April 1, 2009 - mArch 31, 2010 AnnuAl report
Transcription
April 1, 2009 - mArch 31, 2010 AnnuAl report
April 1, 2009 - march 31, 2010 annual report Contents AWARENESS SUPPORT research 01 Table of Contents 02 President & CEO’s Message 03 Chair’s Message 04 SMAC Chair’s Message 05 Prostate Cancer Canada Network 06 Research 08 Guidelines for Early Detection 14 Donors 17 Board of Directors / SMAC 18 Condensed Financial Statements 01 prostatecancer.ca President’s Message Leadership. Not the leadership of an individual, but of an organization. In the fight against prostate cancer, the goal of Prostate Cancer Canada has been to assume the leadership position and stand up for survivors and their families across Canada, while continuing to raise awareness and fund vital research which will someday lead to a cure. This is why we take a strong stand in support of early detection through the PSA test. We know there is controversy surrounding the PSA test, and stakeholders around the world are debating its merits. While we listen very closely to the opinions of doctors, researchers, scientists, and other prostate cancer experts, the people we trust the most are the prostate cancer survivors, those who have been directly impacted. Over and over again, survivors tell us the same thing: the PSA test was the red flag that alerted them (and their doctor) to a potential problem. Over and over again, we have heard them say, “the PSA test saved my life.” At Prostate Cancer Canada we believe it is important for leaders to rise above debates on issues like this. 02 “We believe the best approach is to inform and educate Canadians on all aspects of a controversy, and so, we present both sides of the story, while also clearly articulating our position.” Chair’s Message The past 12 months have been full of continuing success for Prostate Cancer Canada. Led by a very strong, engaged Board of Directors, composed of leaders from the business and healthcare communities, and an experienced, dedicated staff committed to our cause, we are quickly becoming known as the Canadian leader in the battle against the most common cancer to afflict Canadian men. As a prostate cancer survivor, I know firsthand the challenges faced by men and their loved ones following a prostate cancer diagnosis. Because of this, I remain as determined as ever to support Prostate Cancer Canada as it unites Canadians from coast to coast, raising needed funds for research, education, support and awareness. I will be stepping down as Chair of the PCC Board of Directors in September 2010. I have had the privilege of serving as Chair for the past 3 years, seeing the organization through much change. While I will remain on the Board for the foreseeable future as past Chair, it is time to leave the leadership role, and I do so with gratitude to my fellow directors, staff and all of the volunteers who have played a part in our success story. The next 12 months promise to be exciting, invigorating and full of promise for a better future. I look forward to seeing Prostate Cancer Canada become more prominent in the lives of Canadians, as we work diligently to raise awareness for this disease. We look forward to the challenges ahead. 03 This annual report is unique, in that in addition to subjects traditionally found in a periodical such as this, we also include a section on the PSA test . We hope you find it informative. Thanks to our staff, Board of Directors, and to all those who have worn the tie or scarf, donated to our organization, and/or volunteered precious time to join the fight. We are privileged to work for you and with you. Steve Jones President & CEO “As a prostate cancer survivor, I know first hand the challenges faced by men and their loved ones following a prostate cancer diagnosis.” Lee Watchorn Chair, Board of Directors prostatecancer.ca A message from the Chair of the Scientific & Medical Advisory Committee Prostate cancer canada network This has been an exciting time for Prostate Cancer Canada. Being the only national organization that is solely committed to the elimination of prostate cancer through research, education, support, and awareness, we find ourselves closer to reaching our vision of being a global leader in the fight against this disease. With the merger of the Canadian Prostate Cancer Network (CPCN) with Prostate Cancer Canada, and its revitalization under the new name, Prostate Cancer Canada Network (PCCN), we have crossed the threshold into a new era of support for the hundreds of thousands of Canadian men currently living with prostate cancer and the 24,600 that will be diagnosed this year. This year we reached new heights as we offered the largest amount of funding for grants