International Journal of Professional Holistic Aromatherapy
Transcription
International Journal of Professional Holistic Aromatherapy
ISSN 2167-8596 The International Journal of Professional Holistic Aromatherapy Fostering the education and practice of the professional holistic aromatherapist IJPHA Volume 1 Issue 4 Spring 2013 Yuzu and Dill Aromatherapy Benefits ANS Regulation for Elementary School Faculty East Meets West: An Integrated Viewpoint for the Skin for Aromatherapeutic Healing Psychospiritual Profiles of Citrus Oils Cancer Preventing Properties of Essential Oil Monoterpenes Beneficial Blending for Elder Care Essential Oils and Eye Care Case Study: Haemorrhoids www.ijpha.com Editor Lora Cantele, RA, CMAIA, CSRT [email protected] Editorial Advisory Committee Cindy Black, L.Ac. www.meridianmassageinstitute.com Andrea Butje, LMT, Clinical Aromatherapist www.aromahead.com Linda Byington, RA, Cert. Reflexologist Suzanne Catty, LHP, Clinical RA, Cert. Reflexologist www.newworldorganics.com Eileen Cristina, LMT, Clinical Aromatherapist [email protected] Debbie Freund, RN, CCAP From the Editor Spring is nearly here despite all the snow here in Boulder. It seems fitting that we would be working on an issue about citrus oils, and d-limonene in particular, to help cheer us. This issue takes a look at the therapeutic benefits of monoterpenes. Dr. Mark Brudnak discusses limonene as a chemopreventative agent and Dr. KangMing Chang strays from the often used Lavender (Lavandula angustifolia) to employ the stress-reducing benefits of Bergamot (Citrus bergamia) oil in his research study. We also profile the lesser-known Yuzu (Citrus junos) oil and Dill (Anethum vulgaris). Mindy Green, MS, RA, RH (AHG) www.greenscentsations.com Rhiannon Harris, FIFPA www.essentialorc.com Robert Tisserand, Essential Oil Consultant www.roberttisserand.com Publication Enhancements Aromatherapy LLC 5435 Indian Summer Ct Boulder, CO 80301—USA Tel: + 815 814 1444 Skype: lora.cantele Email: [email protected] Web: www.ijpha.com The IJPHA is published quarterly ISSN 2167-8588 Disclaimer The editor/publisher does not accept responsibility for the opinions, advice and/ or recommendations of its contributors. Furthermore, the IJPHA accepts no responsibility for any incident or injury to persons or property resulting from the use of any method, products, instructions or ideas contained within this publication. Advertising Acceptance of an advertisement by the IJPHA does not imply the endorsement or guarantee of quality by the IJPHA. Author Guidelines The IJPHA welcomes your articles and case studies for submission! Questions, articles, advertising and subscriptions inquiries may be submitted to the editor/ publisher. For information with regard to article submissions, advertising rates, and subscription, you may download our Media Kit and Writing Guidelines at: www.ijpha.com It always makes me smile when we find that we are a step ahead of the wave of topical posts on facebook. One of the most disturbing is the much discussed post from an independent essential oil distributor and her recommendation to use essential oils in the eyes as a natural means of eye care. Robert Tisserand provides the facts. Warning: the photo contained within the article is very disturbing. Spring cleaning is another online topic and Andrea Butje and Linda Byington have some great recipes to share with you for your own natural cleaning products. The IJPHA continues to provide new ways for you to “look outside the box.” Katharine Koeppen personifies the archetypes of citrus oils and Terese Miller discusses the skin from an East meets West perspective. One of our aims is to provide you with case studies and information from practitioners. Cynthia Loving shares her Sensible-Solutions Program for elder care and Sharon Falsetto offers her case study on the unpleasant topic of haemorrhoids. I encourage you to share your successes as well. I hope you have enjoyed our first volume of the IJPHA! With your journal is a reminder to renew your subscription. You can renew at our new website (www.ijpha.com) or send a check to the address at left. Lora Cantele On the cover: Yuzu [Citrus junos] Photo courtesy of Hiromi Suzuki © 2011 The contents of this journal are the copyright of the International Journal of Professional Holistic Aromatherapy (IJPHA) and may not be reprinted without permission of the IJPHA. The information contained herein may not necessarily represent IJPHA’s opinions or views. IJPHA Vol. 1 Issue 4 Spring 2013 3 In this issue 3 5 From the Editor Essential Oil Profile: Yuzu 9 Aromatherapy Benefits Autonomic Nervous System Regulation for Elementary School Faculty in Taiwan Kang-Ming Chang, PhD and Chuh-Wei Shen Lora Cantele, RA, CMAIA, CSRT 17 Anethum graveolens: A Traditional Indian Medicinal Herb and Spice Sayantan Jana, PhD and Gyan Singh Shekhawat, PhD 21 East Meets West: An Integrated Viewpoint of The Skin as an Avenue of Absorption and Healing in Aromatherapy Terese Miller, DOM, CA 25 Case Study: Using Essential Oils for the Management of Haemorrhoids Sharon Falsetto, Clinical Aromatherapist 27 Let the Sun Shine In: A Psychospiritual Profile of Popular Citrus Essential Oils Katharine Koeppen, RA, LMT, NCTMB 31 Cancer-Preventing Properties of Essential Oil Monoterpenes d-Limonene and Perillyl Alcohol Mark Brudnak, PhD, ND 37 Beneficial Blending for Elder Care: The Scents-ible Solutions Aromatherapy Program Cynthia Loving, Aromatherapist, LMT 43 Natural Spring Cleaning Andrea Butje, Clinical Aromatherapist and Linda Byington, RA, Certified Reflexologist 45 Blind Leading the Blind? Essential Oils in Eye Care Robert Tisserand, Essential Oil Consultant 47 Business Tip Andrea Butje, Clinical Aromatherapist 48 Book Review Anita James, SPdipA, MIFPA, Cert Ed. 49 Recipes from the Sensual Kitchen 50 Good To Know... 4 IJPHA Vol. 1 Issue 4 Spring 2013 Kris Wrede, Aromatic Alchemist Essential Oil Profile: Yuzu by Lora Cantele, RA, CMAIA, CSRT Yuzu © Bluhazejun/Flickr Yuzu (Citrus junos Sieb. ex Tanaka; Citrus ichangensis x C. reticulata var. austere) Other names: ch'êng tzu, xiang cheng, oranger du Kan-Sou, yujanamu Botanical family: Rutaceae Botany: Yuzu is believed to be a hybrid between Ichang papeda (Citrus ichangensis) and Satsuma mandarin. Yuzu grows on medium-sized trees, approximately 13-18 feet in height, with dense foliage similar to a bitter orange tree. The fruit, about the size of a mandarin orange, grows on thorny branches. The fruit rind is a green color that changes to yellow as it matures in October. The peel is bumpy and loose-fitting around the fruit itself. The flavor is sour like a lemon, but the rind is very fragrant and the fruits are often used to perfume the air. The Yuzu is the hardiest of the citrus fruits and can withstand temperatures as low as 10° F. History and traditional uses There has been some discussion regarding the origins of the Yuzu tree. Tyôzaburô Tanaka with the Imperial University wrote that it was thought to have originated in Korea and from there was introduced into China, eventually making its way into southern Japan during the Tang Dynasty in the 10th century A.D. (Taninaka, 1981). Still others insist that Yuzu originated in the upper reaches of the Yangtze river, in China (Rahman et al, 2001). In 1914, Frank N. Meyer, a plant explorer for the USDA, found Yuzu (which he originally named Kansu orange) growing wild in the southern part of Gansu province. He collected the seeds and sent them back to the United States. Later in 1922, Tanaka discovered that the Kansu orange was the same as the Yuzu that the US Department of Agriculture (USDA) had been propagating for several years. This suggests that Yuzu may have been imported prior to the 1900s by Japanese immigrants (Karp, 2003). Today there are many varieties and hybrids of Yuzu in Japan and China. The largest producers of Yuzu are Japan and Korea (Sawamura, 2005). Yuzu is commonly used for cooking in much the same way one would use the juice or rind of a lemon to enhance the flavor of soups, fish, sweet foods, and medicinal teas as the rind is so fragrant. The fruit is sour, like a lemon, and not normally eaten as a whole fruit. Ponzu is a tart, watery sauce made from mirin, seaweed, rice vinegar, and citrus, including Yuzu, and is used in Japanese cuisine (Abkenkar, 2003). A tisane or herbal tea can be made from steeping the fruit rind in hot water. The flavonoid naringenin, found in Yuzu, fruit has been found to be a useful chemopreventive agent against neurodegenerative diseases such as Alzheimer’s disease (Heo et al, 2004). There have been a few reported studies of the uses of essential oil of Yuzu peel in cosmetics and aromatherapy (Sawamura, 2005). Popular in the Japanese culture is a Yuzu bath. Traditionally this is done in connection with Toji (the winter solstice) as a preventative measure to ward off colds and seasonal ills. The fruits are wrapped in cheesecloth or simply cut in half and dropped into a tub of hot water. The oil from the fruit produces a tonic effect that stimulates the circulatory and digestive systems, making it useful for general aches and pains, rheumatism, and arthritis (Lyth G, 1997-2013). IJPHA Vol. 1 Issue 4 Spring 2013 5 Extraction information Country of origin: Japan, Korea, China Part of plant used: Fruit peel Extraction method: Cold expression Color of oil: Light green to pale yellow Blending information Odor description: Sweet aroma of blended citrus scents of grapefruit, bergamot, mandarin, and lime. Among the most odor-active volatiles in Yuzu, (E)-non-6-enal and Yuzunone were identified for the first time only in Yuzu peel oil and not in the peel of other citrus species, and greatly contribute to the distinct aroma of Yuzu (Miyazawa N et al, 2009). Notes: Middle-Top, Top Safety Yuzu essential oil may be photosensitizing. Older, oxidized oils have the potential for skin irritation similar to other citrus oils and oils high in monoterpenes like conifers. Chemical constituents Chemical feature: The essential oil is characterized by a high percentage of monoterpene hydrocarbons, predominantly d-limonene, γ-terpinene, β-phellandrene, myrcene, linalool, and α-pinene. While there is not a lot written about Yuzu, and research is limited, its chemical profile is very similar to Mandarin (Citrus reticulata) with the addition of β-phellandrene which adds to its unique aroma. Chemical profile for Yuzu (Citrus junos) Chemical family Monoterpenes Components Monoterpenols d-limonene 75.77, γ-terpinene 8.79, β-phellandrene 3.09, β-myrcene 1.79, α-pinene 1.25, para-cymene 1.19, β-pinene 0.72, α-phellandrene 0.47, terpinolene 0.47, α-thuyene 0.33, α-terpinene 0.26, sabinene 0.20, trans-β-ocimene 0.18 β-farnesene 0.59, bicyclogermacrene 0.26, β-caryophyllene 0.20, germacrene D 0.16 linalol 2.21, α-terpineol 0.25, terpinen-4-ol 0.18 Sesquiterpenols spathulenol 0.43 Phenols thymol 0.15 Sesquiterpenes GC/MS obtained from www.aromaticsinternational.com. Yuzu from Japan distilled Summer 2012. 6 IJPHA Vol. 1 Issue 4 Spring 2013 Therapeutic properties Antidepressant, anti-inflammatory, antiseptic, antispasmodic, antiviral, bactericidal, carminative, digestive system tonic/stimulant, expectorant, lipolytic, sedative, stomachic *Actions highlighted in bold print are referenced under 'Research.' Research The anti-inflammatory effects of limonene from yuzu peel were examined with human eosinophilic leukemia HL-60 clone 15 cells. The results suggest that limonene may have potential anti-inflammatory efficacy for the treatment of bronchial asthma by inhibiting cytokines, Reactive Oxygen Species (ROS) production, and inactivating eosinophil migration (Hirota R et al, 2010). Yuzu essential oil inhibits the formation of N-nitrosodimethylamine (NDMA), a highly toxic contaminant found in drinking water and vegetables (Sawamura et al, 1999; 2005). Yuzu was found to be potentially more lipolytic (breaks down stored fat) than the popular raspberry ketones. Lipolytic effect was found to be high when the oils included a higher content of gammaterpinene and para-cymene. Limonene showed potential lipolytic effect, and its effect is likely to be enhanced by the presence of gamma-terpinene and para-cymene (Choi H S, 2006). Formulas using Yuzu Uplifting synergy 5 ml Yuzu (Citrus junos) 5 ml Petitgrain sur fleur (Citrus aurantium var. amara fol. and flos.) 4 ml Lavender (Lavandula angustifolia) 3 ml Sandalwood (Santalum austrocaledonicum) 3 ml Kaffir lime/Combava (Citrus hystrix) Use this synergy in a diffuser or aromatic jewelry. Add a few drops to your bath or mix 36 drops into 4 ounces/120 ml of unscented lotion or shower gel. Inhaler for anxiety 2 drops Jasmine (Jasminum grandiflorum) 13 drops Yuzu (Citrus junos) Add the blend of essential oils to a blank inhaler. Inhale deeply, several times, through each nostril. Use as needed. Chest rub for cough and cold 4 oz/120 ml unscented white cream or carrier oil 12 drops Eucalyptus (Eucalyptus smithii) 6 drops Hyssop (Hyssopus officinalis var. decumbens) 3 drops Rosemary (Rosmarinus officinalis) 3 drops Yuzu (Citrus junos) Apply the blended cream to chest, neck, and shoulders twice daily. Gargle for throat infection 2 drops Sandalwood (Santalum paniculatum) 2 drops Yuzu (Citrus junos) At the onset of symptoms, add essential oils to a 4 ounce/120 ml glass of water and gargle with the mixture every few hours. Be sure to stir the mixture well before each mouthful and spit after each cycle of gargling. References Abenkar A and Isshiki. (2003). Molecular characterization and genetic diversity among Japanese acid citrus (Citrus spp.) based on RAPD markers. J of Horticulture Science and Biotechnology. (78) 1, p108-112. Choi H S. (2006). Lipolytic effects of citrus peel oils and their components. J Agric Food Chem. 54 (9), p3254-8. Dr. Duke's Phytochemical and Ethnobotanical Databases. [Online Database] Last accessed 8 Febuary 2013. Hanelt P, Editor. (2001). Mansfeld's encyclopedia of agricultural and horticultural crops. New York: Springer. Karp D. (2003). The Secrets Behind Chef's Not-So-Secret Ingredient. The New York Times. http://www.nytimes.com/2003/12/03dining/03 YUZU.html?ex=1385787600&en=503d5cd5111f4124&ei=5007& partner=USERLAND. Last accessed 18 February 2013. Lyth G. (1997-2013). http://www.quinessence.com/yuzu.htm Miyazawa N et al. (2009). Novel character impact compounds in Yuzu (Citrus junos Sieb. ex Tanaka) peel oil. J. Agric Food Chem. 57 (5), p1990-6. Rhaman M M, Nito N, and Isshiki S. (2001). Cultivar identification of 'Yuzu' (Citrus junos Sieb. ex Tanaka) and related acid citrus by leaf isozymes. Scientia Horticulturae. 87, p191-8. Sawamura M, Sun S H, Ozaki K, Ishikawa J, Ukeda H. (1999). Inhibitory effects of citrus essential oils and their components on the formation of N-nitrosodimethylamine. J Agric Food Chem. 47(12), p4868-72. Sawamura M, Wu Y, Fujiwara C, Urushibata M. (2005). Inhibitory effect of yuzu essential oil on the formation of Nnitrosodimethylamine in vegetables. J Agric Food Chem. 53(10), p4281-7. Taninaka T, Otoi N, Morimoto J. (1981). Acid citrus cultivars related to the yuzu (Citrus junos Sieb. ex Tanaka) in Japan. Proceedings of the International Society of Citriculture. Edited by Matsumoto K, Oogaki C, and Kozaki I. Tokyo, Japan: Aiko Printing Co. p73-76. University of California, Riverside. http://www.citrusvariety.ucr.edu/ citrus/yuzu1.html Lora Cantele is a Registered Clinical Aromatherapist and aromatherapy educator. www.enhancedgifts.com Practitioner share from Liz Fulcher, Clinical Aromatherapist and Educator www.aromaticwisdominstitute.com Digestive Blend (To aid digestion and settle a gassy belly) 3 drops Cardamom (Ellettaria cardamomum) 3 drops Roman Chamomile (Chamaemelum nobile) 3 drops Yuzu (Citrus junos) 2 drops Clove (Syzygium aromaticum) 2 ounces Jojoba oil Blend the essential oils into the Jojoba oil and gently massage the blend into your belly clockwise after meals. Heo H J et al. (2004). Effect of antioxidant flavanone, naringenin, from Citrus junos on neuroprotection. Journal of Agri and Food Chem. 52 (6), p1520-5. Hirota R, Roger N N, Nakamura H, Song H S, Sawamura M, Suganuma N. (2010). Anti-inflammatory effects of limonene from yuzu (Citrus junos Tanaka) essential oil on eosinophils. Journal of Food Sci. © Liz Fulcher 2013 IJPHA Vol. 1 Issue 4 Spring 2013 7 8 IJPHA Vol. 1 Issue 4 Spring 2013 Aromatherapy Benefits Autonomic Nervous System Regulation for Elementary School Faculty in Taiwan Kang-Ming Chang1,2 Chuh-Wei Shen1,3 1 Department of Photonics and Communication Engineering, Asia University, Taichung, Taiwan, ROC. 2 Graduate Institute of Clinical Medical Science, China Medical University, Taichung, Taiwan, ROC. 3 Ming-Chien Elementary School of Nantou County, Taiwan, ROC. Abstract Workplace stress related illness is a serious issue. Thus, many stress reduction methods have been investigated. Aromatherapy applications of steamdistilled essential oils by inhalation or massage are typically used by populations that work under high stress. Elementary school teachers are a high-stress working population in Taiwan. In this study, 54 elementary school teachers from three schools were recruited to evaluate aromatherapy’s performance on stress reduction. Subjects with a history of asthma, high blood pressure or heart disease were excluded. Bergamot (Citrus bergamia) essential oil was used as an aromatherapy diffuser mist for ten minutes. Blood pressure and autonomic nervous system parameters were recorded five minutes before and after the application of the diffuser mist. Results showed that there were significant decreases in blood pressure, heart rate, low frequency (LF) power percentage and LF/HF while there were increases in heart rate variability and high frequency (HF) power percentage (p<0.001***) after application of the aromatherapy mist. Further analysis was investigated by dividing subjects into three background variables (position variables, age variables, gender variables) and anxiety degree groups. Anxiety degree groups were determined by the Beck Anxiety Inventory (BAI). All parameters were significantly different for most sub-groups, except for the substitute teachers and the light-anxiety group. Parasympathetic nervous system activation was measured after aromatherapy in this study. It encouraged further study of aromatherapy for other stressed working populations. Bergamot © Klaus Reger Introduction Workplace stress has attracted much attention recently (Whalen, 2009). In Taiwan, working stress is increasing among elementary school teachers as a result of students declining, competition between schools and education reform. Local studies have indicated that there is higher job stress and interpersonal stress in male elementary teachers than in female teachers. Young teachers feel increased stress on income and time scheduling, while senior teachers feel increased stress on colleague relationships (Hawng, 1999). Thus, appropriate stress coping methods are also highly desirable. Various approaches have been involved in workplace stress management (Shader et al, 2001). Aromatherapy, due to easy implementation and effectiveness, is one of them (Blevi and Sween, 1993). Essential oils are used to reduce body tension and emotional stress. Common essential oils are Bergamot (Citrus bergamia), Lavender (Lavandula angustifolia), and Geranium (Pelargonium graveolens) (Mein, 1998). Use of Lavender and Rosemary scented candles have been found to reduce the pressure of testing on nursing school students (McCaffrey et al, 2009). Aromatherapy was widely used for stress adaptation. Komarova and Avilov’s results showed that regular use of fragrant scented candles can increase students’ parasympathetic rhythm (Komarova and Avilov, 2009). Seo thought aromatherapy by inhalation was an effective stress management method. In a study when 36 female high school students received the aroma treatment, their stress levels were significantly lower (Seo, 2009). In