Help your child take control of Crohn`s or Ulcerative Colitis symptoms

Transcription

Help your child take control of Crohn`s or Ulcerative Colitis symptoms
Appointment
Prep Guide
Review this with your child
to make the most out of
your doctor visit.
Five ways to “connect” more:
1. Tell your story in 3 chapters:
• The past—give a quick “snapshot” of what your
condition has been like since your last
appointment.
• The present—describe what your symptoms
are like currently.
• The future—share specific treatment goals, like:
“I don’t want to miss out on school anymore
because I’m sick.”
2. Describe—don’t minimize—your symptoms.
Tell it like it is.
3. Talk about how you deal with your symptoms,
not just how you feel physically.
4. Review your current treatment—how it’s
working and any side effects you may be
experiencing.
5. Remember, connecting goes both ways—take
a pad to jot down notes during your visit.
See the
appointment
prep guide
inside...
For your kids with Crohn’s and
Ulcerative Colitis, learn more
about REMICADE®.
• REMICADE® has been shown to help kids with moderately to
severely active Crohn’s and ulcerative colitis who haven’t
responded well to other therapies achieve control over Crohn’s
and ulcerative colitis symptoms. Many children being treated
with REMICADE® also experience periods of no symptoms or
very few symptoms, or remission. Individual results may vary.
• After the first 3 treatments, children with Crohn’s and
ulcerative colitis need REMICADE® only once every 8 weeks.
That could be as few as 6 times a year. Treatment with
REMICADE® offers infrequent dosing that is customized based
on body weight. REMICADE® is given as a 2-hour IV infusion
by a healthcare professional.
Help your child
take control of
Crohn’s or
Ulcerative Colitis
symptoms
Ask your doctor about
REMICADE® today.
SELECTED Important SAFETY INFORMATION
Remicade® can lower your ability to fight infections.
Serious and sometimes fatal events can occur. There have been
reports of serious infections including tuberculosis (TB) and
infections caused by bacteria, fungi, or viruses that have spread
throughout the body. Lymphoma, including a fatal kind called
Hepatosplenic T-cell lymphoma, and other cancers have been
reported in children and adults taking Remicade®. Some people
with heart failure should not take Remicade®. Other serious
side effects reported include skin cancer, hepatitis B, liver injury,
blood problems, allergic reactions, nervous system problems,
or lupus-like syndrome. To learn more about these and other
risks, please read the Important Safety Information on pages
16–19 and the enclosed Medication Guide, and talk with
your doctor.
Visit www.remicade.com
and sign up for valuable
resources and support,
or call (877) 482-7840
for more information.
©Janssen Biotech, Inc. 2013
11/13
006099-131111
REMICADE® can reduce signs and symptoms and induce
and maintain clinical remission in pediatric patients six years
of age and older with moderately to severely active Crohn’s
disease and ulcerative colitis who haven’t responded well
to other therapies.
Are your child’s
symptoms under
control?
Your child’s symptoms can
interfere with his or her activities.
The symptoms of moderately to severely active Crohn’s disease
and ulcerative colitis can interrupt your child’s daily routine. If
your son or daughter is taking medication and still experiencing
symptoms, they may not be under control. You and your child
may have learned to live with your current treatment but you
don’t have to anymore—there are more options available.
What is Crohn’s Disease?
Crohn’s disease can cause inflammation anywhere in your
digestive tract and usually occurs in the lower part of the small
intestine or colon. Symptoms generally include stomach pain,
cramping, diarrhea, weight loss and fever.
What is Ulcerative Colitis?
Ulcerative colitis can cause inflammation in the colon or
large intestine. Symptoms generally include blood in the stool
or bloody diarrhea, frequent bowel movements, rectal bleeding,
stomach pain, cramping or weight loss.
SELECTED important SAFETY INFORMATION
Remicade® can lower your ability to fight infections.
