Rosmarinus officinalis – the three chemotypes
Transcription
Rosmarinus officinalis – the three chemotypes
Rosemary Essential Oil Profile - Rosemary Rosemary Rosmarinus officinalis – the three chemotypes chemotypes,1 therefore it is important to know the specific qualities of each type. Rosemary has been praised and even venerated since earliest antiquity, and branches of it have been found in Egyptian tombs dating back to the First Dynasty (about 3000 BC). This chemotype of Rosemary is the most commonly used in Aromatherapy. Rosemary CT 1 is reported by French ‘Aromatic Medicine’ physicians as the most specific for neuromuscular problems, such as muscular aches, cramps and spasm; neuralgic and rheumatic pains 2, 3, 4, 5, 6, 7, 8 and as a general "tonic", warming and energising for memory and concentration problems, fatigue states and recovery from illnesses. 2, 10, 11 Rosemary CT 1 is also seen as a digestive stimulant useful for the liver and gall bladder, mucolytic and decongestant for respiratory conditions and useful for skin and scalp conditions such as acne, mature skin, dandruff and hair loss. 2, 13, 14 Over time, the therapeutic reputation of Rosemary grew until it became legendary. It was Arab physicians, such as Avicenna, who first managed to extract its essential oil, which was subsequently much valued by the alchemists and physicians of the European Renaissance. From the 17th century, Rosemary was a popular herb and essential oil in European medicine, with praises accorded to it such as: "The spirits of the heart and entire body feel joy from this drink, which dispels all despondency and worry" (Wilhelm Ryff), and useful for "… all cold diseases of the head and brain, as the giddiness or swimmings therein, drowsiness or dullness…, the dumb palsy, or lack of speech, the lethargy and falling-sickness (epilepsy)" (Nicholas Culpeper). "Rosemary" is derived from the Latin ros (dew) and marinus (sea). "Sea dew" alludes to its preferred habitat on sea coasts. An undemanding plant, Rosmarinus officinalis grows all around the Mediterranean region. Extraction The essential oil of Rosemary is extracted via steam distillation of the branches for approximately 1 hour, 30 minutes. All three of the Rosemary chemotypes come from sustainably harvested wild-growing plants. A carbon dioxide extract is also produced. A Rosemary CO 2 extract, utilising Rosemary CT 2 cineole, is the basis of our Amiox antioxidant. What is a Chemotype? In aromatic plants, a chemotype refers to a plant of a defined species, where it can produce an essential oil of varying composition (and hence, therapeutic activity). This is specifically a genetic variation, that is often originally determined by the conditions under which it was grown, such as climate, latitude, altitude and the quality of the soil. Chemotypes can be seen in seen in distinct geographical areas, as is the case with Rosemary, or there can be dramatic differences between plants growing right next to one another, as is the case with various Meleleuca and Eucalyptus species. A variety of aromatic plant species will produce different chemotypes, notably species such as Thymus vulgaris (Common Thyme), Melaleuca quinquenervia (Niaouli), Matricaria recutita (German Chamomile) and Rosmarinus officinalis (Rosemary). Three different chemotypes (CT) of Rosemary are found. Details of the composition of the three chemotypes are below. As can be seen, there are marked differences in the composition of these three Rosemary CT1 camphor from Spain Rosemary CT2 1,8 cineole from Morocco This chemotype is reported to be the most specific for respiratory and ENT (ear, nose and throat) ailments, such as colds, ‘flu, bronchitis, asthma, ear infections and the like, with it’s expectorant and mucolytic properties. 15, 16, 17, 18, 19, 20 Rosemary CT2 is also considered a useful analgesic oil, for conditions such as headaches and the pain of rheumatoid arthritis; a circulatory tonic for venous circulation. 21, 22 Rosemary CT3 verbenone from France (Corsica) This special chemotype (found only in Corsica) is reported to be the most specific for liver and gall bladder complaints, as indicated by poor digestion, difficulty with fatty foods, constipation and the like. 23, 24, 25, 26 Rosemary CT3, with it’s gentle mucolytic properties, is also considered useful for respiratory and genital complaints (such as in the case of vaginal discharge). 27, 28 French "Aromatic Medicine" specialists have suggested this chemotype as a useful immunostimulant, as a cardiotonic as in the case of heart palpitations, for nervous and post-natal depression, and generally as a restorative of psychological balance. 