and awards since the inception of the PCC research program. Over $2.4 million was awarded to 19 promising researchers, whose proposals demonstrated the highest scientific merit and displayed the most relevance to PCC’s mandate of aiming to achieve the greatest impact on the prevention, detection and treatment of prostate cancer. We recently embarked upon a ground-breaking initiative, where PCC has taken the lead in an International Cancer Genome Consortium (ICGC). This study is expected to generate high quality data which will meet global standards for genome sequencing projects and will be shared with researchers worldwide. It is considered to be the most important prostate cancer project in history, for the following reasons: 04 1. It will involve testing bio-banked material from prostate cancer patients around the world which can assist in the identification of genetic alterations that are related to aggressive cancer and treatment failures. 2. Information may be used to develop improved diagnostic methods which could assist with determining the types of cancers that require immediate treatment as well as those that can be monitored. 3. New therapies can be created to treat prostate cancer which is resistant to existing treatments. 4. It may lead to improvements in screening procedures and treatment strategies. “While we look forward to continued advancements at Prostate Cancer Canada, it is with unwavering dedication that we remain committed to improving the lives of men who are affected by prostate cancer worldwide.” Our network of independent support groups blend well with PCC’s national strategies, putting a local face in the media and with the general public. PCCN affiliated groups are encouraged to ‘work local, think national’ because as one voice on the national stage we are more powerful and have increased visibility when it comes to local efforts and activities. Group work includes monthly meetings, one-on-one hospital visits, newsletters, awareness sessions, and presentations at health fairs and service clubs like Rotary, Gyro, and Lions. “Our local groups enjoy excellent relationships with medical professionals in their community and give freely of their time to help educate and consult.” When media calls, knowledgeable survivors are ready to tell their personal stories. Support groups put a local face to this, the most common cancer to afflict Canadian men. Groups also participate in PCC events such as Wake Up Call Breakfasts, Safeway Father’s Day Walk/Run and Movember. 05 Although prostate cancer is an exclusively male disease, it often has a profound impact on the family unit. Many groups recognize this and facilitate special meetings for women only. These small meetings allow women to share their feelings and concerns in a non-threatening, intimate manner. In September, during Prostate Cancer Awareness Week (September 19-25), PCCN will be hosting the 7th Annual National Support Group Conference. The event will be held at the Fairmont Royal York in Toronto. This conference will bring together support group leaders from across the country. During the two and a half days we will celebrate and learn about the achievements of Canadian prostate cancer researchers and participate in workshops designed to strengthen and help grow the groups. As the Prostate Cancer Canada Network grows in size, stature and visibility, the mission of Prostate Cancer Canada will likewise benefit, leading to increased resources for research, awareness, support and advocacy. Dr. Yves Fradet, MD, FRCSC Chair, Scientific Medical Advisory Committee Every day the team at Prostate Cancer Canada demonstrates their enthusiasm for the Network in many ways – from fielding and passing on telephone enquiries from the newly diagnosed, to sharing expertise in areas like marketing, community development and advocacy. The partnership of Prostate Cancer Canada, Prostate Cancer Canada Network and our local support groups is truly making a difference to the lives of Canadian men and their families. Bob Shiell Prostate Cancer Canada Network prostatecancer.ca RESEARCH RESEARCH (continued) Canadian BRCA 1/2 Prostate Cancer Network Pilot Grants Generously supported by CIBC and RSM Richter Thanks to the generosity of our donors and sponsors, PCC embarked on several exciting research initiatives. A few examples of the research funded by PCC are provided below. Every woman is born with the BRCA1 (breast cancer gene 1) and BRCA2 (breast cancer gene 2) genes. When functioning normally, these genes do not pose any risk to a woman’s health. However, some women may be born with or experience mutations of the BRCA genes through their lifetime. Women who have BRCA mutations are at increased