addition, Hur and associates applied aromatherapy massage in Korean climacteric IJPHA Vol. 1 Issue 4 Spring 2013 9 women. Lavender, Rose Geranium (species not specified), Rose (Rosa damascena) and Jasmine (species not specified) with an essential oil 4:2:1:1 ratio, in almond (Prunus dulcis) oil (90%) and evening primrose (Oenothera biennis) oil (10%) at a concentration of 3% used for massage once a week. Eight weeks of massage showed a significantly lower total menopausal index than that in wait-listed controls. These findings suggest that aromatherapy massage can be an effective treatment of menopausal symptoms such as hot flushes, depression and pain in climacteric women (Hur et al, 2008). Bagetta and associates examined the brain wave spectrum power and found that Bergamot essential oil correlates well with its exocytotic and carrier-mediated release of discrete amino acids endowed with neurotransmitter function in the mammalian hippocampus (Bagetta et al, 2010). Bergamot essential oil was able to interfere with normal and pathological synaptic plasticity. Therefore, Bergamot essential oil was effective for anxiety reduction of mild depression subjects. It also had the effect of reducing pain in cancer subjects (Narita et al, 2007). Therefore Bergamot essential oil is used in this study, with the aid of a misting diffuser for aromatherapy. Many essential oils have a sedating effect, such as Bergamot, Lavender, Chamomile (species not specified), and other essential oils (Mein, 1998). Chamomile was expensive and the odor of Lavender was irritating and allergenic to a portion of the subjects so Bergamot essential oil was chosen for this study. The autonomic nervous system includes sympathetic activity and parasympathetic activity. When people feel anxious or experience stress, heart rate and sympathetic activity will increase and parasympathetic activity will decrease. Narita and associates found that there were higher sympathetic activities for depressed and anxious subjects than for normal subjects (Narita et al, 2007). Similar results were also shown on swimmers (Cervantes et al, 2009). Autonomic nervous system activities were monitored from heart rate variability (HRV) which was derived from heartbeat interval time series. With further discrete Fourier transform (DFT*) applied to the heartbeat interval time series, two specific power spectrum ranges were defined. One is low 10 IJPHA Vol. 1 Issue 4 Spring 2013 frequency range (LF, 0.04-0.15 Hz), and the other is high frequency range (HF, 0.15-0.4 Hz). *DFT is used to convert the sampled function from its original domain (often time or position along a line) to the frequency domain. Because it deals with a finite amount of data, it can be implemented in computers by numerical algorithms or even dedicated hardware (www.Wikipedia.org). Thus, significant HRV variation was expected after aromatherapy. Sympathetic activity is accompanied with increases in low frequency power (LF) of the heart rate variability (HRV) spectrum, while parasympathetic activity is associated with high frequency power (HF). Duan and associates' results indicated that after the inhalation of Lavender, there was a significant increase in HF and LF/HF values (Duan et al, 2007). Anxiety caused by anxiety-provoking film clips was reduced with the aid of orally administered Lavender essential oil and there was an increase in HRV (Bradley et al, 2009). Therefore HRV was used as an indicator to measure the effect of aromatherapy on elementary school teachers. Material and methods Subjects Fifty-four elementary school teachers from three different schools were enrolled. Possible asthma, hypertension or heart disease patients were excluded. The reason to exclude asthma is that the diffuser mist may induce an asthma attack, so asthmatic subjects were excluded from this experimental study. Many studies indicate that heart rate variability is closely related to heart disease, myocardial infarction and heart failure. Therefore the subjects with heart disease and hypertension were also excluded from this study. Further subgroups were divided by gender, job position, age and degree of anxiety. The Beck Anxiety Inventory (BAI) was used by a qualified expert to estimate the degree of anxiety in each volunteer. Based on the BAI result, subjects were scored as light anxiety, mild anxiety or moderate anxiety. Detailed subject information is listed in Table 1. Position Administrative Staff (n=19); Homeroom Teacher (n=21); Substitute Teacher (n=14) Gender Male (n=25); Female (n=29) Age C—Ten minute aromatherapy intervention was conducted by the same nurse, as demonstrated in Figure 1. Respiration rate and respiration volume in this session were required the same as that during the rest period. Below 34 (n=21); 35-44 (n=19); Above 45 (n=14) Anxiety Degree Light (n=26); Mild (n=17); Moderate (n=11) Table 1 Subject information (n=54) Experimental procedures Aromatherapy was conducted once a week. Physiological recordings were taken during the second week in the school’s health center. An Ultrasonic Ionizer Aromatherapy Diffuser was used for aroma evaporation (type YHL668/I, ultrasound frequency 2.5MHz, Nature Creart Co. Ltd, made in Taiwan). 100% pure Bergamot essential oil was used and diluted to 2%. Physiological parameters were recorded by an ANSWatch® monitor (TS-0411 type, Taiwan Scientific Ltd., which has been approved by ISO 13485, and EU CE Mark). Each session was recorded for seven minutes. Average blood pressure and HRV parameters were shown on the panel of ANSWatch® monitor. Detail experimental procedures were as follows. IRB was approved by Asia University Medical Research Ethics committee. A—Basic subject information was collected: height, weight, body mass index (BMI), and age range. Each subject was required to fill in a consent form and a BAI survey. First and second aromatherapies were conducted at the same time on the same day of the week. Use of cigarettes, alcohol and coffee consumption were forbidden six hours before aromatherapy. B—Subjects were asked to rest for five to ten minutes before HRV recording. Then a pre-test recording of seven minutes was made while the subject was seated with eyes open and not engaged in any activity. Misting diffuser and ANSWatch® © 2011 K-M Chang and C-W Shen Fig. 1 D—Post-test recording for another seven minutes. Physiological parameter collection ANSWatch® monitor records two blood pressure parameters and five HRV parameters, as shown below: A—SYS (mmHg): Systolic blood pressure. B—DIA (mmHg): Diastolic blood pressure. C—HR (BPM): Average heart beat in terms of beats per minutes (BPM). D—HRV (ms): Heart rate variability, a similar term to SDNN, defined as standard derivation of RR interval sequence. E—HF(%): High frequency power percentage. HF frequency range was between 0.15-0.4 Hz on heart rate variability spectrum. F—LF(%): Low frequency power percentage. LF frequency range was between 0.04-0.15 Hz on heart rate variability spectrum. G—LF/HF: Ratio of LF power to HF power. IJPHA Vol. 1 Issue 4 Spring 2013 11 Statistics In this study, the SPSS 12.0 software package was used to conduct data analysis. Significance test for the alpha value was set at 0.05. Several statistical methods were used, as follows: A—Descriptive statistics: Personal information on subjects is represented as mean ± standard deviation (mean ± SD). B—Paired t-test: Intra-group differences among three background variables "gender," "age" and "position" were compared. Seven parameters within each group, SYS, DIA, HR, HRV, HF%, LF% and LF/ HF were examined. C—Analysis of Covariance (ANCOVA): Pretest was used as covariates, inter-group difference among position, age, gender and anxiety degree was examined by ANCOVA. The Scheffe method and the Post hoc test for least significance difference test were used for post hoc test. A three-way ANCOVA was also used to examine the interaction effect among the three background variables "gender," "age" and "position." Results Paired t-test results for Bergamot essential oil treatments for all subjects are listed in Table 2. According to Table 2, it is apparent that after the aromatherapy treatment, blood pressure is reduced both on SYS and on DIA. There was also a decrease in heart rate, LF% and LF/HF. Apparently, treatment of aromatherapy increases parasympathetic nervous activity; therefore HF and HRV parameters will increase. Further analysis of subgroups is shown in the following: The position group result is shown in Table 3. Similar to Table 2, there were significant differences on all physiological parameters for administrative staff and for home room teachers. Although there was also a significant reduction in blood pressure and heart rate, there was not enough statistical difference on HF% and LF% for the substitute teachers. According to further in-depth interviews with substitute teachers, the previous result may be associated with the coming annual faculty entrance test. Substitute teachers had to prepare for the test in their spare time and they could not relax; therefore aromatherapy’s impact is reduced. 12 IJPHA Vol. 1 Issue 4 Spring 2013 Items All SYS Before 123.30±12.810 (mmHg) After 112.78±15.909 DIA Before 82.91±7.86 (mmHg) After 76.76±7.997 HR Before 83.15±13.964 (BPM) After 74.61±9.803 HRV Before 137.54±69.215 (ms) After 197.89±91.195 HF Before 50.93±15.331 (%) After 61.13±10.622 LF Before 49.57±15.320 (%) After 38.37±10.010 LF/HF Before 1.170±0.8348 After 0.648±0.2800 P value 0.001*** 0.000*** 0.000*** 0.000*** 0.004** 0.004** 0.005** p<0.05*; p<0.01**; p<0.001*** Table 2 Paired t-test result for aroma for all subjects Items SYS Administrative Homeroom Substitute Staff (n=19) Teacher Teacher (n=21) (n=14) 123.10±14.74* 123.79±12.50** 111.16±15.74 113.43±17.10 114.00±15.27 Before 82.37±7.32** 82.00±8.78** 85.00±7.26** 76.10±7.91 77.86±7.02 Before 123.16±11.34 (mmHg) After DIA (mmHg) After 76.68±9.05 HR Before 83.42±12.37 ** 84.71±17.78* 80.43±9.21** (BPM) After 76.57±10.34 73.29±9.29 HRV Before 138.84±79.54** (ms) After HF Before 48.95±16.54** 52.86±12.23* 50.71±18.37 (%) After 60.10±8.01 59.07±16.04 LF Before 51.05±16.54** 47.14±12.23* 49.29±18.37 (%) After 35.42±6.19 39.90±8.01 40.93±16.04 LF/HF Before 1.33±.99** 0.99±0.48* 1.22±1.02* After 0.71±0.25 0.72±0.48 73.42±9.71 147.38±63.93** 121.00±63.48** 216.26±108.82** 205.67±71.53 64.58±6.19 0.56±0.146 161.29±87.21 p<0.05*; p<0.01**; p<0.001*** Table 3 Position subgroup paired t-test result for aroma Subgroup results for age and gender are listed in Table 4 and Table 5, respectively. There were significant differences due to aromatherapy for all subgroups on all physiological parameters. The subgroup with anxiety is also tested and shown in Table 6. The high anxiety and moderate anxiety groups had similar results to those shown in Table 2. Aromatherapy was effective for high anxiety and moderate anxiety groups. The light anxiety group had the same performance as the substitute teacher group. There was no statistical difference on HF% and LF%, but there were significant differences for the other five parameters. After further checking of population distribution, there was no population overlap between the light anxiety group and the substitute teacher group. The light anxiety was not fully affected by aromatherapy. A possible reason may be the stable autonomic nervous system for the light anxiety group; thus there was no further activation of parasympathetic activity. Analysis of covariance between age and position groups was evaluated. There was no significant difference for all seven physiological parameters. Similar results were also shown for the covariance analysis between gender and anxiety degree groups. In other words, aromatherapy performance was similar for all these groups. 35-44 (n=19) Above 45 (n=14) 119.32±15.26* 127.00±12.29** 114.24±11.49 109.26±20.99 115.36±13.78 Before 82.62±7.18 ** 81.11±7.26** 85.79±9.26** 73.95±7.95 79.50±9.69 Items SYS Before 124.43±10.06** (mmHg) After DIA Below 34 (n=21) (mmHg) After 77.48±6.19 HR Before 80.71±10.52** 87.42±18.04* 81.00±11.52** (BPM) After 77.00±11.16 74.86±9.74 HRV Before 131.86±70.25** 172.37±72.99** 98.79±33.48** (ms) After 190.10±98.56 232.84±97.32 162.14±50.86 HF Before 51.52±16.46* 51.89±15.51* 48.71±14.18* (%) After 60.95±11.22 61.36±8.64 LF Before 48.48±16.46* (%) After LF/HF 72.29±8.36 62.33±10.03 37.67±10.03 48.11±15.51* Male (n=25) Female (n=29) SYS Before 124.52±11.31 ** 122.24±14.086** (mmHg) After 114.04±17.29 111.69±14.837 DIA Before 82.00±6.89** 83.69±8.652** (mmHg) After 77.32±8.72 76.28±7.440 HR Before 81.28±11.50** 84.76±15.813** (BPM) After 73.24±8.82 75.79±10.584 HRV Before 124.08±71.86** 149.14±65.883** (ms) After 191.56±102.44 203.34±81.740 HF Before 49.12±17.74** 53.28±12.029** (%) After 61.08±11.84 61.24±8.967 LF Before 50.88±17.74** 46.72±12.029** (%) After 38.92±11.84 38.76±8.967 LF/HF Before 1.30±1.017** 0.993±0.5451** After 0.66±0.35 0.672±0.2658 p<0.05*; p<0.01**; p<0.001*** Table 5 Gender subgroup paired t-test result for aroma Items Light(n=26) Mild (n=17) Moderate (n=11) SYS Before 119.19±11.90* 121.94±13.08** 135.09±6.49* (mmHg) After 110.19±18.84 111.88±12.47 120.27±11.16 DIA Before 82.92±7.63** 80.88±8.63** 86.00±6.72* (mmHg) After 76.73±8.19 75.47±7.238 78.82±8.94 HR Before 85.77±16.22** 81.82±13.12** 79.00±7.77* (BPM) After 76.19±10.25 74.00±9.507 71.82±9.30 HRV Before 160.19±64.25** 112.65±71.38** 122.45±65.42** (ms) After 222.65±95.88 178.47±85.98 169.36±78.34 HF Before 54.19±17.28 49.94±11.64** 44.73±14.52** (%) After 61.35±10.96 63.41±6.90 59.36±11.80 LF Before 45.81±17.28 50.06±11.64** 55.27±14.52** (%) After 38.65±10.96 36.59±6.90 40.64±11.80 LF/HF Before 1.09±1.02* 1.13±0.58** 1.418±0.67** After 0.627±0.23 0.61±0.18 0.764±0.45 p<0.05*; p<0.01**; p<0.001*** Table 6 Anxiety degree subgroup paired t-test result for aroma 51.29±14.18* 39.05±11.22 38.64±8.64 Before 1.200±0.87** 1.12±0.962* 1.200±0.618** After 0.62±0.21 0.679±0.27 0.66±0.35 Items p<0.05*; p<0.01**; p<0.001*** Table 4 Age subgroup paired t-test result for aroma Discussion High workplace stress is an important personal health risk factor; it can also be detrimental to the interests of the employer. An employer benefits from the reduced cost of having healthier employIJPHA Vol. 1 Issue 4 Spring 2013 13 ees, resulting in better education and service provided for students. As a high work-related stress group, elementary school teachers were chosen in this study as the experimental group. In this study, physiological signals were measured after the second once-weekly aromatherapy treatment. This experiment focused on the short-term stress relaxing effect instead of tracking the long-term effect of aromatherapy. Data showed that aromatherapy would be effective in promoting parasympathetic activation, reducing blood pressure and lowering heart rate. Therefore, aromatherapy may be useful to provide relief from working stress. Further subgroup analysis revealed that aromatherapy was also effective on groups arranged by gender, age and job positions. The personal characteristics that were found in association with aromatherapy performance included the degree of anxiety measured using the BAI. This study also found that aromatherapy was effective for moderate to severe anxiety groups. There was no significant statistical effect for the light anxiety group, which was stable for autonomic nervous activity. The function of aromatherapy is to drive the autonomic nervous activity toward a balanced state; therefore, there was limited physiological change after aromatherapy treatment. Whether or not aromatherapy is beneficial for long-term anxiety reduction is still an open issue. Bergamot essential oil is a good choice for aromatherapy, although there are many studies using lavender oil. Lavender oil was not chosen due to some subject’s report of allergy to lavender oil. Bergamot essential oil is more moderate for users and is lower in price. In the future, aromatherapy used in an air-conditioned environment could be beneficial by creating a better working environment. Many studies have confirmed that aromatherapy was useful for stress reduction, which is not only limited to inhalation of diffuser mist, but also transdermal application (Heuberger et al, 2008; Hongratanaworakit, 2009). This study further investigated aromatherapy on different variables in faculty, such as gender, age, position and level of anxiety. A control group with a water-only mist as a placebo is expected in a future study. The other factor that may 14 IJPHA Vol. 1 Issue 4 Spring 2013 affect aromatherapy performance is the odor preferences of different individuals. A subject's personal likes or dislikes could lead to different results. This was not factored in this study. It could be interesting to examine this in a future experiment. Conclusion After exposure to two 10-minute aromatherapy diffuser mists with Bergamot essential oil on elementary school teachers, the parasympathetic nervous system was enhanced and shown on corresponding physiological parameters. Use of essential oils seems to drive autonomic nervous activity toward a balanced state. Subjects with moderate and high degrees of anxiety benefited more than the light anxiety group. With strict control of experimental environment, including subject’s posture, measurement location and time, and experimental procedures, this study rules out many possible factors that affect the body's physiological signals. This article provides useful information about aromatherapy stress reduction performance on different faculty groups. These findings encourage further study of the effects of essential oils on the stress levels of employees in the workplace. Acknowledgement This work has been partly supported by the National Science Council of Taiwan (grant number NSC 982221-E-468-009-) and Asia University, Taiwan (grant number 98-ASIA-06-1). References Bagetta G, Morrone L A, Rombolà L, Amantea D, Russo R, Berliocchi L et al. (2010). Neuropharmacology of the essential oil of bergamot. Fitoterapia. 81(6), p453-461. Blevi V and Sween G. (1993). Aromatherapy. Avon Books. Bradley B F, Brown S L, Chu S, Lea R W. (2009). Effects of orally administered lavender essential oil on responses to anxiety-provoking film clips. Hum Psychopharmacol. 24(4), p319-330. Cervantes Blásquez J C, Rodas Font G, Capdevila Ortís L. (2009). Heart -rate variability and precompetitive anxiety in swimmers. Psicothema. 21(4), p531-536. Duan X, Tashiro M, Wu D,Yambe T, Wang Q, Sasaki T et al. (2007). Autonomic nervous function and localization of cerebral activity during lavender aromatic immersion. Technol Health Care. 15(2), p69-78. Hawng I L. (1999). Study on the Elementary and Part-time Administrative Teachers Work-load Pressure and Their Methods of Accommodation. Master thesis, National Pingtung Unv. of Education, Taiwan. Heuberger E, Ilmberger J, Hartter E, Buchbauer G. (2008). Physiological and behavioral effects of 1,8-cineole and (±)-linalool: a comparison of inhalation and massage aromatherapy. Nat Product Commun. 3(7), p1103 -1110. Hongratanaworakit T. (2009). Relaxing effect of rose oil on humans. Nat Product Commun. 4(2), p291-296. Hur M H, Yang Y S, Lee M S. (2008). Aromatherapy Massage Affects Menopausal Symptoms in Korean Climacteric Women: A PilotControlled Clinical Trial. eCAM. 5(3), p325-328. Komarova I A, Avilov O V. (2009). Individual olfactory responses of students repeatedly exposed to essential oils. Vopr Kurortol Fizioter Lech Fiz Kult. March-April (2), p33-36. McCaffrey R, Thomas D J, Kinzelman A O. (2009). The effects of lavender and rosemary essential oils on test-taking anxiety among graduate nursing students. Holist Nurs Pract. 