2011 Annual Report - NorthShore University HealthSystem

Transcription

2011 Annual Report
Medical Group
Department of Surgery
Chairman’s Letter
Contents
Clinical Growth
2
Surgical Education
3
Surgical Research
and Clinical Trials
4
Translational Research
7
Selected Honors
9
Divisional Summaries
10
Cardiac and Thoracic Surgery
General Surgery
Neurosurgery
Ophthalmology
Otolaryngology
Plastic Surgery
Surgical Oncology
Urology
Vascular Surgery
Philanthropy19
2011 Peer-Reviewed
Publications and
Book Chapters
20
Staff Directory
24
NorthShore University HealthSystem (NorthShore) has a
long tradition of providing leading-edge surgical care to the
community it serves. The Department of Surgery has kept
pace, and indeed has led the way. Within the Department,
NorthShore has made extraordinary investments in 21st
Mark S. Talamonti, MD
century technologies, translational research and the highest
Chairman of Surgery
caliber of surgeons who are renowned in their respective
Stanton and Margaret Rogers Palmer
specialties and who show steadfast commitment to their
Chair of Surgery
patients while mentoring and teaching future generations
of surgeons.
2011 is no exception, vividly illustrating the Department of Surgery’s commitment to
NorthShore’s mission “to preserve and improve human life” through excellence in clinical care,
research and education. These accomplishments are highlighted in this Annual Report.
The achievements of the Department begin, first and foremost, with the talented surgeons
from our nine divisions, which are summarized in this report. We had several key recruitments
this past year, strengthening our capabilities within the Department. NorthShore is indeed fortunate
to have an extraordinary cadre of superb clinical surgeons with demonstrated academic accomplishments whose top priority is outstanding patient care. In 2011, a number of these surgeons
were ranked by US News & World Report in the top 1 percent of surgeons in the nation.
Leading-Edge Capabilities
In recent years, developments in operating room technology and minimally invasive surgical
techniques have transformed most surgical subspecialties. NorthShore has kept pace with
these advancements.
In 2011, the state-of-the-art, 13,000-square-foot NorthShore Center for Simulation and
Innovation (NCSI) was opened at NorthShore Evanston Hospital. NCSI is designed specifically
for multispecialty, multidisciplinary simulation. It is a leading resource for surgeons both to train
in established minimally invasive techniques and develop and test new methods and procedures—
essentially, it is the surgeons’ research lab.
NCSI received accreditation as a comprehensive Level I program from the American College
of Surgeons (ACS) Education Institute. This is the highest status awarded by ACS, which seeks
to build a community of institutions interested in furthering surgical education.
NorthShore is leading the way in using the most advanced surgical equipment and establishing surgical excellence in areas such as endoscopic surgery, minimally invasive procedures
In 2011, NorthShore continued
to lead the way in providing
leading-edge surgical care
with our new state-of-the-art
endovascular suite at
Evanston Hospital
and Natural Orifice Transluminal Endoscopic Surgery (NOTES). Our surgeons are doing more with
less invasive surgery and performing more complicated clinical surgery with less invasive technologies.
Research
The Department of Surgery at NorthShore has a collective goal for our division members to increase
participation in clinical trials, as well as to author and create clinical trials that will have an impact upon
patient care.
As these pages show, our surgeons are participating in various relevant clinical trials and
research projects, many with leadership roles. Their innovative and participative approach to move
new and better concepts of care into the clinical arena is evident. The active involvement and
commitment by our surgeons to clinically relevant research is equally important to outstanding
patient care now and well into the future.
Education
Given NorthShore’s stature as the primary teaching affiliate of the University of Chicago Pritzker
School of Medicine, our surgeons play an integral role as mentors and educators to residents, interns
and medical students. Our attending physicians hold academic appointments at the University. As an
academic medical center, we create an exhilarating environment in which to learn and discover—this
is true not only for future physicians, but also for the members of our Department.
Across all of our divisions, many of our surgeons have been recognized with various teaching
awards, while others are involved in various academic endeavors, research programs and lectureships
that demonstrate the dedication of our staff to lifelong learning. It is not surprising that many of our
surgeons themselves received training at NorthShore and have come back to practice here and
mentor up-and-coming surgeons.
The Department of Surgery has built on NorthShore’s 120-year history of growth, innovation and
commitment to patient care. We are proud to share these accomplishments with you.
Sincerely,
Chairman of Surgery
Stanton and Margaret Rogers Palmer Chair of Surgery
Dr. Michael Ujiki, Director
of NorthShore’s Center for
Simulation and Innovation,
bridges advances in
Minimally Invasive Surgical
technology and innovative
strategies in Surgical
Education with his commitment to establish NorthShore
as a center of surgical and
teaching excellence.
Department of Surgery 2011 Annual Report 1
200
10,000
100
0
Clinical Growth
Over the past four years, under the leadership
of Department Chairman Mark S. Talamonti,
MD, our clinical volume has grown steadily.
Key recruitments in the Department and
NorthShore’s ability to lead the region in
minimally invasive surgical techniques and
advanced technologies have helped fuel this
growth.
2007
2008
2009
2010
2011
0
Num
Number of Surgical Procedures in the OR
Number of Surgical Procedures
15,000
13,085
12,000
10,645
9,823
14,221
10,890
60,000
45,000
9,000
30,000
6,000
15,000
3,000
0
Work RVUs
Work RVUs
500
300
445
300
286
337
346
337
346
445
475
40,000
475
40,000
30,000
30,000
286
100
2007
2007
2008
2008
2009
2010
2009
2010
2011
2011
600
0
13,085
15,000
12,000
12,000
9,823
9,000
9,823
29,131
34,080
32,578
29,131
Number of
IRB Approved CLinical Trials
111
84
10,645
10,890
10,645
10,890
13,085
2007
2007
2008
2008
2009
2009
2 NorthShore University HealthSystem
2010
2010
55
55
52
2009
2010
2011
2009
2010
2011
Number of established patient office visits
Number
of Established
Patient
Office Visits
Number of established
patient office
visits
2007
2008
2009
14,221
60,000
14,221
60,000
48,272
45,000
48,272
NorthShore’s investment in surgical technology and
9,000
equipment has contributed to an overall increase in
6,000
surgical procedures performed at our hospitals over
the past four years. Since 2007, the number of surgi6,000
cal procedures has increased 69 percent. New patient
3,000
office visits and the number of established patient
3,000
office visits have also continued to climb.
0
34,080
32,578
0
40
20
0
Number of New Patient Office Visits
10,000
80
10,000
100
15,000
2011
20,000
100
200
0
2010
120
20,000
200
0
2009
(in thousands)
500
400
2008
(in thousands)
400
2007
2011
2011
45,000
35,251
30,000
35,251
2010
2011
51,846
51,846
30,000
15,000
15,000
0
0
2009
2010
2011
2009
2010
2011
0
Surgical Education
The NorthShore Department of Surgery has a full spectrum of educational
offerings, beginning with undergraduate medical education and including
graduate medical education for residents and fellows. Our programs also extend to physicians’ assistants and to faculty continuing medical education. We have
hosted courses for our own faculty and for visiting faculty from other institutions who come to NorthShore
to take advantage of our expertise.
NorthShore is the primary teaching affiliate of the University of Chicago Pritzker School of Medicine.
Our joint programs with the University of Chicago continue to grow and mature, providing mutual benefit
to both institutions. The recent opening and accreditation of the NorthShore Center for Simulation and
Innovation (NCSI) affords us the opportunity to expand our educational programs and to have a profound
impact on the future of surgery and surgical education.
2011 University of Chicago Appointments/Promotions
Clinical Professor: Richard Prinz, MD
Clinical Associate Professor: Tina Desai, MD, and Navyash Gupta, MD
Clinical Assistant Professor: Michael Blum, MD; Subhasis Chatterjee, MD; Troy Close, MD; Theodore Eller, MD;
Omar Morcos, MD; Veeral Sheth, MD; Marc Singer, MD; Mark Sisco, MD and Jeremy Warner, MD
Nancy Schindler, MD
Vice Chairman of
Surgery for Education
Graduate Medical Education Programs
• University of Chicago General Surgery Residency Program received maximum five-year accreditation from
the American Council of Graduate Medical Education (ACGME).
• University of Chicago Surgical Oncology Fellowship also received full five-year accreditation from the Society
for Surgical Oncology. These accreditations reflect the high quality of our educational programs.
• The Department of Surgery contributes significantly to the education and training programs at the University
of Chicago Pritzker School of Medicine, supporting the education of surgical fellows, residents and
third- and fourth-year medical students in multiple surgical disciplines. Additionally, University of Illinois
Otolaryngology residents also rotate through NorthShore.
Teaching Awards
• In recognition of her outstanding contributions to medical education, Nancy Schindler, MD, has been
inducted into the prestigious Academy of Distinguished Medical Educators at the University of Chicago. • NorthShore faculty receiving Teaching Excellence Awards from the University of Chicago Department of
Surgery include: Omar Morcos, MD; Marc Singer, MD; James Spitz, MD; Mark Talamonti, MD; Michael
Ujiki, MD; David J. Winchester, MD; David P. Winchester, MD and Katharine Yao, MD. • Ophthalmology—Marian Macsai, MD, was honored with Teacher of the Year Award from the Division of
Ophthalmology at the University of Chicago. New Educational Programs
• Teaching Effectiveness—Nancy Schindler, MD, has implemented a new Teaching Effectiveness Faculty
Development program, and 11 NorthShore surgical faculty members are participating.
• Open Surgical Skills Curriculum—Katharine Yao, MD, has been appointed to lead a new Open Surgical
Skills Curriculum for University of Chicago general surgery residents. Recent Grants Awarded
• Medical Education Grant—NorthShore has received a medical education grant from the University of
Chicago Graduate Medical Education Committee entitled “Pilot Curriculum for Teaching Residents Single
Incision Laparoscopic Surgery: A Patient Safety Initiative.” This is a three-year grant totaling $40,000. Selected Educational Presentations
Nancy Schindler, MD, Vice Chairman of Surgery for Education, made several surgical education presentations
at national meetings including:
• “The Resident Personal Learning Plan: One Step Toward Lifelong Learning”—Association for Surgical
Education, San Antonio, Texas, April 2010. • “Valuable Teachers Should Be Valued”—Association for Surgical Education, Boston, Mass., March 2011.
Surgical Research and Clinical Trials
Surgical Research
Surgeons at NorthShore participate in a wide
variety of relevant clinical trials and research
projects, many with leadership roles.
To support its members in these important endeavors, the
Department includes a Surgical Research Office designed to
advance the medications, instrumentations and technologies used
in the field of surgery. The surgical research team is composed of
dedicated staff—including physicians, nurses and research associates—who are specifically trained and certified in clinical research.
Surgical Research Office staff partner with surgeons to assist
patients through the clinical trial process. This can include helping
identify patients who qualify for clinical trials, determining eligibility,
obtaining informed consent, monitoring adherence to the protocol,
representing investigators to research and regulatory organizations,
collecting data and ensuring that data is validated. The office also
maintains a variety of clinical databases and coordinates the collection of solid tumors for the institution’s biospecimen repositories.
Judi O’Leary (seated center) leads a research office consisting
of 20 research associates conducting investigations in more
than 100 active clinical surgery trials.
Surgical Research Organizational Chart
Chairman,
Charles Brendler, MD
Vice Chairman,
Research and Development
Marshall Baker, MD, MBA
Associate Vice Chairman,
Surgical Research
Judith O’Leary, RN,
OCN, CCRP
Administrative Director
CORE Surgical Research Office
Divisional Satellite Research Offices
Ujala Bokhary, MBBS
Research Associate
Breast Surgery
Tomasz Czechura, MS
Research Associate
Pancreatic Surgery
Michael Kamradt, BS
Project Coordinator
Brigid Martz, BA, CCRP
Clinical Research Associate
Susan Jane Stocker, LPN,
BLS, CCRP
Administrative Coordinator
Klara Agnes Brugger, RN
Clinical Research Nurse
Marna Burright, RN, BSN, CCRP
Michelle Catalano, BS, CCRP
Research Study Coordinator
Michele Corrado, RN, BA
Karen O’Hara, BS, MT, ASCP
Jaclyn Pruitt, MA
Sarah Rabbitt, RN, BSN, CCRP
Mary Turk, CTR, CCRP
Breast Study Database
Manager
Minimally Invasive
Surgery
JoAnn Carbray, BS, CCRP
Amy Yetasook, BS
Research Assistant
Ophthalmolgy
Mira Shiloach, MS
Lissa Silver, PhD
Research Scientist
Plastic Surgery
Brooks Johnson, MD
Research Associate
Veronica Rundell, PhD
Vascular Surgery
Karen Hynes, BS
Number of IRB Approved CLinical Trials
Number of IRB-Approved Clinical Trials
120
111
100
Clinical Trials
84
Clinical trials are vital to testing new treatments
that may ultimately improve patient care.
