- PANS National
Transcription
- PANS National
PHARMEDIA "A Publication of Pharmaceutical Association of Nigerian Students (PANS), National Secretariat, University of Lagos." May, 2013 Sugar; the deadly love affair PHARMACY; A profession finding its place Much ado about FASHION The lady; her lover and his football 15 easy ways to cut calories and lose weight PROFESSIONALISM IN PHARMACY; Implementing the vision in a dynamic continuum + Exclusive interviews with Mazi1 Ohuabunwa, Prof. Ogunlana ... 2 3 CONTENT Features: Pharmacy Practice and the Fresh Graduate Pharmacy; a profession finding its place Liposomal Drug Delivery Systems Updates: Margaret Thatcher Medication Adherence Young Pharmacists Group-FIP IPSF Interviews: Mazi Ohuabunwa(Life patron of PANS national) Professor Ogunlana(The first Nigerian dean of the first Faculty of Pharmacy in Nigeria) Insights and Perspec ves: The lady; her lover and his football Professionalism in Pharmacy: Implementing the vision in a dynamic continuum Real Mentor Do you think the heart is the perfect organ of love? Success is an attitude Radioactive students Take Responsibility for your life Pharmacy; a Profession or an Occupation? Health: 15 easy ways to cut calories and lose weight Tuberculosis Live longer with your eyes closed Nutri on: Sugar; the deadly love affair Benefits of drinking water 10 health benefits of A, B, C Entertainment and Fashion: End of the tunnel Who is to blame? Much ado about fashion Funny and interesting facts Sports: The secret to a successful sporting career The 19-year wait Jokes and Poems: Uphill and down dale The Pharmacy Student Remind Yourself My Apology 4 FROM THE EDITOR'S DESK With utmost gratitude to God and also to my editorial board members, I present to you this edition of Pharmedia magazine which will definitely hold you spellbound and will educate, inform and entertain you to the fullest measure as it contains lots of well structured and brilliantly articulated write-ups that are mind blowing. This edition contains several articles on health, sports, insight, features, nutrition, perspectives, fashion, entertainment and exclusive interviews with two carefully selected, impactful and enviable icons in the pharmacy profession namely Pharm. Prof. Sir E.O. Ogunlana (OON, FPSN) who was the first Nigerian dean of the first Faculty of Pharmacy in Nigeria and Mazi Sam Ohuabunwa who is the life patron of PANS national. In this magazine is incorporated a write up on tuberculosis, a fast growing deadly disease with the highest of its occurrences in India, China, South Africa, Nigeria and Indonesia respectively as at 2008; an exposition on success as an attitude; an insight into the secret to a successful sporting career; a revelation of who a real mentor is and then a close look into pharmacy practice and the fresh graduate which was written by a prolific writer and pharmacist, Dr. (Mrs.) Arinola Joda; and then the theme of the magazine being “Professionalism in Pharmacy: Implementing the vision in a dynamic continuum.” All these and other topics are aimed at informing, educating and entertaining you. Keep cool, relax and be sure to get the best even as you peruse each leaflet. A feedback from you will be highly appreciated. Send your comments to [email protected] Olagunju Muyiwa Joshua [email protected] 07033862662 5 PRESIDENT S NOTE Pharmacy profession has evolved over the years to accommodate global changes in scientific innovations, technology, health reforms and societal impact. Despite these inevitable transformations, the need for a proven extent of improvement cannot be overemphasized. The many challenges faced by the profession may have instigated setbacks, both directly and indirectly. However, of the several absurdities, pharmacy profession has obtained sustainable levels of EXCELLENCE. Excellence is a talent or quality which is unusually good and so surpasses ordinary standards. As President, I am delighted at the level of my unperturbed interest as well as the enthusiasm generated by Pharmacy students nationwide that a clear perception of this vision will in no doubt be very helpful in mobilizing our common goal, with the health of the society as our passion. Every accomplishment starts with a decision to try something new, this is a step to achieving EXCELLENCE. It is with gratitude to God, great joy and excitement that I, on behalf of my fellow Executives of PANS National 2012/2013, heads of committees, members of committees and fellow PANSites of this prestigious association extend a very warm and hearty welcome to you all to the 38th Annual National Convention tagged 'EXCELLENCE 2013' in the university of first choice- University of Lagos. We are deeply honored to have you all from far and near across the country. Being a group of pharmacy students with keen interest in promoting improved public health through provision of information, education, networking, and a range of publications and professional activities in the country, the positive impact of this great association PANS on lives in years back cannot be over-emphasized, as we are constantly built up in learning, character and zeal to improve lives and heal the nation sequel to our professional education. We have identified the need to have a common ground and thus have come this far. It is no doubt that the future of pharmacy practice in this nation is bright and it must be realized that whatever hope pharmacy education and pharmacy practice has in controlling its destiny lies with the action or inaction of us Students the future professionals and the frontiers of her course. The theme for this year's convention 'EXCELLENCE ' was borne out of the legacy pharmacy profession stands for, outstanding achievements the profession has encountered, coupled with the fact that the host city has its slogan as “CENTER OF EXCELLENCE”. In our time together there will be unique opportunities and ample time for all delegates present to meet and connect with fellow PANSites, engage in healthy rivalries, network, share ideas and reach a consensus on the way forward for our noble profession all over the country. Excellent speakers have been carefully selected to speak on various fascinating, vibrant, compelling, insightful, inspiring, motivating, and above all provocative topics which I can assure you will be of utmost interest. I hereby oblige all delegates to participate actively and devotedly in making this convention a huge success as we use the knowledge of pharmacy's past to improve her future by anticipating likely problems, improving our problem solving creative abilities and applying efforts to influence the future positively. Permit me to express my profound gratitude first to God, my family especially my Mother whose support has been of utmost importance, my fellow National Executive Council members, the Dean of the Faculty of Pharmacy University of Lagos and to all whose advice and tutelage was instrumental in the success of this administration. I love you all. 6 Awiligwe Arinze President PANS EXECUTIVES 2012/2013 Awiligwe Arinze President Taiwo Olumoroti J. Financial Secretary Adetona Olugbenga Secretary General Abidoye Oriyomi Oloko O. Adejoke Ohere Angela Florence Ass. Secretary General Public Relations Officer Treasurer Chinedum V. Enyinnanya Akinnawo Innocent Student Exchange Officer Regional Editor-in-Chief Zone A Olagunju Muyiwa National Editor-in-chief Obembe Anthony Director of Socials Oskar Nkoli Regional Editor-in-Chief Zone B Gloria Tireng Thomas Amusan Oluwaseun Regional Editor-in-Chief Director of Sports Zone C 7 7 PHARMACY; A profession finding its place The Pharmaceutical Society of Nigeria (PSN) is the oldest professional association in Nigeria; but this fact does not translate to mean that pharmacists have found their rightful place in the health care delivering system in the country. The struggle by Nigerian pharmacists to establish themselves as first class professionals and drug experts has a long history. The challenges we meet today are not very different from those our colleagues in other developed countries faced and are still facing. However, these challenges are further compounded by certain factors that will require our determination and a sense of purpose; knowing that the future is mostly in our hands. Pharmacy is a diverse field. It covers all aspects of drug research, development, manufacture, procurement, storage, distribution, dispensing, counselling and pharmacovigilance. This is in addition to academics and drug regulatory activities. Unfortunately, we are seen as dispensers [pill counters or drug marketers] of drugs. We must reflect on our present status, define where we want to be, identify our difficulties and strategize to achieve our goals. A major problem we face is one of identity. We are yet to know who we are, we tend to underestimate ourselves and this attitude reflects in our practice. The public and other health professionals cannot place us higher than we place ourselves. What are the reasons for this and what can we do about it??? Habits, traditions and perceptions are difficult to change and it has been the misfortune of the Nigerian pharmacist to have had a lowly status at birth. He was born a child of necessity, as an assistant to the colonial medical officers who trained him on all sorts of odd jobs, including dispensing of drugs. Now that he has become a trained professional, it is difficult to change the old perception and he must face opposition and obstacles on his way to claim his rightful position. Neither the medical officer who instructed and bossed him, nor the nurse who saw him carrying out instructions nor the public who knew him as a common dispenser will find it easy to look at him differently. Yet, understanding our beginning will help us understand and tolerate our present and prepare our future. It was during the early years where dispensers were trained on the job that drugs lost their respect. Drugs needed to be in the country and so they were. But they were brought in as mere trade commodities by multinationals like U.A.C. It is no wonder that by the time the first pharmacists were ready to be born, the 8 field had already been prepared for chaos and confrontation, as at that time they were handled by business men. By the time few pharmacists arrived, drugs had reached all areas in the country and big corporations had dominated their trade. The country was overrun with untrained patent medicine vendors, who continued to handle drugs like any other item of commerce and were later joined by other drugs peddlers. The problem created still persists till date. At the hospital level, pharmacists still find it difficult to shed the clock of second class professionals. Other professionals still insist on setting boundaries for us, despite the world wide trends and the arduous trainings we undergo. Some political offices still seem beyond our reach despite the fact that, when given the chance, pharmacists have demonstrated their ability admirably well. Some political office holders and health managers still believe that it is a smar t move to employ a pharmacy technician rather than a pharmacist. Is this a result of a historical perception or is it because of our professional output? In other words, do we make it clear in the way we practice that, indeed, we are the drug expert and we can make a difference in the health team? Pharmacists are battling on many fronts and the odds are mighty, but our armoury is in our hands. We must take our profession seriously. We are not traders in commodities or dispensers of drugs. As drug experts it is our responsibility to provide definite and additional value to dispensing. What makes the difference between a pharmacist and a dispenser or technician is the provision of pharmaceutical care and a continuous acquisition of up to date information that will make us a repositor y of knowledge on drug therapy. It is when we continuously update ourselves that we will be confident to contribute by educating other professionals. Educating is not challenging but expressing consciously and even unconsciously a superior knowledge over theirs. We should be the drug and medication consultants. We should champion the rational use of drugs in our health institutions; after all, pharmaceutical care is the responsible provision of drug therapy in order to achieve set therapeutic goals. Our lack of enthusiasm to claim our position has led to w o r s e n i n g p o l y p h a r m a c y, unjustified proliferation of brands being stocked at the same time, increased cost of prescriptions and similar practices. A lot of our practice remains undocumented, making research impossible. As we strive to reposition ourselves, we should embrace the spirit of team work. 9 People resist change, more so when you want to change an old tradition. The resistance is worse when they feel threatened. However and very importantly, we should learn how to interact with other health professionals and avoid open confrontation. When making our points, we s h o u l d a vo i d a c c u s a t i o n s, offensive statements, arguments and the likes. We are all working for the patient and no sane professional will see a valid point and insist on doing that which is wrong. We should always be well prepared to defend our position, not to “win” our arguments but to convince the other party. We look forward to a near future where the hospital pharmacist will not need to initiate the professional interaction with other health cadres, but rather, be sought after. It is comforting that many hospital pharmacists today have continued their education by acquiring post-graduate qualifications in clinical pharmacy and related fields. The challenges now are to put into practice what knowledge they have acquired; that is one of the ways to reposition the pharmacist, especially the hospital pharmacist, in their rightful place. By MARKSON E.OGITIE Su gar The deadly affair possible cause of obesity; as these drinks do not trigger the same sense of fullness as foods with similar calories; increasing the risk of overeating. Studies show that HIGH FRUCTOSE CORN SYRUP (HFCS); a cheap form of fructose sugar, used by food and drinks manufacturing industries as a sweetener; may increase the risk of developing pancreatic cancer; as well as diabetes ( a metabolic disease due to high blood sugar, and the inability of the pancreas to produce enough insulin) Sugary food consumption can be reduced in the following ways1. Swap sugary drinks for water, low-fat milk or artificially sweetened drinks to reduce calorie intake 2. Try swapping sugary snacks for fruits, nuts, and vegetables 3. Try to half the amount of sugar you put in hot drinks, or cut it out completely 4. Choose canned foods and fruits in natural juice, rather than in syrup or drinks. 5. Rinse the mouth and teeth with water after every consumption of sugary foods and drinks The consumption of sugar and sugar-allied foods has become a basic, inevitable part of our existence. We know how much we love the ice-creams (yeah, yeah), the Red velvet cake (ooooooooooh…!), the biscuits, chocolate cookies, those finger foods (that make you feel like you are in heaven when you taste them), and the juices and drinks. We have this wonderful feeling when we have the sweet taste of sugar in our teas and coffees. There is no better way to enjoy the doughnuts, but to have it coated with sugars (Hmmm, how salivating). However, our love for these sugary foods and drinks can cause a lot of devastating effects on our health, especially if consumed in excess. Basically, sugars are simple carbohydrates that taste sweet. They are of different types, ranging from fructose (sugar from fruits); sucrose (combination of glucose and fructose units from sugar cane); lactose (gotten from milk); amongst others. Based on consumable foods, sugar is classified into those found naturally in fruits and milk (which are fine and don't need to be cut down); and those that are added to the diet. These added sugars can be found in a variety of foods, including confectionery, soft drinks, desserts, and breakfast cereals. Added sugars are a great source of energy, but provide no other nutrients. Sugary foods and drinks pose a threat to dental health, especially if consumed between meals. It has been identified to be a We all love sugar, and we can continue to enjoy sugar if and only if we can be moderate in our consumption. 10 By KENE KINGSLEY By Onyeuma Chioma TUNNEL End of the My name is Amanda Schmidt. 'What a weird name', you might think (never mind, I am still a Nigerian). I am a young mother of 4 lovely kids, 2 boys and 2 girls. I am not of age but the experiences which I have had, have made me 'old' (wiser). I didn't mention that I have a lovely husband by name, Anderson Schmidt (that was how I got the name). I am the second daughter of the 5 children of my parents. I grew up with my mother as my only parent. My dad died of a terrible disease of unknown origin, name and cure despite the huge amount of money spent in the best hospitals to save him. It was strange indeed. If it was now, am positive that with my spiritual and medical knowledge, a panacea could have been discovered. I was only 4 years old then, and didn't know 'was sup'. I remember seeing my dad being placed into a big 'bed' (coffin) with cover which had beautiful flowers all over it. I think I remembered smiling when I saw the flowers placed on dad. I wanted mine too, I guess. Then something strange happened, they closed the “bed” where dad was placed and placed him into 'a big hole' (grave). Dad wasn't moving nor saying anything. I wanted to jump in as they poured sand on the coffin but mum wouldn't let me. They were taking dad from me without letting him say goodbye, so I thought. I ended up eating sand that day as I rolled on the floor. I was so naïve, not knowing what was happening. Few months later, dad's relatives came to our house. I was happy to see them but they were not, as their facial expression was so strong. I was happy because I 11 TUNNEL End of the TUNNEL End of the TUNNEL End of the TUNNEL End of the TUNNEL End of the degree. I was flown to Germany to obtain my PHD on scholarship. I worked for few months in Germany in a big pharmaceutical company owned by 'The Schmidts'. That was how and where I met my lovely husband. I had my wedding in Germany with my mother and siblings and my foster parents (in Jos) in attendance coupled with my husband's lovely family and members of staff. My story begins again; My name is Amanda Okeoma Schmidt. On this opening ceremony of my pharmaceutical company in Nigeria, I stand to read my autobiography to you. I tell you, this is my testimony, that God can raise one from the dungeon and place him at the top. In spite of what you are going through, know for sure that you are not the first and will definitely not be the last. Develop the right attitude towards each situation. Turn to the one who has the power to change your story to glory and follow him with all your heart. God can do all things, just seek him hard. I have heard people say that “anything that can't kill you, will make you stronger”. I don't know if it is true, but I sure know that it would change you big time. What do you think? TUNNEL End of the brother's salary was usually sent to my mum to enable her feed herself, my other siblings and to pay their fees as well. She hated to see us suffer but couldn't help it as the sales she made from her kiosk was meagre. They (my mum and my other siblings) fell ill a few times but God was merciful to spare their lives. My eyes get soaked with tears each time I remember my life history, but I