Serious and sometimes fatal events can occur. There have been
reports of serious infections including tuberculosis (TB) and
infections caused by bacteria, fungi, or viruses that have spread
throughout the body. Lymphoma, including a fatal kind called
Hepatosplenic T-cell lymphoma, and other cancers have been
reported in children and adults taking Remicade®. Some people
with heart failure should not take Remicade®. Other serious side
effects reported include skin cancer, hepatitis B, liver injury,
blood problems, allergic reactions, nervous system problems,
or lupus-like syndrome. To learn more about these and other
risks, please read the Important Safety Information on pages
16–19 and the enclosed Medication Guide, and talk with
your doctor.
5
What are the available
treatments for kids
with Crohn’s and
Ulcerative Colitis?
Some of the medications used for adult patients are also used
to treat children. The medications fall into four main categories:
• 5-ASAs—such as Asacol®* (mesalamine) and Pentasa®*
(mesalamine)
• Steroids—such as prednisone and Entocort® EC* (budesonide)
• Immunosuppressants—such as Imuran®* (azathioprine) and
Purinethol®* (mercaptopurine)
• Biologic therapy—such as REMICADE® (infliximab)**
Only a doctor can determine which treatment is right for your
child, but it’s important that you understand the differences
between these medications and what they do.
*Indicated trademarks are registered trademarks of their respective owners.
**For moderately to severely active Crohn’s disease and ulcerative colitis in
patients six years of age and older.
SELECTED Important SAFETY INFORMATION
Remicade® can lower your ability to fight infections. Serious
and sometimes fatal events can occur. There have been reports
of serious infections including tuberculosis (TB) and infections
caused by bacteria, fungi, or viruses that have spread
throughout the body. Lymphoma, including a fatal kind called
Hepatosplenic T-cell lymphoma, and other cancers have been
5-ASAs
Can reduce inflammation
and help prevent flare-ups,
e.g., Asacol®* (mesalamine)
Pentasa®* (mesalamine)
Steroids
Most often used
short-term to reduce
inflammation in patients
who have not responded
well to 5-ASAs, e.g.,
prednisone, Entocort®
EC* (budesonide)
Immunosuppressants
Can be used to induce and
maintain remission and
decrease the need for
steroids, e.g., Imuran®*
(azathioprine), and
Purinethol®* (mercaptopurine)
Biologic
Used to induce and maintain
remission when other
therapies have failed to
control symptoms.
reported in children and adults taking Remicade®. Some people
with heart failure should not take Remicade®. Other serious side
effects reported include skin cancer, hepatitis B, liver injury, blood
problems, allergic reactions, nervous system problems, or
lupus-like syndrome. To learn more about these and other risks,
please read the Important Safety Information on pages 16–19
and the enclosed Medication Guide, and talk with your doctor.
7
Remicade®(infliximab)
is a biologic
What is REMICADE® and
how does it work?
REMICADE® is an advanced treatment that works differently
from conventional medications. It’s a protein that blocks a
substance called TNF-alpha, which can cause inflammation.
REMICADE® helps control this underlying cause of inflammation.
What is the treatment like?
The treatment process is straightforward. Your doctor may decide
to give your child medicine before starting the REMICADE®
infusion to prevent or lessen side effects. An IV needle will be
placed in your child’s arm or hand by a healthcare professional
and REMICADE® will be infused directly into the bloodstream so it
can get to work. Treatment takes about two hours, during which
your child can read, watch TV, do quiet work, or just relax while
accompanied by a nurse.
A healthcare professional will monitor your child during the
Remicade® infusion and for a period of time afterward for side
effects. Your doctor may do certain tests while your child is taking
Remicade® to monitor for side effects and to see how well your
child responds to the treatment. After the first three doses, your
child will need to receive REMICADE® only once every eight
weeks. That could be as few as six times a year.
Is REMICADE® right for your child?
REMICADE® is not for everyone; only your child’s doctor can
decide if REMICADE® is right for your child. REMICADE®, like other
medicines that affect your immune system, is a strong medicine
that can cause serious side effects.
SELECTED important SAFETY INFORMATION
Remicade® can lower your ability to fight infections.
