the academic centre for dentistry amsterdam

Transcription

ANNUAL
RESEARCH
REPORT
2013
Stem cell preparation
One-step surgical procedure
S i nus f l oor el evati on
Annual Research Report 2013
© ACTA, September 2014, Gustav Mahlerlaan 3004, 1081 LA Amsterdam
Edited by
Design cover
Cover
2
: T.J.M. van Steenbergen and F.M. Meijer, ACTA
: Vormgeving en fotografie, Facilitaire Dienst, ACTA
: One step surgical procedure with stem cells,
Departments of Oral Cell Biology and Oral and Maxillofacial Surgery
Academic Centre for Dentistry Amsterdam
CONTENTS
page
INTRODUCTION
4
REPORT OF THE DIRECTOR
5
The Research Institute ACTA
Evaluation of the research program
Summary of research output and input
Societal impact
Management
PhD students
Points of attention
Conclusion
5
5
6
9
10
10
13
13
DESCRIPTION OF PROGRAMS AND RESULTS
Oral Infections and Inflammation
14
Oral Regenerative Medicine
55
Other research, including education related research
90
APPENDIX:
Impact factors of SCI journals for ACTA publications
Name Index
93
94
3
INTRODUCTION
The annual report starts with chapters containing the annual survey of the director, and overviews of the
scientific activities. As in preceding years the scientific performance is subsequently presented for each
programme. Detailed information is given of dissertations, scientific publications in refereed journals, other
scientific publications, professional publications, indicators of esteem, collaborations and societal impact.
Some issues for 2013 are specifically highlighted in this report. These include the two main research themes,
i.e. research programs, on which the research of ACTA is focussed starting 2011: “Oral Infections and
Inflammation” and “Oral Regenerative Medicine”.
An overview of the output in 2013 is presented in Table 1. We are pleased to note that the output in 2013 was
high. The number of publications in refereed scientific journals and the IF-sum have considerably increased
during the last years. In 2013 the highest number of scientific publications and the highest IF sum was
accomplished. In 2013 a total of 18 PhD theses were published and defended.
Research Institute ACTA
prof.dr. V. Everts
dr. T.J.M. van Steenbergen
director of research
co-ordinator of research
Address
ACTA
Gustav Mahlerlaan 3004
1081 LA Amsterdam
The Netherlands
tel:
e-mail:
4
+31-20-5980641
[email protected]
REPORT OF THE DIRECTOR
The Research Institute ACTA
•
mission statement
Dental research at the Academic Centre for Dentistry (ACTA) focuses on the study of health and diseases of the
tissues in and around the oral cavity. Beside infectious diseases like dental caries and periodontal
inflammatory processes, attention is paid to the development, function and regenerative capacities of the
hard tissues in general, dysfunction of the masticatory system and diseases of salivary glands and oral mucosa.
It is the general aim to improve strategies for diagnosis and prevention of diseases and functional repair of the
affected tissues in and around the oral cavity.
In our attempts to fulfil this mission special care is taken to establish:
- integration of fundamental disciplines with the clinical fields
- education and further academic training of PhD-students
- promotion and improvement of the quality of the research in ACTA with special attention to the translation
of the results into applications in clinical dentistry. To this end there is a vivid interaction with professional
dental organisations and industries.
•
positioning of the research institute
National position. ACTA comprises the combined Faculties of Dentistry of the University of Amsterdam and the
VU University Amsterdam. The ACTA Research Institute is the only institute for research of the faculty.
National collaboration is organized in the Netherlands Institute of Dental Sciences (Interuniversitair
Onderzoekoverleg Tandheelkunde, IOT).
Research themes. ACTA has two main research themes. These main themes are formed around scientifically
strong groups and address relevant clinical topics. The first theme is “Oral Infections and Inflammation”; this
theme focuses on the aetiology, prevention and therapy of caries, and periodontal and endodontal infections.
The second theme is “Oral Regenerative Medicine”. This theme focuses on the biological process of
adaptation and repair of teeth, bone and periodontium, and on biocompatibility of dental materials. Both
themes have received a substantial grant from the University of Amsterdam. The ACTA research on Oral
Regenerative Medicine is also included in the interfacultary research institute MOVE, a collaboration between
the faculty of Human Movement Sciences, the VU University Medical Center and ACTA.
Research programs. Till 2008, ACTA research was organised in 12 research programs. Following the
suggestions of the external review committee in 2008, the research was re-organised in 2009 in 6 programs.
To obtain more focus, starting 2011 the research was reorganised into two new research programs, according
to the two main themes: “Oral Infections and Inflammation” and “Oral Regenerative Medicine”. Next to these
two major programs, limited other research is performed, which is mainly education related.
•
description of output, leading scientific journals in the field
The research has a relatively broad focus and deals with questions originating from clinical dental practice.
Within the research there are considerable variations in the approaches taken, ranging from fundamental
medical-biological to applied clinical. This is reflected in the type of journals in which ACTA scientists publish. In
both programs, depending on the subject, scientific findings are presented in journals read in the dental
research community, or general medical-biological literature.
Evaluation of the research program
•
external evaluation
SEP external evaluation. In 2008 an external evaluation of dental research in the Netherlands was completed
according to the Standard Evaluation Protocol designed by the VSNU. In general, the evaluation committee
considered the quality, production, relevance and academic reputation of dental research at ACTA as very
good. Based on this report, the director of the research institute has conceived several intentions to further
strengthen the research at ACTA. For more details about this evaluation we refer to the assessment report of
the committee.
5
Semi-internal evaluation. In 2010 an evaluation of the research of ACTA was performed by a committee
consisting of two external referees and two ACTA senior scientists. This committee concluded that ACTA has
both nationally and internationally a prominent position in dental research. ACTA is strong in both clinical and
fundamental research. The committee recommended continuation of the focus on the two main research
themes.
SEP internal evaluation. In 2011 an internal evaluation of the ACTA research was performed for the years
2007-2010. It was concluded that in an international perspective ACTA has a strong position in a relative large
number of dental disciplines. Based on the recommendations outlined in that evaluation and on the internal
evaluation in 2010 several strategies were made for the future research policy of ACTA. The general strategy is
to maintain both fundamental and clinically applied research, preferably in a translational way. Due to the
vulnerability of small groups and to the reduction in budget it was decided to focus the research in two
programs as mentioned above. To maintain the present quality of the research, ACTA will focus on the best
scoring research. For more details, we refer to the self-evaluation report.
Citation analysis. In 2013, the CWTS in Leiden has performed a bibliometric analysis of the ACTA scientific
publications over the years 2001-2011. One of the goals of this study was to identify possible benchmarks.
These benchmark candidates were investigated in more detail and compared with the performance of ACTA.
The conclusions of this study are as follows:
“In this study we developed and applied a method to identify benchmark candidates for institutes with a nonmainstream research profile. These benchmarks are used to position the performance of ACTA. The outcome
of this study shows an important role of ACTA in terms of output. ACTA has published an impressive amount of
papers during the period studied (1,142 papers). Also the amount of number of citations received is very high
(4,667) as well as the number of publications in the top 10% most highly cited (P_top10). It should be noted,
however, that the latter two are size-depended: the more you publish, the more citations you will receive. If
we look at the impact (MNCS and PP_top10, citations per publication normalized by field), ACTA is among the
middle group. Still the impact is well above world average (10%).”
Summary of research output and input
Table 1. Comparison of research indicators 2001-2013
Year
Dissertations
2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013
9
12
6
12
11
11
12
13
6
18
15
13
18
Refereed publications
First author from ACTA
Other scientific publications
130
86
12
137
85
8
152
106
12
170
111
8
166
130
17
189
131
13
185
117
6
214
159
24
216
132
12
196
105
18
199
103
15
208
117
14
250
127
16
Professional publications
Publications for general public
Impact factor sum
123
75
93
91
99
114
113
98
206
220
238
273
322
344
354
435
168
8
509
164
14
434
169
9
503
132
12
493
159
9
696
Personnel WP 1
45.0 47.2 47.9 49.4 46.0 46.5 50.3 43.4 40.8 36.7 36.2 39.5 42.2
WP2
5.4
5.4
6.2
6.6
4.8
7.9
7.8
9.6
7.0
7.8 10.1 9.4
6.3
WP3
9.5
9.8 10.3 7.7
6.7
7.4
6.5
5.4 12.9 13.5 14.4 17.6 19.6
Guests
2.6
2.4
2.6
1.9
2.2
4.2
4.3
3.6
pm
pm
pm
pm
pm
Total personnel
62.6 64.8 66.9 65.6 59.8 66.1 68.7 62.1 61.6 57.9 60.7 66.5 68.1
st
wp1
=
academic personnel funded by 1 source in fte; this includes direct funding by the university
nd
wp2
=
academic personnel funded by 2 source in fte; this includes research grants obtained in national
competition from NWO, STW and KNAW
rd
wp3
=
academic personnel funded by 3 source in fte; this includes research contracts for specific projects
obtained from external organisations, such as industry, governmental ministries, European Commission and
charity organisations
6
•
long time performance
Dissertations (PhD theses). The performance of the research institute over a longer period is shown in Table 1.
These data show that the number of dissertations per year has fluctuated between 6 and 18. This reflects
variations in external collaborations, such as non-ACTA employees receiving a PhD from our universities and
tenure staff members finishing their PhD. In 2013 a high number of 18 dissertations were accomplished.
PhD performance. The percentage of PhD students that finished their thesis averages at 90 % over the last 20
years, and the mean time period between start of employment and defending the thesis is 4.6 years. This
figure is corrected for the 0.6 to 0.8 fte employment of several PhD students and for long leave of absence
(e.g. maternity and illness) of some PhD students.
Scientific publications. The main attention in the research assessment at the individual and program level is
given to publications in scientific journals with a peer review referee system. This category shows a slightly
increasing number over the last 20 years, despite a relatively stable input in fte of scientific personnel. The
average quality of the publications has significantly improved over the 20-year period, as judged by the
increase of the impact factor sum (Figure 1). In 2013 the highest number of 250 refereed publications and the
highest IF sum was obtained.
Professional publications. ACTA scientists are very active in communicating their research findings not only to
the scientific community, but also to professionals. The number of professional publications in 2013 was 159.
Figure 1. Impact factor sum of ACTA publications, scientific publications in refereed journals,
professional publications and total scientific personnel in fte.
800
700
600
500
400
300
IF sum
ref publ
total fte
prof publ
200
100
0
•
notable events in 2013
Publications in high ranking journals. Outstanding contributions for the year 2013 are publications in relatively
high ranking biomedical journals, i.e. Plos Pathogens, Annals of the Rheumatic Diseases, Proceedings of the
National Academy Sciences of the United States of America, Molecular Biology and Evolution, all journals with
an impact factor higher than 8, Nature Genetics with en impact facor of 35 and the New England Journal of
Medicine with an impact factor of more than 51.
Impact factors. In addition to the output indicators given, the percentage of papers in high impact journals in
the field gives valuable information. ACTA published in total 250 scientific papers in refereed journals, of which
231 in journals with an impact factor (SCI journals). 47% of these 231 papers appeared in journals belonging to
7
the field “Dentistry, Oral Surgery and Medicine”. 23% of all publications were in the top 10% of the journals,
46% in the top 25% and 71% in the top 50% (Table 2). This means that, as in previous years, a relatively large
number of publications were published in the top journals in the field, both in dental and in non-dental
journals.
Indicators of esteem. On a personal level a number of ACTA employees rank in the top of the dental
community, as determined by the various indicators of esteem, such as editorships, invited lectures, and
congresses organised. In 2013 a total of 14 awards were received by ACTA scientists for their achievements.
For more details we refer to the description of the two research programs.
Grants. As in previous years ACTA scientists obtained several importants grants. An example of a successful
grant is the participation of ACTA in the nationally funded and oriented Top Institute Food and Nutrition (TIFN)
in 2011, where a new theme “Oral Health” has been initiated. In this theme, world players in the oral care
industry, the chewing gum industry, flavour industry, food industry and (oral) care appliances industry
collaborate with ACTA and with the Netherlands Organisation for Applied Scientific Research (TNO). Another
example is the large EU-MUNDUS project: MOVE-AGE, in which ACTA participates. At this moment two ACTA
PhD students are funded by this EU-project. Recently a large Marie Curie ITN EU project wa granted by the EU.
This project, named Euroclast, is coordinated by ACTA and involves participation of seven academies and two
industrial partners and a total of 11 PhD students.
Table 2. Percentage of publications in different quartiles
of dentistry and non-dental journals in 2013
dentistry journals
non-dental journals
all journals
numbers
percentage
numbers
percentage
numbers
percentage
top 10%
25
23 %
29
24 %
54
23 %
Quartile 1
53
49 %
54
44 %
107
46 %
Quartile 2
15
14 %
42
34 %
57
25 %
Quartile 3
30
28 %
20
16 %
50
22%
Quartile 4
10
9%
7
6%
17
7%
total
108
100%
123
100%
231
100%
•
assessment at the program level
When the research at the program level is considered, both programs perform in general equally well in terms
of parameters like input and output (personnel, PhD students, publications, dissertations etc); see Table 3.
Other research (OWI), not related to the two programs, is limited both in terms of input (personnel and
budget), and of output. Considering the very limited financial input by ACTA, and the substantial grant for
research and development for the dental simulator, the research, in particular the education related research,
is considered valuable.
8
Table 3. Summary of the number of publications, impact factor sum and academic personnel in fte
Program
OII
Dis
10
Ref publ
139 (67)
OSP
10
PP
95
PGP
8
IF
382
wp1
20,10
wp2
4,10
wp3
8,05
wp tot
34,90
ORM
10
121 (58)
6
40
1
343
22,15
2,15
8,35
32,65
OWI
-
13 (2)
1
11
-
14
-
-
0,55
0,55
ACTA*
18
250 (127)
14
160
9
696
6,25
9,40
19,60
68,10
This table summarises the number of scientific publications in refereed journals, the number of other scientific
publications, and the number of professional publications. Also the personnel involved in full time equivalent (fte) and the
impact factor-sum (IF-sum) are included in this table. The IF-sum was calculated for each program by adding together the
impact factor values of all 2013 publications.
Dis
=
number of dissertations
Ref publ =
number of scientific papers in refereed journals. Between parentheses is the number of first authors
belonging to the program in question
OSP
=
other scientific publications (international, refereed)
PP
=
professional publications
PGP
=
publications for the general public
IF
=
sum of impact factors as indexed by ISI.
wp1
=
academic personnel funded by 1st source in fte
wp2
=
academic personnel funded by 2nd source in fte
wp3
=
academic personnel funded by 3rd source in fte
wp tot =
all academic personnel in fte
OII
=
ORM
=
OWI
=
Education Institute and other research
* ACTA =
the total number of dissertations and papers reflects the total for ACTA; a dissertation or paper was
counted only once; the total impact factor sum is not a summation of the data from each program
Table 4: fte of staff and PhD students (see table 2) by type of position
Program
Staff
st
nd
PhD students
rd
st
nd
Total
rd
OII
1
13,45
2
0,70
3
4,80
1
6,65
2
3,45
3
5,90
34,90
ORM
14,70
0,65
3,10
7,45
1,50
5,25
32,65
OWI
-
-
0,20
-
-
0,35
0,55
14,10
4,90
11,50
68,10
Total
OII
ORM
OWI
=
=
=
28,15
1,35
8,10
Education Institute and other Research
Societal impact
•
impact on teaching and dental care
The prime societal values of a strong research program in a dental discipline are the effect on teaching and on
dental care. The research improves the quality of teaching given at ACTA, both for undergraduate students,
graduate students, students participating in the post-initial specialist courses, and for PhD students. New
findings and concepts are included in the curriculum at ACTA, but are also presented to dental practitioners at
frequently held education activities, e.g. Quality Practice. The Research Institute participates in the ACTA
curriculum by offering scientific training to all ACTA dental students. The societal impact of the research of
ACTA is also focussed on the influence on patient care, both within ACTA and externally. Research on different
9
main areas of interest contributes to improved prevention, diagnosis and treatment of relevant patient
groups. The high number of professional publications contributes to this societal impact.
In this annual report the societal impact of each research program is described in more detail in the respective
chapters.
•
functions in the scientific and professional community
ACTA employees take an active role as executives in international scientific organisations (87 international
functions), as members of editorial boards of scientific journals (79) and in being leading in 'wetenschappelijke
verenigingen' of researchers and dental practitioners in the Netherlands. Prof.dr. J.M. ten Cate is appointed as
an academy professor at the Royal Academy of Arts and Sciences (KNAW).
Furthermore, the societal impact is evident from the organisation of symposia and conferences in the
Netherlands and abroad, presentations for dentists, medical specialists and patient groups, memberships of
advisory councils, and frequent contacts with the industry. In addition many scientists are also practising as
dentists in specialized clinics at ACTA or in the Amsterdam region. Obviously the societal impact of their
activities, individually as clinically active professionals and leading among their peers, should be acknowledged.
The societal impact is also evident from the relatively large number of 159 professional publications. Some
ACTA researchers also wrote popularising publications aimed at a more general audience. Several research
findings were high lightened in the general press.
•
invited lectures and congresses organized
In 2013 ACTA researchers have again contributed actively in internationally held meetings, workshops and
symposiums, both as organisers and participants. A total of 136 lectures were given as ‘invited speaker’ at
international congresses and symposia. In addition a large number of presentations were given at international
congresses after selection on submission of abstracts and during congresses and symposia for a Dutch or
international audience. Due to this large number, congress abstracts are not listed in this annual report. A total
of 21 international meetings were organised by ACTA scientists.
Management
•
finances
The overall budget of the research institute is divided into a part controlled directly by the directorate and
another part that is allocated to the departments.
The institute budget (senso stricto) of k€ 911 is used for the management of the institute, salaries of PhD
students, for travel allowances of PhD students, for the organization of courses for PhD students and for
printing PhD theses.
The research budgets for the departments (in total being k€ 3472) are distributed based on a model containing
several parameters, such as external peer review, bibliometric data over the last 5 years, education, PhD
theses and external funding. In addition, standard bench fees are issued for PhD students appointed by the
research institute.
st
In addition to the university budget (1 source) ACTA scientists were involved in many research projects with
nd
external funding. The total amount of research grants (2 source) was k€ 440, and the total amount of
rd
research contracts (3 source) was k€ 2548.
•
personnel
The directorate of the institute comprises:
prof.dr. V. Everts, director of research
dr. T.J.M. van Steenbergen, co-ordinator of research
mrs. F.M. Meijer, secretary
mrs. M.H.G. Piek-Backer, secretary
0.4 fte
0.6 fte
0.6 fte
0.3 fte
The activities of the research institute directorate consist of organising scientific meetings with presentations
of PhD students, the screening of new research projects, the day-to-day interaction with graduate students on
practical matters regarding their position, compiling the annual research report, the planning of graduate
courses, allocating budgets for research to the departments, controlling the institutes budget and dealing with
general correspondence on research issues with UvA, VU etc.
10
PhD students
The ACTA PhD training program is organised in the ACTA Graduate School of Dentistry (AGSD). As ACTA has no
research master training, the AGSD is at the moment limited to the PhD program.
•
PhD student appointments
All vacancies for PhD positions have been occupied in 2013. In Figure 2 the number of new PhD students at
ACTA is shown in the years 1990 to 2013. Over the years, about 23 % of all PhD students had a foreign
nationality, about half of them from Europe, the rest from other continents. A mean number of about 9 new
PhD students were appointed per year. Due to budget restrictions only 4 new PhD students could be
appointed in 2013. About 40 % of the PhD students have a dental background (see Table 5). Of all PhD
students about 50 % is female.
The research institute has started a procedure for allocation new PhD positions for the two main research
themes. In 2013 6 new PhD students were appointed on grants awarded to the research themes. Both the
open competition and the grants for talented students or post-docs will be continued in the coming years,
however due to budget reductions, the number wil be limited.
numbers of PhD students
Figure 2. Numbers of new ACTA PhD students from the Netherlands and other countries
16
14
12
10
Foreign
8
Dutch
6
4
2
0
year of entry
Table 5: PhD students by type of undergraduate training
program
dentistry
Dutch
dentistry
other
biology /
chemistry
psychology
medicine
other
total
OII
18
14
17
4
15
7
75
ORM
9
10
10
-
19
14
63
OWI
2
-
-
-
-
1
3
Total
29
24
27
4
34
21
140
OII
ORM
OWI
=
=
=
Education Institute and other research
11
•
PhD Courses
The following courses are organised for PhD students: “Dentistry for non-dentist PhD students”, “Writing and
Presenting in English”, “Methodology and Statistics”, “Oral Biology” and “Grant Writing”. Dentistry is a
multidisciplinary science and the background of the PhD students of ACTA is diverse. Therefore, most PhD
students follow external courses on specific research areas, organized by research schools in other disciplines.
•
PhD thesis duration and completion rate
Attention has been paid to the problems related to the social security benefits of PhD students and the time
that PhD students need to finish their thesis. The mean time between start of the PhD project and the defence
of the thesis within ACTA amounts 4.6 years. This is lower than the mean duration of PhD theses in research
schools in the Netherlands being 5.1 years (see the report “Rendement en duur van promoties in de
Nederlandse onderzoekscholen”, Oost en Sonneveld, 2004).
Figure 3. Mean duration of completing the thesis of ACTA PhD students
related to the year of entry
6
5,5
years
5
4,5
4
3,5
3
year of entry
Over the last 20 years, about 90 % of all PhD students in ACTA completed their thesis (Figure 4). This high
percentage is substantially larger than the mean percentage of 75 % of PhD students who finish their thesis in
Dutch research schools according to the report by Oost en Sonneveld mentioned above.
The external review committee noted in 2008 that they were impressed by the organisation and practice of
PhD training and supervision at ACTA. They concluded that it is a well organised programme, with a
remarkably high dissertation rate.
12
Figure 4. Percentage of ACTA PhD students finishing their thesis
related to the year of entry
120
100
percenatge
80
60
40
20
0
year of entry
Points of attention
•
HRM and retirement
The research staff at ACTA has been comparatively young in the last decades. This was the result of the
merging of the dental schools in the mid 1980’s. Now we are in a situation where heads of departments and
senior scientists are retiring. Due to budget restrictions the number of persons involved in research on
st
university budget (1 source) had to be reduced slightly. Fortunately, the fte scientific personnel on grants (in
rd
particular 3 source) increased in 2013. Both research priority areas received a substantial grant from the UvA,
st
resulting in an increased 1 fte in 2012 and 2013.
•
new building in 2010
In 2010 ACTA moved to a new building located at the VU campus; this brought together groups that were
spread out over the city at four different locations. Optimal research facilities at the new ACTA building are
available to encourage collaboration between the research groups that require laboratory facilities. The
increased number of scientists at one location facilitates to jointly take initiatives, such as in molecular aspects
of dental research.
•
future developments
Within the Netherlands, graduate schools are formed at a local level to integrate research training of both
Master and PhD students. In 2007 the responsibility for PhD training at ACTA was transferred from the IOT to
the ACTA Research Institute. In 2010 the new ACTA Graduate School of Dentistry (AGSD) was formally
installed.
The research at ACTA has always been characterized by a wide range of different topics that covered most
dental disciplines. The present policy is to focus on the two specific research areas with an excellent
performance. Collaboration will be increased in the interfacultary research institute MOVE, a collaboration
between ACTA, the VU University Medical Center and the faculty of Movement Sciences at the VU University
st
Amsterdam. In coming years the research budget from the 1 source (University budget) might be seriously
nd
rd
diminished due to budget restrictions. It will be a big challenge to compete for 2 and 3 source grants and to
maintain or improve the high output that ACTA has produced in the past.
Conclusion
The analysis of the various parameters of performance shows that the research at ACTA is, despite of budget
restrictions, increasingly improving. Future performance will be dependent among others from the success in
nd
rd
obtaining 2 and 3 source grants.
13
Program Leader
Prof.dr. B.G. Loos
ACTA, Gustav Mahlerlaan 3004
1081 LA Amsterdam
Tel: +31-20-5980558
E-mail: [email protected]
Full professors
E. Bloemena
J.M. ten Cate
W. Crielaard
A. de Jongh
J. de Lange
C. van Loveren
F.R. Rozema
E.A.J.M. Schulten
L.E. Smeele
E.C.I. Veerman
G.H.W. Verrips
I. van der Waal
G.A. van der Weijden
Introduction
The oral cavity is one of the most infected parts of man. We hardly understand why most people are
completely healthy with at least a thousand different species of microorganisms in billions of numbers present
in the mouth, while other individuals develop oral infectious diseases, chronic inflammatory processes and
other pathologies, including oral cancers. The central research theme “Oral Infections and Inflammation” (OII)
focusses on the pathophysiology, epidemiology and (psycho)social aspects of oral infections and inflammation
and prevention and treatment of those, as well as defining and understanding the health of the mouth as a
complex ecosystem, with applications far beyond the mouth alone. The four topics in this program interact
with each other and can be depicted in the schematic diagram below.
14
Research objectives
1) The healthy oral cavity and good systemic health.
Oral health is an essential part of the general health of each person during his or her life. Poor oral health, oral
infections and inflammation, oral cancer and other oral pathology, can lead to major health risks and might
affect the progression of cardiovascular diseases, diabetes, cancer and cancer dissemination, systemic chronic
and acute infections and vital organ failure. Poor oral health leads to a lower quality of life and economic
hardship. In collaboration with several Industrial partners, the Netherlands Organization for Applied Scientific
Research (TNO) and the Top Institute of Food and Nutrition (TIFN), we work on defining “normal” oral health
using a molecular biology approach (-omics). At the same time, we investigate the systemic effects of oral
infectious processes in relation to atherosclerotic cardiovascular disease and diabetes, both by literature
review and with an intervention trial (focus is mainly on changes in the microbiome and in biomarkers of the
named systemic diseases).
2) Innate immunity (cells/saliva), and susceptibility for caries and periodontal diseases.
Studies into the role of saliva and innate immune cells (salivary PMN) in the maintenance of oral health have a
prominent place. Several salivary proteins have strong antimicrobial capabilities and have important
proteinase inhibitory actions. Synthetic peptide analogues of salivary histatins are tested as broad spectrum
antibiotics. The influence of saliva on the interaction of oral microorganisms with oral epithelial cells and the in
vitro wound healing capacities of salivary components are also being investigated. We find PMN in rinsing
samples and they have antimicrobial functionality and are thought to have an essential role in maintaining
oral health. For periodontal diseases, we collaborate in a self-supported European consortium to identify
genetic variations, and we model periodontal disease as a complex system (environmental, life style factors,
systemic factors, randomness).
3) Epidemiology and pathophysiology of oral cancer.
Forms of oral cancer, precursor lesions of oral cancer, particularly leukoplakia, and salivary tumours are
studied. Amongst others, the prognostic value of molecular markers is examined with regard to the malignant
transformation of leukoplakia, and the role of the human papilloma virus (HPV) has been studies. Poor oral
health with its concomitant increase in the oral bacterial load, can predispose for oral cancer. Oral infections
are independently associated with oral (pre)cancers. Therefore, not only the traditional risk factors smoking
and alcohol usage play a role in oral cancer, but also oral bacteria, yeast and virus. Laboratory and clinical
studies are ongoing. Intervention in the precursor lesions of oral cancer, particularly leukoplakia, may prevent
the development of frank malignancies. Also other odontogenic tumours are studied, with emphasis on
ameloblastomas and keratocystic odontogenic tumours. Characterization is also included of salivary gland
tumours at the genomic and protein level.
4) Prevention and therapy of oral infections and inflammation.
The knowledge that oral infections may have systemic effects, provides a fundamental basis for new costeffective prevention programs as well as economic and social spin-off product-innovations in the food and oral
care products and dental restorative materials. The dental and medical profession is (re)educated with new
knowledge on the fundamentals of normal oral health and the risks of having chronic oral inflammatory
15
processes. The formation, structure and properties of oral and dental biofilms are studied, also in relation to
tooth and implant structures. In addition, new antimicrobials and peptides have come into focus as caries and
periodontitis preventive agents. Studies into the most effective clinical measures to prevent inflammation of
the gingiva and mucosa and to control oral health are being conducted, including substantial efforts to reach
clinical standards for evidence based dentistry. Part of successful prevention measures is to improve and to
maintain the well-being of both regular dental patients and subgroups of patients suffering from (extreme
forms of) anxiety or (anticipated) pain or from physical/mental handicaps.
The researchers within the theme “Oral Infections and Inflammation” have an international prominence in the
field of oral health and have acquired a global leadership role in the emerging field of complex ecosystems
such as the oral cavity; thus understanding of oral infections, inflammatory processes, oral cancer and the
definition of a normal, healthy oral cavity including psychosocial factors. We have been awarded a grant from
the University of Amsterdam (UvA) (starting date 1-1-2011) and we demonstrated the multiplier effect (both
on the academic as well as the economic aspects) by participating in the Top Institute of Food and Nutrition
(TIFN) (contract signed December 2011, first year research in 2012).
Results obtained in 2013
Preclinical studies
•
•
•
•
•
•
16
The generation of “better” antimicrobial peptides originating from natural salivary peptides is ongoing.
Structural modifications varying from specific substitutions to cyclization of these peptides have increased
the insight in the mode of action of these novel bactericidal and fungicidal agents. These are important
and novel alternatives for conventional antibiotics. Antimicrobial properties of small peptides, derived
from bacterial EDFs (Extracellular Death Factors) have been explored. It was found that these peptides
reduced via a stereospecific mechanism the size of Bacillus globigii. In addition we discovered possibilities
for new protective coatings on mucosal surfaces; the feasibility of “sphingoid” based components for the
protection of oral surfaces against chemical and bacterial injury will be further explored.
A novel versatile enzyme-based method was developed for in situ functionalization of biomaterial
surfaces. In a proof of principle study polystyrene surface was primed with an anchoring peptide derived
from salivary agglutinin and equipped with a suitable acceptor motif. This was subsequently enzymatically
coupled to a bacterial repellent polyethylene (PEG)-tail. This resulted in a significant decrease of bacterial
adherence to the surface.
Characterization of bacterial surface structure is essential for fundamental research as well as for clinical
purposes, such as vaccine development. With new technology we developed and established a novel and
rapid method by which the presence of virulence factors on the cell walls of bacteria comprehensively can
be analysed; this was validated on S. aureus. In fact, this method revealed all kinds of antigens for possible
vaccine development.
Within this –omics era, we identified in saliva with proteomics numerous (un)known molecules. Novel
mathematic models are developed to comprehensively analyse the huge amount of data emerging from
salivary biomarkers.
Model systems for several oral infections were developed and exploited. The influence of oral bacteria on
epithelial cell migration in vitro was established. Cytokine and matrix metalloproteinase expression in
fibroblasts from peri-implantitis lesions in response to viable P. gingivalis were studied, as well as the
influence of titanium on in vitro fibroblast-P. gingivalis interaction in peri-implantitis. It became clear that
gingival fibroblast responsiveness is differentially affected by P. gingivalis. Further, oral implant surface
roughness has a clear effect on bacterial biofilm formation (and therefore treatment efficacy). In another
work, we showed that the effect of metalloporphyrins on red autofluorescence from oral bacteria; we
concluded that the bacteria related to dental caries and periodontal disease exhibit red autofluorescence,
but this extent is dependent on the nutrients present, such as metalloporphyrins, suggesting that the
metabolic products of the oral biofilm could be responsible for red autofluorescence.
Furthermore we explored photodynamic antimicrobial chemotherapy using five different Enterococcus
faecalis strains in vitro in a rootcanal. In a new in vitro biofilm model we studied the possibilities for
endodontic disinfection; a modified salt solution was tested for cytotoxicity, interaction with dentine and
killing efficacy on multispecies biofilms: the incubation of modified vanadium chloroperoxidase in the
presence of its substrates with in vitro E. faecalis biofilms showed a significant antimicrobial effect at the
root canal pH. The cytotoxicity tests showed biocompatibility.
Clinical studies
•
•
•
•
•
•
•
Currently research on protease based profiling crosses the borders of bacterial diagnosis expanding
towards research on oral health, veterinary health (e.g. mastitis), bacterial biofilms, and even botanic
research. In the search for potential biomarkers as diagnostic tools for salivary gland tumors chromosomal
alterations will be investigated by array Comparative Genome Hybridization (arrayCGH). Also we are
working on the generation and characterization of artificial sortase substrates to target bacterial sortase
enzymes for therapeutic and diagnostic purposes.
An important line of clinical research has been expanded. Oral infections and inflammation, in particular
mucositis, has been identified as a major a side effect of hematopoietic stem cell transplant (HSCT). The
oral mucositis severely comprises quality of life and recovery of such patients, and may induce fevers or
even sepsis. We study oral systemic links, for example periodontal status and bacteremia, and we develop
clinical protocols for oral supportive care. We investigated the relationship between oral ulcerations and
bacterial species, Candida, and viruses, which revealed that mainly P. gingivalis, and P. micra, T. denticola,
F. nucleatum, C. glabrata, C. kefyr, and HSV-1 and EBV may play a role in ulcerative oral mucositis.
Furthermore HSV-1 is a predictor of ulcerations of oral mucosa following HSCT
The oral (microbial) ecology of the healthy oral cavity as well as several oral diseases was studied by
combining expert clinical evaluations and next-generation-sequencing microbial profiling techniques. The
microbiome in smokers and non-smokers with periodontitis was evaluated; patients that smoke have an
even more severely disturbed microbiome than non-smokier patients; all compared to a normal helathy
oral microbiome, which is diverse. The –omics approach has demanded machine learning and
bioinformatics, and needs unraveling the outcome of 16S rDNA-based taxonomy analysis through mock
data and simulations; thus we systematically evaluated potential bias in microbial community profiles
induced by whole genome amplification.
Systemic effects of periodontitis are being investigated with several researchers in an integrated effort.
Periodontitis is epidemiologically associated with atherosclerotic forms of cardiovascular diseases (CVD)
and diabetes mellitus. We explored the literature and test some aspects clinically which possible biological
pathways exist to explain this relationship; and in clinical interventions studies what the effects are of
periodontal intervention studies on CVD biomarkers.
Forms of oral cancer, precursor lesions of oral cancer, particularly leukoplakia, and salivary tumours are
studied. Amongst others, the prognostic value of molecular markers is examined with regard to the
malignant transformation of leukoplakia. A large survey on the presence of human papilloma virus (HPV)
has been performed. Also a study on peri-implantitis, implant loss and osteoradionecrosis after irradiation
in oral cancer patients focuses on the (long) term complications after oral cancer treatment. The
molecular genetic changes in various types of salivary gland tumours are investigated, as well as the
possibility to use saliva as a tool in diagnosing salivary gland neoplasms. In fact, studies on the presence of
miRNA profiles in saliva have demonstrated that differences in miRNAs can be found between patients
with benign and malignant parotid neoplasms. The concept of the sentinel biopsy in staging oral cancer
has also been demonstrated and validated in a large multicentre trial. To firmly establish the diagnosis of
oral leukoplakia the histopathological examination of (part of) the lesion should be included. It was shown
that DNA ploidy can be of prognostic value in the progression of oral leukoplakia. Treatment of
leukoplakias is been investigated. Based on a large cohort study it was demonstrated that leukoplakias
after treatment, either by surgery or laser evaporation, often recurs and that the risk of future malignant
transformation is not significantly reduced in these patients.
The genetic aberrations in adenoid cystic carcinoma (ACC) of the salivary glands have been investigated,
and deregulated pathways have been identified, opening future perspectives to personalized therapies.
Moreover, a review of all patients with ACC treated in our institute has been performed.
Odontogenic infections are still a point of discussion. We investigated the relationship between the spread
of head and neck infections, in relation to the causal tooth. When describing the location of infection,
most studies do not discriminate between maxillary and mandibular origin. Although the literature seems
to be unambiguous about the predetermined spread of infection, we demonstrated that it is more difficult
to predict the spread of a tooth infection than previously expected. Robust endodontic treatments will
prevent odontogenic infections: this aspect is being researched including evaluation of endodontic
treatments. Thus, (i) root canal fillings that are intended to prevent reinfection of the root canals were
tested for their ability to prevent leakage; (ii) a novel approach for root canal disinfection was tested
against biofilm as compared to chlorhexidine and sodium hypochlorite and was shown to have
comparable antimicrobial properties; (iii) inter-appointment intracanal dressing with vanadium
17
•
•
•
chloroperoxidase on in vitro E. faecalis biofilms was shown to be effective in the root canals; (iv) two
clinical studies were performed on patients with a periapical inflammatory process to demonstrate the
healing of bone lesions in 3D. The results demonstrate that 3D imaging shows a more reliable way to look
at healing of periapical lesions after root canal treatments compared to traditional radiography.
We evaluated fluoride toothpaste containing 1.5% arginine and insoluble calcium, as a new standard of
care in caries prevention; despite progess, no conclusive guidelines are yet availabel. Other anti-caries
strategies are adhesive microbeads for the targeting delivery of anticaries agents of vegetable origin.
Organic acids in Cichorium intybus inhibit virulence-related properties of oral pathogenic bacteria and new
antibacterial quaternary ammonium monomers for incorporation into CaP nanocomposite, for caries
prevention, were synthesized.
An important aspect to the translation of scientific findings to the clinic is the development of evidenced
based guidelines. For example, based on a systematic review we deduced that there is not enough
evidence to conclude that neither single, nor double antiplatelet therapy needs to be interrupted prior to
most invasive dental procedures. Recommendations were formulated for an evidence-based guideline for
dentists when performing invasive dental treatment in patients on oral antithrombotic medication. Also
continuous work has been done on comprehensively summarizing the available literature with respect to
various outcomes related to the prevention and therapy of gingivitis, periodontal and peri-implant
diseases. For example, the use of amoxicillin and metronidazole adjunctive to supra- and subgingival
debridement was summarized in a literature review: the antimicrobial therapy can enhance the clinical
benefits of non-surgical periodontal therapy in adults who are otherwise healthy.
In terms of therapy of the sequellae of caries, work has been performed on various dental materials and
the Atraumatic Restorative Treatment (ART) technique. Several clinical trials evaluated the survival rate of
approximal-ART restorations made with various glass-ionomer cements (GIC) using layered techniques.
Layered techniques increase survival, but there was no difference in survival rate among the various GIC
brands.
Academic personnel in 2013 and 2014
Research staff ACTA – OII (Oral Infections and Inflammation)
(in full time equivalents)
Position
Name
Bloemena, prof.dr. E.
Bruers, prof.dr. J.J.M.
Cate, prof.dr. J.M. ten
Crielaard, prof.dr. W.
Eijkman, prof. dr. M.A.J.
Heijden, prof.dr.G. J.M.G. van der
Jongh, prof.dr. A. de
Lange prof.dr. J. de
Loos, prof.dr. B.G.
Full professors
Loveren, prof.dr. C. van
Rozema, prof.dr. F.R.
Schulten, prof.dr. E.A.J.M.
Smeele, prof.dr. L.E.
Veerman, prof.dr. E.C.I.
Velden, prof.dr. U. van der
Verrips, prof.dr. G.H.W.
Waal, prof.dr. I. van der
Weijden, prof.dr. G.A. van der
18
fte 2013
0,20
-0,40
0,05
0,30
0,40
pm
0,35
0,40
0,10
0,40
0,10
0,10
0,20
0,10
0,10
0,60
0,10
pm
0,40
0,10
0,60
plan 2014
0,20
0,20
0,40
0,05
0,30
0,40
pm
0,50
0,40
0,10
0,40
--0,30
0,10
0,10
0,60
0,10
pm
0,40
0,05
0,60
Funding
1
3
1
3
1
3
guest
1
1
1
1
1
3
3
1
3
1
3
guest
1
1
3
Position
Senior lecturers
Other lecturers and tenured
research staff
Position
Other lecturers and tenured
research staff
Name
Wesselink, prof.dr. P.R.
Bikker, dr. F.J.
Gorter dr. R.C.
Krom, dr. B.P.
Krom, dr. B.P.
Steenbergen, dr. T.J.M. van
Strijp, dr. A.J.P. van
Wijk, dr. A.J. van
Zaura, dr. E.
Zaura, dr. E.
Aartman, dr. I.H.A.
Allard, mr.dr. R.H.B.
Alvarez Rodriquez, dds. E.
Bolscher, dr. J.G.M.
Bonifacio, dr. C.C.
Brand, dr. H.S.
Brand, dr. H.S.
Name
Brandt, dr. B.W.
Brandt, dr. B.W.
Dekker, dr. J. den
Deng, dr. D.M.
Diermen, dr. D.E. van
Duyx, drs. M.P.M.A.
Forouzanfar, dr. T.
Karagozoglu, drs. K.H.
Laine, dr. M.L.
Laine, dr. M.L.
Lagerweij, dr. M.D.
Ligtenberg, dr. A.J.M.
Lindeboom, dr. J.A.H.
Nicu, dr. E.A.
Özok, dr. A.R.
Poorterman, dr. J.H.G.
Reijden, dr. W.A. van der
Shemesh, dr. H.
Soet, dr. J.J. de
Soet, dr. J.J. de
Veen, dr.ir. M.H. van der
Wu, dr. M.K.
Total tenured staff
Non tenured staff
Al Hothali, dds. M.M.
Anssari Moin, D.
Bots, dr. C.P.
Boutsioukis, dr. C.
Gambon, dr. D.L.
Milstein, dr. D.M.J.
Özen, dr. B.