The NorthShore Department of Surgery has a dedicated
research team that currently oversees more than 100 clinical
studies, all of which have been approved by our Institutional
Review Board (IRB). Listed here is a sample of our current
clinical research studies.
80
55
55
52
2007
2008
2009
60
40
20
0
2010
2011
2011 Selected Clinical Research Studies
Investigator
Clinical Trial
Sponsor
Division of Cardiac and Thoracic Surgery
Investigator
Clinical Trial
Sponsor
Division of General Surgery (continued)
Chatterjee CONVERT: High-Intensity Focused Ultrasound Application in the Surgical Treatment of Atrial Fibrillation Industry
Howington Establishment and Maintenance of a Comprehensive Data Registry and
Tissue Bank for Lung and Esophageal
Malignancies
NorthShore
Howington
ACOSOG Z4032: A Randomized Phase III Study of Sublobar Resection Versus Sublobar Resection plus Brachy-therapy in High Risk Patients with Non-Small Cell Lung Cancer,
3 cm or Smaller
National
Cancer
Institute
(NCI)
Howington
ACOSOG Z4051: A Phase II Study of NCI
Neoadjuvant Therapy With Cisplatin,
Docetaxel, Panitumumab plus Radiation
Therapy Followed by Surgery in Patients
With Locally Advanced Adenocarcinoma
of the Distal Esophagus
Ujiki
Establishment of a Prospectively Maintained Database to Evaluate
Outcomes Following Repair of
Abdominal Wall Hernias
NorthShore
Ujiki
A Comprehensive Gastro-
Esophageal Database
NorthShore
Ujiki
Per-Oral Endoscopic Myotomy (POEM)
NorthShore
David J. A Prospective Trial of Robotic Thyroid
Winchester and Parathyroid Surgery
NorthShore
Division of Neurosurgery
Division of General Surgery
Singer
ACOSOG Z6051: A Phase III Prospective Randomized Trial
Comparing Laparoscopic-Assisted Resection Versus Open Resection for Rectal Cancer NCI
Denham
Comprehensive Data Registry for NorthShore Bariatric Surgical Services
NorthShore
Prinz
Use of Partial Wave Spectroscopy to NorthShore
Determine Whether Follicular Thyroid Lesions Are Benign or Malignant
Ujiki
A Prospective Randomized Trial NorthShore
Comparing Single-Incision Laparoscopic
Cholecystectomy vs. Standard MultiIncision Laparoscopic Cholecystectomy
Awad*
CLEAR IVH III (Clot Lysis: Evaluated Accelerated Resolution of
Intraventricular Hemorrhage Phase III)
National
Institutes of
Health (NIH)
Awad*
MISTIE: Minimally Invasive Surgery Plus rt-PA for ICH Evacuation
NIH
Ciric
Long-Term Results Following
Transsphenoidal Surgery for Cushing’s Disease—Retrospective Review of
160 Patients
NorthShore
Stadlan
A Prospective, Multi-Center, Double-
Industry
Blind, Randomized, Placebo Controlled
Pivotal Study of Ultrasound Therapy as
Adjunctive Therapy for Increasing Posterolateral Fusion Success Following Single-Level
Posterior Instrumented Lumbar Surgery
continued
* Adjunct faculty with primary appointment at the University of Chicago
Pritzker School of Medicine
2011 Selected Clinical Research Studies
Investigator
Clinical Trial
(continued)
Sponsor
Division of Otolaryngology
Chen
A Randomized Trial of the Management of Pediatric Chronic
Rhinosinusitis With or Without Balloon
Sinuplasty
Investigator
Clinical Trial
Sponsor
Division of Plastic Surgery
NorthShore
Chen
Failed Newborn Hearing Screening: NorthShore
Predicting Eustachian Tube Dysfunction,
2003–2009
Howard
The Prospective Study of Nipple- Sparing Mastectomy: Oncologic and
Reconstructive Outcomes
NorthShore
Sisco
Development and Maintenance of a NorthShore
Comprehensive Breast Reconstruction
Registry at NorthShore University HealthSystem
Gerber
Endoscopic Posterior Cricoid Split and Costal Cartilage Graft Placement in
Children
NorthShore
Warner
Randomized Single-Blind Trial for Pain Reduction in Rhinoplasty Using
Autologous Rib Grafts
NorthShore
Raviv
NorthShore
Bauer
Creation of a Tissue Repository for Biological Samples from Congenital
Nevi and Other Neurocristopathies
NorthShore
Effects of Endoscopic Sinus Surgery for Chronic Sinusitis on Asthma Control
Division of Surgical Oncology
Division of Ophthalmology
Baker
Comparison of Complications and Readmission Rates Following
Laparoscopic and Open Distal
Pancreatectomy Procedures
NorthShore
Baker
Health Related Quality of Life in Surgical and Neoadjuvant Therapy
for Pancreatic Cancer
NorthShore
Talamonti
Analysis of Predictors of Postoperative Morbidity and Long Term
Survival Following Pancreatic Surgery
NorthShore
Talamonti
Clinical Pancreatic Cancer Database and Tissue Bank
NorthShore
Close
A Prospective Case-Crossover Study Industry
to Evaluate the Possible Association
Between the Use of PDE5 Inhibitors and
the Risk of Acute Nonarteritic Anterior
Ischemic Optic Neuropathy (NAION) Macsai
Retrospective Comparison of Surgeon Complication Rates of Vitrectomy
During Cataract Surgery
Sheth/
Maker
A Phase II Evaluation of Topical NSAIDs NIH
in Eyes with Non-Central Involved DME
Sheth
Age-Related Eye Disease Study 2
(AREDS 2)
NorthShore
NIH
David J.
Z1071: Phase II Evaluation SLND and Winchester ACOSOG ALND following Neoadjuvant
Therapy in Stage II/III Breast Cancer
NCI
Yao
Establishment and Maintenance of the NorthShore University HealthSystem
Comprehensive Data Registry for Breast
Surgeries and Breast Tissue Bank
NorthShore
Gupta
A U.S. Phase 2, Randomized Single Industry
Blind, Controlled, Comparative Efficacy
and Safety Study of Topical Fibrocaps™ and
Gelatin Sponge (USP) in Surgical Hemostasis
Yao
Prospective Observational Trial of Breast NorthShore
MRI in Newly Diagnosed Breast Cancers
Gupta
IVC Filter Evaluation of Retrieval Incidence: Temporary vs. Permanent
Yao
Peritumoral Mastectomy Study
Division of Vascular Surgery
NorthShore
NorthShore
Division of Urology
Brendler
A Multi-Phase Study of Active Surveil-
lance for Men with Clinical Stage T1c
or T2a Localized Prostate Cancer
NorthShore
Brendler
Reducing Stress During Active Surveillance
NorthShore
Crawford
Periprostatic Fat as a Promoter of Prostate Cancer Progression
NorthShore
McGuire
3-Dimensional Transrectal Ultrasound NorthShore
for Prostate Cancer Diagnosis
and Surveillance
Dr. Katharine Yao is involved in a number of clinical research
studies for breast cancer, including a prospective observational trial of breast MRI in newly diagnosed disease.
Translational Research
NorthShore has built its reputation on translational research, focusing its scientific
inquiry on the direct improvement of clinical care and patient outcomes.
Under the leadership of Susan Crawford, DO, Director of NorthShore’s Metabolic Core Facility and
Scientific Director of the Center for Molecular Medicine, the Department of Surgery is actively involved
in a variety of important research studies that include three major cancers—breast, pancreatic and
prostate. Our physician-scientists are studying ways to use metabolic profiles to determine prognosis
and guide treatment in patients with certain cancers.
Breast Cancer
MR imaging and metabolic analysis of peri-tumoral fat from
patients with breast cancer or patients with known genetic
risk factors for breast cancer
Investigators: Drs. Katherine Yao, Phillip Fitchev and
Susan Crawford
Summary: Imaging studies are performed in each patient group
to determine whether specific changes can be identified in the fat
surrounding breast tumors, and/or fat in breast tissue from patients
known to have genetic risk factors. Explanted fat tissue is analyzed
by nuclear magnetic resonance (NMR) technology and immunohistochemical stains for anti-angiogenic factor and lipid regulator, pigment
epithelium-derived factor (PEDF), and lipolytic enzyme, adipose triglyceride lipase, in formalin-fixed fat tissue samples. The goal of the
project is to discover novel imaging and metabolic features of peritumoral fat, thus, allowing better patient stratification for therapeutic
management.
Functional studies of BRCA2 in the regulation of mammary
stem cell proliferation and differentiation
Investigators: Drs. Qingshen Gao, Xinping Wang, Chaozhong Zou,
Susan Crawford and Phillip Fitchev
Summary: We found that BRCA2 plays an important role in
mammary stem cell differentiation. We also found that depletion of
BRCA2 in telomerase immortalized human mammary epithelial cells
leads to cells with pluripotent stem cell properties, which are capable
of differentiating into myoepithelial, luminal epithelial cells and many
lineages of mesenchymal cells, including adipocyte, chondrocyte,
Center for Molecular Medicine
NorthShore’s new Center for Molecular Medicine is translating
advanced scientific discoveries at the molecular level into
direct tangible benefits for patients. The program focuses
on the cellular structure of diseases, which enables NorthShore
physicians to offer patients new
noninvasive ways of understanding their medical conditions. It
also provides physicians with new
tools to recognize and treat their
patients with therapies tailored
to their individual molecular profile. Janardan Khandekar, MD,
former Chairman of Medicine
at NorthShore, is the Center’s
Janardan Khandekar, MD
Director, with Susan Crawford,
Director, Center for
DO, serving as the Center’s
Molecular Medicine
Scientific Director.
Susan Crawford, DO
Director, Metabolic
Core Facility and
Scientific Director,
Center for Molecular
Medicine
osteocyte, cardiomyocyte and neurocyte. Importantly, these BRCA2
depleted cells are capable of forming tumors in NOD-SCID mice. Our
novel findings suggest that the main tumor suppressing function of
BRCA2 is likely due to its role in mammary stem cells proliferation and
differentiation.
Crosstalk between the BRCA2 and APC/b-catenin pathways in
mammary stem cells and breast cancer
Investigators: Drs. Qingshen Gao, Chaozhong Zou and Katherine
Goss (University of Chicago)
Summary: The regulation of stem cell behavior is thought to be a
major driver of breast cancer pathogenesis and preliminary studies
from the Gao laboratory indicate that BRCA2 is an important stem
cell regulator. APC (adenomatous polyposis coli) is also a tumor suppressor frequently inactivated in breast and other cancers. Recently,
the Goss lab discovered that APC is required for integrity of the differentiated mammary epithelium in vitro, and, in vivo, its loss sufficient to
promote breast tumorigenesis. Wnt/b-catenin signaling is associated
with stem cells in human breast cancer tissues. We hypothesize that
the APC/b-catenin pathway may mediate BRCA2 regulation of stem
cell differentiation and that disruption of APC and BRCA2 pathways
likely play a synergistic role in breast cancer. To test these hypotheses,
we propose to determine the role of the APC/Wnt pathway in BRCA2mediated regulation of stem cell differentiation and elucidate the functional interaction between the BRCA2 and APC/b-catenin pathways in
breast tumorigenesis.
Pancreatic Cancer
Study of pigment epithelium-derived factor (PEDF) as a
potential therapy for pancreatic cancer and to investigate how
cancer cells utilize lipid-related pathways to fuel their growth
Investigators: Drs. Mark Talamonti, Susan Crawford, Lijun Huang
and Margo Quinn, MS
Summary: PEDF is over-expressed in pancreatic cancer cells and
found to suppress tumor growth and invasion in vitro by altering a
checkpoint kinase that monitors DNA damage. Lipid droplets within
the pancreatic cells are altered when PEDF is expressed. Signaling
pathways are being explored to better understand how PEDF
regulates lipid stores in this tumor.
Study of genetic signatures of pancreatic tumors from
patients with multi-year survival vs. one-year survival
Investigators: Drs. Kamalakar Gulukota, Mark Talamonti,
Robert Marsh and Karen Kaul
Summary: While most cases of pancreatic cancer lead to death
within a year, there are some long-term survivors (more than five
years). We will sequence the exomes of both types of tumors.
Analysis of the sequence will be done to identify the genetic
continued
markers of long-term survival.
Generating pancreatic cancer animal models by targeting
BRCA2 pathway
Investigators: Drs. Qingshen Gao, Chaozhong Zou, Susan Crawford
and Phillip Fitchev
Summary: We are in the process of developing three pancreatic
cancer mouse models by targeting BRCA2, centrobin and DSS1.