Serious and sometimes fatal events can occur. There have been
reports of serious infections including tuberculosis (TB) and
infections caused by bacteria, fungi, or viruses that have spread
throughout the body. Lymphoma, including a fatal kind called
Hepatosplenic T-cell lymphoma, and other cancers have been
reported in children and adults taking Remicade®. Some people
with heart failure should not take Remicade®. Other serious side
effects reported include skin cancer, hepatitis B, liver injury,
blood problems, allergic reactions, nervous system problems,
or lupus-like syndrome. To learn more about these and other
risks, please read the Important Safety Information on pages
16–19 and the enclosed Medication Guide, and talk with
your doctor.
9
REMICADE (infliximab)
has been shown to
make a difference*
®
What has REMICADE® been
proven to do for a child with
Crohn’s or UC?
In a year-long clinical study, many kids with Crohn’s disease or
UC who began treatment with REMICADE® experienced:
• Rapid symptom improvement, or “response” (at Week 8
for ulcerative colitis and Week 10 for Crohn’s disease)
• Periods of no symptoms or very few symptoms, or
clinical remission at one year
• Possible elimination of steroid use for Crohn’s in some patients
*Individual results may vary. REMICADE® is not for everyone.
Only a doctor can decide if REMICADE® is right for your child.
Please discuss any questions related to symptoms or treatment
with your doctor.
SELECTED important SAFETY INFORMATION
Remicade® can lower your ability to fight infections.
Serious and sometimes fatal events can occur. There have been
reports of serious infections including tuberculosis (TB) and
infections caused by bacteria, fungi, or viruses that have spread
throughout the body. Lymphoma, including a fatal kind called
Hepatosplenic T-cell lymphoma, and other cancers have been
reported in children and adults taking Remicade®. Some people
with heart failure should not take Remicade®. Other serious side
effects reported include skin cancer, hepatitis B, liver injury,
blood problems, allergic reactions, nervous system problems,
or lupus-like syndrome. To learn more about these and other
risks, please read the Important Safety Information on pages
16–19 and the enclosed Medication Guide, and talk with
your doctor.
11
Crohn’s findings:
In a study of 112 patients, almost 9 out of 10 (88%) children
experienced symptom improvement soon (Week 10) after starting
treatment with REMICADE®.
Ulcerative Colitis findings:
In 44 out of 60 patients (73%), children experienced symptom
improvement soon (Week 8) after starting treatment with
REMICADE®.
REMICADE® has been shown
to improve symptom control
for children with Crohn’s and
Ulcerative Colitis.
If your son or daughter is still coping with symptoms of
moderately to severely active Crohn’s disease or ulcerative
colitis and they experience flare-ups more than two times per
year despite treatment with other therapies, the disease may
not be as under control as it could be.
REMICADE® may help reduce your child’s painful and
unpredictable symptoms. That’s when you know your
child’s Crohn’s or ulcerative colitis symptoms are under control.
SELECTED Important SAFETY INFORMATION
Remicade® can lower your ability to fight infections. Serious
and sometimes fatal events can occur. There have been reports
of serious infections including tuberculosis (TB) and infections
caused by bacteria, fungi, or viruses that have spread
throughout the body. Lymphoma, including a fatal kind called
Hepatosplenic T-cell lymphoma, and other cancers have been
reported in children and adults taking Remicade®. Some people
with heart failure should not take Remicade®. Other serious side
effects reported include skin cancer, hepatitis B, liver injury, blood
problems, allergic reactions, nervous system problems, or
lupus-like syndrome. To learn more about these and other risks,
please read the Important Safety Information on pages 16–19
and the enclosed Medication Guide, and talk with your doctor.
13
Help your child take
the first step
In a 54-week study for Crohn’s
and a 54-week study for
ulcerative colitis, children had
a reduction in signs and
symptoms and achieved
symptom remission.
REMICADE® (infliximab) is not a steroid.
Some children taking REMICADE® for Crohn’s disease were able
to achieve remission of symptoms. In fact, 46% of kids with
Crohn’s taking steroids at the beginning of the study who
received REMICADE® every 8 weeks were able to stop taking
steroids while in remission by the end of the study. Individual
results may vary.
But remember: only your child’s doctor can decide if reducing
or stopping steroids is appropriate. Like other medicines
that affect your child’s immune system, REMICADE® can also
cause serious side effects.