23(2), p88-93. Mein C. (1998). Releasing Emotional Patterns with Essential Oils. Rancho Santa Fe:Vision Ware Press. Narita K, Murata T, Hamada T, Takahashi T, Omori M, Suganuma N et al. (2007). Interactions among higher trait anxiety, sympathetic activity, and endothelial function in the elderly. J Psychiatr Res. 41(5), p418-427. Seo J Y. (2009). The effects of aromatherapy on stress and stress responses in adolescents. J Korean Acad Nurs. 39(3), p357-365. Shader K, Broome M E, Broome C D, West M E, Nash M. (2001). Factors influencing satisfaction and anticipated turnover for nurses in an academic medical center. J Nurs Adm. 31(4), p210-216. Whalen K S. (2009). Work-related stressors experienced by part-time clinical affiliate nursing faculty in baccalaureate education. Int J Nurs Educ Scholarsh. 6(1), Article 30. Kang-Ming Chang received a Ph.D. degree in the Dept. of Electrical and Control Engineering at the National Chiao-Tung University, Hsinchu, Taiwan, R.O.C., in 2006. Since 2006, he has served as Assiciate Professor in the Department of Photonics and Communication Engineering, Asia University, Taichung, Taiwan, R.O.C. His current research interest includes biomedical signal processing on aroma, sleep, meditation and traditional Chinese medicine pulse wave analysis. Co-author, Chuh-Wei Shen, is master student to Dr. Chang. Reach practitioners around the world. Advertise in the IJPHA www.aroma-jsa.jp www.aroma-jsa.jp/english Japanese Society of Aromatherapy (JSA) is a group of medical professionals organized to promote and increase the level of awareness of medical aromatherapy, to establish aromatherapy as an academic discipline through scientific and medical research, to prevent aromatherapy malpractice accidents, to increase knowledge and skills through information exchange and sharing, and to improve members’ social positions. IJPHA Vol. 1 Issue 4 Spring 2013 15 16 IJPHA Vol. 1 Issue 4 Spring 2013 Anethum graveolens: A Traditional Indian Medicinal Herb and Spice Sayantan Jana, PhD and Gyan Singh Shekhawat, PhD © Pharmacognosy Reviews Abstract Dill (Anethum graveolens L.) has been used in Ayurvedic medicine since ancient times. It is a popular herb widely used as a spice and also yields an essential oil. It is an aromatic and annual herb of the apiaceae family. The Ayurvedic uses of dill seeds are carminative, stomachic and diuretic. There are various volatile components of dill seeds and herb, carvone being the predominant odorant of dill seed and α-phellandrene, limonene, dill ether, and myristicin being the most important odorants of dill herb. Other compounds isolated from the seeds are coumarins, flavonoids, phenolic acids and steroids. The main purpose of this review is to understand the significance of Anethum graveolens in Ayurvedic medicine and non-medicinal purposes with an emphasis given to the enhancement of secondary metabolites of this medicinal plant. Introduction The genus name Anethum is derived from the Greek word 'aneeson' or 'aneeton,' which means 'strong smelling.' Its common use in Ayurvedic medicine is in abdominal discomfort, colic and promoting digestion. Ayurvedic properties of shatapushpa are katu tikta rasa, usna virya, katu vipaka, laghu, tiksna, and snigdha gunas. It cures ‘vata,’ ‘kapha,’ ulcers, abdominal pains, eye diseases and uterine pains. Charaka prescribed the paste of linseed, castor seeds and Shatapushpa (A. graveolens) pounded with milk for external applications in rheumatic and other swellings of joints. Kashyapa Samhitaa attributed tonic, rejuvenating and intellect promoting properties to the herb A. graveolens. It is used in Unani medicine in colic, digestive problem and gripe water (Khare, 2004). Anethum graveolens L. is used in the preparations of more than 56 Ayurvedic preparations which include Dasmoolarishtam, Dhanwanthararishtam, Dill © Holistic Photo Mrithasanjeevani, Saraswatharishtam, Gugguluthiktaquatham, Maharasnadi kashayam, and Dhanwantharam quatham (Ravindran and Balachandran, 2005). Anethum graveolens L. is believed to be a native of Southwest Asia or Southeast Europe (Bailer et al, 2001). It is indigenous to the Mediterranean, Southern USSR and Central Asia. Since Egyptian times, Anethum has been used as a condiment and also for medicinal purposes (Quer, 1981). It was used by Egyptian doctors 5000 years ago and traces have been found in Roman ruins in Great Britain. In the Middle Ages it was thought to protect against witchcraft. Greeks covered their heads with dill leaves to induce sleep. Botanical description Anethum graveolens L. is the sole species of the genus Anethum, though classified by some botanists in the related genus Peucedanum as Peucedanum graveolens L. (Pulliah, 2002). A variant called east Indian dill or Sowa (Anethum graveoeloens var sowa Roxb. ex, Flem.) occurs in India and is cultivated for its foliage as a cold weather crop throughout the Indian subcontinent, Malaysian archipelago and Japan. Cultivation Dill prefers rich well-drained, loose soil and full sun. It tolerates a pH in the range 5.3 to 7.8. It requires warm to hot summers with huge sunshine levels; even partial shade will reduce the yield substantially. The plant quickly runs into seeds in dry weather. It often self-sows when growing in a suitable position. Propagation is through seeds (Pulliah, 2002). Seeds are viable for 3–10 years. The seed is harvested by cutting the flower heads off the stalks when the seed is beginning to ripen (Figure 1). IJPHA Vol. 1 Issue 4 Spring 2013 17 (a) Seeds, (b) plants (c) inflorescence © Pharmacognosy Reviews Applications Ecological importance of the species: The herb is a good companion for corn, cabbage, lettuce and onions but inhibits growth of carrots. Dill reduces a carrot crop if it is grown to maturity near them. However, the young plant will help to deter carrot root fly. Sustainable production of fennel and dill by intercropping indicates that the presence of dill exerts a stabilizing effect on fennel seed yield. Insects, bees and wasps are attracted to the yellow flowers of Anethum for plant resources like nectar and pollens. Coriander and dill, when planted together, have a very remarkable pest control benefit (Carrubba et al, 2007). Intercropping with flowering herbaceous plants increases parasitoid survivorship, fecundity and retention, and pest suppression in agro ecosystems. Dill is a potentially suitable host for the parasitoids Edovum puttleri Grissell, Cotesia glomerata and Pediobius foveolatus Crawford (Patt et al, 1997; Wanner et al, 2006). Medicinal uses Anethum is used as an ingredient in gripe water, given to relieve colic pain in babies and flatulence in young children (Pulliah, 2002). The seed is aromatic, carminative, mildly diuretic, galactogogue, stimulant and stomachic (Hornok, 1992; Sharma 2004). The essential oil in the seed relieves intestinal spasms and griping, helping to settle colic (Duke, 2001; Fleming, 2000). The carminative volatile oil improves appetite, relieves gas and aids digestion. Chewing the seeds improves bad breath. Anethum stimulates milk flow in lactating mothers, and is often given to cattles for this reason. It also eases urinary complaints, piles and mental disorders (Nair and Chanda, 2007). 18 IJPHA Vol. 1 Issue 4 Spring 2013 Other applications and importance Anethum seeds are used as a spice, and its fresh and dried leaves called dill weed are used as a condiment and tea. The aromatic herb is commonly used for flavoring and seasoning of various foods such as pickles, salads, sauces and soups (Blank and Grosch, 1991; Huopalathi and Linko, 1983). Fresh or dried leaves are used for boiled or fried meats and fish, in sandwiches and in fish sauces. It is also an essential ingredient of sour vinegar. Dill oil is extracted from seeds, leaves and stems, and is a pale yellow color, darkens with age, with the odor of the fruit and a hot, acrid taste. The essential oil used as a flavoring in the food industry. It is used in perfumery to aromatize detergents and soaps and as a substitute for caraway oil (Lawless, 1995). Anethum is used as a preservative as it inhibits the growth of several bacteria like Staphylococcus, Streptococcus, Escherichia coli and Pseudomonas. Compounds of dill, when added to insecticides, have increased the effectiveness of insecticides. Essential oil of A. graveolens L. is used as a repellent that is toxic to growing larvae and adults of Tribolium castaneum, a wheat flour insect pest (Chaubey, 2007). In doses of 60 minims, Anethole is a fairly potent vermicide for hookworm (Kirtikar et al, 1987). Pharmacology Several experimental investigations have been undertaken in diverse in vitro and in vivo models. Some pharmacological effects of Anethum graveolens have been reported such as antimicrobial (Nair and Chanda, 2007; Chaurasia and Jain, 1978; Delaquis et al, 2002), antihyperlipidemic and antihypercholesterolemic (Yazdanparast and Alavi, 2001). Seed extracts of A. graveolens L. have significant mucosal protective, antisecretory and anti-ulcer activities against HCl- and ethanol-induced stomach lesions in mice (Hosseinzadeh et al, 2002). Two flavonoids, quercetin and isoharmentin, have been isolated from A. graveolens L. seed and shown to have antioxidant activity that could counteract free radicals. This effect may help to prevent peptic ulcer (Mahran et al, 1992; Mohele et al, 1985). Dill fruit hydrochloric extract is a potent relaxant of contractions induced by a variety of spasmogens in rat ileum, so it supports the use of dill fruit in traditional medicine for gastrointestinal disorders (NaseriGharib and Heidari, 2007). Crude extracts of A. graveolens L. besides having strong antihyperlipidemic effects can also improve biological antioxidant status by reducing lipid peroxidation in the liver and modulating the activities of antioxidant enzymes in rats fed a high fat diet (Yazdanparast and Bahramikia, 2007). It has been reported that aqueous extracts of A. graveolens showed a broad-spectrum antibacterial activity against S. aureus, E. coli, P. aeruginosa, S. typhimurium, Shigella flexneri and Salmonella typhii (Arora and Kaur, 2007). The higher activity of the extracts can be explained by the chemical structure of their major constituents, such as dillapiole and anethole, which have aromatic nuclei containing polar functional groups that are known to form hydrogen bonds with active sites of the target enzyme (Farag et al, 1989). Metabolites of importance Various different compounds have been isolated from the seeds, leaves and inflorescence of this plant; 17 volatile compounds have been identified. The main constituents of dill oil are a mixture of a paraffin hydrocarbon and 40 to 60% of d-carvone (23.1%) with d-limonene (45%). It also consists of α-phellandrene, eugenol, anethole, flavonoids, coumarins, triterpenes, phenolic acids and umbelliferones. The fruit yields about 3.5% of the oil; its specific gravity varies between 0.895 and 0.915. Molecules of interest: Carvone and Limonene Carvone and limonene are monoterpenes which are present as main constituents of dill oil from fruits (Santos et al, 2002). α-phellandrene, dill ether and myristicin are the compounds which form the important odor of dill herb (Blank and Grosch, 1991; Bonnlander and Winterhalter, 2000). Monoterpenes are 10-carbon members of the isoprenoid family of natural products; they are widespread in the plant kingdom and are often responsible for the characteristic odors of plants. These substances are believed to function principally in ecological roles, serving as herbivore-feeding deterrents, antifungal defenses and attractants for pollinators (Bouwmeester et al, 1998). Seventeen compounds have been identified in Indian dill leaf (Raghvan et al, 1994). The applications of carvone are as fragrance and flavor, potato sprouting inhibitor (Score et al, 1997), antimicrobial agent and building block in a biochemical environment. D-limonene is one of the most common terpenes in nature. It is a major constituent in several citrus oils (orange, lemon). Being an excellent solvent of cholesterol, d-limonene has been used clinically to dissolve cholesterolcontaining gallstones. It has chemo-preventive and chemo-therapeutic activities and is also reported to have low toxicity in pre-clinical studies (Vigushin et al, 1998). Myristicin is a naturally occurring insecticide and an important compound of the essential oil (Duke, 2001; Dhalwal et al, 2008). Anethole is a terpenoid that is present in minor quantity in Anethum, but is also found in the essential oils of anise and fennel (Newberne et al, 1999). It is used as a flavoring substance. p-anisaldehyde has a strong aroma and is an important component in pharmaceuticals and perfumery. 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Nutritional value of floral nectar sources for flight in the parasitoid wasp, Cotesia glomerata. Physiol Entomol. 31 (2), p127–33. Warrier P K, Nambiar V P K, Ramakutty C. (1994). Arya Vaidya Sala. Vol. 1. Kottakkal Madras, India: Orient Longman Limited. p153–4. Yazdanparast R and Alavi M. (2001). Antihyperlipidaemic and antihypercholesterolaemic effects of Anethum graveolens leaves after the removal of furocoumarins. Cytobios. 105 (410), p185–91. Yazdanparast R and Bahramikia S. (2007). Improvement of liver antioxidant status in hypercholesterolamic rats treated with A. graveolens extracts. Pharmacologyonline. 3, p88–94. Editor's note This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. This article was not reprinted in its entirety. For the full article: Pharmacogn Rev. 2010 Jul-Dec; 4(8): 179–184. doi: 10.4103/0973-7847.70915 Gyan Singh Shekhawat PhD. Area of study: Plant Tissue Culture & Plant Biochemistry. Associate professor at the Department of Bioscience and Biotechnology, Banasthali University, Banasthali, Rajasthan, India. Sayantan Jana PhD. Department of Physiology, Drug Development Diagnostics & Biotechnology Division, CSIRIndian Institute of Chemical Biology, 4 Raja S.C. Mullick Road, Jadavpur, Kolkata 700032, India. East Meets West: An Integrated Viewpoint of The Skin as an Avenue of Absorption and Healing in Aromatherapy Terese Miller, DOM, CA Image © Dianna Meir For Aromatherapists, the skin represents a vast canvas waiting to be painted with our palettes of essential oil-rich lotions, sprays, and butters. Our design is to color the surface of the body with scent and healing moisture. On a deeper level we regard the skin as a major route of absorption, a passageway into the body’s vital systems. Here we send our formulas to act and counteract the forces of dis-ease and discomfort. In medical terminology skin is defined as cutaneous tissue comprised of the epidermal and dermal layers. The skin actually has five layers over most of the body and six on the palms of the hands and feet. The epidermis consists of four layers of skin cells in different stages of life. The outer most layers of cells are dead and sloughing off the surface. The remaining layers are busy birthing new skin cells and making a tough cementing protein called keratin. Western Science and Chinese Medicine, while holding different perspectives, offer valuable insights into the skin and its related structures. This article will present both the solid evidence of the West and the more energetically based beliefs of the Eastern mind. In Western Medicine the skin is officially part of the Integumentary system. It is considered the largest organ in the body. In Chinese Medicine the skin is an extension of the Lung (yin). Coupled with the Large Intestine (yang), the skin falls within the auspices of the element of Metal. Metal is one of the five energetic elements that rule the body of man and the natural world. Integumentary system The skin along with the hair, oil glands and nails comprise the vast Integumentary System. The skin serves as a protective waterproof covering for the entire body allowing for the excretion of wastes and helping to regulate body temperature through the functioning of the pores. It contains sensory nerve receptor sites that detect sensations such as pressure, temperature, and pain. With significant exposure to sunlight it provides a vehicle for vitamin D synthesis. The skin also acts as a first defense against infection and dehydration (Martini and Bartholomew, 2009). Diagram of the skin dreamstime.com © Anton Novik The dermis lies just below the protection of the epidermis. Here we find a plentitude of blood vessels, nerve fibers, hair follicles, and sweat glands. It is the dermal layer that provides the higher function of the Integumentary System allowing absorption and elimination in fluid respiration. Collagen and elastin are two very important components of the dermis. Collagen is a protein that gives us surface shape and contour while elastin acts as a pliable glue holding the skin in place while stretching and rebounding through constant movement. The collagen and elastin fibers are interlaced like the warp and woof of a resilient fabric. IJPHA Vol. 1 Issue 4 Spring 2013 21 The lung-large intestine organs of the metal element For many readers this first encounter with Traditional Chinese Medical nomenclature will require a bit of patience and imagination. These concepts are foreign to our Western sensibility, as mysterious as the ancient culture that envisioned them 23 centuries before our reading. disease is cured" (Moyers, 1993). In Chinese Medical theory we come upon a very different discussion about the importance of skin and its function. Here the skin represents the entire body surface including sweat glands, pores, and hair, which act as a barrier against the invasion of exogenous pathogenic factors. The skin does not really exist as a separate system. It is always seen within its mutually influencing relationship to the lung. Through the dispersing function of the lung, the essentials of food and water are transported to the body surface in order to nourish the skin, hair, and muscles. The Yin/Yang paired meridian and organ relationship for Metal consists of the Lung and Large Intestine. The classical functions of this pair of organs include governing the skin and exterior of the body. Their meridians open to the nose and throat. Metal controls Qi and the downward flow of body fluids. “The lung also mists defensive (Wei Qi) out to the body's surface and regulates the opening and closing of the pores" (Unschuld and Tessenow, 2011). The lung has the ability to protect the organic body by controlling the quality and function of the skin to defend against the invasion of exogenous pathogenic factors. Unchecked, this “evil wind” would proceed to enter through the skin and hair to the lung carrying a damaging amount of cold or heat. Protective Qi pushes out to prevent pathogenic qi from pushing inward. The organic body is easily attacked by external pathogenic factors. In other words, the "evil wind" could be a chilling draft, a breezy Spring day where one encounters allergens, or the sneezing and coughing of a febrile work associate. If the lung is strong it can easily defend the surface by opening the pores and maintaining the barrier of protective Qi. Stimulation of appropriate meridian points will vitalize that function. "This is truly something special to Chinese medicine. The meridian is considered to connect the interior and the exterior of the body. Thus, our inner diseases can be treated through the exterior of the body. Once the Qi of the meridian is opened up, the 22 IJPHA Vol. 1 Issue 4 Spring 2013 In Taoist principals of The Theory Of The Five Elements, the Lung is associated with the Metal Phase. Metal is Autumn, the West, the color white, pungent tastes, dry climates, harvest, sadness, crying, righteousness, and the ability to create order. Absorption Let us look at what we know in the West to be true of the skin regarding absorption of Essential Oils (EOs). To penetrate the many layers of the epidermis and dermis, molecules need to be relatively small, mostly lipophilic, but with some hydrophilicity. Most EO constituents conform to this description. Absorption occurs at different rates depending on the size of the molecules and their lipo/hydrophilicity. Aromatherapy products often include a fatty