Pancreatic tissue specific knockout mice will be generated by
expressing cre recombinase specifically in pancreas. These mice
will be crossed with Kras transgenic mice to evaluate their function
in pancreatic cancer tumorigenesis.
Novel pancreatic cancer susceptibility genes
Investigators: Drs. Qingshen Gao, Wendy S. Rubinstein, Mark
Talamonti, Chaozhong Zou, Vivien Wang, Karen Kaul, Randall E.
Brand (University of Pittsburgh), and David Bentrem (Northwestern
University) and Raj. H. Koneru, MS, and Kristen Vogel, MS
Summary: BRCA2 mutations likely account for the largest percentage of familial pancreatic carcinoma. Components of the BRCA2
pathway are likely direct targets of tumorigenesis and some may
confer pancreatic cancer susceptibility through germline mutation.
We have identified 13 BRCA2 binding proteins, including DSS1,
MAGE-D1 and centrobin that we have published. We have strong
evidence indicating that the genes encoding these 13 BRCA2 binding
proteins are likely pancreatic cancer susceptibility genes. We have
screened for germline mutations for candidate genes encoding these
BRCA2 binding proteins in 276 participants in our Pancreatic Cancer
Family Registry (PCFR). We have identified a number of potential
mutations in the candidate genes which are not present in the 480
control subjects. These findings suggest that these variants are
potential disease-causing mutations. We are now in the process of
determining whether loss of heterozygosity is present in the mutation
carriers’ pancreatic cancer samples. The family members of the
mutation carriers are in the process of being recruited to determine
whether these potential mutations will co-segregate with pancreatic
cancer.
Aging and pancreatic cancer
Investigators: Drs. Qingshen Gao and Chaozhong Zou and
Michael Kamradt, BS
Summary: The risk factors consistently reported for pancreatic
cancer are advanced age and cigarette smoking. In this project,
we proposed to explore the role of aging in pancreatic cancer
tumorigenesis using a mutated lamin gene that causes progeria.
Hutchinson-Gilford progeria syndrome is a rare disorder characterized
by accelerated aging and early death, which is caused by a lamin
mutation (G608G). This mutation results in production of a dominant
negative form of lamin A protein, referred to as progerin. Recent findings indicate that progerin expression also plays a role in normal
aging. We hypothesize that progerin expression likely promotes pancreatic cancer tumorigenesis. We have generated a transgenic mouse
model by crossing progerin transgenic mice with BRCA2 mutant
mice. We will further develop pancreatic tissue specific mutants to
assess the role of progerin in pancreatic cancer tumorigenesis.
Functional studies of centrobin, a component of BRCA2
pathway
Investigators: Drs. Qingshen Gao, Chaozhong Zou and
Radhika Gudi
Summary: We have identified 13 BRCA2 interacting proteins, which
are likely important components of BRCA2 pathway. One of these
BRCA2 binding proteins is a novel daughter centriole protein, centrobin. We are in the process of studying its biological function and
its role in pancreatic and breast cancer tumorigenesis.
Develop a therapeutic approach for pancreatic cancer with
fewer side effects by targeting a critical centrosomal protein,
centrobin
Investigators: Drs. Qingshen Gao, Xinping Wang, Chaozhong Zou
and Radhika Gudi
Summary: The majority of chemotherapeutic drugs target DNA
replication, effectively killing rapidly dividing cells, including cancer cells,
as well as rapidly dividing normal cells in some tissues. Damage to
these normal tissues with rapidly dividing cells, including hair follicles,
intestinal epithelium and bone marrow, leads to common side effects
such as alopecia, diarrhea and hematologic disorders including
anemia. We have recently found that depletion of centrosomal proteins
such as centrobin inhibits centrosome duplication in cancer cells, leading eventually to cell death, while in normal cells, inhibition of centrosome duplication leads to cells with unduplicated centrioles and cell
cycle arrest, but not cell death. Therefore, we hypothesize that inhibition
of centrosome duplication could be a novel therapeutic approach for
pancreatic cancer with fewer side effects. We have indentified a critical
domain of centrobin that is important for its interaction with tubulins
and have established that centrobin-tubulin interaction is required for
centriole elongation and stability. Two critical phosphorylation sites
have also been identified.
Prostate Cancer
Metabolic analysis of peri-prostatic fat surrounding tumorbearing prostates and normal prostates in obese and
non-obese patients
Investigators: Drs. Susan Crawford, Jennifer Doll, Phillip Fitchev
and Charles Brendler
Summary: Peri-prostatic fat from each patient group is analyzed
using NMR technology and various bioassays to discover any unique
metabolites made by peri-prostatic fat in the obese patient group.
Fat-derived metabolites that are discovered to promote tumor cell
proliferation in bioassays have the potential to serve as biomarkers
to predict disease outcome or they can be the target for development
of new therapeutic interventions.
Development of bioadhesive for delivery of stem cells to postsurgical tumor sites to provide immediate anti-tumor therapy
Investigators: Drs. Susan Crawford, Guillermo Ameer and Phillip Fitchev
Summary: We have discovered that stem cells can secrete anti-angiogenic proteins, and we are developing a system in collaboration with
biomedical engineers from Northwestern to embed neural stem cells in
a bioadhesive derived from marine mollusks. This can then be applied
to the bed of a tumor following surgical removal to eradicate microscopic residual cancer cells before they can replicate and metastasize.
Study the pattern of fat infiltration in low- and high-grade
human prostate cancer specimens and the expression of
lipid regulators
Investigators: Drs. Kristian Novakovic, Susan Crawford and
Phillip Fitchev
Summary: Since fat cells are known to secrete tumor-promoting
factors, we are evaluating whether high-grade tumors are associated
with infiltrating fat and whether this fat promotes tumor dedifferentiation
and progression.
Investigate the expression pattern of lipid regulators in prostate
core biopsies in patients enrolled in the active surveillance study
and compare these data to body mass index (BMI) and tumor
progression
Investigators: Drs. Susan Crawford, Phillip Fitchev and Charles Brendler
Summary: Immunohistochemical studies using antibodies directed
against lipolytic mediators are being performed on prostate core
biopsy samples. The staining is scored by two pathologists and will
be compared to BMI.
Selected Honors
Throughout its nine divisions, the skills and expertise of the physicians in the Department
of Surgery have been recognized by a variety of professional organizations and publications.
Those selected honors and the individual physicians recognized are listed here.
National Recognition
The Divisions of Neurosurgery and Urology were recognized
in 2011 by US News & World Report as among the “best
performing” programs nationally.
Castle Connelly Top Doctors United States—Top 1 Percent
John Alexander, MD, Cardiac Surgery
Bruce Bauer, MD, Plastic Surgery
Charles Brendler, MD, Urology
John Howington, MD, Thoracic Surgery
Richard Prinz, MD, Surgical Oncology
Mark Talamonti, MD, Surgical Oncology
Castle Connelly Top Doctors United States—Top 10 Percent
Ermilo Barrera, MD, Surgical Oncology
Michael Blum, MD, Urology
Thomas Keeler, MD, Urology
Marian Macsai, MD, Ophthalmology
Michael McGuire, MD, Urology
Joseph Muldoon, MD, General Surgery
Nancy Schindler, MD, Vascular Surgery
Jose Velasco, MD, General Surgery
David J. Winchester, MD, Surgical Oncology
Who’s Who in the World/America/Medicine and Healthcare
Charles Brendler, MD, Urology
Leonard Cerullo, MD, Neurosurgery
John Howington, MD, Thoracic Surgery
Marian Macsai, MD, Ophthalmology
Mark Talamonti, MD, Surgical Oncology
• John Alexander, MD—President, American College of Chest
Physicians Foundation
• John Howington, MD—Chair, Thoracic Oncology Network,
American College of Chest Physicians
• John Howington, MD—Illinois Governor, American College
of Chest Physicians
• John Howington, MD—Membership Committee, Southern
Thoracic Surgical Association
General Surgery
• Michael Ujiki, MD—Awarded Preceptor of the Year from
Rosalind Franklin University of Medicine and Science • Jose Velasco, MD—Appointed Director of Education,
NorthShore Center for Simulation and Innovation
Neurosurgery
• Gail Rosseau, MD—Appointed Vice President, North America,
World Federation of Neurosurgical Societies Ophthalmology
• Marian Macsai, MD—Awarded Teacher of the Year by
Division of Ophthalmology at the University of Chicago
Pritzker School of Medicine
Surgical Oncology
• Marshall Baker, MD—Best Original Paper by New Member,
Midwest Surgical Association Meeting, 2010
• Katharine Yao, MD—Appointed to Internal Advisory
Committee, University of Chicago Breast Special Program
of Research Excellence (SPORE) Program
• Katharine Yao, MD—Appointed to Executive Committee,
Central Surgical Association
Urology
• Susan Crawford, DO—Currently the Director of Urologic
Research; recently appointed Scientific Director of the
NorthShore Center for Molecular Medicine
Vascular Surgery
• Joseph Caprini, MD—President, American Venous Forum
• Tina Desai, MD—Program Committee, Midwest Vascular
Surgery Society, 2010–2011
• Benjamin Lind, MD—Medical Director, Highland Park Wound
Care Center
• Nancy Schindler, MD—Chairman, Awards Committee,
Association for Surgical Education
Division of Cardiac and Thoracic Surgery
Division Surgeons
Highlights and Accomplishments
After five years of outstanding service as Division Chief, John Alexander, MD, retired as Chief of Cardiac
Surgery and has been succeeded by Paul J. Pearson, MD, PhD, a Mayo Clinic-trained cardiothoracic surgeon and scientist. Dr. Pearson’s overall goal is to make the Division a destination site for cardiac surgery.
Specific Divisional initiatives include focusing on the surgical treatment of heart failure, a multidisciplinary
approach to complex aortic surgery, hybrid surgical approaches for the treatment of atrial fibrillation and
partnering with the Division of Cardiology to establish a regional Heart Valve Institute.
Paul Pearson, MD, PhD
Chief of Cardiac Surgery
New Faculty
• Ki Wan Kim, MD—Dr. Kim completed general surgery residency at the University of Southern California
and a thoracic surgery fellowship at the University of Michigan. His interests include thoracic oncology,
minimally invasive/robotic thoracic surgery, esophageal surgery and mediastinal disease.
Resident in Cardiothoracic Surgery
NorthShore now has a full-time cardiovascular and thoracic resident from the University of Chicago.
John Howington, MD
Chief of Thoracic Surgery
Subhasis Chatterjee, MD
Ki Wan Kim, MD
Clinical Programs
• Perfusion Technology—Introduced the
cardiopulmonary “mini circuit” (Medtronic
Resting Heart System, Minneapolis, Minn.)
that dramatically reduces blood and blood
product utilization for use in all heart operations requiring cardiopulmonary bypass.
NorthShore is the only institution in Illinois
utilizing this advanced new technology.
• Thoracoscopic Heart Surgery—
Performed first totally thoracoscopic
epicardial ablation procedures on the
beating heart. This technology allows us
to treat patients with debilitating cardiac
arrhythmias utilizing telescopes and miniaturized radiofrequency probes.
• Least Invasive Heart Valve Surgery—
Introduced “least invasive” heart surgery
to treat structural heart disease.
Technology allows surgeons to repair
and replace heart valves through small
ports instead of through a conventional
chest incision.
• Lung Cancer Screening—John
Howington, MD, is Co-Director of a multiinstitutional new clinical program using CT
scans to screen 55- to 79-year-old patients
with a smoking history of 30 or more packs
per year.
Dr. John Howington’s expertise includes performing
video-assisted thoracoscopic surgery, or VATS, a
minimally invasive procedure to remove lung tumors.
Clinical Trials
• Partner II Trial—Partnering with Cardiology to evaluate the next-generation Edwards SAPIEN XT
valve for transcatheter treatment of severe symptomatic aortic heart valve stenosis.
• EVEREST II Trial—Partnering with Cardiology in a randomized study of Evalve Inc., Cardiovascular
Valve Repair System (MitraClip®) in the treatment of mitral valve regurgitation.
• EXCEL Trial—Study comparing outcomes of drug-eluting stents to coronary artery bypass surgery
in patients with left main coronary artery disease.
NorthShore Service
• John Howington, MD, Chief of Thoracic Surgery, also serves as Director for Medical Group Quality
for Surgical and Hospital-based specialties.
Division of General Surgery
Division Surgeons
The Division of General Surgery was divided this year
into two Divisions: the Division of General Surgery led
by Ervin (Woody) Denham, MD, and the Division of
Surgical Oncology led by David J. Winchester, MD.
The Division of General Surgery includes the sections
of Colorectal and Minimally Invasive Surgery and is
composed of nine surgeons.
