Caninsulin® VetPen® - Managing diabetes mellitus in dogs and cats

Transcription

Redefining pet diabetes management
Reference guide for managing pet diabetes and
Caninsulin VetPen
®
FPO short cut die line
®
This page is intentionally left blank
• About diabetes
About
diabetes
• About diabetes
Page title: Diabetic pets can live long, happy lives.
•
It may be difficult to accept that your pet has diabetes, but it doesn’t have to reduce your pet’s quality of life.
•
Having your pet properly diagnosed is the first step in successfully managing this condition.
•
There are hundreds of thousands of diabetic pets living active lifestyles every day.
•
Your pet’s diabetes will need to be managed through a combination of insulin injections, diet, and exercise.
• About diabetes
Diabetic pets can live long,
happy lives.
• As it is with human diabetics, your pet’s diabetes
can be managed successfully through:
• Insulin injections
• Diet
• Exercise
• About diabetes
Page title: What is diabetes?
•
Diabetes mellitus is a condition caused by a lack of insulin, a hormone made by the pancreas.
•
Insulin is needed to allow cells to use glucose, a sugar, for energy.
•
T he lack of insulin is a primary cause of glucose building up in the blood, which leads to signs
associated with diabetes.
• About diabetes
What is diabetes?
Lack of
insulin
Glucose
cannot
be used
by cells for
energy
Glucose
builds
up in the
blood
Leads
to signs
associated
with diabetes
• About diabetes
Page title: What happens in a non-diabetic pet.
•
The pet’s food is converted into glucose.
•
Glucose travels through the bloodstream to cells throughout the body.
•
Insulin allows glucose to enter cells where it is used as fuel.
•
This is the same process that occurs in the human body.
• About diabetes
What happens
in a non-diabetic pet.
• About diabetes
Page title: What happens in a diabetic pet.
•
Glucose is unable to enter the cells.
•
Some common reasons for this are:
• The pancreas does not produce enough insulin. (This occurs in type 1 diabetes—most common in dogs.)
• The body’s cells build up a resistance to insulin, making it more difficult for cells to get the glucose they
need for energy. (This occurs in type 2 diabetes—most common in cats.)
•
Glucose builds up in the bloodstream and leads to signs associated with diabetes.
• About diabetes
What happens
in a diabetic pet.
As in humans, there is more than one type of diabetes in pets:
• Type 1 diabetes— what most dogs get
• T
ype 2 diabetes— what most cats get
• About diabetes
Page title: How injected insulin helps manage your pet’s diabetes.
•
o matter what type of diabetes your pet might have, insulin injections
N
can help manage your pet’s diabetes.
•
By providing insulin, glucose can enter cells and blood glucose levels are reduced.
•
As a result, cells get the fuel they need.
• About diabetes
How injected insulin helps
manage your pet’s diabetes.
Well-regulated pets show few or no signs of diabetes.
• About diabetes
Page title: How we know the insulin is working.
•
If insulin is sufficiently lowering your pet’s blood glucose level, the first signs you will notice is a decrease
in your pet’s thirst and need to urinate.
•
e may also perform what is called a blood glucose curve, which is a measurement of your pet’s glucose
W
levels over a 9- to 24 - hour period.
•
This may be required a few times until an effective dose is determined.
•
Our goal is to ensure that the insulin dose given is effectively regulating your pet’s glucose levels.
•
nce this is accomplished, your pet’s diabetes signs should be minimal or disappear and ongoing dosing
O
and maintenance will be minimal.
• About diabetes
How we know the
insulin is working.