risk for developing breast cancer compared with women who do not have these mutations. Early studies have shown that the male relatives of these women have a higher susceptibility to developing prostate cancer—as much as a 22-fold excess risk. It’s also evident that these men will be diagnosed with aggressive forms of the disease younger than the typical prostate cancer patient and have a higher chance of dying from it. 06 Prostate Cancer Canada is bringing together leading Canadian researchers to assess male carriers of BRCA 1/2 , including those who have not been diagnosed with prostate cancer, through analysis of their saliva or blood. The goal will be to offer novel and individualized treatments for BRCA 1/2 - associated aggressive cancers. This five-year project will support genetic screening of hundreds of men through DNA sequencing. It will benefit from the input of experts in the fields of genomic counseling and surgical, radiation and medical oncology. The results will help with the development of new approaches to disease prevention and treatment through early genetic assessment. As there is currently no group of researchers specifically studying this rare group of patients in Canada, Prostate Cancer Canada is proud to lead the charge in this exciting collaborative effort. In 2009, PCC sponsored 17 pilot studies across Canada. One such research project led by principal investigator Rajiv Chopra of Sunnybrook Health Sciences Centre investigated the potential for magnetic resonance elastography (MRE) to help detect prostate cancer. Prostate tumors are often stiffer than the surrounding gland, and MRE may enable doctors to better locate cancer within the prostate. This research team built prototype devices that would allow the use of high resolution MRE in prostates and tested these devices in preliminary experiments. Based on positive results, the researchers are planning initial clinical trials to investigate the role of MRE for prostate cancer detection. In another pilot study, Dr. Rob Bristow and his colleagues at the Princess Margaret Hospital, studied cells and tissues taken from prostate cancer patients to see if there were defects in DNA repair mechanisms that could be damaged by radiotherapy or chemotherapy treatment. DNA in a cell can be damaged by a variety of factors like radiation and UV light. Cells find and fix damage to the DNA in a collection of processes called DNA repair. Recent studies suggest that some prostate cancer patients have defects in the DNA repair processes, leading to an increased risk of developing cancer and perhaps more aggressive forms of the disease. 07 They found that a number of DNA repair pathways were abnormal at the DNA and RNA levels. To confirm their findings from the laboratory, they studied cell lines and actual prostate cancer tissues to see if the same defects exist in prostate cancer patients’ tumors. They found that a number of DNA repair pathways were abnormal at the DNA and RNA levels. Drugs designed to reverse this abnormality were successful in vitro (in tissue culture) which supports a proof of principle that this study could lead to the creation of a new diagnostic test which will help personalize treatments. prostatecancer.ca New guidelines for early detection 2. THE PSA DISCUSSION In an effort to clarify mixed messaging surrounding the early detection of prostate cancer, Prostate Cancer Canada, in association with the Canadian Urologist Association Patient Information Committee, has created a document that outlines the importance of diagnostic tools, when and how they should be used and the general importance of early detection. Like most cancer diagnostic tools, the PSA blood test comes with its pros and cons; however, men deserve the right to make their own informed decisions regarding the state of their health – even if that decision is to forego or delay treatment. Informed decisions are impossible, however, without regular PSA blood tests and digital rectal examinations (DRE) to assess the likelihood of cancer. 1. EARLY DETECTION OF PROSTATE CANCER The PSA blood test is neither a test for prostate cancer nor an indicator of the type of prostate cancer. PSA levels in the blood increase when the size of the prostate or the number of prostate cells increases. Prostate Cancer Canada advises men and their doctors take the time to discuss the merits of prostate specific antigen (PSA) blood testing followed by a digital rectal examination (DRE) for early detection of prostate cancer. We also strongly recommend that men consider the following schedule for prostate cancer monitoring using PSA blood testing: The usefulness of the test has been debated in medical and political circles for some time. Therefore, when deciding whether to take the test, men should consider the pros and cons and take into account age, risk factors and general health. AGE 40: Establish a baseline PSA value. While the threat of prostate cancer is minimal at this age, it also precedes the onset of benign prostatic hyperplasia (BPH), the natural enlargement of the prostate that commonly occurs with age. The onset of BPH often results in rising PSA over time, and can be confused with the onset of prostate cancer. Your doctor can observe whether your PSA levels have risen, and if so, how quickly. 