Some children taking REMICADE® for ulcerative colitis were
also able to achieve remission of symptoms. In fact, 24 out of
60 (40%) of kids with ulcerative colitis who received REMICADE®
experienced symptom remission at Week 8 during the study.
Only your child’s gastroenterologist can determine if the
benefits of treatment with REMICADE® outweigh the potential
risks and side effects.
Today, you can help your child take the first step toward
control of his or her symptoms.
SELECTED Important SAFETY INFORMATION
Remicade® can lower your ability to fight infections.
Serious and sometimes fatal events can occur. There have
been reports of serious infections including tuberculosis
(TB) and infections caused by bacteria, fungi, or viruses that
have spread throughout the body. Lymphoma, including a
fatal kind called Hepatosplenic T-cell lymphoma, and other
cancers have been reported in children and adults taking
Remicade®. Some people with heart failure should not take
Remicade®. Other serious side effects reported include skin
cancer, hepatitis B, liver injury, blood problems, allergic
reactions, nervous system problems, or lupus-like syndrome.
To learn more about these and other risks, please read the
Important Safety Information on pages 16–19 and the
enclosed Medication Guide, and talk with your doctor.
15
Important Safety Information
to discuss with your child’s
doctor.
Only your doctor can recommend a course of treatment
after checking your health condition.
REMICADE® (infliximab) can cause serious side effects such
as lowering your ability to fight infections.
Some patients, especially those 65 years and older, have
had serious infections caused by viruses, fungi, or bacteria
that have spread throughout the body, including
tuberculosis (TB) and histoplasmosis. Some of these
infections have been fatal. Your doctor should monitor
you closely for signs and symptoms of TB during
treatment with REMICADE®.
Unusual cancers have been reported in children and
teenage patients taking TNF-blocker medicines.
Hepatosplenic T-cell lymphoma, a rare form of fatal
lymphoma, has occurred mostly in teenage or young
adult males with Crohn’s disease or ulcerative colitis
who were taking REMICADE® and azathioprine or
6-mercaptopurine. For children and adults taking TNF
blockers, including REMICADE®, the chances of getting
lymphoma or other cancers may increase.
You should discuss any concerns about your health and
medical care with your doctor.
What should I tell my doctor before I take REMICADE®?
You should let your doctor know if you have or ever had any of
the following:
• Tuberculosis (TB) or have been near someone who has TB. Your
doctor will check you for TB with a skin test. If you have latent
(inactive) TB, you will begin TB treatment before you start
REMICADE®.
• Lived in a region where certain fungal infections like
histoplasmosis or coccidioidomycosis are common.
• Infections that keep coming back, have diabetes or an immune
system problem.
• Any type of cancer or a risk factor for developing cancer, for
example, chronic obstructive pulmonary disease (COPD) or had
phototherapy for psoriasis.
• Heart failure or any heart condition. Many people with
heart failure should not take REMICADE®.
• Hepatitis B virus (HBV) infection or think you may be a carrier of
HBV. Your doctor will test you for HBV.
• Nervous system disorders (like multiple sclerosis or
Guillain-Barré syndrome).
Also tell your doctor if you:
• Use the medicines Kineret (anakinra), Orencia (abatacept)
or Actemra (tocilizumab) or other medicines called
biologics used to treat the same problems as REMICADE®.
•A
re pregnant, plan to become pregnant, are breastfeeding, or have a baby and were using REMICADE®
during your pregnancy. Tell your baby’s doctor about
your REMICADE® use before the baby receives any vaccine
because of an increased risk of infection for up to 6 months
after your last dose of REMICADE® you received during
your pregnancy.
• Recently received or are scheduled to receive a vaccine.
Adults and children taking REMICADE® should not receive
live vaccines or treatment with a weakened bacteria (such
as BCG for bladder cancer) while taking REMICADE®.
17
What should I watch for and talk to my doctor about
before or while taking REMICADE®?
The following serious (sometimes fatal) side effects have
been reported in people taking REMICADE®.