Raber-Durlacher, dr. J.E.
fte 2013
pm
0,70
0,20
0,70
0,10
0,05
0,10
0,10
0,40
0,40
0,40
0,50
0,10
0,25
0,70
0,40
0,35
0,05
fte 2013
0,50
0,30
0,05
0,80
0,10
-0,05
0,10
0,25
0,05
0,05
0,55
0,05
0,75
0,40
0,20
0,05
0,30
0,10
0,10
0,60
pm
15,85
pm
0,15
pm
0,20
pm
0,20
-0,20
pm
plan 2014
pm
0,70
0,20
0,70
0,10
0,05
0,10
0,10
0,40
0,40
0,40
0,50
0,10
pm
0,70
0,40
0,35
0,05
plan 2014
0,20
0,60
0,05
0,80
0,10
-0,05
0,10
0,30
0,05
0,05
0,55
0,05
0,70
0,40
--0,30
0,25
0,10
0,60
-15,70
pm
-pm
0,20
pm
-0,20
0,40
pm
funding
1
1
1
1
3
1
1
2
1
1
3
1
1
3
1
1
1
3
funding
1
3
1
1
1
1
1
1
1
3
3
1
1
1
1
3
1
1
1
3
2
guest
guest
3
guest
1
guest
1
3
1
guest
19
Position
Non tenured staff
PhD students
20
Name
Scheres, dr. C.R.
Sluis, dr. L.W.M. van der
Arikan, MSc. M.
Benzian, dds. H.
Bizzarro, dds.MSc. S.
Boink, MSc. M.A.
Bont, P. de
Broers, drs. D.L.M.
Brouns, drs. E.R.E.A.
Cukkemane, MSc. N.
Dautovic, E.
Dekker, drs. H.
Dekker, drs. H.
Dijk, MSc. I.A., van
Dijk, drs. S., van
Donders, drs. H.C.M.
Duijster, drs. D.
Duijster, drs. D.
Fernandez y Mostajo, MSc. M.
Geurs, N.C.
Groot, M. de
Gunput, MSc. S.T.G.
Hansenova Manaskova, MSc. S.
Haverman, MSc. T.M.
Helmers, drs. R.
Hertog, drs. D.
Houtem, drs. C.M.H.H. van
Imangaliyev MSc. S.
Janus, ir. M.M.
Jong, MSc. B.G. de
Jong-Lenters, drs. M. de
Kaiwar, A.
Kaman - van Zanten, ing. W.E.
Koopman, drs. J.E.
Koopman, drs. J.E
Krikken, drs. J.B.
Laheij, drs. A.M.G.A.
Liang, dds. Y.H.
Louropoulou, dds. A.
Macedo, dds. R.G. de
May, MSc. A.
May, MSc. A.
Metska, dds. M.E.
Mevissen-Renckens, E.H.M.
Moghimi, drs. M.
Moinzadeh, dds. A.T.M.
Neelakantan, dds. P.
Papantonopoulos, dds. G.H.
Persoon, MSc. I.F.
Prodan, MSc. A.
fte 2013
1,00
pm
0,35
pm
0,45
0,75
pm
pm
pm
0,70
pm
0,20
0,25
0,75
0,10
0,10
0,30
0,45
0,45
pm
pm
0,75
0,75
0,20
0,10
pm
0,35
0,15
0,75
0,75
0,75
pm
pm
pm
0,60
0,15
0,05
0,45
pm
0,30
0,40
0,35
0,40
pm
pm
0,10
pm
pm
pm
0,45
0,75
plan 2014
1,00
pm
-pm
0,40
0,70
pm
pm
pm
-pm
0,20
0,25
0,75
0,10
0,10
0,30
0,45
0,45
pm
pm
0,75
0,75
0,20
0,20
pm
0,35
0,15
0,75
0,75
0,75
pm
pm
pm
0,60
0,15
0,05
0,20
pm
0,10
-0,35
0,40
pm
pm
0,05
pm
pm
pm
0,45
0,75
funding
3
guest
3
guest
1
2
guest
guest
guest
2
guest
1
3
2
3
1
1
3
3
guest
guest
1
2
1
3
guest
1
3
3
3
1
guest
guest
guest
1
3
1
1
guest
1
1
1
3
guest
guest
1
guest
guest
guest
1
3
Position
plan 2014
0,20
-0,45
pm
pm
pm
0,50
-0,60
0,40
pm
pm
pm
pm
0,45
0,45
0,30
-16,60
plan 2014
19,25
funding
1
1
1
guest
guest
guest
3
3
3
1
guest
guest
guest
guest
2
1
3
3
total 1 funding
fte 2013
0,10
0,20
0,45
pm
pm
pm
0,75
0,10
0,60
0,40
pm
pm
pm
pm
0,45
0,45
0,30
0,10
19,05
fte 2013
20,10
total 2nd funding
4,10
3,35
2
total 3rd funding
10,70
9,70
3
Total research staff
34,90
32,30
PhD students
Total non tenured staff
st
Name
Rademacher, MSc. W.M.H.
Ramawadh, MSc. R.S.
Rijkschroeff, MSc. P.
Roos, C. de
Scheerman, MSc. J.F.M.
Schreuder, W.H.
Sijbrandij, drs. T.
Sleen, drs. J. van der
Slot, drs. D.E.
Teeuw, MSc. W.J.
Tuk, J.C.
Veerbeek, H.J.
Verstraaten, mw. S.
Vleugel, B. van der
Volgenant, drs. C.M.C.
Waal, drs. S.V. van der
Zande, MSc. M.M. van der
Zecha, drs. J.A.E.M.
funding
1
Output
Dissertations
Brouns, E.R.E.A. (2013, June 06). Oral leukoplakia a clinical, histopathological and molecular study. VU
University Amsterdam (125 pag.). Prom./coprom.: prof.dr. E. Bloemena & prof.dr. I. van der Waal.
Diermen, D.E. van (2013, April 17). Oral antithrombotics and dentistry: Current state of affairs and guideline
proposal. Universiteit van Amsterdam (195 pag.). Prom./coprom.: prof.dr. I. van der Waal & prof.dr. J.
Hoogstraten.
Irshad, M. (2013, December 19). Host-bacterial interaction in peri-implantitis. VU University Amsterdam (162
pag.). Prom./coprom.: prof.dr. W. Crielaard, prof.dr. B.G. Loos, prof.dr. D. Wismeijer & dr. M.L. Laine.
Krikken, J.B. (2013, June 14). Dental anxiety and behaviour management problems: The role of parents.
Universiteit van Amsterdam (183 pag.). Prom./coprom.: prof.dr. J.M. ten Cate, dr. J.S.J. Veerkamp & dr. A.J.
van Wijk.
Leito, J.T.D. (2013, April 18). The role of salivary agglutinin and statherin in the defense against microorganisms. VU University Amsterdam (143 pag.). Prom./coprom.: prof.dr. E.C.I. Veerman, prof.dr. A. van
Nieuw Amerongen & dr. A.J.M. Ligtenberg.
Liang, Y.H. (2013, September 27). The outcome of root-canal treatments assessed by cone-beam computed
tomography. Universiteit van Amsterdam (131 pag.). Prom./coprom.: prof.dr. P.R. Wesselink, dr. M.K. Wu
& dr. H. Shemesh.
Macedo, R.G. de (2013, December 20). Optimizing the chemical aspect of root canal irrigation. Universiteit van
Amsterdam (139 pag.). Prom./coprom.: prof.dr. P.R. Wesselink, dr. L.W.M. van der Sluis & prof.dr. A.M.
Versluis.
Rollman, A. (2013, November 27). Improvement and care seeking for temporomandibular-pain complaints:
The complexity of chronic pain. Universiteit van Amsterdam (134 pag.). Prom./coprom.: prof.dr.ir. M.
Naeije, dr. C.M. Visscher & dr. R.C. Gorter.
Strydonck, D.A.C. Van (2013, January 18). Chlorhexidine and the control of plaque and gingivitis. Universiteit
van Amsterdam (192 pag.). Prom./coprom.: prof.dr. U. van der Velden & prof.dr. G.A. van der Weijden.
21
Vermaire, J.H. (2013, May 24). Optimizing oral health: Towards a tailored, effective and cost-effective dental
care. Universiteit van Amsterdam (156 pag.). Prom./coprom.: prof.dr. C. van Loveren, W.B.F. Brouwer,
prof.dr. J. Hoogstraten & dr. J.H.G. Poorterman.
Scientific publications (refereed)
Amaechi, B.T. & Loveren, C. van (2013). Fluorides and non-fluoride remineralization systems. Monographs in
Oral Science, 23, 15-26.
Bailey, E., Worthington, H.V., Wijk, A. van, Yates, J.M., Coulthard, P. & Afzal, Z. (2013). Ibuprofen and/or
paracetamol (acetaminophen) for pain relief after surgical removal of lower wisdom teeth. Cochrane
Database of Systematic Reviews, 12, CD004624.
Berg, D.P.G. van den, Vleugel, B.M. van der, Staring, A.B.P., Bont, P.A.J. de & Jongh, A. de (2013). EMDR in
psychosis: guidelines for conceptualization and treatment. Journal of EMDR Practice and Research, 7(4),
208-224.
Besseling, S., Ngonephady, S. & Wijk, A.J. van (2013). Pilot survey on dental health in 5-12-year-old school
children in Laos. Journal of Investigative and Clinical Dentistry, 4(1), 44-48.
Bikker, F.J., Cukkemane, N., Nazmi, K. & Veerman, E.C.I. (2013). Identification of the hydroxyapatite-binding
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recursive partitioning analysis of immunologic factors. Journal of Periodontology, 84(7), 974-984.
Papantonopoulos, G., Takahashi, K., Bountis, T. & Loos, B.G. (2013). Mathematical modeling suggests that
periodontitis behaves as a non-linear chaotic dynamical process. Journal of Periodontology, 84(10), e29e39.
Papantonopoulos, G., Takahashi, K., Bountis, T. & Loos, B.G. (2013). Using cellular automata experiments to
model periodontitis: a first step towards understanding the nonlinear dynamics of the disease.
International Journal of Bifurcation and Chaos, 23(3), 1-17.
26
Papetti, A., Mascherpa, D., Carazzone, C., Stauder, M., Spratt, D.A., Wilson, M., Pratten, J., Ciric, L., Lingström,
P., Zaura, E., Weiss, E., Ofek, I., Signoretto, C., Pruzzo, C. & Gazzani, G. (2013). Identification of organic acids
in Cichorium intybus inhibiting virulence-related properties of oral pathogenic bacteria. Food Chemistry,
138(2-3), 1706-1712.
Persoon, I.F., Hoogenkamp, M.A., Bury, A., Wesselink, P.R., Hartog, A.F., Wever, R. & Crielaard, W. (2013).
Antimicrobial effect of a modified vanadium chloroperoxidase on Enterococcus faecalis biofilms at root
canal pH. Journal of Endodontics, 39(8), 1035-1038.
Puknun, A., Bolscher, J.G.M., Nazmi, K., Veerman, E.C.I., Tungpradabkul, S., Wongratanacheewin, S.,
Kanthawong, S. & Taweechaisupapong, S. (2013). A heterodimer comprised of two bovine lactoferrin
antimicrobial peptides exhibits powerful bactericidal activity against Burkholderia pseudomallei. World
Journal Of Microbiology & Biotechnology, 29(7), 1217-1224.
Putten, G.J. van der, Brand, H.S., Visschere, L.M.J., Schols, J.M.G.A. & Baat, C. de (2013). Saliva secretion rate
and acidity in a group of physically disabled older care home residents. Odontology, 101(1), 108-115.
Raber-Durlacher, J.E., Laheij, A.M.G.A., Epstein, J.B., Epstein, M., Geerligs, G.M., Wolffe, G.N., Blijlevens,
N.M.A. & Donnelly, J.P. (2013). Periodontal status and bacteremia with oral viridans streptococci and
coagulase negative staphylococci in allogeneic hematopoietic stem cell transplantation recipients: a
prospective observational study. Supportive Care in Cancer, 21(6), 1621-1627.
Raber-Durlacher, J.E., Bültzingslöwen, I. von, Logan, R.M., Bowen, J., Al-Azri, A.R., Everaus, H., Gerber, E.,
Gomez, J.G., Pettersson, B.G., Soga, Y., Spijkervet, F.K.L., Tissing, W.J.E., Epstein, J.B., Elad, S. & Lalla, R.V.
(2013). Systematic review of cytokines and growth factors for the management of oral mucositis in cancer
patients. Supportive Care in Cancer, 21(1), 343-355.
Rietbergen, M.M., Brakenhoff, R.H., Bloemena, E., Witte, B.I., Snijders, P.J.F., Heideman, D.A.M., Boon, D.,
Koljenovic, S., Baatenburg-de Jong, R.J. & Leemans, C.R. (2013). Human papillomavirus detection and
comorbidity: critical issues in selection of patients with oropharyngeal cancer for treatment De-escalation
trials. Annals of Oncology, 24(11), 2740-2745.
Rietbergen, M.M., Leemans, C.R., Bloemena, E., Heideman, D.A.M., Braakhuis, B.J.M., Hesselink, A.T., Witte,
B.I., Baatenburg de Jong, R.J., Meijer, C.J.L.M., Snijders, P.J.F. & Brakenhoff, R.H. (2013). Increasing
prevalence rates of HPV attributable oropharyngeal squamous cell carcinomas in the Netherlands as
assessed by a validated test algorithm. International Journal of Cancer, 132(7), 1565-1571.
Roelofs, D., Timmermans, M.J.T.N., Hensbergen, P., Leeuwen, H. van, Koopman, J., Faddeeva, A., Suring, W.,
Boer, T.E. de, Marien, J., Boer, R., Bovenberg, R. & Straalen, N.M. van (2013). Functional isopenicillin n
synthase in an animal genome. Molecular Biology and Evolution, 30(3), 541-548.
Rollman, A., Visscher, C.M., Gorter, R.C. & Naeije, M. (2013). Improvement in patients with a TMD-pain report.
A 6-month follow-up study. Journal of Oral Rehabilitation, 40(1), 5-14.
Rollman, A., Gorter, R.C., Visscher, C.M. & Naeije, M. (2013). Why seek treatment for temporomandibular
disorder pain complaints? A study based on semi-structured interviews. Journal of Orofacial Pain, 27(3),
227-234.
Rosema, N.A.M., Hennequin-Hoenderdos, N.L., Versteeg, P.A., Palenstein Helderman, W.H. van, Velden, U.
van der & Weijden, G.A. van der (2013). Plaque-removing efficacy of new and used manual toothbrushes a professional brushing study. International Journal of Dental Hygiene, 11(4), 237-243.
Rouxel, P., Duijster, D., Tsakos, G. & Watt, R.G. (2013). Oral health of female prisoners in HMP holloway:
Implications for oral health promotion in UK prisons. British Dental Journal, 214(12), 627-632.
Schaefer, A.S., Bochenek, G., Manke, T., Nothnagel, M., Graetz, C., Thien, A., Jockel-Schneider, Y., Harks, I.,
Staufenbiel, I., Wijmenga, C., Eberhard, J., Guzeldemir-Akcakanat, E., Cine, N., Folwaczny, M., Noack, B.,
Meyle, J., Eickholz, P., Trombelli, L., Scapoli, C., Nohutcu, R., Bruckmann, C., Doerfer, C., Jepsen, S., Loos,
B.G. & Schreiber, S. (2013). Validation of reported genetic risk factors for periodontitis in a large-scale
replication study. Journal of Clinical Periodontology, 40(6), 563-572.
Schenkein, H.A. & Loos, B.G. (2013). Inflammatory mechanisms linking periodontal diseases to cardiovascular
diseases (also published in Journal of Periodontology 2013 Apr 84 (4 Suppl): S51-69). Journal of Clinical
Periodontology, 40(Suppl. 14), S51-S69.
Scheres, N. & Crielaard, W. (2013). Gingival fibroblast responsiveness is differentially affected by
Porphyromonas gingivalis: implications for the pathogenesis of periodontitis. Molecular Oral Microbiology,
28(3), 204-218.
Schoonheim-Klein, M., Gresnigt, C. & Velden, U. van der (2013). Influence of dental education in motivational
interviewing on the efficacy of interventions for smoking cessation. European Journal of Dental Education,
17(1), e28-e33.
27
Signoretto, C., Marchi, A., Bertoncelli, A., Burlacchini, G., Milli, A., Tessarolo, F., Caola, I., Papetti, A., Pruzzo, C.,
Zaura, E., Lingström, P., Ofek, I., Spratt, D.A., Pratten, J., Wilson, M. & Canepari, P. (2013). Effects of
mushroom and chicory extracts on the shape, physiology and proteome of the cariogenic bacterium
Streptococcus mutans. BMC Complementary and Alternative Medicine, 13, 117.
Sijbrandij, T., Cukkemane, N., Nazmi, K., Veerman, E.C.I. & Bikker, F.J. (2013). Sortase A as a tool to
functionalize surfaces. Bioconjugate Chemistry, 24(5), 828-831.
Silva, T., Adão, R., Nazmi, K., Bolscher, J.G.M., Funari, S.S., Uhríková, D. & Bastos, M. (2013). Structural
diversity and mode of action on lipid membranes of three lactoferrin candidacidal peptides. Biochimica et
Biophysica Acta Biomembranes, 1828(5), 1329-1339.
Snijders, R.S., Wijk, A.J. van & Lindeboom, J.A. (2013). A comparative study of the Osstell™ versus the Osstell
Mentor™ to evaluate implant stability in human cadaver mandibles. Journal of Oral Rehabilitation, 40(10),
774-779.
Soet, J.J. de (2013). Harmonizing evidence based infection prevention in Europe. Acta Stomatologica Naissi,
29(67), 1221-1223.
Svircevic, V., Passier, M.M., Nierich, A.P., Dijk, D. van, Kalkman, C.J. & Heijden, G.J. van der (2013). Epidural
analgesia for cardiac surgery. Cochrane Database of Systematic Reviews, 6(6), CD006715.
Timmermans, A.J., Brandsma, D., Smeele, L.E., Rosingh, A.W., Brekel, M.W.M. van den & Lohuis, P.J.F.M.
(2013). Cervical osteomyelitis after carbon dioxide laser excision of recurrent carcinoma of the posterior
pharyngeal wall. The Annals of Otology Rhinology & Laryngology, 122(4), 273-276.
Tokede, O., White, J., Stark, P.C., Vaderhobli, R., Walji, M.F., Ramoni, R., Schoonheim-Klein, M., Kimmes, N.,
Tavares, A. & Kalenderian, E. (2013). Assessing use of a standardized dental diagnostic terminology in an
electronic health record. Journal of Dental Education, 77(1), 24-36.
Tokede, O., Walji, M., Ramoni, R., White, J.M., Schoonheim-Klein, M., Kimmes, N.S., Vaderhobli, R., Stark, P.C.,
Patel, V.L. & Kalenderian, E. (2013). Treatment planning in dentistry using an electronic health record:
implications for undergraduate education. European Journal of Dental Education, 17(1), e34-e43.
Turksma, A.W., Bontkes, H.J., Heuvel, H. van den, Gruijl, T.D. de, Blomberg, B.M.E. von, Braakhuis, B.J.M.,
Leemans, C.R., Bloemena, E., Meijer, C.J.L.M. & Hooijberg, E. (2013). Effector memory T-cell frequencies in
relation to tumour stage, location and HPV status in HNSCC patients. Oral Diseases, 19(6), 577-584.
Turksma, A.W., Braakhuis, B.J.M., Bloemena, E., Meijer, C.J.L.M., Leemans, C.R. & Hooijberg, E. (2013).
Immunotherapy for head and neck cancer patients: shifting the balance. Immunotherapy, 5(1), 49-61.
Tytgat, S.H.A.J., Zee, S.C. van der, Ince, C. & Milstein, D.M.J. (2013). Carbon dioxide gas pneumoperitoneum
induces minimal microcirculatory changes in neonates during laparoscopic pyloromyotomy. Surgical
Endoscopy and other interventional Techniques, 27(9), 3465-3473.
Wijk, A.J. van, Lobbezoo, F. & Hoogstraten, J. (2013). Reliability and validity of a continuous pain registration
procedure. European Journal of Pain, 17(3), 394-401.
Verrips, G.H.W. & Schuller, A.A. (2013). Subjective oral health in dutch adults. Dentistry Journal, 2(1), 12-18.
Volgenant, C.M.C., Veen, M.H. van der, Soet, J.J. de & Cate, J.M. ten (2013). Effect of metalloporphyrins on
red autofluorescence from oral bacteria. European Journal of Oral Sciences, 121(3), 156-161.
Waal, I. van der (2013). Are we able to reduce the mortality and morbidity of oral cancer; Some
considerations. Medicina Oral Patologia Oral y Cirurgia Bucal, 18(1), E33-E37.
Walji, M.F., Kalenderian, E., Tran, D., Kookal, K.K., Nguyen, V., Tokede, O., White, J.M., Vaderhobli, R., Ramoni,
R., Stark, P.C., Kimmes, N.S., Schoonheim-Klein, M.E. & Patel, V.L. (2013). Detection and characterization of
usability problems in structured data entry interfaces in dentistry. International Journal of Medical
Informatics, 82(2), 128-138.
Weert, S. van, Bloemena, E., Waal, I. van der, Bree, R. de, Rietveld, D.H.F., Kuik, D.J. & Leemans, C.R. (2013).
Adenoid cystic carcinoma of the head and neck: a single-center analysis of 105 consecutive cases over a 30year period. Oral Oncology, 49(8), 824-829.
Wegner, I., Widyahehening, I.S., Tulder, M.W. van, Blomberg, S.E.I., Vet, H.C.W. de, Brønfort, G., Bouter, L.M.
& Heijden, G.J. van der (2013). Traction for low-back pain with or without sciatica. Cochrane Database of
Systematic Reviews, 8, CD003010.
Yekta, S.S., Lampert, F., Kazemi, S., Kazemi, R., Brand, H.S., Baart, J.A. & Mazandarani, M. (2013). Evaluation of
new injection and cavity preparation model in local anesthesia teaching. Journal of Dental Education, 77(1),
51-57.
Zandbergen, D., Slot, D.E., Cobb, C.M. & Weijden, F.A. van der (2013). The clinical effect of scaling and root
planing and the concomitant administration of systemic amoxicillin and metronidazole: a systematic
review. Journal of Periodontology, 84(3), 332-351.
28
Zande, M.M. van der, Gorter, R.C. & Wismeijer, D. (2013). Dental practitioners and a digital future: an initial
exploration of barriers and incentives to adopting digital technologies. British Dental Journal, 215(11), 1-5.
Zhou, C., Weir, M.D., Zhang, K., Deng, D.M., Cheng, L. & Xu, H.H.K. (2013). Synthesis of new antibacterial
quaternary ammonium monomer for incorporation into CaP nanocomposite. Dental Materials, 29(8), 859870.
Zwier, N., Huysmans, M.C.D.N.J.M., Jager, D.H.J., Ruben, J., Bronkhorst, E.M. & Truin, G.J. (2013). Saliva
parameters and erosive wear in adolescents. Caries Research, 47(6), 548-552.
Scientific publications (non-refereed)
Amaechi, B.T., Amerongen, J.P. van, Loveren, C. van & Kidd, E.A.M. (2013). Caries management: diagnosis and
treatment strategies. In T.J. Hilton, J.L. Ferracane & J.C. Broome (Eds.), Summitt’s Fundamentals of
operative dentistry: : A contemporary approach 4th Edition (pp. 93-130). Quintessence Publishing Co Inc.
Brand, H.S., Ouzzine, R. & Bots, C.P. (2013). Sticky saliva products. British Dental Journal, 214(3), 95.
Brand, H.S. (2013). Summary of: an in vitro investigation of the erosive potential of smoothies: commentary.
British Dental Journal, 214(4), 173.
Doherty, R. & Cate, B. ten (2013). Bob ten Cate: 'Ninety percent of the cells in our body are bacterial cells'.
British Dental Journal, 215(10), 533-535.
Jongh, A. de (2013). Cosmetic Dentistry: concerns with facial appearance and body dysmorphic disorder. In D.I.
Mostofsky & F. Fortune (Eds.), Behavioral Dentistry, second edition (pp. 109-119). Wiley Blackwell.
Wijk, A.J. van, Lobbezoo, F. & Hoogstraten, J. (2013). Authors' reply to the comment by Sabour. European
Journal of Pain, 17(3), 462.
Professional Publications
Aartman, I.H.A. (2013). Hoe waarschijnlijk is mijn diagnose? Quality Practice. Nascholingstijdschrift voor
Tandartsen, 8(5), 16-19.
Abraham-Inpijn, L. & Brand, H.S. (2013). Reactie op: Europese Medisch Risico Registrerend Anamnese
systeem. Nederlands Tijdschrift voor Tandheelkunde, 120(2), 56.
Allard, R.H.B. & Baart, J.A. (2013). Juridische aspecten. Quality Practice. Nascholingstijdschrift voor
Tandartsen, 9, 42-44.
Amerongen, W.E. van (2013). Kleine gaatjes bij kleine mensjes: wat moet je ermee?! Quality Practice.
Nascholingstijdschrift voor Mondhygiënisten, 6(1), 45-51.
Amerongen, W.E. van, Martens, L.C., Stel, G. & Veerkamp, J.S.J. (2012). Kindertandheelkunde 2. Tweede,
herziene druk. Houten: Bohn Stafleu van Loghum.
Baart, J.A. & Allard, R.H.B. (2013). Pijnstillers in de tandheelkunde. Quality Practice. Nascholingstijdschrift
voor Mondhygiënisten, 5(3), 12-15.
Baart, J.A. & Brand, H.S. (2013). Is bij uitgebreide gebitsreiniging infiltratie anesthesie voldoende, of moet
daarbij ook geleidingsanesthesie worden toegepast? Mondhygiënisten Vademecum, 11(12), 1.
Baart, J.A. & Waal, I. van der (2013). Het focusvrij maken van de mond. Quality Practice. Nascholingstijdschrift
voor Tandartsen, 8(3), 33-35.
Baart, J.A. & Waal, I. van der (2013). Het focusvrij maken van de mond. Quality Practice. Nascholingstijdschrift
Baart, J.A. & Waal, I. van der (2013). Oral medicine 6. Ulceraties van de oral mucosa. Nederlands Tijdschrift
voor Tandheelkunde, 120(5), 246-249.
Baart, J.A. & Waal, I. van der (2013). Röntgendiagnostiek in de kaakchirurgie; enkele voorbeelden. Quality
Practice. Nascholingstijdschrift voor Mondhygiënisten, 6(1), 36-40.
Baas, J.D.M. & Brand, H.S. (2013). Remming van het immuunsysteem door tumoren in het hoofd-halsgebied.
Nederlands Tijdschrift voor Tandheelkunde, 120(3), 143-146.
Baat, C. de, Loveren, C. van, Maarel-Wierink, C.D. van der, Witter, D.J. & Creugers, N.H.J. (2013). Nazorg voor
duurzaamheid en profijtelijkheid van kronen en bruggen. Nederlands Tijdschrift voor Tandheelkunde,
120(7/8), 411-420.
Baiwa, A., Loos, B.G. & Bizzarro, S. (2013). Is parodontitis geassocieerd met vroeggeboorte en laag
geboortegewicht? Quality Practice. Nascholingstijdschrift voor Mondhygiënisten, 5(3), 33-40.
Bikker, F.J., Kaman, W.E. & Veerman, E.C.I. (2013). Rechtsdraaiende proteasesubstraten lijken bruikbaar voor
orale microbiologische diagnostiek. Nederlands Tijdschrift voor Tandheelkunde, 120(3), 164-167.
29
Boers, E. & Sanaan, B. (2013). Klachten tegen tandartsen. Nederlands Tandartsenblad, 68(1), 26-28.
Bots, C.P. (2013). Eiwitten en orale afweer [Bespreking van het boek The role of salivary agglutinin and
statherin in the defence-against micro-organisms]. Nederlands Tijdschrift voor Tandheelkunde, 120(11),
648.
Brand, H.S. (2013). Acute medische situaties. Quality Practice. Nascholingstijdschrift voor Mondhygiënisten,
5(3), 26-31.
Brand, H.S. (2013). Mag een patiënt met een pacemaker of ICD wel of niet behandeld worden met ultrasone
apparatuur? Mondhygiënisten Vademecum, 11(3), 1-3.
Brand, H.S. (2013). Mondzorgverleners verstrikt in richtlijnen? Nederlands Tijdschrift voor Tandheelkunde,
120(11), 595-596.
Brand, H.S. (2013). Problemen in uw praktijk. Nederlands Tijdschrift voor Tandheelkunde, 120(7-8), 363.
Brand, H.S. (2013). Risicopatiënten. In J.A. Baart & H.S. Brand (Eds.), Lokale anesthesie in de tandheelkunde
(2e druk) (pp. 183-196). Houten: Bohn Stafleu van Loghum.
Brand, H.S. & Frankhuijzen, A.L. (2013). Systemische complicaties. In J.A. Baart & H.S. Brand (Eds.), Lokale
anesthesie in de tandheelkunde (2e druk) (pp. 169-182). Houten: Bohn Stafleu van Loghum.
Brand, H.S. (2013). Schaamteproblemen [Bespreking van het boek Van gêne to schaamrood. Achtergronden
en behandeling van schaamteproblemen]. Nederlands Tijdschrift voor Tandheelkunde, 120, 285.
Brands, W.G., Ven, J.M. van der & Eijkman, M.A.J. (2013). Dossierplicht: overdracht of afschrift. Nederlands
Tijdschrift voor Tandheelkunde, 120(6), 301-305.
Brands, W.G., Ven, J.M. van der & Eijkman, M.A.J. (2013). Tandheelkunde en gezondheidsrecht 1. De
zorginhoudelijke professionele standaard. Nederlands Tijdschrift voor Tandheelkunde, 120(4), 212-215.
Brands, W.G., Ven, J.M. van der & Eijkman, M.A.J. (2013). Tandheelkunde en gezondheidsrecht 3. Informed
consent. Nederlands Tijdschrift voor Tandheelkunde, 120(6), 327-332.
Brands, W.G., Ven, J.M. van der & Eijkman, M.A.J. (2013). Tandheelkunde en gezondheidsrecht 5.
Geheimhouding en ruimtelijke privacy. Nederlands Tijdschrift voor Tandheelkunde, 120(9), 485-490.
Brands, W.G., Ven, J.M. van der & Eijkman, M.A.J. (2013). Tandheelkunde en gezondheidsrecht 6. Het effect
van zelfregulatie in de mondzorg. Nederlands Tijdschrift voor Tandheelkunde, 120(10), 547-553.
Brands, W.G., Ven, J.M. van der & Eijkman, M.A.J. (2013). Tandheelkunde en gezondheidsrecht 7. De
hulpverleningsplicht: beschikbaarheid en bereikbaarheid. Nederlands Tijdschrift voor Tandheelkunde,
120(12), 693-698.
Brands, W.G., Ven, J.M. van der & Eijkman, M.A.J. (2013). Tandheelkunde en gezondsheidsrecht 2.
Meningsverschillen over de zorginhoudelijke professionele standaard. Nederlands Tijdschrift voor
Tandheelkunde, 120.
Burgersdijk, R.C.W., Gruythuysen, R.J.M. & Loveren, C. van (2013). Richtlijn jeugd, hoe nu verder? Nederlands
Tandartsenblad, 68(7), 22-25.
Danser, M.M. & Huffels, R.A.M. (2013). Röntgendiagnostiek voor parodontale behandeling. Quality Practice.
Diermen, D. van (2013). Antitrombotische medicatie bij tandheelkundige patiënten. Quality Practice.
Diermen, D. van (2013). Multifarmacie bij ouderen en de gevolgen voor de mondgezondheid. Nederlands
Tijdschrift voor Mondhygiëne, 19(6), 28-30.
Diermen, D.E. van & Labots-Vogelesang, M. (2013). Tandartsbezoek: antistolling staken? Huisarts en
Wetenschap, 56(7), 360.
Doornik, A. van & Weijden, G.A. van der (2013). Het Eagle syndroom. De Tandartspraktijk, 34(1), 20-21.
Edeler, D. & Eijkman, M. (2012). De drinkwaterfluoridering in Nederland, 1946-1976. Een maatschappelijk
debat zonder winnaars en verliezers. Studium, 5(2), 80-94.
Eijkman, M.A.J., Dam, B.A.F.M. van, Bruers, J.J.M. & Visser, A.Ph. (2013). 50 jaar GVO en
Gezondheidsbevordering. Tandheelkundige Voorlichting: toen en nu. TSG Tijdschrift voor
Gezondheidswetenschappen, 91(3), 178-184.
Eijkman, M.A.J. (2013). De lastige patiënt. Quality Practice. Nascholingstijdschrift voor Tandartsen, 8(4), 48-50.
Eijkman, M.A.J. (2013). Gezondheidsvoorlichting en kunstmatige intelligentie. Nederlands Tijdschrift voor
Tandheelkunde, 120(12), 655.
Eijkman, M.A.J. (2013). Patiënt of klant. Nederlands Tijdschrift voor Tandheelkunde, 120, 127.
Eijkman, M.A.J. (2013). Mondzorg in sociaal perspectief [Bespreking van het boek Mondzorg in sociaal
perspectief (2e herz. druk)]. Nederlands Tijdschrift voor Tandheelkunde, 120(3), 173.
Elfrink, M. & Weerheijm, K.L. (2013). Molar Incisor Hypomineralisation. Quality Practice Assistenten, 1(1), 2632.
30
Exterkate, R. & Crielaard, W. (2013). Waterkwaliteit units blijven controleren: veel behandelunits voldoen niet
aan de gestelde normen. Nederlands Tandartsenblad, 68(13), 32-34.
Gambon, D.L. (2013). Voedingsmiddelen in relatie tot tanderosie. Quality Practice. Nascholingstijdschrift voor
Mondhygiënisten, 6, 14-18.
Gorter, R.C. (2013). De psychologie van het samenwerken. Quality Practice. Nascholingstijdschrift voor
Mondhygiënisten, 5(2), 20-23.
Gortzak, R.A.T., Baart, J.A., Allard, R.H.B. & Waal, I. van der (2013). Odontogeen focusonderzoek: een voorstel
voor een meer genuanceerde benadering. Nederlands Tijdschrift voor Tandheelkunde, 120(9), 440-444.
Groot, J. de, Jongh, A. de & Leusink, P. (2013). Geen zin meer in seks? Denk aan psychisch trauma!. Huisarts en
Wetenschap, 56(3), 134-137.
Haverman, T.M., Karagozoglu, K.H., Prins, H-J., Schulten, E.A.J.M. & Forouzanfar, T. (2013). Rapid
prototyping: een veelbelovende methode. Nederlands Tijdschrift voor Tandheelkunde, 120(3), 136-141.
Houtem, C.M.H.H. van & Vermaire, J.H. (2013). Een verhoogde kokhalsreflex. Nederlands Tijdschrift voor
Mondhygiëne, 19(1), 26-29.
Huffels, R.A.M. (2013). Het effect van initële behandeling van chronische adulte parodontitis in de algemene
praktijk. Quality Practice. Nascholingstijdschrift voor Mondhygiënisten, 5(4), 24-30.
Huffels, R.A.M. (2013). Het effect van initële behandeling van chronische adulte parodontitis in de algemene
praktijk. Quality Practice. Nascholingstijdschrift voor Tandartsen, 8(6), 24-30.
Jongh, A. de & Roos, C. de (2013). EMDR: als herinneringen in de weg zitten. Modern Medicine, 3, 85-88.
Jongh, A. de, Baat, C. de, Horstman, M. & Wijk, A.J. van (2013). Subjectieve mondgeurperceptie en sociaal
functioneren. Nederlands Tijdschrift voor Tandheelkunde, 120(4), 194-198.
Karagozoglu, K.H. (2013). Diagnostiek bij mondholtetumoren. Quality Practice. Nascholingstijdschrift voor
Keukenmeester, R.S., Slot, D.E. & Weijden, G.A. van der (2013). Het effect van suikervrije (functionele)
kauwgom op plaque en gingivitis. Quality Practice. Nascholingstijdschrift voor Mondhygiënisten, 5(4), 3237.
Keukenmeester, R.S., Slot, D.E. & Weijden, G.A. van der (2013). Het effect van suikervrije (functionele)
kauwgom op plaque en gingivitis. Quality Practice. Nascholingstijdschrift voor Tandartsen, 8(6), 32-37.
Kraaij, S., Brand, H.S. & Karagozoglu, K.H. (2013). Speekselstenen. Mondhygiënisten Vademecum, 11(5), 1-4.
Loos, B.G. (2013). Nieuwe inzichten in de etiologie en epidemiologie van parodontitis. Quality Practice.
Nascholingstijdschrift voor Tandartsen, 8(6), 8-13.
Loos, B.G. (2013). Nieuwe inzichten in de etiologie en epidemiologie van parodontitis. Quality Practice.
Louropoulou, A. & Weijden, F. van der (2013). Mechanisch reinigen van implantaatoppervlakken. Reinigen ter
voorkoming van peri-implantaite infecties. De Tandartspraktijk, 34(11), 32-35.
Loveren, C. van (2013). Cariogeen of niet cariogeen. Quality Practice. Nascholingstijdschrift voor
Loveren, C. van (2013). De niet-restauratieve cariësbehandeling. Quality Practice. Nascholingstijdschrift voor
Loveren, C. van (2013). Kosteneffectiviteit en cariëspreventie. Nederlands Tijdschrift voor Tandheelkunde,
120(6), 291.
Mellema, E.C., Heuveling, D.A. & Karagozoglu, K.H. (2013). Een rol voor tandartsen bij verdenking op een
melanoom in het aangezicht. Nederlands Tijdschrift voor Tandheelkunde, 120(5), 241-244.
Michels-van Amelsfort, J.M.R., Brand, H.S. & Laar, J.H. van (2013). Orale manifestaties van systemische
sclerose. Nederlands Tijdschrift voor Tandheelkunde, 120(9), 446-450.
Moghimi, M., Forouzanfar, T., Karagozoglu, K.H. & Schulten, E.A.J.M. (2013). Een fulminant beloop van een
dentogene ontsteking. Nederlands tijdschrift voor keel- neus- en oorheelkunde, 19(4), 159-162.
Oliveira, S.C., Slot, D.E. & Weijden, F. van der (2013). Wat is de oorzaak van deze palatumlaesies? De
Tandartspraktijk, 34(11), 27-29.
Özen, B. (2013). Oral and intranasal moderate sedation in pediatric dental patients. Turkiye Klinikleri Journal of
Dental Sciences-Special Topics, 4(3), 27-34.
Palenstein Helderman, W.H. van, Huddleston Slater, J.J.R. & Loveren, C. van (2013). Cariësproces is wel
degelijk omkeerbaar. Samen met ouders gaatjes voorkomen. Nederlands Tandartsenblad, 68(17), 37-39.
Palenstein Helderman, W. van, Huddleston Slater, J. & Loveren, C. van (2013). Fluoride en cariësafname bij
kinderen: fluoridetandpasta veel effectiever dan wordt gedacht. Nederlands Tandartsenblad, 68(14), 32-35.
31
Palenstein Helderman, W. van, Huddleston Slater, J. & Loveren, C. van (2013). Van ziekte en zorg naar gezond
gedrag: vervang periodiek mondonderzoek door 'non-operative caries treatment program'. Nederlands
Tandartsenblad, 68(11), 20-23.
Poorterman, J.H.G. (2013). Bereikbaarheid in de praktijk. Nederlands Tijdschrift voor Tandheelkunde, 2013(4),
179.
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zwelling blijkt zeldzame odontogene tumor. Nederlands Tijdschrift voor Tandheelkunde, 120(11), 599-602.
Rozema, F.R. (2013). Het leek voor anderen. Rede uitgesproken bij de aanvaarding van het ambt van bijzonder
hoogleraar Medische Tandheelkundige Interactie (2013, October 04). Amsterdam: Universiteit van
Amsterdam.
Rijswijk, A., Slot, D.E. & Weijden, G.A. van der (2013). Cannabisgebruik en mondgezondheid. In J.K.M. Aps,
H.S. Brand, J. Duyck, R.J.J. van Es, R. Jacobs & A. Vissink (Eds.), Het Tandheelkundig Jaar 2014 (1e druk) (pp.
251-262). Houten: Bohn Stafleu van Loghum.
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boek Soft-tissue lasers in dental hygiene]. International Journal of Dental Hygiene, 11(3), 231-232.
Soet, J.J. de & Laheij, A.M.G.A. (2013). Infectiepreventie - Veiligheid voor patiënt en assistent. Quality Practice
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Behandeling van (diepe) cariës in melkelementen. In W.E. van Amerongen, L.C. Martens, G. Stel & J.S.J.
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Practice. Nascholingstijdschrift voor Tandartsen, 9(2), 15-19.
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9(2), 48-54.
Strijp, A.J.P. van (2013). Wortelcariës. Een groeiend probleem in een vergrijzende samenleving. Quality
Practice Assistenten, 1(1), 36-43.
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A.J.P. van Strijp (Eds.), Syllabus Mondzorg voor jeugdigen; Module 3: Casus (pp. 34-39). Nieuwegein: NMT,
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A.J.P. van Strijp (Eds.), Facilitatorhandleiding Mondzorg voor jeugdigen: De Derde bijeenkomst-module 3
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Vademecum, 10(9), 1-3.
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Teeuw, W.J. & Loos, B.G. (2013). Parodontitis en hart- en vaatziekten. Quality Practice. Nascholingstijdschrift
Teeuw, W.J. & Loos, B.G. (2013). Parodontitis en hart- en vaatziekten. Quality Practice. Nascholingstijdschrift
Veen, M.H. van der, Waller, E. & Daelen, C.J. van (2013). Novas technologias para diagnostóstico da doença
cárie e seu impacto na prática proffissional. In S.J. Moysés & S. Groisman (Eds.), Pro-Odonto Prevençăo,
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8(6), 20-23.
Velden, U. van der (2013). Voeding en parodontitis. Quality Practice. Nascholingstijdschrift voor
Verrips, G.H.W. (2013). Van gêne to schaamrood. Belangrijke bijdrage [Bespreking van het boek Van gêne to
schaamrood]. Nederlands Tandartsenblad, 68(12), 31.
Vissink, A., Jager-Wittenaar, H., Visser, A., Spijkervet, F.K.L., Weissenbruch, R. van & Nieuw Amerongen, A. van
(2013). Oral medicine 3. Anatomie, fysiologie en diagnostische overwegingen bij smaak- en
reukstoornissen. Nederlands Tijdschrift voor Tandheelkunde, 120(1), 34-39.