write to share the story so that you might be encouraged. I can't tell you all I faced in those years but I can tell you that it was a hell of an experience for me. I wouldn't want to bore you further with my story but the good news is that my tragic story has turned to glory. My brother has now emerged as the general manager of an ultra-modern multinational company in Lagos. My other siblings are doing wonderfully well in school in their various departments. My mum now owns a shopping plaza which houses a boutique, a super mart and a salon, amongst other stores. I, Amanda Schmidt have always had the passion of becoming a pharmacist. I graduated from the University of Lagos with a first class TUNNEL End of the thought they would give me the usual biscuits they brought each time they came to see dad. I was wrong. This time, they came to take all their 'biscuits' from us. They came with some armed men and I saw them arguing with mum while making away with our stuffs. As mum kept confronting them, they beat her to stupor. At this stage my elder brother took us from the house and hid us till the drama lasted. We came back after they left, and met our house empty. Mum never stopped crying till she slept off. We also had to cry ourselves to sleep as no one was ready to cook for us that day. I still hear mum's cry till date but with great joy in my heart now. Am sure you can tell the rest of the story from here but you can't tell the amount of pain, shame, agony and hunger we felt then. Mum couldn't pay our school fees and feed us at the same time even after selling her jewelries and expensive clothing. She took my elder brother and I to one of her relatives in Jos. I was sent to school by this relative of my mum while my brother worked in her shop as the sales boy, pending when he would secure admission into a higher institution. My TUNNEL End of the 12 MargaretThatcher BY; Nwanya Somutochukwu Sullivan At the announcement of the death of Margaret Thatcher, thousands of Britons gathered at Trafalgar square, London for a celebration. "This party had been planned many years ago" one man said when interviewed. These types of celebrations are common when a dictator leaves the seat of power with notable examples in the cases of Abacha, Mubarak and Gadaffi in Nigeria, Eg ypt and Libya respectively. But the question looms: Was Thatcher a tyrant or a victim of strong leadership? To answer this question, we must understand the fact that in leadership, decisions must be made which regardless of the intent affects people's lives in good or bad ways and a leader cannot always explain the intent these lines of action. Born Margaret Hilda Roberts, she was always known to have a combative personality and this was highlighted by her job application being rejected by a company that labeled her "a headstrong and dangerously self-opinionated individual". The later would rear its head later in her political career when by the year 1990, the last minister still in her cabinet since she had become prime minister in 1979 resigned following many others before him who had done the same thing after disagreements regarding policies with Baroness Thatcher. She first became involved in politics-with the conservation party-while still a student at Oxford University. Rising slowly through the ranks, she became leader of the opposition and the conservation party in 1975. After launching a verbal attack on the Soviet Union, the soviet press gave her the title "Iron lady" which she gladly accepted. In 1979, the conservation party won the general elections by a landslide and Margaret Thatcher became the first female prime minister of the United Kingdom of Great Britain and Nor ther n Ireland. Her domestic policies which included privatisation of 13 government-owned businesses were able to transform Britain from an industrial dependent state. Though there was a stable economy highlighted by low inflation, there were still concerns about the high unemployment in Britain (3 million at the time). She was also quick to bring down 'enemies' of her government, most notably the miners' association that was instrumental in bringing down the government of former Britain prime minister Edward Heath under whom she served as minister of education. Her most controversial decision which lead to 70, 000 - 200, 000 people protesting at Trafalg ar square was the imposition of poll tax (where every adult resident in a building was to pay tax on the building). This was one of the major rationales why the same venue hosted the mass celebration at the news of her death. Though she was able to put an end to hooliganism in footballing stadia in the United Kingdom, she is still regarded as an enemy in footballing circles for putting the blame of the loss of lives of some Liverpool supporters on their fellow supporters in the match involving Liverpool football club and Nottingham forest football club at Hillsborough stadium. Later, investigations and re por ts by the inde pendent Hillsborough Family Support Group (HFSG) found these reports to be untrue blaming the incident on the South Yorkshire police and hinted at a serious police cover up. She lived up to her iron lady sobriquet when Britain went to war with Argentina to regain control of the Falkland Islands and South Georgia in the South American coast. She was prime minister during the darkest days of The Troubles and was instrumental in the management of the crisis. This commitment to effective management of the crisis would come at a very steep price as she narrowly escaped an assassination a t t e m p t o n h e r l i f e by t h e provisional Irish republican army. Margaret Thatcher was also seen as anti-african by some Africans n o t a b l y Ay o Fa l e t i ( P u n c h newspaper: Thursday April 11, 2013 page 24) for taking sides with the apartheid governments of presidents Botha, Verwoerd and De Klerk of South Africa while calling Nelson Mandela "a terrorist" and classifying the African National Congress(ANC) "a terrorist organisation". She however officially condemned the abominable regimes and led calls for the end of racial segregation. Margaret Thatcher never stopped at crushing those who opposed her interests but she was also equally effective in bettering the lives of her fellow Britons even in the most ruthless manner possible. I will leave you to reach your conclusions as well as to whom Baroness Thatcher really was as the popular saying goes thus “beauty lies in the eye of the beholder”. Mazi Ohuabunwa (Life patron of PANS national) An interview with MAZI SAM OHUABUNWA, OFR, FPSN, FPC PHARM, FNIM, FIMN, FNIPR, FIMC; the life patron of PANS national, the former Chairman/CEO of Pfizer West Africa and then, former CEO of Neimeth International Pharmaceuticals Plc. CAN WE MEET YOU SIR? I am Mazi Sam I. Ohuabunwa time, a journalist. Later, I wanted to do Business Management and Administration. Though people around me wanted me to study Medicine since I was leading my class, but I myself didn't have interest in that field. I wanted to do Geology because I lived around where there where Shell people who were involved in exploration, so, my fancy was just going all around without a specific field in mind. I was doing well in both the sciences and the arts. SIR, WAS PHARMACY YOUR ORIGINALLY DESIRED COURSE OF STUDY? I wasn't originally looking into studying Pharmacy. As a matter of fact, I had challenge in deciding on a course to study because nobody was there to guide me. At one time, I wanted to be a lawyer, at another 14 I later thought of doing Medicine but after the war in which I was involved as a Biafran soldier and fought for three years, I lost interest since I had already lost 4 years. So, when we resumed in 1970, I forgot about Medicine because I couldn't afford to spend another 7 years in Medicine after all the already gone years. In the course of looking for a shortcut because my fancy was in Business Administration, just as I was about to fill my form into that, I visited an uncle of mine who was a civil servant. As I was holding my form, he asked for the course I wanted to do, I told him but he asked me whose business I wanted to administer. He then advised me to go for a professional course and then do business out of it. We both then checked the brochure for a professional course which was related to Medicine. That was how I ended up in pharmacy. But as I tell people, God works in very wonderful ways because as I finished pharmacy, an uncle of mine who was well-to-do wanted to set up a business and he told me to do business with him. I then requested that he should allow me do apprenticeship for about 3 years so that I could know how the business was really done. I therefore, worked with Pfizer though I also did Business Administration to be more equipped for the task. WHAT DO YOU HAVE TO SAY ABOUT PHARMACY PROFESSION, THE STATUS QUO AND ITS FUTURE IN NIGERIA? Pharmacy profession is a profession that has been largely misunderstood probably from the historical development of the profession. It is a profession that so many people are interested in but not everybody is ready to go through the steps involved; that is why we seem to have a lot of people who are practising something that looks like the profession but are not qualified so to do since so many people see it as an alternative opportunity to be employed especially in the general practice area (community pharmacy practice). For all intents and purposes, general practice is where pharmacy practice seems to have an image but pharmacy is much more than that. The other areas of professional practice where it is difficult to have pretenders are hospital and industrial pharmacy. These areas need to come up in the image of the profession. I believe PCN and PSN are working hard to ensure that unqualified people who are practising the profession are put to order. The profession to me has a future. The evolution in the way we are moving from being product-centric to being patient oriented will also help in crossing a line between the business side of the profession and the technical side. The business side seems to overwhelm the technical side but, if we are able to go through the clinical pharmacy orientation, then the technical side will come up, and the profession can then stand out more distinctively and play its complementary role in the healthcare team. HOW CAN WE THEN ENCOURAGE PHARMACY STUDENTS AND YOUNG PHARMACISTS TO GO INTO THE TECHNICAL SECTION OF THE PROFESSION ASIDE FROM THE COMMUNITY PRACTICE AND THE INDIVIDUAL ASPECT? Well, the encouragement comes largely from making those areas much more attractive in terms of remuneration. This is because the business side is attractive since you can decide to set up your own business so far you have the money. But as a clinical pharmacist, you have to work for a health system. You are therefore going to depend more or less on some people for employment and other things. There should therefore be remuneration and compensation to make those areas attractive. There is need for us to also go into research and development which is a subset of Industrial Pharmacy which is an area where we are not going to compete with anybody. No other healthcare scientist or professional has that knowledge which a pharmacist has when it comes to the area of research and development and production of new drugs. SIR, WHAT IS YOUR VIEW ABOUT PHARM.D. IN NIGERIA? I don't think that the era of B. Pharm. has passed. My own take is that people should have options. For instance, people who want to go into Community Pharmacy, or business can do 5years and move on. It depends on your interest. Then those who want to be patient oriented, who want to go into the key professional technical areas can go for Pharm. D. We have two parallel options that anybody can take. That is the way I feel it should be. A WORD FOR PANSITES SIR. You should know that you are in a noble profession. Seek God and do your best. Endeavor to make the profession proud. 15 Professionalism in Pharmacy: Implementing The Vision In A Dynamic Continuum Interest in Professionalism has grown in recent years. The many reports of the unethical, illegal or u n p r o f e s s i o n a l b e h av i o r o f Pharmacists, Medical Practitioners and officials in large corporate organizations have played no small part in why so much attention is being paid to the issue. Restoring public trust particularly in Pharmacy is really what lies at the hear t of attempts to define, describe, measure and assess professionalism in the Pharmacy practice and other healthcare professions at large. My vision for pharmacy is that we would build a profession that is virile, that is productive, that is fruitful, a profession that will become a benchmark in the comity of decent professions. Pharmacy is a profession that will be in our lifetime in this land. It is a profession that will throw out some of the very best in the larger society; Leaders that will bring to the fore exemplary leadership qualities. What separates a pharmacist from a worker at Mr Biggs? It is simple: pharmacists are professionals. W hat does it mean to be a professional? It means that we are members of a group and that we declare, in a public way, that we promise to act in certain ways towards the society. We have made a “promise” to act in a manner that benefits the society. We have a code of ethics and standards by which we are judged. We have a “duty”, not only to the society, but to our profession. We are obligated to control our own profession. We have a duty to our profession to keep our members focused on their ethical and social requirements. This means that pharmacists should not only act like professionals, but be professionals. “Pharmacy professionals will feel empowered to use the word “no” when faced with undignified, unprofessional, dangerous, dishonest, insulting or offensive situations.” We have a duty to patients and the society at large. If we see professionalism being compromised, then it is up to us to do something about it. To be ef f ective, we n eed a stro n g professional bond. The Pharmaceutical Society of Nigeria PSN alongside the Pharmacists Council of Nigeria has in years past fostered this bond. In essence, we are obligated to our profession to have a strong professional organization. And, that 16 organization must be based on pharmacies professional ethics and social responsibility. It should be like a “rudder” on a ship to guide the profession toward greater professionalism. A Continuum is a link between two things, or a continuous series of things, that blend into each other so gradually and seamlessly that it is impossible to say where one becomes the next A person is said to be Dynamic if he/she is full of energy, enthusiasm, and a sense of purpose and able both to get things going and to get things done In a country as dynamic as Nigeria, a continuum of global trends, disharmony in the curriculum of the underg raduate Phar macy training, delayed nationwide Phar m. D implementation, unprofessionalism in practice as harbored by some and so on, has a lasting solution. The future of Pharmacy lies solely on the input to upcoming professionals. Implementing the Vision in this dynamic continuum is a derivative of the preparedness of Pharmacy undergraduates. Are they at the same pace as the world out there? Comparisons aside, will a Pharm. D equipment of these dynamic young professionals not instigate better health care delivery in our society? Picture a drug custodian and master health care giant with the knowledge of Pharmacovigilance, Pharmacoeconomics, Pharmacopsycology, Public health e.t.c. with an all-round patient care orientation. There is an overall improved patient outcome with a Pharm. D program in all schools of Pharmacy. This is the catalyst for implementing this vision. Education is a key factor in any profession. All professions strive for excellence in their educational requirements. T his urg es phar macists to strive for professionalism in their workplace through constant learning. Every profession has a right of pragmatic upgrade especially in education. Pharmacy education in Nigeria needs much attention especially on curriculum review and Pharm. D program in all schools of Pharmacy. The goal of pharmacy education consists of preparing pharmacy students with the appropriate skills, attitudes, knowledge, and values to render them competent professionals. The core of the pharmacy curriculum has been based on basic science and clinical knowledge combined with pharmaceutical dispensing and communication skills. The adoption of the doctor of pharmacy (Pharm. D) degree as the first professional degree heightened expectations of student perfor mance in professional programs as confirmed in Ghana, Sierra Leone, the United States and the United Kingdom. Pharmacists are obliged to refuse to lower their professional standards, no matter the pressure of their jobs. Not only do we have a duty to refuse to lower our professional standards, we have a duty to promote those standards. All pharmacists will be faced with pressure on the job. They will be faced with less than a professional work place. But, the job does not define the phar macist. The pharmacist defines the job. All jobs within all professions face the dual role of being a professional and making money. Despite the money component, a pharmacist is ethically and professionally obligated to do things in the best benefit of the patient. Pharmacists have taken an oath and they have made a promise to the society. The only way that 17 pharmacists can be professionals is to uphold their promise to the society- optimum health care delivery. When pharmacists act as professionals, the society will recognize them as professionals. How does a pharmacist act as a professional? By putting the interests of the patient first! By Awiligwe Arinze O. 15 A Easy Ways To Cut Calories and Lose Weight nyone who ever tried to lose weight knows it takes a lot of effort and dedication. Fortunately, it's easier than you think. If you burn more calories than you eat, you lose weight. By cutting about 500 calories a day, you can enhance your weight loss efforts and achieve your weight loss goals faster. because 3,500 calories equals to 1 pound of fat, you need to burn 3,500 calories more than you take in to lose one pound. So, if you cut 500 calories from your diet every day, you will lose 1 pound a week (500 calories x 7 days = 3,500 calories). Calories are the energy in food. Your body has a constant demand for energy and uses calories from food to keep functional. These calories will remain stored in the body as fat unless you use them, either by reducing your calorie intake or by increasing physical activity. Cutting calories can be easy. It's a matter of making a simple substitution over the course of a day. Here are some easy ways to cut calories, which in turn will help you lose weight: 2. Downsize on Desserts: Cutting 1. Drink Green Tea: If you can not abstain from drinking tea in the morning, go for green tea. Green tea can burn up to 70 calories per day because it increases your metabolism. Since there is no need to add cream or sugar, it is the best way to start your day. 3. Eat Fresh Fruits: Choose fresh fruit instead of fruit juice. Fruit juices contain lots of sugar to sweeten them. A medium-sized orange has 60 calories, while a cup of orange juice contains 120 calories. In addition, fresh fruit has more fiber, which helps facilitate digestion. calories does not mean saying no to all dessert. You certainly can have them but in a very small proportion. Small steps such as skipping chocolate topping or avoiding cream can go a long way! 4 . Limit Alcohol intake: Most alcoholic beverages are high in calorie. These include beer, wine, and cocktails. In addition, alcoholic drinks have very little or even no nutritional benefit. If you must to take alcohol, choose lower-calorie one. For example, order a light beer instead of regular beer. 18 5. Choose Water over Soft Drinks: Changing the soft drinks with water can save you hundreds of calories per day. If you can not give up on soft drinks then try switching to diet soda drinks. Choosing the coconut water over the fruit juice can also help because the coconut water is low in calories and high in vitamins and minerals 6. Increase Protein intake: High protein can help keep fat away. Protein requires a complex procedure to be converted into energy and it also can make you feel full. is not large enough to accommodate the mound of food buildup. 