substance. Many of these have their own desirable properties that enhance the intention of a blend, and they have very variable skin absorptions. While it can be generally stated that fatty oils tend to retard EO absorption, transcutaneous absorption of some fatty acids occurs over time, and some EO constituents aid in this process. Those EO constituents that cross the epidermis travel inward to the depth of the capillary beds where they are taken into the blood. Rate of absorption can be enhanced by massage or applied warmth (e.g. infrared). Hydration increases skin permeability as demonstrated in the use of essential oils in a bath. Occlusion, or covering the skin, adds both warmth and decreases surface evaporation (Price and Price, 2012). Stepping once again into the Taoist model, absorption must be seen in terms of Qi transmutation and transportation. The material becomes the ethereal. The skin as an extension of the Lung respires along with the physical lungs themselves. Air, or in this instance the “vapor” of the Essential Oils, is respired into the body and transformed into Qi going deep into the waterways through the descending action of these Metal organs. Actions As Aromatherapists we routinely use skin application of blends to assist in resolving conditions in body systems. For example: A belly blend to calm an irritable bowel or resolve constipation A chest rub to decongest and expectorate phlegm and resolve viral, bacterial, and fungal agents associated with the infection A massage blend to stimulate lymphatic movement and act as a diuretic for sluggish, swollen legs and feet An anti-inflammatory, antispasmodic, and analgesic blend for injury and chronic pain issues Blends to heal conditions of the skin itself like acne, eczema, burns, and abrasions There are many forms and levels of Qi in the body. Just as the Spleen energetic assists the Stomach by transforming the food we eat into Gu Qi (the essence of grain), the Large Intestine assists the Lung in its transformation of Da Qi (the essence of air). The Gu and Da Qi combine to create Zhong Qi (gathering Qi of the chest). The gathering Qi is more subtle and refined and therefore dynamically usable by the body. It flows downward to meet and collect the Original Qi of the Kidneys and forms the “Sea of Qi” in the chest. The further we go into this lineage of deeper and broader levels and functions of Qi, the more one can begin to fathom the inter-connectedness of energy in and around the body. By treating any one part the whole is transformed. Aspects of enhancing absorption here are governed less by external stimulation than emotions. If the client is feeling supported and optimistic then their field will be receptive to what is given. Feelings of depression, grief, sadness, or anxiety are emotional dissemblers of balance within the Metal element. If these emotions are present, the disharmony within the Lung will diminish its ability to function optimally (Maciocia, 1989). We may choose our Essential Oils by chemical constituents that research shows to provide certain actions. We may base our decisions on experience, instinct, and timeworn traditional beliefs. We use carriers and other EOs that we know to be skin nourishing to protect our route into the body. We are always aware of the emotional components available to us in the oils that so often do double duty in our blends, supporting the body, the mind, and the spirit simultaneously. Using an Eastern approach, the Essential Oils can be similarly concocted in blends although allowing the energetic model to bear fruit encourages a shift in thought and application. Just as Acupuncture points are chosen and stimulated with needles and moxabustion, EOs can be chosen for their energetic qualities and pressed into Acupuncture points. This model of treatment can be as complex or as simple as you desire. If you follow the Tao, keep it simple. Image of metal yin yang symbol Istock.com © Blackbeck IJPHA Vol. 1 Issue 4 Spring 2013 23 As an Aromatherapist there is a technique that you can employ today that utilizes the principals discussed. You can apply EOs manually to the Shu Points on the back of the torso. The Shu points run paraspinally and have powerful associations to all of the organs and their elements. By applying Shu points Photo © Redwing Press a thin layer of carrier oil down the paraspinal muscles you can get a tactile sense of where the tissue feels stuck. You have a carrier on the skin and so you can apply one drop of Essential Oil to the Shu points safely. Taoism regards living authentically in the moment as a core principal of life and certainly working with Qi is a practice that can only exist in the absolute present. Armed with your knowledge and the inner wisdom you already possess about your client and the oils, apply your chosen oil(s) to the Shu point(s), pushing it into the skin with the Qi and intention at your fingertip. Allow a sense that the Qi present at the tip of your finger is a combination of your skill, true intention, and the “fire in your belly.” Breathe deeply from the belly, gathering the Original Qi and let it rise to your heart to collect your true intention. Now the Tao is flowing from your heart down your arms and finally out the tips of your fingers. Envision the energy of the oil being accepted and carried deep into the inner cosmos of your clients’ energy body. Entrain your breath to that of your client and hold that space until you feel a sense of completion. Moving, rectifying, and disinhibiting are common words translated from Chinese characters that describe the actions needed to promote the optimal flow of Qi and Blood. These activities support balance between the body, mind, and spirit. This need for balance is ongoing. Just as a plant stretches to the warmth and vitality of 24 IJPHA Vol. 1 Issue 4 Spring 2013 the sun, our human form uses all the resources made available to thrive. The work you do in this way will set the wheels of change in motion, reaching deep into the energetic field and echoing that change outward through the many layers we inhabit to the surface we manifest. The practice of Aromatherapy is rapidly gaining credibility driven by the richness of clinical research that is increasingly available. Likewise, recognition of the validity of Eastern practices focused on life force (Qi) has been growing in our culture. Both of these resources are limitless. By integrating Eastern and Western models of treatment, we can take two lines of thought and create a circle of holistic healing. References Jäger W, Buchbauer G, Jirovetz L, Fritzer M. (1992). Percutaneous absorption of lavender oil from a massage oil. Journal of Cosmetological Chemistry. 43 (January-February), p49-54. Maciocia G. (1989). The Functions Of The Lungs. In: The Foundations Of Chinese Medicine. 4th ed. London: Churchill Livingstone. p83-87. Martini F and Bartholomew F. (2009). Essentials of Anatomy and Physiology. 5th ed. New York: Benjamin Cummings. Moyers B. (1993). The Mystery of Chi. In: Healing and The Mind. New York: Doubleday. p257-314. Price S and Price L. (2012). Aromatherapy For Health Professionals. 4th ed. London: Churchill Livingstone. p128-136. Unshuld P and Tessenow H. (2011). Huang Di nei jing su wen, An Annotated Translation of Huang Di's Inner Classic-Basic Questions. Los Angeles: University of California Press. Chapters 1-52. Terese Marie Miller, Doctor of Oriental Medicine and Certified Aromatherapist, has promoted wellness in her private practice for 25 years. She is co-owner of Essential Elements; Aromatherapy For Healthy Living offering GC/ MS tested essential oils and Aromatherapy product design. As co-founder of Essential Elements School Of Aromatic Studies, Terese teaches a NAHA approved 235 hour Aromatherapy Certification Program along with other curriculum. In 2011-12 she served as Florida State Representative for AIA. Web: EssentialElementsSite.com Contact her at [email protected] Plant sprouts reaching for the sun dreamstime.com © Alena Brozova Case Study: Using Essential Oils for the Management of Haemorrhoids Sharon Falsetto, Clinical Aromatherapist iStock.com © Jana Blašková Haemorrhoids are a painful condition that can cause distress and discomfort to the sufferer. If left untreated, haemorrhoids can develop into a more complex issue which, in extreme cases, may result in treatment with sclerotherapy or cryosurgery. However, mild cases of haemorrhoids can be controlled by a combination of diet, regular toilet habits, and essential oils to control some of the more painful and irritating symptoms. Overview of haemorrhoids Haemorrhoids develop on the veins in the lining of the anus and the junction of the rectum due to sustained pressure; sustained pressure can be the result of chronic constipation and straining repeatedly to pass hard faeces. Haemorrhoids are also a common condition associated with pregnancy and recent childbirth when pressure has been increased for a period of time in the pelvic region. Some people are prone to haemorrhoids during periods of stress due to the associated constipation issues triggered by the stressful situation. maintaining regular toilet habits can help keep the symptoms at bay once the initial problem has been addressed. More serious cases of haemorrhoids may need to be treated with methods such as sclerotherapy, cryosurgery or even a haemorrhoidectomy in which the haemorrhoids are surgically removed. In such cases, professional medical advice should be sought. Case study Client history The client is a healthy woman in her 40s with a balanced diet of fruit, vegetables, and meat. She had no major health issues but had been going through a period of stress in her life. As a consequence of this stress and the pattern in her health history during previous bouts of stress, constipation became a problem. This resulted in the formation of haemorrhoids. She was familiar with the use of essential oils in aromatherapy practice and sought help with relief from the itching and pain of her haemorrhoids. Haemorrhoids restrict the normal circulation of blood to the rectum. They can result in rectal bleeding and discomfort when passing faeces. If the haemorrhoids are prolapsed itching, redness and a mucous discharge around the anus may develop too. Prolapsed haemorrhoids may lead to thrombosis which causes extreme pain for the patient. Another complication of haemorrhoids is the development of anemia as a result of blood loss caused by rectal bleeding. The aim of the treatment of haemorrhoids is to reduce symptoms such as swelling, pain, and itching. A high fiber diet, drinking plenty of fluids, and . Flickr.com © Jacky Smith IJPHA Vol. 1 Issue 4 Spring 2013 25 Aromatic treatment In January 2012, a selection of essential oils were blended together in an unscented white lotion base to be applied externally to the affected area of the anus. The rationale for choosing the specific essential oils was as follows: Cypress (Cupressus sempervirens) – high in monoterpenes such as pinene, camphene and limonene, noted for stimulating and phlebotonic properties (Price and Price, 2002; Caddy, 1997); Cypress is recommended by several sources as proving effective for the relief of the symptoms associated with haemorrhoids (Caddy, 1997; Davis, 1999). Frankincense (Boswellia carteri)* – high in monoterpenes such as pinene, thujene and limonene; noted for anti-inflammatory and analgesic properties (Price and Price, 2002). Juniper (Juniperus communis) – high in monoterpenes such as pinene and limonene; noted for analgesic and antiseptic properties (Caddy, 1997; Price, 2000). An unscented white lotion base was chosen for the area of application as it was easy to administer, gentle to use and wasn't slippery like an oil base. Observations and outcome By day four, improvements were noted in the swelling and pain surrounding the area of the haemorrhoids. Although daily bowel movements had still not commenced, the itching had reduced. After several more days and several bowel movements, the pain surrounding the area had reduced significantly. By the end of week two, normal bowel movements were in place once again and the haemorrhoids appearance and size were reduced. Evaluation During the period of application of the essential oil blend, the client obtained relief from the itching and pain caused by the haemorrhoids. Due to the site of the problem, the blend was initially difficult and uncomfortable to administer. The application was easier as time progressed and the pain and inflammation were reduced. References British Medical Association. (2002). Illustrated Medical Dictionary. UK: Dorling Kindersley. Caddy R. (1997). Aromatherapy: Essential Oils in Colour. Caddy Classic Profiles. UK: Amberwood Publishing Ltd. Davis P. (1999). Aromatherapy: An A-Z. UK: Vermilion. Price S. (2000). Aromatherapy Workbook. UK: Thorsons. Formula 2 oz (60ml) unscented white lotion base 4 drops Cypress (Cupressus sempervirens) 6 drops Frankincense (Boswellia carteri) 8 drops Juniper (Juniperus communis) The blend was applied twice daily, once in the morning (after going to the toilet) and once at night prior to going to bed. Client was reminded to wash hands each time the blend was applied. To avoid bacterial contamination, it was recommended that unwashed hand(s) not be dipped into the lotion. The blend was used for 10 days. It is also important to note that this blend was for the external application onto the haemorrhoids located outside the anus. 26 IJPHA Vol. 1 Issue 4 Spring 2013 Price S and Price L. (2002). Aromatherapy for Health Professionals. UK: Churchill Livingstone. Waugh A and Grant A. (2001). Ross and Wilson Anatomy and Physiology in Health and Illness. UK: Churchill Livingstone. *Boswellia carteri is considered to be an endangered plant species. You can use Boswellia serrata as a substitute because it is a faster growing, larger tree than Boswellia carteri. Sharon Falsetto is a UK certified clinical aromatherapy practitioner with an online aromatherapy business located in Arizona, United States. She custom blends essential oils for individual clients, spas, and therapists for both clinical and scent purposes. Sharon also tutors aromatherapy courses and has written e-books specifically for the aromatherapy beginner. Sharon is a professional writer, with articles published both on- and off-line. Website: www.sedonaaromatherapie.com Email: [email protected] Let the Sun Shine In: A Psychospiritual Profile of Popular Citrus Essential Oils Katharine Koeppen, RA, LMT, NCTMB Crude oils derived from citrus fruits are among the most loved and most used by aromatherapists, whether beginner or expert. Many of us can recite their uses for physical ailments by rote, but when it comes to emotional and spiritual applications these oils begin to blend together. All seem to be useful for anxiety and depression, and all seem to be uplifting. This is not surprising because citrus oils have more commonalities than differences. This article will discuss key common psychospiritual properties of the most frequently used citrus oils, and further expound on this family by delineating the subtle differences among them. Essential oils which are composed almost entirely of monoterpene hydrocarbons, be they citruses, conifers or the like, largely have to do with some form of cleansing or purification. In the case of citrus oils, this purification occurs by physically freeing up blood and lymphatic circulation, and by purging toxins via high levels of antimicrobial activity. However, this cleansing property also extends to emotional and spiritual levels. Citruses are simple and strongly nurturing, feeding our souls equally as their fruits feed our bodies. They allow us to honor and enjoy the sweetness of life. From an energetic standpoint, all citrus oils support the solar plexus chakra and a few of them have an affinity for multiple chakras. The solar plexus chakra is our center of self-esteem, self-confidence, responsibility, personal protection, and the source of our personal power in terms of how we as individuals relate to groups. This chakra also manages the often complex relationship with our chosen profession, life’s work, or legacy. Orange, Lemon, Grapefruit and Mandarin all reflect the very colour of this energy Citrus fruits © Holistic Photo center, variously described as bright yellow or brilliant yellow-orange. All citrus fruits share a common ancestor, Mandarin (Citrus reticulata). This forebearer fruit originated in the vicinity of southern China and Southeast Asia where it was heavily documented in medicinal use and regarded as a symbol of good luck and prosperity. Mandarin was brought to the Mediterranean centuries ago by Arab and Persian traders, and careful cultivation by Arab gardeners produced several distinct crosses and hybrids. By the Middle Ages, North African peoples had introduced oranges, mandarins, lemons, and citron to Spain and Sicily, and by the Renaissance these and several additional species were cultivated throughout the Mediterranean basin. Bitter orange is thought to have been the original “golden fruit” grown by a miraculous tree in the mythical Garden of Hesperides. The tree was gifted to Hera by the great mother Gaia upon Hera’s marriage to Zeus. As a gift, this magical tree was prized, symbolizing the union of earth and sky, spirit and matter. Its precious fruit was reflective of the alchemical aur, or gold, believed to be sunlight condensed into earthbound matter. All citruses share this solar property making them an energetic bridge between body and soul. Sweet orange, the Zest for Life Pharmacist and aromatherapy pioneer Paolo Rovesti cited Sweet Orange (Citrus sinensis) oil as an Oranges effective antidepressant, and the peel © Holistic Photo was used to treat melancholia in Europe for at least three centuries prior to Rovesti’s findings. Sunny and cheerful, Sweet Orange seems IJPHA Vol. 1 Issue 4 Spring 2013 27 the essential oil of the eternal optimist. Its bright hue is the colour of joy and it can be used to alleviate stress, anxiety, tension, irritability, and frustration. The Sweet Orange characterology is that of a young person: one who is eager, loves challenges, is excited about his work, and wants to have it all, ideally as soon as possible. In many respects, he resembles the archetype of the Fool, a sensitive innocent who has yet to emotionally mature but who has set out very independently on a grand adventure. In his inexperienced youth, the Sweet Orange person wants to create and maintain his identity but doesn’t know how to handle power inside or outside the workplace, and doesn’t understand the concept of sharing. He doesn’t yet have a framework on how to properly relate to others because he has yet to achieve the wisdom of experience, and this gets him into trouble. Like the Fool, he can be charming and goodnatured one moment, cranky and petulant the next. A person who resonates with Sweet Orange can be a youthful Type A in the making. He often throws himself into his work, where he develops perfectionist tendencies, intolerance of mistakes and a tendency to judge. Consequently, he is prone to health issues related to overwork and rigidity such as headaches, eyestrain, irritable bowel syndrome (IBS), nervous indigestion, extreme anxiety, and poor appetite. When out of balance, he is given to nervous fidgeting, impatience, snappishness, bouts of aggression, loss of spontaneity, tossing about during sleep, and feelings of helplessness (which he abhors). His overactivity puts a strain on the sympathetic nervous system (SNS) and he begins to burn out. This constitution can work productively in short bursts but has no stamina, so prolonged heavy activities result in asthenia and depression. When in this state, a Sweet Orange type loses his enthusiasm and starts to expect obstructions and difficulties at every turn. Wherever he looks, he sees Murphy’s Law. Incorporating Sweet Orange oil into such