08 Unless your resulting baseline PSA score is of concern to your doctor, the PSA need only be repeated every 5 years until age 50. Men at higher risk of prostate cancer (eg. men whose father and/or brother developed prostate cancer and/or those of African or Caribbean descent) should begin annual PSA and DRE monitoring at age 40. AGE 50: All men should begin annual or semiannual PSA monitoring if they have not yet done so. A minimal increase in PSA levels against your baseline score often (in consultation with your physician) requires no further action until your next annual test. A significant increase should prompt a discussion with your doctor or urologist about follow up PSA blood tests. The PSA blood test not only helps to diagnose prostate cancer, but helps monitor for recurrence of prostate cancer after treatment. It allows a patient and his doctor to monitor if cancer is suspected, if lifestyle changes have had an impact or if cancer has regressed or spread. Combining the results of PSA blood testing with DRE increases both the diagnostic power and the accuracy of these early detection methods. Pros • Research has shown that a rapid rise in PSA levels over months or years is a very strong sign of aggressive prostate cancer. • By the time a man develops advanced prostate cancer, his PSA is almost always very high. • Widespread testing results in early diagnosis – at the stage when the chances of a cure are good, and there are more options for treatment (e.g. surgery, external radiation, brachytherapy). • The test may not be foolproof but it is the best early detection tool we currently have. 09 Cons • Sometimes increased PSA blood levels are present when clinically insignificant prostate cancers exist – tumors that are smaller than 0.5cc in volume. These tumors may never become life threatening. A high PSA level can also signify non-cancerous conditions. Biopsying these men and treating their cancers may in some cases cause more harm than good. • Normal PSA levels are arbitrary. Sometimes PSA levels may be below normal levels even when cancer is present. 3. WHAT DO THE NUMBERS MEAN? The PSA blood test checks the blood for minute quantities of an enzyme called prostate specific antigen or PSA. A higher than normal amount of PSA in the blood is a possible indicator of prostate cancer, although other conditions of the prostate, such as benign prostatic hyperplasia and prostatitis, also elevate PSA levels. Early Detection Guidelines, were approved by the PCC SMAC and the Canadian Urologist Association Patient Information Committee. prostatecancer.ca 3. Here are the general guidelines for PSA values: 4. RELIABILITY OF THE PSA BLOOD TEST PSA level in nanograms per millilitreUsual description for average man 0 to 4 ng/ml 4 to 10 ng/ml 10 to 20 ng/ml Greater than 20 ng/ml Within the normal range Slightly Elevated Moderately elevated Highly elevated Remember, high PSA readings do not mean that you have prostate cancer. Many factors can contribute to an abnormally high level of PSA in the blood, and the general guidelines presented above are usually adjusted for some of these factors. AGE Aging increases the amount of PSA in the blood, so normal PSA levels are adjusted for age. Any PSA level of under 4 nanograms per millilitre (ng/ml) used to be considered insignificant. With more knowledge about the effects of aging on PSA levels, however, doctors would probably consider a reading of above 2.5 significant for a 45-year-old man and call for further testing. The normal range of PSA levels for men in each age group: 10 Age Range in Years 40 to 49 years 50 to 59 years 60 to 69 years 70 to 79 years PSA normal range in nanograms per milliliter (ng/ml) 0 to 2.5 PSA 2.6 to 3.5 PSA 3.6 to 4.5 PSA 4.6 to 6.5 PSA Age-and race-adjusted cut-off values for PSA (nglml) 40-49 50-59 60-69 70-80 2.0 3.0 4.0 5.0 Still, there is considerable controversy over the value of the PSA blood test. Some studies report that no prostate cancer was found in 70 to 80 per cent of the men who had a biopsy because of an elevated PSA level. The medical community calls a higher than normal PSA