left to clot at refrigerated temperature. Specimens exposed to repeated freeze/thaw cycles.
CPT Code(s):
86160
2003304
Complement Component 3A
COMP 3A
Methodology:
Radioimmunoassay
Specimen Preparation: Separate from cells within 1 hour of draw. Transfer 1 mL plasma to an ARUP Standard Transport Tube. Freeze at -70or on
dry ice immediately. (Min: 1 mL)
Stability: Ambient: Unacceptable; Refrigerated: Unacceptable: Frozen at -70°C: 1 month
CPT Code(s):
86160
0050155
C4
Methodology:
Specimen Required: Collect: Serum separator tube. Also acceptable: Lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin).
Specimen Preparation: Allow specimen to clot at room temperature. Separate serum from cells ASAP or within 2 hours of collection and freeze.
Transport 0.5 mL serum. (Min: 0.3 mL)
Stability: Ambient: 48 hours; Refrigerated: 48 hours; Frozen: 2 weeks (avoid repeated freeze/thaw cycles)
CPT Code(s):
86160
2003180
Complement Component 4A
COMP 4A
Methodology:
Radioimmunoassay
Specimen Preparation: Separate from cells within 1 hour of draw. Transfer 1 mL plasma to an ARUP Standard Transport Tube. Freeze at -70°C or
on dry ice immediately. (Min: 1 mL)
Stability: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: Frozen at -70°C: 1 year
CPT Code(s):
86160
Page | 163
0050156
C5
Methodology:
Transfer 1 mL serum to an ARUP Standard Transport Tube and freeze immediately. (Min: 0.3 mL) Plasma is not recommended.
Unacceptable Conditions: Non-frozen specimens. Specimens exposed to repeated freeze/thaw cycles. Specimens left to clot at refrigerated
temperature.
CPT Code(s):
86160
0099072
COMP 6
Methodology:
Specimen Preparation: Separate plasma from cells within 1 hour. Transfer 1 mL plasma to an ARUP Standard Transport Tube and freeze on dry
ice or at -70(Min: 1 mL)
CPT Code(s):
86160
0099131
Complement Component 6 Functional
COMP 6 F
Methodology:
Specimen Preparation: Allow to clot at room temperature for 20-60 minutes. Transfer 1 mL serum to an ARUP Standard Transport Tube. Separate
from clot and freeze at -70°C or on dry ice within 2 hours of draw. (Min: 1 mL)
CPT Code(s):
86161
0099073
Methodology:
Specimen Required: Collect: Plain red. Also acceptable: Lavender (EDTA).
CPT Code(s):
86160
COMP 7
0099121
COMP 7 F
Methodology:
Specimen Preparation: Allow blood to clot at room temperature for 20-60 minutes. Separate from clot. Transfer 1 mL serum to an ARUP Standard
Transport Tube and freeze at -70°C or on dry ice within 2 hours of draw. (Min: 1 mL)
Remarks: CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered. Allow blood to clot at room temperature
for 20 to 60 minutes. Must be separated from clot and frozen at -70° C or on dry ice within 2 hours of draw.
CPT Code(s):
86161
0099074
Methodology:
Stability: Ambient: 1 week; Refrigerated: 2 weeks; Frozen: 3 weeks
CPT Code(s):
86160
COMP 8
0099133
COMP 8 F
Methodology:
Hemolytic Assay
CPT Code(s):
86161
0099076
Methodology:
CPT Code(s):
86160
Page | 164
COMP 9
0099120
COMP 9 F
Methodology:
CPT Code(s):
86161
2003499
Complement Component C9 (CCC9) by Immunohistochemistry
CCC9 IHC
Methodology:
CPT Code(s):
88342
0050149
Complement Components 3 and 4
C3C4
Methodology:
Specimen Preparation: Allow specimen to clot at room temperature. Separate serum from cells ASAP or within 2 hours of collection. Transfer 1
mL serum to an ARUP Standard Transport Tube and freeze. (Min: 0.6 mL)
Stability: Ambient: 8 hours; Refrigerated: 24 hours; Frozen: 2 weeks (avoid repeated freeze/thaw cycles)
CPT Code(s):
86160 C3; 86160 C4
0051720
Complement Factor B
COMP FAC B
Methodology:
Specimen Preparation: Allow specimen to clot for 30 minutes to one hour at refrigerated temperature. Separate serum from cells ASAP or within 2
hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube and place on refrigerant pack or freeze immediately. (Min: 0.3
mL)
Unacceptable Conditions: Room temperature specimens. Specimens exposed to repeated freeze/thaw cycles.
Stability: After separation from cells: Ambient: Unacceptable, Refrigerated: 48 hours; Frozen: 1 year
CPT Code(s):
86160
0020408
Comprehensive Metabolic Panel
CMP
Methodology:
Quantitative Ion-Selective Electrode/Quantitative Enzymatic/Quantitative Spectrophotometry
Specimen Preparation: Protect from light. Allow serum tube to clot completely at room temperature. Separate serum or plasma from cells ASAP
or within 30 minutes of collection. Transfer 1 mL serum or plasma to an ARUP Amber Transport Tube. (Min: 0.5 mL)
Unacceptable Conditions: EDTA, citrate, oxalate, or sodium fluoride/potassium oxalate.
Stability: After separation from cells: Ambient: Calcium and CO2: 4 hours, All others: 24 hours; Refrigerated: 1 week; Frozen: 6 months
CPT Code(s):
80053
2002282
Methodology:
Congenital Adrenal Hyperplasia Panel, 11-Beta Hydroxylase Deficiency
CAH 11-B HYDROX
Collect between 6-10 a.m.
Specimen Required: Collect: Serum separator tube or green (sodium or lithium heparin). Also acceptable: Lavender (EDTA) or pink (K2EDTA).
CPT Code(s):
82157 Androstenedione; 83498 17-Hydroxyprogesterone; 84403 Testosterone; 82634 11-Deoxycortisol;
82626 Dehydroepiandrosterone.
2002283
Methodology:
Congenital Adrenal Hyperplasia Panel, 21-Hydroxylase Deficiency
CAH 21 HYDROX
Specimen Required: Collect: Serum separator tube or green (sodium or lithium heparin). Also acceptable: Lavender (EDTA) or pink (K2EDTA).
Stability: After separation from cells: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 6 months
CPT Code(s):
82157 Androstenedione; 83498 17-Hydroxyprogesterone; 84143 17-Hydroxypregnenolone; 82626 Dehydroepiandrosterone
Page | 165
2002029
Methodology:
Congenital Adrenal Hyperplasia Treatment Panel
Specimen Required: Collect: Serum separator tube or green (sodium or lithium heparin). Also acceptable: Lavender (EDTA).
Specimen Preparation: Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min 0.5 mL)
CPT Code(s):
82157 Androstenedione; 83498 17-Hydroxyprogesterone; 84403 Total Testosterone
CAH RX PANEL
2006220
Congenital Amegakaryocytic Thrombocytopenia (CAMT) Sequencing
CAMT FGS
Methodology:
Sequencing
CPT Code(s):
83891 Isolation; 83898 x32 Amplification; 83894 x32 Gel electrophoresis; 83904 x32 Sequencing; 83892 x3 Digestion; 83912 Interpretation and
report.
0051668
Connective Tissue Diseases Profile
CONN
Methodology:
Semi-Quantitative Multiplex Bead Assay
Tube. (Min: 0.3 mL)
Unacceptable Conditions: Plasma or other body fluids. Bacterially contaminated specimens.
CPT Code(s):
86235 x6 ENAs; 83516 Centromere; 83516 RIBPP
0051374
Connexin 26 (GJB2), Sequencing
Methodology:
Nucleic Acid Probe/Fluorescence Signal Amplification/Polymerase Chain Reaction/Sequencing
CPT Code(s):
83891 Isolation: 83898 x2 Amplification; 83904 x3 Sequencing; 83909 Capillary electrophoresis; 83912 Interpretation and report.
CX26SEQ
Consultation, Cytopathology
Methodology:
Microscopy
Specimen Required: Collect: Submit pap slides, nongynecological slide preparations, any special slides, paraffin-embedded block if applicable, copy of preliminary
cytopathology report, clinical history, and a brief explanatory note. If special studies are anticipated such as cytogenetics, flow cytometry, PCR,
FISH, EM, IHC, IF, etc., submit additional tissue in appropriate fixative if required.
CPT Code(s):
Contact your ARUP Business Development Manager or the Anatomic Pathology Business Development Manager at (800) 522-2787 for more
information.
88321 Basic, consultation and report on referred material; or 88323 Moderate, consultation and report on referred material requiring slide
preparation; or 88325 Complex, consultation, with review of records and specimens, and report on referred material. Additional billing may apply
if special studies are indicated.
Consultation, Dermatopathology
Methodology:
Microscopy
Specimen Required: Collect: Submit hematoxylin and eosin slides, any special stain slides, paraffin-embedded block if applicable, copy of preliminary cytopathology
report, clinical history and a brief explanatory note. If special studies are anticipated such as cytogenetics, flow cytometry, PCR, FISH, EM, IHC,
IF, etc., submit additional tissue in appropriate fixative if required.
CPT Code(s):
Contact your ARUP Business Development Manager or the Anatomic Pathology Business Development Manager (800) 522-2787 for more
information.
Consultation, Head and Neck
Methodology:
Microscopy
Specimen Required: Collect: Submit hematoxylin and eosin slides, any special stain slides, paraffin-embedded block , copy of preliminary pathology report, clinical
history and a brief explanatory note. If special studies are anticipated such as cytogenetics, flow cytometry, PCR, FISH, EM, IHC, IF, etc., submit
additional tissue in appropriate fixative if required.
CPT Code(s):
Methodology:
Page | 166
information.
Consultation, Hematopathology
Microscopy
Specimen Required: Collect: Transport prepared slides (Hematoxylin and eosin, Wright stained, etc.) any special stain slides, paraffin-embedded block, copy of
preliminary pathology report, clinical history and a brief explanatory note. If special studies are anticipated such as cytogenetics, flow cytometry,
PCR, FISH, EM, IHC, IF, etc., submit additional tissue in appropriate fixative if required.
CPT Code(s):
Contact your ARUP Business Development Manager at (800) 522-2787 for more information.
Consultation, Neuropathology
Methodology:
Microscopy
Specimen Required: Collect: Submit hematoxylin and eosin slides, any special stain slides, paraffin-embedded block, copy of preliminary pathology report, clinical
history and brief explanatory note. If special studies are anticipated such as cytogenetics, flow cytometry, PCR, FISH, EM, IHC, IF, etc., submit
additional tissue in appropriate fixative if required.
CPT Code(s):
information.
Consultation, Surgical Pathology
Methodology:
Microscopy
Specimen Required: Collect: Transport hematoxylin and eosin slides, any special stain slides, and paraffin-embedded block. Include copy of preliminary pathology
report, clinical history and brief explanatory note. If special studies are anticipated such as cytogenetics, flow cytometry, PCR, FISH, EM, IHC,
IF, etc., submit additional tissue in appropriate fixative if required.
CPT Code(s):
information.
if special studies are included.
0020694
Copper, Liver
CU-LIVER
Methodology:
Specimen Required: Collect: Liver tissue obtained with an 18 gauge needle.
Specimen Preparation: Transport at least a 1 cm long specimen. Tissue can be fresh, paraffin-embedded, or dried. Also acceptable: Formalinfixed. Specimens other than paraffin-embedded should be stored and transported in a metal-free container such as a royal blue (no additive).
Unacceptable Conditions: Specimens less than 0.25 mg (dry weight). Paraffin blocks that have been processed with Hollandes or other coppercontaining stain.
Stability: Paraffin block, preserved (formalin), or dried: Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Indefinitely
Fresh tissue: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: Indefinitely
CPT Code(s):
82525
2007252
Copper, RBC
COPPER RBC
Methodology:
Specimen Required: Collect: Royal blue (EDTA).
Specimen Preparation: Separate cells within 2 hours of collection. Transfer 2 mL RBCs to an ARUP Trace Element-Free Transport Tube (ARUP
supply #43116). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 0.7 mL)
Stability: Ambient: Unacceptable; Refrigerated: 2 weeks; Frozen: 2 weeks
CPT Code(s):
82525
0020096
Methodology:
Copper, Serum
COPPER
Specimen Required: Collect: Royal blue (no additive) or Royal blue (EDTA)
Specimen Preparation: Centrifuge; do not allow serum or plasma to remain on cells. Transfer 2 mL serum or plasma to an ARUP Trace ElementFree Transport Tube (ARUP supply #43116). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800)
522-2787. (Min: 0.5 mL)
Unacceptable Conditions: Separator tubes and specimens that are not separated from the red cells or clot within 6 hours.
CPT Code(s):
82525
0020596
Methodology:
Copper, Serum Free (Direct)
COPPER F
Specimen Required: Collect: Royal blue (no additive).
Specimen Preparation: Centrifuge. Transfer 2.5 mL serum to an ARUP Trace Element-Free Transport Tube. (Min: 1.5 mL) Do not allow serum to
remain on cells.
Unacceptable Conditions: Separator tubes. Specimens that are not separated from the red cells or clot.
CPT Code(s):
82525
Page | 167
0020461
Methodology:
Copper, Urine
COPPER U
CPT Code(s):
82525
2003292
Methodology:
CordStat 12 Reflexive Panel
CORD 12
Qualitative Enzyme-Linked Immunosorbent Assay/Quantitative Gas Chromatography-Mass Spectrometry/Liquid Chromatography-Tandem Mass
Spectrometry
Specimen Required: Collect: Umbilical cord. Collection instructions are provided with kit (ARUP Supply #46990). Available online through eSupply using ARUP
Specimen Preparation: Avoid any contact of ethanol liquid or vapor with the umbilical cord. Do not place in formalin. Transport 6-inch to 8-inch
segment of umbilical cord.
Remarks: Submissions require tamper evident seal to be placed on the specimen collection container. Unsealed containers will be rejected.
