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Complete Article
EARLY SUCCESS: After Josie nearly tore off her right hind hoof in a 1992 pasture accident, she was given to Ric Redden, DVM, of the International Equine Podiatry Center in Versailles, Kentucky. Since then, the little grade mare has been instrumental to Redden’s pioneering work in equine amputations and prosthetics. Josie is shown here, about five months after her injury, just before being turned out for the first time with her new prosthetic limb. Watching the mare gallop in her pasture that day was “the most exhilarating experience of my professional career,” says Redden. 56 E Q U U S 3 2 4 AN ARTIFICIAL LEG TO STAND ON o c t o b e r 2 0 0 4 equus c Advances in amputation and prosthetic devices offer a viable alternative to euthanasia when a horse’s limb is damaged beyond repair. o c t o b e r 2 0 0 4 doesn’t suit a horse and requiring heroic care. Not so, say the surgeons who have been working to modify and improve the procedure. “It’s an option for owners, and one I wish more would consider,” says Ted Vlahos, DVM, an equine practitioner from Sheridan, Wyoming. “But they have to know what’s in store for them and their horse if they make that choice. This isn’t a minor procedure. It’s no more benign than a person having his leg amputated.” In short: Removing any portion of a horse’s limb and replacing it with a prosthesis requires a significant commitment of money and time and no small measure of personal fortitude. There are ample opportunities for catastrophic complications, and a horse with a prosthetic limb can never be ridden. He can, however, maintain a reasonably good quality of life. By Joseph and Carol Berke with Christine Barakat Likely candidates? Horses who experience sudden catastrophic injuries and those in the early stages of a chronic condition are the best candidates for amputation and prosthetic repair. “A horse who suffers a sudden, serious breakdown is usually an athletic horse with nothing else wrong with him,” Vlahos says. “He’s in pretty good physical condition, aside from the injury itself, and typically, he has three other very good legs.” Such a horse, according to Vlahos, usually has the physical reserves to handle not only surgery, but the prolonged recovery period and adaptation to a new way of life. Ric Redden, DVM, of the International Equine Podiatry Center in Versailles, Kentucky, agrees: “An athlete that shatters his cannon bone, totally destroying the blood supply to the lower limb, would be the perfect candidate because his body and mind are quite healthy.” In contrast, a horse who has lived for months or years with laminitis or severe arthritis isn’t going PHOTOS COURTESY, RIC REDDEN, DVM T he past two decades have seen remarkable progress in equine orthopedics. Improvements in surgical techniques and equipment as well as breakthroughs in drug therapy are preserving the lives of horses whose leg injuries once might have been seen as so severe that euthanasia was the only option. Yet for all that can be done to repair and rehabilitate equine limbs, some equine afflictions still seem beyond the reach of medical treatment. Aggressive arthritis can quickly cripple a oncehealthy athlete. A bone-eating infection can destroy a joint in days. And laminitis remains a baffling, painful and deadly condition. How can horses so stricken ever return to comfortable and relatively productive lives? Largely through the efforts of a small group of veterinary surgeons, amputation and prosthetic limbs are beginning to emerge as a reasonable option. “Horses can live quite happily with a prosthetic limb for years and years, running, bucking, breeding and acting like a horse in every way,” says Barrie Grant, DVM, of San Luis Rey Equine Clinic in Bonsall, California. An equine surgeon, Grant has performed more than 25 amputations, and one of his patients has had a prosthetic limb for 20 years. “We’ve conquered many of the problems we faced in the past and continue to make breakthroughs,” he says. “In fact, one of the biggest hurdles we still face is convincing people that it can be done.” Historically, horsemen have regarded amputation and prosthetic repair as extreme options of last resort that, at best, offer only marginal success. It is commonly believed that a horse with an amputated limb will develop laminitis in his opposite “good” leg—the result of its having to bear more than its fair share of weight—or that he will hobble pathetically for a few years, living a life that E Q U U S 3 2 4 57 techniques An evolving science c FOR MORE INFORMATION: To read an account of an earlier effort to fit a horse with a prosthetic limb, go to “Boitron: The Horse With the ‘Bionic’ Leg,” EQUUS 100. 