Pets receiving insulin therapy once or twice daily (insulin injected at time = 0)
Well-regulated dog (once-daily dose)
Well-regulated cat (twice-daily dose)
450
25.0
22.2
400
22.2
350
19.4
350
19.4
300
16.7
300
16.7
250
13.9
250
13.9
200
11.1
200
11.1
150
8.3
150
8.3
100
5.6
100
5.6
50
2.8
50
2.8
0
0.0
2
4
6
8
10
12
14 16
18
20
22
24
Time in Hours
Insulin response curve
0
2
4
6
8
10
12
14 16
18
20
22
0.0
24
Time in Hours
Blood Glucose Concentration (mg/dL)
25.0
400
450
22.2
350
19.4
300
16.7
250
13.9
200
11.1
150
8.3
100
5.6
50
2.8
0
0.0
1
2
3
4
5
6
7
8
9
10
11
12
Time in Hours
Blood Glucose Concentration (mmol/L)
25.0
400
450
Poorly regulated pet
• About diabetes
Page title: Giving your pet a happy, healthy life may cost less than you think.
•
Insulin therapy helps reduce the signs of diabetes and allows your pet to regain a healthy, active lifestyle.
•
nce your pet is successfully regulated, the cost of these invaluable benefits may be as little as a daily
O
cup of coffee. [Needs local review: costs of insulin and coffee may vary]
• About diabetes
Giving your pet a happy, healthy life
may cost less than you think.
Once your pet is regulated,
the cost of managing your pet’s diabetes
can be as little as a daily cup of coffee.
[Needs local review: costs of insulin and coffee may vary]
• About diabetes
Page title: VetPen® helps make it easier to manage your pet’s diabetes.
Offering the convenience that insulin pens have brought to human diabetics, VetPen:
•
Is more convenient to use than insulin syringes
• The ergonomic design of VetPen makes it easier to give your pet insulin injections discreetly anywhere,
without the hassle of dealing with vials and syringes.
•
Delivers an accurate dose consistently
• You will be able to provide an accurate dose every time with just the turn of the dial. And VetPen
has been shown to enable more accurate dosing than syringes for low and medium insulin doses.1
•
Helps enhance insulin delivery safety
• The all-in-one construction of VetPen, double needle caps, and sharps remover reduce the risk of accidental
needle stick injuries.
•
Takes fewer steps to prepare doses than using syringes
• VetPen contains a multi-dose insulin cartridge that allows you to prepare doses easily, once a new cartridge
has been fully primed for use.
Reference: 1. Burgaud S, Riant S, Piau N. Comparative laboratory evaluation of dose delivery using a veterinary insulin pen. In: Proceedings of the WSAVA/
FECAVA/BSAVA congress; 12–15 April 2012; Birmingham, UK. Abstract 121.
• About diabetes
VetPen® helps make it easier
to manage your pet’s diabetes.
VetPen offers the same convenience that insulin pens have brought to human diabetics:
• Is more convenient to use than insulin syringes
• Makes it easier to deliver an accurate dose consistently
• Helps enhance insulin delivery safety
• Takes fewer steps to prepare doses than using syringes
• About diabetes
Page title: Getting to know VetPen®.
•
ose selector —allows you to provide precise doses simply by turning the dial. Doses can be selected in increments
D
of 0.5 units with an 8 IU VetPen and in increments of 1 unit with a 16 IU VetPen.
•
Dose selector adaptor— may be used to provide a better grip when selecting a dose.
•
Release button— used to inject insulin into your pet after inserting the needle through your pet’s skin.
•
I nternal plunger— this is released when you press and hold the release button, which causes insulin to be expelled
through the needle.
•
Release button extension— may be used to provide a better grip when giving injections.
• About diabetes
Getting to know VetPen®.
Dose selector adaptor
Release button extension
Internal plunger
Release button
Dose selector
• About diabetes
Page title: Getting to know VetPen® (cont’d).
•
Insulin cartridge—allows you to administer multiple doses and may be easily changed when empty.
•
artridge plunger— the small red stopper at the end of the cartridge that the internal plunger pushes
C
to expel the selected insulin dose through the needle.
•
Cartridge holder— protects the insulin cartridge from breakage during storage and transit.
