Department of Medicine Annual Report 2015

Transcription

Department of Medicine
Annual Report 2015
OUR WORK IS REDEFINING MEDICINE.
Chairman’s Message
I am delighted to present the Department of Medicine FY 15 Annual Report. This year’s theme focuses on the impact that our work
has had on the tripartite mission within and outside the University of Chicago. Through our advanced investigations, teamwork
and data-driven technology, our quest for new medical knowledge has led to innovative translational and clinical trials that have
advanced therapies and redefined how we practice medicine. Our clinicians, researchers and educators are dedicated to solving
complex medical problems that integrate novel scientific findings, and to training the next generation of physicians and scientists
who will carry on our legacy of discovery and exceptional patient care.
Some examples of our impactful work over the past year include:
•Created new big data resources to enable scientists to examine •Created a new Heart and Vascular Center (Liao)
the underlying genomics of many different human tissues and
•Successfully matched our graduating residents into many of
cells, and provide new insights into how genomic variants
the most competitive and premier fellowship programs in
control genes in different tissues, and predispose people to
the country, including 12 who continued their training at the
diseases such as cancer, heart disease and diabetes (Nicolae,
University of Chicago
Grossman, Stranger)
Other highlights include:
•Discovered that a high-fat diet can trigger inflammation in the
intestine, altering the gut microbiome in ways that can lead to •Two new chief appointments: Arlene Chapman, MD, chief of
the Section of Nephrology, and Ronald Cohen, MD, chief of
autoimmune diseases (Chang), and determined the impact of
the Section of Adult and Pediatric Endocrinology, Diabetes
insufficient sleep on obesity and diabetes (Chang, Tasali)
and Metabolism
•Developed a new computational method with the potential to
identify gene targets for therapeutic applications faster and •Named professorship for Wendy Stock, MD—Anjuli Seth
Nayak Professor in Leukemia
with greater accuracy than traditional methods (Nicolae, Im)
•National and international recognition for many impactful
•Created a Genomic Prescribing System (GPS) that allows
physicians to take a patient’s genetic information into account individual contributions, including health economics and public
policy (David Meltzer, MD, PhD), leadership in internal medicine
when prescribing medical treatments and utilized it to help
(Marshall Chin, MD), global health (Olufunmilayo Olopade, MD),
physicians choose more effective cardiovascular medicines
and ethics (Mark Siegler, MD, and Monica Peek, MD)
(O’Donnell, Ratain)
•Determined the effectiveness of lifestyle interventions in
a community-based setting to prevent or delay the onset
of diabetes in at-risk populations (Burnet, Chin, Huang,
Meltzer, Chou)
•Provided new insights into immunotherapy for the treatment
of head and neck and lung cancer (Seiwert, Gajewski, Salgia)
•Recruitment of Remzi Bag, MD, to lead our lung transplant
program
I am very proud of the Department ’s achievements over the
past year, and the remarkable impact our faculty have had
on patient care, research and education in the local and global
community. I thank them for their effort, commitment and
dedication to our mission.
•Developed approaches to health care in our local South Side
neighborhoods that will serve as the model for other urban
Everett E. Vokes, MD
communities (Meltzer)
B
2 0 15 A n n u a l R e p o r t
1
ORGANIZATION 2015
Chairman, Department of Medicine......................................................................................................................................Everett E. Vokes, MD
Executive Committee
Table of
CONTENTS
Chairman’s Message
1
Department Organization
3
Special Awards
4
Medicine by the Numbers 6
Clinical Programs Overview
8
Research Programs Overview
10
Educational Programs Overview
12
Section Reports
Cardiology14
Dermatology16
Emergency Medicine
18
Endocrinology, Diabetes & Metabolism
20
Gastroenterology, Hepatology & Nutrition
22
General Internal Medicine
24
Genetic Medicine
26
Geriatrics & Palliative Medicine
28
Hematology/Oncology30
Hospital Medicine
32
Infectious Diseases & Global Health
34
Nephrology36
Pulmonary/Critical Care Medicine
38
Rheumatology40
2
Select High-Impact Publications
42
Residents and Fellows
44
Sponsored Research Awards
50
Committee Highlights 74
Vice Chair of Appointments and Promotions................................................................................................................Dorothy Hanck, PhD
Vice Chair of Education...................................................................................................................................................................John McConville, MD
Vice Chair of Faculty Development.......................................................................................................................................Deborah Burnet, MD
Vice Chair of Research....................................................................................................................................................................Julian Solway, MD Vice Chair of Research (Basic)...................................................................................................................................................Bana Jabri, MD, PhD
Vice Chair of Research (Translational)................................................................................................................................Ravi Salgia, MD, PhD
Associate Vice Chair – Inpatient Operations.................................................................................................................Savitri Fedson, MD
Associate Vice Chair – Ambulatory Operations..........................................................................................................Lisa Vinci, MD
Associate Vice Chair – Quality..................................................................................................................................................Andrew Davis, MD
Associate Vice Chair – Urban Health Initiative/EMR & Transplant..................................................................Edward Garrity, MD
Executive Administrator................................................................................................................................................................Kenneth C. Goodell
Associate Executive Administrator.......................................................................................................................................James Manthey
Section Chief Council
Cardiology................................................................................................................................................................................................James Liao, MD
Dermatology...........................................................................................................................................................................................Christopher Shea, MD
Emergency Medicine........................................................................................................................................................................Linda Druelinger, MD
Endocrinology, Diabetes & Metabolism.............................................................................................................................Ronald Cohen, MD
Gastroenterology, Hepatology & Nutrition....................................................................................................................David Rubin, MD
General Internal Medicine...........................................................................................................................................................Deborah Burnet, MD
Genetic Medicine................................................................................................................................................................................Dan Nicolae, PhD (interim)
Geriatric & Palliative Medicine..................................................................................................................................................William Dale, MD, PhD
Hematology/Oncology...................................................................................................................................................................Walter Stadler, MD
Hospital Medicine................................................................................................................................................................................David Meltzer, MD, PhD
Infectious Diseases & Global Health.....................................................................................................................................David Pitrak, MD
Nephrology..............................................................................................................................................................................................Arlene Chapman, MD
Pulmonary/Critical Care Medicine.........................................................................................................................................Gökhan Mutlu, MD
Rheumatology.......................................................................................................................................................................................Marcus Clark, MD
Committee Chairs
Diversity Committee.........................................................................................................................................................................Monica Vela, MD
Women’s Committee........................................................................................................................................................................Helen Te, MD
Chief Residents
2016 Chief Residents.........................................................................................................................................................................Justin Boike, MD
Maureen Lyons, MD
Patrick Lyons, MD
Michelle Martinchek, MD
Senior Management
Clinical Revenue and Billing........................................................................................................................................................Lisa Kogan
Clinical Research Support............................................................................................................................................................Allison Buonamici
Budget and Finance...........................................................................................................................................................................Sunila Goel
Academic Human Resources......................................................................................................................................................Sharon Frazier
Staff Human Resources..................................................................................................................................................................Chris Yaros
Information Systems.........................................................................................................................................................................Max Marchevsky
Research Administration...............................................................................................................................................................Katie Pizer
Clinical Trials Financial Group...................................................................................................................................................Ashley Hoambrecker
3
Special
AWARDS 2015
Elec ted Fellows of the American Academy of Ar ts
and Sciences
Elected Members of the Institute
of Medicine/National Academy of Medicine
Graeme Bell, PhD
Olufunmilayo Olopade, MD
Graeme Bell, PhD
Robert Gibbons, PhD
David Meltzer, MD, PhD++
Kenneth Polonsky, MD
Elected Members of the A ssociation of
American Physicians
Michael A. Becker, MD
Eugene Chang, MD
Marcus Clark, MD
Fredric Coe, MD
Alan Leff, MD
Bana Jabri, MD, PhD
James Liao, MD
David Meltzer, MD, PhD+
Yusuke Nakamura, MD, PhD
Mark J. Ratain, MD
Samuel Refetoff, MD
Angelo Scanu, MD
Mark Siegler, MD
Julian Solway, MD
F. Gary Toback, MD, PhD
Everett Vokes, MD
Elected Members of the American Society for
Clinical Investigation
Marisa Alegre, MD, PhD
Michael A. Becker, MD
Eugene Chang, MD
Marcus Clark, MD
Fredric Coe, MD
Suzanne Conzen, MD
Elbert Huang, MD, MPH
Thomas Gajewski, MD, PhD
Lucy Godley, MD, PhD
Harvey Golomb, MD
James Liao, MD
Alan Leff, MD
David Meltzer, MD, PhD
Gokhan Mutlu, MD
Samuel Refetoff, MD
Angelo Scanu, MD
Julian Solway, MD
Everett Vokes, MD
4
American College of Physicians Masters
Holly Humphrey, MD
Mark Siegler, MD+
Depar tment of Medicine Named Professorships
• Graeme Bell, PhD—Louis Block Distinguished Service Professor
• Eugene Chang, MD—Martin Boyer Professor
• Marshall Chin, MD—Richard Parillo Family Professor in Healthcare Ethics
• Harvey Golomb, MD—Lowell T. Coggeshall Professor
• Holly Humphrey, MD—Ralph W. Gerard Professor
• James Liao, MD —Harold H. Hines, Jr. Professor
• Michelle Le Beau, PhD—Arthur and Marian Edelstein Professor
• Olufunmilayo Olopade, MD—Walter L. Palmer Distinguished Service Professor
• Nanduri Prabhakar, PhD—Harold H. Hines, Jr. Professor
• Kenneth Polonsky, MD—Richard T. Crane Distinguished
Service Professor
• Mark Ratain, MD—Leon O. Jacobson Professor
• Samuel Refetoff, MD—Frederick H. Rawson Professor
• Christopher Rhodes, PhD—Kovler Family Professor
• David Rubin, MD—The Joseph B. Kirsner Professor of Medicine
• Christopher Shea, MD—Eugene J. Van Scott Professor
in Dermatology
• Mark Siegler, MD—Lindy Bergman Distinguished
Service Professor
• Julian Solway, MD—Walter L. Palmer Distinguished
Service Professor
• Walter Stadler, MD—Fred C. Buffett Professor
• Wendy Stock, MD—Anjuli Seth Nayak Professor in Leukemia++
• Daniel Sulmasy, MD, PhD—Kilbride-Clinton Professor
• Eve Van Cauter, PhD—Frederick H. Rawson Professor
• Everett Vokes, MD—John E. Ultmann Professor
• Irving Waxman, MD—Sara and Harold Lincoln
Thompson Professor
+New in FY 15
++New in FY 16
Mark Siegler, MD (center) as the 2014 Distinguished Service Award Recipient
Distinguished Ser vice Awards
L e i f B . S o r e n s e n , M D , P h D Fa c u l t y R e s e a r c h A w a r d
• Joseph B. Kirsner, MD, PhD (2006)
• Janet Rowley, MD (2007)
• Louis Cohen, MD (2008)
• Morton Arnsdorf, MD (2009)
• Angelo Scanu, MD (2010)
• Keyoumars Soltani, MD (2011)
• Jesse B. Hall, MD (2013)
• Roy E. Weiss, MD, PhD (2014)
• Mark Siegler, MD (2014)
• Samuel Refetoff, MD (2015)
• Suzanne Conzen, MD (2007)
• Marisa Alegre, MD, PhD (2008)
• Anne Sperling, MD (2008)
• Bana Jabri, MD, PhD (2009)
• Eric Svensson, MD, PhD (2010)
• Elbert Huang, MD (2011)
• Patrick Wilson, PhD (2012)
• Konstantin Birukov, MD, PhD (2013)
• Lucy Godley, MD, PhD (2013)
• John Schneider, MD, MPH (2014)
• Yu Ying He, PhD (2015)
Ar thur H. Rubenstein, MD Mentorship Award
• Eugene B. Chang, MD (2007)
• Julian Solway, MD (2008)
• Jesse Hall, MD (2009)
• Roberto Lang, MD (2010)
• Marshall Chin, MD (2010)
• Frederic Coe, MD (2011)
• Olufunmilayo Olopade, MD (2012)
• Deborah Burnet, MD (2013)
• Mary Strek, MD (2014)
• David Meltzer, MD, PhD (2015)
Diversit y Award
• Monica Vela, MD (2010)
• David Howes, MD (2011)
• Blanca Camoretti-Mercado, PhD (2012)
• Minoli Perera, PhD (2013)
• Monica Peek, MD, MPH (2014)
• John Schneider, MD, MPH (2015)
Biological Science Division Awards
Distinguished Faculty Award for Leadership & Good Citizenship
• Michelle Le Beau, PhD
Distinguished Clinician (Junior) Award
• Blase Polite, MD
Distinguished Educator/Mentor (Junior) Award
• Keme Carter, MD
5
BY THE NUMBERS
Sp on s ore d Aw ar d s by Fun din g S ource
(t o t a l c o s t s i n m i l l i o n s)
14
Subspecialty Sections
$140.0
286 Clinical and Research Faculty
$120.0
Millions
20 in NIH Funding
#
3 in NIH Funding/Faculty
97 M Total NIH Awards
$
134 M Total Sponsored Research Awards & Clinical Trials Earnings
State/Assoc/Found.
Industry
14,000
12,893
12,000
10,890
10,000
15,961
GI Non-Interventional GI Interventional Bronchoscopies 9,946
4,074
1,941
Cardiac Procedures Echo Studies Cardiac Catheterizations Nuclear Studies Interventions EP Studies and Ablations Cardiac Device Invasive
Procedures 18,305
Admissions
13,896
1,969
1,008
640
287
8,000
8,638
11,526
9,807
6,000
4,000
2,000
FY 11
FY 12
505
FY 13
FY 14
FY 15
O utp atien t V i sit s *
285,000
280,000
Trainees 312
Subspecialty Fellows Residents 181
Cardiology Chief Residents
4
Internal Medicine Residents
99
Physician Scientists
Development Residents 5
Dermatology Residents 10
Emergency Medicine Residents 47
Medicine Pediatric Residents 16
FY 13
Inp a tien t A dmi s sion s
Educ a tional Ac ti v it y
6
FY 12
PHS
188
60
35
30
26
6
FY 15
$20.0
Admissions 12,893
Outpatient Visits
224,758
Emergency Room Encounters
55,907
RVUs 1,052,079
Bone Marrow Transplants
Kidney Transplants
Heart Transplants
Liver Transplants
Lung Transplants
Kidney/Pancreas Transplants
FY 14
$60.0
C linic al Ac ti v it y
GI Procedures $135.8
$121.0
$40.0
$
345
$139.0
$80.0
FY 11
Transplant Cases $129.6
$100.0
Re s e arc h Ac ti v it y
#
$124.5
131
Dermatology 26
Hospitalist Scholars 1
Infectious Diseases &
Global Health Nephrology Adult & Pediatric Endocrinology,
Diabetes & Metabolism 12
280,665
275,000
12
6
9
Gastroenterology, Hepatology
& Nutrition 18
Pulmonary & Critical Care 13
Rheumatology 4
General Internal Medicine 2
Sleep Medicine 4
Geriatrics & Palliative Medicine 3
Hematology/Oncology 21
Visits
270,000
265,000
265,284
260,000
255,000
250,000
267,805
260,015
253,255
245,000
240,000
FY 11
FY 12
FY 13
FY 14
FY 15
*includes onsite, offsite and emergency room and excludes student care center
7
Overview
CLINICAL PROGRAMS
a 5% decrease in length of stay in the ED for admitted patients.
This improvement, coupled with the recent increases in inpatient
bed capacity, continues to maximize efficiency and enhance bed
utilization and safety. In FY 15, the ED implemented the “rapid
assessment unit” concept in triage, thereby decreasing time
by 30-60 minutes overall for discharged patients and is in the
process of defining a new procedure for adult ED admissions and
hold orders.
Qualit y and Efficienc y Initiatives
The Department of Medicine is comprised of eminent clinical innovators who continue to be
recognized for their high level of expertise. The Department’s clinical programs continue to
demonstrate excellence across the broad spectrum of subspecialty patient care services for the
treatment of our highly complex and diverse patient population. Institutionally, the
Department is recognized for its impactful patient care and volumes across all domains. In
FY 15, clinical faculty generated over one million physician work RVUs (wRVUs), a performance
representing a significant portion of the clinical practice activity of the entire University of
Chicago Medicine (UCM) and representing a 7% increase over last fiscal year.
K e y h i g h l i g h t s f r o m F Y 15 i n c l u d e :
• Increased admissions, outpatient subspecialty and offsite clinic visits
• Significant growth in the advanced heart failure program
• Growth in transplant programs
• Notable improvement in emergency department efficiency
• Significant recognition for quality and safety
• Establishment of the Heart and Vascular Center
Vo l u m e G r o w t h
In FY 15, the Department realized significant volume increases
in admissions, subspecialty outpatient visits and procedures.
On the inpatient side, the Department witnessed a 12% increase
in admissions. Contributing to this increase were the successful
efforts by the Clinical Operations Committee (CLOC). Led by
Stephen Weber, MD, and John McConville, MD, the CLOC Inpatient
Subcommittee developed a new coverage plan, created a new
supportive care unit and refined the inpatient coverage systems
for MICU patients in both Mitchell Hospital and the Center for
Care & Discovery (CCD). With the recruitment of Nir Uriel, MD, in
FY 14, the heart failure program grew significantly in FY 15. With
the addition of four heart failure experts over the past two years,
activity doubled as compared to last year.
In addition to the increase in patient admissions, the Department
attained a 3% increase in on-site outpatient subspecialty practice
visits for a total of 141,000, while primary care visits increased
8
by 4% with over 55,000 visits. The offsite subspecialty practice
at 150 E. Huron continued to thrive with a 16% increase in visits.
Procedure volume increased by nearly 7%, with GI procedures
remaining steady at approximately 16,000 and cardiac procedures
increasing by more than 11%. Under the direction of Michael
Bishop, MD, the bone marrow transplant program realized a 10%
increase from the prior year and successfully conducted the
first outpatient bone marrow transplant. Within the solid organ
transplant program, volumes increased by 15%.
Emergency Medicine Metrics
Improving clinical operations in the emergency department (ED)
has been a primary focus for the past three years. With support
from both UCM and the Department, the Emergency Medicine
Operations Committee has achieved important outcomes in
FY 15, including a continued reduction in diversion hours, a 22%
decrease in number of patients who left without being seen and
In FY 15, the University of Chicago Medicine was named one of
the safest hospitals in the country for the seventh consecutive
year by the prestigious and independent Leapfrog Group. In
Leapfrog’s semi-annual Hospital Safety Score, UCM garnered
a “Straight As” designation for its consistency in delivering
the highest level of quality and protecting its patients from
preventable medical errors, injuries and infections while in the
hospital. Since the survey began in June 2012, UCM is one of only
182 U.S. hospitals, out of about 5,000, to receive an A rating in all
seven survey periods, placing UCM in a truly elite category of
continual, sustained top-tier performance in patient safety.
Through the efforts of Michael Howell, MD, associate chief
medical officer for clinical quality, UCM was recognized as the
safest medical center in Chicago, scoring in the top 10% in the
country in Medicare’s Patient Safety Index and better than the
vast majority of academic medical centers in the country. Also in
FY 15, the Centers for Disease Control and Prevention designated
UCM as a national Ebola Treatment Facility based on our ability
to care for patients while minimizing risk to healthcare workers.
Under the leadership of Emily Landon, MD, the UCM’s Ebola
Treatment Center was established, representing only one of 39
such centers in the United States and one of three in Chicago.
Under the direction of Andrew
Davis, MD, associate vice chair
for quality, the Department
implemented several quality
initiatives, including judicious
blood transfusion policies
that resulted in a reduction
of packed RBC use by 15%, and
piloted a 48-hour post-discharge
phone call program to assure
adequate discharge planning and
reduce readmission risk. Also
new in FY 15, Medicine faculty
developed a sepsis bundle
Dr. Andrew Davis
program that resulted in a 30%
reduction in sepsis-related mortality on the medicine inpatient
service, and the Department’s offsite dialysis units received a
four-star rating from the Dialysis Facility Compare Star Ratings,
Center for Medicaid and Medicare Services Program. Finally,
within the oncology outpatient practice, Chadi Nabhan, MD
(medical director), led efforts that resulted in the oncology
clinic successfully obtaining three-year certification status by
the American Society of Clinical Oncology’s Quality Oncology
Practice Initiative.
Hear t and Vascular Center
In FY 15, UCM launched the Heart and Vascular Center, combining
the expertise of Medicine, Pediatrics and Surgery to meet the
growing needs of patients seeking cardiovascular care in a highly
coordinated setting. Under the medical direction of James
Liao, MD, the new center incorporates more than 40 specialists,
as well as dedicated nursing and support staff and advanced
technologies into a carefully orchestrated network of worldrenowned experts focused on medical problems involving the
heart and blood vessels.
Offsite Collaborations
The Department’s key collaborative sites at Silver Cross and
ACCESS Community Heath and Community Health – Englewood
continue to be positive across all three missions, with clinical
care at the forefront of each of these relationships.
The University of Chicago Medicine Comprehensive Cancer
Center at Silver Cross Hospital marked its fourth anniversary in
June. Over the past year, the program in New Lenox has been
able to grow remarkably and has enhanced care for patients
throughout the region. Visits to the Center’s medical oncology
services are up 20% percent over last year.
As part of the Urban Health Initiative clinical efforts, the
Department continued with its subspecialty presence in the
community at a Federally Qualified Health Center–ACCESS
Grand Boulevard Health Center. Additionally, the Department’s
presence at Community Health continues to be quite successful,
with residents providing patient care at this free clinic in Englewood.
In FY 16, the Department of Medicine looks forward to working
with UCM leadership to finalize plans for the opening of the new
Center for Advanced Care in Orland Park and the expansion of
inpatient floors in the Center for Care and Discovery, as well as
creating a clinical presence in Chicago’s South Loop.
GI Cancer Risk Clinic Physicians
9
Overview
RESEARCH PROGRAMS
The inaugural Janet D. Rowley Research Day was held on March 3,
2015. The day kicked off with a touching tribute to Dr. Janet
Rowley, followed by an outstanding talk on the role of cancer
genetics in breast and ovarian cancer by Judy Garber, MD,
Professor of Medicine at Harvard Medical School and Director,
Center for Cancer Genetics and Prevention at the Dana Farber
Cancer Institute. Following that, over 100 faculty and fellows
participated in the poster event with all subspecialties
represented. Catherine Bonham, MD, was awarded the People’s
Choice and Best Clinical Research Abstract (Fellow) Awards for
her presentation entitled “Prostacyclin and Oral Vasodilator
Therapy In Sarcoidosis Associated Pulmonary Hypertension.”
Other Best Abstract Award winners included: Drs. Cevher Ozcan,
Kichul Ko, Erin Hanlon and Neda Laiteerapong in the faculty
category, and Drs. Emily Curran, Houda Alachkar and Robert Daly
in the fellow/trainee category. Also in FY 15, the Department held
its second Clinical and Translational Research Forum focused on
precision medicine. The all-day event featured talks from experts
in the field and K awardees that focused on metabolic diseases,
cancer medicine and health disparities.
8 Conte Center for Computational Systems Genomics of
Neuropsychiatric Phenotypes (P50)—Andrey Rzhetsky, PhD
Recognizing the research success of an outstanding mid-level
scientist, the Department named Yu Ying He, PhD (Dermatology),
as the recipient of the 2015 Leif B. Sorensen, MD, PhD, Faculty
Research Award for her impactful work in skin cancer.
6 Computational Modeling of Tumor Burden by CT to Advance
Cancer Therapeutics (R01)—Michael Maitland, MD, PhD*
The Department of Medicine has a long tradition of conducting original and rigorous
biomedical research of fundamental significance. With expertise from our impressive pool
of scientists, the Department is changing medicine with impactful breakthroughs that are
generating important knowledge and accelerating the application of research innovations
into treatment options for patients at an individualized level. The Department is the largest
recipient of funding for research and training in the Biological Sciences Division, with
hundreds of awards from the National Institutes of Health, private foundations and industry
to support basic, clinical and translational research projects.
Recognition of our outstanding research programs is indicated
by a consistent ranking in the top 20 academic departments
in NIH funding. In 2014, the Department ranked as #20 for NIH
funding among 125 academic departments of medicine and #3
in NIH funding per faculty member by U.S.News & World Report.
Within the Division of Biological Sciences, Medicine accounts for
over a third of all the research dollars awarded, with nearly $116 M
in total cost sponsored awards. Federal awards accounted for
nearly $95 M and include 77 R series, 24 K series, 11 training and 9 P
series grants. Non-federal, association, state and foundation
awards totaled $14.3 M in FY 15. The Department conducted more
Research Vice Chairs: Dr. Ravi Salgia, Dr. Bana Jabri, Dr. Julian Solway
10
than 1,700 clinical research studies, including approximately
500 industry-funded studies that accounted for $18.7 M in total
cost earnings. Our goal to train the next generation of academic
physician scientists successfully yielded four new career
development (K) awards during the past year and a K12 to establish
a patient-centered outcome research training program (David
Meltzer, MD, PhD—program director).
In FY 15, the Department of Medicine successfully secured over
50 new or competitively renewed federal awards. Most noteworthy
were two new UH2 grants awarded to Julian Solway, MD, and
Nanduri Prabhakar, PhD, to support the pre-clinical development
of myosolvins for asthma, and therapeutic targeting of carotid
body chemoreflex for sleep disordered breathing, respectively,
and a new U01 awarded to Louis Philipson, MD, PhD, to establish a
Chicagoland Diabetes TrialNet Clinical Center. Additionally, over
20 faculty were the recipients of new federal R series awards.
The Department was the recipient of several new significant
foundation awards including the Prostate Cancer Foundation
(Suzanne Conzen, MD—PI) and Falk Medical Research Foundation
(Olufunmilayo Olopade, MD—PI).
9 Alterations of Circadian Timing in Sleep and Aging (P01)—
Eve Van Cauter, PhD
Selec t High Impac t Awards:
1 Enhancement of Beta Cell Function with Pharmacologic and
Sleep Apnea Treatment (U01)—David Ehrmann, MD & Eve Van
Cauter, PhD
2 A New Statistical Paradigm for Measuring Psychopathology
Dimensions in Youth (R01)—Robert Gibbons, PhD
3 Open Science Data Cloud PIRE; Training & Workshops in
Data Intensive Computing Using the Open Science Data Cloud
(National Science Foundation)–Robert Grossman, PhD
4 The Open Genomic Data Commons (OGDC)—
Robert Grossman, PhD
5 Viral Infections and Celiac Disease Pathogenesis (R01)—
Bana Jabri, MD, PhD*
7 Integrated Inpatient/Outpatient Care for Patients at High Risk
of Hospitalization (AHRQ)—David Meltzer, MD, PhD
8 Development of New Targeted Cancer Therapies
(OncoTherapy Science)—Yusuke Nakamura, MD, PhD
9 Using Genomics to Reduce Breast Cancer Disparities in the
African Diaspora (U01)—Olufunmilayo Olopade, MD
10University of Chicago Program for Expanded Human
Immunodeficiency Testing for Disproportionately Affected
Populations in Healthcare Settings in Chicago (CDPH)—
David Pitrak, MD
11 Therapeutic Targeting of Carotid Body Chemoreflex for Sleep
Disordered Breathing (UH2)—Nanduri Prabhakar, PhD*
12 Pharmacogenetics of Anticancer Agents Research (U10)—
Mark Ratain, MD & Eileen Dolan, PhD
2015 Research Day Committee Members with Dr. Judy Garber
Depar tment of Medicine Progr ammatic Awards
1 Diabetes Research Training Center (P60)—Graeme Bell, PhD
2 Inflammatory Bowel Disease and Mucosal Inflammation,
Immunology, and Microbiology of the G.I. Tract (P30)—
Eugene Chang, MD
3 Identification of Aberrant Tissue Responses to Intestinal
Microbes that Cause Ulcerative Colitis (Helmsley Trust)—
Eugene Chang, MD
4 Chicago Center for Diabetes Translation Research (P30)—
Marshall Chin, MD & Monica Peek, MD
5 Pathogenesis of Calcium Nephrolithiasis (P01)—
Elaine Worcester, MD
13 The Genetic Basis of Cross-tissue Protein Expression
Variability in Humans (U01)—Barbara Stranger, PhD
14 Big Machine Science (Defense Advanced Research Projects
Agency)—Andrey Rzhetsky, PhD*
15 Re-Engineering Translational Research at the University of
Chicago (U54)—Julian Solway, MD
16 Preclinical Development of Myosolvins, A New Class of
Medicine for Asthma (UH2)—Julian Solway, MD*
17 Functional Genomics of IL-33 Expression and Asthma
Risk (R01) —Anne Sperling, PhD
18 Airway Inflammation and HLA-G in Asthma (U19)—
Steven White, MD
*New in FY 15
6 Chicago South Side Cancer Disparities Initiative(P20)—
Karen Kim, MD
7 Integrative Consequences of Hypoxia (P01)—
Nanduri Prabhakar, PhD
11
Overview
EDUCATIONAL PROGRAMS