CPT Code(s):
80101 x12 Drug screen; 80103 Tissue preparation; if positive, add 80102 Drug confirmation and 80103 Tissue preparation for each procedure
0098513
Corticosteroid Binding Globulin (CBG)
Methodology:
Radioimmunoassay
Stability: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 2 years
CPT Code(s):
84449
CORTICO BG
2003250
Methodology:
Cortisol by LC-MS/MS, Serum or Plasma
CORT TMS
It is recommended that the specimen be collected between 6-11 a.m.
Specimen Required: Collect: Serum separator tube, lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin).
Specimen Preparation: Separate serum or plasma from cells ASAP or within 2 hours of collection. Transport 1 mL serum or plasma. (Min: 0.5
mL)
Stability: After separation from cells: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 6 months
CPT Code(s):
82533
0092100
Cortisol/Cortisone Urine Free by LC-MS/MS
CORTURATIO
Methodology:
Specimen Preparation: Transport one 4 mL aliquot of urine. (Min: 1 mL) Record total volume and collection time interval on transport tube and
test request form.
Unacceptable Conditions: Room temperature specimens. Acidified specimens or specimens with preservatives.
Stability: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 1 month
CPT Code(s):
82530 Cortisol; 83789 LC-MS/MS
0098391
Cortisol, Free
FCORTS
Methodology:
Equilibrium Dialysis/Quantitative Electrochemiluminescent Immunoassay
Specimen Required: Collect: Plain red or serum separator tube. Also acceptable: Lavender (EDTA) or pink (K2EDTA).
Specimen Preparation: Centrifuge specimen. Separate serum or plasma from cells within 2 hours of collection. Transfer 1 mL serum or plasma to
an ARUP Standard Transport Tube. (Min: 0.6 mL) Label plainly as a.m. or p.m. collection.
Unacceptable Conditions: Specimens collected in plasma separator tubes containing heparin. Grossly hemolyzed or heparinized specimens.
CPT Code(s):
82530
0081117
Methodology:
Cortisol, Saliva
CORT SAL
Do not collect specimen within 60 minutes after eating a meal, within 12 hours after consuming alcohol, immediately after
brushing teeth or after any activity that may cause gums to bleed. Rinse mouth thoroughly with water 10 minutes before specimen collection.
Recommended collection time is between 11:00 p.m. - 1:00 a.m.
Specimen Required: Collect: Saliva. Swab must be completely saturated to ensure sufficient volume for testing.
Specimen Preparation: Transfer saturated swab to plain (non-citric acid) cotton Salivette® collection device (ARUP Supply #41252). Record the
time of collection on the test request form, and on Salivette® transport container.
Page | 168
CPT Code(s):
Unacceptable Conditions: Specimens not collected using the Salivette® collection device. Sodium azide preservative. Specimens with pH values
greater than 9.0 or less than 3.5 must be recollected. Specimens visibly contaminated with blood, cellular debris, food particles, or mucus.
82533
0070030
Cortisol, Serum or Plasma
CORTISOL
Methodology:
Specimen Required: Collect: Serum separator tube or plasma separator tube. Also acceptable: Green (sodium or lithium heparin).
Unacceptable Conditions: Saliva (refer to Cortisol, Saliva, ARUP test code 0080117).
CPT Code(s):
82533
0097222
Cortisol Urine Free by LC-MS/MS
CORT UF
Methodology:
Specimen Preparation: Transport one 4 mL aliquot of urine. (Min: 1 mL) Record total volume and collection time interval on transport tube and
test request form.
Unacceptable Conditions: Room temperature specimens. Acidified specimens or specimens with preservatives.
Stability: Ambient: Unacceptable; Refrigerated: 2 weeks; Frozen: 6 months
CPT Code(s):
82530
2003252
Methodology:
Cortisone by LC-MS/MS, Serum or Plasma
CONE TMS
Specimen Required: Collect: Serum separator tube, lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin).
mL)
CPT Code(s):
83491
0060360
Corynebacterium diphtheriae Culture
MC DIPH
Methodology:
Specimen Required: Collect: Nasopharynx, throat, or wound swab.
Swab nasopharynx and throat at the site of membrane or inflammation to significantly increases recovery. Swab base of cleansed wound, if
present.
Specimen Preparation: Place swab in bacterial transport media.
CPT Code(s):
2007081
Cotinine Screen, Urine
Methodology:
Enzyme Multiplied Immunoassay Technique
Specimen Required: Collect: Random urine
Specimen Preparation: Transfer 4 mL urine with no additives to an ARUP Standard Transport Tube. (Min: 2 mL)
Unacceptable Conditions: Specimens exposed to repeated freeze/thaw cycles
Stability: Ambient: 10 days; Refrigerated: 10 days; Frozen: 8 months
CPT Code(s):
80101
2003102
Methodology:
Coxiella burnetii (Q-Fever) Antibodies, IgG & IgM by IFA with Reflex to Titer
Stability: Ambient: 4 days; Refrigerated: 1 week; Frozen: 1 month
CPT Code(s):
86638 x4; if reflexed add 86638 per titer performed
COTININE
C BURNETII
0050462
Coxiella burnetii (Q-Fever) Antibody IgG, Phase I & II by IFA
Q-F 1,2
Methodology:
specimens. Mark specimens plainly as "acute" and "convalescent."
CPT Code(s):
86638 Q-Fever Phase I; 86638 Q-Fever Phase II
Page | 169
0050463
Coxiella burnetii (Q-Fever) Antibody IgG, Phase I by IFA
Q-F I
Methodology:
Unacceptable Conditions: Urine. Contaminated, hemolyzed, or severely lipemic specimens.
CPT Code(s):
86638
0050464
Coxiella burnetii (Q-Fever) Antibody IgG, Phase II by IFA
Q-F II
Methodology:
Unacceptable Conditions: Urine. Contaminated, hemolyzed, or severely lipemic specimens.
CPT Code(s):
86638
2003097
Methodology:
Coxiella burnetii (Q-Fever) Antibody, IgM by IFA with Reflex to Titer
Semi-Quantitative Immunofluorescence Assay
Stability: Ambient: 4 days; Refrigerated: 1 week; Frozen: 1 month
CPT Code(s):
86638 x2; if reflexed add 86638 per titer performed
2002932
Coxsackie A Antibodies (A-2, 4, 7, 9, 10 & 16 Serotypes)
Methodology:
Complement Fixation
Specimen Preparation: Transfer 2 mL serum to an ARUP standard transport tube. (Min: 1 mL)
CPT Code(s):
86658 x6 A-2, 4, 7, 9, 10 and 16 serotypes
COXIELLA B
COX A AB
0050503
Coxsackie A9 Virus Antibodies by CF
COX A9
Methodology:
CPT Code(s):
86658
0060055
Coxsackie B Virus Antibodies
COX B
Methodology:
Semi-Quantitative Serum Neutralization
Specimen Required: Collect: Serum separator tube or plain red. OR CSF.
Specimen Preparation: Separate serum from cells within 2 hours of collection. Transfer 1 mL serum or CSF to an ARUP Standard Transport Tube.
(Min: 0.3 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of acute specimens. Mark
CPT Code(s):
86658 x6 Coxsackie (B1, B2, B3, B4, B5, and B6)
2002328
Creatine Disorders Panel, Plasma or Serum
CRTN DIS P
Methodology:
Liquid Chromatography/Tandem Mass Spectrometry
Specimen Required: Collect: Green (sodium or lithium heparin), lavender (EDTA), plain red, or serum separator tube.
Specimen Preparation: Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport
Unacceptable Conditions: Specimens exposed to more than one freeze/thaw cycle.
CPT Code(s):
82540 Creatine; 83789 Guanidinoacetic acid
2002333
Creatine Disorders Panel, Urine
Methodology:
Specimen Required: Collect: Random or timed urine.
Page | 170
CRTN DIS U
CPT Code(s):
Specimen Preparation: Transfer 2 mL urine to an ARUP Standard Transport Tube and freeze immediately. (Min: 0.5 mL)
82540 Creatine, 82570 Creatinine, 83789 Guanidinoacetic acid
0020414
Creatine Kinase Isoenzymes
CKISO
Methodology:
Quantitative Enzymatic/Electrophoresis
Specimen Preparation: Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) CK-MB and CK-BB are quite labile;
specimens should be frozen if the assay cannot be performed within 24 hours.
Remarks: This test will detect CK macroenzymes.
Unacceptable Conditions: Specimens preserved in citrate, EDTA, fluoride, heparin, or iodoacetate. Room temperature specimens.
Stability: After separation from cells: Ambient: Unacceptable; Refrigerated: 24 hours; Frozen: 2 weeks (avoid repeated freeze/thaw cycles)
CPT Code(s):
82552 Creatine kinase isoenzymes; 82550 Creatine kinase, total
0080480
Creatine Kinase, MB
CK MB
Methodology:
Specimen Required: Collect: Green (sodium or lithium heparin), plasma separator tube, serum separator tube.
Specimen Preparation: SST needs to sit for 15-20 minutes for proper clot formation and to assure the absence of fibrin in the serum which can
interfere with this assay. Centrifuge and remove from cells ASAP or within 2 hours of collection. Specimens must be free of all particulate matter
which can interfere with the assay. Transfer 2 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Remarks: CK-MB is quite labile. CK-MB relative percent will be calculated only if Creatine Kinase, Total, Serum or Plasma (ARUP test
code 0020010) is ordered.
Unacceptable Conditions: Specimens exposed to repeated freeze/thaw cycles.
CPT Code(s):
82553
0020010
Creatine Kinase, Total, Serum or Plasma
CK
Methodology:
Specimen Required: Collect: Plasma preparation tube or serum separator tube.
Specimen Preparation: Allow specimen to clot completely at room temperature. Separate serum or plasma from cells ASAP. Transfer 1 mL serum
or plasma to an ARUP Standard Transport Tube. (Min: 0.2 mL)
Unacceptable Conditions: Specimens collected in potassium oxalate or sodium fluoride. Grossly hemolyzed specimens.
CPT Code(s):
82550
2002340
Creatine, Serum or Plasma
CRTN SP
Methodology:
Specimen Required: Collect: Plain red, serum separator tube, green (sodium or lithium heparin), or lavender (EDTA).
CPT Code(s):
82540
2001875
Creatine Transport, Fibroblasts
CRTN FIBRO
Methodology:
Radioassay
Specimen Required: Collect: Fibroblasts from skin biopsy.
Specimen Preparation: Transport two T-25 flasks of fibroblasts from skin biopsy. Cells should be kept in 37°C incubator until shipped.
Storage/Transport Temperature: CRITICAL ROOM TEMPERATURE. Must call lab before shipping. Ship Monday-Thursday only.
Remarks: Clinical information is needed for appropriate interpretation. Biochemical Genetics Patient History Form is available on the
ARUP Web site at http://www.aruplab.com/patienthistory or by contacting ARUP Client Services.
Unacceptable Conditions: Frozen or refrigerated specimens. Specimens in improper media. Dead cells.
CPT Code(s):
84238
2002343
Creatine, Urine
Methodology:
Specimen Preparation: Transfer 2 mL urine to an ARUP Standard Transport Tube and freeze immediately. (Min: 0.5 mL)
CPT Code(s):
82540
CRTN URINE
0020473
Creatinine, 24-Hour Urine
UCRT
Methodology:
Specimen Required: Collect: 24-hour urine. Specimen must be refrigerated during collection. Also acceptable: Random urine (no reference intervals).
Specimen Preparation: Transfer one 3 mL aliquot to an ARUP Standard Transport Tube. (Min: 0.5 mL) Record total volume and collection time
interval on transport tube and test request form. Also acceptable: Specimens previously preserved with 6M HCl, boric acid, or 5% NaOH.
Page | 171
CPT Code(s):
Stability: Ambient: 24 hours; Refrigerated: 4 days; Frozen: 6 months
82570
0020509
Creatinine, Body Fluid
Methodology:
Spectrophotometry
Specimen Preparation: Centrifuge and separate to remove cellular material. Transport 1 mL body fluid. (Min: 0.2 mL)
Stability: Ambient: 5 days; Refrigerated: 1 month; Frozen: 6 months
CPT Code(s):
82570
CRT-FL
0020474
Creatinine Clearance, Urine
CRTCL
Methodology:
Quantitative Spectrophotometry/Enzymatic
Specimen Required: Collect: 24-hour urine. Specimen must be refrigerated during collection. AND plasma separator tube or serum separator tube, collected within 48
hours of initiating urine collection.
Specimen Preparation: Transfer one 3 mL aliquot from a well-mixed 24-hour collection (Min: 0.5 mL) AND 1 mL serum or plasma (Min: 0.2 mL)
to individual ARUP Standard Transport Tubes. Record total volume and collection time interval on transport tube and test request form.
Unacceptable Conditions: Random urine collections.
Stability: Serum: (after separation from cells) Ambient: 4 hours; Refrigerated: 1 week; Frozen: 6 months
Urine: Ambient: 24 hours; Refrigerated: 4 days; Frozen: 6 months.
CPT Code(s):
82575
0020025
Creatinine, Serum or Plasma
CRT
Methodology:
collection. Transfer 1 mL plasma or serum or plasma to an ARUP Standard Transport Tube. (Min: 0.2 mL)
Unacceptable Conditions: Specimens obtained through catheters used to infuse hyperalimentation fluid. Specimens with potassium oxalate/sodium
fluoride, citrate, or EDTA as anticoagulants.
CPT Code(s):
82565
0091485
Cresols, Urine
Methodology:
Specimen Required: Collect: Random urine in a preservative-free container.
Unacceptable Conditions: Specimens preserved with Benzoic Acid.
CPT Code(s):
84600
CRESOL URN
2001613
Crohn Disease Prognostic Panel
CROHN PAN
Methodology:
Tube. (Min: 0.3 mL)
Unacceptable Conditions: Plasma, other body fluids, grossly icteric, heat-inactivated, grossly hemolyzed, severely lipemic, or contaminated
specimens.
(avoid repeated freeze/thaw cycles)
CPT Code(s):
86671 gASCA IgG; 83516 Lam Ag IgG; 83516 Man Ag IgG; 83516 Chito Ag IgA
0050190
Methodology:
Cryofibrinogen
CRYO FIB
Qualitative Cold Precipitation
Specimen Required: Collect: Whole blood drawn in a pre-warmed (37°C) syringe. Specimen may be drawn directly into a pre-warmed lt. blue (sodium citrate) or
black (sodium citrate).
