GENERALIZED ANXIETY DISORDER IN CHILDREN AND ADOLSCENTS: IMPLICATIONS FOR RESEARCH AND PRACTICE
Transcription
GENERALIZED ANXIETY DISORDER IN CHILDREN AND ADOLSCENTS: IMPLICATIONS FOR RESEARCH AND PRACTICE
GENERALIZED ANXIETY DISORDER IN CHILDREN AND ADOLSCENTS: IMPLICATIONS FOR RESEARCH AND PRACTICE Leah M. Reuschel 42 pages April 2011 This review summarizes the existing literature related to foundations of behavior, assessment and measurement, applications to therapy, cultural considerations, ethical and professional issues, and research needs regarding the provision of mental health treatment for generalized anxiety disorder in children and adolescents. CLINICAL COMPETENCY PROJECT APPROVED: Date Alvin E. House, Chair Date Margaret M. Nauta, Member GENERALIZED ANXIETY DISORDER IN CHILDREN AND ADOLSCENTS: IMPLICATIONS FOR RESEARCH AND PRACTICE LEAH M. REUSCHEL A Clinical Competency Project Submitted in Partial Fulfillment of the Requirements for the Degree of MASTER OF SCIENCE Department of Psychology ILLINOIS STATE UNIVERSITY 2011 GENERALIZED ANXIETY DISORDER IN CHILDREN AND ADOLSCENTS: IMPLICATIONS FOR RESEARCH AND PRACTICE Leah M. Reuschel 42 pages May 2011 Generalized anxiety disorder (GAD) is a widespread, debilitating disorder in children and adolescents. Excessive anxiety in childhood causes great individual distress and functional impairment (Albano et al., 2003) and is a major risk factor for mental health disorders later in life. These facts call attention to the importance of early intervention and a greater understanding of GAD in children and adolescents. This review discusses foundations of behavior, methods of assessment and measurement, applications to therapy and therapeutic considerations, cultural considerations and relevance to special populations, relevant ethical and professional issues, and research challenges and needs regarding childhood GAD. CLINICAL COMPETENCY PROJECT APPROVED: Date Alvin E. House, Chair Date Margaret M. Nauta, Member CONTENTS Page CHAPTER I. INTRODUCTION Diagnosis Previous diagnosis: OAD Rape Culture and Rape Myths II. FOUNDATIONS OF BEHAVIOR Symptoms of GAD Cognitive Symptoms. Physiological Symptoms. Behavioral Symptoms. Phenomenological Symptoms. Etiology Epidemiology Development/Age of Onset Comorbidity III. ASSESSMENT AND MEASUREMENT Multifaceted Assessment Methods of Assessment Clinical Interview Checklist Measures Behavioral observation IV. APPLICATIONS TO THERAPY Cognitive Behavior Therapy CBT Interventions. Relaxation Training Exposure Treatment Systematic desensitization Flooding exposure Cognitive Restructuring Acceptance-Based Behavior Therapy Review of CBT Treatment Outcome Literature Individual CBT Group CBT Technology Applications in CBT Family and Parent-based Treatment Communications Family Therapy 1 1 1 1 2 4 4 6 7 8 8 10 10 11 12 12 13 13 14 17 17 17 18 18 20 21 22 22 23 23 24 25 27 28 29 Contingency Management/Parent Training Play Therapy Pharmacological Treatment V. VI. CULTURAL CONSIDERATIONS AND RELEVANCE TO SPECIAL POPULATIONS 33 RELEVANT ETHICAL AND PROFESSIONAL ISSUES 36 Confidentiality The Need for Knowledge Versus Protection of Child Participants The Stigma Created by Labeling Youth with Mental Health Disorders Exposure VII. RESEARCH CHALLENGES AND NEEDS Methodological Issues VIII. 29 30 32 CONCLUSION 36 37 38 39 39 41 42 1 Generalized Anxiety Disorder in Children and Adolescents: Implications for Research and Practice Generalized anxiety disorder (GAD) is a prevalent, debilitating disorder in children and adolescents. Excessive anxiety is the most common mental health problem experienced in youth (Albano, Chorpita, & Barlow, 2003) and causes individual distress and functional impairment throughout children’s lives (Albano et al., 2003). Furthermore, excessive childhood anxiety is a major risk factor for mental health disorders later in life. These facts call attention to the importance of early intervention and a greater understanding of GAD in children and adolescents. Diagnosis Generalized anxiety disorder is an anxiety disorder distinguished by excessive worry about several areas of one’s life. GAD is defined in the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR; American Psychiatric Association, 2000) by excessive, difficult-to-control anxiety and worry about a number of events and activities that is accompanied by various physiological symptoms, i.e., muscle tension, restlessness/feeling keyed up or on edge, difficulty concentrating/mind going blank, being easily fatigued, irritability, and sleep disturbance. In children, the diagnosis only requires at least one physiological complaint to be present as opposed to at least three symptoms in adults (4th ed., text rev.; DSM–IV–TR; American Psychiatric Association, 2000). Previous diagnosis: Overanxious Disorder In previous editions of the DSM (American Psychiatric Association, 1994), excessive worry and anxiety in children was labeled Overanxious Disorder (OAD), a diagnosis present in the “Disorders of Childhood” section of the DSM-III (American Psychiatric Association, 1980), and DMS-III-R (American Psychiatric Association, 1987). The diagnostic category of OAD, 2 however, had several problems including limited reliability, lack of external validity, overdiagnosis, inappropriateness of the criteria, lack of distinctiveness from other disorders of childhood, and uncertain relationship to adult disorders (Werry, 1991). Now it is recognized that child, adolescent, and adult manifestations of excessive worry and anxiety symptoms are fundamentally equal (House, 2002a). Thus, due to the lack of distinctiveness between youth and adults symptoms, the former diagnosis of OAD was subsumed under the revised diagnosis of GAD in the DSM-IV (American Psychiatric Association, 1994). This revision, however, does not generally reflect a developmental perspective, thus clinicians have to translate the diagnostic criteria into conditions that appropriate for a child’s age, development, gender, and culture (Moore, March, Albano, & Thienemann, 2010). Foundations of Behavior Children and adolescents of both genders commonly experience anxiety symptoms (Bernstein & Borchardt, 1991). Although anxiety, at certain levels, serves adaptive functions, intense anxiety and worry can be quite debilitating. Anxiety disorders are the most frequent mental health problems that afflict children and adolescents (Albano, Chorpita, & Barlow, 2003). Childhood anxiety disorders cause individual distress as well as a broad range of functional impairment throughout a child’s life (Albano et al., 2003). Furthermore, excessive childhood anxiety is a major risk factor for adult mental health disorders. Childhood anxiety disorders are often followed by adult anxiety disorders (Kim-Cohen et al., 2003), depression (Kovacs, Gatsonis, Paulauskas, & Richards, 1989), and substance abuse (Kushner, Sher, & Beitman, 1990), calling attention to the importance of early intervention. The onset of GAD may be gradual or sudden and, unsurprisingly, symptoms are often exacerbated by stress (Rapoport & Ismond, 1996). 3 Because anxiety disorders are prevalent in and distressing to children and adolescents, a vast comprehension of anxiety in this population is needed. However, our understanding of anxiety in youth continues to be limited. Because youths’ mental capacities and emotions are constantly developing and shifting, it can be difficult to distinguish between fears and worries that are normal for a child’s developmental stage and those that may be of concern and necessitate special attention. “Children’s Fears and Anxieties” (2004) outlines some typical fears and worries of youth at certain developmental levels. Newborns normally fear loud noises and falling, while a fear of strangers usually begins around 6 months and continues through the age of 2 years. It is typical for pre-school age children to be afraid of separation from their parents, darkness, paranormal creatures (e.g., ghosts and monsters), big animals, and masks. Normal worries in children who are older include unsuccessful results in school, family deaths, and tragic occurrences in the news such as terrorist attacks, war, kidnappings, and natural disasters. Adolescents commonly have anxieties about their personal future and future of the world, as well as social and sexual events and performances. According to trait models of personality such as the Five-Factor Model (e.g., McCrae & John, 1992), Neuroticism, or the tendency to experience negative emotions such as anxiety, is a basic personality dimension. Anxiety is a fundamental emotion that at certain levels serves adaptive functions such as motivation, protection, and survival (Moore et al., 2010). Childhood fears, worries, and anxieties must be considered in their developmental context and only become a problem if they persevere and cause serious personal distress, hinder development or education, or greatly interfere in familial or social relationships (“Children’s Fears and Anxieties”, 2004). Nevertheless, even subthreshold levels of anxiety in children can result in considerable impairment and may necessitate attention and treatment (Moore et al., 2010). 