ZIAUDDIN MEDICAL UNIVERSITY
Transcription
ZIAUDDIN MEDICAL UNIVERSITY
FACULTY ISSUED BY: REGISTRARS OFFICE, NOVEMBER 2015 5 6 FIRST YEAR SEMESTER 1 |NOVEMBER 2015 - APRIL 2016| 2015-16/01/D.A.M Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 CONTENTS S. No. Page 1. Introduction 1 2. Learning Methods 3 3. Examination Rules 7 4. Test Administration Rules & Regulations 10 5. Whom to Contact 14 6. Management 15 7. Competencies of a ZU graduate 16 8. Patient Safety 16 9. Course Objectives & Strategies Module – 1 Introduction to Medical Sciences 17 Use of Learning Resource Center 17 Study Skills 18 Human Body & Anatomical Terms 20 General Embryology 21 Community Health & Development 23 General Biochemistry 24 General Pharmacology 26 General Pathology 28 Module – 2 Cell Biology and Genetics 31 Module – 3 Basic Biostatistics 39 Module – 4 Cardiovascular Systems 41 Learning Resources 49 10. Student Code of Conduct 52 11. Schedule 59 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 INTRODUCTION Why Study Guide? To inform students how student-learning programme has been organized semester wise, and how it would be implemented. To help students organize and manage their studies throughout the year. What is a Study Guide Book ? (Figure selected from AMEE Medical Education Guide #16) The Guide provides: Information on organization and management of the semester. This will help you to contact the right individual in case you have any difficulty. A description of the module objectives which you will be expected to achieve at the end of each module. Information on learning methods that you will experience during the module. The methods include: Problem-Based Learning (PBL), tutorials (SG), lectures, skills/ practicals and field visits. These learning methods should help you achieve the module objectives. A description of the learning resources available for the Semesters. These include: books, Computer Assisted Learning Programmes, videos and others. Information on the contribution of continuous and semester examinations, on your overall performance. Information on the methods of assessment that will be held to determine your achievement of objectives. Information on examination policy, rules and regulations. The Curriculum: It is integrated comprising of system based modules Curriculum organization: Consists of following for each module and generic courses Course No 1 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 Duration of Semester and Modules Objectives of each module Learning Strategies Number of Hours Test Schedule / CAT & Semester. 2 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 LEARNING METHODS The following teaching / learning methods/strategies are used to promote better understanding: Problem Based Learning (PBL) Tutorials -Field Visits -Lectures Hospital Visits -Seminars Practicals -Assignments Computer Assisted Learning Program (CALP) Case- Based Sessions (CBS) Small Group Sessions (SGS) The programme emphasis is on: Problem-Based Learning: This is a small group activity in which the discussion revolves around a real life problem using the Seven Jump process. Students are expected to consult various learning resources to develop better understanding of the subject. Self-Directed Study: Students may achieve the Objectives by assuming responsibilities of their own learning. How? By sharing and discussing with peers, working individually, seeking information from Learning Resource Center, teachers and resource persons within and outside the college. This is possible by utilizing scheduled self -study period in college, and time outside the college. Community-Based Learning Activities: This takes place within a community including homes of individuals, families, and a variety of health service settings. Family assignment is an integral component of this activity. The Department of Family Medicine monitors students’ activity, and provide constructive feedback. PROBLEM-BASED LEARNING (PBL): WHAT IS IT? • It is a method of learning in which learners (students) in small groups first encounter a problem, which are close to real life situations. The problem is generally discussed in two sessions. • First Session: Learners in small groups, using existing knowledge, discuss (in the presence of a tutor) and list what they do not know or are not sure of, about the problem. The list is known as learning issues (goals). 3 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 • Self Study: Learners have approximately three days time to report. During this time, learners search for new information required to achieve the learning goals listed. In this process, learners are encouraged to consult various learning resources in addition to the textbooks. This does not require a tutor. • Second Session: Learners discuss learning issues and application of acquired knowledge to the problem and summarize by integrating prior and new knowledge in understanding the problem. 4 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 EXAMPLE OF PBL SCENARIO: A 1½ year old male was brought to the OPD by his father with complaints of a swelling in the right groin since birth. Birth History: He was born at 34 weeks’ gestation. His birth weight was 2 kg. PHYSICAL EXAMINATION: BP: 100/60mmHg Pulse: 86/min Temp: 98oF R/R: 15/min Local Examination: Left testis is palpable in the scrotum. Right testis could not be palpated in the scrotum. A 1x1 inch oval, firm, non-tender mass was present in the right inguinal region. Lab: Serum testosterone level: 110 ng/dl Ultrasound: Showed an ovoid homogenous medium-level echogenicity within the right inguinal canal. The parent was counseled about the prevalence of the condition. Orchidopexy was advised. Task: Discuss the embryological basis of the development of signs and symptoms in the above case 5 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 PBL PROCESS The JUMP 1 Read the Problem: Clarify terms not known to you in the problem description Seven JUMP 2 Define the problem. Draw up a list of phenomena that need to be explained Jumps JUMP 3 Explain the problem Try to produce as many different explanations for the phenomena as you can think of JUMP 4 Arrange the explanations Proposed in a logical sequence and summarize them JUMP 5 Formulate learning goals: make a list of what you need to study in order to solve the problem JUMP 6 Through individual study, Attempt to fill the gaps in your knowledge JUMP 7 Summarize the Information collected and verify it by applying it to the problem Evaluation 6 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 EXAMINATION RULES • • • • • • • In one academic year there will be two semesters each followed by an examination. At the end of the academic year there will be resit examinations for 1st and 2nd semester courses. A student passing in 1st semester will be allowed to go to 2nd semester. Those failing in courses of 1st semester will also be allowed to join 2nd semester classes but will appear in the resit exam for the required courses held at the end of the academic year. Students failing in the 2nd semester will also appear in the resit exam at the end of the year. Students failing to achieve required aggregate after the resit of 1st or 2nd semester courses / subjects will repeat the year. There will be external examiners in all semester examinations and resits. 2. ASSESSMENT: MOST FREQUENTLY ASKED QUESTIONS (i) CONTINUOUS ASSESSMENT Q. Are tests scheduled throughout both semesters? YES Q. What contribute to continuous assessment in Semesters I and II? • Scheduled test/s for every module during the semester • PBL, assignments, presentations (may not necessarily be all) Q. In tests and semester examinations, what methods are used to assess knowledge and skills? • MCQs: One best/ true false. • Structured cased based viva voice • Practicals and Objective Structured Practical Examinations (OSPE) Q. What is the passing mark or score for tests and semester examinations? • Fifty-five percent (55%). Q. What is the grading system? • Satisfactory (S) 60% and above • Satisfactory Borderline (S*) 55 to 59% • Unsatisfactory Borderline (US*) 50-54% • Unsatisfactory (US) Below 50% • Q. Are the students notified of the marks in tests and semester examinations and receive feedback of their progress? 