11. Avoid Starchy foods: Starchy foods like potatoes tend to have more calories, so, it is better to avoid or replace them with peas or other beans such as chickpeas and kidney beans which are rich in fiber and vitamins. 12. Select Whole Grain: If possible, eat whole wheat grain bread and whole wheat pasta instead of white grain. Whole wheat gives you fewer calories and more nutrients. They are also rich in fiber andiron 7. Use less oil when cooking: Instead of bathing your food with oil, try using a tablespoon of oil at a lower heat setting. Spread less butter on your bread and avoid putting it in your food. Prefer healthy cooking oils like flaxseed oil, olive oil,etc which provide fewer calories and more Omega-3 fatty acids. 8. Eat more Vegetables: Vegetables like broccoli, carrot, are rich in fiber, which is not only good for your digestive system, but are also good to give your stomach a sense of fullness so you eat less. 9. Reduce Portion size: You do not have to eat 3 large meals a day. Instead, you can reduce portion sizes and have 4-5 small meals a day. This keeps your metabolism busy throughout the day. If you eat one plate of rice, cut into a half. 10. Go for Smaller plates: Changing the size of your plate into smaller ones. The bigger the plate you have, the more likely you eat more. So, switch it to a smaller one. It is easier to resist the temptation to fill the plate if the plate 13. Eat at Home: We tend to get more calories when eating out. When you eat at home, you can control how to prepare it and the portion sizes. 14. When Eating out, Order smartly: When eating at a restaurant, order an appetizer as your main dish. If you 're still hungry, order a salad but without mayonnaise based dressing. Also, not a large amount of pouring salad dressing, you just dip the fork into the dressing before taking a salad. When ordering pizza, choose thin crust base with less of fat and more vegetables. 15. Read Food Labels: Be sure to check the Nutrition Facts panel and the number of calories per serving on the packages. Do not just check the amount per 1oz or per 100g but the amount of the whole package and think about how much you normally would eat. Then decide whether to leave it on the shelves or take it home to add to your waistline. Cutting calories does not have to be painful. By following the tips above you should be able to cut calories and lose weight easily. 19 The Lady, Her Lover & his Football “The most psychological part of a man's attachment for football is the extent to which a game affects...” 20 Some relationships tend to go through their seasonal toll directly proportional to the football season. Now, this title has caught your attention for a number of reasons. Some ladies expect that I'd be expressing their predicament and the gents would probably check my gender first. Do confirm that I'm not Steve Harris before deciding to read on. In “the lady, her lover and his football relationships”, there are basically three types of ladies. 1. The indifferent lady 2.The understanding lady, and 3.The Lady that had to get used to it. A man's love for football is an in-depth relationship some ladies need help understanding. At first, I sure did not get what was so intriguing or pleasurable about kicking a ball, but with a little help, I've come to understand that for men, football is drama while women love Nollywood, Hollywood or Bollywood in this part of the world. Men see football as live unpredictable drama, breath taking, fascinating, suspense-filled, boring, invigorating, exciting, frustrating, exhilarating, action packed; full of heroes & villains, controversy, skills, cynicism, violence, trickery, bravery, cowardice, joy and misery all in just 90 minutes. Why a man has the capacity to make cogent plans to sit for hours to watch a football game when he won't sit for more than 10 to 15 minutes for anything emotional except money matters, are due to the following reasons: 1. Male bonding; social reasons and something to talk about...well...other than ladies, money and politics; 2. Entertainment; 3. An avenue for venting male aggressiveness; 4. Escaping the ladies in their lives and some responsibilities; The most psychological part of a man's attachment for football is the extent to which a game affects his mood as it identifies some amount of his happiness based on how well his team plays and then remains in a horrendous mood when his team loses especially a penalty. I have to admire such responsibility as I for one am too sensitive to have my happiness jeopardized by such unpredictable drama; the suspense is enough for me. Call it cowardice if u will; simply accord it the same way a lady is expected behind the wheel when the driving goes wrong... ...but then I'm cool with the mantra; "join the winning team..." The mood is worse off, of course, for those who dare make bets. Now, onto the more important aspect of this whole idea; how ladies on the receiving end get through this football toll. It isn't physical enough for them to trail, clap hands at, and chant "ooo ooo ooo...boyfriend snatcher...or what not" (Thumbs down...by the way...) Still, a few tips will keep us from feeling left out, which are: 1.Move beyond the "football or me" ultimatum because it'll either push him farther away or breed resentment, if ever you succeed in getting him to choose you. 2. Find your own football-time distraction; you mustn't do the football thing together. 3. Schedule "together-time" outside when the leagues are playing. 4.When you eventually get to schedule a nonfootball time, avoid distractions; especially complaints about his football attachment. 5. Try to give football a chance. Granted...It's rare these days to find ladies who aren't into sports, yet those of us that aren't, before getting mad at something that doesn't have the capacity to wear heels should try watching at least part of the game to find out what your partner enjoys about it. I prefer to find out who has scored or when the referee's bitching, just for the kicks of having a football convoy. Well, I may have been as liberal as possible but personally, I'd rather have someone who'd damn his football once in a while to take my call when I'm tired of being lady number two. Wishing you a wonderful football season! By Nkoli Os'kar 21 Pharmacy Practice and the fresh pharmacy graduate Pharm. (Mrs) Arinola Joda PhD., MAW Someone described life as “what happens to you while you are making other plans”. Life is definitely different, more challenging out of school than during school when lives and time are more or less planned and usually pretty predictable. When end of school is approaching, feelings of insecurity, quiet desperation and envy may set in. You may find yourselves asking one another of plans after school, hoping to find the magic way of planning your own life. In school, you have learnt that there are various practice areas in Pharmacy to choose from. By now some of you already have an idea of what you want to do after school. Some of you (and I don’t mean just the graduating students) know they want to be in Community Pharmacy, others in the hospital or even consultancy practice. In the same way, some already know they want to come into academia, or know they want to further their education either in pharmacy or in business. Some others know that their first priority is to travel out of the country. This is, however, not the topic before us. There are many areas of pharmacy that the fresh graduate can practice and excel in. To refresh our memories we have about four core practice areas in pharmacy which include community practice, industrial practice, hospital practice & administrative pharmacy and academic practice. Each of these core areas can be further broken down into other smaller parts. Let me take each of these parts one by one in brief. Community Practice: Practitioners in this area belong to the Association of Community Pharmacists of Nigeria (ACPN), the technical group under the Pharmaceutical Society of Nigeria (PSN) that coordinates their affairs for the national body. 22 Community Pharmacists are one of the most important groups of Pharmacists because they form the bulk of the Pharmacists in the country. About 60 to 70% of Pharmacists in Nigeria belong to ACPN. Pharmacists that own community pharmacies, Pharmacists superintending community pharmacies as well as Pharmacists that work as fulltime staff in community pharmacies all must register with the ACPN. Young Pharmacists intending to practice in this area should work with well-established and well run community pharmacies to learn the ropes. Apprenticeship is a very good idea for community Pharmacists because it will open your eyes to potential problems that you may encounter as well as tools to use to solve these problems. It is not a wise move if fresh graduates go ahead and establish their community practices without this period of training because even if all the resources you need are available (the location analysis is good, the money is available for renovations and stocking and the staff to be employed are there) much time and money will be wasted on things that should not have been embarked upon if you had known. Like the PSN, ACPN has a national body as well as branches in each state of the federation including Abuja. Industrial Practice: The Pharmaceutical industry is the most diverse group in Pharmacy. It comprises such groups as Marketers, Production Pharmacists, other Pharmacists in the drug and foods industries as well as Pharmacists in agrochemicals, publishing and consulting segments. Pharmacists in the industry pride themselves on being the engine room of the profession. They produce the drugs, ensure its safety and coordinate and organize systems including publications. NAIP has a national body and is currently organizing zonal representation to further enhance its activities. Young Pharmacists with a vision for the industry will need a large dose of patience as one of his/her attributes. An active PANS representative may find it easier to link up with the industry gurus through fund raising activities carried out while in school. Usually, marketing is the place to start though some may plug into the production end of industry as soon as possible. Production is one area where there always seems to be a need for Pharmacists in industry so this is a good route to enter into the industry although it may take a while before you can cross over to other areas but it is not impossible. Hospital Practice: Hospital Pharmacy practice is one area where Pharmacists need to make the most impact. This is because pharmacy practice is assessed through the hospital. Hospitals still using the 2x2 windows are not doing the profession any good and Pharmacists working in such places should make consistent moves for a change to the new paradigm of the practice where 23 pharmaceutical care is the watchword and patient counseling is an absolute essential and adequate areas for this to take place are a sine qua non. Most young Pharmacists have two opportunities to work in the hospital i.e. during internship (because internship in the hospital seems to pay the highest in terms of takehome pay and also in convenience) and during the youth service programme (because Pharmacists as well as other medical persons are usually posted to rural/sub-urban hospitals where the need for their services are great and never-ending). Hospital practice can be both satisfying and rewarding if the practitioners in the hospital embrace pharmaceutical care. Young Pharmacists of today have a greater understanding of the concept of pharmaceutical care than many older Pharmacists and they must remember that in trying to get the status quo changed, diplomacy is the key. You cannot compel someone to change a system when he has not seen practically the benefit of the new system so there is a need to take things slow, start small to demonstrate benefit and then push some more. For the young Pharmacist with a vision for Hospital practice, realize that even though you may be getting a better salary than your counterparts in other practice areas in the beginning you must not rest on your oars and become lazy intellectually. Keep yourself sharp and in touch with current happenings. It will be easier done if you can take a locum job in the evenings in a community pharmacy not too far from where you live. This will help you to stay current. Most Administrative Pharmacists are found in the Hospitals which is why they are joined together as an interest group under the PSN. The National Association of Hospital and Administrative Pharmacists (NAHAP) have both a national body and state branches. Administrative Pharmacists are Chief Pharmacists, Directors and Assistant Directors of Pharmaceutical Services etc. These have grown through the ranks in the hospital and so do not carry out direct pharmacy services anymore. They are also found in the Ministries of health whether at federal, state or local government levels. They are directly involved with setting up policies that will make the profession a more comfortable and profitable one for all practitioners. Unfortunately, because their numbers are relatively few compared to other medical personnel, the future of the profession is largely reduced to a game of numbers with the majority deciding the vote most of the time. So, more Pharmacists need to be employed in these places to enable us move further faster. Academic Practice: The Academia is the most restricted area of Pharmacy practice, in my opinion. Not everyone can apply at the same time and not everyone can be taken at the same time. Factors that favored employment of academic Pharmacists in one season may no longer be the factor in the next and so many things are factored in before one can get employed as an academic Pharmacist. A positive development, however, is the increase in the number of universities offering Pharmacy as a course of study as well as establishment of private and state universities also beginning to offer the course. Academic pharmacy requires not just Pharmacists that like to read and who passed well while in school but rather a Pharmacist that likes to pass on knowledge and who is willing to learn how to do so and how to improve in doing so. Academic pharmacy, just like any other practice area requires people that have a vision for teaching and research. There's a common phrase that cannot be missed in academia and that is “Publish or Perish”. As an academic Pharmacist you will not only learn new things, teach new things you must also write and so those people that have already developed their writing ability to a good extent have a much shorter road to walk in learning to publish than those that have not. Young Pharmacists intending to stay in academia need to continue on the education ladder as soon as possible, quickly following up the bachelor's degree with a Masters as well as a Doctorate as soon as they can. While working on these degrees, the young Pharmacist should also work on publishing some articles whether from old projects/ research e.g. undergraduate degree project work or Masters Degree project, or publish articles from literature surveys or reviews. Academic Pharmacy can be challenging or humdrum depending on how you choose to play it and depending on the other lecturers in your department and/or faculty. The National Association of Pharmacists in Academia (NAPA) is the interest group academic Pharmacists belong to and branches are only found in states where Pharmacy is offered as a course of study in the university. A national body coordinates the activities centrally. Though other areas exist including pharmacy journalism, Pharmacists in the Military and other paramilitary agencies, they would need to relate through one of the afore-mentioned areas. Aside from Pharmacy practice, Pharmacists can function effectively in other areas such as telecommunications and banking, etc. (because the pharmacy industry trains its marketers to be able to market just about any product). Pharmacists are thoroughbred professionals who can hold their own in any industry and segment of society. The mix of pharmacy and medical courses, management courses, marketing and even forensic pharmacy provides Pharmacists the basic tools needed to function as a manager, accounting officer, administrator, marketer, counselor, adviser as well as the main Pharmacy practice that he is trained for. Therefore, I enjoin all young pharmacists to hold their head up high. Add to all the things you have learnt the 24 n o i t E a c C i d N e A M R E H D A of . n tio plan r o l p ent a t i A v treatm the Iho Chike Sydney The World Health Organization (WHO) defined health as "a state of complete physical, mental, and social well-being and not merely the absence of disease or infirmity. Health is the level of functional or metabolic efficiency of a living being. In humans, it is the general condition of a person's mind and body, usually meaning to be free from illness, injury or pain. This sound state of the human physiology can be butt-in by diseases, mechanical injury, cerebro-vascular accidents, etc. The presence of these shortcomings necessitates the temporary or many a time permanent dependence on medications to bring the anomalous human physiology to/near normalcy. Medication on the other hand is the treatment of an ailment with any chemotherapeutic agent that is prescribed by the right health care provider and administered accordingly. Medications play an important role in health care and they work best when taken correctly. Medication Adherence...? "Medication adherence" (or compliance with) means taking the right amount of your medication - no more, no less - at the right time, and in the right way for as long as your health care provider suggests. Adherence to a medication regimen is the extent to which patients take medications as prescribed by their health care providers. The word “adherence” is preferred by some health care providers because “compliance” suggests that the patient is passively following the doctor's orders and that the treatment plan is not based on a therapeutic alliance or contract established between the patient and the physician. Both terms are imperfect and uninformative descriptions of medication-taking behaviour. Unfortunately, applying these terms to patients who do not consume every pill at the desired time can stigmatize these patients in their future relationships with health care providers. The languages used to describe how patients take their medications need to be reassessed, but these terms are still commonly used. Regardless of which word is preferred, it is clear that the full benefit of the many effective medications that are available will be achieved only if patients