58 E Q U U S 3 2 4 The equine limb is a marvel of engineering. A column of bone, sinew and skin no larger than six inches in diameter, it supports thousands of pounds of force at high speed, absorbing shock and adapting to footing that can change in an instant. Replacing a horse’s leg with a device that is equally versatile is not yet possible, but prosthetists—the professionals who make artificial limbs for people and animals—work to incorporate the latest technological advances into devices that do more than simply offer support. “The idea is to mimic the mechanics of the leg as much as possible,” says Barrie Grant, DVM, of San Luis Rey Equine Clinic in Bonsall, California. “It’s important that a device be able to bear the weight of the horse and have some shock absorption, which cuts down on pressure on the stump.” The more comfortable the prosthesis is, Grant continues, the more weight the horse will put on it, meaning the less stress the opposite limb will have to bear. Virtually all of the prosthetists who work with equine surgeons construct artificial limbs primarily for people. “The real advances in prosthetic limbs, such as spring-loaded devices, are being made in the human field,” Grant explains. “And a good prosthetist will try to incorporate them into an equine device.” The first step in creating an equine prosthesis is to make a cast or mold of the stump so that a socket can be custom built. Fit is very important for the comfort of the horse and the health of the stump. Most equine prostheses are made from various combinations of carbon graphite, fiberglass, stainless steel and various plastics. They usually are suspended from the joint above the amputation site and secured with straps and/or harness systems. Ted Vlahos, DVM, of Sheridan, Wyoming, has worked with a local prosthetist to develop an equine prosthesis that is intended to be more comfortable for the horse and less complicated for the owner to remove and replace. “Our boot has clamps to hold it in place, much like a ski boot,” Vlahos says. “We think it’s much easier to work with.” to be in the best physical condition. “In those cases, the horse commonly has overused the good limb; it’s been bearing more than its share of the weight for a while,” Vlahos says. Immediately after amputation that good leg is under even more stress, which can have disastrous consequences. “When horses founder in the opposite leg after amputation, it’s typically because that leg was already damaged from overuse,” Vlahos continues. “That’s one of the biggest reasons why the decision to amputate needs to be made sooner in the course of chronic conditions, rather than later. “Amputation is still a salvage procedure— something you do when there is no other way to save the horse. But waiting too long to reach that decision can really reduce the odds of success.” Vlahos adds that since surgeons have begun amputating limbs earlier in the progression of chronic conditions, the incidence of laminitis in the opposite leg--one of the more common complications of the procedure--has dropped dramatically. Several additional factors contribute to the success of an amputation and prosthetic repair: ■ The location of the amputation: In general, hind-limb amputations are less taxing for a horse because his rear legs bear a smaller percentage of his overall weight. In addition, the lower on the leg an amputation is performed, the better the likely outcome because more of the limb’s joints remain intact. That makes it easier for the horse to maintain his natural gait and to get up and down. Amputations above the knee or hock currently aren’t feasible. “But we will eventually get there,” Redden says. ■ The horse’s breed and size: “The best breeds for the procedure are the smaller, lighter breeds,” says Gayle Trotter, DVM, an orthopedist at Colorado State University. “The larger breeds are more vulnerable to breakdown of the soft tissue in the support limb while they are adapting to the prosthesis.” ■ The horse’s attitude: “Those who have longterm success with a prosthesis are able to adapt quickly to rapidly changing situations and stimuli,” says Grant. For instance, periodically in the months following surgery, the horse will be positioned in a hanging sling for cast changes and prosthesis adjustments. He’ll also have to learn how to lie down, stand up and move with a prosthetic limb. “Unfortunately, it’s tough to know how a horse is going to adapt until you’re actually in the situation,” says Grant. ■ The owner’s wherewithal: The