7 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 Marks are not notified but Results are notified in semesters of S, S*, US, or US* • Students receive feedback on written tests of MCQs. Q. How is the result compiled of Semesters One and Two? • According to duration, and importance, every module may have one to three tests which carry a defined weightage. Test marks are totaled according to the weightage. The following EXAMPLE may help you understand how Continuous Assessment result is compiled. • • Weightage for Continuous Assessment (Sample) Test PBL Total 75% 25% 100% Note: Quizzes etc may be scheduled by individual module Coordinator, which may not contribute towards your aggregate score. Q. Is there a final or annual examination? No • There are two semester examinations for 1st year MBBS – Semester I & II. Q. Are all enrolled students eligible to take the Semester examination? • No Eligibility is determined as follows: Attendance Cont. Assess. Decision 1 ≥ 80% ≥ 45% Eligible for Semester 2 75-80% ≥55% Eligible for Semester 3 60 – 75% ≥35% Eligible for Re-sit 4 <60% Any score Repeats the year* 5 Any value <35% Repeats the year* *Note: To decide about repeating the year cumulative scores for two semesters is considered(Attendance and Continuous Assessment) 8 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 Q. Does continuous assessment has any credit or contributes towards the Semester Examination? • Yes (20%). Q. Who is declared Satisfactory? • Student is declared Pass if, o He/she scores an aggregate of 55% cumulative in each semester. AND o Scores a minimum of 50% in each subject. Note: If student score an aggregate of 55% in the two semesters, but in any individual subject scores <50%, then cumulative score of that subject in both semesters will be considered to declare him satisfactory. Q. What happens if a student is unable to sit for the Semester Examination? • He/she is allowed to take the resit examination which will be considered as second chance. Q .What happens if a student is unable to sit for the Resit Examination? • The student will be allowed to repeat the year provided he/she has cleared at least one semester for that year. If the student has not cleared both the semester and the resits he/she will be asked to withdraw. WITHDRAWAL FROM THE PROGRAM A student of first and second year, will have to withdraw from the program if he/she fails to pass both semester examinations of any year, within 2 years (4 attempts) 9 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 TEST ADMINISTRATION RULES and REGULATIONS GENERAL RULES: All tests /examinations are monitored by the Department of Examination with the support of the College Dean/Principal, faculty and staff. To ensure that the examinations are held according to the standard conditions and that no examinee or group of examinees receives unfair advantage in the examination, Students (examinees) must strictly adhere to / abide by the rules and regulations of the University. IRREGULAR BEHAVIOR Specific examples of irregular behavior include, but are not necessarily limited to the following: 1. Copying answers from another examinee or allowing answers to be copied. 2. Making notes of any kind during an examination. 3. Failure to follow instructions of the staff present in the examination hall. 4. Acts of disruptive behavior such as raising ones voice, talking to others, interrupting the examination process upon entering the examination hall, or during an examination and other similar acts of behavior. 5. During an examination usage of any unauthorized material such as photographic equipment, communication or recording devices, including electronic paging devices and cellular telephones. 6. Altering or misrepresenting examination result, theft or unauthorized possession of examination materials. 7. Memorizing and reproducing examination materials and any unauthorized reproduction by any means and / or dissemination of examination materials. 10 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 8. Looking in the direction of another examinee, passing of written notes, leaving written notes on vacant seats/ desks not occupied by examinees during the examination may be considered as evidence of copying or attempting to copy and a report of such behavior may result in irregular behavior. 9. Sitting for an examination without being eligible for it, impersonating an examinee or engaging a proxy to take the examination. 11 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 TEST ADMINISTRATION RULES AND REGULATIONS Advice for Students: What to do? Students should arrive at the examination hall before scheduled time. Students arriving within 10 minutes after scheduled test time may be admitted only by the approval of head examiner or official of the Department of Examination. Incase a student arrives late, that is, after scheduled time, he / she is not to be admitted. 2. Students should present College Identity Card, and Admit Card for Annual / Resit Examinations. If student/s do not bring the required Identification Card, he / she may not be admitted to the examination. 1. Advice for Students: What NOT to do? 1. Do not bring into the examination hall any personal belongings, including mechanical or electrical devices, backpacks, handbags, books, notes or study guide materials, calculators, digital watches, watches with computer communication and/ or memory capability, electronic paging devices, recording or filming devices, radios, cellular telephones, food and drinks. Only for specified subject/s special instruction will be given on use of calculator for examination. Do not make written notes or record in anyway the contents of an examination. 3. Any notes found will be confiscated and reported for disciplinary action. 2. Do not communicate with, seek aid from, or provide aid to any other examinee during the examination. 5. Once you (students) start taking an examination, you cannot cancel that examination. 4. 6. If the test is completed in less than the time allotted then do not leave without seeking permission from the staff present in the examination hall. No extra time will be allowed if he /she leave the examination hall for any reason. 12 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 WARNING STUDENTS (EXAMINEES) OBSERVED IN ACT/S THAT IS/ARE POSSIBLE VIOLATION OF TEST ADMINISTRATION RULES OR OTHER FORMS OF IRREGULAR BEHAVIOR DURING AN EXAMINATION WILL BE REPORTED TO THE DISCIPLINARY COMMITTEE FOR ACTION. ALL STUDENTS FOUND INVOLVED IN INDISCIPLINARY ACTION IN THE UNIVERSITY PREMISES (INCLUDING SMOKING) WILL BE SUBJECTED TO DISCIPLINARY ACTION WHICH MAY BE IN FORM OF DEDUCTION IN ATTENDANCE FIVE CONSECUTIVE ACADEMIC SESSIONS. DRESS CODE: o WEARING WHITE COAT IS MANDATORY IN ALL CLINICAL AND LAB SESSIONS. o DRESS SHOULD BE DECENT AND FORMAL FOR BOTH BOYS & GIRLS. o SLIPPERS ARE NOT ALLOWED. 13 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 WHOM TO CONTACT? Any queries or difficulties with the schedule, learning strategy should be directed: In the first instance to the individual, teacher or module coordinator and then to Semester In-charge. Contacts: Semester Incharge Dr. Arsalan Manzoor Mughal Dean Ziauddin Medical College Dr. Kamran Hameed. Associate Dean Ziauddin Medical College Dr.Zahida Memon Controller of Examinations Mr. Nadeem Zaffar Registrar: Mr. Mohammad Yousuf Head of Department for Educational Development Dr. Irum Khursheed ZU Literary and Cultural Society Dr. Raza Abbas Head of Quality Enhancement Cell Dr. Arshia Sami 14 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 MANAGEMENT/ ORGANIZATION Semester Incharge: Dr. Arsalan Manzoor Mughal Assistant Professor, Department of Anatomy Course Name Study Skills Introduction to Medical Sciences Cell Biology and Genetics Genetics Cardiovascular System Coordinator Dr. Momal Khan Dr. Iffat Raza Dr. Noman Majeed Dr. Shamim Mushtaq Dr. Mehwish Zafar Other Team Members Dr Shazia Hashmat Dr Fauzia Perveen Dr Lubna Jahnzaib Dr Ali Nawaz Dr Bilal Aheed Dr Rakhi Dr Sabeen Yezdani Dr Jabbar Ahmed Resource Persons: Basic Health Sciences: Anatomy Dr. Nuzhat Hassan Dr. Bushra Waseem Dr. Kevin Borges Dr. Arsalan Manzoor Biochemistry Dr. Saeeda Baig Dr Zil-e-Rubab Dr. Shamim Dr. Bilal Aheed Pathology Pharmacology Prof. Serajuddaula Syed Prof. Qamar Jamal Dr. Fouzia Sheikh Dr. Naila Hadi Dr. Faraz Baig Dr. Najia Prof. Zahida Memon Dr. Samia Pervaiz Dr. Owais Ismail Dr. Shehla Shaheen Family Medicine: Dr. Jawed Usman Dr Bina Fawad Dr Aamir Ms Humera Ansari Dr Shabana Physiology Dr. Syed Touseef Ahmed Dr. Sadaf Fatima Dr. Sofia Amjad Community Health Sciences: Dr. Farah Ahmad Dr. Hassan Danish Educational Development Dr Irum Khursheed Dr Raheela Ali 15 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 COMPETENCIES OF A ZU GRADUATE At Ziauddin University we expect to develop in you the following competencies, a. b. c. d. e. f. g. Provide safe patient care holistically Integrate basic science concepts to clinical situations Communicate effectively Collaborate with other team members Contribute as researcher Practice evidence based medicine Role model professionalism PATIENT SAFETY To enhance the status of ‘Patient Safety’ and prepare students to practice safe health care; a longitudinal theme of Patient Safety has been integrated in the curriculum. WHO Patient safety guide recommends the given 11 topics which will be used to cover a broad range of context in which Patient Safety will be learned throughout the program from first to final year. Topics: 1. What is patient safety? 2. What is a human factor and why is it important to patient safety? 3. Understanding systems and the impact of complexity on patient care 4. Being an effective team player. 5. Understanding and learning from errors. 6. Understanding and managing clinical risk. 7. Introduction to quality improvement methods. 8. Engaging with patients and caregivers. 9. Minimizing infection through improved infection control. 10. Patient safety and invasive procedures. 11. Improving medication safety. 16 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 COURSE NO.: 101 COURSE NAME: USE OF LEARNING RESOURCE CENTER A course designed for students to introduce them towards the use of library/computer independently and effectively as well as use of computer assisted learning programme. Objectives: By the end of the course, the student shall be able to: 1. Use various Data resources and methods of Literature management and searching. 2. Use ZU’s Learning Resource Centre (LRC). 