a person’s treatment regimen will bring back a sense of ease and alleviate frustration, as well as the exhaustion and boredom of burnout. Citrus sinensis gently tonifies the SNS without overstimulating the nervous system. When in balance, the natural, sunny optimism of this archetype returns. His big heart and giving spirit come back into play, he becomes less thin-skinned, and obstacles disappear. His will to 28 IJPHA Vol. 1 Issue 4 Spring 2013 succeed strengthens and, most importantly, he is able to take a more mature view toward his life’s work by getting back in touch with the joy it brings him. A somewhat wiser Fool is ready for his next adventure. Lemon, the Purifier Lemon (Citrus limonum) was Lemons parented by the original citrus © Holistic Photo (Mandarin) and Citron (Citrus medica). Known to Mesopotamian peoples as the Median apple, Lemon symbolized both the fruitfulness of the mother goddess and bittersweet quality of life. In old Europe it was used primarily as an insect repellant, but by the late Renaissance it was regarded as a blood cleanser and cure for any type of virulent toxin. Today, Lemon odor has strong associations with cleanliness and has even been used to initiate cleaning behaviour in scientific studies. Lemon is a premier liver detoxifier, and in Traditional Chinese Medicine (TCM) this organ is associated with the emotion of anger. TCM holds that the liver controls the blood (upon which the life force travels), and Western medicine recognizes that this fluid-rich organ stimulates the blood and produces lemon-coloured bile. Accordingly, the Lemon characterology is that of one who tends toward a sour disposition, frustration, has issues of fluid imbalance, and is prone to the mental fogginess that results from liver stagnation. Like the Sweet Orange archetype, the imbalanced Lemon archetype has a tendency to become bogged down, but her sluggishness is both physical and emotional. Emotions travel upon the fluid body, and stagnant blood and lymph collect both metabolic waste and muddied feelings. Consequently, the individual who resonates with Lemon is often confused, listless, unfocused, has a short attention span, and overthinks but never comes to any logical conclusions. When mired in a toxic liquid stew, her immune system suffers and she is prone to developing opportunistic illnesses and flare-ups of latent infections such as herpes. As her condition deteriorates she falls into worry and depression, struggles over simple decisions, develops irrational fears, and can segue into chronic physical illness. Spiritually, her natural inclination is to seek a deep connection with a Higher Power, but she loses this vital link in her disharmonious state and may resort to substance abuse or become an information junkie in order to fill the void. Lemon also cleanses and supports the spleen and pancreas which are, respectively, key to immune system function, blood health, and proper dietary assimilation. In TCM, the spleen/pancreas is considered one organ and associated with issues of selfesteem, control, and security. Consequently, a Lemon constitution likes things fairly controlled and feels most comfortable with tight regimens regarding things such as exercise, diet, housekeeping, and work hours. This individual is highly grounded and enjoys material comforts when in balance. When out of balance, she becomes overly concerned with the temporal world and focuses on material acquisition, excessive monitoring of possessions and investments, and is mistrustful of anyone who questions her behaviour. Her primary focus is that of attachment and this can manifest in worry, food cravings, weight gain, bloating, gallstones, kidney stones, varicosities, and a guarded posture. Lemon oil provides both a physical and emotional purging, purifying her body, breaking her attachments, enlivening her senses and enabling rational thought. Archetypally, Lemon is the Tightrope Walker whose impeccably controlled high wire act requires a crystal clear mind and a perfectly tuned body. Bergamot, the Lightbringer Multiple legends exist regarding the murky origins of Bergamot (Citrus Bergamot bergamia), but recent DNA analysis istock.com © slallison has solved the mystery: Bergamot is a cross of Citron and Bitter Orange. This somewhat rare fruit has narrow geographic distribution because it is notoriously difficult to grow; the trees are highly prone to fungal infection. For centuries, Reggio Calabria has been home to the world’s most extensive cultivation of Bergamot, and home to the stereotypical Mad Italian; among Calabrians there is a strong folkloric history of depression and mood swings. The essential oil was a favorite of Paolo Rovesti, who used it successfully in psychiatric research on anxiety and depression. The negative aspect of Bergamot takes many of the characteristics of his Orange parent and magnifies them. A Bergamot individual is the least mentally stable of the citrus temperaments. He falls into depression easily, burns out rapidly, and may suffer bouts of agitation and hyperactivity. Creative, hypersensitive, and impressionable, he often feels the need to escape from outside stimulation through fantasy, alcohol, or drug use. Left unchecked, this can lead to paranoia and distrust of everyone and everything around him. Bergamot is very critical of himself and others, lacks compassion, and with his addictive tendencies, becomes imprisoned in a joyless personal hell. Many of this temperament’s imbalances stem from a sympathetic nervous system that has lost the ability to turn off. Bergamot is predisposed to illnesses typical of nervous system overload such as eczema, nervous acne, stress incontinence, IBS, panic attacks, and chronic insomnia. In the absence of sunlight, which he adores, he can develop seasonal affective disorder (SAD). The essential oil is a wonderful balancer of the SNS, and a happy Bergamot individual is filled with brilliant, concentrated light. His emotional resilience and stability return. He has unbridled access to his creative talent and intuitive abilities. The oil is also a great opener of the heart chakra, allowing him to regain compassion and courage, enabling forgiveness of self and others. Such qualities are necessary to deal with the frequent and deep explorations of the dark side which so fascinate this temperament. Psychospiritually, Bergamot is the archetypal lone Candle in the Dark, the light at the end of the tunnel. The oil carries precious light to the deepest, darkest parts of soul. There, it sputters and sparks into a Roman candle, flaring heavenward and uniting with Divine Light. IJPHA Vol. 1 Issue 4 Spring 2013 29 Grapefruit, the Essence of Hope Zesty Grapefruit (Citrus paradisii) is the offspring of a Sweet Orange father and a Pomelo (Citrus Grapefruit maxima) mother. Originating in flickr.com © geekspeakllc the Caribbean, it was once known as the “forbidden fruit” of Barbados. The heavy, juicy citrus has long been a mainstay of dieters. Its essential oil has a pronounced affinity for the lymphatic system and detoxifies multiple organs: liver, gall bladder, spleen, and pancreas. The ability to flush and restore normal fluid flow to these organs is important to the Grapefruit individual, who tends toward a phlegmatic constitution. She has difficulty setting appropriate boundaries and is often burdened by the problems of others. Chronic self-esteem issues are the hallmark of the Grapefruit person, resulting from too much responsibility and not enough positive reinforcement during childhood. She has very high expectations of herself and wallows in worry and selfcriticism when she can’t meet them. Grapefruit is exquisitely sensitive, even more so than her other citrus cousins. Like Orange, Bergamot and Lemon, she has problems with depression and anxiety, but hers are caused by being overly compassionate and dutiful. She fears letting others down and often gets into situations where she feels hopelessly trapped. She has the digestive problems typical of a citrus, with a greater tendency for weight gain and lymphatic sluggishness, plus a propensity for food addiction, stress eating, and other eating disorders. Food and sleep are her safety valves. When out of sorts, disappointment hangs over her like a cloud and she numbly retreats into bed with a box of bonbons, pulling up the covers and shutting out desperation and exhaustion. Grapefruit is a person of unquestionable integrity and deep spirituality. She is an evolved citrus and understands the need to self-actualize, but is distracted from her spiritual path by her need to attend to others. She frequently becomes enmeshed in toxic relationships. A natural empath, she has a direct line to spiritual guidance which becomes blocked when emotional and physical stasis interfere. 30 IJPHA Vol. 1 Issue 4 Spring 2013 A key emotion for Grapefruit is hope. In tarot this is personified by the Star which features a kneeling woman pouring a vessel of water into a crystalline pond, presided over by a tranquil night sky. The Star signifies the hope that returns with emotional clarity after a period of heaviness. All is now purified, flowing in perfect harmony, and the right path is clear. With renewed hope, Grapefruit reclaims her power and achieves inner peace. The Happy Family There are many other members of the citrus family that yield beneficial essential oils: Mandarin (Citrus reticulata Blanco var. Mandarin; Citrus deliciosa Tenore), Tangerine (Citrus reticulata Blanco), Lime (Citrus aurantifolia), Citron, Yuzu (Citrus junos) and Combava/Kaffir Lime (Citrus hystrix). Each of these oils has its own special ability to banish the blues and uncover the optimist in all of us. Together they truly constitute a happy family. Whether bitter or sweet, citruses collectively cleanse us and joyfully lift our bodies, minds, and souls to the light. Author’s note: Although citrus oils are primarily neutral in terms of male/female characteristics, they are given gender specific pronouns for narrative purposes. References American Society for Horticultural Science. “Genetic Origin of Cultivated Citrus Determined: Researchers Find Evidence of Origins of Orange, Lime, Lemon, Grapefruit, Other Citrus Species.” ScienceDaily. (2011, January 26). http://www.sciencedaily.com-/ releases/2011/01/110118101600.htm Last accessed 8 January 2013. Berkowsky B. (2000). Essential Oils and the Cancer Miasm. Mount Vernon, Washington: Joseph Ben Hil-Myer Research, Inc. Berkowsky B. (2000). Spiritual Phytoessencing Diploma Course Workbook. Vol. 1, 5. Mount Vernon, Washington: Joseph Ben Hil-Myer Research, Inc. Holland R, Hendriks M, Aarts H. (2005). Smells Like Clean Spirit. Psychological Science. 16(9), p689-693. EBSCOhost Academic Search Premier database. Last accessed 11 September 2008. Mojay G. (1997). Aromatherapy for Healing the Spirit. Rochester, Vermont: Healing Arts Press. Paolo Rovesti Biography. Paolo Rovesti Institute. http:// www.istitutorovesti.it/en/paolo.php. Last accessed 8 January 2013. Pollack R. (1997). Seventy-eight Degrees of Wisdom. London: Thorsons. Katharine Koeppen is a registered clinical aromatherapist in private practice. She is the founder of Aromaceuticals, a company providing high integrity essential oils and aromatherapy products for complementary and integrative healthcare. A writer and educator, she maintains the AromaBlog at www.aromaceuticals.com. Cancer-Preventing Properties of Essential Oil Monoterpenes d-Limonene and Perillyl Alcohol Mark Brudnak, PhD, ND Figure 1 Structures of Perillyl Alcohol and Limonene This article originally appeared in Positive Health Issue 53 - June 2000 and was revised by the author for the IJPHA in February 2013. Monoterpenes (MTs) are widely found in common citrus fruits such as oranges. While MTs are used as cleaning agents (try placing a small amount on the front hubcaps of your car to clean off the black grime) due to their solvent properties, they are far from being poisons. Indeed, nothing could be further from the truth for these wonderful, naturally occurring, and health-promoting substances. While the solvent properties of monoterpenes have been exploited clinically to dissolve gallstones (Igimi et al, 1976), monoterpenes are also the focus of much investigation in the area of cancer prevention and therapeutics. Cancer prevention, inhibition, and regression are the most noteworthy attributes of the MTs. Dlimonene (DL) and perillyl alcohol (POH) have been shown to be chemopreventive against mammary (Crowell, 1997), liver, lung, and UV-induced skin cancer (Uedo et al, 1999), and chemotherapeutic against both experimental mammary and pancreatic tumors. DL has also been shown to inhibit angiogenesis and metastasis of human colon cancer cells (Chidambara et al, 2012). The importance of which is discussed below. Perillyl alcohol stands out as effective against human pancreatic cancer (Stark et al, 1995), against colon and liver tumors (Broitman et al, 1996), and in reduction of vein graft intimal hyperplasia (Fulton et al, 1997). Furthermore, POH is effective as chemopreventive against colon carcinogenesis, prostate, and lung cancer (Reddy et al, 1997). These are further discussed in the context of the data. What they are? As seen in Figure 1, DL is a monocyclic MT with POH, a metabolite of d-limonene, being its hydroxylated form. Monoterpenes are found in essential oils of many plants including Lemon (Citrus limon), Orange (Citrus aurantium var. sinensis per.), Grapefruit (Citrus paradisi), Caraway (Carum carvi), Dill (Anethum graveolens), Bergamot (Citrus bergamia), Peppermint (Mentha x piperita fol.), Spearmint (Mentha spicata), Citronella (Cymbopogon nardus), Lemongrass (Cymbopogon citratus) (Chanthai et al, 2012), and Tomato (Solanum lycopersicum). They are also associated with vegetables and some evergreen trees (Von Burg, 1995). POH, often distilled from lavender, is also found in cherries, mint, and celery seeds (Hohl, 1996) and can be produced synthetically. It is typically used as a flavouring agent, food additive, and fragrance and has been found to be a major volatile component of mother's milk (Von Burg, 1995). Many people regularly consume DL everyday without even knowing it. This is because DL is found in things such as orange juice, at concentrations ranging from 10-100 ppm, and chewing gum, which contains up to 2,300 ppm (Von Burg, 1995). Molecular stages of cancer formation In order to understand the mode of action of the anticancer properties of monoterpenes, it is necessary to understand a little of the molecular events that surround cancer. Normal, non-cancer cells live a limited and constrained life. Once normal cells are formed, they have a finite number of cell divisions they undergo during their life-span and, with few exceptions, they remain relatively localized to the same point in the body during this entire IJPHA Vol. 1 Issue 4 Spring 2013 31 process. As a cell lives and ages, it maintains an "awareness" of its surroundings via cell-cell communication molecules both on the cell surface and secreted. This allows the cells to determine if all around them is well and good and instructs them to maintain their relative positions in the body. Towards the end of a cell's designated life-span, certain cellular events occur which instruct the cell to terminate. This is called apoptosis or programmed cell death and is a very normal and useful event for clearing away the old and making room for the new. While it may not sound like the most compassionate thing to do to old cells, the evolutionarily derived utility of such action affords the body a mechanism to remove cells which could possibly, although rarely likely, be on their way to becoming cancer cells via mutations. longer have finite life-spans but can live indefinitely. This allows the cancer cells to escape the process of apoptosis. At this stage, the cancer cell is still relatively harmless. However, the earlier one can catch cancer, the greater the chances of success. D-limonene has been shown to induce apoptosis (Jia et al, 2012) thus restoring the body’s ability to clear damaged cells. All cells are at risk of mutation during the process of replication. A replicating cell could become a cancer threat, Mutations may eventually disrupt the cell’s growth-related regulatory machinery, leading to uncontrolled growth. These mutations can come as a result of environmental agents, toxic products of metabolism, or arise spontaneously. The exact mechanism is not important. What is important, however, is that evolution is built into the cell’s mechanisms to deal with these mutations. Apoptosis is one way to get rid of cells which have had ever increasing chances of suffering mutations that are irreparable. The cellular machinery is such that the basal level of mutations are usually successfully corrected by processes such as Nucleotide Excision Repair (NER) (Lindahl and Wood, 1999). When, for various reasons, they cannot be, then apoptosis ultimately will make the mutations moot. There are several stages in the formation of cancer cells. The first is the initiation stage. During initiation, some mutation has to occur that results in either a loss of function (exemplified by p53, tumor suppressor gene) or a gain of function (e.g., virally derived oncogenes in which there is production of aberrant proteins having normal cellular counterparts). The key is, a mutation needs to occur and not be corrected by the usual cellular mechanism. At this point, cells will typically become described as 'immortalized.' When this occurs, the cells no 32 IJPHA Vol. 1 Issue 4 Spring 2013 The next stage is the promotion/progression stage of cancer development. Now the cancer cell, usually through a result of even more mutations, becomes transformed and no longer acts like a normal cell. The transformed cell is now unrestricted in both its life-span and localization. As stated above, a normal cell will sense its environment and be restricted in its growth. The transformed cell no longer abides by such rules and will multiply, literally piling up on top of its neighbors. Typically there is an associated perturbation of the cellular glycosylation pattern (Dennis et al, 1999; Taniguchi et al, 1999). Also, the morphological structure of the cell itself changes, from being flat with multiple projections to being much smaller and rounded up. They pile up into what is known as a tumor. The tumors are “fed” by new blood vessels formed by a process known as angiogenesis. The final stage is metastasis. Here the cancer cells have progressed to the point where they are no longer localized to one ever-growing tumor. They gain the ability to enter the blood vessels (intravasation), move to a different location in the body, stop and exit the blood vessel (extravasation) and establish a new site of tumor development. Eventually the body becomes riddled with tumors consuming the bulk of available energy. The body is literally eaten alive as evidenced by the cancer associated cachexia (body wasting). Cells in the body undergo this process frequently. However, it is usual for the immune system to pick those cells up and clear them from the body. Cancer is often thought of as an evasion of the immune system. The body has two main routes for the types of cells it makes in response to different threats: B-Cells and T-Cells. B-cells secrete antibodies whereas the T-cells are more interactive and some subsets will actually seek out and destroy cancer cells. Such activity depends on the T-cells activity and viability. DL has been shown to improve T-cell activity and viability (Lappas and Lappas, 2012). In that dreadfully bleak picture of cancer development, there are some valiantly shining points of light. Monoternes, found in essential oils, are such points of light offering some hope in the struggle to prevent and treat cancer. The best news is that DL and POH can not only prevent but also treat cancer. That is to say, the MTs can