initial surgery o c t o b e r 2 0 0 4 and hospital stay will cost between $10,000 and $15,000 and the prosthesis will add another $5,000. “Beyond the costs, there is an enormous commitment of time that’s required,” says Vlahos. “You will never sell this horse and he will require hands-on care every day for the rest of his life.” Perhaps Grant sums it up best: “If you’re not going to go into it fully committed and prepared to see it through for years and years—physically and emotionally as well as financially—don’t do it at all. It’s not fair to the horse.” The details of surgery Before an amputation is performed, the horse must be medically stable, particularly in the case of an acute injury. “I don’t think it’s a great idea to rush [a prosthesis candidate] from the racetrack to surgery, even if you know that’s where you’ll end up,” says Grant. “It’s much smarter to apply a cast and give the horse a day or two to stabilize while you get yourself organized for what lies ahead.” Grant uses that time to condition the horse to the sling that will become a critical part of the recovery process. With the injured limb stabilized in a full-length splint or cast, the horse is lightly sedated and placed in the sling for one or two short MODEL PATIENT: Twelve years after losing her hind hoof in an accident, Josie is “thriving on very little maintenance, beyond replacing her artificial leg whenever she wears one out,” reports Ric Redden, DVM. “She is turned out full-time with other horses and has been since she got her very first prosthetic.” Josie is now wearing her fourth artificial limb (above), which Redden describes as one of his simpler designs. o c t o b e r 2 0 0 4 E Q U U S 3 2 4 59 STATE OF THE ART: After an amputation was performed on a Thoroughbred mare named Callie, X-ray images show that the coffin bone has been removed. For protection and comfort, frog tissue was removed from Callie’s remaining hooves and grafted onto her stump. The frog tissue, which eventually hardens, continues to grow and requires periodic trimming just as it would on a normal hoof. Supported by a sling, Callie has her prosthetic limb fitted. The sling plays a critical role in the recuperation of an equine amputee, providing support immediately after surgery and later on in the recovery period when medical treatment is necessary or adjustments are made to the prosthesis. 60 E Q U U S 3 2 4 sessions. These practice runs not only accustom the horse to the sling, says Grant, they provide valuable insights into how accepting the patient will be of the changes and stresses that lie ahead. On the day of surgery, the horse is placed under general anesthesia and positioned on either his side (lateral recumbency) or his back (dorsal recumbency). To determine how much of the limb will be removed, the surgeon examines radiographs of the area and visually inspects the tissues to determine which are healthy and which are dead or dying. “You want to leave only perfectly healthy tissue and tissue that has ample blood flow,” says Grant. Typically, he removes the leg an inch or so above a damaged joint. For an injury that is elsewhere on the lower leg, he amputates an inch or so below the next highest joint to minimize stress on the remaining bone. Prior to the amputation, the surgeon inserts two metal pins in the bone near the site. Technically known as transfixation pins, they will transfer the horse’s weight around the surgical site to a temporary prosthesis, allowing him to walk immediately after surgery without placing weight on the healing stump. The pins are placed at a 30-degree angle, a recent modification that has improved the success rate of the procedure. “Pins used to be placed in the bone parallel to the ground, and fractures at the pin site during recovery from anesthesia used to be a common complication,” says Vlahos. But when surgeons began placing the pins at an angle, the incidence of fractures dropped dramatically. “There is simply less concentration of stress on the bone when the pins are placed at 30-degree angles,” Vlahos explains. With the pins in place, the amputation begins. Typically, the surgeon first creates an elliptical or semicircular flap of tissue on the fleshy back side of the limb. This flap includes skin, subcutaneous fat and tissue and, if it is healthy, the stump of the flexor tendon. Later, this flap will be pulled over the bone end and sutured to the front of the limb to create a covering. As the operation proceeds, the surgeon isolates and severs nerves, using a cryosurgery probe to freeze the endings, a technique that will minimize pain following surgery. The suspensory