•
eedle— Triple-sharpened and specially lubricated to help minimize discomfort for your pet and require
N
less force to penetrate the skin.
• Double needle caps— reduce the risk of accidental needle stick injuries.
•
Protective cap— allows for safer handling.
•
Needle remover— removes used needles, while minimizing the risk of accidental needle stick injuries.
•
etPen cap— protects the insulin cartridge in between injections and allows the device to be carried
V
easily in the travel pouch provided.
• About diabetes
Getting to know VetPen® (cont’d).
Cartridge holder
VetPen cap
Insulin cartridge
Protective cap
Cartridge plunger
Needle
Needle
remover
• Preparing
Caninsulin® VetPen®
Preparing
Caninsulin® VetPen®
• Preparing Caninsulin® VetPen®
Page title: Getting started.
•
First, you need to load an insulin cartridge.
•
Remove the cap and unscrew the body from the cartridge holder (1).
•
The arrow on the VetPen® body should point to the start line.
• If it is not, push the release button.
•
Check to make sure that the internal plunger is fully retracted.
•
If not, rewind the plunger by holding the lower part of the VetPen body between your thumb and finger.
•
Turn the VetPen body gently in a clockwise direction until the plunger is fully retracted (2).
Getting started.
1.
Unscrew VetPen®.
2.
Make sure the internal
plunger is fully retracted.
Page title: Loading a cartridge.
•
Turn the cartridge up and down at least 10 times to mix the insulin.
•
Continue until the insulin is uniformly milky in appearance (1).
• Don’t use the cartridge if the insulin is not uniformly milky after mixing.
•
Load the cartridge (2).
•
Screw the cartridge holder on (3).
Loading a cartridge.
1.
Mix insulin.
2.
Place in cartridge holder.
3.
Screw holder onto pen.
Page title: Priming a new cartridge.
When using a cartridge for the first time, priming is necessary to remove any air bubbles. This is a critical process
because it ensures your pet receives an accurate dose, which is essential for proper regulation.
To prime a new cartridge:
•
Dial a 1-unit test dose.
•
olding the pen vertically with the needle pointing upward, tap the cartridge gently with your finger a few times
H
to push any air bubbles to the top.
•
P ush and hold the release button down towards the needle until the arrow on the pen body points to the
start line on the dose selector.
Repeat these steps until insulin drips actively or squirts out of the needle tip and you do not see any air bubbles
in the cartridge window as you turn VetPen® upside down.
A small amount of insulin may appear at the needle tip before the VetPen is fully primed, but continue the steps
until insulin drips actively or squirts out of the needle tip.
Priming a new cartridge.
1.
2.
Tap cartridge
with your finger.
Be sure to keep the needle pointing upward while removing air bubbles.
Page title: Preparing the VetPen® before each injection.
Preparing VetPen for use consists of 3 key steps:
•
Place a new needle on VetPen.
•
Mix the insulin in VetPen.
•
Ensure the VetPen and the needle are working properly.
It is very important that you perform all 3 steps in the preparation process before every injection
to ensure the VetPen and needle are working properly and your pet receives an accurate dose.
Preparing the VetPen®
before each injection.
Preparing VetPen consists of 3 key steps:
1.
Place a new needle on VetPen.
2.
Mix the insulin in VetPen.
3.
Ensure the VetPen and the needle are working properly.
It is very important to perform all 3 steps in the preparation process before every injection.
Page title: Place a new needle on the VetPen®.
•
Peel protective film off new needle and screw it onto the VetPen (1).
•
Remove the outer protective needle cap (2).
•
Replace the VetPen cap to cover the needle.
•
lways use a new needle with each injection. Failing to do so could
A
cause contamination or blockage of the needle and the needle can
become dull and make the injection less comfortable.
Place a new needle
on the VetPen®.
1.
2.
Screw onto the VetPen.
Always use a new needle for every injection.
Remove outer protective cap
before use.
Page title: Mixing insulin in VetPen®.
