Programme for the 21st Annual Mayo Clinic-KI

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Mayo Clinic-Karolinska Institutet
21st Annual Scientific Research Meeting: September 10-11, 2015
Karolinska Institutet, Stockholm, Sweden
Conference Agenda

Wednesday, September 9, 2015
o Welcome dinner for Mayo Clinic guests and Karolinska Institutet session chairs
(by invitation only), Nanna Svartz, Aula Medica, 6-8 pm

Thursday, September 10, 2015
o Lunch outside Erling Persson-hall, Aula Medica, 12-1 pm. No food or drinks in the
Erling Persson-hall
o Optional activities for those who are interested (registration required)
 Guided tour: Aula Medica; Meet in the Lobby of Aula Medica at 5:15 pm
o Poster Session/Conference Reception with Innovation Corner in the Lobby of
Aula Medica, 6:15 – 9:00 pm

Friday, September 11, 2015
o Lunch outside Erling Persson-hall, Aula Medica, 12-12.30 pm. No food or drinks
in the Erling Persson-hall
o Steering Committee meeting in Aula Medica, Room 634, 4:00-5:30 pm
o Optional activity - guided tour of the showroom for the new Karolinska
University Hospital - two times available: (registration required)
2:00pm- 2:30 pm (Meet in the Lobby of Aula Medica at 1:40 pm)
3:00 pm- 3:30 pm (Meet in the Lobby of Aula Medica at 2:40 pm)