The Department of Medicine is deeply committed to the education and training of skilled
physician scientists and leaders bound for careers in academic medicine in an environment
supporting cultural diversity and patient safety. Under the leadership of John McConville,
MD, the Department’s educational programs continue to successfully prepare trainees for
careers in clinical medicine, teaching and biomedical research. Within the internal medicine
residency (IMR) program, many of the graduates pursue sub-specialty
training. The 2014 fellowship match successfully matched 29 graduating
residents into many of the most competitive and premier fellowship
programs in the country, including 12 who continued their training at
the University of Chicago. Cardiology was the most popular fellowship
choice, with ten housestaff matching to outstanding programs
across the country. Other frequent fellowship choices included
gastroenterology (7), hematology/oncology (4), pulmonary/critical
care (4), endocrinology (2) and allergy/immunology (2).
Dr. John McConville
In FY 15, Kate Thompson, MD, again led the internal medicine Intern
Selection Committee. Over 400 candidates were interviewed,
and an exceptional PGY 1 class of 41 interns was successfully
recruited from outstanding medical schools. Demonstrating the
importance of cultural diversity, 15% of the new intern class is
underrepresented minorities. Applicants continue to be attracted
to the rigorous clinical training, diverse patient population and
outstanding faculty mentorship which are the hallmarks of the
IMR. In addition, the ultrasound curriculum and the recent upgrade
to the iPad mini for all housestaff continue to be novel aspects of
our internal medicine training program.
In FY 15, the IMR program continued its efforts to reach out to
alumni via newsletters as well as hosting the first ever reunion. In
September 2014, graduates from the IMR program’s intern classes
of 1980-1986 returned to the Department to reconnect with past
12
a Twitter curriculum, all of which were designed by James Ahn,
MD. Medical education continues to be a strength and a focus in
the residency, as two additional emergency medicine residents
were selected as part of the University of Chicago MERITS/
GME scholars program. Additionally, the Section of Emergency
Medicine has created a medical education fellowship and
graduated its first medical education scholar, Mike Paddock, DO.
Under the direction of Sarah Stein, MD, the dermatology
residency program continues its mission of contributing to the
field of academic dermatology and providing excellent resident
education and training. In FY 15, the Section of Dermatology
hosted the annual Chicago Dermatological Society Educational
Conference that included the Allen Lorincz Memorial Lecture
as well as the Maria Medenica Dermatopathology Lecture.
Both lectures were presented by Wayne Grayson, MBChB,
PhD, FCPath (University of Witwatersrand), who spoke on the
dermatopathology of HIV/AIDS and on cutaneous infections in
non-immunocompromised hosts. The dermatology residency
program received its highest number of applicants in 2014, and
successfully matched outstanding candidates to each of the
three available positions. Additionally, the Section hosted ten
Pritzker medical students and eleven visiting medical students
on the clinical dermatology elective rotation.
H o n o r s : The Department of Medicine’s extraordinary pool of
talented educators continues to be recognized for excellence in
undergraduate and graduate medical education, both institutionally
and nationally. In FY 15, Keme Carter, MD, was recognized with
five separate awards for her outstanding contributions to
medical education, including the Doroghazi Outstanding Clinical
Teaching Award for the second straight year. Jeanne Farnan, MD,
MHPE; Philip Hoffman, MD; and Scott Stern, MD; were recognized
as “Favorite Faculty” by the Pritzker graduating class for the fifth
time in as many years. Vineet Arora, MD, was the recipient of
Pritzker’s John D. Arnold Mentorship Award and the Frederick
L. Brancati Mentorship and Leadership Award by the Society of
General Internal Medicine.
The Department is home to several nationally recognized medical
research training programs, including seven NIH-funded training
(T32) grants in cardiology, adult and pediatric endocrinology,
oncology, respiratory biology, digestive diseases, sleep and the
medical scientist training program. The Department also holds
three NIH K12 grants in oncology, lung disease and outcomes
research, and five F series NIH awards.
Division of Biological Sciences Awards
• Distinguished Educator/Mentor (Junior) Award—Keme Carter, MD
Depar tment of Medicine Awards
• Preclinical Teacher of the Year—Philip Hoffman, MD
• Clinical Teacher of the Year—Scott Stern, MD
• Postgraduate Teaching—Sarah Stein, MD
• Arthur Rubenstein, MD Mentorship Award—
• Medicine Resident Teaching Awards:
Nir Uriel, MD
JP Kress, MD
Anne Hong, MD
Anna Zisman, MD
• Emergency Medicine Resident Awards:
Outstanding Emergency Medicine Faculty Member Clinical Teaching—Keme Carter, MD
Outstanding Emergency Medicine Faculty Member Mentorship—Christine Babcock, MD
• Resident Research Day 2015
Most Outstanding Research Poster—Sara Hock, MD
Housestaff Choice Award—Eric Brandt, MD
Most Outstanding Clinical Vignette—Jeff Jacobs, MD
P r i t z ke r S c h o o l o f M e d i c i n e E d u c a t i o n a n d
Mentorship Awards
• John D. Arnold Mentorship Award—Vineet Arora, MD
• Doroghazi Outstanding Clinical Teaching Award—
Keme Carter, MD
• Leonard Tow Award—Keme Carter, MD
• Gold Humanism Keynote Speaker—Monica Vela, MD
• Faculty Physician Peer Role Model Award—Mindy Schwartz, MD
• LDH Wood Pre- Clinical Teaching Award—Jeanne Farnan, MD
• Resident Humanism and Excellence in Teaching Award—
classmates and colleagues to learn how both the hospital and
residency program have evolved. Special guests for the reunion
weekend included Pierce Gardener, MD, and Arthur Rubenstein,
MD, who served as the IMR program director and chair of the
Department of Medicine, respectively, in the 1980s.
With leadership from Christine Babcock, MD, MSc, the emergency
medicine residency program continues to expand its robust
education platform focusing on a cutting-edge didactic curriculum,
medical education research and simulation opportunities for
instruction on effective teaching for residents. The didactic
curriculum has expanded to include PGY-level specific didactics
with a novel “flipped classroom” approach, Pecha Kucha
style talks, as well as increased multidisciplinary presence at
conferences. Adjunctive curriculums include former residents
as teachers (RAT) curriculum, a senior leadership curriculum and
Internal Medicine Residents: Drs. Juan Reyes Genere,
David Kopelman and Michelle Fletcher
Gray Akoegbe, MD
• Student-Run Free Clinic Faculty Volunteer Award—
Marc Robinson, MD
• Favorite Faculty Awards:
2014 Housestaff Reunion Committee with former chairman,
Dr. Arthur Rubenstein and former IMR director, Dr. Pierce Gardner,
and Dr. Everett Vokes and Dean Kenneth Polonsky, MD.
Adam Cifu, MD
Jason Poston, MD
Keme Carter, MD
Mark Siegler, MD
Jeanne Farnan, MD
Scott Stern, MD
Philip Hoffman, MD
Monica Vela, MD
Holly Humphrey, MD
James Woodruff, MD
2 015 A l p h a O m e g a A l p h a A w a r d s
• Faculty Honorees—Keme Carter, MD, and Savitri Fedson, MD
• Inaugural Leadership Award—Monica Vela, MD 2 0 15 A n n u a l R e p o r t
13
Section of
CARDIOLOGY
Dr. James Liao
In FY 15, the University of Chicago Medicine launched the new Heart and Vascular Center
(HVC), combining expertise from three clinical specialties — medicine, pediatrics and surgery —
to meet the growing needs of patients seeking care for cardiovascular disease. James Liao,
MD, chief of the Section of Cardiology, heads the HVC as medical director. Adding to the
strength of the HVC are faculty from the Section of Cardiology who are nationally known for
their groundbreaking discoveries and clinical expertise in the diagnosis and treatment of
heart disease.
In FY 15, the Section welcomed several new faculty members
to enhance the heart failure, electrophysiology, interventional
and research programs. Sirtaz Adatya, MD, assistant professor
of medicine, specializes in heart transplantation and ventricular
assist devices. Gaurav Upadhyay, MD, assistant professor of
medicine, is an interventional electrophysiologist with academic
interests in the management of complex arrhythmias, innovative
left ventricular lead targeting for cardiac resynchronization
therapy and integrative approaches for device-based population
management in heart failure. John Blair, MD, assistant professor
of medicine, has had extensive training in the use of transradial
catheterization and intervention, a method of catheterization
associated with reduced bleeding and enhanced patient
comfort. He is one of few cardiologists who perform coronary
physiology studies, which aid in diagnosing coronary microvascular
dysfunction in a range of challenging clinical scenarios.
Nitasha Sarswat, MD, specializes in advanced heart failure and
heart transplantation. Adding to the cardiovascular research
program were the recruitments of Cevher Ozcan, MD, assistant
professor of medicine, and Michael Broman, MD, PhD. Dr. Ozcan,
an NIH K awardee, investigates mitochondrial mechanisms
of atrial fibrillation (AF) and the role of cellular energetics
and metabolism in mechanisms of arrhythmias. Dr. Broman is
a physician scientist interested in cardiac development and
cellular electrophysiology.
working closely with the ED for patients who present with ADHF,
an intensive education program about CHF while in-house, and a
strong emphasis on transitions of care/discharge planning with
close outpatient follow-up.
FY 15 also showed an increase in cardiac procedures over last
year. The Cardiac Imaging Center (Roberto Lang, MD—director)
saw steady growth in the number of imaging tests and procedures,
notably 3D echocardiographic guidance of transcatheter
treatment of structural heart diseases and valve replacement,
as well as MRI tests that provide high resolution images of
myocardial perfusion during vasodilator stress. Since 2012,
over 60 patients have been successfully treated with TAVR,
with 45 TAVRs in 2015. The interventional cardiology program
Dr. Sirtaz Adatya
Dr. John Blair
Dr. Nitasha Sarswat
The Section’s clinical programs showed significant growth in FY 15,
most notably in the heart failure (HF) program. Under the direction
of Nir Uriel, MD, the HF program flourished in FY 15, substantially
increasing volume growth and nearly doubling wRVUs as compared
to one year ago. Adding to the HF success was the creation of a
new program to reduce readmission rates for patients admitted
with acute decompensated heart failure. The program focuses on
In the educational realm, the Section is home to one of the
oldest National Institutes of Health-funded cardiovascular
research programs in the nation, as well as four ACGMEaccredited fellowship training programs. Under the leadership
of Dr. Liao, the Section’s T32 program was successfully renewed
for years 36-40. The seventh annual Morton F. Arnsdorf
Cardiovascular Sciences Research Day, chaired by Marion
Hofmann-Bowman, MD, PhD, and Francis Alenghat, MD, PhD,
featured nearly 60 presentations by faculty and trainees in
cardiology, cardiovascular surgery and emergency medicine.
The Section’s research portfolio included the acquisition of
several new grants, including funds from the American Heart
Association and the American Society for Echocardiography
awarded to Dr. John Blair and Victor Mor-Avi, PhD, for their clinical
research programs in heart failure and imaging, respectively.
Finally, the Section mourned the loss of two distinguished faculty
members in FY 15: Rory Childers, MD, an expert in computerized
electrocardiography, and Harry Fozzard, MD, a pioneer in the
study of cardiac muscle activity whose research helped lay the
foundation for modern clinical electrophysiology.
Highligh t s , Di s cover ie s an d Accomp li shm en t s
• Roberto Lang, MD—Recipient of the Meritorious Service Award
from the American Society of Echocardiography
• Mardi Gomberg-Maitland, MD, PhD—Named chairman of the Data
and Safety Monitoring Committee for the NIH Multicenter Vascular
Interventions, Innovations and Therapeutic Advances Trial
• Nir Uriel, MD—Named vice-chair and incoming chair for the
Scientific Council on Mechanical Circulatory Support of the
International Society for Heart and Lung Transplantation, and
recipient of the Department of Medicine’s Medical Resident
Teaching Award
Dr. Cevher Ozcan
Dr. Michael Broman
high risk of sudden death; they are also associated with
relatively low rates of lead failure or complications that require
repeated operations (Burke, et al., Journal of the American
College of Cardiology, 2015)
• Found that ROCK inhibition has great potential to be a powerful
therapeutic tool in the treatment of idiopathic pulmonary
fibrosis (Liao, et al., Pharmacology Review, 2015)
• Found that the mitochondrial superoxide dismutase mimetic,
MnTABP, can prevent endothelial cell progenitor senescence and
enhance angiogenesis (Liao, et al., Vascular Pharmacology, 2015)
• Martin Burke, DO—Elected to the editorial board of Heart • Identified S100/RAGE as an accelerating factor for the
• Determined that subcutaneous implantable cardioverter-
• Demonstrated significantly reduced heart failure hospitalization
• Tamar Polonsky, MD—Recipient of the Department of Medicine’s Outstanding Clinical Service Award
During the past year, Section of Cardiology investigators:
Rhythm and to the board of directors of the International Society of Computerized Electrocardiology
defibrillators (S-ICDs) without transvenous high-voltage
electrodes are effective in detecting and terminating
ventricular arrhythmias and avoiding mortality in patients at
development of cardiac hypertrophy and diastolic dysfunction
in chronic kidney disease, suggesting that enhanced fibroblast
growth factor 23 (FGF23) secretion in cardiac fibrous tissue
may promote processes leading to cardiac hypertrophy and
diastolic dysfunction (Hofmann-Bowman, et al., Arteriosclerosis,
Thrombosis and Vascular Biology, 2014)
and enhanced survival in patients with mitral regurgitation
reduction after cardiac resynchronization therapy (Upadhyay, et
al., Heart Rhythm, 2015)
Professors
A ssociate Professors
Assistant Professors
Clinical A ssociates
James Liao, MD
(chief)
Jeanne DeCara, MD
Sirtaz Adatya, MD
Karima Addetia, MD
Jafar Al-Sadir, MD
Savitri Fedson, MD
Francis Alenghat, MD, PhD
Marlon Everett, MD
Martin Burke, DO
Mardi Gomberg-Maitland, MD,
MSc
John Ancsin, PhD*
Nitasha Sarswat, MD
Louis Cohen, MD
(emeritus)
Marion Hofmann-Bowman, MD,
PhD
John Blair, MD
Gene Kim, MD
P a r t-T i m e Fa c u l t y
Dorothy Hanck, PhD
Sandeep Nathan, MD, MSc
Roberto Lang, MD
Amit Patel, MD
Victor Mor-Avi, PhD*
Atman Shah, MD
Matthew Sorrentino, MD
Nir Uriel, MD
Kirk Spencer, MD
Dr. Gaurav Upadhyay
14
(Sandeep Nathan, MD, and Atman Shah, MD—co-directors) also
experienced growth in coronary angiography and coronary
interventions. Along with the advanced heart failure team, the
intervention team formed the “shock service” and initiated
percutaneous extracorporeal membrane oxygenation in
critically ill patients with decompensated heart failure. The
electrophysiology program (EP) (Hemal Nayak, MD—interim
director) published important clinical trials showing the safety
and efficacy of subcutaneous ICD, and implanted the first
leadless pacemaker in Chicago.
Parker Ward, MD
(director, fellowship program)
Rupa Mehta Sanghani, MD
Joshua Moss, MD
Hemal Nayak, MD
Michael Davidson, MD
Coggeshall Instructor
Michael Broman, MD, PhD
Cevher Ozcan, MD
Section Administrator
Jonathan Paul, MD
James Gurchek
Tamar Polonsky, MD, MSCI
Gabriel Sayer, MD
*Research Associate track faculty
Gaurav Upadhyay, MD
Rongxue Wu, PhD*
15
dermatology residency program, under the direction of Sarah
Stein, MD, continues to recruit and train outstanding young
dermatologists. In recognition of her excellent leadership,
Dr. Stein was honored with the Department of Medicine’s
2015 Postgraduate Education Teacher of the Year Award. The
dermatopathology fellowship program (Vesna Petronic-Rosic,
MD—director) provides a peerless training experience to an elite
group of dermatologists and pathologists.
Section of
DERMATOLOGY
Dr. Christopher R. Shea
Dr. Wayne Grayson and dermatology residents at the inaugural
combined Dr. Allan L. Lorincz Memorial and Dr. Maria Medenica
dermatopathology lectures.
Highlights, Discoveries and Accomplishments
• Keyoumars Soltani, MD—Elected to the BSD Faculty Advisory Committee (clinical and translational science)
As one of the top programs in the nation focused on understanding, diagnosing and treating
the skin and its diseases, the Section of Dermatology has a highly dedicated faculty that is
committed to providing outstanding patient care, creating innovative research and training
the future leaders in the field. Under the direction of Christopher R. Shea, MD, the Section
continues to advance across all its missions.
• Vesna Petronic-Rosic, MD, MSc—Received the University of
Chicago Medicine and Biological Sciences Outstanding Service Award, and chaired the Histology Symposium for the World Congress on Cancers of the Skin
• Diana Bolotin, MD, PhD—Served as co-chair of the resident/
fellow abstract session for the American Society for Laser Medicine and Surgery annual meeting
• Yu-Ying He, PhD—Served as co-chair for the Skin Carcinogenesis
In FY 15, Farah Abdulla, MD,
joined the Section as assistant
professor of medicine.
Her research focuses on
developing new protocols and
treatments for patients with
cutaneous lymphomas such
as mycosis fungoides. Prior
to her appointment to the
Section of Dermatology, Dr.
Abdulla served as a Science &
Technology Policy Fellow at
the American Association for
the Advancement of Science
Dr. Farah Abdulla
(AAAS), with placement at the
Department of Defense. She was recently featured on the AAAS
website as a highly successful example of a translational scientist
trained in this prestigious program.
In the clinical realm, the Section continues to be highly productive
in outpatient visits and procedures, and has enjoyed significant
downstream growth in dermatopathology cases. Notably,
procedural productivity grew by 9% in the past year. The Section
is actively engaged in community outreach to grow the volume of
clinical consultations and dermatopathology accessions.
The Section of Dermatology’s investigative programs have
continued to make key contributions to basic research in skin
carcinogenesis and melanocyte differentiation. The significant
impact of the Section’s research is evidenced by its high
national ranking (#24) regarding NIH funding, as compared with
peer Departments of Dermatology. In FY 15, Yu-Ying He, PhD,
16
2015 Leif B. Sorensen, MD, PhD
Faculty Research Award Winner
Dr. Yu-Ying He with Dr. Everett Vokes
successfully secured a new
NIH R01 grant to study the
mechanism of regulation of
global genomic nucleotide
excision repair (GG-NER) by
autophagy, to elucidate its
impact on UVB-induced skin
tumorigenesis and tumor
progression, and to develop
effective GG-NER modulators
for cancer prevention and
therapy. In recognition of
her outstanding research
contributions, Dr. He was
chosen as the 2015 recipient of
the Department of Medicine’s
Leif B. Sorensen, MD, PhD
Faculty Research Award.
Deborah Lang, PhD, has
published novel studies
that advanced the understanding of molecular processes that
regulate melanocyte differentiation and the maintenance of
the stem-cell state. Dr. Lang is also examining how melanoma
cells grow and metastasize through recycling and subverting
the molecular pathways that regulate normal melanocytes
and melanocyte stem cells, and was recently awarded a new
NIH R01 for FY 16.
The Section’s successful educational innovations have further
enhanced its national reputation as a leader in training the next
generation of dermatologists and dermatopathologists. The
Symposium at the American Society for Photobiology’s
biennial meeting
• Aisha Sethi, MD—Named as a fellow within the Emerging
Leaders Program of the Chicago Council on Global Affairs
• Sarah L. Stein, MD—Served as director for the American
• Identified the new critical role of p62 in promoting cell
proliferation and migration in vitro and tumor growth
and metastasis in vivo through its molecular interaction with the oncogenic transcription factor Twist1, and further
characterized the molecular mechanism (He, et al.,
Proceedings of the National Academy of Sciences of the United
States of America, 2014)
• Using skin-specific genetically deficient mice, demonstrated
that SIRT6 functions as an oncogene in the skin epidermis,
indicating that the role of SIRT6 in cancer is dependent on
the molecular context of individual organs (He, et al., Cancer
Research, 2014)
• Using new mouse models, identified SIRT1 as a haploinsufficient
tumor suppressor in the mouse epidermis. This work also
provided in vivo evidence to reconcile the existing debate on
the precise role of SIRT1 in cancer (He, et al., Oncogene, 2015)
Academy of Dermatology’s 2014 Summer Meeting Forum
• Christopher R. Shea, MD—Named as a Top Doctor in Cancer
by Newsweek magazine
During the past year, Section of Dermatology investigators:
• Discovered a novel molecular pathway that drives the
HGF-MET pathway via a feed-forward mechanism that facilitates
melanoma progression, suggesting that components of this
pathway are candidates for factor-directed therapeutics
(Lang, et al., Oncogene, 2014)
• Demonstrated a critical role for SIRT1 in maintenance of the
epidermal barrier, and thereby opened up new opportunities
to develop targeted, mechanism-based strategies to prevent
and treat atopic dermatitis (He, et al., Journal of Allergy and
Clinical Immunology, 2015)
2015 Postgraduate Education Teacher of the Year Award Winner
Dr. Sarah Stein with Dr. Everett Vokes
Professors
Christopher R. Shea, MD
(chief, Eugene J. Van Scott
Professor in Dermatology)
Vesna Petronic-Rosic, MD, MSc
(dermatopathology fellowship
program director)
Farah Abdulla, MD
Keyoumars Soltani, MD
Aisha Sethi, MD
Sarah L. Stein, MD
(dermatology residency
program director)
Diana Bolotin, MD, PhD
Yu-Ying He, PhD
Deborah Lang, PhD
Arlene Ruiz de Luzuriaga, MD
Juliana Basko-Plluska, MD
Sheryl Hoyer, MD
Vivek Iyengar, MD
Nishq Mody
17
In research, the Section was awarded over $4 M in extramural
research funding. New grants in FY 15 include a high impact UH2
federal grant awarded to Nanduri Prabhakar, PhD, to support
therapeutic targeting of carotid body chemoreflex for sleep
disordered breathing, and two grants awarded to Aasim Padela,
MD, from the American Cancer Society and the John Templeton
Foundation to develop mammography intervention for American
Muslims and to explore the intersection of Islam and medical
science, respectively.
Section of
EMERGENCY
MEDICINE
Dr. Linda Druelinger
Under the direction of Linda Druelinger, MD, the Section of Emergency Medicine continues to
maintain its stature as a nationally prominent emergency medicine program. Over the past
year, the emergency department continued to see an increase in volume and improvement in
the operational metrics, including a reduction of hours on diversion, a decrease in number of
patients left without being seen and a decrease in length of stay for discharged patients. In
FY 15, the Section implemented the “rapid assessment unit” pilot with an attending in triage.
This model has shown success in decreasing time to provider and decreasing total time in the
ED by 30-60 minutes overall for all patients.
As one of the oldest training programs in the country, the
emergency medicine residency program (Christine Babcock,
MD—director) continues to attract trainees from outstanding
medical schools, many of whom are successful securing
sought after fellowship positions after completing residency
training. New in FY 15 was the development of an ultrasound
education curriculum by Dr. Helland. In global initiatives, Keegan
Checkett, MD, was named residency program director for the
first emergency medicine training program at the Hospital
Universitaire de Mirebalais in Haiti. Significant contributions to
• Nanduri Prabhakar, PhD—Elected as a foreign fellow, National
During the past year, Section of Emergency Medicine investigators:
• James Ahn, MD—Recipient of the Council of Emergency
Academy of Sciences (India)
Medicine Residency Directors Faculty Teaching Award, 2015
Outstanding Mentorship Award
• Keme Carter, MD—Recipient of the 2015 Biological Sciences
Dr. Gregg Helland
Board for the African Federation for Emergency Medicine
• Katie Tataris, MD—Recipient of the National Association of
EMS Physicians Fellowship Recognition Award
Dr. Thomas Speigel
Dr. Katie Tataris
• Determined that inhibition of the mitochondrial fission protein
dynamin-related protein 1 improves survival in a murine
cardiac arrest model suggesting pharmacological targeting of
mitochondrial fission may be a promising therapy for cardiac
arrest (Sharp, Beiser, et al., Critical Care Medicine, 2015)
• In research relating to the carotid body response to hypoxia,
investigators discovered that the primary blood-oxygen sensor
is the enzyme heme oxygenase-2 (Prabhakar, et al., Science
Signaling, 2015) and demonstrated that hydrogen sulfide dependent activation of CaV 3.2 low voltage-gated T-type Ca 2+
channels are essential for carotid body O2 sensing (Prabhakar,
et al., American Journal of Cell Physiology, 2015)
• In research relating to obstructive sleep apnea, investigators
found that sympathetic nervous system homeostasis is
dependent on a balance between HIF-1α and HIF-2α, disruption
of which results in hypertension (Prabhakar, et al., Journal of
Physiology, 2014)
Professors
Aasim Padela, MD
Linda Druelinger, MD
(chief)
James Ahn, MD
(associate director, emergency
medicine residency program)
Ying-Jie Peng, MD*
Eric Beck, DO
Willard Sharp, MD
Thomas Fisher, MD
Christine Babcock, MD
(director, emergency medicine
residency program)
Thomas Spiegel, MD
Cai Glushak, MD
Katie Tataris, MD
Murray Keene, MD
Nathan Trueger, MD
Medical Education Fellow
Ira Blumen, MD
David Howes, MD
Ganesh Kumar, PhD*
Jayasri Nanduri, PhD*
Nanduri Prabhakar, PhD
James Walter, MD
David Beiser, MD
Robert Mulliken, MD
Keme Carter, MD
Michael Ward, MD
Michael Paddock, MD
Keegan Checkett, MD
Navneet Cheema, MD
(assistant director, emergency
medicine residency program)
Diane Chaney, MD
Tamara Pilot
Gregg Helland, MD
Teresita Hogan, MD
Steven Lelyveld, MD
Marshall Segal, MD
Vladislav Makarenko, PhD*
Dr. Nathan Seth Trueger
18
Division Distinguished Educator/Mentor (Junior) Award, the
Pritzker School of Medicine’s Leonard Tow Humanism in
Medicine Award and Doroghazi Outstanding Clinical Teaching
Award, and the Emergency Medicine Outstanding Clinical
Teaching Award. Dr. Carter was also appointed as a Junior
Faculty Scholar in the Bucksbaum Institute for Clinical Excellence
• Keegan Checkett, MD—Named to the Curriculum Editorial
Dr. Navneet Cheema
Dr. Keme Carter
• Christine Babcock, MD—Recipient of the Emergency Medicine
In FY 15, six new junior faculty were successfully integrated into
the Section to augment its clinical and educational programs:
Navneet Cheema, MD, is a fellowship trained expert in medical
toxicology who is also serving as assistant emergency medicine
residency program director. Gregg Helland, MD, fellowship
trained in emergency medicine and ultrasound, joined the faculty
as the director of ultrasound, providing oversight of resident
education related to ultrasound. He has conducted research
using chest ultrasound techniques to identify pneumothorax
and to examine ultrasound guided nerve blocks of the lower
extremity. Thomas Speigel, MD, has an MBA in finance, in addition
to an MS in management information systems. Since joining the
faculty as medical director of the adult emergency department,
he focuses his efforts on improving the patient experience,
increasing operational efficiency, and leveraging healthcare
data with predicative analytics and data mining in formulating
long-term strategies for the ED. Katie Tataris, MD, completed her
fellowship training in EMS and disaster medicine with an MPH in
epidemiology. Dr. Tataris is interested in EMS field operations and
the collaboration with mobile integrated healthcare systems.
She has been appointed as the EMS medical director for the
Chicago South EMS System in Region XI. Nathan Seth Trueger, MD,
completed a health policy fellowship at George Washington
University. As a health policy advocate, he is interested in payment
reform, integrated care delivery and the use of social media for
health professions. Michael Ward, MD, has academic interests
focused on medical student and resident education, and ER
management of sepsis. He currently leads an ER initiative to improve
sepsis management and care. In other faculty news, Steven
Lelyveld, MD, retired after 24 years of service to the Section as a
pediatric emergency medicine expert.
emergency medicine training in Tanzania were also made in the
last year. Finally, Keme Carter, MD, was the recipient of several
awards in recognition of her outstanding educational contributions
to the Section, department, medical school and division.
Dr. Michael Ward
19
The Thyroid Study Unit (Samuel Refetoff, MD—director)
continues to work on the identification and treatment of
congenital thyroid diseases, in particular those that cannot be
managed by simple hormone replacement. This year’s highlights
included several advances in thyroid physiology that provided
insights into mutations causing congenital and inherited
diseases, and established criteria for diagnosis, screening and
genetic counseling. For example, laboratory investigations led
to the identification of a TSH mutation in a Pakistani family with
public health implications for the South Asian population (Pappa,
et al.), development of a new therapeutic strategy by AAV-9 viral
vector for MCT8 deficiency (Iwayama, et al.), and discovery of the
first congenital endocrine condition caused by a mutation in an
enhancer (Ferrara, et al.).
Section of
ENDOCRINOLOGY,
DIABETES &
METABOLISM
Dr. Ronald Cohen
One of the unique aspects of the Section is the fully integrated
nature of the adult and pediatric training programs. With two
NIH T32 grants to support training in pediatric endocrinology
research and integrated clinical and basic endocrinology, there
is no other such program in the United States. So far, three
fellows have enrolled in a fully approved program for dual
certification in adult (ABIM) and pediatric (APM) endocrinology,
diabetes and metabolism.
In FY 15, the Section mourned the loss of Donald Steiner, MD,
the A. N. Pritzker Distinguished Service Professor Emeritus of
Medicine and Biochemistry & Molecular Biology. Dr. Steiner
devoted his life to groundbreaking research on diabetes and is
known for his discovery of proinsulin, the precursor of insulin
which is a hormone that helps the body control the use of
sugar. He won international acclaim for his work in diabetes
that facilitated the development of synthetic human insulin
for diabetes therapy, which is now the standard form of clinical
diabetes treatment around the world.
The Sleep, Metabolism and Health Center (Eve Van Cauter, PhD—
director) continues to maintain its status as a leader in cuttingedge sleep research. In FY 15, Dr. Van Cauter was the co-recipient
(with Northwestern) of a new NIH T32 award for training in
circadian and sleep research.
In October 2015, Ronald Cohen, MD, associate professor of medicine, was appointed chief of
the Section of Adult and Pediatric Endocrinology, Diabetes & Metabolism (EDM), where he
previously served in an interim capacity. Dr. Cohen’s appointment reflects his outstanding
leadership, thoughtful academic vision and dedication to the Section.
• Samuel Refetoff, MD—Awarded the 2014 Doctorate Honoris
Causa by the Angel Kanchev University of Ruse in Bulgaria and
the 2015 Department of Medicine Distinguished Service Award
• Ronald Cohen, MD—Named a standing member of the NIH
Molecular and Cellular Endocrinology study section
• George Bakris, MD—Listed as the #1 expert in the world for
hypertension by ExpertScape.com
As a researcher, Dr. Cohen investigates the relationship between
diabetes and adipose tissue, where he is working to develop
novel therapies for the treatment of obesity and type 2 diabetes.
He has developed mouse models to investigate the roles that
a nuclear protein called SMRT (NCoR2) plays in metabolism and
insulin sensitivity. His scholarly work has resulted in over four
dozen published papers and book chapters. Nationally, Dr. Cohen
