Sodium Stearyl Fumarate 3-22-16

Sodium Stearyl Fumarate
CAS# 4070-80-8
O
O
O-
Na+
O
Synonyms: Sodium Stearyl Fumarate; Sodium Octadecyl Fumarate;
trans 2-Butenedioic acid mono octadecyl ester sodium salt; Sodium Stearylfumarate
Molecular Formula: C22H39NaO4
Specifications: White Powder. Meets USP Specifications
Sodium Stearyl Fumarate (CAS# 4070-80-8) Applications:
 Water Soluble lubricant used in pharmaceutical tableting (tablet compression)
manufacturing process
 Sodium Stearyl Fumarate is increasingly becoming the lubricant of choice compared to the traditional
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use of magnesium stearate for tablet compression lubricant applications
Literature Studies indicate that sodium stearyl fumarate may offer an enhanced disintegration and
dissolution rate in tableting operations as compared to magnesium stearate
Pressure Chemical (PCC) can Contract Manufacture
your Sodium Stearyl Fumarate Needs
O
Na
O
O
O
Scanning Eletron Microscopy (1000x)
Sodium Stearyl Fumarate
Use as a lubricant in the tableting industry
Relevant Literature:
Kruse, S., S. Gebert, K. Meyer-Böhm, A. Maschke, and K. Kolter. "Compression Characterization and Lubricant
Sensitivity of Orally Disintegrating Tablets Based on Ludiflash®."
Shipar, Md Abul Haider, A. Wadhwa, and C. Varughese. "AFFECT OF GRANULE SIZES, TYPES AND CONCENTRATIONS
OF LUBRICANTS AND COMPRESSION FORCES ON TABLET PROPERTIES." International Journal of Pharmaceutical
Sciences and Research 5, no. 11 (2014): 4893.
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Pressure Chemical (PCC) currently custom produces fumaric acid derivatives.
Call us to discuss your needs for mono fumarate esters,
difumarate esters (di fumarate esters), and their salts.
Think of PCC for all of Your Fumarate Chemistry Needs
3419 Smallman Street, Pittsburgh, PA 15201  412-682-5882  www.presschem.com