3. Understand the Learning Resource Center’s rules and regulations. Teaching / Learning Strategies S. No STRATEGY HRS. 1 Orientation 1 Visit to Library 2 Total 3 17 Ziauddin University COURSE NO.: COURSE NAME: MBBS 1st Year 2015– 2016 Semester 1 105 STUDY SKILLS This course orients students to the ZU programme with the objective of developing skills to cope with study pressures as well as to function effectively in small group sessions such as problem-based learning. In addition, students will have opportunities to become familiar with the methods of assessment and feedback. Objectives: By the end of the course, the student shall be able to: 1. Develop rapport with peers and faculty to promote student friendly learning environment. 2. Manage learning effectively by utilizing study guidebook with reference to ZU programs and policies, and rules for promotion 3. Identify the key elements of group dynamics essential for learning, in small group sessions. 4. Participate in the ‘Seven Jumps’, the process of Problem Based Learning relevant to the underlying principles of adult learning. 5. Discuss the study pressures and Identify ways of coping with those pressures. 6. Identify ways of effective time management, in order to develop learning skills desirable for medical students. 7. Identify the key elements and importance of communication. 8. Provide feedback or comments on the overall program for quality improvement. 9. Identify the effective ways of taking assistance from student counselors. 10. Discuss how to resolve conflict and manage anger in real life situations. COURSE NO: 105 COURSE NAME: STUDY SKILLS S No TOPICS 1 “Ice-breaking” session 2 Study guidebook task 3 4 5 6 6 7 8 9 STRATEGY SGS SGS ZU policies and programmes Assessment of students, Competence at ZU a- How do we learn? b- Group dynamics Process of PBL Stress management Time management Students Counseling Communication skills 18 HRS. 2 2 SGS Interactive session 2 SGS 3 PBL + introductory lecture Interactive session Interactive session Interactive session Interactive session 6 2 2 2 2 1 Ziauddin University 10 11 MBBS 1st Year 2015– 2016 Semester 1 Importance of feedback Anger Management Interactive session Interactive session Total 1 2 27 COURSE NO.: 107 COURSE NAME: INTRODUCTION TO HUMAN BODY AND ANATOMICAL TERMS. This course enables students to know the organization and structure of human body in general. Objectives By the end of the course, the student will be able to: 1. Describe the different disciplines of anatomy. 2. Discuss the various techniques to study anatomy in the living such as: • Plain and contrast radiographs • Special X-ray techniques like Barium meal and Angiography etc. • Ultrasonography • CT • MRI • Endoscopy 3. Describe the terms of position in relation to anatomical position: i. Anterior / Posterior ii. Ventral / Dorsal iii. Superior / Inferior iv. Caudal / Rostral v. Medial / Lateral vi. Proximal / Distal vii. Palmar / plantar viii. Superficial /Deep 4. Describe the different anatomical planes. 5. Describe the terms of movements at joints: i. Flexion / Extension ii. Abduction / Adduction iii. Lateral rotation / Medial rotation iv. Pronation / Supination v. Plantar flexion / Dorsal flexion vi. Circumduction vii. Eversion / Inversion 6. Introduction to Skeletal system (Bones and Joints) • List the parts of appendicular and axial skeleton. • Enumerate the functions of bone. • Classify bones on the basis of shape, development, region and structure. • Describe general concepts of development and ossification of bones. • List the parts of young bone. 19 Ziauddin University • • • • • MBBS 1st Year 2015– 2016 Semester 1 Explain the blood supply of long bones. Classify joint on the basis of structure, regions and functions. Discuss the characteristics of synovial joints Classify synovial joints on the basis of structure and movement Define dislocation, sprain and inflammation of joints. 7. Introduction to Muscular System: • Classify muscles • Define spasm, paralysis, atrophy and regeneration. 8. Define the following terms: i) Ossification ii) Ligament iii) Aponeurosis iv) Raphe v) Fascia vi) Tendon vii) Synovial sheath viii) Bursa 9. Define the following: i) Arteries ii) Arterioles iii) Capillaries iv) Veins v) Venules vi) Anastomosis vii) Lymphatics 10. Introduction to Nervous System: • Discuss the general organization of nervous system • Classify nervous system on the basis of structure and function • Discuss the general organization of Autonomic Nervous System 11. Define reflex arc and list its components COURSE NO: COURSE NAME: S. No 1. 2. 3. 4. 107 INTRODUCTION TO HUMAN BODY AND ANATOMICAL TERMS Objectives Anatomical position and terms Bone, joint and muscle Ossification, ligament, aponeurosis, raphae, fascia, tendon, synovial sheath and bursa Artery, arteriole, capillary, vein, venule, anastomosis and lymphatic i) Nervous System and its organization ii) Autonomic nervous system iii) Reflex arc and its components Strategy SGS Lecture SGS Lecture SGS 4 2 Total 20 Hours 2 6 2 16 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 COURSE NO.: 204 COURSE NAME: GENERAL EMBRYOLOGY This course provides a broad understanding of the development of human embryo from conception till 8th week along with the development and functions of placenta. It also includes multiple / twin pregnancies and different types of developmental defects with their genetic and environmental causes. Objectives By the end of the course, the student shall be able to: 123456789101112- 131415161718- List male reproductive organs and their functions. Describe the structure of testis and the process of spermatogenesis. List female reproductive organs and their functions. Describe the structure of ovary and uterus and the process of oogenesis and ovulation. Describe the phases of female reproductive cycles. Describe the phases of fertilization. Enumerate the results of fertilization. Describe the steps involved during in vitro fertilization and embryo transfer. Describe cleavage and blastocyst formation. Discuss the results of implantation at abnormal site. Describe the events of the second week of development including: i) Formation of amniotic cavity, amnion, bilaminar embryonic disc, yolk sac, chorionic sac and primary chorionic villi. Describe the following events of the third week of development. i) Formation of primitive streak and notochord ii) Gastrulation iii) Formation of neural tube iv) Formation of somites v) Formation of intra embryonic coelom vi) Formation of blood cells and blood vessels vii) Formation of secondary and tertiary chorionic villi Describe folding of embryo and its results. List the derivatives of germ layers and neural crest cells. Describe the structure, development and functions of placenta and fetal membranes. List the important events of embryonic period from 4th week to 8th week. Describe the types of twin / multiple pregnancies. i) Define teratogenesis. ii) Classify the teratogens. iii) Describe the basic principles of teratogenesis. 21 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 20- Calculate the expected date of delivery (EDD). 21- Describe various methods used to assess fetal wellbeing. 22- Identify the placenta, fetal membranes, umbilical cord, germ layers, stages of fertilization on a given model, photograph or specimen. Teaching / Learning Strategies S. No. Topics + Objective Nos. Strategy Hours 1. Cell division (Mitosis + Meiosis) Lecture 1 2. Male reproductive system and spermatogenesis Lecture 2 Lecture 2 3. Female reproductive system, oogenesis and ovulation Female reproductive cycles Lecture 1 4. Fertilization Lecture CBS 1 2 5. Cleavage, blastocyst formation Lecture 1 6. Implantation PBL 4 7. Second week of development Lecture 1 8. Third week of development Lecture /SGS 2 /2 9. Folding of embryo Derivatives of germ layers Lecture 2 10. Placenta Lecture 1 11. Embryonic period Lecture 1 12. Multiple pregnancies PBL 4 13. Teratogenesis PBL 4 14. Calculate EDD Fetal well being Interactive Session 2 15. Identify structures on models and specimen Demonstration on Models 6 16. Embryological events from 1 to 8 week Animated videos 2 Total 36 22 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 COURSE NO: 300 COURSE NAME: COMMUNITY, HEALTH AND DEVELOPMENT The major burden of disease in developing countries is attributable to conditions that are preventable. This introductory course covers the basic concepts of community, health and development. The course demonstrates the relationship between development and health and the factors affecting community health. Objectives: By the end of the course, the student shall be able to: 1. Describe the importance of community participation in health and development 2. Facilitate patients’ self-care by enhancing their awareness level through community participation 3. Describe the interrelationship of health and development 4. Discuss the major physical, social, and biological risk factors of health and disease 5. Describe the interrelationship of factors in natural history of disease including levels of prevention 6. Discuss concept of disease prevention 7. Explain the interrelationship of modern era life style with health 8. Describe the role of Ziauddin University in Community Oriented Medical Education (COME) 23 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 Course No: 300 Course Name: Community, Health and Development Teaching / Learning strategies Obj. No. Topic 2 Interrelationship of health and development 3 Risk factors of health and diseases 4&5 1 6 Natural history of disease, level of prevention Concept of disease prevention and patient safety. Community participation in health and development Community Oriented Medical Education Strategy Hours Lecture 1 Lecture 1 Small Group Session 3 Lecture 1 Field visit and session with community representatives Assignment on field visit Lecture Total COURSE NO.: 103 COURSE NAME: GENERAL BIOCHEMISTRY OBJECTIVES: By the end of the course, the student shall be able to: 1. Describe pH, buffer, viscosity, surface tension, colloids and Donnan’s equilibrium. 