final programme
Transcription
final programme
FINAL PROGRAMME Congress Organizers The 81st EAS Congress 1-3, rue du Chantepoulet; P.O. Box 1726 CH-1211 Geneva 1, Switzerland Tel: +41 22 908 0488; Fax: +41 22 906 9140 E-Mail: [email protected] Website: www.kenes.com/eas CONTENTS Welcoming Words III Committees IV Faculty List V EAS Society VI Acknowledgements VII About LyonX Anitschkow Prize in Atherosclerosis Research XI Young Investigator Awards XII General Information XIII Mandatory Conflict of Interest Disclosure XV Instructions for Presenters XVI Overview of Moderated Poster Sessions XVII Poster OverviewXVIII Company Sponsored Educational Symposia XX Opening Ceremony XXIII Social Events XXIV Hall Name Eulogy of Distinguished Scientists XXV Venue Floor Plans XXIX Exhibition Floor Plan and Exhibitors List XXX Sponsor and Exhibitor Profiles XXXI Scientific Programme Sunday, June 2, 2013 1 Monday, June 3, 2013 5 Tuesday, June 4, 2013 15 Wednesday, June 5, 2013 25 Poster Presentations 29 Index 129 II WELCOMING WORDS Dear Colleagues, It is our pleasure to welcome you to the 81st EAS Congress in Lyon, France, from 2 to 5 June 2013. The Congress is hosted by the New French Society for Atherosclerosis. The local Organizing Committee and the EAS Scientific Programme Committee have worked together to prepare a programme that will include the latest developments in the field of atherosclerosis, together with timely reviews presented by outstanding plenary speakers. The EAS meeting remains a unique opportunity to bring together the various actors in the field of atherosclerosis. The EAS 2013 programme is of interest to both junior and established basic scientists, as well as clinical researchers and practitioners. The meeting promotes interactions between these different groups, and provides cutting-edge basic research translatable into disease prevention and treatment. More than 800 posters are on display and organized into interesting and interactive poster sessions. The Congress takes place in the Lyon Convention Center, designed by Renzo Piano, and located downtown on the banks of the Rhone River. Lyon, named a UNESCO Humanities World Heritage Site, is famous not only for world-class landmarks and thousands of years of history but also for its gorgeous food. Ranked among the top European cities for quality of life, Lyon in June provides an excellent opportunity to discover the charm of this unique location. On behalf of the Organizing Committee, we welcome you to Lyon. We are delighted that you joined us for the 81st EAS Congress in 2013 - a stimulating meeting offering enjoyable and rewarding interactions between basic and clinical researchers in the field of atherosclerosis. Philippe Moulin Congress Chair EAS 2013 Petri Kovanen Chairman of the Scientific Programme Committee Alberico L. Catapano EAS President III COMMITTEES CONGRESS CHAIRPERSON Philippe Moulin, France EAS EXECUTIVE COMMITTEE LOCAL ORGANIZING COMMITTEE Alberico L. Catapano, President Olov Wiklund, Vice President M. John Chapman, Past President Petri Kovanen, Secretary & Award Committee Chair Jan Borén, Treasurer Geesje Dallinga-Thie Børge Nordestgaard Arnold von Eckardstein Michal Vrablík Jacques Bonnet, Bordeaux Eric Bruckert, Paris M. John Chapman, Paris Geneviève Derumeaux, Lyon Alain Gadeaux, Bordeaux Michel Krempf, Nantes Michel Lagarde, Lyon Pierre Morange, Marseille Agnes Sassolas, Lyon Bart Staels, Lille SCIENTIFIC PROGRAMME COMMITTEE Petri Kovanen, Finland, Chair Alberico Catapano, Italy Matti Jauhiainen, Finland Jan Kuivenhoven, Holland Jesús Millán Núñez-Cortés, Spain Philippe Moulin, France Børge Nordestgaard, Denmark Marju Orho-Melander, Sweden Gabriele Riccardi, Italy Wolfgang Schneider, Austria Bart Staels, France Lale Tokgozoglu, Turkey IV CONGRESS COMMITTEE Marja-Riitta Taskinen, Finland, Chair Jan Borén, Sweden Alberico L. Catapano, Italy Jesús Millán Núñez-Cortés, Spain Philippe Moulin, France Olov Wiklund, Sweden FACULTY LIST Marcello Arca, Italy Jean-Francois Arnal, France Maurizio Averna, Italy Christie Ballantyne, USA Philip Barter, Australia Christoph Binder, Austria Dirk Blom, South Africa Jacques Bonnet, France Jan Borén, Sweden Adrian J.B. Brady, UK Eric Bruckert, France Sebastiano Calandra, Italy Giuseppina Caligiuri, France François Cambien, France Alberico L. Catapano, Italy M. John Chapman, France Yiannis Chatzizisis, Greece Xavier Collet, France Claudio Cortese, France Jean-Claude Coubard, Canada Filippo Crea, Italy Marina Cuchel, USA Geesje Dallinga-Thie, The Netherlands George Davey-Smith, UK Menno De Winther, The Netherlands John Deanfield, UK Vincent Durlach, France Michel Farnier, France Steven Feinstein, USA Edward Fisher, USA Robert Gerszten, USA François N. Gilly, France Henry Ginsberg, USA Andreas Habenicht, Germany Marten Hofker, The Netherlands G. Kees Hovingh, The Netherlands Frank Hu, USA Patricia Iozzo, Italy Matti Jauhiainen, Finland Dimitris Kardassis, Greece Sander Kersten, The Netherlands George D. Kitas, UK Wolfgang Koenig, Germany Petri Kovanen, Finland Michel Krempf, France Jan Kuivenhoven, The Netherlands Muriel Laffargue, France Laurent Lagrost, France Gilles Lambert, France Eicke Latz, Germany Gary Lewis, Canada Peter Libby, USA Jean-Baptiste Michel, France Jesús Millán Núñez-Cortés, Spain John Millar, USA Gilles Montalescot, France Kathryn Moore, USA Pierre Morange, France Philippe Moulin, France Jan Nilsson, Sweden Steven Nissen, USA Danilo Norata, Italy Børge Nordestgaard, Denmark Vesa M. Olkkonen, Finland Anders G. Olsson, Sweden