Woody Denham, MD
Division Chief
Stephen Haggerty, MD
John Linn, MD
Barbara Loris, MD
Joseph Muldoon, MD
Marc Singer, MD
James Spitz, MD
Michael Ujiki, MD
Jose Velasco, MD
New Faculty
• John Linn, MD, completed his general surgical
residency at Northwestern University and then a
minimally invasive surgical fellowship at Ohio State
University.
• Stephen Haggerty, MD, and Barbara Loris, MD,
highly regarded general surgeons in Lake County,
have joined the NorthShore Medical Group.
New Facility
The NorthShore Center for Simulation and Innovation
(NCSI) opened at NorthShore Evanston Hospital in
May 2011. The NCSI is a state-of-the-art, 13,000square-foot facility that is used for both minimally
invasive surgical research and education. Under the
leadership of Michael Ujiki, MD, Director of Surgical
Simulation, NCSI has already conducted six training
courses and will be increasingly utilized for the education of attending surgeons, surgical residents, medical
students and other health professionals. Jose Velasco,
MD, Chief of Surgery at NorthShore Skokie Hospital,
has been named Director of Education for this
new facility.
Clinical Programs
• Minimally Invasive Surgery (MIS)—Under the
leadership of Michael Ujiki, MD, several new surgical
procedures have been introduced including esophageal peroral endoscopic myotomy to treat achalasia
and restorative endolumenal surgery for morbidly
obese patients.
Clinical Programs (continued)
• Colorectal Surgery—Under the leadership of
Joseph Muldoon, MD, NorthShore has become
a regional leader in innovative new surgical procedures, including sacral nerve stimulation for
fecal incontinence.
Clinical Trials
The Division has multiple ongoing clinical trials
including:
• Outcomes of Single-Port Versus Multiple-Port
Cholecystectomy
• Efficacy of Pain Pumps in Abdominal Wall
Hernia Repair
• Evaluation of Compression Colorectal
Anastomosis Ring
• Efficacy of Bioabsorbable Staples in Intestinal
Anastomoses
• Multicenter Study of Bio-Fistula Plus In-Anal
Fistula Repair
Selected Visiting Professorships
• Joseph Muldoon, MD—“Minimally Invasive
Surgery in Colon and Rectal Cancer.” Presented
at NorthShore Continuing Medical Educational
Conference, Northfield, Ill., March 2011.
• Marc Singer, MD—“Anal Fistulas: Have We
Given Up on Glue?” and “Beyond Snare
Polypectomy.” Presented at American Society
of Colon and Rectal Surgeons Annual Meeting,
Vancouver, Canada, May 2011.
• Michael Ujiki, MD—Multiple Presentations. Society of American Gastrointestinal and
Endoscopic Surgeons, Washington, DC,
April 2010.
• Jose Velasco, MD—Laparoscopic Instructor;
97th Annual Clinical Congress of the American
College of Surgeons, San Francisco, Calif.,
October 2011.
The NorthShore Center for Simulation and
Innovation (NCSI) opened in May 2011 at
Evanston Hospital. NCSI is designed specifically for multispecialty, multidisciplinary
surgical simulation. It is a leading resource
for surgeons both to train in established
minimally invasive techniques and to develop
and test new methods and procedures. NCSI
received accreditation as a comprehensive
Level I program from the American College
of Surgeons (ACS) Education Institute.
Division of Neurosurgery
Division Surgeons
New Department and Departmental Chairman
Neurosurgery this year became an independent
Department and successfully recruited its first
Chairman, Julian Bailes, MD, from the West
Virginia University School of Medicine where
he had been Professor and Chairman of
Neurosurgery. Dr. Bailes is internationally
recognized for his expertise in the management
of brain trauma.
Julian Bailes, MD
Department Chair
James Brown, MD
Leonard Cerullo, MD
Ivan Ciric, MD
(retired 2011)
Geoffrey Dixon, MD
Egon Doppenberg, MD
Ted Eller, MD
Hamad Farhat, MD
Dean Karahalios, MD
Edward Mkrdichian, MD
Adebukola Onibokun, MD
Gail Rosseau, MD
Noam Stadlan, MD
Recruitment of CINN Neurosurgeons and
Neuroresearch Physicians to NorthShore
The Chicago Institute of Neurosurgery and
Neuroresearch (CINN) was successfully recruited
and integrated into the NorthShore Division
(now Department) of Neurosurgery.
Establishment of NorthShore
Neurological Institute (NNI)
In collaboration with the Department of Neurology,
this new Institute will occupy the second floor of
the John and Carol Walter Ambulatory Care Center
at Glenbrook Hospital, which is currently under
construction and scheduled to open in March
2012.
Endowed Departmental Chair
The Ivan S. Ciric Chair of Neurological Surgery
was established. Julian Bailes, MD, the new
Professor and Chairman of Neurosurgery, was
endowed with the Arlene and Marshall Bennett
and Joseph A. Tarkington, MD, Chair of
Neurosurgery.
Collaborations
• Orthopedics: Combined Neurosurgery—
Orthopedic Spine Conference initiated
• Neurology: Comprehensive stroke, normal
pressure hydrocephalus, epilepsy, trigeminal
neuralgia and deep brain stimulation programs
• Otolaryngology: Skull-base collaboration for
pituitary tumors and other tumors approached
via the temporal bone
The Division of Neurosurgery
is composed of neurosurgeons who are nationally
and internationally regarded
in their field, including
Dr. Gail Rosseau and
Dr. Ivan Ciric. Dr. Ciric
retired from NorthShore
in 2011 after 44 years.
Creation of Academic Day
Held the third Friday of each month and devoted to
resident teaching, presentations and visiting professors
have included:
• Richard Byrne, MD, Professor and Chairman of
Neurosurgery, Rush University School of Medicine
• John Liu, MD, Associate Professor of Neurosurgery,
Northwestern University
• Michael Lawton, MD, Professor of Neurosurgery,
University of California, San Francisco
• Josh Medow, MD, Assistant Professor of
Neurosurgery, University of Wisconsin
• Marc Simard, MD, Professor of Neurosurgery,
University of Maryland
• Julian Bailes, MD—Goldwater Lecturer, Barrow
Neurological Institute, Phoenix, Ariz., February 2011
• Julian Bailes, MD—Visiting Professor, Department
of Neurosurgery, Stanford University Medical Center,
Stanford, Calif., March 2011
• Julian Bailes, MD—National Neurotrauma
Symposium, Fort Lauderdale, Fla., July 2011 • Julian Bailes, MD—Honored Guest, Georgia
Neurosurgical Society, Atlanta, Ga., December 2011
• Ivan Ciric, MD—University of Novi Sad, Novi Sad,
Serbia, July 2010 and June 2011
• Ivan Ciric, MD—International Neuroscience Institute
Congress, Hannover, Germany, July 2010
• Ivan Ciric, MD—University of Kragujevac,
Kragujevac, Serbia, June 2011
• Dean Karaholios, MD—Surgical Experimentation
Program Bio-Skills Laboratory, Florence, Italy,
October 2010
• Gail Rosseau, MD—Gurdjain-Thomas Visiting
Professor, International Neurosurgical Programs in
Head and Spine Injury Prevention, Wayne State
University, Detroit, Mich., January 2011
Educational Courses Taught
• Leonard Cerullo, MD—Evidence-Based Treatment of
Common Spine Conditions, NorthShore University
HealthSystem CME course, June 2011
Division of Ophthalmology
Division Surgeons
New and Expanded Offices
• Vernon Hills—New office on Milwaukee Avenue
staffed by Tony Pira, MD.
• Evanston Office—Expanded into new space at
1000 Central Street; anticipated that even larger
space will be required in a few years.
Marian Macsai, MD
Division Chief
Troy Close, MD
Joshua Herz, MD
Ann Laurenzi-Jones, OD
Manvi Maker, MD
Tony Pira, MD
Peter Rabiah, MD
Veeral Sheth, MD
New Faculty
• Manvi Maker, MD—Dr. Maker was recruited
from New York University and currently sees
patients at Glenbrook and Evanston Hospital
locations. He specializes in retinal diseases,
including diabetic retinopathy.
• Tony Pira, MD—Dr. Pira was recruited from
Boston University and sees patients at Vernon
Hills and Glenbrook Hospital locations. He specializes in family and geriatric ophthalmology.
Recognition
• Marian Macsai, MD—Chair, Eye Bank
Association of America
• Marian Macsai, MD—Committee on
Membership, American Ophthalmological
Society
• Manvi P. Maker, MD—Associate Program
Director, Ophthalmology Residency, University
of Chicago
International Service
• Marian Macsai, MD—Traveled to Vietnam
teaching cataract surgery to Vietnamese
ophthalmologists.
• Marian Macsai, MD—As Chair of the Eye Bank
Association of America, worked in Sri Lanka
helping to form an association of eye banks in
Asia and is also working to help form a global
alliance of eye bank associations.
• Marian Macsai, MD—Attended two meetings
sponsored by the World Health Organization
regarding vigilance and surveillance of disease
transmission through organ transplantation;
Dr. Macsai is the representative for ocular
tissue.
Clinical Trials
• Troy Close, MD—Relationship between PDE5
inhibitors and non-arteritic anterior ischemic optic
neuropathy
• Marian Macsai, MD—Implanted Accommodative
Intraocular Lenses; Phase II trial for Abbott Medical
Optics
• Marian Macsai, MD, and Mira Shiloach, MS—
Working with University of Chicago medical students
to analyze differences in surgical techniques in
cataract surgery and how these affect outcomes
• Veeral Sheth, MD, and Manvi Maker, MD—Accepted
to Diabetic Retinopathy Clinical Research Network,
national network of investigators sponsored by
National Eye Institute
• Veeral Sheth, MD—Use of intravitreal vascular
endothelial growth factor (VEGF) in treatment of
age-related macular degeneration
• Veeral Sheth, MD—Vitamin supplementation in
age-related eye disease (AREDS II); NIH funded
multicenter trial
Grants
• Veeral Sheth, MD, PI—“Comparison of Vitreal pH
Between Diabetic and Non-Diabetic Patients: A Pilot
Study,” NorthShore Research Institute Pilot Grant
• Marian Macsai, MD—“50 Years of Cornea Vigilance,”
Eye Bank Association of America. Presented at
World Health Organization—Project NOTIFY,
Bologna, Italy, February 2011 • Veeral Sheth, MD—Invited Lecturer, Combined
Meeting of the Asia-Pacific Vitreo-Retina Society
and Vitreoretinal Society of India, Hyderabad, India,
December 2011
Forecast for 2012
• Open an optical shop at Glenbrook Hospital • Integrate Ophthalmology imaging into NorthShore’s
Electronic Medical Record (EMR) system
• Initiate multi-institutional clinical trial to better
understand the effects of pH on the diabetic retina
Dr. Marian Macsai, Chief of
the Division of Ophthalmology,
is pictured examining patient
Charles Woods, whom she
treated for a life-changing
corneal transplant surgery.
Under Dr. Macsai’s leadership,
the Division expanded into new
office space in Evanston and
established a new office in
Vernon Hills.
Division of Otolaryngology
Division Surgeons
Mark Gerber, MD, has succeeded Barry Wenig, MD, as Chief of Otolaryngology. Dr. Gerber completed
residency and fellowship training in pediatric otolaryngology and maxillofacial surgery at Children’s Hospital
Medical Center in Cincinnati, and, after several years in practice in Atlanta joined NorthShore University
HealthSystem in 1999.
Mark Gerber, MD
Division Chief
Mihir Bhayani, MD
Judy Chen, MD
Joseph Raviv, MD
Ilana Seligman, MD
Michael Shinners, MD
New Faculty
• Mihir Bhayani, MD—Dr. Bhayani completed residency at the University of Chicago and then a two-year
oncology fellowship at M.D. Anderson Cancer Center. He is the only oncology fellowship-trained head
and neck cancer surgeon in the northern suburbs of Chicago.
Clinical Programs
• Rhinology and Anterior Skull Base Program—Established in 2007 by Joseph Raviv, MD, this is the first
center in the northern Chicagoland area to offer comprehensive medical and surgical treatment of chronic
sinusitis by a fellowship-trained otolaryngologist. Providing more than 3,500 patient visits per year, the
NorthShore Sinus Center offers advanced care, including minimally invasive and computer-assisted surgery, for patients with chronic sinusitis, nasal polyposis, fungal sinusitis, nasal obstruction and tumors of
the nasal cavity and anterior skull base. Approach to these disorders is multidisciplinary, incorporating the
expertise of Neurosurgery, Allergy/Immunology, Pulmonology and Maxillofacial Surgery.