ligament is cut and then the bone. The end is smoothed and rounded and covered with wax to reduce bleeding. The next step involves the most recent—and what some surgeons consider the most important—innovation in equine amputation: frog grafting and transplantation. Developed by Redden, the technique involves taking healthy frog tissue from o c t o b e r 2 0 0 4 THE REPLACEMENTS: Grafted frog tissue does require periodic attention: It grows just as it does on the hoof, so it must be trimmed regularly to ensure the prosthesis’ fit. Once the amputation is complete, the surgeon applies a fiberglass cast that incorporates the temporary prosthesis attached to the transfixation pins. The horse is then placed in the all-important sling to recover from anesthesia. “Our biggest complication used to be fracture of the limb during recovery,” says Vlahos. “However, we’ve all but eliminated the incidence of that with angular pin placement and sling recovery.” If all goes well, the horse bears weight on the prosthesis immediately following surgery and is able to walk comfortably. “I’ve had experiences with horses who lived with extremely painful conditions for months before amputation,” says Grant. “They wake up sore after surgery, but the deep gnawing pain is gone and you can almost see the relief on their faces.” Initially, a horse who has undergone an amputation wears a temporary prosthesis until the stump heals. Young horses, however, may go through several temporary artificial limbs as they grow and develop. When healing and/or growth is complete, the horse is fitted with a permanent prosthesis (below), the exact design of which varies from case to case. COURTESY, TED VLAHOS, DVM (TOP) Recovery and aftercare 62 E Q U U S 3 2 4 the patient and grafting it into the stump either at the time of surgery or, in some cases, one or two weeks afterward. As the frog tissue grows, it forms what Redden describes as “a wonderful, tough, resilient material” that protects the bottom of the stump. Prior to frog grafting, the amount of muscle and tissue that remained after surgery wasn’t always sufficient to adequately shield the bone end. The result was painful pressure and trauma that eventually necessitated euthanasia. Complete recovery from amputation surgery can take anywhere from six months to a year, during which time the horse likely will live at the equine hospital for intensive care and management. The fiberglass cast and temporary prosthesis will be refitted at least once, and possibly several times, as the stump heals. Each cast change requires that the horse be sedated and placed in a sling. The pins are removed once healing is well under way, which takes between eight and 12 weeks. The horse then will bear weight directly on the temporary prosthesis. In the best cases, the horse is fitted for a permanent prosthesis three months after the pins are removed; six months following surgery, he can be turned out in a small enclosure with quiet companions. During the recovery period, any number of complications can arise, from infections to stump pain to pressure sores. Some horses, says Grant, never learn how to lie down with an artificial limb. “If you get a horse that won’t lie down, it can be a big problem,” he says. “It puts a lot of stress on all the limbs. I’d love to teach one to lie down on command before an amputation. I think that might avoid some of those problems.” Vlahos says he isn’t comfortable labeling a procedure a success until a year has passed. “I think that if we can get a horse through the first year without complications, then there’s no reason to think he can’t live out his life comfortably,” he says. Once an amputee goes home, his daily care isn’t complicated, but it does require extreme diligence and commitment. Most prosthetic limbs have to be o c t o b e r 2 0 0 4 case study To save a filly c When complications from a contracted tendon destroyed the circulation in his 3week-old filly’s lower leg, Jim Perkins thought all was lost. “The hoof just came off and a few days later, the fetlock joint fell away,” he says. The Amarillo, Texas, horseman worked to prevent the stump from becoming infected. He also devised a crude prosthesis for the foal, using PVC pipe. “She was getting around on the prosthesis, but I could tell she was in pain,” Perkins says. “I wanted to give her a chance, but I was preparing to make the tough decision to put her down.” The filly’s grandmother was a champion cutting mare and both Perkins and his wife had hoped that the youngster someday would be an important addition to their large breeding program. They understood that their plans for her