You should tell your doctor right away if you have any
of the signs listed below:
• Infections (like TB, blood infections, pneumonia)—
fever, tiredness, cough, flu, or warm, red or painful skin or
any open sores. REMICADE® can make you more likely to
get an infection or make any infection that
you have worse.
• Lymphoma, or any other cancers in adults and children.
• Skin cancer—any changes in or growths on your skin.
• Heart failure—new or worsening symptoms, such as
shortness of breath, swelling of your ankles or feet, or
sudden weight gain.
• Liver injury—jaundice (yellow skin and eyes), dark brown urine,
right-sided abdominal pain, fever, or severe tiredness.
• Blood disorders—fever that doesn’t go away, bruising,
bleeding, or severe paleness.
• Nervous system disorders—numbness, weakness, tingling,
changes in your vision, or seizures.
• Allergic reactions during or after the infusion—hives, difficulty
breathing, chest pain, high or low blood pressure, swelling of
face and hands, and fever or chills.
• Lupus-like syndrome—chest discomfort or pain that does not
go away, shortness of breath, joint pain, rash on the cheeks or
arms that gets worse in the sun. The more common side effects
with REMICADE® are respiratory infections (that may include
sinus infections and sore throat), headache, rash, coughing,
and stomach pain.
• Psoriasis—new or worsening psoriasis such as red scaly patches
or raised bumps on the skin that are filled with pus.
005912-131106
• Reactivation of HBV—feeling unwell, poor appetite,
tiredness, fever, skin rash, and/or joint pain.
Please read the accompanying Medication Guide for
REMICADE®, and discuss it with your doctor.
You are encouraged to report negative side effects of
prescription drugs to the FDA. Visit www.fda.gov/medwatch
or call 1-800-FDA-1088.
19
Frequently asked
questions
Q What is the goal of treating
pediatric Crohn’s disease
or Ulcerative Colitis with
REMICADE®?
A The goal is to go beyond temporary relief of symptoms
to achieve Crohn’s and ulcerative colitis symptom remission,
and to reduce or stop the need for steroids for children
with Crohn’s.
Q Is REMICADE® right for
my child?
A R EMICADE can lower your ability to fight infections.
®
Serious and sometimes fatal events can occur. There have
been reports of serious infections including tuberculosis (TB)
and infections caused by bacteria, fungi, or viruses that have
spread throughout the body. Lymphoma, including a fatal
kind called Hepatosplenic T-cell lymphoma, and other
cancers have been reported in children and adults taking
REMICADE®. Some people with heart failure should not take
REMICADE®. Other serious side effects include hepatitis B,
liver injury, blood problems, allergic reactions, nervous
system problems, or lupus-like syndrome. To learn more
about these and other risks, please read the Important
Safety Information on pages 16–19 and the enclosed
Medication Guide, and talk with your doctor.
21
Q How is REMICADE®
administered and how often
will my child have to take it?
A R EMICADE is given as an intravenous infusion by a
®
healthcare professional, and administration takes at least
two hours. After the first three doses, your child will remain
on maintenance therapy, which is just once every eight
weeks. That could be as few as six times a year.
Q What should I know about
side effects?
A R EMICADE , like other medicines that affect your immune
®
system, is a strong medicine that can cause serious side
effects such as cancer and serious infections caused by
viruses, fungi or bacteria that have spread throughout the
body, including tuberculosis (TB) and histoplasmosis. Some
of these side effects have been fatal. For more information
about these and other serious side effects, please read the
Important Safety Information on pages 16–19 and the
accompanying Medication Guide for REMICADE®, and
discuss them with your child’s doctor. The most common
side effects of REMICADE® are mild and manageable, and
include: respiratory infections, headache, rash, coughing,
and stomach pain.
Q What should I watch for?
A You should discuss any questions or concerns about your
child’s health with your child’s doctor. On pages 16–19,
please read the Important Safety Information. You will also
find an accompanying Medication Guide for REMICADE®
that includes the most common and the most serious side
effects, related symptoms and when to talk to your child’s
doctor or seek medical care. If you seek medical care for
your child from a healthcare professional other than the
doctor who prescribed REMICADE®, it is important to let
him or her know about your child’s medical history and any
current medications, including REMICADE®.