32
(2013). Oral medicine 4. Klinische aspecten, gevolgen en behandeling van smaak- en reukstoornissen.
(2013). Oral medicine 5. Voedingsadviezen bij en psychosociale aspecten van smaak- en reukstoornissen.
Waal, I. van der (2013). Blaren in de mond: ken de blaarvormende huid-slijmvliesaandoeningen. De
Waal, I. van der (2013). Een grote radiolucentie in de onderkaak: verwijzing naar de kaakchirurg is geïndiceerd.
De Tandartspraktijk, 34(3), 60-62.
Waal, I. van der (2013). Een vrouw met leukoplakie: verwijzing naar de kaakchirurg is geïndiceerd. De
Waal, I. van der (2013). Gestoorde wondgenezing: vrijwel altijd is verwijzing naar de kaakchirurg geïndiceerd.
De Tandartspraktijk, 34(11), 44-47.
Waal, I. van der (2013). Hemangioom van de onderlip: twee patiënten met verschillende wensen. De
Waal, I. van der (2013). Rode plekken op de tong: wees alert bij een rode plek op de tongrug. De
Waal, I. van der (2013). Tandvleespigmentaties: altijd verwijderen? Verwijzing naar de kaakchirurg is
geïndiceerd. De Tandartspraktijk, 34(4), 48-49.
Waal, I. van der (2013). Verrassende radiolucenties: leerzame diagnostiek. De Tandartspraktijk, 34(9), 48-50.
Waal, I. van der (2013). Zwellingen van het gehemelte: wachten met verwijzen is ongewenst. De
Waal, I. van der (2013). Oral medicine [Bespreking van het boek Oral medicine (2nd edition)]. Nederlands
Tijdschrift voor Tandheelkunde, 120(2), 120.
Waal, I. van der & Leemans, C.R. (2013). Aandoeningen van de mondholte. In N. de Vries, P. van de Heyning &
C.R. Leemans (Eds.), Leerboek keel-neus-oorheelkunde en hoofd-halschirurgie. - 2e herz. druk (pp. 261272). Houten: Bohn Stafleu van Loghum.
Waal, I. van der & Leemans, C.R. (2013). Orale pathologie bij kinderen. In W.E. van Amerongen, L.C. Martens,
G. Stel & J.S.J. Veerkamp (Eds.), Kindertandheelkunde 2. - 2e herz. druk (pp. 36: 105-116). Houten: Bohn
Stafleu van Loghum.
Waal, S.V. van der (2013). Endodontische desinfectie: er valt nog veel te onderzoeken. NVvE, 27-01-2013. Het
Kanaal.
Warnsinck, C.J., Shemesh, H. & Lobbezoo, F. (2013). Persisterende pijn na endodontische behandeling.
Weijden, F. van der & Slot, D.E. (2013). De effectiviteit van tandenpoetsen. Dental Tribune, 5, 15-16.
Weijden, F. van der & Slot, D.E. (2013). How effective is toothbrushing? RDH Magazine, 33(2).
Weijden, F. van der & Slot, D.E. (2013). How effective is toothbrushing? Suggestions for improving plaque
reduction scores. RDH Magazine, 2, 86-87.
Weijden, G.A. van der & Rosema, N.A.M. (2013). Patiënten die langdurig spoelen met Halita of 2 weken
spoelen met 0,2% chloorhexidine krijgen aanslag op hun gebitselementen. Wat is er aan te doen om dit te
voorkomen? Mondhygiënisten Vademecum, 11(6), 1-3.
Wiegman, H. (2013). Het roer moet om. Nederlands Tandartsenblad, 68(2), 16-17.
Wit, R. de, Berg, M.A.G. van den, Tuut, M.K., Amelsfoort, P. van, Beerthuizen, A., Berg, J.S.P. van den, Bomhof,
M., Bont, L.G.M. de, Boven, R. van, Dekker, F., Engels, J.H.B., Helder, J.C., Huygen, F., Koopman, J.S.H.A.,
Lever-Wiersema, P., Lobbezoo, F., Lynch, H., Mooij, J.J.A., Mulleners, W., Nauta, N., Passchier, J., Ru, J.A.
de, Samwel, H., Simon, M., Stegenga, B., Tjakkes, G-H., Tusscher, M.P.M. ten, Vanneste, J., Visscher, C.M.,
Warnsinck, J. & Zuurmond, W.W.A. (2013). Multidisciplinaire Richtlijn “Chronische Aangezichtspijn”, 136
pp.http://www.hoofdpijnpatienten.nl/images/stories/PDF/Richtlijnen/Richtlijnen_aangezichtspijn/Richtlijn
_pdf/Richtlijn%20aangezichtspijn%2021112013%20DEFINITIEF.pdf. Amersfoort: Nederlandse Vereniging
van Hoofdpijnpatiënten, authorized 21-11-2013.
Publications for the general public
Brand, H., Ouzzine, R. & Bots, C. (2013). Speekselsubstituten: voor verbetering vatbaar! Ogenblikje, 26(105),
16-17.
33
Eijkman, M.A.J. (2013, January 05). Kronen en bruggen gaan jaren mee, maar permanent zijn ze niet. NRC
Handelsblad.
Eijkman, M.A.J. (2013, February 03). Tandarts kent patiënten slecht. NRC Handelsblad.
Eijkman, M.A.J. (2013, May 24). Ouders: bewaak zelf kindergebitten. NRC Handelsblad.
Eijkman, M.A.J. (2013, September 14). Röntgenfoto van de tanden verraadt iemands leeftijd. NRC Handelsblad
Eijkman, M.A.J. (2013, October 12). Mondpiercings geven ellende. NRC Handelsblad.
Eijkman, M.A.J. (2013, October 18). Deelnemers Olympische Spelen verwaarlozen hun gebit. NRC Handelsblad.
Strijp, A.J.P. van (2013). Zo zorg je voor een stralende lach zonder gaatjes. J/M Ouders, 1, 1387-1099.
Patents
Bikker, F.J., Kaman-van Zanten, W.E., Hays, J.P. & Veerman, E.C.I. (2013) Detecting the presence of
periopathogen e.g. Porphyromonas gingivalis in sample involves incubating the sample with substrate
comprising dipeptide consisting of specific amino acids, and detecting cleavage of the substrate,
WO2013025099-A1, 21 Feb 2013.
Veerman, E.C.I., Valentijn-Benz, M., Hof, W. van 't & Bikker, F.J. (2013) Protection of materials by sphingosine
based compounds, P97560PC00, 1 Oct 2013.
Grants: current projects with external funding
Alvarez Rodriguez, E. The additive effects of plasma levels of omega-3 en-6 poly-unsaturated fatty acids on the
response to initial periodontal therapy. A grant supplied by NVvP €4.200,-Bikker, F.J. & Veerman, E.C.I., Defensie/TNO. Application of antimicrobial peptides as anti-warfare
therapeutics. 2010-2014: € 280.000.
Cate, J.M. ten, Academy Professor, Royal Netherlands Academy of Arts and Sciences (KNAW), total €
1.000.000,-period 2008-2013.
Cate, J.M. ten, Crielaard, W., Loos, B.G. & Veerman, E.C.I. “Oral health” (2011-2015) University of
Amsterdam/Research Priority Area, € 1.308,000.-.
Cate ten J.M. ten, Crielaard W., Soet J.J. de & Loveren C. van STW project. Seeing is believing. M.H. van der
Veen & C.M.C. Volgenant. Start October 2010 - October 2016, € 500.000,-.
Crielaard, W., Preventive Dentistry, Periodontology, Oral Biochemistry, Cariology,, TIFN Oral Health (20122016): Public Private Partnership funded by the Dutch Ministry of Economic Affairs, Wrigley, Philips
Research, Cargill, GlaxoSmithKline, TNO, WUR & ACTA (Total investment 5.2 M€).
Crielaard, W., Zaura, E. & Buijs, M.J. EU (FP7) grant for the project no. 241446: ANTIRESDEV. “The effects of
antibiotic administration on the emergence and persistence of antibiotic-resistant bacteria in humans
and on the composition of the indigenous microbiotas at various body sites”. Total budget for ACTA:
€359.036,-. Start: November 1, 2009 – April 30, 2013. Coordinator: University College London.
Crielaard, W. & Krom, B.P. NWO Middelgroot - Studying Dynamics in complex Microbial biofilms. 2013-2017
€164,000.
Crielaard, W. A Blue World Halitosis – Development and use of halitosis model 2013 (k€30).
Crielaard, W. & Fernandez, M. NGen Ardox - Exploiting Ardox-x® TECHNOLOGY in preventing and treating
polymicrobial biofilm infections in the oral cavity. 2011-2015 (k€ 400).
Deng, D.M., Cate, J.M. ten & Crielaard, W. KNAW Grant 11CDP012 Samenwerking West China School of
Stomatology Caries Prevention Potential of Functionalized nano-Hydroxyapatite under Microbiological
Challenges. € 59795,- 2011-2015.
Deng, D.M., Wesselink, P.R. & Crielaard, W. KNAW Grant 12CDP05 Samenwerking Guanghua school of
Stomatology, Sun Yat-sen University Guang-zhou Novel molecular methods to rediscover the role of
microorganisms in persistent apical periodontitis k€ 60,- 2012-2016.
Exterkate, R.A.M., Crielaard W. & Cate, J.M. ten. Development and evaluation of relevant dental in vitro
biofilm models for the screening of new active compounds. Colgate, USA (k€140). Reports: Colgate A2012-359-OC- January 2013; Colgate A-2012-359-OC-August 2013.
Exterkate, R.A.M., Wit, W.E.A.J. de, & Crielaard W. Effect of Airfloss on interproximal plaque, a typodont
study. Philips, USA (k€46,5). Report: data was reported on a weekly basis. No written report, only transfer
of data.
34
Exterkate, R.A.M., Willems, H.M.E., Wit, W.E.A.J. de, Horst, J. van der, & Cate, J.M. ten. Effect of
experimental toothpastes on the de-/remineralization of enamel. GABA, Switzerland. Report: GABA pHcycling GARD-P1202F11 July 2013 (k€ 46).
Forouzanfar, T. & Jager, D.H.J. ‘Klinische inventarisatie van implantologie bij Sjögrenpatiënten in Nederland’.
NUTS OHRA. € 150.000,- Start: December 2013, end: December 2016.
Gorter R.C. & Wismeijer, D. International Team for Implantology (ITI): Digital dentistry in practice; on dentists’
interaction with technological transformations. First part of PhD project funding, collaboration of Social
Dentistry and Oral Implantology. February 2012 – December 2013: 110.000,- euro.
Krom, B.P. Interspecies interactions as targets to fight burnwound infections, Nederlandse Brandwonden
Stichting, € 194.162,- start 01-09-2012, end 31-8-2014.
Krom, B.P. ERC starting grant collaborator, QuorumProbes, Dr. Michael Meijler PI, k€ 80. Start: October 2013,
end: October 2014.
Loos, B.G. “Microbiome of peri-implant sulcus/pocket: A pyrosequencing study on the microflora of
periimplant health and disease”.(2011-2013). A grant price by the Deutsche Gesellschaft fur
Parodontologie, €50,000,-.
Loos, B.G. “Regenerative surgical treatment of peri-implant osseous defects - a multicenter randomized
prospective clinical study” (2011-2013). A grant supplied by Tigran AB, Sweden, € 20,000,-.
Loos, B.G. Tigran porous titanium granules in surgical peri-implantitis treatment, in collaboration, € 20.000,2011-2014.
Loos, B.G. “The effect of daily dietary intake of dried juice concentrates of fruit, vegetables and berries (Juice
Plus+) upon periodontal outcomes in chronic periodontitis: a multi-centre RCT” (2010-2013) A grant
supplied by JuicePlus, USA, (ENURGISE) € 71,830,-.
Loveren van, C. &Verrips, G.H.W. ACTA-Menzis: Preventie van caries bij kinderen at risk. 01-02-2011 tot 0102-2014. Menzis € 162.750.
Schoonheim-Klein, M.E. NIH (2011-2016) in cooperation with Harvard, UCSF and Creighton US$ 100.000,-.
Sluijs, E. van der. (2012-2013) The effect of rinsing or drinking water on morning bad breath. A grant supplied
by NVvP € 2.400,--.
Soet de, J.J. & Crielaard, W. Biofilm composition and secondary caries in situ and in vivo. $ 955,606 from NIH.
Start: September 2010 - September 2014.
Veerman, E.C.I. & Bikker, F.J., NWO-ZONMW Exploiting Staphylococcus aureus sortase for anti-infective
purposes. 2010-2014: € 336, 923.
Veerman, E.C.I., Bolscher, J.G.M., Gibbs, S.,& Schepers, R. Technology Foundation STW. Novel saliva-derived
peptides for state-of-the-art clinical wound-healing applications. 2010-2014: € 641.317.
Veerman, E.C.I., NWO-ALW. How histatin enhances wound closure: structural and cellular aspects. 2010-2014:
€ 280.013.
Veerman, E.C.I., Ligtenberg, A.J.M. & Bolscher, J.G.M. Technology Foundation STW. Development of
protective coatings. € 836,397.
Veerman, E.C.I. & Brand, H.S. Topschool Institute of Food and Nutrition. Saliva and oral health: 1 AIO, 0.05
UD.
Weijden, G.A. van der, Rosema, N.A.M., Slot, D.E., Berchier, C.E., Versteeg, P.A., Hoenderdos, N.L., Velden,
U. van der & Winkelhoff, A.J. van. Prevention of plaque and gingivitis: A 6-months placebo-controlled highbioavailability-cpc-mouthrinse study. (DENTAID) €78.200,-.
Weijden, G.A. van der, Rosema, N.A.M., Hoenderdos, N.L., Anraat, G. van, Berchier, C.E., Versteeg, P.A. &
Slot, D.E.. Preventive strategies in order to obtain healthy teeth for life. (ZonMW). € 163.985,-.
Weijden, G.A. van der & Loos, B.G. TIFN WP1 en WP2 clinical studies, € 139.000,-Weijden, G.A. van der. Unrestricted Educational Grant € 74.940,-Weijden, G.A. van der. TNO Roquette / Baker € 60.306,-Weijden, G.A. van der. TNO Sunstar / Sorbet € 56.520,-Weijden, G.A. van der. GABA, Halitosis € 10.478,-Weijden, G.A. van der. P&G “ERBA” € 21.924,-Wesselink, P.R., Ministery OCW € 850.000,-. Simodont project for three years 2008-2010. Extended till 2013
by decision of OCW in October 2011.
35
Indicators of Esteem
Book editorship
Aps, J.K.M., Brand, H.S., Duyck, J., Es, R.J.J. van, Jacobs, R. & Vissink, A. (Eds.). (2013). Het Tandheelkundig Jaar
2014, 1e druk. Houten: Bohn Stafleu van Loghum.
Baart, J.A. & Brand, H.S. (Eds.). (2013). Lokale anesthesie in de tandheelkunde. Tweede geheel herziene druk.
Houten: Bohn Stafleu van Loghum.
Loveren, C. van (Ed.). (2013). Toothpastes (Monograph in oral science, vol. 23), 158 pp. Basel: S. Karger AG.
Memberships of editorial board
Aartman, I.H.A..:
Bloemena, E.:
Bloemena, E.:
Bloemena, E.:
Bolscher, J.G.M.:
Bonifacio, C.C.:
Brand, H.S.:
Brand, H.S.:
Cate, J.M. ten:
Cate, J.M. ten:
Cate, J.M. ten:
Cate, J.M. ten:
Cate, J.M. ten:
Cate, J.M. ten:
Crielaard, W.:
Diermen, D.E. van:
Diermen, D.E. van:
Eijkman, M.A.J.:
Gorter, R.C.:
Heijden, G.J.M.G. van der:
Jongh, A. de:
Jongh, A. de:
Laine, M.L.:
Loos, B.G.:
Loos, B.G.:
Loveren, C. van:
Özen, B.:
Raber-Durlacher, J.E.:
Rosema, N.A.M..:
Shemesh, H.:
Shemesh, H.:
Slot, D.E.:
Veerkamp, J.S.J.:
Veerman, E.C.I.:
Waal, I. van der:
Waal, I. van der:
Waal, I. van der:
Waal, I. van der:
Waal, I. van der:
Waal, I. van der:
Waal, I. van der:
Waal, I. van der:
Waal, I. van der:
Weijden, G.A. van der:
Wesselink, P.R.:
36
European Journal of Dental Education.
ISRN Gastroenterology.
Scandinavian Journal of Gastroenterology.
World Journal of Gastrointestinal Oncology.
Chiang Mai University Journal of Natural Sciences.
APCD journal.
Nederlands Tijdschrift voor Tandheelkunde.
Het Tandheelkundig Jaar.
European Journal of Oral Sciences.
International Journal of Dentistry.
Journal of Dental Research.
Journal of Oral Microbiology.
Odontology.
The Chinese Journal of Dental Research.
Microbiology - SGM.
Quality Practice. Nascholingstijdschrift voor Mondhygiënisten.
Quality Practice. Nascholingstijdschrift voor Tandartsen.
Journal of Medical Case Reports.
European Journal of Psychotraumatology.
Journal of EMDR Practice and Research.
Current Oral Health Reports – issue Epidemiology.
Journal of Clinical Periodontology.
Oral Health and Preventive Dentistry.
American Journal of Medical Sciences and Medicine.
Mediators of Inflammation, special issue Alimentary Mucositis: Mediators,
Mechanisms and emerging therapies.
International Journal of Dental Hygiene.
Journal of Endodontics.
International Endodontic Journal.
Mondhygiënisten Vademecum.
Odontology.
Acta Stomatologica Croatica.
European Journal of Cancer.
Journal of Dentistry University of Sao Paolo.
Journal of Oral and Maxillofacial Surgery.
Medicina Oral.
Minerva Stomatologica.
Nederlands Tijdschrift voor Geneeskunde.
Oral Health and Preventive Dentistry.
Oral Oncology.
Deutsche Zahnärztliche Zeitschrift.
Wesselink, P.R.:
Wesselink, P.R.:
Wesselink, P.R.:
Wu, M.K.:
Zaura, E.:
Zaura, E.:
Endodontic Practice Today.
Endodontie.
Caries Research.
Frontiers in Microbiology.
Invited speakers at (inter)national scientific congresses or symposia
Baart, J.A. (2013, September 04). Non-neoplastic salivary gland disorders: diagnosis and management.
Amsterdam, the Netherlands, European Meeting on Oral Diseases.
Bloemena, E. (2013, September 05). Cytology and histopathology of neoplastic and non-neoplastic salivary
gland lesions. Amsterdam, the Netherlands, European Meeting on Oral Diseases.
Boutsioukis, C. (2013, November 29). 1. A fluid-dynamics approach to root canal irrigation; 2. Safety issues Irrigant extrusion. Athens, Greece, 1st International Congress of Endodontics, Hellenic Society of
Endodontics.
Brand, H.S. (2013, April 18). Accidents can happen. Hilversum, the Netherlands, Afscheidssymposium
professor C. de Baat, Stichting Beeld en Geluid.
Brand, H.S. (2013, April 12). De tandarts in beeld. Amsterdam, the Netherlands, Nederlands Filmmuseum.
Cate, J.M. ten (2013, May 06). 1. Research trends in dentistry. 2. Fluoride-antibacterial approaches to improve
caries control. 3. Rational use of fluorides in caries prevention. Pattaya, Thailand, 11th Dental Faculty
Consortium of Thailand (DFCT), Thammasat University.
Cate, J.M. ten (2013, December 12). Biofilms, a new approach to dental plaque. London, UK, British Dental
Association (BDA).
Cate, J.M. ten (2013, April 19). Biofilms: recent advances and future challenges. Basel, Switzerland, GABA
Celebrates 50 years of Caries prevention.
Cate, J.M. ten (2013, September 12). Capita selecta biofilms. Chicago, USA, Wrigley Scientific Institute.
Cate, J.M. ten (2013, May 08). Fluoride-antibacterial approaches to improve caries control. Singapore,
Singapore dental association.
Cate, J.M. ten (2013, May 10). Fluoride-antibacterial approaches to improve caries control. Sandton, JandJ
advisory Group.
Cate, J.M. ten (2013, September 26). Mode of action of fluorides. Shanghai, China, Unilever caries prevention
symposium.
Cate, J.M. ten (2013, July 03). New approaches – what is there beyond fluoride? Liverpool, UK, Caries
prevention beyond fluoride A report on the Colgate-sponsored Satellite Symposium, European
Organisation for Caries Research (ORCA) Congress.
Cate, J.M. ten (2013, May 11). Opportunities for caries prevention with novel antimicrobial agents. Kuale
Lumpur, Malaysia, 35th Asian Dental Pacific Conference (ADPC).
Cate, J.M. ten (2013, March 21). Pivotal issues for effective therapeutics. Seattle, USA, IADR World congress,
symposium The Buzzing World of Oral Biofilms and Dental Caries.
Cate, J.M. ten (2013, June 27). Rational use of effective therapeutics. Seefeld, Germany, 3MESPE.
Cate, J.M. ten (2013, November 08). Rational use of fluorides in caries prevention. Helsinki, Finland, Finish
Dental Society.
Cate, J.M. ten (2013, August 01). Theoretical aspects of enamel remineralization. Cincinnati, USA, P&G.
Crielaard, W. (2013, September 09). Analysis of plaque by high throughput sequencing techniques. Bath, UK,
British Society for Oral and Dental Research.
Crielaard, W. (2013, September 23). Effects of different antibiotics on faecal microbiome profiles by 16S rRNA
gene amplicon sequencing. Kosice, Slovakia, 36th International Congress, Society for Microbial Ecology and
Disease.
Crielaard, W. (2013, April 22). Genomics and the undergraduate dental curriculum. Glasgow, ABSTD and OMIG
–Spring 2013 joint meeting.
Danser, M.M. (2013, September 17). Micro organisms and periodontal treatment. Moscow, Russia,
International Conference of Dental Hygienist.
Eijkman, M.A.J. (2013, December 13). Leerzame missers en mislukkingen. Apeldoorn, the Netherlands, Vrijdag
de 13e. Wat er fout kan gaan in de tandartspraktijk… en hoe het op te lossen? Dr. G.J. van Hoytema
Stichting.
37
Elfrink, M.E.C. (2013, March 22). Deciduous Molar Hypomineralisation. Doorn, the Netherlands, Nederlandse
Vereniging voor Kindertandheelkunde (NVvK) congress.
Elfrink, M.E.C. (2013, September 20). Milchmolaren-Hypomineralisation - klinisches ercheinungsbild, prävalenz
und mögliche ursachen (Deciduous Molar Hypomineralisation - clinical appearance, prevalence and
determinats for its occurance). Gießen, Germany, Deutsche Geselschaft für Kinderzahnheilkunde (DGKiZ).
Gorter, R.C. (2013, May 24). Tandarts en burnoutrisico: no time to change? Oostende, Belgium, Verbond van
Vlaamse Tandartsen.
Heijden, G.J.M.G. van der (2013, September 25). Integriteit in de wetenschap. Amsterdam, the Netherlands,
Senaat UvA, Spui 25.
Krom, B.P. (2013, May 20). Bacterial hitch-hiking; Candida - Staphylococcus interactions in the oral cavity.
Glasgow, UK, 2nd Fungal Biofilms Meeting.
Krom, B.P. (2013, December 08). Bacterial-fungal interactions: a federative field for fundamental and applied
microbiology. Roscoff, France, Jacques Monod Conference.
Krom, B.P. (2013, September 09). The role of fungi in a healthy oral ecology. Ghent, Belgium, Eurobiofilms
2013.
Laine, M.L. (2013, May 02). Saliva in the diagnosis of dental diseases. Amsterdam, the Netherlands, Russian
federation for dental hygienist.
Laine, M.L. (2013, September 20). Submucosal microbiome of peri-implant health and disease. Erfurt,
Germany, Deutsche Gesellschaft für Parodontologie (DGB).
Laine, M.L. (2013, October 27). Genetic factors and periodontal epidemiology. Geneva, Switzerland, European
Research Group of Oral Biology (ERGOB).
Loos, B.G. (2013, March 10). General health in relation to oral health – Current status and future trends.
Amsterdam, the Netherlands, International symposium Emerging trends in oral healthcare. Philips Oral
Healthcare Symposium Oral health in the 21st century. What is next?.
Loos, B.G. (2013, March 13). Oral infections, i.c. periodontitis, affect general health. Rome, Italy, School of
Dentistry, Sapienza University.
Loos, B.G. (2013, June 12). Periodontitis and cardiovascular disease: systemic and genetic connections.
Connecting the past with the future. Buffalo, NY, USA, Symposium 50th anniversary UB Oral Biology
Graduate program, University at Buffalo (SUNY).
Loos, B.G. (2013, October 15). Periodontitis and other oral infections are risk factors for cardiovascular
diseases and diabetes. Academic Medical Center, University of Amsterdam, AMC Ruysch lecture.
Louropoulou, A. (2013, October 19). Diagnostiek van peri-implantaire infecties en de professionele reiniging
van tandheelkundige implantaten. Knokke, Belgium, Congres Vlaamse Wetenschappelijke Vereniging van
Tandartsen.
Loveren, C. van (2013, October 09). 1. Stagnation in prevention. Where do we go? 2. Prevention of oral health
risk in elderly and compromised individuals. Budapest, Hungary, World Conference on Preventive
Dentistry.
Loveren, C. van (2013, July 03). Education of undergraduate dental students from ACTA in caries prevention.
London, UK, ORCA Education Platform, European Organisation for Caries Research Congress.
Raber-Durlacher, J.E. (2013, April 25). Periodontal status and bacteremia with oral viridans streptococci and
coagulase negative staphylococci in allogeneic hematopoietic stem cell transplantation recipients. San
Antonio, American Academy of Oral Medicine.
Rosema, N.A.M. (2013, September 14). 1. 100th anniversary of the Dental Hygienist – trends and perspectives
for the next 100 years. 2. Post-treatment hygiene protocol in Western Europe. Poznan, Poland, Central
Europe Dental Exhibition.
Rosema, N.A.M. (2013, May 04). 1. Sodium bicarbonate in dentistry over the years. 2. Current literature on
Parodontax. London, England, Advisory board meeting GSK.
Schulten, E.A.J.M. (2013, September 05). Management of odontogenic cysts and tumours. Amsterdam, the
Netherlands, European Meeting of Oral Diseases.
Schulten, E.A.J.M. (2013, September 19). Management of odontogenic tumours. Amsterdam, the Netherlands,
European Head and Neck Course.
Shemesh, H. (2013, May 23). 1. Dentinal defects after root canal treatment; 2. Quality of root canal treatments
performed by undergraduate students. Tokyo, Japan, International Federation of Endodontic Associations
(IFEA).
Shemesh, H. (2013, June 01). Cracks and fractures after endodontic procedures. Berlin, Germany, 13th session
of the German Endodontic Society.
38
Shemesh, H. (2013, August 12). Dentinal defects after root canal preparation. China, University of Shanghai
and University of Beijing.
Shemesh, H. (2013, August 15). Dentinal defects after root canal preparation. China, University of Shanghai
and University of Beijing.
Shemesh, H. (2013, April 17). Outcome of root canal treatments as determined by CBCT. Honolulu, Hawaii,
American Association of Endodontology.
Shemesh, H. (2013, September 13). Outcome of root canal treatments with CBCT. Lisbon, Portugal, European
Society of Endodontology biannual session.
Shemesh, H. (2013, October 31). Root canal treatments. Tel Aviv, Israel, Annual dental conference, Israeli
Dental Association.
Slot, D.E. & Weijden, G.A. van der (2013, April 05). How to perform a systematic review? Cairo, Egypt, 2 day
workshop Cairo University.
Slot, D.E. (2013, August 16). 1. The effect of 1% chlorhexidine gel and 0.12% dentifrice gel on plaque
accumulation: a 3-day non-brushing model. 2. How to deal with tooth sensitivity in daily practice. Cape
town, South Africa, SUNSTAR, ISDH symposium.
Slot, D.E. (2013, October 30). Dentistry is teamwork! St. Petersburg, Russia, Russische mondhygiënisten
vereniging.
Slot, D.E. (2013, May 11). 1. Do lasers/photodynamic therapy have a role in non surgical periodontal
treatment? 2. Finding evidence for evidence based decision making. Bari, Apulia, Italy, V Congresso
Nazionale SISIO.
Slot, D.E. (2013, August 15). Floss or Lie, how to read and interpreted scientific literature. Cape town, South
Africa, ISDH symposium.
Slot, D.E. (2013, October 19). Hoe kan een patiënt zijn implantaat het beste reinigen? Knokke, Belgium,
Congres Vlaamse Wetenschappelijke Vereniging van Tandartsen.
Slot, D.E. (2013, October 31). How to brush evidence based? Moscow, Russia, Vereniging Preventieve
Tandheelkunde Rusland.
Slot, D.E. (2013, May 09). Interdental cleaning with an evidence based approach. Naples, Italy, University
Federico II.
Slot, D.E. (2013, January 28). Maintain dental implants, what can patients and the professional do. Curacao,
Intercongress.
Slot, D.E. (2013, May 18). The independent dental hygienist in the Netherlands. Brussel, Belgium, BVP.
Strijp, A.J.P. van (2013, July 03). Education of undergraduate dental students from ACTA in caries prevention.
Veerkamp, J.S.J. (2013, November 26). Behaviour management in pediatric dentistry. United Arab Emirates,
Dubai Dental School.
Veerkamp, J.S.J. (2013, November 29). Dental anxiety, pain and their management. Al Ain, Dubai, United Arab
Emirates, Symposium 1st Horizons in Dentistry.
Veerkamp, J.S.J. (2013, January 19). Managing pain and its consequences. Zürich, Switzerland, Schweizer
Lachgastagung (SVK).
Veerkamp, J.S.J. (2013, February 03). Sedation, guidance and management. Helsinki, Finland, Sedation Course
University of Helsinki.
Veerkamp, J.S.J. (2013, March 23). Wachstum und Entwicklung, Kinderpsychologie, Verhaltensmanagement
und Pädiatrie. Münster, Germany, Masterstudiengang Kinderzahnheilkunde.
Waal, I. van der (2013, November 04). Current concepts of oral potentially malignant disorders; diagnosis and
management. Bangkok, Thailand, 1st International Symposium Oral Diseases Group.
Waal, I. van der (2013, September 05). Lichen planus and lichenoid lesions; leukoplakia; histopathology of
odontogenic cysts and tumors. European Meeting of Oral Diseases. Amsterdam, the Netherlands, European
Meeting Oral Diseases.
Waal, I. van der (2013, May 17). Oral leukoplakia; an update; the nonsquamous cell oral cancers. Santiago de
Compostela, Spain, Spanish Association of Oral Medicine.
Weijden, G.A. van der (2013, April 28). Maintenance around implants, airpolishing, ultrasonic treatment and
dentine hypersensitivity. Curacao, Your yearly update in Dentistry.
Weijden, G.A. van der (2013, October 17). Safety and efficacy of powered toothbrushes. Semi Annual Meeting
Israeli Society of Periodontology and Osseointegration: The Soft Tissue – The Key to Success, Tel Aviv,
Israel.
Weijden, G.A. van der (2013, April 11). Safety and efficacy of powered toothbrushes. Kronberg, Germany, KOL
event.
39
Wesselink, P.R. (2013, January 18). The role of CBCT in endodontic treatment planning and outcome. Basel.
Switzerland, Annual congress Swiss Endodontic Society.
Wesselink, P.R. (2013, September 12). 1. Chairside diagnosis and treatment decisions; 2. Current criteria used
for success-failure observations in endodontics, are they reasonable? Lisbon, Portugal, 16th ESE biennial
congress.
Wesselink, P.R. (2013, June 21). The role of CBCT in endodontic treatment planning and outcome. Toronto,
Canada, Annual Symposium, University of Toronto.
Zaura, E. (2013, September 23). Effects of different antibiotics on faecal microbiome profiles by 16S rRNA gene
amplicon sequencing. Kosice, Slovakia, 36th International Congress, Society for Microbial.
Membership academies
Cate, J.M. ten
Academy professor. Royal Netherlands Academy of Arts and Sciences (KNAW):
(2008, January 01 - 2013, December 31).
Scientific awards/honours
Akcan, V., Alhamrany, Z., Bax, B., Blok, G., Borg, K., Demir, E., Dijkhuis, K., Hennequin, N. & Richardson, M.
(2013). NVM Poster award 2013: Is plaque te gummen? Het effect van Softpicks. IT-groep Amersfoort 3:
Amersfoort, the Netherlands (2013, April 12).
Blom, T., Slot, D.E., Quirynen, M. & Weijden, G.A. van der (2013). SUNSTAR world dental hygienist award,
student research category for: The effect of mouthrinses on oral malodor: a systematic review. Int J Dent
Hyg. 2012 Aug.10(3): 209-22. International Symposium on Dental Hygiene: Cape Town, South Africa (2013,
August 16).
Cate, J.M. ten (2013). Honorary professor. West China School of Stomatology: (2013, February 01).
Crielaard, W. (2013). Honorary professor Oral Biosciences. Department of Oral Biosciences, Faculty of
Dentistry: University of Hong Kong, China.
Crielaard, W. (2013). Visiting professor Oral Microbiology School of Stomatology, Sun Yat Sen University,
Guangzhou, China.
Duijster, D. (2013). GSK-IOT Best presentation award 2013: Pathways between behavioural, psychosocial and
environmental determinants of childhood dental caries. IOT Dental Research Meeting: Lunteren, the
Netherlands (2013, February 07 - 2013, February 08).
Putten, G.J. van der, Brand, H.S., Schols, J.M.G.A. & Baat, C. de (2013). Vereniging voor Biologie van de Mond
Research Prize 2013 with article: The diagnostic suitability of a xerostomia questionnaire and the
association between xerostomia, hyposalivation and medication use in a group of nursing home residents.
Clinical Oral Investigations, 15: 185-192 (2011). IOT Dental Research Meeting 2013: Lunteren, the
Netherlands (2013, February 07 - 2013, February 08).
Scheres, N. (2013). Eurobiofilms 2013 poster awards 3rd prize: Phagocytosis of Candida albicans-adhered
Staphylococcus aureus. Eurobiofilms 2013 conference: Ghent, Belgium (2013, September 09 - 2013,
September 11).
Slot, D.E., Rosema, N.A.M., Hennequin-Hoenderdos, N.L., Versteeg, P.A., Velden, U. van der & Weijden, G.A.
van der (2013). SUNSTAR world dental hygienist award, research category for: The effect of 1%
chlorhexidine gel and 0.12% dentifrice gel on plaque accumulation: a 3-day non-brushing model. Int J Dent
Hyg. 2010 Nov. 8(4): 294-300. International Symposium on Dental Hygiene: Cape Town, South Africa (2013,
August 16).
Zandbergen, D., Slot, D.E., Cobb, C.M. & Weijden, G.A. van der (2013). Poster award: The clinical effect of SRP
ant the concomitant administration of systemic amoxicillin and metronidazole: two systematic reviews.
Dentsply Student Clinician Program 2013: Bella Center, Copenhagen (2013, April 20).
Vermaire, J.H. (2013). WTA Hamer-Duijvenszprijs voor proefschrift: "Optimizing Oral Health; towards a
tailored, effective and cost-effective dental care”. Najaarscongres Nederlandse Vereninging van Tandartsen
(NVT): the Netherlands (2013, November 01).
Waal, I. van der (2013). Honorary membership. Spanish Association of Oral Medicine: Santiago de Compostela,
Spain (2013, May 17).
Organisation of (inter)national congresses and symposia
40
Brand, H.S.: Board member Salivary Research Group, International Association of Dental Research (IADR).
Eijkman, M.A.J. Organizer. Symposium Onder Professoren VIII, Dr. G.J. van Hoytema Stichting: Enschede, the
Netherlands (2013, January 25).
Houtem, C.M.H.H. van: Organizer. Voorjaarscongres NVvK & VBTGG: "Bijzondere Tandheelkunde: een lust én
een last?": Doorn, the Netherlands (2013, March 22 - 2013, March 23).
Houtem, C.M.H.H. van: Organizer. VBTGG: "(Nooit) te oud om te leren?" Psychopathologie bij kwetsbare
ouderen: Utrecht, the Netherlands (2013, November 22).
Jongh, A. de: Organizer. Vereniging EMDR Nederland, EMDR congress: "Research track": Nijmegen, the
Netherlands (2013, April 20).
Jongh, A. de: Organizing committee. Anxiety Disorders and Depression Conference (ADAA): "Current research
on Eye Movement Desensitization and Reprocessing (EMDR) therapy": San Diego, USA (2013, March 28).
Raber-Durlacher, J.E.: Organizer MASCC/ISOO Annual Symposium Berlin, Germany, June 23-26, 2013.
Shemesh, H.: Organizing committee. Voorjaarscongres NVvE, Trauma: een ongeluk zit in een klein hoekje:
Amsterdam, the Netherlands (2013, March 23).
Waal, I. van der, Schulten, E.A.J.M., Brouns, E.R.E.A. & Steenbergen, T.J.M. van (2013). Organizing members.
European Meeting on Oral Diseases; diagnosis and management: Amsterdam, the Netherlands (2013,
September 04 - 2013, September 06).
Other (inter)national scientific functions
Allard, R.H.B.:
Bloemena, E.:
Brand, H.S.:
Cate, J.M. ten:
Cate, J.M. ten:
Cate, J.M. ten:
Diermen, D.E. van:
Gorter, R. C.:
Gorter, R. C.:
Houtem, C.M.H.H. van:
Krom, B.P.:
Laine, M.L.:
Laine, M.L.:
Loos, B.G.:
Loos, B.G.:
Loos, B.G.:
Loos, B.G.:
Loos, B.G.:
National association IT representative International Association of Oral and
Maxillofacial Surgery.
Member ESP Working Group Head and Neck Pathology.
Board member Salivary Research Group, International Association of Dental
Research (IADR).
Honorary professor Universidad Peruana Cayetano Heredia, Lima, Peru.
Honorary professor University of Hong Kong, China.
Member advisory panel Wrigley Science Institute, Chicago, USA.
Consultant World Workshops in Oral Medicine; working group: Dental
treatment of Medically Complex Patients. American Academy of Oral
Medicine (AAOM). Contact through internet-based meetings.
Kamer Mondzorg – werkgroep 2. Richtlijnen Tandheelkunde. NMT (2013).
Executive board member ADEE (since 2013).
Member working group GRADE.
Member
congress
committee
Nederlandse
Vereniging
voor
Kindertandheelkunde (NVvK) en Vereniging tot Bevordering der
Tandheelkundige Gezondheid voor Gehandicapten (VBTGG).
Reviewer Atip-Avenir Programme, France, April.
External reviewer for international grant application Hong Kong Scientific
Evaluation Board.
External reviewer of appointment of senior lecturer P. Mäntylä University of
Helsinki, Finland.
Member international scientific committee 46th meeting of the Continental
European Division of the International Association for Dental Research (CEDIADR), September 4-7-2013, Florence, Italy.
Councilor Board CED (Continental European Division) and CED representative
PER (Pan European Region) International Association of Dental Research
(IADR).
Ad hoc reviewer Polish Institute of Sciences.
Board member Society for the advancement of Natural Sciences, Medicine
and Surgery, University of Amsterdam, the Netherlands.
Examiner PhD committee Faculty of Dental Medicine, Sapienza University,
Rome, Italy.
Board member Multinational Association for Supportive Care in Cancer
(MASCC).
41
Rosema, N.A.M.:
Shemesh, H.:
Shemesh, H.:
Soet, J.J. de:
Soet, J.J. de:
Slot, D.E.:
Slot, D.E.:
Veen, M.H. van der:
Veen, M.H. van der:
Veen, M.H. van der:
Waal, I. van der:
Section Head "Cytokine and Growth Factors Section" MASC/ISSO Mucositis
Study Group.
Founding member International Group for Light in Oncology Barcelona
(iGLOB).
International reviewer Italian Scientific Societies of Oncology and
Radiotherapy (AIOM and AIRO) Consensus Statements about head and neck
supportive care.
Advisory board member Glaxo Smtih Kline (GSK).
Member scientific committee Dutch Society of Endodontology (NVvE).
Country representative European Society of Endodontology (ESE).
Membership secretary and webmaster European Organization for Caries
Research (ORCA).
Member working group to develop new guidelines for Infection Prevention in
dentistry for the NMT Nederlandse Vereniging voor Medische Microbiologie.
September 2013-2014.
Advisory board member Global Dental Hygiene.
Poster jury ADHA Boston USA, 19 June, 2013.
Immediate past president Diagnostic Sciences Group, International
Association for Dental Research (IADR).
Secretary general European Organization for Caries Research (ORCA).
Honorary lecturer University of Liverpool, UK.
Member scientific committee STOMA.
Advisory board member DentalCare.com.
Board member EMEA Oral Health Advisory Council.
Supervisor of an external PhD student
Bloemena, E. Supervisor of external PhD student A.W. Turksma with thesis: "Preclinical studies on
immunotherapeutic approaches for the treatment of solid tumors". VU University Amsterdam, 21-11-2013.
Smeele, L.E. Co-supervisor of external PhD student A.M. Kreeft with thesis: "Functional inoperability of oral
and oropharyngeal cancer". Supervisor: prof.dr.A.J.M. Balm; co-supervisor: prof.dr.I.B. Tan: University of
Amsterdam (200 pag.), 22-03-2013.
Societal impact
Oral infections and oral cancer have a substantial impact on the society. Oral infectious diseases are the most
frequent infections in the western society and have important consequences, both medically and
economically. Head and neck squamous cell carcinomas (HNSCC) and specifically oral squamous cell
carcinomas (OSCC) are the most prevalent forms of head and neck cancer. The general aim of the program is
to understand the normal healthy oral cavity and to understand links with general health, to study oral innate
immunity and susceptibility to caries and periodontal diseases, to study prevention and treatment options for
the oral infectious and inflammatory processes and to study the epidemiology and pathegnesis of oral cancers,
in particular in relation to good/poor oral health. In addition, attention is paid to social and psychological
aspects of dental treatment, such as dental anxiety.