4 Some researchers argue that because anxiety and depression are similar in several aspects they should be combined into a single construct termed Negative Affectivity. Negative Affect can be described as a general feature of subjective distress and includes a wide range of negative mood states, including anxiety, depression, disgust, and hostility (Watson, Clark, & Carey, 1988). In terms of empirical and conceptual overlap, anxiety is closely related to depression. Several studies have shown strong correlations in several measurements of anxiety and depression in diverse samples, including children (Blumberg & Izard, 1986; Wolfe et al., 1987). However, a major difference between anxiety and depression is the feature of anhedonia, which is present in depression and absent from anxiety (Watson et al., 1988). While the strong connection leads some researchers to propose that anxiety and depression are variations of a single disorder, most personnel in the field continue to consider that the basic distinction is appropriate and valid (Watson et al., 1988). Symptoms of GAD Anxiety itself can be seen as a multifaceted construct that can be studied from four different approaches—cognitive, physiological, behavioral, and phenomenological. These aspects of anxiety are discrete categories; rather they overlap and interconnect. Cognitive Symptoms. Worry and the disturbance of mental processes (e.g., thinking, planning, abstract reasoning, problem solving, and recall) encompass the cognitive features of anxiety (Kendal et al., 2004). With GAD, there is an overall attitude of apprehension. Children and adolescents with GAD are often described as self-conscious, perfectionistic “worriers” (Beidel & Turner, 2005; Eisen & Kearney, 1995). The uncontrollable worry element of GAD may focus on several 5 general life themes such as the future, past events, and competence in areas including school, sports, and peer relationships (Albano et al., 2003). Children with GAD are often perceived as “little adults” because in addition to the typical worries of youth, many of their worries often revolve around “adult” themes such as family finances, health and safety of loved ones, relationships, schedules, punctuality, and tragic events,—topics that normally only concern an older population (Kendall, Pimentel, Rynn, Angelosante, & Webb, 2004). In addition, these children often display perfectionistic tendencies, such as scrupulously completing or repeatedly redoing small tasks (e.g., simple homework assignments) until they feel these tasks are completed perfectly. Often, adults will perceive these perfectionistic behaviors as evidence of a child’s maturity and thoroughness and will inadvertently reinforce the child for these behaviors. While the worries and perfectionistic tendencies may be adaptive for some children, these behaviors become a clinical concern when they interfere with other aspects of development and adjustment (Kendall, et al., 2004). Cognitive distortions, most often “what if…” statements about wide-ranging stimuli, infuse these children’s thought processes on a fairly continuous basis. Additionally, these children overestimate the possibility of harmful outcomes, exaggerate anticipated consequences to a disastrous degree, and undervalue their own capacity to cope in adverse situations (Albano, et al., 2003). Silverman, La Greca, and Wasserstein (1995) demonstrated that non-clinical children worry about low occurrence events as well, but children with GAD may not be able distinguish that such events have a low likelihood of actually happening. It appears that it is not the content or number of worries, but rather the frequency, intensity, and functional impairment of worry that distinguishes between high levels and low levels of anxiety in children and adolescents (Beidel & Turner, 2005). In fact, a study performed 6 by Weems, Silverman, and La Greca (2000) demonstrated that non-clinical children reported just as many worries as the clinical samples, signifying that intense worry may lead to a reaction of uncontrollability over the worry process. The same study cited that children with GAD reported an average of 5.74 worries, spanning an average of 4.82 areas. The most common themes of worry in youth with GAD included school, health, disasters, personal harm, and the future. The children’s most frequent worries were in the realms of friends, peers, school, health, and performance, while their most intense worries were in the areas of war, personal safety, tragedies, school, and family (which are comparable to the list of typical developmental fears presented earlier). Consistently, Muris et al. (2002) described that the worries most often reported by children are not the same worries they experience as most intense. There are developmental differences in regard to youth worry. Younger children (aged 68 years) reported fewer worries about appearance, performance, and minor issues as compared to an older group (aged 12-16 years). Moreover, gender differences are also present in the frequency of worry. Girls generally score higher than boys on measures of anxiety and specific measures of worry frequency (Vasey & Daleiden, 1994). When the cognitive symptoms of GAD and specific phobias were compared, children with GAD were found to score significantly higher in both the intensity and the total number of worries present (Muris et al., 2002). However, few group differences in the frequency and content of worry were discovered; although notably, children with specific phobias reported more worries about family and the health of others, while those with GAD worried more about scapegoating and the future. Physiological Symptoms. 7 The physiological element of anxiety revolves around the biological effects anxiety has on the body. Physical symptoms generally reflect elevated sympathetic autonomic nervous system activity and include increased heart rate and blood pressure, increased muscle tension, muscle tremor, alterations in salivation and perspiration, bodily temperature changes, and modifications of stomach gastric and acidic actions (Beidel & Turner, 2005). These symptoms are caused by the release of cortisol and epinephrine in the brain when a threat is detected (Wood & McLeod, 2008). These physiological changes are thought to serve an adaptive function by enhancing motor performance for fight or flight behaviors. In one sample, Tracey, Chorpita, Douban, and Barlow (1997) found that youth with GAD endorsed experiencing several physical symptoms, including restlessness (74% of the sample), irritability (68%), difficulties concentrating (61%), sleep disturbance (58%) headaches (36%), muscle tension (29%), and stomachaches (29%). Behavioral Symptoms. The behavioral part of anxiety involves avoidance or escape behaviors that are activated when an individual is confronted with fear-inducing cues. The avoidant behavior is then negatively reinforced with a reduction of fear and decline of arousal. Excessive anxiety is commonly conceptualized as being an exaggerated, distressful, non-functional arousal response that expanded from what was once an adaptive escape reaction from danger (Borkovec, Alcaine, & Behar, 2004). In GAD, the anxiety and avoidance behavior generalizes to non-threatening cues; as a result, numerous objects and events that were previously harmless become cues that evoke anxiety. In essence, individuals with GAD are in a constant state of vigilance (Rapoport & Ismond, 1996). 8 Due to the self-conscious, perfectionistic nature of youth with GAD, they ask for and require repeated reassurance from others (Beidel & Turner, 2005; Eisen & Kearney, 1995). Children and adolescents with GAD usually demonstrate a rather debilitating restriction of ageappropriate social functioning and activities (Eisen & Kearney, 1995). Phenomenological Symptoms. Lastly, the phenomenological aspect of anxiety involves one’s subjective experiences and feelings of anxiety. Anxiety is a natural human emotion with which everyone is familiar. The feelings include an uncontrollable sense of urgency, impending doom, nervousness and apprehension. This anticipatory anxiety is usually present in these children, especially in situations in which their performance may be evaluated (Rapoport & Ismond, 1996). House (2002b) noted that children suffering from GAD often manifest with a great amount of personal distress and appear miserable. Etiology There is relatively little known about the etiology of GAD in children because research on this topic has been fairly sparse (Kendall, Pimentel, Rynn, Angelosante, Webb, 2004). However, Albano et al. (2003) suggested that anxiety is a function of several features, including genetics, temperament, psychosocial factors, and parenting/family interactions (Barlow, 2002). Although research with adults has suggested a potential genetic contribution to GAD (Brown, 1999), no studies of this kind have been conducted in children. However, the overall findings indicate that genes significantly contribute to a general vulnerability for anxiety (Barlow, 2002). Recent research indicates that in children this general vulnerability for GAD may also be related to depression, i.e., a shared genetic risk factor (Albano et al., 2003). 9 Additionally, other research suggests that the general vulnerability of anxiety may be related to the temperament of a child (Kagan, 1997). This research is consistent with trait view, which considers clinical anxiety to be extreme versions of personality characteristics distributed in the general population. Research in this area has focused upon the relation between anxiety and broader personality variables, such as the “Big Five” personality traits. Clark and Watson (1991) studied childhood anxiety in relation to the tripartite model of emotion and found that the personality factors of Negative Affect and Physiological Hyperarousal were positively related to anxiety in children. Researchers have also paid some attention to the role of cognitive patterns in the causation of anxiety disorders in children. In both adults and children, combinations of cognitive factors such as negative self-talk, anticipation of threat, and self-questioning may add to the development of detrimental anxiety symptoms and disorders such as GAD (Kendall, 1991). However, further research is required to better understand the function of negative cognitive factors in childhood anxiety. Furthermore, parenting behaviors and parent-child attachment styles can contribute to the development and maintenance of anxiety in children (Maid et al., 2008). Two of these specific parenting characteristics that impact childhood anxiety are acceptance and modeling of anxious behaviors. Low warmth and little parental acceptance can cause children to be more prone to experience anxiety (Wood, McLeod, Sigman, Hwang, & Chu, 2003). Parents who experience anxiety and lack effective coping strategies transmit similar behaviors to children through modeling, also causing childhood anxiety (Maid et al., 2008). Some data suggest a possibility of significant differences between child- and adult-onset GAD (Hoehn-Saric, Hazlett, & McLeod, 1993), which raises several questions regarding the etiology of the disorder. Although results are mixed (Brown, 1999), some researchers suggested 10 that the etiology of GAD may differ depending on the age of onset (Kendall et al., 2004). Brown (1999) wondered if, perhaps, childhood-onset GAD is more genetic-based while adult-onset is more related to environmental effects. However, further research regarding the etiology and course of GAD is needed to further explore this hypothesis. Similarly, as Kendall et al. (2004) suggested, further exploration and research of biological factors, cognitive patterns, parenting styles, early stressors, and