Marju Orho-Melander, Sweden Chris Packard, UK Klaus Parhofer, Germany Terje Pedersen, Norway Jogchum Plat, The Netherlands Frederick Raal, South Africa Željko Reiner, Croatia Gabriele Riccardi, Italy Angela Rivellese, Italy Robert Ross, Canada Yasushi Saito, Japan Raul D. Santos, Brazil Agnes Sassolas, France Naveed Sattar, UK Wolfgang Schneider, Austria Catherine Shanahan, UK Henrik Sillesen, USA Bart Staels, France Anton Stalenhoef, The Netherlands Evan Stein, USA Erik Stroes, The Netherlands Marja-Riitta Taskinen, Finland Lale Tokgozoglu, Turkey Maciej Tomaszewski, UK Anne Tybjaerg-Hansen, Denmark Luc Van Gaal, Belgium Arie van Tol, The Netherlands Arnold von Eckardstein, Switzerland Michal Vrablík, Czech Republic Olov Wiklund, Sweden Qingbo Xu, UK Laurent Yvan-Charvet, France Rudolf Zechner, Austria Andreas M. Zeiher, Germany APPRECIATION AND THANKS We would like to thank the reviewers of the submitted abstracts and the Young Investigator Award Jury for their valuable help and assistance. V THE EUROPEAN ATHEROSCLEROSIS SOCIETY Advancing and exchanging knowledge of the causes, natural history, treatments and prevenƟon of atheroscleroƟc disease. EAS AcƟviƟes EAS organizes educaƟonal acƟviƟes, including Advanced Courses and an annual Congress. Online educaƟonal content will be available from the Society's E-learning resource, EAS Academy, starƟng summer 2013. The Society is also acƟve in the development and publicaƟon of Guidelines and Consensus PosiƟon Papers on atherosclerosis-related topics. The Society’s journal, Atherosclerosis, brings together from diverse sources papers concerned with research and invesƟgaƟon on atherosclerosis. EAS also supports researchers and clinicians in the eld of atherosclerosis with various grants and awards. EAS Members • • • • • • • have access to online educaƟonal material via the Society's E-learning plaƞorm, EAS Academy receive complimentary online access to the EAS Journal Atherosclerosis benet from reduced registraƟon fee at EAS Congress*, Workshops and Symposia are eligible to apply for EAS Grants and Awards are eligible to apply to aƩend EAS educaƟonal acƟviƟes, including Advanced Courses receive 15% reducƟon on Elsevier books purchased via the EAS Website receive regular scienƟc commentaries and newsleƩers with informaƟon on the Society’s acƟviƟes * Payment of EAS annual membership subscripƟon means you are eligible for member-rate congress registraƟon fee for the following year (i.e. members who have paid membership subscripƟon during 2013 are eligible for member-rate registraƟon fee at EAS 2014 Madrid) For futher details about the ac�vi�es of the Society, or to become a member, visit the EAS website www.eas-society.org or contact us using email address offi[email protected] VI ACKNOWLEDGEMENTS CORPORATE PARTNERS The EAS Executive Committee would like to express its sincere appreciation to the following Corporate Partners for their continued support of the goals and activities of the European Atherosclerosis Society VII ACKNOWLEDGEMENTS The Organising Committee and the EAS Executive Committee would like to express their sincere appreciation to the following organisations for their support in the 81st EAS Annual Congress. PLATINUM SPONSORS GOLD SPONSOR SILVER SPONSOR VIII SPONSORS Exhibitors institutional support IX About Lyon Lyon is France’s second-largest city and capital of the Rhône-Alpes region. Combining an exceptional historical heritage with a natural liking for good food, Lyon is an ideal city for discovering all the charm of the French way of life. A stage for more than 2000 years of history, the city has a remarkable architectural heritage. Expanding towards the east throughout the centuries, while preserving the existing areas, 500 hectares of its city centre became a UNESCO World Heritage Site in 1998. Wandering around Lyon is like embarking on a fascinating journey through time. In each district Lyon displays an astonishing variety of architecture, from the roman theatres and the medieval district, via the elegant peninsula situated between the Rhône and the Saône, to the contemporary and original creations by Renzo Piano, Jean Nouvel and Santiago Calatrava. The city also has a strong academic profile with 120 000 students (12 500 from outside France) in 3 universities, and - with a rich medical history from Rabelais, to Claude Bernard, Alexis Carrel, Marcel and Charles Merieux - was a cradle of pharmaceutical industry. All year round at nightfall the city is lit up thanks to its “Lighting Plan” that shows off some 325 monuments. For night owls, the city is teeming with festive, friendly places, with trendy bars from the Old Lyon to barge-restaurants moored on the banks of the Rhône, not forgetting the wine bars on the peninsula. Lyon has several famous museums, such as the Lumière Institute, on the invention of cinematography, and the Fabric Museum, which traces two thousand years of the history of textile and silk weaving. Located in a wonderful Renaissance building, the Lyon History Museum and the Puppets of the World Museum have formed the Gadagne Museums in Old Lyon since 2009. The Fine Arts Museum is one of the largest museums in France - its collections, spread out over 70 rooms, giving visitors an exceptional journey from Antiquity to Modern Art. Lyon has been the ultimate gastronomic city for centuries, reputed around the world thanks to Chef Paul Bocuse. It now boasts more than 2 000 restaurants, including the famous bouchons (typical local eateries) as well as Michelin