Help your child take control of Crohn`s or Ulcerative Colitis symptoms
Transcription
Help your child take control of Crohn`s or Ulcerative Colitis symptoms
Appointment Prep Guide Review this with your child to make the most out of your doctor visit. Five ways to “connect” more: 1. Tell your story in 3 chapters: • The past—give a quick “snapshot” of what your condition has been like since your last appointment. • The present—describe what your symptoms are like currently. • The future—share specific treatment goals, like: “I don’t want to miss out on school anymore because I’m sick.” 2. Describe—don’t minimize—your symptoms. Tell it like it is. 3. Talk about how you deal with your symptoms, not just how you feel physically. 4. Review your current treatment—how it’s working and any side effects you may be experiencing. 5. Remember, connecting goes both ways—take a pad to jot down notes during your visit. See the appointment prep guide inside... For your kids with Crohn’s and Ulcerative Colitis, learn more about REMICADE®. • REMICADE® has been shown to help kids with moderately to severely active Crohn’s and ulcerative colitis who haven’t responded well to other therapies achieve control over Crohn’s and ulcerative colitis symptoms. Many children being treated with REMICADE® also experience periods of no symptoms or very few symptoms, or remission. Individual results may vary. • After the first 3 treatments, children with Crohn’s and ulcerative colitis need REMICADE® only once every 8 weeks. That could be as few as 6 times a year. Treatment with REMICADE® offers infrequent dosing that is customized based on body weight. REMICADE® is given as a 2-hour IV infusion by a healthcare professional. Help your child take control of Crohn’s or Ulcerative Colitis symptoms Ask your doctor about REMICADE® today. SELECTED Important SAFETY INFORMATION Remicade® can lower your ability to fight infections. Serious and sometimes fatal events can occur. There have been reports of serious infections including tuberculosis (TB) and infections caused by bacteria, fungi, or viruses that have spread throughout the body. Lymphoma, including a fatal kind called Hepatosplenic T-cell lymphoma, and other cancers have been reported in children and adults taking Remicade®. Some people with heart failure should not take Remicade®. Other serious side effects reported include skin cancer, hepatitis B, liver injury, blood problems, allergic reactions, nervous system problems, or lupus-like syndrome. To learn more about these and other risks, please read the Important Safety Information on pages 16–19 and the enclosed Medication Guide, and talk with your doctor. Visit www.remicade.com and sign up for valuable resources and support, or call (877) 482-7840 for more information. ©Janssen Biotech, Inc. 2013 11/13 006099-131111 REMICADE® can reduce signs and symptoms and induce and maintain clinical remission in pediatric patients six years of age and older with moderately to severely active Crohn’s disease and ulcerative colitis who haven’t responded well to other therapies. Are your child’s symptoms under control? Your child’s symptoms can interfere with his or her activities. The symptoms of moderately to severely active Crohn’s disease and ulcerative colitis can interrupt your child’s daily routine. If your son or daughter is taking medication and still experiencing symptoms, they may not be under control. You and your child may have learned to live with your current treatment but you don’t have to anymore—there are more options available. What is Crohn’s Disease? Crohn’s disease can cause inflammation anywhere in your digestive tract and usually occurs in the lower part of the small intestine or colon. Symptoms generally include stomach pain, cramping, diarrhea, weight loss and fever. What is Ulcerative Colitis? Ulcerative colitis can cause inflammation in the colon or large intestine. Symptoms generally include blood in the stool or bloody diarrhea, frequent bowel movements, rectal bleeding, stomach pain, cramping or weight loss. SELECTED important SAFETY INFORMATION Remicade® can lower your ability to fight infections. Serious and sometimes fatal events can occur. There have been reports of serious infections including tuberculosis (TB) and infections caused by bacteria, fungi, or viruses that have spread throughout the body. Lymphoma, including a fatal kind called Hepatosplenic T-cell lymphoma, and other cancers have been reported in children and adults taking Remicade®. Some people with heart failure should not take Remicade®. Other serious side effects reported include skin cancer, hepatitis B, liver injury, blood problems, allergic reactions, nervous system problems, or lupus-like syndrome. To learn more about these and other risks, please read the Important Safety Information on pages 16–19 and the enclosed Medication Guide, and talk with your doctor. 