level with no evidence of prostate cancer a “false positive”. Also, some researchers estimate that 20 per cent of prostate cancers would be missed if doctors relied only on PSA blood test results. In other words, one out of every five men tested would have prostate cancer and a normal PSA level. A PSA level in the normal range with the presence of prostate cancer is called a “false negative”. There is also a misconception that the PSA blood test is not accurate. When the PSA blood test is conducted in accordance with the instructions provided, accurate assay results should be obtained. The PSA value is not diagnostic for prostate cancer. It should be used in conjunction with clinical evaluation, digital rectal examination, and other laboratory tests or imaging techniques. If the PSA value is inconsistent with clinical evidence, additional testing is suggested to confirm the result. Confirmation of prostate cancer can only be determined by prostatic biopsy. 11 5. REFINEMENTS RACE A man’s race affects his risk of developing prostate cancer and the amount of prostate specific antigen that is within the normal range. Today, doctors may consider both a man’s age and his race when determining whether his PSA blood test result is unusual. The following table shows age-and race-adjusted cut-off values for PSA – or in other words, the PSA levels at the top end of the normal range for men of particular ages and races. AgeAsian men So many factors can affect the level of prostate-specific antigen in the blood that one might ask whether the PSA blood test is useful in the diagnosis of prostate cancer. The answer is a resounding yes. The PSA blood test, especially when combined with a digital rectal examination (DRE), is a good indicator of the possibility of prostate cancer. The PSA blood test does not predict either the presence or absence of prostate cancer, but it does alert men and their physicians to the possibility of the presence of an early-stage cancer in the prostate. Caucasian men Men of African descent 2.5 3.5 4.5 6.5 2.0 4.0 4.5 5.5 Physicians have made refinements to the PSA blood test and to the analysis of PSA blood test results to improve its reliability as an indicator of prostate cancer. Doctors now consider the speed at which PSA levels rise, how quickly PSA levels double in amount (PSA doubling time), the sort of prostate-specific antigen in the blood (free versus total PSA), and the amount of PSA in relation to the size of a man’s prostate (PSA density). PSA doubling time: PSA doubling time relates PSA levels to time. It measures the time it takes for your PSA value to double. Sometimes, PSA doubling time is helpful in pre-biopsy guesses about whether a man has cancer and whether this cancer is likely to be aggressive or to have spread. Percentage of Free to Total PSA (%fPSA): This measurement is a ratio comparing the amount of free PSA to the total amount of PSA in the blood. Free PSA travels alone in the blood; it is not bound to any other blood proteins. This unbound or free PSA comes from BPH, not prostate cancer. So the higher a man’s percentage of free PSA, the less likely it is that prostate cancer is to blame. Testing for free PSA (called %fPSA in some medical reports) is useful for men whose PSA level falls between 4 and 10, the grey area in which BPH could be the culprit. Readings of prostatecancer.ca greater than 25 per cent free PSA (25 %fPSA) indicate that much of the elevated PSA is caused by BPH. A reading of under 10% suggests that prostate cancer is causing this elevation and, furthermore, that this cancer is probably large and in need of immediate treatment. PSA density (PSAD): This measurement compares the size of a man’s prostate, which is determined by a transrectal ultrasound (TRUS), with his PSA level. In simple terms, the doctor divides the PSA value by the size (or mass) of the prostate. If, for example, your PSA level is 4 and the size of your prostate in grams is 32, you would divide 4 by 32 to get a PSA density of 0.125. Usually, a PSA density under 0.07 is considered fairly safe, one between 0.07 and 0.15 could be attributable to either BPH or prostate cancer, and one above 0.15 indicates an increased likelihood that cancer is present. Prostate volume measurements, and thus PSA densities, are subject to TRUS operator/interpreter variability. 