Q Is REMICADE® covered
by insurance?
A R EMICADE is covered by most commercial insurance
®
plans. Coverage policies may vary by insurer, or even
between plans offered by the same insurer. If you
have any questions about insurance coverage or
reimbursement, you should first call your insurance
company. If you need additional information or patient
assistance for REMICADE®, please call AccessOne® at
(888) ACCESS-1 (888-222-3771), Monday through Friday,
8:00 AM to 8:00 PM, E.T.
Please read the Important Safety Information for
REMICADE®, included on pages 16–19, and discuss it
with your child’s doctor.
23
You can help
your child and
your family
•R
EMICADE® Patient Stories
Visit www.ulcerativecolitisstories.com or
www.crohnsdiseasestories.com to explore stories of people who
have found control from their symptoms.
How else can you help your
child live with Crohn’s or
ulcerative colitis symptoms?
• AccessOne® personal Care Coordinators are available to help
answer questions about insurance coverage, provide you with
additional educational materials, and assist you with
appointment reminders and follow-up calls. They can also
provide information about infusion sites that may be
convenient to your home or your child’s school.
Dealing with the symptoms of Crohn’s or ulcerative colitis
can be particularly difficult for a child. But you can make a
difference. In addition to providing love and support, the
most significant way in which you can help your child is to
learn as much as possible about the disease and available
treatment options. The following resources can help you
help your child, and your whole family learn more:
Other resources:
Resources from the makers of Remicade®:
•R
emiStart®
If you have difficulty affording the medication out-of-pocket
costs of treatment for your child, you may be eligible for
financial assistance through the RemiStart® program. To find
out more visit www.RemiStart.com.
• Crohn’s and Colitis Foundation of America (CCFA)
www.ccfa.org—provides a wide variety of information
on Crohn’s disease, ulcerative colitis, support groups,
education programs, events, social programs for kids with
Crohn’s and ulcerative colitis, links to info on current research,
and much more.
• REMICADE.com includes information about Crohn’s
disease, ulcerative colitis, REMICADE® (infliximab) and
how it works, as well as a listing of related books.
• North American Society for Pediatric Gastroenterology,
Hepatology and Nutrition (NASPGHAN)
www.naspghan.org provides education and assistance
with locating doctors, etc.
SELECTED Important SAFETY INFORMATION
Remicade® can lower your ability to fight infections.
Serious and sometimes fatal events can occur. There have
been reports of serious infections including tuberculosis
(TB) and infections caused by bacteria, fungi, or viruses that
have spread throughout the body. Lymphoma, including a
fatal kind called Hepatosplenic T-cell lymphoma, and other
cancers have been reported in children and adults taking
Remicade®. Some people with heart failure should not take
Remicade®. Other serious side effects reported include skin
cancer, hepatitis B, liver injury, blood problems, allergic
reactions, nervous system problems, or lupus-like syndrome.
To learn more about these and other risks, please read the
Important Safety Information on pages 16–19 and the
enclosed Medication Guide, and talk with your doctor.
25
Information for
kids & teens
The real deal on Crohn’s and
Ulcerative Colitis.
Having Crohn’s or ulcerative colitis (UC) doesn’t mean you have
to always worry about having symptoms. You can feel better and
that can help you do more of the things you want to do. The
important thing to remember is to be open and honest, and to
discuss how you’re feeling with your parents and your doctor.
They want to know how your symptoms are affecting your life
so they can help find the best care and treatment for you.
It can also be helpful to let other adults like your teachers and
the school nurse know you have Crohn’s or UC. That way, they’ll
be prepared to understand and support you when you’re not
feeling well.
REMICADE® may be able to help you get control over
Crohn’s or UC symptoms. Individual results may vary.
SELECTED important SAFETY INFORMATION
Remicade® can lower your ability to fight infections.