5 What are the available treatments for kids with Crohn’s and Ulcerative Colitis? Some of the medications used for adult patients are also used to treat children. The medications fall into four main categories: • 5-ASAs—such as Asacol®* (mesalamine) and Pentasa®* (mesalamine) • Steroids—such as prednisone and Entocort® EC* (budesonide) • Immunosuppressants—such as Imuran®* (azathioprine) and Purinethol®* (mercaptopurine) • Biologic therapy—such as REMICADE® (infliximab)** Only a doctor can determine which treatment is right for your child, but it’s important that you understand the differences between these medications and what they do. *Indicated trademarks are registered trademarks of their respective owners. **For moderately to severely active Crohn’s disease and ulcerative colitis in patients six years of age and older. SELECTED Important SAFETY INFORMATION Remicade® can lower your ability to fight infections. Serious and sometimes fatal events can occur. There have been reports of serious infections including tuberculosis (TB) and infections caused by bacteria, fungi, or viruses that have spread throughout the body. Lymphoma, including a fatal kind called Hepatosplenic T-cell lymphoma, and other cancers have been 5-ASAs Can reduce inflammation and help prevent flare-ups, e.g., Asacol®* (mesalamine) Pentasa®* (mesalamine) Steroids Most often used short-term to reduce inflammation in patients who have not responded well to 5-ASAs, e.g., prednisone, Entocort® EC* (budesonide) Immunosuppressants Can be used to induce and maintain remission and decrease the need for steroids, e.g., Imuran®* (azathioprine), and Purinethol®* (mercaptopurine) Biologic Used to induce and maintain remission when other therapies have failed to control symptoms. reported in children and adults taking Remicade®. Some people with heart failure should not take Remicade®. Other serious side effects reported include skin cancer, hepatitis B, liver injury, blood problems, allergic reactions, nervous system problems, or lupus-like syndrome. To learn more about these and other risks, please read the Important Safety Information on pages 16–19 and the enclosed Medication Guide, and talk with your doctor. 7 Remicade®(infliximab) is a biologic What is REMICADE® and how does it work? REMICADE® is an advanced treatment that works differently from conventional medications. It’s a protein that blocks a substance called TNF-alpha, which can cause inflammation. REMICADE® helps control this underlying cause of inflammation. What is the treatment like? The treatment process is straightforward. Your doctor may decide to give your child medicine before starting the REMICADE® infusion to prevent or lessen side effects. An IV needle will be placed in your child’s arm or hand by a healthcare professional and REMICADE® will be infused directly into the bloodstream so it can get to work. Treatment takes about two hours, during which your child can read, watch TV, do quiet work, or just relax while accompanied by a nurse. A healthcare professional will monitor your child during the Remicade® infusion and for a period of time afterward for side effects. Your doctor may do certain tests while your child is taking Remicade® to monitor for side effects and to see how well your child responds to the treatment. After the first three doses, your child will need to receive REMICADE® only once every eight weeks. That could be as few as six times a year. Is REMICADE® right for your child? REMICADE® is not for everyone; only your child’s doctor can decide if REMICADE® is right for your child. REMICADE®, like other medicines that affect your immune system, is a strong medicine that can cause serious side effects. SELECTED important SAFETY INFORMATION Remicade® can lower your ability to fight infections. Serious and sometimes fatal events can occur. There have been reports of serious infections including tuberculosis (TB) and infections caused by bacteria, fungi, or viruses that have spread throughout the body. Lymphoma, including a fatal kind called Hepatosplenic T-cell lymphoma, and other cancers have been reported in children and adults taking Remicade®. Some people with heart failure should not take Remicade®. Other serious side effects reported include skin cancer, hepatitis B, liver injury, blood problems, allergic reactions, nervous system problems, or lupus-like syndrome. To learn more about these and other risks, please read the Important Safety Information on pages 16–19 and the enclosed Medication Guide, and talk with your doctor. 9 REMICADE (infliximab) has been shown to make a difference* ® What has REMICADE® been proven to do for a child with Crohn’s or UC? In a year-long clinical study, many kids with Crohn’s disease or UC who began treatment with REMICADE® experienced: • Rapid symptom improvement, or “response” (at Week 8 for ulcerative colitis and Week 10 for Crohn’s disease) • Periods of no symptoms or very few symptoms, or clinical remission at one year • Possible elimination of steroid use for Crohn’s in some patients *Individual results may vary. REMICADE® is not for everyone. Only a doctor can decide if REMICADE® is right for your child. Please discuss any questions related to symptoms or treatment with your doctor. SELECTED important SAFETY INFORMATION Remicade® can lower your ability to fight infections. Serious and sometimes fatal events can occur. There have been reports of serious infections including tuberculosis (TB) and infections caused by bacteria, fungi, or viruses that have spread throughout the body. Lymphoma, including a fatal kind called Hepatosplenic T-cell lymphoma, and other cancers have been reported in children and adults taking Remicade®. Some people with heart failure should not take Remicade®. Other serious side effects reported include skin cancer, hepatitis B, liver injury, blood problems, allergic reactions, nervous system problems, or lupus-like syndrome. To learn more about these and other risks, please read the Important Safety Information on pages 16–19 and the enclosed Medication Guide, and talk with your doctor. 