serves as a standing member of the National Institutes of Health
Molecular and Cellular Endocrinology Study Section, and serves
on the editorial board for the Journal of Biological Chemistry and
Frontiers in Pituitary Endocrinology. He is an active member of the
Endocrine Society, the American Thyroid Association and the
American Diabetes Association, where he has served as chair
for a variety of symposia and on various research committees.
A skilled endocrinologist, Dr. Cohen specializes in the diagnosis
and management of thyroid diseases with a particular focus
on thyroid cancer, and is widely lauded for his outstanding
mentorship and teaching skills.
Under Dr. Cohen’s leadership, the Section developed two new
initiatives in FY 15 relating to its clinical programs. First, the
creation of an outpatient clinic for pediatric and young adult
oncology patients with endocrine complications (Christine Yu,
MD, and Diane Deplewski, MD—co-directors), and second, the
execution of a quality initiative for screening and early detection
of metabolic bone disease in infants in the NICU to reduce
fracture incidence (Dorit Koren, MD—director). This quality
initiative has now been adopted as a standard in the NICU.
The Section’s internationally recognized investigators have
made important scientific contributions that have impacted our
understanding of diabetes, thyroid disease, sleep and polycystic
20
ovary disease. In FY 15, the Section was the recipient of over $8 M
in total grant funding, including a five-year, $1.2 M grant from NIH
awarded to Louis Philipson, MD, PhD, to establish the first type 1
diabetes TrialNet Clinical Center in Chicago. Also new in FY 15
were three NIH-R series awards to Graeme Bell, PhD, to study a
fly model of complex protein misfolding disease in collaboration
with Martin Kreitman, PhD, in the Department of Ecology and
Evolution; Matthew Brady, PhD, to study the impact of chronotype,
obesity and race on circadian genes and fat cells; and Siri
Greeley, MD, PhD, to explore the role of KATP channels in the
brain. David Ehrmann, MD, successfully renewed his NIH Diabetes
Prevention Program outcomes study.
The Kovler Diabetes Center (Louis Philipson, MD, PhD—director)
has clearly established a reputation as a premier destination for
diabetes care and for world-class scientific research. In FY 15,
Dr. Philipson was awarded an NIH grant to establish the first type 1
Diabetes TrialNet Clinical Center in Chicago in partnership with
Advocate Health Care. The goal of TrialNet is to provide patients
throughout Chicago access to cutting-edge studies designed to
prevent and treat diabetes. Also in FY 15, Dr. Philipson expanded
the James C. Tyree Program for Care and Innovation to bring
digital diabetes education resources to the University of Chicago
Medicine Primary Care Clinic. In May 2015. the University of
Chicago Diabetes Research and Training Center (Graeme Bell,
PhD—director) celebrated the 10th Annual Chicago Diabetes
Day. This prestigious meeting serves as a forum for basic and
clinical investigators, clinicians and pharmaceutical industry
personnel in Chicago and the Midwest.
• Rochelle Naylor, MD—Recipient of a new K12 award for her
project entitled, “African Americans’ Perceptions of Diagnostic
Genetic Testing in Diabetes Mellitus”
• Dorit Koren, MD—Appointed to the Ethics Committee of the
Pediatric Endocrine Society
• Christopher Rhodes, PhD—Appointed chair of the Biomedical
Sciences Cluster, University of Chicago
During the past year, Section of Endocrinology, Diabetes &
Metabolism investigators:
• Discovered the first congenital endocrine condition caused
by a mutation in an enhancer (Refetoff, et al., Journal of Clinical
Endocrinology and Metabolism, 2015)
Professors
George Bakris, MD
(director, Hypertension Center)
Graeme Bell, PhD
David Ehrmann, MD
(director, physician directed
practice)
Murray Favus, MD
Samuel Refetoff, MD
(director, Thyroid Study Unit)
Christopher Rhodes, PhD
(chairman, Committee on
Molecular Metabolism and
Nutrition)
Eve Van Cauter, PhD
(director, Center for Sleep and
Metabolism Research)
Louis Philipson, MD, PhD
Tamara Vokes, MD
(director, Kovler Diabetes Center)
(director, fellowship program—
adult; director, 150 E. Huron)
(dean, Division of Biological
Sciences; executive vice
president for medical affairs,
Ronald Cohen, MD (chief)
University of Chicago)
Matthew Brady, PhD
+New FY 16 faculty
• Found that the investigational drug patiromer can reduce
elevated blood-potassium levels in patients with mild or
moderate potassium elevation (Bakris, et al., Journal of the
American Medical Association, 2015)
• Identified a deep intronic INS mutation causing diabetes
through a novel mechanism extending our current
understanding of how diabetes occurring in neonates may have
broader implications for those with insulin deficiency, leading
to diabetes later in life (Greeley, Philipson, Bell, et al., Journal of
Medical Genetics, 2015)
• Determined that silencing mediator of retinoid and thyroid
hormone receptors (SMRT) regulates glucocorticoid effects
on adipocyte metabolic function (Cohen, et al., Molecular and
Cellular Endocrinology, 2015)
• Demonstrated that activity of the endocannabinoid system is
profoundly modulated by circadian rhythmicity, and suggested
that its impact on the regulation of food intake is suppressed
during sleep and is maximal during early to midafternoon
(Hanlon, Van Cauter, et al., Journal of Clinical Endocrinology and
Metabolism, 2015)
Dianne Deplewski, MD
(director, fellowship program—
pediatrics)
Manami Hara, PhD*
Elizabeth Littlejohn, MD
Ann Zmuda, DPM
Decheng Ren, PhD*
Susan Sam, MD
Robert Sargis, MD, PhD
Natalia Tamarina, PhD*
Celeste Thomas, MD
Hongwei Wang, PhD*
Christine Yu, MD
Alexandra Dumitrescu, MD, PhD
Meltem Zeytinoglu, MD+
Siri Atima Greeley, MD, PhD
Clinical A ssociate
Erin Hanlon, PhD*
Dorit Koren, MD
Colleen Flynn Majewski, MD
Rochelle Naylor, MD
David Sarne, MD
Ann M. Leu
Silvana Pannain, MD
21
genetics, celiac disease and pathobiology of GI cancers. The
Section recently received notification that two NIH awards: a
(P01) for the Digestive Disease Research Center, and a (T32) for
research training in digestive health, diseases and nutrition will
be renewed starting in FY 16. These awards will help to ensure
that the Section remains one of the preeminent GI research
programs in the country in the years to come.
Section of
GASTROENTEROLOGY,
HEPATOLOGY &
NUTRITION
Dr. David Rubin
In the educational realm, the Section’s efforts are enhanced
with the continuity of the NIH sponsored T32 training grant and
T35 short-term training awards. The Section is clearly developing
future leaders in the field with 11 fellows in the ACGME GI
fellowship program, as well as additional advanced trainees in
IBD, hepatology, nutrition and interventional endoscopy.
Dr. Andres Gelrud
Under the leadership of David Rubin, MD, the Section of Gastroenterology, Hepatology &
Nutrition joined with the Departments of Surgery and Pediatrics to rebrand the Digestive
Diseases Center as a collaborative, multidisciplinary network of physicians, researchers
and allied health professionals who share a legacy of innovation and a common purpose to
improve the lives of patients who suffer from digestive diseases.
• Recognized as one of top 25 GI programs in the nation by
U.S.News & World Report (July 2015)
Gastrointestinal Endoscopy Leadership Education and
Development (LEAD) program
• Sonia Kupfer, MD—Appointed to the Government Affairs
• Described a new level of “deeper” remission in ulcerative colitis
• Eugene Chang, MD—Recipient of the 2015 Marine Biological
Laboratory Frank R. Lillie Research Innovation Award
• Vani Konda, MD—Appointed to the American Society of
Committee of the American Gastroenterological Society
In FY 15, the Section developed numerous initiatives to grow and
further its vision as the clear leader in academic gastroenterology
in the region, and developed strategic plans for its prominent
clinical programs in liver diseases, inflammatory bowel diseases,
interventional endoscopy and nutrition, while also creating
several new programs in pancreatic diseases, esophageal diseases
and GI cancer risk.
The Nutrition/Small Bowel/Celiac Program (Carol Semrad, MD—
director) provides expert services in collaboration with pediatrics
and continues to perform double balloon enteroscopies, which
are a regional resource for the diagnosis of obscure GI bleeding.
Due to the growth of the program, the Section recruited Edwin
McDonald III, MD, to serve as associate director effective
August 2016.
The Inflammatory Bowel Disease Center (Russell Cohen, MD—
director) continues to be recognized as one of the country’s
largest and most preeminent programs. As a multidisciplinary
center involving over 60 faculty, it facilitates clinical operations,
research and teaching between gastroenterology, surgery,
radiology and pathology. The clinical volume of the IBD Center
continues to grow, with a 4% increase in FY 15, representing over
500 patients seen per month. From a clinical and translational
research standpoint, the clinical IBD group continues to lead
and participate in a large number of NIH- and pharmaceuticalsponsored clinical trials with novel agents. The translational
and basic science group has been successful with an increasing
number of extramural grant awards and high impact publications.
In FY 15, Sonia Kupfer, MD, initiated a GI Cancer Risk and Prevention
Clinic to assess the risks of patients with familial and/or genetic
predispositions to GI cancer. Along with a dedicated genetic
counselor, Jessica Stoll, Dr. Kupfer has seen the demand for this
clinic increase exponentially in its first several months.
The Center for Endoscopic Research and Therapeutics (Irving
Waxman, MD—director) continues to be extremely productive
and has grown at a rate of ~10% per year over the past several
years. Under the direction of Andres Gelrud, MD, a Pancreatic
Disorders Center was established in FY 15 and recently received
designation as a National Pancreas Foundation Center by the
National Pancreas Foundation. The designation recognizes
the Section’s Pancreatic Center as one of the nation’s premier
programs for the treatment of pancreatic diseases. Vani Konda,
MD, is developing new technologies in endoscopic imaging that
can lead to earlier diagnosis and staging of GI cancers.
22
Within the hepatology program, the University of Chicago
Medicine received a $6.2 M grant from the Centers for Disease
Control and Prevention to educate primary care physicians
on the management of hepatitis C in Chicagoland using novel
telehealth technology. Andrew Aronsohn, MD, co-investigator,
has been charged with developing a GI-wide interactive
curriculum that will allow clinicians to engage in case review and
discussion, facilitate surveillance and collect data, along with
using social media to increase awareness and promote testing.
With over $10 M in funding, investigations in IBD, celiac disease
and GI cancer serve as the cornerstone of the Section’s research
programs. Under the direction of Eugene B. Chang, MD, and
Bana Jabri, MD, PhD, the basic/translational research agenda
has clearly established itself as one of the most interactive
institutional programs engaging the combined assets of the
BSD, Marine Biological Laboratory and Argonne National
Laboratory to investigate the role of the intestinal microbiome on
health and disease, gut immune regulation and oral tolerance,
• Determined that diurnal variations in gut microbes and function
• Nancy Reau, MD, and Helen Te, MD—Named as inaugural fellows
in the American Association for the Study of Liver Diseases
During the past year, Section of Gastroenterology, Hepatology &
Nutrition investigators:
• Demonstrated for the first time that a potentially important
are driven by dietary and host cues, and that disturbances of
host-microbe circadian networks may promote diet-induced
obesity. These findings may provide opportunities for unique
and targeted interventional strategies to treat and prevent diet
induced obesity, ranging from the manipulation of gut microbial
function to pharmacological targeting of host pathways to restore
metabolic balance (Chang, et al., Cell Host and Microbe, 2015)
patients, which involved reviewing the histology of patients
undergoing surveillance colonscopies, and identifying that
approximately 10% of these patients “normalized” their bowel
mucosa, a previously unknown possibility in ulcerative colitis.
These patients have more stable remission than patients without
such histologic normalization (Christensen, et al., presented at
Digestive Disease Week, Washington DC, 2015)
component of Vitamin D chemoprevention is mediated by VD
suppression of the renin-angiotensin axis (Bissonnette, et al.,
Clinical Cancer Research, 2014)
Professors
David T. Rubin, MD
(chief and co-director of
Digestive Diseases Center)
Marc Bissonnette, MD
Eugene B. Chang, MD
(associate section chief
for research)
Russell Cohen, MD
(director, IBD Center)
Ira Hanan, MD
(medical director)
Bana Jabri, MD, PhD
(vice chair, basic research)
Andres Gelrud, MD
(director, Pancreatic
Disorders Center)
Yanchun Li, PhD
Sonia Kupfer, MD
(director, GI Cancer Risk and
Prevention Clinic)
Edwin McDonald III, MD+
Atsushi Sakuraba, MD
Uzma Siddiqui, MD
Leslie Wallene Yang, MD
Helen Te, MD
(medical director, liver transplant)
Feng Wu, PhD*
Neil Sengupta, MD+
Andrew Aronsohn, MD
(director, telehealth initiative)
Andreas Mykoniatis, MD
Mark Musch, PhD*
Sushila Dalal, MD
Carol Semrad, MD
(director, nutrition and small
bowel program)
Murat Eren, PhD+
Irving Waxman, MD
(director, Center for Endoscopic
Research and Therapeutics)
+New FY 16 faculty
Xiaorong Zhu, PhD*
Karen Kim, MD
(dean for faculty affairs)
Robert Kavitt, MD
(director, Esophageal Center)
Keith Naylor, MD
Mark Mitchell
Joel Pekow, MD
(interim director, translational core)
Kapuluru Gautham Reddy, MD
Yong Huang, PhD*
Bertram Rogers, MD
(C o - a p p o i n t m e n t w i t h A N L )
Dionysios Antonopoulos, PhD
Folker Meyer, MD
Vani Konda, MD
23
healthcare providers in cultural competence and in motivating
patients for healthy behavior change. This work has demonstrated
significant improvements in diabetes outcomes, with these
innovations incorporated into regular practice over time, and a
healthier South Side population.
Section of
GENERAL
INTERNAL
MEDICINE
The Section’s talented faculty represent the core teaching
leadership for the University of Chicago, with many senior
members and fellows in the Academy of Distinguished Medical
Educators and the Bucksbaum Institute for Clinical Excellence,
and significant roles in the Pritzker School of Medicine. Faculty
also coordinate significant collaborative teaching efforts for
Dr. Deborah Burnet
The Section of General Internal Medicine (GIM) is home to a highly talented faculty who
are dedicated to providing excellent clinical care while conducting impactful research that
spans the areas of medical education, bioethics, population health, healthcare disparities
and outcomes, patient safety and quality improvement. Section faculty are recognized for
their outstanding leadership in the field, and for their significant contributions to medical
education and outreach programs on the South Side of Chicago and beyond.
Additionally, GIM houses many outstanding multidisciplinary
academic centers and programs, including the MacLean Center
for Clinical Medical Ethics (Mark Siegler, MD—director), Program
on Religion and Medicine (Daniel Sulmasy, MD—director), Chicago
Center for Diabetes Translation Research (Marshall Chin, MD;
Deborah Burnet, MD; Elbert Huang, MD; and Monica Peek, MD—
directors), RWJF Finding Answers: Disparities Research for
Change (Marshall Chin, MD—director), and the Center for
Translational and Policy Research for Chronic Diseases (Elbert
Huang, MD—director). Noteworthy in FY 15 were the appointments
of three new faculty to enhance these programs. Audrey
Tanksley, MD, assistant professor of medicine, is developing a
new curriculum for teaching informed consent processes to
trainees to optimize patient-centered care. Mara Terras, MD,
assistant professor of medicine, is developing an integrated-care
model for mental health screening, treatment and monitoring in
the primary care setting. George Weyer, MD, assistant professor
of medicine, serves as the associate director for population
health and is supporting the Section’s transition to value-based
care and new managed care contracts.
The Primary Care Group (PCG) (Lisa Vinci, MD—director) cared
for approximately 22,000 patients, with approximately 58,000
patient encounters during the academic year. In FY 15, the PCG
significantly expanded the care management programs to
include behavioral health services through a new partnership
with psychiatry. Psychiatrists, psychologists and social workers
now see patients in the PCG to support healthy behavior
change and teach trainees how to integrate care for psychosocial needs. The PCG also assumed three new managed care
contracts. The Anti-Coagulation Management Service (Irsk
Anderson, MD—director) expanded significantly by offering
care for patients from cardiology, vascular surgery and some
24
Pritzker School of Medicine students and community clinics
such as CommunityHealth in the Englewood neighborhood. New
in FY 15 was the creation of a national leadership development
program for academic general internists through the Society
of General Internal Medicine. Led by Dr. Burnet, the SGIM LEAD
program had ten participants from peer institutions around the
country in its first year, with 15 entering its second-year program.
With funding from the Health Resources Service Administration,
Dr. Burnet will begin a new leadership training program in FY 16
for urban primary care education and transformation.
patients with sickle cell disease. Plans for FY 16 include working
with hematology/oncology, neurology, and transplant surgery to
further expand anti-coagulation services.
In FY 15, the Section’s research portfolio totaled approximately
$6 M in funding, representing a broad spectrum of innovative
investigations. New this year was an NIH R01 awarded to Vineet
Arora, MD, to educate hospital staff on how to improve sleep
among hospitalized patients. Elbert Huang, MD, was the recipient
of funding from the Helmsley Charitable Trust to develop an
innovative clinical care approach for young adults with type 1
diabetes, and Marshall Chin, MD, and Monica Peek, MD, received
renewal funding from the Merck Foundation in support of their
work to improve diabetes care and outcomes on the South Side
of Chicago. Dr. Peek was also selected as a Greenwall Foundation
Bioethics Scholar for her research focused on diabetes health
disparities on Chicago’s South Side. Neda Laiteerapong, MD, was
awarded a UC Innovations grant in partnership with colleagues
from the Booth School of Business to study new models of
screening for mental health conditions.
The Section is dedicated to the development and implementation
of community-based outreach programs to build communitypartnered research and education. To strengthen that mission,
new this year was the appointment of Monica Peek, MD, as
the UCM executive medical director of community health
innovation. In this role, she will be responsible for transitioning
successful innovations from research into clinical practice. Over
the past five years, Drs. Monica Peek and Marshall Chin have led
the diabetes care and outcomes initiative which brings together
six practices (four community health centers and two academic
clinics), to improve care and outcomes for patients with
diabetes. Drs. Burnet, Michael Quinn and Karen Kim coach
• Mark Siegler, MD—Recipient of the 2015 Department of
• Andy Davis, MD, and Adam Cifu, MD—Appointed as deputy • Marshall Chin, MD—Installed as president of the Society for
• GIM faculty published JAMA Guideline Synopsis reviews on the • Scott Stern, MD; Adam Cifu, MD; and Diane Altkorn, MD—
• Found a strong association between patient-centered medical
Medicine Distinguished Service Award, designated as a Master of the American College Physicians, and accepted the John Conley Foundation Award for Outstanding Contributions to Clinical Ethics Education
General Internal Medicine
editors of Journal of the American Medical Association (JAMA) for
a new series on clinical guideline synopses and authored several reviews on lung cancer screening and use of HPV vaccine in males and females
following topics: Cervical cancer screening (Volerman, Cifu, 2014); Screening for asymptomatic carotid artery stenosis • Daniel Sulmasy, MD, PhD—Appointed to the prestigious board of (Weyer, Davis, 2015); Screening for abdominal aortic aneurysm the Greenwall Foundation Bioethics Scholars Program
(Bird, Davis, 2015); Screening for hepatitis C (Wray, Davis, 2015)
• Vineet Arora, MD—Recipient of the Society of General Internal
During the past year, Section of General Internal Medicine
Medicine’s Frederick L. Brancati Mentorship and Leadership
investigators:
Award, and the John D. Arnold Mentorship Award from Pritzker
School of Medicine. She was also named to the board of
• Found that the standard measures of diabetes care in the United
directors for the American Board of Internal Medicine
States underestimate racial and ethnic disparities when monitoring
a patient’s blood sugar and other clinical indicators, and could
• Scott Stern, MD—Recipient of the Department of Medicine’s
mean management of the disease in the country is actually
Clinical Teacher of the Year Award
worsening (Laiteerapong, Chin, Huang, et al., Medical Care, 2015)
• Ann Hong, MD—Recipient of the Department of Medicine’s
• Conducted the first study of the epidemiology of remission in
Medical Resident Teaching Award
type 2 diabetes in adults not treated with bariatric surgery which
• Arshiya Baig, MD—Recipient of the Midwest SGIM Advocacy and showed that remission is rare and variable (Huang, et al.,
Community Service Award
Diabetes Care, 2014)
Published the third edition of their textbook, Symptom to
Diagnosis: An Evidence-Based Guide (McGraw Hill)
home characteristics and support for patient activation in the
safety net; the PCMH model may also reduce racial and ethnic
health disparities (Chin, et al., Medical Care, 2014)
Professors
Anna Volerman Beaser, MD
Deborah Burnet, MD, MA
(chief)
Vineet Arora, MD, MA
Irsk Anderson, MD
George Weyer, MD
Diane Altkorn, MD
Dionne Blackman, MD
Arshiya Baig, MD, MPH
Andrew Davis, MD, MPH
Chia-Hung Chou, PhD*
Susan Glick, MD
Kamala Cotts, MD
Susan Hong, MD, MPH
Anne Hong, MD
Elbert Huang, MD, MPH
Neda Laiteerapong, MD
Patricia Kurtz, MD
Wei Wei Lee, MD
Doriane Miller, MD
Amber Pincavage, MD
Julie Oyler, MD
Yasmin Sacro, MD
Monica Peek, MD, MPH
Sachin Shah, MD
Rita Rossi-Foulkes, MD, MS
Todd Stern, MD
Monica Vela, MD
Audrey Tanksley, MD
Cindy Kitching
Lisa Vinci, MD, MS
Mara Terras, MD
Halina Brukner, MD
Marshall Chin, MD, MPH
Adam Cifu, MD
Mindy Schwartz, MD
Mark Siegler, MD
Scott Stern, MD
Daniel Sulmasy, MD, PhD
James Woodruff, MD
Joseph Asbury, MD
William Harper, MD
Ari Levy, MD
Alex Lickerman, MD
Kristen Lipstreuer, MD
Ashley Martin, MD
Katarina Veskovic, MD
25
Section of
Dr. Nicolae also furthered his genome-wide association studies
of rare and low-frequency variants in asthma in ethnically
diverse populations. Progress continued in the established
Silvio O. Conte Center (Andrey Rzhetsky, PhD—director) where
computational data-mining has been applied to understand
the causes of neuropsychiatric disorders, and Dr. Perera
strengthened her participation in the Warfarin Consortium.
GENETIC
MEDICINE
Dr. Dan Nicolae
On January 1, 2015, Dan Nicolae, PhD, was appointed interim chief of the Section of Genetic
Medicine. He succeeds Nancy Cox, PhD, who retired from the Department of Medicine in
FY 15. During her tenure, the Section witnessed remarkable success, and matured into one
of the Department’s most active and collaborative groups focused on developing new and
more powerful ways to identify genetic risk factors for common and complex disorders.
Under Dr. Nicolae’s leadership, the Section continues to evolve into the central intellectual
unit for translational genetics research and the development of computational science in
the Department of Medicine and BSD.
Dr. Andrey Rzhetsky
Dr. Barbara Stranger
Dr. Minoli Perera
Dr. Nicolae currently serves as professor of medicine, statistics
and human genetics and as a senior fellow in the Computation
Institute. A leader in statistical and human genetics, Dr. Nicolae
has made major contributions to the understanding of complex
diseases. His interdisciplinary research is centered on deciphering
the role of genetic variation and environmental factors and their
interactions in human traits. His work covers problems on the full
spectrum of research in this field, from theoretical statistics to
data analysis. He has made significant discoveries relating to the
genetic and environmental components of asthma and related
phenotypes, and diabetes and its complications, and he has been
centrally involved in major developments and contributions to
the understanding of these diseases over the past decade. He is
also credited with creating analytic solutions that allowed the
discovery of important disease genes, such as NOD2 and IL23R
for Crohn’s disease. Dr. Nicolae’s work has led to over 100 peer
reviewed articles, and he serves as co-PI or project leader on
several NIH funded projects .
With an FY 15 research portfolio of over $19 M in total costs, the
Section conducts impactful investigations focused on quantitative
genetics, systems biology and genomics, bioinformatics and
computational biology. New in FY 15 were two awards: a large
federal grant awarded to Andrey Rzhetsky, PhD, from the federal
Defense Advanced Research Projects Agency to integrate machine
reading of cancer literature to increase knowledge about cancer
mechanisms and practical cancer therapies, and an NIH R01 awarded
to Minoli Perera, PhD, focused on identifying liver-specific eQTLs
in African Americans for drug metabolizing enzymes with the
potential for wide-spread scientific and clinical impact given the
dearth of such studies in African Americans to date.
26
Several other high-impact projects were ongoing in FY 15. Robert
Grossman, PhD, focused on the development and operation
of an Open Genomics Data Commons (OGDC) as a result of a
three-year multi-million dollar grant from the NCI awarded last
year, while Barbara Stranger, PhD, centered her investigative
efforts on the NIH/National Human Genome Research
Institute cooperative agreement (U01) to measure the levels
of approximately 1,500 cell signaling and transcription factor
• Barbara Stranger, PhD—Appointed to the editorial board of
PLoS Genetics
• Minoli Perera, PhD—Recipient of the Leon Goldberg Early
Investigator Award from the American Society of Clinical
Pharmacology Therapeutics and selected to participate in the
AAMC Early Career Women Faculty Professional Development
Leadership training
During the past year, Section of Genetic Medicine investigators:
• Provided new insights into how genomic variants control how,
when and how much genes are turned on and off in different
tissues, and predispose people to diseases (GTEX
Consortium, Nicolae, et al., Science, 2015)
• Conducted the largest study to date to assess the effects of rare
• Identified specific genetic polymorphisms that explain differences
among individuals in response to pathogens to help us understand
the degree to which immune responses are driven by the
environment or by an individual’s physiological or genetic
factors (Ye, Stranger, et al., Science, 2014) and provided important
insights on how genetic variants have effects on gene
expression in immune cells (De Jager, Stranger, et al., Seminars in
Immunology, 2015)
• Examined the effect of rs7089580 in warfarin metabolism and
CYP2C9 expression levels in African Americans, proving that
identifying polymorphisms that affect expression levels and
metabolism across ethnicities is essential for individualization
of doses with a narrow therapeutic index (Perera, et al.,
Translational Research, 2015)
variants on asthma risk in ethnically diverse individuals and made • Showed that a Mendelian disease and comorbid cancer have
new discoveries in the genetics of asthma and related
genetic alterations of significant functional similarity providing
phenotypes (Ober, Nicolae, et al., Nature Communications, 2015 & a novel way to discover new cancer genes (Melamed, Rzhetsky,
Human Molecular Genetics, 2015)
et al., Nature Communications, 2014)
Dr. Robert Grossman
proteins in five unique tissues to pinpoint proteins and protein
networks that underlie complex human traits and disease.
The GTEx project, with one of the methodology development
groups led by Dr. Nicolae, continued to generate new data for
characterizing genetic variants implicated in transcriptome
regulation, disease susceptibility and pharmacogenomics.
Professors
Dan Nicolae, PhD
(interim chief)
Hae Kyung Im, PhD*
Robert Grossman, PhD
Minoli Perera, PhD
Ann Leu
Andrey Rzhetsky, PhD
Barbara Stranger, PhD
27
Section of
GERIATRICS &
PALLIATIVE
MEDICINE
Dr. William Dale
The Section of Geriatrics & Palliative Medicine (GPM) continues to be recognized nationally
for its outstanding programs in geriatrics clinical care, education and research and has
rapidly established a national reputation in palliative medicine as well. Under the leadership
of William Dale, MD, PhD, GPM continues to expand its programs in the areas of inpatient
palliative medicine, frailty, geriatric-oncology, medical decision-making, transitions of care,
geriatric-nephrology, multimorbidity and pain assessment. These efforts mirror the Section’s
standing as one of 28 John A. Hartford Centers of Excellence in Geriatrics in the country.
As the largest independent section/division of geriatrics and
palliative medicine in Chicago, GPM continues to achieve
substantial success across its key programs: South Shore
Senior Center, SOCARE Geriatric-Oncology Clinic, palliative
medicine program, frailty (Successful Aging for Frail Elders
[SAFE] Clinic), care transitions (TraCCE program) and geriatric
nephrology. In FY 15, GPM transitioned to a new supportive
care unit, a multidisciplinary model to care for patients, mainly
from hematology/oncology, who are hospitalized primarily
for symptom management, rather than for cancer-directed
treatment. Working closely with the inpatient palliative care
consult service, different care teams round daily and provide
trainees with a true multi-disciplinary learning experience.
Preliminary data from this patient care model suggest
significantly shorter lengths of stay for these patients and
reduced daily costs. In outpatient programs, the nationally
recognized SAFE Clinic (Katherine Thompson, MD, and Megan
Huisingh-Scheetz, MD—co-directors), continued to provide
comprehensive geriatric assessment and frailty evaluation to
older patients as well as serve as platform for research and
teaching efforts. The Specialized Oncology Care & Research in
the Elderly (SOCARE) clinic (Dr. Dale and James Wallace, MD—
co-directors) continues to grow in terms of volume, national
recognition and funding activity and serves as a model for similar
embedded endeavors, both internally (i.e. palliative care clinic,
geriatric nephrology clinic), and externally at the University of
Toronto, Medical College of Wisconsin, the University of Virginia
and in Dublin, Ireland. Finally, the Transitions of Coordinated Care
for the Elderly (TraCCE) network, designed to improve outcomes
for elderly patients who are transferred from the hospital to
the “post-acute area” of a nursing home, has seen considerable
improvement in terms of patient outcomes.
28
In FY 15, the GPM welcomed two
new faculty members: Charles
Rhee, MD, and Selina Chow, MD.
Dr. Rhee, assistant professor
of medicine, is the second
palliative medicine specialist
in the Section. Along with a
clinical program embedded in
hematology/oncology, Dr. Rhee
is developing collaboration
with the heart failure team in
cardiology to help care for
patients with ventricular assist
devices. Dr. Chow, clinical
Dr. Charles Rhee
associate, is the first oncologist
in GPM. She focuses her efforts on geriatric oncology alongside
Drs. Dale and Wallace in the SOCARE clinic, and in the
hematology/oncology clinic, the South Shore Senior Center and
oncology patients in nursing home settings.
Research efforts by GPM faculty and research staff continue to
be supported by a variety of external sources, including NIA, NCI,
CMS, HRSA, the Norwegian government, the Hartford Foundation
and the Coleman Foundation, among others. In FY 15, Katherine
Thompson, MD, received notification from the Health Resources
and Service Administration (HRSA) that her application to