Specimen Preparation: Maintain whole blood at 37°C from collection to transport; do not refrigerate or freeze at any time. Immediately
after blood has been obtained, transfer specimen to a pre-warmed blue (sodium citrate) or black (sodium citrate) (if not used for collection).
Separate plasma from cells using a 37°C centrifuge, if possible. Transfer 3 mL plasma to an ARUP Standard Transport Tube. (Min: 1 mL)
Remarks: Proper collection and transport of specimen is critical to the outcome of the assay. Quantities less than 3 mL may affect the sensitivity of
the assay.
Unacceptable Conditions: Refrigerated or frozen specimens. Heparinized specimens. Grossly hemolyzed or lipemic specimens.
Stability: After separation from cells: Ambient: 1 week; Refrigerated: Unacceptable; Frozen: Unacceptable
CPT Code(s):
82585
0050185
Methodology:
Cryoglobulin, Qualitative
Qualitative Cold Precipitation
Specimen Required: Collect: Plain red tube.
Page | 172
CRYGB
CPT Code(s):
Specimen Preparation: 1) Draw approximately 7 mL of blood into a pre-warmed (37°C) plain red tube. Alternatively: draw into a pre-warmed
(37°C) syringe and immediately transfer blood to a pre-warmed (37°C) plain red tube. 2) Maintain collected blood at 37°C until clotting is
complete. 3) Separate serum from cells within 1 hour of collection. Transfer 3 mL serum to an ARUP Standard Transport Tube. (Min: 1 mL) See
Remarks.
Remarks: Proper collection and transport of specimen is critical to the outcome of the test. Submitting quantities less than 3 mL may affect the
sensitivity of the test.
Unacceptable Conditions: Plasma. Refrigerated or frozen specimens. Serum separator tubes (SST or clot-activating tubes). Grossly hemolyzed or
lipemic specimens.
82595
2002403
Methodology:
Cryoglobulin, Qualitative with Reflex to IFE Typing and Quantitative IgA, IgG, and IgM
CRYO TYPING
Qualitative Cold Precipitation/Qualitative Immunofixation Electrophoresis/Quantitative Nephelometry
Specimen Required: Collect: Whole blood drawn in a pre-warmed (37°C) syringe. Specimen may be drawn directly into a pre-warmed plain red.
Specimen Preparation: Maintain whole blood at 37°C until clotting is complete; do not refrigerate or freeze at any time. Immediately after
blood has been obtained, transfer specimen to a pre-warmed plain red (if not used for collection). Separate plasma from cells using a 37°C
centrifuge, if possible. Transfer 3 mL serum to an ARUP Standard Transport Tube. (Min: 3 mL)
Remarks: Proper collection and transport of specimen is critical to the outcome of the assay. Quantities less than 3 mL may affect the sensitivity of
the assay.
Unacceptable Conditions: Plasma. Refrigerated or frozen specimens. Separator tubes. Grossly hemolyzed or lipemic specimens.
CPT Code(s):
82595 Cryoglobulin; if reflexed, add 86334 IFE and 82784 x3 (IgA, IgG, IgM)
2002063
Methodology:
Cryoglobulin, Qualitative, with Reflex to Quantitative IgA, IgG, and IgM
CRYGB QNT
Qualitative Cold Precipitation/Quantitative Nephelometry
Specimen Required: Collect: Plain red tube.
Specimen Preparation: 1) Draw approximately 7 mL of blood into a pre-warmed (37 degrees C) plain red tube. Alternatively: draw into a prewarmed (37 degrees C) syringe and immediately transfer blood to a pre-warmed (37 degrees C) plain red tube. 2) Maintain collected blood at 37
degrees C until clotting is complete (up to 1 hour). 3) Separate serum from cells ASAP. Transfer 3 mL serum to an ARUP Standard Transport
Tube. (Min: 1 mL) See Remarks.
Remarks: Proper collection and transport of specimen is critical to the outcome of the test. Submitting quantities less than 3 mL may affect the
sensitivity of the test.
Unacceptable Conditions: Plasma. Refrigerated or frozen specimens. Serum separator tubes (SST or other clot-activating tubes). Grossly
hemolyzed or lipemic specimens.
CPT Code(s):
82595 Cryoglobulin; if reflexed, add 82784 x3 (IgA, IgG, IgM)
0098947
Methodology:
Cryptococcus Antibody
CPT Code(s):
86641
CRYPTO AB
0050195
Cryptococcus Antigen, CSF
CRY CSF
Methodology:
Specimen Preparation: Transfer 1 mL CSF to a sterile ARUP Standard Transport Tube (ARUP supply #43115). Available online through eSupply
using ARUP Connector contact ARUP Client Services at (800) 522-2787. (Min: 0.25 mL)
Stability: Ambient: 1 hour; Refrigerated: 72 hours; Frozen: Indefinitely
CPT Code(s):
87327
0050196
Cryptococcus Antigen, Serum
CRY BLD
Methodology:
Specimen Preparation: Separate serum from cells. Transfer 1 mL serum to a sterile ARUP Standard Transport Tube (ARUP supply # 43115).
Available online through eSupply using ARUP Connector contact ARUP Client Services at (800) 522-2787. (Min: 0.25 mL)
Stability: Ambient: 1 hour; Refrigerated: 72 hours; Frozen: Indefinitely
CPT Code(s):
87327
Page | 173
0060045
Cryptosporidium Antigen by EIA
CRYSPOR
Methodology:
Specimen Preparation: Preserve 5 g stool in 10 percent formalin within one hour of collection (ARUP supply #16355). Available online through
eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 1 g)
Unacceptable Conditions: Specimens in any other preservative than indicated above.
Stability: Ambient: 9 months; Refrigerated: 9 months; Frozen: Unacceptable
CPT Code(s):
87328
0009500
Crystals (Local Clients Only)
CRYSTALS
Methodology:
Microscopy/Polarizing Microscopy
Specimen Required: Collect: Synovial or bile fluid in liquid EDTA or sodium heparin.
Specimen Preparation: Transport 1 mL synovial or bile fluid. (Min: 0.5 mL)
Unacceptable Conditions: Any fluid other than synovial or bile. Synovial or bile fluids collected in powdered EDTA or powdered lithium heparin.
Specimens sent with needle. Frozen specimens.
CPT Code(s):
89060
0092572
Methodology:
Cutaneous Direct Immunofluorescence, Biopsy
Direct Immunofluorescence
(Direct Fluorescent Antibody Stain)
Specimen Required: Collect: Tissue, skin, or mucous membrane.
Specimen Preparation: Transport epidermis/epithelium and dermis tissue (optimal 4-5 mm) in Michel's (or Zeus) medium.
Unacceptable Conditions: Formalin-fixed tissue.
Stability: Ambient: 10 days; Refrigerated: 10 days; Frozen: Unacceptable
CPT Code(s):
88346 x5 IgG, IgM, IgA, C3, & fibrinogen
CUTDIF
0090060
Cyanide
CYAN
Methodology:
Quantitative Colorimetry
Specimen Required: Collect: Green (sodium or lithium heparin). Also acceptable: Lavender (EDTA) or pink (K2EDTA or K3EDTA).
Specimen Preparation: Do not freeze. Transport 4 mL whole blood in original collection container. (Min: 3 mL) Also acceptable: Transfer
specimen to an ARUP Standard Transport Tube.
Unacceptable Conditions: Serum or plasma. Frozen or refrigerated specimens. Clotted or hemolyzed specimens.
Stability: Ambient: 72 hours (if tightly capped); Refrigerated: Unacceptable; Frozen: Unacceptable
CPT Code(s):
82600
0070181
Methodology:
Cyclic AMP, Nephrogenous
CAMP-NEPH
Refer to individual components.
Specimen Required: Collect: Lavender (EDTA) or pink (K2EDTA) AND urine, timed or random.
Specimen Preparation: Separate plasma from cells and freeze ASAP or within 2 hours of collection. Transfer 1 mL plasma to an ARUP Standard
Transport Tube and freeze immediately. (Min: 0.1 mL) AND transfer 5 mL urine to ARUP Standard Transport Tubes. (Min: 0.1 mL)
CPT Code(s):
82030 Cyclic AMP, urine; 82030 Cyclic AMP, plasma
0070180
Cyclic AMP, Plasma
CAMP
Methodology:
Stability: After separation from cells: Ambient: Unacceptable; Refrigerated: 1 hour; Frozen: 3 months
CPT Code(s):
82030
0070485
Cyclic AMP, Urine
CAMP-U
Methodology:
Specimen Required: Collect: Random urine (unpreserved). Also acceptable: 24-hour urine. Collect in container with 10 mL 6M HCl.
Specimen Preparation: Transfer 5 mL aliquot of urine to ARUP Standard Transport Tubes. (Min: 1 mL) Record total volume and collection time
interval on transport tube and test request form.
Stability: Ambient: 2 hours; Refrigerated: 24 hours; Frozen: 3 months
CPT Code(s):
82030
Page | 174
0055256
Cyclic Citrullinated Peptide (CCP) Antibody, IgG
CCP IGG
Methodology:
Tube. (Min: 0.3 mL)
Unacceptable Conditions: Urine or plasma. Contaminated, hemolyzed, grossly icteric, heat-inactivated, or severely lipemic specimens.
CPT Code(s):
86200
2003842
Cyclin D1, SP4 by Immunohistochemistry
CYCSP4 IHC
Methodology:
CPT Code(s):
88342
0091303
Cyclobenzaprine (Flexeril), Serum or Plasma
Methodology:
Gas Chromatography
Stability: Ambient: 1 week; Refrigerated: 16 days; Frozen: 1 year
CPT Code(s):
80299
0091155
Cyclobenzaprine (Flexeril), Urine
Methodology:
Stability: Ambient: 1 week; Refrigerated: 16 days; Frozen: 1 year
CPT Code(s):
82491
Cyclosporine A by Tandem Mass Spectrometry
Pre-dose (trough) levels should be drawn.
Specimen Preparation: Transfer 1 mL well-mixed whole blood to a plastic vial. (Min: 0.25 mL)
Unacceptable Conditions: Serum or plasma. Specimens left at room temperature for longer than 24 hours. Clotted specimens.
CPT Code(s):
80158
CYCLOBENZA
CYCLOBEN U
0070035
Methodology:
CYA
0058902
Methodology:
C2CYA
Cyclosporine A, C2 by Tandem Mass Spectrometry
Two hour post-dose level should be drawn.
Unacceptable Conditions: Serum or plasma. Specimens left at room temperature for longer than 24 hours. Clotted specimens.
CPT Code(s):
80158
0081344
CYFRA 21-1 (Cytokeratin 19 Fragment), Serum
CYFRA
Methodology:
Specimen Preparation: Allow serum specimen to clot completely at room temperature. Separate serum from cells ASAP or within 2 hours of
collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Unacceptable Conditions: Plasma. Icteric, lipemic, or hemolyzed specimens.
Stability: After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 2 months (avoid repeated freeze/thaw cycles)
CPT Code(s):
86316
0095229
Cystatin C, Serum
CYSTAT C
Methodology:
Specimen Required: Collect: Serum separator tube or plasma separator tube.
Page | 175
CPT Code(s):
Stability: After separation from cells: Ambient: 48 hourS; Refrigerated: 1 week; Frozen: 2 months
82610
0056003
Cystic Fibrosis (CFTR) 5T Mutation
IVS-8
Methodology:
CPT Code(s):
83891 Isolation; 83900 Multiplex amplification; 83901 x31 Additional amplification; 83914 x2 OLA; 83909 Capillary electrophoresis; 83912
Interpretation and report
0050098
Cystic Fibrosis (CFTR) 3199del6 Mutation
CF3199DEL6
Methodology:
CPT Code(s):
83891 Isolation; 83898 x2 Amplification; 83896 x4 Nucleic acid probes; 83912 Interpretation and report - Additional CPT code modifiers may be
2001933
Cystic Fibrosis (CFTR) 32 Mutations
CF PAN
Methodology:
Polymerase Chain Reaction/Oligonucleotide Ligation/Fragment Analysis
Remarks: Patient History Form is available on the ARUP Web site or by contacting Client Services at (800) 522-2787.
Stability: Ambient: 3 days; Refrigerated: 1 week; Frozen: Unacceptable
CPT Code(s):
83891 Isolation; 83900 Amplification; 83901 x30 Multiplex amplification; 83914 x32 OLA; 83909 Capillary electrophoresis; 83912 Interpretation
2001969
Cystic Fibrosis (CFTR) 32 Mutations, Atypical
CF PAN 5T
Methodology:
Stability: Ambient: 3 days; Refrigerated: 1 week; Frozen: Unacceptable
CPT Code(s):
83891 Isolation; 83900 Amplification; 83901 x30 Multiplex amplification; 83914 x33 OLA; 83909 Capillary electrophoresis; 83912 Interpretation
2001970
Cystic Fibrosis (CFTR) 32 Mutations, Fetal
CF PAN FE
Methodology:
Specimen Required: Collect: Fetal Specimen: Two T-25 flasks at 80% confluent of cultured amniocytes. If the client is unable to culture amniocytes, this can be
arranged by contacting ARUP Client Services at (800) 522-2787.
Maternal Specimen: Lavender (EDTA) or yellow (ACD Solution A or B).
Specimen Preparation: Cultured amniocytes: Fill flasks with culture media. Transport two T-25 flasks at 80% confluent of cultured amniocytes.
Backup cultures must be retained at the client's institution until testing is complete.
Maternal Specimen: Transport 3 mL whole blood.
Storage/Transport Temperature: Cultured amniocytes: CRITICAL ROOM TEMPERATURE. Must be received within 48 hours of shipment
due to lability of cells.
Maternal Specimen: Room temperature. Ship with the fetal specimen.
Remarks: Maternal sample is recommended for proper test interpretation; order Maternal Cell Contamination. Patient History Form is
available on the ARUP Web site or by contacting ARUP Client Services.