29, 30, 31 Safety Issues Rosemary CT1 and CT3 should used with care on epileptics (especially when poorly controlled) and in cases of high fever, due to the potentially neurotoxic quality of camphor.32, 33 This caution is most specifically for the ingestion of the oil.34 Always use diluted; Rosemary oil is classed as a "weak" sensitiser and can potentially create allergic skin reactions in hypersensitive individuals.35 In respect to any skin irritant qualities, Rosemary oil is classed as "very mildly irritant". 36 Due to the content of 1,8 cineole and camphor in all three of the chemotypes, Rosemary oil does have the capacity to poison young children, if ingested in large amounts (a potentially fatal dose of Rosemary CT1 could be as low as 5mL in a small child).37 Compound CT1 Camphor CT2 1,8 Cineole CT3 Verbenone Camphor 1,8 cineole a-pinene verbenone bornyl acetate 15 -30% 17-25% 18 -27% trace trace 7 -15% 40 -55% 8 -17% trace trace 5 -15% 6 -22% 15 -38% 5 - 40% 1-10% Always keep out of reach of children and the use of bottles with ‘dropper’ inserts will help to limit accidental ingestion. Rosemary essential oil has often been mentioned in Aromatherapy books as an oil not to be used during pregnancy nor in high blood pressure conditions. However, there is no evidence to support such statements. The use of Rosemary oil in typical external applications (in baths, in diffusers and up to a 2.5% dilution for a full body massage) is considered to be non-problematic in such cases.38,39,40 With external applications of less than a 10% concentration, Rosemary oil of any chemotype can be considered as non-toxic, non-irritant and non-phototoxic.41, 42, 43 References available on request from Essential Therapeutics Rosemary Times Three Offer! Enjoy a 10% discount on two Rosemary essential oils until 16th May, 2003. Rosemary CT1 – 10mL Rosemary CT2 – 10mL And while stocks last, we are offering our certified organic Rosemary CT 3 verbenone in both 5mL and 50mL at 15% off. Coming soon to a distributor near you… In the coming months, we will receive our first batch of AUSTRALIAN GROWN Rosemary CT 3 verbenone. It is being grown in plantation in western Victoria. Our first samples show it to be an excellent oil. It is being grown organically, but the farm is not yet certified. We will keep you informed… The Ultimate Practitioner Range For your nearest Distributor, please contact: Essential Therapeutics Head Office 2/58 Melverton Drive, Hallam VIC 3803 Tel (03) 8795 7720 Fax (03) 8795 7375 Email [email protected] Victoria – Oborne Health Supplies Tel (03) 8831 3888 Fax (03) 8831 3898 South Australia - BettaLife Distributors Tel (08) 8351 8455 Fax (08) 8351 8722 New South Wales - Select Botanicals Tel (02) 9817 0400 Fax (02) 9817 0500 Western Australia - Olfactory Sensations Tel (08) 9470 9770 Fax (08) 9470 9766 Queensland - Sunstate Therapy Supplies Tel (07) 5493 6555 Fax (07) 5493 6566 Queensland - Naturopathic Remedies Group Tel (07) 3261 8988 Fax (07) 3261 7355 Tasmania - Cartledge Agency Tel (03) 6344 5466 Fax (03) 6343 2472 Northern Territory - Kay Halstead (Agent) Tel 0428 898 410 New Zealand - Wellpark College Tel 9360 0560 Fax 9376 4307 Minneapolis USA - Michelle Juneau Tel (612) 332 4422 Fax (612) 344 1282 Seattle USA – Zobiana Aromatherapy Tel (360) 658 4908 Email [email protected] Hong Kong - Southern Essence Tel (852) 9833 9883 Fax (852) 2906 5291 Vol 12 April 2003 Editorial Quality Matters… Greetings. How can you be certain that you are purchasing a real essential oil? In this issue we expose the ‘well kept secret’ of our unique Quality Assurance program – Quality Matters… Based on numerous queries, included is an in-depth review of the Three Rosemarys’ to help allay confusion over ‘which oil is best?’ We have ‘relaunched’ our Essential Base Lotion with a new formulation and pricing. I am sure you’ll agree that this natural base lotion is a better alternative the usual mineral oil-based Sorbolene lotions. In parting, given the times, we all wish you peace! Best Regards, Ron Guba Editor New! Virgin Red Rose Hip Oil Essential Therapeutics has long offered a top-quality refined Rose Hip oil, a great ‘EFA’ oil (rich in essential fatty acids) for skin regeneration. We do love virgin, or unrefined vegetable oils, but the unrefined Rose Hip first available was far too ‘smelly’ and dark in colour. We have now sourced an excellent Virgin Red Rose Hip oil (Rosa rubinginosa or mosqueta) from Chile. It is light red in colour, with a pleasant odour. Coming soon to our distributors, this Virgin oil is what we will now be offering. Special Introductory Offer Our new Essential Base Lotion will be offered until 16th May, 2003 at a 10% discount off the normal wholesale price of both the 250mL size and 1 litre size. And if you would like a free 100mL trial sample, please contact your nearest distributor. If one looks at herbal medicine products out in the marketplace, we see almost exclusively products that are listed with