Serious and sometimes fatal events can occur. There have been
reports of serious infections including tuberculosis (TB) and
infections caused by bacteria, fungi, or viruses that have spread
throughout the body. Lymphoma, including a fatal kind called
Hepatosplenic T-cell lymphoma, and other cancers have been
reported in children and adults taking Remicade®. Some people
with heart failure should not take Remicade®. Other serious side
effects reported include skin cancer, hepatitis B, liver injury,
blood problems, allergic reactions, nervous system problems,
or lupus-like syndrome. To learn more about these and other
risks, please read the Important Safety Information on pages
16–19 and the enclosed Medication Guide, and talk with
your doctor.
27
So what is
REMICADE®(infliximab)?
REMICADE® is a type of medicine that works by blocking a
protein in your body that causes inflammation in your intestines.
The inflammation causes diarrhea, stomach pain and fever, and
you may also feel tired. REMICADE® helps reduce this inflammation.
How will you receive Remicade®?
Only a doctor or nurse can give you REMICADE®. That means you
go to your doctor’s office or a place called an infusion center to
get it. Your doctor may decide to give you medicine before
starting the infusion to prevent or lessen side effects. They’ll hook
up an IV infusion to your arm or hand and let the medicine drip
in for two hours, kind of like you’ve seen on TV.
Yeah, we know it’s kind of unusual to get medicine through an
IV, but there’s a very good reason for it. When medicine
is infused, it goes straight into your bloodstream and gets
to work. Getting an infusion may seem weird at first, but you’ll
have someone nearby during the infusion.
o view a video on how REMICADE® works, scan the
T
code or visit the sites www.crohnsdiseasestories.com
(for Crohn’s) or www.ulcerativecolitisstories.com
(for UC) and click on “The Science of REMICADE®“
SELECTED important SAFETY INFORMATION
Remicade® can lower your ability to fight infections.
Serious and sometimes fatal events can occur. There have been
reports of serious infections including tuberculosis (TB) and
infections caused by bacteria, fungi, or viruses that have spread
throughout the body. Lymphoma, including a fatal kind called
Hepatosplenic T-cell lymphoma, and other cancers have been
reported in children and adults taking Remicade®. Some people
with heart failure should not take Remicade®. Other serious side
effects reported include skin cancer, hepatitis B, liver injury,
blood problems, allergic reactions, nervous system problems,
or lupus-like syndrome. To learn more about these and other
risks, please read the Important Safety Information on
pages 16–19 and the enclosed Medication Guide, and talk
with your doctor.
29
What should you wear to the infusion?
If you want to tell your mom or dad that you need a new outfit
for the infusion, we won’t say a word. But really, all you need
are some comfortable clothes. Your infusion with REMICADE®
will take about 2 hours, so during this time you can kick back,
relax, listen to the latest tunes, even do a little school work (no
getting out of that).
How often do you have to go for infusions?
After the first three doses, you will only have to receive
REMICADE® (infliximab) every 8 weeks, or about every 2
months, or as few as 6 times a year. (Yeah, we know, they’re all
the same…just wanted to see if you were paying attention.)
SELECTED Important SAFETY INFORMATION
Remicade® can lower your ability to fight infections. Serious
and sometimes fatal events can occur. There have been reports
of serious infections including tuberculosis (TB) and infections
caused by bacteria, fungi, or viruses that have spread
throughout the body. Lymphoma, including a fatal kind called
Hepatosplenic T-cell lymphoma, and other cancers have been
How long will you feel better?
In a one-year study of kids with Crohn’s and UC, many of the
kids said they felt symptom relief within two weeks of their first
treatment. And for most of the kids who continued treatment
with REMICADE® every eight weeks, symptom relief lasted for
the entire study.
Talk with your parents and your doctor to see if REMICADE®
is right for you. Maybe REMICADE® can help you feel better
through the control of your symptoms.
Please read and talk to your parents and your doctor about the
Medication Guide for REMICADE® enclosed in the pocket of this
brochure.
reported in children and adults taking Remicade®. Some people
with heart failure should not take Remicade®. Other serious side
effects reported include skin cancer, hepatitis B, liver injury, blood
problems, allergic reactions, nervous system problems, or
lupus-like syndrome. To learn more about these and other risks,
please read the Important Safety Information on pages 16–19
and the enclosed Medication Guide, and talk with your doctor.
31
How can you talk
to your friends
about Crohn’s
or UC?