follow prescribed treatment regimens reasonably closely. The rate of adherence for individual patient is usually reported as the percentage of the 25 prescribed dose of the medication actually taken by the patient over a specified period. Some investigators have further refined the definition of adherence to include data on dose taking (taking the prescribed number of pills each day) and the timing of doses (taking pills within a prescribed period). Terrence Blaschke and Lars Osterberg, in their collectively reviewed article'Adherence to medication' said that adherence rates are typically higher among patients with acute conditions, as compared with those with chronic conditions. Persistence among patients with chronic conditions is disappointingly low, dropping most dramatically after the first six months of therapy. Whys and Wherefores for good adherence to medication If you don't take your medications as recommended, they will elicit no therapeutic effect as they should have done. Everett Koop said, “Drugs don't work in patients who don't take them”. In addition, taking your medications incorrectly can adversely affect your health. Take the dose that the doctor said is just right for you. Poor adherence to medication regimens accounts for § Substantial worsening of disease. In the case of a microbial infection, development of resistance by the micro-organism to the antimicrobial agent ensues. § Increased health care costs and § Death. Given the magnitude and importance of poor adherence to medication regimens, the World Health Organization has published an evidence-based guide for clinicians, health care managers, and policymakers to improve strategies of medication adherence ( Sabate E. Adherence to long-term therapies: evidence for action. Geneva: World Health Organization, 2003). Evaluation of medication adherence Adherence to medication regimens has been monitored since the time of Hippocrates, when the effects of various portions were recorded with notations of whether the patient had taken them or not. Even today, patients' self-reports can simply and effectively measure adherence. The methods available for measuring adherence can be broken down into two (2) categories: Ø Direct methods of measurement and, Ø Indirect methods of measurement Each method has its advantages and disadvantages, and no method is considered the gold standard. Direct methods of measurement of adherence include; measurement of concentrations of a drug or its metabolite in blood or urine, and detection or measurement in blood of a biologic marker added to the drug formulation. These methods present in themselves herculean tasks to the health care providers, also, they are very expensive and predisposed to distortion by the patients. Indirect methods of measurement of adherence include asking the patient about how easy it is for him or her to take the prescribed medication, assessing clinical response, performing pill counts, ascertaining rates of refilling prescriptions, collecting patient questionnaires, using electronic medication monitors, measuring physiologic markers, asking the patient to keep a medication diary, and assessing children's adherence by seeking the help of a caregiver, school nurse, or teacher. Questioning the patient (or using a questionnaire), patient diaries, and assessment of clinical response are all methods that are relatively easy to use, but questioning the patient can be susceptible to misrepresentation and tends to result in the health care provider overestimating the patient's adherence. Likewise, pill counting is not assumed a good measure of adherence because medicines can be switched between containers and also, it generates no information on the administration of the 'collected' medicine, such as dose timing and drug holidays (i.e., omission of medication on three or more sequential days), both of which may be important in determining clinical outcomes. Electronic monitors capable of recording and stamping the time of opening bottles, dispensing drops (as in the case of glaucoma), or activating a canister (as in the case of asthma) on multiple occasions have been used for approximately 30 years(Lars Osterberg, M.D.,et al: Adherence to medication). These devices provide precise and detailed insights into patients' behaviour in taking medication, but they are still indirect methods of measuring adherence; they do not document whether the patient actually ingested the correct drug or correct dose. Patients may open a container and not take the medication, take the wrong amount of medication, take the right amount of medication and probably flush it out in the water closet or invalidate the data by placing the medication into another container or taking multiple doses out of the container at the same time. Sticking points to adherence Poor adherence should always be considered when a patient's condition is not responding to therapy. Research on adherence has typically focused on the barriers patients face in taking their medications. Common barriers to adherence are under the patient's control, so that attention to them is a necessary and important step in improving adherence. According to Cramer J. in one of his works titled “Patient compliance in medical practice and clinical trials”, he stated that in responses to a questionnaire, typical reasons cited by patients for not taking their medications included forgetfulness (30 percent), other priorities (16 percent), decision to omit doses (11 percent), lack of 26 information (9 percent), and emotional factors (7 percent); 27 percent of the respondents did not provide a reason for poor adherence to a regimen. Physicians contribute to patients' poor adherence by prescribing complex regimens, failing to explain the benefits and side effects of a medication adequately, not giving consideration to the patient's lifestyle or the cost of the medications, and having poor therapeutic relationships with their patients. Also health care systems can create sticking points to adherence by limiting access to health care, using a restricted formulary, switching to a different formulary, and having prohibitively high costs for drugs. Mediation to poor adherence Methods that can be used to improve adherence can be grouped into four (4) general categories: v Patient education; v Improved dosing schedules; v Increased hours when the clinic is open (including evening hours), and therefore shorter wait times and v Improved communication between physicians and patients. Educational interventions involving patients, their family members, or both can be effective in improving adherence. Learning about your medications can help you stick to your medication schedule. Strategies to improve dosing schedules include the use of pillboxes to organize daily doses, simplifying the regimen to daily dosing if possible, and cues to remind patients to take medications. Clinic scheduling strategies to improve adherence include making follow-up visits convenient and efficient for the patient. Delays in seeing patients and problems with transportation can undermine a patient's willingness to comply with a medication regimen and to keep follow-up appointments. Interventions that enlist ancillary health care providers such as pharmacists, behavioural specialists, and nursing staff can improve adherence. Finally, enhancing communication between the physician, pharmacist and the patient is a key and effective strategy in boosting the patient's ability to follow a medication regimen. In conclusion, most methods of improving adherence have involved combination of behavioural interventions and reinforcements in addition to increasing the convenience of care, providing educational information about the patient's condition and the treatment, and other forms of supervision or attention. If you don't always take your medication exactly as your health care provider has prescribed, you aren't alone. It's easy to get off schedule, especially if you are taking many different medications each day. Talk to your pharmacist to learn about which programs may be right for you. Bear in mind that the micro-organisms (in cases of infection) keep to their slogan – “what does not kill you makes you stronger”. If the medication is not strictly adhered to, they tend to develop into resistant strains which invariably predispose the physiology of man to end stage effects. Remember, a healthy attitude is contagious but don't wait to catch it from others. Be a carrier. -Tom Stoppard “Delays in seeing patients and problems with transportation can undermine a patient's willingness to comply with a medication regimen and to keep follow-up appointments.” Continued from Pg 24 character and positive appearance needed of a professional and I can assure you that you would have no limits. Never dress in a way that clients will need to ask if you are the Pharmacist. Always be well turned out. Have integrity when people are there or when they are not. Treat people well as they approach you for help, advice, medicines or support. Provide unfailing care to all your clients. Be courteous with superiors, colleagues and those behind you. Be true to yourself and your God. Then you will find yourself excelling beyond your wildest expectations. 27 THE Real Benjamin Franklin said, “Tell me and I forget, teach me and I may remember, involve me and I learn”. This in a nutshell tells me that for me to learn, I need to be involved in a particular process or activity during which I might need to be guided or encouraged by someone who is more experienced than I, to put me through in order to achieve or attain a height which may be stressful or might take time for me alone to achieve. The more experienced individual who is in this with me is thus my “Mentor”. “A mentor is someone who sees more talent and ability within you, than you see in yourself, and helps bring it out of you” -Bob Proctor. Mentorship is a personal developmental relationship in which a more experienced or knowledgeable person helps to guide a less experienced or less knowledgeable person. However, true mentoring is more than just answering occasional questions or providing ad-hoc help. It is about an ongoing relationship of learning, dialogue, and challenge. A mentor has the role of passing information, advice and techniques to another to aid them in finding the right space for them. If you have a mentor and you do not hate him/her at one point or another, you have the wrong mentor because he/she is expected to be completely honest with you. This will be helpful, wonderful, awful, devastating, rewarding and everything else that is good and possibly everything else that seems bad. A mentor should be someone who listens and understands. Listening is a skill and there are ways to sharpen it, to fully understand what someone is saying, what he/she means and how he/she feels. A skilled mentor even follows up every inconsistency in a mentee's speech to understand the person's feelings in anticipation of whatever event is on-coming. A mentor should also be one who plans and thinks about how to work through a challenging or confusing situation. Along with helping another person think through specific steps for working through such situation, a skilled mentor would also think about ways of helping the person clarify short term and long term goals, how today's actions move him/her either towards or away from achieving these goals, and the specific kinds of support and resources that will be required for the person to successfully work through each step of the action plan to completion. 28 Along with listening skills and knowing how to assist others in setting and achieving goals, additional areas for the mentor to develop paraprofessional skill and expertise would include: facilitating a professional working relationship protecting privacy, maintaining confidentiality and establishing appropriate boundaries; establishing trust, rapport, and open communication; being fully aware of how actions are demonstrations of our values; understanding and modelling the tools of reflection and self evaluation; working to understand and be sensitive to the impact of diversity and culture; applying principles, values, and ethics to evaluating the impact of mentoring; and synthesizing experience and training into one's own emerging mentoring style. A mentor is also a person who has learnt through success as well as challenges. He/she realizes that respect is always earned; never something simply expected or demanded. He/she accepts other's inhumanity; realizing that to err is human and to forgive is divine. Properties that make a good mentor Mentoring does not necessarily need/require special skills but mentors are simply people who have the qualities of good role models. They do the following; · Mentors listen: They give mentees their full attention and maintain eye contact. · Mentors are practical: They give insights about keeping on task and setting goals and priorities. · Mentors guide: They help to find direction. · Mentors educate: They educate about life and their own careers. · Mentors provide insights: They use their personal experience to help their mentees avoid mistakes and learn from good decisions. · Mentors are supportive: They continue to encourage their mentees to help them learn and improve no matter how painful the mentee's experience. · Mentors are accessible: They are available as a resource and a sounding board. · Mentors are specific: They give specific advice on what was done well or could be corrected, also what was achieved and the benefits of various actions. · Mentors criticize constructively: They print out areas that need improvements, always focusing on the mentee's behaviors, never his/her character. · Mentors care: They care about their mentees' progress wherever and in career planning, as well as their personal development. 29 Continued on pg. 33 P I C T U R E PSN National Conference, OGUN 2012 in Abeokuta Ogun State PANSites in full representation PANSites with Professor Dora Akunyili Group Picture of PANSites with CEO Rodot Nig Ltd Remi Adeseun, and Dr Arinola Joda PANSites with Pharm Inter-school Quiz competition during the Young Pharmacists Forum Access Control during Registration of delegates PANSites arriving in grand style (Mrs) Bukky George Frm Left - Right PANS Uniport President, PANS Unijos President and PANS national President Unijos PANSites in Olumo rock Olumo rock things CEO Health Plus Pharmacy PANSites in Abeokuta PANS National Convention Unijos 2012 Marvellous and Funkiest PANSite 2012 @ the wildlife park PANS Unilag representatives PANSites with representatives of Youth Ministry Plateau State PANS National Secretary General and Unijos PANSites 30 Unilag and Unijos PANSites PANS Unilag President Azeez Owolabi and Ene P R O F I L E PANS National Excos in Action Frm L-R Golden Professor of Pharmacognosy, Professor Olukemi Odukoya and PANS National President Frm L-R PANS National President and PANS National Secetary general Inauguration Ceremony of PSN National President Pharm Olumide Akintayo PANS representatives at Fidson Healthcare PLC PANS National Excos with Pharm Sir Mazi S.I. Ohuabunwa FPSN Representatives gifts presentation Deliberations at 1st PANS NEC Meeting PANS representatives with the GM Distribution and Sales, MTN Richard Iweanoge Opening ceremony of the PSN national E-Library PANSites in academic drills PANS-UNN Dinner party Student carrying out analysis in physical pharmaceutical lab Students using the HPLC PANS report in health campaign 31 Do you think the Heart is the PERFECT Organ of LOVE? Have you ever wondered why the heart for so long has been in use as the organ of the body that represents Love? This I have always been doing since I was young even until now. I used to believe that since reasoning is done by the brain and that what we call “mind” lies there, then the brain without being sentimental should have been the appropriate organ to be called the “organ of love”. Scientifically now, the brain controls the release of hormones that make you feel the way you do whenever you are with that person you love. Plato, an influential Greek philosopher, once said that love is a serious mental disease. I do wonder why people have to feel the way they do whenever it comes to love. These feelings of inexplicable moodiness when love is far away and that of excitement together with almost uncontrollable tachycardia when love is near don't just come unless the brain causes the release of hor mones like oxytocin, testosterone and estrogen into the circulatory system which brings about these emotions. Love is so wonderful that the organ of the body easily associated with it is the heart. Quite a number of explanations have been provided by various individuals to justify this. I've heard so many people say that because the heart sustains life, when someone says he loves you with his heart then it means he actually loves you with his life. Some folks see the heart as being the most important of all organs and for this reason, if there is a love that would make a man give out his heart (literally now) to another person, then that love can only be the highest form of it. While these are important and quite convincing attestations to why the heart and not the brain or any other organ is fit as the organ of love, they are not sufficient to feed skeptical or curious minds on the issue. After a long while of deliberating on the subject, something caught my attention; love is being 32 demonstrated among the body organs. An organ supplying a substance of life was actually found to be taking the least percentage of that substance! Do you get that? This organ is the supplier of this particular substance, this substance is needed by every organ including itself to survive but yet it takes the least volume of this substance. It pleases this particular organ that it has the least so that every other organ can have sufficient supply. Nobody would pick it up against you if you conclude by saying that this organ must care little about itself. This is because, despite the r i s k s i n vo l ve d , t h i s o r g a n overworks itself when any of the other organs in the body (e.g. the kidney) is failing. When the body is short of the substance of life, this organ stresses itself out to make sure each of other organs still has t h e r e q u i r e d q u a n t i t y. Interestingly, although this organ can almost survive on its own it will not do so in the face of ailing other organs. This can be regarded as a selfless service of love. Just imagine someone spending only about 5% of his salary on himself and the remaining 95% on his loved ones. This person can obviously live without them but wouldn't do so. Why? Only because he sees the life of others as being more important than he considers his to be. He derives his joy from what he can provide for others. So, it pays him more to have just 5% of his salary to himself and see his loved ones make do with the remaining than it being the other way round. Such is the case of the heart which supplies blood to all other parts of the body. But then, it uses the least volume of it! The heart supplies the brain with 14% of blood, the kidneys with 22%, liver with 13%, skeletal muscles with 18% and so on. The heart only makes do with 4-5% of the total blood available (the cardiac output). This is the very least, compared with the percentage of cardiac output it pumps to each and every other “Love is so wonderful that the organ of the body easily associated with it is the heart” org an. T he hear t does this continuously till the very end of life. It is an endless service; a kind of love that