the Therapeutic Goods Administration and are guaranteed in their quality. That is, the products actually contain what they claim to contain! The whole plethora of ‘Aromatherapy’ products, on the other hand, does present a different picture. Many of the products available to the public are ‘life style’ products that use the concept of ‘Aromatherapy’. As no particular therapeutic claim is being made (even though it may be implied), the ingredients contained may be real essential oils, or adulterated essential oils and synthetic fragrance compounds. This is simply the reality of consumer products that exploit the popular ‘feel good’ idea of Aromatherapy. More to the point, however, are the availability of so-called ‘essential oils’ from companies that are happy to promote their products as ‘100% Therapeutic-grade Aromatherapy Oils’ to unsuspecting complementary therapists and health care facilities, along with the general public. In this, the loophole is that no therapeutic claims are made for the products. Hence, the essential oils can be promoted as ‘100% pure & natural’, without ever having to pass ANY quality control standards, such as is demanded by the ‘Good Manufacturing Practice’ standards of the Therapeutic Goods Act. The actual quality of such products has been demonstrated to be from ‘OK’ to highly adulterated. Such adulteration varies from extension with less expensive essential oils; extension with synthetically produced aromachemicals and/or dilution with solvents such as dipropylene glycol or diethyl pthlatate. You might even be provided with a ‘certificate of analysis’, that quite truly is not worth the paper it is printed on. Let the buyer beware! When it comes to the true therapeutic uses of essential oils, quality DOES matter. I’d like to discuss with you what we at Essential Therapeutics do to actually guarantee the authenticity of each and every essential oil that we provide. Our Quality Assurance Department Back in 1991, John Fergeus, our MD, acquired our first gas chromatography / mass spectometry unit. GC/MS analysis (I’ll use the abbreviation), combined with other standard physical tests, is simply the state-of-the-art method for analysing essential oils for authenticity. However, having this equipment is not enough by itself. John Fergeus and our other QA staff have spent countless hours of study, attending trade conferences, etc., etc. to specifically become expert in the analysis of essential oils. In other words, simply to send a sample of an essential oil out for analysis to a company or University who will do simple gas chromatography or GC/MS analysis, may very well not be fruitful. Unless the staff are real experts in essential oil analysis and up-to-date with all the possible While stocks last. © Copyright 2003 Essential Therapeutics Not for Public Distribution continued overleaf aspects of adulteration, you will likely only receive some identification of major components. essential oil analysis and product development. Quality Assurance Procedures: Hence, a Lavender oil sample may be shown to meet the ‘B.P.’ standard (British Pharmacopoeia), with appropriate levels of linalool, linalyl acetate and camphor as prime components, as well as basic physical tests. The oil can then be passed off as ‘real’ Lavender oil, even perhaps being supplied with a ‘certificate of analysis’. A diagram is on the following page of the procedures and analysis that every essential oil that we provide must go through. It must be said that we have longstanding relationships with our major producers. They do not provide us Dr Charles Cornwell conducting GC/MS analysis with adulterated essential oils! distilled’ essential oils and oils that have Certainly, our quality assurance program been subject to short time ‘perfume’ will always ‘keep them honest’, should it distillation. With hexane-extracted ever become an issue. absolutes, such as Rose and Jasmine, they More to the point are wannabe suppliers, are guaranteed to be ‘clean’, with less than who provide us with samples of essential 10 parts per million (that’s less than oils they wish to offer us. In this situation, 0.001%) of any hexane residues. our QA testing has demonstrated Growing Method. An important and adulteration on various occasions. Such unique aspect of our TGEO Quality results settle the matter very quickly. Guarantee is to provide the growing Further Therapeutic Grade Essential Oil method for each essential oil. (TGEO) Guarantees Select essential oils are the best quality, Decidedly, our extensive Quality 100% pure & natural essential oils derived Assurance program is unique amongst from conventional agriculture. One Aromatherapy suppliers. Our procedures example is Bergamot ‘Supreme’ oil, fully meet and surpass all the requirements of expeller-pressed from selected quality