11 Crohn’s findings: In a study of 112 patients, almost 9 out of 10 (88%) children experienced symptom improvement soon (Week 10) after starting treatment with REMICADE®. Ulcerative Colitis findings: In 44 out of 60 patients (73%), children experienced symptom improvement soon (Week 8) after starting treatment with REMICADE®. REMICADE® has been shown to improve symptom control for children with Crohn’s and Ulcerative Colitis. If your son or daughter is still coping with symptoms of moderately to severely active Crohn’s disease or ulcerative colitis and they experience flare-ups more than two times per year despite treatment with other therapies, the disease may not be as under control as it could be. REMICADE® may help reduce your child’s painful and unpredictable symptoms. That’s when you know your child’s Crohn’s or ulcerative colitis symptoms are under control. SELECTED Important SAFETY INFORMATION Remicade® can lower your ability to fight infections. Serious and sometimes fatal events can occur. There have been reports of serious infections including tuberculosis (TB) and infections caused by bacteria, fungi, or viruses that have spread throughout the body. Lymphoma, including a fatal kind called Hepatosplenic T-cell lymphoma, and other cancers have been reported in children and adults taking Remicade®. Some people with heart failure should not take Remicade®. Other serious side effects reported include skin cancer, hepatitis B, liver injury, blood problems, allergic reactions, nervous system problems, or lupus-like syndrome. To learn more about these and other risks, please read the Important Safety Information on pages 16–19 and the enclosed Medication Guide, and talk with your doctor. 13 Help your child take the first step In a 54-week study for Crohn’s and a 54-week study for ulcerative colitis, children had a reduction in signs and symptoms and achieved symptom remission. REMICADE® (infliximab) is not a steroid. Some children taking REMICADE® for Crohn’s disease were able to achieve remission of symptoms. In fact, 46% of kids with Crohn’s taking steroids at the beginning of the study who received REMICADE® every 8 weeks were able to stop taking steroids while in remission by the end of the study. Individual results may vary. But remember: only your child’s doctor can decide if reducing or stopping steroids is appropriate. Like other medicines that affect your child’s immune system, REMICADE® can also cause serious side effects. Some children taking REMICADE® for ulcerative colitis were also able to achieve remission of symptoms. In fact, 24 out of 60 (40%) of kids with ulcerative colitis who received REMICADE® experienced symptom remission at Week 8 during the study. Only your child’s gastroenterologist can determine if the benefits of treatment with REMICADE® outweigh the potential risks and side effects. Today, you can help your child take the first step toward control of his or her symptoms. SELECTED Important SAFETY INFORMATION Remicade® can lower your ability to fight infections. Serious and sometimes fatal events can occur. There have been reports of serious infections including tuberculosis (TB) and infections caused by bacteria, fungi, or viruses that have spread throughout the body. Lymphoma, including a fatal kind called Hepatosplenic T-cell lymphoma, and other cancers have been reported in children and adults taking Remicade®. Some people with heart failure should not take Remicade®. Other serious side effects reported include skin cancer, hepatitis B, liver injury, blood problems, allergic reactions, nervous system problems, or lupus-like syndrome. To learn more about these and other risks, please read the Important Safety Information on pages 16–19 and the enclosed Medication Guide, and talk with your doctor. 