the heart is dedicated to among other organs of the body. The heart portrays love that delights in giving and never expects anything in return; the love that shares in joy and sorrow, pain and comfort, good and bad times, fears and strengths of the other person. The love that never expects much but will be there at all cost; it is a love that never ends, one that continues even till the very last moment. It is an endless service of care, passion, adoration and devotion to things concerning the other partner. The heart remains faithful even to the end. This is the kind of love that should be among individuals or group of individuals who claim to be in love. It is love whose example is led perfectly by the perfect organ of love which is and will always remain the HEART. If you must love any person, then make sure your love is selfless, faithful and above all endless. Oladehinde OluwasegunAbiola The Real Mentor; continued from pg. 30 · Mentors succeed: They not only are successful themselves, but also foster success in others. · Mentors are admirable: They are usually well respected in their organization and community. As a mentee, do the following; · Ask questions. · Listen carefully. · Be open to criticism from your mentor, accept it graciously and be willing to make amends. · Don't be afraid of trying new things or testing new ideas. · Carryout every assignment or project given to you by your mentor. · Above all, reference your mentor and show appreciation for your mentor's time and dedication to your success. How to find a good mentor · Consider first what exactly you want from a mentoring relationship. · Think about your personality style and what type of person will complement and benefit you best. · Think about the people who you looked up to in the past, perhaps a teacher or supervisor who · · · · · · · was especially helpful to you. Make yourself a good mentee. List out the things you want to learn. Do your research on your potential candidates. What are your goals? How do you think the mentor can help? How often and where do you envision meeting? Don't exploit his/her rolodex -build a relationship. Don't use a mentor just for his/her connections. You are creating a relationship that is about leveraging your mentor's experience and insights, not about exploiting their rolodex. You will get the connections they think will be helpful to you in the long run. “However, true mentoring is more than just answering occasional questions or providing ad-hoc help. It is about an ongoing relationship of learning, dialogue, and challenge”. BY OLAGUNJU MUYIWA J. 33 T U B E R C U L O S I S By Adetona Olugbenga According to the World Health Organization (WHO) Global Tuberculosis Control as at 2009, there were an estimated 9,4 million incident cases of tuberculosis (TB) globally. Provisional analysis of this data by age and gender indicates that women account for an estimated 3-million cases. In 2008, most of these estimated cases occurred in Asia (55%) and in Africa (30%). The five countries that ranked first to fifth in terms of total number of incident (new) cases of TB in 2008 were: • India (1.6–2.4 million) • China (1.0–1.6 million) • South Africa (0.38–0.57 million) • Nigeria (0.37–0.55 million) • Indonesia (0.34–0.52 million) TB is a curable disease only if patients are given a complete and uninterrupted course of drug therapy and if they take these medications as prescribed. Pharmacists have an important role to play in the management and prevention of TB especially in aspects related to improving availability and accessibility of drug treatment; improving adherence to therapy and educating patients on the treatment and on the disease. 34 PATHOPHYSIOLOGY The disease spreads from one person to another through cough and sneeze. It occurs when droplets of Mycobacterium tuberculosis are suspended in the air and then inhaled into the lungs. Once in the alveoli, macrophages attempt to ingest the bacilli, and if the bacilli continue to multiply, macrophages may rupture and release the bacilli, causing the spread of the bacteria to the lymph nodes and possibly into the blood. A few weeks after exposure, macrophages typically form granulomas to hold the bacilli and prevent the spread of the infection. Bacilli contained within the granulomas may become dormant, resulting in latent tuberculosis infection(LTBI). Patients with LTBI are not infectious and cannot spread the disease. In 10% of infected patients, LTBI may progress to active TB. Patients with active TB are infectious and can spread the disease. ANTITUBERCULOUS AGENTS Tables 1 and 2 highlight the first- and secondline antituberculous agents. Typical doses used in the treatment of active TB as well as selected adverse events and monitoring parameters associated with these medications are also listed. One of the main adverse events associated with antituberculous agents is druginduced hepatitis, which is defined by an elevation of the serum aspartate aminotransferase( AST) level three or more times the Upper Limit of Normal (ULN) in the presence of symptoms, or an elevation of the serum AST level more than five times the ULN in the absence of symptoms. In this case, all hepatotoxic agents should be discontinued immediately, and two or more nonhepatotoxic agents may be used. When the AST level drops below two times the ULN, first line agents may be sequentially reinitiated with close supervision. Pharmacists’ intervention Pharmacists play a vital role in the management of patients with TB by providing their expertise within an interdisciplinary team approach to patient care. They can assess the appropriateness, efficacy, and safety of antituberculous therapy by monitoring patients and ensuring medication adherence. They can educate patients and clinicians about the expected therapy outcomes and the side effects as well as drug interactions associated with antituberculous agents. Minor adverse events such as gastrointestinal disturbances are common in the first few weeks of therapy and usually do not necessitate discontinuation of first-line agents. Patients may choose to take their medications with food, although absorption may be delayed. Other adverse events such as druginduced hepatitis, pyrazinamide-induced hyperuricemia, and ethambutol-induced optical neuritis are more serious, require further evaluation, and may necessitate discontinuation of therapy. Pharmacists may recommend pyridoxine to decrease the risk of isoniazide-induced neuropathy. They should screen patients with co-morbid conditions such as HIV infection for potential drug interactions particularly those patients receiving rifamycins and protease inhibitors. Pharmacists can also educate patients and clinicians about the importance of adherence and Directly Observed Therapy (DOT) to ensure efficacy and minimize resistance. They should remain vigilant to avoid the addition of a single agent to a failing regimen. Studies have shown better outcomes and substantially 35 improved rates of treatment completion when pharmacists are directly involved in the management of patients with TB, including healthcare workers. Institutions should explore the possibility of adding a pharmacist to their TB management team. CONCLUSION The mainstay of TB control is organising and administering standardised treatment across the country for all adult and paediatric TB cases. Pharmacists already contribute to thesafe and effective use of medicines throughout the healthcare system. They also have a critical responsibility towards ensuring a consistent supply of medicines, promoting rational use of drugs and providing information to patients and this should be no different for anti-TB medicines. The private and public sector need to work together if TB is to be brought under control. Government needs to begin to involve the private sector in tuberculosis control programmes, so as to ensure a more comprehensive management of TB patients. SUCCESS ATTITUDE IS AN A positive attitude is by far the most important asset on the search for greatness. Here greatness means; “achieving personal, social and professional goals” Everyone finds himself in a certain environment, under a given physical condition, or state of well being, with certain obstacles and limitations. We find ourselves individually and in our own respective worlds. Things within our world become our environment which tries to influence our actions and reactions, by affecting our thoughts, through the pictures and imaginations they create in our minds. Success is not a game of chance but a product of hard work and it is the ability to get along with some people and ahead of others. The origin of our success or failure is our minds. This is because when we think and plan well about something, we generate good and positive thoughts which lead to positive feelings that produce positive actions and reactions that lead to success. But when one fails to plan about something, then he is planning to fail. Success 36 “…we should try to master everything in our individual lives because the principle of our being contains the possibility of complete mastership” depends on our ability to think, plan and programme ourselves towards what we want to do. Hence, as students or people, our success or failure is a function of our attitude. However, what we are and what we do determine in what condition, circumstances and environment we shall be placed, we must change ourselves and actions by changing our thoughts. The major cause of failure ranges from personal attitude to negative environmental influence. Here, personal attitude includes inefficient planning, procrastination, lack of focus, inefficient time and financial management, negative influence from friends, family members, social groups, campus environment and the society at large. However, for us to overcome these so as to become champions of our time, the following positive personal attitudes should be exhibited; we should efficiently plan everything we want to do, ensure proper time and resource management. We must avoid every distraction that leads to procrastination and loss of focus. Besides, we should try to master everything in our individual lives because the principle of our being contains the possibility of complete mastership. Since the realization of this principle produces the attitude of self-supremacy, every original thought that our minds create will, 37 to a degree, change us and remake us according to what we inwardly desire to be. Finally, success is all about creating or recreating ourselves in addition to God's grace that is already available. This explains that, to be successful our negative attitudes should be restructured to positive ones even as we go about creating new positive attitudes. It is only the creative power of thought that is employed in the construction and reconstruction of a man; for this reason, we are who we think we are. Hence, students should remember that, proper preparation prevents poor performance. Therefore, our success is an attribute of our attitude. By ADOMOKEME EBI FELIX, NDU ? e m a l B o t s i o h W She couldn't just believe what the doctor had told her. The result of the test shouldn't have been hers. She was 2 months pregnant. How could it be? With the careful measures she took with her husband to avoid this scenario. She was completely lost. She thanked the doctor, got up and went home preparing to disclose the news to her husband who couldn't have seen that coming. The words of her father kept playing in her head as she drove down the road; "Save the world and save yourself the stress, do not get pregnant", her dad always emphasized. Ta mu n o wa s d i a g n o s e d o f t h e H u m a n Immunodeficiency Virus about 3 years ago. It was news hard for her to take as she had always been careful with use and sharing of sharp objects, towels and even sex, but with support from her parents she was able to stay strong. Her parents encouraged her to join HIV organizations, where she could meet with people, share ideas, and be taught on how to manage the disease amongst other reasons. She attended such meetings with keen interest. It was in one of these meetings Tamuno met George who was also HIV positive. They had a lot in common, the rationale behind their coming together so quickly, except for their family background. George was from a humble home while Tamuno's parents were quite rich; they could afford the basic necessities of life with a little more luxury in contrast to George who lost his parents to an automobile accident. He was the first child and was left with four siblings to take care of. When Tamuno told her parents she was getting married to George, they gave her all the support she needed. They were both HIV positive, a reason why her parents weren't bothered about George's financial status. All they wanted was to have their daughter happy. A day to their wedding, her father called Tamuno and George. He promised to help them financially and employ George in one of his companies. These promises were not without a stiff condition; they must not have a child. “What is the use of having an HIV positive child who would give more stress than joy”? Tamuno's father 38 survived the incident but not without losing more than enough blood which she needed in the course of her treatment. Tests had to be run before blood could be transfused. The result of the test was a shock. Tamuno was going to hear what was going to change a lot in her life. She was HIV negative! On hearing this, in the midst of undifferentiated emotions, George also requested to have his blood tested again; the result, which to everybody's surprise including the consultant, showed he was HIV negative. What could have happened? Could it have been a mix up? Were their previous test results swapped? This was more than a coincidence. Could they say it was a miracle? Her father heard the news of what had just happened and he was ashamed. He wanted to make it up to them. Tamuno didn't want to see her father. The thought that her baby could have been free from the disease and would have been saved if her father had rendered help made her sad. She was hurt and nothing anyone told her could pacify her. Who is to blame? Is it her father, Tamuno and George, the laboratory scientists who had carried out similar tests on them before, or were they just victims of circumstance? would always ask. He didn't believe that there was any medical process that would prevent the fetus from contacting HIV from the pregnant mother. He threatened to disown Tamuno if she ever had a child, so getting pregnant was not an option. Tamuno told her husband about the pregnancy. She wasn't ready to abort the pregnancy. George was not going to suggest that either. They both decided to keep the child, damning the consequence. Not long after, her father got to know. He was very angry. He promised to carry out his threat if she would not go for an abortion. She already had a bond with her unborn baby, and Tamuno's father made good his threat. He withdrew all forms of support towards them in addition to sacking George from his company. Life became hard for the young couple. They lived on mercies of friends and a few family members. Tamuno couldn't afford a proper ante-natal during pregnancy. There were a lot of drugs she wasn't able to buy. She also wasn't feeding properly. By: Adediran Olatoyosi E. A week after the eighth month of her pregnancy, Tamuno felt a sharp pain in her waist. She let out a loud cry, loud enough that it attracted the attention of their neighbors, and George who was lucky to be at home. She was taken to the hospital where the doctor told George how Tamuno had suffered complications due to her deprivation of a proper ante-natal. She would have to undergo a caesarian section if they wanted both Tamuno and her baby alive. They needed money and time was of essence. After he had tried sourcing for money from some friends with little success, George decided to go to his father-in-law. Tamuno's father would have none of it and all he could do in the face of anger was to drive George out of this compound. Tamuno eventually lost the baby. She was lucky to have 39 Introduction Liposomes are composite structures made of phospholipids and may contain small amounts of other molecules. Though liposome can vary in size from low micrometer range to tens of micrometers, unilamellar liposome, are typically in the lower size range with various targeting ligands attached to their surface allowing for their surface-attachment and accumulation in pathological areas for treatment of disease. Liposome is one such type of structure that has been the subject of significant research and development for many years. The use and potential of liposome (Figure 1) as drug deliverers continues to grow in importance. The reasons are clear: · Drugs delivered via liposome may be protected from the actions of metabolizing enzymes · Lipophillic drugs may be made soluble · Drugs can be targeted to specific areas by attaching ligands to the liposome · Liposomes are readily absorbed by cells · The rate of drug release may be controlled by the selection of liposome · Using liposome as a drug deliverer allows potentially lower doses of drug to be used, red uci n g toxi ci ty a n d si d e-ef f ects. Furthermore, it is possible that gene therapy drugs may be delivered by liposome. The size of the liposome is increasingly being recognised as an important factor in treatment efficacy. The size of the liposome used in drug delivery may affect its circulation and residence time in the blood, the efficacy of the targeting, the rate of cell absorption (or endocytosis) and, ultimately, the successful release of its payload. Such size considerations are also hugely important to nanoscale polymer-encapsulated drug delivery systems. Accurate measurement of the particles being administered is therefore important. This mode of drug delivery lends more safety and efficacy to administration of several classes of drugs like antiviral, antifungal, antimicrobial, vaccines, antitubercular drugs and gene therapeutics. Present applications of the liposome are in the immunology, dermatology, vaccine adjuvant, eye disorders, brain targeting, infective disease and in tumour therapy. The new developments in this field are the specific binding properties of a drug-carrying liposome to a target cell such as a tumour cell and specific molecules in the body (antibodies, proteins, peptides etc.); stealth liposome which are especially being used as carriers for hydrophilic (water soluble) anticancer drugs like doxorubicin, mitoxantrone . The polar character of the liposomal core enables polar drug molecules to be encapsulated. Amphiphilic and lipophilic molecules are solubilised within the phospholipids bilayer according to their affinity towards the phospholipids. 