fruit the Australian Therapeutic Goods from Calabria in Italy. Administration and the necessary Good Traditional essential oils are from ‘nonManufacturing Practice standards. certified’ organic growing practices. That Above and beyond the TGA standard, we is, pesticides, synthetic fertilisers and the offer you further assurances on each like are not used, but have not been essential oil that we provide: certified by an organic certifying association. One example is Patchouli oil, Defined Botanical Species. The sourced from small-scale farmers in Aceh Therapeutic Goods requirements do demand that the exact botanical species be province, Indonesia. to be used. However, we have seen that Organic essential oils are guaranteed to be this requirement can be bypassed, as a from certified organic growing practices simple analysis to meet a ‘standard’ leaves (how easy it is to pass off a poor quality oil room for the blending of oils from less as ‘organic’!). We hold a certification expensive species, as in the case of number (W310) from the Biological Lavandin and True Lavender. We make Farmers of Australia (BFA), allowing us to certain that we provide you the exact offer fully certified organically grown botanical species as stated. And further, essential oils. In this case, every oil we where necessary, we also state the import that holds overseas organic chemotype, as in the example of certification is vetted by the BFA to Rosemary CT1, CT2 and CT3. In each case, guarantee its certification.This certification the species is Rosmarinus officinalis, but can apply both to plantation grown plants, each chemotype has a different essential such as our organic True Lavender, and to oil composition and hence, a different wild-harvested plants, such as our Tea range of therapeutic benefits. Tree ‘Ecowild’. Country of Origin. A number of Wild essential oils are derived from wildaromatic plants have their natural, harvested aromatic plants. Such essential ‘vintage’ ares of growth. For example, True oils generally represent the highest quality Lavender clones are grown in a number of and excellent value, as compared to the countries, including Australia, but the higher costs of plantation-grown, certified ‘truest’ True Lavender, wild-harvested organic plants. As well, we look to source Alpine Lavender, is sourced only from sustainably wild-harvested plants. Prime higher altitudes of the Provence in examples include Rosemary CT 1 from Southern France. We state the country Spain and Eucalyptus Australiana from of origin for each essential oil. New South Wales. Extraction Method. We state the In summary, real quality does matter. extraction method for each essential oil – Our commitment and passion is to provide either steam distillation, carbon dioxide you with the highest quality essential oils extraction or hexane extraction for true therapeutic use. Our TGEO (absolutes). In the case of steam Quality Guarantee is simply the most distillation, we specifically source and comprehensive assurance available! supply single distilled oils that have been For further information, please ask for a distilled for the full length of time. We copy of our Quality brochure. avoid offering ‘rectified’ or ‘double- However, upon closer inspection (which we have done many times on Lavender samples), one may very well find on GC/MS analysis, trace amounts of compounds such as dihydro linalool. Detection of such a compound is a sure sign that the oil is a ‘blend’ including synthetically produced linalool – the dihydro linalool is a by-product of synthetic manufacture, never found in a True Lavender oil. We have developed an extensive ‘constituent library’, giving us the capability to detect even the most ‘sophisticated’ adulteration for each and every essential oil that we provide. Therefore, without expert analysis, ‘essential oils’ can be demonstrated to meet various standards (B.P., ISO, AFNOR) relating to chemical composition, yet be quite adulterated. As well, the demand for guaranteeing species purity is routinely disregarded by flavour & fragrance suppliers. That is, True Lavender should be exclusively from Lavandula angustifolia, not hybrid Lavandin, L. intermedia. Hence, it becomes an issue of what level of adulteration can be ‘gotten away with’. Hence, an essential oil can meet all the Australian TGA/GMP standards and be ‘passed’ to be promoted as a ‘therapeutic’ product, yet be an inferior, adulterated essential oil. It is our in-depth analysis and our long-term relationships with distillers that allow us to fully guarantee our oils. Most importantly for our customers, we do not depend on ‘out sourcing’ our product analysis to other companies. We have a dedicated, expert Quality Assurance team that fully analyses and guarantees every essential oil that we offer. Our Quality