Having Crohn’s or UC is pretty personal, and though it’s not your
fault, you probably feel self-conscious about it. Discussing it can
be uncomfortable. You may only want to talk about it with your
family and closest friends. Or maybe you want to tell everybody
so you don’t have to worry about keeping it a secret. Whatever
you decide to do is the right choice because it’s your choice.
Here are a few ideas that can help make it easier to tell your
friends about your condition:
• Speak from your heart: If you’re nervous about talking about
Crohn’s or UC, say so. Real friends will appreciate your honesty.
• Think about what you want to say: Maybe you want to say
that Crohn’s and UC are serious conditions that cause you to
have stomach pain and make you really tired. Maybe not. But
figuring it out ahead of time will make it easier to talk about.
• Explain the symptoms: Everyone can relate to stomach pain
and tiredness. As quiet as they may keep it, most of your
friends can relate to having diarrhea too, but how much you
share is totally up to you.
• Answer questions: It’ll stop your friends’ imaginations from
running wild, and let you know if they understand what you’ve
been saying. The main thing they’ll probably want to know is
that Crohn’s and UC are not contagious...they can’t catch it
from you.
• Try to have a sense of humor: If you can make a joke or laugh
about your Crohn’s or UC, chances are you can make your
friends feel more at ease too.
For loads of great tips and discussion suggestions like these,
visit www.ucandcrohns.org and click on “TIPS.”
33
Appointment
Prep Guide
Review this with your child
to make the most out of
your doctor visit.
Five ways to “connect” more:
1. Tell your story in 3 chapters:
• The past—give a quick “snapshot” of what your
condition has been like since your last
appointment.
• The present—describe what your symptoms
are like currently.
• The future—share specific treatment goals, like:
“I don’t want to miss out on school anymore
because I’m sick.”
2. Describe—don’t minimize—your symptoms.
Tell it like it is.
3. Talk about how you deal with your symptoms,
not just how you feel physically.
4. Review your current treatment—how it’s
working and any side effects you may be
experiencing.
5. Remember, connecting goes both ways—take
a pad to jot down notes during your visit.
See the
appointment
prep guide
inside...
For your kids with Crohn’s and
Ulcerative Colitis, learn more
about REMICADE®.
• REMICADE® has been shown to help kids with moderately to
severely active Crohn’s and ulcerative colitis who haven’t
responded well to other therapies achieve control over Crohn’s
and ulcerative colitis symptoms. Many children being treated
with REMICADE® also experience periods of no symptoms or
very few symptoms, or remission. Individual results may vary.
• After the first 3 treatments, children with Crohn’s and
ulcerative colitis need REMICADE® only once every 8 weeks.
That could be as few as 6 times a year. Treatment with
REMICADE® offers infrequent dosing that is customized based
on body weight. REMICADE® is given as a 2-hour IV infusion
by a healthcare professional.
Help your child
take control of
Crohn’s or
Ulcerative Colitis
symptoms
Ask your doctor about
REMICADE® today.
SELECTED Important SAFETY INFORMATION
Remicade® can lower your ability to fight infections.
Serious and sometimes fatal events can occur. There have been
reports of serious infections including tuberculosis (TB) and
infections caused by bacteria, fungi, or viruses that have spread
throughout the body. Lymphoma, including a fatal kind called
Hepatosplenic T-cell lymphoma, and other cancers have been
reported in children and adults taking Remicade®. Some people
with heart failure should not take Remicade®. Other serious
side effects reported include skin cancer, hepatitis B, liver injury,
blood problems, allergic reactions, nervous system problems,
or lupus-like syndrome. To learn more about these and other
risks, please read the Important Safety Information on pages
16–19 and the enclosed Medication Guide, and talk with
your doctor.
Visit www.remicade.com
and sign up for valuable
resources and support,
or call (877) 482-7840
for more information.
©Janssen Biotech, Inc. 2013
11/13
006099-131111
REMICADE® can reduce signs and symptoms and induce
and maintain clinical remission in pediatric patients six years
of age and older with moderately to severely active Crohn’s
disease and ulcerative colitis who haven’t responded well
to other therapies.