40 MECHANISM OF ACTION OF LIPOSOME ENCAPSULATED DRUGS The general approach is to deposit drug bearing liposome directly into the site where therapy is desired. Since liposomes are large and do not easily cross epithelial or connective barriers, they are likely to remain at the site of local administration. The liposomes would then slowly be released into the target site or perhaps create a local drug level higher than the systemic level. Alternatively the drug loaded liposomes might interact directly with cells in the target site, without producing release. The goal of this approach is to maximise the amount of effective drug at the target site, while minimizing the drug levels at other sites and thus decreasing systemic toxicity. For e.g. Small Unilamella Vesicles (SMV) injected into the skin can persist interact at the site for 600 hrs. And release of entrapped markers from the liposome occurs only after cellular uptake and intracellular space remain intact. The liposomal drug tends to have the following Pharmacodynamic effects 1. Retardation of drug clearance from the circulation 2. High drug accumulation in tissues rich on RES especially in liver and spleen 3. Retention of drug in tissues for large period 4. Protection of drug against metabolic degradation. APPLICATIONS OF LIPOSOMAL DRUG DELIVERY SYSTEMS 1. Cancer chemotherapy as anti tumour drugs e.g. Methotrexate, Cytarabin 2. Gene therapy to deliver DNA into the cells 3. Immunological adjuvant for protein antigens(diphtheria toxoid) Doxorubicin, Daunorubicin, 4. Carriers of drugs in oral treatment of arthritis e.g. ibuprofen, cortisol palmitate and diabetes e.g. insulin 5. Ophthalmic delivery of drugs e.g. Idoxuridine ,Triamcinolone acetonide , Benzyl penicillin indoxol, Inulin , Penicillin G 6. Pulmonary delivery of drugs e.g. cytocine arabinoside, penthamidine and sodium chromoglycate. REFERENCES 1. Soman, R., Vimal M., and PraveenHH, M. (2009). “LIPOSOMES – A Novel Drug delivery system”. 2. Samad, A., Sultana, Y and, Aqil, M. (2007).”Liposomal Drug Delivery: An Update review”. 4, (4), 297305 available at http://www.ncbi.nlm.nih.gov/pubmed/17979650 Accessed: 6/05/2013. http://en.wikipedia.org/wiki/Liposome 3. Accessed: 6/05/2013. 4. Priyanka, R., Jaydeep D, Y., Kumar A, A., (2011).” Liposome: A Novel Drug Delivery System”. International Journal of Current Pharmaceutical Research. 3, (2), 1-3. 41 BY ADELEKE OLABIMPE INTERVIEWWITH PROFESSOREBENEZER OLARENWAJUOGUNLANA EXCLUSIVELY WITH PHARM. PROF. SIR E.O. OGUNLANA (OON, FPSN), a rare breed, a dis nguished icon in Pharmacy profession in Nigeria and an erudite scholar, a teacher of teachers, a dean of deans and a professor of professors. CAN WE MEET YOU SIR? My name is Ebenezer Olarenwaju Ogunlana. I hold Pharmacy in good faith and will always endeavor to do the best for the profession. CAN YOU TELL US ABOUT YOUR BACKGROUND SIR? I was born in Lafiaji, Lagos. My father was a printer and my mother was a school teacher. Unfortunately, my father died when I was a year and two months old, so, my mother had to bring me and my elder brothers up. I therefore hold my mother in high esteem because without her, I wouldn't be who and where I am now. I went to Tinubu Methodist School and then Methodist Boys High School. Fortunately, I was swift to learning and at that time left school at the age of 17, after which I worked for about 2years. At a time, I fell ill and was admitted into a general hospital which happened to be where and at the time Kuti was pursuing his internship. My liver was badly attacked by malaria, so, I was told to rest my liver; thank God I survived. I then travelled abroad. I did my A'levels in Birmingham and then went to Nottingham University. I even did A'levels twice since I was not satisfied with the result I had the first time. Fortunately for me, I was the first Nigerian to be admitted into Pharmacy in Nottingham University. WHAT WAS THE DRIVE THAT BROUGHT YOU INTO PHARMACY? DID YOU ALWAYS WANT TO STUDY PHARMACY? Well, I wanted to do Classics which was what I always had in mind until the time I fell ill. During my stay in the hospital, a man was brought into the ward and then diagnosed with cerebral malaria. One night, he suddenly got out of his bed and started throwing people out of their beds, fortunately, he did not touch me. Odeku who was also a houseman at that time was brought in from night duty and tried giving the man some drugs to stop him. Every time Odeku tried getting drugs that would calm the man down from the pharmacy, the drugs were always not available till the man became a pest. But, eventually he got a drug that calmed the man down. This-the unavailability of the needed drugs-really got me wondering what went wrong that a diligent doctor who was trying all he could to help a patient out could not, due to the absence of the required drug. This experience made me change my interest from Classics to Pharmacy. C A N YO U T E L L U S S O M E O F YO U R ACHIEVEMENTS SO FAR SIR? Well, where do I start? OK, I got PhD from Purdue, then I came home (Nigeria). I worked as a lecturer at University of Ife (from 1963). I became a professor in January 1976 and then became the first Nigerian to be made the Dean of the Faculty of Pharmacy in Ife (invariably in Nigeria) in March 1976 which happened to be the month I clocked 40. I was then made a fellow of the Pharmaceutical Society of Nigeria (FPSN) in 1977. I became the Deputy Vice-Chancellor of University of Ife on 1st of August, 1980. In 1977, I composed the 'Oath of Pharmacists in Nigeria' which is usually recited by fresh graduates at their induction ceremonies as pharmacists. In 1981, I was elected president of the West African Health Community (WAHC) apart from being made a chief in Ife. I received the title “Maye of Ketu land”. In December 1989, I was appointed a Federal Drug Analyst. As a surprise to me, in March 1990, I won the 'AndreBedat Award 1990” by Federation Internationale Pharmaceutique (FIP) with this inscription, “to an outstanding practitioner who has made significant contributions to Pharmacy at the international level”. In 42 1993, I became the president of the Pharmaceutical Society of Nigeria (PSN). There are lots of achievements but to mention a few. I must say that the students I taught are now professors, MD CEOs and successful individuals in different walks of life. SIR, WHAT DO YOU HAVE TO SAY ABOUT PHARMACY PROFESSION; HOW IT WAS YEARS BACK AND ITS FUTURE IN NIGERIA? My generation came in when the profession was not well recognized. We had to walk up to recognition. When recognition came, we saw it and it developed. But personally am seeing a situation where complacency is setting in. For instance, pharmacists two generations after us don't have respect for elders. It should be noted that, any profession that does not respect its elders is bound to fail. We must talk more to each other as professionals. It seems to me like we don't know where we are going, but, it is left to you as the younger generations to determine. There is need for us to reflect fully by asking ourselves individually the following questions: where did I come from? On what basis did I come? Where am I to take the issue for the future? All these questions are very important to determine the future. instance; research, development skill, interaction or other areas. WHAT WAS THE INSPIRATION BEHIND THE PHARMACIST OATH OF 1977? Having decided I was going to do Pharmacy and then teach, I started asking myself what I was going to do in that teaching. In 1976, when I became the dean of faculty of Pharmacy in Ife, I took the oath which Hippocrates wrote and perused it. I then gathered information from different other sources and then came up with an oath eventually having in mind the question of what we were going to do as professionals to be responsible. I then tested the oath at my base in Ife and then went to the pharmacy board with Mr. Coker as registrar at that time. As a pharmacist, you should not self advertise. Focus on your patients, your colleagues, and then the future. WHAT IS YOUR FINAL MESSAGE TO PANSites sir? Not everybody can change the world; only a few people can. Gather up like minds and discuss what has become of our profession, then what will become of it in years to come. When you have done this, share your observations with a larger group. You should be consistent, prepare to recognize your faults and wrong moves and then make amends. WHAT IS YOUR TAKE ON PHARM. D. IN NIGERIA? I refuse to get involved in the controversy going on concerning Pharm. D. The programme should aim at making the practitioner more useful to the environment. What I feel about Pharm. D. is that we have not discussed it enough because we need to decide what areas emphasis should be laid. We need to define the areas where Pharm. D. should polish. For 43 Benefits of Drinking Water Drinking a healthy amount of water is vital to your health. You gain tremendous health benefits and it sometimes replaces migraine medicines and pain killers. The functions of water in the human body are vital. Water 1. Transports nutrients and oxygen into cells. 2. Moisturizes air in the lungs. 3. Protects our vital organs. 4. Detoxifies. 5. Helps our organs to absorb nutrients better. Every cell in your body needs water from head to toe. That is why it is so important to drink enough fluid. If enough water is not supplied to the body, the brain will not function well leading to headache and migraine which are signs of dehydration. HEALTH BENEFITS OF DRINKING WATER. 1. To lose weight: Drinking enough water helps you lose weight because it flushes down the byeproducts of fat breakdown. Drinking water reduces hunger; as it's an effective appetite suppressant so you'll eat less. 2. Natural remedy for headache: Water helps to reduce headache and back pains due to dehydration. There are many reasons for headache but a very common reason is dehydration. 3. Look younger with healthier skin: You'll look younger when your skin is properly hydrated. Water helps to replenish skin tissues, moisturizes skin and increases skin elasticity. 4. Better productivity at work: Your brain is mostly made up of water, thus drinking water helps you think better and also become more alert and concentrated. 5. Better exercise: Water also helps to fuel your muscles; that means you'll feel more energetic 44 6. 7. 8. 9. 10. By Adeyemi Kehinde when doing exercises. Helps in digestion and constipation: Drinking water raises your metabolism because it helps in digestion. Fiber and water go hand in hand so that you can have your daily bowel movement. Less cramps and sprains: Proper hydration helps keep your joints and muscles lubricated, so you are less likely to have cramps and sprains. Helps to boost the immune system: Drinking plenty of water helps fight against flu and other ailments like kidney stones and heart attack. Helps the body get rid of wastes and toxins: Water is used by the body to help flush out toxins and waste products from the body. Reduces the risk of cancer: Related to the digestive system, studies have shown that drinking a healthy amount of water may reduce the risks of bladder cancer and colon cancer. CONSEQUENCES OF NOT DRINKING A HEALTHY AMOUNT OF WATER. 1. Tiredness 2. Migraine 3. Constipation 4. Muscle cramps 5. Irregular blood pressure 6. Dry skin 7. Kidney problems C O M M O N S Y M P T O M S O F DEHYDRATION. 1. Coloured urine. 2. Dry skin. 3. Thirst. 4. Hunger. 5. Fatigue. INTERNATIONAL PHARMACEUTICAL STUDENTS' FEDERATION By Anzaku A.A IPSF stands for International Pharmaceutical Students' Federation. It was founded in London in 1949, the International Pharmaceutical Students Federation (IPSF) is one of the World's oldest international student volunteer organization. IPSF is the leading International advocacy organization for Pharmacy students with the aim to promote improved public health through provision of information, education, networking as well as a range of publications and professional initiatives. Today, the Federation represents over 350,000 Pharmacy students and young graduates from 84 countries world wide. The headquarters is Hague, Netherlands and the official languages are English, French and Spanish. · Establishing a permanent form of contact with representatives. · Promoting the exchange of ideas by international correspondence and by encouraging full dissemination of scientific and professional knowledge. · Encouraging the formation and development of national pharmaceutical students' organizations without trespassing upon domains. · Covering opinions and information on the subject of pharmaceutical education and by suggesting improvements where necessary with the aim of attaining unification of pharmaceutical education. · Encouraging member associations to organize annual inter national phar maceutical students' congresses; · Encouraging and promoting international visits and exchange of students. · Publicizing the IPSF News and Bulletin as an official organ amongst many others. The ideal of forming this impeccable establishment in 1948, though it is a non governmental organization, was brought from the then secretary of the Britain Pharmaceutical Students' Association, Stephen B. Chauen during the 6th annual congress of BPSA. The constitution of the Federation was agreed and signed on August 25, 1949 in London during the inaugural conference, marking the organization's founding date. On the same day, Sydney J. Ralph was elected as the first president of ISPF along with 4 other Executive committee members. The Eight (8) founding countries were Australia, Austria, Denmark, Iceland, Ireland, Netherlands, Switzerland and the United Kingdom. Regional offices The IPSF office is a functional extension of the IPSF Executive structured by elected students from IPSF member countries of specific IPSF region, forming Regional working group. Its mission shall be to advance and support the aims and objectives of the Federation at regional level. African Regional Office (AFRO) was established in 2008. The website is www.ipsf.org. The chairperson of the African Regional Office 2012/2013 is Mr. Diallo Afadhalli from Rwanda. It is suffice to say that several IPSF congresses has been holding from 1949 till last year. The next congress that will be holding in August will mark the 58th World IPSF congress. All hands are on deck in making sure that our great country is featured in the congress this year. IPSF is the leading international advocacy organization for Pharmacy students and recent Pharmacy graduates, promoting improved public health through provision of information, education, networking and a range of publications and professional initiatives. Objectives of International Pharmacy Student's Federation 45 THE If over the years there has been anything which has succeeded in uniting the world, it has to be sports. Ranging from the popular ones; football, basketball, sprinting, volleyball, tennis, and golf, to the likes of boxing, hockey, cycling, swimming, car racing, skating that we are less familiar with, and extending to the least popular ones, those of unicycle polo, fencing, cricket, chess boxing, snowboarding, and the rest, the broadness of sports' spectrum seems to be without boundary. Sporting events running all year round, most especially the more glamorous ones-the likes of UEFA champions league (football), FIFA world cup (football), Tour de France (cycling), Wimbledon (Tennis), Olympic games, Ryder cup (golf), Rugby world cup (Rugby), Formula one (Racing), Melbourne cup (Horse racing), and Cricket, are not only a glamorous platform for bringing together millions of people from various parts of the globe but have always succeeded in getting hundreds of millions of fans glued to their television and/ or radio sets. The spirit of the game is a heated one, and the hope and joy of victory is something that resides in the heart of ever y athlete. They therefore do all they can-they are always ready to go the extra lengthto achieve not just victory but a record smashing glory. In the course of preparation, efforts often put into competitions by athletes include; vig orous but steady physical and mental trainings, SECRETS TO A SUCCESSFUL SPORTING CARRIER By: OLADEHINDE OLUWASEGUN ABIOLA ([email protected]) 46 dieting to keep fit, muscle building, and the use of medications, to mention the usual. Various rationales usually tendered to justifying the use of drugs by athletes vary, though with no sharp boundary. While most athletes take drugs to enhance their physical performances in the bid to prevent them from falling behind other competitors (not minding the effect of the drugs on their health), other athletes take drugs to help them relax, summon up confidence, build up self-esteem and to be able to cope with the stress associated with the constant will to win at all times. To reduce the pain of injury that arises during training and even perfor mances, medication administration cannot be denied. Medications and food supplements that can be considered as being fairly 'legal' and safe to use and at the same time provide a performance benefit in s p o r t s, i n a d d i t i o n t o h av i n g medical/therapeutic benefits, are the bicarbonates, beta-hydroxyl, calcium carbohydrate powders, glucosamine and chondroitin, intramuscular vitamin B12, melatonin, recovery formulas, skim milk powder, sport drinks, specific vitamins and minerals. However, the use of many drugs that are deemed to providing unfair advantages, pose health risks or seen to violate the 'spirit of sport' by athletes is referred to as 'doping'. These drugs are considered illegal and are as such banned. The International Olympic Committee (IOC) and the World Anti-Doping Agency have been leading the way in the battle against drugs in sport. Among these are the major medications indulged in by athletes, including the likes of; § Lean mass builders: to increase the g rowth of muscle and lean body mass and to reduce recovery time after injury, athletes use lean mass builders such as anabolic steroids, beta-2 antag onists and human growth hormone (hGH). Lean mass builders are sometimes used to reduce body fat. Stimulants: the game of sports is an endeavor that calls for adequate alertness, and full concentration. To facilitate these, in conjunction with increasing aggressiveness and decreasing fatigue, athletes often indulge in the use of stimulants. § Pain killers: injuries are always almost inevitable and to maintain a continual efficient perfor mance, athletes cannot do without analgesics. § Relaxants: alcohol, betablockers and marijuana are the commons in the league of r e l a x a n t s e m p l oy e d b y athletes. They are seen as of core importance in such sports as archery and javelin where a steady hand is required, and also by those individuals who do feel excessive nervousness or discomfort during competitions. § Diuretics: in sports such as wrestling where cer tain weights need to be met, diuretics are often used for the removal of water from the body. One other method of performance enhancement employed by athletes is what is commonly referred to as 'Blood Doping'. T his involves removing red blood cells from the blood and replacing them weeks later to increase the overall number of red blood cells in the blood. This in essence increases the amount of oxygen the blood can transport. Blood doping is of significance in long distance races. Quite a number of these drugs are considered illegal and hence banned not only because they give an athlete 'unfair' advantage over another but also due to the side effects and risks associated with their use. For lean mass builders such as anabolic steroids, they can cause 47 § severe increase in cholesterol levels, stroke, liver disease, hypertension and heart attack, aggression, depression and mood swings, acne and skin diseases, low sper m count and impotence in males, and of course, amenor rhea in females. Beta-2 antagonists cause nausea, headache, dizziness, muscle cramps, and heart flutters. The use of other lean mass builders such as human growth hormone can result in irregularities in the processing of insulin and may as well be associated with liver problems and heart diseases. Side effects of stimulants (e.g. amphetamines) such as tachycardia, hypertension, and increase in body temperature, stroke, agitation, and sudden cardiac death are often the result of prolonged excessive use of these drugs. Strong prescription products such as narcotics are highly addictive and are reputed to causing impairment of mental abilities. Alcohol, marijuana and some other relaxants impair judgment, balance, c o - o r d i n a t i o n , a n d m e m o r y. Hallucinations and drowsiness are also often re por ted following excessive use. While the side effects of diuretics are usually dehydration, cramps, heart damage, and kidney failure.The method of blood doping is not a perfect option either. Thus, its employment is discouraged. It causes blood thickening, and at the same time, can lead to hypertension, stroke, heart attack, and even sudden death! In order to disguise the use and detection of illegal drugs, athletes use masking drugs. These drugs however are not without their own risks as they have the tendency to cause severe allergic reactions, nausea and vomiting. As much as athletes crave for the joy of victory and are always ready to travel past the 'normal' length to achieving it, they should bear it in mind for themselves that the secret to a successful and livelong sporting career lies in a fit and sound health. If all you always want is to win no matter what, then don't let your health fail; it's of most worth. 