might 64 E Q U U S 3 2 4 never be realized, but their emotional attachment to her made it extremely difficult for them to consider euthanasia. “To my wife and myself, these horses are like children,” Perkins says. “We brought her into this world, so we feel it’s our responsibility to take care of her while she’s here and do everything we can to help and not give up.” Then the Perkins’ daughter saw a televised segment about veterinarian Ted Vlahos on “Good Morning America” and immediately called her father. Vlahos is one of a few surgeons in the United States who outfits horses with prosthetic limbs. Within days, the filly and her dam were on a trailer for the 900-mile trip to Vlahos’ clinic in Sheridan, Wyoming. Amputation wasn’t necessary, but Vlahos performed skin and frog grafts to fashion a protective stump, and he put pins in place to support the filly’s bad leg on a temporary prosthetic while the grafts healed. After surgery, the foal stood without pain for the first time in her life, and within days she was running and playing with her dam. The filly was weaned at Vlahos’ clinic when she was 5 months old and returned home at 7 months. She was named Dulces Vlahos, says Perkins, because “When it was time to name her, Dr. Vlahos had had her longer than we did.” Now on her second prosthesis—she will have several more made as she grows—the filly lives a typically equine existence on the Perkins’ ranch. “She is turned out with other horses and can trot and gallop and will even kick at you if she puts her mind to it,” says Connie Perkins. “She is just thriving.” The Perkins know that Dulces will never be a “normal” horse and will always require special care. “I don’t have a problem taking care of this little one every day for the next 25 years,” says Perkins, who has spent nearly $80,000 on all the combined veterinary expenses for Dulces and about $4,000 more for each prosthetic limb. “There’s no question in my mind that she is worth it.” o c t o b e r 2 0 0 4 removed daily or every other day so the stump and its protective sock can be cleaned. The stump also needs to be inspected for signs of trauma or pressure. “You have to be vigilant and catch things the minute they appear,” says Vlahos. “It’s a daily commitment and one you might not be comfortable leaving with anyone else. Vacations could be difficult.” Prosthetic devices typically require padding at the stump, and most owners quickly become skilled at choosing and arranging the cushioning material, says Grant. “We learn a lot from owners about padding,” he says. “They’ve experimented and found what works best for their horse.” As for the other aspects of routine management and care, not much will change for a horse with a prosthetic limb. He may require the use of a sling to support his weight and aid his balance when he’s trimmed and shod. Otherwise, “these horses can be turned o c t o b e r 2 0 0 4 out in a quiet herd,” says Grant. “They can buck and play and act like a horse.” They cannot, however, be ridden. “I would never recommend that anyone try to ride a horse with a prosthetic limb,” says Vlahos. “That would be unsafe for the horse and the rider.” Most amputees are used for breeding, although many surgeons recommend artificial insemination whenever possible, to reduce the risk of injury. he practitioners who perform amputations and prosthetic fittings are often reluctant to quote percentages regarding success rates and average life span following the procedure. “Each case is so incredibly different,” says Grant. “You really can’t say that what happened with one horse is going to happen with the next—good or bad.” More hard and fast scientific answers may be available soon, though, says Vlahos, who helped author T a large retrospective study with “encouraging results.” The study has been accepted by a veterinary journal and is awaiting publication. What is available now, however, is an honest portrayal of what lies ahead for the horse as well as his owner. “I’m as enthusiastic as anyone about the procedure,” says Vlahos. “It’s a very, very useful and feasible option that can save the life of a horse. But there has to be a reality check. It won’t work for every horse, there is plenty of potential for complications and it is a huge commitment for the rest of the horse’s life that not every owner can, or wants to, make.” Nevertheless, the advances in amputation technique and prosthetic development now being made offer a viable alternative and perhaps a new source of hope to those who would give just about anything to see a beloved and severely injured horse romp in the paddock once again. E Q U U S 3 2 4 65