star-awarded establishments. From traditional Mères Lyonnaises (19th century cooks for the bourgeoisie) to inspired and innovative young chefs, Lyon is a place for culinary experimentation with new tastes and concepts to be savoured. The city was the first to establish a public bicycle-rental system, and has more than 350 stations with 2500 bicycles available, offering visitors the opportunity to explore by bike the parks beside the river banks and to visit new districts such as the confluences. The EAS Congress venue is situated downtown, within walking distance from several congress hotels and 10-20 minutes from others by public transportation system. Easy to get to, and easy to get about, its various resources and charms at the cross-road of influences from south and north of Europe makes Lyon an ideal venue for the EAS. Your visit to EAS2013 will be both an exciting scientific experience and a memorable taste of French culture. X THE ANITSCHKOW PRIZE THE ANITSCHKOW PRIZE IN ATHEROSCLEROSIS RESEARCH, 2013 Professor Peter Libby Mallinckrodt Professor of Medicine at Harvard Medical School and Chief of the Cardiovascular Division at Brigham and Women’s Hospital, Boston, Massachusetts, USA The EAS is delighted to announce that the recipient of the Society’s prestigious Anitschkow Prize 2013 is Professor Peter Libby, Mallinckrodt Professor of Medicine at Harvard Medical School and Chief of the Cardiovascular Division at Brigham and Women’s Hospital, Boston, Massachusetts. Professor Libby will give the Anitschkow Lecture as part of the Congress Opening Ceremony Sunday June 02, 2013, 18:00. Over the past three decades Prof. Libby has made numerous major discoveries that have changed the way we think about the etiology and potential management of atherosclerotic cardiovascular disease. Prof. Libby’s seminal experimental and translational observations on the pathophysiological pathways leading to plaque formation and destabilization have affected our current knowledge of atherosclerosis with far reaching clinical implications. His work will pave the way for new strategies designed to prevent the onset and progression of atherosclerosis in those who do not yet have manifest cardiovascular disease. Prof. Libby has been a role model, gifted teacher and mentor for a generation of emerging clinical and basic cardiovascular researchers who have been inspired by his ability to translate basic research into clinical setting. This attribute has greatly magnified his contribution to the understanding of atherosclerosis. XI YOUNG INVESTIGATOR AWARDS These annual awards are presented by the EAS for outstanding publications by young scientists in the field of atherosclerosis. Maciej Tomaszewski, UK Department of Cardiovascular Sciences, University of Leicester, Clinical Sciences Wing, Glenfield General Hospital, Leicester, UK. For his publication Inheritance of coronary artery disease in men: an analysis of the role of the Y chromosome, the LANCET, 2012; 379: 915–22. Fadi J Charchar, Lisa D S Bloomer, Timothy A Barnes, Mark J Cowley, Christopher P Nelson, Yanzhong Wang, Matthew Denniff, Radoslaw Debiec, Paraskevi Christofi dou, Scott Nankervis, Anna F Dominiczak, Ahmed Bani-Mustafa, Anthony J Balmforth, Alistair S Hall, Jeanette Erdmann, Francois Cambien, Panos Deloukas, Christian Hengstenberg, Chris Packard, Heribert Schunkert, Willem H Ouwehand, Ian Ford, Alison H Goodall, Mark A Jobling, Nilesh J Samani, Maciej Tomaszewski. Dr Tomaszewski is a specialist in internal medicine. He holds a senior clinical lectureship in cardiovascular medicine in the Department of Clinical Sciences, University of Leicester. He is also a consultant physician in University Hospitals of Leicester NHS Trust. He chairs New Investigators Committee of the International Society of Hypertension. His main research interests focus on genomics and genetics of cardiovascular disease with a particular emphasis on the role of sex chromosomes. Laurent Yvan-Charvet, France Department of Molecular Medicine, Research Center C3M, UMR INSERM U1065/UNS, Nice, France. For his publication Cholesterol efflux and atheroprotection: advancing the concept of reverse cholesterol transport, Cell Stem Cell 2012; Vol 11, Nr.2, p. 195-206. Marit Westerterp, Samuel Gourion-Arsiquaud, Andrew J Murphy, Alan Shih, Serge Cremers, Ross L Levine, Alan R Tall and Laurent Yvan-Charvet. Dr. Laurent Yvan-Charvet obtained his Ph.D. in Endocrinology in 2005 from the University of Paris XI, France. His research work at Columbia University has been mainly focused on how regulation of inflammation and stem cell biology by cholesterol efflux pathways affect cardiovascular diseases. He was the recipient of the Roger Davis Award in 2010 and finalist of the I.H. Page Young Investigator Award in 2011. After a contribution to the development of new therapeutics for cardiovascular diseases at Pfizer, his current research interest as a group leader lies in hematopoietic cell metabolism – a new area of research for cardiovascular diseases. XII GENERAL INFORMATION Venue Cyber Center LYON Congress centre 50 Quai Charles de Gaulle 69463 Lyon cedex 06 Tel. no. 33(0) 4 72 82 26 26 Website: www.ccc-lyon.com A Cyber Centre will be available for participants’ use in the exhibition area during exhibition hours. Dialing Codes & Important Telephone Numbers The International dialing code for France is +33 The Lyon area code is +04 Emergency numbers are as follows: Police - 17; Fire brigade - 18; Medical emergency – 15 or CCC security 04 72 82 27 67 (direct access for medical assistance) Registration / Information / Secretariat Desk The Registration Desk will be situated at the Congress Centre for the duration of the congress and will be open as follows: Opening Hours Sunday, June 2, 11:00 – 20:30 Monday, June 3, 7:30 – 18:30 Tuesday, June 4, 7:30 – 19:00 Wednesday, June 5, 7:30 – 13:00 Badges On registering you will receive your name badge. You are kindly requested to wear your badge during all congress sessions and events. Exhibition Hours Sunday, June 2, 17:30 – End of Welcome Reception Monday, June 3, 10:00 – 17:00 Tuesday, June 4, 10:00 – 17:00 Wednesday, June 5, 10:00 – 12:30 Food & Beverage Abstract Book The congress abstracts will be published in an online Abstract Book available on the website. If you would like to print any of the abstracts while at the congress, please look for the printing stations in the exhibition area. Certificate of Attendance The Certificate of Attendance may be printed from one of the automatic registration areas from Tuesday, June 4, 2013. EBAC CME Accreditation The 81st EAS Congress is accredited by the European Board for Accreditation in Cardiology (EBAC) for18 hours of External CME credits - Up to 3 hours per half-day and up to 6 hours per full day. Each participant should claim only those hours of credit that have actually been spent in the educational activity. EBAC works according to the quality standards of the European Accreditation Council for Continuing Medical Education (EACCME), which is an institution of the European Union of Medical Specialists (UEMS). Participants are kindly requested to scan their badges when they enter and leave the congress area. Banking & Exchange The official currency is the Euro. Foreign currency may be changed at banks during normal banking hours, at hotels, at airports and in exchange offices. All major credit cards are acceptable in most hotels, restaurants and shops. Mail, Messages, Medical Assistance, Lost & Found Please approach the Registration Desk. We wish to thank for providing their products during the Tuesday, June 4 morning coffee break. XIII Language Press Room hours English is the official language of the Congress. All presentations will be made in English. Sunday, June 2, 11:00 – 20:30 Monday, June 3, 7:30 – 18:30 Tuesday, June 4, 7:30 – 19:00 Wednesday, June 5, 7:30 – 13:00 Clothing Clothing is informal for all occasions. Mobile Phones Please note that mobile phones must be switched off during all sessions. Sessions Please make sure to be in session halls on time as all sessions will begin as per schedule. Smoking Policy Smoking is prohibited at all times in the meeting halls, exhibit halls and restrooms. Your compliance is appreciated. Liability and Insurance The Congress Secretariat and Organisers cannot accept liability for personal accidents or loss of or damage to private property of participants and accompanying persons. Participants are advised to take out their own personal travel and health insurance for their trip. A selection of sessions will be webcast and will be available on the Society website after the congress. Paperless Scientific Programme on smartphones and Tablets The paperless application is designed for cross platform access via laptop and mobile devices such as Smartphone, iPad, Android etc. This innovative and intuitive app gives the participant the power to choose and plan and, therefore, maximize his or her time at the congress. Access to the application is via http://eas.ekonnect.co Participants will have full access to the scientific programme and the abstracts. The application has smart search possibilities within the scientific programme by session type and faculty. TRANSPORTATION The public transportation pass, available at the congress center, gives access to any subway, tram, cable car and bus line for the 4 Congress days, Sunday to Wednesday. Safety and Security Congress Organisers Please do not leave bags or suitcases unattended at any time, whether inside or outside session halls. Hotels strongly recommend that you use their safety deposit boxes for your valuables. The 81st EAS Congress Press Room A press lounge with internet access including Wi-Fi is freely available to registered journalists. Journalists must register at the Registration Desk. Upon registration the journalists will receive a press kit including the detailed press briefing schedule. Press releases will be available to the journalists in association to the press briefings in the Press Briefing Room. XIV Webcast 1-3, rue du Chantepoulet; P.O. Box 1726 CH-1211 Geneva 1, Switzerland Tel: +41 22 908 0488 Fax: +41 22 906 9140 E-Mail: [email protected] Mandatory Conflict of Interest Disclosure EAS wishes to promote independence, objectivity, scientific rigor and a fair balance of representation, and has adopted a Conflict of Interest (COI) Disclosure Policy for this purpose. Persons taking part in the Society’s Congress are therefore expected to disclose their financial or in-kind relationships both with health industry that develop, manufacture, distribute or sell health care materials or services, or other organizations that could represent a potential COI. Such relationships exclude personal or family medical care. Full disclosure is expected even when it is not clear whether a relationship or affiliation constitutes a conflicting interest. EAS recognizes that these relationships do not necessarily imply bias or decrease the value of participation. Please note that it is mandatory for all Congress