Saturday, September 12, 2015
o Mayo Clinic staff wrap-up meeting; Venue: Elite Palace Hotel Cafeteria, 8:00 am
o Optional afternoon activities
Don’t miss the Innovation and Grants Office Corner
at the Poster Session, September 10.
Come and discuss your questions and thoughts with our experts!
Campus WIFI: KI-Guest //Password: medicaHT2015
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Opening/Plenary Session: Thursday, September 10, 2015
Venue: Erling Persson-hall, Aula Medica, Nobels Väg 6
Program Chairs and Moderators: Dr. Martin Schalling (KI) and Dr. Eric Wieben (MC)
8:15 am
Registration
Outside of Erling Persson-hall, Aula
Coffee and juice will be available
Medica
9:00
Leadership Greetings
Dr. Kerstin Tham (KI), Pro-ViceChancellor/Vice-President
9:05
Overview of Mayo Clinic/Karolinska Institutet Education,
Dr. Eric Wieben (MC)
Research and Innovation Platform
Dr. Martin Schalling (KI)
9:25
Plenary speaker
Dr. Richard L. Ehman (MC)
Magnetic Resonance Elastography: A New Touch in
Medical Imaging
10:05
Plenary speaker
Dr. Staffan Holmin (KI)
Endovascular navigation and multimodal imaging: Time to
redraw the map?
10:45
Break
11:00
David H. Murdock Lecture
Introduced by Dr. K. Sreekumaran Nair, David H. Murdock Dole Food Company Professor of
Nutrition Science
Lecturer: Dr. Michael Snyder
Dr. Michael Snyder is the Stanford (California) University School of Medicine’s Ascherman
Professor and Chair of Genetics and the Director of the Center of Genomics and Personalized
Medicine. Dr. Snyder received his PhD training at the California Institute of Technology and
received postdoctoral training at Stanford University.
noon
1:00 pm
Lunch outside of Erling Persson-hall, Aula Medica
Breakout session locations are noted below
Friday lunch Keynote Lecture, September 11, 2015
Venue: Erling Persson-hall, Aula Medica, Nobels Väg 6
Moderator: Dr. Eric Wieben (MC) and Dr. Martin Schalling (KI) and
12:30 pm Keynote Speaker: Phil Lombardo
– 1:15
Cognitive computing and machine learning: Using the
pm
IBM Watson technology to transform research and
clinical data into knowledge solutions
Venue: Erling Persson-hall, Aula
Medica
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Theme-Related Breakout Sessions
Thursday afternoon, September 10, 2015
Diabetes and Metabolism, Venue: Erling Persson-hall, Aula Medica,
Nobels Väg 6
Program Chairs: Dr. Olav Rooyackers (KI), Dr. Olle Ljungqvist (KI), Dr. Ian Lanza (MC), Dr. Adrian Vella
(MC) and Dr. Sree Nair (MC)
1:00 pm
Welcome and Overview of Sessions
Dr. Olav Rooyackers (KI)
Session: MISCELLANEOUS
Moderator:
Dr. Sree Nair (MC)
1:05
Alleviation of multiple age-related conditions, including Dr. James Kirkland (MC)
diabetes, by clearing senescent cells genetically or by
novel senolytic drug
1:25
Incorporating kidney function into healthcare
Dr. Juan-Jesus Carrero-Roig (KI)
management: The Stockholm CREAtinine
Measurements (SCREAM) project
1:45
Low copy number of the AMY1 locus is associated with Dr. Anna Lindstrand (KI)
early-onset female obesity
Session: FAT METABOLISM
Moderator:
Dr. John Wahren (MC)
2:05
Non-alcoholic fatty liver disease: Possible roles of
Dr. Michael Jensen (MC)
hepatic FFA uptake, VLDL secretion, liver sphingolipids
and fat oxidation
2:25
Human bone marrow contributes to adipogenesis
Dr. Mikael Ryden (KI)
2:45
Incorporation of plasma saturated free fatty acids into
Dr. Kazanna Hames (MC)
intramyocellular lipids is greater in adults with obesity
3:05
Break
Session: AUTOPHAGY
Moderator:
Dr. Olav Rooyackers (KI)
3:35
Role of autophagy in organ failure
Dr. Nicolas Tardif (KI)
3:55
Study of role of autophagy in diabetes using a novel
Dr. Manjunatha Shankarappa
methodology: Capillary Electrophoresis-Laser Induced
(MC)
Fluorescence (CE-LIF)
Session: MUSCLE
Moderator:
Dr. Ian Lanza (MC)
4:15
Development of small molecule PGC-1alpha activators
Dr. Amanda Pettersson (KI)
as therapeutics for metabolic disease
4:35
Testosterone and muscle growth
Dr. Amarjit Saini (KI)
4:55
5:15
Bench to bedside research on critical myopathy (CIM)
and ventilator – Induced diaphragm muscle dysfunction
(VIDD): Mechanisms and intervention strategies
Closing and Announcements
Dr. Lars Larsson (KI)
All
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Administration, Venue: Strix, von Eulers väg 4 A/B
Program Chairs and Moderators: Dr. Björn Kull (KI) and Mr. David Moertel (MC)
1:00 pm
Welcome and Introductions
David Moertel (MC)
Dr. Björn Kull (KI)
1:10
Mayo Clinic Office of Sponsored Project
Jon Zurn (MC)
Administration/Karolinska Institutet Grants Office Joint Dr. Ylva Linderson (KI)
Development Collaboration
Dr. Laura Plant (KI)
1:40
Sharing of Best Practices for Research Space Allocation
Jill Blomstrand (KI), Mark Zobitz
(MC)
2:10
Using Biobanks in KI-Mayo collaboration
Dr. Cecilia Björkdahl (KI), Jim
Cerhan (MC)
2:40
Procurement of Innovation
Fredrik Lundkvist (KS)
3:10
Break
3:30
Indirect Rates Discussion
Rich Alitz (MC)
Dr. Ylva Linderson (KI)
3:50
The Importance of the Collaborative Grant Awards
Dr. David Murray (MC)
Program from Multi-Year Recipients
Dr. Susanna Lundstöm (KI)
Autoimmune Disorders, Venue: Petrénsalen, Nobels väg 12B
Program Chairs and Moderators: Dr. Elisabet Svenungsson (KI) and Dr. Timothy Niewold (MC)
1:00 pm
Outcomes and consequences of SLE treatment with
Dr. Ioannis Parodis (KI)
focus on Benlysta and Rituximab
1:40
Impact of type I IFN on the human immune response in Dr. Uma Thanarajasingam (MC)
SLE
2:20
Break
2:40
3:20
4:00-4:30
Update on lupus nephritis, the role of biopsies and
current treatment regimes -Interferon-λ, a potential
biomarker in lupus nephritis
Functional genetics in systemic lupus erythematosus
(SLE)
Open slot for discussion
Dr. Iva Gunnarsson (KI)
Dr. Timothy Niewold (MC)
Cancer, Venue: Wretlindsalen, Tomtebodavägen 18A, floor 2
Program Chairs: Dr. Bengt Fadeel (KI) and Dr. Dev Mukhopadhyay (MC)
Session 1
Chairs: Dr. Dev Mukhopadhyay (MC) and Dr. Bengt Fadeel (KI)
1:00-1:15
pm
Welcome and Update on Mayo Clinic – Karolinska
Institutet cancer collaboration
Dr. Bengt Fadeel (KI)
Dr. Dev Mukhopadhyay (MC)
1:15-1:30
Clinical care, research and education at the new
Karolinska University Hospital (NKS): An overview
Cytochrome P4502W1, a novel drug target for
treatment of colorectal cancer
Dr. Jan-Inge Henter (Karolinska
University Hospital)
Dr. Magnus Ingelman-Sundberg (KI)
1:30
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1:50
2:10
2:30
2:50
3:20
3:40
4:00
4:20
4:40
Proteogenomics: From cancer genotype to phenotype
by proteomics
Proteosomal deubiqutinases as novel targets for
cancer therapy
Targeted interference of USP14 and UCHL5 as a
clinical strategy for the treatment of B cell lymphomas
Break
Bio-functionalized implants in proton beam
radiotherapy
Personalized pancreatic cancer therapy
In vitro and in vivo efficacy of a synergistic drug
combination for pancreatic cancer
Pancreatic cancer and microparticles
General discussion
Dr. Janne Lehtiö (KI)
Dr. Stig Linder (KI)
Dr. Aneel Paulus (MC)
Dr. Aman Anand (MC)
Dr. Matthias Löhr (KI)
Dr. Anil Sharma (MC)
Dr. Dev Mukhopadhyay (MC)
All
Cardiovascular Diseases, Venue: CMM, Building L8, bottom floor;
Karolinska University Hospital, Solna
Program Chairs and Moderators: Dr. Magnus Bäck (KI) and Dr. Joerg Herrmann (MC)
1:15 pm
Aortic valve stenosis and calcification: myths and facts
Dr. Maurice Enriquez-Sarano (MC)
1:40
Aortic dilatation in bicuspid aortic stenosis
Dr. Anders Franco-Cereceda (KI)
2:05
From biology to bedside: Leveraging preclinical models Dr. Jordan Miller (MC)
and clinical expertise to accelerate development of
novel treatments for age-related cardiovascular disease
2:30
Chronic kidney disease –a clinical model for studies of
Dr. Peter Stenvinkel (KI)
premature vascular aging
3:00
Break
3:20
Cardiovascular research using Swedish health registries Dr. Tomas Jernberg (KI)
3:45
Sleep, death and the heart
Dr. Virend Somers (MC)
4:10
Radiation-induced vascular inflammation
Dr. Martin Halle (KI)
4:35
Vascular toxicity of cancer therapy
Dr. Joerg Herrmann (MC)
Education, Venue: Wallenbergsalen, Nobel Forum, Nobels väg 1
Online education and education support: Program Chairs and Moderators: Dr. Jan-Olov Höög (KI) and Dr.
Jim Maher (MC)
1:00 pm
Introduction to higher education at Karolinska Institutet Dr. Annika Östman Wernerson (KI)
1:10
Overview of education at Mayo Clinic
Dr. Scott Seinola
1:25
eLearning: A global perspective
Dr. Nabil Zary (KI)
Anneliese Lilienthal (KI)
Carl Gornitzki (KI)
1:40
Online education
Barbara Thomas Baasch (MC)
1:55
How to produce “world-class” massive open online
Dr. Andreas Montelius (KI)
courses (MOCC)
2:10
Shared Mayo Clinic-Karolinska course in regenerative
Dr. Tony Windebank (MC)
medicine
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2:25