6. OTHER CONDITIONS OF THE PROSTATE 12 Benign prostatic hyperplasia (BPH) and prostatitis can also increase the amount of PSA found in a man’s blood. BPH, a non-cancerous enlargement of the prostate, can elevate PSA levels because a larger prostate manufactures more prostate-specific antigen. Also, any prostate condition can weaken the tissues in the prostate gland, allowing more PSA to leak into the blood. Usually, PSA levels caused by BPH do not go as high as those caused by prostate cancer, nor do the levels tend to rise as quickly. However, most likely, if you have a higher than normal PSA level or one that is steadily rising, your doctor will discuss the value of having a prostate biopsy to determine whether cancer or some other condition is to blame. The nomograms behind the 12 PCATs have an average accuracy rate of 80 per cent, and are of significant benefit to patients in that they eliminate bias and subjectivity that is inherent in the perspective of individual clinicians and caregivers. To create this program for Canadian men, Prostate Cancer Canada partnered with a team of highly recognized researchers led by Dr. Pierre Karakiewicz, MD, urologist and director of the Cancer Prognostics and Health Outcomes Unit at the University of Montreal Health Centre. Information published on the Prostate Cancer Canada website is provided for informational and educational purposes only. Information provided on this website, including information derived from the Prostate Cancer Assessment Tools (PCATs) and the prostate cancer nomograms, is not designed or intended to constitute medical advice or to be used for diagnosis. The PCATs are intended to provide information on your condition and to help inform your consultations with medical professionals. The information obtained from this website should not be a substitute for medical advice from a qualified medical professional. Prostate Cancer Canada and the Centre Hospitalier de l’Université de Montréal assume no responsibility or liability for any consequence resulting directly or indirectly for any action or inaction you take based on or made in reliance on the information, services, or material on or linked to this site. 13 Prostatitis, an inflammation of the prostate, can also affect PSA levels. Because this inflammation can break down tissues in the prostate gland, it can enable quite a bit of prostate-specific antigen to escape fairly quickly into the blood. An acutely inflamed or infected prostate can increase a man’s PSA level to 100 nanograms per millilitre (ng/ml) or higher. After treatment for prostatitis, it can take up to six months for PSA levels to return to normal. 7. ASSESSING PROSTATE CANCER RISK Prostate Cancer Assessment Tools (PCATs) are based on nomograms published in the Journal of Urology to ensure highly accurate assessments. Nomograms are paper-based decision-making statistical tools that are comprised of information from thousands of real-life observations from documented prostate cancer cases. The tools assist patients and physicians in decision-making by providing calculated predictions of the outcomes of various stages of prostate cancer. prostatecancer.ca Thank you to our Donors Donors (continued) Prostate Cancer Canada would like to recognize all donors whose generosity helps support our cause. Through research, public education, support and awareness, you are helping us become a global leader in the fight against prostate cancer. Due to space limitations we do not have the opportunity to recognize all those who make our work possible. As a result, this list includes donors who have made a financial contribution of $1,000 or more from April 1, 2009 to March 31, 2010. Should you note any errors or omissions, please accept our most sincere apologies and contact us at 1-888-255-0333 ext 242. Thank you. $100,000 + Canada Safeway Ltd. Canadian Prostate Cancer Network Randy Remington Prostate Fund $25,000 - $99,999 14 Bayer Inc. CIBC Estate of Austin Conway Masonic Foundation of Ontario Mr. Lube Foundation RBC Foundation Sanofi-Aventis Canada Inc. Shorcan The GlaxosmithKline Foundation The KPMG Foundation The Richter Charitable Foundation $10,000 - $24,999 ACI Brands Inc. Amgen Canada Inc. Robert K. Barrett British Columbia Foundation for Prostate Disease Cedarhurst Golf Club Inc. Estate of Douglas Robert Wallis Evald Torokvei Foundation Fairmont Hotels & Resorts Jack. J. Holtzman Ontario Masons - Toronto Humber Valley District Penn West Energy B. Myron Rusk SCA North America/ Canada Inc Schwartz & Co. Ltd. Sportsgrants Inc. The D. H. Gordon Foundation The HYDRECS Fund The Survivors Prostate Cancer Golf Tournament Whitlock Motorsports $5,000 - $9,999 Abbott Laboratories Canada Ltd. Avison Young Commercial Real Estate (Ontario) Inc. Barrick Heart of Gold Fund Lynn Bevan BMO Capital Markets BMO Employee Charitable Foundation Brookfield Partners Foundation Canadian Western Bank Daytona Capital Corp. Deloitte & Touche LLP Enbridge Gas Distribution Inc. Endla & John Gilmour Foundation Rochelle Feldberg Jeffrey Feldberg First National Financial LP