participants to include in their presentation a statement either to disclose any potential or direct conflict of interest, or, alternatively, to state that they have no conflict of interest. » For oral presentations: your conflict of interest disclosure statement should be at the beginning of your presentation (i.e., first or second slide to be the disclosure statement slide) » For poster presentations: your conflict of interest disclosure statement should be included at the bottom of your poster Even if you have no conflict of interest to declare, your presentation must include the statement “I have no potential conflicts of interest to report” Please note that this policy will be strictly enforced – presentation at EAS 2013 Lyon will only be permitted if your slides or poster contain a Conflict of Interest disclosure statement. XV INSTRUCTIONS FOR PRESENTERS Speakers’ Ready Room A Speakers’ Ready Room will be available every day throughout the Congress for speakers. If using a PowerPoint (or any other computer) presentation, please note you need to bring it on a CD, a DVD or on a “disk on key” memory stick (using the USB port in the computer) and load it on one of the congress’ computers in the Speakers’ Ready Room, at least 1 hour before the start of the session. You may supply your own laptop computer as a back-up. If combining video films with PowerPoint, please make sure to check it in the session hall where your lecture is taking place during a coffee or lunch break prior to your session, at least 30 minutes before the start of the session - even after checking it in the Speakers’ Ready Room. Please note that the Congress’ computers in the session halls are being supplied with Windows and Office 2007. Important note For Macintosh users In order to use MAC presentations on a PC compatible computer please note that you need to prepare it according to the instructions below, before bringing it to the Speakers’ Ready Room. » Use a common font, such as Arial, Times New Roman, Verdana, etc. (special fonts might be changed to a default font on a PowerPoint based PC). » Insert pictures as JPG files (and not TIF, PNG or PICT - these images will not be visible on a PowerPoint based PC). » Use a common movie format, such as AVI, MPG and WMV (MOV files from QuickTime will not be visible on a PowerPoint based PC). You may use your own Macintosh laptop computer as a back-up. In such a case, please confirm that it has a VGA socket for external signal and come to check it first in the Speakers’ Ready Room as soon as you arrive and later on in the session hall where your lecture is taking place during the coffee or lunch break prior to your session, at least 30 minutes before the start of the session. Please note that VHS Video projection, 35 mm’ slide projection and Overhead projection (projection of transparencies) will not be available. INSTRUCTIONS FOR POSTER PRESENTERS Posters will be on display for the entire congress. Please check the Scientific Programme to see the exact poster board number, date, and time of the poster discussion groups. Posters may be mounted from Sunday, June 2 from 15:30. Presenters are requested to stand next to their posters during the lunchtimes on » Monday June 3 from 12:40 - 14:45 and » Tuesday, June 4 from 12:40 - 14:45. The organisers are not responsible for any posters that have not been removed by the end of sessions on Wednesday, June 5. MODERATED POSTER PRESENTATIONS EAS is proud to have moderated poster sessions that will be located in the Exhibition area, providing the unique opportunity for convivial scientific discussions and exchange. For further details please refer to the Overview of Moderated Poster Sessions on the following page. XVI OVERVIEW OF MODERATED POSTER SESSIONS Session Topic Moderator Poster Number Moderated Session A: Monday, June 3, 13:40 – 14:40 1 Endothelium and atherothrombosis Yiannis Chatzizisis, Greece T1: M1-M8 2 Regulation of cellular lipid metabolism in atherogenesis Bart Staels, France T2: M59-M66 3 Role of lipases in lipid and lipoprotein metabolism Geesje Dallinga-Thie, Netherlands T2: M67-M74 4 Evaluation and treatment of cardiovascular risk factors in the young and the elderly George Davey-Smith, UK T3: M117-M125 5 Inflammation and HDL Dimitris Kardassis, Greece T2: M75-M81 6 Thrombosis and hemostasis: relation to atherothrombosis and lipoproteins Pierre Morange, France T1: M9-M14 7 Fatty acids influence atherosclerosis and its risk factors: the double bonds decide Michel Lagarde, France T3: M126-M130 8 Insulin-resistant states: modulators of lipid metabolism and cardiovascular disease Klaus Parhofer, Germany T3: M131-M139 Moderated Session B: Tuesday, June 4, 12:40 – 13:40 9 Cell dysfunctions in atherogenesis Catherine Shanahan, UK T1: M15-M22 10 Angiogenesis Jan Nilsson, Sweden T1: M23-M30 11 Lifestyle Angela Rivellese, Italy T3: M140-M148 12 CV risk factors 1 Jacques Bonnet, France T3: M149-M157 13 Atherosclerosis-regulating factors in mouse and man 2 Christoph Binder, Austria T1: M31-M38 14 Multiple roles of HDL and its transporters in atherosclerosis and related diseases Arie van Tol, Netherlands T2: M82-M89 15 Novel insights into the role of micronutrients in cardiovascular risk and disease Eric Bruckert, France T3: M158-M164 16 Treatment of dyslipidemia: from guidelines to goals and mechanisms Anders G. Olsson, Sweden T2: M90-M99 17 Imaging of the arterial wall as a diagnostic and prognostic indicator of atherosclerotic disease Lale Tokgozoglu, Turkey T3: M165-M171 Moderated