How to use ReFissa

How to use ReFissa® Tretinoin Cream, USP (Emollient) 0.05%
To get the full effect of ReFissa, use it for at least 24 weeks.
STEP
STEP
1
2
Each night, gently wash
your face with a mild soap
or cleanser and pat dry.
Let your face dry for
20 to 30 minutes before
applying ReFissa.
STEP
STEP
3
4
Squeeze a pearl-sized
amount (1/4” in diameter) of ReFissa onto your
finger.
Dot ReFissa onto cheeks,
forehead, and chin. Spread
evenly. Avoid the eyes and
the skin around the ears,
lips, and nostrils.
What to expect month by month.
0-1 As ReFissa begins to work, it may produce redness, flaking, and
irritation. Many people find t he signs of irritation end after a
couple of months. If your skin becomes too irritated, consult
with your doctor, who may suggest you try using it every other
night. Then resume nightly treatment when you can.
1-2 You may notice that skin is smoother and has a softer texture.
3-4 Irregular pigmentation may begin to lighten, while fine facial
wrinkles may begin to diminish. You may see an overall improvement in the texture and appearance of your skin.
You may continue to see and feel your skin texture and skin
tone improve.
6-12 Continue to use ReFissa nightly and apply sunscreen daily (SPF
15 or higher).
Try these skin care tips while using ReFissa®.
Maintain your current skin care program of soap or cleanser
and daily sunscreen.
Continue your usual makeup routine.
Avoid the sun (including sunlamps) and always use a sunscreen
(minimum SPF 15) when outdoors—even on a cloudy day.
Avoid hair and face products that contain alcohol, astringents,
menthol, spices, or lime. These ingredients may irritate your
skin.
Avoid using electrolysis, hair depilatories, or waxes on your
face.
Keep hair dye or permanent-wave solutions off your face.
All of the information on this card and more is
available at www.refissa.com and in the comprehensive
Patient Booklet included in the Patient Starter Kit.
The Fine Wrinkles Retinoid
ReFissa 0.05% is indicated for mitigation (palliation) of fine facial wrinkles, mottled
hyperpigmentation, and tactile roughness in patients who use a comprehensive skin
care and sunlight-avoidance program (including sunscreen).
ReFissa does not eliminate wrinkles, repair sun-damaged skin, reverse photoaging,
or restore more youthful or younger skin.
Do not use if the patient is taking drugs known to be photosensitizers, pregnant,
attempting pregnancy, or nursing. ReFissa, early in treatment, may cause redness,
itching, burning, stinging, and peeling. If the degree of irritation warrants, patients
should be advised to use less medication and decrease the frequency of application.
If still significant, patient should be advised to discontinue use.
Please see full prescribing information.
ReFissa is a registered trademark of
Suneva Medical, Inc.
© 2013 Suneva Medical, Inc. All rights reserved. SM 1321-34 REV00