• Neurotology—Led by Michael Shinners, MD, the NorthShore neurotology program utilizes a comprehensive approach to diagnose and manage the full spectrum of ear diseases, including the medical and surgical management of Meniere’s disease, chronic ear infections, cholesteatoma and hearing loss including
cochlear implant team services for infants, children and adults. Audiometric services range from initial
evaluation of children who have failed their newborn hearing screening to hearing aid fitting and complex
cochlear implant programming. Our team collaborates with both Neurosurgery and Plastic Surgery to
manage complex lateral skull base tumors such as acoustic neuromas and meningiomas, as well as
congenital abnormalities that include congenital outer ear abnormalities and conductive hearing loss.
• Pediatric Otolaryngology—Head and Neck Surgery section includes three fellowship-trained specialists
who provide more than 12,000 outpatient visits and 1,700 surgical procedures per year. NorthShore
Pediatric Airway, Voice and Resonance Clinic, led by Mark Gerber, MD, is one of the only programs
in the Chicago area that provides comprehensive evaluations for children with congenital or acquired
airway, voice, resonance and swallowing problems. Combining multispecialty child-focused resources
allows for a detailed diagnostic analysis, as well as directed management with a wide array of both
medical and surgical options. These options include cleft palate repair, sphincter pharyngoplasty
and laryngeal reconstruction using minimally invasive endoscopic techniques.
Recent Grants Awarded
• Mihir Bhayani, MD—Enhancing Radio Sensitivity Through Inhibition of STAT3 in Head and Neck
Squamous Cell Carcinoma; American Head and Neck Society CORE Grant Program, $10,000
Selected Visiting Professorships/Invited Lectureships
• Mark Gerber, MD—Fiber Optic Endoscopic Evaluation of Swallowing in Children. Presented at Pediatric
Dysphagia Course, Rehabilitation Institute of Chicago, Chicago, Ill., July 2010
• Joseph Raviv, MD—Contemporary Management of Chronic Sinusitis. Presented at Otolaryngology
Grand Rounds, University of Chicago, Chicago, Ill., March 2011
Selected Educational Courses Taught
• Joseph Raviv, MD—NorthShore University HealthSystem Chicago Rhinoplasty Symposium, Chicago, Ill.,
May 2010 and May 2011
• Michael Shinners, MD—Temporal Bone Dissection Course for University of Chicago Otolaryngology
residents, Chicago, Ill., August 2010
Division of Plastic Surgery
Division Surgeons
Bruce Bauer, MD, succeeded Karol Gutowski, MD, as Division Chief of Plastic Surgery. Dr. Bauer was
previously the Chief of Pediatric Plastic Surgery at Children’s Memorial Hospital. He is internationally
recognized for his expertise in pediatric plastic surgery, with special expertise in the treatment of large and
giant congenital nevi, correction of congenital and acquired deformities of the ear and tissue expansion in
children for a full range of congenital and acquired deformities in all body regions.
New Division Members
• Veronica Rundell, PhD, joined the Division as Clinical Research Associate. Bruce Bauer, MD
Division Chief
Michael Howard, MD
Mark Sisco, MD
Jeremy Warner, MD
• D. Brooks Johnson, MD, joined the Division as Research Associate. Clinical Programs
• Hair Transplantation—Jeremy Warner, MD, is investigating a new micro grafting technique in hair
transplantation.
• Migraine Surgery Clinic—Michael Howard, MD, is investigating botox injections and surgical techniques
for treatment of selected migraine headache cases.
Clinical Trials
• Giant Nevi and Neurocutaneous Melanocytosis—Bruce Bauer, MD, is collaborating with the University
of Pittsburg Children’s Hospital to establish a tissue bank to study the embryologic development and
neural sequelae of giant nevi.
• Otoplasty—Bruce Bauer, MD, is leading a new IRB-approved study entitled “The Impact of Otoplasty on
Psychological Wellness.”
• Breast Reconstruction
– Michael Howard, MD, is leading a study of long-term complications of dermal matrix implants in breast
reconstruction. He is also leading our nipple-sparing mastectomy study and long-term surveillance
study of silicone breast implants.
– Mark Sisco, MD, has developed a prospective breast reconstruction database that will follow patients
for 10 years postoperatively to assess satisfaction and emotional wellness. He is also conducting a
retrospective chart review investigating preoperative predictors of postmastectomy radiation therapy.
• Rhinoplasty Pain Reduction—Jeremy Warner, MD, is investigating which of two types of rib graft results
in lower postoperative pain following rhinoplasty.
Selected Visiting Professorships/Invited Lectureships
• Bruce Bauer, MD—Co-Chairman, Aesthetic Facial Reconstruction in Adults and Children Symposium,
Tucson, Ariz., February 2010
• Bruce Bauer, MD—Plastic Surgery Residents’ Day, University of Alberta, Edmonton, Alberta, Canada,
April 2010
• Bruce Bauer, MD—“The Role of Tissue Expansion in Treatment of Large and Giant Nevi,” 2011
International Expert Meeting on Large Congenital Melanocytic Nevi and Neurocutaneous Melanocytosis
Nevus Outreach and Department of Dermatology, University of Tübingen, Germany, May 2011
• Michael A. Howard, MD—“Incorporating Nipple-Sparing Mastectomy (NSM) Into Your Practice,”
American Society of Plastic Surgeons Instructional Course, Toronto, Canada, October 2010 and
September 2011
• Jeremy Warner, MD—“The Crooked Nose,” University of Wisconsin, Madison, Wis., June 2010 Educational Courses Taught
• Jeremy Warner, MD—Director, Chicago Rhinoplasty Symposium, March 2010 and March 2011 Future Goals
• Expand practices of three junior plastic surgeons • Recruit additional pediatric plastic surgeon
• Re-establish pediatric plastic surgery teaching relationship with another Chicago academic institution Department of Surgery 2011 Annual Report 15
Division of Surgical Oncology
Division Surgeons
The newly established Division of Surgical
Oncology is led by David J. Winchester, MD, who
is internationally recognized for his expertise in
breast and endocrine cancers.
David J. Winchester, MD
Division Chief
Marshall Baker, MD
New Faculty
Tricia Moo-Young, MD—Completed residency
training at Washington University in St. Louis and a
surgical endocrinology fellowship at Rush University
Medical Center. With her recruitment, the Division
now has eight faculty members and provides specialized care for patients with breast, thyroid, melanoma,
sarcoma, esophageal, gastric, hepatobiliary and
pancreatic cancers.
Ermilo Barrera, MD
Tricia Moo-Young, MD
Richard Prinz, MD
Mark Talamonti, MD
David P. Winchester, MD
Katharine Yao, MD
Clinical Programs
• Breast Cancer
– Katharine Yao, MD, directs our breast surgical
program, and NorthShore continues to lead
Illinois as a top care provider for newly diagnosed breast cancer patients. NorthShore has
been designated as one of two National Cancer
Database Breast Participant Use File Alpha Sites,
providing direct access to the nation’s largest
breast cancer database.
– Under the leadership of David P. Winchester, MD,
our previous Chairman of Surgery, breast cancer
services have been extended to Lake County.
• Endocrine Cancers—Under the leadership
of Richard Prinz, MD, the endocrine surgery program now offers new minimally
invasive surgical procedures, including
retroperitoneal adrenalectomy, robotic
thyroidectomy and minimally invasive
parathyroid surgery.
Selected Visiting Professorships/Invited
Lectureships
• Richard Prinz, MD—“Differentiated Thyroid
Cancer: What’s New?” Presented at Surgery
Grand Rounds, Cedars-Sinai Medical Center,
Los Angeles, Calif., March 24, 2010
• Mark Talamonti, MD—Pancreatic Cancer
Action Network Advocacy Days, Arlington, Va.,
June 12–14, 2011
• David J. Winchester, MD—“Treatment of Soft
Tissue Sarcomas.” Presented at Annual Congress
of the Chilean Chapter of the American College of
Surgeons, Santiago, Chile, May 8, 2010
• David P. Winchester, MD—“The National
Accreditation Program for Breast Centers: The
Road to Quality Improvement.” Presented at the
International Forum for Cancer Care Quality and
Accreditation, Taipei, Taiwan, Sept. 17, 2011
Recent Grants Awarded
Katharine Yao, MD—“Peritumoral fat as a promoter
of breast cancer progression.” Breast and Ovarian
Cancer Research Award, NorthShore University
HealthSystem, $50,000
Katharine Yao, MD—“MicroRNAs as novel biomarkers in breast cancer.” Breast and Ovarian Cancer
Research Award, NorthShore University
HealthSystem, $50,000
• Gastroesophageal, Hepatobiliary and
Pancreatic Cancers—Mark Talamonti,
MD, and Marshall Baker, MD, provide
nationally acclaimed care, and their
expertise includes both open and
laparoscopic surgery, addressing
complex problems such as portal vein
reconstruction and splenic preservation.
A comprehensive clinical research database has been established resulting in
multiple national presentations and
peer-reviewed publications.
• Other Surgical Programs—The Division
also specializes in the treatment of
advanced melanomas, sarcomas and
multidisciplinary care that includes limbsparing surgery in patients with otherwise
unresectable disease.
Drs. David J. Winchester (left), Tricia Moo-Young and
Richard Prinz provide specialized surgical expertise for
patients with endocrine cancers and related conditions.
Division of Urology
Division Surgeons
Michael McGuire, MD
Division Chief
Jeffrey Albaugh, PhD
Michael Blum, MD
Peter Colegrove, MD
Thomas Keeler, MD
Amanda Macejko, MD
Kristian Novakovic, MD
Sangtae Park, MD
John and Carol Walter Center
for Urological Health Established
The Division of Urology recently received a
$5 million gift from Mr. and Mrs. John Walter to
establish The John and Carol Walter Center for
Urological Health and also a second $5 million
gift from Mr. and Mrs. Donald Rappeport, which
will provide additional funding for the clinical and
scientific programs associated with this Center.
This 6,000-square-foot facility will be located in the
new John and Carol Walter Ambulatory Care Center
currently under construction at NorthShore Glenbrook
Hospital and scheduled to open in March 2012. The
Center will provide comprehensive multidisciplinary
care to men and women with urological cancers and
other urologic diseases.
New Division Chief
After several years of outstanding service, Thomas
Keeler, MD, stepped down as Chief of the Division of
Urology and was succeeded by Michael McGuire, MD.
Dr. McGuire completed his urological residency at
Northwestern and a urological oncology fellowship
at Memorial Sloan-Kettering Cancer Center prior to
joining NorthShore in 2009.
New Faculty
• Jeffrey Albaugh, PhD—Recruited from
Northwestern Memorial Hospital in March 2011 to
be Director of our new Sexual Health Clinic.
• Kristian Novakovic, MD—Recruited from University
of Louisville in September 2010 to be Director of
Urological Oncology.
• Sangtae Park, MD—Recruited from University
of Chicago in October 2010 to be Director of
Minimally Invasive and Robotic Urologic Surgery.
Clinical Programs
• Active Surveillance—NorthShore has the only IRBapproved prostate cancer active surveillance clinical
trial in the region, and NorthShore recently became
the coordinating center for all 15 NCI-sponsored
active surveillance programs across the U.S.
• Quality of Life and Clinical Outcomes—NorthShore
has the only IRB-approved clinical trial in the region
examining quality of life and the impact of stress
reduction on men and their spouses enrolled in
our active surveillance study.
• IMPACT Study—NorthShore is participating in an
international trial investigating the impact of BRCA
mutations on prostate cancer risk and progression
in men with a family history of BRCA-1 or BRCA-2
positive breast cancer. NorthShore is the top recruiting site in the U.S. and sixth overall internationally.
Research Programs
• Relationship of Obesity to Cancer Risk and
Progression—The laboratory of Susan Crawford,
DO, continues to investigate the mechanisms by
which obesity promotes prostate cancer risk and
progression. Dr. Crawford was recently awarded a
grant from the Prostate Cancer Foundation to investigate the role of periprostatic fat in prostate cancer
progression.
• Neural Stem Cell Bio Adhesive Therapy—
Dr. Crawford and her team are also developing a
novel cancer treatment that uses neural stem cells
embedded in a bio adhesive derived from marine
mollusks to eradicate residual cancer cells following
surgical removal of a cancer.
• Molecular Diagnostics—Karen Kaul, MD, PhD,
Director of Molecular Pathology, and her colleagues
are investigating new biomarkers such as urinary
PCA3 to both diagnose and determine prognosis in
prostate cancer.
In 2011 NorthShore received a
$5 million gift from John and Carol
Walter to establish a comprehensive,
state-of-the-art destination center
for urologic care and advanced
research. The John and Carol Walter
Center for Urological Health will be
located in the new John and Carol
Walter Ambulatory Care Center
(ACC) at Glenbrook Hospital scheduled to open in 2012. The Division
also received a second $5 million gift
from Mr. and Mrs. Donald Rappeport,
which will provide additional funding
for the clinical and scientific programs associated with this Center.