•
Replace the VetPen cap to cover the needle.
•
Mix the insulin by turning VetPen up and down at least 10 times.
•
T his step may not be necessary if a new cartridge was just loaded and the insulin
in the cartridge is uniformly milky in appearance.
Mixing the insulin
in VetPen®.
Make sure the VetPen® cap is on prior to mixing to protect the
needle and yourself.
Page title: Ensure VetPen® and needle are working properly.
•
Dial 1 unit dose on the dose selector.
•
olding the VetPen vertically upward, push and hold the release button down towards the needle until
H
the arrow points to the start line.
•
If the VetPen has been primed correctly (air removed from cartridge before first use), insulin should
drip actively or squirt out of the needle tip. If this is the case, you know that the VetPen and the needle
are working properly.
•
Confirm the VetPen dose selector has returned to the start line.
•
The VetPen is now ready for use.
Ensure the VetPen® and needle
are working properly.
•
Dial a 1-unit dose.
•
Push the release button down towards
the needle. Insulin should drip actively
or squirt out of the needle tip.
•
Confirm the dose selector has returned
to the start line.
•
The VetPen is now ready for use.
• Injection
Injection
• Injection
Page title: Dialing a dose.
•
T he simple design of the dose selector on the VetPen® enables you to dial an accurate dose
for your pet consistently.
•
Make sure the arrow points to the start line (1).
•
Turn the dose selector carefully to your pet’s dose (2).
•
It is important to not turn the dose selector back to a lower dose. This can damage or break the
VetPen. If too high a dose has been selected, release the insulin through the needle into a tissue
or swab by pressing the release button. Then select the correct dose.
•
Make sure that the arrow points toward the correct number of units before proceeding.
• Injection
Dialing a dose.
1.
Make sure the arrow
points to the start line.
2.
Turn the dose selector to
your pet’s dose.
Take your time selecting your pet’s dose. It is not possible to turn the
dose selector back to a lower dose as it will damage the VetPen®.
• Injection
Page title: Where to inject your pet.
•
Injections are given under the skin in the area behind the shoulder blade to the middle of your pet’s lower back.
•
To minimize your pet’s discomfort, rotate the injection site.
•
T o keep pets relaxed through the injection process, remain calm. You can also continue to talk and pet him
or her before and during the injection.
•
plate of food or a treat can help distract your pet and will be seen as a reward following the injection.
A
You can also use petting and praise as rewards.
• Injection
Where to
inject your pet.
Rotate the injection site to minimize discomfort for your pet.
• Injection
Page title: Injecting your pet.
•
T he needles used with VetPen have a lubricated coating to minimize discomfort for your pet and are specifically
designed to require less force to penetrate the skin.
•
Ensure all protective needle caps have been removed and insert the needle through the skin.
•
P ress the release button down fully and hold it in place until the arrow points to the start line. This will
happen quickly. Then count slowly to at least 5 to ensure the pet receives a full dose. This time allows
the internal plunger of the VetPen to expel the precise dose selected through the needle.
•
Remove the needle from the skin and praise your pet —you have completed the injection.
• Injection
Injecting your pet.
After the arrow points to the start line, slowly count to at least 5
before removing the needle. Talk to and praise your pet.
• Injection
Page title: Disposing of the needle.
•
To make it easier to remove the needle and avoid injury, VetPen® comes with a needle remover.
•
Simply insert the needle into the needle remover and unscrew it (1).
•
Press the blue button on the needle remover to release the needle (2) into a sharps container.
•
hile a new needle will be needed for the next injection, do not place it on at this time.
W
Instead, just replace the pen cap.
• Injection
Disposing of the needle.
1.
Insert the needle into the
needle remover and unscrew it.
2.
Never store the VetPen® with the needle attached.
Press the blue button on the needle
remover to release the needle.
• Changing a cartridge
Changing a
cartridge
Page title: Changing a cartridge.