15 Important Safety Information to discuss with your child’s doctor. Only your doctor can recommend a course of treatment after checking your health condition. REMICADE® (infliximab) can cause serious side effects such as lowering your ability to fight infections. Some patients, especially those 65 years and older, have had serious infections caused by viruses, fungi, or bacteria that have spread throughout the body, including tuberculosis (TB) and histoplasmosis. Some of these infections have been fatal. Your doctor should monitor you closely for signs and symptoms of TB during treatment with REMICADE®. Unusual cancers have been reported in children and teenage patients taking TNF-blocker medicines. Hepatosplenic T-cell lymphoma, a rare form of fatal lymphoma, has occurred mostly in teenage or young adult males with Crohn’s disease or ulcerative colitis who were taking REMICADE® and azathioprine or 6-mercaptopurine. For children and adults taking TNF blockers, including REMICADE®, the chances of getting lymphoma or other cancers may increase. You should discuss any concerns about your health and medical care with your doctor. What should I tell my doctor before I take REMICADE®? You should let your doctor know if you have or ever had any of the following: • Tuberculosis (TB) or have been near someone who has TB. Your doctor will check you for TB with a skin test. If you have latent (inactive) TB, you will begin TB treatment before you start REMICADE®. • Lived in a region where certain fungal infections like histoplasmosis or coccidioidomycosis are common. • Infections that keep coming back, have diabetes or an immune system problem. • Any type of cancer or a risk factor for developing cancer, for example, chronic obstructive pulmonary disease (COPD) or had phototherapy for psoriasis. • Heart failure or any heart condition. Many people with heart failure should not take REMICADE®. • Hepatitis B virus (HBV) infection or think you may be a carrier of HBV. Your doctor will test you for HBV. • Nervous system disorders (like multiple sclerosis or Guillain-Barré syndrome). Also tell your doctor if you: • Use the medicines Kineret (anakinra), Orencia (abatacept) or Actemra (tocilizumab) or other medicines called biologics used to treat the same problems as REMICADE®. •A re pregnant, plan to become pregnant, are breastfeeding, or have a baby and were using REMICADE® during your pregnancy. Tell your baby’s doctor about your REMICADE® use before the baby receives any vaccine because of an increased risk of infection for up to 6 months after your last dose of REMICADE® you received during your pregnancy. • Recently received or are scheduled to receive a vaccine. Adults and children taking REMICADE® should not receive live vaccines or treatment with a weakened bacteria (such as BCG for bladder cancer) while taking REMICADE®. 17 What should I watch for and talk to my doctor about before or while taking REMICADE®? The following serious (sometimes fatal) side effects have been reported in people taking REMICADE®. You should tell your doctor right away if you have any of the signs listed below: • Infections (like TB, blood infections, pneumonia)— fever, tiredness, cough, flu, or warm, red or painful skin or any open sores. REMICADE® can make you more likely to get an infection or make any infection that you have worse. • Lymphoma, or any other cancers in adults and children. • Skin cancer—any changes in or growths on your skin. • Heart failure—new or worsening symptoms, such as shortness of breath, swelling of your ankles or feet, or sudden weight gain. • Liver injury—jaundice (yellow skin and eyes), dark brown urine, right-sided abdominal pain, fever, or severe tiredness. • Blood disorders—fever that doesn’t go away, bruising, bleeding, or severe paleness. • Nervous system disorders—numbness, weakness, tingling, changes in your vision, or seizures. • Allergic reactions during or after the infusion—hives, difficulty breathing, chest pain, high or low blood pressure, swelling of face and hands, and fever or chills. • Lupus-like syndrome—chest discomfort or pain that does not go away, shortness of breath, joint pain, rash on the cheeks or arms that gets worse in the sun. The more common side effects with REMICADE® are respiratory infections (that may include sinus infections and sore throat), headache, rash, coughing, and stomach pain. • Psoriasis—new or worsening psoriasis such as red scaly patches or raised bumps on the skin that are filled with pus. 005912-131106 • Reactivation of HBV—feeling unwell, poor appetite, tiredness, fever, skin rash, and/or joint pain. Please read the accompanying Medication Guide for REMICADE®, and discuss it with your doctor. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088. 19 Frequently asked questions Q What is the goal of treating pediatric Crohn’s disease or Ulcerative Colitis with REMICADE®? A The goal is to go beyond temporary relief of symptoms to achieve Crohn’s and ulcerative colitis symptom remission, and to reduce or stop the need for steroids for children with Crohn’s. Q Is REMICADE® right for my child? A R EMICADE can lower your ability to fight infections. ® Serious and sometimes fatal events can occur. There have been reports of serious infections including tuberculosis (TB) and infections caused by bacteria, fungi, or viruses that have spread throughout the body. Lymphoma, including a fatal kind called Hepatosplenic T-cell lymphoma, and other cancers have been reported in children and adults taking REMICADE®. Some people with heart failure should not take REMICADE®. Other serious side effects include hepatitis B, liver injury, blood problems, allergic reactions, nervous system problems, or lupus-like syndrome. To learn more about these and other risks, please read the Important Safety Information on pages 16–19 and the enclosed Medication Guide, and talk with your doctor. 