Grafton-Fraser Inc. John R. Ing ING Real Estate Canada LP Leon’s Furniture Limited Michael Lewicki Gary MacDonald Mercedes-Benz Canada Inc. Philip P. Mostowich Oakah and Dorothy Jones Foundation Ontario Masons - York District Osler, Hoskin & Harcourt LLP Neil Parkinson Prostate Cancer Foundation BC GeorgeRatner Rio Can Real Estate Investment Trust RSM RUV Management Zachary Samuels Stikeman Elliot LLP T. A. Tait TD Bank Financial Group The Bolt Supply House Ltd. The Charles Norcliffe and Thelma Scott Baker Foundation TSX Group $2,500 - $4,999 ARC Energy Trust Jim Armstrong Avalon Prostate Cancer Support Group BalancePlus Sliders Inc. C.H.A.T. Student Council Audrey Cameron Gregory Collings Paul Collings Kevin Dancy Eclipse Medical Inc. Encore Wire Corporation Estate of Christopher E. J. Humphreys Yves Fradet Nedo A. Gizzi Godfrey Family Foundation Goldcorp Inc. Golf Town Ruben Goulart Stephen Graham Deborah Harper Haywood Securities Inc. Eleanor Holt Intuit Canada Limited Donation Matching Program Tom Kierans Randy Magnussen F. R. Matthews Peter Myers Ontario Masons - St. Thomas District Murray Pask Patrick and Barbara Keenan Foundation Donald B. Peart Henry Piworowicz Prime Projects Ltd. Curtis Prosko Richard Rooney Shipp Corporation Ltd. George Smith Robert Sutherland The J.E. Panneton Family Foundation Tom’s Place VS LLP Daniel Walshe Thomas C. Wright $1,000 - $2,499 2102583 Ontario A Night To End Prostate Cancer A & A King Family Foundation Bill Acton AGF Management Limited Allan Berj And Mombee American Medical Systems Canada Inc. J. C. Anderson Gord Angevine AON Reed Stenhouse Inc. Armco Capital James Ayearst Ted Bailey Arthur & Elle Bargen Marina Barnstijn David Beamish Paul Beeston Norman B Bell Douglas Bennett Ben’s Pharmacy Roland Bertin John Bigham BMO Bank of Montreal Boston Pizza Bowne of Canada Ltd. George Brazier Arvey Brenner Wesley P. Brown Sandee Butterley Lowrey A. Cain Robert Cain John A Campbell Canadian Cancer Society Capital Packers Inc. Brian Carr Leslie Carter Michael F Casey Tim W Casgrain Yves Chabot Jack Chisvin Church of Our Saviour The Redeemer Andrew D. Clarke Richard Clarke Edward G Cleather J.B. Colburn Allan Collings William A Corbett E H Crawford Credit Union Atlantic Crestview Chrysler Dodge Jeep John & Mary Crocker Bob Cronin Warren Crosbie Rob Daniel Gord Davis Dell Direct Giving Program Stan Doel John Dove Dover Flour Lorne Dubros Brian Dunn Eddie’s Men’s Wear Ltd. Edmonton Exchanger & Manufacturing Ltd. EnCana Cares Foundation Engineering Student Society “A” Eric Van Viegen Deborah Evans Howard Evans Eyelogic Systems Inc. Ron Fath Saul Feldberg Bernie Ferbey Mario Ferrara George Fink Michael Fiorino Shawn Fitzpatrick Fleming Foundation Henry Fong Franklin Templeton Investments Front Street Capital 2004 George Gagnon Duane Gee GM Verge Investments Goodmans LLP George Gosbee Michael J. Gough Theresa Gouthro Green Hunt Wedlake Inc. Randy Gregory Brenda Groves Barry J Gunn Norman R Hain Harley Hotchkiss Robert C. Howard I.M.P. Group Ltd. IBM Canada Ltd. Catherine Inglis Iona Resources Holdings Inc. Kevin Irons Kristian Isberg Bengt Jansson Jardine Lloyd Thompson Canada Inc. Bruce Jenkins Jonel jim Construction Wendy Jones Michael Kearns Hubert Keenleyside Jim & RonaKehoe Kevin Kimsa Kiwanis Club of Calgary Chinook Kevin Knight Tom Knowlton Saul Korman Korry’s Clothiers to Gentlemen KPMG T. H. Laidlaw Leddy Exploration Limited Leipert Financial Group David H Lewis Londonderry Chrysler James A Lore Nancy Love Allan Lundell Manfred Lupke Dan J MacDonald Mackie Research Capital Corporation Andrew Maitland John Mandrusiak Paul Marchildon Marco Maritimes Ltd. Lori Martai Fasken Martineau Ronald & Marlene Masleck Mastermind Toys Gordon Mauchel McCarthy Tetrault LLP John & Deni McCrae 15 prostatecancer.ca board of directors / senior management Donors (continued) 16 Isabell McDorman Donald McGregor Hugh McLean Gary M & Beverley McLeod Peter And Fern Mcmahon/ Holland Douglas J Mervyn Mark Mettrick Thomas Miller Morneau Sobeco Scott Morrison Nelson Lumber Darrell Newton Nexans Canada Inc. NLS Welding and Contracting Inc. Northern Cables Inc. Sean Nother Nova Scotia Power Taryn O’Brien Ontario Masons - Grey District Ontario Power Generation Inc. Order of the Eastern Star, Tweed Chapter #148 Neil Parkinson David Pauli Malcolm Peake Ed Pearce Ian Pearce Terry S. Peters Jon Picken Provincial Industrial Roofing ProWerx Disposal Ltd. Geroge Przybylowski R. Magnussen Consulting Ltd. RBC Dominion Securities Inc. Rio Tinto Alcan Inc. C E Ritchie Rob Ritchie Rogers Group of Companies William Ross Ryan ULC Mark Sack James S. Saloman SAS Saskatchewan Gaming Corporation SaskTel Sayal Charitable Foundation Shadowcorp Investments