Break
2:45
Creation and assessment of online faculty development
resources delivered through a webpage education
platform
Open education resources and the flipped classroom
An education data warehouse
3:00
3:15
3:30
3:45
4:00
4:15- 4.45
MOOCs as a faculty branding tool
Mayo Clinic online
Systematic approach to teaching and training in clinical
settings
Open discussion
Dr. Heather Billings (MC)
Dr. Cormac McGrath (KI)
Paul Zobitz (MC)
Irene Selle (MC)
Dr. Jan-Olov Höög (KI)
Dr. David Cook (MC)
Dr. Tanja Tomson (KI)
Dr. Margaretha Forsberg Larm (KI)
All
Infectious Diseases, Venue: Room 216, Retzius väg 13 A/B
Program Chairs and Moderators: Dr. Anna Norrby-Teglund (KI) and Dr. Nathan Cummins (MC)
1:00 pm
Welcome and introduction to session
Dr. Anna Norrby-Teglund (KI)
1:05
Bcl2 antagonists for an HIV cure
Dr. Andrew Badley (MC)
1:25
Definition of immune repertoires and antibody lineages Dr. Gunilla Karlsson-Hedestam (KI)
by next generation sequencing
1:45
The Role of immunogenetics in vaccine development
Dr. Inna Ovsyannikova (MC)
2:05
2:25
2:45
3:05
3:25
3:45
4:05
4:25
4:45
A novel nano-membrane technology platform for
vaccine development
Break
Single-cycle adenovirus vectors
Combining the best of two worlds in vaccinology:
Adenoviral vectors and naked DNA in prime-boost
strategies
Surprising findings from the Swedish sepsis register
S. aureus pneumonia
S. aureus pore-forming toxins more than just pores
Trans-endocytosis transfers measles virus infection
from nectin-4 to nectin-1-expressing epithelial cells
Discussion and closing
Dr. Jens Frauenfeld (KI)
Dr. Michael Barry (MC)
Dr. Matti Sällberg (KI)
Dr. Jonas Sundén-Cullberg (KI)
Dr. Govinder Rajagopalan (MC)
Srikanth Mairpady Shambat (KI)
Dr. Roberto Cattaneo (MC)
All
Psychology and Psychiatry, Venue: Air & Fire, Science for Life
Laboratory, Tomtebodavägen 23A
Program Chairs and Moderators: Dr. Martin Schalling (KI) and Dr. Mark Frye (MC)
1:00 pm
Welcome and overview of program
Dr. Mark Frye (MC), Dr. Martin
Schalling (KI)
1:00
Alterations in circadian entrainment precede the onset
Dr. Sandra Ceccatelli (KI)
of depression-like behavior that does not respond to
fluoxetine
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1:20
1:40
2:00
2:20
2:40
3:00
3:20
3:40
4:00
4:20
4:40-5:00
Abberrant tyrosin transport across plasma membrane an endophenotypic marker for schizophrenia
Striatal Ablation of Neurogranin Increase Ethanol
Seeking and Schizophrenia-like Behaviors
Corticosterone oscillations during mania induction in
the lateral hypothalamic kindled rat - experimental
observations and mathematical modelling
Increases in Kynurenine Pathway Activity Adversely
Affects Cognitive Function: Implication for GlutamateNMDA Receptor Signaling in Schizophrenia
Telomerase dysregulation in the hippocampus of a rat
model of depression. Normalization by lithium
Break
Association of elevated body mass index with bipolar
disorder is modified by TCF7L2 genetic variants
Elevation of Il6 is associated with disturbed let-7
biogenesis in a genetic model of depression
Economic Impact of Suicidality in Manic Patients with
Depressive Features –a Swedish Registry Study
Dr. Lena Flyckt (KI)
Genes associated with increased fasting glucose in
patients with schizophrenia spectrum disorders and
bipolar disorder.
Closing Discussions
Dr. Dzana Hukic (KI)
Dr. Doo-Sup Choi (MC)
Dr. Vladana Vukojevic (KI)
Dr. Alfredo Oliveros (MC)
Dr. Catharina Lavebratt (KI)
Dr. Joanna Biernacka (MC)
Dr. Yabin Wei (KI)
Dr. Jonas Eberhard (KI)
All
Regenerative Medicine, Venue: Room 617, floor 6, Aula Medica, Nobels
väg 6
Program Chairs and Moderators: Dr. Karl-Henrik Grinnemo (KI) and Dr. Andre van Wijnen (MC)
1:10 pm
Introductions and welcome
Dr. Karl-Henrik Grinnemo (KI)
Dr. Andre van Wijnen (MC)
1:20
Metabolomic characterization of mesenchymal
Dr. Ivana Bulatovic (KI)
stromal cells from human fetal heart- does this predict
differentiation capacity?
1:40
Patient-specific pluripotent stem cells as tools for
Dr. Saranya Wyles (MC)
cardiovascular disease modeling and drug repurposing
2:00
Renal cell transplantation, the Karolinska experience
Dr. Torbjörn Lundgren (KI)
2:20
Break
2:40
Mechanism of mesenchymal stem cell-induced
Dr. Abba Zubair (MC)
neuron recovery and anti-inflammation
3:00
Hepatocyte transplantation as a treatment for Crigler- Dr. Carl Jorns (KI)
Najjar?
3:20
Peripheral neuropathy in a dish: The use of patientDr. Nathan Staff (MC)
derived sensory neurons derived from IPSCs to
explore pathogenic mechanisms
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3:40
4:00
4:20
4:40
Dissecting the cellular mechanisms behind
neurodevelopmental disorders using iPS derived
cellular models
Adult neural stem cells: A promising therapeutic
target for combating age-related cognitive deficit
Regeneration of scarred vocal folds with mesenchymal
stem cells, a clinical study
Overcoming Critical Size Nerve Defect: Conditioning of
Nerve Conduits
Dr. Anna Falk (KI)
John Welby (MC)
Dr. Stellan Hertegård (KI)
Dr. Huan Wang (MC)
Science of Health Care Delivery/Value-Based Health Care, Venue:
Lecture Hall, CMB, Berzelius väg 21
Program Chairs: Dr. Jörgen Nordenström (KI) and Dr. Veronique Roger (MC)
1:10 pm
Welcome and Overview of Session
Dr. Jörgen Nordenström (KI)
Dr. Veronique Roger (MC)
1:15-2:45
Value and leadership in healthcare
Session Chairs:
Dr. Tim Beebe (MC), Dr. Jörgen Nordenström (KI)
1:15
Big data: Will it improve the value of health care?
Dr. Veronique Roger (MC)
1:30
Leadership for value-based healthcare – From concept
Dr. Johan Thor (KI)
to practice
1:45
The High Value Health Care Collaborative
Dr. Lucy Savitz
(Intermountain Health Care)
2:00
Reorganizing Karolinska Univ. Hosp. for VBHC
Dr. Andreas Ringman Uggla (KS)
2:15
Integrating the power of patient-reported outcomes in Dr. Tim Beebe (MC)
patient care
2:30
Panel discussion
Led by:
Dr. Tim Beebe (MC)
Dr. Jörgen Nordenström (KI)
2:45-3:15
Break
3:15-4:45
Population research: Can it transform health care?
Session Chairs:
Dr. Alanna Chamberlain (MC), Dr. Johan Thor (KI)
3:15
A push for data-driven improvement: Sweden’s
Dr. Mats Brommels (KI)
investment in National Quality Registries
3:30
The Rochester Epidemiology Project and population
Dr. Alanna Chamberlain (MC)
health
3:45
Patient co-production: Using clinical databases as a tool Dr. Sofia Ernestam (KI)
for communication and shared decision-making in
rheumatology
4:00
Researching cancer surgery outcomes in the elderly:
Dr. John (Jay) Bergquist (MC)
Examples from the National Surgical Quality
Improvement Program (NSQIP) and the National Cancer
Data Base (NCDB)
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4:15
4:30-4:45
The patients’ value-chain through healthcare and
research
Panel discussion
Dr. Yvonne Wengström (KI)
Dr. Per Hall (KI)
Led by:
Dr. Alanna Chamberlain (MC)
Dr. Johan Thor (KI)
Neurodegeneration, Venue: Andreas Vesalius, Berzelius väg 3
Program Chairs and Moderators: Dr. Agneta Nordberg (KI), Dr. Prashanthi Vemuri (MC) and Dr. Melissa
Murray (MC)
1:00 pm
Welcome and Overview of Session
Dr. Agneta Nordberg (KI)
Dr. Prashanthi Vemuri (MC)
Dr. Melissa Murray (MC)
1:10
Recent development in imaging biomarkers and early
Dr. Agneta Nordberg (KI)
diagnosis of Alzheimer´s disease
1:30
Cognitive decline in the elderly and the role of cognitive Dr. Prashanthi Vemuri (MC)
reserve
1:50
Life course indicators of cognitive reserve and risk of
Dr. Hui Xin Wang (KI)
dementia
2:10
Neuropathologic underpinnings of neuroimaging
Dr. Melissa Murray (MC)
biomarker-defined SNAP cases
2:30
Inflammation in Alzheimer´s disease
Dr. Marianne Schultzberg (KI)
2:50
3:20
4:00
4:20
4:40
Break
Divergent time course of astrocytosis and amyloid
deposition in AD as measured by PET
Endoplasmic reticulum-mitochondria interplay in
Alzheimer’s disease
Mitochondria target therapeutics
Large-scale networks in early Parkinson's disease
Panel discussion
5:00
Closing
3:40
Dr. Elena Rodriguez-Vieitez (KI)
Dr. Maria Ankarcrona (KI)
Dr. Eugenia Trushina (MC)
Dr. Joana Pereira (KI)
Led by: Dr. Agneta Nordberg (KI)
Dr. Prashanthi Vemuri (MC)
Dr. Melissa Murray (MC)
All
Individualized Medicine, Venue: Charles, Tomtebodavägen 18 A
Program Chairs and Moderators: Dr. Olli Kallioniemi (KI), Dr. Fredrik Wiklund (KI) and Dr. Stephen
Thibodeau (MC)
12:58 pm
Welcome and Overview of Session
Dr. Olli Kallioniemi (KI)
Dr. Stephen Thibodeau (MC)
1:00
The Mayo Clinic Biobank: A Resource for precision
Dr. Jim Cerhan (MC)
medicine
Dr. Janet Olson (MC)
1:30
How biobanking at Karolinska Institutet supports
Dr. Mark Divers (KI)
precision medicine
Dr. James Thompson (KI)
2:00
Epigenomics in Individualized Medicine: Translating
Dr. Tamas Ordog (MC)
transcriptional regulation
10
2:20
2:40
3:00
3:20