temperament is warranted regarding the etiology of childhood GAD. Epidemiology As stated previously, anxiety disorders are the most common mental health disturbances in youth (Albano, Chorpita, & Barlow, 2003). In their literature review of the epidemiology of anxiety disorders in children and adolescents, Costello, Egger, and Angold (2004) concluded that at current or three month prevalence estimates, anxiety disorders in youth range from 2-4 percent. At six month to 12 month estimates, the rates escalate to 10-20 percent, while the lifetime estimates are only slightly higher. Moreover, GAD was found to be the most common of the anxiety disorders to affect children and adolescents. It appears that the prevalence of GAD may be higher in environments that exceedingly prize and value success and achievement (Rapoport & Ismond, 1996). Rapoport and Ismond (1996) acknowledged that in upper socioeconomic levels where performance expectations are high, the existence of GAD is common. Development/Age of Onset Costello, Egger, and Angold (2004) reported that in a sample of youth who developed an anxiety disorder before the age of 16, the total mean age of onset for GAD was 5.8 years old (standard deviation = 5.7 years), which was the youngest for all anxiety disorders and unipoloar depressive disorder. Broken down by gender, males showed a younger average onset age of 11 GAD by over 2 years; the average age of onset in males was 4.6 years and in females was 6.8 years. Also of note, compared to all other anxiety disorders and unipolar depressive disorder, GAD had the largest interquartile range around the mean ages of onset at 12 years. This suggests that, unlike childhood Panic Disorder and Separation Anxiety Disorder that have relatively short windows for onset with quite small interquartile ranges at 3 years and 4 years respectively, GAD has a relatively long window for possible onset in childhood. The course of generalized anxiety disorder tends to be chronic, and research shows a continuation of the disorder into adulthood (Wagner, 2001). Comorbidity As with all anxiety disorders, comorbid mental health disorders are common with GAD. More than one disorder is often diagnosed in an individual with severe anxiety. House (2002a) argued that in respect to anxiety disorders, “comorbidity tends to be the rule rather than the exception” (p. 66). Anxiety disorders are especially associated with the diagnoses of other anxiety disorders (Last, Strauss, & Francis, 1987). In particular, GAD is strongly associated with Separation Anxiety Disorder. Last, Strauss, and Francis (1987) discovered that of a clinicbased sample of children who were diagnosed with an anxiety disorder, one third met criteria for both Overanxious Disorder (now subsumed under GAD) and Separation Anxiety Disorder. In addition, depressive disorders are strongly associated with GAD (Last, Hersen, Kazdin, Finkelstein, & Strauss, 1987). Children and adolescents who suffer from both anxiety and depression have a significantly poorer long-term prognosis that youth with only anxiety (Pine, Cohen, Gurley, Brook, & Ma, 1998). Other common comorbid diagnoses of GAD include Attention-Deficit/Hyperactivity Disorder (ADHD) and Substance-Related Disorders (Rapoport & Ismond, 1996). Therefore, the presence of GAD in children or adolescents should prompt 12 clinicians to carefully assess for the existence of other anxiety disorder, mood disorder, and ADHD symptoms. Additionally, clinicians should make certain to evaluate for possible alcohol and other drug use in adolescents who present with GAD or anxiety symptoms. Assessment and Measurement Anxiety disorders can be more difficult to diagnose and assess in children as compared to adults because incomplete syndromes and symptoms of overlapping disorders may occur in addition to ordinary childhood fears and worries (Rapoport & Ismond, 1996). Also, the distinctions and subclassifications of anxiety diagnoses continue to be debated even in adults. In youth, assessment is difficult because children typically do not seek treatment on their own. Rather, parents must first recognize a problem and be willing to seek help for their child before an assessment will occur. In addition, accurate assessment of problems in chief emotional states, such as anxiety, is very difficult due to the necessity of creating suitable conditions that allow for accurate accounts of information and the limited ability of most young people to communicate about emotional states (House, 2002b). However, over the past decade, researchers have worked on the much-needed development and enhancement of several promising anxiety assessment instruments and guides for use with children and adolescents (Silverman & Ollendick, 2005). Multifaceted Assessment Due to its multifaceted nature, anxiety can be measured and assessed in several ways. It is important to assess physiological, behavioral, cognitive, and phenomenological aspects of anxiety across multiple contexts. Because we know anxiety causes physiological changes in the body, arousal may be measured and used as an assessment method for anxiety. Although several physical tension 13 measures have been used in laboratory settings, this technique is complicated because there is great individual variability in the physical response to anxiety (Kendal et al., 2004). Children and adolescents with GAD usually engage in avoidance and escape behaviors; therefore, a careful assessment of avoidant behavior, adaptive behavior, and social functioning should be completed (Greco & Morris, 2004). Since GAD’s defining characteristic is the cognitive aspect of excessive worry, an exploration of this facet is essential. Roemer and Medaglia (2001) noted that the assessment of GAD logically often begins with an investigation of cognitive worry. The subjective, phenomenological experience of anxiety can usually easily be measured and selfassessed in children and adolescents. Children can often learn to portray their subjective anxiety levels by using devices such as “fear thermometers” and other developmentally appropriate, analog reporting measures. Like adults, adolescents can be taught to use the Subjective Units of Distress Scale (SUDS) or other simple self-report scales used to depict personal levels of anxiety. Methods of Assessment Preferably, several methods of assessment should be used including interview, questionnaire, and behavioral observation and data should be collected from several sources such as parents, teachers, and peers (Greco & Morris, 2004). Clinical Interview. The interview is the most commonly used method to obtain clinical information about the client. By engaging in conversation, asking questions, and probing for information, critical information regarding the client, and the client’s emotional state and anxiety symptoms may be ascertained. 14 However, youths’ self-reports of emotional states during an interview may be limited because as mentioned earlier, children and adolescents often have difficulties communicating about their feelings. Children still may be learning how to successfully distinguish between different emotions and internal states, whereas adolescents still may be developing the appropriate language to express their feelings. Additionally, all youth may lack the drive to share their private inner experiences with an adult interviewer or clinician. During an assessment, the interviewer should be honest, direct, respectful, and humble in order to actively encourage the child’s or adolescent’s self-disclosure (House, 2002b). In addition, basic interpersonal skills (e.g., attention, acceptance, accurate empathy, unconditional positive regard, directed introspection, and feedback) will promote communication and further understanding. When talking with children about their fears and anxieties in order to assess or gain further understanding, examiners should do so with great tact and sensitivity that allows children to sustain their self-respect and sense of control. Normalizing the sense of anxiety and sharing similar personal experiences or experiences of other children can be quite helpful in promoting children’s willingness to reveal their own fears and anxieties. During the interview, the examiner can usually gain valuable information through the observation of the youth’s emotions (Kendal et al., 2004). Facial expressions, body language, affect, gaze, and emotional responses such as crying can be a rich source of data but should always be checked verbally with the child. When assessing for GAD, special attention should paid to any overt physical symptoms of anxiety such as muscle tension, jumpiness, or restlessness. Checklist Measures. 15 Checklist measures provide an additional means for evaluating anxiety in children and adolescents. Self-report measures for the assessment of anxiety are used widely in clinical and research settings (March & Albano, 1996). Self-report measures allow access to a vital source of information: a child’s internal experience. This important information is not readily observable and only available through the child’s introspection. A limitation of self-report instruments is that they have the attached complication of certain reading comprehension levels requirements. In addition, the measures are fixed, and further, supplementary information outside the generic inquiry is not gleaned. However, the fixed nature of the instruments is also advantageous for the purpose of objective norms, accessibility for experimental studies of validity and reliability, and the ease of use, saving both time and cost. Early self-report checklist measures for childhood anxiety typically characterized adult measures that had been altered for a younger population (March & Albano, 1996). These measures include the State-Trait Anxiety Inventory for Children (STAI-C; Spielberger, 1973), the Revised Children’s Manifest Anxiety Scale (RCMAS; Reynolds & Richmond, 1981), and the Revised Fear Survey Schedule for Children (FSSC-R; Ollendick, 1983). Greco and Morris (2004) noted that the current general consensus regarding these assessment instruments is that while they provide valid and reliable measure of distress, they lack discriminate validity and consequently confound anxiety with other common comorbid diagnoses. The push to create better assessment instruments that more usefully match up with the DSM-IV diagnoses led to the development of a new wave of childhood anxiety measures: the Multidimensional Anxiety Scale for Children (MASC; March et al.), the Screen for Child Anxiety Related Emotional Disorders (SCARED; Birmaher et al. 1997, 1999), and the Revised Spence Children’s Anxiety Scale (RCADS; Chorpita et al., 2000) (Moore et al., 2010). 