Balchem`s SHURE Technology for Ruminants

Balchem’s SHURE
Technology for
Ruminants
Balchem’s SHURE Technology is based on a proprietary microencapsulation
process that provides targeted nutrient delivery to the small intestine of
ruminants. In simple terms, the microencapsulate is a substrate coated with
another material to form a granular powder. In this case, a nutrient is coated
with Balchem’s proprietary lipid-based materials, all of which are GRAS and
approved for use as a feed additive.
There are a number of approaches to producing a microencapsulated nutrient
and so the resulting microencapsulate can have a wide range of performance
characteristics. The product’s functionality is highly dependent on the
microencapsulation process as well as the coating materials used. For high
performance microencapsulates, in addition to consistent product properties, the
coating needs to provides three important functions:
About Balchem
For more than 40 years, Balchem has perfected
the art of delivering nutrients to specific locations
under many different environmental conditions.
Today this technology protects more than 140
different products across human, animal and
industrial applications.
Protect your entire nutrient investment with Shure
Technology from Balchem.
1.STABILITY
2.PROTECTION
3.BIOAVAILABILITY
The microencapsulate needs to provide STABILITY of the nutrient during storage,
for example in a moist feed and at adverse temperature ranges. When consumed
by the ruminant, it needs to PROTECT the nutrient from degradation by rumen
microbes, and thirdly, the coating needs to release the nutrient for absorption in
the small intestine, providing high BIOAVAILABILITY.
Is microencapsulation necessary and why do products
need to be “rumen protected”?
Microencapsulation allows for nutrients to be delivered to targeted locations
consistently and efficiently. In the case of ruminants, microencapsulation allows
nutrients to bypass the rumen for delivery to the small intestine. Because the
rumen degrades almost everything it encounters, protecting critical nutrients
through microencapsulation is essential to meet the needs of today’s high
producing dairy cows. A good example of the use of microencapsulation to
protect nutrients from rumen degradation is shown in Figure 1 by comparing
unprotected raw niacin to our NiaShure® microencapsulated niacin product.
After 24 hours of ruminal incubation, 94% of unprotected niacin is broken
Balchem Corporation
52 Sunrise Park Road, New Hampton, NY 10958
Toll-free 800-780-9233, Fax 845-326-5800
E-mail [email protected]
www.Balchem.com
Figure 1. Graph showing the benefits of
encapsulation using Balchem’s encapsulated niacin,
NiaShure, compared to raw niacin on rumen stability.
ReaShure is a trademark of Balchem Corporation ©2011 Balchem Corporation. All rights reserved.
What makes a high performance microencapsulate?
STABILITY - The microencapsulate needs to provide nutrient STABILITY during
transportation and storage. When a microencapsulate is included in a feed for
several weeks, moisture in the feed will slowly migrate through the coating of the
microencapsulate and begin to dissolve the nutrient. This can lead to INSTABILITY
of the nutrient and also result in poor PROTECTION in the rumen. A high quality
encapsulate should provide proven stability under typical storage conditions.
Using Balchem’s SHURE Technology, based on a proprietary microencapsulation
process and patented lipid-based coatings, microencapsulates, such as ReaShure®
where the nutrient is choline chloride, are very STABLE relative to competitive
products (Figure 2). In this example, the % STABILITY is a measure of how much
of the choline chloride is rumen stable, after exposure to these feed conditions
for a period of four weeks.
Particularly for lipid coated microencapsulates, another key important STABILITY
functionality is tolerance to cool (<40F, 4C) and freezing temperatures. Even
when a product is handled and stored properly, in many parts of the world
products will be subjected to environments where freezing and thawing of
products will occur. Under these conditions, lipid-based coatings can undergo
detrimental changes resulting in the development of cracks in the coating
and subsequently will result in poor nutrient STABILITY and poor rumen
PROTECTION. To ensure delivery of the nutrient to the small intestine Balchem’s
proprietary-based lipid encapsulated coatings are designed to withstand freeze/
thaw cycles so that the feed and rumen stability of the products are maintained.
In Figure 3, the detrimental effects on an encapsulated product of a freeze/
thaw cycle are clearly illustrated if the product is not freeze/thaw stable. In this
example, Balchem’s new rumen-protected lysine product, AminoShure®-L, is
able to withstand the rigors of a freeze/thaw cycle without any adverse impact
on the coating while the coating of a competitor’s product, which does not
have freeze/thaw stability, is compromised and results in a much higher rumen
release of the substrate therefore, offering very little rumen PROTECTION.
Figure 4 shows a before and after micrograph that demonstrates the cracks that
can develop when a coating is not designed to be freeze/thaw stable.
Balchem Corporation
52 Sunrise Park Road, New Hampton, NY 10958
Toll-free 800-780-9233, Fax 845-326-5800
E-mail [email protected]
www.Balchem.com
Stability, %
down in the rumen resulting in a 6% rumen bypass value while only 11% of
NiaShure is broken down resulting in an 89% rumen bypass value. Although
rumen microbes can synthesize many nutrients in amounts necessary to meet
maintenance and lower milk production demands, these amounts are generally
not sufficient enough to meet the needs of today’s high producing dairy
cows. Simply feeding large amounts of a nutrient does not ensure a significant
increase in the delivery of that nutrient to the small intestine and this approach
is generally expensive and not environmentally conscientious. Encapsulating
ingredients allows for the nutrient to be effectively delivered to the small
intestine for absorption at a lower cost.
Week Post Mixing
Figure 2. Comparison of stability of commercially
available encapsulated choline products when mixed
with meal type grain mixes (10-12% moisture).
AminoShure®-L
Competitor
Figure 3. Impact of a freeze/thaw cycle on the ability of
AminoShure-L and a competitor’s product to maintain the
stability of their coating and remain rumen-protected.