3:40
4:00
4:20
5:00
Is sequencing-based breast cancer diagnostic ready to
replace routine pathology?
Break
Biomarker discovery at Mayo Clinic
Risk-based prostate cancer screening: Results from the
STHLM3 diagnostic trial
The ethical stewardship of large DNA biobanks
A Swedish learning health care system – What does it
take?
Discussion
Closing
Dr. Mattias Rantalainen (KI)
Dr. George Vasmatzis
Dr. John Cheville (MC)
Dr. Martin Eklund (KI)
Dr. Richard Sharp (MC)
Dr. Mats G Hansson (KI)
All
11
Theme-Related Breakout Sessions
Friday, September 11, 2015
Diabetes and Metabolis, Venue: Erling Persson-hall, Aula Medica, Nobels
Väg 6
Program Chairs: Dr. Olav Rooyackers (KI), Dr. Olle Ljungqvist (KI), Dr. Ian Lanza (MC), Dr. Adrian Vella
(MC) and Dr. Sree Nair (MC)
9:00 am
Welcome and Overview of Sessions
Dr. Olav Rooyackers (KI)
Session: INSULIN SECRETION AND ACTION
Moderator:
Dr. Olle Ljungqvist (KI)
9:05
Effect of rates of insulin secretion, pulse amplitude and Dr. Ron Varghese (MC)
frequency on fasting endogenous glucose production in
nondiabetic subjects
9:25
Pancreatic β-cell circadian clock is essential for beta cell Dr. Aleksey Matveyenko (MC)
expansion and metabolic adaptation to diet induced
obesity
9:45
Improving type 2 diabetes through a novel distinct
Dr. Tore Bengtsson (Stockholm
beta-adrenergic signalling pathway
University)
10:05
Break
Session: FISH OIL
10:35
Omega-3 fatty acids to combat sarcopenia
10:55
11:15
Update on OmegAD study
Effect of fish oil supplementation on coagulation and
fibrinolysis in obese adolescents
Use of IBM Watson Cognitive Computing Technology to
Match Oncology Patients to Clinical Trials
12:30-1:15
Session: METABOLIC ADAPTATIONS
1:45
Metabolic adaptations of hibernating bears
2:05
Dissociation between training gains in insulin sensitivity
and mitochondrial respiration following 12-weeks of
high-intensity aerobic interval, resistance, or combined
training in 18-30 and 65-80 year old humans
The metabolic effects of the 5:2 diet in diabetic and
non-diabetic subjects
Mechanism by which caloric restriction improves
insulin sensitivity in sedentary obese adults
Closing remarks
2:25
2:45
3:05
Moderator:
Dr. Michael Jensen (MC)
Dr. Antigoni Lalia (MC)
Dr. Jan Palmblad (KI)
Dr. Babu Balagopal (Nemours)
Phil Lombardo (MC)
Venue: Erling Persson-hall,
Aula Medica
Moderator:
Dr. Adrian Vella (MC)
Dr. Peter Stenvinkel (KI)
Dr. Matthew Robinson (MC)
Dr. Kerstin Brismar (KI)
Dr. Matthew Johnson (MC)
All
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Autoimmune Disorders, Venue: Atrium, Nobels väg 12 A/B
Program Chairs and Moderators: Dr. Anca Catrina (KI) and Dr. Theresa Wampler Muskardin (MC)
8:30 am
Type I interferon as a predictor of TNF response in RA Dr. Theresa Wampler Muskardin
(MC)
9:10
The lung microbiome, clues for RA disease
Vijay Joshua Balasingh (KI)
pathogenesis
9:50
Break
10:10
Microbiome in murine arthritis models
Dr. Veena Taneja (MC)
10:50
Proteomic analysis of the peripheral blood and
therapy prediction to methotrexate in early
untreated RA
The pathogenic link between lungs and joints in
rheumatoid arthritis
Use of IBM Watson Cognitive Computing Technology
to Match Oncology Patients to Clinical Trials
Dr. Aase Hensvold (KI)
11:30
12:30 pm
Neuroinflammation and New Technologies
Chairs: Dr. Per-Johan Jakobsson and Dr. Uma Thanarajasingam (MC)
1:00
Genes and environment in multiple sclerosis
Dr. Aikaterini Chatzidionysiou (KI)
Phil Lombardo (MC)
Venue: Erling Persson-hall, Aula
Medica
Dr. Tomas Olsson (KI)
1:40
2:20
Role of CD8 T cells in blood-brain barrier permeability
Break
Dr. Aaron Johnson (MC)
2:40
Use of proteomics/metabolomics to identify
biomarkers in SLE and myositis
Phenotyping Immunoglobulins in Patient Serum using
Mass Spectrometry
Microparticles: Future Biomarkers of Systemic
Autoimmune Diseases?
Dinner for Autoimmune session participants by
invitation only
Dr. Helena Idborg (KI)
3:20
4:00-4:30
7 pm
Dr. David Barnidge (MC)
Dr. Fariborz Mobarrez (KI)
Email
([email protected]) for
further details.
Cancer, Venue: Wretlindsalen, Tomtebodavägen 18A, floor 2
Program Chairs: Bengt Fadeel (KI) and Dr. Dev Mukhopadhyay (MC)
Session 2
Chairs: Dr. Panagiotis Anastasiadis (MC) and Dr. Arne Östman (KI)
8:30 am
Targeting DNA repair in anti-cancer treatments
8:50
MTH-1 inhibition in biliary tract malignancies: concept
exploration using patient-derived xenografts
9:10
Testing MTH1 inhibition as a novel therapeutic strategy
for ovarian cancer
9:30
Unravelling the genotype-phenotype relation in splicefactor SF3B1 mutated sideroblastic anemia
Dr. Thomas Helleday (KI)
Dr. John (Jay) Bergquist (MC)
Dr. Andrea Wahner Hendrickson
(MC)
Dr. Eva Hellström-Lindberg (KI)
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9:50
10:10
10:40
11:00
11:20
11:40
12:00
12:30 pm
Comprehensive genomic analysis and drug repurposing
screening in hypomethylating agent failure in AML and
MDS
Break
Mutant p53 reactivation as a strategy for efficient
cancer therapy
TGFβ-induced invasion and metastasis is mediated by
downregulation of MYC in basal breast cancer cells
Loss of tissue architecture in metastatic disease
Improved treatment efficacy of anti-angiogenic therapy
when combined with picornavirus vaccination in the
GL261 glioma model
ROR1 – a novel RTK targeted therapy in malignancies
Cognitive computing and machine learning: Using the
IBM Watson technology to transform research and
clinical data into knowledge solutions
Dr. Raoul Tibes (MC)
Dr. Klas Wiman (KI)
Dr. Derek Radisky (MC)
Dr. Lars Holmgren (KI)
Dr. Aaron Johnson (MC)
Dr. Håkan Mellstedt (KI)
Phil Lombardo (MC)
Venue: Erling Persson-hall, Aula
Medica
Session 3
Chairs: Dr. Derek Radisky (MC) and Dr. Rune Toftgård (KI)
2:00
2:20
2:40
3:00
3:20-3:50
Prognostic and response-predictive impact of markerdefined perivascular cell subsets
PD-1 mediates paralysis of tumor-infiltrating dendritic
cells through SHP-2 dependent and independent NFKB
inactivation
Laminin isoforms in tumor invasion and metastasis
MPRIP determines RhoA effector selectivity in GBM
Closing Discussions
Dr. Arne Östman (KI)
Dr. Keith Knutson (MC)
Dr. Manuel Patarroyo (KI)
Dr. Panagiotis Anastasiadis (MC)
All
Education, Venue: Wallenbergsalen¸ Nobels väg 1
Program Chairs and Moderators: Dr. Annika Östman Wernerson (KI) and Dr. Jim Maher (MC)
Interprofessional education I
8:30 am
Overview of IPE in the medical programme at
Dr. Riitta Möller (KI)
Karolinska Institutet
8:50
Building interprofessional education at Karolinska
Dr. Sari Ponzer (KI)
Institutet
9:05
Interprofessional education and the Association of
Dr. Tom Viggiano (MC)
American Medical Colleges
9:20
Interprofessional allied health education
Dr. Mike Silber (MC)
9:35
Interprofessional medical education
Dr. Suzanne Norby (MC)
9:50
Break
Interprofessional education II – Session Chairs: Dr. Riitta Möller (KI) and Dr. Jim Maher (MC)
10:20
Interprofessional education at Centre of Clinical
Dr. Ewa Ehrenborg (KI)
Education
Dr. Margaretha Forsberg Larm (KI)
14
10:35
Surgical education and simulation
Dr. T.K. Pandian (MC)
10:50
Surgical resident assessment
Dr. EeeLN Buckarma (MC)
11:05
Interprofessional education in simulator-based team
training
Dr. Li Felländer-Tsai (KI)
11:15
11:30 am –
12:00 pm
12:30
Introduction to the afternoon Karolinska Institutet tour
Open discussion
Dr. Mikael Nilsson (KI)
Cognitive computing and machine learning: Using the
IBM Watson technology to transform research and
clinical data into knowledge solutions
Optional tour to KI University Hospital education units
Phil Lombardo (MC)
Venue: Erling Persson-hall, Aula
Medica
1:45
Interprofessional education training in reality:
 Clinical Training Centre and Clinical Education
Ward/Outpatient Clinic for Education, Solna
Director of Studies - Dr. Mikael Nilsson
 Centre for Advanced Medical Simulation and
Training (CAMST), Huddinge
Director of Studies (postgraduate studies,
surgery) - Dr. Ann Kjellin
Director of Studies (postgraduate studies,
anesthesia) - Cecilia Escher
Director of Studies (professional development)
- Dr. Mini Ruiz
Director of studies in anesthesia and intensive
care (undergraduate education) – Lisbet
Meurling
Pharmacogenomics/Psychology and Psychiatry/Individualized
Medicine, Venue: Air& Fire, Science for Life Laboratory,
Tomtebodavägen 23A
Program Chairs: Dr. Martin Schalling (KI), Dr. Mark Frye (MC), Dr. Stephen Thibodeau (MC), Dr. Olli
Kallioniemi (KI), Dr. Fredrik Wiklund (KI)
8:00 am
Welcome and Overview of the Day
Chairs
8:15
Pharmacogenomic Targets in Major Depression and
Dr. Mark Frye (MC)
Bipolar Disorder
8:45
9:15
9:35
9:55
Pharmacogenomics and pharmaco-epigenomics in drug
response
Right Drug, Right Dose, Right Time – Using Genomic
Data to Individualize Treatment (RIGHT Protocol)