Assurance team: Dr. Charles Cornwell PhD. Charles is our Chief Chemist, responsible for all aspects of GC/MS analysis and product development briefs. His Doctorate (and expertise) is specifically in the chemistry and analysis of essential oils. Linda Groom B.Eng. Linda is our Quality Assurance Manager, responsible for all aspects of QA issues, including all regulatory issues (such as Therapeutic Goods requirements). Claire Caldere Dip. Chem Science Claire is our Quality Assurance Technician, who has been with us for almost nine years. Claire is responsible for assisting in all aspects of Quality Assurance, including New & Improved! Essential Base Lotion The natural alternative to ‘Sorbolene’ lotions… We have just ‘upgraded’ our Essential Base Lotion – a new formulation, new packaging and a new lower price! Essential Base Lotion is a natural vegetable oil-based product, designed to be an alternative to the ubiquitous mineral oil-based ‘Sorbolene’ lotion. It is a lighter, easily-absorbed version of our popular Essential Base Cream. For years, various books have recommended and practitioners have used mineral oil-based ‘Sorbolene’ lotion and ‘aqueous creams’ either by themselves, or as a ‘carrier’ for the addition of essential oils, herbal extracts, etc. for topical applications. Though some dermatologists still suggest that Sorbolene-type lotions are the best moisturisers available, many of us must disagree. This recommendation is based on the fact that mineral oil and petroleum jelly (both derived from crude oil) are very occlusive compounds on the skin. That is to say, they act like plastic cling wrap. They smother the skin, retarding the loss of water vapour from the skin and restrict ‘skin breathing’ - the transpiration of oxygen and carbon dioxide. ‘Mineral oils’ are very inert compounds – simple hydrocarbons, compounds not present in our own ‘skin oil’ or sebaceous secretions. These compounds simply sit on the surface of the skin, and are not utilised by the skin cells in our epidermis. Mineral oil provides no real moisturising properties. There are further drawbacks to mineral oil-based creams and lotions. Mineral oil tends to clog the sebaceous glands, potentially leading to blackheads and acne. Indeed, mineral oil can even lead to a reduction in our own sebaceous secretions, causing dry skin! As well, most Sorbelene lotions utilise common synthetic emulsifiers and synthetic preservatives - all with their own draw backs. In contrast, the natural vegetable oils and other emollient ingredients in Essential Base Lotion have a host of benefits for the skin. These ingredients closely mimic our natural sebaceous secretions, are far less ‘occlusive’ than mineral oil and do increase hydration of the skin. A far better alternative! Essential Base Lotion makes an excellent carrier base for use in all types of applications, including Aromatherapy treatments, massage, reflexology and podiatr y. Like Essential Base Cream, Essential Base Lotion can be used as a general moisturiser for the body, face and hands as is, or as a ‘carrier base’ for the addition of pure essential oils. Just add any desired essential oils and mix in well. Up to an additional 10% essential oils can be added. Therapeutic Grade Essential Oil (TGEO) Guarantee Essential Base Lotion is well suited for use in health care settings, such as hospitals and nursing homes as an effective general moisturiser – for both patients and staff. Especially for nursing home residents, where ‘skin integrity’ is a common problem, Essential Base Lotion will offer real, noticeable benefits with daily use. Essential Base Lotion now contains the following ingredients: Pure water and vegetable oil-derived glycerine. Natural emollients: Pure expeller pressed Sweet Almond and Macadamia oil, light Coconut oil fractions, Cocoa Butter and Mango Kernel Butter. Emulsifiers: Vegetable oil derived emulsifying wax and sorbitan stearate (a natural, food grade emulsifier from palm oil). The lotion is protected against rancidity by using our Rosemary antioxidant, Amiox and against microbial growth using our natural Grapefruit Seed extract, Citricidal. Linda Groom (on the left) and Claire Caldere (right). Feedback... Any questions for the editor? Would you like to see an article on a particular essential oil? Would you really like for Essential Therapeutics to offer some new product ideas? Please direct your ideas and comments to us here at Head Office or on [email protected]. We look forward to hearing from you. Essential Base Lotion is now in available in two sizes, a 250mL ‘squeeze’ bottle and a 1 litre pump dispenser, both excellent to prevent any cross contamination when used in health care settings. Both sizes are now packed in opaque white bottles to help prevent rancidity. New prices: 250mL for $10.00 1 litre for $33.00