16 The MASC is a self report measure that was developed to assess for clinical levels of anxiety in children and adolescents. Moore et al. (2010) declared the MASC to be “the gold standard of anxiety self-report assessment” (p. 633), and the measure has the distinctive asset of a harm avoidance scale and a validity index. The MASC has strong psychometric properties (Grills-Taquechel, Ollendick, & Fisak, 2008) and was developed by inventorying common worries in children and adolescents and then sampling the key symptoms to discover the most important anxiety symptoms and symptoms clusters. Thus, Moore et al. (2010) claimed that the MASC in effect characterizes the population factor structure of youth anxiety. The MASC is comprised of four major factors: physical symptoms, harm avoidance, social anxiety, and separation/panic anxiety. If the empirically derived factor structures are averaged across all four factors, they to a large degree match the DSM-IV-TR (American Psychiatric Association, 2000) diagnosis for GAD (Grills-Taquechel et al., 2008). In addition, single factors of the MASC also match the diagnostic clusters of separation anxiety disorder, panic disorder, and social phobia (Moore et al., 2010). The SCARED is another instrument that has strong psychometric properties (Birmaher et al. 1997, 1999). Similar to the MASC, the SCARED maps directly onto anxiety disorder diagnoses in the DSM-IV-TR (American Psychiatric Association, 2000). Another strength of this instrument is its sensitivity to treatment exposure (Muris, Mayer, Bartelds, Tierney, & Bogie, 2001). Both the MASC and SCARED include parent-report versions of the instruments. The parent-report versions allow for a more comprehensive examination of the child’s anxiety. Finally, the RCADS has several similar strengths as the SCARED (Chorpita et al., 2000) but has been examined and tested less in the research literature because it is newer than the other assessment instruments. Further research is necessitated to determine the distinctive 17 contributions and relative strengths of each of these newer childhood anxiety assessment tools (Greco & Morris, 2004). Behavioral observation. Behavioral observation data may be particularly revealing in the case of GAD but, alone, are not totally sufficient for diagnosis. Behavioral assessment can include both structured and unstructured observations (Kendall et al., 2004). Unstructured observations by a clinician can take place during the assessment sessions by noting any behaviors indicative of anxiety in the child. Parent and teacher reports of unstructured observations can also be gathered. Structured observations are performed by trained raters and involve direct observation of the child in a naturalistic environment (Kendall et al., 2004). However, this type of observation is seldom carried out and assessment instruments of observed behavior are rarely used (Greco & Morris, 2004). In addition, behavioral measures have yet to be normed and standardized. Applications to Therapy Cognitive Behavior Therapy For GAD and other anxiety disorders, cognitive behavioral therapy (CBT) is the most well-researched treatment and usually the treatment of choice due to the positive research evidence. Individual (e.g., Kendall, 1994; Kendall et al., 1997; Kendall, Hudson, Gosch, Flannery-Schroeder, Suveg, 2008), group (e.g., Barrett, 1998; Muris, Meesters, & van Melick, 2002; Cobham, 2003), and family-centered (e.g., Barrett, Dadds, & Rapee, 1996; Silverman et al., 1999; Rapee, 2000; Shortt, Barrett, & Fox, 2001; Lumpkin, Silverman, Weems, Markham, & Kurtines, 2002) CBT treatments have received strong empirical support for treating childhood anxiety. In fact, individual CBT, group CBT, and group CBT with parents have all been deemed 18 “probably efficacious” in the treatment of childhood anxiety disorders (Silverman, Pina, Viswesvaran, 2008; Flannery-Schroeder, 2004). CBT can be delivered in two modes: individual therapy and group therapy. Both forms use equivalent CBT interventions, but skills are simultaneously delivered to multiple people in a group format compared to one-on-one in an individual format. In addition, CBT can be childcentered (i.e., Child Cognitive Behavior Therapy) or involve the family/parents in the treatment process (i.e., Family Cognitive Behavior Therapy). Because childhood anxiety symptoms may be reinforced by features of parenting (Wood et al., 2003), parent-child attachment (Thompson, 2001), and maternal anxiety (Moore, Whaley, & Sigman, 2004), treatments involving the whole family may be beneficial and should be considered (Maid, Smokowski, & Bacallao, 2008). CBT Interventions. CBT focuses on modifying maladaptive behaviors and thought patterns and is comprised of several treatments and interventions. Several CBT techniques are commonly implemented in the treatment of childhood GAD, including relaxation training, exposure, and cognitive restructuring, which are discussed in detail below. It is important to keep in mind that when working with children and adolescents, clinicians must find creative and engaging ways to deliver skills to youth in order to prevent CBT from being dull and boring. Relaxation Training. The goal of relaxation training is to reduce general arousal. It also teaches children to become aware of the feeling of tension in their bodies and provides skills to decrease it. Because high level of general arousal and body tension are common features of GAD, relaxation training is a frequently used to treat individuals with GAD, including children and adolescents. Deep breathing, guided imagery, and progressive muscle relaxation (PMR) are three common 19 relaxation techniques used with children. The most empirically supported and commonly used method of relaxation is PMR (Eisen & Kearney, 1995). PMR involves the systematic tension and release of several muscle groups throughout the body. When using relaxation training with youth, developmental age of the child should be considered (Beidel & Turner, 2005). Young children have much shorter attention spans than older adolescents and adults. Therefore, relaxation directions and sessions as a whole should be shorter in duration when working with children. Relaxation sessions for adults can be at least 30 minutes in length, which is likely too long for young children (Beidel & Turner, 2005). In addition, children may have difficulty understanding the directions or not have the physical knowledge needed to tense a specific muscle area. In order to make relaxation understandable, engaging, and meaningful for kids, instructions should be provided using familiar visual images and objects. For example, Koeppen (1974) wrote a script containing instructions to “squish your toes down deep into a mud puddle” instead of simply directing kids to tense and relax their feet muscles. Other examples in Koeppen’s (1974) script include pretending to squeeze juice out of lemon to tighten hands and arms, stretch like a cat to tense arms and shoulders, and chew a big piece of gum to work the muscles of the jaw. Kids were also given images of a turtle pulling its head into its shell to focus on the neck and shoulder muscles and a fly on the nose to tense the nose and face. Clinician demonstrations of the various components are also helpful (Friedberg, McClure, Garcia, 2009). To learn relaxation, like any other skill, requires practice (Beidel & Turner, 2005). Therefore, one training or demonstration session is not sufficient for children and adolescents to obtain relaxation skills. Clinicians should encourage youth to practice these skills often between therapy sessions. Providing recordings of the training session, copies of scripts, and practice 20 checklists/reminders to the client and client’s family are some suggested ways to help children learn to relax and reduce arousal. Exposure Treatment. When treating a child or adolescent with GAD, exposure interventions should be considered. Exposure therapy involves exposing an individual to aversive stimuli for the goal of reducing the individual’s anxiety and/or avoidance of the stimuli. Exposure is one of the most commonly used techniques for treatment individuals with anxiety disorders (Eisen & Kearney, 1995). However, to perform exposure, the precipitating stimuli of the anxious reaction must be known. In GAD, clear stimuli may be difficult to discern due to the multiple number and often indistinct-nature of the stimuli present in this disorder; yet, in many cases, certain intense stimuli may be singled out and become an object of exposure. Exposure that is carried out in real situations is called in vivo exposure. For example, a child who worries about riding elevators may be directed to enter an elevator and ride it floor to floor. Another type of exposure that is often used in youth with GAD is imaginal exposure, which is conducted by imagining or visualizing aversive stimuli. This type of exposure can be used for almost any stimuli including social situations, unlikely occurrences, and physical sensations. For example, a child who worries about throwing up can be directed to imagine the sensation in detail using all senses repeatedly, until the anxiety aroused decreases. A common form of imaginal exposure involves writing a detailed story about anxiety-provoking stimuli. Then subsequent exposures can straightforwardly take place with readings of the story. Exposure procedures can either be carried out in gradual or sudden manners. Due to the intensity of elicited anxiety reactions, gradual exposures are generally desirable for many people, especially children (Eisen & Kearney, 1995). Children will likely be more willing to participate 21 in a therapeutic exposure intervention if they are gradually introduced to their fears beginning with stimuli that evoke low intensity arousal rather than starting with sudden exposure to their most feared stimuli. Furthermore, the gradual approach often allows the clinician and child to development greater therapeutic rapport and trust (Eisen & Kearney, 1995), and the child is able to develop confidence in his or her ability to overcome high-intensity fears with successful achievement over each low intensity stimuli. Systematic desensitization. Systematic