Nevus Anaemicus =الوحمة فقيرة الدم
Transcription
Nevus Anaemicus =الوحمة فقيرة الدم
اﻠدﻢ ﻓﻘﻴرﺔ اﻠوﺤﻤﺔ= Nevus Anaemicus 1/3 اﻠدﻢ ﻓﻘﻴرﺔ اﻠوﺤﻤﺔ= Nevus Anaemicus 2/3 Nevus Anaemicus =اﻠدﻢ ﻓﻘﻴرﺔ اﻠوﺤﻤﺔ 1 is Nevus Anemicus was Nevus macule catecholamines first anemicus or described patch, with as by abe shown resultant congenital Vorner below. vasoconstriction. 1906. vascular The lesional anomaly pallor Nevus that is anemicus presents due to aLesions clinically localized isand an uncommon as hypersensitivity a hypopigmented disorder to and Pathophysiology Intralesional histamine However, alpha-adrenergic best catecholamines. termed erythema fails amay injection pharmacologic to induce blocking does of bradykinin, the follow agent, anticipated nevus an pilocarpine. axillary acetylcholine, resulting vasodilatation sympathetic These serotonin, increased findings or block erythema nicotine, suggest vascular or intradermal in that the 5-hydroxytryptamine, sensitivity affected nevus injection anemicus to area. of the is and studies endothelial several anemicus that pharmacologic may adhesion show best This donor molecule conclusion anomalies termed site dominance. ainduction pharmacologic is are further involved (E It also supported selectin and has nevus. further expression) been by autograft proposed supporting may exchange that be an involved, idea abnormality transplantation that suggesting nevus in The prevalence of nevus anemicus is not known, but itmacules. is not rare. Lesions of nevus anemicus usually persist unchanged throughout life. They are asymptomatic. No racial predilection has been noted in the literature for nevus anemicus. Nevus anemicus appears more frequently in females. nevus present as an incidental anemicus since birth finding typically may and be grows on present present skin with examination. at with the birth an child. or asymptomatic first Frequently, appreciated pale the lesion in macule early of childhood.Patients or nevus patch anemicus that has is been with noted Clinically, irregular multiple the asymptomatic. overlooked. upper and margins nevus chest. Nevus anemicus Nevi that be located may anemicus anemicus be is on ain surrounded circumscribed, any occur is noted part more of at by the birth frequently satellite rounded, body, or in but early in oval most females childhood, or lesions linear pale although are commonly may usually macule be itsingle are may or found patch or be easily with on frequency in patients usually with unchanged throughout life. Lesions occur with increased extensive and have been observed in close association .from Areas of nevus with anemicus frequently are capillary malformations of also characterized port-wine has been by described vascular type, a in phenomenon and patients melanocytic with attributed phakomatosis nevi. to somatic pigmentovascularis, recombination. Nevus a syndrome anemicus Phakomatosis melanoma. pigmentovascularis type IIa has been associated with primary choroidal Causes Nevus hypersensitivity anemicus to is catecholamines, due topersists aneurofibromatosis congenital leading anomaly to localized of the cutaneous vasoconstriction. vasculature resulting in Treatment Medical Care Treatment appearance makeup. generally of the nevus is not anemicus required for lesion nevus may anemicus. benefit from Patients the application troubled by of the camouflage cosmetic Medication No therapy isstain available for nevus anemicus. 3/3
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