Pharmaco-epidemiological studies of ADHD medication
Break
Dr. Magnus Ingelman-Sundberg
(KI)
Dr. Suzette Bielinski (MC)
Dr. Henrik Larsson (KI)
15
10:15
10:35
10:55
11:15
11:35
12:30 pm
Multidisciplinary education and clinical decision
support to promote pharmacogenomics integration
into the practice
Rare functional mutations in ADME genes of
importance for personalized medicine
Progress in PGX of Antidepressant Treatment Response
through the Pharmacogenomics Research Network and
International Consortium Efforts
Genome-wide association study identifies SESTD1 as a
novel risk gene for lithium responsive bipolar disorder
Closing discussions and future planning
Cognitive computing and machine learning: Using the
IBM Watson technology to transform research and
clinical data into knowledge solutions
Caer Rohrer Vitek (MC)
Dr. Volker Lauschke (KI)
Dr. Joanna Biernacka (MC)
Dr. Sarah Bergen (KI)
All
Phil Lombardo (MC)
Venue: Erling Persson-hall, Aula
Medica
Psychology and Psychiatry, Venue: Air& Fire, Science for Life Laboratory,
Tomtebodavägen 23A
Program Chairs and Moderators: Dr. Martin Schalling (KI) and Dr. Mark Frye (MC)
1:45 pm
Welcome and Overview of Session
Dr. Mark Frye (MC), Dr. Martin
Schalling (KI)
1:50
Prevalence of combined somatic and mental health
Dr. William Bobo (MC)
multimorbidity in a geographically defined American
population: patterns by age, sex, and race/ethnicity
2:10
Genetics and epigenetics of affective disorder
Dr. Catharina Lavebratt (KI), Jiajia
Liu (KI)
2:30
Mortality trends among people with schizophrenia,
Dr. Mika Gissler (KI)
bipolar disorder and depression, Sweden 1987-2010
2:50
Cardiovascular risk management in patients with
Dr. Sven Eriksson (KI)
psychosis
3:10
Break
3:30
3:50
Targeting GRK-3 identifies glia-derived signaling leading
to psychosis
Round table discussion on MC-KI collaboration
Dr. Sophie Erhardt (KI)
Regenerative Medicine, Venue: Room 617, floor 6, Aula Medica, Nobels
väg 6
Program Chairs and Moderators: Dr. Ewa Ellis (KI), Dr. Tony Windebank (MC)
8:40 am
The protein phosphatase Phlpp1 suppresses
Dr. Jennifer Westendorf (MC)
chondrocyte proliferation and is elevated in
osteoarthritic cartilage
9:00
Encapsulated cell biodelivery of nerve growth factor to Dr. Maria Eriksdotter (KI)
the cholinergic basal forebrain of Alzheimer´s disease
patients
16
9:20
9:40
10:00
10:20
10:40
11:00
12:30 pm
1:20-4:00
GDNF-secreting Schwann cells in multichannel OPF+
hydrogel scaffolds promote ascending axonal
regeneration, remyelination and locomotor recovery
following complete spinal cord transection in rats
Treatment of Acute Respiratory Distress Syndrome
(ARDS) with allogeneic mesenchymal stromal cells
Break
Mechano Growth Factor, a Novel Splice Variant of IGF1, Promotes Neurogenesis in the Aging Mouse Brain
Development of clinical grade human pluripotent stem
cells
Wrap-up Discussion and Future Planning
Cognitive computing and machine learning: Using the
IBM Watson technology to transform research and
clinical data into knowledge solutions
One-on-one collaborative discussions, locations tbd
Dr. Nicolas Madigan (MC)
Dr. Oscar Simonson (KI)
Dr. Jun Tang (MC)
Dr. Sergey Rodin (KI)
All
Phil Lombardo (MC)
Venue: Erling Persson-hall, Aula
Medica
Science of Health Care Delivery/Value-Based Health Care, Venue:
Lecture Hall, CMB, Berzelius väg 21
Program Chairs and Moderators: Dr. Jörgen Nordenström (KI) and Dr. Veronique Roger (MC)
8:30-10:00 Innovations in Healthcare Delivery Session I
am
Session chairs:
Dr. Joan Griffin (MC), Dr. Sofia Ernestam (KI)
8:30
Answering Clinical Research Questions using Secondary Dr. Elizabeth Habermann (MC)
Data
8:45
Value-based steering: Experiences from the SVEUS
Jonas Wohlin (KI)
(National Collaboration for value-based compensation
and follow-up of health services) program
9:00
The Ambient Warning and Response Evaluation
Dr. Vitaly Herasevich (MC)
(AWARE): Implementing best practice in the ICU
9:15
The patients personal health system
Sara Riggare (KI)
9:30
The Emergency Department of the 21st Century:
Dr. Kalyan Pasupathy (MC)
Transformational Use of Radio-Frequency Identification
(RFID)
9:45
Panel discussion
10:0010:30
10:3011:45
Break
10:30
Led by:
Dr. Joan Griffin (MC)
Dr. Sofia Ernestam (KI)
Innovations in Healthcare Delivery Session II
Session Chairs:
Dr. Elizabeth Habermann (MC), Dr. Mats Brommels (KI)
Clinical integration in the specialty-hospital: A
Dr. Pamela Mazzocato (KI)
combined clinic for diabetes, heart and kidney disease
Dr. Carl Savage(KI)
17
10:45
11:00
11:15
11:30
11:4512:00
12:30 pm
2:00 – 4:00
6:00 pm
Integrating family caregivers into clinical practice to
improve patient care
The hospital as a venue for med tech innovations
Activity in the trapezius muscle during robotic-assisted
urological laparascopic surgery: A comparison of the
console and assisting surgeon roles
Panel discussion
Karolinska Institutet – Mayo Clinic collaboration
summary
Cognitive computing and machine learning: Using the
IBM Watson technology to transform research and
clinical data into knowledge solutions
Workshop and new Karolinska University Hospital site
visit
2:00 – 2:30 Showroom at NKS
2:45 – 4:00 Workshop – Future Collaboration and next
steps. Venue above NKS Showroom
Dr. Joan Griffin (MC)
Dr. Patrik Hidefjäll (KI)
Dr. Mikael Forsman (KI)
Dr. Susan Hallbeck (MC)
Led by:
Dr. Elizabeth Habermann (MC)
Dr. Mats Brommels (KI)
Dr. Veronique Roger (MC)
Dr. Jörgen Nordenström (KI)
Phil Lombardo (MC)
Venue: Erling Persson-hall, Aula
Medica
Dr. Andreas Ringman Uggla
Topic 1:
Health Care Delivery management – “how to organize
and run a patient-oriented hospital?”
Topic 2: Research – “from theory to practice”
Dinner/cultural event for the Science for Health Care Delivery Group
Neurodegeneration, Site Visit
Program Chairs and Moderators: Dr. Agneta Nordberg (KI), Dr. Prashanthi Vemuri (MC) and Dr. Melissa
Murray (MC)
Information about the transfer will be provided at the Thursday afternoon session
8:10 am
KI bus to Center for Alzheimer Research, Novum
Bus stop at Campus Solna, next to
Nobel Forum, Nobels väg 1.
Instructions from Dr. Nordberg
9-11 am
Visit to Center for Alzheimer Research, Novum
Karolinska University Hospital
(presentations by post-doctoral students, PhD students Huddinge , Novum , entrance 5th
and researchers)
floor close to G elevator.
12:30-1:30 Use of IBM Watson Cognitive Computing Technology to Phil Lombardo (MC)
pm
Match Oncology Patients to Clinical Trials
Venue: Erling Persson-hall, Aula
Medica
2-4 pm
Visit to Aging Center (presentations by post-doctoral
Aging Center, Gävlegatan 16
students, PhD students and researchers)
18
Innovation, Venue: Wangari, Tomtebodavägen 18 A
Program Chairs and Moderators: Dr. Lilian Wikström (KI) and Ms. Julie Henry (MC)
Moderators: Dr. Lilian Wikström (KI) and Ms. Julie Henry (MC)
9:00 am
Welcome
Julie Henry (MC)
Dr. Lilian Wikström (KIAB)
9:10
Innovation strategy at KI
Dr. Alexander Von Gabain (KI)
9:30
Innovation support at Mayo Clinic
Julie Henry (MC)
9:50
Commercializing innovation at KI
Dr. Christian Krog- Jensen (KIAB)
10:10
Break
10:30
Mayo Clinic Office of Invention and Translation to
Practice
Moderators: Dr. Carol Tishelman (KI) and Ms. Julie Henry (MC)
10:50
Innovation partnerships
11:10
Center for Innovation and its role at Mayo Clinic
11:30
Innovation project - Rethinking the role of technology:
Supporting collaboration with patients across the
continuum of care
12:30 pm
Cognitive computing and machine learning: Using the
IBM Watson technology to transform research and
clinical data into knowledge solutions
1:15-4 pm
Individual meetings for collaborative discussions
Dr. Andrew Badley (MC)
Stefan Vlachos (KS)
Dr. Douglas Wood (MC)
Marnie Meylor (MC)
Phil Lombardo (MC)
Venue: Erling Persson-hall, Aula
Medica
All
Cardio-Oncology, Venue: Radiumhemmet P1:01, (entrance
Radiumhemmet, 1st floor), Clinic of Oncology, Karolinska University
Hospital
Moderators: Dr. Cecilia Linde (KI) and Dr. Joerg Herrman (MC)
8:30 am
9:15
9:50
10:15
10:30
10:50
Cardio-Oncology: The current landscape
Caridotoxicity and breast cancer
Radiotherapy- induced cardiotoxicity
Break
Registry based results: Incidence of cardiotoxicity
among breast cancer treated women in Sweden
Practical guidance on management for day-to-day
practice
11:45
The current gaps and potential future projects
12:30 pm
Cognitive computing and machine learning: Using the
IBM Watson technology to transform research and
clinical data into knowledge solutions
Dr. Joerg Herrmann (MC)
Dr. Jonas Bergh (KI/KS)
Dr. Joerg Herrmann (MC)
Dr. Andri Papakonstantinou
(KI/KS)
Dr. Agneta Månsson Broberg
(KI/KS)
Dr. Joerg Herrmann (MC)
Dr. Elham Hedayati (KI/KS)
Dr. Joerg Herrmann (MC)
Phil Lombardo (MC)
Venue: Erling Persson-hall, Aula
Medica
19
Posters
Cancer