21 Q How is REMICADE® administered and how often will my child have to take it? A R EMICADE is given as an intravenous infusion by a ® healthcare professional, and administration takes at least two hours. After the first three doses, your child will remain on maintenance therapy, which is just once every eight weeks. That could be as few as six times a year. Q What should I know about side effects? A R EMICADE , like other medicines that affect your immune ® system, is a strong medicine that can cause serious side effects such as cancer and serious infections caused by viruses, fungi or bacteria that have spread throughout the body, including tuberculosis (TB) and histoplasmosis. Some of these side effects have been fatal. For more information about these and other serious side effects, please read the Important Safety Information on pages 16–19 and the accompanying Medication Guide for REMICADE®, and discuss them with your child’s doctor. The most common side effects of REMICADE® are mild and manageable, and include: respiratory infections, headache, rash, coughing, and stomach pain. Q What should I watch for? A You should discuss any questions or concerns about your child’s health with your child’s doctor. On pages 16–19, please read the Important Safety Information. You will also find an accompanying Medication Guide for REMICADE® that includes the most common and the most serious side effects, related symptoms and when to talk to your child’s doctor or seek medical care. If you seek medical care for your child from a healthcare professional other than the doctor who prescribed REMICADE®, it is important to let him or her know about your child’s medical history and any current medications, including REMICADE®. Q Is REMICADE® covered by insurance? A R EMICADE is covered by most commercial insurance ® plans. Coverage policies may vary by insurer, or even between plans offered by the same insurer. If you have any questions about insurance coverage or reimbursement, you should first call your insurance company. If you need additional information or patient assistance for REMICADE®, please call AccessOne® at (888) ACCESS-1 (888-222-3771), Monday through Friday, 8:00 AM to 8:00 PM, E.T. Please read the Important Safety Information for REMICADE®, included on pages 16–19, and discuss it with your child’s doctor. 23 You can help your child and your family •R EMICADE® Patient Stories Visit www.ulcerativecolitisstories.com or www.crohnsdiseasestories.com to explore stories of people who have found control from their symptoms. How else can you help your child live with Crohn’s or ulcerative colitis symptoms? • AccessOne® personal Care Coordinators are available to help answer questions about insurance coverage, provide you with additional educational materials, and assist you with appointment reminders and follow-up calls. They can also provide information about infusion sites that may be convenient to your home or your child’s school. Dealing with the symptoms of Crohn’s or ulcerative colitis can be particularly difficult for a child. But you can make a difference. In addition to providing love and support, the most significant way in which you can help your child is to learn as much as possible about the disease and available treatment options. The following resources can help you help your child, and your whole family learn more: Other resources: Resources from the makers of Remicade®: •R emiStart® If you have difficulty affording the medication out-of-pocket costs of treatment for your child, you may be eligible for financial assistance through the RemiStart® program. To find out more visit www.RemiStart.com. • Crohn’s and Colitis Foundation of America (CCFA) www.ccfa.org—provides a wide variety of information on Crohn’s disease, ulcerative colitis, support groups, education programs, events, social programs for kids with Crohn’s and ulcerative colitis, links to info on current research, and much more. • REMICADE.com includes information about Crohn’s disease, ulcerative colitis, REMICADE® (infliximab) and how it works, as well as a listing of related books. • North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) www.naspghan.org provides education and assistance with locating doctors, etc. SELECTED Important SAFETY INFORMATION Remicade® can lower your ability to fight infections. Serious and sometimes fatal events can occur. There have been reports of serious infections including tuberculosis (TB) and infections caused by bacteria, fungi, or viruses that have spread throughout the body. Lymphoma, including a fatal kind called Hepatosplenic T-cell lymphoma, and other cancers have been reported in children and adults taking Remicade®. Some people with heart failure should not take Remicade®. Other serious side effects reported include skin cancer, hepatitis B, liver injury, blood problems, allergic reactions, nervous system problems, or lupus-like syndrome. To learn more about these and other risks, please read the Important Safety Information on pages 16–19 and the enclosed Medication Guide, and talk with your doctor. 