Stability: Fetal: Ambient: 48 hours; Refrigerated: Unacceptable; Frozen: Unacceptable
Maternal: Ambient: 72 hours; Refrigerated: 1 week; Frozen: Unacceptable
CPT Code(s):
83891 Isolation; 83900 Multiplex amplification; 83901 x30 Additional amplification; 83914 x32 Mutation identification by OLA; 83909 Capillary
electrophoresis; 83912 Interpretation and report. FCC: 83900 Multiplex amplification; 83901 x14 Additional amplification; 83909 Capillary
electrophoresis. If MCC Maternal Cell (0050608) is performed, add: 83891 Isolation; 83900 Multiplex amplification; 83901 x14 Additional
amplification; 83909 Capillary electrophoresis; 83912 Interpretation and report - Additional CPT code modifiers may be required for procedures
2001968
Cystic Fibrosis (CFTR) 32 Mutations with Reflex to Sequencing
CF PAN-SEQ
Methodology:
Polymerase Chain Reaction/Oligonucleotide Ligation/Fragment Analysis/Sequencing
CPT Code(s):
Interpretation and report. If reflexed to sequencing, add 83891 Isolation; 83898 x32 Amplification; 83904 x32 Sequencing; 83909 Capillary
electrophoresis - Additional CPT code modifiers may be required for procedures performed to test for oncologic or inherited disorders.
2001967
Cystic Fibrosis (CFTR) 32 Mutations with Reflex to Sequencing and Reflex to Deletion/Duplication
CF COMPR
Methodology:
Polymerase Chain Reaction/Oligonucleotide Ligation/Fragment Analysis/Sequencing/Multiplex Ligation-dependent Probe Amplification
Page | 176
CPT Code(s):
Interpretation and report. If reflexed to sequencing, add 83891 Isolation; 83898 x32 Amplification; 83904 x32 Sequencing; 83909 Capillary
electrophoresis. If reflexed to Deletion/Duplication, add 83896 Nucleic acid probes; 83898 Amplification; 83914 Extension; 83909 Capillary
electrophoresis - Additional CPT code modifiers may be required for procedures performed to test for oncologic or inherited disorders.
0051642
Cystic Fibrosis (CFTR) Deletion/Duplication
CFTRDELDUP
Methodology:
Multiplex Ligation-dependent Probe Amplification
Remarks: Patient History Form is available on the ARUP Web site or by contacting ARUP Client Services at (800) 522-2787.
CPT Code(s):
83891 Isolation; 83896 Nucleic Acid Probes; 83898 Amplification; 83914 Extension; 83909 Capillary Electrophoresis; 83912 Interpretation and
0051110
Cystic Fibrosis (CFTR) Sequencing
CF-CFTR
Methodology:
CPT Code(s):
83891 Isolation; 83898 x32 Amplification; 83904 x32 Sequencing; 83909 Capillary electrophoresis; 83912 Interpretation and report. Additional
0051640
Cystic Fibrosis (CFTR) Sequencing with Reflex to Deletion/Duplication
CFTR FGA
Methodology:
Polymerase Chain Reaction/Sequencing/Multiplex Ligation-dependent Probe Amplification
CPT Code(s):
Sequencing: 83891 Isolation; 83898 x32 Amplification; 83904 x32 Sequencing; 83909 Capillary electrophoresis; 83912 Interpretation and report.
If reflexed to Deletion/Duplication, add 83896 Nucleic Acid Probes; 83898 Amplification; 83914 Extension; 83909 Capillary electrophoresis.
Additional CPT code modifiers may be required for procedures performed to test for oncologic or inherited disorders.
0056006
Cystic Fibrosis Cis-Trans(CFTR) R117H and 5T Mutations
CFCIS-TRAN
Methodology:
Polymerase Chain Reaction/Oligonucleotide Ligation
CPT Code(s):
83891 Isolation; 83900 Amplification; 83901 Multiplex amplification; 83914 x4 Mutation identification; 83909 Separation and identification;
83912 Interpretation and report - Additional CPT code modifiers may be required for procedures performed to test for oncologic or inherited
disorders.
0060130
Cystic Respiratory Culture
Methodology:
Specimen Required: Collect: Sputum from cystic fibrosis patient.
Specimen Preparation: Transfer sputum to a sterile container. Place each specimen in an individually sealed bag.
Unacceptable Conditions: Multiple specimens (more than one in 24 hours).
CPT Code(s):
87070
MC CYST
0055284
Cysticercosis Antibody, IgG by ELISA
CYST SER
Methodology:
Specimen Preparation: Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.1 mL) Parallel testing is preferred and convalescent
specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as acute or convalescent.
Unacceptable Conditions: CSF. Contaminated, heat-inactivated, hemolyzed, icteric, or lipemic specimens.
CPT Code(s):
86682
0055285
Cysticercosis Antibody, IgG by ELISA (CSF)
Methodology:
Unacceptable Conditions: Serum. Contaminated, heat-inactivated, hemolyzed, icteric, or lipemic specimens.
CPT Code(s):
86682
Page | 177
CYST CSF
0055283
Cysticercosis Antibody, IgG by Western Blot
CYST WB
Methodology:
Tube. (Min: 0.1 mL)
Unacceptable Conditions: CSF. Contaminated, heat-inactivated, hemolyzed, icteric, or severely lipemic specimens.
CPT Code(s):
86682
0055282
Cysticercosis Antibody, IgG by Western Blot (CSF)
Methodology:
Unacceptable Conditions: Specimen types other than CSF. Contaminated or heat-inactivated specimens.
CPT Code(s):
86682
CYSTCSF WB
0081106
Cystine Quantitative, Urine
QNT CYS U
Methodology:
Specimen Required: Collect: 24-hour or other timed urine collection. Avoid dilute urine when possible. Refrigerate 24-hour/timed specimens during collection.
Specimen Preparation: Mix urine well. Transfer 8 mL aliquot urine to ARUP Standard Transport Tubes and freeze immediately. (Min: 3 mL)
Record total volume and collection time interval on transport tube and test request form.
therapy), drug therapy, and family history. Biochemical Genetics Patient History Form is available on the ARUP Web site or by contacting
CPT Code(s):
82131
0081105
Cystinuria Panel
CYS PAN
Methodology:
Specimen Required: Collect: Random urine. Avoid dilute urine when possible.
Specimen Preparation: Mix urine well. Transfer 8 mL urine to ARUP Standard Transport Tubes and freeze immediately. (Min: 3 mL)
therapy), drug therapy, and family history. Biochemical Genetics Patient History Form is available on the ARUP web site or by contacting
CPT Code(s):
82136
0051103
Cytochrome P450 2C9 (CYP2C9) 2 Mutations
CYP2C9
Methodology:
Polymerase Chain Reaction/DNA Hybridization/Electrochemical Detection
CPT Code(s):
83891 Isolation; 83892 Enzymatic Digestion, 83900 Amplification, 83901 Additional Amplification x13, 88384 Array-based evaluation of
multiple molecular probes; 11 through 50 probes, 83912 Interpretation and report - Additional CPT code modifiers may be required for procedures
0051104
Cytochrome P450 2C19 (CYP2C19) 9 Mutations
CYP2C19
Methodology:
Polymerase Chain Reaction/Primer Extension
CPT Code(s):
83891 Isolation; 83900 Multiplex Amplification; 83901 x4 Additional Amplification; 83914 x18 Extension; 83912 Interpretation and report Additional CPT code modifiers may be required for procedures performed to test for oncologic or inherited disorders.
0051232
Cytochrome P450 2D6 (CYP2D6) 14 Mutations and Gene Duplication
CYP 2D6
Methodology:
Polymerase Chain Reaction/Primer Extension
CPT Code(s):
83891 Isolation; 83900 Amplification multiplex; 83901 x6 Amplification; 83914 x12 Mutation identification; 83912 Interpretation and report Additional CPT code modifiers may be required for procedures performed to test for oncologic or inherited disorders.
2003414
Cytogenomic SNP Microarray
Methodology:
Genomic Microarray (Oligo-SNP Array)
Specimen Required: Collect: Green (sodium heparin) or lavender (EDTA). Peripheral blood required.
Page | 178
CMA SNP
CPT Code(s):
83891 Isolation; 88386 x 6, Array-based evaluation of multiple molecular probes, 251-500
2006325
Cytogenomic SNP Microarray - Oncology
Methodology:
Specimen Required: Collect: Green (sodium heparin). Bone marrow or peripheral blood required.
Specimen Preparation: Transport 3 mL bone marrow. (Min: 1 mL) or 5 mL peripheral blood (Min: 2 mL)
CPT Code(s):
CMA ONC
2006267
Cytogenomic SNP Microarray Buccal Swab
CMA BUCCAL
Methodology:
Specimen Required: Collect: One buccal swab using the Oracollect collection kit ensuring the sponge tip does not come into contact with any suface prior to collection.
Donor should not eat, drink, smoke or chew gum for 30 minutes before collecting oral sample.
Specimen Preparation: Transport Buccal swab in ORAcollect Collection kit
Unacceptable Conditions: Specimen exposed to extreme temperatures
Stability: Ambient: 72 hours; Refrigerated: 72 hours;
CPT Code(s):
2003851
Cytokeratin 5,6 (CK 5,6) by Immunohistochemistry
CYTO56 IHC
Methodology:
2003854
Cytokeratin 7 (CK 7) by Immunohistochemistry
CYTO 7 IHC
Methodology:
CPT Code(s):
88342
2003493
Cytokeratin 8,18 Low Molecular Weight (CAM 5.2) by Immunohistochemistry
CAM5.2 IHC
Methodology:
CPT Code(s):
88342
2003845
CYTO19 IHC
Methodology:
Page | 179
CPT Code(s):
88342
2003848
CYTO20 IHC
Methodology:
CPT Code(s):
88342
0051394
Cytokine Panel 12 by MAFD
CYT 12 SE
Methodology:
Quantitative Multiplex Bead Assay
Specimen Required: Collect: Serum separator tube, plain red, or green (lithium heparin).
Storage/Transport Temperature: CRITICAL FROZEN. Additional specimens must be submitted when multiple tests are ordered.
Remarks:
Unacceptable Conditions: Refrigerated specimens. Contaminated or heat inactivated specimens.
Stability: After separation from cells: Ambient: 30 minutes; Refrigerated: Unacceptable; Frozen: 1 year
CPT Code(s):
83520 x 12
0051524
Cytokine Panel, Monokines by MAFD
CYT MON SE
Methodology:
Remarks:
Unacceptable Conditions: Refrigerated specimens. Contaminated or heat-inactivated specimens.
CPT Code(s):
83520 x 4
0051408
Cytokine Panel, TH1 by MAFD
CYT TH1 SE
Methodology:
Remarks:
CPT Code(s):
83520 x 4
0051518
Cytokine Panel, TH2 by MAFD
CYT TH2 SE
Methodology:
Remarks:
CPT Code(s):
83520 x 4
0051540
Methodology:
Cytokine Production by Mononuclear Cells in Response to Mitogen Stimulation, 12 Cytokines
CYT 12 LY
Cell Culture/Quantitative Multiplex Bead Assay
healthy individual who is not biologically related to the patient, and drawn at approximately the same time as and under similar conditions to the
patient specimen.
Specimen Required: Collect: Yellow (ACD Solution A) (patient) AND yellow (ACD Solution A) (control). Patient and control samples must be collected within 48
hours of test performance.
Specimen Preparation: Transport 10 mL whole blood (patient) AND 10 mL whole blood (control) in original collection tubes. (Min: 7 mL whole
blood (patient) AND 7 mL whole blood (control)). LIVE CELLS REQUIRED. Do not refrigerate or freeze.
Infant Minimum: 3 mL whole blood (patient) AND 7 mL whole blood (control).
Remarks:
Unacceptable Conditions: Frozen or refrigerated specimens. Specimens in transport longer than 48 hours.
CPT Code(s):
86353 x3 Lymphocyte transformation; 83520 x12 Cytokines
Page | 180
0051574
Methodology:
Cytokine Production by Mononuclear Cells in Response to Mitogen Stimulation, Interferon gamma
IFNG L DO
patient specimen.
Remarks:
CPT Code(s):
86353 x3 Lymphocyte transformation; 83520 Cytokine
0051580
Methodology:
Cytokine Production by Mononuclear Cells in Response to Mitogen Stimulation, Interleukin 1 beta
IL1B L DO
patient specimen.
Remarks:
CPT Code(s):
0051571
Methodology:
Cytokine Production by Mononuclear Cells in Response to Mitogen Stimulation, Interleukin 2
IL2 L DO
patient specimen.
Remarks:
CPT Code(s):
0051572
Methodology:
Cytokine Production by Mononuclear Cells in Response to Mitogen Stimulation, Interleukin 2 Receptor (Soluble)
IL2R L DO
patient specimen.
CPT Code(s):
0051576
Methodology:
IL4 L DO
patient specimen.
Remarks:
Page | 181
CPT Code(s):
0051577
Methodology:
IL5 L DO
patient specimen.
Remarks:
CPT Code(s):
0051581
Methodology:
IL6 L DO
patient specimen.
CPT Code(s):
0051582
Methodology:
IL8 L DO
patient specimen.
Remarks:
CPT Code(s):
0051578
Methodology:
IL10 L DO
patient specimen.
Remarks:
CPT Code(s):
0051579
Methodology:
IL13 L DO
patient specimen.
Remarks:
Page | 182
CPT Code(s):
0051566
Methodology:
Cytokine Production by Mononuclear Cells in Response to Mitogen Stimulation, Monokines
CYT MON LY
patient specimen.
Remarks:
CPT Code(s):
0051558
Methodology:
Cytokine Production by Mononuclear Cells in Response to Mitogen Stimulation, TH1 Cytokines
CYT TH1 LY
patient specimen.
Remarks:
CPT Code(s):
0051562
Methodology:
Cytokine Production by Mononuclear Cells in Response to Mitogen Stimulation, TH2 Cytokines
CYT TH2 LY
patient specimen.
Remarks:
CPT Code(s):
0051583
Methodology:
Cytokine Production by Mononuclear Cells in Response to Mitogen Stimulation, Tumor Necrosis Factor alpha
TNFA L DO
patient specimen.