48 Live longer with your eyeS C L O S E D In quest for success, we toil for years in school with a view to attaining the means by which we could live comfortably with life's necessities and so-called 'luxuries of life'. However, we neglect paying cognisance to something that is just as important-which should be classified in the same league-as prayer, determination, and hard work, which are distinctive benchmarks of every successful student. We pay little or no attention to our dear “friend”- SLEEP. Sleep, a state of reduced consciousness during which all voluntary activities are suspended, is essential for a person's health and well being. Yet many people do not realize how significant it is. Instead, they may think of it as a waste of time. The result of this is that millions of people do not get enough sleep and many suffer from lack of sleep-a condition known as 'insomnia'. A recent survey found that more people sleep for less than six hours a night, and sleep difficulties visit 75% of us at least a few hours per week. Now the question is: How important is sleep? While asleep, we go through phases of sleep, called 'rapid eye movement', every 60 to 90 minutes throughout the night. During these phases, the brain is most active, and researchers believe it is performing some kind of selfrepair. When sleep cycle is interrupted and sleep is lost, it has a cumulative effect on the body. Brain function is affected, which results in mental inefficiency, among a host of other physical ailments. Sacrificing needed sleep can weaken our immune system, for it is during sleep that the body produces T-cells that fight against pathogens. During sleep, our body also produces the hormone Leptin, which helps to regulate appetite. The implication of this is that absence or lack of sleep impairs appetite regulation. Chronic sleep loss can contribute to health problems such as weight gain, high blood pressure, and a decrease in the body's immunity. Indeed, the body needs sleep as much as it needs proper exercise and nutrition. Taking sleep for granted, eating and drinking late, stress, drug side effects, pregnancy, other medical conditions, too much caffeine, alcohol and the use of sleeping tablets are some of the common reasons why people do not get enough sleep. Sleeping tablets?! Yes, though they are okay to use occasionally, they stop working well and you may become addicted when they are used regularly as your body system gets adapted to them. Substances such as caffeine can for the short term block the chemical compound that signals the need for sleep. In prevalence of sleep depriving conditions, the brain has its own mechanism of causing sleep to occur when the body has not had enough resulting in 'microsleeps'episodes of sleep which may last for a fraction of a second or up to thirty seconds. No matter what you 49 happen to be doing; your sleep-deprived brain will periodically go into the first stage of sleep for a tensecond microsleep. During that time, you would have travelled more than the length of a football field. It's a deep sleep indeed. Is extra work robbing you of much-needed sleep? Do not allow anxieties of life and worries about the future weigh you down from getting the required amount of sleep. The wise king Solomon once observed: “Sweet is the sleep of the one serving, regardless of whether it is little or much that he eats, but the plenty belonging to the rich one is not permitting him sleep.” · · · Regular exercise for a total of about 90 minutes each week helps us sleep soundly and contributes to the total well-being of the body. The following reasons affirm why we need to treasure sleep: · LEARNING AND MEMORY: Sleep helps the brain commit new information to memory through a process called memory consolidation. Studies have shown that people who had adequate sleep after studying did better in tests than those who didn't. · METABOLISM AND WEIGHT: Chronic sleep deprivation may cause weight gain by · 50 affecting the way our bodies process and store carbohydrates, and by altering levels of hormones that affect our appetite. SAFETY: Sleep debt contributes to a greater tendency to fall asleep during the day. These lapses may cause falls and mistakes such as errors, domestic accidents, mishaps, and road accidents. MOOD: Sleep loss may result in irritability to concentrate, and moodiness. It can also leave us too tired to do the things we have to do. CARDIOVASCULAR HEALTH: Serious sleep disorders have been linked to hypertension, increased stress hormone levels, and irregular heartbeat. DISEASE: Sleep deprivation alters immune function, including the activity of the body's killer cells. Keeping up with sleep may also help fight cancer. Sleep is too relevant to be taken for granted, we need a good night's sleep to stay healthy, alert and fully energized all day long. So pray hard, work hard, play hard and live longer and better with your eyes closed. By ETOPIDIOK, ESTHER .J. IO D A R VE ACTI S NT E D U ST Radioactive Students The pharmacy profession is one that can be likened to the worth and value of a national treasure. It is held by the health sector of any community with high regard. The English diarist, Samuel Pepys (1633-1703), wrote in his diary“Thence I walked to the Tower; but Lord! how empty the streets are and how melancholy, so many poor sick people in the streets full of sores...in Westminster, there is never a physician and but one apothecary left, all being dead.” It is really quite difficult to imagine the th th 17 to 19 century without the apothecaries. Developments and tremendous discoveries have been made over the years. There's no telling the extent of health exploration the profession had brought to humanity. How I love the words of Henry Thomas Buckle (1821 - 1862) - “Among the arts, pharmacy, on account of its eminent utility, must always hold the highest place.” Phar macy is a profession so indispensable, a practice so delicate, an ambition so lucrative, and a course of study so interesting. The science, the practice, the diversity, the study, the opportunities, the breakthroughs, developments and the entire scope can undisputedly be traced to the fundamental pharmacy class room and her students. As beautiful and intellect demanding this field of science is, does its study really deserve all the energy, several hours in a day, about 5 labs a week, and sleepless reportwriting nights? This is a master question. A friend asked, “We go die say we wan be pharmacists? This course is draining life outta me. My mom barely recognized me the other day” This however, was during the r e g i s t r a t i o n e xe r c i s e a t t h e beginning of the 09/10 session here in the school of pharmacy. Being a part one student in the College of Medicine, University of Lagos as a student of pharmacy, was such a remarkable experience. Even with the availability of resources for good living standard at the period, you still may just look nothing different from hospital patients carrying back packs and lab manuals. If pharmacy were to be a bacteria species, it will best be considered a fastidious one. Spending cash in aliquot proportions may really be of no help. “I could hardly believe the velocity at which I had been losing weight these few weeks” a friend said. In response, Pharm. Olamide Bajulaiye said- “You are even still losing weight when most of us have lost ours a long time ago.” 51 st At the beginning of the 1 semester in the first quarter of the year, careful observation proved that these sassy and 'toosh' students had allowed the excitement of “School of pharmacy at last” elude the challenge that awaited them. “He's got the best clothes.” “He's cuter jare.” “She is hot!” These were whispers that emanated from cliques of gossips. At this phase of oblivion, the usual occurrence always takes place. What I refer to be the spontaneous disintegration of radioactive nuclei. A phenomenon highly influenced by the bombardment of unstable nuclei (pharm novices) with highly moving neutron particles…yeah, fast moving, with the velocity of light, according to Albert Einstein. We were bombarded at soul-point by these neutrons- series and episodes of lectures, hectic dub-ful lab reports, assignments, incourses, t e r r i b l e p hy s i o l o g y l e c t u r e situations and so on, in the reaction- i.e the semester. In fact it was a nuclear fission activity, and being a chain reaction, more neutrons were generated as the bombardment proceeded. Only God was our 'Baron rod', who helped check the regeneration of t h e s e n e u t r o n s f r o m e ve r y bombardment. TAKE RESPONSIBILITY FOR YOUR LIFE The world is a beautiful place to live in. The trees, the birds, the sun, the moon, the sea, the stars, the breeze all make it interesting. Imagine you go out there in the cool of the evening and you feel the effect of this rushing but cooling breeze that makes you want to forget yourself in the midst of your troubles and challenges and almost sweeps you off your feet. You then ask yourself what this life is really about. Life is full of experiences; it makes us who we are because it has a way of teaching us. It gives us the opportunity to fulfill purpose and showcase our talents in a unique way. Obviously, there are two sides to life: the good side and the bad side. Life is a journey - a never smooth one. It is full of ups and downs. While some are on the mountain, others are in the valley crying for help! Some people can afford to own a jet, send their children to universities abroad and can afford anything because resources are at their reach, while some others are struggling to even eat a square meal a day. They have no place to lay their heads and are feeding from hand to mouth; they are as poor as church mice. Why is life fair to some and unfair to others? Is this life not full of mysteries? Opportunity however, affects how far people go in life. This life is full of opportunities, but it depends on how well you grasp these opportunities and makes use of them. A child sent to school, for instance, might end up failing if he misuses the opportunity given to him, even if his parents are rich. Opportunities come and go; we only have to make something out of them. It is important to note that people you meet on your way up, can also be met on your way down and that is why it is always good to help people around you. It is a common saying that, what goes around comes around. The road in life is full of undulations. It is not always a bed of roses. One important thing that helps one in this journey of life is attitude. Attitude makes way for a man. Intelligence can take you to the top, but attitude is needed for sustenance there at the top. You must have the right kind of attitude because it attracts, just like beautiful flowers attract insects. Some come and go without leaving footprints in time or legacy for others to follow; some come and do what they have to do and leave fast, in fact, some have been living for decades, yet no one has heard of them in this same life! Life poses challenges, but you have to face them squarely and fight with every strength you have in you – yes, you must fight for what you want. If you don't stand for something, you will definitely fall for everything. This is why you need that driving force to keep you moving which is your will power. Nowhere in life is so smooth and predictable. No wonder Henry Beecher wrote “I know of only one easy place therein and that's the grave”. So you see that life is not that easy. In fact, it is not meant to be. It is not mathematics, hence, it is unpredictable. It is full of so many dreams but tell me, how well do you actualize these dreams? Life is dependent on time. There is no time to waste because every second counts. One thousand and one things happen to people every second…uhmn, the grave is full of dreams and is so rich in talents, purpose, gifts and so on but many have left this world without fulfilling their dreams. It is so sad! 52 10 A B C Health Benefits of A=Avocados Avocados, or also called alligator pears, are fruits that belong to the Lauraceae, a flowering plant family which also includes camphor, cinnamon. These fruits are believed to be originated in Mexico, where the name of “avocado” is derived from Aztech orNahuatl word 'ahuacatl', meaning 'testicle', a reference to the shape of the fruit. The avocados are very popular in vegetarian cuisine, as a substitute for meats in sandwiches and salads because of their high fat content. They are also popular in chicken dishes and as a spread on toast, served with salt and pepper. Avocados are considered as one of the healthiest foods in the planet because they contain in excess of 25 essential nutrients, including vitamin A, B, C, E, & K, copper, iron, phosporus, magnesium, and potassium. Avocados also contain fiber, protein and several beneficial phytochemicals such as beta-sitosterol, glutathione and lutein, which may protect against various disease and illness. Moreover, the avocado is one of the high calorie fruits that you could be eating. This is due to its larger amounts of fat content, approximately 20 times the average of other fruits. Here are 10 health benefits of avocados: · Maintain a healthy heart: Avocado contains vitamin B6 and folic acid, which helps regulate homocysteine levels. High level of homocysteine is associated with an increased risk of heart disease. Avocado also contains vitamin E, glutathione, and monounsaturated fat, which help in maintaining a healthy heart. · Lower cholesterol levels: Avocados are rich in a compound called beta-sitosterol which has been shown to be effective in lowering blood cholesterol levels. · Control blood pressure: Avocados are also a great source of potassium, which helps in controlling blood pressure levels. · Anti-Inflammatory properties: Phytonutrient compound found in avocados, such as polyphenols and flavonoids have been found to have anti- inflammatory properties, thereby reducing the risk of inflammatory and degenerative disorders. · Promote eye health: Avocado is an excellent source of carotenoid lutein, which is known to help protect against age-related macular degeneration and cataracts. · Regulate the blood sugar levels: The monounsaturated (good) fats in avocados can reverse insulin resistance which helps to regulate blood sugar levels. Avocados also contain soluble fibers which keep steady blood sugar levels. · Prevent birth defects: Avocados are rich in folate, a B vitamin commonly known as folic acid. One cup of avocado provides about 23% of the recommended daily value of folate. The high amount of folate in avocado is essential in the prevention of birth defects, such as neural tube defect and spina bifida. · Anti-aging properties: Being rich in antioxidants, avocado is beneficial in preventing aging symptoms. The glutathione in avocado may boost immune systems, slows aging process, and encourages a healthy nervous system. · Cure bad breath: Avocados are one of the best natural mouth washes and bad breath remedies. They cleanse the intestine which is the real cause of coated tongue and bad breath. 53 · Weight gain: The avocado has 200 calories for 100 grams. Typically, fruits have approximately 60-80 calories for 100 grams. Due to the high amounts of calories, avocado is the best diet for people who want to gain weight. Avocado is a healthy source of calories, unlike many other calorie-dense foods that may contain excess saturated fats and sugar. B=Banana Banana is a perennial herbaceous plant that grows in humid, tropical zones. It is one of the most loved tropical fruit and is thought to be originated in the Southeast Asia. Today, banana is probably one of the most widely cultivated crops in the tropical and subtropical regions. Banana is an economical and versatile fruit that is easy to find in any supermarket around the world. Aside from being inexpensive and delicious, the fruit also provides many important nutrients, such as vitamin A, vitamin B6, vitamin C, magnesium, and potassium, that can help prevent diseases and keep your body healthy. Nutritional Value of Raw Banana Apart from that, banana is also rich in fiber content and natural sugars, like sucrose, fructose, and glucose, making it a great source of energy and easily digested fruit. Here are 10 health benefits of banana: · Allergies: Banana is very useful for those who are allergic to certain foods. Unlike other protein foods, which contain amino acids that those people cannot tolerate and may cause allergy. Bananas contain only benign amino-acids which in many cases are not allergic. · Anemia: Being high in iron content, bananas are beneficial in the treatment of anemia. They help stimulate, the production of hemoglobin in the blood. · Constipation and Diarrhea: Bananas are a good remedy for constipation and diarrhea as they can help normalize bowel functions. They also have the ability to change the harmful bacteria in the intestines become the beneficial acidophilic bacilli. · Helps to stop smoking: Nutrients contained in banana such as vitamins A1, B6, B12, C, magnesium, and potassium help withdraw nicotine from the body · Improve Mood: Bananas contain Tryptophan, an essential amino acid which is responsible for the production of Serotonin. Serotonin is a hormone that is known to overcome depression and improve mood. · Improve brain function and keep alertness: Potassium found in the bananas is a good source to improve brain and keep alertness. So add a banana to your breakfast before you start the day. · Kidney Disorders: Being of their low protein and salt and high carbohydrate content, bananas are valuable in kidney disorder. They are useful in uremia, a toxic condition of the blood die to kidney congestion and dysfunction. In such cases, a diet of banana should only be taken for 3 to 4 days with consuming 8 to 9 banana a day. This diet is suitable for all kidney problems, including nephritis. · Menstrual disorders: Cooked banana flower and eat with curd is considered an effective medicine for cure menstrual disorders like excessive bleeding and painful menstruation. Banana flower helps increase progesterone hormone which reduces the bleeding. · · Reduce the risk of Heart Attack and Stroke: Bananas are an excellent source of potassium which helps keep body electrolyte and fluids balance in body cells and helps in controlling blood pressure, thus reducing the risk of heart and stroke. Research has shown that regular intake of bananas can reduce the risk of stroke by 40%. Urinary Disorders: Juice from banana stem is well known remedies for urinary disorders. It increases the kidney and liver function, thus reducing discomfort and pain conditions in it. It has been found very helpful to remove stones in the kidney and prostate. Bananas need to be treated with caution because they are easily bruised. 