desensitization, a type of gradual exposure based on classical conditioning that involves pairing feared stimuli with relaxation, has been found to be successful in the treatment of children and adolescents with generalized anxiety (Kane & Kendall, 1989). This form of exposure is one of the most frequently employed methods of treating childhood anxiety disorders (Silverman & Kearney, 1991). Systematic desensitization usually involves three steps: Relaxation training, construction of a fear/anxiety hierarchy, and pairing relaxation with exposure to hierarchy items. Children are first taught how to relax, most commonly using PMR (see above), in order to cope with the anxiety elicited during exposure. Next, a fear/anxiety hierarchy, which is a list of usually about 10 situations related to the aversive stimuli ranked in ascending order of anxiety-provoking intensity, is created in collaboration with the child. The final step involves pairing each item of the hierarchy (starting at the bottom, from least intense to most intense) with relaxation until the anxiety response is extinguished. Exposures may be imaginal, in vivo, or both. During exposures children rate their anxiety level using rating scales (e.g., SUDS or a 1-10 scale). When a child’s anxiety rating during an exposure is adequately low it is discontinued and the process continues with the next item on the list. If a child’s rating indicate the exposure is too 22 difficult to handle, then a clinician should withdraw to the previous item or create a midway step (Eisen & Kearney, 1995). Flooding exposure. Another main exposure technique for treating anxiety is flooding. Flooding is a type of exposure treatment that initially exposes a child to the most aversive stimulus in attempt to effectively extinguish the anxiety reaction. Usually, there are no preliminary steps to exposure such as relaxation training and anxiety hierarchies as in systematic desensitization. The client is exposed to the maximum arousing stimulus from the very beginning Eisen and Kearney (1995) do not recommend using flooding to treat children with severe anxiety or children under the age of 7 years. Flooding may be preferable in some instances in order to increase time and cost efficiency of treatment; however, there is little empirical research surrounding the success of flooding treatments on children with GAD (Eisen & Kearney, 1995). Cognitive Restructuring. Cognitive restructuring is another CBT method commonly-used to treat GAD. Using cognitive restructuring children are taught to examine their worries and replace the negative thoughts with positive statements. The first step of cognitive restructuring is to teach the youth to monitor his or her thoughts to identify cognitive distortions and understand the effects the distortions play on behavior. Then, the therapist teaches the child to replace dysfunctional thoughts with more adaptive thought patterns. Lastly, in a stance of guided discovery the child is encouraged to test their beliefs via exposure to reality in order to experimentally debunk faulty thought patterns and reinforce developing adaptive beliefs (Eisen & Kearney, 1995). Developmental variables should be considered before implementing cognitive interventions with children. As noted by Spence (2000), young children frequently have 23 difficulty with the cognitive component of CBT due to underdeveloped abstract thinking and introspection abilities. Therapists should present cognitive interventions in concrete and relevant manners to children such as using visual representations on an easel or chalkboard. Acceptance-Based Behavior Therapy. Recently, acceptance-based behavior therapy (ABBT) has been used to treat GAD in adults (Roemer& Orsillo, 2007; Roemer, Orsillo, & Salters-Pedneault, 2008). In two studies, Roemer and Orsillo (2007) and Roemer, Orsillo, and Salters-Pedneault (2008) focused on targeting experiential avoidance by using approaches intended to increase awareness and planned action in fundamental life areas. The authors focused on the premise that individuals with GAD negatively appraise their feelings, thoughts, and bodily sensations and then use worry as a way to avoid these internal experiences (Roemer et al., 2008). ABBT was used in these studies to directly target these problematic reactions and connections. In both trials, ABBT for the treatment of GAD in adults was found to be successful and promising, with significant reductions of GAD symptoms (Roemer & Orsillo, 2007; Roemer et al., 2008). Although, currently, ABBT has not been studied in children or adolescents with GAD, this form of treatment may generalize to a younger population; however, further investigation is needed. Similar types of acceptance and mindfulness-based interventions present in Dialectical Behavior Therapy (DBT) have been shown to be efficacious in treating a range of problems in children and adolescents (Callahan, 2008). Distress tolerance and self-soothing are DBT distraction and coping skills that may be particularly useful for anxious youth. Review of CBT Treatment Outcome Literature. As noted previously, CBT is the most well-researched treatment for childhood anxiety disorders; therefore, there are several empirical studies published exploring the efficacy of many 24 CBT programs and interventions, of both individual and group mode, as well as both childfocused and family-oriented forms. CBT has been found to be efficacious in treating childhood anxiety disorders (Kendall et al., 2004). Most childhood anxiety treatments are not aimed specifically to treat individual anxiety disorders but, rather, are usually used to treat a combination of disorders such as GAD, separation anxiety, and social phobia. Therefore, much of the data concerning GAD are intertwined with the data of other anxiety disorders, which can cloud the derived implications for GAD as an individual diagnosis. Individual CBT. Kendall (1994) compared a manualized CBT program to a wait-list control, in the first randomized clinical trial examining the efficacy of CBT in the treatment of childhood anxiety disorders, including OAD/GAD. Sixty-four percent of treated children were diagnosis-free of primary anxiety disorders at post-treatment, and gains were found to be maintained a full year following termination. Kendal et al. (1997) replicated these positive treatment outcomes and efficacy of CBT in the treatment of childhood anxiety in a second clinical trial. The CBT approach used in the above study is a 16-20 session manualized program for children (Kendall, Kane, Howard, & Siqueland, 1990) that incorporates behavioral techniques, such as relaxation, exposure, and role playing, with facets of cognitive processing. The program’s overall goal is for children to learn to identify their symptoms of anxiety, which they then use as prompts for utilization of anxiety management skills. The Coping Cat Workbook (Kendall, 1992) parallels the treatment sessions and provides exercises to facilitate child engagement and attainment of skills. Barrett, Dadds, and Rapee (1996) conducted a similar promising trial of individual child CBT but with the addition of a family management component. Anxiety-disorderd children were 25 randomly assigned to one of three groups: CBT, CBT with family management (CBT+FAM), or wait-list control. Compared to 30% in the control group, 60% of children in both treatment groups were diagnosis-free at post-treatment. Furthermore, after one year, 70% of children in the CBT group and 95% in the CBT+FAM remained free of their anxiety disorder diagnoses. Another CBT program designed for treating anxiety is children is the Preventing Anxiety and Depression in Youth (PANDY) program (Friedberg, Crosby, Friedberg, Rutter, & Knight, 1999). The program is designed to be engaging and appealing to children and uses playful applications such as experiential games, illustrated thought records, and videotapes that teach and model skills. Friedberg et al. (2003) discovered that the PANDY program resulted in symptom reduction in a small group of anxious children. Group CBT. Group therapy interventions are important in part because they maximize treatment costand time-effectiveness—two features that are gaining importance in current therapy for both clients and clinicians. Several studies have examined the efficacy of group cognitive-behavior therapy (GCBT) treatments for childhood anxiety disorders. Results have been very positive and promising. Barrett (1998) performed the first major study examining the efficacy of GCBT in treating childhood anxiety disorders. Results showed that in the treatment of childhood anxiety disorders, CBT interventions can be delivered as effectively in a group format as in an individual format. This initial study examined both types of GCBT in two treatment condition: child-only and family-based. At post-treatment, 64.8% of children across both treatment conditions were free of anxiety disorder diagnoses compared to 25.2% of children on the wait list. Furthermore, at the 12-month follow up, 64.5% of children in the child-only group were diagnosis free as well 26 as 84.8% of children in the family-based group. In respect to comparisons between the two treatment conditions, children receiving family-based GCBT showed marginal benefits on clinician ratings and self-report measures compared to the child-based GCBT. Several others studies examined the efficacy of family-based GCBT in the treatment of childhood anxiety. Silverman et al. (1999), Rapee (2000), Shortt, Barrett, and Fox (2001), and Lumpkin et al. (2002) all found family-based GCBT to be highly efficacious in generating and maintaining gains in the treatment of childhood anxiety disorders, similar to the results of Barrett (1998). Other studies have focused upon examining the efficacy of child-focused GCBT. Muris, Meesters, and van Melick (2002) and Cobham (2003) both found child-focused GCBT to be efficacious in reducing childhood anxiety. Furthermore, Cobham (2003) specifically aimed to explore the theory that anxious children with non-anxious parents need only child-focused GCBT treatments to produce reductions in anxiety rather than significant parental involvement. The results support the implication that children with anxiety disorders who have non-anxious parents only need child-focused GCBT to achieve significant treatment gains. However, one major question that remains in the literature revolves around parent involvement in GCBT for the treatment of