Through education, a new generation of dentists and researchers in the Netherlands, Europe and the world
are trained to implement a radical shift from mechanistically and (invasive) treatment oriented professionals
to 21st century oral physicians focused on diagnosis and prevention of dental and of oral infections and
maintenance of the quality of life. Over the last 5 years it has become increasingly clear that oral infections are
having negative impact on cardiovascular health, diabetic status and quality of life. The researchers in this
theme focus on this aspect.
The members of our priority area have had a relative large number of invitations to give lectures at dental
congresses, and to educate the dental profession on fundamental understanding of oral health. Moreover, we
experienced increased interest from newspapers, magazines and radio programs on the above subjects, in
which we participated. The link oral health - general health is actively communicated by the researchers.
Notably, the Dutch Dental Association has announced this link as their anniversary theme for 2014.
42
Important for the dental profession and the general public, is the substantial number of published and
accessible systematic reviews (and meta-analyses) on the various modes of prevention and oral hygiene
measures. These contribute to clinical protocols for the dental profession and form the basis for evidence
based dentistry.
Ongoing clinical research on oral and head/neck cancer contributes to improved prevention, diagnosis and
treatment of relevant patient groups. New plans are developed to bring together knowledge on oral
microbiomes and salivary innate immune peptides with oral cancer diagnosis and pathophysiology.
The program has strong links with all players in the oral care industry; this not only results in “contract
research”, but also in industrial co-funding of grants (STW) and has led to participation of ACTA in the Top
Institute Food and Nutrition (TIFN), where the theme “Oral Health” has been initiated. In this theme, world
players in the oral care industry, the chewing gum industry, flavour industry, food industry and (oral) care
appliances industry collaborate with the University of Wageningen, TNO and ACTA.
The societal impact of the research is evident from the impact on patient care and public dental health, and
from collaborations with the industry, as is shown by for instance the grants obtained and the external reports.
The societal impact of the clinical research contributes to improved prevention, diagnosis and treatment of
relevant patient groups. The societal impact is evident from the items listed below.
Interactions and collaborations with the industry and other non-university groups
Several collaborations exist with the industry, evident from grants obtained over the years; see the list of
current grants in the paragraph of indicators of esteem above.
Interactions with the general public
Several scientists had interviews with the Dutch general press in journals, radio and television or wrote papers
for the general public. More details are listed below.
Crielaard, W. (2013). Orale bacteriën geven steeds meer geheimen kwijt. Interview & Publication, Dentz, 6.
Dekker, J. den: Branche moet anders gaan denken. DFA Magazine 2013, (26), 3-5.
Diermen, D.E. van. ACTA Richtlijn Tandheelkundige ingrepen bij patiënten die antitrombotica gebruiken, 2013.
Jongh, A. de: Het geheim van het werkgeheugen. Trouw 20 July, 2013, 10.
Jongh, A. de: MedscapeMedical News 27 November, 2013. Eye-Movement Therapy Effective in Dental Phobia.
www.medscape.com/viewarticle/815163
Jongh, A. de: Overigens. Frauderende wetenschappers zijn niet geschikt voor hun vak. De universiteit zou hun
doctorstitel moeten intrekken. Folia Magazine 13 March 2013, (2), 45.
Jongh, A. de: Overigens. Frauderende wetenschappers zijn niet geschikt voor hun vak. De universiteit zou hun
doctorstitel moeten intrekken. Folia Magazine 13 March 2013, (2), 45.
Jongh, A. de: Pilletje tegen angst in de tandartsstoel. Algemeen Dagblad 16 November, 2013, 5.
Jongh, A. de: Studio interview TV Studio Max Live. Thursday 5 December, 2013.
Loos, B.G. Is het gevaarlijk om je tandenborstel te delen? Interviewed, newspaper NRC Next, January 28, 2013.
Loos, B.G. Poets je gezond, interview Algemeen Dagblad (AD), Saturday March 2, 2013, Weekend page 17.
Strijp, A.J.P. van (2013). Zo zorg je voor een stralende lach zonder gaatjes. Interview J/M Ouders.
Veerman, E.C.I. (2013). Interview E-magazine ZonMw. De urgentie van resistentie: Sorteer-enzym herkent
specifieke aminozuurvolgorde; Trojaans paard in strijd tegen S. Aureus. September, 13.
Veerman, E.C.I. (2013). Interview Quest. Speciaal speeksel. April 2013.
Impact of the research on professionals
Patients are referred by their dentists to the various specialized clinics of the clinicians participating in the
program for diagnosis and treatment based on the latest scientific evidence. Several scientists of the program
had interviews in Dutch dental Journals. A total of 95 professional publications were written.
Ekkelboom, D. Drukte! Heel veel tegelijk en alles in één, dát vind ik heel fijn. Jaargang 5, nummer 4, May 2013,
Quality Practice Mondhygiëne, pag 42 – 43.
Jongh, A. de: Extractie van diep gewortelde angst. Dentz 2013, (2), 32-37.
Loos, B.G. Bewustwording van mondgezondheid gaat toenemen, interview Quality Practice (QP)
Tandheelkunde, 8 (6): page 4-6.
Loos, B.G. Bewustwording van mondgezondheid gaat toenemen, interview Quality Practice (QP)
Mondhygiene, 5 (4): page 4-6.
43
Loos, B.G. Een verbeterde lichamelijke conditie door behandeling van parodontitis, Dental Info, June 2013.
http://www.dentalinfo.nl/artikelen/n1676/een-verbeterde-lichamelijke-conditie-door-behandeling-vanparodontitis.html
Louropoulou, A. Interview NMT journal, November 2013.
Slot, D.E. & Weijden, G.A. van der. Wat te doen bij peri-implantits, Dental Info, May 2013. NVM-congres over
nazorg, diagnostiek en reiniging van implantaten. http://www.dentalinfo.nl/artikelen/n2136/wat-te-doenbij-peri-implantitis.html
Organization of congresses and symposia for (health care) professionals
Forouzanfar, T., Schulten, E.A.J.M., Baart, J.A. & Karagozoglu, K.H. (2013). Organizers. Wintersymposium Oral
and Maxillofacial Surgery: Amsterdam, the Netherlands (2013, December 13).
Forouzanfar, T., Schulten, E.A.J.M., Baart, J.A. & Karagozoglu, K.H. (2013). Organizers. NVMKA
voorjaarsvergadering: Amsterdam, the Netherlands (2013, May 31).
Raber-Durlacher, J.E.: Organizer Bijwerkingen als gevolg van de behandeling van hoofd-halskanker. NKI/AVL en
AMC, June 24, 2013.
Rademacher, W.M.H. (2013). Organizer. VMTI symposium 2014: Orale complicaties bij oncologische
behandelingen: De Rode Hoed, Amsterdam, the Netherlands (2013, December 31 - 2013, October 04).
Strijp, A.J.P. van: Co-organizer. ACTA symposium Diagnostic codes in Dentistry: Amsterdam, the Netherlands,
November 03, 2013.
Invited speakers at professional congresses or symposia
Bloemena, E. (2013, June 14). Basale Oncologie. Figi Zeist, the Netherlands, NMT congres.
Bloemena, E. (2013, March 26). Cytology of salivary gland tumors. Den Haag, the Netherlands, NVML
Vakbeurs.
Bloemena, E. (2013, November 05). Kwaliteitscriteria Pathologie in het kader van het BVO
Darmkankerscreening. Den Dolder, the Netherlands, WHT thema dag.
Brand, H.S. (2013, April 18). Accidents can happen. Hilversum, the Netherlands, Afscheidssymposium
professor C. de Baat, Stichting Beeld en Geluid.
Brand, H.S. (2013, April 12). De tandarts in beeld. Amsterdam, the Netherlands, Nederlands Filmmuseum.
Crielaard, W. (2013, September 27). The future of microbiology. Noordwijk, the Netherlands, Lustrum
Parodontologie.
Diermen, D.E. van (2013, November 18). Antistolling. Nieuwegein, the Netherlands, Webinar via NMT:
http://www.tandartsennet.nl/richtlijnen/antistolling.html.
Diermen, D.E. van (2013, November 09). Antistolling en medicatie in het algemeen. Den Haag, the
Netherlands, Najaarscongres Nederlandse Vereniging voor Mondhygiëne.
Diermen, D.E. van (2013, November 07). Grensverleggend beleid bij antitrombotica: enquête onder
Nederlandse kaakchirurgen. The Netherlands, NMKA najaarscongres.
Hennequin-Hoenderdos, N.L. (2013, March 26). Uitvoering van klinisch wetenschappelijk onderzoek in de
tandheelkunde. Nieuwegein, the Netherlands, NVM vakgroep Onderzoek.
Jager, D.H.J. (2013, November 21). Comfortable solutions in times of demographic changes. Munich, Germany,
3M ESPE Espertise™ symposium.
Jager, D.H.J. (2013, September 12). Tanderosie. Maastricht, the Netherlands, Tandheelkunde up to date 2013.
Jongh, A. de (2013, August 27). Psychische problemen met consequenties voor de praktijk. Amsterdam, the
Netherlands, VMTI congres "Tussen de Oren".
Jongh, A. de (2013, November 11). Traumabehandeling: Waarom lang als het kort kan? Amsterdam, the
Netherlands, De Ultieme Update, stabilisatie.
Karagozoglu, K.H. (2013, September 05). Management of oral cancer. Amsterdam, the Netherlands, European
Meeting on Oral Diseases.
Krom, B.P. (2013, October 08). Microbiële biofilms in chronische wonden, van ecologie tot behandeling.
Eindhoven, the Netherlands, Wondsymposium.
Krom, B.P. (2013, January 30). Schimmels in de mond bij geriatrische patiënten. Amsterdam, the Netherlands,
Studiegroep voor Geriatrische Tandheelkunde.
Laine, M.L. (2013, November 14). Halitose. Middelburg, the Netherlands, West Brabantse Tandarsten
Vereniging.
44
Laine, M.L. (2013, September 24). Oorzaak, herkenning en behandelmogelijkheden van halitose. Alkmaar, the
Netherlands, Stichting PAOT Noord-Holland Noord.
Laine, M.L. & Slot, D.E. (2013, June 05). Preventie loont, een gezonde gingiva en een frisse adem. Amsterdam,
the Netherlands, GABAWorks.
Laine, M.L. & Slot, D.E. (2013, June 04). Preventie loont, een gezonde gingiva en een frisse adem. Den Bosch,
the Netherlands, GABAWorks.
Laine, M.L. & Slot, D.E. (2013, June 12). Preventie loont, een gezonde gingiva en een frisse adem. Zwolle, the
Netherlands, GABAWorks.
Loos, B.G. (2013, April 12). Behandeling van parodontitis verbetert de algemene gezondheid. the Netherlands,
Springmeeting Dutch Society of Dental Hygiene (NVM).
Loos, B.G. (2013, November 14). Parodontitis bij 55+. Rotterdam, the Netherlands, De Tand in al zijn facetten,
National scientific congress, WTA, NVT, NVvE, NVVRT.
Loos, B.G. (2013, September 11). Periodontitis, general health and saliva diagnostics. Eindhoven, the
Netherlands, Philips Oral Health care workshop Opportunities in Saliva Diagnostics Philips Laboratories,
High Tech Campus.
Louropoulou, A. (2013, January 22). Hoe tandheelkundige implantaten te reinigen. Eindhoven, the
Netherlands, Oral B up to date events.
Louropoulou, A. (2013, November 22). De reiniging van implantaat-gedragen constructies. Utrecht, the
Netherlands, NvVP najaarscongres parallelprogramma.
Louropoulou, A. (2013, February 07). Hoe tandheelkundige implantaten te reinigen. Apeldoorn, the
Louropoulou, A. (2013, May 16). Hoe tandheelkundige implantaten te reinigen. Heerenveen, the Netherlands,
Oral B up to date events.
Louropoulou, A. (2013, October 03). Hoe tandheelkundige implantaten te reinigen. Heerenveen, the
Rozema, F.R. (2013, June 06). Capita Selecta 1, Tandheelkunde vs. Geneeskunde: De mond openbaart.
Amsterdam, the Netherlands, Medisch Tandheelkundige Interactie VMTI.
Rozema, F.R. (2013, October 03). Quality control integrated in EHR? Amsterdam, the Netherlands, Symposium
Diagnostische codes voor de Mondzorg, ACTA.
Slot, D.E. (2013, January 22). Hoe tandheelkundige implantaten te reinigen. Eindhoven, the Netherlands, Oral
B up to date events.
Slot, D.E. (2013, March 06). 1. Hoe tandheelkundige implantaten te reinigen. 2. Hoe kan een patiënt zijn
implantaat het beste reinigen? Amsterdam, the Netherlands, Oral B up to date events.
Slot, D.E. (2013, March 07). 1. Hoe tandheelkundige implantaten te reinigen. 2. Hoe kan een patiënt zijn
implantaat het beste reinigen? Maarssen, the Netherlands, Oral B up to date events.
Slot, D.E. (2013, February 07). Hoe kan een patiënt zijn implantaat het beste reinigen? Apeldoorn, the
Slot, D.E. (2013, May 16). Hoe kan een patiënt zijn implantaat het beste reinigen? Heerenveen, the
Slot, D.E. (2013, October 03). Hoe kan een patiënt zijn implantaat het beste reinigen? Heerenveen, the
Waal, I. van der (2013, November 01). De mond als spiegel van de gezondheid. Rotterdam, the Netherlands,
Afscheidssymposium A.G. Dumans.
Waal, I. van der (2013, November 13). Maligne en premaligne afwijkingen. Den Haag, the Netherlands,
Openingssymposium afdeling MKA Bronovo ziekenhuis.
Waal, I. van der (2013, March 22). Mondkanker in de tandartspraktijk: dat mag je niet missen. Hoe kan
mondkanker eerder worden opgespoord? Mondkanker in de tandartspraktijk: dat mag je niet missen Hoe
kan mondkanker eerder worden opgespoord? Rotterdam, the Netherlands, Congress Mondkanker dat mag
je niet missen.
Waal, I. van der (2013, March 23). Orale leukoplakie; diagnostiek en behandeling. Amersfoort, the
Netherlands, 2e Dermatologen-in-opleidingdagen.
Waal, I. van der (2013, June 14). Ulceraties van het mondslijmvlies; een uitdaging voor de tandarts. Klinischröntgenologische diaquiz; bespreking van 10 casussen. Zeist, the Netherlands, NMT Jaarcongres 2013.
Weijden, G.A. van der (2013, June 21). Nazorg bij implantaten. Ermelo, the Netherlands, Camlog congress.
45
Other professional functions:
Bloemena, E.:
Bloemena, E.:
Bloemena, E.:
Bloemena, E.:
Bloemena, E.:
Bloemena, E.:
Danser, M.M.:
Diermen, D.E. van:
Diermen, D.E. van:
Diermen, D.E. van:
Gorter, R. C.:
Gorter, R. C.:
Laine, M.L.:
Loveren, C. van:
Loveren, C. van:
Loveren, C. van:
Rosema, N.A.M.:
Rozema, F.R.:
Rozema, F.R.:
Rozema, F.R.:
Slot, D.E.:
Slot, D.E.:
Slot, D.E.:
Strijp, A.J.P. van:
Weijden, G.A. van der & Kroon, T.L.J.M.:
Weijden, G.A. van der & Slot, D.E.:
Weijden, G.A. van der & Slot, D.E.:
Weijden, G.A. van der & Winkel, E.G.:
46
Member committee Beroepsuitoefening en Kwaliteit NVVP.
Member committee Kwaliteit en Capaciteit Bevolkingsonderzoek
Darmkanker.
Member committee Kwaliteitseisen Pathologie Bevolkingsonderzoek Darmkanker.
Member committee Richtlijn Hepatocellulair Carcinoom.
Member committee Richtlijn Hoofd Hals Kanker.
Chair Wetenschappelijke Raad PALGRA.
Chairman Dutch Society for Periodontology
Member
Education
committee
(Vereniging
Medisch
Tandheelkundige Interactie (VMTI).
Secretary Nederlands Taalkundig Genootschap, Nieuwegein.
Member Working group 2 Kamer Mondzorg.
Kamer Mondzorg – werkgroep 2. Richtlijnen Tandheelkunde. NMT
(2013).
Member Program Review Board of the Educational Research
Program Department of Education Culture and Science.
Member Epidemiology Educational Programs Audit Committee
Netherlands Epidemiology Society.
Advisory member Rhinosinusitis Practice Guide Panel. American
Association of Otolaryngology and Head and Neck Surgery.
External reviewer brochure “Slechte adem”, Ivoren Kruis.
Member working group 2 Foundation Kennis Instituut Mondzorg.
Member Guidelines Committee Richtlijn Mondzorg voor jeugdigen.
Chairman scientific advisory board Preventive Dentistry and Oral
Diseases, Ivoren Kruis.
Member Accreditatie-Commissie KwaliteitsRegister mondhygiënisten (KRM).
Member COK.
Chair Consilium Chirurgicum Oris.
Councillor IAOMS.
Member Commissie Richtlijn parodontale behandeling in de
algemene praktijk, Nederlandse Vereniging voor Parodontologie
(NVvP).
Member Congres Commissie Nederlandse Vereniging voor
Parodontologie (NVvP).
Member Lustrum Commissie Nederlandse Vereniging voor
Advisor Guidelines Committee Mondzorg voor jeugdigen.
Member Commissie richtlijn mankrachtplanning Nederlandse
Vereniging voor Parodontologie (NVvP).
Member Commissie Richtlijn parodontale behandeling in de
algemene praktijk, Nederlandse Vereniging voor Parodontologie
(NVvP).
Member Commissie richtlijn Peri-Implantitis NVOI/NVvP.
Member Redactieraad allesoverhetgebit.nl.
Board member Dutch Society for Periodontology.
Members redactie Folder roken en parodontitis Nederlandse
Members working group Paro Algemene praktijk.
Members redactie Folder mondspoelmiddelen Nederlandse
Members redactie Folder halitose Nederlandse Vereniging voor
Courses organized for dental and medical professionals
Scientists of the program participated in courses in the Netherlands for dentists and oral hygienists. More than
16 courses were given in the Netherlands for dentists, medical specialists and oral hygienists by:
Brand, H.S. & Diermen, D.E. van. Organization cursus Acute medische situaties in de tandartspraktijk. 31 May
2013. ACTA PAOT-cursus, Amsterdam.
Deng, D. (2013, October 28 - November 8). Training course on dental education. This course is organized for 18
teachers from Shanghai Jiao Tong University College of Stomatology.
Diermen, D.E. van. Moderator bij Quality Practice voor mondhygiënisten: Medische situaties in de
Mondhygienepraktijk, 13 April 2013 (200 deelnemers)
Diermen, D.E. van. Cursus "Alles over de medische ananmese" voor Mondhygiënisten via DCM, 14 June 2013
(12 deelnemers)
Diermen, D.E. van. PAOT cursus Acute Medische situaties in de tandartspraktijk" op vrijdag 31 mei 2013 (16
deelnemers)
Diermen, D.E. van. Moderator bij najaarscongres NVM: "The circle of life" op zaterdag 9 november 2013 in
Den Haag (500 deelnemers)
Gorter, R.C. Organizer. ACTA QP: MHG2 – Gedragsbeïnvloeding: kan ik het ook op een andere manier? (9-22013).
Strijp, A.J.P. van & Roeters, J.F.M. (11-10-2013). ADE course: Risicomanagement: Cariës en weefselverlies.
Ministry of Defense.
Waal, I. van der. Mondpathologie. Een nascholingscursus voor de KNO-artsen en dermatologen" Amsterdam,
1 February 2013.
Wesselink, P.R. (2013). Leergang endodontologie 9 x 1,5 dag per jaar en twee eendaagse nascholingscursussen
voor ACTA QP.
Lectures given during courses for dental and medical professionals in the Netherlands
A large number of lectures were given during courses for dentists, medical specialists and oral hygienists in the
Netherlands.
Aartman, I.H.A. April 20 and May 18 2013, ACTA Quality Practice, “Hoe waarschijnlijk is mijn diagnose?”
Aartman, I.H.A. November-December 2013, Statistics for Periodontology MSc.
Bizzarro, S. Parodontale chirurgie bij de behandeling van parodontitis, Paroprotocol on road, ACTA Dental
Education, Apeldoorn, the Netherlands, June 7, 2013.
Bizzarro, S. Parodontale chirurgie bij de behandeling van parodontitis, Paroprotocol on road, ACTA Dental
Education, Breda, the Netherlands, October 4, 2013.
Bloemena, E. Wat doet een patholoog? Opleiding tot oncologisch verpleegkundige. Amstel academie, VU,
Amsterdam, the Netherlands 12-11-2013.
Bloemena, E. Histology of head and neck squamous cell carcinoma, OOA Course, VUmc, Amsterdam, the
Netherlands. 31-1-2013
Bloemena, E. Cytology of salivary gland tumors, AIOS course, AMC, Amsterdam, the Netherlands. 29-1-2013
Bloemena, E. Wat is kanker? PAOT cursus voor tandartsen, ACTA, Amsterdam, the Netherlands. 5-4-2013.
Brand, H.S. De tandarts in beeld. Nederlands Filmmuseum, Amsterdam.
Brand, H.S. Acute medische situaties en reanimatie in de mondhygiënepraktijk. ACTA-QP, Amsterdam.
Brand, H.S. Accidents can happen. Afscheidsymposium professor C. de Baat. Stichting Beeld en Geluid,
Hilversum.
Brand, H.S. Zuur voor het glazuur. Voordracht voor tandartsassistenten. Egmond aan Zee, 6 september 2013.
Brand, H.S. Medisch Tandheelkundige Interactie. Stichting PAOT-Noord Nederland. Groningen, 10 October
2013.
Danser, M.M. ACTA QP dag, “Röntgendiagnostiek”, April 20 and May 18, 2013.
Danser, M.M. ACTA QP dag, “Micro-organism and plaque”, May 2, 2013.
Danser, M.M. Parodontale nazorg en antibiotica gebruik bij paro-patiënten”, Paroprotocol on road, ACTA
Dental Education, Apeldoorn, The Netherlands, June 7, 2013.
Danser, M.M. Moderator ACTA-QP + lecture “AB + CHX, wat is de meerwaarde”, Amsterdam, June 8, 2013.
Danser, M.M. ACTA QP dag, “Gebruik van Antibiotica bij parodontitis”, June 15 and 22, 2013.
Danser, M.M. Parodontale nazorg en antibiotica gebruik bij paro-patiënten, Paroprotocol on road, ACTA
Dental Education, Breda, the Netherlands, October 4, 2013.
47
Diermen, D.E. van. 4 January2013: voordracht klinische stafdagen ACTA: MTI, handelen in noodsituaties.
Diermen, D.E. van. 9 January 2013: college Medische Anamnese voor 1e jaars thk studenten en staf.
Diermen, D.E. van. 4 January 2013: voordracht Klinisch Forum ACTA antibiotica bij kunstgewrichten samen
met Rachid Saouti VUmc.
Diermen, D.E. van. 13 April 2013: Antibioitica profylaxe, wanneer wel en wanneer niet? QP voor
mondhygienisten.
Diermen, D.E. van. 13 April 2013: Antitrombotica in de mondzorg: wel of niet laten stoppen met
bloedverdunners? QP voor mondhygienisten.
Diermen, D.E. van. 4 May 2013: “Prophylactic medication Antithrombotic treatment & Prophylactic
medication: Antibiotic treatment” voor Russische tandartsen en mondhygienisten. Quality Practice.
Diermen, D.E. van. 31 May 2013: Voordracht "Bewustzijnsstoornissen" en "Medische Noodkoffer" en
"Lotusslachtoffers" op PAOT cursus Acute Medische situaties in de tandartspraktijk".
Diermen, D.E. van. 4 September 2013: "De medische aspecten van lachgas", voordracht bij ACTA
lachgascursus.
Diermen, D.E. van. 24 September 2013: "Acute medische situaties". Compact Clinic bij Paropraktijk
Amsterdam.
Diermen, D.E. van. 27 November 2013: "De Medische Anamnese" en "Anticoagulantia en AB-profylaxe".
Masterclass Implantologie ACTA, Amsterdam.
Forouzanfar, T. Oral cancer and the role of the dentist. QP Dental Education, Amsterdam 26 January en 2
February 2013.
Huffels, R.A.M. Effecten van de initiële behandeling, Paroprotocol on road, ACTA Dental Education, Breda, the
Netherlands, October 4, 2013.
Jong, T.M.H. de. Effecten van de initiele behandeling, Paroprotocol on road, ACTA Dental Education,
Apeldoorn, the Netherlands, June 7, 2013.
Jong, T.M.H. de. Workshop vitamine C & parodontitis, Quality Practice ACTA, Amsterdam, June 8, 2013.
Josselin de Jong, E. de & Veen, M.H. van der. QLF-camera: hulpje in preventie. Ivoren Kruis Preventie
Academie. (1x)
Laine, M.L. Hoe om te gaan met slechte adem?, Paroprotocol on road, ACTA Dental Education, Apeldoorn, the
Netherlands, June 7, 2013.
Laine, M.L. Hoe om te gaan met slechte adem? Paroprotocol on road, ACTA Dental Education, Breda, the
Laine, M.L. 2x workshop ACTA QP dag, “Hoe bepaalt u ademgeur van uw patiënten?”, Amsterdam. June 15
and 22, 2013.
Loos, B.G. Masterclass to medical PhD students (preceeding Ruysch Lecture), Academic Medical Center (AMC),
University of Amsterdam, the Netherlands, October 15, 2013.
Loos, B.G. Nieuwe inzichten in de etiologie en epidemiologie van parodontitis, Paroprotocol on road, ACTA
Loos, B.G. Nieuwe inzichten in de etiologie en epidemiologie van parodontitis, Paroprotocol on road, ACTA
Dental Education, Apeldoorn, the Netherlands, June 7, 2013.
Loos, B.G. Mondgezondheid en de relatie met algemene gezondheid, Philips Event, Amsterdam, May 31, 2013.
Loos, B.G. Nieuwe inzichten in de etiologie en epidemiologie van parodontitis & De relatie tussen parodontitis
en hart- en vaatziekten, Ordental, Rotterdam, May 27, 2013.
Loos, B.G. Parodontologie – Implantaat verlies – Peri-implantitis Masterclass Implantology, ACTA Dental
Education, May 22, 2013.
Loos, B.G. Post-adolescente parodontitis en ons dilemma wel/niet systemische antibiotica, Department of
Periodontology Verwijzersavond, April 10, 2013.
Loveren, C. van. Verschillende preventievoordrachten bij Ivoren Kruis Preventie Academie.
Paraskevas, S. Parodontale herbeoordeling, Paroprotocol on road, ACTA Dental Education, Apeldoorn, the
Paraskevas, S. Parodontale herbeoordeling, Paroprotocol on road, ACTA Dental Education, Breda, the
Rosema, N.A.M. Update Parodontologie workshop, Quality Practice ACTA, Amsterdam, 8 June 2013.
Rozema, F.R. Patiënten en hun pillen. Antibiotica en Pijnstillers. Themaproject 2013. The big four NVT, Den
Haag; 17 April 2013
Rozema, F.R. Medisch Tandheelkundige Interactie. Stafavond. ACTA. 26-06-2013.
Slot, D.E. “Do lasers/photodynamic therapy have a role in Non surgical periodontal treatment?” ACTA QP, 8
June 2013.
48
Strijp, A.J.P. van. ACTA course Dentistry for non-dentists. Cariology, epidemiology and treatment. (28-2-2013).
Strijp, A.J.P. van. QP Tandheelkunde Diagnostiek. Workshop Cariës diagnostiek, de sonde voorbij (20-4-2013
and 18-5-2013).
Strijp, A.J.P. van. ACTA Klinische forum (5-9-2013 and 16-9-2013).
Strijp, A.J.P. van. QP Assistenten Symposium. Moderne cariësbehandeling: Motiveren in plaats van excaveren
(4-10-2013).
Strijp, A.J.P. van. QP Tandheelkunde Themadag Modern Cariësmanagement in restauratief perspectief.
Moderne inzichten in de Cariologie (30-11-2013 and 7-12-2013).
Teeuw, W.J. Parodontale screening in de algemene praktijk, Paroprotocol on road, ACTA Dental Education,
Apeldoorn, the Netherlands, June 7, 2013.
Teeuw, W.J. Parodontale screening in de algemene praktijk, Paroprotocol on road, ACTA Dental Education,
Breda, the Netherlands, October 4, 2013.
Velden, U. van der. Voeding: de verwaarloosde factor in de Parodontologie, Paroprotocol on road, ACTA
Dental Education, Apeldoorn, the Netherlands, June 7, 2013.
Velden, U. van der. Voeding: de verwaarloosde factor in de Parodontologie, Paroprotocol on road, ACTA
Waal I. van der. Mondziekten. Een nascholingscursus voor mondhygiënisten. Organisatie: NVM. Breukelen; 15
March 2013.
Waal I. van der. Oncologie voor de tandarts.. Amsterdam (ACTA). 5 April 2013.
Waal I. van der. Oncologie voor de mondhygiënist. Organisatie: NVM. Almere.4 October 2013.
Waal I. van der. Diseases of the oral mucosa. Dental education ACTA, Dental hygienists from Rusland. 3
May2013.
Weijden, G.A. van der. Workshop Air polisher, Utrecht, the Netherlands, February 13.
Weijden, G.A. van der. Workshop Hechten, Amsterdam, the Netherlands. March 7.
Weijden, G.A. van der. Seminar Paro-Restauratief, Amsterdam, the Netherlands, March 7.
Weijden, G.A. van der. Tandhalsgevoeligheid, Den Bosch, the Netherlands, March 11.
Weijden, G.A. van der. Tandhalsgevoeligheid, Amsterdam, the Netherlands, March 12.
Weijden, G.A. van der. Tandhalsgevoeligheid, Zwolle, the Netherlands, March 13.
Weijden, G.A. van der. Workshop Air polisher, Drachten, the Netherlands, February 13.
Weijden, G.A. van der. Seminar Periodontal maintenance, Amsterdam, the Netherlands, May 23.
Weijden, G.A. van der. Workshop air polisher, Amsterdam, the Netherlands, May 23.
Weijden, G.A. van der. Seminar mouthrinses and interdental cleaning, Amsterdam, the Netherlands, May 30.
Weijden, G.A. van der. Moderator ACTA-QP, Amsterdam, the Netherlands, June 15.
Weijden, G.A. van der. Workshop air polisher, Utrecht, the Netherlands, September 2.
Weijden, G.A. van der. Workshop air polisher, Utrecht, the Netherlands, October 23.
Weijden, G.A. van der. Tandhalsgevoeligheid, Regiobijeenkomst NVM, Utrecht, the Netherlands, October 31.
Weijden, G.A. van der. Alles over Mondhygiëne, Compact Clinic KPA, Amsterdam, the Netherlands, November
12.
Weijden, G.A. van der. Nazorg bij implantaten, Antwerpen, Belgium, November 14.
Weijden, G.A. van der. Mondhygiëne, Ivoren Kruis symposium, Amsterdam, the Netherlands, November 16.
Weijden, G.A. van der. Nazorg bij implantaten, Het vervolg-NVOI, Putten, the Netherlands, December 13.
Wesselink, P.R. Twee klinische avonden voor tandheelkundige professionals.
Wesselink, P.R. Tooth injury (Tandletsel). September 28 and October 11 Moderator and speaker ACTA QP Acta
dental education BV.
Zerbo, I.R. Implanteren bij de paro-patiënt, Paroprotocol on road, ACTA Dental Education, Apeldoorn, the
Zerbo, I.R. Implanteren bij de paro-patiënt, Paroprotocol on road, ACTA Dental Education, Breda, the
Collaborations
-
Ben Gurion University of the Negev, Beer Sheva, Israel, Dr. M. Meijler.
Brandwondencentrum Beverwijk, Dr. B. Boekema, Brandwonden project.
Cairo University, Egypt, Oral Medicine and Periodontology Department, Faculty of Dentistry, Clinic for
Conservative Dentistry and Periodontology, Uniklinikum Schleswig-Holstein-Campus, Kiel, Germany, Karim
M. Fawzy El-Sayed
49
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50
Common Wealth University, Virginia, Prof.dr. H.A. Schenkein
Dr. Y. Iijima. University of Nagasaki, Japan.
Erasmus medisch Centrum, Dr. M. van Zelm
ERC starting grant. UMCG Groningen, Brandwonden project.
Indiana University-Purdue University, Fort Wayne, IN, USA, Health Science Research Center, Mark Putt
Interleukin Genetics, USA: Prof. dr. K. Kornman
Isala Klinieken Zwolle, Algemene Chirurgie, Dr. J. Oskam.
Prof.Dr. W.H. van Palenstein Helderman, Utrecht
Tigran, Malmö, Sweden, U. Lundgren
TNO, Zeist, Dr. E. Tsivtsivadze
UMCG Groningen, Dr. L.U. Lahoda
Uniklinikum Schleswig-Holstein-Campus, Kiel, Germany, Clinic for Conservative Dentistry and
Periodontology, Christof Doerfer
Universiteit van Amsterdam, AMC, Dept. of Clinical Chemistry
Universiteit van Groningen, Dept. of Periodontology
University Federico II, Naples, Italy. Department of Periodontology, Andrea Blasi
University of Bandung, Indonesia, Amaliya
University of Bonn, Dept. of Periodontology, Prof.dr. S. Jepsen
University of Kiel, Germany, Dept. of Gastro‐Enterology, Prof.dr. S. Schreiber
University of Kiel, Germany, Institute for Clinical Molecular Biology, Dr. A. Scheafer
University of Kristianstad, Sweden, Prof. dr. S. Renvert
University of Madrid, Spain, Prof. dr. M. Sanz
University of Malaya, Malaysia, Faculty of Dentistry, Dr. Rathna Devi Vaithilingam
University of Maryland Dental School, Baltimore, USA, Dr. M.A. Jabra-Rizk.
University of Milan, Italy, Unit of Periodontology, Giulio Rasperini
University of Missouri-Kansas City, USA, Dept. of Periodontics, School of Dentistry, Charles Cobb
University of Patras, Greece, Prof.dr. T. Bountis
University of Rome, Italy, Prof. dr. Pilloni
AMC: Dept of microscopy. Dr J. Stap, Amsterdam
Birkhoven zorggoed. Vakgroep medische dienst. Dr. G.J. van der Putten. Amersfoort
Centre for Integrative Bioinformatics (IBIVU), VU Amsterdam, Prof. J. Heringa, Dr. S. Abeln.
Department of Farm Animal Health, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the
Netherlands. Dr. Gerrit Koop.
Department of Oral Medicine, Charlotte, NC, USA. Mike Brennan and Peter Lockhart.
Dr. Alex Mira, Center for Advanced Research in Public Health, Valencia, Spain.
Dr. Wilfred Röling, Molecular Cell Physiology, FALW, VU.
Erasmus MC, Department of Medical Microbiology and Infectious Diseases, Rotterdam, the Netherlands.
Mw. W.E. Kaman-van Zanten, dr. J.P. Hays, dr. Willem van Wamel
Fong Moy MD, Prof. Awang Bulgiba, MSc PhD, Medical School, University of Malaysia, Kuala Lumpur,
Malaysia
Hebrew University-Hadassh. Dr. Davidovich, Jerusalem, Israel
Khon Kaen University, Dept. Of Oral Diagnosis. Dr. S. Taweechaisupapong, Khon Kaen, Thailand).
Kindertandheelkundepraktijk Bambodino. Dr. D.L. Gambon, Rotterdam
Max Planck Institute for Chemical Ecology, Department of Bioorganic Chemistry, Jena, Germany. Prof Dr
Axel Mithoefer,
Max Planck Institute for Chemical Ecology, Department of Bioorganic Chemistry, Prof. dr. Axel Mithoefer,
Jena, Germany
Medical School, Prof. van Laar, Newcastle upon Tyne, U.K.
Medisch Centrum Leeuwarden. Dr. De Visscher, Leeuwarden
Nederlands Speekselcentrum. Dr. C.P. Bots, Hilversum
Paul Glasziou, Centre for Research in Evidence-Based Medicine, Faculty of Health Sciences and Medicine,
Bond University, Queensland, Australia, and Centre for Evidence-Based Medicine & Department of Primary
Care, Oxford University, Oxford UK
Peking University School of Stomatology. Prof. Hong Hua, Beijing, China
Prof. Helen Worthington, PhD; Paul Brocklehurst PhD; Prof Iain Tickle, PhD; School of Dentistry, The
University of Manchester, Manchester, UK
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Regional Center for Biomedical Research, Albacete Science & Technology Park, University of Castilla-- La
Mancha, Albacete, Spanje. Dr. P.W.J. de Groot.
S. Widyahening-Aribowo MD, & Prof Sudigdo Sastroasmoro, MD PhD, Medical School, Universtiy of
Indonesia, Jakarta, Indonesia
Sanquin: Department of Immunopathology: Dr D. Wouters, Amsterdam
Universitair Medisch Centrum Utrecht. Dr. Dijkema, Utrecht
University of Calgary, Dept. of Biological Sciences. Prof. dr. H.J. Vogel, Calgary, Canada.
University of California Los Angeles, School of Dentistry. Dr. D.T. Wong. Los Angeles, USA
University of Chiang Mai, Dept of Odontology and Oral Pathology. Dr. S. Krisanaprakornkit), Chiang Mai,
Thailand
University of Chile, Faculty of Medicine Institute of Biomedical Science, María-Julieta González Burgos,
Santiago, Chile
University of Oporto, Dept. of Chemistry. Dr. M. Bastos, Porto, Portugal,).
University of Sinaloe, Faculty of Medicine, Hospital Pediatrico de Sinaloa. Dr. N. León Sicairos, Sinaloa,
Mexico
Utrecht University, Department of Infectious Diseases and Immunology, Utrecht, the Netherlands. Prof. dr.
H.P. Haagsman
VUMC, Molecular Cell Biology and Immunology: Dr. M. Boks, Amsterdam
VUMC, Dept. of Dermatology. Prof. dr. S. Gibbs, Amsterdam
Current PhD projects
Arikan, M. Supervisor: prof.dr. W. Crielaard; co-supervisor: dr. E. Zaura, start: December 2012.
Beerens, MW. Aspects in the prevention of caries in patients undergoing orthodontic treatment with multibracket fixed appliances. Supervisor: prof.dr. J.M. ten Cate; co-supervisor: dr.ir. M.H. van der Veen, start:
study in 2007, decision applying for PhD thesis in 2013.
Benzian, H. The neglected state of global oral health- a roadmap for effective change. Supervisors: prof. dr.
G.A. van der Weijden & prof.dr. W.H. van Palenstein Helderman, start: 2010.
Bizzarro, S. The local and systemic effects of periodontal therapy modalities on risk biomarkers of
cardiovascular disease. Supervisor prof.dr. B.G. Loos, start: June 2009.
Boink, MA. Histatin peptides for treatment of chronic wounds. Supervisors: prof.dr. E.C.I. Veerman and
prof.dr. S Gibbs; co-supervisor: dr J.G.M. Bolscher, start: November 2010.
Bont, PAJM de. Treatment of trauma in psychosis (TTIP)2. Supervisors: prof.dr. A. de Jongh & prof.dr. A. van
Minnen, start: 2011.
Broers, DLM. Experienced-based dentistry in individuals with physical and/or mental limitations. Supervisors:
prof.dr. A. de Jongh & prof.dr. A.J. Feilzer, start: 2012.
Brouns, EREA. Oral Leukoplakia; diagnosis and treatment. Supervisors: prof.dr. I. van der Waal & prof.dr. E.
Bloemena, start: 2010.
Cukkemane, N. Design of protective coatings against dental erosion for application in oral care products.
Supervisors: prof.dr. E.C.I.Veerman; co-supervisors: dr. F.J. Bikker & dr. H.S. Brand, start: December 2009.
Dautovic, E. Effectiveness of EMDR among adults with PTSD and an intellectual disability. Supervisors: prof.dr.
A. de Jongh & prof.dr. F. Oort.
Dekker, H. Peri-implantitis, implant loss and osteoradionecrosis in oral cancer patients. Supervisors: prof.dr.
E.A.J.M. Schulten, prof.dr. C.M. ten Bruggenkate & prof.dr. E. Bloemena; co-supervisor: dr. N. Bravenboer,
start: 2010.
Diermen, DE van. Development of guidelines. Supervisors: prof.dr. I. van der Waal & prof.dr. J. Hoogstraten.
Start January 2007.
Donders, HCM. The effects of periodontal therapy on systemic health of patients with cardiovascular disease.
Supervisors: prof.dr. J. de Lange & prof.dr. B.G. Loos, start: January 2011.
Dubois, L. Predictablility of orbital reconstruction. Supervisor: prof.dr. A.G. Becking, start: September 2011.
Duijster, D. The prevention of early childhood caries of children at high risk. Supervisors: prof.dr. C. van
Loveren & prof.dr. G.H.W. Verrips, start: September 2010.
Dijk, IA van. How histatins enhances wound closure: structural and cellular aspects. Supervisor: prof.dr. E.C.I.
Veerman; co-supervisor: dr. J.G.M. Bolscher, start: February 2011.
Elfrink, MEC. Deciduous molar hypomineralisation, its nature and nurture. Supervisors: prof.dr. J.M. ten Cate
& prof.dr. H.A. Moll; co-supervisor: dr. J.S.J. Veerkamp, start: 2008.
51
Exterkate, RAM. Biofilm model for studying antimicrobial agents. Supervisors: prof.dr. J.M. ten Cate & prof.dr.
W.Crielaard, start: 2007.