•
hen the insulin cartridge is empty or you determine there is not enough insulin left in the cartridge
W
for a full dose, you will need to change the cartridge.
• You can determine how much insulin is left by looking at the markings on the cartridge
holder and the insulin through the cartridge window when you hold the VetPen® with
the needle pointing down.
•
First, make sure the needle has been removed to avoid injury.
•
Unscrew the cartridge holder and remove the cartridge (1).
•
olding the white part of the pen between your thumb and finger, gently turn the body clockwise
H
until the internal plunger is fully retracted (2).
•
Load a new cartridge as shown before.
1.
Unscrew the cartridge holder
and remove the cartridge.
2.
Gently turn the body clockwise until
the internal plunger is fully retracted.
• Storage and cleaning
Storage and
cleaning
Page title: Storing and cleaning VetPen®.
•
Store insulin cartridges in the refrigerator.
•
nce in the VetPen, cartridges do not need to be refrigerated. Store at room temperature,
O
no higher than 25°C (77°F). [Needs local review.]
•
Protect from light.
•
Do not freeze.
•
VetPen should always be stored or carried with the pen cap on and no needle attached.
•
To clean, wipe with a damp cloth.
• Do not immerse in water.
Storing and cleaning VetPen®
• Store insulin cartridges in the refrigerator.
• Cartridges in the VetPen do not need to be refrigerated. [Needs local review.]
• Protect from light.
• Do not freeze.
• VetPen should always be stored or carried with the pen cap on and no needle attached.
• To clean, wipe with a damp cloth.
• Do not immerse in water.
Page title: Take VetPen® with you.
•
VetPen starter kit includes a travel pouch for when you are away from home.
•
T he travel pouch holds the VetPen, needles, needle remover, and insulin. Remember,
extra insulin cartridges not primed in the VetPen need to be kept refrigerated. [Needs local review.]
Take VetPen® with you.
Travel pouch included.
Page title: Resources
•
For full instructions, see Caninsulin® VetPen Instructions for Use.
•
For more information on Caninsulin VetPen and pet diabetes, visit www.caninsulin.com.
Resources
•
For full instructions, see the
Caninsulin® VetPen® Instructions for Use.
•
For more information on Caninsulin VetPen
and pet diabetes, visit www.caninsulin.com.
• Troubleshooting
Troubleshooting
• Troubleshooting
Page title: Troubleshooting always starts with making sure the cartridge was primed properly.
If you encounter any problem using VetPen®, the first step to resolving the problem is always
to confirm that air was properly removed from a new cartridge through priming.
If you do not prime a new cartridge properly, remaining air bubbles can create multiple issues that
result in your pet receiving too much or too little insulin.
To properly prime a cartridge:
•
•
olding the VetPen with the needle pointing vertically upward, tap the cartridge with your
H
finger a few times to push any air bubbles to the top.
•
Push and hold the release button until the arrow points to the start line on the dose selector.
•
epeat these steps until insulin drips actively or squirts out of the needle tip and you no longer
R
see any air bubbles in the cartridge window as you turn VetPen upside down.
• Troubleshooting
Troubleshooting always starts
with making sure the cartridge
was primed properly.
To prime a cartridge:
•
•
Tap the cartridge with your finger a few times.
•
Push the release button until the arrow points
to the start line on the dose selector.
•
Repeat if necessary.
• Troubleshooting
Page title: 1: Insulin drips actively from the needle after injection.
•
If air bubbles have been removed from the cartridge and VetPen has been prepared for use,
insulin dripping actively from the needle could be a sign that the needle has been removed
too quickly.
•
If this occurs, do not give the pet another dose.
•
Be sure to:
• During injection, push the release button down fully and hold it until the arrow points to the
start line on the dose selector.
• Slowly count to at least 5 after the dial has returned to the start line before removing the needle.
• This ensures a complete dose is delivered.
• Troubleshooting
1
Insulin drips actively from the needle after injection.