anxiety. As Ben-Amitay, Rosental, and Toren (2010) explain, some models assert that anxiety in children may be propagated by parental and family dynamics. Therefore, involving parents in treatment may help discontinue those family dynamics and contribute to a decrease in anxiety. Barrett (1998) demonstrated early on in the literature that children receiving GCBT with family involvement showed marginally greater treatment gains than children in a child-focused GCBT. Several of the studies following this publication implemented a GCBT intervention with some sort of parent involvement. However, 27 as mentioned above, it has also been proposed and supported in the small pilot study by Cobham (2003) that anxious children with non-anxious parents do not need parental involvement in GCBT treatments to make treatment gains and reductions in anxiety symptoms. This area, including all types of questions surrounding parental involvement, evidently requires further investigation and attention in the future research. Technology Applications in CBT. Due to the efficacy of CBT in the treatment of anxiety disorders, multiple creative applications using technology have been developed for the assistance of training cognitive and behavioral techniques such as interactive computer programs and mobile telephone applications. Children and adolescents are great candidates for technological applications of GAD treatments. One technology-employing program described in Newman (1999) and Newman, Consoli, and Taylor (1999) utilizes palmtop computers and special software called, “The Stress Manager” in conjunction with regular therapy sessions in the treatment of GAD. This software was designed to be very user friendly and is comprised of several interactive curricula including selfmonitoring, imaginal exposure, cognitive restructuring, and relaxation training. The palmtop computer application has many advantages including the fact that it is easily portable, issues reminders for self monitoring and homework, can improve accuracy of data, reiterates important concepts, and allows for practice and application of CBT techniques between sessions in natural environments. In addition, the prompts and reminders issued by the computer may improve adherence to treatment. In a preliminary study, Newman et al. (1999) demonstrated that the computer program was effective in assisting the reduction GAD symptoms in adult participants. Although this program was not designed for youth, it could likely be successfully applied to adolescents. Some clients may be uncomfortable with the use of technology in their treatment; 28 however, youth typically are very at ease with computers and technology and will likely find this, and similar applications appealing. Another technology-based application that may be particularly useful for treating GAD in adolescents is the use of cell phones as an adjunct to CBT. Most cell phones can be programmed to set alarms that can act as prompts for self-monitoring or homework. In addition, Boschen and Casey (2008) suggested that text messaging technology can allow the exchange of information between client and therapist when other forms of communication are not convenient or feasible. For example, text messages can be sent to clients to act prompts or to therapists to report selfmonitoring data. Youth have widely adopted text messaging as a normal part of communication and will likely feel at ease with and attracted to this form of interaction. Furthermore, Boschen and Casey (2008) highlight photograph, audio, and video applications present on cellular telephones that may be used to assist in several potential therapeutic interventions for the treatment of GAD, especially exposure-based interventions. Clients can easily use their cell phone to expose themselves to pictures, sounds, or videos of feared stimuli during exposure homework exercises and even record themselves performing such tasks for review with their therapist. Finally, many mobile phones offer features such as Java, Bluetooth, and internet access that allow the translation of programs, transfer of data, and access to an incredibly vast amount of online information, respectively. These features can supplement and assist the therapeutic process. Family and Parent-based Treatment This section includes two types of treatments that are aimed at and involve the family and/or parents of a child with GAD (excluding family-based CBT treatment as it was covered in 29 the previous section). The two types of treatments are communications family therapy and contingency management/parent training. Communications Family Therapy. Although there is very little empirical research concerning communications therapy in treatment in childhood anxiety disorders, researchers have suggested that this form of family therapy may be effective. Communications family therapy addresses dysfunctional interactions and communication patterns within families that may be maintaining anxiety symptoms (Maid, Smokowski, & Bacallao, 2008). When anxiety is not elicited by certain contexts and is more diffuse (as is common in GAD), Nichols and Schwartz (2004) suggested that linear CBT strategies may be less helpful while more experiential approaches (e.g., communications therapy) may be more beneficial. This approach uses techniques such as role plays and sculpting to alter dysfunctional family roles that exacerbate anxiety in children. Contingency Management/Parent Training. Parents are very significant and influential in a child’s life. Consequently, when attempting to reduce worry in children, therapists often must work with the parents to change parental behaviors in order to achieve therapeutic goals. Parental training techniques that improve parental reinforcement and discipline methods can be used to proximally shape a child’s behavior (Eisen & Kearney, 1995). Therapists can also work with parents to improve avoidance, modeling of anxious behavior, support, and motivation. Although contingency management is most often used in the treatment of behavior disorders, the same techniques are also commonly used to reduce externalizing behaviors that often go with anxiety disorders (Eisen & Kearney, 1995). In many cases, parents may inadvertently reinforce anxious behaviors in their children (Morris, & Kratochiwill, 1983). For 30 example, giving worried children ample sympathy and attention or relieving them of household chores supplies positive or negative reinforcement for the dysfunctional worry. Contingency management is used to shift reinforcement to more adaptable responses, such as realistic beliefs, exposure, or relaxation. Multiple interventions are commonly used to meet these ends, including differential reinforcement, shaping, enhancing parent attention, command training, token economy, and time out (Morris, & Kratochiwill, 1983). Contingency management is not used as frequently as child-focused interventions in the treatment of GAD, but research has shown that this parent training technique can be constructive in treating childhood anxiety (Eisen & Kearney, 1995). Most studies demonstrating the usefulness of contingency management are in the treatment of childhood phobic disorders (Silverman, et al., 1999), school and social anxiety (Kearney & Silverman, 1990), and nighttime fears (McMenamy & Katz, 1989). Although little research has been devoted specifically to the efficacy of parental contingency management in the treatment of childhood GAD, many of the techniques are often applicable with this population. However, due to the lack of empirical support, Eisen and Kearney (1995) caution against the use of contingency management as the primary treatment in most childhood anxiety cases and instead advocate for its use in combination with child-focused interventions as discussed above. Play Therapy Play therapy is commonly used in the treatment of childhood emotional disorders (Eisen and Kearney, 1995). Play therapy can be conceptualized through several different theoretical orientations including psychodynamic, behavioral, and humanistic. Schaefer (1993) outlined several therapeutic factors of play therapy related to various orientations, including promoting 31 communication, overcoming resistance, relationship enhancement, fantasy, role-play, positive emotion, metaphoric teaching, and overcoming developmental fears. Lyness (1993) summarized therapeutic factors of play therapy that may be especially important in the treatment of fears and anxiety, including identification, repetition, projection, and denial. Children can use identification to better cope with anxieties by taking on a different perspective. For example, a child can take on the role of a protective super hero who watches over the house at night. Role-playing, imaginal exposure, modeling, and other CBT techniques can simply be incorporated into this play therapy strategy (Eisen and Kearney, 1995). Lyness (1993) described that repetition of play activities can help children overcome anxiety. For example, games like hide and seek can promote adaptation and reduce anxiety to environmental cues. This type of recurring play activity that allows a child to habituate to anxiety-provoking cues can be conceptualized as a form of exposure. Children can use projection to transmit their own embarrassing anxieties on play objects such as dolls, puppets, or stuffed animals. This can allow a child to assume the role of a confident protector of the play object rather than disclose anxious realities. Finally, Lyness (1993) explained that children can use denial to alter unpleasant characteristics of reality through play fantasies. Child’s coping skills can be improved if fantasy acts are similar to actual feared situations and played out in a gradual manner. This is play therapy techniques is comparable the CBT intervention of graduated imaginal exposure (Eisen & Kearney, 1995). Although play therapy may have a lot to offer in helping children overcome anxiety, play therapies used in the treatment of childhood anxiety have not been thoroughly and scientifically tested (Eisen & Kearney, 1995). Case studies focusing on reducing anxiety (e.g., GAD; Boston, Lush, & Grainger, 1991) have been published, but there is a severe lack of empirically supported 32 studies. Further research is required to establish the efficacy of play therapy in treating childhood GAD and other anxiety disorders. Pharmacological Treatment Early pharmacological treatment of anxiety in children utilized the