develop a geriatrics workforce enhancement program will be
funded for three years. This program aims to develop a health
care workforce that will improve health outcomes for older adults
by integrating geriatrics with primary care, maximizing patient
and family engagement, and transforming the health care system.
In the educational realm, the palliative medicine fellowship
program (Stacie Levine, MD—program director) is considered
one of the best programs in the Midwest. In addition, Dr. Levine
serves as co-PI of an award funded by the Coleman Foundation,
(in collaboration with Rush University Medical Center), to teach
palliative medicine to other medical sub-specialties throughout
the Chicagoland area. This program has garnered so much success
in its first year that the Coleman Foundation has agreed to fund
this impactful educational program for three additional years.
Dr. Stacie Levine
Dr. Katherine Thompson
Dr. Selina Chow
• Megan Huisingh-Scheetz, MD—Awarded the 2015 Presidential
• Developed guiding principles for clinical decision-making and
• Katherine Thompson, MD—Graduate of the 2014 Harvard Macy • Provided insights on effective pain management for older
Poster at the American Geriatrics Society meeting for her project
entitled “Screening for Frailty in Thoracic Surgery Patients”
Program for Educators in the Health Professions
During the past year, Section of Geriatrics & Palliative Medicine
investigators:
management for complex, multimorbid elderly cancer
patients (Thompson, Dale, Journal of Geriatric Oncology, 2015)
adults with management focusing on the initiation and
monitoring of commonly used analgesics (Malec, et al.,
Medical Clinical of North America, 2015)
• Conducted an interprofessional medication management
workshop for trainees to potentially reduce adverse events and acute care use through improved medication management in older adults (Kostas, et al., Journal of the American Geriatrics Society, 2014)
Secondar y Appointments
William Dale, MD, PhD
(chief)
Kellie Campbell, MD, MA
(medical director,
South Shore Senior Center)
Stacy Lindau, MD, MPH
Daniel Brauner, MD
(director of long term care)
Stacie Levine, MD
(director of education,
co-director of palliative medicine)
Megan Huisingh-Scheetz, MD, MPH
(chief, geriatrics, Mercy Hospital)
Tia Kostas, MD
Monica Malec, MD
Charles Rhee, MD
Katherine Thompson, MD
Shellie Williams, MD
Tamara Konetzka, PhD
A ssociate Members
Andrea Bial, MD
(Horizon Hospice)
Joanna Martin, MD
(medical director, Horizon Hospice)
Bradford Lane
Clinical A ssociate
Selina Chow, MD
29
Professors
Walter Stadler, MD
(chief)
Houda Alachkar, PhD*
of Science
Michael Bishop, MD
• Michelle Le Beau, PhD—Recipient of the Biological Sciences Division’s
Suzanne Conzen, MD
Jane Churpek, MD
• Olufunmilayo Olopade, MD—Elected to the Nigerian Academy
Section of
HEMATOLOGY/
ONCOLOGY
Distinguished Faculty Award for Leadership and Good Citizenship
and elected to the national board of directors of the Leukemia &
Lymphoma Society
• Philip Hoffman, MD—Recipient of the Department of Medicine’s
Preclinical Teacher of the Year Award
Dr. Walter Stadler
• Blase Polite, MD—Recipient of the Biological Sciences Division’s
Over the past year, several faculty were recognized for their
outstanding academic contributions. Wendy Stock, MD, was
honored as the Anjuli Seth Nayak Professor in Leukemia. Dr. Stock
is a preeminent clinical and translational researcher who has made
seminal contributions to the understanding and treatment of
hematologic malignancies, in particular for her discovery of novel
therapies for the treatment of acute lymphoblastic leukemia in
adolescents and young adults. Olufunmilayo Olopade, MD, was
selected as the recipient of the Franklin D. Roosevelt Freedom
from Want Medal, while Mark Ratain, MD, was chosen for the
2015 Award in Excellence in Clinical Pharmacology from the
Pharmaceutical Research and Manufacturers of America Foundation.
In FY 15, Jason Luke, MD, assistant
professor of medicine, joined
the Section. Dr. Luke’s research
focuses on translational
therapeutic advances for
melanoma and early phase
drug development, particularly
immunotherapy and targeted
molecular therapies for melanoma
and advanced cancer.
In the clinical arena, the
Dr. Jason Luke
ambulatory oncology practice
(Chadi Nabhan, MD—director) successfully completed the
ASCO Quality Oncology Practice Initiative and received threeyear certification in recognition of the Section’s outstanding
patient care and ongoing quality improvement in the clinic. In
FY 15, Section faculty were responsible for over 46,000 clinic
visits (+ 2% from FY 14 ) and nearly 30,000 outpatient IV therapy
encounters. The bone marrow transplant program (Michael
Bishop, MD—director) performed 188 transplants (+12% from FY
14) and successfully conducted the first outpatient bone marrow
transplant. Also noteworthy was the 15% increase in visits for
30
the multiple myeloma program (Andrzej Jakubowiak, MD, PhD—
director). The Section’s joint venture with Silver Cross Hospital
continues to be successful with a 20% increase in patient visits as
compared to FY 14.
New grants in FY 15 include a large NIH R01 awarded to Michael
Maitland, MD, PhD, to develop a prototype tool that will enhance
the efficiency of cancer clinical trials, and a NIH Translational
Scholar in Pharmacogenomics and Personalized Medicine (K23)
award to Manish Sharma, MD, to develop genomic prediction
tools to personalize the treatment plan for cancer patients
and ultimately improve outcomes. Daniel Catenacci, MD, was
also awarded an NIH K23 to conduct a pilot trial of personalized
therapeutics for gastroesophageal adenocarcinoma and
Suzanne Conzen, MD, was awarded a high-impact team science
grant from the Prostate Cancer Foundation to study the use of
selective glucocorticoid receptor antagonists in castrationresistant prostate cancer. Clinical research in the Section is
similarly active, with organized multidisciplinary treatment
groups in each major malignancy that conduct nearly 300
therapeutic clinical trials with enrollment of over 700 patients
annually. The Section continues to be one of only three cancer
programs in the United States with NCI core support for all
phases of clinical trials (I, II and III).
Within the educational realm, the hematology/oncology
fellowship program (Kenneth Cohen, MD—director) continues
to be successful in training the next generation of leaders in
oncology. The Section continues to recruit highly qualified
candidates, all from very competitive programs. The Section
also holds two NIH T32 grants, one for oncology training
(Olufunmilayo Olopade, MD—director) and one for clinical
pharmacology with a focus on cancer pharmacology (Eileen
Dolan, PhD, and Mark Ratain, MD—co-directors). Dr. Olopade
also successfully renewed a K12 institutional training grant for
developing the careers of early junior faculty.
M. Eileen Dolan, PhD
(chair, Committee on
Pharmacology and
Pharmacogenomics)
Kenneth Cohen, MD
Jonas De Souza, MD
Olwen Hahn, MD
Yoo-Jeong Han, PhD*
Rifat Hasina, PhD*
Rong Stephanie Huang, PhD
Justin Kline, MD
Distinguished Clinician Award
Gini F. Fleming, MD
Tanguy Lim-Seiwert, MD
• Justin Kline, MD—Appointed as a permanent member to the National
Thomas F. Gajewski, MD, PhD
Hongtao Liu, MD, PhD
Lucy A. Godley, MD, PhD
Jason Luke, MD
Harvey M. Golomb, MD
Michael Maitland, MD, PhD
Philip Hoffman, MD
(associate chief for
appointments and
promotions)
Rita Nanda, MD
Cancer Institute’s Subcommittee J
The Section of Hematology/Oncology has a long history of national and international
prominence. Under the direction of Walter Stadler, MD, Section faculty continue to make
impactful contributions to cancer care, research and training. The Section’s research programs
in basic, translational and clinical research are flourishing with a total cost funding portfolio
of over $18 M. On the inpatient side, the Section, in collaboration with the Section of
Geriatrics & Palliative Medicine, opened a 16-bed supportive care unit in Mitchell Hospital.
Christopher K. Daugherty, MD
(chair, Institutional Review
Board)
Daniel Catenacci, MD, PhD
• Rita Nanda, MD—Recipient of the National Cancer Institute’s Clinical
Investigator Team Leadership Award and the Department of
Medicine’s Patient Satisfaction Award
• Victoria Villaflor, MD—Recipient of the Department of Medicine’s
Productivity Award for Patient Visits
During the past year, Section of Hematology/Oncology investigators:
• Explored factors that may contribute to the racial survival disparity
in breast cancer (Olopade, et al., Cancer: A Cancer Journal for
Clinicians, 2015 and JAMA, 2015)
• Reported germline ETV6 mutations in familial thrombocytopenia
and hematologic malignancy and identified a central role for ETV6 in
haematopoiesis and malignant transformation (Zhang, Churpek,
Godley, et al., Nature Genetics, 2015)
• Identified replication stress as a potent driver of functional
decline in old haematopoietic stem cells and highlighted the mini chromosome maintenance DNA helicase as a potential molecular
target for rejuvenation therapies (Flack, Le Beau, et al., Nature, 2014)
• Determined that a liposomal TOPK inhibitor may be a promising
molecular-targeted therapy, which could improve the clinical outcome
of breast and lung cancer patients who have tumors with high TOPK
expression (Nakamura, et al., Science Translational Medicine, 2014)
• Identified and validated genetic variants that influence transcription
factor and cell-signaling protein levels (Hause, Dolan, et al., American
Journal of Human Genetics, 2014). This publication earned the ASHG
Cotterman Award for outstanding scientific contributions to the
field of human genetics from the journal
• Found that adding ovarian suppression to tamoxifen for women who
Andrzej Jakubowiak, MD, PhD
Hedy L. Kindler, MD
Richard A. Larson, MD
Michelle M. Le Beau, PhD
(director, University of
Chicago Comprehensive
Cancer Center)
Yusuke Nakamura, MD, PhD
(director, Center for Clinical
Cancer Genetics and
associate dean for global
health)
Mark J. Ratain, MD
(director, Center for
Personalized Therapeutics)
Peter O’Donnell, MD
Jae-Hyun Park, PhD*
Gordana Raca, MD, PhD
Cara Rosenbaum, MD
Shaun Rosebeck, PhD*
Manish Sharma, MD
Russell Szmulewitz, MD
Aparna Vasanthakumar, PhD*
Yonglan Zheng, PhD*
Kwang Jin Choi, MD
Abubha Ganjoo, MD
Ehtasham Khattak, MD
Tu Mai, MD
Sunila Narula, MD
Sandipkumar Patel, MD
Ravi Salgia, MD, PhD
(vice chair for translational
research)
Brooke Phillips, MD
Wendy Stock, MD
Samir Undevia, MD
Everett Vokes, MD
(chair, Department of
Medicine)
Amittha Wickrema, PhD
Lawrence Schilder, MD
Grace Suh, MD
James Wallace, MD
Andrea Amico, MD
Emily Curran, MD
Mark Kozloff, MD
were at risk for recurrence of breast cancer improved disease outcomes
(Francis, Fleming, Kindler, et al., New England Journal of Medicine, 2015)
Andrew Artz, MD
• Demonstrated that an activated β-catenin pathway can inhibit
William Dale, MD, PhD
Ryuji Hamamoto, PhD*
Vassiliki Saloura, MD
successful PD1 pathway directed immunotherapy in melanoma
(Spranger, Bao, Gajewski, Nature, 2015)
• Predicted a response to histone deacetylase inhibitors using
high-throughput genomics (Huang, et al., Journal of the National
Cancer Institute, 2015)
Joseph M. Baron, MD
Thomas Hensing, MD
Erica Stringer, MD
Mark Lingen, DDS, PhD
Chadi Nabhan, MD
Jerry Schissler
Olatoyosi M. Odenike, MD
Blase N. Polite, MD, MPP
Angela Stoddart, PhD*
Sonali M. Smith, MD
Michael J. Thirman, MD
Victoria Villaflor, MD
Todd M. Zimmerman, MD
Dr. Wendy Stock
31
Section of
HOSPITAL
MEDICINE
Dr. John Yoon
Dr. David Meltzer
Dr. Brian Callender
Dr. Shalini Reddy
Dr. Jeanne Farnan
• David Meltzer, MD, PhD—Appointed an economic advisor to
Led by David Meltzer, MD, PhD, the Section of Hospital Medicine is comprised of faculty,
advanced practice nurses and physician assistants who are dedicated to caring for
hospitalized patients. The faculty and staff have emerged as national leaders in clinical
practice, research and medical education within the field. In FY 15, the Section continued to
enhance its growing inpatient programs at University of Chicago Medicine.
Under the direction of Dr. Meltzer and the director of clinical
operations Marius Chivu, MD, the Section developed a stable
staffing model to address the near doubling of clinical volumes
that resulted from the opening of the Center for Care and
Discovery (CCD) in 2013. Through the efforts of Section faculty,
the Department and UCM leadership, this goal was achieved
by creating a Short Stay Unit and an Advanced Practice Service
(Tipu Puri, MD, PhD; Brian Callender, MD; and Madhu Yarlagadda
MD—directors) to expedite care delivery and improve patient
outcomes. Other new initiatives in FY 15 include the launch of the
eCART algorithm developed by Dana Edelson, MD, and Matthew
Churpek, MD, PhD, for clinical use by the critical care outreach
team to risk stratify patients for proactive rounding and automate
rapid response team calls in the CCD.
32
help government and other
policy makers improve health
outcomes, particularly for poor
and vulnerable urban residents.
The comprehensive care physician (CCP) program continued to
expand during the academic year. To date, over 1,500 patients
have been enrolled in the study, with 2,000 expected by spring
2016. The CCP model seeks to improve care and lower costs
by increasing continuity of care and strengthening the bond
between doctor and patient, and is supported by a large Health
Care Innovation award from the Center for Medicare & Medicaid
Innovation (David Meltzer, MD, PhD—PI).
The Section’s funding portfolio
consisted of over $6 M in
extramural funding in FY 15,
including two new grants
awarded to Dr. Meltzer: an
NIH K12 to develop a patientcentered outcome research
training program; and a large
grant from the George E.
Dr. Joyce Tang
Richmond Foundation to
develop a program in oral health, systemic health, well-being
and the social sciences. William Padula, PhD, was also awarded a
NIH F32 for his project entitled, “Using EHR Data to Dynamically
Target Patients for Braden Scale Risk-Assessment.” Within the
Center for Health Statistics, Robert Gibbons, PhD, received a
new subaward to develop an adaptive, personally tailored and
evidence-based suicide risk screen and triage protocol for youth
seeking Emergency Department services.
In FY 15, Joyce Tang, MD, joined the faculty with direct efforts
focused on the CCP program. Dr. Tang’s research interests focus
on developing patient-centered approaches to improving
population health by integrating both quantitative and qualitative
methods to understand the perspectives of patients, providers
and other stakeholders. Other noteworthy faculty news in FY 15
includes Dr. Meltzer’s election to the prestigious Association of
American Physicians in recognition of his outstanding work in
medical cost-effectiveness analysis and the costs and quality of
hospital care. Dr. Meltzer was also appointed director of the
University of Chicago Health Urban Labs, where he will lead efforts
to leverage scholarship, data and community relationships to
Hospital Medicine faculty are also actively engaged in teaching
and training of the next generation of physicians and physician
scientists at the medical school, residency and at the post graduate
level. In FY 15, Jeanne Farnan, MD, was appointed assistant dean
for curricular development and evaluation in the Pritzker School
of Medicine. Other leadership roles in the medical school
include track leader for global health scholarship and discovery
(Brian Callender, MD), director and assistant program director
of the internal medicine residency program at Mercy Hospital
(Shalini Reddy, MD, and John Yoon, MD), and director of the MD/
PhD program in the social sciences and chair of the committee
on clinical and translational science (David Meltzer, MD, PhD).
the NIH Director’s Office, recipient of the Department of
Medicine’s Arthur Rubenstein Mentorship Award and recently elected to the prestigious National Academy of Medicine
• Robert Gibbons, PhD—Appointed as an advisor to the Director
of NIH, Dr. Francis Collins
• Jeanne Farnan, MD—Recipient of the 2015 LDH Wood Award
for Pre-Clinical Teacher of the Year from the Pritzker School
of Medicine
• Shalini Reddy, MD—Recipient of the Clerkship Directors in
Internal Medicine’s Charles H. Griffith, III, MD Education
Research and Education Scholarship Award and elected to the
faculty advisory committee of the Biological Sciences Division
• Developed an accurate ward risk stratification tool using
commonly collected electronic health record variables to
identify high-risk ward patients and improve intensive care
unit triage decisions (Churpek, Edelson, Meltzer, Gibbons, et al.,
American Journal of Respiratory and Critical Care Medicine, 2014)
• Demonstrated the validity of the use of standardized videos to
measure the quality of patient handoff (Arora, Farnan, et al.,
Journal of Hospital Medicine, 2014)
• Identified physician thoroughness as the most important
attribute associated with increased satisfaction with care in a
national survey of patient satisfaction (Tak, Ruhnke, Shih, Patient
Centered Outcomes Research, 2015)
• Published a book entitled,
“Statistical Methods for Drug Safety,” describing cutting-edge pharmacoepidemiologic techniques for the analysis of drug safety data (Gibbons, Amatya, CRC Press, 2015)
• Valerie Press, MD—Recipient of the SGIM Frederick L. Brancati
Leadership Scholar
• Dana Edelson, MD—Appointed to the COPD Taskforce of the
Society of Hospital Medicine
During the past year, Section of Hospital Medicine investigators:
• Found that the value of physician clinical judgment, as quantified
by the Patient Acuity Rating, when added to the Modified Early
Warning Score, improves its accuracy for predicting impending
clinical deterioration on medical wards (Churpek, Edelson, et al.,
JAMA Internal Medicine, 2015)
Professors
Evan Lyon, MD
Johnathan Erlich, MD +
Aelaf Worku, MD
(chief)
Shannon Martin, MD
Tina Gupta, MD
Charlie Wray, DO
Valerie Press, MD, MPH
Corey Henderson, MD+
Madhu Yarlagadda, MD
Robert Gibbons, PhD
Gregory Ruhnke, MD, MS, MPH
Michael Huber, MD+
Nancy Stewart, MD
Shalini Reddy, MD
Milda Saunders, MD, MPH
Christine Jun, MD
Michael Wilkinson, MD
Joyce Tang, MD
Jonathan Lio, MD
Anjan Tibrewala, MD
John Yoon, MD
Joan Miedema, MD
Christopher Boyle, MD
Mai Tuyet Pho, MD, MPH
Elizabeth Paesch, MD
A ssociate Professor
Jeanne Farnan, MD, MHPE
Brian Callender, MD
Anton Chivu, MD
Dana Edelson, MD, MS
Cheng-Kai Kao, MD
V. Ram Krishnamoorthi, MD
Grace Berry, MD+
Poushali Bhattacharjee, MD
Bryan Campbell, MD
Rebecca DeBoer, MD
Parin Desai, MD
Tien Dong, MD+
Micah Prochaska, MD
Sandeep Pulimi, MD
Dragana Radovanovic, MD
Tamara Pilot
Marc Robinson, MD+
Jonah Rubin, MD
+New FY 16 faculty
Anshu Verma, MD
33
significant work on the epidemiology of methicillin-resistant
Staph. aureus (MRSA) infections, and Dr. Ridgway is involved in
two anti-infective projects in collaboration with NorthShore
University HealthSystem.
Section of
INFECTIOUS
DISEASES &
GLOBAL HEALTH
Dr. David Pitrak
The Section of Infectious Diseases & Global Health is comprised of 12 full-time faculty
members who have a diverse scope of expertise, ranging from human immunodeficiency
virus (HIV), transplantation, surgical and oncologic infectious diseases to hospital epidemiology,
infection prevention, patient safety and global medicine. Under the direction of David Pitrak,
MD, the Section is recognized for providing outstanding clinical care, conducting impactful
research, and training the next generation of leaders in infectious diseases.
Section faculty are also recognized
for their expertise within the
institution and University of
Chicago Medicine (UCM). Of
note in FY 15, Emily Landon, MD,
hospital epidemiologist and
medical director for infection
control, established the UCM
Ebola Treatment Center, only
one of 39 such centers in
the U.S., three of which are
located in Chicago. The Center
accommodates patients who
are infected with or exposed to
Dr. Emily Landon
emerging contagious diseases
that pose a significant public health threat. Dr. Landon also
led an institutional hand hygiene initiative utilizing electronic
monitoring throughout the campus. Other Section faculty who
serve in significant clinical roles include Stephen Weber, MD,
as the chief medical officer and vice president for UCM. Jessica
Ridgway, MD, serves as associate hospital epidemiologist and
associate medical director for infection control. Jennifer Pisano,
MD, serves as director of the antibiotic stewardship program, and
Dr. Pitrak continues to chair the select-agent bio-safety committee.
The Section continues to provide outstanding consultative
services 24 hours a day, seven days a week, including serving the
oncology and transplant programs with the immunocompromised
host service and staffing the advanced practice infectious
diseases consult service to facilitate patient evaluation for
home antibiotic therapy prior to discharge. This service also
accommodated the increase in consults that has accompanied
higher clinical volumes for UCM since the opening of the Center
34
for Care and Discovery. The Section remains committed to
providing comprehensive HIV screening and care to HIV-infected
patients. The Chicago Center for HIV Elimination (John Schneider,
MD—director, Dr. Pitrak—co-director) continues its efforts to
eliminate new HIV transmissions on the South Side of Chicago.
The Center integrates programs for expanded HIV testing and
linkage to care, comprehensive HIV care and HIV prevention.
In FY 15, the Section has seen remarkable growth and productivity in
basic research and clinical trial activities. Particularly noteworthy
was Dr. Schneider’s success in obtaining three additional NIH R
series awards to advance current understandings of diffusion
of pre-exposure prophylaxis (PrEP) knowledge innovation, to
explore the feasibility and impact of a public health system
PrEP intervention in a recently emerging HIV epidemic in Athens
Greece, and to estimate the effectiveness of HIV prevention
and substance-abuse interventions for substance-using black
men who have sex with men. With additional funding from the
Chicago Department of Public Health, Dr. Pitrak’s expanded HIV
testing program continues to provide improved screening for
HIV, diagnosis at an early stage of disease and a high success rate
in aligning patients with an experienced HIV care provider. This
program has successfully resulted in the diagnosis of patients
at an earlier stage of disease and also reduced early AIDSrelated deaths within one year of diagnosis. Kathleen Mullane,
MD, continues to expand the clinical trial efforts in the Section
while maintaining her status as a top enroller nationally and
internationally in a number of infectious disease studies and as
a nationally recognized expert in Clostridium difficile infection.
Kenneth Pursell, MD, continues to participate in the solid organ
transplantation in HIV study, and has received additional funding
to study hypo-gammaglobulinemia and its clinical impact for the
entire multi-center cohort. Michael David, MD, is conducting
In the educational arena, the infectious diseases and global
health fellowship program continues to attract outstanding
fellows, the majority from the Department’s internal medicine
residency program. Within the Pritzker School of Medicine,
courses on global health and HIV infections have been
incorporated into medical school curriculum. The Wuhan
University Medical Education Reform Project (Renslow Sherer,
MD—director), received a new grant from Wuhan University
Medical School (WUMS) to provide technical assistance and
expert faculty support for reform of the WUMS medical school
curriculum and pedagogy, and for the WUMS internal medicine
residency training programs.
Dr. John Schneider
• Drs. Kathleen Mullane, David Pitrak, Kenneth Pursell and
Jean Luc Benoit, MD—Named Top Doctors® by Castle Connolly
• Provided new insights on new antimicrobial agents for C. difficile
and viral infections in immunocompromised hosts (Mullane,
et al., Antimicrobial Agents & Chemotherapy, 2015, and Chemaly,
• John Schneider, MD—Recipient of the Department of Medicine’s Mullane, et al., The New England Journal of Medicine, 2014)
2015 Diversity Award
• Provided a better understanding of the pathogenic role of
• Renslow Sherer, MD—Served as one of five international HIV
BK virus in stem cell transplant recipients and co-infection with
expert co-chairs for 2015 Guidelines for the Optimizing the
hepatitis B and C in HIV infection (Petty, Pursell, et al., Infectious
HIV Care Continuum: Evidence-Based Recommendations from
Disease Clinics of North America, 2014)
an IAPAC Panel
• Established a comprehensive anal care program with routine
During the past year, Section of Infectious Disease and
anal PAP smear screening and high-resolution anoscopy and
Global Health investigators:
biopsy to evaluate persons at risk for HPV-associated neoplasia
• Reported that expanded HIV testing and linkage to care on
(Schneider, et al., American Journal of Public Health, 2015)
the South Side of Chicago has resulted in diagnosing patients
Discovered that during the 2013-2014 influenza season, many
at an earlier stage of disease and decreased the number of early •
healthcare workers with influenza who received flu vaccine
deaths after HIV diagnosis between 2011 and 2013 (Pitrak, et al.,
were afebrile at presentation (Ridgway, Landon, et al., Clinical
Public Health Reports, 2015)
Infectious Disease, 2015)
• Examined the apoptosis pathways for T-cell death in HIV infection Found that sensitivity of surveillance testing may be a beneficial
•
and reported that thymus dysfunction, rather that chronic
component of an multi-drug resistant Gram-negative bacteria
inflammation, is the biggest barrier to immune recovery
infection control program in the ICU (Ridgway, et al., Journal of
(Pitrak, et al., AIDS Research and Human Retroviruses, 2014)
Microbiology, 2015)
• Demonstrated that the USA300 strain of MRSA spreads in
households and remains there for two to eight years (David, et
al., mBio, 2015)
Professors
Clinical A s s o c i a t e
David Pitrak, MD
(chief, co-director, Chicago
Center for HIV Elimination)
Jean Luc Benoit, MD
Michael David, MD, PhD
Nirav Shah, MD+
Kathleen Mullane, DO, PharmD
(director, clinical trials)
Kenneth Pursell, MD
(director, transplant
infectious diseases)
Renslow Sherer, MD
(director, Wuhan University
Medical Education Reform
program in China)
John Schneider, MD
(director, Chicago Center for
HIV Elimination)
Stephen Weber, MD, MS
(chief medical officer, UCM)
Emily Landon, MD
Section Administrator, Interim
(chief hospital epidemiologist,
medical director of the antibiotic Cindy Kitching
stewardship program)
Jennifer Pisano, MD
(associate director, antibiotic
stewardship program)
+New FY 16 Faculty
Mai Pho, MD, MPH+
Jessica Ridgway, MD
(associate hospital
epidemiologist)
35
for Medicare and Medicaid Services program. The nocturnal
dialysis program (Bharathi Reddy, MD—medical director) was
successfully established at the Kenwood Dialysis Unit in May 2015.
The renal transplant team (Michelle Josephson, MD—medical
director) continues to initiate community outreach functions
to identify transplant donors and recipients. Working alongside
Dr. Josephson is James Chon, MD (medical director, living
donor program ) who specializes in the evaluation of donors
and recipients for transplantation. In new initiatives, Dr. Kohn
started a new multidisciplinary program in conjunction with
radiology and developed a novel strategy to train renal fellows
in simulation centers utilizing a kidney biopsy simulation tool
with renal ultrasound.
Section of
NEPHROLOGY
Dr. Arlene Chapman
On March 31, 2015 the Department of Medicine welcomed Arlene Chapman, MD, Professor
of Medicine, as the new chief for the Section of Nephrology. For over 30 years, Dr. Chapman
has dedicated her professional career to improving the lives of patients with kidney disease,
focusing on clinical and translational research in hereditary kidney diseases as well as
providing excellence in patient care. She has devoted these efforts to the mentoring and
training of the future work force in the subspecialty of nephrology. Dr. Chapman succeeds F.
Gary Toback, MD, PhD, who served as interim chief since December 2008.
Dr. Chapman is a graduate of the McMaster School of Medicine.
She completed her internal medicine residency training and
nephrology fellowship training at Georgetown University School
of Medicine and her clinical research fellowship training in
nephrology at the University of Colorado School of Medicine.
She joined the University of Colorado faculty in 1988 and
remained there for ten years before being recruited to Emory
University, where she most recently served as Professor of
Medicine in the Renal Division and Co-Principal Investigator of
the Atlanta Clinical and Translational Science Institute.
Dr. Chapman’s research focuses on the mechanisms responsible
for cyst formation in autosomal dominant polycystic kidney disease
(ADPKD). With continuous NIH funding for the past 18 years, Dr.
Chapman has established the role of the renin-angiotensinaldosterone system in the development of hypertension in ADPKD,
the association between cyst burden, renal complications and
progression to renal failure in ADPKD and she has helped to
develop and establish imaging biomarkers that predict disease
progression, now approved for clinical trial enrichment by the
FDA. These accomplishments have led to the testing of promising
new agents in ADPKD, including vasopressin V2 receptor
antagonists as well as formally testing inhibition of the reninangiotensin-aldosterone system in ADPKD patients with
hypertension. Her early investigations also centered on the renal
and systemic hemodynamic changes that occur during normal
and pre-eclamptic pregnancies, and the genetic determinants
of antihypertensive drug responses and their side effects in
patients with essential hypertension.
• Arlene Chapman, MD—Recipient of the Polycystic Kidney Disease Research Foundation Lifetime Achievement Award. Dr. Chapman will also begin a five-year term for NIDDK
reviewing F32 grant submissions
• Fredric Coe, MD—Recipient of 2014 New York Academy of Medicine Edward N. Gibbs Memorial Award in Nephrology
• Elaine Worcester, MD—Appointed as president of the
ROCK Society and serves on the Nephrology Test Writing
Committee of the ABIM
• Jay Koyner, MD—Named co-director of the American Society Dr. Chapman’s academic contributions include membership on
several NIH study sections and membership on the Scientific
Advisory Council for the Polycystic Kidney Disease Foundation.
She has published nearly 170 peer-reviewed publications and
book chapters. Dr. Chapman is an active member of the American
Society of Nephrology, International Society of Nephrology and
the American Heart Association, and previously served on the
editorial boards for American Journal of Kidney Diseases, Kidney
International and the Journal of the American Society of Nephrology.
• Hatim Hassan, MD, PhD—Appointed as a member of
In other FY 15 news, the DaVita Outpatient Dialysis Centers
have proven to be an all-around success for the community and
patients since opening just a few years ago. Each of the dialysis
units, Kenwood Dialysis Unit, which houses two of the dialysis
programs—Chronic Hemodialysis (Bharathi Reddy, MD—medical
director) and the Home Dialysis/Chronic Peritoneal Dialysis
program (Orly Kohn, MD—medical director), the Woodlawn Unit
(Mary Hammes, MD—medical director) and the Stony Island Unit
(Nichole Stankus, MD—medical director ) received a four-star
rating from the Dialysis Facility Compare Star Ratings Center
of Nephrology’s Critical Care Nephrology annual review course and appointed to the editorial board of the Clinical Journal of the American Society of Nephrology
the Scientific Advisory Committee of the Oxalosis and Hyperoxaluria Foundation
• Tipu Puri, MD, PhD—Elected as the Scientific Advisory Board Chair of the National Kidney Foundation of Illinois and named as medical director for UCM’s Advanced Practice Service and executive medical director, inpatient operations
• Nicole Stankus, MD—Named to the CMS Technical Expert Panel regarding End Stage Renal Disease and the DFC Stars rating program.
• Anna Zisman, MD—Recipient of the Department of Medicine
• Bharathi Reddy, MD—Recipient of the Department of Medicine
Clinical Service Award for Procedure Activity
• Mary Hammes, MD—Recipient of the Department of Medicine
Clinical Service Award for Overall Clinical Activity
During the past year, Section of Nephrology investigators:
• Showed that kidney length predicts chronic kidney disease in autosomal dominant polycystic kidney disease using either ultrasound or magnetic resonance imaging (Chapman, et al., Kidney International, 2015)