54 C=Cucumber Cucumber (Cucumis sativus) is a vegetable that belongs to the gourd family, Cucurbitaceae, which includes gourds, melons, and squashes. It is one of the oldest cultivated vegetables and is believed to be originated in northern India. Today, cucumbers are the fourth most-widely grown vegetable crop in the world behind tomatoes, onions. Cucumber is often regarded as a healthy food because it is low in calories and fat, and also contains many vitamins and minerals that make them a healthy choice for cooking and snacking. Here are 10 health benefits of cucumber: · Keep body hydrated: Cucumber has 96% water content which helps in keeping the body hydrated and regulating body temperature. · Skin care: The high water content, vitamins A, B & C and the presence of certain minerals like magnesium, potassium, and silica, make cucumbers an essential part of skin care. Ascorbic acid and caffeic acid present in cucumbers can bring down the water retention rate which in turn diminishes the puffiness and swelling under the eyes. Cucumber skin also can bring relief to the skin caused by sunburn or windburn. · Fight cancers: Cucumbers are known to contain lariciresinol, pinoresinol, and secoisolariciresinol – three lignans that have a strong history of research in connection with reduced risk of several cancer types, including breast cancer · Control Blood Pressure: Cucumber juice contains a lot of potassium, magnesium and fiber that work effectively for regulating blood pressure. This makes cucumber good for treating both low blood pressure · Beneficial for teeth and gums: Cucumber juice is also beneficial for people with teeth and gums problems, especially in cases of pyorrhea. Cucumber is a good source of dietary fiber and this fiber massage in the teeth and gums. · Aid digestion: Digestive disorders like acidity, heartburn, gastritis and even ulcers can be cured by the daily consumption of fresh cucumber juice. The high water content and dietary fiber in cucumber are very effective in driving away the toxins from the digestive system and hence aid digestion. Daily consumption of cucumbers can be regarded as a remedy for chronic constipation. · Relieve gout and arthritis pain: Cucumber is rich in vitamin A, B1, B6, C & D, Folate, Calcium, Magnesium, and Potassium, when mixed with carrot juice, they can relieve gout and arthritis pain by lowering the uric acid levels. · Cures diabetes: The cucumber juice has been found to be beneficial for the diabetic patients. This vegetable contains a hormone needed by the cells of the pancreas for producing insulin. · Reduces cholesterol: Researchers found that some compound called sterols in cucumber may help reduce cholesterol levels. · Aid in weight loss: Due to its low calorie and high water content, cucumber is an ideal diet for people who need weight loss. Reference: http://www.healthonlinezine.info Take Responsibility for your Life; continued from pg. 52 We have just one life to live, it has no duplicate. So my dear, we all have to fulfill our individual purposes on time because time waits for no man. The clock is ticking: seconds after seconds, minute after minute, hour after hour, day after day, week after week, month after month and eventually year after year. Life is a flower that brings out its beauty at a time but at some point, it eventually fades away and is taken away by the breeze. Life is a teacher, the more we live, the more we learn. The heights reached by great men were not attained by sudden flight; while their contemporaries were sleeping, they toiled night and day. You are in a vehicle and are set to accomplish a mission. So, don't be distracted, remain focused, grab all good opportunities on your way. You will get there, just move on! “You must have the right kind of attitude because it attracts, just like beautiful flowers attract insects” 55 BY OLADIMEJI MAYOWA The 19-Year Wait When the first AFCON (African Cup of Nations) tournament was hosted by Sudan in 1957, it could be argued that Nigerians knew little about the cup as well as the 23-year wait that was to follow before the country would have her first taste of glory. This was in the year 1980 when the tournament was hosted by Nigeria. Fourteen years from her last triumph, the country was once again in a jubilant mood when the super eagles as the Nigerian senior national men's team are fondly called beat their Zambian counterparts known as the 'chipolopolo'(meaning copper bullets) by two goals to one to lift their second AFCON title on Tunisian soil in the year 1994. Nigerian fans could be pardoned for their ecstasy leading to the 2008 AFCON tournament hosted by Ghana. "Do the math", they told one another; "1980+14=1994, 1994+14=2008". "It's definitely our time for another cup", they enthused. In the Nigerian soccer fans were thrown a lifeline when CAF (Confederation of African Football) decided to shift the nation's cup tournament to odd number years starting from 2013 to prevent AFCON tournaments being held on world cup tournament years which are held on even number years. Qualification for the 2013 AFCON tournament to be held in South Africa was easy with the Nigerian team thrashing their Liberian counterparts by six goals to one at the U. J. Esuene stadium in Calabar. Next up for the team was the camping exercise held in Faro, Portugal which majority of Nigerian soccer fans failed to follow with keen interest. They had already been disappointed for longer than expected. The list for the tournament preceding tournaments leading up to this particular one, since the turn of the millennium, the team had picked up one runners-up medal and three bronze medals. However, the shambolic display of the team at that tournament which was highlighted by crashing out at the quarter final stage to a 10-man Ghanaian team was only soothed slightly by another third place finish at the 2010 edition of the AFCON tournament in Angola. On the 8th of October 2011, Nigerian football was thrown into its darkest period in 26 years when under the guidance of coach Samson Siasia, the country failed to qualify for the 2012 edition of the tournament hosted by Equatorial Guinea and Gabon after drawing the last qualification match with Guinea in Abuja. 56 proper was received with an air of pessimism. Only 6 players had participated in a previous AFCON tournament. "How could he have picked 6 home-based players?” Nigerians asked one another in disbelief. When the first and second matches were played against Burkina Faso and Zambia (the defending champions at the tournament), both ending in 1-1 stalemates, even the die-hard fans of the team had little reason to remain optimistic. "Only the GOD who won Chelsea the 2012 champions league can win Nigeria this cup", the most religious Nigerian fans observed. The favourable results then began to come the team's way along with a marked improvement in the performances of the team starting with the final group game against the Ethopian team which ended in a 2-0 victory in favour of the super eagles. This was followed by a massive 2-1 win over pre-tournament favourites Ivory Coast and a resounding 4-1 win over West African neighbours Mali, a team previously coached by the Nigerian coach at the tournament; Stephen Okechukwu Keshi. The final was against the team that had caused the Nigerian team an upset in its first group game by scoring a late equaliser deep into injury time. However, there was to be no repeat of such performance or result. The Nigerian team emerged victorious on the day with a comfortable 1-0 score line with the only goal of the match scored by Sunday Mba who as fate would have it, was one of the home-based players at the tournament. The final match played on a Sunday, forced creative Nigerian minds into coming up with messages like "Burkina Faso wanted to test us, but we said Mba (which could mean 'no' in Igbo language but also the goal scorer's name) on a Sunday (the other name of the goal scorer)." Sunday the 10th day of February 2013 is remembered as the day the 19-year wait for the super eagles to win the AFCON trophy for the third time in the history of the competition finally came to an end. Now another question presents itself: How many years would we have to wait for a fourth trophy? 2 years? 4 years? 14 years? 19 years? Only time will tell. By Nwanya Somutochukwu Sullivan Radio-active Students; continued from pg. 51 Moreover, every nuclear reaction results in the release of enormous amount of energy. We had been pushed to the wall by these neutrons and its likes. It was high time we bragged with our resultant nuclear energy. Like a negative feedback mechanism. Gold obtains its lustrous, expensive and shiny appearance after series of refining and melting processes. Prior to purification, it looks ugly, unpleasant and waste-bound. At refining, it is melted, beaten, expanded, contracted, and pierced and so on. But it emerges in the end to be one of the world's most expensive metals. For me, part one pharmacy class involved a series of bombardment principles and refining policies. We became radioactive as time went on. Subsequently, our nuclear energy became ineffable, insurmountable, inevitable, unfathomable and indescribable. The world needs us and cannot but requires our knowledge. In every part one pharmacy student is a pharmaceutical company, a general hospital, a health minister, a managing director, an entrepreneur and so on. It all starts from the ever green part one pharmacy class. Then the entire journey… after which we become refined, renewed, reformed, prepared and good to go in the profession. Despite the tasks, the adventure, the smooth and turbulent times, we will all emerge as active as therapeutically active drugs. Remember that master question? Good. The answer is yes! Why? We are the radioactive students. In a nutshell, the journey may have been rough, crooked and unpleasant, looking like God has left you like the electromeric electron shift, probably because you could only see a couple of footsteps behind as you went; God will always carry you... Just recognize this fact and trust Him. To everyone I'm associated with, more neurons to your brains. I wish you all the best in every in-course and exam; 57 Awiligwe Arinze O. Much ADo About FASHION 58 FASHION It is believed that the school of pharmacy is not the ideal stage for expressing one's love or craze for fashion, with the strict dress code constraints and the level of professionalism expected that all students exude, some students however have managed to find a way. There has been a not-too-recent explosion in the population of students with body piercings and/or tattoos. Now hold on, I don't have a problem with a couple of ear piercings and 'subtle' tattoos, subtle being the key word, but there is a need to remind ourselves that as much as individuality and personal style is applauded, celebrated even and admired, we, pharmacists, remain professionals and no patient/customer/employer of labor will trust a pharmacist with an eyebrow or lip piercing or a skull, dragon or even a sparrow tattoo to be exactly that; a professional. There are also some trends that are sometimes unavoidable, (SOMETIMES!!!), with the dress code policy of the school of pharmacy. Permit me to refer to them as the VPLs. The Visible Panty Lines for the ladies and the Visible Phallus Lines for men. Unfortunately, and regrettably so, there is no side stepping these issues. They are real and we encounter them almost every day! The VPLs are horrid, offensive, distracting and inappropriate. They make the, obviously unwilling, observer harbor unclean and offensive thoughts which are not just grossly distracting but can be the early roots of a sexual offense/scandal just waiting to happen. The Visible Panty Lines occur mostly as a result of ill-fitting under wears, wearing tight fitting clothes also go a long way in increasing their visibility. Now, since I don't want to appear obstinate by critiquing and not providing a remedy. Ladies, here's how you avoid a VPL. One, get your proper fit when shopping for your under wears, avoiding as much as possible those with elastic bands. Two, get clothes in your correct size, not the size you aspire to be. Three, if you must indeed wear tight fitting clothes, get the appropriate under wears for such apparels. The Visible Phallus Lines, on the other hand, are caused by a lack of underwear, a lack of good underwear or wearing of boxers. So gentlemen, here's how you avoid a VPL. One, invest in briefs. It is understandable that you would want more….room but like bras, they have a job, to hold it all together. Permit them to do their jobs. Two, avoid tight fitting trousers (AKA mosquito trousers as my dear Dean aptly named them) Three, if you must be fashion forward with tighter trousers, make then chinos. Don't get it wrong though, this piece is primarily a fashion rant. Yes, it discusses issues we come across on probably a daily basis in our schools of pharmacy, or at least in my school, but no, it is not an exclusive guide on how you can or cannot or should or should not express yourself as you see fit AND appropriate. To each his own! 59 Funny and Interesting Facts BY KENE' KINGSLEY 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. If you ate too many carrots, you'd turn to orange 19. It would take 120,000,000 mosquitoes, each sucking once, to completely drain the average human of blood. 20. Bamboo can grow up to 3ft in 24 hours 21. American Airlines saved $40,000 in 1987 by eliminating one olive from each salad served in first class 22. Our eyes are always the same from birth, but our ears and nose never stop growing. 23. The cockroach is the fastest animal on 6 legs, covering a meter in one second. 24. Google, with a brand value of $86 billion, is the world's most powerful brand 25. A person can live without food for about a month, but only a week without water. If the water in your body is reduced by 1%, you'll feel thirsty. If it's reduced by 10%, you'll die. 26. A normal person laughs about five times a day 27. By age 60, most people have lost half of their taste buds 28. Humans use 14 muscles to smile, and 43 muscles to frown 29. Guinea pigs and rabbits don't sweat 30. On average, dogs have better eyesight than humans, although not as colorful. It is impossible to lick your elbow A crocodile can't stick its tongue out A shrimp's heart is in its head People say “Bless You” when you sneeze because when you sneeze, your heart stops for a milli-second It is physically impossible for pigs to look up to the sky Rats and Horses can't vomit If you sneeze too hard, you can fracture a rib If you try to suppress a sneeze, you can rupture a blood vessel in your head or neck, and die If you keep your eyes wide open when you sneeze, you can pop an eyeball out. Most lipsticks contain fish scales Like fingerprints, everyone's tongue print is different The Grammy Awards were introduced to counter the threat of rock music. Vodka , in Russian means “little water” During an interview, when Adele was asked about her weight, she replied “I don't make music for eyes, I make music for ears” Bruce Lee was so fast that they actually had to slow a film down so you could see his moves. That's the opposite of the norm Tiger sharks embryos fight each other in their mother's womb. The last survivor is born 111,111,111*111,111,111 = 12345678987654321 60 POEMS Remind yourself Remind yourself of the reason you live, of what you want the outcome to be like, of how you want to attain your goals. Remind yourself of the things you said, things that you desired; do you still desire them? Remind yourself of what you have gone through, do you want it to be in vain? Remind yourself of who you are, where you are and where you are going. Remind yourself of YOU because all the answers are in YOU. -ELIZABETH My apology Roses are red plus blood is the same; if your heart feels dreads then I deserve the blame. If chilliness is from rain then death is the same, if your heart feels pain then I deserve the blame. If coldness is from wetness then your tears are the same, because my heart bears witness that I deserve the blame. If anxiety causes you heartache then my depression is the same, of your suffering I must partake because I know I deserve the blame. If my apologies are sincere then your forgiveness should be the same, because I still hold you dear so please take away the blame -VICTOR MONDAY The Pharmacy Student The life of the pharmacy student is one so challenging and to add to that time demanding. He is so busy preparing, compounding and dispensing, In fact he is expected to know all aspects of his discipline. Prescription in Latin he decodes and their dosage forms he records, His best friend is his codex and at the back he finds so useful the index. Information on preparations it buttresses and their side effects it addresses. The lab practical are a whole new experience and for some menace, Classes are compulsory and attendance is mandatory, late night reading is a part of life, Reading 20 pages a day is essential to avoid strife. But all hope is not lost for in God I trust and my course I fancy, So I welcome you to the faculty of pharmacy! VICTOR MONDAY JOKES Joke 1 A man had a pet centipede. He said, “centipede, go get the paper and make it snappy!” A half an hour later, the man went outside and said, “I thought I told you to get the paper a half an hour ago!” “Well, I had to put on my shoes,” said the centipede. Joke 2 A man was looking out of his window when he noticed that there was a snail on one of his plants. So, he took the snail and threw it as far as he could. Ten years later, the old man heard a tap tap on his window, and when he looked up, he saw a very cross snail which looked at him and said, “hey, what did you do that for?” 61 Joke 3 Three sons left home to make their fortunes, and they all did very well for themselves. They got together recently and were discussing what they each had done to benefit their aged mother. “Well,” said the first one, “I bought Mom a huge house in Banana Island.” “I bought her a Toyota Avensis and hired a full-time driver for her,” said the second. “I've got you both beaten,” said the third, “I bought her a miraculous parrot that can recite any Bible verse you tell it to.” A little later, the mother sent out a thank you letter to all the three sons. “Scott-the house you bought was too big. I only live in one room, but I have to clean the entire house. Michael-the car is useless because I don't go anywhere because I'm too old. But Charles-you know exactly what I like. The chicken was so delicious.” RIDDLES Q. Who comes to a picnic but is never invited? A. Ant. Q. What letter can hurt you if it gets too close? A. B (bee). Q. Why did the fly never land on the computer? A. He was afraid of the world wide web. Q. Why are As like flowers? A. Because bees come after them. Q. What do you call a fly without wings? A. A walk. Q. What creature is smarter than a talking parrot? A. A spelling bee. Q. What is on the ground and also a hundred feet in the air? A. A centipede on its back. Q. What do you call two ants that run away to get married? A. Ant-elopes. Q. What does the dog say to the flea? A. Stop bugging me. Q. What do frogs order when they go to a restaurant? A. French Flies. 62 63 64