benzodiazepine drug, alprazolam. Despite early indications of alprazolam’s benefits in the treatment of childhood anxiety, subsequently discerned negative outcomes, dose complications, and severe side effects have led researchers to suggest the use of benzodiazepines as solely a last alternative (Kratochvil, Kutcher, Reiter, & March, 1999). The pharmacological treatment of choice for childhood GAD and other anxiety disorders are selective serotonin reuptake inhibitors (SSRIs) (Beidel & Turner, 2005). Safety data have shown SSRIs to have minimal side effects and high tolerance levels (Kratochvil, et al., 1999). Two studies completed within the past decade have focused on studying the efficacy of SSRIs in the treatment of childhood GAD. Birmaher et al. (2003) demonstrated anxiety symptomreduction using fluoxetine in the treatment of 74 children with GAD and/or other anxiety disorders compared to a matching placebo. Significantly, 67% of the GAD-diagnosed children who were treated with fluoxetine were rated as being much or very much improved by the clinicians as compared to 36% of the placebo group. However, for the children with GAD, the symptom reduction found in the fluoxetine group did not convert into enhanced functioning measured by the Children’s Global Assessment Scale compared to the placebo group. In a trial ran by Rynn, Siqueland, and Rickels (2001) that included 22 children and adolescents with GAD as participants, results showed that participants treated with sertraline had significantly lower scores on ratings of severity and symptoms compared to those who received a placebo. However, this study had limitations surrounding the validity of the initial GAD diagnosis. 33 Overall, it appears that SSRIs may be effective in the treatment of childhood GAD, but further investigations are needed. Cultural Considerations and Relevance to Special Populations While the anxiety literature has given some consideration to cultural influences in adults, there is a deficit in cultural research on child and adolescent populations (Albano et al., 2003). Specific cultural symptoms and syndromes have not been explored in youth. For instance, isolated sleep paralysis, a phenomenon that is conceptualized as a type of nocturnal panic, has been found to be more prevalent in African American adults than in European American adults (Barlow & Durand, 1995). However, it has not yet been evaluated if this event also occurs in African American children (Albano, et al., 2003). The once common assumption that anxiety is experienced and expressed in similar ways across cultural groups has been challenged. Cross cultural researchers have made note that advances in emotion theory emphasize the role of culture in the expression and emotional experience of anxiety (Kirmayer, 1997). Although cross-cultural research has discovered analogous rates of the presence of anxiety disorders across the world (Horwath & Weissman, 1997), there does seem to be disparity in the experience, expression, and description of anxiety symptoms across cultural groups (Friedman, 2001). For example, Neal, Lilly, and Zakis (1993) compared fears of white children and African American children using scores on the Fear Survey Schedule for Children-Revised (FSSC-R). Although most fears were similar between the two groups, a notable difference was a lack of school and embarrassment-based fears in the African American children. In addition, Dong, Yang, and Ollendick (1994) used the FSSC-R to determine fears in Chinese children and adolescents and compare them to Western samples. The Chinese children reported greater social evaluative fears, such as test taking, and unlike Western 34 samples, older Chinese children (ages 11-13 years) reported more fears overall than younger children (ages 7-10). Despite the high anxiety rates in Chinese children, many Asian Americans have negative attitudes towards seeking help through therapy (Kim & Omizo, 2003). People in some Asian cultures feel elevated shame and stigma related to anxiety and other mental health disorders. External shame and social stigma of mental health problems is more prevalent in Asian cultures than White American culture. Typically, individuals of Asian cultures also disclose less, fear breaches of confidentiality, and tend to withhold pain rather than express it (Kim & Omizo, 2003). Friedman (2001) explains that in a simple sense, anxiety can be thought of as “a descriptive label for how one feels” (p. 38). Thus, what makes up anxiety is affected by numerous variables such as precursor occurrences, personal evaluation of these occurrences, self and others’ reactions to these occurrences, physiological reactivity, and the labeling of reactions by oneself and others. From a cross-cultural approach, people’s labeling of their reactions and feelings is reliant upon their societal reality and consequently is significantly different across cultures (Friedman, 2001). In sum, anxiety is comprised of multiple culture-dependent components, and perceptions of and reactions to this anxiety are greatly influenced by an individual’s cultural outlook. Therefore, because anxiety is so culture-bound, clinicians should be careful to gain a thorough understanding of how a client’s culture affects all aspects of his or her anxiety. Because anxiety is a complex construct whose expression seems to vary across cultural groups, anxiety can be difficult and complicated to assess across cultures. Using an anxiety assessment instrument on a cultural group for which it was not originally developed, requires 35 several important considerations. One chief difficulty is the language barrier and the process and results of translation. A general step for the cross-cultural translation method is to translate the instrument back to the native language in which it was created after translating to a new language to gauge if the original meanings held up. This back-translation method is necessary but not sufficient; Even this method does not eliminate all variations given that two different languages often do not have complementary words with identical meanings. Furthermore, if a cultural group embodies any unique expressions of anxiety, translated versions of assessment instruments will still fail to capture these culturally relevant expressions if the original tool did not screen for the specific behavior (Friedman, 2001). Another important issue to consider when assessing for GAD and anxiety across cultures is the client’s view of self. Different cultural groups vary in their view of self on a continuum ranging from egocentric to sociocentric (Kitayamu & Markus, 1994). Individuals from egocentric cultures, (e.g., many westernized societies) tend to view their identities as separate from society, whereas individuals from sociocentric cultures (e.g., traditional societies) tend to view themselves as part of the larger group. This cultural discrepancy in self-identity will undoubtedly affect the way language is used to express feelings such as anxiety. For instance, individuals from Western cultures may have no problems positively expressing the presence of anxiety on assessment instruments by endorsing items such as “I am anxious.” However, members of other cultural groups may ignore or falsely decline such questions because anxiety may be perceived as shameful to one’s self or family or equivalent ways of using language may not exist (Friedman, 2001). The overall research findings of the cultural influences on anxiety are varied and conceal any cohesive theory. There is an undeniably need for further comparative cross-cultural research 36 on the presence, conceptualization, experience, expression, and treatment approaches of GAD and other anxiety disorders in children and adolescents. The endeavor of understanding the role of culture in child and adolescent anxiety is only in its infancy (Albano, et al., 2003). Relevant Ethical and Professional Issues There are several ethical and professional issues that are relevant when treating children and adolescents with GAD. First, some issues arise when working with children and adolescents in general including confidentiality, the need for knowledge versus protection of child participants, and the stigma associated with the labeling of mental health disorders. In addition, ethical issues surround the use of exposure interventions in children with anxiety disorders. Confidentiality According to the American Counseling Association Code of Ethics (American Counseling Association, 2005), Section B and the American Psychiatric Association Ethical Principles (American Psychiatric Association, 2010), Standard 4, confidentiality is an important issue when working with any population; however, confidentiality can be complicated when working with minors because parents are entitled to information. As Lawrence and Kurpius (2000) expressed, confidentiality is a very difficult ethical and legal issue because a clinician has to decide what information to share and what not to share with a minor’s parents or guardians. In most cases, informed parental consent must be attained for a minor to enter treatment, and parents also have a legal right to the records concerning the evaluation and treatment of a minor. Clinicians also legally must break confidentiality for mandated protective reporting of child abuse/neglect and duty to warn against serious threats of injury. Despite the legally mandated protective reporting, there are three different stances regarding confidentiality a clinician may choose when working a minor: complete 37 confidentiality, flexible confidentiality, and no guarantee of confidentiality (Lawrence and Kurpius, 2000). Complete confidentiality excludes sharing any treatment information with parents but is often in direct conflict with the law. Conversely, no guarantee of or limited confidentiality, may deteriorate the foundations of trust in the therapeutic relationship leading to premature dropouts or reluctance to enter therapy once minors understand that parents have a right to information. A flexible approach to confidentiality allows adaptability to various situations but places the clinician in the vague, complicated process of trying to balance between legal and ethical rules. Lawrence and Kurpius (2000) recommend involving the parents in the initial meeting to create a mutual agreement concerning what specific information will be shared with them. This process is important because it creates clear boundaries and an