2. Discuss the mechanism of dissociation of water. 3. Describe the classification and biomedical importance of carbohydrates with reference to i. Simple carbohydrates ii. Complex carbohydrates 4. Explain the structure of carbohydrates with regards to the following: i. Isomers and epimers (D and L sugars) ii. Enantiomers iii. Monosaccharides (Cyclic structure) iv. Glycosides 5. Describe the reactions of carbohydrates with regards to the following: 24 5 1 1 13 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 i. Oxidation and reduction reactions ii. Esterification 6. Explain the structure of amino acids with different types of side chain (non-polar, polar, acidic, basic, aromatic, aliphatic) 7. Describe with examples the following classes of amino acids, their properties and their biomedical importance. i. Glucogenic and ketogenic amino acids. ii. Non-protein amino acids. iii. Essential and non-essential amino acids. 8. Describe the primary, secondary, tertiary and quaternary structures of proteins. 9. Classify the proteins and describe their biomedical importance. 10. Describe coagulation, denaturation and renaturation of proteins. 11. Describe with example the following classes of lipids, their properties and their biomedical importance. i. Simple lipids ii. Compound lipids iii. Derived lipids 12. Describe the nomenclature of fatty acids: i. Saturated and unsaturated fatty acids ii. Essential and non-essential fatty acids 13. Explain physical and chemical properties of fatty acids. 14. Describe eicosanoids and their relation to health and diseases. 15. Describe the nomenclature and classification of enzymes. 16. Describe enzymes with reference to: • Active sites • Specificity • Catalytic • Cofactor efficiency • Coenzyme • Holoenzyme • Apoenzyme • Prosthetic group • Zymogens • Location 17. Explain the mechanism of enzyme action from reactants to products. 18. Discuss the effect of various factors on enzymatic activity including • Substrate • Temperature concentration • pH • Enzyme concentration 19. Discuss the effect of inhibitors on enzymatic activity which include: • Competitive inhibition • Noncompetitive inhibition • Uncompetitive inhibition 20. Explain the regulation of enzymatic activity 21. Identify different lab hazards and their solutions 25 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 22. Analyze the presence of proteins in given solutions. 23. Separate various metabolites by paper chromatography. 24. Identify different parts of HPLC and their mechanism of action. 25. Analyze the Qualitative analysis of carbohydrate. Teaching / Learning Strategies S. No. 1. Topics Strategy Hrs. Physical chemistry Lecture 2 Dissociation of water 2. Carbohydrates Lecture 3 3. Amino Acids Lecture 3 4. Protein Lecture 3 5. Lipids Lecture 3 6. Enzymes Lecture 3 7. Lab hazards Practicals 18 Qualitative analysis of proteins Chromatography HPLC Qualitative analysis of Carbohydrate Total COURSE NO.: 222 COURSE NAME: PRINCIPLES OF PHARMACOLOGY Objective: By the end of the course, the student shall be able to: 1. 2. 3. 4. 5. 6. 7. Describe various drug dosage forms and pharmacological doses. Describe various routes of drug administration and their advantages/ disadvantages. Describe the factors modifying drug absorption. Describe the major mechanisms responsible for drug metabolism(Biotransformation). Explain the factors modifying drug metabolism. Describe the basic principles of drug elimination. Describe the factors modifying drug elimination. 26 35 Ziauddin University 8. 9. 10. 11. 12. MBBS 1st Year 2015– 2016 Semester 1 Describe the principles of various pharmacokinetics parameters. Explain various mechanisms by which drugs exert their effects. Describe the different types of pharmacological graphs. a. Identify the therapeutic index and therapeutic window on a given dose response curve. b. Identify the competitive and noncompetitive antagonists on a given dose response curve. Describe the various types of adverse drug reactions. Describe the principles of drug prescription in pregnant, pediatric and geriatric patients. Teaching / Learning Strategies: S.No Objectives 1 Introduction to general pharmacology 2 Routes of drug administration and dosage form 3 4 5 6 7 8 9 10 11 12 13 14 Absorption of drug I Absorption of drug II Drug metabolism I Drug metabolism II Principles of drug excretion The principles of pharmacokinetics measures Mechanism of action of drugs I Mechanism of action of drugs II Adverse drug reactions Pharmacology in geriatric, pediatric and pregnant patients Plot dose response curve ( graded and quantal) Competitive & non competitive antagonism 27 Strategy lecture Lecture / Practical lecture lecture lecture lecture lecture lecture lecture lecture lecture lecture Practical Practical Total Hours 1 1+3 1 1 1 1 1 1 1 1 1 1 3 3 21 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 COURSE:224 COURSE NAME: INTRODUCTION TO THE PRINCIPLES OF PATHOLOGY Objectives: By the end of the course, the student shall be able to: Cellular Adaptation & Cell Injury: 1. Describe briefly different terms used in Pathology. 2. Enlist cellular adaptations 3. Describe briefly cellular responses to stress and injurious stimuli. Inflammation and Tissue Repair: 1. Describe briefly different terms used in inflammation and tissue repair. 2. Enumerate the cells involved in inflammation and their functions. 3. Describe briefly the sequence of events in acute inflammation. 4. Differentiate between acute and chronic inflammation. 5. Compare labile, stable and permanent cells in terms of their capacity for regeneration. 6. Differentiate between regeneration and repair. Hemodynamic Disorders: 1. Describe briefly following terms: • Edema • Congestion & hyperemia • Hemorrhage • Thrombosis • Embolism & infarction • Shock Neoplasia: 1. Define dysplasia, anaplasia, neoplasia, tumor, cancer / carcinoma, hamartoma, choristoma, teratoma. 2. Enlist the characteristics of benign & malignant tumors. 3. Outline the classification & nomenclature of benign & malignant neoplasms. 4. List pathways of tumor spread. 5. Compare grading & staging of neoplasms. 6. List common signs & symptoms of malignancy. Immunology: 1. Define immunity, antigen, antibody, MHC class I & II proteins, autoimmunity, immunodeficiency, hypersensitivity. 2. Discuss briefly types of immune response with examples. 28 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 3. Enlist common autoimmune, hypersensitivity & immunodeficiency disorders. Infectious Diseases: 1. Define pathogen, virulence factors, infection, incubation period, opportunistic infections, nosocomial infections, ID-50, LD-50. 2. Discuss briefly mechanisms of: • Bacterial-induced tissue injury • Viral - induced tissue injury • Fungal - induced tissue injury • Parasite - induced tissue injury 3. Enlist & comment on common microbial infections present globally and locally: • Malaria • Dengue fever • Poliomyelitis • Hepatitis A, B & C • AIDS • Worm infestations (Ascaris & Enterobius) • Typhoid/diarrhea • Tuberculosis • Influenza • Ebola virus infection 29 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 Learning Strategies Course Name: Introduction to Pathology S. Topics no Strategy Hrs 1. Introduction to Pathology & Cell Injury lecture 1 2. Cellular response to injury lecture 1 lecture 1 Inflammation & repair – terms used 3. Types of inflammatory cells sequence of events in inflammation 4. Edema, congestion, hyperemia, hemorrhage lecture 1 5. Thrombosis, embolism & infarction, shock lecture 1 lecture 1 lecture 1 Define terms used in neoplasia 6. Characteristics & nomenclature of tumors Tumor spread 7. Grading & staging Common signs & symptoms of malignancy 8. Define terms used in immunology lecture 1 9. Types of immune responses with examples lecture 1 lecture 1 10. Define terms used in infectious diseases Common infection in Pakistan 11. Mechanisms of bacterial & viral infections with examples lecture 1 12. Mechanisms of fungal & parasitic infections with examples lecture 1 Total 30 12 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 COURSE NO. 202 COURSE NAME: CELL BIOLOGY This course covers cell structure, ultra-structure, and its functions including ionic and electrical potential gradients, transport across the cell membrane, excitability and action potentials, neuromuscular transmission, muscle energetic and contractility, metabolic interrelationships and multiplication as they occur in the individual. It also covers the responses of cells to injury. Objectives By the end of the course, the student shall be able to: 1. Explain the organization of cells to tissue, tissues to organ and organs to system. 2. Describe the structural organization of cell membrane and discuss the function of its components. 3. Explain the cell membrane function with reference to i) Resting membrane potential ii) Action potential 4. Describe the modes of transport across cell membrane. i. Passive Transport ii. Active Transport iii. Facilitated diffusion iv. Osmosis v. Endocytosis vi. Phagocytosis vii. Pinocytosis viii. Receptor mediated endocytosis ix. Exocytosis 5. Describe the structure and functions of the following cytoplasmic organelles: i. Golgi apparatus ii. Lysosomes iii. Peroxisomes iv. Smooth endoplasmic reticulum v. Rough endoplasmic reticulum vi. Ribosomes vii. Cellular inclusions viii. Mitochondria 6. Describe the ultrastructure and function of the cytoskeleton 7. Describe the structure and functions of nucleus. 