Remarks:
CPT Code(s):
8290122
Methodology:
Cytology, Anal
Microscopy
Indications: Cytologic screening for anal squamous intraepithelial lesions (ASIL).
Specimen Required: Collect: Anal sampling.
AN
Supplies: Glass microscope slide for smears or, preferably, collected in SurePath™ or PreservCyt® collection fluid. Available online through
eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787.
Also required: ARUP Cytology test request form and a black lead lab pencil.
Page | 183
CPT Code(s):
8209701
Methodology:
Specimen Required:
CPT Code(s):
Collection Procedure: To obtain an anal sampling, moisten the Dacron® swab with water, not lubricant. The Dacron® swab should be inserted
approximately 1.5 to 2 inches into the anal canal. It is important to use Dacron® and not a cotton swab, as cells tend to cling to cotton and do not
release easily into cytology collection fluids. Once inserted deep enough into the anus (necessary in order to collect both rectal columnar and anal
squamous cells) the swab should be pulled out, applying some pressure to the wall of the anus, rotating the swab in a spiral motion along the way.
The cells collected can be placed in a cytology collection fluid (preferred) or spread on a glass slide and immediately spray-fixed. The preferred
method of collection is in SurePath™ collection fluid. The collection device should be thoroughly rinsed and swirled in the vial. The vial should
be labeled with the patient's first and last name and collection date, placed in a specimen bag, and shipped to the Cytology Lab. The specimen
must be accompanied by an ARUP Cytology test request form with the requested test marked.
Storage/Transport Temperature: If collected in SurePath™, Cytolyt®, or CytoRich™:
Unacceptable Conditions: Specimens submitted in expired reagents. Refer to the Specimen Rejection section of the Specimen Transport Guide.
Stability: SurePath™: Ambient: 4 weeks
PreservCyt®: Ambient: 3 weeks
Depending on collection method: 88112 Selective cellular enhancement with interpretation or 88160 Smear with interpretation - Additional CPT
codes may apply if special studies are required.
Cytology, Body Cavity Fluid
CF
Microscopy
Collect: Refer to Cytology, Body Cavity Fluid Collection for specific collection and transportation guidelines.
88108 Concentration and interpretation and/or 88106 Cytopathology, filter; 88305 Cell block. Additional CPT codes may apply if special studies
are required.
Cytology, Body Cavity Fluid Collection
Body cavity fluids are commonly evaluated for the presence of malignant cells from metastatic disease. Body cavity fluids
in general are relatively easy to obtain and are relatively difficult to compromise. However, in some instances, due to a large number of
inflammatory cells, specimens may degenerate rapidly. In addition, if large amounts of protein are present, the specimen may clot, trapping
diagnostic cells within the clot. These fluids include pleural, peritoneal, pericardial, synovial, and pelvic washing.
Specimen Required: Collect: Body Cavity Fluids
Indications: Detection and characterization of malignant cells in body cavity fluids.
Specimen Required: 10 mL (or more) of fluid obtained from an appropriately performed paracentesis.
Supplies: Standard paracentesis equipment. Clean collection container of appropriate size. Fixative (50% ethyl alcohol).
Collection Procedure: Using standard paracentesis technique, obtain a fluid specimen from the desired body cavity. If necessary, move the
patient into multiple positions to suspend cellular material in the fluid. A minimum of 10 mL of specimen is desirable for optimal cytologic
evaluation. If other studies are required, withdraw a fraction of the specimen and submit it to the appropriate laboratory separately, following their
guidelines for specimen collection. Heparin may be added to the specimen to reduce clotting. Place 3 units of heparin per mL capacity of the
collection container. Agitate the container to coat the sides with heparin. Rinse the paracentesis instrument with a small amount of heparin to
prevent clotting of specimen before it is put into the collection container. Add specimen to the heparinized container. Gently agitate to thoroughly
mix the specimen and heparin. Label the container with the patient's first and last name, date of birth, specimen type, and collection date. Submit
the specimen to the Cytopathology Laboratory along with the completed Cytology test request form. If transport of the specimen will be delayed
more than 24 hours, add an equal volume of 50% ethyl alcohol (if sample size is too large to accommodate this volume, a well mixed aliquot of
the specimen with an equal volume of fixative may be utilized). If transport time will be less than 24 hours, or fixative is not available, the
specimen should be refrigerated or kept on wet ice until transport to the lab.
Pelvic Washing
Indications: Detection and characterization of malignant cells in pelvic washing.
Specimen Required: 10 mL (or more) of fluid obtained from an appropriately performed washing.
Supplies: Standard suction equipment. Clean collection container of appropriate size. Fixative (50% ethyl alcohol).
Collection Procedure: Using appropriate sterile technique during intra-abdominal surgery, instill a physiologic solution into the pelvic cavity.
Lavage the area of interest. Aspirate the solution and place in a clean container. Label the container with the patient's first and last name, date of
birth, specimen type and collection date. Submit the specimen and completed Cytology test request form to the Cytopathology Laboratory. If
transport of the specimen will be delayed more than 24 hours, add an equal volume of 50% ethyl alcohol. If transport time will be less than 24
hours, or fixative is not available, the specimen should be refrigerated or kept on wet ice until transport to the lab.
8209700
Methodology:
Cytology, Breast Nipple Secretion
Microscopy
Indications: Detection of malignant cells in nipple discharge specimens.
Specimen Required: Collect: Direct smear of nipple discharge.
BN
Supplies: Two clean glass slides (single-end frosted), fixative (spray fixative or 95% ethanol), test request form.
CPT Code(s):
8280005
Methodology:
Page | 184
Collection Procedure: Label the two slides with the patient's first and last name, date of birth and specimen site in pencil on the frosted end.
Collect a small amount of nipple secretion directly onto one of the slides. Oppose a second glass slide onto the first, allowing the collected
material to provide surface tension between the two slides, and then gently and quickly pull the two slides apart in a horizontal motion to distribute
the material in a thin film over both slides. The smears should be immediately fixed either by spray fixative or in 95% ethyl alcohol to prevent airdrying. Submit the specimen and the completed test request form to the Cytopathology Laboratory.
Unacceptable Conditions: Refer to the Specimen Rejection section in the Specimen Transport Guide.
Stability: Fixed slides: Indefinitely
88104
Cytology, Bronchoalveolar Lavage, Malignancy
Microscopy
Use this for all nonopportunistic infection indications (e.g., malignancy).
BAL 2
Specimen Required: Collect: Refer to Cytology, Bronchoalveolar Lavage Specimen Collection for specific collection and transportation guidelines.
CPT Code(s):
88108 Concentration and interpretation or 88112 Selective cellular enhancement with interpretation and/or 88106 Cytopathology, filter.
Additional CPT codes may apply if special studies are required.
8209703
Methodology:
Cytology, Cerebrospinal Fluid
CS
Microscopy
Indications: Detection and characterization of malignant cells in the central nervous system. In cytology, cerebrospinal
fluid is most commonly evaluated to detect and characterize malignancy which may have gained access to the central nervous system. While in
most individuals, CSF specimens are relatively easy to obtain, in some individuals collection may require radiographic guidance. In addition, due
to lack of nutrients in this fluid, cells may rapidly degenerate rendering morphologic evaluation less than optimal if adequate care is not taken.
Specimen Required: Collect: Minimum of 3 mL cerebrospinal fluid (CSF). (10 mL CSF minimum required for immunologic marker studies)
Supplies: Standard cerebrospinal fluid collection equipment. Clean, clear 10 mL collection container for CSF. Fixative (50% ethyl alcohol).
Collection Procedure: Using standard CSF procedure, collect 3 mL of CSF. In general, morphology of cells within the CSF can be adequately
maintained with prompt refrigeration for 24 hours. Although a fresh specimen is preferred, if a longer time period between collection and
processing is anticipated, the specimen may be preserved by adding an equal volume of 50% ethyl alcohol to the specimen. Label the container
with the patient's first and last name, date of birth, specimen type and collection date. Submit the specimen to the Cytopathology Laboratory
along with the completed Cytology test request form.
CPT Code(s):
Note: Specimens submitted for immunocytochemical testing must be submitted fresh.
Stability: Refrigerated: 72 hours
88108 Concentration and interpretation or 88112 Selective cellular enhancement with interpretation and/or 88106 Cytopathology, filter.
Additional CPT codes may apply if special studies are required.
8209713
Methodology:
Cytology, Conjunctival Scraping
Microscopy
Indications: Detection and characterization of inflammatory/infectious processes of the conjunctiva.
Specimen Required: Collect: Direct smear of material collected from the conjunctival surface.
OS
Supplies: Two clean glass slides, fixative (95% ethyl alcohol), conjunctival scraping spatula, test request form.
CPT Code(s):
8209706
Methodology:
Specimen Required:
CPT Code(s):
2006889
Methodology:
Collection Procedure: Label the slides with the patient's first and last name, date of birth, and specimen source in pencil on the frosted end and
place in a container filled with 95% ethyl alcohol so that the slides are completely covered. Gently scrape the area of abnormality. Remove one of
the slides from the fixative. Quickly and evenly smear the collected material on one of the glass slides. Immediately re-immerse the slide in
fixative. Repeat the process with the second slide, if necessary, for better diagnostic yield. Submit the specimen and the completed request form to
the Cytopathology Laboratory.
Unacceptable Conditions: Refer to the Specimen Rejection in the Specimen Transport Guide.
88160
Cytology, Fine Needle Aspirate
FA
Microscopy
Collect: Refer to Cytology, Fine Needle Aspiration Collection for specific collection and transportation guidelines.
88173 This CPT code may also be reported in conjunction with aspiration of the specimen (10021) and/or evaluation of fine needle aspirate,
immediate cytohistologic study to determine adequacy for diagnosis (88172, 88177). Additional CPT codes may be reported depending on the
preparation methods, such as: 88305 or 88342.
Cytology, Fine Needle Aspirate with Reflex to BRAF V600E Mutation Detection by Allele-Specific PCR, Fine
FR REQUEST
Needle Aspirate
Microscopy/Polymerase Chain Reaction
For superficial aspiration, a clean technique suffices for cleansing of the skin. Local anesthetic may or may not be needed.
If more than two or three passes are anticipated, anesthetic is recommended. However, do not contaminate the lesion with a large volume of
anesthetic. Make passes so as to not affect the ability to palpate and localize the lesion. For deep aspiration, sterile technique is required and local
anesthetic is usually needed.
Use good aspiration technique and appropriate processing of the aspirate to ensure an adequate specimen.
Specimen Required: Collect: FNA specimen, include source and completed Cytology Test Request form.
Specimen Preparation: Specimen Required: Slides with air-dried smear or air-dried and Diff-Quick stained smear. Specimen should be
adequately cellular for cytologic evaluation and obtained from an appropriately performed FNA. Specimen must contain enough material for the
cytopathologist to determine if a mass lesion has been sampled.
Supplies: 10 mL syringe or syringe pistol (optional) and 23 to 27 gauge needle of appropriate length. Multiple single-end-frosted glass for
preparation of direct smears. Fixative for needle rinse (e.g., CytoRich Red, CytoLyt, Saccomanno, etc.).
Preparation of Direct Smears
Before performing the FNA, prepare slides. Use a pencil to label each slide with the patient's first and last name, date of birth, and specimen
source. After collection, carefully transfer the aspirate to the prepared slides using a method appropriate to the nature of the aspirate. If the aspirate
is abundant and fluid, gently express onto the slide. Gentle expression allows for better control of the smear and provides the greatest number of
slides per FNA pass. If the aspirate is scant or is more viscous or solid, appropriate force may be needed to express the aspirate. Excessive force
can result in fewer slides per FNA pass if the aspirate splatters off the slide during expression, and additional FNA passes may be needed if more
studies are required.
Aspirate must be smeared after application to the slide. The simplest procedure is to oppose a second glass slide onto the first, allowing the
material to provide surface tension between the two slides. Then, gently and quickly pull the two slides apart in a horizontal, sliding motion to
distribute the material in a thin film over both slides. Immediately air dry.
Page | 185
The smears should be: air-dried for Diff-Quik staining (delineate with an "A" on the frosted end of the slide).
If aspirate remains in the needle, use to, prepare additional smears or rinse needle into a tube containing fixative or a physiologic solution such as
normal saline, or RPMI.
CPT Code(s):
Submit the specimen (smears and aspirate rinsed into solution) to the ARUP Cytopathology Laboratory along with a completed Cytology test
request form. If transport of specimen in fluid will be delayed more than 24 hours, submit in fixative. If transport time of fluid specimen will be
less than 24 hours, or fixative is not available, keep refrigerated or on wet ice until transport to the lab.
Unacceptable Conditions: Specimens received without an air dried slide or Diff-Quik smear slide. Frozen specimens.
Stability: Needle rinse unfixed. Ambient: Unacceptable; Refrigerated: 24 hours; Frozen: Unacceptable
Needle rinse in fixative. Ambient: Unacceptable; Refrigerated: 1 week; Frozen: Unacceptable
Air-dried smear or Diff-Quik stained smear. Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable
88173 This CPT code may also be reported in conjunction with aspiration of the specimen (10021) and/or evaluation of fine needle aspirate,
immediate cytohistologic study to determine adequacy for diagnosis (88172, 88177). Additional CPT codes may be reported depending on the
preparation methods, such as: 88305 or 88342 if reflexed, add 88381 Microdissection; 83907 Lysis; 83898 x2 Amplification; 83896 Nucleic acid
probe; 83912 Interpretation and report. Additional CPT code modifiers may be required for procedures performed to test oncologic or inherited
disorders.
8209709
Methodology:
Specimen Required:
CPT Code(s):
Cytology, Gastrointestinal
Microscopy
Collect: Refer to Cytology, Gastrointestinal Specimen Collection specific collection and transportation guidelines.
88108 Concentration and interpretation, 88112 Selective cellular enhancement with interpretation and/or 88106 Cytopathology, filter.
GI
8209710
Methodology:
Specimen Required:
CPT Code(s):
Cytology, Oral
GO
Microscopy
Collect: Refer to Cytology, Oral Scraping or Brushing Specimen Collection for specific collection and transportation guidelines.