This may be a sign that:
•
The needle may have been removed before the injection was completed.
Be sure to:
•
Push the release button down fully and hold it until the arrow
points to the start line.
•
Slowly count to 5 after the dial has returned to the start line
before removing the needle.
• Troubleshooting
Page title: 2: Dose selector does not return to the start line.
There are 4 things you can do to help avoid this from happening:
•
Push the release button down fully toward the needle until the dose selector is released.
•
Make sure your hand does not interfere with the movement of the dose selector.
•
lways use a new needle for each injection and change it if you experience problems.
A
The needle can become blocked if reused and is designed for single use only.
•
Check to make sure there is enough insulin in the cartridge to complete the injection.
• Troubleshooting
Dose selector does not return
to the start line.
2
Possible causes:
•
The release button was not pushed down fully.
•
Your hand restricted the movement of the dose selector.
•
The needle is blocked.
•
There is not enough insulin in the cartridge.
• Troubleshooting
Page title: 3: Not enough insulin in the cartridge to complete an injection.
•
You may need to give the pet the remainder of its dose.
•
Write down the number where the dose selector stopped.
• This is the number of units that have not been administered.
•
P ut in a new cartridge, prime the VetPen® (remove air bubbles from cartridge),
and prepare for use.
•
Turn the dose selector to the number you wrote down and inject the pet as usual.
• Troubleshooting
3
Not enough insulin in the cartridge
to complete an injection.
•
You may need to give your pet the remainder of its dose.
•
Write down the number where the dose selector stopped.
•
Put in a new cartridge, prime the VetPen®, and prepare for use.
•
Turn the dose selector to the number you wrote down and inject your pet.
• Troubleshooting
Page title: 4: No insulin drips actively or squirts from the needle after priming or preparing for use.
Reason 1: The needle is blocked.
•
To fix, remove the needle attached to the VetPen® and replace it with a new one.
•
Remember, use a new needle for each injection. The needle is designed for single use only.
• Troubleshooting
No insulin drips actively or squirts from the
needle after priming or preparing for use.
4
Reason 1:
Needle may be blocked.
• Remove the needle and replace it with a new one.
• Remember, use a new needle for each injection. The needle is designed
for single use only.
• Troubleshooting
Page title: 4: No insulin drips actively or squirts from the needle after priming or preparing for use (cont’d).
•
Reason 2: The cartridge plunger may be stuck.
•
How to fix:
• Place the protective cap back onto the needle and unscrew the cartridge holder.
• Slide the release button towards the internal plunger and hold it until the arrow points to the start line.
• Dial 2 units without screwing the device back together.
• Push and hold down the release button until the arrow points to the start line.
• Without rewinding the internal plunger, screw the cartridge holder and the VetPen body back together.
This should release the cartridge plunger and expel some of the insulin.
• Troubleshooting
No insulin drips actively or squirts from the needle
after priming or preparing for use (cont’d).
4
Reason 2:
The cartridge plunger may be stuck.
• How to fix:
• Remove cartridge holder.
• Dial 2 units.
• Screw cartridge holder back on.
• Troubleshooting
Page title: Resources
If you experience any difficulties while using VetPen®,
please feel free to ask questions or visit www.caninsulin.com.
•
For full instructions, see Caninsulin® VetPen Instructions for Use.
•
For more information on Caninsulin VetPen and pet diabetes, visit www.caninsulin.com.
• Troubleshooting
Resources
For additional information
and support on using VetPen®:
•
Talk to your veterinarian
•
For full instructions, see the Caninsulin® VetPen
Instructions for Use.
•
For more information on Caninsulin VetPen and pet
diabetes, visit www.caninsulin.com.
Copyright © 2013 Intervet International B.V., a subsidiary of Merck & Co., Inc.
All rights reserved.
2013_MAH_CA_027

Caninsulin® VetPen® - Managing diabetes mellitus in dogs and cats

Transcription

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