31 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 8. Describe cell to cell adhesion. 9. Describe the structure, synthesis, degradation and functions of the components of extra-cellular matrix with reference to the following: i) Glycosaminoglycans and proteoglycans ii) Collagen iii) Elastin 10. Describe the parts of microscope. 11. Discuss the basic tissues of the body and identify under microscope. i. Epithelium ii. Muscle tissue iii. Connective tissue iv. Neural tissue 12. Describe cell to cell communications. 13. Discuss the synthesis and degradation of purines, pyrimidines, nucleotides and nucleic acids. 14. Discuss DNA replication, repair and proof reading in prokaryotic and eukaryotic cells. 15. Describe transcription and post transcriptional modifications. 16. Discuss synthesis of proteins. 17. Describe the regulation of cell cycle and cell division. 18. Describe the pathogenesis and clinical significance of the following growth disorders and cellular adaptations to injury: i. Atrophy, ii. Hypertrophy, iii. Hyperplasia iv. Metaplasia v. Dysplasia 19. Describe the agents of cell injury. 20. Discuss the response of cell to injury with particular reference to. i. Hypoxic injury. ii. Ischemic reperfusion injury. iii. Free radical injury. iv. Injuries through Microorganism v. Chemical injury vi. Radiation injury. 21. Describe causes mechanisms and significance of apoptosis. 22. Discuss the pathogenesis and types of necrosis. 23. Describe the etiology, pathogenesis and morphology of intracellular accumulations (lipid, proteins, glycogen and pigments). 24. Describe the pathogenesis and clinical significance of pathologic calcifications (dystrophic and metastatic calcification). 32 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 25. Discuss Carcinogenesis and various environmental factors leading to it. 26. Discuss the differences between the benign and malignant tumors and spread of tumor. 27. Classify various anti-cancer drugs. 28. Describe the mechanism of resistance to anti-cancer therapy. 29. Describe the mechanism of action, indications and side effects of : a) Cell-cycle specific drugs b) Cell-cycle non specific drugs 33 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 Course Name: Cell Biology Teaching / Learning Strategies S. # Topic Introduction to Cell Biology (organization of cells, tissues and organ systems) Strategy Hrs. Lecture 1 2. Introduction to microscopy Practical 2 3. General histology 1. 1 a Epithelium Lecture 1+1 b Muscle tissue Lecture 1 c Connective tissue proper Lecture 1+1+1 d Bone Lecture 1 e Cartilage Lecture 1 f. Neural tissue Lecture 1 CBS 2 CBS 2 5. Structure and functions of cell membrane (RMP & AP) Transport across the cell membrane 6. Cell Organelles Lecture 2 7. Cytoskeleton CBS 2 8. Extracellular matrix Lecture 2 9. Cell to cell adhesion Lecture 1 10. Intracellular signaling Lecture (2) 1+1 11. Structure and function of nucleus Lecture 1 12. Purine & pyrimidine metabolism Lecture/PBL 2/4 13. DNA and RNA Lecture 2 14. DNA replication Lecture 1 15. DNA repair Lecture 1 16. Transcription Lecture 1 17. Translation Lecture 1 18. Cell cycle and its regulation Lecture 1 Lecture 1 4. 19. Cellular adaptation 20. Disorders of cell growth 34 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 21. Causes of Cell injury Lecture 1 23. Reversible and irreversible cell injury PBL 4 24. Necrosis PBL / Lecture 4/1 25. Apoptosis Lecture 1 26. Intracellular accumulation Lecture 1 27. Metastatic calcification Lecture 1 28. Benign and Malignant tumor Lecture 2 29. Mechanism of tumors spread Lecture 1 30. Physical, Chemical and viral carcinogen Lecture 1 31. Carcinogenesis PBL/ Lecture 4+2 Lecture 1 33. Anticancer Drugs Classification and mechanism of resistance of 34. Anticancer Agents Cell cycle specific and non specific 35. anticancer drugs PBL 4 Lecture 2 Lectures 2 36. Histology practical Practical 22. Mechanism of cell injury 32. Carcinogenesis with reference to growth regulating genes a Epithelium 2+2 b Muscle tissue 2 c Connective tissue proper 2+2 d Bone 2 e Cartilage 2 37. Action Potential Lecture 1 38. Cell injury Practical + Kodachrom e/ Morphology 4+1 Total 93 39. Neoplasia CBS = Case Based Session PBL = Problem Based Learning 35 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 COURSE NO. 203 COURSE NAME: GENETICS Objective: By the end of the course, the student shall be able to: 1. Interpret the genetic basis of the following diseases and counsel the family. A) Single gene defects: i. X-linked recessive Examples: Hemophilia A, Duchenne muscular dystrophy and Beta Thalassemia ii. X-linked dominant Examples: X-linked hypophosphatemic rickets. iii. Autosomal recessive Examples: Cystic fibrosis, sickle-cell disease, Xeroderma Pigmentosum, SCID, Emphysema (Alpha 1 antitrypsin Deficiency) and Hemochromatosis iv. Autosomal dominant Example: Huntington’s disease and Marfan Syndrome v. Mitochondrial disorder Example: Leber’s Hereditary Optic Neuropathy vi. Atypical Inheritance Examples: Fragile X Syndrome B) Chromosomal Abnormalities: Examples: Turner syndrome, Downs Syndrome, Klinefelter’s Syndrome and Angelman/Prader-Willi Syndrome C) Multifactorial Abnormalities: Examples: Hereditary non-Polyposis Colonic Carcinoma and Diabetes Mellitus. 2. Interpret the following investigation reports. • Non Invasive: o Ultrasonography • Invasive: o Maternal Serum Testing (Alpha Fetoprotein, Beta HCG, Triple Test) o Chorionic Villous Sampling o Amniotic Fluid Analysis 3. Observe the following genetic techniques a) Extraction of DNA b) PCR c) Electrophoresis 36 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 Interpret the results of the following techniques a) Karyotyping b) FISH c) Blotting Techniques 5. Describe personalized medicine. 6. Describe clinical aspects of genetics 4. 37 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 Teaching / Learning Strategies TOPIC Numbers Hrs. PBL 6 24 Lectures 6 6 2 Presentation 4 8 1 Post PBL Sessions 3 6 3 Practical/Demonstration 3 9 5 Personalized medicine 1 1 6 Lectures 3 3 1 1A(v), 2,3, 4 Strategy Total 57 PBL = Problem Based Learning 38 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 COURSE NO: 301 COURSE NAME: BASIC BIOSTATISTICS Biostatistics is the application of statistics to medical problems in order to appreciate the analysis of and variation is data. This course includes data presentation, measures of central tendency & dispersion, normal distribution and rules of probability. The students work on actual data sets to apply the concepts learnt in the module. Objectives: By the end of the course, the student shall be able to: 1. Classify the types of variables in a given data set: a. Qualitative: nominal/ordinal b. Quantitative: discrete/continuous 2. Present data in form of tables and graphs: • Frequency table • Histogram • Frequency polygon • Cumulative frequency polygon • Stem and leaf • Bar chart • Pie chart • Box and Whisker plot 3. Interpret data from tables and graphs: • Same as objective # 2 4. Determine the likelihood of occurrence of a given event using the rules of probability: a. Multiplication rule b. Additional rule c. Counting rule 5. Summarize data using the appropriate measures of central tendency and variation: a. Central tendency: Mean, Median & Mode b. Variation: Range, standard deviation & Coefficient of variation 6. Explain the properties of normal distribution. 7. Determine the area under the normal curve for a given data set using z – table. 39 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 COURSE NO: 301 COURSE NAME: BASIC BIOSTATISTICS Teaching / Learning strategies Obj. No. 1 2&3 Topic Classify the types of variables in a given data set Present data in form of tables and graphs Interpret data from tables and graphs 4 Determine the likelihood of occurrence of a given event using the rules of probability 5 Summarize data using the appropriate measures of central tendency and variation 6&7 Explain the properties of normal distribution Determine the area under the normal curve for a given data set using z – table 40 Strategy Hours Lecture 1 Lectures 2 Small Group Session 3 Lectures 2 Small Group Session 3 Lectures 2 Small Group Session 3 Lecture 1 Small Group Session 3 Total 20 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 COURSE NO: 218 COURSE: CARDIOVASCULAR SYSTEM Objectives: By the end of the course, the student shall be able to: 1. Describe the gross structure of the heart with its blood supply, venous drainage and nerve supply 2. Describe the great vessels with their branches. 3. Describe the parts and arrangement of pericardium. 4. Describe mediastinum and its contents. 5. Describe the structure of thoracic cage and its components. 6. Identify different chambers, valves, and coverings of the heart and great vessels on a specimen, model, dissected body and diagrams. 7. Describe the microscopic structure of heart and blood vessels 8. Describe the development of cardiovascular system with particular reference to following congenital heart defects or anomalies: a. Ventricular septal defect b. Atrial septal defect c. Tetralogy of Fallot d. Coarctation of aorta e. Transposition of great vessels f. Patent ductus arteriosus 9. Discuss the effects of above congenital heart defects or anomalies on circulatory system. 10. Describe fetal circulation and changes that occur at birth. 11. Explain the cardiac muscle fibers with special reference to the following: a. Structure b. Properties c. Contraction coupling d. Ionic basis of different phases of action potential e. Impulse generation and conduction system of heart f. Changes in serum sodium, potassium, calcium and, epinephrine, atropine, acetylcholine and dopamine levels on the excitation. 