25 Information for kids & teens The real deal on Crohn’s and Ulcerative Colitis. Having Crohn’s or ulcerative colitis (UC) doesn’t mean you have to always worry about having symptoms. You can feel better and that can help you do more of the things you want to do. The important thing to remember is to be open and honest, and to discuss how you’re feeling with your parents and your doctor. They want to know how your symptoms are affecting your life so they can help find the best care and treatment for you. It can also be helpful to let other adults like your teachers and the school nurse know you have Crohn’s or UC. That way, they’ll be prepared to understand and support you when you’re not feeling well. REMICADE® may be able to help you get control over Crohn’s or UC symptoms. Individual results may vary. SELECTED important SAFETY INFORMATION Remicade® can lower your ability to fight infections. Serious and sometimes fatal events can occur. There have been reports of serious infections including tuberculosis (TB) and infections caused by bacteria, fungi, or viruses that have spread throughout the body. Lymphoma, including a fatal kind called Hepatosplenic T-cell lymphoma, and other cancers have been reported in children and adults taking Remicade®. Some people with heart failure should not take Remicade®. Other serious side effects reported include skin cancer, hepatitis B, liver injury, blood problems, allergic reactions, nervous system problems, or lupus-like syndrome. To learn more about these and other risks, please read the Important Safety Information on pages 16–19 and the enclosed Medication Guide, and talk with your doctor. 27 So what is REMICADE®(infliximab)? REMICADE® is a type of medicine that works by blocking a protein in your body that causes inflammation in your intestines. The inflammation causes diarrhea, stomach pain and fever, and you may also feel tired. REMICADE® helps reduce this inflammation. How will you receive Remicade®? Only a doctor or nurse can give you REMICADE®. That means you go to your doctor’s office or a place called an infusion center to get it. Your doctor may decide to give you medicine before starting the infusion to prevent or lessen side effects. They’ll hook up an IV infusion to your arm or hand and let the medicine drip in for two hours, kind of like you’ve seen on TV. Yeah, we know it’s kind of unusual to get medicine through an IV, but there’s a very good reason for it. When medicine is infused, it goes straight into your bloodstream and gets to work. Getting an infusion may seem weird at first, but you’ll have someone nearby during the infusion. o view a video on how REMICADE® works, scan the T code or visit the sites www.crohnsdiseasestories.com (for Crohn’s) or www.ulcerativecolitisstories.com (for UC) and click on “The Science of REMICADE®“ SELECTED important SAFETY INFORMATION Remicade® can lower your ability to fight infections. Serious and sometimes fatal events can occur. There have been reports of serious infections including tuberculosis (TB) and infections caused by bacteria, fungi, or viruses that have spread throughout the body. Lymphoma, including a fatal kind called Hepatosplenic T-cell lymphoma, and other cancers have been reported in children and adults taking Remicade®. Some people with heart failure should not take Remicade®. Other serious side effects reported include skin cancer, hepatitis B, liver injury, blood problems, allergic reactions, nervous system problems, or lupus-like syndrome. To learn more about these and other risks, please read the Important Safety Information on pages 16–19 and the enclosed Medication Guide, and talk with your doctor. 29 What should you wear to the infusion? If you want to tell your mom or dad that you need a new outfit for the infusion, we won’t say a word. But really, all you need are some comfortable clothes. Your infusion with REMICADE® will take about 2 hours, so during this time you can kick back, relax, listen to the latest tunes, even do a little school work (no getting out of that). How often do you have to go for infusions? After the first three doses, you will only have to receive REMICADE® (infliximab) every 8 weeks, or about every 2 months, or as few as 6 times a year. (Yeah, we know, they’re all the same…just wanted to see if you were paying attention.) SELECTED Important SAFETY INFORMATION Remicade® can lower your ability to fight infections. Serious and sometimes fatal events can occur. There have been reports of serious infections including tuberculosis (TB) and infections caused by bacteria, fungi, or viruses that have spread throughout the body. Lymphoma, including a fatal kind called Hepatosplenic T-cell lymphoma, and other cancers have been How long will you feel better? In a one-year study of kids with Crohn’s and UC, many of the kids said they felt symptom relief within two weeks of their first treatment. And for most of the kids who continued treatment with REMICADE® every eight weeks, symptom relief lasted for the entire study. Talk with your parents and your doctor to see if REMICADE® is right for you. Maybe REMICADE® can help you feel better through the control of your symptoms. Please read and talk to your parents and your doctor about the Medication Guide for REMICADE® enclosed in the pocket of this brochure. reported in children and adults taking Remicade®. Some people with heart failure should not take Remicade®. Other serious side effects reported include skin cancer, hepatitis B, liver injury, blood problems, allergic reactions, nervous system problems, or lupus-like syndrome. To learn more about these and other risks, please read the Important Safety Information on pages 16–19 and the enclosed Medication Guide, and talk with your doctor. 