Session C: Tuesday, June 4, 13:40 – 14:40 18 Immunity and atherosclerosis Menno De Winther, Netherlands T1: M39-M44 19 Metabolic regulation of apoliprotein A-I-containing lipoproteins Laurent Lagrost, France T2: M100-M106 20 Cardiovascular disease and its prevention in patients with chronic inflammatory and chronic renal disease Naveed Sattar, UK T3: M172-M181 21 Primary dyslipidemia Sebastiano Calandra, Italy T2: M107-M116 22 Inflammation and infection in experimental and clinical atherosclerosis Giuseppina Caligiuri, Italy T1: M45-M53 23 Regulation of ischemia reperfusion injury Jean-Francois Arnal, France T1: M54-M58 24 Exercise and cardiovascular health: both quantity and quality count Matti Jauhiainen, Finland T3: M182-M187 CV risk fators 2 Anne Tybjaerg-Hansen, Denmark T3: M188-M195 25 ACKNOWLEDGEMENT OF POSTER MODERATORS EAS is indebted to the distinguished scientists and clinicians who have kindly accepted the role of moderator during the Moderated Poster Sessions at the Congress. XVII POSTER OVERVIEW Posters will be on display from Monday June 3 – Wednesday June 5. Poster presenters are requested to stand by their posters during lunch breaks Track 1: VASCULAR BIOLOGY OF THE ARTERIAL WALL Topic Track 2: LIPID AND LIPOPROTEIN METABOLISM: FROM ALTERATIONS TO TREATMENTS Poster Board Numbers 1-134 Endothelial cells and function 1-20 Endothelial dysfunction clinical assessment 21-29 Smooth muscle cells 30-44 Extracellular matrix and calcification 45-67 Gene expression 68-74 Infection and atherosclerosis 75-82 Inflammation 83-103 Innate immunity 104-120 Adaptive immunity 121-128 Hormones and atherosclerosis 129-134 Topic Sub-topic apoB-Containing lipoproteins Modified lipoproteins 135-137 apoB-Containing lipoproteins Lp(a) 138-140 HDL CETP 141-145 HDL Cholesterol efflux 146-152 HDL Function and metabolism 153-164 HDL apoA1 functions 165-168 Intracellular metabolism 169-177 Lipases and lipoprotein metabolism 178-183 Lp-PLA2 184-195 Biomarkers Lipid metabolism 196-199 Dyslipidaemia: epidemiology, biomarkers HDL 200-205 Dyslipidaemia: epidemiology, biomarkers 206-227 Familial hypercholesterolaemia 229-246 Primary dyslipidaemia 247-255 Secondary dyslipidaemia XVIII Poster Board Numbers 135-330 256-262 Genetics HDL metabolism 263-266 Genetics Lipid metabolism 267-282 Lipid-lowering therapy Ezetimibe 283-290 Lipid-lowering therapy Miscellaneous 291-296 Lipid-lowering therapy Nicotinic acid 297-299 Lipid-lowering therapy PCSK9 300-304 Lipid-lowering therapy Statins 305-330 Track 3: RISK FACTORS, EPIDEMIOLOGY, PREVENTION, AND TREATMENT OF CARDIOVASCULAR DISEASES Topic Sub-topic Poster Board Numbers 331-684 Topic Sub-topic Poster Board Numbers 331-684 Lifestyle and CV risk Miscellaneous 578-580 Lifestyle and CV risk Tobacco 581-584 Lifestyle and CV risk Therapeutic education 585-588 Cardiovascular epidemiology 331-351 Woman and cardiovascular risk 352-356 Biomarkers 357-370 Functional assessment of arterial wall 371-383 Lifestyle and CV risk Psychosocial factors 589-591 Nutrition and CV risk Alcohol 592-593 Nutrition and CV risk Antioxidants 594-597 Nutrition and CV risk Carbohydrates/ fibres 598-600 Imaging IMTc 384-387 Imaging Calcifications assessment 388-396 Imaging Miscellaneous 397-402 Imaging Vulnerability 403-408 Nutrition and CV risk Fatty acids 601-605 Genetics 409-426 Nutrition and CV risk Miscellaneous 606-619 Obesity and fat distribution 427-445 Omega-3 fatty acids Metabolic syndrome 446-467 Phytosterols NASH and related disorders 468-480 Treatment Miscellaneous 635-647 Treatment Blood pressure treatment 648-653 Sub inflammatory states 481-494 620-631 632-634 Diabetes macroangiopathy Dyslipidaemia 495-499 Diabetes macroangiopathy Treatment 500-507 Intravascular procedures 654-660 508-523 Miscellaneous 665-700 Nephropathy 524-536 Phytosterols 634-636 Thrombosis 537-551 Aneurysms Diabetes macroangiopathy Miscellaneous Arteriopathy Lifestyle and CV risk Exercise Treatment Miscellaneous 637-649 552-554 Treatment Blood pressure treatment 650-655 555-561 Intravascular procedures 656-622 562-577 Miscellaneous 633-684 Please note that posters of Abstract Presenters that were not registered to the Congress by the deadline, were not allocated poster boards. Such Abstract Presenters are requested to approach the Poster Helpdesk to receive an available poster board onsite. XIX EDUCATIONAL SYMPOSIA AND SPECIAL SESSIONS SUNDAY, JUNE 2, 2013 13:30-15:00 - EBAC ACCREDITED EDUCATIONAL PROGRAMME - Claude Bernard Hall Supported by an unrestricted educational grant from AstraZeneca ADVANCES IN THE UNDERSTANDING OF CARDIOVASCULAR DISEASE AND DYSLIPIDAEMIA IN DIABETES Programme created in collaboration with Sahlgrenska Academy, University of Gothenburg See page 1 of the Scientific Programme 14:15-15:00 - Special Lecture - Marcel Mérieux Hall HYPERCHOLESTEROLEMIA – WHAT CAN WE DO FOR HIGH-RISK PATIENTS? Sponsored by Amgen See page 2 of the Scientific Programme 15:15-16:00 - Special Lecture - Michel Macheboeuf Hall CETP INHIBITION: WHAT’S NEW? Sponsored by Merck See page 2 of the Scientific Programme 16:20-17:50 - Educational Symposium - Michel Macheboeuf Hall NEW STRATEGIES FOR THE MANAGEMENT OF PATIENTS WITH HoFH Sponsored by Aegerion See page 3 of the Scientific Programme XX MONDAY, JUNE 3, 2013 13.00–14.30 - Educational Programme - Claude Bernard Hall CLINICAL ADVANCES IN DIFFICULT-TO-TREAT PATIENTS WITH HYPERCHOLESTEROLEMIA Sponsored by Sanofi/Regeneron & Genzyme See page 9 of the Scientific Programme 17.00–18.30 - Educational Symposium – Anitschkow Hall