Depending on collection method: 88108 Concentration and interpretation or 88112 Selective cellular enhancement with interpretation or 88104
Smears with interpretation. Additional CPT codes may apply if special studies are required.
2000624
Methodology:
Cytology, Pap Smear
GG REQUEST
Microscopy
1. In premenopausal patients, obtain specimens during the second half of the menstrual period to avoid contamination by
obscuring blood.
2. Instruct the patient not to douche or engage in sexual intercourse within 24 hours of the procedure.
Specimen Required: Collect: (See below for specific instructions)
1. Label the slide(s) with the patient's first and last name, date of birth, and specimen source directly on the frosted end of the glass, in pencil,
before beginning the procedure. THE LABORATORY WILL NOT ACCEPT UNLABELED SLIDES. Note that a PAP smear folder labeled with
the patient's name is not adequate for patient identification. The patient information must appear on the slide.
2. Obtain all specimens prior to bimanual examination.
3. Place the patient in the lithotomy position. Using an unlubricated vaginal speculum (saline may be used as a lubricant) visualize the cervix as
fully as possible.
4. After collection and proper fixation of specific specimens as outlined below, place slide(s) in a cardboard slide folder and submit to the
Cytopathology Laboratory, with the clinical information.
Specimen Preparation: Routine Cervical/Endocervical (Pap) Smear (1 slide)*
Specimens Required: Unstained cervical or cervical/endocervical slides.
Supplies: Vaginal speculum, plastic extended-tip spatula, cytobrush***, fixative** (spray fixative or bottle of 95 percent ethyl alcohol), clean
glass slide (single-end frosted) and a black lead lab pencil.
Collection Procedure: Label one slide with the patient's first and last name, date of birth, and specimen source (prior to obtaining the specimen).
Obtain specimen prior to bimanual examination. Use an unlubricated speculum (saline or warm water may be used). After visualization of the
cervix is accomplished insert the cytobrush*** into the endocervical canal and rotate half a turn. Withdraw the cytobrush and spread the collected
material quickly and evenly onto the half of the slide opposite the frosted end. The endocervical mucus will prevent air-drying during collection of
the subsequent cervical component. Using the extended-tip spatula, scrape material with the spatula from the whole circumference of the cervix.
Withdraw the spatula and spread the collected material quickly and evenly onto the half of the slide adjacent to the frosted end. Fix immediately
(drop slide into fixative or spray with fixative, holding the spray bottle approximately 8 to 12 inches from the slide). Complete the Cytology test
request form as indicated, including relevant clinical information. Submit the specimen to the Cytopathology Laboratory.
Routine Vaginal Smear - 1 or More Slides
Indications: Can be used in conjunction with routine cervical/endocervical smears in individuals with a uterus, or alone in hysterectomized
patients.
Specimen Required: Lateral vaginal wall smear or smear of sample from a clinically concerning area.
Supplies:Vaginal speculum, one or more plastic cervical spatulas, fixative** (spray fixative or 95% ethyl alcohol), one or more clean glass slides
(single-end frosted) and a black lab pencil.
Collection Procedure: If only a routine lateral vaginal wall sample will be obtained, label one slide with the patient's first and last name, date of
birth, and specimen source. If vaginal sample will be obtained in conjunction with a cervical and endocervical component, make sure that the
slides are also appropriately labeled according to site. If smears from separate vaginal areas are also to be obtained, label the sites accordingly as
to specific site (e.g., left lateral vaginal wall, posterior vaginal wall, etc.). Obtain specimens prior to bimanual evaluation. Use an unlubricated
speculum (saline or warm water may be used). Scrape the desired region of the vaginal mucosa with the spatula. Withdraw the spatula and spread
the material quickly and evenly onto the glass slide (if cervical/endocervical smears are also obtained, or smears from other areas of the vagina are
obtained, make certain that each smear is performed on the correspondingly labeled slide). Fix immediately (drop slide into fixative or spray with
fixative, holding the spray bottle approximately 8 to 12 inches from the slide). Scrape additional areas of the vagina that appear abnormal and
spread and fix as above. Submit the specimen to the Cytopathology Laboratory with relevant clinical history.
Routine Cervical/Endocervical (PAP) Smear (2 or More Slides)*
Specimens Required: Unstained cervical or endocervical slides.
Supplies: Vaginal speculum, plastic extended-tip spatula, cytobrush***, fixative** (spray fixative or bottle of 95% ethyl alcohol), two clean glass
slides (single end frosted) and a black lead lab pencil.
Page | 186
Collection Specimen: Label two slides with the patient's first and last name, date of birth, and specimen source (prior to obtaining the specimen).
Obtain specimens prior to bimanual examination. Use an unlubricated speculum (saline or warm water may be used). After visualization of the
cervix is accomplished, scrape material with the spatula from the whole circumference of the cervix. Withdraw the spatula and spread the
collected material quickly and evenly onto the glass slide. Fix immediately (drop slide into fixative or spray with fixative, holding the spray bottle
approximately 8 to 12 inches from the slide). Insert the cytobrush*** into the endocervical canal and rotate half a turn. Withdraw the cytobrush
and spread the collected material quickly and evenly onto the second slide. Fix immediately (drop slide into fixative or spray with fixative,
holding the spray bottle approximately 8 to 12 inches from the slide). Submit the specimen to the Cytopathology Laboratory with relevant clinical
history.
Vaginal Smear, DES Exposure - 2 or more slides
Indications: Evaluation of potential changes associated with in utero DES exposure.
Specimens Required: Lateral vaginal wall sample, cervical sample, endocervical sample.
Supplies: Vaginal speculum, one or more cervical spatulas, one extended-tip spatula, cytobrush***, fixative** (spray fixative or 95% ethyl
alcohol), two or more clean glass slides (single end frosted), black lead lab pencil, and test request form as indicated.
Collection Procedure: Label two or more slides with patient's first and last name, date of birth, and specimen source. Label one slide "C" and one
"LVW." Label others as necessary (see below). Obtain specimens prior to bimanual examination. Use an unlubricated speculum (saline or warm
water may be used). After visualization of the upper 1/3 of the vagina is accomplished, with the spatula scrape the upper 1/3 of either lateral
vaginal wall. Withdraw the spatula and spread the material quickly and evenly onto the slide clearly marked "LVW." Fix immediately (drop slide
into fixative or spray with fixative, holding the spray bottle approximately 8 to 12 inches from the slide). Scrape additional areas of the vagina that
appear abnormal. Label slides accordingly (prior to sampling) and spread and fix as above. Obtain routine cervical and endocervical specimens as
outlined in the respective procedures. These smears should be collected on the slide labeled "C." Submit the specimen to the Cytopathology
Laboratory with relevant clinical history.
CPT Code(s):
8209702
Methodology:
Specimen Required:
CPT Code(s):
* Procedures for collection of the cervical and endocervical components on either one or two slides are provided.
**Most hair sprays no longer contain adequate amounts of alcohol for appropriate fixation.
***Endocervical sampling devices other than a cytobrush may be used. Refer to specific specimen collection procedures provided with these
devices for more information.
Storage/Transport Temperature: Ambient
Stability: Indefinite
CPT codes vary based on testing performed.
Cytology, Pulmonary
CP
Microscopy
Collect: Refer to Cytology, Pulmonary Specimen Collection for specific collection and transportation guidelines.
Depending on methodology: 88112 Selective cellular enhancement with interpretation or 88108 Concentration and interpretation or 88104 Smears
with interpretation or 88106 Cytopathology, filter. Additional CPT codes may apply if special studies are required.
8209712
Methodology:
Cytology, Skin Scraping
Microscopy
Indications: Detection and characterization of inflammatory/infectious processes of the skin, especially herpetic
infections (Tzanck smear).
Specimen Required: Collect: Direct smear of material collected from a skin lesion, usually a vesicle.
SS
Supplies: Two (or more) clean glass slides (fully frosted), fixative (95% ethyl alcohol), skin scraping spatula, test request form.
CPT Code(s):
place in a container filled with 95% ethyl alcohol so the slides are completely covered. Gently scrape the area of abnormality. If the abnormality is
a vesicle, remove the covering and scrape both at the base of the vesicle and around the rim. Remove one of the slides from the fixative. Quickly
and evenly smear the collected material on one of the glass slides. Immediately re-immerse the slide in fixative. Repeat the process with the
second slide, if necessary, for better diagnostic yield. Repeat the process for additional areas if necessary. After collection, leave the slides in the
95% alcohol for 10 minutes and then air dry. Submit the specimen and the completed request form to the Cytopathology Laboratory.
88160
8100400
Cytology, SurePath™ Liquid-Based Pap Test (AutoCyte PREP™ System)
GA REPORT
Methodology:
Microscopy
Specimen Required: Collect: Refer to Cytology, SurePath™ Liquid-Based Pap Test (AutoCyte PREP™ System) Specimen Collection for collection guidelines.
CPT Code(s):
8100214
This test requires a SurePath™ special collection kit that is available by contacting ARUP Client Services at (800) 522-2787.
Unacceptable Conditions: Specimens not collected in a SurePath™ special collection kit provided by ARUP. Expired SurePath™ vials or vials
received without the collection devices will not be processed. Refer to Specimen Rejection in the Specimen Transport Guide.
Stability: Ambient: 1 month; Refrigerated: 1 month; Frozen: Unacceptable
Refer to the Cytopathology section in front of this User's Guide.
Cytology, SurePath™ Liquid-Based Pap Test (AutoCyte PREP™ System) with Reflex to Human Papillomavirus
GR REPORT
(HPV) DNA Probe, High Risk
Methodology:
Microscopy/Nucleic Acid Probe
Specimen Required: Collect: Refer to Cytology, SurePath™ Liquid-Based Pap Test (AutoCyte PREP™ System) Specimen Collection for collection guidelines.
Remarks: This test includes a Cytology, SurePath™Liquid-Based Pap Test (AutoCyte PREP™ System) (ARUP test code 8100400) and a Human
Papillomavirus (HPV) DNA Probe, SurePath® (Autocyte™) (ARUP test code 0060744), ONLY if the SurePath™ Liquid-Based Pap Test is
interpreted as atypical squamous cells of undetermined significance (ASC-US).
Unacceptable Conditions: Refer to Unacceptable Conditions for Human Papillomavirus (HPV) DNA Probe, High Risk, SurePath® (Autocyte™)
(ARUP test code 0060744) and Cytology, SurePath™ Liquid-Based Pap Test (AutoCyte PREP™ System) (ARUP test code 8100400).
CPT Code(s):
CPT Codes vary based on testing performed. If reflexed to HPV add 87621 High Risk HPV
Page | 187
2000134
Methodology:
Cytology, SurePath Liquid-Based Pap Test
GA REQUEST
Microscopy
1. For premenopausal patients, obtain specimens during the second half of the menstrual period to avoid contamination by
obscuring blood.
2. Instruct the patient not to douche or engage in sexual intercourse within 24 hours of the procedure
Supplies: This test requires a SurePath collection kit, which includes a preservative fluid collection vial and sampling device(s). Kits may be
ordered separately through ARUP Client Services at (800) 522-2787 or (801) 583-2787. Also required: ARUP Cytology test request form,
permanent marker.
Specimen Required: Collect: 1. Label the vial(s) with the patient's first and last name, date of birth, and specimen source before beginning the procedure.
2. Obtain all specimens prior to bimanual examination.
3. Place the patient in the lithotomy position. Using an unlubricated vaginal speculum (saline may be used as a lubricant) visualize the cervix as
fully as possible.
4. Follow the instructions for the specific collection kit used.
Collection Procedure: Obtain cervical specimen prior to bimanual examination. Use an unlubricated speculum (saline or warm water may be
used). Vaginal discharge or secretion, when present in large amounts, should be removed before obtaining the cervical sample so as not to disturb
the epithelium (i.e., cellulose swab). Small amounts of blood will not interfere with the cytologic evaluation; however, large amounts of blood as
present during menses may interfere with cytologic evaluation because cells may be obscured by blood. Use of liquid-based specimen collection
minimizes the interference from these factors. If testing for sexually transmitted disease is indicated, the cervical cytology sample should be taken
first. After visualization of the cervix is accomplished, collect the sample. Obtain an adequate sampling from the cervix using the Rovers®
Cervex-Brush® or Cervex-Brush® Combi or the Pap Perfect® plastic spatula with the Cytobrush® Plus GT.
ROVERS® CERVEX-BRUSH® Collection (Kit #22216): Device may be referred to as broom. Position the tip of the longer bristles into the
cervical os/endocervical canal. Begin rotating in a clockwise direction (one-quarter to one-half turn). The bristles will begin to stiffen. Continue
rotating in a clockwise direction and gently push towards the cervix until the shorter bristles begin to bend extending over the ectocervix.
Complete five 360-degree rotations. Direction must be consistent. Do not alter or vary the direction of the broom during sampling. Transfer the
entire sample by placing your thumb against the back of the brush pad, and simply disconnect the entire brush from the stem into the preservative
vial. Contraindication: Do not use on pregnant patients after the first 10 weeks of gestation.
PAP PERFECT® PLASTIC SPATULA AND CYTOBRUSH® PLUS GT Collection (Kit #41126): Insert the contoured end of the Pap
Perfect plastic spatula and rotate 360 degrees around the entire exocervix. Disconnect the spatula head and place it in into the vial. Insert the
Cytobrush Plus GT into the endocervix until only the bottom most fibers are exposed at the cervical os. Slowly rotate or turn one half turn in one
direction. To reduce unnecessary bleeding, DO NOT over rotate. Disconnect the brush head and place in the preservative vial. Contraindication:
Do not use on pregnant patients or for endometrial sampling.
ROVERS® CERVEX-BRUSH® COMBI Collection (Kit #45031): Insert central bristles into the endocervical canal. Use gentle pressure on
the cervix until the lateral bristles bend against the ectocervix. Maintain gentle pressure and rotate two times in a clockwise direction by rolling the
stem between the thumb and forefinger. Disconnect the brush head and place in the preservative vial. Contraindication: This device should not
be used during pregnancy.
CPT Code(s):
For all kits, recap the preservative vial and tighten. Record the patient's information and medical history on the ARUP Cytology test request form.