act before a cancer is established and, in the cases where cancer is already present, they can cause a regression of the tumor. They do this in four ways. First, during the initiation phase of carcinogenesis, they induce (cause the body to make more of) Phase II (Kensler, 1997) carcinogen-metabolizing enzymes, resulting in carcinogen detoxification. An example of such a Phase II enzyme would be glutathione S-transferase (van Lieshout et al, 1998). Second, post initiation phase, they have been shown to increase cell redifferentiation (Gould, 1997). This causes the potential cancer cells to take on a more normal morphology. Third, they can induce apoptosis in otherwise immortalized cells (Yeruva et al, 2007). Fourth, they have been shown to inhibit the isoprenylation (Galli et al, 1997) of the cellular products Ras (Yamamoto et al, 1999) of oncogenes. Simply put, the proteins from oncogenes, which on the whole are cell-growth regulating proteins, need to be modified (referred to as 'posttranslational modification') by a process called prenylation in order to be placed in a membrane where they are active. If the proteins from oncogenes do not undergo isoprenylation, they do not cause the cell to behave as a cancer cell and hence cancer inhibition results. Data Because the metabolites, which vary from species to species, of monoterpenes also show anticancer effects, it is necessary to discuss dosage in the context of the specifics of each study. Most of the data presented are for in vitro or animal models. In rats treated with DMBA (an agent that induces tumor formation), POH and DL had complete regression rates of 81 and 68%. Interestingly, the amount of DL required to achieve these results was four times higher than POH (Gould et al, 1995; Gould et al, 1995). The dosage for mammals in these experiments is suggested to be approximately 2.5g/kg for POH (roughly five times that for DL). The mammalian in vivo data suggests a dose of 7.5 g/m2. In humans, this would translate to approximately 10-15 g/day. While most of the work cited above has been done in rodents, they are not perfect reproductions of human diseases. IJPHA Vol. 1 Issue 4 Spring 2013 33 Human phase I clinical results for POH used in the treatment of advanced malignancies in humans have been reported (Ripple et al, 1998). Dosages ranging from 800 mg/m2/dose to 2400 mg/m2/dose were assayed for tolerability. The main toxicity was gastrointestinal, and included nausea and vomiting, anorexia, unpleasant taste, satiety, and eructation (belching). The main metabolites were perillic acid and dihydroperillic acid. The authors reported evidence of POH efficacy in metastatic colorectal cancer where one out of two colorectal cancer patients of the 15 total evaluable patients in this safety trial was free of tumor. Three other patients in this study had their advanced stage disease (two prostate cancer patients and one patient with adenocystic carcinoma of the salivary gland) stabilized. While the conclusions were not as positive as hoped for, there was some encouragement. The disease was shown to stabilize for six months, although no objective tumor responses were observed. The authors concluded that the dosage interval should be increased and the results of that have not been announced. It should be noted that these were advanced malignancies which had been refractory to prior treatments. Also, the use of 2,400 mg/m2/dose is over three times less than the recommended dosage (Gould et al, 1995). In a telephone conversation in 2000, the Principle Investigator of the above study revealed that resulting Phase II studies are currently ongoing for Breast and Prostate cancer using POH. Additionally, because of problems with the original National Cancer Institute (NCI) formulation (half soy bean oil and half POH in 250 mg capsules) they are currently repeating Phase I studies with a new formulation of 90% POH in 700 mg capsules. Additional problems with the original formulation were the complications that any phytoestrogens present in the soybean oil might contribute to the interpretation of the data. However, the results look promising in that an effect was seen for both breast and prostate cancer. The main study using DL has been reported by a British group who saw disease stabilization for both breast and colon cancer patients using 8g/m2/ day (Vigushin et al, 1998). Presently, there are no 34 IJPHA Vol. 1 Issue 4 Spring 2013 other ongoing studies for DL, although the NCI in the US is said to be considering it. One of the problems with getting a study going for prevention is that large, randomized studies for five or six years need to be performed. It is difficult to get companies interested in doing those, despite the exciting data, because of the huge investment of time and money coupled with the difficulty of patenting the naturally occurring compounds. Toxicology The bulk of the toxicity data for monoterpenes comes from the study of limonene in animals and has been well presented by Von Burg (Von Burg, 1995). To briefly summarize, limonene can cause skin sensitization in susceptible people. A blood clearance rate of 1.1 l /kg/hr has been established with the majority being eliminated through the urine. Immunosupression has been observed in mice. This is particularly interesting because aberrations of the immune system have been postulated for causes of cancer cell proliferation, which seems counter-intuitive. There appears to be no genotoxicity (Ames test) although straight Orange peel oil was found to have slight promotional activity for mouse skin tumors initiated with 7,12-dimethylbenz(a)anthracene (DMBA). However, the promotional activity was not observed when either limonene or straight Orange peel oil was added to the diet, suggesting a relationship between promotion and irritant properties of the straight oil. Similarly, there appears to be no neurotoxicity. It should be noted that when relatively high dosages (2363 mg kg-1) were orally administered to mice, decreased body weight and increased bone abnormalities were observed in foetuses. However, at lower dosages (591 mg kg-1), no effects were seen either maternally or in the foetus. From where does one obtain MTs? Currently, POH use is restricted in the US due to the issuance of an Investigational New Drug (IND) application. Nevertheless, there are major laboratory chemical supply companies which do carry POH as a chemical reagent, although not for human consumption. At this time, the only product on the market in both Europe and the US that the author is aware of is manufactured by Solgar Vitamin and Herb Company (Solgar Vitamin and Herb Company, 2000). Solgar carries a product, in their Gold Specific line, called 'Cell Support,' which contains d-limonene. Hohl R J. (1996). Monoterpenes as Regulators of Malignant Cell Proliferation. Advances in Experimental Med and Biology. 401, p137-46. With the high level of impressive scientific data available on the efficacy and clinical tolerability of these naturally occurring nutrients, the monoterpenes are positioned to take a strong role in the war on cancer. They offer a strong ally for the more established routines of cancer therapy and deserve to be given the attention they are drawing. The next few years will be an exciting time as more and more of the Phase II clinical trials are completed and results reported. The public can expect to see new products, such as DL combined with Red Rice Yeast, which contains lovastatin, whose chemopreventive properties (Broitman et al, 1996) may be additive or synergistic. Until then, enjoy your fruits and vegetables! Jia S S et al. (2012). Induction of apoptosis by D-limonene is mediated by inactivation of Akt in LS174T human colon cancer cells. Oncol Rep. 29 (1), p349-54. References Solgar Vitamin and Herb Company. (2000). Broitman S A, Wilkinson J IV, Cerda S. (1996). Effects of Monoterpenes and Mevinolin on Murine Colon Tumor CT-26 In Vitro and its Hepatic 'Metastases' In Vivo. Adv Exp Med Biol. 401, p111-30. Stark M J, Burke Y D, McKinzie J H, Ayoubi A S, Crowell P L. (1995). Chemotherapy of pancreatic cancer with the monoterpene perillyl alcohol. Cancer Lett. 9, p15-21. Chanthai S et al. (2012). Influence of extraction methodologies on the analysis of five major volatile aromatic compounds of citronella grass (Cymbopogon nardus) and lemongrass (Cymbopogon citratus) grown in Thailand. J AOAC Int. 95 (3), p763-72. Taniguchi et al. (1999). Implications of N-acetylglucosaminyltransferases III and V in cancer: gene regulation and signalling mechanism. Biochimica et Biophysica Acta. 1455, p287-300. Chidambara Murthy K N, Jayaprakasha G K, Patil B S. (2012). Dlimonene rich volatile oil from blood oranges inhibits angiogenesis, metastasis and cell death in human colon cancer cells. Life Sci. 91 (1112), p429-39. Crowell P L. (1997). Monoterpenes in breast cancer chemoprevention. Breast Cancer Research and Treatment. 46, p191-197. Dennis J W, Granovsky M, Warren C E. (1999). Glycoprotein glycosylation and cancer progression. Biochimica et Biophysica Acta. 1473, p2134. Fulton G J, Barber L, Svendsen E, Hagen P O, Davies M G. (1997). Oral monoterpene therapy (perillyl alcohol) reduces vein graft intimal hyperplasia. J Surg Res. 69 (1), p128-34. Galli I, Uchiyama M, Wang T S F. (1997). DNA Replication and Order of Cell Cycle Events: A Role for Protein Isoprenylation? Biol. Chem. 378, p963-973. Gould M N, Crowell P L, Elson C E, Ren Z. (1995). Uses of Perillic Acid Methyl Ester. United States Patent No. 5,470,877. Gould M N, Crowell P L, Elson C E. (1995). Regression of Mammalian Carcinomas. United States Patent No. 5,414,019. Gould M N. (1997). Cancer chemoprevention and therapy by monoterpenes. Environ Health Perspect. 105 (4) Suppl. p977-9. Igimi H, Hisatsuga T, Nishimura M. (1976). The use of d-limonene as a dissolving agent in gallstones. Dig. Dis. 21, p926-939. Kensler T W. (1997). Chemoprevention by Inducers of Carcinogen Detoxification Enzymes. Env Health Perspectives. 105 (4), p965-970. Lappas C M, Lappas N T. (2012). D-Limonene modulates T lymphocyte activity and viability. Cell Immunol. 279 (1), p30-41. Lindahl T, Wood R D. (1999). Quality Control by DNA Repair. Science. 286 (5446), p1897-905. Reddy B S, Wang C X, Samaha H, Lubet R, Steele V E, Kelloff G J, Rao C V. (1997). Chemoprevention of colon carcinogenesis by dietary perillyl alcohol. Cancer Res. 57 (3), p420-5. Ripple G H et al. (1998). Phase I clinical trial of perillyl alcohol administered daily. Clin Cancer Res. 4 (5), p1159-64. Uedo N et al. (1999). Inhibition by D-limonene of gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitroguanidine in Wistar rats. Cancer Letters. 137 (2), p131-6. van Lieshout E M M et al. (1998). Effects of dietary anticarcinogens on rat gastrointestinal glutathione S-transferase theta 1-1 levels. Carcinogenesis. 19 (11), p2055-2057. Vigushin D M et al (1998). Phase I and pharmacokinetic study of Dlimonene in patients with advanced cancer. Cancer Research Campaign Phase I/II Clinical Trials Committee. Cancer Chemother. Pharmacol. 42 (2), p111-7. Von Burg R. (1995). Limonene. J of Applied Toxicology. 15 (6), p495-9. Yamamoto T, Taya S, Kaibuchi K. (1999). Ras-Induced Transformation and Signalling Pathway. J. Biochem. 126, p799-803. Yeruva L et al. (2007). Perillyl alcohol and perillic acid induced cell cycle arrest and apoptosis in non small cell lung cancer cells. Cancer Lett. 257 (2), p216-26. Mark A. Brudnak, PhD, has authored more than 40 peerreviewed scientific and trade journal articles while an undergrad (University of Southern California) and a graduate student (University of Tulsa). Often quoted in the health food industry, cited in the scientific literature, and sought out worldwide, he is a leading expert and speaker in the areas of probiotics, enzymes and functional carbohydrates. IJPHA Vol. 1 Issue 4 Spring 2013 35 Inspire Educate Create Sedona Aromatherapie Aromatherapy Courses & Custom Blends www.sedonaaromatherapie.com 36 IJPHA Vol. 1 Issue 4 Spring 2013 Beneficial Blending for Elder Care: The Scents-ible Solutions Aromatherapy Program Cynthia Loving, Aromatherapist, LMT iStock.com © Andrew Gentry The U.S. Nursing Home Reform Act of 1987 emphasized the importance of residents’ rights and quality of life. In the almost 2.5 decades since its passage, a movement known as Culture Change has brought about many improvements in granting people living in nursing homes more privacy and choices in their daily living. One of the changes addresses the use of unnecessary drugs, excessive dosage, or duration of drug use with a focus on antipsychotic drugs occasionally used for behavior control. This change has opened the door for many integrative therapies, such as massage, reflexology, acupuncture, and aromatherapy, to be introduced into residential settings. In 2001, Jackie Farnell, an aromatherapist, licensed massage therapist, licensed esthetician, and owner of Scents-ible Solutions, was asked to conduct an inservice program at Mattie C. Hall Nursing Home in Aiken, South Carolina, concerning the use of essential oils to lower the stress levels of employees. During the presentation the staff became interested in the possibility of using essential oils for people residing in their Alzheimer’s unit to enhance the physical, mental, emotional, and spiritual wellbeing of the residents and staff. Ms. Farnell created four blends for the residents and three for the care providers. She and Patricia Bishop, RN, the Alzheimer’s unit supervisor at the nursing home, then developed a one-year project to evaluate the benefits of the blends. The results of this study were submitted to the state of South Carolina and the nursing home was awarded the 2003 South Carolina’s “Spirit of Caring Best Practice Initiative” and awarded the Best Practice Award. The study and the award created an interest among many other facilities providing care for people with Alzheimer’s and other forms of dementia - and the word spread. In the years that Ms. Farnell owned Scents-ible Solutions, over 450 facilities began using the blends and numerous family/ friend care providers began incorporating these into their daily routines. In 2010, Jackie Farnell transferred the reigns of Scents-ible Solutions to Cynthia Loving, owner of LovingScents. Within a year of acquiring Scents-ible Solutions, there were four new blends added to the four primary areas of concern to allow room for personal preferences and to reduce the possibility of acclimation and potential decreased effectiveness. There are now 11 blends specifically designed to address anxiety, aggression, insomnia, mental stimulation, undesired weight loss, and stress experienced by care providers. Scents-ible Solutions blends Lowering anxiety and aggression Restore Peace (Decrease agitation, ease confusion, elevate mood, and instill a sense of calm) Grapefruit (Citrus paradisi)-Non-sedative; mentally enlivening; antidepressant (Davis, 1999). Frankincense (Boswellia carteri)*-antidepressant; alleviates anxiety, nervous tension, and stress conditions; releases anger, anxiety, and stress (Davis, 1999; Keville and Green, 2009; Mojay, 1999). * Frankincense is considered to be a “threatened” essential oil. An alternative may be Vetiver (Vetiveria zizanoides). Vetiver is considered an antidepressant, is very relaxing, and eases stress, anxiety, fear, insomnia, and grief (Davis, 1999; Keville and Green, 2009). IJPHA Vol. 1 Issue 4 Spring 2013 37 Tranquility (Cool anger and ease restlessness while bringing clarity and elevating mood) Rosewood (Aniba rosaeodora)* uplifting and enlightening properties reputed to have an overall balancing effect (Battaglia, 2003). Rosalina (Melaleuca ericifolia) calming and relaxing; ideal for sleep and stress disorders; supports deep breathing (Webb, 2000). May chang (Litsea cubeba) antidepressant; alleviates stress and anxiety (Battaglia, 2003). * Rosewood (Aniba rosaeodora) is an endangered essential oil. Due to the high levels of the naturally occurring chemical linalool, an alternative to Rosewood might be Ho leaf (Cinnamomum camphora ct linalool) (Kerr, 1998). Linalool plays a role in the antidepressant and sedative qualities of these two essential oils. Mental stimulation Promote Alertness (Joyful stimulant that enhances memory, activity, and socialization; elevates mood) Orange, sweet (Citrus sinensis) relieves nervous tension and anxiety; energizes; revives interest; harmonizes (Sheppard-Hanger, 1995; Cleary, 2005). Rosemary (Rosmarinus officinalis ct. cineole) antidepressant; circulatory stimulant; stimulates mind and improves memory (Price and Price, 2012; Holmes, 2008). Insomnia Helps Relieve Insomnia and Pain (Decrease pain perception; calm nervous tension; decrease anxiety, exhaustion, mood swings; increase relaxation; aid sleep induction) Lavender (Lavandula angustifolia) mentally and physically balancing and normalizing; relieves insomnia due to physical discomfort, mental stress, anxiety or overactive brain (Davis, 1999; Holmes, 2008). Bergamot (Citrus bergamia) antidepressive; refreshes; relaxes; relieves insomnia; uplifting; antispasmodic (Schnaubelt, 1998; Mojay, 1999; Valnet, 1990; Kerr, 1999). Sweet Dreams (Encourage deep and easy breathing, lessen anxiety and agitation, promote physical and mental relaxation, aid sleep) 38 Fragonia™ (Agonis fragrans) gentle expectorant; analgesic; anti-inflammatory; calming; tranquility inducing (Battaglia, 2003). Lavender (Lavandula angustifolia) mentally and physically balancing and normalizing; relieves insomnia due to physical discomfort, mental stress, anxiety or overactive brain (Davis, 1999; Holmes, 2008). IJPHA Vol. 1 Issue 4 Spring 2013 Marjoram (Origanum majorana) antidepressant; analgesic; antispasmodic; calming; sleep-inducing (Price and Price, 2012; Valnet, 1990; Kerr, 2003; Cleary, 2005; Holmes, 2008). iStock.com © Abel Mitja Varela Vitality (Refreshing, elevates mood, encourages physical and mental activity, encourages deep breathing) Grapefruit (Citrus paradisi) non-sedative antidepressant; mentally enlivening (Davis, 1999). Spearmint (Mentha viridas) antidepressant; lowers stress and metal fatigue; uplifting (Battaglia, 2003). Cardamom (Elettaria cardamomum) emotionally stimulating; relieves stress and anxiety (Keville and Green, 2009). Ginger (Zingiber officinale) warming; invigorating; stimulating (Mojay, 1999). Unwanted weight loss Appetite Stimulant (Elevates mood, energizes and activates digestive system-from salivation to Ylang ylang (Cananga odorata) antidepressive; antispasmodic; eases nervous tension, stress, and anger (Mojay, 1999; Sheppard-Hanger, 1995). peristalsis) Cinnamon leaf (Cinnamomum zeylanicum) antidepressant; antispasmodic; relieves tension; antiinfectious (Keville and Green, 2009; Valnet, 1990; Schnaubelt, 1999). Grapefruit (Citrus paradisi) antidepressant; refreshing; stimulating (Price and Price, 2012). Clove bud (Eugenia caryophyllata) antispasmodic; stimulates digestion; eases nausea; relieves flatulence (Keville and Green, 2009). Bon Appétit (Activates digestive system, eases digestion, antispasmodic) Orange, sweet (Citrus sinensis) antidepressant; digestive stimulant (Price and Price, 2012; Cleary, 2005). Cinnamon leaf (Cinnamomum zeylanicum) digestive stimulant; carminative; antispasmodic (Valnet, 1990; Jefferies, 2007). Grapefruit (Citrus paradisi) non-sedative antidepressant; mentally enlivening (Davis, 1999). Fennel (Foeniculum vulgare) appetite and digestive stimulant; antispasmodic; eases constipation, diarrhea, and nausea; carminative (Davis, 1999; Mojay, 1999; Price and Price, 2012). Stress Reduction (primarily for care providers) Care Giver Relief (Stimulates mental clarity, promotes relaxation, relieves anxiety and nervousness) Orange, sweet (Citrus sinensis) antidepressant; antispasmodic; relaxing; lowers stress (Davis, 1999; Price and Price, 2012; Schnaubelt, 1999; Cleary, 2005). Lemon (Citrus limon) antidepressive; antiinflammatory; antispasmodic; immuno-supportive; eases