Limited Ken Shannon Shawflex Sherebrooke Investments Limited Robert Shiell Signature Capital James Sinneave Rick Kenneth Skauge Craig Kenneth Skauge Tom A Skinner Sleepy Hollow Country Club Ltd. Howard Sokolowski St. Andrew’s East Golf and Country Club A. Steele Hellyer’s Food Market Steve & Kathy Hellyer Stikeman Elliott - Calgary Stone & Co. Ltd. Summit Vale and Controls Inc. Super Cue Billiards & Golf Judy Sutherland Joey Tanenbaum Stephan Tapp TELUS The Barnes Family Charitable Foundation The Charitable Gift Funds Canada Foundation The Data Group of Companies The Duguid Family Fund The Jewish Foundation of Manitoba The Leonard Albert Family Foundation The McGraw Hill Companies Thomas, Large & Singer Inc Tickets-Beer For a Cure Toronto Hydro Corporation Toronto Police Amateur Athletic Association Ken Travis Edward D Trewin Truwan Management Limited Ultimate Fitness Inc. Theo Van der Kwast Veroli Cultural Society Melvin Vogel Rod P. Wacowich Lee And Nancy Watchorn James W. Watt Wellington West Capital Markets Michael Williams Alfred Wirth James Wolfe World Trade Centre Timothy A. Wright April 1, 2009 - March 31, 2010 Lee Watchorn, Chair Jack Brill Andrew D. Clarke, Vice Chair Dr. Robert Bristow, Chair Mark Dailey, Director Dr. Yves Fradet, Chair Tom Godber, Director Michael J.Gough, Director Stephen Graham, Vice Chair Eileen Greene Gordon I. Kirke, Director Dr. Laurence Klotz, Chair Senior Management Steve Jones President & CEO Prostate Cancer Canada Rebecca von Goetz Vice President, Marketing & Communications Prostate Cancer Canada Rocco Fazzolari Vice President, Finance & Administration Prostate Cancer Canada Donald McInnes Ian MacVicar, Treasurer & Secretary Patrick Meneley, Chair Peter Myers Ted Nash Neil Parkinson George Przybylowski, Chair Pradeep Sood, Director Robert Watson Robert Zed, Director Steve Jones, President & CEO Scientific & medical advisory committee Dr. Yves Fradet Chair, Uro-oncologist Dr. Colleen C. Nelson Vice Chair, Basic Scientist Dr. Robert Bristow Radiation Oncologist Dr. Kim N Chi Medical Oncologist Dr. Joseph Chin Uro-oncologist Dr. Laurence Klotz Uro-oncologist Clinician Scientist Award Panel Dr. Laurence Klotz, Chair Dr. Armen G. Aprikian Dr. Robert Bristow Dr. Scott North Dr. Tom Pickles Dr. Jeremy Squire Dr. Danny Vesprini Science Officer Dr. Eric Winquist Networks & Partnerships Committee Pilot Grant Panel Dr. Yves Fradet, Chair Dr. Kim Chi Vice Chair, Clinical Dr. Colleen Nelson Vice Chair, Basic Dr. Tarek Bismar John Blanchard Dr. Mario Chevrette Dr. James R. Davie Dr. Gerardo Ferbeyre Dr. Michael Fraser Science Officer Dr. Masoom A Haider Dr. Jeffrey Medin Dr. Matthew Bruce Parliament Dr. Tom Pickles Dr. Michael Pollak Dr. Alan So Dr. Emma Thomlinson Guns Dr. Theodorus H. Van Der Kwast Dr. Vasundara Dr. Venkateswaran Dr. Robert Bristow, Chair Dr. Armen Aprikian Dr. Mario Chevrette Dr. Stuart Edmonds Dr. Larry Goldenberg Emma Halls Professor John Mills Dr. Colleen Nelson Dr. Fred Saad Dr. Howard Soule Dr. Christine Williams 17 Patient & Public Education Committee Dr. Joseph Chin, Chair Dr. David G. Bell Dr. Bryan Donnelly Dr. Pierre Karakiewicz Dr. Andrew Loblaw Dr. Robert Siemens Dr. Peter Venner Peter Pommerville Bob Shiell Dr. Peter Venner Rebecca von Goetz For biographies of committee members, please visit prostatecancer.ca prostatecancer.ca PROSTATE CANCER CANADA CONDENSED FINANCIAL STATEMENTS CONDENSED BALANCE SHEET For 12 months ending March 31, 2010 Current Assets Capital Assets 2009/10 $’000s 2008/09 $’000s 11,708 127 6,073 173 Total Assets 11,835 6,246 Liabilities (note 2) 5,937 3,777 Net Assets (note 3) 5,898 2,469 18 Total Liabilities and Assets 11,835 6,246 CONDENSED STATEMENT OF OPERATIONS AND CHANGES TO NET ASSETS For 12 months ending March 31, 2010 2009/10 2008/09 Gross Revenue Charitable Programs (note 4) 14,768 6,884 8,389 3,077 Net Revenue Before Expenses 7,884 5,312 Expenses (Fundraising, management and general administration) 4,455 3,341 Net Surplus After Expenses 3,429 1,971 Net Assets Start of Year 2,469 498 Net Assets End of Year 5,898 2,469 NOTES TO CONDENSED FINANCIAL STATEMENTS 1. The condensed financial statements are derived from the financial statements audited by Deloitte & Touche. Copies of the audited statements are available on request. Certain prior year’s figures have been reclassified to conform with current year’s presentation. 2. The Foundation funds research grants and projects. Current liabilities include a provisional amount of $5,106,012 for research. 3. Net Assets include a Research Reserve Fund of $4,680,000, established to fund new prostate cancer related projects. 4. Charitable Programs include mission investments in research, support groups and public education.