Place the vial and test request form in a specimen bag for transport to the laboratory.
Storage/Transport Temperature: Ambient
Unacceptable Conditions: Specimens not collected in a SurePath collection kit. Expired preservative vials or vials received without the collection
devices.
88174 (automated) or 88175 (automated with manual review) or 88142 (manual screening) or 88143 (manual screening with rescreening) if
reviewed by pathologist 88141
8100211
Cytology, ThinPrep® Pap Test™
GT REPORT
Methodology:
ThinPrep® 2000 System
Specimen Required: Collect: Refer to Cytology, Thin Prep® Pap Test™ Specimen Collection for specific collection guidelines. Discard collection device.
CPT Code(s):
This test requires a ThinPrep® Pap Test™ special collection kit that is by contacting ARUP Client Services at (800) 522-2787.
Remarks: Human Papillomavirus (HPV) DNA Probe testing can be performed on the PreservCyt® Solution vial, refer to Human Papillomavirus
(HPV) DNA Probe, High Risk (ARUP test code 0065999), or Cytology, ThinPrep® Pap with Reflex to Human Papillomavirus (HPV) DNA
Probe, High Risk (ARUP test code 8100212).
Unacceptable Conditions: Specimens not collected in a ThinPrep® Pap Test™ special collection kit or specimens submitted in an expired
collection kit. Refer to Specimen Rejection in the Specimen Transport Guide.
Stability: PreservCyt® Solution preserves cells for up to three weeks refrigerated or room temperature.
CPT codes vary based on testing performed. Refer to the Cytopathology section in front of this User's Guide.
8100212
Cytology, ThinPrep® Pap with Reflex to Human Papillomavirus (HPV) DNA Probe, High Risk
TR REPORT
Methodology:
ThinPrep® 2000 System/Microscopy/Nucleic Acid Probe
Specimen Required: Collect: Refer to Cytology, ThinPrep® Pap Test™ Specimen Collection for collection guidelines.
Remarks: This test includes a Cytology, ThinPrep® Pap Test™(ARUP test code 8100211), and an Human Papillomavirus (HPV) DNA Probe,
High Risk, ThinPrep® (ARUP test code 0060750) ONLY if the ThinPrep® PapTest™ is interpreted as atypical squamous cells of undetermined
significance (ASC-US).
Unacceptable Conditions: Refer to unacceptable conditions for Human Papillomavirus (HPV) DNA Probe, High Risk, ThinPrep® (ARUP test
code 0060750) and Cytology, ThinPrep® PapTest™ (ARUP test code 8100211).
CPT Code(s):
CPT codes vary based on testing performed. If reflexed to HPV add: 87621 High-risk HPV
8209714
Methodology:
Page | 188
Cytology, Tzanck Smear
Microscopy
Indications: Detection and characterization of inflammatory/infectious processes of the skin, especially herpetic
infections.
SZ
Specimen Required: Collect: Direct smear of material collected from a skin lesion, usually a vesicle.
Supplies: Two (or more) clean glass slides fixative (95% ethyl alcohol), skin scraping spatula, and Cytology test request form.
CPT Code(s):
8209704
Methodology:
Specimen Required:
CPT Code(s):
place in a container filled with 95% ethyl alcohol so the slides are completely covered. Gently scrape the area of abnormality. If the abnormality is
a vesicle, remove the covering and scrape both at the base of the vesicle and around the rim. Remove one of the slides from the fixative. Quickly
and evenly smear the collected material on one of the glass slides. Immediately re-immerse the slide in fixative. Repeat the process with the
second slide, if necessary, for better diagnostic yield. Repeat the process for additional areas if necessary. After collection, leave the slides in the
95% alcohol for 10 minutes and then air dry. Submit the specimen and the completed test request form to the Cytopathology Laboratory.
Unacceptable Conditions: Air dried smears. Refer to the Specimen Rejection section Specimen Transport Guide.
88160
Cytology, Urologic
Microscopy
Collect: Refer to Cytology, Urologic Specimen Collection for collection and transport guidelines.
88108 Concentration and interpretation or 88112 Selective cellular enhancement with interpretation and/or 88106 Cytopathology, filter. Additional CPT codes may apply if special studies are required.
CU
8209715
Methodology:
Cytology, Vitreous Fluid
VF
Microscopy
Indications: Detection and characterization of malignant cells in the eye. In cytology, vitreous fluid is most commonly
evaluated to detect and characterize malignancy which may have gained access to the eye. Vitreous fluid specimens require special collection
procedures under the direction of an ophthalmologist. In addition, due to lack of nutrients in this fluid, cells may rapidly degenerate rendering
morphologic evaluation less than optimal if adequate care is not taken.
Specimen Required: Collect: For vitreous fluids, there is no minimum amount, but collect as much as possible.
Supplies: Standard vitreous aspiration equipment. Standard vitreous aspirate collection container for vitreous fluid. Fixative (50% ethyl alcohol).
Collection Procedure: Using standard vitreous collection procedures, collect an appropriate amount of vitreous fluid. In general, morphology of
cells within vitreous fluid can be adequately maintained with prompt refrigeration for 24 hours. Although a fresh specimen is preferred, if a longer
time period between collection and processing is anticipated, the specimen may be preserved by adding an equal volume of 50% ethyl alcohol to
the specimen. Label the specimen with patient's first and last name, date of birth and specimen source. Submit the specimen to the Cytopathology
Laboratory along with the completed Cytology request form.
CPT Code(s):
Note: Specimens submitted for immunocytochemical testing must be submitted fresh. If necessary, on-call personnel can be utilized during the
evenings or on weekends for processing of urgent specimens or those which need to be processed rapidly to avoid degeneration.
Stability: Refrigerated: 72 hours
88108 Concentration and interpretation or 88112 Selective cellular enhancement with interpretation and/or 88106 Cytopathology, filter Additional CPT codes may apply if special studies are required.
0050622
Cytomegalovirus Antibodies, IgG and IgM
CMV PAN
Methodology:
Semi-Quantitative Chemiluminescent Immunoassay
Specimen Required: Collect: Serum separator tube.Also acceptable: Serum from umbilical cord blood
Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) Parallel testing is preferred and convalescent specimens must be
received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute" or "convalescent."
Unacceptable Conditions: Urine. Contaminated, hemolyzed, or heat-inactivated specimens.
CPT Code(s):
86644 CMV IgG; 86645 CMV IgM
0050165
Cytomegalovirus Antibody, IgG
CMV IGG
Methodology:
Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) Acute and convalescent specimens must be labeled as such; parallel
testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as
"acute" or "convalescent." Also acceptable: Serum from umbilical cord blood.
Unacceptable Conditions: Urine. Contaminated, hemolyzed, or heat-inactivated specimens.
CPT Code(s):
86644
0050553
Cytomegalovirus Antibody, IgM
CMV IGM
Methodology:
Semi-Quantitative Chemiluminescent Immunoassay
Specimen Required: Collect: Serum separator tube. Also acceptable: Serum from umbilical cord blood.
Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) Acute and convalescent specimens must be labeled as such; parallel
testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as
"acute" or "convalescent."
Unacceptable Conditions: Urine. Contaminated, heat-inactivated or hemolyzed specimens.
CPT Code(s):
86645
Page | 189
2004760
Cytomegalovirus Antiviral Drug Resistance by Sequencing
CMV RESIST
Methodology:
Specimen Required: Collect: Lavender (EDTA), pink (K2EDTA) or plasma preparation tube.
Specimen Preparation: Separate plasma from cells within 8 hours. Transfer 4 mL plasma to an ARUP Standard Transport Tube. (Min: 2.5 mL)
Remarks: Viral load required.
Unacceptable Conditions: Serum. Heparinized specimens.
CPT Code(s):
83891 Isolation; 83894 Separation; 83898 x5 Amplification; 83904 x5 Sequencing; 83909 Capillary electrophoresis; 83912 Interpretation
0060040
Cytomegalovirus by PCR
CMVPCR
Methodology:
Specimen Required: Collect: Lavender (EDTA), pink (K2EDTA), or serum separator tube. Amniotic fluid, bronchoalveolar lavage (BAL), CSF, ocular fluid, tissue, or
urine.
Specimen Preparation: Separate serum or plasma from cells. Transfer 1 mL plasma, serum, amniotic fluid, BAL, CSF, ocular fluid, or urine to a
sterile container. (Min: 0.5 mL) Tissue: Transfer to a
sterile container and freeze immediately.
Storage/Transport Temperature: Frozen. Submit specimen according to Biological Substance, Category B, shipping guidelines.
Unacceptable Conditions: Whole blood or bone marrow; refer to Cytomegalovirus by PCR, Whole Blood or Bone Marrow (ARUP test code
0060031). Heparinized specimens.
Stability: Tissue: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 3 months
All others: Ambient: 8 hours; Refrigerated: 72 hours; Frozen: 3 months
CPT Code(s):
87496
0060031
Cytomegalovirus by PCR, Whole Blood or Bone Marrow
CMVPCR B
Methodology:
Specimen Required: Collect: Lavender (EDTA), pink (K2EDTA) or bone marrow aspirate in lavender (EDTA) or pink (K2EDTA).
Specimen Preparation: Do not freeze specimens. Transport 1 mL whole blood OR 1 mL bone marrow. (Min: 0.5 mL).
Unacceptable Conditions: Plasma (refer to Cytomegalovirus by PCR, ARUP test code 0060040). Heparinized specimens. Frozen specimens.
CPT Code(s):
87496
2003833
Cytomegalovirus (CMV) by Immunohistochemistry
CMV IHC
Methodology:
CPT Code(s):
88342
2006568
Methodology:
Cytomegalovirus (CMV) CD8 T-Cell Immune Competence, HLA-A1
CMV CD8 A1
Cell Culture/Quantitative Flow Cytometry
Patient must be CMV-seropositive and have one or more of the five major histocompatibility complex (MHC) alleles:
HLA-A1, -A2, -B7, -B8, or -B35.
Specimen Required: Collect: Green (sodium heparin). Collect only one specimen for any combination of five CMV CD8 T-Cell Immune Competence assays ordered.
Patient specimen must be collected within 48 hours of test performance.
Specimen Preparation: Transport 10 mL whole blood (total volume for up to five separate CMV CD8 tests) in original collection tubes. (Min: 7
mL).
Do not refrigerate or freeze. LIVE LYMPHOCYTES REQUIRED.
Unacceptable Conditions: Refrigerated or frozen specimens. Gross hemolysis or gross lipemia. Specimens in transport longer than 48 hours.
CPT Code(s):
88184 - Flow Cytometry, cell surface, cytoplasmic, or nuclear marker, technical component only; first marker
86352 - Cellular functional assessment of allele-specific stimulation
For orders of up to 5 separate HLA alleles (CMV CD8 A1, A2, B7, B8 and/or B35) on the same patient specimen, add the following just once:
88185 x2 - Flow Cytometry, cell surface, cytoplasmic, or nuclear marker, technical component only; each additional marker
86352 - Cellular functional assessment of non-allele-specific stimulation
2006576
Methodology:
Cytomegalovirus (CMV) CD8 T-Cell Immune Competence, HLA-A2
CMV CD8 A2
HLA-A1, -A2, -B7, -B8, or -B35.
mL). Do not refrigerate or freeze. LIVE LYMPHOCYTES REQUIRED.
Page | 190
CPT Code(s):
2006588
Methodology:
Cytomegalovirus (CMV) CD8 T-Cell Immune Competence, HLA-B35
CMV CD8B35
HLA-A1, -A2, -B7, -B8, or -B35.
CPT Code(s):
2006580
Methodology:
CMV CD8 B7
HLA-A1, -A2, -B7, -B8, or -B35.
CPT Code(s):
2006584
Methodology:
CMV CD8 B8
HLA-A1, -A2, -B7, -B8, or -B35.
mL).
Do not refrigerate or freeze. LIVE LYMPHOCYTES REQUIRED.
CPT Code(s):
For orders of up to 5 separate HLA alleles (CMV CD8 -A1, -A2, -B7, -B8 and/or -B35) on the same patient specimen, add the following just once:
2003044
Cytomegalovirus IgG Avidity (AviDx™), ELISA
Methodology:
Enzyme-Linked Immunosorbent Assay
Stability: Ambient: 5 days; Refrigerated: 2 weeks; Frozen: 1 month
CPT Code(s):
86644x2
0051813
Cytomegalovirus, Quantitative PCR
Methodology:
Quantitative Polymerase Chain Reaction
Specimen Preparation: Separate plasma from cells. Transfer 1 mL plasma to a sterile container. (Min: 0.5 mL).
Page | 191
CMV AVID
CMV QNT
CPT Code(s):
Stability: Ambient: 24 hours; Refrigerated: 5 days; Frozen: 1 year
87497
2006966
Cytomegalovirus, Quantitative PCR with Reflex to Drug Resistance Testing by Sequencing
CMV QNT GR
Methodology:
Quantitative Polymerase Chain Reaction/Sequencing
Specimen Preparation: Separate plasma from cells. Transfer 4 mL plasma to a sterile container. (Min: 2.5 mL)
Stability: Ambient: 8 hours; Refrigerated: 72 hours; Frozen: 1 year
CPT Code(s):
87497 Cytomegalovirus Quantitative PCR; if reflexed, add 83891 Isolation; 83894 Separation; 83898 x5 Amplification; 83904 x5 Sequencing;
83909 Capillary electrophoresis; 83912 Interpretation
0065004
Cytomegalovirus Rapid Culture
V CMVC
Methodology:
Cell Culture/Immunofluorescence
Specimen Required: Collect: Lavender (EDTA) or pink (K2EDTA). OR bronchoalveolar lavage (BAL), throat swab, tissue, or urine.
Specimen Preparation: Blood: Transport 5 mL whole blood. (Min: 1 mL)
Fluid specimen: Transfer specimen to a sterile container. Transfer 2 mL fluid to a sterile container. (Min: 0.5 mL). Also acceptable: Transfer to
viral transport media (ARUP supply #12884). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at
(800) 522-2787.
Swab or tissue: Place in viral transport media.