agreement of trust between all three parties, which serves as an effective form of self-protection for the clinician. In addition, involving the minor in the decision-making process can strengthen therapeutic rapport. The Need for Knowledge Versus Protection of Child Participants Another relevant issue is the fact that there is a need for knowledge surrounding childhood disorders (especially anxiety disorders), but knowledge is limited by the difficultylevel of performing research on children. Knowledge regarding childhood disorders and treatment effects progresses slowly due to the protective, conservative approach society and researchers take when working with minors. Children need this protection because they are unable to defend themselves (Klin & Cohen, 1994). Consequently, studies are more difficult to achieve and researchers are more careful and take fewer risks when dealing with minors. However, a cultural aversion toward research in children may prevent valuable information from 38 being ascertained that could contribute to increased treatment effects and reduced suffering for children with mental health disorders. The two ethical principles, the need for knowledge and the protection of participants, come to a sharp dilemma when the subjects in question are children (Klin & Cohen, 1994). The cost and benefits must be examined and balanced. As, Klin and Cohen (1994) asserted, research and clinical practice with children should uphold the highest ethical standards; however, the field should not allow these principles to serve as a basis for inaction and ignorance. The Stigma Created by Labeling Youth with Mental Health Disorders An additional issue that should be taken into consideration when working with children is the stigma that is created when labeling a youth with a mental health disorder. Social distance, perception of threat, bias, distrust, embarrassment, and anger reflect the stigma surrounding children with mental health disorders and their parents (Martin, Pescosolido, Olafsdottir, McLeod, 2007). This stigma creates significant impairments for the child and the child’s parents/family (Hinshaw, 2005). Several investigations have revealed negative effects of labeling children with mental health disorders, and unfortunately, the individual must carry the label and face the associated stigma throughout his/her entire life (Hinshaw, 2005). Overall, the negative effects of the stigmatization of mental health disorders are severe and expansive. Because diagnosis is most often required for treatment, clinicians may fear that the given mental health label will cause just as many, or more problems throughout the child’s life as the treatment can improve. Given the negative effects of labeling, careful consideration should be given before diagnosing a child with a mental health disorder. As empiricallyvalidated treatments increasingly become more available, clinicians can more easily cite the benefits of providing a diagnosis— the evidence of effective treatments. This evidence of 39 treatment benefits may then outweigh the risks and potential negative effects of stigma created by the label. Exposure Interventions The use of exposure interventions creates some ethical issues because the goal of exposure is to temporarily increase the child’s distress. Friedberg and McClure (2002) acknowledge that some clinicians believe that exposure is unnecessarily upsetting to a child and consider the intervention risky. However, although exposure is uncomfortable in the short term, it has been found to offer long-term benefits (Friedberg & McClure, 2002). Exposure treatments are commonly-used and have been widely and successfully documented in the research literature (Eisen & Kearney, 1995). In other words, many researchers and clinicians argue that the temporary distress experienced by the child is worth it because of the significant improvements and eventual reductions in anxiety the treatment produces. Research Challenges and Needs A major challenge in the research of childhood GAD is a general lack of differentiation between anxiety disorders. Most research combines multiple anxiety disorders in the investigations, which clouds the results and useful conclusions that can be deduced related to individual diagnoses. To facilitate the advancement of knowledge about childhood GAD, research needs to quit treating anxiety as though it is a single disorder. Continued study is important regarding the treatment of childhood GAD. As mentioned above, most childhood anxiety treatments are not aimed specifically to treat individual anxiety disorders but, rather, are usually used to treat a combination of anxiety disorders, often including at least GAD, SAD, and SOP. Therefore, further research on the efficacy and effectiveness of therapy for treating GAD as a single disorder is necessary. However, due to high comorbidity 40 rates, GAD rarely occurs in isolation. Consequently, future research should also be dedicated to the treatment of GAD as it usually presents in practice– in conjunction with comorbid diagnoses (e.g., depressive disorders and other anxiety disorders). Additional research on the efficacy of exposure treatments on childhood GAD is warranted. There is a distinct lack of literature devoted to the use of flooding techniques on children with GAD. Although evidence has indicated the efficacy of systematic desensitization in treating this population (Kane & Kendall, 1989), it is not yet clear whether exposure treatments alone generate desired improvements (Eisen & Kearney, 1995). The scientific research literature concerning play therapy in the treatment of GAD also is severely deficient. Case studies comprise almost all literature concerning play therapy with anxious youth. Consequently, play therapy needs to be tested through rigorous empirical research means in order to establish any efficacy in the treatment of anxiety-laden children. Furthermore, research concerning the pharmacological treatment of childhood GAD is needed. Although SSRIs are considered the standard pharmacological treatment for this population, evidence supporting this notion is somewhat limited. Most research regarding pharmacological treatment includes participants of mixed diagnostic anxiety diagnoses, which, again, leads to difficulty understanding how the conclusions directly relate to GAD. Overall, concerning the efficacy of therapy on childhood GAD, future research would benefit with the selection of singular primary GAD diagnosis in participants as well as increased sample sizes, further measures of improvement, and long term follow-ups (Beidel & Turner, 2005). Silverman, Pina and Viswesvaran (2008) suggested several directions for future research concerning the treatment of childhood anxiety disorders. These suggestions include moving beyond using waitlist control conditions to using active controls, such as pill and psychological 41 placebos or other established treatments. This action can help to promote CBT to the status of “well-established” treatments. Other suggestions for research studies include increased focus on developmental issues, integrated pharmacological treatments, and increased minority representation. Another area in which further research is needed surrounding childhood GAD is the epidemiology and etiology of the disorder. As suggested by Costello, Egger, and Angold (2004), studies should begin looking at the individual anxiety disorders with different manifestations in relation to different ages and other disorders, correlates, and risk factors. Also, further exploration of genetics, cognitive patterns, parenting styles, early experiences, and temperament is warranted regarding the etiology of childhood GAD. Methodological Issues Finally, recommendations for methodological “best practices” in future research are discussed below. First, there is a need for long-term longitudinal follow-ups of treatment efficacy studies to track treatment effects over time. Also recommended for future treatment efficacy studies is the use of extensive, well-rounded measures of severity and improvement, such as diagnostic symptom criteria, clinician ratings, as well as child and parent self-report measures. Furthermore, across all areas of childhood GAD research, increased sample sizes are recommended to enhance statistical power of results, and lastly, the use of multiple sources of data is recommended in research concerning the assessment of childhood GAD. Conclusion Generalized Anxiety Disorder in children and adolescents is a widespread, debilitating disorder. The disorder is characterized by excessive worry and physiological arousal symptoms and is often accompanied by comorbid mental health disorders, most commonly other anxiety 42 disorders and depression. Assessment and measurement of GAD in youth can be challenging but is aided by the use of a multifaceted approach and assorted methods of assessment (e.g., clinical interview, checklist measures, and behavioral observation). CBT is empirically validated and the most commonly-used treatment for GAD in children. Both individual and group CBT formats are efficacious and focus upon altering behavior and thought patterns by implementing relaxation, exposure, and cognitive restructuring. Family- and parent-based treatments are other interventions used to treat childhood anxiety that focus on improving family communication and parental reinforcement and discipline techniques. Although there is little empirical evidence addressing its efficacy, play therapy is another method used in the treatment of childhood GAD. Finally, pharmacological treatments, mainly SSRIs, have been found to be successful in the treatment of GAD in children and adolescents; however, additional research is necessitated in all treatments modes. Cultural considerations involving GAD in children include cross-cultural differences in the manifestations of anxiety and self views. In addition, ethical issues concerning confidentiality, protection of minors, stigma, and exposure interventions are present when working with this population. Lastly, a great deal of additional research covering all aspects of GAD in children and adolescents is needed. References Albano, A. M., Chorpita, B. F., & Barlow, D. H. (2003). Childhood anxiety disorders. In E. J. Mash & R. A. Barkley (Eds.), Child psychopathology (2nd ed., pp. 279-329). New York: Guildford Press. American Counseling Association. (2005). 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