31 How can you talk to your friends about Crohn’s or UC? Having Crohn’s or UC is pretty personal, and though it’s not your fault, you probably feel self-conscious about it. Discussing it can be uncomfortable. You may only want to talk about it with your family and closest friends. Or maybe you want to tell everybody so you don’t have to worry about keeping it a secret. Whatever you decide to do is the right choice because it’s your choice. Here are a few ideas that can help make it easier to tell your friends about your condition: • Speak from your heart: If you’re nervous about talking about Crohn’s or UC, say so. Real friends will appreciate your honesty. • Think about what you want to say: Maybe you want to say that Crohn’s and UC are serious conditions that cause you to have stomach pain and make you really tired. Maybe not. But figuring it out ahead of time will make it easier to talk about. • Explain the symptoms: Everyone can relate to stomach pain and tiredness. As quiet as they may keep it, most of your friends can relate to having diarrhea too, but how much you share is totally up to you. • Answer questions: It’ll stop your friends’ imaginations from running wild, and let you know if they understand what you’ve been saying. The main thing they’ll probably want to know is that Crohn’s and UC are not contagious...they can’t catch it from you. • Try to have a sense of humor: If you can make a joke or laugh about your Crohn’s or UC, chances are you can make your friends feel more at ease too. For loads of great tips and discussion suggestions like these, visit www.ucandcrohns.org and click on “TIPS.” 33 Appointment Prep Guide Review this with your child to make the most out of your doctor visit. Five ways to “connect” more: 1. Tell your story in 3 chapters: • The past—give a quick “snapshot” of what your condition has been like since your last appointment. • The present—describe what your symptoms are like currently. • The future—share specific treatment goals, like: “I don’t want to miss out on school anymore because I’m sick.” 2. Describe—don’t minimize—your symptoms. Tell it like it is. 3. Talk about how you deal with your symptoms, not just how you feel physically. 4. Review your current treatment—how it’s working and any side effects you may be experiencing. 5. Remember, connecting goes both ways—take a pad to jot down notes during your visit. See the appointment prep guide inside... For your kids with Crohn’s and Ulcerative Colitis, learn more about REMICADE®. • REMICADE® has been shown to help kids with moderately to severely active Crohn’s and ulcerative colitis who haven’t responded well to other therapies achieve control over Crohn’s and ulcerative colitis symptoms. Many children being treated with REMICADE® also experience periods of no symptoms or very few symptoms, or remission. Individual results may vary. • After the first 3 treatments, children with Crohn’s and ulcerative colitis need REMICADE® only once every 8 weeks. That could be as few as 6 times a year. Treatment with REMICADE® offers infrequent dosing that is customized based on body weight. REMICADE® is given as a 2-hour IV infusion by a healthcare professional. Help your child take control of Crohn’s or Ulcerative Colitis symptoms Ask your doctor about REMICADE® today. SELECTED Important SAFETY INFORMATION Remicade® can lower your ability to fight infections. Serious and sometimes fatal events can occur. There have been reports of serious infections including tuberculosis (TB) and infections caused by bacteria, fungi, or viruses that have spread throughout the body. Lymphoma, including a fatal kind called Hepatosplenic T-cell lymphoma, and other cancers have been reported in children and adults taking Remicade®. Some people with heart failure should not take Remicade®. Other serious side effects reported include skin cancer, hepatitis B, liver injury, blood problems, allergic reactions, nervous system problems, or lupus-like syndrome. To learn more about these and other risks, please read the Important Safety Information on pages 16–19 and the enclosed Medication Guide, and talk with your doctor. Visit www.remicade.com and sign up for valuable resources and support, or call (877) 482-7840 for more information. ©Janssen Biotech, Inc. 2013 11/13 006099-131111 REMICADE® can reduce signs and symptoms and induce and maintain clinical remission in pediatric patients six years of age and older with moderately to severely active Crohn’s disease and ulcerative colitis who haven’t responded well to other therapies.
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