ON THE FOREFRONT OF CHOLESTEROL MANAGEMENT: CLINICAL CONSIDERATIONS AND PRACTICAL APPROACHES BEYOND STATINS Sponsored by MSD See page 11 of the Scientific Programme 17.00–17.45 - KOWA Special Lecture - Claude Bernard Hall NORMALISING DYSLIPIDEMIA AND REVERSING ATHEROSCLEROSIS IN CARDIO-METABOLIC DISEASE Sponsored by KOWA See page 13 of the Scientific Programme 17.00–17.45 - Special Lecture - Michel Macheboeuf Hall THE ROLE OF PLANT STANOLS/STEROLS IN THE MANAGEMENT OF DYSLIPIDAEMIAS Sponsored by BASF, Danone, Raisio, Unilever See page 14 of the Scientific Programme XXI TUESDAY, JUNE 4, 2013 13:00–14:30 - Educational Symposium – Anitschkow Hall CONTEXT AND FUTURE CHALLENGES IN THE EFFECTIVE MANAGEMENT OF DYSLIPIDAEMIA Sponsored by Roche See page 19 of the Scientific Programme 15:40–16:40 - Meet the Expert - Michel Macheboeuf Hall CLINICAL EXPERIENCE OF LOMITAPIDE THERAPY IN PATIENTS WITH HoFH DURING CLINICAL TRIALS Sponsored by Aegerion See page 23 of the Scientific Programme 17:00–19:00 - Reviewer & Author Workshop - Meeting room “Rene Leriche” Sponsored by Elsevier See page 23 of the Scientific Programme XXII Opening Ceremony SUNDAY JUNE 2, 2013, 18:00 N.N. Anitschkow Hall WELCOME FROM THE EAS PRESIDENT Alberico L. Catapano, Italy WELCOME FROM THE PRESIDENT OF THE CLAUDE BERNARD LYON UNIVERSITY François Noel Gilly, France WELCOME FROM THE NFSA PRESIDENT Michel Krempf, France IAS AND EAS WORKING TOGETHER Philip Barter, IAS President, Australia WELCOME FROM THE CONGRESS CHAIRPERSON Philippe Moulin, France Choir Resonance IUFM de Lyon, Conductor: Jean Duvillard Magnificat (John Rutter) INTRODUCTION OF THE ANITSCHKOW PRIZE WINNER Alberico L. Catapano, Italy THE ANITSCHKOW LECTURE Peter Libby, USA Choir Resonance IUFM de Lyon, Conductor: Jean Duvillard Les Djinns (Victor Hugo – Gabriel Fauré) Followed by a Wine and Cheese Welcome Reception Choir Resonance IUFM de Lyon, Conductor: Dany Landry Carmina Burana (Carl Orff) XXIII SOCIAL EVENTS PROGRAMME SUNDAY, JUNE 2 2013 OPENING CEREMONY FOLLOWED BY A WINE AND CHEESE WELCOME RECEPTION Guests will enjoy glorious choir music in the opening ceremony followed by a Wine and Cheese Welcome Reception in the exhibition area at the congress centre. For non-registered participants €15 MONDAY, JUNE 3 2013 FACULTY DINNER (for invitees only) This event is exclusive to Invited Speakers Time: 20:00 Pick-up from Hilton Hotel: 19:30 TUESDAY, JUNE 4 2013 EAS INTERNATIONAL EVENING (ticket required) A ‘not to be missed’ networking evening will be held in at Lyon’s imposing City Hall. This magnificent building, with its tall clock tower and blue-domed pavilions, is an excellent example of the French tradition of dignified government buildings. The event is catered by JP Pignol who was named “meilleur ouvrier de France” (MOF Best Chef of France in 1979) Tickets can be purchased at the Registration Desk (Limited Availability) Time: 20:00 Ticket Price: €35 and €25 for students. XXIV HALL NAME EULOGY OF DISTINGUISHED SCIENTISTS Nikolai N. Anitschkow (1885-1964) Professor of the Department of Pathological Physiology of the Military Medical Academy St. Petersburg, Russia In 1913, experimental pathologist Dr. Nikolai N. Anitschkow showed that simply feeding to rabbits purified cholesterol dissolved in sunflower oil induced vascular lesions closely resembling those of human atherosclerosis, both grossly and microscopically. Controls fed with only the sunflower oil showed no lesions. It is fair to say that this paper marked the beginning of the modern era of atherosclerosis research. Dr. Anitschkow was not only a keen-eyed structural pathologist and a careful experimentalist; he thought in terms of function and time-related pathogenesis. However, the landmark studies by Dr. Anitschkow were largely rejected at the time. An important reason for this was that the findings were inconsistent with the prevailing view of atherosclerosis. It was generally accepted to be an inevitable accompaniment of aging (the “senescence hypothesis”). If the full significance of his findings had been appreciated at the time, we might have saved more than 30 years in the long struggle to settle the cholesterol controversy. In honor of Dr. Nikolai N. Anitschkow, the “Anitschkow Prize in Atherosclerosis Research” awarded annually by the EAS recognizes outstanding research in the field of atherosclerosis and linked metabolic disturbances. XXV Claude Bernard (1813-1878) Physiologist. Born: 1813, Saint-Julien near Lyon. Died: 1878, Paris By the age of 21, Bernard had already written several plays and set off to Paris, France, to show them around. He entered the Faculty of Medicine, obtaining a medical degree in 1843. He became an assistant to François Magendie, one of France’s most prominent--and controversial--physiologists. In 1855, when Magendie died, Bernard took his place as Professor of Experimental Medicine at the College de France. Bernard, who tended to be more disciplined and organized than Magendie had been, began attracting more and more scientific attention to the comparatively new discipline. Bernard found that the stomach was not the sole digestive organ: while the stomach began the digestive process, much more digestion took place throughout the small intestine. He also demonstrated the importance of the pancreas, whose secretions were clearly necessary to break down fat molecules, and later went on to identify the various nerves that control gastric secretion. In 1857, Bernard isolated glycogen in the liver of animals and evidenced that it