sadness and anger; clears thought; sharpens focus (Cleary, 2005; Keville and Green, 2009; Price and Price, 2012; Sheppard-Hanger, 1995). Unwind (Mood elevating; grounding; lowers stress, tension, anxiety and nervous strain) Bergamot (Citrus bergamia) antidepressant; uplifting; cooling; refreshing; antispasmodic (Mojay, 1999; Valnet, 1990; Kerr, 1999). Geranium (Pelargonium graveolens) antidepressive; eases anxiety, stress, agitation, and mood swings; balances hormonal system; mental stimulant (Davis, 1999; Cleary, 2005; Keville and Green, 2009; Mojay, 1999; Price and Price, 2012; Shutes, 2012). Patchouli (Pogostemon cablin) antidepressant; antiinflammatory; eases stress and anxiety; grounding; mentally stabilizing (Davis, 1999; Mojay, 1999; Price and Price, 2012; Jefferies, 2007). Utopia (Calming, aids in finding emotional equilibrium, elevates mood, cools frustration) Grapefruit (Citrus paradisi) non-sedative antidepressant; mentally enlivening (Davis, 1999). Geranium (Pelargonium graveolens) antidepressive; eases anxiety, stress, agitation, and mood swings; balances hormonal system; mental stimulant (Davis, 1999; Cleary, 2005; Keville and Green, 2009; Mojay, 1999; Price and Price, 2012). Ylang ylang (Cananga odorata) antidepressive; antispasmodic; eases nervous tension, stress and anger (Davis, 1999; Mojay, 1999; Price and Price, 2012). IJPHA Vol. 1 Issue 4 Spring 2013 39 Primary methods of application These blends were created to be used primarily via inhalation. In most instances it is suggested that one drop of the blend be placed on a self-adhesive felt appliqué (Fig. 1) and adhered to the individual’s clothing – when using with people with dementia, it is best if the appliqué is placed outside of the individual’s visual range (back of shoulder). Some facilities will put 20 drops of the blend in distilled water in a 4 oz (120 ml) mister bottle and spray in the room. When appropriate, Fig. 1 the blends can be diffused into the room. The recommended use for stress relief blends for care providers is a drop of the selected blend on a tissue or terra cotta clay disk to be inhaled as needed. Two or three drops may be used in a diffuser or aromatherapy jewelry. The blend may also be used in an aroma stick for personal inhalation as needed. Why inhalation? Olfaction has a direct tie to the Limbic system. When inhaling essential oils, the volatile molecules ride on the air to the top of the nose where cilia (microscopic, hair-like structures) project from the olfactory receptor cells. From here, an electrochemical message is sent through the olfactory bulb and olfactory tract to an ancient part of the brain known as the Limbic system – once called the Rhinencephalon or “nose brain.” The Limbic system is primarily responsible for our emotional life and plays a major role in the formation and retrieval of memories. From the Limbic system, messages can be sent to other parts of the brain and throughout the body via the blood stream where they may impact mental states through the central nervous system and/or endocrine (hormonal) system. These messages then influence the discharge of neurochemicals that can calm, stimulate, elevate mood, or ease anxiety, depending on the needs of each individual. 40 IJPHA Vol. 1 Issue 4 Spring 2013 Scents-ible Solutions training manual Purchase of the Training Manual is required prior to a facility or professional home care provider instituting the Scents-ible Solutions Aromatherapy Program. Family/friend care providers are not required to purchase the manual but are provided with information concerning the blends they purchase and their appropriate use. The manual includes chapters entitled: What is Aromatherapy A Brief History of Aromatic Medicine Aromatherapy as a Wellness/Healing Tool How does Aromatherapy Work The Mattie C. Hall Nursing Home Study Scents-ible Solutions Protocol Scents-ible Solutions Blends & Methods of Application Appendices: History of Aromatic Plants in the Art and Science of Aromatherapy Sample Aromatherapy Program Policy Statement Sample Consent Form Material Safety Data Sheets The manual contains the results of the year-long study conducted at Mattie C. Hall concerning unwanted weight loss. This study, using the Appetite Stimulant blend, monitored weight changes (static, loss, or gain). At the beginning of the study there were ten residents losing three or more pounds per month. At the end of the study there were two. Simultaneously, they conducted a study concerning the use of psychotropic medications. The blend used for this study was Restore Peace. At the beginning of this year-long study there were nine residents using psychotropic medications. At the end of the study, there were two. There is also anecdotal information provided by staff and family members as to the results they witnessed while residents of family members were using the Scentsible Solutions blends. In addition to the manual, training is provided for the staff of facilities desiring to use the Scents-ible Solutions program. Consultations are offered for those who seek customized blends to meet the specific needs of an individual. Due to HIPPA Privacy Practices, case studies are not available for publication, however the facilities and family care providers shared this anecdotal information: The impact of diffusing Restore Peace or Tranquility in common areas in mid-afternoon through early evening has been reported to lower confusion, agitation, stress, fear, pacing, and other symptoms of sundowning. Individual application on an appliqué has also been shown to ease the aforementioned symptoms in addition to anger, loneliness, and grief. Helps Relieve Insomnia and Pain and Sweet Dreams have been effective in promoting deep relaxation and sleep. It has been reported that Sweet Dreams seems to be more effective with people who have respiratory challenges. Diffusing Promote Alertness or Vitality prior to and during activities often encourages more participation and socialization. Appetite Stimulant and Bon Appétit activate and ease the digestive system. We have heard many times of people who have lost their appetite and the ability of these blends to then reintroduce the desire to eat. The blends addressing the needs of the care givers (Care Giver Relief, Unwind, and Utopia) enable many to ease their stress and grief while offering relief of some of the challenges they encounter. Female, 71 years of age and diagnosed with dementia, became hysterical and combative whenever she was bathed. This facility has a “quiet room” with dimmed lights, calming music, and a water feature connected to the bathing room. For this resident, Tranquility was diffused for three to five minutes prior to her being brought in. She entered the room and sat quietly for about ten minutes. She was then taken into the bathing room where the blend was being diffused. She proceeded with her bath without any signs of agitation or combativeness (a routine repeated with the same results). Wheelchair-bound Male, 76 years of age, was residing in a residential memory unit and diagnosed with dementia. While bored at group activities he would survey the area for a staff member coming his way. He would then take aim for that person and ram his wheelchair into them. After this happened several times, the Recreational Therapist in charge of the Scents-ible Solutions program prepared a self-adhesive felt appliqué with a drop of Restore Peace on it. As the patient began moving toward a staff member, the Recreational Therapist gently placed the appliqué on the front of his shirt and stopped to talk to him. Within a minute, the patient took a deep breath, sighed, and wheeled himself to his room. Female, age 78, living in a care residence and diagnosed with Alzheimer’s disease, refused to eat saying she wasn’t hungry. She would become belligerent when reminded of the need to eat. Due to her weight loss, she was diagnosed with “failure to thrive.” A care provider asked us what might stimulate her appetite. We suggested she put one drop of Bon Appétit in a bowl of warm water, place a washcloth in the bowl, wring it out well, and have her wipe her hands with this about ten minutes prior to mealtime. This was done as directed and she still declined to eat. About ten minutes later she stated she would like to eat. The same blend was used prior to each meal and two and a half weeks later she had gained four and a half pounds. Female, 69 years old and diagnosed with dementia, was always very tired and sleepy. She never participated in activities or family events and would often sleep through family visits. Her memory was seriously impaired. The staff at the facility in which she lived diffused Promote Alertness in the areas where group activities were taking place. Each day during group activities she was escorted past the room and was asked if she would like to go in. The answer was always “no.” After three days, she walked past the room and when asked if she would like to go in, she said “yes.” After that, she participated in many activities and the staff and family noticed she seemed more aware of her surroundings, slept less, and enjoyed increased interaction with other residents, staff and family members. Male, 74 years of age, had been residing in a nursing home for two months recovering from hip replacement surgery and an acquired infection. He was angry at being in a nursing home and complained of pain and inability to sleep. This facility had been using Scents-ible Solutions blends for several years and decided to try Helps Relieve Insomnia and Pain with him at bedtime. They applied one drop of this to his pillowcase and he feel asleep within 15 minutes but woke about two hours later saying he was experiencing some pain. They repeated the application of the same blend and he returned to sleep for another four hours. The next night they placed four drops of the blend in a diffuser and found he was able to sleep longer and did not mention pain. He continued using this blend until he was released. IJPHA Vol. 1 Issue 4 Spring 2013 41 In its 11th year, Scents-ible Solutions continues to grow. It is now being used in numerous types of facilities/programs including nursing homes, rehabilitation centers, hospices and palliative care programs, day care programs for people with dementia, programs for people with developmental disabilities, and schools. Psychologists, social workers, physicians, massage therapists, and other professionals are using some of these blends within their private practices. Price S and Price L. (2012). Aromatherapy for Health Professionals. 4th ed. London: Churchill Livingstone. As individuals and facilities learn more about Culture Change and the Centers for Medicare & Medicaid Services’ Antipsychotic Drug Reduction Program, the call for this and other programs to address the needs of people residing in nursing homes and other related facilities will only grow. Valnet J. (1990). The Practice of Aromatherapy. Rochester, Vermont: Healing Arts Press. References Battaglia S. (2003). The Complete Guide to Aromatherapy. 2nd ed. Brisbane: The International Centre of Holistic Aromatherapy. Battaglia S. http://www.perfectpotion.com.au/Learn-and-Discover/ Learn-about-Australian-oils.aspx Cleary S. (2005). Aged, Frail and Palliative Care. Aromatherapy Today. 33, p26-27. Schnaubelt K. (1998). Advanced Aromatherapy: The Science of Essential Oil Therapy. Rochester, Vermont: Healing Arts Press. Schnaubelt K. (1999). Medical Aromatherapy. Berkley, California: Frog Ltd. Sheppard-Hanger S. (1995). The Aromatherapy Practitioner Reference Manual. Tampa, Florida: Atlantic Institute of Aromatherapy. Shutes J. (2012). Essential Oil Profile: Geranium. The International J. of Professional Holistic Aromatherapy. 1 (1), p24-28. Webb M. (2000). Bush Sense: Australian Essential Oils & Aromatic Compounds. Sydney: Self published. Cynthia Loving was first introduced to aromatherapy and began her studies in the mid-1980s. She has been an aromatherapy educator since 1995 and lectures in medical schools, massage programs, professional associations, other health related institutions/programs, and a wide array of organizations. She is owner of LovingSense Aromatherapy, doing business as LovingScents and Scents-ible Solutions, and offers retail and wholesale essential oils and aromatherapy products. Cynthia is also a licensed Massage and Bodywork Therapist and a Craniosacral Therapist practicing in Greensboro, North Carolina. [email protected], www.LovingScents.com, Natural Spring Cleaning* nd Davis P. (1999). Aromatherapy: An A-Z. 2 ed. London: Vermillion. Holmes P. (2008). Systemic approach to treating depression with essential oils. The International J. of Clinical Aromatherapy. (2), p22-29. Jefferies J. (2007). Cinnamon essential oil. Aroma. Today. 40, p4-9. Jefferies J. (2007). Patchouli essential oil. Aromatherapy Today. 39, p4-9. Keville K and Green M. (2009). Aromatherapy-A Complete Guide to the Healing Art. 2nd ed. Berkley, California: Crossing Press. Kerr J. (1998). Essential Oil Profile Ho Leaf/Rosewood. Aromatherapy Today. 7, p6-9. Kerr J. (1999). Essential Oil Profile Bergamot. Aromatherapy Today. 11, p14-16. Kerr J. (2003). Essential Oil Profile Marjoram. Aromatherapy Today. 26, p10-12. Lawless J. (1992). The Encyclopedia of Essential Oils. Shaftesbury, Dorset: Element Books Limited. Deodorizing Room Spray 2 oz/60 ml distilled water 10 drops Lemon (Citrus limonum) 5 drops Peppermint (Mentha x piperita) 5 drops Rosemary (Rosmarinus officinalis) Directions In a 2 oz/60 ml spray bottle, combine water and essential oils. Shake vigorously and mist into the air. Avoid spraying into eyes or on animals. Mojay G. (1999). Aromatherapy for Healing the Spirit. Rochester, Vermont: Healing Arts Press. Lemon and mint. iStock.com © Olga Brovina *See full article beginning on page 43. 42 IJPHA Vol. 1 Issue 4 Spring 2013 Natural Spring Cleaning Andrea Butje, Clinical Aromatherapist and Linda Byington, RA, Certified Reflexologist iStock.com © franny-anne The Center for Disease Control (CDC) recently estimated that seven pathogens including Salmonella, Toxoplasma, Listeria, Norovirus, Campylobacter, E. coli O157, and Clostridium perfringens, are responsible for 90% of illnesses, hospitalizations, and even death. Most people are concerned with the cleanliness of restaurants and other public places, however 30% of food-borne illnesses are found in the home. The kitchen is known for being a bacteria factory. Kitchen counters, cutting boards, and every knob, drawer and door handle are part of a breeding ground for bacteria to grow. The biggest offender in the spread of nasty microbial trespassers, such as E. coli, Listeria, and Salmonella, is the sponge or dish cloth. They clean up everything from milk spills to raw meat juices and leaky food packages. But after repeated use, how clean are they? The bathroom isn’t much cleaner, either, and may contain many bacterial species that can potentially cause harm if not adequately maintained. Staphylococcus bacteria, which are especially widespread, are frequently found in and around toilets, in showers, on door handles, and in and around the bathroom sink. Essential oils can be just the antimicrobial agents we need. An alternative approach against these germs is to integrate non-toxic cleaning products into your home. Most commercial cleaning products contain chemicals and cleansing agents that are potentially toxic and, when breathed in, some of these substances can irritate the respiratory system. This can cause allergies, headaches and a multitude of other health concerns so it is wise to limit your exposure to chemical toxins. You can safeguard your health by making your own simple, all-natural household cleaners with a few affordable ingredients: Baking soda acts as a natural abrasive deodorizer and cleanser, and is gentle enough to use on most surfaces. Borax is a natural mineral compound that lifts dirt, softens water, and is an insecticide (Woods, 1994). Castile soap is made with fat from a vegetable origin (usually olive oil) rather than animal fats. It is high quality soap, is gentle on the skin and a great cleanser. White vinegar can inhibit the growth of bacteria, including E. coli (Entani E et al, 1998), by creating an unfriendly, acidic environment. Essential oils offer antimicrobial properties for cleaning, such as – Eucalyptus (E. globulus) which is effective for cleaning children's toys to remove house dust mites (Chang et al, 2011) Lemon (Citrus limonum) which is “second to none in its antiseptic and bactericidal properties” (Valnet, 1990) Tea Tree (Melaleuca alternifolia) which is an “anti-infective agent with very broadspectrum of action” (Schnaubelt, 1998) Thyme (Thymus vulgaris) which is effective against food born bacteria including Brochothrix thermosphacta and Staphylococcus aureus, Escherichia coli, Salmonella abony, Pseudomonas aeruginosa and P. fragi (Schmidt et al, 2012) IJPHA Vol. 1 Issue 4 Spring 2013 43 Formulas for Household Cleaners Toilet Bowl Cleaner 1/4 cup/50 gm borax All-Purpose Cleaning Spray 1/4 cup/50 gm baking soda 5 oz/150 ml water 2 tablespoons Castile soap 2 oz/60 ml hydrosol of choice (like Peppermint) 2 teaspoons white vinegar 1 tablespoon Castile soap 2 teaspoons water 1 tablespoon hydrogen peroxide 10 drops Lavender (Lavandula angustifolia) 1/4 teaspoon white vinegar 10 drops Lemon (Citrus limonum) 10 drops Peppermint (Mentha x piperita) 5 drops Thyme (Thymus vulgaris) 10 drops Eucalyptus (Eucalyptus globulus or E. radiata) 20 drops Lemon essential oil (Citrus limonum) Directions In an 8 oz/240 ml wide-mouth container, combine borax, baking soda, and Castile soap. Add white vinegar and water. Add essential oils and mix well. Directions Combine all ingredients in an 8 oz/240 ml spray bottle. Shake vigorously before each use. Avoid spraying into eyes or on animals. References 40 drops White Pine essential oil (Pinus strobus) All-Natural Cleaning Scrub 1 cup/200 gm baking soda 3 tablespoons Castile soap 1 tablespoon white vinegar 15 drops Tea Tree (Melaleuca alternifolia) 10 drops Peppermint (Mentha x piperita) Chang C F, Wu F F, Chen C Y et al. (2011). Effect of freezing, hot tumble drying and washing with eucalyptus oil on house dust mites in soft toys. Pediatr Allergy Immunol. 22 (6), p638-641. Entani E et al. (1998). Antibacterial action of vinegar against foodborne pathogenic bacteria including Escherichia coli O157:H7. J Food Prot. 61 (8), p953-959. Schmidt E, Wanner J, Hiiferl M et al. (2012). Chemical composition, olfactory analysis and antibacterial activity of Thymus vulgaris chemotypes geraniol, 4-thujanol/terpinen-4-ol, thymol and linalool cultivated in southern France. Nat Prod Commun. 7(8), p1095-1098. Schnaubelt K. (1998). Advanced Aromatherapy. Rochester, VT: Healing Arts Press. 15 drops Sweet Orange (Citrus sinensis) Valnet J. (1990). The Practice of Aromatherapy. Rochester, VT: Healing Arts Press. Directions In a 16 oz/480 ml wide-mouth container, mix all ingredients. Add more vinegar or Castile soap as needed to make a smooth consistency. Vizcaya D, Mirabelli M C, Antó JM et al. (2011). A workforce-based study of occupational exposures and asthma symptoms in cleaning workers. Occup Environ Med. 68 (12), p914-919. Cutting Boards To keep wooden and plastic cutting boards free of bacteria, use a few drops of Lemon (Citrus limonum) essential oil to clean the cutting board. First, wash the board with hot water and castile soap. Then put about five drops of Lemon essential oil on a clean sponge and wipe the board vigorously, front and back. The “side effect” is that the sponge is now also clean and bacteria free. Andrea Butje has been teaching courses in the medical uses of essential oils since 1995. In addition to writing course materials and working with essential oil distillers, Andrea developed The Aromahead Institute’s Component Database containing current scientific research of the chemical constituents of essential oils. www.aromahead.com 44 IJPHA Vol. 1 Issue 4 Spring 2013 Woods WG. (1994). An introduction to boron: history, sources, uses, and chemistry. Environ Health Perspect. 