12. Describe the effects of ANS drugs on CVS 13. Interpret the pressure and volume changes in different phases of cardiac cycle. 14. Describe the principles of normal ECG and changes associated with clinical conditions 15. Interpret the following in the given ECGs -Sinus tachycardia -S.A. nodal and A.V. nodal block 41 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 -Sinus bradycardia -Bundle branch blocks -Premature atrial contraction -Ventricular hypertrophy -Premature ventricular contraction -Myocardial infarction -Atrial flutter -Atrial fibrillation -Ventricular tachycardia -Ventricular fibrillation 16. Describe autonomic control of CVS. 17. Investigate the following cases on the basis of etiology, pathogenesis, risk factors and preventive measures: a. Atherosclerosis b. Hypertension c. Aneurysm d. Vasculitis e. Tumors of blood vessels f. Heart failure g. Ischemic heart disease i. Angina ii. Myocardial infarction h. Valvular heart disease i. Cardiomyopathy j. Pericarditis k. Deep vein thrombosis l. Shock 18. Interpret the biochemical markers associated with myocardial infarction 19. Describe the following drugs on the basis of their mechanism of action, their pharmacodynamics, pharmacokinetics, indications, side effects and contraindications of. a. Antianginal b. Anti hypertensive c. Drugs for Myocardial infarction d. Drugs for Shock e. Drugs used for CCF 20. Interpret the production of normal and abnormal heart sounds (types of murmurs) on phonocardiogram tracing in the following conditions and relate them to gross timing in the cardiac cycle. - Mitral stenosis -Mitral regurgitation - Aortic stenosis -Aortic regurgitation - Pulmonary stenosis -Pulmonary regurgitation - Tricuspid stenosis -Tricuspid regurgitation - Ventricular septal defect 21. Interpret the effects of the following in the given ECG. 42 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 a. Exercise b. Ions (Na, K, Ca) 22. Discuss the law of physics in circulatory hemodynamics 23. Interpret the effects of various drugs (atropine, epinephrine, norepinephrine, acetylcholine, isoprenaline and propranolol) on heart rate and blood pressure using computer simulated software. 24. Explain the mechanism of epinephrine reversal on the basis of given graph 25. Describe cardiac output, stroke volume output, ejection fraction and blood pressure. 26. Calculate ejection fraction, end systolic volume, end diastolic volume, stroke volume output and cardiac output from a given set of data. 27. Discuss the nervous and humoral regulation of cardiac output stroke volume output and blood Pressure at rest and during exercise. 28. Discuss the mechanism (s) involved in the production of circus movement. 29. Classify anti arrhythmic drugs on basis of mechanism of action, indication and adverse effects. 30. Discuss the drugs acting on Renin Angiotensin system according to mechanism of action, indication and adverse effects 31. Describe the path physiology of edema with special emphasis on CCF along with the mode of action & adverse effects of drugs used in CCF 32. Describe the regulation of coronary, cerebral, splanchnic, pulmonary, and cutaneous circulation. 33. Describe source and functions of lymph and mechanism of lymph flow. 34. Describe digestion and absorption of: a) fats b) fat soluble vitamin 35. Describe the risk factors, preventive measures, pharmacokinetics and pharmacodynamics of drugs used in hyperlipidemia. 36. Discuss the mechanism of action, pharmacokinetics, pharmacodynamics, indication and adverse effects of antihyperlipidemic drugs. 37. Explain cholesterol metabolism and its derivatives. 38. Explain metabolism of a. Chylomicron b. HDL 43 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 c. LDL d. VLDL 39. Identify the cardiovascular structure in radiograph. 40. Surface marking of heart and great vessels Skills 1. Record and interpret ECG of a normal subject. 2. Perform examination of the cardiovascular system which includes: • Physical examination of CVS • Examine the radial, brachial, carotid, femoral, popliteal, dorsalis pedis and posterior tibial pulses. • Recording of blood pressure manually in different positions. • Interpret the action of various drugs on intact/isolated heart & BP using computer simulation software. • Interpret the following in given clinical scenarios. a. Cholesterol b. Triglycerides c. HDL and LDL • Perform CPR on a mannequin. • Communicate risk to all patient regarding medication use and drug interactions with reference to cardiovascular diseases Course No: 218 Course: Cardiovascular System Learning Strategies S No Topic 1. Introduction to the course 2. Gross structure of the heart Hrs. 1 Topics Demonstration/Models a. Thoracic cage 1/2 b. Mediastinum 1/2 c. Pericardium & Pericardial sinuses ( nerve supply, functions and clinical relevance) Heart – anatomical position, borders and surfaces Right and left atrium 1/2 d. 44 1/2 17 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 e. Right and left ventricle 1/2 f. 1/2 5. Valves of the heart, auscultatory areas & anatomical basis of cardiac murmurs Arterial supply, venous drainage and nerve supply of heart. Anatomical basis of Angina, MI, CABG and PTCA Venous drainage and nerve supply of heart Aorta and its branches. Venous drainage and nerve supply of heart. Pulmonary trunk, superior and inferior vena cava Surface marking of heart and great vessels Microscopic structure of heart and vessels Development of heart I 6. g. h. i. j. 4. 1/2 1/2 1/2 1/2 Lecture Practical 2 6 Lecture 1 Development of heart II Lecture 1 7. Development of heart III Lecture 1 8. Development of Arterial and Venous system Etiology, pathogenesis and clinical course and complications of deep venous thrombosis. Lecture 1 Lecture 1 PBL/ Lecture 1 4 1 Lecture 1 PBL 4 Lecture 1 9. 10. 12. Etiology, , risk factors, preventive measures, pathogenesis, pharmacodynamics, pharmacokinetics and treatment of ischaemic heart disease Anti-anginal drugs on the basis of mechanism of action. Hemodynamic and side effects and common drug-drug interaction of antianginal drugs. Congenital heart defects 13. Common types of congenital heart 11. 45 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 diseases 14. 15. Fetal circulation and circulatory changes at birth Autonomic control of CVS. 16. Electrical events in cardiac tissue 17. Peripheral pulses 18. Cardiac muscle fiber and excitation contraction coupling in cardiac muscles Effects of ions & hormones on cardiac muscle Conducting system of heart 19. 20. 21. 22. 23. 24. 25. 26. Lecture 1 Lecture 1 Lecture 2 Practical 2 Lecture 1 Lecture 2 Interactive Session 1 Lecture 2 PBL Lecture 4+1 Etiology, pathogenesis, clinical course, complications and diagnosis of infective endocarditis. Lecture 1 Etiology, pathogenesis, clinical course, complications and diagnosis of atherosclerosis. Lecture 1 Etiology, pathogenesis, clinical features and complications of pericarditis. Lecture 1 Lecture 2 Practical + Lecture 2+1 Lecture 1 Lecture 2 Lecture 1 Organ effect (CVS)of drug acting on ANS Etiology, pathogenesis, clinical course and diagnosis of rheumatic fever and rheumatic heart disease. 27. Pressure volume changes during cardiac cycle. Principles of ECG 28. Vectorial analysis of ECG 29. Arrhythmias on ECG and other ECG changes. Classification of anti arrhythmic agents 30. 46 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 31. Murmurs/ ECG / Cardiac cycle Lecture 1 32. Hemodynamics Lecture 2 33. Cardiac output & its regulation Lecture 2 34. Blood pressure & its regulation Lecture 2 35. Blood Pressure recording Practical 2 36. Etiology pathogenesis effect of hypertension on blood vessels and heart. Mechanism of action, adverse effects, and drug interactions of antihypertensive drugs. Specialized circulation Lecture 1 PBL/ lecture 4/2 Lecture 2 Lecture 2 Lecture 1 Lecture 1 Lecture PBL 2 4 Lecture PBL 1 4 CBS 1 Morphology Practical 2 Lecture 1 Lecture 1 Lecture 2 37. 38. 39. 40. 41. 42. Capillary circulation, fluid exchange & edema formation Pathophysiology of edema. Neurohormonal control of circulation Cardiac failure & drugs used in CCF 43. Pathogenesis of different types of shock with their causes 44. Mechanism of action and adverse effects of drugs used in the treatment of various types of shock. 45. CVS Digestion and absorption of fats and fat soluble vitamins 46. 47. 48. Cholesterol metabolism and its derivatives Metabolism of Chylomicron,HDL,LDL and VLDL 47 Ziauddin University 49. 50. 51. 52. 53. 54. 55. 56. 57. 58. 59. 60. MBBS 1st Year 2015– 2016 Semester 1 Interpret the biochemical markers associated with myocardial infarction Antihyperlipidemic drugs according to their mode of action and their clinical uses, common drug-drug interactions and adverse-effects. Epidemiology and prevention of cardiovascular diseases CVS radiology Examination of the Cardiovascular System Surface anatomy of heart and great vessels Interpret the following in given clinical scenarios Cholesterol ,Triglycerides ,HDL and LDL Interpret the graph of epinephrine reversal. Interpret the actions of various drugs on blood pressure & intact / isolated heart using computer simulation software. Perform CPR Interpret the following in the given ECGs Sinus tachycardia, SA nodal, AV nodal block, Sinus bradycardia, Bundle branch blocks, Premature atrial contraction, Ventricular hypertrophy, Premature ventricular contraction, Myocardial infarction, Atrial flutter, Atrial fibrillation, Ventricular tachycardia, Ventricular fibrillation Pathology Practical / morphology. 