Fernandez y Mostajo, M. Novel methods for preventing and treating polymicrobial biofilm infections in the
oral cavity. Supervisors: prof.dr. W. Crielaard, prof.dr. G.A. van der Weijden & prof.dr. W. Beertsen; cosupervisor: dr. E. Zaura, start: June 2011.
Geurs, NC. Socket preservation after extraction for implant dentistry. Supervisors: prof.dr. B.G. Loos & prof.dr.
U. van der Velden, start: 2010.
Groot, M de. Skull growth in oncological treatments in childhood. Supervisor: prof.dr. L.E. Smeele, start:
January 2013.
Gunput, STG. The effect of saliva on the complement system. Supervisor: prof.dr. E.C.I. Veerman; cosupervisor: dr. A.J.M. Ligtenberg, start: January 2012.
Hansenova Manaskova, S. Sortase as target for antimicrobial peptides. Supervisor: prof.dr. E.C.I. Veerman; cosupervisor: dr. F.J. Bikker, start: November 2010.
Harkel ten, B. Comparison foreign body giant cells and osteoclasts. Supervisor: prof.dr. V. Everts; cosupervisor: dr.ir. T.J. de Vries, start: December 2011.
Haverman, T.M. Oral Mucositis. Supervisors: prof.dr. F.R Rozema, prof.dr. J. de Lange, dr. J.E. Raber-Durlacher.
Start January 2013.
Helmers, R. Hyperbaric oxygen therapy and micro vascularisation. Supervisor: prof.dr. J. de Lange, start:
September 2011.
Hertog, D. Treatment of ameloblastomas. Supervisor: prof.dr. I. van der Waal, start: September 2009.
Houtem, CMMH van. ADRA2B polymorphism as a putative biomarker for the acquisition of anxiety based on
inadequate storage of emotional memories. Supervisors: prof.dr. A de Jongh & prof.dr. W. Crielaard, start:
September 2009.
Imangaliyev, S. Novel strategies to promote oral health. Supervisor: prof.dr. W. Crielaard; co-supervisor: dr.
B.J.F. Keijser, start: September 2012.
Irshad, M. Host-pathogen interactions in peri-implant infections. Supervisor: prof.dr. W. Crielaard; cosupervisors: dr. M.L. Laine & dr. W.A. van der Reijden, start: January 2007. Graduation: December 19, 2013.
Janus, MM. Microbial interactions in oral biofilms. Supervisor: prof.dr. W. Crielaard; co-supervisor: dr. B.P.
Krom, start: June 2012.
Jiang, LM. Insights into passive ultrasonic irrigation. Supervisor: prof.dr. P.R. Wesselink; co-supervisors: dr.
L.W.M. van der Sluis & dr. A.M. Versluis & dr. D.M. Deng, start: October 2007.
Jong, BG. de Local and systemic antibody responses for maintaining gingival health. Supervisors: prof.dr. W.
Crielaard & prof.dr. B.G. Loos; co-supervisor: dr. M.C. van Zelm, start: April 2012.
Jong-Lenters, M de. Family, oral health, weight and growth. Supervisor: prof.dr. G.H.W. Verrips; co-supervisor
prof.dr. J. Hoogstraten, start: November 2010.
Kaaij, NCW van der. Efficacy of fluoride rinse in the prevention of caries in patients undergoing orthodontic
treatment with multi-bracket fixed appliances. Supervisor: prof.dr. J.M. ten Cate; co-supervisor: dr.ir. M.H.
van der Veen, start: study in 2009, decision applying for PhD thesis in 2013.
Kaiwar, A. Supervisor: prof.dr. P.R. Wesselink; co-supervisor: dr. H. Shemesh, start: 2012.
Karagozoglu, KH. Classification and treatment of osteoradionecrosis. Supervisors: dr. T. Forouzanfar and
prof.dr. I. van der Waal. Start: 2012.
Koopman, JE. Preventie van cariës in het melkgebit bij kinderen at risk. Supervisors: prof.dr. W. Crielaard &
prof.dr. C. Van Loveren; co-supervisors: dr. B.J.F. Keijser & dr. E. Zaura, start: April 2012.
Kraneveld, EA. Understanding Candida proliferation mechanisms in elderly patients: characterization,
prevention and treatment of imbalanced oral microbial communities. Supervisors: prof.dr. W. Crielaard &
prof.dr. J.M. ten Cate; co-supervisors: dr. P.W de Groot, dr. J.J. de Soet & dr. E. Zaura, start: April 2007.
Graduation: June 16, 2014.
Krikken, JB. Dental anxiety and behaviour management problems; the role of parents. Supervisor: prof.dr. J.M.
ten Cate; co-supervisors: dr. J.S.J. Veerkamp & dr. A.J. van Wijk, start: January 2005.
Laheij, AMGA. Prospective study of changes in the oral biofilm and the protein composition of salivain
patients, being irradiated for a tumour in the head-and-neck area. Supervisor: prof.dr. C. van Loveren; cosupervisor: dr. J.J. de Soet, start: December 2008.
Liang, Y-H. The influence of the use of CBCT on endodontic outcome dtermination. Supervisor: prof.dr. P.R.
Wesselink; co-supervisors: dr. M.K. Wu & dr. H. Shemesh, start: 2010.
Louropoulou, A. Maintenance of peri-implant health, the evidence and guideline. Supervisor: prof.dr. G.A. van
der Weijden, start: 2010.
Macedo, RG de. Aspect of sodium hypochlorite as a root canal irrigant Supervisor: prof.dr. P.R. Wesselink; co-
52
supervisor: dr. L.W.M van der Sluis, start: October 2010.
Matse, JH. The diagnostic role of mucin expression in tissue and saliva in patients with salivary gland tumors.
Supervisors: prof.dr. E. Bloemena & prof.dr. E.C.I. Veerman; co-supervisor: dr. J.G.M. Bolscher, start:
September 2008.
May, A. Bioinformatic analysis for oral metagenomics. Supervisors: prof.dr. W. Crielaard & prof.dr. J. Heringa;
co-supervisors: dr. B.W. Brandt & dr. S. Abeln, start: August 2012.
Metska, ME. Cone beam CT in endodontic diagnostic. Supervisor: prof.dr. P.R. Wesselink; co-supervisor: dr.
A.R. Özok, start: October 2009.
Mevissen-Renckens, EHM. PTSD in individuals with intellectual disabilities. Supervisors: prof.dr. A. de Jongh &
prof.dr. R. Didden, start: 2010.
Moghimi, M. Head and neck infections. Supervisor: dr. T. Forouzanfar, start: 2011.
Moinzadeh, ATM. Quality assessment of root canal obturation. Supervisor: prof.dr. P.R. Wesselink; cosupervisor: dr. H. Shemesh, start: 2012.
Neelakantan, P. Supervisor: prof.dr. P.R. Wesselink; co-supervisor: dr. H. Shemesh, start: 2012.
Papantonopoulos, GH. Mathematical modeling of periodontitis. Supervisor: prof.dr. B.G. Loos, ACTA, start:
2012.
Persoon, IF. Molecular ecology and novel treatments in endodotic infections. Supervisors: prof.dr. W. Crielaard
& prof.dr. P.R. Wesselink, start: 2010.
Prodan, A. Saliva and oral health. Supervisors: prof. dr. E.C.I. Veerman; co-supervisors: dr. H.S. Brand & dr. F.J.
Bikker, start: September 2012.
Rademacher, WMH. Oral complications in oncological treatment. Supervisors: prof.dr. F.R Rozema, prof.dr. J.
de Lange. Start August 2013.
Ramawadh, RS. Molecular aspects of tissues around dental implants in oral oncology patients after
radiotherapy. Supervisors: prof.dr. E. Bloemena, prof.dr. E.A.J.M. Schulten & prof.dr. C.M. ten Bruggenkate;
co-supervisor: dr. N. Bravenboer, start: 2011.
Rijkschroeff, P. The function of oral PMNs in health and disease. Supervisor: prof.dr. B.G. Loos; co-supervisor:
dr. E.A. Nicu, start: 2013.
Roos de, C. Treatment of children following a potential traumatic incident. Supervisors: prof.dr. A. de Jongh &
prof.dr. Emmelkamp, start 2008.
Rosema, NAM. Toothbrushing efficacy. Supervisor: prof.dr. G.A. van der Weijden, co-supervisors: prof.dr. W.H.
van Palenstein Helderman & prof.dr. U. van der Velden, ACTA, start: 2006.
Scheerman, JFM. Supervisors: prof.dr. G.H.W. Verrips & prof.dr. C. Van Loveren, start: September 2012.
Schreuder, WH. Treatment options in central giant cell granuloma. Supervisor: prof.dr. J. de Lange, start:
January 2010.
Sijbrandij, T. Application of antimicrobial peptides as anti-warfare therapeutics. Supervisors: prof. dr. E.C.I.
Veerman; co-supervisors: dr. F.J. Bikker & dr. A.J.M. Ligtenberg,start: March 2010.
Sleen van der, J. Dento-alveolaire chirurgie. Supervisor: prof.dr. J. de Lange, start: April 2012.
Slot, D.E. Chlorhexidine gels and dental lasers in the prevention and therapy of periodontal disease.
Supervisor: prof.dr. U. van der Velden, co-supervisor: prof.dr. G.A. van der Weijden, ACTA, start: 2010.
Tabeian, H. Arthritis models for the Temporo Mandibular Joint. Supervisors: prof.dr. V. Everts & prof.dr. F.
Lobbezoo; co-supervisors: dr. A.D. Bakker & dr.ir. T.J. de Vries, start: 2012.
Teeuw, WJ. Relationships between periodontitis an general health: focus on diabetes and cardiovasculair
disease. Supervisor: prof.dr. B.G. Loos, start: October 2010.
Tuk, JC. Anxiety and pain related to oral and maxillofacial surgery. Co-supervisors: dr. J.A.H. Lindeboom & dr.
A.J. van Wijk, start: September 2012.
Veerbeek, HJ. Treatment of feelings of revenge. Supervisor: prof.dr. A. de Jongh; co-supervisor: dr. M.M.J.
Kunst, start :2012.
Vermaire, JH. Optimizing oral health. Towards a tailored, effective and cost-effective dental care. Supervisors:
prof.dr. W.B.F. Brouwer & prof.dr. C. van Loveren; co-supervisors: prof.dr. J. Hoogstraten & dr. J.H.G.
Poorterman, start: januari 2005.
Vermeer, AF. The effect of bisphosphonates on different osteoclast populations. Supervisor: prof.dr. V. Everts;
co-supervisor: dr.ir. T.J. de Vries, start: January 2010.
Verstraaten, S. Quality of life aspects oral and maxillofacial surgical procedures. Co-supervisors: dr. J.A.H.
Lindeboom & dr. A.J. van Wijk, start: September 2012.
Vleugel, B. van der Treatment of trauma in psychosis (TTIP)1. Supervisors: prof.dr. A. de Jongh &prof. M. van
der Gaag, start :2011.
53
Volgenant, CMC. Red fluorescence in dental plaque. Supervisor: prof.dr. J.M. ten Cate; co-supervisor: dr.ir.
M.H. van der Veen, start: 2010.
Waal, SV. van der Novel strategies for endodontic treatments. Supervisors: prof.dr. P.R. Wesselink & prof.dr.
W. Crielaard; co-supervisor: dr. J.J. de Soet, start 2009.
Zande, MM. van der Digital dentistry in practice: On dentists’ interaction with technological transformation.
Supervisor: prof.dr. D. Wismeijer; co-supervisor: dr. R.C. Gorter, start: February 2012.
Zecha, JAEM. Effect van lage intensiteit laser behandeling (LLLT) op bestralingsmucositis van het
mondslijmvlies. Supervisor: prof.dr. L.E. Smeele, start: January 2013.
54
Program Leader
Prof.dr. V. Everts
Department of Oral Cell Biology
ACTA Gustav Mahlerlaan 3004
1081 LA Amsterdam
Tel: +31-20-5980882
E mail: [email protected]
Full professors
A.G. Becking
C.M. ten Bruggenkate A.J. Feilzer
S. Gibbs
J. Klein-Nulend
J. de Lange
F. Lobbezoo
F.J.M. Roeters
P.F. van der Stelt
D.B. Tuinzing
E.A.J.M. Schulten
M. Naeije
D. Wismeijer
Introduction
The human masticatory system has several important functions that determine an individual’s general health
and well-being, like biting, chewing, swallowing, talking, laughing, and yawning. Sometimes, patients are
confronted with problems in performing these functions. This may have various causes. On the one hand,
chemical and bacteriological factors may hamper a healthy functioning of the masticatory system by causing
infection and inflammation. On the other hand, mechanical overloading as well as underloading or disuse of
the constituent structures of the masticatory system (viz., teeth, bone, cartilage, muscles, and joints) may yield
functional oromandibular impairments. Importantly, trauma or disease may result in damaged tissues which in
turn result in functional oromandibular impairments. The research of ACTA’s research program “Oral
Regenerative Medicine” (ORM) focuses on regenerating damaged oral tissue by means of stem cell therapy or
tissue engineering techniques, taking into account the mechanical threats for the masticatory system and
inflammatory reactions involved in tissue repair.. Relevant clinical problems are used to guide the research
55
aimed at developing novel solutions for these clinical problems. Groups that are involved in ORM-ACTA are
Oral Kinesiology (OKI), Oral Implantology and Prosthodontics (IMP), Dental Materials Sciences (DMS), Oral Cell
Biology and Functional Anatomy (OCB/FA), Oral Radiology (ORA), Orthodontics (ORT), and Oral and
Maxillofacial Surgery (OMS), both of the Academic Medical Center (AMC) and of the VU Medical Center
(VUmc).
The Interfaculty MOVE Research Institute has chosen “Regenerative Medicine” as one of its domains (i.e., a
collaboration of researchers within the VU campus on a key topic). Likewise, ORM has been formulated as one
of the two priority areas (“zwaartepunt”) of ACTA. As implied above, a healthy oral system is characterized not
only by the absence of infection and/or inflammation of dental and periodontal tissues, but also by a healthy
musculoskeletal system and oral mucosa. Musculoskeletal tissues (i.e., bone, cartilage, muscles, and joints)
and mucosa (epithelium and underling connective tissue) can be damaged or even destroyed by, for example,
mechanical overloading, disuse, disease or trauma. In case of tissue loss, the replacement or regeneration of
degenerating/degenerated cells, tissues, or organs is needed to restore or establish normal function (Mason A,
Dunnill PA. A brief definition of regenerative medicine. Regen Med 2008;3(1):1-5). ORM studies these
processes both at a fundamental and translational level in multidisciplinary settings, in which dentistry/oral
medicine closely collaborates with medical disciplines like orthopaedics, neurology and dermatology/ plastic
surgery, both within and outside The Netherlands. The main objectives of ORM-related research are: (1) to
develop strategies to prevent degeneration of oral tissues and/or organs by understanding the mechanisms of
tissue homeostasis and repair, and (2) to develop minimally invasive, regenerative treatment strategies when
prevention fails and treatment is required. Clearly, a focus on early diagnosis will play an important role in
repairing tissue damage before it becomes too extensive.
Tissue regeneration is possible by means of guiding stem cells and differentiated cells to repair and regenerate
damaged tissue with the aid of custom-designed biomaterials (matrices), mechanical loading, and nutrients
(viz., growth factors, hormones, and medication). Stem cells can be differentiated into bone, cartilage, muscle
cells and oral mucosa and it is the understanding of the interactions between these different cell types and
biomaterials together with the impact of mechanical loading and their interaction with the implanted area
which is essential if optimal tissue regeneration and vascularized graft take without adverse reactions is to be
achieved in the future. Insight into tissue regeneration is obtained by comparing results from tissue culture
and animal models to computer simulations of the motor system and to biomechanical research in clinical
trials with patients.
The outcome of all ORM’s research efforts will be an increased understanding of degenerating/degenerated
oral tissues and an improved ability to replace or regenerate these tissues, thereby restoring oral function and
thus oral health-related quality of life.
Research objectives
Overview
The research of ORM focuses on the effects of events that damage or even destroy oral tissue (e.g., tumor
removal, trauma accidents), including the effects of mechanical overloading or underloading on the tissues of
the masticatory system, on the resulting clinical problems, as well as on the solutions for these clinical
problems. These events have detrimental consequences for the constituent structures of the masticatory
system (viz., the teeth, the periodontal tissues, the alveolar bone, the skeletal bone, cartilage, the mucosa, and
the jaw musculature). Tissue damage and breakdown can occur, which may in turn cause clinical signs and
symptoms of the intra-oral structures and/or of the maxillo-mandibular structures. For example, patients may
report to the clinic of the dentist, orthodontist, or oral and maxillofacial surgeon with symptoms like tooth
wear, tooth mobility, tooth loss with or without bony defects, pain in the masticatory muscles or in the
temporomandibular joints, or dysfunction of the musculoskeletal structures (e.g., a reduced maximal mouth
opening). Hard to heal lesions may develop in the oral mucosa as a result from radiation/ chemotherapy after
tumor removal, extensive tooth extraction, or trauma. All of these signs and symptoms may yield complaints
of a reduction or even a loss of normal oral and mandibular functions. Apart from these physical complaints,
comorbid factors like an impaired psychosocial functioning and a reduced oral health-related quality of life are
commonly found in patients with pain and dysfunction of the masticatory system as well. After a proper
diagnostic procedure, the health care professionals involved in the care of these patients may indicate
treatment and rehabilitation strategies with the aim to restore normal oral and mandibular functions,
following the principles of evidence-based dentistry.
56
Treatment planning and rehabilitation
Much research of ORM focuses on treatment and rehabilitation of impaired or lost ortho-mandibular function.
Two main approaches can be distinguished. First, fundamental studies are conducted to develop novel
advanced techniques, prior to clinical testing in patient studies (phase 1), taking into account all the regulatory
issues within NL and Europe for ‘’advanced therapy medical products’’ (ATMPs) and medical devices.
Noteworthy in this context are studies to: a) stimulate bone growth around dental implants and into bone
defects; b) close oral mucosa lesions with tissue engineered mucosa when native autograft mucosa is limiting,
c) safety assessment of novel and existing biomaterials to predict adverse events during the pre-clinical phase,
d) study of the interaction of the cells and biomaterials to be implanted with wound healing mediators derived
from the implant site (wound bed) as the inflammatory status will influence graft take and vascularaization, e)
fabricate dental restorations using computer-aided design and manufacturing (CAD/CAM); f) use tissue
engineering and regenerative medicine techniques, focussing on the collagen network and adipose stem cells;
and g) improve the microcirculation in patients undergoing, for example, radiotherapy for malignancies.
st
Second, phase 1 (safety and 1 efficacy) and phase 2 randomized clinical trials are performed to test novel
constructs described above and to add the evidence base of treatment modalities. In this context, systematic
reviews and meta-analyses are regularly performed. In addition, evidence-based guidelines are developed for
application in clinical practice.
Results obtained in 2013
Tissue regeneration and engineering
•
•
•
•
•
•
•
A novel role for CD27 in osteoclast formation was established. Bone marrow osteoclast precursors
express this molecule. Interaction with CD70, which is expressed on activated immune cells, skews
differentiation towards dendritic cells.
Osteonecrosis is a common side-effect of high dosage bisphosphonate use. Bisphosphonates are
commonly used drugs that inhibit osteoclasts by causing osteoclast apopoptosis. Long bones are not
prone to this side effect. It was now shown that mouse jaw marrow cells that are driven towards
osteoclast differentiation take up more bisphosphonate than long bone marrow cells, thus indicating
bone-site specific responses to bisphosphonates.
Dietary magnesium deficiency could cause osteoclasts to resorb bone, thus compensating for the
deficiency. The effect of magnesium deprivation on osteoclasts was studied in vitro. Deficiency caused an
increased osteoclastogenesis, both from long bone and from jaw bone marrow cells.
We studied how cultured stem cells and keratinocytes will interact with soluble wound healing mediators
present within the wound bed after transplantation. Upon transplantation keratinocytes are primarily
activated to promote wound closure. In contrast, dermal fibroblasts and in particular adipose derived
stem cells (ASC) respond vigorously to factors present in the wound bed leading to increased secretion of
angiogenesis/granulation tissue formation factors. These findings have implications for the choice of cell
type (ASC or dermal fibroblast) to be used in regenerative medicine strategies and indicates the
importance of taking into account interactions with the wound bed when developing advanced therapies
for difficult to close cutaneous wounds (eg burns and ulcers).
We have described human maxillary sinus floor elevation as a model for bone regeneration enabling the
application of one-step surgical procedures. In addition, we reported a novel approach revealing the effect
of a collagenous membrane on osteoconduction in maxillary sinus floor elevation with β-tricalcium
phosphate. We reported growth factor gene expression profiles of bone morphogenetic protein-2-treated
human adipose stem cells seeded on calcium phosphate scaffolds in vitro. Finally, we reported important
differences in proliferation, differentiation, and cytokine production by bone cells seeded on titaniumnitride and cobalt-chromium-molybdenum surfaces.
A model for cell-mechanics studies has been published for testing the influence of nanostructural
environment and fluid flow on osteoblast-like cell behavior. Using this model, we found that endothelial
nitric oxide synthase is not essential for nitric oxide production by osteoblasts subjected to fluid shear
stress in vitro. A review paper on nitric oxide signaling in mechanical adaptation of bone is published. We
also used the model for cell-mechanics to show that strontium ranelate, an anti-osteoporotic drug, affects
signaling from mechanically-stimulated osteocytes towards osteoclasts and osteoblasts.
In collaboration with researchers from different institutes, among which VUmc, it was found that X-linked
PLS3 mutations cause osteoporosis and fractures. This finding has attracted much attention, and has been
57
•
•
•
•
•
•
published in the New England Journal of Medicine.
Developmental defects in pH- regulating transmembrane molecules can affect the structure of enamel
and bone. We recently detected in mouse ameloblasts (the cells that produce enamel) several new pHregulating molecules including NKCC1, NKCC2, Slc26A3 and SLc26A6. These molecules are well known pHregulators and ion-transporters in pancreatic and renal tubular epithelium. A transmembrane molecule
(SPPL2a) isolated from brain and present in B-cells was also expressed by mouse ameloblasts. Disruption
of the Sppl2a gene in mice caused severe enamel defects, indicating the relevance of this protein for
formation of enamel.
Muscle fibers adapt to functional demands. In a study to unravel the mechanism behind this adaptation
process it has been demonstrated that in particular so-called hybrid fibers adapt more easily to their
mechanical environment than other fibers.
In order to quantify the local deformation of bone, electronic speckle pattern inferometry has been
successfully applied as a new technique to approximate the deformations of the whole cortex under
influence of bone loading. This enables to validate finite element models that had been constructed to
predict the relationship between bone loading and deformation.
A considerable heterogeneity of the cortical bone-mineral density was found in the mandibles of adult
rabbits. The heterogeneous mineral-density distribution might serve to suppress bone-strain amplitudes
in regions architecturally susceptible to larger deformations during loading.
Biomechanical analysis of the effects of a fractured mandibular neck and its treatment by
maxillomandibular fixation have demonstrated that altered articulation in the temporomandibular joint
may give rise to disturbances in mandibular movements and dysocclusion. Furthermore, the treatment
does not necessarily prevent the mandibular condyle to dislocate.
Bonding to dentin is still a challenge, especially in difficult accessible areas like the root channel system.
Some fundamental aspects and novel bonding procedures were investigated. Furthermore, the strength,
and fatigue- and the bonding properties of zirconia were investigated. Zirconia can be used as restorative
material for dental crowns and bridges, but it can be also an alternative for metal implants. Understanding
the surface properties of zirconia is therefore ongoing research.
Clinical signs, symptoms and diagnosis
• Two systematic reviews of the literature assessed the prevalence of (sleep-related) bruxism in adults and
children, respectively. Both studies suggest that bruxism is a common condition in both populations.
However, there is a high variability in findings due to methodological shortcomings. Both papers provide
suggestions for future studies on this topic.
• Polysomnographically recorded sleep bruxism and periodic limb movements during sleep were shown to
have a common underlying neurophysiological mechanism associated with arousals in the electroencephalogram. While polysomnography is the gold-standard diagnostic tool for sleep bruxism, self
reports and clinical assessments for this condition were only poorly correlated.
• A research protocol was developed for the assessment of associations between masticatory activity and
quality of life in elderly persons with a dementia. For the assessment of masticatory activity, a two-colour
chewing gum test was developed and tested for its reliability and feasibility for use in this difficult and
fragile patient population.
• For the assessment of pain in patients with Down syndrome, modified versions of the facial affect scale
and of the numeric rating scale are recommended. Any application must be preceded by a comprehension
assessment. A systematic assessment of the literature could not identify a specific pattern of behavioural
pain indicators in people with intellectual disabilities.
• An experimental study suggested that temporomandibular disorder (TMD) pain is a manifestation of
delayed-onset muscle soreness. When myogenous TMD pain is provoked by means of hypertonic saline
injections, a reorganization of increasing and decreasing muscle activities occurs. For the clinical diagnosis
of TMD pain, a finding of familiar pain on dynamic/static testing yields diagnoses that are the least
influenced by comorbidities like depression and somatisation.
• Tooth wear rather than TMD pain has a negative impact on a patient’s quality of life. This impact is
comparable with that of edentulousness.
• Adverse reactions of metals to the skin are common. Also adverse oral reactions can be related to the use
of metals. The use of palladium (Pd) salt, sodium tetrachloropalladate, showed that Pd allergy is much
more common than previously assumed. Based on the high incidence of Pd and Ni allergy, which are also
cross-reactive, it is advisable to ban Pd out of dental applications.
58
•
•
•
•
•
A survey amongst Dutch Dentists showed large differences in the motivation to adopt and use digital
technologies in everyday practice. There were only a few enthusiastic early adaptors meaning that there is
a distinct role for those involved in teaching in dentistry to take this into account
Preclinical safety testing of new (and existing) biomaterials is essential before these substances are used in
humans. If such prior safety testing is not performed, implanted biomaterials may result in an
inflammatory reaction eg. allergy or irritancy. Within a European and American collaboration, and in full
compliance with the 3Rs, an in vitro human epithelial equivalent model has been developed (in our
laboratory) and tested internationally to identify potentially sensitizing from irritant or non-irritant
substances and to determine the potency (strength) of the sensitizer/irritant.
Field of View in CBCT influences the depiction of trabecular microstructure in human mandible.
Grey values in CBCT systems significantly deviated from Hounsfield unit values measured with MSCT.
Field of View FOV and spatial resolution and number of projections had a significant influence on grey
valu measurements in CBCT images.
Cephalometric soft-tissue evaluation from a recording of a patient in supine position is generally reliable,
except for the throat-chin area where a clinically relevant difference was found. The contour of the
submandibular tissues in supine position causes the chin to appear more prominently. This may cause
incorrect orthodontic diagnosis and treatment planning.
Treatment and rehabilitation
• 83 patients with 99 therapy resistant ulcers were treated with a novel full thickness tissue engineered skin
construct in an extensive phase 1 multicentre study. No related adverse events occurred and wounds
became revitalized resulting in healing. A hospital exemption has now been given by IGZ to treat all
patients with chronic skin wounds with this ATMP skin construct in NL who cannot be included in a clinical
study.
• In a community dental care population, mandibular advancement devices could be indicated and
monitored successfully in patients with obstructive sleep apnea (OSA) and snoring. At the same time, a
randomized clinical trial with occlusal stabilization splints were shown to worsen an existing OSA in some,
but not all patients. The findings of both studies have immediate clinical implications.
• Care-seeking of patients with temporomandibular disorder (TMD) pain is mainly determined by personrelated characteristics, like catastrophizing, assertiveness, and a critical attitude towards healthcare.
Improvement of TMD-pain complaints over a 6-month period is best predicted by the number of care
practitioners attended (positive) and the degree of hindrance on function (negative).
• Tooth colour and the colour and discolouration of restorations are still a challenge for the dentist and
scientist. The focus of the research was on the perceptibility and acceptability thresholds for colour
differences.
• Research on the efficacy and precision of intra oral scanners as a substitute for non-digitized impression
techniques shows that there is still a lot to win in the precision and time involved when using these
techniques
•
In a literature review on the use of digital implant planning tools the precision of these show a high
variety of results and these are user and system dependent. We found that patients with an overdenture
in the maxilla supported by two implants prefer to have the palate uncovered by the denture base when
taking aesthetics and taste into account.
• We found that patients fitted with an overdenture on two implants in the maxilla show an increased
satisfaction level, less psychological discomfort, less physical and social disability as well as increased
chewing ability, speech and general satisfaction (OHIP).
• We introduced a new classification of peri-implant bone defects in implant patients based on a long term
radiological follow-up of 110 patients over 16 years.
• We showed in a multi-center trial that the function of bilateral distal extension removable partial dentures
supported by distally placed implants significantly increased patient satisfaction during function.
• We showed that long term outcomes of crowns supported by short implants in the posterior regions af
the jaw can be a predictable treatment outcome.
• An anatomically shaped cranial collimator was designed to reduce radiation exposure in cephalomatric
imaging. The shape of the area shielded by this collimator was based on mean measurements of
cephalometric landmarks of 100 orthodontic patients. The collimator reduces the irradiated area by
almost one-third without interfering with the imaging system or affecting the image quality.
59
Research staff ACTA – ORM Oral Regenerative Medicine
(in full time equivalents)
position
Full professors
Senior lecturers
Lecturers and other tenured
staff
60
Name
Becking, prof.dr. A.G.
Bruggenkate, prof.dr. C.M. ten
Everts, prof.dr. V.
Everts, prof.dr. V.
Feilzer, prof.dr. A.J.
Gibbs, prof.dr. S.
Klein Nulend, prof.dr. J.
Lange, prof.dr. J. de
Lobbezoo, prof.dr. F.
Naeije, prof.dr.ir. M.
Prahl-Andersen, prof.dr. B.
Roeters, prof.dr. F.J.M.
Stelt, prof.dr. P.F. van der
Tuinzing, prof.dr. D.B.
Wismeijer, prof.dr. D.
Zentner, prof.dr. A.
Bronckers, dr. A.L.J.J.
Habets, dr. L.L.M.H.†
Kleverlaan, dr. C.J.
Koolstra, dr.ir. J.H.
Kuitert, dr. R.B.
Sanderink, dr. G.C.H.
Tahmaseb, dr. A.
Visscher, dr. C.M.
Algera, dr. T.J.
Baart, drs. J.A.
Bakker, dr. A.D.
Berkhout, dr. W.E.R.
Bos, dr. A.
Dalen, dr. A., van
Dubois, drs. L.
Forouzanfar. dr. T.
Geraets, dr. W.G.M.
Goené, drs. R.J.
Hassan, dr. B.A.
Jongsma, dr. L.A.
Koutris, drs. M.
Langenbach, dr. G.E.J.
Liu, dr. Y.
Liu, dr. Y.
Oers, dr.ir. R.F.M. van
Prahl, dr. C.
Selms, dr. M.K.A. van
fte 2013
0,10
0,10
0,20
0,05
0,05
0,30
0,80
0,10
0,40
0,05
pm
0,20
0,10
0,20
0,10
0,10
0,10
pm
0,50
0,10
0,10
0,50
0,05
0,60
0,20
0,05
0,30
0,50
pm
0,10
0,80
0,05
0,40
0,10
0,10
0,20
0,60
0,05
0,40
0,15
0,30
0,40
0,05
0,70
0,15
0,60
0,05
0,20
plan 2014
0,10
pm
0,20
0,05
0,05
0,30
0,80
0,10
0,40
pm
Pm
0,20
0,10
pm
0,10
0,10
0,10
pm
0,50
0,10
-0,50
0,05
0,60
0,20
0,05
0,30
0,50
pm
0,10
0,80
0,20
0,40
0,10
0,10
0,20
0,60
--0,15
0,30
0,40
-0,70
0,15
0,60
0,05
0,20
funding
1
1
1
2
1
1
1
1
1
1
guest
3
1
1
1
1
3
guest
1
3
1
1
3
1
1
1
1
1
guest
1
1
1
1
1
1
1
3
1
1
1
1
1
1
1
3
1
1
1
Position
Lecturers and other tenured
staff
Name
Verheij, dr. H.G.C.
Vries, dr.ir. T.J. de
Wu, dr. G.
Total tenured staff
Non tenured staff
Aarab, dr. G.
Al Kurwi, A.S.A.
Alfartousi, S.
Apperloo, drs. R.C.
Ashton, dr. C.E.
Atallah, drs. M.M.
Baggen, drs. J.H.M.
Bruggeman, dr. J. P.
Bucci, drs. R.
Byraki, drs. A.A.
Chin Jem Sen, drs. J.
Damaskos, dr. S.
Diaz-Serrano, dr. K.
Disse, drs. M.A.
Dozic, dr. A.
Elmi, P.
Fabels, L.N.J.
Faloni, drs. A.P.
Faure, drs. E.
Fernands, drs. G.
Gaalman, J.M.M.G.
Graven, drs. K.M.L.
Guo, J.
Hermus, R.R.
Hoogeveen, MSc. R.C.
Hove, R. van
Iskender, S.Y.
Jager, dr.ir. N., de
Jager, dr. D.H.J.
Joosten, M.W.
Kaaij, drs. N.C.W. van der
Knibbe, drs. W.
Koning, M.J.W.
Korstjens, dr. C.M.
Kramer, dr. G.J.C.
Loon, dr. J.J.W.A. van
Marpaung, drs. C.M.
Noverraz, drs. R.L.M.
Oosterhuis, M.
Parvaneh, drs. H.
Parys, K. van
Prins, dr. H-J.
Ramdat Missier, R.H.
Reyes Sevilla, drs. M.
fte 2013
0,60
0,65
0,15
0,80
13,45
0,10
pm
pm
0,10
0,20
pm
pm
0,20
pm
pm
pm
pm
pm
pm
pm
pm
pm
pm
pm
pm
pm
pm
0,70
pm
0,20
pm
pm
0,05
0,15
pm
pm
0,05
pm
0,15
pm
0,10
0,25
0,55
pm
pm
pm
pm
pm
0,15
pm
pm
plan 2014
0,30
0,65
0,15
0,80
12,35
0,30
pm
pm
0,10
0,10
pm
pm
0,20
pm
pm
pm
pm
pm
pm
pm
pm
pm
pm
pm
pm
pm
pm
0,70
pm
0,20
pm
pm
0,05
0,15
pm
pm
0,05
pm
-pm
0,10
0,25
0,55
pm
pm
pm
pm
pm
-pm
pm
funding
3
1
2
1
1
guest
guest
1
1
guest
guest
2
guest
guest
guest
guest
guest
guest
guest
guest
guest
guest
guest
guest
guest
guest
3
guest
1
guest
guest
3
1
guest
guest
1
guest
3
guest
1
2
3
guest
guest
guest
guest
guest
1
guest
guest
61
Position
Non tenured staff
PhD students
62
Name
Suijkerbuijk, drs. E.
Tabassum, dr. A.
Thymi, drs. M.
Uijlenbroek, drs. H.J.J.
Vermeulen, F.M.J.
Vervoorn-Vis, drs. G.
Vries, L. de
Wetselaar, drs. P.
Wezel. N.M. van
Willems, dr. N.M.B.K.
Wolff, dr. J.E.H.
Wolff, dr. J.E.H.
Zandieh Doulabi, dr.ing. B.
Zembic, dds. A.
Zygogiannis, dds. K.
Alharbi, dds.N.M.
Baas, drs. E.M.
Bastidas Coral, dds. A.P.
Bergh, drs. B. van den
Blaauboer, drs. M.E.
Bouwman, drs. W.F.
Bronoosh, dds. P.
Bruin, MSc. B.J.Q. de
Buskermolen, MSc. J.K.
Chalil, S.
Chen, dds. C.
Chen, dds. H.
Delwel, drs. S.
Derksen, W.D.C.
Dicker, dr. G.J.F.M.
Fazaeli, MSc. S.
Fezari, S.
Esterik, MSc. F.A.S. van
Glim, J.E.
Gooren, MSc. E.E.
Gregor, dds. L.
Harkel, MSc. B. ten
Ibrahim, dds. N.
Jong, MSc. T. de
Juffer, MSc. P.
Karssemakers, drs. L.H.E.
Khashayar, drs. G.
Kommers, MSc. S.C.
Liu, drs. T.
Maningky, drs. M.S.
Martin, drs. W.J.J.M.
Milheiro, dds. A.
Muris, drs. J.
Muzalev, drs. K.
Nolte, drs. J.W.
Oomens, drs. M.A.E.M.
fte 2013
pm
0,30
pm
pm
pm
pm
pm
0,10
pm
-0,10
0,10
0,80
0,05
0,60
pm
0,10
0,05
pm
0,20
pm
pm
pm
0,55
pm
0,60
0,20
0,25
pm
pm
0,75
pm
0,75
pm
0,25
pm
0,75
0,65
0,75
0,05
pm
0,50
0,30
0,60
pm
pm
0,50
0,30
pm
pm
pm
plan 2014
pm
0,30
pm
pm
pm
pm
pm
0,10
pm
0,15
-0,60
0,80
-0,60
pm
-0,75
pm
-pm
pm
pm
0,70
pm
-0,70
0,25
pm
pm
0,75
pm
0,75
pm
-pm
0,75
0,10
0,75
-pm
-0,05
-pm
pm
0,50
0,30
pm
pm
pm
funding
guest
3
guest
guest
guest
guest
guest
1
guest
1
1
3
1
3
3
guest
3
1
guest
1
guest
guest
guest
1
guest
3
3
3
guest
guest
1
guest
1
guest
1
guest
2
3
1
1
guest
1
1
3
guest
1
1
1
guest
guest
guest
Position
fte 2013
pm
pm
0,65
0,75
0,20
0,15
pm
0,10
0,10
0,05
0,20
pm
pm
pm
pm
0,75
0,40
0,20
pm
0,75
0,75
0,75
0,30
19,20
22,15
plan 2014
pm
pm
0,40
0,75
--pm
--0,05
0,20
pm
pm
pm
pm
0,75
0,40
0,10
pm
-0,75
0,75
0,30
16,10
19,45
funding
guest
guest
3
3
1
1
guest
3
3
guest
3
guest
guest
guest
guest
1
1
1
guest
1
2
3
3
nd
2,15
2,15
2
rd
8,35
32,65
6,85
28,45
3
PhD students
Total non tenured staff
st
total 1 funding
total 2 funding
total 3 funding
Name
Ossendorp, R.
Overman, drs. J.R.
Parsa, dds. A.
Pathak, MSc. J.L.
Renders, drs. G.A.P.
Rhee, MSc. A.K. van der
Rollman, mw. A.
Rozeboom, drs. A.V.J.
Ruiter, drs. M.H.T. de
Ruiz Zapata, MSc. A.M.
Ruslin, dds. M.
Rutten, S.
Salentijn, drs. E.
Scholtanus, drs. J.C.
Stoker, drs.ir. G.T.
Tabeian, MSc. H.
Tastepe, dds. C.S.
Tuijt, drs. M.
Velzen, drs. F.J.J. van
Vermeer, MSc. A.F.
Vorselen, MSc D.
Wang, dds. D.
Zande, MSc. M.M. van der
1
Output
Dissertations
Blaauboer, M.E. (2013, September 24). Cell matrix interactions in lung fibrosis. VU University Amsterdam (143
pag.). Prom./coprom.: prof.dr. V. Everts, prof.dr.ir. T.H. Smit & dr. R. Stoop.
Chen, C. (2013, September 27). Zirconia-reinforced dental restorations. Universiteit van Amsterdam (117 pag.).
Prom./coprom.: prof.dr. A.J. Feilzer & dr. C.J. Kleverlaan.
Irshad, M. (2013, December 19). Host-bacterial interaction in peri-implantitis. VU University Amsterdam (162
pag.). Prom./coprom.: prof.dr. W. Crielaard, prof.dr. B.G. Loos, prof.dr. D. Wismeijer & dr. M.L. Laine.
Juffer, P. (2013, November 18). Muscle and bone a common world? Biological pathways in muscle and bone
adaption to mechanical loading. VU University Amsterdam (147 pag.). Prom./coprom.: prof.dr. J. Klein
Nulend, prof.dr. P.T.A.M. Lips, R.T. Jaspers & dr. A.D. Bakker.
Kalenderian-Groenewegen, E. (2013, October 02). EZCodes: A diagnostic terminology as the foundational step
of quality for the dental profession. Universiteit van Amsterdam (195 pag.). Prom./coprom.: prof.dr. A.J.
Feilzer & prof.dr. R.B. Donoff.
Khashayar, G. (2013, November 28). Color science in dentistry. VU University Amsterdam (174 pag.).
Prom./coprom.: prof.dr. A.J. Feilzer, dr. A. Đozic & dr. C.J. Kleverlaan.
Koutris, M. (2013, October 28). Masticatory muscle pain: Causes, consequences, and diagnosis. Universiteit
van Amsterdam (128 pag.). Prom./coprom.: prof.dr.ir. M. Naeije, prof.dr. F. Lobbezoo & dr. C.M. Visscher.
Liu, T. (2013, September 18). Osteoinductive bone substitutes. VU University Amsterdam (180 pag.).
Prom./coprom.: prof.dr. D. Wismeijer, prof.dr. Z. Gu & dr. Y. Liu.
63
Rollman, A. (2013, November 27). Improvement and care seeking for temporomandibular-pain complaints:
The complexity of chronic pain. Universiteit van Amsterdam (134 pag.). Prom./coprom.: prof.dr.ir. M.
Naeije, dr. C.M. Visscher & dr. R.C. Gorter.
Rutten, S. (2013, January 18). Low-intensity pulsed ultrasound treatment in delayed bone healing. VU
University Amsterdam (163 pag.). Prom./coprom.: prof.dr. J. Klein Nulend, prof.dr. P.I.J.M. Wuisman & dr.
P.A. Nolte.
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cell-mechanics studies. Acta Biomaterialia, 9(5), 6653-6662.
