Maturation of Erythrocytes - Fall River Public Schools
Maturation of Erythrocytes
is the formation of red blood cells, i.e., the
developmental processes of the red blood cells.
occurs in the red bone marrow from the
descendants of the proerythroblast stem cell by the
processes of proliferation and differentiation
each hemocytoblast stem cell can give rise to as
many as 211 mature cells.
also called a pronormoblast
the earliest stem cell (derived from the
hemocytoblast = pluripotent
found in the red bone marrow which is
committed to develop into a red blood
The retculocyte is characterized by a
bluish hue due to ribosomes remaining in
Red Blood Cell
Growth Factor is:
any of the various regulatory proteins and
local hormones which:
▪ target the hematopoietic stem cells in the red
▪ promote the growth, organization, and
maintenance of red bone marrow and blood cells.
also referred to as EPO.
a glycoprotein hormone which stimulates the
production of red blood cells by stem cells in the
red bone marrow.
produced mainly by the kidneys.
released in response to decreased levels of oxygen
detected in the blood in the kidney nephron.