Protein Kinase D-mediated phosphorylation at serine 448 regulates the lipid kinase activity of
Phosphatidylinositol-4-phosphate 5-kinase type-l ɣ - Nisha Durand (MC)
PUB (Pile-Up Based Backfill) Pipeline for Identification of Sub-Clonal Mutations in Tumor DNA
Sequencing Data: Identification of mTOR Activating Mutations in Breast Tumor Sequencing Data
- Dr. Yan Asmann (MC)
Investigating Novel Therapies for Platinum-Resistant Ovarian Cancer - Rachel Hurley (MC)
Organotypic Tumor Tissue Slice Cultures: Ex-Vivo Methods for Individualized Cancer Treatment
Screening – Dr. Tommy Ivanics (MC)
Cardiovascular Diseases



Intimal smooth muscle cells are vascular tissue specific innate immune effector cell –
Dr. Xintong Jiang (KI)
The pathological role of iron in aortic valve stenosis – Dr. Andres Laguna-Fernandez (KI)
Systemic 5-lipoxygenase activation in aortic valve stenosis – Jasmin Barimani (KI)
Diabetes and Metabolism







Unleashing the Demons of Behavior Change Leads to Positive Outcomes – Kim Louise Edens
(MC) and Dr. Todd Wade (MC)
Low BMI, Increased Self-Reported Health Status, and High Prevalence of Healthy Behaviors
among 5,433 Participants in the American Birkebeiner Ski Race – Dr. Paul Anderson (MC)
Use of electronic medical record to assess outcomes of comprehensive lifestyle intervention for
obesity treatment – Dr. Teresa Jensen (MC)
A Novel Triple Tracer Approach to Assess Postprandial Protein Turnover – Dr. Antoinetta Moran
(University of Minnesota)
Senescent Cell Clearance as Therapy for Type II Diabetes: Studies in Diet-Induced Obese Mice Allyson Palmer (MC)
JAK Inhibition Alleviates the Cellular Senescence-Associated Secretory Phenotype and Improves
Multiple Phenotypes in Old Mice – Dr. Tamar Tchkonia (MC)
Future of Exercise Medicine Clinics and Clinical Exercise Physiologists in Healthcare – Dr. Daniel
K. Halvorsen (University of Minnesota)
Education