Place each specimen in an individually sealed bag.
Unacceptable Conditions: CSF, rectal swab, or stool. Whole blood in viral transport media. Calcium alginate, dry, or wood swabs.
Stability: Ambient: 2 hours; Refrigerated: 72 hours; Frozen: Unacceptable.
CPT Code(s):
87254 Shell vial
0030057
D-Dimer
D-DI
Methodology:
Immunoturbidimetry
Specimen Required: Collect: Light blue (sodium citrate). Refer to Specimen Handling at aruplab.com for hemostasis/thrombosis specimen handling guidelines.
Specimen Preparation: Transfer 2 mL platelet poor plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Stability: After separation from cells: Ambient: 8 hours; Refrigerated: 8 hours; Frozen: 1 month
CPT Code(s):
85379
2003857
D2-40 by Immunohistochemistry
D240 IHC
Methodology:
CPT Code(s):
88342
0091356
Dantrolene, Serum or Plasma
DANTROLENE
Methodology:
Spectrofluorometry
Specimen Preparation: Protect from light. Transfer 2 mL serum or plasma to an ARUP Amber Transport Tube. (Min: 0.3 mL)
Unacceptable Conditions: Separator tubes. Specimens not protected from light.
CPT Code(s):
80299
0091576
Darvocet, Serum or Plasma
Methodology:
Quantitative Gas Chromatography/Mass Spectrometry/High Performance Liquid Chromatography
CPT Code(s):
80299; 82003
0091589
Darvocet, Urine
Methodology:
Quantitative Gas Chromatography/Mass Spectrometry/High Performance Liquid Chromatography
CPT Code(s):
80299; 82003
Page | 192
DARVOCET S
DARVO URN
2007223
DDIT3 (CHOP) (12q13) Gene Rearrangement by FISH
CHOP FISH
Methodology:
micron slides. (Min: 3 slides) Protect paraffin block from excessive heat. Transport block(s) and/or slide(s) in a tissue transport kit (ARUP supply
#47808) available online through eSupply using ARUP Connect™or contact ARUP Client Services at (800) 522-2787.
Storage/Transport Temperature: Room temperature. Also acceptable: Refrigerated. Ship in cooled container during summer months.
Unacceptable Conditions: Frozen specimens. Specimens fixed or processed in alternative fixatives (alcohol, Prefer®) or heavy metal fixatives (B4 or B-5). No tumor in tissue. Decalcified specimens.
CPT Code(s):
88368 x2
Deamidated Gliadin Peptide (DGP) Antibodies, IgA and IgG
0051358
Methodology:
Specimen Preparation: Separate serum from cells ASAP or within 2 hours of collection. Transport 1 mL serum. (Min: 0.3 mL)
Unacceptable Conditions: Plasma or other body fluids. Contaminated, hemolyzed, or grossly lipemic specimens.
CPT Code(s):
83516 x2
GLIAD PAN
0051357
Deamidated Gliadin Peptide (DGP) Antibody, IgA
GLIADPEP A
Methodology:
Specimen Preparation: Separate serum from cells ASAP or within 2 hours of collection. Transport 0.5 mL serum. (Min: 0.3 mL)
Unacceptable Conditions: Plasma or other body fluids. Contaminated, hemolyzed, grossly icteric, or grossly lipemic specimens.
CPT Code(s):
83516
0051359
Deamidated Gliadin Peptide (DGP) Antibody, IgG
GLIADPEP G
Methodology:
Specimen Preparation: Separate serum from cells ASAP or within 2 hours of collection. Transport 0.5 mL serum. (Min: 0.3 mL)
Unacceptable Conditions: Plasma or other body fluids. Contaminated, hemolyzed, grossly icteric, or grossly lipemic specimens.
CPT Code(s):
83516
2003326
deCODE ProstateCancer™ (Genetic Risk Assessment)
PROST CAN
Methodology:
Polymerase Chain Reaction/Fluorescent Primer/Nucleic Acid Probe
Specimen Required: Collect: All specimens must be collected using the Buccal DNA Collector Kit (ARUP Supply #47080). Available online through eSupply using
ARUP Connector contact ARUP Client Services at (800) 522-2787.
1. Use gloves to protect the specimen from contamination.
2. Remove the Buccal DNA Collector from the pouch, holding the handle at the base.
3. Move slider cover back if necessary to fully expose the collection paper. Press the collection paper flat against cheek and drag across at least 7
times.
Specimen Preparation: Push cover forward towards the tip of the collector, covering the collection paper. Transport 2 buccal swabs.
Unacceptable Conditions: This test was validated for patients of European Caucasian descent only; specimens from patients of other ethnicities
will be rejected. Swabs other than those provided in the Buccal DNA Collector Kit.
CPT Code(s):
83891 Isolation; 83892 Enzymatic digestion; 83898 x25 Amplification; 83896 x25 Nucleic acid probes; 83914 x25 Extension; 83912
2001640
Methodology:
Dehydroepiandrosterone, Serum or Plasma
DHEA TMS
Specimen Required: Collect: Serum separator tube or green (sodium or lithium heparin). Also acceptable: Lavender (EDTA).
CPT Code(s):
82626
0070040
Dehydroepiandrosterone Sulfate, Serum
DHEAS
Methodology:
(K2EDTA).
CPT Code(s):
82627
Page | 193
0093096
Dengue Fever Virus Antibodies, IgG & IgM
DENGUE AB
Methodology:
specimens. Mark specimens plainly as "acute or convalescent."
Unacceptable Conditions: Contaminated, heat-inactivated, hemolyzed, severely lipemic specimens.
CPT Code(s):
86790 Dengue fever IgG; 86790 Dengue fever IgM
0093097
Dengue Fever Virus Antibody, IgG
DEN G
Methodology:
specimens. Mark specimens plainly as "acute or convalescent."
CPT Code(s):
86790
0093098
Dengue Fever Virus Antibody, IgM
DEN M
Methodology:
specimens. Mark specimen plainly as "acute or convalescent."
CPT Code(s):
86790
2007206
Deoxycorticosterone (DOC), Serum
DOC SER
Methodology:
Storage/Transport Temperature: Frozen. Also acceptable: Refrigerated.
CPT Code(s):
82633
0092331
11-Deoxycortisol Quantitative by LC-MS/MS, Serum or Plasma
DEOXYCORT
Methodology:
Specimen Required: Collect: Serum separator tube. Also acceptable: Plain red, lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin).
CPT Code(s):
82634
0070212
Methodology:
Deoxypyridinoline Crosslinks, Urine
DPD
First-morning void.
Specimen Preparation: Transfer 3.5 mL aliquot from a well-mixed, first-morning urine to an ARUP Standard Transport Tube. (Min: 0.5 mL)
CPT Code(s):
82523
0081312
Des-gamma-carboxy Prothrombin
DCP
Methodology:
Quantitative Liquid Chromatography/Immunoassay
Specimen Preparation: Allow specimen to clot completely at room temperature. Separate from cells ASAP or within 2 hours of collection.
Stability: After separation from cells: Ambient: 8 hours; Refrigerated: 1 week; Frozen: 3 months (avoid repeated freeze/thaw cycles)
CPT Code(s):
83951
0090072
Methodology:
Desipramine
DESIP HPLC
If imipramine has been administered, order Imipramine and Desipramine (ARUP test code 0090157).
Page | 194
CPT Code(s):
80160
2003863
Desmin by Immunohistochemistry
DESMIN IHC
Methodology:
CPT Code(s):
88342
2003248
Methodology:
Dexamethasone, Serum or Plasma by LC-MS/MS
DEXA TMS
Liquid Chromatography-Tandem Mass Spectrometry
Specimen Required: Collect: Serum separator tube, lavender (EDTA), pink (K2EDTA), or green (sodium heparin).
mL)
CPT Code(s):
80299
2006236
Diamond-Blackfan Anemia (RPL11) Sequencing
RPL11 FGS
Methodology:
Sequencing
CPT Code(s):
83891 Isolation; 83898 x12 Amplification; 83894 x6 Gel separation; 83904 x12 Sequencing; 83892 x2 Digestion; 83912 Interpretation and report.
2006234
Diamond-Blackfan Anemia (RPL5) Sequencing
RPL5 FGS
Methodology:
Sequencing
CPT Code(s):
83891 Isolation; 83898 x26 Amplification; 83894 x13 Gel separation; 83904 x26 Sequencing; 83892 x2 Digestion; 83912 Interpretation and
report.
2006238
Diamond-Blackfan Anemia (RPS19) Sequencing
RPS19 FGS
Methodology:
Sequencing
CPT Code(s):
83891 Isolation, 83898 x8 Amplification; 83894 x8 Gel separation; 83904 x8 Sequencing; 83892 x2 Digestion; 83912 Interpretation and report.
0090076
Diazepam and Nordiazepam
DIAZ
Methodology:
CPT Code(s):
80154 x2
0091471
Diazoxide, Urine
Methodology:
Stability: Undetermined; Refrigerated: Undetermined; Frozen: Undetermined
CPT Code(s):
80299
Page | 195
DIAZOX UR
0091324
2,4-Dichlorophenoxyacetic Acid, Serum or Plasma
Methodology:
Gas Chromatography
Specimen Preparation: Transfer 4 mL serum or plasma to an ARUP Standard Transport Tube.
CPT Code(s):
83921
0091379
2,4-Dichlorophenoxyacetic Acid, Urine
Methodology:
Gas Chromatography
Specimen Preparation: Transfer 4 mL urine to an ARUP Standard Transport Tube.
Stability: Ambient: Undetermined; Refrigerated: Undetermined; Frozen: Undetermined.
CPT Code(s):
83921
2-4-DICHL
2-4-D U
0090085
Digitoxin
DIGT
Methodology:
Quantitative CEDIA Immunoassay
Stability: After separation from cells: Ambient: 5 days; Refrigerated: 5 days; Frozen: 2 months
CPT Code(s):
80299
0090080
Methodology:
Digoxin
DIG
Immunoassay
Collect specimen 8-12 hours (no earlier than 6 hours) after administration of oral dose.
Specimen Required: Collect: Plain red. Also acceptable: Green (sodium or lithium heparin).
Specimen Preparation: Remove serum or plasma from cells within 2 hours of collection. Transfer 4 mL serum or plasma to an ARUP Standard
Remarks: Refrigerated.
Unacceptable Conditions: Specimens collected in sodium fluoride, potassium oxalate or separator tubes. Hemolyzed specimens.
Stability: After separation from cells: Ambient: 8 hours; Refrigerated: 48 hours; Frozen: 1 week
CPT Code(s):
80162
2002349
Methodology:
5-a-Dihydrotestosterone by Tandem Mass Spectrometry, Serum
DHT TMS
Unacceptable Conditions: Hemolyzed or lipemic specimens.
CPT Code(s):
82651
2006226
Dilated Cardiomyopathy (DCM)/Left Ventricular Noncompaction (LVNC) Panel, 27 Genes
DCM PANEL
Methodology:
CPT Code(s):
0091348
Diltiazem, Serum or Plasma
Methodology:
Gas Chromatography
Specimen Required: Collect: Lavender (EDTA) or plain red.
Stability: Ambient: 8 days; Refrigerated: 8 days; Frozen: 1 year
CPT Code(s):
80299
DILTIAZE
0030461
Dilute Russell Viper Venom Time (dRVVT) with Reflex to dRVVT 1:1 Mix & Confirmation
DRV CONF
Methodology:
Clotting
Unacceptable Conditions: Serum. Hemolyzed specimens.
CPT Code(s):
85613 dRVVT; if reflexed add 85613 dRVVT 1:1 mix; and 85613 dRVVT confirmation
Page | 196
0091308
Diphenhydramine Quantitation, Serum or Plasma
Methodology:
Gas Chromatography
Stability: Ambient: 2 weeks; Refrigerated: 25 days; Frozen: 18 months
CPT Code(s):
80299
0091219
Diphenhydramine, Urine
Methodology:
Gas Chromatography
Stability: Ambient: 2 weeks; Refrigerated: 25 days; Frozen: 18 months
CPT Code(s):
80299
DIPHENHYDR
DIPHEN UR
0050595
Diphtheria & Tetanus Antibodies, IgG
D/T
Methodology:
Specimen Required: Collect: Serum separator tube. "Pre" and "post" vaccination specimens should be submitted for testing. "Post" specimen should be drawn 30 days
after immunization.
Tube. (Min: 0.15 mL) Mark specimens clearly as "Pre-Vaccine" or "Post-Vaccine". If shipped separately, "Post" specimen must be received
within 60 days of "Pre" specimen.
Unacceptable Conditions: Plasma or other body fluids.
CPT Code(s):
86317 Diphtheria; 86317 Tetanus
0050210
Diphtheria Antibody, IgG
DIP
Methodology:
Specimen Required: Collect: Serum separator tube. "Pre" and "post" vaccination specimens should be submitted together for testing. "Post" specimen should be drawn
30 days after immunization.
Tube. (Min: 0.15 mL) Mark specimens clearly as "Pre-Vaccine" or "Post-Vaccine". If shipped separately, "Post" specimen must be received
within 60 days of "Pre" specimen.
Unacceptable Conditions: Plasma or other body fluids.
Stability: After separation from the cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
CPT Code(s):
86317
0050779
Diphtheria, Tetanus, and H. Influenzae b Antibodies, IgG
DTH
Methodology:
Specimen Preparation: Transfer 1.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.45 mL) Acute and convalescent specimens must be
labeled as such. Clearly mark specimens as "Pre-Vaccine" or "Post-Vaccine". Parallel testing is preferred and convalescent specimens must

2013 LABORATORY TEST DIRECTORY

Transcription

Similar documents

segovia`s Distribution inc.

Torontech_Compression Flexometer TTCF Series

Cym canaliculatum - Cymbidium Orchid Club of Western Australia

Tacca integrifolia_White Bat Plant

superanal

View PDF - Natural History Museum of Los Angeles

THE ARSEN MIMETITE: a lead Arsenate species: (+) char radical

GWD860W-4 GWD860BLS-4 Water Dispenser

(peripheral blood or bone marrow aspirate

VS120 - Olympus