102 (Suppl 7), p 5–11. Linda Byington became a Registered Aromatherapist in 2003 and is a Certified Reflexologist. In addition to her private practice, Linda teaches aromatherapy workshops and lectures locally. www.elementalaromas.com Blind Leading the Blind: Essential Oils in Eye Care Robert Tisserand, Essential Oil Consultant © Lora Cantele There has been much social media discussion recently (February 2013) about the wisdom or otherwise of putting essential oils into your eyes to treat eye problems. This arose from two web pages: http://www.livestrong.com/article/123613-essentialoils-eyes/ http:// aromatherapyliving.wordpress.com/2013/02/12/clearvision-with-natural-eye-drops/ The Livestrong article states: “More and more people are choosing to use alternative medicines to treat minor illnesses rather than taking a prescription. Putting essential oils in or near the eyes isn't something that is widely known about, but there are several that can aid in the treatment of eye problems. Before using essential oils for your eyes, always contact your doctor. Clary sage is the essential oil that is most widely used to treat vision problems. It is placed in the eye, so advice from an optometrist is important before use. Clary sage is used as a cleanser for the eyes. It can also be used to clear eye sight due to foggy vision or an injury to the eyes. Clary sage can also be used to brighten the eyes and improve vision. Finally, it can have beneficial results for people with eye issues related to aging.” This actually dates from May 2010 but, judging from the related comments, has only recently been noticed. The statement that “Clary sage is the essential oil that is most widely used to treat vision problems” is not true, since there are no essential oils commonly used to treat vision problems. The only evidence for any essential oil treating any eye prob- lem relates to Tea tree (Melaleuca alternifolia) oil and eyelash mites (see below). The reference to Clary sage probably derives from 17th century European herbalists, but this refers to using Clary sage seeds, or mucilage made from them, and not to Clary sage essential oil: “The seed put into the eyes clears them from motes and such like things gotten within the lids to offend them, and it also clears them from any white and red spots which may be on them (Culpeper, 1652). Another common name for Clary sage (Salvia sclarea) was “clear eye” because of this common use of the seeds, which pre-dated Culpeper by many years. “Clary” may derive from “clear-eye.” Not only is there no evidence that any essential oil can help with vision problems, age-related or otherwise, but placing any essential oil “in the eye” is extremely dangerous advice. Almost any undiluted essential oil coming into contact with the ocular membranes will be corrosive, possibly causing scarring of the cornea, and certainly causing significant pain. Eye damage I could find no reports in the literature of ocular accidents involving single essential oils, but there are several for Olbas oil (Figure 1). This is a mixture of essential oils (species not specified) and menthol: 35.45% Eucalyptus oil 35.45% Dementholized mint oil 18.5% Cajuput oil 4.1% Menthol 3.7% Wintergreen oil 2.7% Juniper berry oil 0.1% Clove oil Fig. 1 Olbas oil Nasal Decongestant IJPHA Vol. 1 Issue 4 Spring 2013 45 A 2009 report from an ophthalmologist in Bristol UK, describes partial loss of corneal tissue (i.e. erosion) when a 73-year-old man dripped Olbas Oil into his left eye (he had no right eye) because he thought Fig. 2 Courtesy of Naure Publishing Group he was using eye drops (Figure 2). He was “considerably incapacitated.” but recovered after a week of treatment with “topical antibiotics and lubricants.” On checking, the author found that just his hospital, in the previous 18 months, had seen 12 patients who had mistakenly dripped Olbas Oil into one eye. He describes the result as a chemical burn, though he found that Olbas Oil in tears was pH neutral (most chemical burns are caused by substances that are strongly acid or alkaline). All “Olbas Oil patients” recovered fully within one week following intensive treatment (Adams et al, 2009). Olbas Oil may cause problems even when not applied directly to the eyes. The mother of a fourmonth-old boy placed several drops of Olbas Oil in his right nostril in an attempt to help his respiratory infection, not realizing that the product warns against use in infants. The child immediately showed signs of respiratory distress and was taken to the emergency room. Two hours after admission his eyes became inflamed and examination revealed bilateral superficial corneal scarring. He also had conjunctivitis and could not open his eyes. They were flushed with saline over four days and he recovered with no residual scarring (Wyllie and Alexander, 1994). Emergency treatment More than 65,000 work-related eye injuries and illnesses are reported annually in the USA, a “significant percentage” of these being ocular chemical burns. They require rapid treatment, and severe burns have a poor prognosis. The standard treatment is copious irrigation with saline solution for 1-2 hours. Contact lenses should not be removed initially (Peate, 2007). With essential oils, fatty oil has been suggested as an appropriate first aid treatment though the advantage of saline is that the eyes can be continually flushed and this is less easy with fatty oil. 46 IJPHA Vol. 1 Issue 4 Spring 2013 What about diluted essential oils? The second article describes using essential oils diluted to (by my estimation) about 3%. It includes the following advice: “Here is a truly natural solution, which has been shown to benefit your eye health and the only one I will use. Gary Young has used this recipe for his patients at the Ecuador Clinic for macular degeneration, health issues, cataracts, and improving sight. I’ve been using it for a couple of years and love it! I started using this recipe before I had to have a vision exam in order to purchase new contacts. And I knew my vision had deteriorated from my last exam. So I put the drops in my eyes every night for about six months prior to the exam and my prescription had not changed according to their records, but I know what I was not seeing and I know what I was seeing as a result of using these drops – clearly my vision had improved! The recipe is as follows: 7-10 drops of Frankincense 7-10 drops of Rosemary 7-10 drops of Cypress 2 Tbsp of V-6 Put oils in a glass dropper bottle with a lid on it. My experience has been that I can see much more clearly just after putting the drops in my eye so I am also going to experiment with putting a drop in my eyes in the morning (Ewald, 2012).” “V-6” is a proprietary blend of vegetable oils. The above implies that using these oils on a daily basis is likely to have a healing effect in cases of cataract, macular degeneration, or failing eyesight. Although the article continues to describe various effects of the essential oils, none of them have any relationship with any of these conditions. So the question arises – how to weigh potential benefits against potential risks? The word “experiment” in the above seems appropriate. Eyesight problems are difficult to treat and, once damage has occurred, recovery is not always simple. A 3% dilution may not be sufficient to cause corneal erosion, but on the other hand there is no evidence of any benefit. One concern is that the wrong dilution may be used, and the risk of this is substantial. For example, it would be easy to confuse “tbsp” with tsp,” resulting in a dilution of about 10% instead of 3%. In a Chinese study, an ointment containing 5% Tea tree oil was used by patients whose eyelash follicles were infested with “eyelash mites” (Demodex folliculorum). The ointment was applied to the lid margins with eyes closed, daily for 4 weeks after washing the face, and resulted in considerably less itching and fewer mites. Two of the 24 patients experienced slight irritation from the ointment. The 5% concentration was arrived at after preliminary testing using various dilutions on rabbit eyes (Gao et al, 2012). Robert Tisserand is recognized in the aromatherapy industry as a leader and world expert. He has spent 15 years as a massage therapist, 12 years as a publisher/ editor, 18 years as an educator, and 35 years developing personal care products. In 1988, he founded The Tisserand Institute, setting new standards for vocational aromatherapy education. Mr. Tisserand spends much of his time tracking all the published research relevant to essential oils and often collaborates on projects with doctors, herbalists and pharmacologists. www.roberttiserand.com Business Tip Conclusions Andrea Butje, Clin. Aromatherapist Undiluted essential oils should not be applied to the eyes. It is rash to suggest that essential oils are commonly used to treat eye problems. Are you using both Pinterest and Facebook? Eye injuries and diseases are medical conditions, and any product claiming to treat them is a medicine, subject to drug legislation. There is currently no evidence that applying dilutions of essential oil into the eyes will be beneficial in any condition. Pinvolve provides tools that let you and your fans share your Facebook picture posts on Pinterest, and include your Pinterest pins on your Facebook profile! Diluted (5%) Tea tree (Melaleuca alternifolia) essential oil may help eradicate eyelash mites, but it should not be placed into the eyes. References Adams M K, Sparrow J M, Jim S et al. (2009). Inadvertent administration of Olbas oil into the eye: a surprisingly frequent presentation. Eye (London). 23, p244. Culpeper N. (1652). The English Physitian, or an Astro-physical discourse of the vulgar herbs of this nation. Being a compleat method of physick, whereby a man may preserve his body in health; or cure himself, being sick. London: Thomas Kelly Ewald D. (2012). Clear vision with natural eye drops. http:// aromatherapyliving.wordpress.com/2013/02/12/clear-vision-withnatural-eye-drops/ Gao Y Y, Xu D L, Huang I J et al. (2012). Treatment of ocular itching associated with ocular demodicosis by 5% tea tree oil ointment. Cornea. 31, p14-17. Peate W F. (2007). Work-related eye injuries and illnesses. American Family Physician. 75, p1017-1022. Wyllie J P, Alexander F W. (1994). Nasal instillation of ‘Olbas Oil’ in an infant. Archives of Disease in Childhood. 70, p357-358. The Pinvolve app creates a new area on your Facebook page showing all your Facebook photo posts in a beautiful and appealing display. Your Facebook “likes” and the comments associated with each post will also show up. When you place your curser over an image, you are invited to pin, tweet or share the post. Click the “pin” button, and the app will post your content to your Pinterest board of choice. Click the “share” button and your pin gets posted to your Facebook profile. To set up Pinvolve, simply log onto your Facebook business page and use this link: www.pinvolve.co. Once you install the Pinvolve app, it is located on the top of your Facebook page just under your cover photo in the section called your “favorites,” where photos, “likes” and events are also located. You can visit my Aromahead Institute Facebook page to see how Pinvolve looks and functions by going to www.facebook.com/Aromatherapyeducation. IJPHA Vol. 1 Issue 4 Spring 2013 47 Book Review Anita James, SPdipA, MIFPA, Cert Ed. Essential Oils – A Handbook for Aromatherapy Practice 2nd Edition by Jennifer Rhind I must admit to the fact that I feel I’ve known this book for a long time and have watched it blossom into this wonderful publication. I first saw it some years ago in its draft stage when Sue Jenkins, who was then a fellow IFPA council member and work colleague of Jennifer’s, brought it to the IFPA conference to see if therapists and students would be interested in buying a copy. It obviously past this test. Soon it appeared on my Amazon recommendations list and I purchased a copy that has now become one of my ‘go to’ books and is very well thumbed. On seeing that a 2nd version (revised edition) had been released I went through the ‘do I need it?’ ponderings. This however didn’t take long and I can honestly say I’m glad I bought it. The preface sets the scene and conjures up wonderful pictures of childhood and aromas. After reading this and talking to other aromatherapists, I am convinced that we are destined from an early age to enter this love affair with scents and aromas, tempting us deeper into a world where there is definitely no return. This 2nd edition has essentially doubled in size from the first one. It is divided into three sections. The first supplies the essential knowledge of aromatherapy. The second focuses on blending essential oils, going into detail about the various styles and methods. The third and final section provides profiles of not just ‘true’ essential oils but also resinoids and absolutes. I loved the fact that, in the history section, Jennifer left out the ‘ancient history’ and focused on the ‘recent history,’ bringing to life authors that are respected and cherished as pioneers and evolutionaries of this aromatic discipline. 48 IJPHA Vol. 1 Issue 4 Spring 2013 The second section on the approaches to creating an essential oil synergy gave me food for thought about how I approach blending essential oils and creating blends. The author starts with the concepts of synergy and antagonism, expanding this out to cover the concepts of blending essential oils, whilst covering perfumery, the five elements, Ayurvedic theories, and the chakras. Since reading this section, I have fallen down the ‘aromatic rabbit hole’ and spent hours playing with blends and using different principles in my blending and then comparing the results. The third section may become the ‘go to’ section. It covers plant taxonomy, anatomy, and classification. Each family and genus are documented along with uses and relevant substantiating evidence. Absolutes and resinoids are covered in their own chapter. A glossary is included at the back of the book along with extensive appendices, references, and suggestions for further reading. My only criticism is that while many hours have been spent researching and adding information in this new edition to confirm and substantiate the text, it is not possible to read and evaluate it yourself unless you have access to a university library or pay a hefty on-line subscription. This book is sure to become one of the classic aromatherapy texts. It is an affordable, accessible book that I will be using myself, recommending to others, and using with my students. Published by Singing Dragon ISBN: 978-1-84819-089-4 List price: $35.00 Recipes from the Sensual Kitchen Blood Orange Shrimp and Cool as a Cucumber Soup Kris Wrede, Aromatic Alchemist iStock.com © Daniel Loiselle Blood Orange Shrimp Cool as a Cucumber Soup 4 Tbl. key lime juice 2 Tbl. honey or agave nectar 2/3 cup/168 gm frozen orange juice concentrate, thawed slightly 10 drops lemon (Citrus limon) essential oil 1 1/2 Tbl. soft crystallized ginger, finely chopped 2 tsp fresh dill 3 Tbl. lemon curd juice of 1 lime 1/4 cup + 2 Tbl./89 gm brown sugar I green pepper, chopped 1/4 cup/85 gm honey 2 cucumbers, peeled and chopped 10 drops lime (Citrus medica) essential oil 3 cups/681 gm plain non-fat yogurt 30 drops blood orange or orange (Citrus aurantium var. sinensis per.) essential oil 1 cup/120 ml lime flavored mineral water 40-50 raw shrimp Soak 10 wooden skewers in water. Mix the first five ingredients together in a medium size bowl and set aside. 1/2 cup/10 gm fresh mint sea salt to taste Mix the essential oil in the agave or honey. Then put all ingredients in a blender and blend until smooth. Serves 10 Warm the honey, then add the essential oils to the honey. When incorporated, add honey to the bowl. Stir together, then add cooked thawed shrimp and let marinate in the refrigerator for a few hours. iStock.com © Maren Wischewski Set oven shelf so that the broiler pan is about 7”/18 cm below the flame. Place 4 to 5 shrimp on each skewer and broil in oven 5 to 7 minutes on each side. Serves 10 Kris Wrede has been practicing aromatic alchemy and perfumery since 1990 and is a dedicated teacher and researcher. Kris teaches classes in cooking with essential oils at private homes and in cooking schools. The safety measures (page 50) are the result of 15 years cooking, baking, experimenting, sampling and teaching. For upcoming class information visit www.kismetpotions.com IJPHA Vol. 1 Issue 4 Spring 2013 49 Cooking with Essential Oils Basics Essential oils are very strong so they should never be used in large amounts; sometimes no more than a drop is needed. To be used properly a few guidelines are listed below: 1. Use in moderation. 1 drop of stronger oils is usually enough. Good To Know... Aloe vera gel is one of NCCAM's top 5 most searched for herbs http://nccam.nih.gov/health/providers/digest/ topsupplements-science?nav=cd#aloevera Stronger oils are: Basil, Black Pepper, Clove, Coriander, Cumin, Dill, Geranium, Ginger, Lemongrass, Nutmeg, Oregano, Peppermint, Rosemary, Sage, Spearmint, Tarragon, and Thyme. Milder oils are usually citrus and flowering herb oils such as: Bergamot, Blood Orange, Chamomile, Fennel, Lavender, Lemon, Lime, Mandarin, Orange, Petitgrain, and Tangerine. You already consume many essential oils in many foods, beverages, teas, toothpastes, liqueurs, and medicines. 2. Dilute with another fatty or lipid substance when using for any type of cooking or baking. Other fatty substances are butter, cooking oils such as olive or canola, agave nectar, or honey. They will disperse in alcohol and liqueurs nicely. Make sure the oils are well mixed in the other fat or alcohol before using in cooking or baking. Pour oils into a spoon first before adding the fatty substance so you don't get too much. If you get too much, divide it or start over. Be careful since the drops (especially the citrus) come out of the bottle very fast, so go slow and be patient. 3. Use only organic, ecocert or wild harvested essential oils. 4. Store essential oils covered in a cool dark place. 5. Keep out of reach of children, and be careful of using while pregnant. Courtesy of Kris Wrede, Aromatic Alchemist from the Sensual Kitchen www.kismetpotions.com 50 IJPHA Vol. 1 Issue 4 Spring 2013 Aloe vera © Holistic Photo Aloe vera gel effective against multi-drug resistant organisms A recent study finds Aloe vera gel to be affordable and effective against multi-drug resistant organisms as compared to the routinely used topical antimicrobial agents. Reference Banu A, Sathyanarayana B C, Chattannavar G. (2012). Efficacy of fresh Aloe vera gel against multi-drug resistant bacteria in infected leg ulcers. Australas Med J. 5(6), p305–309. Aloe vera mouthwash to reduce radiation-induced oral mucositis Radiation-induced mucositis is a common and dose limiting toxicity of radiotherapy among patients with head and neck cancers. Patients undergoing radiation therapy for head and neck cancer are also at increased risk of developing oral candidiasis. A recent study suggests that Aloe vera mouthwash may reduce radiation-induced oral mucositis in these patients. Reference Ahmadi A. (2012). Potential prevention: Aloe vera mouthwash may reduce radiation-induced oral mucositis in head and neck cancer patients. Chinese Journal of Integrative Medicine. 18 (8), p 635-640. Save the date! International Congress of Aromatherapy and Medicinal Plants Topics include: Phyto-aromatherapy research, cutting-edge applications in healthcare, and women’s and pediatric care in clinical settings. Free entry to the Wellness Expo Sunday afternoon! More information available at: www.ville-grasse.fr/phytarom www.ville-grasse.fr/english