• Found that acute kidney injury and mortality is common following ventricular assist device implantation (Koyner, et al., American Journal of Nephrology, 2014)
• Determined that women and men differ in the way they produce the hypercalciuria of idiopathic hypercalciuria (Worcester, Coe, et al., American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, 2015)
• Identified several factors that predict renal toxicity and its sequelae in patients undergoing chemoradiation for head and neck cancer. (Toback, et al., Anticancer Drugs, 2015)
• Found that leflunomide was well tolerated and successful in
preventing recurrence of viremia in renal transplant recipients with resistant cytomegalovirus infection (Chon, Josephson, et al., Case Reports in Nephrology & Dialysis, 2015)
Professors
Clinical A ssociate
Arlene Chapman, MD
(chief)
Mary Hammes, DO
Peili Chen, MD, PhD*
John Asplin, MD
Bryan Becker, MD
Orly Kohn, MD
W. James Chon, MD
Jay Koyner, MD
Patrick Cunningham, MD
Tipu Puri, MD, PhD
Hatim Hassan, MD, PhD
Nicole Stankus, MD
Benjamin Ko, MD
Fredric Coe, MD
Michelle Josephson, MD
Elaine Worcester, MD
36
In the educational realm, Section faculty continue to be
dedicated to training physicians for careers in clinical
nephrology and/or basic or clinical translational investigation.
The joint University of Chicago-NorthShore University
Nephrology Fellowship Program completed another successful
year with Nephrology fellows obtaining a unique community
hospital experience to complement the patient experience
gained at UCM. Within the Pritzker School of Medicine, Ben
Ko, MD, has been named co-director for the cell and organ
physiology course.
The Section is recognized for its diverse bench and patient
oriented investigations in acute kidney injury, epithelial cell
transport, growth and gene expression, and the pathophysiology
of kidney stone formation. New in FY 15 was a NIH R01 awarded
to Hatim Hassan, MD, PhD, to study oxalate transport and the
As a mentor, she has trained dozens of graduate students, medical
students, residents and nephrology fellows, and has worked with
the American Society of Nephrology on a number of education
and training committees.
Dr. Chapman’s vision for the Section of Nephrology is to build
upon its strong foundations in teaching and education, while
expanding the clinical and translational research portfolio and
enhancing the renal and transplant training programs.
metabolic pathways that mediate the formation of oxalatecontaining kidney stones . With Dr. Chapman’s arrival, the Section’s
grant portfolio added two U01 NIH awards: the Consortium for
Radiologic Imaging in Polycystic Kidney Disease and the Genetic
Modifiers in Polycystic Kidney Disease, as well as a large gift by
the Allen Foundation to evaluate the natural history of ADPKD in
adolescents and young adults.
Bharathi Reddy, MD
Section Administrator, Interim
Mark Mitchell
Anna Zisman, MD
37
Section of
PULMONARY/
CRITICAL CARE
MEDICINE
• Kyle Hogarth, MD—Recipient of the American College of
Chest Physicians Soffer Award for Editorial Excellence
During the past year, Section of Pulmonary/Critical Care Medicine
investigators:
• Michael Howell, MD—Served on several federal advisory
• Developed and validated a risk stratification tool for ward
committees including the Healthcare Infection Control
Practices Advisory Committee and the Ventilator-Associated
Event Surveillance Definition Working Group
• Edward Naureckas, MD—Served as the co-chair of the
Chronic Respiratory Therapies Committee in the Cystic
Fibrosis Foundation Guidelines Committee
Dr. Gökhan Mutlu
• Jason Poston, MD—Elected chair of the American Thoracic
Society’s Critical Care Core Curriculum and vice chair of the ATS Education Committee
• Julian Solway, MD—Named one of the leaders of the
Under the direction of Gökhan Mutlu, MD, the Section of Pulmonary/Critical Care Medicine
is recognized nationally for excellence in clinical medicine, impactful basic and translational
research, and innovative educational programs. The Section’s distinguished clinical programs
in critical care medicine, interstitial lung disease, cystic fibrosis and sleep medicine flourished
in FY 15.
In FY 15, two new faculty were welcomed to the Section: Remzi
Bag, MD, associate professor of medicine, is an experienced
and nationally recognized expert in lung transplant. As medical
director of the lung transplant program, Dr. Bag has already
made significant contributions to expand the program. Phil
Verhoef, MD, PhD, joined the Section as a Coggeshall Instructor,
focusing his research on the role of type 2 immunity in sepsis.
The interventional pulmonary program (Kyle Hogarth, MD, and
Tim Murgu, MD—co-directors) is recognized as an outstanding
program both locally and nationally. With steady growth since its
inception a few years ago, it has had significant clinical impact by
improving patient care through innovative procedures not
previously available which resulted increased outside referrals
and demand for services. The lung transplant program significantly
increased the number of patients who underwent transplantation,
nearly doubling transplants in FY 14 and FY 15 to mid-20s with a
goal of 30 transplants in FY 16. The COPD program (Steven White,
MD—director) also witnessed an increase in patients, visits
resulting in a huge impact on the readmission rates.
The Section maintains a successful research program and
secured additional funding during FY 15. Esra Tasali, MD, received
a new NIH R01 to study the effect of sleep extension on the risk
of developing metabolic syndrome. Julian Solway, MD, received
a highly competitive UH2 grant from the NHLBI for preclinical
development of myosolvins, a new class of medicine for asthma.
Dr. Mutlu was awarded a R21/R33 grant from NIEHS to study
the role of mitochondrial ROS in particulate matter-induced
epigenetic changes in macrophages. Robert Hamanaka, PhD, was
the recipient of a K01 award to study the role of mitochondrial
38
ROS in cell differentiation. Lastly, Dr. Verhoef successfully
obtained a K12 award to study omics, which will allow him to
incorporate transcriptomic analysis into his research on the role
of type 2 immunity in sepsis.
On the educational front, the Section continues to be very
active and faculty continue to distinguish themselves in all
domains of teaching and training. Under the directorship of Anne
Sperling, PhD, and co-directorship of Dr. Solway, the Section
successfully renewed the NIH T32 program in respiratory training
for an additional five years. The Section’s new Interventional
pulmonary fellowship program, one of only a few in the country,
recruited its first fellow who graduated in July. On July 1, 2015,
Jason Poston, MD, assumed the role of program director for the
PCCM fellowship program and Jay Balachandran, MD, began
serving as the program director for the sleep medicine fellowship.
development of an NIH/OD-funded initiative, myCHOICE
(Chicago Options-In-Careers Empowerment), to empower
trainees to select career directions in a more informed and
successful way
• Anna Birukova, MD—Appointed as a standing member of the
Veterans Administration Merit Award Scientific Review Group
• Konstantin Birukov, MD—Appointed as a standing member of the • Determined the best ideal strategy for the prevention of
ventilator-associated pneumonia (Howell, American Journal of
Respiratory and Critical Care Medicine, 2015)
• Found that REM sleep-related OSA increases the risk of
hypertension (Mokhlesi, American Journal of Respiratory and
Critical Care Medicine, 2014)
• Discovered that activation of beta-2 adrenergic receptors
further augment air pollution-induced IL-6 release and
thrombosis (Mutlu, Journal of Clinical Investigation, 2014)
• Identified thyroid disease as a predictor of survival in patients
with idiopathic pulmonary fibrosis (Noth, Strek, Chest, 2015)
• Discovered that downstream effectors of low molecular
• Matthew Churpek, MD, PhD—Recipient of the American Heart
• Demonstrated that early mobilization improves ICU-acquired
• Anne Sperling, PhD—Elected chair of the Program Committee
• Discovered that promyelocytic leukemia zinc finger plays
Association Young Investigator Award
for the Assembly on Asthma Inflammation and Immunology
for the American Thoracic Society
• John P. Kress, MD—Recipient of the Department of Medicine’s
weakness and glucose homeostasis (Kress, Hall, Chest, 2014)
a role in the development of innate lymphoid cells type 1
(Verhoef, The Proceedings of the National Academy of
Sciences of the USA, 2015)
• Holly Humphrey, MD, and Jason Poston, MD—Recipients of
the Pritzker School of Medicine’s Favorite Faculty Award
Professors
Robert Hamanaka, PhD*
Gökhan M. Mutlu, MD
(chief)
Remzi Bag, MD
(medical director, lung
transplantation program)
Kristen Knutson, PhD
Konstantin Birukov, MD, PhD
Patrick Singleton, PhD
Edward Garrity, Jr., MD
(associate vice chair for UHI, transplant
and EMR)
Jeffrey Glassroth, MD
(dean for clinical affairs)
John P. Kress, MD
Alan Leff, MD
Babak Mokhlesi, MD
(director, sleep fellowship program)
Edward Naureckas, MD
Imre Noth, MD
Anna Birukova, MD*
Bohao Chen, PhD*
Nickolai Dulin, PhD
Kyle Hogarth, MD
Michael Howell, MD, MPH
(associate chief medical officer for
clinical quality)
John McConville, MD
(vice chair for education and director,
internal medicine residency program)
Shwu Fan Ma, PhD *
Jason Poston, MD
Amy Guralnick, MD
Rekha Vij, MD
Coggeshall Instructors
Philip Verhoef, MD, PhD
Bhakti Patel, MD+
Elneda Boyd
Septimiu Murgu, MD
Anne Sperling, PhD
Esra Tasali, MD
Julian Solway, MD
(vice chair for research; associate dean
for translational medicine; and chairman, Jay Balachandran, MD
committee on molecular medicine)
Matthew Churpek, MD, PhD
Mary Strek, MD
Yun Fang, PhD
Steven White, MD
Kress, The New England Journal of Medicine, 2014)
weight hyaluronan may be useful in prevention of tumor
progression (Singleton, Journal of Biological Chemistry, 2014)
Holly Humphrey, MD
(dean for medical education)
Dr. Phil Verhoef
• Provided an excellent review on ICU-acquired weakness (Hall,
Committee on Conferences, American Physiological Society
Jesse Hall, MD
Dr. Remzi Bag
patients (Churpek, American Journal of Respiratory and Critical
Care Medicine, 2014)
+New FY 16 faculty
Robert Guzy, MD+
39
Section of
RHEUMATOLOGY
Dr. Marcus Clark
On the educational front, the Section is very active in multiple
training and teaching venues. Within the rheumatology
fellowship program, Anisha Dua, MD, was recently appointed
director, taking over from Dr. Curran. Under Dr. Curran’s
leadership, the Residency Review Committee for Internal
Medicine reviewed and continued accreditation of the
fellowship program effective 2/20/2015. Within the Pritzker
School of Medicine, Dr. Dua was also appointed as course
director for the MS4 clerkship in rheumatology.
Dr. Patrick Wilson
The Section of Rheumatology is comprised of a dynamic group of faculty who are committed
to providing outstanding state-of-the-art patient care, understanding the pathogenesis
of autoimmune diseases and training the next generation of physicians and scientists.
Under the leadership of Marcus Clark, MD, the Section of Rheumatology continues to make
remarkable advances in the knowledge of basic immunology that translate into new and
better treatments for those suffering from autoimmune and metabolic diseases.
In FY 15, Kichul Ko, MD, assistant
professor of medicine, joined
the faculty of the Section
of Rheumatology. Dr. Ko is
interested in the molecular
mechanisms behind systemic
lupus, especially in lupus
nephritis, and how they play a
role in clinical manifestations and
heterogeneity of the disease.
He is also interested in clinical
trials involving novel therapies
for lupus. Other noteworthy
faculty news in FY 15 includes the
Dr. Kichul Ko
promotions of Haochu Huang,
PhD, and Fotini Gounari, PhD, to associate professor, with Dr.
Gounari also achieving tenure status.
The Section maintains outstanding disease-focused clinical
programs that drive its reputation for excellence in the
treatment of rheumatic diseases. Of note is the very active
SLE program (Tammy Utset, MD, MPH—director), which is one
of the most recognized SLE clinics in the city of Chicago and
is recognized nationally as a clinical research and clinical trial
site. Through the efforts of James Curran, MD, the Inflammatory
Arthritis Clinic continues to expand and become more active
in clinical trials and gain prominence in the community. These
efforts have been enhanced by Reem Jan, MD, who is establishing
a joint ultrasound program within the Section. The gout program,
under the leadership of Michael Becker, MD, continues to be
nationally prominent.
40
With research funding over $6 M, the Section’s strong
investigative programs focus on innate and adaptive immunity
with a special emphasis on T- and B-cells, which are responsible
for autoimmunity. In FY 15, Section investigators were highly
successful in obtaining new federal NIH funding. Maria-Luisa
Alegre, MD, PhD, and Dr. Gounari were recipients of NIH R01
awards to investigate the impact of microbiota on alloimmune
responses in transplantation and to study how beta-catenin
contribute to tumor-prompting inflammation in colon cancer,
respectively. Dr. Clark was awarded a new R01 focused on the
transition between two B-cell
developmental mechanisms,
cell division and immunoglobulin
light chain recombination,
and successfully renewed his
NIH funded research project
to develop and apply novel
analytical tools to understand
how immune responses
are propagated within the
tubulointerstitium of human
lupus nephritis. In FY 15, Section
faculty continued to be
extremely productive, publishing
Dr. Fotini Gounari
results of their work in highimpact journals such as Science Translational Medicine, Nature
Immunology, Proceedings of the National Academy of Sciences, Nature
Communications, The Journal of Experimental Medicine, Cell, The
Journal of Clinical Investigation and Nature Reviews Immunology.
• James Curran, MD—Elected as
a Master in the American College of Rheumatology
• Maria-Luisa Alegre, MD, PhD—
• Identified mechanisms specifying recombination at Ig-kappa
(Mandal, Clark, et al., Nature Immunology, 2015)
• Conducted studies that emphasized the importance of
receiving the annual influenza vaccine for protection against
Named as co-chair of the current circulating human influenza strains and future strains
Community of Basic Scientists
with pandemic potential (Wilson, et al., Journal of Clinical
Leadership Track for the American Investigation, 2015)
Society of Transplantation
• Demonstrated tolerance memory in the context of infection
(Alegre, Chong, et al., Nature Communications, 2015)
• Kichul Ko, MD—Recipient of
the Department of Medicine’s
• Identified the NF-κB pathway as an important signaling axis
Best Abstract Award for
in T-cells, required for the elimination of growing tumors in
Translational Science
vivo. Maintaining or enhancing T-cell-NF-κB activity may be a
• Patrick Wilson, PhD—Served as promising avenue for anti-tumor immunotherapy (Alegre, et
organizer for the 2015 B-cell
al., Journal for ImmunoTherapy of Cancer, 2015)
Dr. James Curran
Keystone Meeting
• Demonstrated that naïve T-cells have basal nuclear levels of
During the past year, Section of Rheumatology investigators:
the transcription factor NF-κB, implying that anti inflammatory therapies targeting NF-κB may affect the pool
• Investigated the effects of Staphylococcus aureus infection
of naïve T-cells required to control infections (Molinero,
and provided insights on immune responses and potential
Alegre, et al., Proceedings of the National Academy of
vaccine development (Wilson, et al., Journal of Experimental
Sciences of the United States of America, 2014)
Medicine, 2014)
• Found that T-cell expression of IL10 is essential for tumor
• Found that RAG endonuclease binds to thousands of sites in
immune surveillance in the small intestine (Dennis, Gournari,
the lymphocyte genome (Teng, Mandal, Clark, et al., Cell, 2015)
et al., Cancer Immunology Research, 2015)
Professors
Clinical A ssociate
Marcus Clark, MD
(chief)
Fotini Gounari, PhD
Aimee Mayuga, MD
Maria-Luisa Alegre, MD, PhD
Patrick Wilson, PhD
Michael Becker, MD
(emeritus)
James Curran, MD
Leif Sorensen, MD, PhD
(emeritus)
Haochu Huang, PhD
Malay Mandal, PhD*
Anisha Dua, MD
(assistant director, fellowship program)
Kichul Ko, MD
Reem Jan, MD
Vladimir Liarski, MD
Ann Leu
+New FY 16 faculty
Kimberly Trotter, MD +
41
Select High-Impact
PUBLICATIONS
Department of Medicine faculty are extremely productive, publishing over 1,000 original
articles in a number of outstanding internal medicine and subspecialty journals. Below is a
sampling of some recent high-impact papers.
Annals of Internal Medicine
1. Czerwiec MK, Pincavage A, Arora VM. Annals
graphic medicine: Mr. S changes doctors.
Annals of Internal Medicine 162(11): W127-8, 2015.
2. Linas BP, Barter DM, Morgan JR, Pho MT, Leff
JA, Schackman BR, Horsburgh CR, Assoumou
SA, Salomon JA, Weinstein MC, Freedberg KA,
Kim AY. The cost-effectiveness of sofosbuvirbased regimens for treatment of hepatitis
C virus genotype 2 or 3 infection. Annals of
Internal Medicine 162(9): 619-29, 2015.
3. Graham KL, Wilker EH, Howell MD, Davis RB,
Marcantonio ER. Differences between early
and late readmissions among patients: a
cohort study. Annals of Internal Medicine 162(11):
741-9, 2015.
5. Eggener SE, Cifu AS, Nabhan C. Prostate
cancer screening. Journal of the American
Medical Association 314(8):825-6, 2015.
6. Altkorn D, Cifu AS. Screening for osteoporosis.
Journal of the American Medical Association
313(14): 1467-8, 2015.
7. Wray CM, Davis AM. Screening for hepatitis
C. Journal of the American Medical Association
313(18): 1855-6, 2015.
8. Pisano J, Cifu AS. Use of pneumococcal
vaccine in adults. Journal of the American
Medical Association 313(7): 719-20, 2015.
4. Moriates C, Shah N, Arora V. Primary nonadherence with prescribed medication. Annals
of Internal Medicine 161(9): 678, 2014.
9. Bird AN, Davis AM. Screening for abdominal
aortic aneurysm. Journal of the American
5. Balachandran JS, Patel SR. In the clinic:
obstructive sleep apnea. Annals of Internal
Medicine 161(9): ITC1-15, 2014.
10.Weyer GW, Davis AM. Screening for
asymptomatic carotid artery stenosis. Journal
of the American Medical Association 313(2):
192-3, 2015.
CA: A Cancer Journal for Clinicians
1. Daly B, Olopade OI. A perfect storm: how
tumor biology, genomics, and health care
delivery patterns collide to create a racial
survival disparity in breast cancer and
proposed interventions for change. CA: A
Cancer Journal for Clinicians 65(3): 221-38, 2015.
Cell
1. Teng G, Maman Y, Resch W, Kim M, Yamane A,
Qian J, Kieffer-Kwon KR, Mandal M, Ji Y, Meffre E,
Clark MR, Cowell LG, Casellas R, Schatz DG.
RAG represents a widespread threat to the
lymphocyte genome. Cell: 162 (4), 2015.
Journal of the American Medical
Association
1. Carmody D, Naylor RN, Philipson LH. Insulin
dosing in pediatric diabetic ketoacidosis:
where to start? Journal of the American Medical
Association 313(22): 2274-5, 2015.
2. Bakris GL, Pitt B, Weir MR, Freeman MW, Mayo
MR, Garza D, Stasiv Y, Zawadzki R, Berman L,
Bushinsky DA, AMETHYST-DN Investigators.
Effect of patiromer on serum potassium level
in patients with hyperkalemia and diabetic
kidney disease: the AMETHYST-DN randomized
clinical trial. Journal of the American Medical
Association: 314(2): 151-61, 2015.
3. Muir AJ, Poordad F, Lalezari J, Everson G,
Dore GJ, Herring R, Sheikh A, Kwo P, Hzode
C, Pockros PJ, Tran A, Yozviak J, Reau N, Ramji
A, Stuart K, Thompson AJ, Vierling J, Freilich
B, Cooper J, Ghesquiere W, Yang R, McPhee F,
Hughes EA, Swenson ES, Yin PD. Daclatasvir in
combination with asunaprevir and beclabuvir
for hepatitis C virus genotype 1 infection with
compensated cirrhosis. Journal of the American
42
4. Moss JD, Cifu AS. Management of
anticoagulation in patients with atrial
fibrillation. Journal of the American Medical
Association: 314(3):291-2, 2015.
11. Daly B, Olopade OI. Race, ethnicity, and the
diagnosis of breast cancer. Journal of the
American Medical Association 313(2): 141-2, 2015.
12.Cifu AS, Davis AM. Use of HPV vaccine in males
and females. Journal of the American Medical
Association 312(18): 1920-1, 2014.
13.Nabhan C, Rosen ST. Chronic lymphocytic
leukemia: a clinical review. Journal of the
American Medical Association 312(21): 2265-76,
2014.
14.Ducat LJ, Philipson LH, Anderson BJ. Routine
depression screening for patients with
diabetes—reply. Journal of the American Medical
Association 312(22): 2413, 2014.
15.Volerman A, Cifu AS. Cervical cancer
screening. Journal of the American Medical
Association 312(21): 2279-80, 2014.
16.Polonsky TS, Blumenthal RS, Greenland P.
Coronary artery calcium score. Journal of the
American Medical Association 312(8): 837-8, 2014.
17. Ducat L, Philipson LH, Anderson BJ. The mental
health comorbidities of diabetes. Journal of
the American Medical Association 312(7): 691-2,
2014.
18.Barach P, Arora VM. Hospital alarms and
patient safety. Journal of the American Medical
Association 312(6): 651, 2014.
19.Davis AM, Cifu AS. Lung cancer screening.
Journal of the American Medical Association
312(12): 1248-9, 2014.
Lancet
1. Zannad F, Cannon CP, Cushman WC, Bakris GL,
Menon V, Perez AT, Fleck PR, Mehta CR, Kupfer
S, Wilson C, Lam H, White WB, EXAMINE
Investigators. Heart failure and mortality
outcomes in patients with type 2 diabetes
taking alogliptin versus placebo in EXAMINE:
a multicentre, randomised, double-blind trial.
Lancet 385(9982): 2067-76, 2015.
Nature
1. Flach J, Bakker ST, Mohrin M, Conroy PC,
Pietras EM, Reynaud D, Alvarez S, Diolaiti
ME, Ugarte F, Forsberg EC, Le Beau MM,
Stohr BA, Mendez J, Morrison CG, Passegua
E. Replication stress is a potent driver of
functional decline in ageing haematopoietic
stem cells. Nature 512(7513): 198-202, 2014.
Nature Genetics
1. Zhang MY, Churpek JE, Keel SB, Walsh T, Lee MK,
Loeb KR, Gulsuner S, Pritchard CC, SanchezBonilla M, Delrow JJ, Basom RS, Forouhar M,
Gyurkocza B, Schwartz BS, Neistadt B, Marquez
R, Mariani CJ, Coats SA, Hofmann I, Lindsley
RC, Williams DA, Abkowitz JL, Horwitz MS, King
MC, Godley LA, Shimamura A. Germline ETV6
mutations in familial thrombocytopenia and
hematologic malignancy. Nature Genetics 47(2):
180, 2015.
2. Zhao Z, Chen CC, Rillahan CD, Shen R, Kitzing T,
McNerney ME, Diaz-Flores E, Zuber J, Shannon
K, Le Beau MM, Spector MS, Kogan SC, Lowe
SW. Cooperative loss of RAS feedback
regulation drives myeloid leukemogenesis.
Nature Genetics 47(5): 539-43, 2015.
3. Gamazon ER, Wheeler HE, Shah KP, Mozaffari
SV, Aquino-Michaels K, Carroll RJ, Eyler AE,
Denny JC, GTEx Consortium, Nicolae DL, Cox
NJ, Im HK. A gene-based association method
for mapping traits using reference transcriptome
data.Nature Genetics 47(9):1091-9=8, 2015.
Nature Reviews. Cancer
1. Hamamoto R, Saloura V, Nakamura Y.
Critical roles of non-histone protein lysine
methylation in human tumorigenesis. Nature
Reviews. Cancer 15(2): 110-24, 2015.
Proceedings from the National
Academy of Sciences USA
1. Tilburgs T, Crespo AC, van der Zwan A, Rybalov
B, Raj T, Stranger B, Gardner L, Moffett A,
Strominger JL. Human HLA-G+ extravillous
trophoblasts: Immune-activating cells that
interact with decidual leukocytes. Proceedings
of the National Academy of Sciences of the United
States of America 112(23): 7219-24, 2015.
2. Philipson LH, Bell G, Polonsky KS. Donald
F. Steiner MD; 1930-2014: Discoverer of
proinsulin. Proceedings of the National Academy
of Sciences of the United States of America 112(4):
940-1, 2015.
3. Ellebedy AH, Krammer F, Li GM, Miller MS,
Chiu C, Wrammert J, Chang CY, Davis CW,
McCausland M, Elbein R, Edupuganti S,
Spearman P, Andrews SF, Wilson PC, GarciaSastre A, Mulligan MJ, Mehta AK, Palese P,
Ahmed R. Induction of broadly cross-reactive
antibody responses to the influenza HA stem
region following H5N1 vaccination in humans.
Proceedings of the National Academy of Sciences of
the United States of America 111(34): 12276-7, 2014.
4. Ma L, Kim J, Hatzenpichler R, Karymov MA,
Hubert N, Hanan IM, Chang EB, Ismagilov
RF. Gene-targeted microfluidic cultivation
validated by isolation of a gut bacterium listed
in human microbiome project’s most wanted
taxa. Proceedings of the National Academy of
Sciences of the United States of America 111(27):
9768-73, 2014.
5. Stefka AT, Feehley T, Tripathi P, Qiu J, McCoy
K, Mazmanian SK, Tjota MY, Seo GY, Cao S,
Theriault BR, Antonopoulos DA, Zhou L, Chang
EB, Fu YX, Nagler CR. Commensal bacteria
protect against food allergen sensitization.
Proceedings of the National Academy of Sciences of
the United States of America 111(27): 9768-73, 2014.
6. Linderman SL, Chambers BS, Zost SJ,
Parkhouse K, Li Y, Herrmann C, Ellebedy AH,
Carter DM, Andrews SF, Zheng NY, Huang M,
Huang Y, Strauss D, Shaz BH, Hodinka RL, ReyesTeran G, Ross TM, Wilson PC, Ahmed R, Bloom
JD, Hensley SE. Potential antigenic explanation
for atypical H1N1 infections among middleaged adults during the 2013-2014 influenza
season. Proceedings of the National Academy of
Sciences of the United States of America 111(44):
15798-803, 2014.
Science
1. Heisler DB, Kudryashova E, Grinevich DO,
Suarez C, Winkelman JD, Birukov KG, Kotha
SR, Parinandi NL, Vavylonis D, Kovar DR,
Kudryashov DS. ACTIN-directed toxin. ACD
toxin-produced actin oligomers poison
formin-controlled actin polymerization.
Science: 349(62670:535-9, 2015.
3. Dalal SR, Chang EB. The microbial basis of
inflammatory bowel diseases. The Journal of
Clinical Investigation 124(10): 4190-6, 2014.
The Journal of Experimental Medicine
1. Pauli NT, Kim HK, Falugi F, Huang M, Dulac J,
Dunand CH, Zheng NY, Kaur K, Andrews SF,
Huang Y, DeDent A, Frank KM, Charnot-Katsikas
A, Schneewind O, Wilson PC. Staphylococcus
aureus infection induces protein A-mediated
immune evasion in humans. The Journal of
Experimental Medicine 211(12): 2331-9, 2014.
The New England Journal of Medicine
1. Brahmer J, Reckamp KL, Baas P, Crinò L,
Eberhardt WE, Poddubskaya E, Antonia S,
Pluzanski A, Vokes EE, Holgado E, Waterhouse
D, Ready N, Gainor J, Arén Frontera O, Havel
L, Steins M, Garassino MC, Aerts JG, Domine
M, Paz-Ares L, Reck M, Baudelet C, Harbison
CT, Lestini B, Spigel DR. Nivolumab versus
docetaxel in advanced squamous-cell nonsmall-cell lung cancer. The New England Journal
of Medicine 373(2): 123-35, 2015.
2. Francis PA, Regan MM, Fleming GF. Adjuvant
ovarian suppression in premenopausal breast
cancer. The New England Journal of Medicine
372(17): 1673, 2015.
3. Weir MR. Bakris GL. Pitt B. New agents for
hyperkalemia. The New England Journal of
Medicine 372(16): 1570-1, 2015.
4. Francis PA, Regan MM, Fleming GF, Láng I,
Ciruelos E, Bellet M, Bonnefoi HR, Climent
MA, Da Prada GA, Burstein HJ, Martino S,
Davidson NE, Geyer CE Jr, Walley BA, Coleman
R, Kerbrat P, Buchholz S, Ingle JN, Winer EP,
Rabaglio-Poretti M, Maibach R, Ruepp B,
Giobbie-Hurder A, Price KN, Colleoni M, Viale
G, Coates AS, Goldhirsch A, Gelber RD, SOFT
Investigators, International Breast Cancer
Study Group. Adjuvant ovarian suppression
in premenopausal breast cancer. The New
England Journal of Medicine 372(5): 436-46, 2015.
5. Baerlocher GM, Oppliger Leibundgut E,
Ottmann OG, Spitzer G, Odenike O, McDevitt
MA, Roth A, Daskalakis M, Burington B,
Stuart M, Snyder DS. Telomerase inhibitor
imetelstat in patients with essential
thrombocythemia. The New England Journal of
Medicine 373(10):920-8, 2015.
6. Weir MR, Bakris GL, Bushinsky DA, Mayo MR,
Garza D, Stasiv Y, Wittes J, Christ-Schmidt H,
Berman L, Pitt B, the OPAL-HK Investigators.
Patiromer in patients with kidney disease and
hyperkalemia receiving RAAS inhibitors. The New
7. Chin MH. How to achieve health equity. The New
8. Kwo PY, Mantry PS, Coakley E, Te HS, Vargas
HE, Brown R, Gordon F, Levitsky J, Terrault NA,
Burton JR, Xie W, Setze C, Badri P, Pilot-Matias
T, Vilchez RA, Forns X. An Interferon-free
antiviral regimen for HCV after liver
transplantation. The New England Journal of
Medicine 372(3): 211-21, 2014.
9. Bhatt DL, Bakris GL. Renal denervation for
resistant hypertension. The New England
Journal of Medicine 371(2): 184, 2014.
10.Kress JP, Hall JB. ICU-acquired weakness and
recovery from critical illness. The New England
Journal of Medicine 371(3): 287-8, 2014.
11. Shaw AT, Ou SH, Bang YJ, Camidge DR,
Solomon BJ, Salgia R, Riely GJ, Varella-Garcia
M, Shapiro GI, Costa DB, Doebele RC, Le
LP, Zheng Z, Tan W, Stephenson P, Shreeve
SM, Tye LM, Christensen JG, Wilner KD, Clark
JW, Iafrate AJ. Crizotinib in ROS1-rearranged
non-small-cell lung cancer. The New England
Journal of Medicine 371(21): 1963-71, 2014.
2. Ye CJ, Feng T, Kwon HK, Raj T, Wilson MT,
Asinovski N, McCabe C, Lee MH, Frohlich I, Paik
HI, Zaitlen N, Hacohen N, Stranger B, De Jager
P, Mathis D, Regev A, Benoist C. Intersection
of population variation and autoimmunity
genetics in human T cell activation. Science
345(6202): 1254665, 2014.
Science Translational Medicine
1. Matsuo Y, Park JH, Miyamoto T, Yamamoto
S, Hisada S, Alachkar H, Nakamura Y. TOPK
inhibitor induces complete tumor regression
in xenograft models of human cancer through
inhibition of cytokinesis. Science Translational
Medicine: 6(259): 259ra145, 2014.
The Journal of Clinical Investigation
1. Zhu X, Messer JS, Wang Y, Lin F, Cham CM,
Chang J, Billiar TR, Lotze MT, Boone DL,
Chang EB. Cytosolic HMGB1 controls the
cellular autophagy/apoptosis checkpoint
during inflammation. The Journal of Clinical
Investigation 125(3): 1098-110, 2015.
2. Henry Dunand CJ, Leon PE, Kaur K, Tan GS,
Zheng NY, Andrews S, Huang M, Qu X, Huang
Y, Salgado-Ferrer M, Ho IY, Taylor W, Hai R,
Wrammert J, Ahmed R, Garcia-Sastre A, Palese
P, Krammer F, Wilson PC. Preexisting human
antibodies neutralize recently emerged
H7N9 influenza strains. The Journal of Clinical
Investigation 125(3): 1255-68, 2015.
43
Medicine-Pediatrics Residents
Residents & Fellows:
PGY
LEVEL
CURRENT & GRADUATES
MEDICAL SCHOOL
2015 CHIEF RESIDENTS
Amber-Nicole Bird
Adam Mikolajczyk
Drexel University
Marc Robinson
Blair Wendlandt
Baylor University
University of Kansas
2016 CHIEF RESIDENTS
Justin Boike
Maureen Lyons
Patrick Lyons
Michelle Martinchek
University of Illinois
2015 THIRD YEAR RESIDENTS
Gray Akoegbe
Nikhil Bassi
Lane Benes
Eric Brandt
Christopher D'Angelo
Laura Dickens
Emily Escue
Demetra Gibson
Alex Gyftopoulos
Andrew Hantel
Jeffrey Jacobs
Michael Jelinek
Anita Kallepalli
Yasmin Karimi
Olufemi Kassim
Cathryn Lee
Matthew Modes
Jeremy O'Connor
Baldeep Pabla
Shawn Patel
Jacqueline Poston
Michael Putman
Malini Soundarrajan
Nathaniel Steiger
Cheryl Steiman
Matthew Stier
Aaron Tannenbaum
Eleanor Valenzi
Joseph Venturini
III
III
III
III
III
III
III
III
III
III
III
III
III
III
III
III
III
III
III
III
III
III
III
III
III
III
III
III
III
Meharry Medical College
Northwestern University
University of Wisconsin
Case Western Reserve University
Emory University
University of Tennessee
Tulane University
Loyola University
Rush Medical College
University of Texas Southwestern
University of Pennsylvania
Vanderbilt University
Emory University
University of Michigan
Indiana University
Boston University
Indiana University
Temple University
University of Alabama
Loyola University
2015 SECOND YEAR RESIDENTS
Vanessa Alonso
Emeka Anyanwu
Ankit Bhatia
Abdallah Bukari
Anisha Chandiramani
Nimit Desai
Amrish Deshmukh
Abdulrahman Dia
Danielle Farrington
Michelle Fletcher
Nathan Frogge
Shewit Giovanni
Nina Gupta
Xuan Han
Carmela Kiraly
David Kopelman
Michael Leukam
Nayna Lodhia
Erica MacKenzie
44
II
II
II
II
II
II
II
II
II
II
II
II
II
II
II
II
II
II
II
Loyola University
University of Minnesota
Emory University
Tufts University
Tufts University
Loyola University
Stanford University
2015 SECOND YEAR CONT’D.
MEDICAL SCHOOL
Mary Masters
Chandni Patel
Juan Reyes Genere
Sandra Shi
Justin Tomal
Dovie Watson
Benjamin Weber
Mia Weiss
Dawen Zhang
Linda Zhu
II
II
II
II
II
II
II
II
II
II
Washington University
Loyola University
Sackler School of Medicine
2015 FIRST YEAR RESIDENTS
Maria Bacalao
Mark Belkin
Margaret Boyle
Samantha Catlett
Kira Charney
Noa Cleveland
Michael Cui
Andre Davies
Lauren Feld
Sarah Gray
Greg Haman
Rebecca Harris
Blake Jones
Albert Lee
Linda Lee
Zachary Lonjers
Caileigh McKenna
Priya Mehta
Charles Muller
Julie Neborak
Jerry Nnanabu
Parita Patel
Steven Pearson
Gina Piscitello
Caitlyn Plonka
Natalie Reizine
Trisha Saha
Claire Shappell
Ethan Silverman
Danielle Stahlbaum
David Tehrani
Allison Thoburn
Eisha Wali
Hannah Wenger
I
I
I
I
I
I
I
I
I
I
I
I
I
I
I
I
I
I
I
I
I
I
I
I
I
I
I
I
I
I
I
I
I
I
Saint Louis University
Georgetown University
Michigan State University
Mount Sinai
Harvard University
Loyola University
University of California, San Francisco
Loyola University
Ohio State University