Prodanov, L., Loon, J.J.W.A. van, Riet, J. te, Jansen, J.A. & Walboomers, X.F. (2013). Substrate nanotexture and
hypergravity through centrifugation enhance initial osteoblastogenesis. Tissue Engineering. Part A, 19(1-2),
114-124.
Rachmawati, D., Bontkes, H.J., Verstege, M.I., Muris, J., Blomberg, B.M.E. von, Scheper, R.J. & Hoogstraten,
I.M.W. van (2013). Transition metal sensing by Toll-like receptor-4: next to nickel, cobalt and palladium are
potent human dendritic cell stimulators. Contact Dermatitis, 68(6), 331-338.
Reitsma, J.H., Elmi, P., Ongkosuwito, E.M., Buschang, P.H. & Prahl-Andersen, B. (2013). A longitudinal study of
dental arch morphology in children with the syndrome of Crouzon or Apert. European Journal of Oral
Sciences, 121(4), 319-327.
Reitsma, J.H., Ongkosuwito, E.M., Buschang, P.H., Adrichem, L.N.A. van & Prahl-Andersen, B. (2013).
Craniofacial stability in patients with Crouzon or Apert syndrome after Le Fort III distraction osteogenesis.
Cleft Palate-Craniofacial Journal, 50(5), 561-569.
Rollman, A., Visscher, C.M., Gorter, R.C. & Naeije, M. (2013). Improvement in patients with a TMD-pain
report. A 6-month follow-up study. Journal of Oral Rehabilitation, 40(1), 5-14.
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Rollman, A., Gorter, R.C., Visscher, C.M. & Naeije, M. (2013). Why seek treatment for temporomandibular
disorder pain complaints? A study based on semi-structured interviews. Journal of Orofacial Pain, 27(3),
227-234.
Ruiz-Zapata, A.M., Kerkhof, M.H., Zandieh-Doulabi, B., Brölmann, H.A.M., Smit, T.H. & Helder, M.N. (2013).
Fibroblasts from women with pelvic organ prolapse show differential mechanoresponses depending on
surface substrates. International Urogynecology Journal, 24(9), 1567-1575.
Salehi-Nik, N., Amoabediny, G., Pouran, B., Tabesh, H., Shokrgozar, M.A., Haghighipour, N., Khatibi, N., Anisi, F.,
Motthagy, K. & Zandieh-Doulabi, B. (2013). Engineering parameters in bioreactor's design: a critical aspect
in tissue engineering. BioMed Research International, 2013(762132).
Salentijn, E.G., Bergh, B. van den & Forouzanfar, T. (2013). A ten-year analysis of midfacial fractures. Journal
of Cranio-Maxillofacial Surgery, 41(7), 630-636.
Scholtanus, J.D., Hoorn, W. van der, Ozcan, M., Huysmans, M.C.D.N.J.M., Roeters, J.F.M., Kleverlaan, C.J. &
Feilzer, A.J. (2013). Staining of dentin from amalgam corrosion is induced by demineralization. American
Journal of Dentistry, 26(4), 185-190.
Schulten, E.A.J.M., Prins, H-J., Overman, J.R., Helder, M.N., Bruggenkate, C.M. ten & Klein-Nulend, J. (2013).
A novel approach revealing the effect of a collagenous membrane on osteoconduction in maxillary sinus
floor elevation with beta-tricalcium phosphate. European Cells & Materials, 25, 215-228.
Selms, M.K.A. van, Visscher, C.M., Naeije, M. & Lobbezoo, F. (2013). Bruxism and associated factors among
Dutch adolescents. Community Dentistry and Oral Epidemiology, 41(4), 353-363.
Serrano, P., Loon, J.J.W.A. van, Javier Medina, F. & Herranz, R. (2013). Relation between motility, accelerated
aging and gene expression in selected Drosophila strains under hypergravity conditions. Microgravity
Science and Technology, 25(1), 67-72.
TM
Snijders, R.S., Wijk, A.J. van & Lindeboom, J.A. (2013). A comparative study of the Osstell versus the Osstell
TM
Mentor to evaluate implant stability in human cadaver mandibles. Journal of Oral Rehabilitation, 40(10),
774-779.
Šperka, J., Souček, P., Loon, J.J.W.A. van, Dowson, A., Schwarz, C., Krause, J., Kroesen, G. & Kudrle, V. (2013).
Hypergravity effects on glide arc plasma. European Physical Journal D, 67(261).
Tastepe, C.S., Liu, Y., Visscher, C.M. & Wismeijer, D. (2013). Cleaning and modification of intraorally
contaminated titanium discs with calcium phosphate powder abrasive treatment. Clinical Oral Implants
Research, 24(11), 1238-1246.
Valstar, M.H., Baas, E.M., Rijdt, J.P. te, Bondt, B.J de, Laurens, E. & Lange, J. de (2013). Maxillary sinus
recovery and nasal ventilation after Le Fort I osteotomy: a prospective clinical, endoscopic, functional and
radiographic evaluation. International Journal of Oral and Maxillofacial Surgery, 42(11), 1431-1436.
Wijk, A.J. van, Lobbezoo, F. & Hoogstraten, J. (2013). Reliability and validity of a continuous pain registration
procedure. European Journal of Pain, 17(3), 394-401.
Verhoeven, T.J., Nolte, J.W., Maal, T.J.J., Bergé, S.J. & Becking, A.G. (2013). Unilateral condylar hyperplasia: a
3-dimensional quantification of asymmetry. PLoS One, 8(3), e59391.
Vermeer, J.A.F., Jansen, I.D.C., Marthi, M., Coxon, F.P., McKenna, C.E., Sun, S., Vries, T.J. de & Everts, V.
(2013). Jaw bone marrow-derived osteoclast precursors internalize more bisphosphonate than long-bone
marrow precursors. Bone, 57(1), 242-251.
Versari, S., Klein-Nulend, J., Loon, J. van & Bradamante, S. (2013). Influence of oxygen in the cultivation of
human mesenchymal stem cells in simulated microgravity: an explorative study. Microgravity Science and
Technology, 25(1), 59-66.
Vuorjoki-Ranta, T.R., Lobbezoo, F., Tuomilehto, H., Könönen, M., Pihakari, A. & Ahlberg, J. (2013). Mandibular
advancement devices in the treatment of obstructive sleep apnea and snoring in community dental care: A
pilot study on self-reported sleep quality. Health, 5(8A2), 1-5.
Weijenberg, R.A.F., Lobbezoo, F., Knol, D.L., Tomassen, J. & Scherder, E.J.A. (2013). Increased masticatory
activity and quality of life in elderly persons with dementia-a longitudinal matched cluster randomized
single-blind multicenter intervention study. BMC Neurology, 13, 26.
Weijenberg, R.A.F., Scherder, E.J.A., Visscher, C.M., Gorissen, T., Yoshida, E. & Lobbezoo, F. (2013). Two-colour
chewing gum mixing ability: digitalisation and spatial heterogeneity analysis. Journal of Oral Rehabilitation,
40(10), 737-743.
Wismeijer, D., Tawse-Smith, A. & Payne, A.G.T. (2013). Multicentre prospective evaluation of implant-assisted
mandibular bilateral distal extension removable partial dentures: patient satisfaction. Clinical Oral Implants
Research, 24(1), 20-27.
Xiao, Y.L., Song, J.Y., Vries, T.J. de, Fatmawati, C., Parreira, D.B., Langenbach, G.E.J., Babala, N., Nolte, M.A.,
Everts, V. & Borst, J. (2013). Osteoclast precursors in murine bone marrow express CD27 and are impeded
69
in osteoclast development by CD70 on activated immune cells. Proceedings of the National Academy of
Sciences of the United States of America, 110(30), 12385-12390.
Yu, N., Oortgiesen, D.A.W., Bronckers, A.L.J.J., Yang, F., Walboomers, X.F. & Jansen, J.A. (2013). Enhanced
periodontal tissue regeneration by periodontal cell implantation. Journal of Clinical Periodontology, 40(7),
698-706.
exploration of barriers and incentives to adopting digital technologies. British Dental Journal, 215(11), 1-5.
Scientific publications (non refereed)
Bruggenkate, C.M. ten & Schulten, E.A.J.M. (2013). Flapless implant surgery (or not?). In R. Ewers & J.T.
Lanbrecht (Eds.), Oral Implants - Bioactivating Concepts (pp. 5.3-413-418). London, UK: Quitessence
Publishing Co. Ltd.
Koolstra, J.H. (2013). Finite analysis of the temporomandibular joint. Section III. Biomechanics of TMJ function.
In D.M. Laskin & C.S. Greene (Eds.), Treatment of temporomandibular disorders: bridging the gap between
advances in basic research and clinical patient management (1st edition) (pp. 10: 113-121). Quintessence
Pub Co.
Osiewicz, M.A., Lobbezoo, F., Loster, B.W., Wilkosz, M., Naeije, M. & Ohrbach, R. (2013). Research Diagnostic
Criteria for Temporomandibular Disorders (RDC/TMD): The Polish version of a dual-axis system for the
diagnosis of TMD.* RDC/TMD form. Journal of Stomatology, 66(5), 576-649.
Prahl, C. (2013). Presurgical orthopedics. In S. Berkowitz (Ed.), Cleft lip and palate: diagnosis and management,
3rd edition (pp. 455-473-20). Springer.
Salehi-Nik, N., Amoabediny, G., Ahmadizadeh, R., Heli, B. & Zandieh-Doulabi, B. (2013). Hydrodynamically
stable adhesion of endothelial cells on gelatin electrospun nanofibrous scaffolds. APCBEE Procedia,
00(2013), 161-166.
Selms, M.K.A. van, Visscher, C.M., Naeije, M. & Lobbezoo, F. (2013). Letter to the editor. Journal of Orofacial
Pain, 27(2), 183.
Visscher, C.M. & Hertogh, W. (2013). Cervicogenic mechanisms of orofacial pain and headaches. In R. de
Leeuw & G.D. Klasser (Eds.), Orofacial pain. Guidelines for assessment, diagnosis, and management, fifth
edition (pp. 8: 187-201). Quintessence Publishing Co, Inc.
Wijk, A.J. van, Lobbezoo, F. & Hoogstraten, J. (2013). Authors' reply to the comment by Sabour. European
Journal of Pain, 17(3), 462.
Wetselaar, P., Vermaire, J.H. & Lobbezoo, F. (2013). Multidisciplinary treatment of tooth wear in a patient
with Asperger’s Syndrome and dental anxiety. Journal of Craniomandibular Function, 5(1), 55-69.
Wu, G. & Liu, Y. (2012). Histological methods for analysis of bone-implant interface. In A. Ballo (Ed.), Implant
dentistry research guide: basic, translational and experimental clinical research (Dental science, materials
and technology) (pp. 293-324). New York: Nova Science Publishers.
Akker, H.P. van den & Baart, J.A. (2013). Lokale complicaties. In J.A. Baart & H.S. Brand (Eds.), Lokale
anesthesie in de tandheelkunde, tweede herziene druk (pp. 91-108). Houten: Bohn Stafleu van Loghum.
Baart, J.A. (2013). Aanvullende anesthesietechnieken. In J.A. Baart & H.S. Brand (Eds.), Lokale anesthesie in de
tandheelkunde, tweede herziene druk (pp. 109-119). Houten: Bohn Stafleu van Loghum.
Baart, J.A. (2013). Algemene praktische aspecten. In J.A. Baart & H.S. Brand (Eds.), Lokale anesthesie in de
Baart, J.A. (2013). Lokale anesthesie in de bovenkaak. In J.A. Baart & H.S. Brand (Eds.), Lokale anesthesie in de
Baart, J.A. (2013). Lokale anesthesie in de onderkaak. In J.A. Baart & H.S. Brand (Eds.), Lokale anesthesie in de
Baart, J.A. (2013). Omgaan met vreemd gedrag. Quality Practice. Nascholingstijdschrift voor Tandartsen, 9(3),
24-27.
Baart, J.A. & Allard, R.H.B. (2013). Pijnstillers in de tandheelkunde. Quality Practice. Nascholingstijdschrift
70
Becking, A.G. (2013). Adaptatie van kauwspieren na chirurgische behandeling [Bespreking van het boek
Adaptation of jaw muscles after surgical mandibular advancement]. Nederlands Tijdschrift voor
Berkhout, W.E.R. (2013). Evidence-based diagnostiek. Quality Practice.
Nascholingstijdschrift voor
Berkhout, W.E.R. (2013). Röntgendiagnostiek. Quality Practice. Nascholingstijdschrift voor Tandartsen, 8(5),
21-25.
Berkhout, W.E.R. (2013). Straling. Quality Practice. Nascholingstijdschrift voor Mondhygiënisten, 6(1), 32-35.
Berkhout, W.E.R. (2013). Stralingsrisico's en verantwoordelijkheden. Quality Practice Assistenten, 1(1), 22-25.
Bonn, C.E.H.M., Selms, M.K.A. van, Poel, F. te, Visscher, C.M., Lobbezoo, F. & Naeije, M. (2013). Onderscheid
tussen temporomandibulaire pijn en andere vormen van orofaciale pijn op basis van een vragenlijst.
Boverhoff, J.C. & Baart, J.A. (2013). Parotitis epidemica, een meldingsplichtige ziekte. Nederlands Tijdschrift
voor Tandheelkunde, 120(1), 22-26.
Dalen, A. van (2013). Witte tanden. Quality Practice Assistenten, 1(1), 14-18.
Everts, V. (2013). Proefschriften 25 jaar na dato 34. Collageenafbraak door fibroblasten en osteoclasten.
Feilzer, A.J., Kleverlaan, C.J., Prahl, C. & Muris, J. (2013). Systemische reacties op in de mond toegepaste
metaallegeringen. Nederlands Tijdschrift voor Tandheelkunde, 120(6), 335-341.
Gibbs, S. (2013). Synergy in regenerative medicine. Per 1st July 2012 appointed for the Fenna Diemer
Lindeboom chair as Professor of Skin and Mucosa Regenerative Medicine (2012, March 08). Amsterdam:
VU University medical center.
Hoogeveen, R. (2013). Cone beam CT, wat moet ik ermee? Quality Practice. Nascholingstijdschrift voor
Karssemakers, L.H.E., Gilijamse, M. & Baart, J.A. (2013). Inslikken of aspireren van een voorwerp dat in de keel
verdwijnt. Nederlands Tijdschrift voor Tandheelkunde, 120(2), 63-66.
Kloet, H.J. de & Roeters, J.F.M. (2013). Esthetische tandheelkunde in het kindergebit. In W.E. van Amerongen,
L.C. Martens, G. Stel & J.S.J. Veerkamp (Eds.), Kindertandheelkunde 2. - 2e herz. druk (pp. 40: 169-194).
Koutris, M. & Lobbezoo, F. (2013). Myofasciale pijn bij temporomandibulaire disfunctie: een manifestatie van
vertraagde inspanningsspierpijn (DOMS)? Quality Practice. Nascholingstijdschrift voor Tandartsen, 8(4), 1619.
Langenbach, G.E.J. (2013). Anatomie van de nervus trigeminus. In J.A. Baart & H.S. Brand (Eds.), Lokale
anesthesie in de tandheelkunde, 2e herziene druk (pp. 2:19-36). Houten: Bohn Stafleu van Loghum.
Lobbezoo, F., Toxopeus, A.H., Delwel, S., Weijenberg, R.A.F. & Scherder, E.J.A. (2013). Orofaciale
pijndiagnostiek bij ouderen met een dementie. Quality Practice. Nascholingstijdschrift voor Tandartsen,
8(4), 8-11.
Lobbezoo, F. (2013). De mens achter de mond. In N. Beetstra & A. van Kempen (Eds.), Quality Practice. Henk
(pp. 32-34). Houten: Prelum.
Lobbezoo, F. & De Meyer, M.M.D. (2013). Slaapgerelateerde bewegingsstoornissen: bruxisme. In J.
Verbraecken, B. Buyse, H. Hamburger, V. van Kasteel & R. van Steenwijk (Eds.), Leerboek slaap &
slaapstoornissen (pp. 600-604). Leuven: Acco.
Muris, J. (2013). Ongewenste neveneffecten van toegepaste tandheelkundige materialen. Quality Practice.
Naeije, M. (2013). Kaakgewrichtsklachten: concepten en controversen. Quality Practice. Nascholingstijdschrift
Roeters, J., Jongsma, L.A. & Kleverlaan, C.J. (2013). Hoe beperken we ongewenste neveneffecten van
technieken en materialen? Quality Practice. Nascholingstijdschrift voor Tandartsen, 9(3), 16-22.
Ruiter, M.H.T. de, Apperloo, R.C. & Lange, J. de (2013). Bimaxillaire osteotomie als mogelijke behandeling
voor ernstig obstructieve slaapapneu. Nederlands Tijdschrift voor Tandheelkunde, 120(9), 470-474.
Schulten, E.A.J.M. (2013). Reconstructie van kaakdefecten na chirurgische tumorbehandeling: chirurgische en
prothetische mogelijkheden. Quality Practice. Nascholingstijdschrift voor Tandartsen, 8(3), 42-49.
Selms, M.K.A. van & Lobbezoo, F. (2013). Bruxisme bij Nederlandse jongeren. Quality Practice.
Stelt, P.F. van der (2012). Afscheid van Cees de Baat als hoofdredacteur. Nederlands Tijdschrift voor
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Stelt, P.F. van der (2013). Je moet het gezien hebben...Visualisatie in de radiologie. Quality Practice.
Stelt, P.F. van der (2013). Cone beam-computertomografie in de orthodontie [Bespreking van het boek Cone
beam CT in orthodontics]. Nederlands Tijdschrift voor Tandheelkunde, 120(9), 500.
Valstar, M.H., Jaspers, G.W. & Lange, J. de (2013). Ontoereikende diagnostiek bij een fractuur van het collum
mandibulae. Nederlands Tijdschrift voor Tandheelkunde, 120(3), 151-153.
Vanderveken, O., Braem, M., Hoekema, A. & Lobbezoo, F. (2013). Behandeling van OSA: Mandibulaire
repositieapparaten. In J. Verbraecken, B. Buyse, H. Hamburger, V. van Kasteel & R. van Steenwijk (Eds.),
Leerboek slaap & slaapstoornissen (pp. 473-477). Leuven: Acco.
Visscher, C.M., Ligthart, L. & Lobbezoo, F. (2013). Is TMD-pijn erfelijk? Quality Practice. Nascholingstijdschrift
Visser, B.E. de & Rossum, B.P. van (2013). Zijn kaakklachten toch erfelijk? Nederlands Tandartsenblad, 68(3),
20-23.
Warnsinck, C.J., Shemesh, H. & Lobbezoo, F. (2013). Persisterende pijn na endodontische behandeling.
Wetselaar, P., Wesemael-Suijkerbuijk, E. van & Lobbezoo, F. (2013). Een gebitsslijtagecasus aan de hand van
het Gebitsslijtage Beoordelings Systeem. Quality Practice. Nascholingstijdschrift voor Tandartsen, 8(4), 2028.
Wismeijer, D. (2013). Peri-implant tissue remodeling. Duidelijke opbouw [Bespreking van het boek Periimplant tissue remodeling. Scientific background and clinical implications]. Nederlands Tandartsenblad,
68(6), 25.
Wit, R. de, Berg, M.A.G. van den, Tuut, M.K., Amelsfoort, P. van, Beerthuizen, A., Berg, J.S.P. van den, Bomhof,
M., Bont, L.G.M. de, Boven, R. van, Dekker, F., Engels, J.H.B., Helder, J.C., Huygen, F., Koopman, J.S.H.A.,
Lever-Wiersema, P., Lobbezoo, F., Lynch, H., Mooij, J.J.A., Mulleners, W., Nauta, N., Passchier, J., Ru, J.A.
de, Samwel, H., Simon, M., Stegenga, B., Tjakkes, G-H., Tusscher, M.P.M. ten, Vanneste, J., Visscher, C.M.,
Warnsinck, J. & Zuurmond, W.W.A. (2013). Multidisciplinaire Richtlijn “Chronische Aangezichtspijn”, 136
pp.http://www.hoofdpijnpatienten.nl/images/stories/PDF/Richtlijnen/Richtlijnen_aangezichtspijn/Richtlijn
_pdf/Richtlijn%20aangezichtspijn%2021112013%20DEFINITIEF.pdf. Amersfoort: Nederlandse Vereniging
van Hoofdpijnpatiënten, authorized 21-11-2013.
Zaag, J. van der & Roeters, J.F.M. (2013). Restauratieve beslissingen: een casus. Quality Practice.
Publications aimed at the general public
Gibbs, S. (2013, March 11). Van tand tot blaas, van huid tot haar. Trouw.
Boer, S. de, Koolhaas, J.M. & Loon, J.J.W.A. van: NWO-ALW a 4 years PhD Grant: Title: “Coping with altered
gravity: orchestrating role of brain serotonin”.
Bronckers, A.L.J.J.: NIH grant on dental fluorosis a 3 year extension to end of 2014 (87 k US $ per year).
Bronckers, A.L.J.J.: NIH grant for joint collaboration between Oral Cell Biology ACTA, Amsterdam, Oral Biology,
Semmelweis University of Medicine, Budapest, Hungary and UCSF School of Dentistry, USA (US$ 52.000).
Chen, H. PhD project is financially supported by the China Scholarship Council (CSC).
Christiansen, C., Svensson, P. & Lobbezoo, F. Development of a user-friendly bruxism treatment device.
Fornyelsesfonden – Grøn Innovation, €117.000,-. Start project: 2012. End project: 2015.
Dental Oy Instrumentarium lends a OP300 CBCT unit for research and clinical purposes. Expected term: 3
years. Annual worth: ± € 20.000.
Everts, V. NIRM grant on multinucleated giant cells. PhD student, €280.000,- September 2011-2015.
Everts, V., Lenthe, H. van, Koolstra, J.H. & Lobbezoo, F. Biomechanical changes in articulation of the jaw joint
due to aging. EU-MOVE-AGE PhD Program.
Everts, V. Coordinator of FP7-PEOPLE-2013-Marie Curie ITN project EUROCLAST. Project with 7 academies and
two private companies. 11 ESRs € 3.100.000, September 2013-September 2017.
Feilzer, A.J., Klein Nulend, J., Kleverlaan, C.J. & Everts V. Research priority grant, University of Amsterdam,
€1.650.000,-, 2012-2016.
Forouzanfar, T. Klinische validatie van SPG-stimulatie in chronische clusterhoofdpijnpatiënten met het ATIneurostimulatieSysteem. Subsidiegever: Innovatiefonds zorgverzekeraars. € 300.000,-. Start: December
2013.
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Giminez, Hassan, B.A., Tahmaseb, A. & Wismeijer, D. 2013. Evaluation of a full digital workflow to fabricate
CAD/CAM implant frameworks from digital impressions. In vivo and in vitro analysis. (materials granted
separately). Granted € 57.000, 3M ESPE.
Giminez, Hassan, B.A., Tahmaseb, A. & Wismeijer, D. 2013. Evaluation of a full digital workflow to fabricate
CAD/CAM implant frameworks from digital impressions. In vivo and In vitro analysis. ( scholarship). Granted
€ 27.000, 3M ESPE.
Gorter R.C. & Wismeijer, D. International Team for Implantology (ITI): Digital dentistry in practice; on dentists’
Dentistry and Oral Implantology. February 2012 – December 2013: € 110.000,- .
Gucht, J. van der & Loon, J.J.W.A. van: NWO-ALW: 4 years PhD Grant: Title: “Self-organization and dynamics
of actin networks under microgravity conditions”.
Klein Nulend, J., Bruggenkate, C.M. ten, Schulten, E.A.J.M. & Helder, M.N. Bone augmentation with
autologous adipose tissue-derived mesenchymal stem cells, BMP-2 and calcium phosphate carrier in the
human maxillary sinus floor elevation model. Funding: ZonMW TAS project # 116001009 € 650.000, 20092013.
Klein-Nulend, J. & Bakker, A.D. Servier project: Effect of strontium ranelate on the osteocyte response to
mechanical loading and osteocyte communication towards osteoblasts. (PI: Klein-Nulend J, Co-PI: Bakker
AD), € 207,610, 1 fte postdoc, 1 fte technician for 1 yr, 2012.
Klein-Nulend, J. & Luyten, F.P. (Leuven): European Union: MOVE-AGE Erasmus Mundus Joint Doctorate
Program “Prevention of mobility loss with ageing”: The etiology of generalized osteoporosis in rheumatoid
arthritis. MOVE-AGE project € 180.000, 2011-2014.
Klein-Nulend, J., Helder, M.N. & Amoabediny, G. University of Tehran – Research Center for New Technologies
in Life Sciences Engineering - sponsored project: Skeletal tissue production using regenerative medicine
and adipose stem cell technology for large bone defects. 1 PhD student. € 200,000, project duration: 1 Oct
2013 – 1 Oct 2017,.
Lange, J. de & Apperloo, R.C. Dental implants as anchorage for prostheses; number, configuration and
suprastructure. Straumann. Duration of the project 2010-2015.
Lange, J. de & Jaspers, G.W. Medication in implant dentistry. Straumann. Duration of the project 2010-2015.
Lange, J. de & Rozeboom, A.V.J. Fractures of the condylar head. Synthes 2011-2014.
Lange, J. de. Oral appliance versus positional therapy. Nutsohra fonds. 2012-2014.
Lautenbacher, S., Achterberg, W., Husebo, B. & Lobbezoo, F. et al. Pain assessment in patients with impaired
cognition, especially dementia. EU-COST Action TD1005, €400.000,-. Start project: 2011. End project: 2015.
Liu, Y. & Wismeijer, D. 2012. Peri-implantitis project 46 Straumann implants. Granted inkind.
Lobbezoo, F. Validity of Grindcare® diagnosis of sleep bruxism. Medotech A/S Project Grant, € 13.532,80. Start
project: 2012. End project: 2013.
Muzalev, K., Yoshida, E., Wismeijer, D. & Lobbezoo F. Associations between sleep bruxism and peri-implant
complications: a follow-up study. NVGPT Onderzoekssubsidie, €5.000,-. Start project: 2012. End project:
2015.
Tabassum, A. Tahmaseb A., Liu, Y. & Wismeijer, D. CAMLOG Foundation: A modified drilling protocol for
implant site preparation and subsequent collection of bone autograft: A randomized controlled trial.
Granted € 73.210. September 2012.
Tabassum, A., Wu, G., Liu, Y. & Wismeijer, D. ITI grant: Granted € 36.000. February 2012.
Tahmaseb, A., Wismeijer, D. & Hassan, B.A. 2013. Immediate post extraction implant placement. Granted
inkind.
Veerman, E.C.I., Bolscher, J.G.M., Gibbs, S.,& Schepers, R. Technology Foundation STW. Novel saliva-derived
peptides for state-of-the-art clinical wound-healing applications. € 641.317, 2010-2014
Wismeijer, D. 2012. A pilot study looking at the treatment of edentulous patients with mini implants. Granted
€ 22.000.
Wismeijer, D. 2012. Comparing the immediate loading (within 48 hours) of two interconnected implants with
an overdenture to the immediate loading of 4 Mini Dental implants and an overdenture in a Randomized
Controlled Clinical trial. Granted € 213.727.
Wu, G. Liu, Y. & Wismeijer, D. ITI grant. Granted € 143.900, August 2012.
73
Editorship book
Baart, J.A. & Brand, H.S. (Eds.). (2013). Lokale anesthesie in de tandheelkunde. Tweede geheel herziene druk.
Koolstra, J.H. & Langenbach, G.E.J. (Eds.). (2013). Het gezicht - Atlas van de klinische anatomie, 1e druk.
Houten: Prelum.
Wismeijer, D., Chen, S. & Buser, D. (Eds.). (2013). The ITI treatment guide series Vol-6, first edition 2012.
Extended edentulous spaces in the esthetic zone. Translations in Spanish, German, French, Italian,
Portuguese, Japanese and Turkish (ITI treatment guide series, 6). Berlin: Quintessenz Verlags GmbH.
Memberships of editorial board
Aarab, G.:
Bronckers, A.L.J.J.:
Bruggenkate, C.M. ten:
Everts, V.:
Everts, V.:
Everts, V.:
Everts, V.:
Feilzer, A.J.:
Feilzer, A.J.:
Forouzanfar, T.:
Goené, R.J.:
Goené, R.J.:
Klein-Nulend, J.:
Klein-Nulend, J.:
Klein-Nulend, J.:
Klein-Nulend, J.:
Klein-Nulend, J.:
Klein-Nulend, J.:
Koolstra, J.H.:
Lobbezoo, F.:
Lobbezoo, F.:
Naeije, M.:
Prahl, C.:
Prahl, C.:
Prahl, C.:
Prahl, C.:
Sanderink, G.C.H.:
Sanderink, G.C.H.:
Stelt, P.F. van der:
Visscher, C.M.:
Journal of Dental Sleep Medicine.
Odontology.
Clinical Oral Implants Research.
International Journal of Dentistry.
International Journal of Oral Research.
The Open Bone Journal.
The Open Enzyme Inhibition Journal.
American Journal of Dentistry.
Odontology.
Medicina Oral
European Journal of Oral Implantology.
Journal of Implant and Reconstructive Dentistry.
Clinical Reviews in Bone and Mineral Metabolism.
Experimental and Clinical Endocrinology & Diabetes.
Journal of Musculoskeletal Research.
The Open Biology Journal.
The Open Nitric Oxide Journal.
The Open Tissue Engineering and Regenerative Medicine Journal.
Journal of Dental Biomechanics.
Journal of Craniomandibular Function.
Journal of Oral Rehabilitation.
Journal of Oral Rehabilitation.
Cleft Palate-Craniofacial Journal.
European Journal of Orthodontics.
Orthodontics and Craniofacial Research.
The Angle Orthodontist.
Dentomaxillofacial Radiology.
Oral Radiology
Clinical Oral Implants Research.
Dentomaxillofacial Radiology.
Journal of Dentistry Shiraz University of Medical Sciences.
Odontology.
Journal of Craniomandibular Function.
Scientific awards/honours
Loon, J.J.W.A. van (2013). The first international recipient of the Orr Reynolds Distinguished Service Award
from the American Society for Gravitational and Space Research (ASGSR). 29th ASGSR meeting: Orlando,
Florida, USA (2013, November 04 - 2013, November 08).
Sanderink, G.C.H. (2013). Honorary Membership. 19th Congress International Association DentoMaxilloFacial
Radiology: Bergen, Norway (2013, June 26).
74
Organization of (inter)national scientific congresses and symposia
Everts, V. (2013). Organizer. Two day conference Dutch Society Calcium and Bone Metabolism: Woudschoten,
the Netherlands (2013, November 14 - 2013, November 15).
Gibbs, S. (2013). Organizer. A new dimension, symposium on 3D printing in medicine (CTRM): Amsterdam, the
Netherlands (2013, March 21).
Gibbs, S. (2013). Organizer. The Inaugural meeting, Centre for Translational Regenerative Medicine:
Amsterdam, the Netherlands (2013, January 10).
Gibbs, S. (2013). Organizer symposium Advanced Therapy Medicinal Products (ATMPs). CTRM workshop: The
changing world in Cellular therapies: Amsterdam, the Netherlands (2013, November 03).
Koutris, M. (2013). Member organizing committee. EACD: Bordeaux, France (2013, September 18 - 2013,
September 26).
Lobbezoo, F. (2013). Member organizing committee. IADR Workshop "Biomedical Ontology and Referent
Tracking: Introduction to Basic Principles": Seattle, CA (2013, March 20).
Lobbezoo, F. (2013). Member organizing committee. IADR Sattelite Symposium "Orofacial Pain Assessment:
Classification, Biobehavior, QST and Biomarkers": Seattle, CA (2013, March 19).
Lobbezoo, F. (2013). Member organizing committee. International Consensus Workshop “Expanded TMD
taxonomy for further classification research”: Seattle, CA (2013, March 18).
Lobbezoo, F., Naeije, M. & Visscher, C.M. (2013). Members organizing committee. 28th Store Kro Meeting:
Amsterdam, the Netherlands (2013, May 19 - 2013, May 22).
Stelt, P.F. van der (2013). Organizer. CARS 2013, Computer Assisted Radiology and Surgery: Heidelberg,
Germany (2013, June 26 - 2013, June 29).
Wismeijer, D. (2013). Organizer. ITI congress Benelux: Antwerp, Belgium (2013, April 19 - 2013, April 21).
Wismeijer, D. (2013). Organizing committee. 5th ITI consensus conference Kursaal, Berne: Bern, Switzerland
(2013, April 23 - 2013, April 27).
Invited speakers at (inter)national congresses or symposia
Berkhout, W.E.R. (2013, September 21). Radiologie en richtlijnen. Hasselt, Belgium, Jaarsymposium Verbond
der Vlaamse Tandartsen.
Bruggenkate, C.M. ten (2013, July 11). Komplicationen. München, Germany, Implantologie congress.
Bruggenkate, C.M. ten (2013, May 16). Sinus floor elevation. Cascais, Portugal, NVOI congress.
Delwel, S. (2013, October 12). Challenges of orofacial pain assessment in elderly with dementia. 2nd
Amsterdam Symposium on Palliative Care, Vrije Universiteit, Amsterdam, the Netherlands, Research
meeting.
Delwel, S. (2013, April 04). Orofacial pain in dementia. Clermont Ferrand, European Spring School 2013,
European Cooperation in Science and Technology, Centre de Pharmacology.
Everts, V. (2013, November 21). Bone remodeling, recent insights. Istanbul, Turkye, Yeditepe University,
Dental Faculty.
Gibbs, S. (2013, March 13). Allergenicity testing of chemicals from an innate immunology perspective.
Amsterdam, the Netherlands, European Immunology workshop.
Gibbs, S. (2013, June 21). New developments in tissue engineered in vitro assays. Troisdorf, Germany, Cell
Systems BV.
Gibbs, S. (2013, June 27). New developments in tissue engineered wound healing and scar models. Lubeck,
Germany, 4th Regenerative Medicine symposium.
Gibbs, S. (2013, September 01). Skin models and dendritic cell migration. Interlaken, Switzerland, Eurotox.
Goené, R.J. (2013, September 28). Aesthetics through innovations. Philadelphia, USA, American Academy of
Periodontology.
Goené, R.J. (2013, January 11). Mastering esthetics in post-extraction sites. Madrid, Spain, 2nd European
Symposium.
Klein-Nulend, J. (2013, June 24-28). 6 lectures on cell biology of bone. Centre International des Sciences
Mechanoques (CISM), Advanced School, Bone Cell and Tissue Mechanics, Udine, Italy.
Klein-Nulend, J. (2013, October 25). NO signaling in mechanical adaptation of bone. Cebu City, Philippines,
Biophysics Symposium, 31st Samahang Pisika ng Philipinas, Physics Congress.
Klein-Nulend, J. (2013, October 16). Research in dentistry inspires orthopaedics. Venice, Italy, Symposium
Cross-disciplinary inspiration for orthopaedic practice and research, CORS 2013, 8th combined meeting
Orthopaedic Research Societies.
75
Koolstra, J.H. (2013, July 31). Biomechanical analysis of fractures in the mandibular neck (collum mandibulae).
Dunedin, New Zealand, Sir John Walsh Research Institute - Annual Research Day.
Koutris, M. (2013, June 01). Myogenous TMD. Athens, Greece, Symposium on Orofacial Pain, Dental
Association of Athens.
Kuijs, R.H. (2013, September 06). Tooth wear, to treat or not to treat. What are the questions? Eye,
Amsterdam, the Netherlands, ACTA-DE International Tooth Wear Congress: 4 clinical approaches 4 tooth
wear.
Kuitert, R.B. (2013, March 21). 1. Development of overbite and vertical facial dimensions during and after
orthodontic treatment. 2. Frequency, correction and development of contact points between anterior
teeth after orthodontic treatment. 3. Relation between long term post treatment development of upper
and lower anterior crowding and retention time and post retention period. Soestduinen, the Netherlands,
NVvO voorjaarscongres Vereniging van Orthodontisten.
Lobbezoo, F. (2013, November 16). 1. Treating bruxism. Present facts and treatment perspectives. 2. Sleep
medicine in the dental office. 3. Chewing over bruxism. Bad Homburg, Germany, Seminar Deutschen
Gesellschaft fur Funktionsdiagnostik und –therapie.
Lobbezoo, F. (2013, April 29). Are bruxism and the bite causally related? Amsterdam, the Netherlands, Lecture
Journal of Oral Rehabilitation online congress: Critical Update on Occlusion, ACTA.
Lobbezoo, F. (2013, April 18). Kauwen op bruxisme. Antwerpen, Belgium, Keynote Lecture, International
Congress “Bruxisme, bijten en slijten”, Vlaamse Wetenschappelijke Vereniging voor Tandheelkunde.
Lobbezoo, F. (2013, September 27). The DC/TMD expanded. Bordeaux, France, EACD.
Lobbezoo, F. (2013, June 07). The management of sleep apnea in dentistry. Napoli, Italy, Italian Society of
TMD/OFP (SIDA).
Schulten, E.A.J.M. (2013, June 28). Bone regeneration in the cranio-maxillo-facial (CMF) region: Current and
future treatment strategies. Amstelzaal VUmc, Amsterdam, the Netherlands, CTRM symposium: Towards a
new center for the treatment of complex osseous defects.
Stelt, P.F. van der (2013, August 19). Incidental findings on cone beam ct examinations. Las Vegas, NV, USA,
Keynote speaker, International conference on Dental and Oral health.
Tahmaseb, A. (2013, November 03). 1. Guided implant surgery. 2. Bone grafting. Hanghzou, China, TC Group
China 1st international congress on oral implantology.
Tahmaseb, A. (2013, November 28). Computer technology in implant dentistry. Kish, Iran, ITI meeting.
Tahmaseb, A. (2013, February 09). How guided is guided surgery. France, ITI congress.
Tahmaseb, A. (2013, April 23). New technologies in implant dentistry. Bern, Switzerland, ITI Consensus
meeting and congress.
Tahmaseb, A. (2013, April 19). The precision of guided surgery. Antwerp, Belgium, ITI congress Benelux.
Tuinzing, D.B. (2013, March 04). Farewell Lecture Prof.dr. Ch. Krenkel. Bad Hofgastein, 27th ICMFS World
Congress.
Tuinzing, D.B. (2013, March 13). How to start surgical orthodontic interaction. Indications /contraindication in
Surgical Orthodontics. Surgical demonstrations. Makassar, Indonesia, 4e Makassar Scientific meeting and
PDGI–FKG, Faculty of Dentistry, Hasanudin University.
Tuinzing, D.B. (2013, January 28). Surgical orthodontic lectures. Surgical demonstrations. Bandung, Indonesia,
Hasan Sadikin Hospital, Dental faculty University Pandandaran, Orthodontic department.
Tuinzing, D.B. (2013, November 28). Surgical Orthodontics: BSSO. Haarlem, the Netherlands, Woolly Wales
orthognatic symposium.
Wetselaar, P. & Wetselaar-Glas, M. (2013, January 25). 1. Bruxism. 2. TMD, diagnostic and treatment for the
general practitioner. Italy, Rio de Pousteria.
Wismeijer, D. (2013, September 11). 1. Implants in the edentulous patient. The Dutch approach. 2. Treatment
protocols for peri-implantitis. Bern, Switzerland, Universiteitl Berne (CH).
Wismeijer, D. (2013, December 05). 1. Implants in the edentulous patient.The Dutch approach. 2. Digital
solution in implant dentistry. Kish, Iran, Iranian congress on oral implantology.
Wismeijer, D. (2013, November 02). 1. The edentulous patient. The Dutch approach. 2. Risk factors in oral
implantology. 3. Esthetic aspects of oral implantology. Hanghzou, China, TC Group China 1st international
congress on oral implantology.
Wismeijer, D. (2013, April 27). Clinical guidelines as produced on the topics of CAD/CAM, implant abutment
materials and complications involving implant abutments and abutment material. Bern, Switzerland, ITI
Annual conference Bern. The 5th ITI consensus conference. Kursaal Berne (CH).
Wismeijer, D. (2013, November 28). Computer technology in implant dentistry. Kish, Iran, ITI meeting.
76
Wismeijer, D. (2013, September 12). Digital dentistry: are we aware of the impact? Bern, Switzerland, ZMK
Yearly symposium.
Wismeijer, D. (2013, February 01). Digitalization in implant dentistry. How to integrate this into everyday
practice. Sao Paulo, Brasil, CISOP I Congresso Interdisciplinar da APCD (Sao Paulo state Dental Association).
Wismeijer, D. (2013, February 07). Implants for the edentulous. The Dutch approach. Rio de Janeiro, Brasil, ITI
studyclubs of Rio de Janeiro combined with members of the prosthodontic and perio department of the
UERJ (Universidade do Estado do Rio de Janeiro).
Wismeijer, D. (2013, April 23). New technologies in implant dentistry. Bern, Switzerland, ITI Consensus
meeting and congress.
Wismeijer, D. (2013, October 17). What have we learned and where are we going to. Dublin, Ireland, EAO
Dublin, satellite symposium Camlog.
Wismeijer, D. & Aurajo, M. (2013, February 04). Implants for the edentulous. The Dutch approach. Porto
Alegre, Brasil, ITI studyclubs of Porto Alegre.
Zandieh Doulabi, B. (2013, November 05). Concepts in regenerative medicine. Tehran, Iran, Seminar University
of Tehran.
Other (inter)national scientific functions
Aarab, G.:
Berkhout, W.E.R.:
Berkhout, W.E.R.:
Berkhout, W.E.R.:
Disse, M.:
Disse, M.:
Gibbs, S.:
Gibbs, S.:
Goené, R.J.:
Klein Nulend, J.:
Klein Nulend, J.:
Klein Nulend, J.:
Klein Nulend, J.:
Koutris, M.:
Kramer, G.J.C.:
Kuitert, R.B.:
Lobbezoo, F.:
Lobbezoo, F.:
Lobbezoo, F.:
Lobbezoo, F.:
Lobbezoo, F.:
Member research committee American Academy of Dental Sleep Medicine
(AADSM).