48 Lecture 1 CBS 2 Lecture 1+1 Lecture 2 Practical 4 Practical 2 Practical 2 Practical 2 Practical 2 Skill 3 Practical 4 Practical 6 Total 143 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 Learning Resources Recommended Books Anatomy • • • • • • K.L. Moore. Clinically Oriented Anatomy, 6th edition 2009. B Young, J.W. Heath. Wheater’s Functional Histology, 5th edition 2006. Keith L. Moore. The Developing Human 9th edition 2011. Medical Histology by Laiq Hussain 4th ediation 1999. Richard S. Snell. Clinical Anatomy for Medical Students, 9th edition 2011. Langman’s Medical Embryology 12th edition 2011. Physiology • • • • • • • Arthur C. Guyton, John E. Hall. Textbook of Medical Physiology, 12th edition 2010. Recommended Robert M. Berne, Matthew N. Levy. Principle of Physiology, 5th edition 2006. William F. Ganong. Review of Medical Physiology,24th edition 2012. Sherwood, Lauralee. Human physiology : from cells to systems 8th edition 2012. Bijlani, R.L. Understanding Medical physiology : a textbook of medical students 4th edition 2012. Biochemistry • Robber K. Murray, Daryl K. Granner, Peter A. Mayes, Victor W. Rodwell. Harper’s Biochemistry, 29th edition 2012. • Pamela C. Champe, Richard A. Harvey. Lippincott’s Illustrated Review of Biochemistry, 5th edition 2010. • Harold C. Sox Jr. Common Diagnostic Tests, use and interpretation 2nd edition 1990. • Jhon F. Zilva, Peter R. Pannall, Philip D. Mayne. Clinical Chemistry in Diagnosis and Treatment, 5th edition 1988. • U. Satyanarayana. Biochemistry 2006. Community Health Sciences • Mohd. Ilyas et. Al. Community Medicine and Public Health, 7th edition 2006. • Kumza JW, Bohnenblust SE, Basic Statistics for the Health Sciences, 5th Edition 2005. 49 Ziauddin University • MBBS 1st Year 2015– 2016 Semester 1 CHS Course Book (available from CHS / ZU). Pharmalcology • Bertram G. Katzung. Basic and Clinical Pharmacology, 12th Edition. 2011. • Bennett and Brown. Clinical Pharmacology, 11th Edition. 2012. • Goodman and Gillman. The Pharmacological Basis of Therapeutics, 12th Edition. 2011. • Rang, Dale, Ritter and Moore. Pharmacology, 7th Edition. 2012. • Tripathi. Essentials of Medical Pharmacology. 6th Edition. 2008. Pathology • Peter D. Turnpenny, Emery’s Elements of Medical Genetics (14th ed.). New York: Churchill Livingstone. 2011. • Cotran RS, Kumar V and Collins T. Robbin’s Pathologic Basis of Disease (8th ed.). Philadelphia: W.B. Saunders. 2012. • Walter JB and Talbot IC. Walter and Israel’s General Pathology (7th ed.). New York: Churchill Livingstone. 1996. • Kumar V, Cotran RS, and Robbins SL. Basic Pathology (9th ed.). Philadelphia: W.B. Saunders. 2012. • Rubin E, Pathology (6th ed.) Philadelphia: Lippincott-Raven. 2011 • Ivan Roitt. Riott’s Essential Immunology (12th ed.). New Delhi:I.K. International Pvt. Ltd. 2011. • Wheater P et al. Basic Histopathology: A Color Atlas and Text (4th ed.). Edinburgh: Churchill Livingstone. 2002. Computer Assisted Learning: Topic - Catalogue # Interactive Atlas of Human Anatomy Explorations in Cell Biology and Genetics Interactive Physiology Wheater’s Interactive Histology Radiological Anatomy Imaging Atlas of Human Anatomy 2.0 Human Anatomy Virtual Human Atlas Comprehensive Microscopic Anatomy 50 43 and 116 44 and 115 48 52 54 67 76 78 77 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 Video: Statistics. Decisions through Data. 51 12-16 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 STUDENT CODE OF CONDUCT 1. 1.1 1.2 1.3 2. 2.1 INTRODUCTION: The ZU was established with the objective of developing human resources appropriately equipped to deal with the problems, which are of particular relevance to its environment. The University considers its students to be mature and responsible individuals and makes all efforts for developing matching professional attributes. The University expects that behaviour of the students, within and outside the premises of the University, should be in conformity with the highest standards of honesty, morality and discipline. The students should respect the rights and privileges of the members of the University community at all times. They should refrain from conduct that might damage the reputation of the University or any of its programmes. The students should refrain from any conduct that may lead to the disruption of an academic programme of the University and from cheating and plagiarism in any setting of the University. THE CONDUCT OF STUDENTS: GENERAL CONDUCT: All students should present themselves with dignity befitting their status as mature professionals and responsible citizens. a. Students in all settings on campus are expected to dress in a simple and decent manner. b. Students individually or as a group, should obtain written ZU approval before organizing or assisting in organizing demonstrations, rallies or picketing on campus. c. Students individually or as a group should refrain from disseminating or causing to disseminate material or engage in activity which hinder or prevent the full participation of another person or group in the life of the University. d. Religious and social activities held on campus must have prior written University authorization. e. Students should ensure that their actions do not endanger or threaten the health, safety or well being of other persons. f. Students should refrain from any behaviour, which can be interpreted by others as sexual harassment. g. Students should obtain written authorization before making public statements, communication, or correspondence with the press or other media for mass communication on behalf of the University. 52 Ziauddin University h. I. 2.2 MBBS 1st Year 2015– 2016 Semester 1 Unless otherwise authorized in writing the students should refrain from inviting government and or foreign dignitaries, ministers, representatives of foreign governments/agencies or other public personalities in their official capacity on campus. Students should refrain from any activity, which is subversive of discipline and may constitute misconduct. ACADEMIC CONDUCT: All students should diligently apply themselves to their registered courses of study. They should respect the confidentiality of information and should use it in no other circumstances than for professional and authorized academic purposes. a. Students should attend lectures, PBLs, tutorials, seminars, practicals, clinics and ward assignments, examinations and other scheduled courses, activities and assignments given by the faculty except for reasons acceptable to the University. b. Students should ensure that any original academic writing, including essays, theses, research projects or assignments in a course or programme of study either represents their own words, ideas, images or data or is appropriately referenced. c. Students should obtain authorization before procuring, possessing, distributing or receiving any confidential material pertaining to academic tests, examinations, research or laboratory results from any source. d. Students should respect the confidentiality of information pertaining to patients, including their records or files. RULES: 1. INTRODUCTION: 1.1 Students of ZU are required to exhibit good attitude and discipline. Guidelines have been delineated in the University’s Code of Conduct (“Code of Conduct”) framed by the University to provide students with a reference to the standards for discipline. It is expected that all students will strictly uphold and adhere to the Code of Conduct, but in cases where there are grounds to suspect a breach or any infringement of the Code of Conduct or disregard or contempt of the Code of Conduct, disciplinary action may be initiated for such behaviour committed either within or outside the precincts of the University or any establishment, project or setting thereof anywhere located. The reference to the expression 53 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 “University” shall mean and include (unless the context provides otherwise), any establishment, project or setting of the University located anywhere in the world. 1.2 The disciplinary procedure to be followed upon breach and /or infringement of the Code of Conduct is defined herein, along with the actions, which constitute disciplinary offences and the decisionmaking authority. 2. DISCIPLINARY OFFENCE: Without prejudice to the generality of the provisions of the Code of Conduct and the provisions of Rules 1.1 and 1.2, the following conduct will constitute disciplinary offence: 2.1. MINOR OFFENCES: a. Repeated failure to conform to scheduled instruction, practical work, examination, clinical assignments and or forcing other students to act likewise. b. Smoking, eating and drinking are prohibited in the University Premises. NOTE: All minor offences will be dealt with as major if repeated. 2.2. a. b. c. d. e. f. g. h. i. MAJOR OFFENCES: Assault on students, members of staff, faculty or patients. Any form of unauthorized picketing, rallies, demonstrations or organized obstructions of any student/University/University Hospital function in any manner whatsoever. Any attempt to conceive, design or affect any plans of whatever nature whose object or consequence is to disrupt academic programmes of the University or its operations. Malicious acts, theft, willful damage or misuse of University property. Disorderly conduct and/or molestation of other members of the University Community within and outside the University premises. Bringing unauthorized persons in the university premises or any other building related to the University. Cheating, plagiarism and or use of unfair means in examinations or any other academic setting. Possession, use and display of firearms, drugs, alcohol or other contraband items on campus or at University related events. Any other offence, which is considered to be harmful to the academic atmosphere. 