Brown University
University of Pittsburgh
Loyola University
Duke University
Wayne State University
University of California, Irvine
I
I
I
I
I
I
I
Indiana University
Chicago Medical School
PRELIMINARY
Stephanie Kim
Loren Kreuger
Peyton Pinkard
Chris Rishel
Kumar Sukhdeo
Nikki Sullivan
Lindsey Wold
PHYSICIAN SCIENTIST DEVELOPMENT PROGRAM
Joseph Wynne
Isabel Casimiro
Aadhavi Sridharan
Jonathan Trujillo
Dong Bo Yu
IV
IV
Virginia Commonwealth University
Niloufar Khan
Jennifer Seo
IV
IV
III
II
II
II
II
New York University
University of Washington
University of Iowa
Sofija Degesys
Vincent DiMaggio
Natalia Lipin
Ashley Thomas
III
III
III
III
Indiana University
SECOND YEAR RESIDENTS
Jessica Gold
Katie Good
Ellora Karmarkar
Amy Wang
II
II
II
II
Thomas Jefferson University
Virginia Commonwealth University
University of California, Los Angeles
I
I
I
I
University of Massachusetts
Dermatology Residents
PGY
LEVEL
MEDICAL SCHOOL
THIRD YEAR RESIDENTS
Alexander Means
Eduardo Moioli
IV
IV
Loyola University
Duri Yun
IV
III
III
III
Aga Khan Medical College, Pakistan
FIRST YEAR RESIDENTS
Laura Buford
Jingyun (Juliana) Gao
Ashley Jenkins
Rebecca Kaiser
III
Richard T. Benson II
III
University of Medicine and Dentistry of
New Jersey
Daniel Bickley
Stephen Tyler Constantine
Travis Cosban
Aoko Doris Crain
Jamila Goldsmith
Anand Gopalsami
Archit Gulati
Rwo-Wen Huang
James Y. Lindsey
Chali Mulenga
Gregory Podolej
Eric Shappell
Rickquel Tripp
Rukmini Velamati
III
III
III
III
III
III
III
III
III
III
III
III
III
III
Yeshiva University
Texas Tech University
Emory University
Tufts University
Baylor College of Medicine
Johns Hopkins University
Wake Forest University
Loyola University
University of Texas, San Antonio
II
II
II
II
Elyssa Berg
Andrew Bokarius
Colton Andrew Clay
Amy Faith Ho
Joffre Edward Johnson
Carrie Lynn Jurkiewicz
Paul Edward Kukulski
Ernest Nwachukwu, Jr.
Jennifer Ann Nykiel
Alejandro Palma
Nishma Azeem Sachedina
Yong Duk Suh
Eric Toone
Omar Ali Usman
Kenneth Alan Young
II
II
II
II
II
II
II
II
II
II
II
II
II
II
II
Yale University
Loyola University
Brown University
Columbia University
Columbia University
Loyola University
Carly Roman
Haider Bangash
Olga Radkevich-Brown
Kelvin Adjei-Twum
Zainab Abdul-Rahim
Rebecca Chohlas-Wood
Thomas Couri
Robert Sanchez
MEDICAL SCHOOL
Melissa Arredondo
Siddhartha Dante
PGY
LEVEL
PGY
LEVEL
MEDICAL SCHOOL
FOURTH YEAR RESIDENTS
Internal Medicine Residents
PGY
LEVEL
Emergency Medicine Residents
University of Oklahoma
Duke University
University of Missouri
Fellows
Sina Akhavan
Dillon Barron
Lauren Cooper
Michael Ernst
Steven Flynn
Racheal Gilmer
Omobolawa Kukoyi
Albert Leung
Andrew Marshall
Jacob Moore
Natalie Neumann
Archana Shah
Brian Sprouse
Shameeke Taylor
Joshua Wunder
Richard Zhang
I
I
I
I
I
I
I
I
I
I
I
I
I
I
I
I
University of North Carolina
University of Colorado
Duke University
Harvard University
University of Illinois at Chicago
Harvard University
PGY
LEVEL
MEDICAL SCHOOL
RESIDENCY
VI
VI
VI
VI
VI
VI
V
V
V
V
V
V
IV
IV
IV
IV
IV
IV
Dartmouth
University of Texas
University of Kentucky
University of Nebraska
Tufts University
Brigham and Women's Hospital
Brigham and Women's Hospital
Stanford University
New York University
Mayo Clinic
University of Nebraska
CARDIOLOGY
Cardiovascular Diseases
Andrew Beaser
Jonathan Grinstein
Sara Kalantari
Dave Pandya
Amita Singh
Bryan Smith
Isida Byku
Bow Young (Ben) Chung
Akhil Narang
Ann Nguyen
Adam Oesterle
Jonathan Rosenberg
Bhavna Balaney
Rohan Kalthiya
Kebed Kalie
Luke Laffin
Narang Nikhil
Jeremy Stone
45
Fellows cont’d.
PGY
LEVEL
MEDICAL SCHOOL
CARDIOLOGY
Interventional Cardiology Fellowship
Jeremy Estrada
VII
VII
VIII
Loyola University
University of Virginia
Rush University
VII
University of Buenos Aires, Argentina
Meir General Hospital, Israel
VIII
VII
University of Buenos Aires, Argentina
Meir General Hospital, Israel
VIII
Jefferson Medical College
Boston University
VII
Advanced Heart Failure
Diego Medvedofsky
Cardiac Imaging
Diego Medvedofsky
Anuj Mediratta
Cardiac Research
Corey Tabit
DERMATOLOGY
Kristen Paral
ENDOCRINOLOGY, DIABETES & METABOLISM
Medicine/Pediatrics
Katie O’Sullivan
Loyola University
University of California, San Diego
VI
V
V
IV
IV
7th October University
Medical College of Wisconsin
Oregon Health & Science University
University of Virginia
VI
VI
VI
IV
IV
Jagiellonian University Medical College, Poland
Universitatea de Medicnia Si Farmacie, Romaina
University of Miami
Baylor University
Loyola University
University of Medicine and Dentistry of New Jersey
Cleveland Clinic Children's Hospital
Pediatrics
Payal Patel
Magdalena Dumin
Carmen Mironovici
Michelle Lemelman
Susan Tucker
GASTROENTEROLOGY, HEPATOLOGY & NUTRITION
Keith Naylor
Britt Christensen
Ayal Hirsch
Christopher Chapman
Suraj Sharma
Shivi Siva
John Gaetano
Dejan Micic
Yutaka Tomizawa
Corlan Olukemi Adebajo
Emmanuel Coronel
Bilal Gondal
Vijaya Rao
Adam Mikolajczyk
Neha Nigam
Anna Lipowska
Mark Anthony Sofia
Thomas Lu
X
VIII
VIII
VII
VII
VII
VI
VI
VI
VI
V
V
V
V
IV
IV
IV
III
University of Melbourne
Israeli Institute of Technology
University of Toronto
Ross University
New York Medical College
Tokyo Medical College, Japan
Pennsylvania State University
University of Cuenca
Trinity College Dublin
Loyola University
Emory University
University of Cincinnati
St. Vincent's Hospital
BNAI Zion Medical Center
University of Toronto
Medical College of Pennsylvania
Mayo Clinic
University of Miami
Loyola University
Georgetown University Hospital
GENERAL INTERNAL MEDICINE
Elizabeth Tung
V
New York Medical College
Brown University
Ashley Haddad
IV
Louisana State University
GERIATRICS & PALLIATIVE MEDICINE
Jesse Soodalter (Palliative)
VII
Boston University
Boston University
Samir Bhalla (Geriatrics)
IV
Ross University
Wayne State University
Poonam Merai (Geriatrics)
IV
HEMATOLOGY/ONCOLOGY
46
Andrea Amico
VII
Indiana University
Indiana University
Robert Daly
VI
Harvard University
New York Presbyterian
RESIDENCY
Natalie Galanina
Kristen Pettit
Nanna Sulai
Randy Sweis
Hollis Walker
Shuang Qin Zhang
Jamie Brewer
Poornima Chennamaneni
Steven Maron
Sope Olugbile
Michael Tallarico
Kevin Wood
Jennifer Veneris
Christine Bestvina
Mikael Drazer
James Godfrey
Abiola Falilat Ibraheem
Kristen Tobin Vealey
Allison West
Kristen Whitaker
VI
VI
VI
VI
VI
VI
V
V
V
V
V
V
IV
IV
IV
IV
IV
IV
IV
IV
Wake Forest University
Loyola University
Jefferson Medical College
University of Lagos
University of Kansas
Morehouse School of Medicine
Pennsylvania State University
New York University
Drexel University
Yale University
Mayo Clinic
Yale University
Yale University
Loyola University
New York Presbyterian
Duke University
Obafemi Awolowo College of Health Sciences, Nigeria
Loyola University
George Washington University
HOSPITAL MEDICINE/HOSPITALIST SCHOLARS
VI
Adult
Milad Abusag
Anila Bindal
Disha Kumar
Mizuho Mimoto
Rajesh Jain
MEDICAL SCHOOL
HEMATOLOGY/ONCOLOGY CONT’D.
Clinical Cardiac Electrophysiology
John Green
Zaid Aziz
PGY
LEVEL
RESIDENCY
Poushali Bhattacharjee
Rebecca DeBoer
Jonathan Erlich
Tina Gupta
Michael Huber
Jonathon Lio
Micah Prochaska
Charlie Wray
Mai Pho
Kiran Raj Pandey
Marc Robinson
Aelef Worku
University of Texas
Loma Linda University
Wright State University
Western University
Nepal Medical College, Kathmandu University, Nepal
Baylor University
Mount Sinai
Boston University
University of Maryland
Loma Linda University
Yale University
Rosalind Franklin University
Mount Sinai
INFECTIOUS DISEASES & GLOBAL HEALTH
Mary Ellen Acree
Lindsay Petty
Jennifer Steinbeck
Moira McNulty
Leona Ebara
Daniela Pellegrini
VII
VII
VI
V
IV
IV
Loyola University
Kobe University
Loyola University
University of New Mexico
VI
V
V
V
V
V
IV
IV
IV
Kasturba Medical College, Manipal, India
Aga Khan Medical College, Pakistan
Chicago College of Osteopathic Medicine
Sawai Man Singh Medical College, India
Université Saint-Joseph Faculté de Médecine, Lebanon
Gandhi Medical College, Bhongir, India
Topiwala National Medical College, Bombay, India
Seton Hall University
Advocate Christ / UIC
William Beaumont Hospital
University of Chicago-NorthShore University HealthSystem
St. Francis Hospital, Evanston, IL
George Washington University
Advocate Illinois Masonic Medical Center
Cleveland Clinic
NEPHROLOGY
Ling-Xin Chen
Gaurav Alreja
Kristie Delaney
Mohammad Puri
Ankit Rawal
Aparna Sharma
Omar Al Dhaybu
Vamshi Bende
Vipuj Shah
PULMONARY/CRITICAL CARE MEDICINE
Catherine Bonham
Justin Oldham
Tina Shah
Ayodeji Adegunsoye
Joshua Mason
Krysta Wolfe
David Wu
Karen Dugan
Heng Duong
William Parker
Juan Rogas
Nathan Schoettler
Leah Witt
VIII
VIII
VII
VI
VI
V
V
IV
IV
IV
IV
IV
IV
University of Ibadan, Nigeria
Ross University
University of Illinois at Chicago
University of California, Davis
Drexel University
State University of New York
VII
VII
VII
VI
University of Jordan
St. George's University
Ain Shams University
University of Arizona
Drexel University
Columbia Presbyterian Medical Center
Good Samaritan Hospital
SLEEP MEDICINE
Mohammed Alzoubaidi
George Nguyen
Jessica Cooksey
Mostafa Shalaby
47
Fellows cont’d.
PGY
LEVEL
Graduating Fellows
CURRENT POSITION
MEDICAL SCHOOL
EMERGENCY MEDICINE CONT’D.
INTERVENTIONAL PULMONOLOGY
Balaji Laxmanan
VII
V
IV
IV
University of Texas
Shri Vasantrao Naik Govt. Medical College Midwestern University, Chicago College of Osteopathic Medicine
University of Illinois University of Illinois RHEUMATOLOGY
Mariam Siddiqui
Heena Birbal Jain
Ahmad Salah
RESIDENCY AND FELLOWSHIP PROGRAM GRADUATES
Graduating Residents
CURRENT POSITION
INSTITUTION
Chief Resident
Chief Resident
Chief Resident
Cardiology Fellow
Neurology Resident
Hospitalist - Gastroenterology
Hematology/Oncology Fellow
Pulmonary/Critical Care Fellow
Hospitalist
Hospitalist Scholar
Primary Care Physician
Radiation Oncology Resident
Gastroenterology Fellow
Hospitalist
Hospitalist Scholar
Endocrinology Fellow
Chief Resident
Chief Resident
Cardiology Fellow
Cardiology Fellow
Chief Resident
Chief Resident
Gastroenterology/Liver Fellow
Endocrinology Fellow
Cardiology Fellow
Dermatology Resident
Global Health Scholar
Allergy and Infectious Disease Fellow
Chief Resident
Dermatology Resident
Cardiology Fellow
Hospitalist - Nephrology
Neurology Resident
MacNeal Hospital
Illinois Masonic Hospital
Centegra Health System
University of Texas
St. Louis University
Mercy Hospital
National Cancer Institute
University of North Carolina
Cleveland Clinic
University of South Carolina
Los Angeles, California
Micrographic Surgery and Dermatologic Oncology (Mohs) Fellow
Clinical Educator
Micrographic Surgery and Dermatologic Oncology (Mohs) Fellow
Pediatric Dermatology Fellow
University of Iowa
NorthShore University HealthSystem
Cooper University Hospital
INTERNAL MEDICINE
Jason Alexander
Amber-Nicole Bird
Justin Boike
Ellis Christian
Scott DeBoer
Tien Dong
Michael Drazer
Karen Dugan
Bryan Eberle
Jonathan Erlich
Lindsay Esch
Penny Fang
Margarita German
Cory Henderson
Michael Huber
Rajesh Jain
Kyle Karches
William Karkowsky
Benjamin Kenigsberg
Andrew Levy
Kathryn Lurain
Patrick Lyons
Michelle Martinchek
Adam Mikolajczyk
Miz Mimoto
Nikhil Narang
Meredith Orseth
William Parker
Marc Robinson
Mark Sofia
Anita Turk
Xiao Wan
Blair Wendlandt
Nichole Welch
Allison West
Maureen Wilcox
Calvin Williams
Aaron Wolfson
Jin Hyung Yoo
Changrui Xiao
DERMATOLOGY
Sogyong Auh
Mara Beveridge
Min Deng
Adena Rosenblatt
DERMATOLOGY PATHOLOGY
Adaobi Nwaneshiudu
Assistant Professor of Dermatology
Temple University
Attending Physician
Attending/Staff Physician
Simulation Fellow & Clinical Instructor
Clinical Informatics Fellow
Attending EM Physician
Attending Physician
Simulation Fellow
Attending Physician
Emergency Physician
Administrative Fellow
Locums Tenens - Nationwide
Cook County Hospital & Rush University Health System
Stanford University
St. Peter's Hospital in Helena, MT
Presence St. Joseph Medical Center
Stanford University
Locums Tenens
U.S. Air Force
Tampa General Hospital
EMERGENCY MEDICINE
Rosalyn Chi
Katon Floyd
Sara Hock
Yaniv Kerem
Tiffany Kniepkamp
Richard Louissaint
Larry Mo
Gillian Munitz
Sohil Patel
Reginald Saint-Hilaire
48
INSTITUTION
RESIDENCY
Sangeeta Sakaria
Benjamin Savitch
Mohammad Subeh
Ernest Sutton, Jr.
Jason Turner
Attending Physician
Attending Physician
Fellow & Clinical Instructor
Attending Physician
Attending EM Physician
University of Chicago & Mt. Sinai Hospital
Presence St. Joseph Medical Center
University of California- Irvine
Medical City in Dallas, TX
Delray Medical Center in Delray Beach, FL
Private Practice
Advanced Fellow Interventional Cardiology
Clinical Lecturer
Advanced Fellow Interventional Cardiology
Advanced Fellow Electrophysiology
Advanced Cardiac Imaging
Assistant Professor, Electrophysiology
Interventional Cardiologist
Advanced Cardiology Research
Los Angeles, California
Centegra Hospital - McHenry
CARDIOLOGY
Liying Cai
Jose Chavez
Ryan Cunnane
Jeremy Raider Estrada
John Green
Anuj Mediratta
Olusegun Oyenuga Elizabeth Retzer
Corey Tabit
ENDOCRINOLOGY, DIABETES & METABOLISM
Meltem Zeytinoglu
Assistant Professor of Medicine
GASTROENTEROLOGY, HEPATOLOGY & NUTRITION
Mariano Gonzalez-Haba Ruiz
Andres Yarur
Sujit Janardhan
Gabriel Lang
Jami Kinnucan
Jennifer Newton
Ajaypal Singh
Anouar Teriaky
Staff Physician
Assistant Professor
Assistant Professor
Interventional GI Fellow
Clinical Lecturer
Transplant Hepatology Fellow
Advanced Endoscopy Fellow
GI/Hepatology Staff Physician
Hospital Universitario Puerta de Hierro, Madrid
Medical College of Wisconsin in Milwaukee
Rush University Medical Center
Washington University in St. Louis
Scarborough Hospital, Toronto
GERIATRICS & PALLIATIVE MEDICINE
Rachel Norris
Heather Costello
Angela Beckert
Emma Daisy
Mark Watson
Attending Physician
Attending Physician
Clinical Instructor
Private Practice
Attending Physician
Season's Hospice
HEMATOLOGY/ONCOLOGY
Seleha Sajid
Erica Stringer
Apoorva Chawla
Emily Curran
Jesse Soodalter
Stephanie Tsai
Gottfried von Keudell
Assistant Professor
Assistant Professor
Staff Physician
Clinical Pharmacology Fellow
Palliative Medicine Fellow
Assistant Professor
Assistant Professor
Baylor University
Northwest Oncology & Hematology
Loyola University
Yale University
HOSPITAL MEDICINE/HOSPITALIST SCHOLARS
Nancy Stewart
Creighton University
INFECTIOUS DISEASES & GLOBAL HEALTH
Nirav Shah
Jennifer dela Cruz
Clinical Associate
Physician
Northwestern Memorial Group - Central Dupage Hospital
Private Practice
Private Practice
Private Practice
NEPHROLOGY
Jaime Sua Baylock
Vikash Sinha
Chang Xu
Talal Khairi
PULMONARY/CRITICAL CARE
Jared Greenberg
Bhakti Patel
Balaji Laxmanan
Jessica Cooksey
Assistant Professor
Interventional Pulmonology Fellow
Sleep Fellow
Rush University
49
Graduating Fellows
CURRENT POSITION
INSTITUTION
Academic Faculty
Academic Faculty
Private Practice
Great Lakes Naval Base
NorthShore University Health System
Chest Diseases Associates and Sleep Disorders Center,
Merrillville, IN
SLEEP MEDICINE
George Gettys
Camelia Musleh
Bilal Safadi
INTERVENTIONAL PULMONOLOGY
Katarine Egressy
Director, Pulmonary Oncology/Interventional Pulmonology
Rocky Mountain Heart and Lung Center
Private Practice
Stanford University
RHEUMATOLOGY
Kichul Ko
Yashaar Chaichian
Kimberly Trotter
Nandita Gatla
Niharika Sharma
50
51
2015 Total Sponsored RESEARCH
2015 Total Sponsored
AWARDS
RESEARCH AWARDS
SEC TION OF CARDIOLOGY
SPONSORED RESE ARCH
Public Health Service
P R I N C I PA L
I N V E S T I G AT O R
TITLE OF FUNDED GR ANT
ANNUAL DIREC T
COSTS
ANNUAL INDIREC T
COSTS
SEC TION OF CARDIOLOGY — Public Health Ser vice
Integrin-Triggered Signaling and Macrophage Mode Switching in Atherosclerosis
Hofmann-Bowman, Marion
Pro-inflammatory S100 Protein as Disease Modifier in Calcific Aortic Valve Disease
Gomberg-Maitland, Mardi
Right Ventricular Pulmonary Vascular Interactions in Pulmonary Hypertension (Subcontract with the
University of Wisconsin)
Kim, Gene
MicroRNAs in Cardiac Development
$115,000
$9,200
Liao,James
ROCK and Obesity
$178,200
$103,356
$212,231
$123,094
McNally, Elizabeth
$8,923
$142,100
$7,276
$4,220
$449,297
$33,511
Lipoproteins Effect on G Protein Function
$245,000
$142,100
Project 2: Failed Regeneration in the Muscular Dystrophies: Inflammation, Fibrosis and
Fat (Subcontract with University of Pennsylvania)
Core A: Failed Regeneration in the Muscular Dystrophies: Inflammation, Fibrosis and Fat (Subcontract
with University of Pennsylvania)
Ozcan, Cevher
$111,535
$245,000
Cardiovascular Sciences Training Grant
Myoferlin in Muscle Membrane Fusion and Repair
$9,360
$5,429
$179,417
$95,098
$4,275
$2,394
Regulating Fibrosis and Muscle Growth in the Muscular Dystrophies.
$54,389
$31,546
Preclinical Testing of a Novel Method to Block TGFbeta Family Proteins in DMD (Department
of Defense)
$146,476
$84,956
Mitochondrial Mechanisms and Novel Therapeutic Targets in Atrial Fibrillation
Total PHS Research
Industry Grants
T O TA L
Alenghat, Francis
Novel Signaling Pathways in Ischemic Stroke
State/Association/Foundations
$141,775
$11,342
$2,099,231
$797,269
F Y 10
F Y 11
F Y 12
F Y 13
F Y 14
F Y 15
$5,300,507
$4,918,576
$5,116,924
$4,191,962
$5,095,494
$2,896,500
$1,414,863
$1,284,666
$1,317,504
$831,732
$463,932
$613,449
$856,273
$779,016
$1,165,945
$1,614,635
$885,107
$1,356,465
$7,571,643
$6,982,258
$7,600,373
$6,638,329
$6,444,533
$4,866,414
S E C T I O N O F C A R D I O L O G Y — S t a t e /A s s o c i a t i o n / F o u nd a t i o n G r a n t s
Blair, John
Microvascular Dysfunction in Heart Failure with Preserved Ejection Fraction (American Heart Association)
$70,000
$7,000
Liao, James
ROCK and Endothelial Function (American Heart Association)
$56,036
$0
Lowry, Elinar
The Experience of Children Undergoing 131I-Metaiodobenzylguanidine Therapy and the Parents and
Nurses Who Care for Them: A Qualitative Descriptive Study (The Daisy Foundation)
$4,360
$0
McNally, Elizabeth
Testing Exon Skipping (Kurt + Peter Foundation)
$173,777
$0
Assessing the Assembly of y-Sarcoglycan Missing Exons 4 through 7 in LGMD 2C (Kurt + Peter Foundation)
$60,000
$0
Mor-Avi, Victor
Echocardiographic Evaluation of Hemodynamic Significance of Coronary Stenosis in Patients with
Chest Pain Undergoing CT Angiography (American Society of Echocardiography)
$90,909
$9,091
Nathan, Sandeep
Interventional Cardiology and Vascular Medicine Fellowship Program (Abbott Fund)
$33,099
$3,677
Polonsky, Tamar
Effect of Hospital Admission for Acute Myocardial Infarction and Stroke in New York after
Implementation of Trans Fat Bans (Seed Grant)
$2,500
$0
Vo, Andy
Modifiers of Cardiorespiratory Function in Muscular Dystrophy (American Heart Association)
$26,000
$0
Wu, Rongxue
Functional Characterization of ARNT/HIF1beta (American Heart Association)
$70,000
$7,000
$586,681
$26,768
Total State/Association/Foundation Grants
SEC TION OF C ARDIOLOGY — Industr y Gr ant s
Burke, Martin
S-ICD PAS SYSTEM POST APPROVAL STUDY (S-ICD PAS)(Boston Scientific)
$86,836
$21,709
Gomberg-Maitland, Mardi
IN-US-259-0129: A Phase I Study of Ranolazine Acute Administration and Short Term Administration in
Pulmonary Hypertension (Gilead)
$50,544
$12,636
DelIVery for Pulmonary Arterial Hypertension (PAH)(Medtronic)
$208,970
$52,243
Adult Electrophysiology Fellowship Program (Medtronic)
$30,000
$0
Cardiac Electrophysiology Fellowship (Boston Scientific)
$26,500
$0
Shah, Atman
TP-6364: AVERT TRIAL (Osprey Med)
$50,843
$12,711
Uriel, Nir
RAMP: Study for Evaluation and Speed Adjustment of LVAD Patients (Heartware)
Nayak, Hemal
Combined Clinical Trials (47) with Earnings Less Than $50K
Total Industry Grants
50
Depar tment of Medicine
$73,840
$18,460
$569,044
$142,129
$1,096,577
$259,888
51
P R I N C I PA L
AWARDS
ANNUAL DIREC T
COSTS
ANNUAL INDIREC T
COSTS
Mechanisms of UVA-Induced Skin Cancer
$233,913
$130,991
Autophagy and GG-NER in UVB-Induced Skin Cancer
$225,000
$130,500
Lang, Deborah
$4,082
$2,367
$462,995
$263,858
Regulation of the Vertebrate Melanocyte Lineage by the AP2 Transcription Factor Family (Subcontract
with the University of Iowa)
S E C T I O N O F D E R M AT O L O G Y — S t a t e /A s s o c i a t i o n / F o u nd a t i o n G r a n t s
Bolotin, Diana
Long-Term Efficacy of Nd:YAG Laser in the Treatment of Hidradenitis Suppurativa (Chicago
Dermatological Society)
He, Yu-Ying
Molecular Mechanisms of Skin Carcinogenesis in Organ Transplant Recipients (American Cancer
Society)
Lang, Deborah
The Role of PAX3 in Melanoma Metastasis (American Cancer Society)
Shea, Christopher
Predictive Value of Early Biopsies of Atypical Nevi in Melanoma Surveillance (Chicago Dermatological
Society)
$4,000
$0
$150,000
$30,000
$104,167
$20,833
$1,850
$0
$260,017
$50,833
S E C T I O N O F D E R M AT O L O G Y
F Y 10
F Y 11
F Y 12
$472,552
$913,036
$839,767
$154,737
$0
$159,500
$4,778
$0
$0
$632,067
$913,036
$999,267
Industry Grants
T O TA L
P R I N C I PA L
F Y 13
F Y 14
F Y 15
$701,097
$665,474
$726,853
$339,500
$310,850
$310,850
$0
$0
$0
$1,040,597
$976,324
$1,037,703
ANNUAL DIREC T
COSTS
ANNUAL INDIREC T
COSTS
SEC TION OF EMERGENCY MEDICINE — Public Health Ser vice
Prabhakar, Nanduri
Brady, Matthew
Ehrmann, David
Integrative Consequences of Hypoxia
Hypothermia in Cardiac Arrest: Akt Preservation of Mitochondrial Integrity
Total PHS Research
Hogan, Teresita
Emergency Department Management of Pain in Older Adults (The Mayday Fund)
$1,411,552
$595,186
$1,450,108
$213,554
$117,252
$9,380
$2,978,912
$818,120
Padela, Aasim
Developing a Tailored Mammography Intervention for American Muslims (American Cancer Society)
$134,954
$10,796
$67,420
$10,113
The Concept and Application of Darurah in Medicine: Findings from a National Survey of Muslim
Physicians (Institute of Islamic Thought)
$3,000
$0
Islamic Bioethics Symposium (Doha Intl Center for Interfaith Dialogue/Bayan Claremont)
$8,399
$0
$307,148
$20,909
Scientific Discoveries & Theological Realities-Exploring the Intersection of Islam and Medical Science
(John Templeton Foundation)
SEC TION OF EMERGENC Y MEDICINE — Industr y Gr ant s
Tanzania Emergency Medicine Partnership (Abbott Fund)
Prabhakar, Nanduri
Carotid Body Neural Signal as Potential Therapeutic Target (GlaxoSmith Kline)
$40,000
$0
$72,981
$29,192
$112,981
$29,192
52
F Y 10
F Y 11
F Y 12
F Y 13
F Y 14
F Y 15
$4,904,491
$3,661,625
$3,500,687
$3,196,160
$2,454,944
$3,797,032
$96,661
$25,000
$85,876
$91,092
$157,477
$328,057
Industry Grants
$68,890
$40,186
$60,000
$40,000
$182,173
$142,173
$5,070,042
$3,726,811
$3,646,563
$3,327,252
$2,794,594
$4,267,262
$447,008
$115,209
$64,517
$7,558
$605
$30,265
$17,554
Circadian Genes and Adipose Function: Impact of Chronotype, Obesity and Race
$302,260
$148,764
Meal time effects on metabolic health (Subcontract with Brigham and Women’s)
$21,750
$12,615
B-cell Function and Cognition in the Restoring Insulin Secretion (RISE) Study (Subcontract with
Wake Forest University)
$33,290
$19,308
Sleep, Aging, and Circadian Rhythm Disorders (Subcontract with Harvard University)
Diabetes Prevention Program Outcomes Study Phase 2
$284,871
$165,117
Enhancement of beta Cell Function with Pharmacologic and Sleep Apnea Treatment-Multi-PI
$609,823
$281,116
DPPOS Follow-up
$228,330
$132,266
$17,565
$30,285
Greeley,Siri
Incretin Regulation of Insulin Secretion in Human Neonatal Diabetes
$156,150
$12,123
KCNJ11 Diabetes: Exploring the Role of KATP Channels in the Brain
$50,000
$24,360
Hara, Manami
Quantitative Analysis of Aging in the Human Pancreas
$47,250
$27,405
Littlejohn, Elizabeth
Fault-Tolerant Control Systems for Artificial Pancreas (Subcontract with Illinois Institute of Technology)
$47,250
$27,405
Control System for Artificial Pancrease Use During and After Exercise (Subcontract with Illinois
Institute of Technology)
$59,918
$27,940
Molecular Physiology of Store-Dependent Ca2+Entry in Pancreatic Beta Cells (Subcontract with
Suny Upstate Medical University)
$155,030
$89,917
Chicagoland Diabetes TrialNet Clinical Center
$256,392
$115,300
Philipson, Louis
Refetoff, Samuel
Sargis, Robert
Van Cauter, Eve
Pediatric Endocrinology Research Training
$115,956
$9,276
Integrated Clinical and Basic Endocrinology Research
$202,726
$16,218
Thyroid Physiology Studies of Inherited Disorders.
$365,970
$204,943
$80,350
$8,035
Metabolic Control of Proinsulin Biosynthesis Translation
$207,653
$116,286
Environmental Endocrine Disruption of Adipocyte Metabolism
$148,294
$11,864
Metabolic Impact of Fetal or Adult Exposure to Environmental Endocrine Disruptors
$148,500
$86,130
Brehmn Coalition:De-differentiation During Progression of beta Cell Loss in type 1 diabetes
(Subcontract with University of Michigan)
Alterations of Sleep and Circadian Timing in Aging
Wicksteed, Barton
Modulation of Beta-Cell PKA Activity Affects Glucose Homeostasis
Total PHS Research
$55,845
$8,700
$431,692
$241,076
$52,530
$4,202
$205,425
$115,038
$5,221,276
$2,452,653
S E C T I O N O F E N D O C R I N O L O G Y, D I A B E T E S & M E TA B O L I S M — S t a t e /A s s o c i a t i o n / F o u nd a t i o n G r a n t s
Cohen, Ronald
Role of SMRT in the Adipocyte (American Diabetes Association)
$90,000
Greeley, Siri
nPOD Coordinating Center (Juvenile Diabetes Research Foundation)
$45,454
$4,545
Littlejohn, Elizabeth
Fault Detection, Diagnosis and Recovery for Risk Mitigation in AP Systems (Juvenile Diabetes Research
Foundation/IIT)
$42,639
$4,264
Naylor, Rochelle
Increasing Provider Knowledge of Maturity-Onset Diabetes of the Young(MODY) at the University of
Chicago (Goldenburg Foundation)
$2,500
$0
Increasing Diagnosis of Maturity-Onset Diabetes of the Young (MODY) in Racial Minorities
(Goldenberg Foundation)
$5,000
$0
Biomarkers of Functional Beta Cells (Juvenile Diabetes Research Foundation)
$46,513
$4,651
Human Genetics and Molecular Biology (Hariri Foundation)
$55,000
Philipson, Louis
SEC TION OF EMERGENCY MEDICINE
T O TA L
$770,704
Identification and Replication of Type 2 Diabetes Genes in Mexican Americans (Subcontract with
University of Texas)
Training Grant in Circadian and Sleep Research (Subcontract with Northwestern University)
$0
Checkett, Keegan
Diabetes Research and Training Center
Cardiometabolic Risk of Shift Work: Sleep Loss vs. Circadian Disruption
$93,375
SPONSORED RESE ARCH
ANNUAL INDIREC T
COSTS
Contribution of Increased VDR and CaR to Hypercalciuria in the GHS Rat (Subcontract with the
University of Rochester)
S E C T I O N O F E M E R G E N C Y M E D I C I N E — S t a t e /A s s o c i a t i o n / F o u nd a t i o n G r a n t s
ANNUAL DIREC T
COSTS
Favus, Murray
Rhodes, Christopher
Therapeutic Targeting of Carotid Body Chemoreflex for Sleep Disordered Breathing
Sharp, Willard
Bell, Graeme
Diabetes Center Summer Medical Student Program
Total PHS Research
SPONSORED RESE ARCH
S E C T I O N O F E N D O C R I N O L O G Y, D I A B E T E S & M E TA B O L I S M — P u b l i c H e a l t h S e r v i c e
S E C T I O N O F D E R M AT O L O G Y — P u b l i c H e a l t h S e r v i c e
He, Yu-Ying
P R I N C I PA L
AWARDS
$287,106
$13,500
$26,960
53
P R I N C I PA L
AWARDS
ANNUAL DIREC T
COSTS
ANNUAL INDIREC T
COSTS
Hypertension Fellowship Program (Servier)
$50,000
Relypsa Research Services Agreement
Van Cauter, Eve
Vokes, Tamara
55,430
$5,000
13,857
Circadian Function: Circadian Function and Cardio-Metabolic Risk in Adrenal Insufficiency: A Case
Control Study (Shire)
$66,109
$16,527
Circadian Function: Circadian Function and Cardio-Metabolic Risk in Adrenal Insufficiency: A Case
Control Study (Merck)
$110,496
$27,624
H80-MC-X021:Impact of Exenatide on Sleep and Circadian Function in Type 2 Diabetes (Lilly)
$125,380
$31,345
Effects of CPAP Treatment on Glucose Control in Patients with Type 2 Diabetes: A Randomized
Placebo-Controlled Study (Respironics)
$239,187
$59,797
PAR-C10-008 (RACE): A 12-Month Open-Label Study Investigating the Safety and Tolerability of
NPSP558, A Recombinant Human Parathyroid Hormone (rhPTH [1-84]), for the Treatment of Adults with
Hypoparathyroidism—A Clinical Extension Study (NPS Pharmaceuticals)
$40,712
ANNUAL INDIREC T
COSTS
Role of EGFR and miR-143/miR-145 Western Diet-Promoted Colonic Tumorigenesis
$201,276
Chang, Eugene
Research Training in Digestive Diseases and Nutrition.
$442,710
$26,763
IBD and Mucosal Inflammation, Immunology, and Micobiology of the G.I. Tract
$750,000
$420,000
Short Term Training: Health Professional Students
$200,070
$16,006
Dietary Fat Effects on Gut Microbes, Host Immune State and Experimental Colitis
$294,364
$156,607
Impact of Gut Microbes and Heat Shock Proteins on Mucosal Homeostasis and IBD
$247,500
$143,550
Innate and Adaptive Immunity in Celiac Disease
$205,425
$110,621
Jabri, Bana
GATA4 as a Window into the Link Between Metabolism and Immunity
Viral Infections and Celiac Disease Pathogenesis
Pharmacological Validation of Transglutaminase 2 as a Novel Target for Celiac Disease (Subcontract
with Stanford University)
$135,444
$35,311
$822,758
$199,639
Kim, Karen
Konda, Vani
S E C T I O N O F E N D O C R I N O L O G Y, D I A B E T E S A N D M E TA B O L I S M
SPONSORED RESE ARCH
ANNUAL DIREC T
COSTS
Bissonnette, Marc
$10,178
F Y 10
F Y 11
F Y 12
F Y 13
F Y 14
F Y 15
$13,224,098
$14,036,456
$12,355,171
$11,486,004
$8,849,865
$7,673,929
$1,033,797
$848,358
$505,210
$552,966
$597,615
$314,066
Industry Grants
$1,988,682
$1,440,402
$1,385,719
$1,345,983
$994,932
$1,022,397
T O TA L
$16,246,577
$16,325,216
$14,246,100
$13,384,953
$10,442,412
$9,010,392
S E C T I O N O F G A S T R O E N T E R O L O G Y, H E PAT O L O G Y & N U T R I T I O N — P u b l i c H e a l t h S e r v i c e
S E C T I O N O F E N D O C R I N O L O G Y, D I A B E T E S & M E TA B O L I S M — I nd u s t r y G r a n t s
Bakris, George
P R I N C I PA L
AWARDS
Chicago South Side Cancer Disparities Initiative
$116,739
$156,577
$81,420
$520,855
$168,615
$135,677
$78,693
$171,746
$99,613
Partnership for Healthier Asians
$202,775
$97,079
Biophotonics Study for Gastrointestinal Cancer Screening (Subcontract with Northwestern University)
$117,088
$67,912
Titanium Dioxide Based Nanoparticle Study for Colon Cancer Phototherapy (Department of Energy/
Argonne National Laboratories)
$15,000
$0
EDRN-Pre Validation Study (Subcontract with Boston University)
$62,600
$36,308
Kupfer, Sonia
Genetic Association Studies in African American Colorectal Cancer Patients
$152,200
$12,176
Kwon, John
IBD Gene Mapping by Population and Clinical Subsets (Subcontract with Johns Hopkins)
Li, Yanchun
$4,000
$2,320
New Drug VS-110 for Treating Inflammatory Bowel Disease (Subcontract with Vidaym)
$106,623
$61,841
Mechanism of Vitamin D Chemoprevention Against Colon Cancer
$264,255
$153,268
Pekow, Joel
Novel microRNA Regulatory Networks Predictive of Colon Carcinogenesis in IBD
$135,491
$10,839
Rubin, David
Methotrexate Response in Treatment of UC-MERIT-UC (Subcontract with the University of North
Carolina)
$11,455
$5,362
$4,397,687
$1,865,732
Total PHS Research
S E C T I O N O F G A S T R O E N T E R O L O G Y , H E PAT O L O G Y & N U T R I T I O N — S t a t e /A s s o c i a t i o n / F o u nd a t i o n G r a n t s
Chang, Eugene
Targeting Calpain-Induced Cleavage of HMGB1 Client Proteins to Restore Intestinal and Metabolic
Homeostasis in Inflammatory Bowel Diseases (Kenneth Rainin Foundation)
$90,909
$9,091
$608,410
$60,841
2014 HHMI Medical Research Fellows Program
$40,000
$0
The Impact of Crohn’s Disease-associated Genetic Polymorphisms on HMGB1-mediated
Inflammatory Responses in Intestinal Epithelial Cells (Crohn’s and Colitis Foundation)
$58,250
$0
Role of Intestinal Inflammation in the Pathogenesis of Type-1 Diabetes (Juvenile Diabetes Research
Foundation International)
$216,605
$6,383
PSC and IBD, a Genetic and Microbiome Analysis (Hemsley Charitable Trust)
Identification of Abberrant Tissue Responses to Intestinal Microbes that Cause Ulcerative Colitis
(Hemsley Charitable Trust)
Jabri, Bana
Kupfer, Sonia
$524,234
$52,423
Understanding the Underlying Defects that Trigger and/or Exacerbate IBD (Hemsley Charitable Trust)
$47,727
$2,273
2015 Early Career Development Award (Central Society for Clinical and
Translational Research)
$10,000
$0
$1,596,135
$131,011
Role of Gut Microbiota in DKT Chemoprevention of Colorectal Cancer (Tsumura USA, Inc)
$263,713
$105,485
The Effectiveness of Daikenchuto (Kampo) for Treatment of Experimental Inflammatory Bowel Disease:
Mediating Role of Enteric Microbiota (Tsumura USA, INC)
$279,362
$111,745
The Role of Entric Microbiota in Mediating the Biovailability and Actions of TU-100 (Tsumura USA Inc.)
S E C T I O N O F G A S T R O E N T E R O L O G Y , H E PAT O L O G Y & N U T R I T I O N — I nd u s t r y G r a n t s
Chang, Eugene
Cohen, Russell
54
$294,669
$117,868
2014 Visiting Professorship in Inflammatory Bowel Disease Center At the University of Chicago Medical
Center (UCB Pharma)
$11,600
$1,160
Advanced Practice Nurse and Physician Assistant IBD Immersion Program (AbbVie)
$68,182
$6,818
55
P R I N C I PA L
AWARDS
ANNUAL DIREC T
COSTS
ANNUAL INDIREC T
COSTS
S E C T I O N O F G A S T R O E N T E R O L O G Y , H E PAT O L O G Y & N U T R I T I O N — I nd u s t r y G r a n t s (continued)