Member Research and Scientific Committee European Academy of DentoMaxillo-Facial Radiology (EADMFR).
Member Central Council European Academy of Dento-Maxillo-Facial
Radiology (EADMFR).
Member Selection criteria and radiation protection committee European
Academy of DentoMaxilloFacial Radiology (EADMFR).
Member EFOSA on behalf of the NVvO.
Member RTS.
Member European Research Group for Experimental Contact Dermatitis
(ERGECD).
Member and principal investigator NIRM.
President Post-Academic Education Committee NVOI.
Directory board member of the MOVE Research Institute Amsterdam, VU
University Amsterdam, the Netherlands.
Member scientific board Department of Regenerative Medicine, Research
Centre for New Technologies in Life Science EngineerinKleing, University of
Tehran, Iran.
Member research assessment committee Group Biomedical Sciences (Dept.
Oral Health Sciences and Dept. Development and Regeneration), KU
Leuven, Belgium.
Founding member Micro-mechanical Tissue Repair Society.
Chair research committee European Academy of Craniomandibular
Disorders (EACD).
Chair Wetenschap en Accreditatie commissie NVvO.
Member Richtlijncommissie NVvO.
Member management committee .EU-COST Action TD-1005 (Pain
assessment in patients with impaired cognition, especially dementia).
Member working group 1 Psychometrics and Algesimetry .EU-COST Action
TD-1005 (Pain assessment in patients with impaired cognition, especially
dementia).
Member Grindcare Clinical Advisory Board (CAB) of the Danish company
Medotech, Denmark.
President-Elect International RDC/TMD Consortium Network, International
Association of Dental Research (IADR).
External examiner PhD thesis T. Maulina, September 2013 .University of
Sydney, Australia.
77
Loon, J.J.W.A. van:
Loon, J.J.W.A. van:
Loon, J.J.W.A. van:
Loon, J.J.W.A. van:
Loon, J.J.W.A. van:
Loon, J.J.W.A. van:
Loon, J.J.W.A. van:
Prahl, C.:
Prahl, C.:
Prahl, C.:
Sanderink, G.C.H.:
Visscher, C.M.:
Wetselaar, P.:
Wismeijer, D.:
Wismeijer, D.:
Wismeijer, D.:
Wismeijer, D.:
Wismeijer, D.:
Wismeijer, D.:
Wismeijer, D.:
Zandieh Doulabi, B.:
Zandieh Doulabi, B.:
Member scientific and program committee ELGRA Biennial Symposium and
General Assembly, Vatican City, Rome, Italy, 11-14 September 2013.
Member review board ESA Spin-Your-Thesis (SYT) and Drop-Your-Thesis
(DYT) educational programs; March 2013.
Member ESA Topical Team Advanced Compound Microscopy (From
Molecules to Organism Morphology). Coordinators Jürgen Bereiter-Hahn
(Goethe University Frankfurt am Main) and David Jones (Philipps University
Marburg), February 2013.
Reviewer European Commision REA-EC-SPACE-CALL 2012, Brussels,
Belgium, 4-8 February 2013.
Member management committee European Low Gravity Research
Association (ELGRA).
Member The Altered Gravity Platform: a Ground Based Research Facility for
Human United Nations / China Workshop on Human Space Technology
(UNOOSA-HSTI), Beijing, China, 16-20 September 2013.
Reviewer United Nations Office of Outer Space Affairs UNOOSA), Human
Space Technology Initiative (HSTI) program on space applications. ZeroGravity Instrument Project (ZGIP).
Board member NVOS.
Board member Stichting ter bevordering van de orthodontie.
Member study group USA: Angle Society North Atlantic Component.
Chairman Trustfund IADMFR.
Scientific advisor Kuwait University.
Board member Physical Therapy Board of Craniofacial and Cervical
Therapeutics (PTBCCT), USA.
Member committee Tandarts Gnathologen Nederlandse Vereniging voor
Gnathologie en Prothetische Tandheelkunde.
Chairman 5th ITI consensus conference group, Kursaal, Berne (CH): Clinical
guidelines as produced on the topics of CAD/CAM, implant abutment
materials and complications involving implant abutments and abutment
material.
Member Consensus conference Camlog Rome: 'Effect of the dept of implant
placement on boneloss around implants.
Honorary consultant Dental Clinic, School of Stomatology, Zhejing Chinese
Medical University, Hangzou.
Member scientific advisory board International Association of Digital
Dentistry (IADD).
Member ITI Education Committee.
Member ITI Research Committee.
Examiner Royal College of Surgeons of Scotland.
Visiting professor Research Center for New Technologies in Life Sciences
Engineering, University of Tehran, Iran.
Head Department Regenerative Medicine Research Centre for New
Technologies in Life Science Engineering, University of Tehran, Iran.
Supervisor of an external PhD student
Loon, J.J.W.A. van Co-supervisor of external PhD student L. Prodanov with thesis: "Bone biomaterials
engineering. Modification of cell and tissue response by mechanical stimulation an biomaterial
nanostructure". Supervisor: Prof.dr. J. Jansen, UMCN; co-supervisors: dr. J.J.W.A. van Loon, ACTA; dr. F.
Walboomers, UMCN Nijmegen, April 4, 2013.
Lobbezoo, F. Supervisor of external PhD student R.A.F. Weijenberg with thesis: The relationship between
chewing, cognition and depression in older persons with dementia. Supervisors: prof.dr. E.J.A. Scherder &
prof.dr. F. Lobbezoo VU University Amsterdam (242 pag.), 18-12-2013.
78
Societal impact
The societal impact of the programme is evident by, among others, the impact on patient care, interactions
with the industry and other non-university groups, the impact on professionals, and relevant (inter-)national
functions. The research program also contributes to the post-graduate training programs.
The research on overloading and pain of the musculoskeletal structures of the masticatory system has direct
impact on the quality of diagnostic procedures and of patient care, and extends its influence towards an
improvement of the (oral-) health-related quality of life. The implications of this research are not only
important for general orofacial pain patient groups, but also for more vulnerable populations like those
suffering from dementias and otherwise impaired cognitive abilities.
An ambitious future goal of the program is to improve health care and treatment of patients with juvenile
idiopathic arthritis. Diagnosis of arthritis of the jaw joint is commonly missed by clinicians, eventually possibly
leading to progressive pain and malfunctioning of the joint. Research started in 2012 is focused on learning the
biological parameters of the three types of cartilage present in the jaw joint. Inflammation will be mimicked in
vitro and it will be determined whether mechanical loading will lead to a decreased inflammation.
Special focus is on orthodontic patients with cranio-facial deformities and/or related malocclusions. A program
of quality of life related to this topic is carried out.
During the last couple of years it became clear that implanted materials like metals can have adverse effects
like allergy. This last subject is now an important issue of investigation. An improved understanding how
metals may induce an allergic reaction will have an enormous impact on the society.
The societal impact of the research on oral and maxillofacial radiology is focused on the improvement of
diagnostic imaging procedures. This relates to not only technical parameters, but also other factors that
influence the diagnostic performance of radio-diagnostic procedures, such as the effect of viewing conditions
and observer characteristics. Part of the activities includes continuing education courses on the safe use of
radiation in dental practice and application of digital imaging in dentistry.
Enamel fluorosis is an increasing aesthetic problem in several countries. The project on mechanism of enamel
fluorosis adds to our understanding how these defects develop which will help to prevent these defects in
future. The results of our research on bone adaptation and regeneration will offer multiple opportunities for
the development of new therapeutic agents to prevent (inflammation-associated) unwanted clinical bone loss,
thereby preventing among others mobility loss with aging.
The societal impact of the clinical research on oral and maxillofacial surgery is focussed on the influence on
patient care, both within the department and externally. Research contributes to improved treatment of
relevant patient groups.
More details of the societal impact of the program are listed below.
Radiology
The societal impact of the research on oral and maxillofacial radiology is focused on the improvement of
diagnostic imaging procedures and radiation safety. This relates to not only technical parameters, but also
other factors that influence the diagnostic performance of radio-diagnostic procedures, such as the effect of
viewing conditions and observer characteristics. Part of the activities includes continuing education courses on
the safe use of radiation in dental practice and application of ConebeamCT in dentistry. In 2013 the Ministries
of Social Affairs and Public Health officially recognized the ConebeamCT course of the department of Oral
Radiology as a ‘’Radiation Protection course’’.
Oral and Maxillofacial Surgery/Oral Pathology VUmc
The societal impact of the research of the department of Oral and Maxillofacial Surgery/Oral Pathology is
focussed on the influence on patient care, both within the department and externally. Research on all main
areas of interest contributes to improved prevention, diagnosis and treatment of relevant patient groups. The
societal impact is evident from the items listed below.
Several scientists of the program have contacts with the industry, see the list of current grants in de paragraph
of indicators of esteem above.
The department of Oral and Maxillofacial Surgery/Oral Pathology has collaborations with the firms Straumann
and Biohorizons related to maxillofacial implantology (Ten Bruggenkate, Schulten, Forouzanfar).
Department of Radiology: Instrumentarium Dental Oy, Finland.
Disse, M. Orthodontist in het schisisteam.
Kramer, G.J.C. Orthodontist schisisteam MCA.
79
Kramer, G.J.C. Voorzitter/secretaris Special Interest Group Orthodontics NVSCA.
Lobbezoo, F. Member of the Grindcare Clinical Advisory Board (CAB) of the Danish company Medotech.
Prahl C. Orthodontist in het schisisteam VUmc.
Visscher, C.M. Board member of the Physical Therapy Board of Craniofacial and Cervical Therapeutics
(PTBCCT), USA, 2003-present.
Impact of the research on the general public
Bedaf, M. Een kijkje in de kliniek voor Orale Kinesiologie. ACTA Quality Practice 2013;8(4):4-6.
Gibbs, S. Van tand tot blaas, van huid tot haar. Trouw, 11 March 2013.
Gibbs, S. (2013). Proefdieronderzoek moet nooit vanzelfsprekend zijn (interview). In De V van verhalen.
Persoonlijke verhalen over het Vervangen, Verminderen en Verfijnen van dierproeven (pp. 139-142).
Bilthoven: Nationaal Kenniscentrum Alternatieven voor dierproeven (NKCA).
Mantel, A. Niet vergeten: goed kauwen. De Telegraaf, 10 December 2013: T9.
MDLinx Editorial Team. www.mdlinx.com/dentistry/news-article.cfm/4362967; 2013. Oral health-related
quality of life in tooth wear patients.
Impact of the research on professionals
Patients are referred by their dentists to the various specialized clinics of the departments participating in the
program for diagnosis and treatment based on the latest scientific evidence.
The guidelines for diagnosis and treatment of patients have been adopted by the Dutch association for Oral
and Maxillofacial Surgery (Nederlandse Vereniging voor Mondziekten, Kaak- en Aangezichtschirurgie, NVMKA).
Lobbezoo, F. Member of the Dutch Society of Headache Patients Committee that develops a Guideline for the
Diagnosis and Treatment of Orofacial Pain.
Visscher, C.M.: Member of the Dutch Society of Headache Patients Committee that develops a Guideline for
the Diagnosis and Treatment of Orofacial Pain.
Forouzanfar, T., Schulten, E.A.J.M., Baart, J.A. & Karagozoglu, K.H. (2013). Organizers. Wintersymposium Oral
and Maxillofacial Surgery: Amsterdam, the Netherlands (2013, December 13).
Forouzanfar, T., Schulten, E.A.J.M., Baart, J.A. & Karagozoglu, K.H. (2013). Organizers. NVMKA
voorjaarsvergadering: Amsterdam, the Netherlands (2013, May 31).
Goené, R.J. (2013). Organizer. Jubileumcongres NVOI, Staying Integrated: Cascais, Portugal (2013, mei 16 2013, May 19).
Klein Nulend, J. (2013). Organizer. Osteo-Artrose Refereeravond (3x) under auspicies of the MOVE Research
Institute Amsterdam, VU University Medical Center, Amsterdam, NL; co-organizer: Prof.dr. W.F. Lems
(VUmc, Dept. Rheumatology): Amsterdam, the Netherlands (2013, November 14 - 2013, November 15).
Lobbezoo, F. & Wetselaar, P. (2013). Organizers. ACTA-DE International Tooth Wear Congress: 4 clinical
approaches 4 tooth wear: EYE, Amsterdam, the Netherlands (2013, September 06).
Prahl, C. (2013). Organizer. Schisiscongresdag VUmc/ACTA voor tandartsen en andere professionals:
Amsterdam, the Netherlands (2013, May 17).
Schulten, E.A.J.M., Goené, R.J. & Bruggenkate, C.M. ten (2013). Organizers. 5e Implantologie à VU
symposium, Een kwestie van kiezen, Amstelzaal VUmc: Amsterdam, the Netherlands (2013, May 28).
Wismeijer, D. 10-10-2013 Voorzitter studie club ITI Gelderland Hotel Avegoor te Ellecom 19.00 – 22.30 Periimplantitis.
Wismeijer, D. 17-12-2013 Voorzitter studie club ITI Gelderland Hotel Avegoor te Ellecom 19.00 – 22.30
Calcium Phosphate bone substitutes.
Invited speakers at professional congresses or symposia
Baart, J.A. (2013, November 15). De tand in al zijn facetten II. Rotterdam, the Netherlands, Congres de Doelen.
Baart, J.A. (2013, March 28). Pijn en pijnbestrijding. Pijn en het gebruik van pijnstillers in de tandheelkunde.
Leusden, the Netherlands, Dentalbest congres.
Bruggenkate, C.M. ten (2013, March 16). Augmentation. Amsterdam, the Netherlands, Implantologie à VU.
80
Bruggenkate, C.M. ten (2013, March 26). Implant success or failure. Gorinchem, the Netherlands, Course on
Implantology.
Bruggenkate, C.M. ten (2013, March 22). Sinuslifting. Putten, the Netherlands, NVOI het Fundament.
Bruggenkate, C.M. ten (2013, September 13). Sinuslifting. Putten, the Netherlands, NVOI het Fundament.
Bruggenkate, C.M. ten (2013, December 03). Stem cell project. Amsterdam, the Netherlands, CTRM congress
ACTA.
Forouzanfar, T. (2013, February 12). 3D printing and tissue engineering in maxillofacial surgery. Kuwait, Dental
Faculty, University of Kuwait.
Forouzanfar, T. (2013, March 17). 3D printing and tissue engineering in maxillofacial surgery. Makassar,
Indonesia, Indonesian Association of OMFS.
Forouzanfar, T. (2013, March 17). Stem cell and bone formation. Makassar, Indonesia, University of Makassar.
Goené, R.J. (2013, May 28). Immediate Fronttandvervanging. Amsterdam, the Netherlands, 5e Implantologie à
VU symposium. Een kwestie van kiezen, Amstelzaal VUmc.
Goené, R.J. (2013, March 27). Peri-Implantitis. Barchem, the Netherlands, Minisymposium tandartspraktijk
Wolsink.
Goené, R.J. (2013, March 08). Teamwork: all of us know more than one of us. Amsterdam, the Netherlands, ITI
Thema-avond.
Karssemakers, L.H.E. (2013, August 14). Een nieuw gezicht voor Nv assisterenden in MKA. CT bij UCH. Assen,
the Netherlands, 57e Najaarsvergadering NvMKA.
Lobbezoo, F. (2013, September 13). Bruxisme. Nijmegen, the Netherlands, Symposium “Nederlandse
Vereniging voor Orofaciale Fysiotherapie”.
Lobbezoo, F. & Delwel, S. (2013, November 21). Een gereedschapskist voor pijndiagnostiek bij non-verbale
ouderen. Amsterdam, the Netherlands, Duopresentation ACTA-DE Symposium 'Mondzorg bij ouderen'.
Lobbezoo, F. (2013, April 12). Slaapstoornissen, snurken en slaapapneu. ACTA, Amsterdam, the Netherlands,
WTA Spring Congress 2013 “Slaapstoornissen”.
Prahl, C. (2013, May 17). 1. Groei en ontwikkeling van het gelaat bij schisiskinderen. 2. De rol van de
orthodontist. Amsterdam, the Netherlands, Schisiscongresdag VUmc/ACTA.
Schulten, E.A.J.M. (2013, May 28). Reconstructie van de bovenkaak na tumorchirurgie: chirurgische en
prothetische mogelijkheden. Amsterdam, the Netherlands, 5e Implantologie à VU symposium. Een kwestie
van kiezen, Amstelzaal VUmc.
Tuinzing, D.B. (2013, May 24). Clinical demonstration. Paramaribo, Surinam, Klinische les afscheid dr. Orna.
Tuinzing, D.B. (2013, February 04). De sagittale splijtings osteotomie. Andere technieken, complicaties en
recidief. Leiden, the Netherlands, LUMC MKA.
Tuinzing, D.B. (2013, February 08). Een vlucht door de tijd. Chirurgische kaakcorrecties. Heerenveen, the
Netherlands, Afscheid dr. R.B. Greebe, Tjongerschans ziekenhuis.
Vehmeijer, M.J.J.B. (2013, May 31). Reconstructie onderrand kaak. Amsterdam, the Netherlands,
voorjaarsvergadering.
Wetselaar, P. (2013, March 22). Gebitsslijtage, multifactoriële oorzaak, lastige diagnostiek. Doorn, the
Netherlands, Congress Bijzondere Tandheelkunde, een lust en een last? Nederlandse Vereniging voor
Kindertandheelkunde (NVvK) & Vereniging teot Bevordering der Tandheelkundige Gezondheid voor
Gehandicapten (VBTGG).
Wetselaar, P. (2013, September 06). How to diagnose tooth wear patients. Eye, Amsterdam, the Netherlands,
ACTA-DE International Tooth Wear Congress: 4 clinical approaches 4 tooth wear.
Wetselaar, P. (2013, April 20). Interdisciplinaire samenwerking en het voordeel voor de patiënt. Ede, the
Netherlands, Congress Dutch Pain Society.
Wismeijer, D. (2013, June 21). Peri-implantitis; Een nieuwe ziekte? Ermelo, the Netherlands, 5th National
CAMLOG Congress.
Wismeijer, D. (2013, June 19). The treatment of peri-implantitis: What does the literature say? Houten, the
Netherlands, ITI Thema avond peri-implantitis.
Other professional functions
Baart, J.A.:
Bruggenkate, C.M. ten:
Lobbezoo, F.:
Lobbezoo, F.:
Member scientific advisory board Geneesmiddelen Bulletin (GeBu).
Chair Nederlandse ITI sectie.
Advisory board member ACTA Quality Practice.
Chairman The Netherlands Institute for Dental Sciences (IOT).
81
Wetselaar, P.:
Visscher, C.M.:
Member committee Tandarts Gnathologen Nederlandse Vereniging voor
Gnathologie en Prothetische Tandheelkunde.
Chair science committee Nederlandse Vereniging voor Orofaciale
Fysiotherapie (NVOF).
Courses organized for dental and medical professionals
More than 46 courses were given in the Netherlands for dentists, medical specialists and oral hygienists by the
following scientists:
A total of more than 30 courses were given by staff members of the dept. of Oral Radiology: W.E.R. Berkhout,
R.C. Hoogeveen, G.C.H. Sanderink and P.F. van der Stelt.
Disse, M. (2013, May 17). Organizer. Klinische avond: “Schisis een interdisciplinaire behandeling”: Amsterdam,
the Netherlands.
Goené, R.J. Implantologie: Het Fundament, NVOI, Putten, 22 & 23-03-2013
Goené, R.J. Implantologie voor praktijkmedewerkers, NVOI Jubileumcongres ,16/19-05-2013
Goené, R.J. Implantologie: Het Overzicht, NVOI, Utrecht 16-06-2013
Goené, R.J. Implantologie: Het Fundament, NVOI, Putten, 13/14-09-2013
Goené, R.J. Person to Person , Biomet/3i Tendenstandartsen, Amsterdam, Live surgery, 21-09-2013
Goené, R.J. Implantologie Integraal, NVOI, Putten, 4-10-2013
Goené, R.J. Implantologie De Verdieping, NVOI, Putten, 21 & 22-11-2013
Goené, R.J. Implantologie: Het Vervolg, NVOI, Putten, 13-12-2013
Koolstra, J.H. 12 April 2013, Opfriscursus Hoofd-Hals Anatomie
Koolstra, J.H. 28 March2013, Seminar Oral Anatomy
Koolstra, J.H. Langenbach, G.E.J., Korfage, J.A.M. & Ruijven L.J. van. April-May2013, Anatomie en Fysiologie
van het kauwstelsel voor Orthodontisten in opleiding.
Lobbezoo, F. Organizer, ACTA-QP-cursus “TMD-Doedag” (Amsterdam, March 2013).
Tahmaseb, A. 21-01-2013: Cadaver Course Rotterdam.
Visscher, C.M. Organizer, ACTA-QP-cursus “TMD-Doedag” (Amsterdam, March 2013).
Wismeijer, D. 21-11-2013. NVOI de verdieping. 1) Implantologie in een digitale omgeving.1 hr. 2) Bruggen op
implantaten 1 hr. 14 November.
Lectures given during courses for dental and medical professionals in the Netherlands
Aarab G. Slaapapnoe: red alerts en consequenties voor de dagelijkse praktijk. Contribution to ACTA-QP Course
“TMD-Doedag” (Amsterdam, 2 & 9 March 2013).
Aarab G. Workshop ‘TMD-functieonderzoek’. Contribution to ACTA-QP Course “TMD-Doedag” (Amsterdam, 2
& 9 March 2013).
Aarab G. Workshop ‘Vervaardigen wasindex & oefentherapie’. Contribution to ACTA-QP Course “TMDDoedag” (Amsterdam, 2 & 9 March 2013).
Attallah M.M. Workshop ‘TMD-functieonderzoek’. Contribution to ACTA-QP Course “TMD-Doedag”
(Amsterdam, 2 & 9 March 2013).
Attallah M.M. Workshop ‘Vervaardigen wasindex & oefentherapie’. Contribution to ACTA-QP Course “TMDDoedag” (Amsterdam, 2 & 9 March 2013).
Baart, J.A. Antibiotica en pijnstillers. Patiënten en hun pillen: the big four try out NVT-NVMKA-VMTI, ACTA
Amsterdam; 6 February 2013
Baart, J.A. Wilt u de mond focusvrij maken? QP oncologie ACTA Amsterdam, 2 February 2013
Baart, J.A. Mondziekten en kaakchirurgie voor huisartsen. VUmc Amsterdam; 7 February 2013
Baart, J.A. Kaakchirurgie bij kinderen. RAAK kinderartsen AMC-VUmc; 19 February 2013
Baart, J.A. Locale anesthesie voor assisterenden. Dental education ACTA/VUmc 7 March 2013
Baart, J.A. Uitbreiding dentogene ontstekingen, lokale anesthesie en extracties voor tropenartsen. VUmc
Amsterdam 14 March 2013
Baart, J.A. Beroep kaakchirurgie. Weekend academie Amsterdam, ’t Koggeschip Amsterdam, 16 March 2013
Baart, J.A. Locale anesthesie in de kaakchirurgie. Landdag AIOS-MKA, UMC Utrecht. 22 March 2013
Baart, J.A. Patiënten en hun pillen. Antibiotica en Pijnstillers. Themaproject 2013. The big four NVT, NVMKA,
VMTI. Nijmegen UMC Radboud, 27 March 2013
Baart, J.A. Medische situaties in de mondhygiënepraktijk. Pijnbestrijding tijdens en na de behandeling. Quality
Practice, ACTA dental education; 13 April 2013
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Baart, J.A. Atraumatisch extraheren en ridge preserveren. Obdam 5 April 2013
Baart, J.A. Koester je patiënten, ook als ze pillen gebruiken. Klinische avond, Leiderdorp; 9 April 2013
Baart, J.A. Antibiotica en pijnstillers. Patiënten en hun pillen: the big four try out NVT-NVMKA-VMTI, Den
Haag; 17 April 2013
Baart, J.A. Antibiotica en pijnstillers. Patiënten en hun pillen: the big four try out NVT-NVMKA-VMTI, VUmc
Amsterdam; 24 April 2013
Baart, J.A. Pain management during and after treatment. Russian society of dental hygienists. ACTA InHolland;
2-4 May 2013
Baart, J.A. De kaakchirurg in het schisisteam. Schisisdag ACTA dental education, Amsterdam; 17 May 2013
Baart, J.A. Autotransplantatie van een premolaar na een fronttrauma. QP ACTA; 28 September 2013
Baart, J.A. Weefselsparende kaakchirurgie. NVT/WTA Amsterdam; 4 okotber 2013
Baart, J.A. Autotransplantatie van een premolaar na een fronttrauma. QP ACTA; 12 October 2013
Baart, J.A. Radiologie: straling, diagnostiek en verantwoordelijkheden. QP ACTA; 2 November 2013
Baart, J.A. E-learning “pijnstilling in de tandartspraktijk” live online BSL; 19 november 2013
Baart, J.A. Wintersymposium. Aangezichtstrauma: epidemiologie en algemene principes. VUmc/ACTA; 13
December 2013
Baart, J.A. Schisisdag voor tandartsen. Kaakchirurgie bij schisiskinderen. ACTA-VUmc Amsterdam; 7 May 2013
Baart, J.A. Lokale anesthesie voor assisterenden. IJburg-tandheelkundig centrum Amsterdam; 17 May 2013
Baart, J.A. Lokale anesthesie voor assisterenden. Almaar 8 June 2013
Baart, J.A. Weefselsparende tandheelkunde. WTA-cursus. ACTA; 4 October 2013
Baart, J.A. Lokale anesthesie voor assisterenden. ACTA-VUmc; 7 November 2013
Forouzanfar, T. Bloedverdunners in de tandartspraktijk. Themaproject NVT-NVMKA-MTI, Alkmaar en
Maastricht 8 February and 2 May 2013
Forouzanfar, T. Pijnstillers in de tandartspraktijk. Themaproject NVT-NVMKA-MTI, Alkmaar en Maastricht 8
February and 2 May 2013
Goené, R.J. Atraumatisch extraheren en ridge preserveren. Obdam 5 April and 10 October 2013
Koutris M. Workshop ‘TMD-functieonderzoek’. Contribution to ACTA-QP Course “TMD-Doedag” (Amsterdam,
2 & 9 March 2013).
Koutris M. Workshop ‘Vervaardigen wasindex & oefentherapie’. Contribution to ACTA-QP Course “TMDDoedag” (Amsterdam, 2 & 9 March 2013).
Lobbezoo F. Oral Kinesiology. Contribution to ACTA Course “Dentistry for non-dentists” (Amsterdam, February
2013).
Lobbezoo F. Kauwen op bruxisme. Contribution to ACTA-QP Course “TMD-Doedag” (Amsterdam, 2 & 9 March
2013).
Lobbezoo F. Workshop ‘TMD-functieonderzoek’. Contribution to ACTA-QP Course “TMD-Doedag”
Lobbezoo F. Workshop ‘Vervaardigen wasindex & oefentherapie’. Contribution to ACTA-QP Course “TMDDoedag” (Amsterdam, 2 & 9 March 2013).
Lobbezoo F. All you need to know about pain! Bijdrage ACTA-DE Course “Pijn, een verwarrend dilemma”
(Amsterdam, March 2013).
Lobbezoo F. TMD-diagnostiek. Course for Oral Surgery Trainees AMC and VUmc (Amsterdam, March 2013).
Lobbezoo F. Pijn! Contribution to Symposium “Verwijspraktijk voor Endodontologie” (Haarlem, March 2013).
Lobbezoo F. Moderator WTA Spring Congress 2013 “Slaapstoornissen” (Amsterdam, April 2013).
Lobbezoo F. Pijn. Contribution to ACTA-DE Course “Endodontologie” (Amsterdam, juni 2013).
Lugt C.M.C. van der. Workshop ‘TMD-functieonderzoek’. Contribution to ACTA-QP Course “TMD-Doedag”
Lugt C.M.C. van der. Workshop ‘Vervaardigen wasindex & oefentherapie’. Contribution to ACTA-QP Course
Parvaneh H. Workshop ‘TMD-functieonderzoek’. Contribution to ACTA-QP Course “TMD-Doedag”
Parvaneh H. Workshop ‘Vervaardigen wasindex & oefentherapie’. Contribution to ACTA-QP Course “TMDDoedag” (Amsterdam, 2 & 9 March 2013).
Rollman A. Workshop ‘TMD-functieonderzoek’. Contribution to ACTA-QP Course “TMD-Doedag” (Amsterdam,
2 & 9 March 2013).
Rollman A. Workshop ‘Vervaardigen wasindex & oefentherapie’. Contribution to ACTA-QP Course “TMDDoedag” (Amsterdam, 2 & 9 March 2013).
Schulten, E.A.J.M. Reconstructie van kaakdefecten na chirurgische tumorbehandeling: chirurgische en
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prothetische mogelijkheden. Themadag Quality Practice: Mondafwijkingen - de rol van de tandarts. ACTA
26-01 and 02-02-13
Schulten, E.A.J.M. Reconstructie en dentale rehabilitatie na oncologische chirurgie. Nascholingscursus
Oncologie voor de Tandheelkundige Professie, ACTA 05-04-13
Schulten, E.A.J.M. Kaakreconstructies en implantaten. Voordracht tijdens KIO-cursus: Preprothetische en preimplantologische chirurgie en implantologie (11/12-04-2013), LUMC, Leiden. 12-04-13
Suijkerbuijk E.A. Workshop ‘TMD-functieonderzoek’. Contribution to ACTA-QP Course “TMD-Doedag”
Suijkerbuijk E.A. Workshop ‘Vervaardigen wasindex & oefentherapie’. Contribution to ACTA-QP Course “TMDDoedag” (Amsterdam, 2 & 9 March 2013).
Vervoorn-Vis G.M.G.J. Workshop ‘TMD-functieonderzoek’. Contribution to ACTA-QP Course “TMD-Doedag”
Vervoorn-Vis G.M.G.J. Workshop ‘Vervaardigen wasindex & oefentherapie’. Contribution to ACTA-QP Course
Visscher CM. Diagnostische overwegingen bij temporomandibulaire aandoeningen. Contribution to ACTA-QP
Course “TMD-Doedag” (Amsterdam, 2 & 9 March 2013).
Visscher C.M. Workshop ‘TMD-functieonderzoek’. Contribution to ACTA-QP Course “TMD-Doedag”
Visscher C.M. Workshop ‘Vervaardigen wasindex & oefentherapie’. Contribution to ACTA-QP Course “TMDDoedag” (Amsterdam, March 2013).
Warnsinck C.J. Workshop ‘T2 & 9 MD-functieonderzoek’. Contribution to ACTA-QP Course “TMD-Doedag”
Warnsinck C.J. Workshop ‘Vervaardigen wasindex & oefentherapie’. Contribution to ACTA-QP Course “TMDDoedag” (Amsterdam, 2 & 9 March 2013).
Wetselaar P. Slapen en slijten. Contribution to ACTA-QP Course “TMD-Doedag” (Amsterdam, March 2013)..
Wetselaar P. Workshop ‘TMD-functieonderzoek’. Contribution to ACTA-QP Course “TMD-Doedag”
Wetselaar P. Workshop ‘Vervaardigen wasindex & oefentherapie’. Contribution to ACTA-QP Course “TMDDoedag” (Amsterdam, 2 & 9 March 2013).
Wetselaar P. TMD-diagnostiek. Course for Oral Surgery Trainees (AMC and VUmc) (Amsterdam, March 2013).
Wetselaar P. Orale Kinesiologie. Course for study group Haarlem. (Overveen, December 2, 2013).
Wismeijer, D. 24-09-2013. Peri-implantitis: van Tandvlees naar implantaatvlees. Klinische avond paro praktijk
te Tilburg. 1hr.
Wismeijer, D. 14-11-2013. A car is not just a faster bicycle. Voordracht voor klinische avond praktijk voor
Implantologie Daan Kruger Nieuw Vennep. 1,5 hrs.
Tuinzing, D.B. ACTA Q Practice 19 January 2013. Het gezicht op het scherp van de snede 4x workshop 90 min.
Collaborations
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Albert Schweitzer Ziekenhuis, Afdeling dermatologie, dr. R. Laeijendekker.
AMOLF (Prof.dr. G. Koenderink), Amsterdam, NL.
Biofarmind, The Hague, the Netherlands
City University of New York (Dr.ir. S.C. Cowin), New York, USA.
Clinical Research Department (dkf) , University of Bern, Bern, Switzerland.
Crucell, Leiden, the Netherlands
Department of Clinical Epidemiology and Biostatistics, VUmc, Amsterdam
Department of Clinical Genetics, VUmc, Amsterdam
Department of Endocrinology, VUmc, Amsterdam
Department of life sciences, Inner Mongolia Agriculture University, Huhehot, China.
Department of MFP and Special Dental Care of the AMPHIA teaching hospital Breda (NL).
Department of Nuclear Medicine and PET research, VUmc, Amsterdam
Department of Nuclear Medicine and School of Dentistry, University of Nijmegen, the Netherlands: (Dr.
Otto Bormen and Prof. J. Jansen)
Department of Oral and Maxillofacial Surgery, Leids Universitair Medisch Centrum, Leiden
Department of Oral and Maxillofacial Surgery, Rijnland Ziekenhuis, Leiderdorp
Department of Oral Surgery , University of Bern, Bern, Switzerland. (Daniel Buser)
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Department of Product & Process Engineering, DelftChemTech, Delft University of Technology
Department of prothodontics , University of Bern, Bern, Switzerland. (Urs Braegger)
Department of prothodontics , University of Zurich, Zurich, Switzerland. (Fraukje Muller)
Department of restorative dentistry and biomaterial sciences. Harvard University, Boston USA (German
Gallucci)
Dipartimento di Medicina, Chirurgia e Odontoiatria – A.O. San Paolo, Università degli Studi di Milano.
Matteo Chiapasco / Paolo Cassentini
Dr ir H.A Reijers Eindhoven University of Technology, Den Dolech 2, PO Box 513, 5600 MB, The Netherlands
Ege University, Faculty of Medicine, Center for Brain Research & Department of Physiology, prof dr K.
Türker, Bornova, Izmir, Turkey.
Eindhoven University of Technology, Dept Materials Technology (Prof.dr.ir. J.M.J. den Toonder), Eindhoven,
NL.
Göttingen University (Prof.dr. C.F. Schmidt), Göttingen, Germany.
Grethe Jonasson; a) Research & Development Unit in Southern Älvsborg County, Sweden; b) Research
Center, Public Dental Service, Gothenburg, Sweden; c) Department of Orthodontics - Goteborg University,
Sweden.
Harvard University (Dr. R. Krishnan), Boston, USA.
Health Sciences University of Hokkaido, dr. M. Hashimoto, Hokkaido, Japan.
Hiroshima University, Dept Orthodontics (Prof.dr. Tanne, Dr. R. Sano), Hiroshima, Japan.
Hospital Hilversum (Dr. G.H.R. Albers), Hilversum, NL.
Hospital of Stomatology, Dental School of ZheJiang University, Huangzhou, China.
Institut für Anatomie, Zentrum für Experimentelle Medizin, Universitätsklinikum Hamburg-Eppendorf,
Hamburg, Germany
Katholieke Universiteit Leuven, Dept Biomechanics (Prof.dr. P. van Lenthe, Prof.dr. D. Vanderschueren),
Leuven, Belgium.
Katholieke Universiteit Leuven, Dept Physiology (Prof.dr. P. Hespel, Prof.dr. L. Deldicque, Prof.dr. S.
Boonen, Dr. R. Manders), Leuven, Belgium.
Katholieke Universiteit Leuven, Dept Rheumatology (Prof.dr F.P. Luyten, Prof.dr. P. Vanderschueren),
Leuven, Belgium.
Keele University (Prof.dr A. El Haj), Stoke-on-Trent, UK.
King Saud University, dr. Z. Salameh, Riyadh, Saudi Arabia.
Kyoto University (Prof.dr.ir T. Adachi, Dr. M. Tanaka), Kyoto, Japan.
Linköping University, Dept Clinical Experimental Medicine, Div Orthopaedics (Dr. A. Fahlgren), Linköping,
Sweden.
Linköping University, Dept Physics, Chemistry and Biology (Dr. E. Jager), Linköping, Sweden.
Netherlands Cancer Institute, Division of Immunology (Dr. Y. Xiao, Dr. J. Borst), Amsterdam, the
Netherlands.
Nordic Biosciences (Dr. K. Henriksen), Herlev, Denmark.
Okayama University (Prof.dr. H. Kamioka), Okayama, Japan.
Prof. ME Parker. Department of oral and maxillofacial radiology, University of Western Cape, South Africa.
Prof. R. Jacobs, Imaging Sciences, Katholieke Universiteit Leuven, Belgium.
Radboud University (Prof.dr. A.M. Kuijpers-Jagtman, Dr. R. van ‘t Hoff), Nijmegen, NL.
Radboud University (Prof.dr. J. Jansen and Dr. X.F. Walboomers), Nijmegen, NL.
Regensburg University Medical Center, Department of Prosthetic Dentistry, Prof. dr. M Behr, Regensburg,
Germany.
San Carlos University, Dept Physics, Cebu City (Prof.dr. R.G. Bacabac), Philippines.
Slotervaart General Hospital, Department of Clinical Neurophysiology and Brain Mapping Laboratory, dr
H.L. Hamburger, Amsterdam, The Netherlands.
Spaarne Hospital Heemstede (Dr. P.A. Nolte), Heemstede, NL.
Straumann AG, Basel Zwitserland. R Willie head of Prosthodontics
Technical University Eindhoven (Prof.dr. M. Rauterberg), Eindhoven, NL.
UMCG (Prof.dr. R.A. Bank), Groningen, NL.
Università degli Studi di Milano, Laboratory of Toxicology, DiSFeB (Prof.dr. E. Corsini), Milan, Italy
Universitair Medisch Centrum St. Radboud/Radboud Universiteit Nijmegen, Cariologie en Endodontologie,
prof. dr M.C.D.N.J.M. Huysmans.
Universiteit van Genève, Division of Cariology and Endodontology, prof. dr. I. Krejci, Genève, Swiss.
University at Buffalo, Department of Oral Diagnostic Sciences, dr. R. Ohrbach, Buffalo (NY), USA.
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University of Aberdeen (Prof.dr. M. Helfrich), Aberdeen, UK.
University of Alexandria, Dental Biomaterials, dr. M.N. Aboushelib, Alexandria, Egypt.
University of Cairo, Department of Operative Dentistry, dr. AA. El Zohairy, Cairo, Egypt
University of California San Francisco (Prof.dr. P. DenBesten), San Francisco, USA.
University of Connecticut (Dr. M. Musgrave), Connecticut, USA.
University of Groningen, Department of Prosthodontics, Prof dr M.C. Cune, Prof Dr H Meijer Groningen,
The Netherlands.
University of Helsinki (Prof.dr. K. Vaananen), Helsinki, Finland.
University of Helsinki, Department of Stomatognathic Physiology & Prosthetic Dentistry, dr J. Ahlberg,
Helsinki, Finland.
University of Hong Kong, Dept Oral Diagnosis and Polyclinics (Dr. T.K. Goto), Hong Kong, China.
University of Hull, Dept Engineering (Prof.dr. M. Fagan), Hull, Great Brittain.
University of Kiel (Prof.dr. P. Saftig), Kiel, Germany.
University of Madrid, (Prof.dr. R. Marco), Madrid, Spain.
University of Milan (Prof.dr. S. Bradamante), Milan, Italy.
University of Montreal. Faculty of Dentistry, prof dr Gilles Lavigne, Montreal, PQ, Canada.
University of Naples, Dept Orthodontics (Dr. I. Cioffi, Dr. M. Farella), Naples, Italy.
University of Navarra, School of Medicine (Prof.dr. J.F. Medina) , Pamplona, Spain.
University of Nijmegen, Department of Prosthodontics, dr C Kreulen Nijmegen, The Netherlands
University of Padova, TMD Clinic, dr D. Manfredini, Padova, Italy.
University of São Paulo State (UNESP), Department of Dental Materials and Prosthodontics, F. Trindade, LF
and Valandro, São Paulo, Brazil.
University of Stockholm (Prof.dr. G. Andersson), Stockholm, Sweden.
University of Sydney, Faculty of Dentistry, Jaw Function and Orofacial Pain Research Unit, prof dr Greg
Murray, Sydney, Australia.
University of Tanta, Department of Restorative Dentistry, dr. AI Abdalla, Tanta, Egypt.
University of Tennessee, Clinical Research Center, dr. F. Garcia Godoy, Memphis, USA.
University of Tokushima, Dept Orthodontics and Dentofacial Orthopedics (Prof.dr. E. Tanaka, Dr. N. Kawai),
Tokushima, Japan.
University of Turku, Department of Prosthetic Dentistry and Biomaterials research, Prof. dr. Pekka Vallittu,
Turku, Finland.
University of Umea (Prof.dr. U. Lerner), Umea, Sweden.
University of Umea, Faculty of Medicine, department of Clinical Oral Physiology, prof dr A. Wännman,
Umea, Sweden.
University of Zurich, Center for Dental and Oral Medicine, Dental Materials Unit, prof. dr. M. Özcan.
UTHSC Dental School, Department of Restorative Dentistry, S. Wendt, San Antonio, Texas, USA.
Utrecht University Medical Center (Prof.dr. W.J.A. Dhert, Prof.dr.ir. H. Weinans), Utrecht, NL.
Vrije Universiteit, Department of Clinical Neuropsychology, prof. dr. E.J.A. Scherder, Amsterdam, The
Netherlands.
Vrije Universiteit, Nederlands Tweelingen Register (NTR), prof. dr. D.I. Boomsma, Amsterdam, the
Netherlands.
VU Amsterdam, Dept Movement Sciences (Prof.dr. J. van Dieën, Prof.dr. A. de Haan, Dr. R. Jaspers, Dr. K.
Gerritsen), Amsterdam, NL.
