CALL FOR PAPERS Bioinorganic Chemistry and Applications Special Issue on

Bioinorganic Chemistry and Applications
Special Issue on
Bioactivities of Organotransition Metal Complexes
including Metallocene
CALL FOR PAPERS
During the last thirty years, the chemistry of organotransition metal complexes
has continued to experience explosive growth in novel substances, new reactions,
surprising mechanisms, and further applications to both organic synthesis and
industrial processes. Applications and interest in organotransition metal chemistry
have increased manifold due to not only its novelty, but also the unusual advantage, for example, nearly immediate application to chemical and pharmaceutical
industries. Many applications of organotransition compounds utilize this robustness,
which is even further elevated in cyclometalated compounds or units. In turn, the
ease of use of the metalation reaction in activating H-C or X-C functions opens a
vast field of synthetic organometallic chemistry.
Lead Guest Editor
Rajeev Singh, University of Delhi, New
Delhi, India
[email protected]
Although most new drugs are carbon based compounds, there is an increasing
realization that many metal ions are involved in natural biological processes
and that there is much scope for the design of metal-based therapeutic agents.
Metal complexes with their wide spectrum of coordination numbers, coordination
geometries, thermodynamic and kinetic preferences for ligand atoms, and in some
cases redox activity offer novel mechanism of action which are unavailable to organic
compounds. In general, the nature of the metal ion, its oxidation state, and the types
and number of bound ligands all exert a critical influence on the biological activity
of a metal complex. An understanding of how these factors affect biological activity
should enable the design of metal complexes with specific medicinal properties.
Sulekh Chandra, University of Delhi,
New Delhi, India
[email protected]
This special issue emphasizes the potential of organotransition metal complexes in
various fields.
Potential topics include, but are not limited to:
Synthesis and characterization of new organotransition metal complexes
including metallocene
Experimental techniques in organotransition chemistry
Role of organotransition metals against various types of cancers
Antiviral, antimicrobial, antimalarial, and antioxidant
Radioimaging
Immunosuppression
Biocatalysis and biosensors
Role as DNA intercalators
The biological properties of metal complexes, such as antimicrobial,
antioxidant, cytotoxic, or otherwise
Explaining biological properties using theoretical techniques like QSAR
Guest Editors
Luiz Gonzaga De França Lopes,
Universidade Federal do Ceará,
Fortaleza, Brazil
[email protected]
Pratibha Chaudhary, University of
Delhi, New Delhi, India
[email protected]
Amit Kumar, JAIST Housing, Ishikawa,
Japan
[email protected]
Manuscript Due
Friday, 23 January 2015
First Round of Reviews
Friday, 17 April 2015
Publication Date
Friday, 12 June 2015