Division of Vascular Surgery
Division Surgeons
NavYash Gupta, MD
Division Chief
Joseph Caprini, MD
Tina Desai, MD
Benjamin Lind, MD
Omar Morcos, MD
Nancy Schindler, MD
New Division Chief
NavYash Gupta, MD, continued to
build the Division of Vascular Surgery
since becoming Division Chief in 2009.
Dr. Gupta completed surgical residency
at St. Louis University Hospital and then
a vascular surgery fellowship at the
University of Chicago. Prior to joining
NorthShore, Dr. Gupta was a member
of the surgical faculty at the University
of Pittsburgh for nine years. His special
interests include minimally invasive
endovascular surgery for thoracic
and aortic aneurysms, carotid artery
occlusive disease, peripheral vascular
disease and hemodialysis access.
New Faculty
• Tina Desai, MD—Dr. Desai comDr. Omar Morcos (from left), Dr. Tina Desai and Dr. Benjamin
pleted her surgical residency and
Lind (not pictured) were recruited in 2011 to the Division of
vascular surgery fellowship at the
Vascular Surgery under the leadership of Dr. NavYash Gupta
University of Chicago in 1999. She
(pictured right).
served on the surgical faculty at the
University of Chicago as Assistant
Professor of Surgery and Director of
• Vascular laboratory services have been expanded
the Endovascular Service for 10 years. Her special
and standardized at all four NorthShore hospitals
interests include endovascular surgery and surgical
as well as in the main outpatient office in Skokie.
treatment of abdominal and thoracic aortic pathology, carotid artery occlusive disease, peripheral
Clinical Research
vascular disease and hemodialysis access.
The Division of Vascular Surgery has been actively
• Benjamin Lind, MD—Dr. Lind completed his surgiinvolved in various clinical research projects, including:
cal residency and vascular surgery fellowship at
– Carotid stenting (CHOICE) trial in collaboration
Rush University Medical Center. His special interwith the Division of Cardiology
ests include limb salvage and minimally invasive
vascular reconstruction. Dr. Lind also serves as
– Magnetic resonance imaging (MRI) for evaluathe Medical Director of the Wound Care Center
tion of carotid artery and peripheral vascular
at NorthShore Highland Park Hospital.
occlusive disease, in collaboration with the
• Omar Morcos, MD—Dr. Morcos completed his
surgical fellowship at Mt. Sinai Medical Center
following his residency at the University of Illinois
at Chicago Medical Center.
Clinical Growth
The Division now includes six vascular surgeons
providing comprehensive vascular surgery services
at all four hospitals in the NorthShore area, including
minimally invasive endovascular surgery.
New Facilities
• New endovascular surgical suite opened in the
operating room at Evanston Hospital.
• Division of Vascular Surgery now leads the Wound
Care Center at Highland Park Hospital, allowing
us to provide advanced care of wounds and vascular injuries and offering patients increased access
to a multidisciplinary team for care and treatment
options, including hyperbaric oxygen therapy.
Department of Radiology
– Evaluation of factors that contribute to disparities in vascular surgery care in various ethnically
and economically diverse populations in the
greater Chicago area
Selected Visiting Professorships/
Invited Lectureships
• Joseph Caprini, MD—Served as Visiting Professor/
Invited Lecturer on 50 occasions, including in
Great Britain, France, Belgium, Portugal, India
and Japan
• Tina Desai, MD—“Device Manufacturers and
Medicine: The Fine Line Between Collaboration
and Conflict of Interest.” Presented at Chicago
Surgical Society, Chicago, Ill., Nov. 4, 2010
• NavYash Gupta, MD—“Whom I Would Choose for
Surgical Treatment of Abdominal Aortic Aneurysm.”
Presented at Society for Cardiovascular
Angiography and Interventions, 33rd Annual
Scientific Meeting, San Diego, Calif., May 6, 2010
Philanthropy
Fiscal year 2010–2011 has witnessed extraordinary generosity from donors whose gifts have
empowered the physician-scientists of our
Department to take new leadership roles in
advanced research and surgical healthcare.
Responding to the priorities set out last year in the Department’s
first Philanthropic Strategic Plan—with its focuses on Leadership
and Program Development, Translational Research, Clinical Trials
and Outcomes Research and Surgical Education—these leadership gifts attest to the skill, compassion and care of our surgeons
as well as to their commitment to partnering with grateful patients
to provide innovative, research-driven care.
The Department’s program in Minimally Invasive Surgery (MIS)
also continues to benefit from the generous multiyear funding
provided through The Grainger Foundation, which has sustained
the development and refinement of new MIS and Natural Orifice
Translumenal Endoscopic Surgery (NOTES) procedures under the
direction of Michael Ujiki, MD. These funds have also underwritten
the purchase of new simulation equipment and supported key
staffing for the Department’s programs based in the NorthShore
Center for Simulation and Innovation (NCSI). Grainger Foundation
funds have also enhanced video conference and software capacity
at NorthShore Skokie Hospital’s simulation laboratory, founded and
directed by Jose Velasco, MD.
Sustaining gifts from the Blum Kovler Foundation and the
Richard and Martha Melman Foundation have continued to
strengthen our metabolomics research that Susan Crawford, DO,
and her team are conducting through the John and Carol Walter
Center for Urological Health.
When it joined NorthShore last year to become part of the
NorthShore Neurological Institute (NNI), the Chicago Institute of
Neurosurgery and Neuroresearch (CINN) generously transferred
the assets of its own foundation to NNI, ensuring that its tradition
of clinical excellence supported by its grateful patients will be
continued here.
We also offer our continued gratitude to our devoted donors,
the Ronald L. Chez Family and Richard Melman Family, founders
of the Department’s Chair of Prostate Cancer, a gift that has
brought prestige and attracted other philanthropic support to
our programs.
These foundational gifts crown a long process of planning
and education that we have undertaken to help our patients
understand the dramatic impact they can have on improving
the quality of care we offer. A wide range of unrestricted gifts
to surgery programs, with many directed to the John and Carol
Walter Center for Urological Health, have also added much-needed
support to other research projects. These generous donations
help drive a new array of cutting-edge programs and services in
urologic health and support the development of new therapies
in minimally invasive surgery. From affording insights into molecular
medicine to supporting vital clinical trials, patient philanthropy has
played an increasingly important role for our Department in an
environment where both clinical revenues and government funding
have steadily declined.
Lead Donors 2010–2011
Our lead donors listed below and the more than 100 others
who have joined them have helped us advance our strategic
agenda in patient care, surgical technology, medical education, clinical trials and translational research. To these caring
donors, and to all who have chosen to help our Department
make such important strides, we offer our sincerest gratitude.
Mr. and Mrs. John R. Walter
Mr. and Mrs. Donald L. Rappeport
Mr. Roy Carlson
Blum Kovler Foundation and
Mr. and Mrs. Jonathan Kovler
Mr. Ronald L. Chez
Richard and Martha Melman Foundation
and Mr. and Mrs. Richard Melman
Mr. and Mrs. Mark Spitz
The CINN Foundation
Dr. and Mrs. Joseph Golbus
Lanx Inc.
Mr. and Mrs. Barry S. Alberts
Mr. and Mrs. Warren L. Batts
Dr. and Mrs. Charles B. Brendler
Mr. and Mrs. Matthew S. Dominski
Mr. and Mrs. Lawrence F. Levy
Mr. and Mrs. Robert Schuberth
Mr. and Mrs. William J. White
Dr. and Mrs. Richard A. Prinz
Synthes USA HQ, Inc.
Mr. and Mrs. A. Beecher Abeles
Mr. James E. Deignan
The outstanding benevolence of John and Carol Walter
has launched the new John and Carol Walter Center for
Urological Health at Glenbrook Hospital. Mr. and Mrs. Walter
are pictured here with Michael McGuire, MD, left, and Charles
Brendler, MD, right, Co-Directors of the new center. Their
$5 million gift has, in turn, inspired a similarly generous gift from
Donald and Joan Rappeport, who recently made a $5 million
gift in support of the urologic health programs to be housed
in the John and Carol Walter Center for Urological Health.
These are truly transformational gifts that enable us to launch
a comprehensive set of urologic health programs to meet the
needs of many current and future patients.
2011 Peer-Reviewed Publications and Book Chapters
Howington JA, Gunnarsson C, Maddaus MA, McKenna RJ,
Meyers BF, Miller D, Moore M, Rizzo JA, Swanson S. In-hospital
clinical and economic consequences of pulmonary wedge resections for cancer using video-assisted thoracoscopic techniques vs.
traditional open resections: a retrospective database analysis.
Chest. 2011 Jul 21. [Epub ahead of print]
Starnes SL, Reed MF, Meyer CA, Shipley RT, Jazieh AR, Pina EM,
Redmond K, Huffman LC, Pandalai PK, Howington JA. Can lung
cancer screening by computed tomography be effective in areas
with endemic histoplasmosis? J Thorac Cardiovasc Surg. 2011
Mar;141(3):688-93. Epub 2010 Oct 8.
General Surgery
Singer M, Ehrenpreis ED, Avital S. Anal and Rectal Diseases.
New York, NY: Springer; 2012. (In press)
Singer, M. Hemorrhoids. In: Beck, DE, Roberst PL, Saclarides TJ,
Senagore, AJ, Stamos MJ, Wexner SD, eds. The ASCRS
Textbook of Colon and Rectal Surgery. 2nd ed., New York, NY:
Springer; 2011:175-203.
Gafni-Kane A, Goldberg RP, Spitz JS, Sand PK. Extrasphincteric
perianal fistulae after sacrospinous fixation for apical prolapse.
Obstet Gynecol. 2011 Feb;117(2 Pt 2):438-40.
Bello B, Ujiki MB. Minimally invasive approaches to small bowel
pathology. In: Murayama K, Chand B, eds. Evidence-Based
Approach to Minimally Invasive Surgery; CineMed Publishing.
(In press)
Durham JR, Velasco JM, Krishnamurthy VD, Hieken TJ.
Principles of ultrasound and ablative therapy. In: Velasco J, Bines
SD, Deziel DJ, McCarthy WJ, Millikan JD, Prinz RA, Saclarides
TJ, eds. Rush University Medical Center Review of Surgery. 5th
ed. Philadelphia, PA: Saunders/Elsevier; 2011:539-545.
Fusco C, Velasco JM. Critical care. In: Velasco J, Bines SD,
Deziel DJ, McCarthy WJ, Millikan JD, Prinz RA, Saclarides TJ,
eds. Rush University Medical Center Review of Surgery. 5th ed.
Philadelphia, PA: Saunders/Elsevier; 2011:123-144.
Velasco JM, Jacobs CE. Nutrition, metabolism, and fluid and
electrolytes. In: Velasco J, Bines SD, Deziel DJ, McCarthy WJ,
Millikan JD, Prinz RA, Saclarides TJ, eds. Rush University Medical
Center Review of Surgery. 5th ed. Philadelphia, PA: Saunders/
Elsevier; 2011:29-58.
Ough M, Velasco JM, Hieken TJ. A comparative analysis of core
needle biopsy and final excision for breast cancer: histology and
marker expression. Am J Surg. 2011 May; 201:692-4. Epub 2010
Sep 18.
Velasco JM, Bines SD, Deziel DJ, McCarthy WJ, Millikan JD,
Prinz RA, Saclarides TJ, eds. Rush University Medical Center
Review of Surgery. 5th ed. Philadelphia, PA: Saunders/Elsevier;
2011.
Velasco, JM, Butsch J. Perioperative care. In: Velasco JM, Bines
SD, Deziel DJ, McCarthy WJ, Millikan JD, Prinz RA, Saclarides
Wool N, Velasco JM. Hernia. In: Velasco JM, Bines SD, Deziel
DJ, McCarthy WJ, Millikan JD, Prinz RA, Saclarides TJ, eds. Rush
University Medical Center Review of Surgery. 5th ed. Philadelphia,
PA: Saunders/Elsevier; 2011:181-188.
Neurosurgery
Ciric I, Zhao JC, Du H, Findling JW, Molitch ME, Weiss RE,
Refetoff S, Kerr WD, Meyer J. Transsphenoidal surgery for
cushing’s disease: experience with 136 patients. Neurosurgery.
2011 Jul 16. [Epub ahead of print]
Ciric IS. Pituitary carcinoma. World Neurosurg. 2011 Nov 7.
[Epub ahead of print]
Takagi I, Shakur SF, Lukas RV, Eller TW. Spontaneous
radiographic resolution and subsequent redemonstration of
an untreated glioblastoma. J. Neurosurg. 2011 Jul; 115(1):24-9,
2011. Epub 2011 Apr 8.
Karahalios DG, Potts EG, Theodore NT, eds. Image-Guided
Spinal Navigation. (In press)
El-Fiki M, Rosseau G. The 2011 Egyptian Revolution: a neurosurgical perspective, World Neurosurg. 2011 Jul-Aug;76(1-2):28-32.