VU Amsterdam, Dept Theoretical Physics (Prof.dr. F.C. MacKintosh, Prof.dr. G. Wuitte), Amsterdam, NL.
VU Amsterdam, Physics (Prof.dr. D. Iannuzzi), Amsterdam, NL.
Vumc, Afdeling dermatologie, dr. Th. Rustemeyer.
VUmc, Afdeling Pathologie, prof.dr. R.J. Scheper.
VUMC, Depr Physiology (Prof.dr V. van Hinsberg), Amsterdam, NL
VUMC, Dept Dermatology (Prof.dr R. Hoekzema), Amsterdam, NL
VUMC, Dept Endocrinology (Prof.dr. P. Lips, Dr. N. Bravenboer), Amsterdam, NL.
VUMC, Dept Orthopaedics (Prof.dr. B.J. van Royen, Dr. M.N. Helder, Prof.dr.ir. T.H. Smit), Amsterdam, NL.
VUMC, Dept Pathology (Dr. I. van Hoogstraten), Amsterdam, NL
VUMC, Dept Plastic Surgery (Dr. Frank Niessen), Amsterdam, NL
VUMC, Dept Plastic Surgery (Prof.dr. M. Ritt, Dr. M.G. Mullender), Amsterdam, NL.
VUMC, Dept Rheumatology (Prof.dr. W.F. Lems), Amsterdam, NL.
VUmc, Laboratorium voor klinische immunologie, dr. M. von Blomberg.
Zhejiang-California Nano Systems Institute, Hangzhou, China
Alharbi, NM. Printing bone substitutes. Supervisor: prof.dr. D. Wismeijer; co-supervisors: dr. A. Tahmaseb &
dr. Y. Liu, start: October 2012.
Apperloo, RC. Dental implants as anchorage for prostheses, number, configuration and suprastructure.
Supervisor: prof. dr. J. de Lange, start: June 2010.
Bastidas Coral, AP. Scaffold molding by CAD-CAM and targeting osteogenic differentiation of mesenchymal
stem cells by mechanical loading in a 3D environment: Implications for oral and maxillofacial bone defects.
Supervisors: prof.dr. J. Klein-Nulend, dr. C.J. Kleverlaan, dr. A.D. Bakker & dr. T. Forouzanfar, Start 2013.
Baas, EM. BSSO versus distraction osteogenesis of the mandible. Supervisor: prof.dr. J. de Lange, start: January
2007.
Beerens MW. White spot lesions after orthodontic treatment. Supervisor: prof.dr. J.M. ten Cate; cosupervisor: dr.ir. M.H. van der Veen, start: study in 2007, decision applying for PhD thesis in 2013.
Bergh, B van den. Epidemiology and treatment of mandibular trauma. Supervisor: dr. T. Forouzanfar, start:
2009.
Boink, MA. Histatin peptides for treatment of chronic wounds. Supervisors: prof.dr. E.C.I. Veerman and
prof.dr. S Gibbs; co-supervisor: dr. J.G.M. Bolscher, start: November 2010.
Bouwman, WF. Sinus floor elevation with bone and bone substitutes. Supervisors: prof.dr. C.M. ten
Bruggenkate and prof.dr. E.A.J.M. Schulten; co-supervisor: dr. N. Bravenboer, start 2008.
Bronoosh, P. Correlating cone beam computed tomography results with clinical findings of
temporomandibular disorders. Supervisor: prof.dr. P.F. van der Stelt, co-supervisor: prof.dr. F. Lobbezoo,
start: October 2012.
Buskermolen, JK. Tissue engineering gingiva for in vitro assays and risk assessment of dental materials.
Supervisor: prof.dr. S. Gibbs, start: June 2013.
Chen, C. Ceramic composite restorations. Supervisor: prof.dr. A.J. Feilzer; co-supervisor: dr. C.J. Kleverlaan,
start: November 2009.
Chen, H. Flow characteristics of the upper airway of patients with obstructive sleep hypopnea syndrome using
computational fluid dynamics and particle image velocimetry. Supervisors: prof.dr. P.F. van der Stelt,
prof.dr. F. Lobbezoo & prof.dr. J. de Lange; co-supervisor: dr. G. Aarab, start: November 2013.
Damaskos, S. The reliability an accuracy of Cone Beam Computed Tomography in detecting calcified
atheromatous lesions within the lumen of the internal carotid artery. Project leaders: dr. W.E.R. Berkhout
& dr. T. Forouzanfar
Chalil, S. Understanding muscle and bone anabolic resistance in ageing: is ER stress involved? Supervisor:
prof.dr. P. Hespel & prof.dr. J. Klein-Nulend; co-supervisors: dr. A.D. Bakker & dr. R. Manders, start: 2012.
Delwel, S. Oral health and orofacial pain in dementia. Supervisor: prof.dr. F. Lobbezoo, start: 2012.
Derksen, WBC. The full digital workflow in dental implant treatment. Supervisor: prof.dr. D. Wismeijer; cosupervisor: dr. A. Tahmaseb, start: 2013, ending 2016.
Esterik, FAS van. Bioresorbable materials for scaffolds in oral in oral regenerative medicine. Supervisors:
prof.dr. A.J. Feilzer, prof.dr. V. Everts and prof.dr. J. Klein Nulend; co-supervisors: dr. C.J. Kleverlaan, dr.
A.D. Bakker & dr.ir. R.F.M. van Oers, start: October 2012.
Fazaeli, S. Structure and function of the temporomandibular disc: new challenges for tissue engineering.
Supervisors: prof.dr. V. Everts & prof.dr.ir. T.H. Smit; co-supervisor: dr.ir. J.H. Koolstra, start: October 2011.
Fezari, S. Jaw joint. Supervisors: prof.dr. V. Everts and prof.dr.ir. T.H. Smit; co-supervisor: dr.ir. J.H. Koolstra,
start: 2012.
Glim, JE. The role of macrophages in myofibroblast differentiation. Supervisors: prof.dr. R.H.J. Beelen &
prof.dr. V. Everts; co-supervisors: dr. F.B. Niessen & dr. M. van Egmond, start: 2010.
Gooren, EE. Tissue engineering gingival for in vitro assays and risk assessment of dental materials. Supervisor:
prof.dr. S. Gibbs, start: November 2012.
Gregor, L. Low shrinkage dental composites. Supervisors: prof.dr A.J. Feilzer & prof.dr. I. Krejci, start:
September 2008.
Harkel ten, B. Comparison foreign body giant cells and osteoclasts. Supervisor: prof.dr. V. Everts; cosupervisor: dr.ir. T.J. de Vries, start: December 2011.
Hemmatian, H. Does the osteocyte lacuna affect bone adaptive response to aging? Supervisors: prof.dr. H. van
Lenthe and prof.dr. J. Klein-Nulend; co-supervisor: dr. A.D. Bakker.
Ibrahim, N. Value of Cone Beam CT in assessment of bone quality. Supervisor: prof.dr. P.F. van der Stelt; cosupervisor: dr. B.A. Hassan, start: September 2010.
87
Hoogeveen RC. Dose reduction in orthodontic radiography. Supervisor: prof.dr. P.F. van der Stelt; cosupervisors: dr. G.C.H. Sanderink & dr. W.E.R. Berkhout, start: 2012.
Jansen, DC. Osteoclast heterogeneity. Supervisor: prof.dr. V. Everts, co-supervisor: dr.ir. T.J. de Vries, start:
2010
Jaspers, GW. Medication in implant dentistry. Supervisor: prof.dr. J. de Lange, start: January 2011.
Jong, T de. Tissue engineering of the periodontal ligament. Supervisor: prof.dr.ir. T.H. Smit, start: November
2012.
Juffer, P. Biological pathways for regulation of muscle fiber size and bone mass. Supervisors: prof. dr. J. KleinNulend & prof. dr. P. Lips; co-supervisors: dr. A.D. Bakker &dr. R. Jaspers, start: January 2009.
Kaaij, NCW van der. The use of fluoride rinse for caries prevention during the orthodontic treatment with fixed
appliances, a randomized clinical trial. Supervisor: prof.dr. J.M. ten Cate; co-supervisor: dr.ir. M.H. van der
Veen, start: study in 2009, decision applying for PhD thesis in 2013.
Karssemakers, LHE. PET en SPEC scans in orofacial surgery. Supervisor: prof.dr. A.G. Becking, start: 2009.
Khashayar, G. The science of tooth color. Supervisor: prof.dr A.J. Feilzer; co-supervisor; dr. C.J. Kleverlaan,
start: October 2009.
Koutris, M. Effects of delayed-onset muscle soreness on the sensorimotor control of the masticatory system.
Supervisors: prof.dr.ir. M. Naeije & prof.dr. F. Lobbezoo; co-supervisor: dr. CM Visscher, start: 2007.
Kommers, SC. Etiology and treatment of malocclusion after trauma. Supervisor: dr. T. Forouzanfar, start: 2011.
Maningky, M.S. Implants in orofacial surgery. Supervisors: prof.dr. E.A.J.M Schulten & dr. T. Forouzanfar, start:
2012.
Martin, WJJM. Diagnostic and treatment modalities in orofacial pain. Supervisors: prof.dr. D.B. Tuinzing &
prof.dr. E.A.J.M. Schulten; co-supervisor: T. Forouzanfar, start: 2009.
Milheiro, A. Allergic reactions to dental nickel-containing appliances. Supervisor: prof.dr. A.J. Feilzer; cosupervisor: dr. C.J. Kleverlaan, start: April 2009.
Muris, J. Diagnostics of metal allergy associated with oral exposure. Supervisors: prof.dr. A.J. Feilzer & prof.dr.
R.J. Scheper, start: September 2005.
Muzalev, K. The relation between the type of bruxism and temporomandibular disorders. Supervisor: prof.dr.
F. Lobbezoo; co-supervisor: prof.dr.ir. M. Naeije, start: 2011.
Nolte, JW. Distraction osteogenesis in orofacial surgery. Supervisor: prof.dr. A.G. Becking, start: 2011.
Oomens, MAEM. Quality analysis of published research in maxillofacial surgery. Supervisor: dr. T. Forouzanfar,
start: 2009.
Ossendorp, R. Pain management after trauma surgery. Supervisor: dr. Forouzanfar & dr. F. Bloemen,start:
2011.
Overman, JR. Bone augmentation with autologous mesenchymal stem cells from adipose tissue, BMP-2, and
calcium phosphate carrier materials in the sinusfloor elevation model. Supervisors: prof.dr J. Klein-Nulend,
prof.dr. E.A.J.M. Schulten & prof.dr C.M. ten Bruggenkate; co-supervisor: dr. M.N. Helder, start: November
2008.
Parsa, A. Assessment of bone quality using CBCT; bone density. Supervisor: prof.dr. P.F. van der Stelt; cosupervisor: dr. B.A. Hassan, start: October 2010.
Pathak, JL. The etiology of generalized osteoporosis in rheumatoid arthritis. Supervisors: prof.dr J. KleinNulend & prof.dr. F.P. Luyten; co-supervisors: dr. A.D. Bakker & dr. N. Bravenboer, start: Ocober 2011.
Ramawadh, R.S. Molecular aspects of tissues around dental implants in oral oncology patients after
radiotherapy. Supervisors: prof.dr. E. Bloemena, prof.dr. E.A.J.M. Schulten & prof.dr. C.M. ten Bruggenkate;
co-supervisor: dr. N. Bravenboer. Start: 2011.
Renders, GAP. Consequences of mechanical interaction between cartilage and bone for development of
osteoarthrosis. Supervisor: prof.dr. V. Everts; co-supervisor: dr. G.E.J. Langenbach, start: September 2007.
Rhee, AK van der. Scaffold molding by CAD-CAM and targeting osteogenic differentiation of Mesenchymal
stem cells by mechanical loading in a 3D environment: Implications for oral and maxillofacial bone defects.
Supervisors: prof.dr. J. Klein-Nulend & dr. C.J. Kleverlaan; co-supervisors: dr. A.D. Bakker & dr. T.
Forouzanfar, start: October 2011; stopped in 2013.
Rollman, A. Chronic myogenous temporomandibular disorders: diagnostics, etiology and treatment.
Supervisor: prof.dr.ir. M. Naeije; co-supervisor: dr. C.M. Visscher, start: 2004.
Rozeboom, AVJ. Treatment of fractures of the condylar head. A randomized clinical trial. Supervisor: prof.dr. J.
de Lange, start: September 2011.
Ruiter MHT de. Surgical treatment options for OSAS. Supervisor: prof.dr. J. de Lange, start: October 2012.
Ruslin, M. Etiology of relapse after orthognatic surgery. Supervisor: prof.dr. D.B. Tuinzing; co-supervisor: dr. T.
Forouzanfar, start: 2011.
88
Rutten, S. Effect of low intensity ultrasound on established delayed non-union of the fibula, after a high tibial
osteotomy. Supervisors: prof.dr. J. Klein Nulend & prof.dr. P.I.J.M. Wuisman †; co-supervisor: dr. P.J. Nolte,
start: 2005.
Saatchi, A. Development and implementation of medical treatments for bone defects and bone disease.
Supervisors: prof.dr.ir. G. Amoabediny (Tehran, Iran) and prof.dr. J. Klein-Nulend; co-supervisors: dr. M.N.
Helder (VUmc) and dr. B. Zandieh Doulabi, start: 2013.
Salehi-Nik, S. Effects of surface modification and mechanical loading on the response of endothelial cells
loaded in biohybrid lung bioreactors. Supervisors: prof.dr.ir. G. Amoabediny (Tehran, Iran) and prof.dr. J.
Klein-Nulend; co-supervisor: dr. B. Zandieh Doulabi, start: 2012.
Salentijn, E. Epidemiology and treatment of mandibular trauma. Supervisor: dr. T. Forouzanfar, start: 2011.
Schimmel, M. Implants in geriatric patients. Supervisors: prof.dr. D. Wismeijer & prof.dr. F. Muller.
Scholtanus, JC. Bonding to carious dentin. Supervisor: prof.dr. A.J. Feilzer, start: April 2009.
Stoker, GT. BIOS-2 The Breda implant overdenture Study part two. Comparing three different treatment
modalities for implant supported overdentures. An eight year evaluation. Supervisors: prof.dr. D. Wismeijer
& prof.dr. M.A.J. van Waas, start: 2007.
Tabeian, H. Arthritis models for the Temporo Mandibular Joint. Supervisors: prof.dr. V. Everts & prof.dr. F.
Lobbezoo; co-supervisors: dr. A.D. Bakker & dr.ir. T.J. de Vries, start: 2012.
Tastepe, CS. Peri implant surface cleaning. Supervisor: prof.dr. D. Wismeijer; co-supervisors: dr. Y. Liu & dr. G.
Wu, start: April 2011.
Schimmel, M. Implants in Geriatric patients. Supervisors: prof.dr. D Wismeijer & prof.dr. F. Muller.
Tuijt, M. The role of muscle function on internal derangements of the TMJ. Supervisors: prof.dr.ir. M. Naeije &
prof.dr. F. Lobbezoo; co-supervisor: dr.ir. J.H. Koolstra, start: March 2007.
Velzen, FJJ. van Risk factors and complications in oral and maxillofacial implantology. Supervisors: prof.dr.
C.M. ten Bruggenkate & prof.dr. E.A.J.M. Schulten, start: 2010.
Verlinden, C.R.A. Compliance in orthognatic surgery. Supervisors: dr. T. Forouzanfar & prof.dr. D.B. Tuinzing.
Start: 2012.
Vermeer, AF. The effect of bisphosphonates on different osteoclast populations. Supervisor: prof.dr. V. Everts;
co-supervisor: dr.ir. T.J. de Vries, start: January 2010.
Vorselen, D. Mechanics at the (sub)-cellular level. Supervisors: prof.dr.ir. G.J.L. Wuite & prof.dr. V. Everts; cosupervisors: dr. J.J.W.A. van Loon & dr. W.H. Roos, start: June 2011.
Wang, D. Antimicrobial bone substitute – Incorporation of antibiotics into BioCP for treatment of bone loss
caused by peri-implantitis. Supervisor: prof.dr. D. Wismeijer; co-supervisor: dr. Y. Liu, start: November
2012.
Zande, MM van der. Digital dentistry in practice: On dentists’ interaction with technological transformation.
Supervisor: prof.dr. D. Wismeijer; co-supervisor: dr. R.C. Gorter, start: February 2012.
Zembic A. Overdentures on 2 implants in the maxilla. Supervisor: prof.dr. D. Wismeijer; co- supervisor: dr. A.
Tahmaseb. Start 2011, ending 2014/5.
Zygogiannis, K. Mini dental implants for overdentures in the edentulous mandible. Supervisor: prof.dr. D.
Wismeijer.
89
Education related research, including other research
Research on Dental Education
Associate dean of educational
research and development
Dr. J.M. Vervoorn
Education Institute
ACTA, Gustav Mahlerlaan 3004
1081 LA Amsterdam
Tel: +31-20-5980438
E-mail: [email protected]
Research objectives
In the ACTA faculty of Dentistry research is performed on several aspects of education in dentistry. This
includes research on the evaluation of courses within the curriculum, research on new teaching methods, such
as the Objective Structured Clinical Examination (OSCE), development and evaluation of a computer aided
digital teaching system creating a virtual learning environment including the application of haptics (the
Simodont Dental Trainer), the development of virtual teeth and jaws and comparison with biomedical
education elsewhere in Europe.
The input of academic personnel is limited to staff of the educational institute, and to some members of the
various departments. The research should not be considered as a separate programme; however it is intended
that this research will increase in the coming years.
Results
In 2013 further experiments have been carried out on training behaviour of students preparing for practical
examinations. It appeared that students who were in control of their training program and decided on their
own testing moments performed better than students that had to follow the test schedule of the faculty. The
possibility to collect data on training and testing behaviour in such a controlled environment offers the
opportunity to compare performance of various groups of students using similar exercises. For the use of a
virtual learning environment for dental students, virtual teeth have been developed. The created models
appear feasible for use in dental education and a useful learning asset in addition to human extracted teeth
and as a possible replacement of plastic teeth (Frasaco).
Research staff ACTA - OWI and other research (in full time equivalents)
Position
Staff members education
institute
PhD students
total 3rd funding
90
Name
Gorter, dr. R.C.
Vervoorn, dr. J.M.
Schoonheim-Klein, dr. M.E.
Bakker, drs. D.R.
Boer, drs. I.R. de
fte 2013
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0,10
0,15
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plan 2014
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0,10
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funding
guest
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Output
Bailey, S., Bullock, A., Cowpe, J., Barnes, E., Thomas, H., Thomas, R., Kavadella, A., Kossioni, A., KaraharjuSuvanto, T., Suomalainen, K., Kersten, H., Povel, E., Giles, M., Walmsley, A.D., Soboleva, U., Liepa, A. &
Akota, I. (2013). Core continuing professional development (CPD) topics for the European dentist.
European Journal of Dental Education, 17(1), e82-e87.
Boer, I.R. de, Wesselink, P.R. & Vervoorn, J.M. (2013). The creation of virtual teeth with and without tooth
pathology for a virtual learning environment in dental education. European Journal of Dental Education,
17(4), 191-197.
77(9), 1140-1146.
Bullock, A., Bailey, S., Cowpe, J., Barnes, E., Thomas, H., Thomas, R., Phillips, S., Kavadella, A., Kossioni, A.,
Tsiklakis, K., Karaharju-Suvanto, T., Suomalainen, K., Kersten, H., Povel, E., Giles, M., Walmsley, A.D.,
Soboleva, U., Liepa, A. & Akota, I. (2013). Continuing professional development systems and requirements
for graduate dentists in the EU: survey results from the DentCPD project. European Journal of Dental
Education, 17(1), e77-e87.
Kavadella, A., Kossioni, A.E., Tsiklakis, K., Cowpe, J., Bullock, A., Barnes, E., Bailey, S., Thomas, H., Thomas, R.,
Karaharju-Suvanto, T., Suomalainen, K., Kersten, H., Povel, E., Giles, M., Walmsley, D., Soboleva, U., Liepa,
A. & Akota, I. (2013). Recommendations for the development of e-modules for the continuing professional
development of European dentists. European Journal of Dental Education, 17(S1), 45-54.
Schoonheim-Klein, M., Gresnigt, C. & Velden, U. van der (2013). Influence of dental education in motivational
interviewing on the efficacy of interventions for smoking cessation. European Journal of Dental Education,
17(1), e28-e33.
Kossioni, A.E., Kavadella, A., Tzoutzas, I., Bakas, A., Tsiklakis, K., Bailey, S., Bullock, A., Cowpe, J., Barnes, E.,
Thomas, H., Thomas, R., Karaharju-Suvanto, T., Suomalainen, K., Kersten, H., Povel, E., Giles, M., Walmsley,
D., Soboleva, U., Liepa, A. & Akota, I. (2013). The development of an exemplar e-module for the continuing
professional development of European dentists. European Journal of Dental Education, 17(S1), 38-44.
Suomalainen, K., Karaharju-Suvanto, T., Bailey, S., Bullock, A., Cowpe, J., Barnes, E., Thomas, H., Thomas, R.,
Kavadella, A., Kossioni, A., Kersten, H., Povel, E., Giles, M., Walmsley, D., Soboleva, U., Liepa, A. & Akota, I.
(2013). Guidelines for the organisation of continuing professional development activities for the European
dentist. European Journal of Dental Education, 17(S1), 29-37.
Tokede, O., White, J., Stark, P.C., Vaderhobli, R., Walji, M.F., Ramoni, R., Schoonheim-Klein, M., Kimmes, N.,
Tavares, A. & Kalenderian, E. (2013). Assessing use of a standardized dental diagnostic terminology in an
electronic health record. Journal of Dental Education, 77(1), 24-36.
Tokede, O., Walji, M., Ramoni, R., White, J.M., Schoonheim-Klein, M., Kimmes, N.S., Vaderhobli, R., Stark, P.C.,
Patel, V.L. & Kalenderian, E. (2013). Treatment planning in dentistry using an electronic health record:
implications for undergraduate education. European Journal of Dental Education, 17(1), e34-e43.
Walji, M.F., Kalenderian, E., Tran, D., Kookal, K.K., Nguyen, V., Tokede, O., White, J.M., Vaderhobli, R., Ramoni,
R., Stark, P.C., Kimmes, N.S., Schoonheim-Klein, M.E. & Patel, V.L. (2013). Detection and characterization of
usability problems in structured data entry interfaces in dentistry. International Journal of Medical
Informatics, 82(2), 128-138.
Yekta, S.S., Lampert, F., Kazemi, S., Kazemi, R., Brand, H.S., Baart, J.A. & Mazandarani, M. (2013). Evaluation of
new injection and cavity preparation model in local anesthesia teaching. Journal of Dental Education, 77(1),
51-57.
exploration of barriers and incentives to adopting digital technologies. British Dental Journal, 215(11), E21.
Scientific publications ( non refereed)
Gottlieb, R., Buchanan, J. & Vervoorn, J.M. (2013). Simulation in dentistry and oral health. In A.L. Levine, S.
DeMaria Jr., A.D. Schwartz & A.J. Sim (Eds.), Comprehensive textbook of healthcare simulation (pp. 329340-21). New York: Springer Science + Business Media.
Akveld, N.A.E. (2013). Hoe krijgen we transparantie doorzichtig? Quality Practice. Nascholingstijdschrift voor
91
Boers, E. & Sanaan, B. (2013). Klachten tegen tandartsen. Nederlands Tandartsenblad, 68(1), 26-28.
Nijdam, H.J. (2013). Taakherschikking versus taakdelegatie in de cariologie. Quality
Wiegman, H. (2013). Het roer moet om. Nederlands Tandartsenblad, 68(2), 16-17.
Practice.
Schoonheim-Klein, M.E. NIH (2011-2016) in cooperation with Harvard, UCSF and Creighton US$ 100.000,- .
Wesselink, P.R., Ministry OCW € 800.000,-. Simodont project for three years 2008-2010. Extended till 2013 by
decision of OCW in October 2011.
Wismeijer, D. & Gorter R.C. International Team for Implantology (ITI): Digital dentistry in practice; on dentists’
Dentistry and Oral Implantology. February 2012 – December 2013: 110.000,- euro.
Invited speakers at (inter)national congresses or symposia
Crielaard, W. (2013, April 22). Genomics and the undergraduate dental curriculum. Glasgow, ABSTD and OMIG
Spring 2013 joint meeting.
Gorter, R.C. (2013, May 24). Tandarts en burnoutrisico: no time to change? Oostende, Belgium, Verbond van
Vlaamse Tandartsen.
Loveren, C. van (2013, July 03). Education of undergraduate dental students from ACTA in caries prevention.
Strijp, A.J.P. van (2013, July 03). Education of undergraduate dental students from ACTA in caries prevention.
Vervoorn, J.M. (2013, August 19). Implementation of new technologies in education, VR in particular.
Bangkok, Thailand, SEAADE.
Vervoorn, J.M. (2013, December 03). Virtual patients in dental education. Poznan, Poland, Conference on
Preclinical teaching in Dentistry, Poznan University of Medical Sciences.
Membership of international editorial boards
Gorter, R.C.:
Societal impact
The societal impact of the research and development is focused on the effect of learning behaviour on learning
outcomes and on the implementation of new technologies in education. This involves in particular the
research on a computer aided digital learning environment (the Simodont dental trainer).
MOOG inc. Development of the Simodont dental trainer.
Gorter, R.C. (9-2-2013). ACTA QP: MHG2 – Gedragsbeïnvloeding: kan ik het ook op een andere manier?
Other professional functions
Gorter, R. C.:
Gorter, R. C.:
Kamer Mondzorg – werkgroep 2. Richtlijnen Tandheelkunde. NMT (2013).
Bakker, DR.: Transfer of skills between virtual reality and reality in dental education. Supervisors: prof.dr. P.R.
Wesselink and dr. J.M. Vervoorn. Start 2010-11.
Boer de, IR.: Acceptance of new technologies in dental education. Supervisors: prof.dr. P.R. Wesselink and dr.
J.M. Vervoorn. Start 2010-11.
92
Appendix 2013
List of SCI journals, their impact factors and the number of ACTA publications in 2013 in each journal
Journal
IF
ACTA BIOMATER
ADV SPACE RES
AM J DENT
AM J EMERG MED
ANAL BIOCHEM
ANGLE ORTHOD
ANN ONCOL
ANN OTO RHINOL LARYN
ANN RHEUM DIS
ARCH ORAL BIOL
ARCH OTOLARYNGOL
ASTROBIOLOGY
BBA-BIOMEMBRANES
BEHAV THER
BIOCHIMIE
BIOCONGUJATE CHEM
BMC COMPLEM ALTERN M
BMC EVOL BIOL
BMC NEUROL
BMC PUBLIC HEALTH
BONE
BRIT DENT J
BRIT J ORAL MAX SURG
CALCIFIED TISSUE INT
CARIES RES
CLEFT PALATE-CRAN J
CLIN CANCER RES
CLIN J PAIN
CLIN ORAL IMPLAN RES
CLIN ORAL INVEST
CLIN ORTHOP RELAT R
COCHRANE DB SYST REV
COLLOID SURFACE B
COMMUNITY DENT ORAL
CONTACT DERMATITIS
DENT MATER
DENTOMAXILLOFAC RAD
DEV GROWTH DIFFER
DRUG SAFETY
ENVIRON SCI TECHNOL
EUR CELLS MATER
EUR J DENT EDUC
EUR J ORAL SCI
EUR J ORTHODONT
EUR J PAEDIATRIC DENT
EUR J PAIN
EUR PHYS JD
EUR SPINE J
FOOD CHEM
FUTURE ONCOL
GRANUL MATTER
HEALTH
HUM MOL GENET
IMMUNOBIOLOGY
IMMUNOTHERAPY
INT ENDOD J
INT J BIFURCAT CHAOS
INT J CANCER
INT J CARDIOL
INT J DATA MIN BIOIN
INT J DENT HYG
INT J MED INFORM
5,093
1,183
1,057
1,704
2,582
1,184
7,384
1,212
9,111
1,549
1,779
2,803
3,389
2,911
3,142
4,580
2,082
3,285
2,564
2,076
3,823
0,811
2,717
2,495
2,514
1,238
7,837
2,552
3,433
2,200
2,787
5,703
3,554
1,797
2,925
3,773
1,148
2,397
3,408
5,257
4,558
1,012
1,420
1,078
0,515
3,067
1,513
2,133
3,334
3,202
1,504
1,137
7,692
2,814
2,393
2,051
0,921
6,198
5,509
0,393
0,802
2,061
Number of
publications
1
1
2
1
1
1
1
1
1
1
2
2
1
1
1
1
1
1
1
1
5
4
4
1
3
1
1
1
4
3
1
3
1
1
1
2
6
1
1
1
1
8
5
1
1
1
1
1
2
1
1
1
1
1
1
2
1
1
1
1
3
1
Journal
IF
INT J ORAL MAX IMPL
INT J ORAL MAX SURG
INT J PAEDIATR DENT
INT UROGYNECOL J
J ADHES DENT
J ANXIETY DISORD
J BEHAV THER EXP PSY
J BIOMATER APPL
J BONE MINER RES
J CLIN PERIODONTOL
J CRANIOFAC SURG
J CRANIO MAXILL SURG
J DENT
J DENT EDUC
J DENT RES
J ENDODONT
J ESTHET RESTOR DENT
J IMMUNOL METHODS
J INNATE IMMUN
J NUCL MED
J NUTR BIOCHEM
J ORAL REHABIL
J OROFAC PAIN
J PAIN
J PERIODONTAL RES
J PERIODONTOL
J PROSTHODONT
J THORAC ONCOL
LANGMUIR
MATRIX BIOL
MEDIAT INFLAMM
MED ORAL PATOL
METHOD CELL BIOL
MICROGRAVITY SCI TEC
MOL BIOL EVOL
MOL ORAL MICROBIOL
NAT GENET
NEUROPHARMACOL
NEW ENGL J MED
ODONTOLOGY
ORAL DIS
ORAL ONCOL
ORAL SURG ORAL MED O
OSTEOARTHR CARTILAGE
PAIN
PAIN RES MANAG
PLOS ONE
PLOS PATHOG
P NATL ACAD SCI USA
QUINTESSENCE INT
RADIOTHER ONCOL
RES DEV DISABIL
SUPPORT CARE CANCER
SURG ENDOSC
TISSUE ENG PART A
TISSUE ENG PART B REV
TISSUE ENG PART C METH
TOXICOL APPL PHARM
TRANSPLANTATION
TRIALS
WORLD J MICROB BIOT
WOUND REPAIR REGEN
Total
1,908
1,521
0,924
2,169
0,905
2,524
2,381
2,640
6,128
3,688
0,686
1,610
3,200
0,989
3,826
2,929
0,957
2,225
4,458
5,774
4,552
2,344
2,387
3,240
1,990
2,398
0,681
4,473
4,187
3,190
3,882
1,017
1,444
0,500
10,353
2,648
35,209
4,114
51,658
1,576
2,377
2,695
1,495
4,262
5,644
1,042
3,730
8,136
9,737
0,710
4,520
2,483
2,649
3,427
4,065
4,065
4,065
3,975
3,781
2,206
1,262
2,757
Number of
publications
1
2
2
1
1
1
1
1
1
7
3
3
2
3
3
7
1
1
1
1
1
9
4
1
1
4
1
1
1
2
1
1
2
1
1
1
1
1
1
2
5
5
1
1
1
6
1
1
1
2
1
1
3
1
1
1
1
1
1
1
2
2
231
Name Index
Name
Page
Name
Page
Aarab, dr. G.
Aartman, dr. I.H.A.
Al Hothali, dds. M.M.
Al Kurwi, A.S.A.
Alfartousi, S.
Algera, dr. T.J.
Alharbi, dds.N.M.
Allard, mr.dr. R.H.B.
Alvarez Rodriquez, dds. E.
Anssari Moin, D.
Apperloo, drs. R.C.
Arikan, msc. M.
Ashton, dr. C.E.
Atallah, drs. M.M.
Baart, drs. J.A.
Baas, drs. E.M.
Baggen, drs. J.H.M.
Bakker, dr. A.D.
Bakker, drs. D.R.
Bastidas Coral, dds. A.P.
Becking, prof.dr. A.G.
Benzian, dds. H.
Bergh, drs. B. van den
Berkhout, dr. W.E.R.
Bikker, dr. F.J.
Bizzarro, dds.msc. S.
Blaauboer, drs. M.E.
Bloemena, prof.dr. E.
Boer, drs. I.R. de
Boink, msc. M.A.
Bolscher, dr. J.G.M.
Bonifacio, dr. C.C.
Bont, P. de
Bos, dr. A.
Bots, dr. C.P.
Boutsioukis, dr. C.
Bouwman, drs. W.F.
Brand, dr. H.S.
Brandt, dr. B.W.
Broers, drs. D.L.M.
Bronoosh, dds. P.
Brouns, drs. E.R.E.A.
Bruers, prof.dr. J.J.M.
Bruggeman, dr. J. P.
Bruggenkate, prof.dr. C.M. ten
Bruin, msc. B.J.Q. de
61
19
19
61
61
60
62
19
19
19
61
20
61
61
60
62
61
60
90
62
60
20
62
60
19
20
62
18
90
20
19
19
20
60
19
19
62
19
19
20
60
62
20
18
61
60
62
Bucci, drs. R.
Buskermolen, msc. J.K.
Byraki, drs. A.A.
Chalil, S.
Chen, dds. C.
Chen, dds. H.
Chin Jem Sen, drs. J.
Cukkemane, msc. N.
Dalen, dr. A., van
Damaskos, dr. S.
Dautovic, E.
Dekker, dr. J. den
Dekker, drs. H.
Delwel, drs. S.
Deng, dr. D.M.
Derksen, W.D.C.
Diaz-Serrano, dr. K.
Dicker, dr. G.J.F.M.
Diermen, dr. D.E. van
Dijk, drs. S., van
Dijk, msc. I.A., van
Disse, drs. M.A.
Donders, drs. H.C.M.
Dozic, dr. A.
Dubois, drs. L.
Duijster, drs. D.
Duyx, drs. M.P.M.A.
Eijkman, prof. dr. M.A.J.
Elmi, P.
Esterik, msc. F.A.S. van
Everts, prof.dr. V.
Fabels, L.N.J.
Faloni, drs. A.P.
Faure, drs. E.
Fazaeli, msc. S.
Feilzer, prof.dr. A.J.
Fernandez y Mostajo, msc. M.
Fernands, drs. G.
Fezari, S.
Forouzanfar, dr. T.
Gaalman, J.M.M.G.
Gambon, dr. D.L.
Geraets, dr. W.G.M.
Geurs, N.C.
Gibbs, prof.dr. S.
61
62
61
18
62
62
62
61
18
20
60
61
20
19
20
62
19
62
61
62
19
20
20
61
20
61
60
20
19
18
61
62
60
61
61
61
62
60
20
61
62
19, 60
61
19
60
20
60
94
Name
Page
Name
Page
Glim, J.E.
Goené, drs. R.J.
Gooren, msc. E.E.
Gorter dr. R.C.
Gorter, dr. R.C.
Graven, drs. K.M.L.
Gregor, dds. L.
Groot, M. de
Gunput, msc. S.T.G.
Guo, J.
Habets, dr. L.L.M.H.
Hansenova Manaskova, msc. S.
Harkel, msc. B. ten
Hassan, dr. B.A.
Haverman, msc. T.M.
Heijden, prof.dr.G. J.M.G. van der
Helmers, drs. R.
Hermus, R.R.
Hertog, drs. D.
Hoogeveen, msc. R.C.
Hove, R. van
Ibrahim, dds. N.
Imangaliyev msc. S.
Iskender, S.Y.
Jager, dr. D.H.J.
Jager, dr.ir. N., de
Janus, ir. M.M.
Jong, msc. B.G. de
Jong, msc. T. de
Jongh, prof.dr. A. de
Jong-Lenters, drs. M. de
Jongsma, dr. L.A.
Joosten, M.W.
Juffer, msc. P.
Kaaij, drs. N.C.W. van der
Kaiwar, A.
Kaman - van Zanten, ing. W.E.
Karagozoglu, drs. K.H.
Karssemakers, drs. L.H.E.
Khashayar, drs. G.
Klein Nulend, prof.dr. J.
Knibbe, drs. W.
Kommers, msc. S.C.
Koning, M.J.W.
Koolstra, dr.ir. J.H.
Koopman, drs. J.E
Korstjens, dr. C.M.
62
60
62
19
90
61
62
20
20
61
60
20
62
60
20
18
20
61
20
61
20
61
62
20
61
61
61
20
20
62
18
20
60
61
62
61
20
20
19
62
62
60
60
61
62
61
60
20
61
Koutris, drs. M.
Kramer, dr. G.J.C.
Krikken, drs. J.B.
Krom, dr. B.P.
Kuitert, dr. R.B.
Lagerweij, dr. M.D.
Laheij, drs. A.M.G.A.
Laine, dr. M.L.
Lange prof.dr. J. de
Langenbach, dr. G.E.J.
Liang, dds. Y.H.
Ligtenberg, dr. A.J.M.
Liu, dr. Y.
Liu, drs. T.
Lobbezoo, prof.dr. F.
Loos, prof.dr. B.G.
Louropoulou, dds. A.
Macedo, dds. R.G. de
Maningky, drs. M.S.
Marpaung, drs. C.M.
Martin, drs. W.J.J.M.
May, msc. A.
Metska, dds. M.E.
Mevissen-Renckens, E.H.M.
Milheiro, dds. A.
Moghimi, drs. M.
Moinzadeh, dds. A.T.M.
Muris, drs. J.
Muzalev, drs. K.
Naeije, prof.dr.ir. M.
Neelakantan, dds. P.
Nicu, dr. E.A.
Nolte, drs. J.W.
Noverraz, drs. R.L.M.
Oers, dr.ir. R.F.M. van
Oomens, drs. M.A.E.M.
Oosterhuis, M.
Ossendorp, R.
Overman, drs. J.R.
Özen, dr. B.
Özok, dr. A.R.
Papantonopoulos, dds. G.H.
Parsa, dds. A.
Parvaneh, drs. H.
Parys, K. van
60
61
20
19
60
19
20
19
18, 60
60
20
19
19, 60
60
62
60
61
18
20
18
20
62
61
62
20
20
20
62
19
20
20
62
62
60
20
19
62
61
60
62
61
63
63
19
19
20
63
61
61
95
Name
Page
Name
Page
Pathak, msc. J.L.
Persoon, msc. I.F.
Poorterman, dr. J.H.G.
Prahl, dr. C.
Prahl-Andersen, prof.dr. B.
Prins, dr. H-J.
Prodan, msc. A.
Raber-Durlacher, dr. J.E.
Rademacher, msc. W.M.H.
Ramawadh, msc. R.S.
Ramdat Missier, R.H.
Reijden, dr. W.A. van der
Renders, drs. G.A.P.
Reyes Sevilla, drs. M.
Rhee, msc. A.K. van der
Rijkschroeff, msc. P.
Roeters, prof.dr. F.J.M.
Rollman, mw. A.
Roos, C. de
Rozeboom, drs. A.V.J.
Rozema, prof.dr. F.R.
Ruiter, drs. M.H.T. de
Ruiz Zapata, A.M.
Ruslin, dds. M.
Rutten, S.
Salentijn, drs. E.
Sanderink, dr. G.C.H.
Scheerman, msc. J.F.M.
Scheres, dr. C.R.
Scholtanus, drs. J.C.
Schoonheim-Klein, dr. M.E.
Schreuder, W.H.
Selms, dr. M.K.A. van
Shemesh, dr. H.
Sijbrandij, drs. T.
Sleen, drs. J. van der
Slot, drs. D.E.
Sluis, dr. L.W.M. van der
Smeele, prof.dr. L.E.
Soet, dr. J.J. de
Steenbergen, dr. T.J.M. van
Stelt, prof.dr. P.F. van der
Stoker, drs.ir. G.T.
Suijkerbuijk, drs. E.
Tabassum, dr. A.
Tabeian, msc. H.
63
20
19
60
60
61
20
19
21
21
61
19
63
61
63
21
60
63
21
63
18
63
63
63
63
63
60
21
20
63
90
21
18, 60
60
19
21
21
21
20
18
19
19
60
63
19
62
62
63
Tahmaseb, dr. A.
Tastepe, dds. C.S.
Teeuw, msc. W.J.
Thymi, drs. M.
Tuijt, drs. M.
Tuinzing, prof.dr. D.B.
Tuk, J.C.
Uijlenbroek, drs. H.J.J.
Veen, dr.ir. M.H. van der
Veerbeek, H.J.
Velden, prof.dr. U. van der
Velzen, drs. F.J.J. van
Verheij, dr. H.G.C.
Vermeer, msc. A.F.
Vermeulen, F.M.J.
Verrips, prof.dr. G.H.W.
Verstraaten, mw. S.
Vervoorn, dr. J.M.
Vervoorn-Vis, drs. G.
Visscher, dr. C.M.
Vleugel, B. van der
Volgenant, drs. C.M.C.
Vorselen, msc D.
Vries, L. de
Waal, drs. S.V. van der
Waal, prof.dr. I. van der
Wang, dds. D.
Weijden, prof.dr. G.A. van der
Weijers, dr. M.
Wetselaar, drs. P.
Wezel. N.M. van
Wijk, dr. A.J. van
Willems, dr. N.M.B.K.
Wolff, dr. J.E.H.
Wu, dr. G.
Wu, dr. M.K.
Zande, msc. M.M. van der
Zandieh Doulabi, dr.ing. B.
Zaura, dr. E.
Zecha, drs. J.A.E.M.
Zembic, dds. A.
Zentner, prof.dr. A.
Zygogiannis, dds. K.
60
63
21
62
63
60
21
62
19
21
18
18
63
61
63
62
18
21
90
62
60
21
21
63
61
62
21
18
63
18
21
19, 90
62
62
19
62
60
62
61
19
21, 63
62
19
21
62
60
62
96

the academic centre for dentistry amsterdam

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