Supporting the formation and progress of multidisciplinary research teams through online
assessment and dissemination of team science education – Dr. Heather Billings (MC)
Education scholarship – Dr. Katrin Frimannsdottir (MC)
Mayo-KI shared course - Karen Weavers (MC)
Education Science in Mayo Clinic College of Medicine. Education publications 2009-2014 – Dr.
Katrin Frimannsdottir (MC)
20











To facilitate interprofessional learning (IPL) at the academic health care centers in Stockholm
County, Sweden – Dr. Maria Kvarnström, Margaretha Risén, Ulla Thörnblom (KI)
Establishing a web based discussion forum for interprofessional education in Stockholm County
– Dr. Maria Kvarnström¸ Margaretha Risén, Ulla Thörnblom, Monica Östberg (KI)
Teaching dialogues across professional boundries for improved quality of clinical education Margaretha Forsberg Larm, Dr. Ewa Ehrenborg, Dr. Michel Silvestri, Dr. Annika Wernerson, Dr.
Anna Kiessling (KI)
Interprofessional education for better health -strategic organization and development – Dr. Eva
Broberger, Lena Engqvist Boman, Margaretha Forsberg Larm, Dr. Lars-Arne Haldosen, Carina
Gezelius (KI)
Team building training - facilitating interprofessional teams - a continuing process for quality of
care - Dr. Uffe Hylin, Marie Sjöstedt, Margaretha Forsberg Larm, Dr. Sari Ponzer (KI)
Interprofessional training in the operating theatre - Dr. Uffe Hylin, Dr. Charlotta Olivekrona,
Sofia Kärrlander, Christina Jonsson, Dr. Hans Törnkvist, Dr. Christer Svensén (KI)
Professional Behavior ; Validation of a new instrument in clinical situations - Margaretha
Forsberg Larm, Marie Sjöstedt, Dr. Sari Ponzer (KI)
Hall of Mirrors: Reflecting on reflections during an interprofessional placement - Constantina
Lomi, Rene Ballnus (KI)
Validation of the Interdisciplinary Education Perception Scale (IEPS) : A Swedish translated
version - Dr. Sari Ponzer, Dr. Hanna Lachmann, Marie Sjöstedt, Dr. Susanne Kalén (KI)
Introduction to interprofessional experience ; Learning together on an Interprofessional Training
Ward - Margaretha Forsberg Larm, Cecilia Bäckman, Dr. Uffe Hylin, Dr. Hanna Lachmann,
Marie Sjöstedt (KI)
Patients´ Voice At The Interprofessional Student Ward - Anders Nilsson, Margaretha Forsberg
Larm (KI)
Infectious Diseases

IgG-omics, a window into human blood proteome with clinical implications – Dr. Susanna
Lundström (KI)
Neurodegeneration





Role of Butyrylcholinesterase-K genotype in Alzheimer’s disease and Lewy body dementia Swetha Vijayaraghavan (KI)
Regional distribution and binding properties of 3H-THK5117 in AD autopsy brain – Dr. Laetitia
Lemoine (KI)
Molecular modeling studies of Choline Acetyltransferase inhibitors as potential PET probes – Dr.
Rajnish Kumar (KI)
Plasma Choline acetyltransferase in patients with cognitive impairment and AD - Azadeh Karami
(KI)
Identification of proteins involved in astrocytic activation in GRK3 -/- mice - Xicong Liu (KI)
21
Psychiatry and Psychology








Alcohol Use Disorders, Treatment - Dr. Nitya Jayaram-Lindström (KI)
Excitatory amino acid transporter 2 (EAAT2) Promoter Methylation is Differentially Expressed in
Bipolar Disorder with and without Comorbid Addiction - Dr. Mark Frye (MC)
Economic Impact of Suicidality in Manic Patients with Depressive Features – a Swedish Registry
Study – Dr. Jonas Eberhard (Lund University & Lundbeck)
Ketamine Reduces Prefrontal Kynurenine Levels and Increases mTOR Signaling in an Animal
Model of Treatment Resistant Depression –Blair Price (MC)
Fluoxetine-resistant depression-like behavior in mice is preceded by impaired circadian
entrainment – Dr. Stefan Spulber (KI)
Dual LPS injections induce disparate changes in the kynurenine pathway versus a single injection
– Anthi Faka (KI)
Excitatory amino acid transporter 2 (EAAT2) Promoter Methylation is Differentially Expressed in
Bipolar Disorder with and without Comorbid Addiction – Dr. Marin Veldic
Perceptions of psychopathy among clinicians and laypeople in Sweden and the U.S – Dr.
Karolina Sörman (KI)
Regenerative Medicine






