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INHECO On Deck Thermal Cycler - ODTC®
Implementation of SiLA communication interface on
embedded mini PC
SiLA conference Sept. 22, 2014, Basel
Dr. Volker Lob
INHECO GmbH, 82152 Martinsried, Germany, [email protected]
Thermal Innovations & Products
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Content
•
Company
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ODTC®: On Deck Thermal
Cycler; Product Details
•
Hardware concept and
SiLA integration level
•
Challenges and Problems
•
Perspective
Thermal Innovations & Products
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Company - History
2000
INHECO founded by Guenter
Tenzler
2001
Focus on thermal products in lab
automation
2003
First PCR developments
2005
First IVD product development
2006
ISO 9001:2000 certified
2009
First IVD Project in the US
successfully completed, move to
new premises
2014
+50 employees
INHECO develops, manufactures and Distributes products
for thermo-mechanical applications.
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ODTC®: Designed for LabAutomation
Thermocycling
Heating
Cooling
Sealing
VCM® Technology
SiLA enables “plug and play” integration and guarantees cost- and timeeffective development of complex lab-platforms for high throughput
applications.
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Compact and Innovative Design for Optimal Deck Integration
Liquid handling platform
ODTC
P&CU
typical competitor product
•
Very low height to avoid
interference with gripper
or pipettor movement
•
Competitor products are
too large for proper ondeck integration
•
Power supply and
controller are located in a
separate box underneath
the deck
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Unique Thermal Performance with VCM®-Technology
• Almost ZERO well-to-well
temperature uniformity
• Almost ZERO delay-time during
PCR-Cycle
• Excellent well-to-well temperature
uniformity even with nonhomogeneous sample loading
• Still very good temperature
uniformity when lid is open
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Various Options for Plate Sealing
sealing mat
robot
manageable
sealing mat
sealing foil
•
•
Presealed disposables (e.g. sealing foils)
•
Sealing mat mounted in the lid, may be used
with presealed and unsealed disposables
(cross contamination issues must be
considered according to assay type)
Robot manageable sealing mats, pick-andplace with gripper
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Free programmable temperature curves
INHECO Skript Editor
•
•
Easy programming of thermo cycles
Input of process parameters:
o plate type
o filling level
o target temperature curve
 ramp speed,
 plateau temperature
 plateau time
• Free programmable temperature
curves from +4°C to +99°C
•
Lid can be opened and closed
during operation – pipetting during
thermocycle runs is possible
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Encapsulated hardware Module for SiLA communication
INHECO SiLA Module: Interfaces
SiLA
(TCP/IP)
low-level serial
communication
(RS232)
Benefits:
•
•
•
•
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High integration level
Size of a matchbox
Standard communication Interface (SiLA <–> RS232)
Encapsulated system (modular system architecture)
I/O Port for further device controlling/signaling
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ODTC® internal serial communikation (RS232)
Internal serial real-time interface (2 Layer)
This SiLA interface module makes integration into lab automation
systems very easy. Platform manufacturers and Third-PartyIntegrators can expand their product line functionality with minimal
configuration time and effort.
Thermal Innovations & Products
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ODTC® supports SiLA integration level 3
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Software (driver) with SiLA-Library on the
device
Easy replacement of devices
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No additional hardware required
Standard wiring to the PMS (Ethernet)
ODTC®
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ODTC® SiLA Commands
SiLA Device Class 30 (PCR Cycler, version: 1.2.01)
Commands:
-
9 Mandatory Commands
4 Required Commands
3 Optional Commands
4 Specific Commands
SiLA Command
Mandatory Required
Abort
×
DoContinue
×
GetDeviceIdentification
×
GetStatus
×
Initialize
×
LockDevice
×
Pause
×
Reset
×
UnlockDevice
×
GetParameters
×
PrepareForInput
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PrepareForOutput
×
SetParameters
×
Optional
ExecuteMethod
×
GetConfiguration
×
SetConfiguration
×
Specific
CloseDoor
×
OpenDoor
×
ReadActualTemperature
×
StopMethod
×
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Challenges and Problems
Challenges
• No SOAP Server within the .NET Compact Framework 3.5 (MS Visual Studio )
• Translation between managed (C#) and unmanaged Code (C++) -> Middleware
• Limited resources (embedded PC), space saving and runtime optimized
programming.
• Architecture encapsulate device-specific properties (device.dll)
Problems
• “Specific commands” dilute the standard
• Interpretation of the specification (e.g. RequestID unique during lifetime)
Successful Validation
1. Fraunhofer LACS (PMS)
2. Infoteam Library (Driver)
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Perspective
• SiLA certification for the INHECO SiLA Module
• Equip further INHECO Products with the SiLA -> e.g. new On Deck
Incubator Line (Scila)
SiLA
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Contact
ODTC® to be exhibited at MipTec 2014
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SiLA Live Integration Demo, booth # A 41/42
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Hamilton Robotics, booth # C 53
For further product Information please
contact:
INHECO GmbH
Frauenhoferstrasse 11
82152 Martinsried
Germany
Tel.: +49 89 899593 – 101
[email protected]
www.inheco.com
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