54 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 DISCIPLINARY ACTIONS: The University will have the powers to impose any one or more of the following actions. However, nothing will preclude the University from requiring any student or parent or both to execute any bond, assurance or undertaking to support expected conduct throughout his/her stay at the University. MINOR DISCIPLINARY OFFENCE will be liable to one or more of the following sanctions. a) Counselling of the student. b) Probation: A student can be put on probation for a specified period of time with mandatory periodic counseling. c) A letter of warning or reprimand to the student with information to the parents. d) The payment of fine by the offender commensurate with the nature and gravity of the offence committed amounting up to 5% of the annual fees of the student. MAJOR DISCIPLINARY OFFENCE will be liable to one or more of the following sanctions a) The payment of fine by the offender commensurate with the nature and gravity of the offence committed amounting up to 5% of the annual fees of the student. b) Suspension from the University for a specified period. c) Expulsion from the University. d) Any other penalty which the University may deem fit to impose. DISCIPLINARY PROCEDURE: The following steps constitute the disciplinary procedure. 4.1 Any disciplinary offence not of serious nature may be brought to the attention of the offender by an affected student through the faculty/staff member concerned of the University. The purpose of this in the first instance is to resolve the matter through constructive criticism ounseling and/or admonition. The expression “offence not of serious nature” appearing herein above shall be such offence as is considered as an offence of not a serious nature by the faculty/staff member of the University in his/her sole discretion. The expression “faculty/staff member of the University” shall be in relation to the following Units of the University namely, (i) Medical College, (ii) College of Nursing, (iii) College of Physical Therapy (iv) School Medical Technology (v) College of Pharmacy. (vi) College of Speech Language Therapy (vii) Dental college (viii) Faculty of Media Sciences. 55 Ziauddin University 4.2 4.3 4.4 4.5 5. 5.1 5.2 MBBS 1st Year 2015– 2016 Semester 1 If the matter is not resolved or the student repeats an offence or if the offence is a serious one, the head of the Unit concerned i.e. (i) in the case of Medical College/College of Pharmacy – the Dean, (ii) in the case of school of Medical & CSLT Technology – the Director and (iii) in the case of school of Physiotherapy / School of Nursing respective dean/Principals or their designate will be informed, who shall advise investigation by the Disciplinary Committee constituted under Rule 5.1. The outcome of the investigation shall be communicated to the head of the relevant Unit. He/she may act upon the recommendation of the Disciplinary Committee or in accordance with his/her judgment. The decision shall then be communicated to the offender. The matter shall be resolved normally within fourteen working days of the day the Head of the Unit is informed of the offence. A student may appeal in writing against such a decision to the Head of his Unit within ten working days of the decision having been communicated in writing to the student. The student shall within the said period of time submit his/her appeal to the Head of his/her Unit i.e. Dean or his designate in the case of Medical College and College of Pharmacy, Dental College, College of Nursing– (ii) in the case of Institute of Medical Technology the Director and (iii) in the case of College of Physical Therapy Principal as the case may be for onward submission to the Vice Chancellor. The Head of the Unit shall request the Vice chancellor to constitute the Appeal Committee under Rule 5.2 and refer the matter to it for consideration of the appeal. The Appeal Committee shall take up and review the case and communicate its decision in writing to the VC normally within ten working days. The VC may act upon the recommendations of the Appeal Committee or in accordance with his/her own judgment. If the decision is not acceptable to the student, he/she may request a final review by the VC. The VC’s decision thereafter shall be final and binding. STRUCTURE OF THE DISCIPLINARY AND APPEAL COMMITTEES: The structure of Disciplinary Committee shall consist of five members of the faculty, one of whom shall be the Chairperson. The Chairperson and members may serve for three years. They may be appointed for another term of two years. The Committee shall be appointed by the ZU Academic Council. A University Appellate Committee shall be appointed as and when required, by the VC. It shall consist of three faculty members (one of whom shall be the chairperson) who have not been associated with 56 Ziauddin University 5.3 MBBS 1st Year 2015– 2016 Semester 1 ounseling or with investigation of the student’s current or his/her any previous offence. The Disciplinary Committee and the Appellate Committee will have authority to call for evidence or questioning any person witness to the offence/ event reported for investigation to the disciplinary committee. 6. DISCIPLINARY AUTHORITY: Notwithstanding anything contained herein, the VC shall be the final disciplinary authority of the University with powers to: Appoint or change a Disciplinary Committee and define disciplinary procedures. a. Suspend the privileges of enrolment of a student who is suspected of a breach of the code, pending investigation. b. Act upon the recommendations of the Disciplinary Committee which may include expulsion of a student from the University. c. Appoint an Appeal Committee and define procedures for appeal. d. Take any measure that may be necessary for ensuring effective disciplinary procedures. e. Delegate any of his authority. f. Make, alter and modify the Disciplinary Procedure (Rules). DEFINITIONS: The said expression shall mean and include any person enrolled with the University for a course of studies leading to an undergraduate or postgraduate degree or diploma or certificate within the University or the University Hospital or any person registered with any other University or Institution who has been accepted for an approved programme of study or training at ZU. Vice Chancellor: The VC shall be deemed to mean the VC of the University unless otherwise stated. Dean: Unless otherwise indicated, the “Dean” shall be interpreted as the Dean of (a) Medical College. (b) Post Graduate Studies. (Clinical / Basic) (c) Pharmacy. (d) College of Nursing 57 Ziauddin University MBBS 1st Year 2015– 2016 Semester 1 Unit: Unless otherwise indicated, a unit shall mean the Medical College, College of Physical Therapy, College of Pharmacy or any Institute, College or School of the University. Head of the Unit: Shall mean Director of the Medical Technology & College of SLT, Principle of College of Physiotherapy and Dental College, Dean or his/her designate for the Medical College, Pharmacy. Suspension: Suspension requires a student to withdraw completely from all the activities of the University for a specified period of time. Upon expiry of the period of suspension the student will be re-admitted, contingent upon the terms and conditions of the suspension without any obligation or liability whatsoever on the part of the University or any of its staff/faculty members or officers. Expulsion: Expulsion means termination of enrolment in the University. Interns and Residents: These shall be deemed to be the students of the University. Fine: This is an order to student for payment of a sum of money to the University as penalty for any offence committed by the student. The student may or may not be permitted to continue with the course of studies until the fine has been paid. ⇒⇒⇒⇒ END ⇐⇐⇐⇐ 58 3 7-12 4 14-12 5 21-12 6 28-12 7 4-1 1 11-1 2 18-1 3 25-1 4 1-2 7 8-2 6 15-2 7 22-2 8 29-2 1 7-3 1 14-3 1 21-3 2 28-3 3 4-4 4 11-4 5 18-4 6 25-4 1 2-5 1 9-5 1 16-5 Semester Break 2 30-11 Semester 1 Exam Written-SPE & VIVA 1 23-11 Self Study ZIAUDDIN MEDICAL COLLEGE Batch-XXI (1st Year MBBS) Semester-I (November 2015 to May 2016) Week Introduction to Medical Studies Introduction to Human Body & Anatomical Terms Cell Biology & Genetics General Embryology Introduction to Community Health & Development Introduction to Biochemistry General Principles Of Pharmacology General Pathology CAT-1 Written Basic Biostatistics Co- Curricular Activity Use of Library Study Skills CAT-3 Written + SPE CAT-2 Written 1 30-5 2 6-6 3 13-6 4 20-6 5 27-6 6 4-7 1 11-7 Respiratory System CHS Exam CAT-Continuous Assessment Test SPE- Structured Practical Examination 2 18-7 3 25-7 4 1-8 5 8-8 6 15-8 Hemopoietic & Immune System CAT-1 Written + SPE CAT-2 Written SPE 7 22-8 1 29-8 1 5-9 Semester II Exam Inferential Biostatistics 1 23-5 Self Study Semester-II (May 2016 - September 2016) Week Cardiovascular System CHS Exam CAT-4 Written -SPE
Similar documents
ZIAUDDIN MEDICAL UNIVERSITY
Consists of following for each module and generic courses Course No Duration of Semester and Modules Objectives of each module Learning Strategies Number of Hours
More information