Ophthalmology
Close, T. Visual field testing. In: Edward DP, Vajaranant TS, eds.
Glaucoma. Oxford UP. (In press)
Ghafouri RH, Lee I, Freitag SK, Pira TN. Bilateral orbital bone
infarction in sickle-cell disease. Ophthal Plast Reconstr Surg.
2011 Mar-Apr;27(2):e26-7.
Delair E, Latkany P, Noble AG, Rabiah P, McLeod R, Brezin A.
Clinical manifestations of ocular toxoplasmosis. Ocul Immunol
Inflamm. 2011 Apr;19(2):91-102.
Rabiah PK. Ophthalmology. In: Daum RS, Canel J, eds.
Specialty Board Review, Pediatrics. 2nd ed. Chicago, IL:
McGraw-Hill; 2011;607-612.
Afshar A, Hariprasad SM, Jampol L, Sheth VS. Use of intravitreal
bevacizumab to treat macular edema in West Nile Virus chorioretinitis. Arch Ophthalmol. 2011. (Accepted)
Sheth VS, Marcet M, Chiranand P, Bhatt H, Lamkin JC, Jager
RD. The Massachusetts Eye and Ear Infirmary Review Manual
for Ophthalmology. 4th ed. Philadelphia, PA: Wolters Kluwer/
Lippincott Williams & Wilkins; 2012.
Otolaryngology
Bhayani MK, Calin GA, Lai SY. Functional relevance of miRNA*
strand in human disease. Mutat Res. 2011 Nov 6. [Epub ahead
of print]
Bhayani MK, Holsinger FC. In-office secondary tracheo-esophageal puncture. In: Cohen JI, Clayman GL, eds. Atlas of Head and
Neck Surgery. Philadelphia, PA: Elsevier/Saunders; 2011:383-88.
Bhayani MK, Holsinger FC. Wide-field total laryngectomy. In:
Cohen JI, Clayman GL, eds. Atlas of Head and Neck Surgery.
Philadelphia, PA: Elsevier/Saunders; 2011:359-72.
Bhayani MK, Weber RS. Head and neck surgery. In: Har-El G.
Otolaryngology Head and Neck Surgery. New York, NY: Thieme
Medical Publishers; 2011. (In press)
Bhayani MK, Weber RS. Hypopharyngeal and cervical
esophageal carcinoma. In: Bailey B. Otolaryngology Head
and Neck Surgery. 5th ed. Baltimore, MD: Lippincott Williams
& Wilkins; 2011. (In press)
Bhayani MK, Yener M, El-Naggar A, Garden A, Hanna EY, Weber
RS, Kupferman ME. Prognosis and risk factors for early-stage
adenoid cystic carcinoma of the major salivary glands. Cancer.
2011 Oct 21. Doi: 10.1002/cncr.26549. [Epub ahead of print]
Murata S, Adachi M, Kioi M, Torigoe S, Ijichi K, Hasegawa Y,
Ogawa T, Bhayani MK, Lai SY, Mitsudo K, Tohnai I. Etodolac
improves 5-FU sensitivity of head and neck cancer cells through
inhibition of thymidylate synthase. Anticancer Res. 2011
Sept;31(9):2893-8.
Cutler J, Truitt T, Atkins J, Winegar B, Lanier B, Schaeffer B,
Raviv J, Henderson D, Duncavage J, Stankiewicz J, Tami T.
First clinic experience: patient selection and outcomes for ostial
dilation for chronic rhinosinusitis. Int Forum Allergy Rhinol. 2011
Nov;1(6):460-5. Doi: 10.1002/alr.20069. Epub 2011 Jun 6.
Plastics
Adler N, Bauer BS. Treatment of congenital melanocytic naevi.
In: Irvine A, Hoeger P, Yan A. Harper’s Textbook of Pediatric
Dermatology. 3rd ed. Oxford: Wiley-Blackwell; 2011. (In press)
Bank J, Bauer BS. Congenital ear deformities. In: Lin SJ, Hijjawi J,
eds. Plastic and Reconstructive Surgery Board Review: Pearls
of Wisdom. 2nd ed. New York, NY: McGraw-Hill Medical;
2011:549-554.
Lentz AK, Plikaitis CM, Bauer BS. Understanding the unfavorable
result after otoplasty: an integrated approach to correction. Plast
Reconstr Surg. 2011 Aug;128(2):536-44.
Plikaitis CM, Bauer BS. Congenital nevi. In: Puri P, ed. Newborn
Surgery. 3rd ed. London, UK; Hodder Arnold; 2011:726-738.
Spear SL, Clemens MW, Howard MA. Considerations of previous
augmentation in subsequent breast reconstruction. In: Spear SL,
Wiley SC, Robb GL, Hammond DC, Nahabedian MY, eds. Surgery
of the Breast: Principles and Art. 3rd ed. Philadelphia, PA: Wolters
Kluwer/Lippincott Williams & Wilkins; 2011:875-83.
Dickie SR, Adamson PA, Warner JP. Alar soft-tissue techniques
in rhinoplasty. In: Shiffman MA, DiGiuseppe A, eds. Advanced
Rhinoplasty: Art, Science, and New Clinical Techniques. Berlin,
Germany; Springer. (In press)
Warner J, Adamson PA. Correction of the crooked tip
in rhinoplasty. Arch Facial Plast Surg. (In press)
continued
2011 Peer-Reviewed Publications and Book Chapters (continued)
Surgical Oncology
Baker MS, Bentrem DJ, Ujiki MB, Stocker S, Talamonti MS.
Adding days spent in readmission to the initial post operative
length of stay limits the perceived benefit of laparoscopic distal
pancreatectomy when compared to open distal pancreatectomy.
Am J Surg. 2011 Mar;201(3):295-9.
Baker MS, Bentrem DJ, Ujiki MB, Stocker S, Talamonti MS.
Adding days spent in readmission to the initial postoperative length
of stay limits the perceived benefit of laparoscopic distal pancreatectomy when compared with open distal pancreatectomy. Am J
Surg. 2011 Mar;201(3):295-9; discussion 299-300.
Baker MS, Mathews, J. Surgical management of chronic pancreatitis. In: Zinner, ed. Maingot’s Abdominal Operations. McGraw
Hill: 2012. (In press)
Moo-Young T, Prinz RA. Adrenal. In: Velasco JM, Bines SD,
Deziel DJ, McCarthy WJ, Millikan KW, Prinz RA, Saclarides TJ,
Moo-Young T, Prinz RA. Parathyroid. In: Velasco JM, Bines
SD, Deziel DJ, McCarthy WJ, Millikan KW, Prinz RA, Saclarides
Moo-Young T, Prinz RA. Thyroid. In: Velasco JM, Bines SD,
Deziel DJ, McCarthy WJ, Millikan KW, Prinz RA, Saclarides TJ,
Moo-Young TA, Moley JF. Carcinoma of the thyroid. In: Johnson
FE, Virgo KS, Audisio RA, Thompson JF, Maehara Y, Margenthaler
JA, Earle CC, Browman GP, eds. Patient Surveillance After Cancer
Treatment. 1st ed. Springer Verlag;2011. (In press)
Moo-Young TA, Prinz RA. Endocrine tumors of the pancreas:
clinical practice, diagnosis and therapy. In: Jarnagin WR, Blumgart
LH. Blumgart’s Surgery of the Liver, Pancreas and Biliary Tract.
5th ed. WB Saunders Co.; 2012. (In press)
Small W, Mulcahy MM, Rademaker A, Bentrem DJ, Benson AB,
Weitner WW, Talamonti MS. Phase II trial of full-dose gemcitabine
and bevacizumab in combination with attenuated three-dimensional conformal radiotherapy in patients with localized pancreatic cancer. Int J Radiat Oncol Biol Phys. 2011 June 1;80(2):476-82.
Chakravarthy AB, Catalano PJ, Martenson JA, Mondschein JK,
Wagner H, Mansour EG, Talamonti MS, Benson AB. Long-term
follow-up of a phase II trial of high-dose radiation with concurrent
5-fluorouracil and cisplatin in patients with anal cancer (ECOG
E4292). Int J Radiat Oncol Biol Phys. 2011 Apr 20. [Epub ahead
of print]
Bilimoria KY, Ko CY, Tomlinson JS, Stewart AK, Talamonti MS,
Hynes DL, Winchester DP, Bentrem DJ. Wait times for cancer
surgery in the United States: trends and predictors of delays. Ann
Surg. 2011 Apr;253(4):779-85.
Vern-Gross TZ, Shivani AT, Chen K, Lee CM, Tward JD,
MacDonald OK, Crane CH, Talamonti MS, Munoz LL, Small W
Jr. Survival outcomes in resected extrahepatic cholangiocarcinoma: effect of adjuvant radiotherapy in a surveillance, epidemiology,
and end-result analysis. Int J Radiat Oncol Biol Phys. 2011 Sep 1;
81(1):189-98. Epub 2010 Oct 23.
Winchester DJ. The positive sentinel node. J Surg Oncol. 2011
Mar 15; 103(4):326-329. Doi: 10.1002/jso.21754.
Winchester DP. The National Accreditation Program for Breast
Centers: Quality improvement through standard setting. Surg
Oncol Clin N Am. 2011 Jul; 20(3):581-6, x.
Ganai S, Winchester DP. Understanding the kinetics of cancer:
implications from prevention to prognostication. Oncology
(Williston Park). 2011 Jan; 25(1):50, 56, 58.
Spiguel L, Yao K, Winchester DJ, Gorchow A, Du H, Sener SF,
Martz B, Turk M, Barrera E, Winchester DP. Sentinel node alone
for node positive breast cancer: a 12-year experience at a single
institution. J Am Coll Surg. 2011 Jul;213(1):122-8;discussion
128-9. Epub 2011 Apr 29.
Williams RT, Yao K, Stewart AK, Winchester DJ, Turk M,
Gorchow A, Jaskowiak N, Winchester DP. Needle versus
excisional biopsy for noninvasive and invasive breast cancer,
report from the National Cancer Data Base, 2003-2008. Ann
Surg Oncol. 2011 Jun 1. [Epub ahead of print]
Yonick DV, Ballo RM, Kahn E, Dahiya M, Yao K, Godellas C,
Shoup M, Aranha GV. Predictors of positive sentinel lymph node
in thin melanoma. Am J Surg. 2011 Mar;201(3):324-7;discussion
327-8.
Urology
Vascular
Albaugh JA, Wayment RO, Kohler TS. Quantification of erectile
dysfunction after prostate cancer treatment. In: McVary KT, ed.
Contemporary Treatment of Erectile Dysfunction: A Clinical Guide.
New York, NY: Humana: 2011:127-150.
Caprini JA. Thrombosis prophylaxis in general surgery. In:
Cameron AM, Cameron JL. Current Surgical Therapy. 10th ed.
Philadelphia, PA: Elsevier Saunders; 2011:883-89.
Jayram G, Decastro GJ, Large MC, Razmaria A, Zagaja GP,
Shalhav AL, Brendler CB. Robotic radical prostatectomy in
patients with high-risk disease: a review of short-term outcomes
from a high volume center. J Endourol. 2011 Mar;25(3):455-7.
Epub 2011 Jan 15.
Schumacher MC, Laven B, Petersson F, Cederholm T, Onelöv E,
Ekman P, Brendler CB. A comparative study of tissue (g)-6 and
(g)-3 polyunsaturated fatty acids (PUFA) in benign and malignant
pathological stage pT2a radical prostatectomy specimens. Urol
Oncol. 2011 Mar 31. [Epub ahead of print]
Szmulewitz RZ, Chung E, Al-Ahmadie H, Daniel S, Kocherginsky
M, Razmaria A, Zagaja GP, Brendler CB, Stadier WM, Conzen
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human prostate cancers. Prostate. 2012 Feb 1; 72(2):157-64. Doi:
10.1002/pros.21416.
Zhang Q, Chen L, Helfand BT, Jang TL, Sharma V, Kozlowski
J, Kuzel TM, Zhu LJ, Yang XJ, Javonovic B, Guo Y, Lonning S,
Harper J, Teicher BA, Brendler CB, Yu N, Catalona WJ, Lee C.
TGF-b regulates DNA methyltransferase expression in prostate
cancer, correlates with aggressive capabilities, and predicts
disease recurrence. PLoS One. 2011;6(9):e25168.
Vartanian V, Park S. Renal Calculi. In: Bope ET, Kellerman RD,
Rakel RE, eds. Conn’s Current Therapy 2011: Expert Consult.