HCV-TARGET: Hepatitis C Therapeutic Registry and Research Network-A Longitudinal, Observational
Study (University of Florida)
$43,566
$10,892
Reddy, Gauthem
MK5172: A Phase II/III Randomized Clinical Trial to Study the Efficacy and Safety of the Combination
Regiman of MK-5172 and MK-8742 in Subjects with Chronic Hepatitis C Virus Infection and Chronic Kidney
Disease (Merck)
$77,397
$19,349
Reau, Nancy
GS-US-342-1139: A Phase 3, Multicenter, Randomized, Open-Label Study to Compare the Efficacy
and Safety of Sofosbuvir/GS-5816 Fixed Dose Combination for 12 Weeks with Sofosbuvir and Ribavirin for
12 Weeks in Subjects with Chronic Genotype 2 HCV Infection (Gilead)
$56,606
$14,151
M14-222: An Open-Label, Multicenter Study to Evaluate Long-term Outcomes with ABT-450/Ritonavir/
ABT-267 (ABT-450/r/ABT-267) and ABT-333 With or Without Ribavirin (RBV) in Adults With Genotype 1
Chronic Hepatitis C Virus (HCV) Infection (TOPAZ II)-(AbbVie)
$197,218
Waxman, Irving
Advances in IBD Fellows Program (Janssen Biotech)
$22,727
$11,278
$225,000
$130,500
CHeSS: SIESTA (Sleep for inpatients: Educating Staff to Act)
$230,525
$18,442
A Church-Based, Self-Management Intervention for Mexican-Americans with Diabetes
$160,700
$12,856
Chin, Marshall
Improving Diabetes Care and Outcomes on the South Side of Chicago—Multi PI
$352,030
$197,137
Research and Mentorship in Improving Diabetes Care
$110,388
$8,831
$440,608
$189,183
$314,955
$182,674
Reducing Healthcare Disparities with Shared Decision Making (AHRQ)
HRSA Evaluation Studies IDIQ-Multi PI
$1,582
$918
Hong, Susan
Moving Forward: A Weight Loss Program for African American Breast Cancer Surviviors
(Subcontract with the University of Illinois)
$8,040
$4,663
Huang, Elbert
National Social Life, Health and Aging Project: Wave III (NORC)
$2,273
$6,818
$682
$31,818
$3,182
Comparative Effectiveness of Dynamic Patterns of Glucose Lowering Therapies (AHRQ)
2014 International Visiting Professorship in Inflammatory Bowel Disease (Janseen Biotech)
$12,650
$1,265
2014 Adv. IBD Fellowship Research Meeting (Shire Pharmaceuticals)
$21,265
$2,127
Treating To Target: Personallized IBD Care in 2015 (AbbVie)
$59,091
$5,909
C13008: A Phase 3, Open-label Study to Determine the Long-Term Safety and Efficacy of MLN0002 in
Patients with Ulcerative Colitis and Crohn’s Disease (Mill)
$60,148
$15,037
ALV003-1221: A Phase 2b, Randomized, Double-Blind, Placebo-Controlled Dose-Ranging Study of the
Efficacy and Safety of ALV003 Treatment in Symptomatic Celiac Disease Patients Maintained on a
Gluten-Free Diet (Alvine)
$51,686
Cook Endoscopy Medical Devices
$23,274
$9,310
$519,786
$129,990
$2,101,576
$619,469
S E C T I O N O F G A S T R O E N T E R O L O G Y , H E PAT O L O G Y & N U T R I T I O N
SPONSORED RESE ARCH
F Y 10
F Y 11
F Y 12
F Y 13
F Y 14
F Y 15
$5,075,143
$5,659,088
$4,821,521
$5,910,410
$6,970,714
$6,263,419
$1,106,400
$964,884
$1,295,436
$1,254,467
$1,592,639
$1,727,146
Industry Grants
$1,321,390
$1,213,634
$1,737,317
$2,414,585
$2,485,488
$2,721,045
$7,502,933
$7,837,606
$7,854,274
$9,579,462
$11,048,841
$10,711,610
T O TA L
$140,978
CHeSS: TEACH STRIVES: Spreading Teen-Research Inspired Videos to Engage Schoolmates
Baig, Arshiya
$49,305
$12,921
ANNUAL INDIREC T
COSTS
Environment and Perceived Control: Improving Sleep in Hospitalized Older Patients
The New Era of Individualized Care for the IBD Patient in 2013 (AbbVie)
ANNUAL DIREC T
COSTS
Chicago Center for Diabetes Translation Research
Visiting Professor Program (2013-2014)(Shire Pharmaceuticals)
Semrad, Carol
SEC TION OF GENER AL INTERNAL MEDICINE — Public Health Ser vice
Arora, Vineet
Jensen, Donald
Rubin, David
P R I N C I PA L
AWARDS
$90,364
$52,411
$285,394
$41,849
Case Studies on the Cost of Medical Home Transformation and Maintenance in the Safety Net (AHRQ)
$63,286
$36,706
Use of Public Health Technology to Support Chronic Disease Control (NORC)
$23,674
$13,731
Cohort Differences in Social Life and Health: Refreshing the NSHAP Sample (NORC)
$78,215
$45,365
HCIA Evaluations-Community Resource Planning
$126,582
$73,418
Laiteerapong, Neda
Linking the Legacy Effect in Type 2 Diabetes to Clinical Decision Making
$163,040
$13,043
Peek, Monica
Improving Diabetes Care and Outcomes on the South Side of Chicago-Multi PI (see Chin)
Sulmasy, Daniel
Understanding Optimism in Clinical Research (Oregon Health and Science University)
Total PHS Research
$10,999
$6,380
$2,826,360
$1,039,385
S E C T I O N O F G E N E R A L I N T E R N A L M E D I C I N E — S t a t e /A s s o c i a t i o n / F o u nd a t i o n G r a n t s
Arora, Vineet
SIESTA-Sleep for Inpatients: Educating Staff to Act (American Sleep Medical Foundation)
$69,444
$5,556
Chin, Marshall
Improving Diabetes Care and Outcomes on the South Side of Chicago (Merck Company
Foundation)—Multi PI
$260,623
$39,093
CHeSS: Finding Answers: Disparities Research for Change (Robert Wood Johnson Foundation)
$187,655
$22,519
Rewarding Equity Through Payment and Delivery System Reform (Robert Wood Johnson Foundation)
$419,347
$50,322
Novel Education and Diabetes Pilot Program for Latinos at the Barbara Center for Pediatric Diabetes
(Helmsley Charitable Trust)
$12,980
$1,298
Innovative Clinical Care Approach for Young Adults with Type 1 Diabetes: The DTC (Diabetes Telehealth
Care Beyond High School) Study (Helmsley Charitable Trust)
$97,367
$9,737
Hey Doc, Pay Attention to Me: Teaching Relationship-Centered Electronic Medical Record Use to
Faculty Providers (Central Group Educational Affairs)
$5,000
$0
Evaluating a Patient-Centered Electronic Medical Record (EMR) Use Curriculum (Clerkship Directors
Internal Medicine)
$4,500
$0
$25,000
$0
$1,841
$0
Huang, Elbert
Lee, Wei Wei
Improving Patient-Centered Technology Use (iPaCT) Curriculum (Arnold P. Gold Foundation)
Impact of Technology Use on the Patient-Doctor Relationship and Communtication (Arnold P. Gold
Foundation)
Peek, Monica
Improving Diabetes Care and Outcomes on the South Side of Chicago (Merck Company
Foundation)—Multi-PI (see Chin)
Rossi-Foulkes, Rita
Mental Health Care for Adults with Developmental Disabilities (Special Hope Foundation)
Sulmasy, Daniel
Towards Medicine as a Spiritual Practice: The Project on Medicine and Religion Clinical Scholars
Program (John Templeton Foundation)—Multi-PI
Vela, Monica
2014 AOA Fellow in Leadership Award—Promoting Diversity in the U.S. Physician Population (Alpha
Omega Alpha Medical Society)
$33,333
$6,667
$662,203
$33,711
$25,000
$0
$1,804,293
$168,903
$83,405
$33,362
$83,405
$33,362
S E C T I O N O F G E N E R A L I N T E R N A L M E D I C I N E — I nd u s t r y G r a n t s
Huang, Elbert
56
The Multiple Daily Injections and Continuous Glucose Monitoring in Diabetes: DlaMonD Study
(Dexcom)
57
AWARDS
P R I N C I PA L
Dale, William
F Y 10
F Y 11
F Y 12
F Y 13
F Y 14
F Y 15
$2,005,050
$4,024,891
$3,305,486
$3,381,291
$3,539,210
$3,865,745
$3,950,379
$3,930,492
$4,059,920
$4,656,872
$4,971,991
$1,973,196
Industry Grants
T O TA L
P R I N C I PA L
Grossman, Robert
$150,600
$150,600
$124,459
$0
$0
$116,767
$6,106,029
$8,105,983
$7,489,865
$8,038,163
$8,511,201
$5,955,708
ANNUAL DIREC T
COSTS
ANNUAL INDIREC T
COSTS
$743,487
$311,544
ACE: Interdisciplinary Studies of Insistence on Sameness in Autism (Subcontract with University of
Illinois at Chicago)
$25,606
$14,851
Pharmacogenomics of Arrhythmia Therapy (Subcontract with Vanderbilt)
$46,088
$25,809
Pharmacogenomics of Arrhythmia Therapy (Subcontract with University of California
San Francisco)
$25,000
$14,500
Leveraging Functional Genetic Variation to Elucidate the Genetic Architecture of T2D among Mexican
Americans
$40,495
$0
$564,483
$103,069
Harnessing GTEx to Create Transcriptome knowledge and Inform Disease Biology—Multi-PI
Open Science Data Cloud (OSDC) PIRE: Training & Workshops in Data Intensive Computing Using the
OSDC (National Science Foundation)
UCSC-ENCODE (Subcontract with University of California, Santa Cruz)
Thompson, Katherine
Dale, William
$35,894
$20,819
National Social Life, and Aging Project: Analyses of Wave 1 and Wave 2 (NORC)
$73,642
$42,712
$15,679
Current State Assessment and Pilot of Supportive Cancer Care Processes (Distress, Palliative, Hospice
Referral and Survivorship Care) at The University of Chicago Medicine (Coleman Foundation)
$139,972
$0
Gorawara-Bhat, Rita
Person Centered Communications with Older Persons in need of Health Care. Development of a
Research Based Education Platform (Norwegian Research Council)
$22,883
$3,432
Huisingh-Scheetz, Megan
Advance Planning for Home Services for Seniors (Patient-Centered Outcomes Research Institute/
Northwestern University)
$29,341
$11,736
Levine, Stacie
A Primary Palliative Care Education Program to Improve Access for Patients with Cancer (Coleman
Foundation/Rush University)
$75,434
$0
University of Chicago Palliative Medicine Hearst Fellowship (Academy of Hospital Palliative Medicine)
$37,750
$0
Development of a Patient-Centered Care Planning Tool for Multimorbid Patients (John A. Hartford
Foundation)
$10,000
$0
$451,578
$30,847
Thompson, Katherine
$0
$252,698
$140,765
$95,015
$55,108
Conte Center for Computational Systems Genomics of Neuropsychiatric Phenotypes
$1,525,347
$432,794
Industry Grants
Big Machine Science (Defense Advanced Research Projects Agency)
$1,447,365
$431,489
T O TA L
$841,982
$488,349
$25,393
$14,728
$21,769,368
$5,455,223
Total PHS Research
$71,995
$39,198
$3,338,928
Genetics of Gene Expression in Human Left Ventricular Myocardium (Subcontract with Brigham &
Women’s Hospital)
$184,889
Improving Communication for Chemotherapy: Addressing Concerns of Older Cancer Patients and
Caregivers (PCORI)
$56,042
The Genetic Basis of Cross-tissue Protein Expression Variability in Humans—Multi-PI
$5,639
$0
$15,867,827
MAPGen Knowledge Base (MAPGenKB) and Coordination Center (Subcontract with University of
Southern California)
$2,825
$70,483
$97,000
$81,969
Discovery of Genomic Copy Number Variants and Expression Quantitative Trait loci that Affect
Warfarin Dose Response in African Americans
Teaching Interdisciplinary Care for Frail, Urban Older Adults
$4,870
The John A. Hartford Foundation Center of Excellence in Geriatrics Program Award (American
Federation for Aging Research)
$168,025
Health Disparity in Pharmacogenomics: African American SNPs and Drug Metabolism
Stranger, Barbara
Reducing Chemotherapy Toxicity in Older Adults (University of Rochester)
S E C T I O N O F G E R I AT R I C S & PA L L I AT I V E M E D I C I N E — S t a t e /A s s o c i a t i o n / F o u nd a t i o n G r a n t s
$1,320
The Open Genomic Data Commons (OGDC)
Rzhetsky, Andrey
ANNUAL INDIREC T
COSTS
Total PHS Research
$44,515
BigData:Small:DCM:Open Flow Enabled Hadoop over Local and Wide Area Cluster (National Science
Foundation)
Perera, Minoli
ANNUAL DIREC T
COSTS
Geriatric Assessment-Driven Interventions for Older Cancer Patients (University of Rochester)
SEC TION OF GENE TIC MEDICINE — Public Health Ser vice
Cox, Nancy
S E C T I O N O F G E R I AT R I C S & PA L L I AT I V E M E D I C I N E — P u b l i c H e a l t h S e r v i c e
SEC TION OF GENER AL INTERNAL MEDICINE
SPONSORED RESE ARCH
AWARDS
S E C T I O N O F G E R I AT R I C S & PA L L I AT I V E M E D I C I N E
F Y 10
F Y 11
F Y 12
F Y 13
F Y 14
F Y 15
SPONSORED RESE ARCH
$424,297
$527,812
$463,209
$297,606
$259,781
$256,884
$422,165
$631,601
$312,500
$352,400
$363,803
$482,425
$0
$0
$0
$0
$0
$0
$846,462
$1,159,413
$775,709
$650,006
$623,584
$739,309
S E C T I O N O F G E N E T I C M E D I C I N E — S t a t e /A s s o c i a t i o n / F o u nd a t i o n G r a n t s
Cox, Nancy
Computational Pharmacogenomics of Neuropsychiatric Disorders (Burroughs Welcome Fund)
$4,302
$0
Rzhetsky, Andrey
The Conte Center on the Computational Systems Genomics of Psychiatric Disorders (Chicago
Biomedical Consortium)
$200,650
$0
$204,952
$0
SEC TION OF GENE TIC MEDICINE
SPONSORED RESE ARCH
Industry Grants
T O TA L
58
F Y 10
F Y 11
F Y 12
F Y 13
F Y 14
F Y 15
$9,971,201
$6,021,469
$7,028,822
$7,174,640
$28,224,370
$27,224,591
$88,224
$143,224
$1,002,996
$1,248,301
$252,603
$204,952
$0
$0
$0
$0
$0
$0
$10,059,425
$6,164,693
$8,031,818
$8,422,941
$28,476,973
$27,429,543
59
P R I N C I PA L
AWARDS
ANNUAL DIREC T
COSTS
ANNUAL INDIREC T
COSTS
$42,828
$24,840
S E C T I O N O F H E M AT O L O G Y/ O N C O L O G Y — P u b l i c H e a l t h S e r v i c e
PACTTE-Partnership for Anemia Clinical and Translational Trials in the Elderly
Catenacci, Daniel
PANGEA: Personalized Antibodies for GastroEsophageal Adenocarcinoma Pilot Trial
$156,600
$12,528
Chen, Jianjun
The Role and Functional Mechanisms of a miRNA Cluster, mir-17-92 in Leukemogenesis
$207,974
$116,220
$42,676
$0
Conzen, Suzanne
Dolan, Eileen
Potential Therapuetic Implications of Targeting miR-150 in Acute Myeloid Leukemia
$242,070
$101,152
Glucocorticoid Receptor-mediated Survival Signaling in Breast Cancer
$143,400
$83,172
Identifying Mechanisms Linking Stress Biology to Human Breast Cancer
$200,799
$108,862
$77,946
$45,209
Genetic Susceptibility and Biomarkers of Platinum-related Toxicities (University of Rochester)—Multi-PI
PAAR - Pharmacogenomics of Anticancer Agents Research Group—Multi-PI (see Ratain)
Kindler, Hedy
Cancer Center: U10-NCTN (Lead)
$497,437
$288,513
Kline, Justin
Characterization of a T cell Dysfunctional State Induced in Mice with AML
$201,275
$116,739
Larson, Richard
Stopping Tyrosine Kinase Inhibitors in CMP Patients (Subcontract with the Medical College
of Wisconsin)
$15,861
$9,201
Le Beau, Michelle
CC: The Coding, Decoding, Transfer, and Translation of Information in Cancer (Subcontract with
$35,000
$19,600
Lim-Seiwert,Tanguy
P13K Pathway Mutations in Head and Neck Cancer (Subcontract with the University of Pittsburgh)
$7,219
$4,187
Maitland, Michael
Computational Modeling of Tumor Burden by CT to Advance Cancer Therapeutics
$506,927
$106,228
$9,536
$5,531
The 1200 Patients Project:Studying Clinical Implementation of Pharmacogenomics
$174,345
$13,948
Commercialization Investigation of the Genomic Prescribing System (National Science Foundation)
$45,000
$5,000
Novel Role of Compensatory Proliferation in Human Brain Tumor (Subcontract with Ohio
State University)
O’Donnell, Peter
Olopade, Olufunmilayo
Patrick-Miller, Linda
Basic Medical Oncology Research Training in Medical Oncology-Multi PI
$394,884
$29,431
Using Genomics to Reduce Breast Cancer Disparities in the African Diaspora-Multi-PI
$530,396
$260,851
Developing an Oncology Workforce for the 21st Century-Multi-PI
$772,955
$61,836
International Partnership for Interdisciplinary Research Training
$209,851
$10,683
The Cancer Genome Atlas Program
$90,924
$52,736
Cancer Genetics Professional Education in a Global Community of Practice (Subcontract with Beckman
Institute)
$25,000
$2,000
$5,516
$3,199
Virtual Cancer Genetic Services: Telemedicine Delivery in Community Clinics (Subcontract with
University of Pennsylvania)
Communicating Genetic Test Results by Telephone: A Randomized Trial (Subcontract with
Breast Cancer Family Registry Cohort (Subcontract with Fox Chase Center)
LEGACY: A Cohort of Youth in Families From the Breast Cancer Family Registry
Returning Genetic Research Panel Results for Breast Cancer Susceptibility (Subcontract with
Ratain, Mark
PAAR-Pharmacogenomics of Anticancer Agents Research Group—Multi-PI
PGRN Translational Pharmacogenetics Program (TPP)—Multi-PI
ANNUAL DIREC T
COSTS
ANNUAL INDIREC T
COSTS
$150,000
$30,000
$18,104
$0
Development of microRNA-nanoparticles to Treat Childhood Acute Leukemia Carrying MLL
Rearrangements (Alex’s Lemonade Stand)
$125,000
$0
Therapeutic Potential of miR-150 in Treating MLL-rearranged Leukemias (Leukemia & Lymphoma
Foundation)
$180,018
$19,982
Churpek, Jane
Characterizing the Contribution of Mutations in Cancer Predisposition Genes to Therapy-related
Myeloid Neoplasms (Cancer Research Foundation)
$25,000
$0
Conzen, Suzanne
Targeting Stress Receptor Biology: A Novel Approach in Poor Prognosis TNBC (Susan Komen)
$180,000
$45,000
$47,501
$2,499
$52,834
$30,644
$8,963
$5,198
Chen, Jianjun
The Role of miR-126 in Core-Binding Factor(CBF) Acute Myeloid Leukemia (American Cancer Society)
The Role of APL-specific microRNAs in ATRA Treatment (Gabrielle’s Angel Foundation for Cancer
Research)
The Role of Glucocorticoid Receptor Signaling in High Grade Serous Ovarian Carcinoma (Conquer
Cancer Foundation)
$500,000
$0
Dolan, Eileen
Use of selective GR Antagonists in Castration-Resistant Prostate Cancer (Prostate Cancer Foundation)
Identification of Chemical Entities Protective of Paclitaxel-Induced Peripheral Neurophathy (Chicago
Biomedical Consortium)
$10,000
$0
Godley, Lucy
Identifying Germline Mutations in Young Patients with Myelodysplastic Syndromes (Cancer Research
Foundation)
$17,500
$0
Epigenetic Control of Hematopoietic Stem Cell Function (Wells Fargo)
$91,667
$18,333
North American Consortium for Familial Hematologic Malignancies (Cancer Research Foundation)
$75,000
$0
Huang, Rong Stephanie
Longitudinal Transcriptomics of Imatinib Response in Chronic Myeloid Leukemia (Searle Funds at the
Chicago Community Trust)
$15,000
$0
Jakubowiak, Andrzej
Multiple Myeloma Research Consortium Site Grant (Multiple Myeloma Research Foundation/
Karyopharm)
$77,199
$7,720
Li, Zejuan
The Roles and Potential Targets of TET1 and TET2 in MLL-rearranged leukemia (American Cancer
Society)
Liu, Hongtao
Proteomics Research Program (Multiple Myeloma Research Foundation)
$83,333
$16,667
$100,000
$0
The Role of Prophylactic Donor Lymphocyte Infusion on the Immune Re-Constitution and Minimal
Residual Disease Control after T-Cell Depleted Stem Cell Transplant for High Risk Patients with Hematologic Malignancies (Cancer Research Foundation)
$37,500
$0
Nakamura, Yusuke
The Histone Epigenome as a Novel Therapeutic Target in Head and Neck Cancer (Conquer Cancer
Foundation)
$47,501
$2,499
Nanda, Rita
The Breast Cancer Clinical Trials Consortium (Breast Cancer Research Foundation/Johns Hopkins)
$46,167
$9,233
O Donnell, Peter H.
International Drug Induced Renal Injury Consortium (DIRECT) (“Network”) (International
SAE Consortium)
$15,000
$0
2015 Early Career Development Award (Central Society for Clinical and Translational Research)
$10,000
$0
Toward a Primary Prevention of Breast Cancer in the African Diaspora (American Cancer Society)
$80,000
$0
Translating Breast Cancer Genetics In The Clinic (Susan Komen Foundation)
$166,112
$33,888
$208,333
$41,667
$4,800
$7,229
$4,192
$135,332
$78,493
$1,278,655
$670,917
$51,000
$29,580
Clinical Downstaging of Breast Cancer Through Education in Southwestern Nigeria (Doris Duke
Charitable Trust)
$60,000
$50,000
$0
$41,329
$23,971
$500,000
$0
$113,636
$11,364
$4,651
$349
Developing an Infrastructure to Conduct Clinical Breast Cancer Trials in Resource Poor Nations such
as Nigeria (Breast Cancer Research Foundation)
Experimental Therapeutics: Clinical Trials Network with Phase I Emphasis—Multi-PI
$322,785
$187,215
Developing Biomarkers for Early-Detection of Aggressive Breast Cancer (Noreen Fraser Foundation)
Salgia, Ravi
P13K as a Therapeutic Target in Malignant Pleural Mesothelioma—Multi-PI
$100,000
$58,000
The Cancer Genome Atlas Program (SAIC)
Sharma, Manish
Genomic Prediction Tools Developed Using Phenotypes from Disease Progression Models
$179,100
$14,328
Smith, Sonali
MAP Kinease Signaling in Lymphoma: A Novel Therapeutic Paradigm (Subcontract with Tufts University)
$4,528
$2,626
Stadler, Walter
Coordinating Center Application for Prostate Cancer Research Program Clinical Consortium Award
(Department of Defense)
$64,003
$37,122
Early Therapeutics Development with a Phase II Emphasis
$312,387
$163,656
Does the Androgen Receptor(AR)regulated Map Kinase Phosphatase 1 (MKP-1) Enhance Castration
Resistant Prostate Cancer Survival under Therapeutic Stress? (Department of Defense)
$75,000
$43,500
A Pharmacokinetic/Pharmacodynamic Study of the Glucocorticoid Receptor Antagonist Mifepristone
Combined with Enzalutamide in Castrate Resistant Prostate Cancer (Department of Defense)
$149,455
$86,684
VanderWeele, David
The Genomic Evolution of Prostate Cancer (Department of Defense)
$130,000
$75,400
Vokes, Everett
Translational Meta-analysis for Elderly Lung Cancer Patients (Subcontract with Duke University)
$5,063
$2,937
Wheeler, Heather
Pharmacogenomics of the Chemotherapeutic Agent Paclitaxel
Wickrema, Amittha
The Role of Dock4 in Normal and Aberrant Erythropoiesis
Szmulewitz, Russell
Improving HbF Induction by Better Selection and Inhibition of Epigenetic Targets
(Subcontract with Cleveland Clinic)
Total PHS Research
60
S E C T I O N O F H E M AT O L O G Y/ O N C O L O G Y — S t a t e /A s s o c i a t i o n / F o u n d a t i o n G r a n t s
Artz, Andrew
The Oncogenic Role of miR-9 in MLL-Associated Leukemias
P R I N C I PA L
AWARDS
$53,942
$0
$327,075
$71,050
$18,987
$11,013
$7,912,757
$3,054,221
Genomics, Metabolomics and Epigenetic Regulation in Breast Cancer (Falk Medical Research
Foundation)
National Women’s Cancer Research Alliance (Entertainment Industry Foundation)
Patrick-Miller, Linda
Risk, Benefits and Utilities of Multiplex Testing for Breast Cancer Susceptibility
(Conquer Cancer Foundation)
Polite, Blase
The Role of Deferring to God’s Control in Disparities in Colon Cancer (John Templeton Foundation)
$161,820
$14,706
Salgia, Ravi
Common Bone Marrow Homing Pathways for HSC and SCLC Stem Cells (Chicago Community Trust
Searle Funds)
$25,000
$0
EPHA2 as a Novel Therapeutic Target in Malignant Pleural Mesothelioma (Mesothelioma Applied
Research Foundation)
$50,000
$0
$66,110
$0
Saloura, Vassiliki
The Role of WHSC1-mediated Histone H1 methylation in Squamous Cell Carcinoma of the Head and
Neck (Cancer Research Foundation)
61
P R I N C I PA L
AWARDS
ANNUAL DIREC T
COSTS
ANNUAL INDIREC T
COSTS
S E C T I O N O F H E M AT O L O G Y/ O N C O L O G Y — S t a t e /A s s o c i a t i o n / F o u n d a t i o n G r a n t s (continued)
Sharma, Manish
Stock, Wendy
Thirman, Michael
$37,500
$0
CALGB 50901: A Phase II Trial of Ofatumumab in Previously Untreated Follicular Non-Hodgkin’s
Lymphoma (Alliance for Clinical Trials in Oncology Foundation)
$41,808
$4,181
TOPK (T-LAK cell-orginated protein kinase): A new target for FLT3 mutated AML (V Foundation for
Cancer Research)
$181,818
$18,182
CALGB 10001: Quantitative RT-PCR for BCR-ABL in Samples Collected from Philadelphia Positive Acute
Lymphoblastic Leukemia Patients Enrolled on a Phase II Trial of Sequential Chemotherapy, Imatinib
Mesylate (Gleevec, STI571) (NSC# 716051, IND# 61135), and Transplantation for Adults with Newly
Diagnosed PH+ Acute Lymphoblastic Leukemia by the CALGB and SWOG/Novartis Study Number
CSTI157AUS281T (Cancer & Leukemia Group B Foundation)
$82,500
$8,250
Peptide and Small Molecule Therapeutics for MLL-Associated Leukemia (Leukemia & Lymphoma
Foundation)
$180,018
$19,982
CT-mediated Low Dose Radiation-induced Adaptive Responses Impact On Chemotherapy (ASH
Foundation)
$100,000
$0
VanderWeele, David
The Molecular Characterization of Ductal Adenocarcinoma of the Prostate (Cancer Research
Foundation}
$41,923
$0
Wickrema, Amittha
Nuclear Opening Histone Release in Mammalian Terminal Erythropoiesis (Chicago Community
Trust-Searle Funds)
$40,000
$0
$4,084,048
$333,273
Catenacci, Daniel
OncoPlex Diagnostics: OncoPlexDx Project ID: Work Order No.3 (Expression Pathology)
$17,500
$7,000
$52,500
20070622/ AMG 102: A Phase 3, Multicenter, Randomized, Double-Blind, Placebo Controlled Study
of Rilotumumab (AMG 102) with Epirubicin, Cisplatin, and Capecitabine (ECX) as First-line Therapy in
Advanced MET-Positive Gastric or Gastroesophageal Junction
Adenocarcinoma (Amgen)
$41,260
$10,315
EMR 200095-001: A Phase I Open-Label, Non-Randomized, Dose Escalation First-in-Man Trial to
Investigate the c-Met Kinase Inhibitor EMD1214063 Under Two Different Regimens in Subjects with
Advanced Solid Tumors (Serono)
$62,544
$15,636
$71,160
$17,790
20101132: A Phase 1, First-in-Human Study Evaluating the Safety, Tolerability, and Pharmacokinetics of
AMG 337 in Adult Subjects with Advanced Solid Tumors (Amgen)
Towards Personalized Therapy of Gastroesophageal Adenocarcinoma (Genentech)
OncoPlex Dx Project ID: Work Order No. 7 (Expression Pathology)
$89,889
$35,956
$100,000
$40,000
De Souza, Jonas
D4200L0057/ISSZACT0016: Randomized Placebo-Controlled Phase II Study of ZD6474 as a
Chemopreventive Agent for Premalignant Lesions of the Head and Neck (Astra Zeneca)
$87,706
$21,927
Fleming, Gini
B1271004: A Randomized Phase 2 Non-Comparative Study of the Efficacy of PF-04691502 and
PF-05212384 in Recurrent Endometrial Cancer (Pfizer)
$42,400
$10,600
SGI-110-02: A Randomized, Controlled, Open-Label, Phase 2 Trial of SGI-110 and Carboplatin in Subjects
with Platinum-Resistant Recurrent Ovarian Cancer (Astex)
$45,890
$10,908
INCB 24360-201: A Phase 1/2 Randomized, Blinded, Placebo Controlled Study of Ipilimumad in
Combination with INCB024360 or Placebo in Subjects with Unrectablable or Metastatic Melanoma
(Incyte)
$74,980
$18,745
II-ON Resource Model Agreement (BMS)
$94,536
$23,634
NO25395B: A Phase 1B, Open Label, Dose-Escalation Study Evaluating the Safety, Tolerability and
Pharmacokinetics of R05185426 in Combination with GDC-0973 When Administered in Patients with
BRAF V600E-Positive Metastatic Melanoma Who Have Progressed After Treatment with R05185426
(Genentech)
$103,609
$25,902
CA223001: A Phase I Dose Escalation and Cohort Expansion Study of the Safety, Tolerability and Efficacy
of Anti-KIR (BMS-986015) Administered in Combination with Anti-PD-1 BMS-936558) in Advanced Refractory Solid Tumors (BMS)
$358,513
$89,628
Godley, Lucy
Analyzing 5-hydroxymethylcytosine Content after Rigosertib treatment (Onconova)
$27,037
$10,815
Hahn, Olwen
11-PIR-11: The Beacon Study (Breast Cancer Outcomes with NKTR-102): A Phase 3 Open-label,
Randomized, Multicenter Study of NKTR-102 Versus Treatment of Physician’s Choice (TPC) in Patients
with Locally Recurrent or Metastatic Breast Cancer Previously Treated with Anthracycline, a Taxane
and Capecitabine (Nektar)
$67,776
$16,944
Jakubowiak, Andrzej
KPT-CFZ: A Phase I Study of the Combination of a Selective Inhibitor of Nuclear Export (SINE), Selinexor
with Carfilzomib and Dexamethasone in Patients with Relapsed or Relapsed/Refractory Multiple
Myeloma (Onyx)
$65,349
$21,162
CRd+Transplant: Open-label, Single-arm, Phase 2 Study of the Consolidation and Maintenance
Treatment with Carfilzomib, Lenalidomide and Low dose Dexamethasone (CRd) in transplant Candidates
with Newly Diagnosed, Multiple Myeloma Requiring Systemic Chemotherapy (Onyx)
$58,421
$36,086
CRd+Transplant: Open-label, Single-arm, Phase 2 Study of the Consolidation and Maintenance
Treatment with Carfilzomib, Lenalidomide and Low dose Dexamethasone (CRd) in transplant Candidates
with Newly Diagnosed, Multiple Myeloma Requiring Systemic Chemotherapy (Onyx)
$160,925
$18,750
VS6063-104: A Phase 1 Dose Escalation Study of VS-5584, a Dual PI3K/m TOR Inhibitor, Administered
With a Fixed Dose of VS-6063, A Focal Adhesion Kinase Inhibitor, In Subjects with Relapsed Malignant
Mesothelioma (Verastem)
$43,368
$10,842
VS-6063-202: A Phase II Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of VS-6063
in Subjects with Malgnant Pleural Mesothelioma (Verastem)
$43,632
$10,908
ADU-CL-02: A Phase 1B Study to Evaluate the Safety and Induction of Immune Response of CRS-207
in Combination with Pemetrexed and Cisplatin as Front-line Therapy in Adults with Malignant Pleural
Mesothelioma (Biotech)
$50,226
$12,557
EMR 200066-003: Phase II Randomized Trial of MEK Inhibitor MSC1936369B of Placebo Combines with
Gemcitabine in Metastatic Pancres Cancer Subjects (Serono)
$77,025
$19,256
15051: An Open Label Phase I Dose Escalatin Study to Evaluate the Safety Tolerability Pharmacokinetics
Pharmacodynamics and Maximum Tolerated Dose of the Anti Mesothelin
Antibody Drug Conjugate BAY94-9343 in Subjects with Advanced Solid Turmors (Bay)
$212,990
$53,248
ADU-CL-04: A Phase 2B, Randomized, Controlled, MultiCenter, Open-Label Study of the Efficacy
and Immune Response of GVAX Pancrease Vaccine (with Cyclophophamide) and CRS-207 Compared
to Chemotherapy or to CRS-207 Alone in Adults with Previously-Treated Metastic Pancreatic
Andeocarcinoma (Adurobiotech)
$274,219
$68,555
TREME (D4880C00003): A Phase 2, Randomized, Double-blind Study Comparing Tremelimumab to
Placebo in Second- or Third-line Treatment of Subjects with Unresectable Pleural or Peritoneal
(Medimmune)
$353,166
$88,291
Kindler, Hedy
ANNUAL INDIREC T
COSTS
$131,250
Evaluation of MET expression and gene copy number in gastroesophageal tissues (Amgen,Inc)
Gajewski, Thomas
62
ANNUAL DIREC T
COSTS
S E C T I O N O F H E M AT O L O G Y/ O N C O L O G Y — I n d u s t r y G r a n t s
Disease Progression Models for Biomarkers and Patient Reported Outcomes in Cancer Patients
(Cancer Research Foundation)
P R I N C I PA L
AWARDS
63
P R I N C I PA L
AWARDS
ANNUAL DIREC T
COSTS
ANNUAL INDIREC T
COSTS
ANNUAL DIREC T
COSTS
ANNUAL INDIREC T
COSTS
A8081005: Phase 2, Open Label Single Arm Study of the Efficacy and Safety of PF-02341066 in Patients
with Non-Small Cell Lung Cancer Harboring a Translocation or Inversion involving the Anaplastic
Lymphoma Kinase (EML4-ALK) Gene Locus (Pfizer)
$42,738
$10,685
S E C T I O N O F H E M AT O L O G Y/ O N C O L O G Y — I n d u s t r y G r a n t s (continued)
Salgia, Ravi
Larson, Richard
2215-CL-0101: A Phase I/2 Open-Label, Dose Escalation Study Investigating the Safety, Tolerability,
Pharmacokinetics, and Pharmadynamics of ASP2215 in Patients with Relapsed or Refractory Acute
Myeloid Leukemia (Astellas)
$178,323
$44,581
Lim-Seiwert, Tanguy
MK-3475-012-04: A Phase Ib Multi-Cohort Study of MK-3475 in Subjects with Advanced Solid Tumors
(Merck)
$626,560
$156,640
T13387-05: A Study of Hsp90 Inhibitor AT13387 Alone and in Combination with Crizotinib in the Treatment
of Non-small Cell Lung Cancer (NSCLC)(Astex)
$56,761
$14,190
PIM4604g: An Open Label Phase 1, Dose Escalation Study Evaluating the Safety and Tolerability of GDC
0980 Administered Once Daily in Patients with Refractory Solid Tumors or Non-Hodgkins Lymphoma
(Merck)
$176,668
$44,167
A7471042: A Phase 2, Multi Cohort Study to Evaluate the Impact of Prophylactic Intervention on
Dermatologic and Gastrointerstinal Advers Events and Patient Reported Outcomes in Patients Treated
with Dacomitinib (Pfizer)
$65,826
$16,457
KCP 330-008: A Randomized, Open Label, Phase 2 Study Of The Selective Inhibitor Of Nuclear Export
(Sine) Selinexor (KPT-330) Versus Specified Physician’s Choice In Patients 60 Years Old With Relapsed/
Refractory Acute Myeloid Leukemia (Aml) Who Are Ineligible For Intensive Chemotherapy And/Or
Transplantation (K Pharma)
$60,633
$15,158
AP26113-11-101: A Phase 1/2 Study of the Safety, Tolerability, Pharmacokinetics and Preliminary Anti-Tumor
Activity of the Oral ALK/EGFR Inhibitor AP26113. (Ariad)
$80,359
$20,090
9090-08:A Randomized Phase 2/3 Study of STA-9090 in Combination with Docetaxel verus Doocetaxel
Alone in Subjects with Stage IIIB or IV Non-Small Cell Lung Cancer (Arm B)(Synta)
$84,674
$21,168
KCP 330-008: A Randomized, Open Label, Phase 2 Study Of The Selective Inhibitor Of Nuclear Export
(Sine) Selinexor (KPT-330) Versus Specified Physician’s Choice In Patients 60 Years Old With Relapsed/
Refractory Acute Myeloid Leukemia (Aml) Who Are Ineligible For Intensive Chemotherapy and/or
Transplantation (Medimmune)
$61,406
CRLX101: A Randomized Phase II Study of IV Topotecan versus CRLX101 in the Second Line Treatment of
Recurrent Small Cell Lung Cancer (Cerulean)
$92,912
$23,228
$113,131
$28,283
A4061068: A Phase 1B, Open Label, Dose Escalation Study to Evaluate Safety, Pharmacokinetics and
Pharmacodynamics of Axitinib (AG-013736) in Combination with Crizotinib (PF-02341066) in Patients with
Advanced Solid Tumors (Pfizer)
$54,964
$13,741
M12-375: A Multicenter, Phase 1/1b, Open-Label, Dose-Escalation Study of ABT-700, a Monoclonal
Antibody, in Subjects with Advanced Solid Tumors (Abbott)
CO-1686: A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral
CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)(Clovis)
$115,823
$28,956
20090277: An Open-Label Parmacokinetic Study of AMG 386 in Advanced Cancer Subjects with Normal
and Impaired Renal Function (Amgen)
$57,078
$14,270
OncoPlex Diagnostics:OPDx Project ID:PRO20120725_13 (Expression Pathology)
$28,000
$11,200
$85,714
$34,286
DS8273-A-U101: Phase 1, Open-Label Study to Assess the Safety and Tolerability of DS-8273a in Subjects
with Advanced Solid Tumors or Lymphomas (Daiic)
$66,557
Liu, Hongtao
Luke, Jason
Maitland, Michael
$15,351
Studies of novel TK inhibitors in upper aerodigestive malignancies (Methyl Gene, Inc)
$16,639
M10-944: A Phase I Study Evaluating the Safety and Pharmacokinetics of ABT-348 as Monotherapy,
in Combination with Carboplatin/Gemcitabine or in Combination with Docetaxel in Subjects with
Advanced Solid Tumors (Abbott)
$122,933
$30,733