Figure 4. Figure 4 is a contrast phase electron micrograph of a
competitor’s product demonstrating the cracks that can develop
when a coating is not designed to be freeze/thaw stable.
ReaShure is a trademark of Balchem Corporation ©2011 Balchem Corporation. All rights reserved.
BIOAVAILABILITY – once the encapsulate bypasses the rumen, the coating
needs to be designed to release the nutrient for absorption in the small intestine.
Simply demonstrating rumen stability does not ensure intestinal release and
absorption. Based on proprietary lipid-based coating formulations, Balchem’s
SHURE Technology provides a high level of release. Figure 6 shows the results
of a laboratory simulation of rumen and post-rumen intestinal conditions. The
microencapsulate, in this example AminoShure-L, protects 80% of the lysine from
rumen degradation (20% of the lysine is lost in the rumen). Upon subsequent
exposure to intestinal conditions, the proprietary coating releases 80% of the
lysine, resulting in an overall high BIOAVAILABILITY of 64%. At Balchem, these
laboratory tests have been validated through controlled animal bioavailability
trials and animal performance trials (Figure 6).
Are all encapsulates created equal?
Simply the answer is no. There is a wide variation in performance for
microencapsulates, even when the same coating materials are used. Balchem’s
SHURE Technology is designed to provide the highest levels of STABILITY,
PROTECTION and BIOAVAILABILITY, the leader in ruminant nutrient delivery
(Figure 7).
Technology
Rumen
protection
Intestinal
release
Feed
stability
Freeze
stability
?
?
?
?
In vitro release or rumen bypass %
PROTECTION – When consumed, the coating needs to protect the nutrient for
12 hours and sometimes longer in the rumen. As with feed STABILITY, Balchem’s
Shure Technology offers excellent PROTECTION in the rumen which translates to
products with very high rumen bypass values as is shown in Figure 5 using our
ReaShure microencapsulated choline product.
ReaShure-Balchem
Matrix technologyUS distributor in Italy
Choline in a calcium
salt of fatty acidUS manufactured
Figure 5. Graph showing the consistently low in vitro release
and high rumen bypass value of ReaShure choline compared
to competitor products.
Balchem
Alternative
Technologies
Figure 7. Benefits of Balchem encapsulation technology compared to our competitors.
Figure 6. Performance results from a published research trial
feeding AminoShure-L to lactating dairy cows.
Balchem Corporation
52 Sunrise Park Road, New Hampton, NY 10958
Toll-free 800-780-9233, Fax 845-326-5800
E-mail [email protected]
www.Balchem.com
ReaShure is a trademark of Balchem Corporation ©2011 Balchem Corporation. All rights reserved.
A. Matrix technology US distributor
manufactured in Italy
Balchem’s SHURE Technology proprietary
microencapsulation process.
The process is superior to other microencapsulation techniques in providing
excellent barrier properties to water. This translates to excellent STABILITY
and PROTECTION in the rumen. In addition, through Balchem’s proprietary
lipid-based coating technology, the microencapsulates are designed to be
STABLE under cool and freezing conditions and have high release in the small
intestine resulting in high BIOAVAILABILITY. Micrographs taken of Balchem’s
SHURE Technology coating compared to competitor technology are shown in
Figure 8 and demonstrate the consistency of Balchem’s coating process. As is
demonstrated in Figure 9, Balchem’s encapsulation technology withstands the
rigors of everyday mixing when included in a mineral mix and mixed for different
periods of time. In this study, AminoShure-L maintained its high level of rumen
bypass and intestinal digestibility.
No protective barrier with matrix technology.
B. Balchem’s SHURE Technology proprietary
microencapsulation process
Why is Balchem the leader in microencapsulation
technology?
Balchem utilizes over 40 years of microencapsulation experience to engineer
coatings that can deliver a variety of ingredients to targeted locations under
many different environmental situations that have helped meet today’s
nutritional needs of both humans and animals. Balchem’s SHURE Technology,
based on proprietary processes and coating materials, has been extensively
researched and developed over many years, to provide the highest levels of
nutrient STABILITY, PROTECTION and BIOAVAILABILITY to ruminants. All of our
products are thoroughly validated before they are brought to market, supported
by animal data. We continue to conduct research on our products striving to
continually improve upon the technology we have and to help our customers
more effectively utilize our products. Products such as AminoShure-L, for
example, have been evaluated both in the lab and in animals to determine their
bioavailability and their production responses.
In addition, Balchem operates a rigorous quality control program to ensure that all
of our products provide the end-user with the performance and consistency they
require. Each batch undergoes a series of QC tests, which includes nutrient activity
and a measure of STABILITY and PROTECTION. Our manufacturing plants operate
at the high end of leading industry standards, which include US GMP’s and EU
FEAMA and FAMI-QS.
Multiple protective lipid layers ensuring
superior protection.
Figure 8. Different coating technologies
Mineral Mix Sample
5-hr Release (%)
4 min mix
14.3
6 min mix
11.2
8 min mix
13.2
10 min mix
13.7
Base Mix Formula
% By Weight
Limestone
37.8
Sodium bicarbonate
35.9
Aminoshure®-L
12.3
Magnesium oxide
7.6
Monocalcium phosphate
5.2
VTM
1.3
Total
100
Figure 9. Results of a mineral mixing study conducted on
AminoShure-L demonstrating the stability of coating when
mixed for different periods of time in a mineral mix.
Balchem Corporation
52 Sunrise Park Road, New Hampton, NY 10958
Toll-free 800-780-9233, Fax 845-326-5800
E-mail [email protected]
www.Balchem.com
ReaShure is a trademark of Balchem Corporation ©2011 Balchem Corporation. All rights reserved. 022811SHURETECH_V3