Friedman RJ, Kurth AA, Schnee JM, Clemens A, Noack H,
Eriksson BI, Caprini, JA. Dabigatran etexilate and concomitant
use of nonsteroidal anti-inflammatory drugs or acetylsalicylic acid
in patients undergoing total hip and total knee arthroplasty: no
increased risk of bleeding. J Bone Joint Surg Am. (Accepted)
Merkow RP, Bilimoria KY, McCarter MD, Cohen ME, Raval MV,
Caprini JA, Gordon HS, Co CY, Bentrem DJ. Post-discharge
venous thromboembolism after cancer surgery: extending the
case for extended prophylaxis. Ann Surg. 2011 Jul;254(1):131-7.
Passman MA, McLafferty RB, Lentz MF, Nagre SB, Iafrati MD,
Bohannon WT, Moore CM, Heller JA, Schneider JR, Lohr JM,
Caprini JA. Validation of Venous Clinical Severity Score (VCSS)
with other venous severity assessment tools from the American
Venous Forum, National Venous Screening Program. J Vasc Surg.
2011 Sep 29. [Epub ahead of print]
Gupta N, Yuo TH, Konig G, Dillavou E, Leers SA, Chaer RA, Cho
JS, Makaroun MS. Treatment strategies of arterial steal after arteriovenous access. J Vasc Surg. 2011 Jul;54(1):162-7. Epub 2011
Jan 26.
Hodnett PA, Koktzoglou I, Davarpanah AH, Scanlon TG, Collins
JD, Sheehan JJ, Dunkle ED, Gupta N, Carr JC, Edelman RR.
Evaluation of peripheral arterial disease with nonenhanced
quiescent-interval single-shot MR angiography. Radiology.
2011 Jul:260(1)282-93. Epub 2011 Apr 18.
Koktzoglou I, Gupta N, Edelman RR. Nonenhanced extracranial
carotid MR angiography using arterial spin labeling: improved performance with pseudocontinuous tagging. J Magn Reson Imaging.
2011 Aug;34(2):384-94. Doi: 10.1002/jmri.22628.
Shao M, Gupta N. Arteriovenous hemodialysis access infections.
In: Eskandari MK, Morasch MD, Pearce H, Yao JST, eds. New
Findings in Vascular Surgery. Shelton, CT: People’s Medical Pub
House-USA; 2011:397-408.
Schindler N, Desai T, Babrowski T, Alexander J. Resection
of intracaval leiomyomatosis using abdominal approach and
veno-venous bypass. Ann Vasc Surg: 2011. (In press)
Staff Directory
Cardiac and
Thoracic Surgery
Chief of Cardiac Surgery
Paul Pearson, MD, PhD
(847) 570-2868 Repair and Replacement of Heart
Valves, Thoracoscopic Surgery for
Atrial Fibrillation
General Surgery (continued)
Neurosurgery (continued)
Jose Velasco, MD
(847) 982-1095 Advanced Laparoscopic Surgery,
Thyroid/Parathyroid/Adrenal Surgery, Breast
Surgery
Edward Mkrdichian, MD
847) 570-1440
Brain Surgery, Radiosurgery, Spine
Surgery, Stereotactic Neurosurgery
Neurosurgery
Chief of Thoracic Surgery
John Howington, MD
(847) 570-2868 Minimally Invasive Thoracic Surgery,
Lung and Esophageal Cancer,
Mediastinal Tumors
Department Chair
Julian Bailes, MD
(847) 570-4224
Brain Tumors/Spine Tumors, Brain and
Spine Surgery, Aneurysms, Cervical and
Lumbar Pain Syndromes, Carotid Stenosis,
General Neurosurgery
Subhasis Chatterjee, MD
(847) 570-2868 Valvular Heart Disease, Coronary Artery
Disease, Thoracic Aortic Disease
James Brown, MD
(630) 279-7930 General Neurosurgery
Ki Wan Kim, MD
(847) 570-2868 Lung Cancer, Thoracoscopy,
Pulmonary Resection,
Esophageal Surgery
General Surgery
Division Chief
Woody Denham, MD
(847) 570-1700 General Surgery, Advance
Laparoscopic and Bariatric Surgery
Stephen Haggerty, MD
(847) 570-1700
General Surgery, Advanced
John Linn, MD
(847) 570-1700 Minimally Invasive Surgery,
General Surgery, Advance
Barbara Loris, MD
(847) 570-1700
General Surgery, Breast Surgery
Joseph Muldoon, MD
(847) 570-1700 Colon/Rectal Surgery
Marc Singer, MD
James Spitz, MD
Michael Ujiki, MD
(847) 570-1700 General Surgery, Advanced
Leonard Cerullo, MD
(847) 570-1440 Brain Surgery, General Neurosurgery, Skull
Base Surgery, Trigeminal Neuralgia Surgery
Ivan Ciric, MD
(847) 570-1440
Pituitary Tumors, Brain and Skull Based
Tumors
Geoffrey Dixon, MD
(847) 570-1440 General Neurosurgery, Complex Spine
Surgery
Egon Doppenberg, MD
(847) 570-1440 Minimally Invasive Spine Surgery, Complex
Spine Surgery, Brain and Skull Based
Tumors
Ted Eller, MD
(847) 570-1440 Outpatient Microsurgery of the Spine; Brain
Tumors/Spine, Brain and Spine Surgery;
Aneurysms; Arnold-Chiari Malformation;
Hydrocephalus; General Neurosurgery
Hamad Farhat, MD
(847) 570-1440 Brain/Spine Pathology, Chiari Malformations,
Complex Spine, Endovascular Pathology,
Endovascular Neurosurgery, Hydrocephalus,
Tumors, Vascular Pathology, Minimally
Invasive Spine
Dean Karahalios, MD
(847) 570-1440
Complex Spine Surgery, Minimally Invasive
Spine Surgery, General Neurosurgery
Adebukola Onibokun, MD
(847) 570-1440
Microvascular Decompression Surgery,
Minimally Invasive Spine Surgery, Pituitary
Surgery, Skull Base Surgery, Vascular
Surgery
Gail Rosseau, MD
(847) 570-1440
Cranial Base Surgery, General
Neurosurgery of the Brain, General
Neurosurgery of the Spine
Noam Stadlan, MD
(847) 570-1440
Cervical and Lumbar Total (Artificial) Disc
Replacement, Complex Spine Surgery and
Reconstruction, Minimally Invasive Spine
Surgery, Surgical Treatment of Spine
Disorders
Ophthalmology
Division Chief
Marian Macsai, MD
(847) 657-1860 Ophthalmology, Cornea/Refractive
Surgery, Cataract Surgery
Troy Close, MD
(847) 657-1860 Neuro and Comprehensive Ophthalmology
Joshua Herz, MD
(847) 657-1860 Ophthalmology
Ann Laurenzi-Jones, OD
(847) 657-1860 Contact Lens Fitting for Corneal Disease
and General Contact Lens Fitting Manvi Maker, MD
(847) 657-1860 Medical Retina and Comprehensive
Ophthalmology
Tony Pira, MD
(847) 657-1860 Comprehensive Ophthalmology
Peter Rabiah, MD
(847) 657-1860 Ophthalmology, Pediatric Ophthalmology,
Uveitis, Adult Strabismus
Veeral Sheth, MD
(847) 657-1860 Retina and Comprehensive Ophthalmology
Otolaryngology
Surgical Oncology
Urology (continued)
Division Chief
Mark Gerber, MD
(847) 504-3300 Head and Neck Surgery, Pediatric
Laryngology and Bronchoesophagology
Division Chief
David J. Winchester, MD
(847) 570-1700 Surgical Oncology, Breast Surgery,
Thyroid/Parathyroid/Adrenal Surgery,
General Surgery
Peter Colegrove, MD
(847) 475-8600 General Urology, Incontinence,
Erectile Dysfunction
Mihir Bhayani, MD
(847) 504-3300 Otolaryngology Head and Neck Surgery,
Head and Neck Cancer
Judy Chen, MD
(847) 504-3300 Pediatric Otolaryngology Head and
Neck Surgery
Joseph Raviv, MD
(847) 504-3300 Rhinology, Nasal and Sinus Surgery,
Endoscopic Skull Base Surgery
Ilana Seligman, MD
(847) 504-3300 Pediatric Otolaryngology Head and
Neck Surgery
Michael Shinners, MD
(847) 504-3300
Neurotology, Acoustic Neuroma Surgery,
Cochlear Implants, Stapes Surgery
Plastic Surgery
Division Chief
Bruce Bauer, MD (847) 504-2300 Plastic and Reconstructive Surgery,
Pediatrics
Michael Howard, MD
(847) 504-2300
Plastic and Reconstructive Surgery,
Breast Reconstruction, Wound Care
and Hyperbaric Medicine
Mark Sisco, MD
(847) 504-2300 Aesthetic and Cosmetic Surgery,
Breast Reconstruction, Microsurgery
Jeremy Warner, MD (847) 504-2300 Cosmetic Surgery Face and Body,
Plastic and Reconstructive Surgery
Marshall Baker, MD
(847) 570-1700 Hepto-Pancreatico-Biliary Surgery,
Oncologic Surgery, Pancreatic Cancer,
Liver Cancer, Chronic Pancreatitis
Ermilo Barrera, MD
(847) 570-1700 General Surgery, Oncologic Surgery,
Breast Cancer
Tricia Moo-Young, MD
(847) 570-1700 Thyroid/Parathyroid/Adrenal Surgery,
General Surgery
Richard Prinz, MD
(847) 570-1700 Thyroid/Parathyroid/Adrenal Surgery
Mark Talamonti, MD
(847) 570-1700 Oncologic Surgery, Pancreatic Cancer,
Pancreaticobiliary Disease
David P. Winchester, MD
(847) 570-1700 Breast Cancer, Breast Disease,
Skin Lesions
Katharine Yao, MD
(847) 570-1700 Breast Surgery
Urology
Division Chief
Michael McGuire, MD
(847) 676-2400 General Urology, Pediatric Urology,
Urologic Oncology
Jeffrey Albaugh, PhD, APRN,
CUCNS
(847) 657-5730
Male and Female Sexual Health
Michael Blum, MD
(847) 501-3434 General Urology, Urologic Oncology
(847) 657-5718 Prostate Cancer
Thomas Keeler, MD
(847) 657-5718 General Urology, Pediatric Urology,
Incontinence
Amanda Macejko, MD
(847) 676-2400 General Urology, Minimally Invasive
Surgery, Kidney Stones
Kristian Novakovic, MD
(847) 501-3434 Robotic and Computer-Assisted
Surgery, Urologic Oncology
Sangtae Park, MD
(847) 676-2400 Urologic Oncology, Robotic and
Computer Assisted Surgery
Vascular Surgery
Division Chief
NavYash Gupta, MD
(847) 663-8050 Vascular and Endovascular Surgery;
Minimally Invasive Treatment of Aortic,
Carotid and Peripheral Vascular
Disease; Hemodialysis Access
Joseph Caprini, MD
(847) 663-8050 Venous Thromboembolism and
Coagulation Disorders
Tina Desai, MD
(847) 663-8050 Endovascular Treatment of Vascular
Disease, Minimally Invasive Treatment
of Vascular Disease
Benjamin Lind, MD
(847) 663-8050 Vascular Surgery, Wound Care and
Peripheral Vascular Disease
Omar Morcos, MD
(847) 663-8050 Vascular Surgery, Lower Extremity
Limb Salvage and Hemodialysis
Access
Nancy Schindler, MD
(847) 663-8050 Varicose Veins and Venous Vascular
Problems
Non-Profit
U.S. Postage
Paid
NORTHSHORE
UNIVERSITY
HEALTHSYSTEM
2650 Ridge Avenue
Walgreen 2507
Evanston, IL 60201
(847) 570-2560
northshore.org
Photography: Jon Hillenbrand
NorthShore Evanston Hospital
NorthShore Glenbrook Hospital
Our Commitment to Excellence
NorthShore University HealthSystem is committed to
excellence—bringing the finest physicians, healthcare
professionals and the latest technology together to
provide the very best quality, compassionate care to
the patients and families we are privileged to serve.
To learn more about NorthShore’s clinical, research
and academic excellence, visit northshore.org.
NorthShore Highland Park Hospital
NorthShore Skokie Hospital
Evanston Hospital
2650 Ridge Avenue
Evanston, IL 60201
(847) 570-2000
NorthShore Medical Group
1301 Central Street
Evanston, IL 60201
(847) 570-5235
Glenbrook Hospital
2100 Pfingsten Road
Glenview, IL 60026
(847) 657-5800
NorthShore Foundation
1033 University Place
Suite 450
Evanston, IL 60201
(224) 364-7200
Highland Park Hospital
777 Park Avenue West
Highland Park, IL 60035
(847) 432-8000
Skokie Hospital
9600 Gross Point Road
Skokie, IL 60076
(847) 677-9600
NorthShore
Research Institute
1001 University Place
Evanston, IL 60201
(224) 364-7100

2011 Annual Report - NorthShore University HealthSystem

Transcription

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