A3026-CL-0101: A Phase I, Multicenter, Open-Label, Dose Escalation Study of ASP3026 in Subjects with
Advanced Malignancies (Astellas)
$141,348
$35,337
OTS167: “Phase 1, Single-Center, Cohort Dose Escalation Trial to Determine the Safety, Tolerance,
and Preliminary Antineoplastic Activity of OTS167, a MELK Inhibitor, in Patients with Refractory Locally
Advanced or Metastatic Solid Tumor Malignancies (Oncotherapy)
$419,822
$104,956
Nahban,Chadi
Prospective, Multi-Center Phase I/II Trial of Lenalidomide and Dose-Adjusted EPOCH-R in MYCassociated B-cell Lymphomas (Celgen)
$111,910
$27,977
Nanda, Rita
CO-3810-02: A Phase 2,Randomized, Open-label, Multicenter, Safety and Efficacy Study of Oral Lucitanib
in Patients with FGF Aberrant Metastatic Breast Cancer (Clovis)
$132,219
$33,055
Nakamura, Yusuke
Development of New Targeted Cancer Therapies (OncoTherapy Sciences)
$1,240,277
$496,111
Characterization of T Cell Receptor (TCR) Repertoire (Shionogi)
Odenike, O
O’Donnell, Peter
$300,467
$120,187
NS-018-101(Phase 2): A Phase 1/2, Open-label, Dose-escalation, Multi-center Study to Assess the Safety,
Tolerability, Pharmacokinetics, and Pharmacodynamics of Orally Administered NS-018 in Patients with
Primary Myelofibrosis, Post-polycythemia Vera Myelofibrosis, or Post-essential Thrombocythemia (NS
Pharmaceuticals)
$46,755
$11,689
ASTX727: A Phase 1-2 Pharmacokinetic guided Dose-Escalation and Dose-Confirmation Study of
ASTX727, a Combination of the Oral Cytidine Deaminase Inhibitor (CDAI) E7727 with Oral Decibabine in
Subjects with Myelodysplastic Syndromes (Astex)
$68,383
$17,096
VOS-AML-301(VALOR): A Phase 3, Randomized, Controlled, Double-Blind, Multinational Clinical Study of
the Eddicacy and Safety of Vosaroxin and Cytarabine Versus Placebo and Cytarabine in Patients with
First Relapsed or Refarctory Acute Myeloid Leukemia (Sunesis)
$85,355
$21,339
13-0540/1200.171: Afatinib in Advanced Refractory Urothelial Cancer (Nipi)
GO29293: A Phase II, Multicenter, Single-Arm Study of MPDL3280A in Patients with Locally Advanced or
Metastatic Urothelial Bladder Cancer (Celgene)
$90,975
$22,744
$202,189
$50,547
West African Breast Cancer Collaboration (Novartis Pharmaceuticals)
$55,853
$22,342
Ratain, Mark
DCR-MYC-101: Phase I, Multicenter, Cohort Dose Escalation Trial to Determine the Safety, Tolerance,
and Maximum Tolerated Dose of DCR-MYC, a Lipid Nanoparticle (LNP)-Formulated Small Inhibitory RNA
(siRNA) Oligonucleotide Targeting MYC, in Patients with Refractory Locally Advanced or Metastatic
Solid Tumor Malignancies, Multiple Myeloma, or Lymphoma (Dicerna)
$134,615
$33,654
Ninth International Workshop on Pharmacodynamics of Anticancer Agents (Daiichi Sankyo)
64
P R I N C I PA L
AWARDS
$9,091
$909
$242,370
$96,948
Sharma, Manish
Janssen Statement of Work #1 (Janssen Research & Development, LLC)
CA 186-018: A Phase 1b, Open-Label, Multicenter Study of Urelumab (BMS-663513) in Combination with
Cetuximab in Subjects with Advanced/Metastatic Colorectal Cancer or Squamous Cell Carinoma of the
Head and Neck (BMS)
$50,970
$12,742
Smith, Sonali
KCP-330-009: A Phase 2b Study of Selinexor (KPT-330) with Low Dose Dexamethasone (Sel-Dex) in
Patients with Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)(Karyo)
$63,763
$15,941
Stadler, Walter
A Phase II Randomized Study of MPDL3280A Administered in Monotherapy or in Combination with
Bevacizumab Versus Sunitinib in Patients with Untreated Advanced Renal Cell Carcinoma (Roche)
$66,974
$16,744
D5082C00002: A Phase II Trial to Evaluate the Efficacy of AZD6094 (HMPL-504) in Patients with Papillary
Renal Cell Carcinoma (PRCC)(Astra Zeneca)
$78,500
$19,625
B1931010: An Open-Label, Phase I Study of Inotuzumab Ozogamicin in Subjects with Relapsed or
Refractory CD22-Positive Acute Lymphocytic Leukemia (Pfizer)
$52,788
$13,197
$130,534
$32,634
$41,140
$10,285
9785-CL-0121: A Phase 2 Open-Label Extension Study to Assess the Safety of Continued Administration
of MDV3100 in Subjects with Prostate Cancer who Showed Benefit From Prior Exposure to MDV3100
(Astellas)
$53,082
$13,271
Thirman, Michael
GS-US-312-0133: A Phase 2, Single Arm Study Evaluating the Efficacy and Safety of Idelalisib in
Combination with Rituximab in Patients with Previously Untreated Chronic Lymphocytic Leukemia with
17p Deletion (Gilead)
$89,214
$22,304
Villaflor, Victoria
CRAD001CUS132T: Selection of Chemoradiotherapy Based on Response to Induction Chemotherapy—
a Randomized Phase 2 Study in Locally Advanced Squamous Cell Carcinoma of the Head and Neck
(Novartis)
$55,000
$13,750
OPTIMA: An Exploratory Pilot Study of Nab-Paclitaxel Based Induction Chemotherapy Followed by Response-Stratified Locoregional Therapy for Patients with Stage III and IV HPV-Related Oropharyngeal
Cancer—The OPTIMA HPV Trial (Celgene)
$61,830
$15,457
CA209-141: An Open Label, Randomized Phase 3 Clinical Trial of Nivolumab vs Therapy of Investigator’s
Choice in Recurrent or Metastatic Platinum-refractory Squamous Cell Carcinoma of the Head and Neck
(SCCHN)(BMS)
$42,364
$10,591
CA209-017-0100: An Open-label Randomized Phase III Trial of BMS-936558 versus Docetaxel in
Previously Treated Metastatic Non-small Cell Lung Cancer (NSCLC)(BMS)
$115,573
$29,893
$186,230
$61,870
Stock, Wendy
SGI-110-01: A Phase I, Dose Escalation, Multicenter Study of Two Subcutaneous Regimens of SGI-110, a
DNA Hypomethylating Agent, in Subjects with Intermediate of High-Risk Myelodysplastic Syndromes
(MDS) or Acute Myelogeneous Leukemia (AML)(Supergen)
Szmulewitz, Russell
Vokes, Everett
The CATCH Prostate Cancer Trial: Cabazitaxel And Tasquinimod in Men with Castration-Resistant Heavily
Pre-treated Prostate Cancer (Duke)
RV-HN-PI-0477: Phase II Study of Cetuximab and Lenalidomide in Recurrent/Metastatic Squamous Cell
Carcinoma of the Head and Neck (Celgene)
65
P R I N C I PA L
AWARDS
ANNUAL DIREC T
COSTS
ANNUAL INDIREC T
COSTS
NPI-0052-101: A Phase I Clinical Trial of NPI-0052 in Patients With Relapsed/Refractory Multiple Myeloma.
(Nureus)
$44,631
Perifosine 127: An Open-Label, Phase I Study of the Safety of Perifosine in Combination with
Lenalidomide and Dexamethasone for Patients with Relapsed or Refractory Multiple Myeloma (AOI)
$48,660
TED10893: A Phase 1/2 Dose Escalation Safety, Pharmacokinetic and Efficacy Study of Multiple Intravenous Administrations of a Humanized Monoclonal Antibody (SAR650984) Against CD38 in Patients with
Selected CD38+ Hematological Malignancies (Sanofi)
BT-062-983: A Phase I/IIa Multi-dose Escalation Study of BT062 in combination with Lenalidomide and
Dexamethasone in Subjects with Relapsed or Relapsed/Refractory Multiple Myeloma (Biotest)
$11,158
$51,652
$12,165
Meltzer, David
$12,913
Tools for Optimizing Medication Safety (HRSA/Northwestern)
ANNUAL INDIREC T
COSTS
$76,915
$19,229
$3,281,508
$818,531
$12,799,388
$3,564,969
F Y 11
F Y 12
F Y 13
F Y 14
F Y 15
$16,852,215
$16,569,314
$16,656,275
$15,938,742
$14,977,477
$10,966,978
$5,970,386
$6,441,810
$6,853,894
$5,185,461
$5,172,107
$4,417,321
$7,728,249
$5,104,544
$7,367,316
$10,426,362
$15,648,868
$16,364,357
$30,550,850
$28,115,668
$30,877,485
$31,550,565
$35,798,452
$31,748,656
$76,087
$44,130
$722,325
$118,813
Short-Term Aging-Related Research Program
$60,021
$4,802
CHeSS: Open Source Science: Transforming Chronic Illness Care (Subcontract with Cincinnati Children’s
Hospital)
$96,237
$53,893
CHeSS: The University of Chicago Patient Centered Outcome Research K12 Training Program (AHRQ)
F Y 10
Industry Grants
Gibbons, Robert
CHeSS: A New Statistical Paradigm for Measuring Psychopathology Dimensions in Youth
S E C T I O N O F H E M AT O L O G Y/ O N C O L O G Y
T O TA L
ANNUAL DIREC T
COSTS
$598,738
$47,899
$1,368,298
$714,616
$227,598
$14,368
$19,375
$11,238
NIH Intergovernmental Personnel Act
$98,496
$0
Using EHR Data to Dynamically Target Patients for Braden Scale Risk-Assessment (AHRQ)
$67,530
$0
CHeSS: Integrated Inpatient/Outpatient Care for Patients at High Risk of Hospitalization
Health Services Training Grant Subaward (Subcontract with Northwestern University)
SPONSORED RESE ARCH
S E C T I O N O F H O S P I TA L M E D I C I N E — P u b l i c H e a l t h S e r v i c e
Zimmerman, Todd
P R I N C I PA L
AWARDS
Changing Long-Term Care in America: Policies, Markets, Strategy & Outcomes (Subcontract with Brown
University)
Pho, Mai Tuyet
Optimizing Patient-Oriented Outcomes for Chronic Hepatitis C
Press, Valerie
Video vs. TTG Respiratory Inhaler Technique Assessment and Instruction (V-TRAIN)
$111,184
$8,735
$144,200
$11,536
Shih, Ya-Chen Tina
CHeSS: Reducing Tobacco Related Health Disparities (Subcontract with University of Texas MD
Anderson)
$15,639
$8,758
Using Claims Data to Evaluate Radiation Therapy Utilization at the End of Life (Subcontract with
University of Texas)
$10,566
$5,916
CHeSS: Smoking Cessation for Cervical Cancer Survivors in a Safety Net Healthcare System
(Subcontract with MD Anderson)
$20,211
$11,722
Yoga for Women with Breast Cancer Undergoing Radiotherapy (Subcontract with University of Texas
MD Anderson)
$4,355
$2,526
$3,640,860
$1,058,952
Total PHS Research
S E C T I O N O F H O S P I TA L M E D I C I N E — S t a t e /A s s o c i a t i o n / F o u nd a t i o n G r a n t s
Meltzer, David
Pho, Mai Tuyet
Press, Valerie
Shih, Ya-Chen Tina
Home Care by Comprehensive Care Physicians (Retirement Research Foundation)
$36,014
$3,601
CAPriCORN: Chicago Area Patient Centered Outcomes Research Network (PCORI)
$317,833
$127,133
Program in Oral Health, Systemic Health, Well-Being and the Social Sciences (George Richmond
Foundation)
$729,472
$0
Multi-Pathogen Point-of-Care Diagnostics(MPDx)in East Africa (Grand Challenges Canada)
$5,345
$695
Patient-focused Modeling for Hepatitis C (Central Society for Clinical and Translational Research)
$10,000
$0
INVITE Home: Investigating Novel Video Modules on Inhalers To Educate at Home (American Lung
Association)
$40,000
$0
Coordinated Healthcare Interventions for Childhood Asthma Gaps in Outcomes (Chicago) Trial (PCORI/
University of Illinois)
$128,612
$51,444
CHeSS: Innovative Methods for Modeling Longitudinal Medical Costs (Northwestern University)
$80,144
$46,484
$1,347,420
$229,357
$66,800
$26,720
S E C T I O N O F H O S P I TA L M E D I C I N E — I nd u s t r y G r a n t s
Edelson, Dana
Memorandum of understanding resuscitation quality programs trial (Laerdal Medical LTD)
Press, Valerie
Epidemiology and Inpatient Management for Patients Hospitalized for Acute Asthma (Novartis)
$2,500
$1,000
$22,320
$5,580
$91,620
$33,300
S E C T I O N O F H O S P I TA L M E D I C I N E
SPONSORED RESE ARCH
Industry Grants
T O TA L
66
F Y 10
F Y 11
F Y 12
F Y 13
F Y 14
F Y 15
$2,654,155
$6,523,959
$6,881,204
$7,262,725
$5,010,872
$4,699,812
$536,898
$324,233
$33,740
$240,960
$650,872
$1,576,777
$405,786
$280,786
$215,311
$195,311
$0
$124,920
$3,596,839
$7,128,978
$7,130,255
$7,698,996
$5,661,744
$6,401,509
67
P R I N C I PA L
AWARDS
ANNUAL DIREC T
COSTS
ANNUAL INDIREC T
COSTS
S E C T I O N O F I N F E C T I O U S D I S E A S E S & G L O B A L H E A LT H — P u b l i c H e a l t h S e r v i c e
David, Michael
Recurrent MRSA Infections: A Study of Risk Factors and Molecular Epidemiology
Pitrak, David
$9,380
University of Chicago Program for Expanded Human Immunodeficiency Testing for Disproportionately
Affected Populations in Healthcare Settings in Chicago (Chicago Department of Public Health)
$930,351
$169,649
Social Network Dynamics, HIV and Risk Reduction Among Younger Black MSM (Subcontract with NORC)
$30,886
$17,913
$35,912
$20,829
Ridgway, Jessica
Anti-infective Stewardship using the Wisca tool in the Electronic Medical Record (Subcontract with
NorthShore University HealthSystem)
Schneider, John
Hybridized Cell Phone and Survey Generated Communication Network
$132,392
$34,167
Social Network Positional Selection of Peer Change Agents
$149,829
$42,825
Sherer, Renslow
Network Supported Engagement in HIV Care for Younger Black Men—Multi-PI
$158,910
$68,949
Next Generation Partner Notification and Intervention Services
$150,000
$87,000
YMAP: Young Men’s Affiliation Project of HIV Risk & Prevention Venue (Subcontract with University of
Texas)
$118,888
$66,170
$9,072
$5,262
Preventing HIV Transmission by Recently-Infected Drug Users (NORC)
$100,408
Public Health Targeting of PrEP at HIV Positives’ Bridging Networks
$164,493
$58,774
HIV Intervention Models for Criminal Justice Involved Substance-using Black MSM
$498,676
$204,912
$65,394
$5,232
$2,662,461
$850,308
MATEC Project (Subcontract with the University of Illinois at Chicago)
Total PHS Research
$59,246
S E C T I O N O F I N F E C T I O U S D I S E A S E S & G L O B A L H E A LT H — S t a t e /A s s o c i a t i o n / F o u nd a t i o n G r a n t s
Ridgway, Jessica
What’s Going Around? (Rice Foundation/NorthShore University Health)
Schneider, John
Sustainable Health Center Implementation PrEP Pilot (SHIPP) Study (CDC Foundation)
$35,000
Rapid Response Team and Algorithmic HIV Post-test Counseling in High-volume Settings (Gilead
Sciences)
Sherer, Renslow
WUMER Project (Sino American Medical School, Wuhan University)
$0
$21,737
$2,174
$227,273
$22,727
$1,038,984
$0
$1,322,994
$24,901
S E C T I O N O F I N F E C T I O U S D I S E A S E S & G L O B A L H E A LT H — I nd u s t r y G r a n t s
Mullane, Kathleen
Pitrak, David
$175,957
$43,989
V212-011: A Phase III, Randomized, Placebo-Controlled, Clinical Trial to Study the safety and Efficacy of
V212 in Adult Patients with Solid Tumor or Hematologic Malignancy (Merck)
$133,956
$33,489
CMX-001-301: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter, Phase 3
Study of the Safety, Tolerability, and Efficacy of CMX001 for the Prevention of Cytomegalovirus (CMV)
Infection in CMV-seropositive (R+) Hematopoietic Stem Cell Transplant Recipients. (Chimerix)
148,101
37,025
OPT-80-302:DEFLECT-1: A Phase 3b Multi-Center, Double-Blind, Randomized, Placebo Controlled Study
to Demonstrate the Safety and Efficacy of Fidaxomicin for Prophylaxis against CLostridium difficilEAssociated Diarrhea in Adults Undergoing Hematopoietic Stem Cell Transplantation (Chimerix)
43,254
10,813
LCD-CDAD-10-07: A Randomized, Double-Blinded, Active-Controlled Study Of CB-183,315 In Patients
With Clostridium Difficile Associated Diarrhea (Cubist)
79,354
19,839
Expanded Testing and Linkage to Care (XTLC) (Gilead Sciences)
ANNUAL DIREC T
COSTS
ANNUAL INDIREC T
COSTS
Chapman, Arlene
Limited Competition for the Continuation of the Consortium for Radiologic Imaging
$256,785
$74,760
Cunningham, Patrick
Endothelial Injury in Endotoxin-Induced Acute Renal Failure
$207,364
$116,124
Hammes, Mary
A Clinical and Computational Study to Improve Brachiocephalic Fistula Outcomes
$486,224
$84,163
Hassan, Hatim
Calcium Oxalate Kidney Stones: Pathogenesis of Obesity-associated Hyperoxaluria
$217,500
$126,150
Kohn, Orly
Longitudinal Changes in Intra-Renal Oxgenation by BOLD MRI in Patients with CKD (Subcontract with
NorthShore University Health System)
$47,475
$21,827
Toback, F. Gary
A Novel Agent with Dual Functions to Treat Head and Neck Cancer
$130,500
$75,690
Worcester, Elaine
Pathogenisis of Calcium Nephrolithiasis
$1,161,912
$264,496
$2,507,760
$763,210
Total PHS Research
S E C T I O N O F N E P H R O L O G Y — S t a t e /A s s o c i a t i o n / F o u nd a t i o n G r a n t s
Chapman, Arlene
$30,625
$12,250
$227,296
$22,730
$365,904
$91,476
$1,204,447
$271,611
Medical Research Grant Regarding Polycystic Kidney Disease (Allen Foundation)
$301,567
$0
$301,567
$0
S E C T I O N O F N E P H R O L O G Y — I nd u s t r y G r a n t s
Josephson, Michelle
University of Chicago Nephrology Research Conference (Alexion Pharmaceuticals)
$2,273
$227
Kohn, Orly
HUS-TTP and TMAs/Nephrology Research Conference (Alexion Pharmaceuticals)
$2,364
$236
Koyner, Jay
Validation of the Furosemide Stimulation Test: A Physiologic Biomarker for Acute Kidney injury (Satellite
Healthcare)
$86,957
$13,043
$167,099
$41,775
$258,693
$55,281
SEC TION OF NEPHROLOGY
SPONSORED RESE ARCH
F Y 10
F Y 11
F Y 12
F Y 13
F Y 14
F Y 15
$3,450,643
$2,776,571
$3,839,952
$3,561,111
$3,237,178
$3,270,970
$651,496
$672,996
$455,800
$280,000
$75,000
$301,567
Industry Grants
$120,220
$115,864
$182,979
$99,167
$114,900
$313,974
$4,222,359
$3,565,431
$4,478,731
$3,940,278
$3,427,078
$3,886,511
T O TA L
OPT-80-302:DEFLECT-1: A Phase 3b Multi-Center, Double-Blind, Randomized, Placebo Controlled
Study to Demonstrate the Safety and Efficacy of Fidaxomicin for Prophylaxis against CLostridium
difficilE-Associated Diarrhea in Adults Undergoing Hematopoietic Stem Cell Transplantation (Optimer)
Cytotoxin Activity in Stool in C.diff colitis: Clinical correlates (Viropharma)
SEC TION OF NEPHROLOGY — Public Health Ser vice
$117,250
Social and Cultural Influences on Cardiovascular Risk Factors in South Asians (Subcontract with
P R I N C I PA L
AWARDS
S E C T I O N O F I N F E C T I O U S D I S E A S E S & G L O B A L H E A LT H
SPONSORED RESE ARCH
Industry Grants
T O TA L
68
F Y 10
F Y 11
F Y 12
F Y 13
F Y 14
F Y 15
$70,967
$174,657
$497,255
$1,169,471
$1,314,576
$3,512,769
$512,861
$1,398,666
$1,704,158
$1,625,573
$1,693,056
$1,347,895
$484,549
$603,547
$922,682
$2,270,925
$1,362,267
$1,476,058
$1,068,377
$2,176,870
$3,124,095
$5,065,969
$4,369,899
$6,336,722
69
P R I N C I PA L
AWARDS
ANNUAL DIREC T
COSTS
ANNUAL INDIREC T
COSTS
S E C T I O N O F P U L M O N A R Y/ C R I T I C A L C A R E — P u b l i c H e a l t h S e r v i c e
P R I N C I PA L
AWARDS
ANNUAL DIREC T
COSTS
ANNUAL INDIREC T
COSTS
$56,034
$14,009
$0
S E C T I O N O F P U L M O N A R Y/ C R I T I C A L C A R E — I nd u s t r y G r a n t s
Allen, Michael
The Role of Toxic Ion Channels in ALS Pathogenesis
$206,872
$115,848
Birukov, Konstantin
Mechanisms of Prostacyclin-Mediated Lung Endothelial Barrier Protection
$245,000
$142,100
Control of Lung Permeability by Oxidized Phospholipids
$250,000
$145,000
EMPROVE: A Prospective, Randomized, Controlled Multicenter Clinical Study to Evaluate the Safety
and Effectiveness of the IBV valve System for the Single-Lobe Treatment of Severe Emphysema
(Spiration)
Birukova, Anna
Microtubule-associated Rac Regulation and Acute Lung Injury
$239,480
$138,898
Interventional Pulmonology Fellowship at The University of Chicago (Boston Scientific)
$30,000
Churpek, Matthew
Predicting in-hospital Cardiac Arrest Using Electronic Health Record Data
$119,950
$9,596
Interventional Pulmonology Fellowship at The University of Chicago (Pinnacle Biologics)
$30,000
$0
Fang, Yun
miR-10a Regulation of Regional Arterial Endothelial Phenotyes in Atherosclerosis
$154,234
$89,456
$22,727
$2,273
Hamanaka, Robert
Metabolic Regulation of Epidermal Homeostasis
$78,488
$6,279
Murgu, Septimiu
Interventional Pulmonology Fellowship at The University of Chicago (Cook Medical)
Howell, Michael
Quantifying a Vital Symptom: Large-scale Inpatient Dyspnea Measurement (Subcontract with
Beth Israel)
$11,375
$6,598
Mokhlesi, Babak
HRC-1006-AutoOHS-MS: Randomized Controlled Trial of AutoOHS vs. CPAP vs. Bilevel Support
Ventilation in Obesity Hypoventilation Syndrome (Respironics)
$293,415
$130,681
Noth, Imre
De-identified DNA (Intermune Pharmaceuticals)
$11,036
$4,414
$3,510
$0
Strek, Mary
GS-US-332-0207 (Rainier): GS-US-332-0207 (Rainier): A Phase 2, Randomized, Double-Blind, PlaceboControlled, Multi-Center Study to Assess the Efficacy and Safety of GS-6624 in Subjects with Idiopathic
Pulmonary Fibrosis (Gilead)
$44,494
$11,123
PIPF-031: A Treatment Protocol to Allow Patients in the US with Idiopathic Pulmonary Fibrosis Access
to Pirfenidone (Intermune)
$52,430
$13,107
Knutson, Kristen
Home Sleep and Circadian Phase: Mediators of Racial Disparities in Diabetes Risk
McConville, John
Assessing Resident Physician Melanoma Detection Across Ethnic Groups (Subcontract with University
of Illinois at Chicago)
McShane,Pamela
Genetic Disorder of Mucocilary Clearance (Subcontract with University of North Carolina)
Mokhlesi, Babak
Impact of Sleep in the Restoring Insulin Secretion (RISE) Study
Mutlu, Gokhan
Noth, Imre
$21,537
$11,645
$280,657
$107,816
Cannabimimetic Treatment of Obstructive Sleep Apnea: A Proof of Concept Trial (Subcontract with
$7,912
$4,589
TODAY (Treatment Options for type 2 Diabetes in Adolescents and Youth) (Subcontract with George
Washington University)
$17,723
$10,279
Mechanisms of Airborne Particulate Matter Induced Thrombosis
$239,336
$125,898
Regulation of IL-6 and DNA and RNA Methylation by PM-induced Mitochondrial ROS
$166,107
$88,119
Signaling in the Lung Induced by Particulate Matter Air Pollution (Subcontract with Northwestern
University)
$22,978
$13,327
Mitochondrial Metabolism and ROS Regulate Lung Cancer (Subcontract with Northwestern University)
$11,489
$6,664
Rituximab Therapy in Patients with IPF (Subcontract with University of Pittsburgh)
$41,149
$18,213
Treatment of IPF with Laparoscopic Anti-reflux Surgery (University of California at San Francisco)
$157,902
$52,105
Olopade, Christopher
Summer Program to Increase Diversity in Biomedical Research & Physician Workforce
$129,700
$10,376
Solway, Julian
Re-Engineering Translational Medicine at the University of Chicago
$3,013,292
$1,175,211
Preclinical Development of Myosolvins, A New Class of Medicine for Asthma
$1,378,752
$382,621
Chicagoland Metropolitan AsthmaNet Consortium (CMAC)(Subcontract with Northwestern University)
Training of Junior Faculty for Careers in Omics of Lung Diseases-Multi PI
Sperling, Anne
$174,028
$97,455
$250,000
$20,000
Research Training in Respiratory Biology
$622,064
$47,205
Functional Genomics of IL-33 Expression and Asthma Risk-Multi PI
$453,380
$262,960
$400,000
$186,826
Tasali, Esra
Sleep Extension To Reduce Diabetes and Obesity Risk
Verhoef, Philip
AADRC Steering Committee IOF Award (Subcontract with NIAID & University of Texas)
White, Steven
Airway Inflammation and HLA-G in Asthma
Total PHS Research
$50,000
$29,000
$1,398,320
$811,025
$10,438,650
$4,245,790
$26,000
$0
Hogarth, Kyle
Interventional Pulmonology Fellowship at The University of Chicago (Covidien)
Vij, Rekha
Prognostic Biomarkers in Autoimmune-Featured Interstitial Lung Disease (Genentech)
$9,091
$909
$119,246
$29,811
$46,000
$4,000
$206,234
$49,934
$627,292
$129,580
S E C T I O N O F P U L M O N A R Y/ C R I T I C A L C A R E
SPONSORED RESE ARCH
F Y 10
F Y 11
F Y 12
F Y 13
F Y 14
F Y 15
$30,020,239
$24,651,285
$24,656,738
$12,820,284
$12,807,833
$14,684,440
$1,425,622
$580,478
$314,256
$671,855
$565,646
$806,778
Industry Grants
$1,636,663
$535,428
$540,346
$323,429
$874,585
$756,872
$33,082,524
$25,767,191
$25,511,340
$13,815,568
$14,248,064
$16,248,090
T O TA L
S E C T I O N O F P U L M O N A R Y/ C R I T I C A L C A R E — S t a t e /A s s o c i a t i o n / F o u nd a t i o n G r a n t s
Dulin, Nickolai
Regulation of Pulmonary Fibrosis by Cardiac Glycosides (American Heart Association of Greater
Midwest)
Naureckas, Edward
Cystic Fibrosis Foundation Practice Guidelines Update (Cystic Fibrosis Foundation Therapeutics, Inc)
$25,521
$0
Patient Powered Research Network for Chronic Obstructive Pulmonary Disease (COPD Foundation)
$6,196
$2,478
Noth, Imre
PFF Care Center Network Charter Agreement (Pulmonary Fibrosis Foundation)
$4,348
$652
Olopade, Christopher
Household Air Pollution from Burning Biomass: Implications for Maternal Health and Pregnancy
Outcome (United Nations Foundation)
$461,268
$28,815
Genetic and Epigenetic Factors in Breast Cancer (Breast Cancer Research Foundation)
$208,333
$41,667
$1,500
$0
$733,166
$73,612
White, Steven
Identification of the Metabolic Fingerprint of the Sputum Microbiome from Patients with Cystic Fibrosis
(Cystic Fibrosis Foundation)
70
71
ANNUAL DIREC T
COSTS
ANNUAL INDIREC T
COSTS
S E C T I O N O F R H E U M AT O L O G Y — P u b l i c H e a l t h S e r v i c e
Alegre, Maria-Luisa
Role of NF-kB Activation in Acute Allograft Rejection
$222,750
$124,740
T O TA L S P O N S O R E D
RESE ARCH
Impact of Microbiota on Alloimmune Responses in Transplantation
$250,000
$139,432
Clark, Marcus
In vivo Functions of lg-beta Ubiquitinylation
$217,095
$120,347
Medical Scientist National Research Service Award
$959,520
$43,161
$53,942
$0
PEARL: Pathway Exploration and Analysis in Renal Lupus
$50,000
$29,000
Regulation of Ig-kappa Recombination During B Lymphopoiesis
$297,607
$164,244
Mechanisms of B Cell Responses in Autoimmune Disease: University of Chicago and Autoimmunity Center of
Excellence–Collaborative Project M14-LN-UCH (Subcontract with Duke University)
$146,520
$84,982
In Situ Adaptive Immunity in Human Lupus Tubulointerstitial Nephritis
$220,000
$127,600
$287,911
$166,988
$204,029
$84,917
The Role of B-catenin/Tcf-1 Signaling in T-Cell Leukemia/Tymphoma
$127,434
$73,912
How B-catenin Expands Foxp3+RORgammat Pro-inflammatory T-regulatory cells
$305,547
$125,370
Huang, Haochu
Thymic B Cells and T Cell Selection
$267,975
$142,956
Wilson, Patrick
ARRA Systems Biological Analyses of Innate and Adaptive Responses to Vaccination (Subcontract with
Emory University)
$54,367
$30,446
$100,000
$58,000
Toward a Universal Influenza Virus Vaccine (Subcontact with Mt. Sinai)
$240,232
$139,335
Mechanisms of Broadly Neutralizing Humoral Immunity Against Influenza Viruses (Subcontract with
Mt. Sinai)
$348,043
$196,297
$10,000
$5,800
$361,465
$209,650
$4,724,437
$2,067,177
University of Chicago Autoimmunity Center of Excellence
Regulation of Cyclin D3 in B Lymphocyte Development
Vaccine Induced Immunity in the Young and Aged (Subcontract with Emory University)
Impact of Prior Influenza Exposures on Antibody Repertoires to New Viral Strains (Subcontract with
Wistar Institute)
NIAID Centers of Excellence in Influenza Research and Surveillance (Subcontract with Rochester
University)
F Y 10
F Y 12
F Y 13
F Y 14
F Y 15
$99,434,831
$96,056,715
$96,829,513
$84,200,394
$99,058,571
$96,631,536
$18,098,201
$18,048,656
$18,778,206
$17,676,921
$17,232,123
$14,652,238
Industry Grants
$15,128,421
$10,434,138
$14,019,304
$19,068,845
$22,810,505
$24,574,680
G R A N D T O TA L
$132,661,453
$124,539,509
$129,627,023
$120,946,160
$139,101,199
$135,858,454
F Y 15 T O TA L S P O N S O R E D R E S E A R C H AWA R D S
$140.0
$18
$26,000
$0
Reduced Avidity Endogenous Graft-specific T Cells in Transplantation Tolerance (American Heart
Association)
$26,000
$0
Epigenetic and Gene Expression Profiling of Pathogenic T Regs in Colon Cancer Patients (Chicago
Community Trust/Searle Funds)
$15,000
$0
Mapping the Regulation of Wnt signaling with B-Cat-eleon: a fluorescent B-catenin “timer” (Chicago
Community Trust/Searle Funds)
$50,000
$0
Huang, Haochu
MULTI-PI: Identifying Immune Evasion Mechanisms in Tumors Via a Genome-Wide shRNA Screen
(Chicago Community Trust Searle Funds)
$79,759
$0
Utset, Tammy
Rheumatology Fellowship Training Award (American College of Rheumatology)
$25,000
$0
Wilson, Patrick
The Impact of Staphylococcus aureus Infective Endocarditis on Human B Cell Responses (American
Heart Association)
$26,000
$0
$247,759
$0
$80.0
$20.0
$0.0
F Y 15
Public Health Ser vice
$35.0
$31.8M
$30.0
$4.3M
ed
ic
in
io
e
us
Gl D
ob is
al ea
H se
ea s
lth /
N
Pu
ep
hr
lm
ol
on
og
ar
y
y/
Cr
iti
ca
lC
ar
e
Rh
eu
m
at
ol
og
y
gy
co
ct
lM
fe
In
ta
pi
os
ol
at
em
H
H
og
y/
lia
al
/P
cs
ri
at
ri
Ge
On
tiv
e
ed
M
tic
ne
lo
Ca
in
ic
ic
ed
Ge
lM
na
er
re
e
e
in
gy
lo
ro
te
nt
lI
ra
$7,219,025
y
$6,277,420
en
$7,793,079
og
$7,861,148
ro
$6,570,355
ol
$179,652
$6,105,325
st
$262,105
in
$338,446
y
$317,230
$0.74M
og
$170,131
nc
$247,759
$362,340
ol
$6,791,614
$364,532
at
$5,650,783
$345,742
ge
$7,108,891
$677,416
er
$6,866,502
$802,248
Em
$5,597,976
$733,712
gy
$5,009,273
$7.2M
$6.3M
$3.9M
$1.03M
$0.0
rm
F Y 15
lo
F Y 14
De
F Y 13
io
F Y 12
rd
F Y 11
Ca
F Y 10
$6.4M
$6.0M
$4.87M
cr
$45,562
$10.7M
$9.0M
Ga
$134,090
$10.0
e
$13,456
$16.2M
$15.0
in
$32,106
$53,825
$20.0
do
$80,265
$25.0
ne
F Y 14
State/Association/Foundation Grants
Ge
72
F Y 13
S P O N S O R E D R E S E A R C H AWA R D S B Y S E C T I O N ( T O TA L C O S T S )
S E C T I O N O F R H E U M AT O L O G Y
T O TA L
F Y 12
Industr y Grants
$5.0
Industry Grants
F Y 11
ic
$96.6
$60.0
En
Explorations of Bc1-2 Expression and Its Prognostic Utility in Humans Lupus Nephritis (Abbott Laboratories)
$99.0
$84.4
ed
S E C T I O N O F R H E U M AT O L O G Y — I n d u s t r y G r a n t s
SPONSORED RESE ARCH
$14.6
$27.4M
Clark, Marcus
$17.7
$96.8
$96
$17.2
$40.0
In Millions
Gounari, Fotini
$19.1
$100.0
$99
$24.6
$121.0M
$18.8
$18
$135.8M
$22.8
$14.0
$10
F Y 10
Tracking the Fate and Function of Endogenous Graft-specific T Cells During Maintenance and Loss of
Transplant Tolerance (American Heart Association)
$129.6M
$124.5M
$15
$120.0
S E C T I O N O F R H E U M AT O L O G Y — S t a t e /A s s o c i a t i o n / F o u nd a t i o n G r a n t s
Alegre, Maria-Luisa
$139.1M
$132.7M
M
Gounari, Fotini
F Y 11
In Millions
Identification and Functional Analysis of Novel Determiners of B Lymphopoiesis
AWARDS
T H E D E PA R T M E N T O F M E D I C I N E
y
P R I N C I PA L
AWARDS
73
COMMITTEE HIGHLIGHTS
Di ver sit y C ommit te e
The Department of Medicine actively promotes diversity,
community-based research and understanding toward eliminating
health care disparities. The goal of the Diversity Committee is
to build upon the long tradition of excellence in the fields of
clinical care, research and education by working to improve
diversity among all programs in the Department. With outstanding
leadership from Monica Vela, MD, associate vice chair for
diversity, the Department of Medicine has enjoyed dramatic
success in the recruitment of a diverse house staff and faculty. In
addition, the Diversity Committee serves to focus and promote
Department activities that improve recruitment, retention,
scholarship, leadership and mentorship of qualified minority
students, house staff and faculty in an environment rich with
cultural awareness and sensitivity.
K e y h i g h l i g h t s f r o m F Y 15 i n c l u d e :
• Arshiya Baig, MD—Recipient of the Midwest SGIM Advocacy
and Community Service Award
• Monica Peek, MD—Recipient of Greenwall Faculty Scholar
in Bioethics
• Karen Kim, MD—Served as a panelist for the Institute of Medicine’s
• Milda Saunders, MD—Winner of the 2015 SGIM Unified
roundtable on the Promotion of Health Equity and the
Leadership Training in Diversity Award
Elimination of Health Disparities and the program committee for John Schneider, MD—Named the recipient of the 2015
•
the AACR Conference on The Science of Cancer Health Disparities Department of Medicine Diversity Award
in Racial/Ethnic Minorities and the Medically Underserved
• Monica Vela, MD—Recipient of the AOA Leadership Fellow
• Sola Olopade, MD—Awarded an NIH grant to support a summer Award, and appointed to the Midwest Regional Board of the
program to increase diversity in biomedical research and
National Hispanic Medical Association
physician workforce at the Pritzker School of Medicine
Wom en’s C ommit te e
Under the leadership of Helen Te, MD, the Department of
is comprised of women from multiple sections within the
Medicine Women’s Committee continues to serve as an
Department, all of whom are amazing leaders, scientists, clinicians
important mechanism for networking, mentorship, professional
and educators in their own right.
development and advocacy for the female faculty. The Committee
T h e D O M Wo m e n’s C o m m i t t e e e n j o y e d s e v e r a l s u c c e s s e s i n F Y 15 :
• Developed the Department’s “Women at the Forefront”
biannual newsletter highlighting the accomplishments of
women faculty and trainees
• Collaborated with the Office of Faculty Affairs in providing
opportunities for leadership training and professional
development for women faculty and trainees
• Held two professional development events with guest author
Sara Laschever who presented on “Women Don’t Ask: Personal
Fulfillment, Professional Success, and the Power of Negotiation”
and George Andrews, associate dean at the Booth School of
Business who spoke on “Critical Conversations: How To Speak Up
When The Stakes Are High, Emotions Are Strong and Opinions Differ”
• Featured Arlene Chapman, MD, professor of medicine and chief,
Section of Nephrology as the Women’s Committee’s Grand
Round Speaker for 2015
Please visit medicine.uchicago.edu for a full version of the Department of Medicine 2015 Annual Report,
which includes a detailed list of sponsored research.
Editorial direction by Annette Westerberg
Publication design by Words&Pictures, Inc.
Photography by David Christopher, Dan Dry, Megan Doherty, Ashley Heher, Robert Kozloff, Jean Lachat, Drew Reynolds and Jasmin Shah
74
DEPARTMENT OF MEDICINE
5841 South Maryland Avenue
Chicago, IL 60637
medicine.uchicago.edu

Department of Medicine Annual Report 2015

Transcription

Similar documents

Future Hits Schubas Halloween Show Poster

Religion - VoFotos

City Design Tour

Data Center Mechanical Installation

Advance Tickets: Buy your tickets today!

be money smart!

press kit

Change in Program Plan – Graduate Studies

Tsi-tsi-ki Felix

rIVEr OAKS CENTEr - washington prime group