A Dose Escalation Safety Trial on Intrathecal Delivery of Autologous Fat-derived Mesenchymal
Stromal Cells in Amyotrophic Lateral Sclerosis – Dr. Nathan Staff (MC)
Impaired regenerative capacity in premature aging – Dr. Mi-Hyeon Jang (MC)
Drosophila melanogaster as a Model for Studying Chemotherapy Induced Neurotoxicity –
Dr. Anthony Windebank (MC)
Overcoming Critical Size Nerve Defect: Conditioning of Nerve Conduits - Dr. Anthony
Windebank (MC)
Mesenchymal Stem Cells Induce Neuron Recovery and Improve Limb Function Following
Hemorrhagic Stroke - Dr. Abba Zubair (MC)
Correction of Metabolic Liver Disease and Acute Liver Failure by the Transplantation of Human
Amnion Epithelial Stem Cells – Dr. Roberto Gramignoli (KI)
Science of Health Care Delivery/Value Based Health Care





Identification of the adult septic patient in the prehospital setting; a comparison between two
screening tools and clinical judgement; The association between vital signs and mortality among
100,000 unselected ED patients – Dr. Lisa Kurland (KI)
Application of innovative motion tracking wearables for measuring intraoperative surgeon
workload: A multi-center study on robotic prostatectomies - Dr. Susan Hallbeck (MC) and
Dr. Magnus Kjellman (KI)
Outside the Sterile Field: Evaluating and Improving Surgical Techniques for Optimal Health Care
Delivery in Surgery - Dr. Bethany Lowndes (MC)
Application of innovative motion tracking wearables for measuring intraoperative surgeon
workload: A multi-center study on robotic prostatectomies - Dr. Denny Yu (MC)
Human factors examination of operating room (OR) traffic and surgical team transformation Renaldo Blocker (MC)
22
Autoimmune Disorders


Atherosclerosis in Systemic Lupus Erythematosus (SLE) and Controls, -An Analysis of SLE
Subgroups – Dr. Elisabet Svenungsson (KI)
Single-cell analysis of the citrullinated self-antigen-specific B cell repertoire in rheumatoid
arthritis – Dr. Philip Titcombe (KI)
23
Researchers Seeking Collaborators
Name
Sujata Lalit Kumar
[email protected]
Mark Zobitz
[email protected]
Phil Lombardo
[email protected]
Aaron Johnson
[email protected]
Aman Anand
[email protected]
Tommy Ivanics
[email protected]
Keith Knutson
Seeking a collaborator with a scientific interest in…
 Infertility, assisted reproduction, gynaecological disorders
and reproductive surgery
 Sharing of best practices
 Administration of research space
 Natural language processing
 cognitive computing/machine learning technologies
 Neuroimmunology
 Neuro-oncology
 Proton and functional imaging and nanotechnology
 Organotypic ex-vivo tissue culture
 Tumor immunology
[email protected]
Raoul Tibes
[email protected]
Manuel Patarroyo
[email protected]
Klas Wiman
[email protected]
Irene Selle
[email protected]
Natalia V Rivera
[email protected]
Xintong Jiang
[email protected]
Katrin Frimannsdottir
[email protected]
Jennifer Westendorf
[email protected]
Abba Zubair
[email protected]
Aman Anand
[email protected]
 Hypomethylating agent failure in AML and MDS
 Tumor invasion and metastasis, adhesion/matrix biology
 Novel cancer therapy
 Education data warehousing
 Looking for collaborators to join meta-analysis genomewide association study on sarcoidosis phenotypes, and
other sarcoidosis genetic-related projects
 Atherosclerosis and arteritis, immune mechanisms
 Program evaluation in education
 Osteoarthritis, bone, cartilage
 Mechansim of stem cell induce neuroregeneration
 Oncology-pathology colleagues to model the charge
particle interactions at the nanometer scale with biofunctional materials
 Muskardin/Inflammatory arthritis precision medicine
Theresa Wampler
[email protected]
Matthew Robinson
 Skeletal muscle mitophagy and insulin resistance
[email protected]
Michael Jensen
 Obesity
[email protected]
24
Kerstin Brismar
[email protected]
Italo Masiello
[email protected]
Olle Kämpe
[email protected]
Anna Lindstrand
[email protected]
Lisa Kurland
[email protected]
Tamas Ordog
[email protected]
Sokratis Nifakos
[email protected]
Carina Ursing
[email protected]
[email protected]
Örjan Smedby
[email protected]
James Kirkland
[email protected]
Elizabeth B. Habermann
habermann.elizabeth @mayo.edu
Heather Billings
[email protected]
William V. Bobo
[email protected]
Caer Vitek
[email protected]
Suzette J. Bielinski
[email protected]
Rodrigo Moreno
[email protected]
Peter Daneryd
[email protected]
Timothy Beebe
[email protected]
Anthony Windebank
 Identifying pat at risk for type 2 DM and intervention
studies
 Medical education, interprofessional education and
simulation
 Organ-specific autoimmune disorders
 Genetics and body weight
 Emergency medicine, esp. sepsis identification, quality
measures of emergency care, education
 Epigenomics/epigenetics, gastrointestinal stromal tumors,
enteric neuroscience, neuron specification, diabetes
 Software and network engineers
 Pedagogy and diabetes and pregnancy
 Medical imaging, post-processing (segmentation of
anatomic structures, volume measurements of e.g.
tumors, quantification of vascular disease, quantitative
structure description of e.g. trabecular bone)
 Aging, cellular senescence
 Surgical outcomes research
 Faculty development, team science, mentoring, adult
education and online and blended instructional design,
delivery and assessment
 Psychiatric epidemiology and psychiatric
pharmacoepidemiology
 Implementation and effectiveness of pharmacogenomic
alerts in the electronic medical record
 Education of providers (physicians, pharmacists, genetic
counselors, nurses, etc.) and patients regarding
individualized/precision medicine
 Cardiovascular genetics, pharmacogenomics
 Medical image analysis, tensor-based processing,
osteoporosis, CVD
 Health policy, healthcare system comparison, leadership
issues, cancer care organization and management, care
process development
 Patient reported outcomes measurement
 Regenerative approaches for peripheral nerve and spinal
25
[email protected]
Juan Jesus Carrero
[email protected]
Martin Schalling
[email protected]
Vilija Oke
[email protected]
Natalia Landázuri
[email protected]
Erik Berglund
[email protected]
Clas Rehnberg
[email protected]
Johan Thor
[email protected] [email protected]
Carl Savage
[email protected]
Karolina Kublickiene
[email protected]
Joan Griffin
[email protected]
Renaldo Blocker
[email protected]
Kalyan Pasupathy
[email protected]
Teresa Daraio
[email protected]
Kenneth Caidahl
[email protected]
Ivan Nalvarte
[email protected]
cord repair
 Renal disease/cardiovascular epidemiology
 Psychiatric genetics and epigenetics, eating disorders
biology, viral causes of obesity and metabolic disease
 Autoimmunity
 Scientific interest in brain tumors, stem cells and cancer
stem cells
 Transplantation tolerance
 Economics of health system (structure, reimbursement,
private/public mix)
 Quality measurement for clinical quality and value
improvement
 Leadership development, business model development
and costing for value-based health care
 Implementation of gender dimensions in education and
research towards innovation; and cardiovascular health in
women at reproductive age and after menopause
 Impact of caregiving and family on disease management,
patient outcomes and quality of care
 Human factors and ergonomics/healthcare systems
engineering (specific interest in teamwork/transition of
care, workload, cognitive ergonomics)
 Health care systems engineering
 Mechanisms of insulin exocytosis
 Vascular function
 Hormone signaling during CNS development:
Consequences for affective spectrum disorders later in life