served as the body’s reserve supply of carbohydrates. In 1851, he discovered that certain specific nerves governed the dilation and constriction of blood vessels. He theorized that, by doing so, the body was better able to control its distribution of heat. While studying the vasomotor system, Bernard also discovered that the blood’s red corpuscles carry oxygen from the lungs to body tissues. He therefore concluded that the body must be under the control of one strong and central regulating force. Bernard’s theory, although widely accepted today, appeared quite radical in his own time, when most scientists believed that the body’s various organs acted quite independently of each other. In 1865, Bernard published the highly influential textbook, An Introduction to the Study of Experimental Medicine, which won him election to the prestigious French Academy in 1869. He even served in the French senate under Napoleon III (1808-1873) and, when he died in 1878, Bernard became the first scientist to be given a national funeral. XXVI Marcel Mérieux (1870-1937) Biochemist. Born: 1870 Terrenoire near Lyon. Died: 1937. In 1894 Marcel Mérieux became the personal assistant of Émile Roux at the Pasteur Institute of Paris. As a student of Louis Pasteur he worked on the bacillus Yersinia pestis and on asepsis. He founded a private laboratory in order to produce an anti-streptococcic serum used against puerperal fever in Lyon. This laboratory would become Institut Mérieux, today part of Sanofi Pasteur. He set up a private research lab. In 1937, his son, Dr. Charles Mérieux, took up the reins of his father’s laboratory. In the 1940’s, Charles Mérieux introduced a technique developed by the Dutch Professor Frenkel - in vitro culture – which revolutionized the manufacture of vaccines and led to the production of reagents for in vitro diagnostic testing. In 1963, his grandson Alain Mérieux, established the diagnostics company, bioMérieux. Today it is part of the Institut Mérieux, whose companies work in the area of diagnostics, immunotherapy, food safety and nutrition. Michel Macheboeuf (1900-1953) Head of laboratory at Pasteur Institute, Paris (1929). Professor of Biochemistry at Lille University, then Bordeaux University (1936-1942). Head of department of biochemistry at Pasteur Institute, Paris (1942-1954). Born: 1900, Châtel-Guyon (Puy-de-Dome). Died: 1953, Paris. In 1929, Michel Macheboeuf, working at the Pasteur Institute in Paris, reported the isolation from horse serum of a stable, watersoluble lipoprotein that could be precipitated from a neutral 50% saturated ammonium sulfate extract of serum by lowering the pH to 3.8. This lipoprotein contained 59% protein and 41% lipid, which consisted of 18% cholesterol and 23% phospholipid and could be redissolved in water to form a clear solution. Later on it was shown that this lipoprotein was an α-globulin and had the same composition as the α-lipoprotein that we now recognize as HDL. Adapted from: Olsson R, J. Nutr. February 1, 1998 vol. 128 no. 2 439S-443S Macheboeuf M., Recherches sur les phosphoaminolipides et les steroids du serum et du plasma sanguins. II Etude physiochimique de la fraction proteidique la plus riche en phospholipids et in sterides. Bull. Soc. Chim. Biol.,1929; 11:485–503 XXVII René Leriche (1879-1955) Surgeon. Born: 1879, Roanne, Loire. Died: 1955, Cassis, near Marseille. Leriche began his career in Lyon. In 1924 he was appointed Professor of Surgery at the University of Strasbourg. In 1927 he was made an honorary Fellow of the Royal College of Surgeons of England. He was the first surgeon to be made Professeur au Collège de France. Leriche was a technically gifted surgeon and had flair for teaching. He emphasized the importance of regarding the patient as a whole - the holistic approach. He was a flamboyant character who enjoyed French cuisine and fine wine. He had a fine collection of art - one of his patients was Matisse. He was also an excellent public speaker who never needed notes. Leriche gave his name to two syndromes: Leriche’s syndrome - Impotence and buttock claudication and absent pulses in the groin and legs due to saddle embolus or atherosclerosis at the aortic bifurcation. Sudek-Leriche syndrome - Aseptic necrosis of bone following injury (also known as Sudek atrophy) He devised a surgical procedure, the sympathectomy, to increase blood flow within arteries. Leriche was awarded the Lister Medal in 1939 for his contributions to surgical science. Adapted from: Wikipedia XXVIII VENUE FLOOR PLANS XXIX EXHIBITION FLOOR PLAN @ 16 17 06 14 05 12 13 07 09 08 11 10 TO POSTER AREA 04 02A 03 01 ENTRANCE ENTRANCE EXHIBITION LIST Company Aegerion XXX Booth # 5 Amgen 14 B. Braun Avitum AG 2A Denka Seiken 8 DIADEXUS Inc 12 European Atherosclerosis Society 7 Fresenius Medical Care 9 Itamar Medical Ltd 17 Merck 3 Mercodia 16 NSFA 11 Randox Cardiology 1 Sanofi/Regeneron/Genzyme 4 Synageva Biopharma 10 Wisepress Medical Bookshop 6 SPONSOR AND EXHIBITOR PROFILES Aegerion Pharmaceuticals, Inc. 101 Main Street - Suite 1850 Cambridge, MA 02142 USA www.aegerion.com Aegerion Pharmaceuticals is a biopharmaceutical company dedicated to the development and commercialization of novel life-altering therapies for patients with debilitating, often fatal, rare diseases. Founded in 2005, our emerging global organization is based in Cambridge, Massachusetts with an established presence in Europe, and is growing internationally. In 2013, we successfully launched in the US our first product, Juxtapid™ (lomitapide) as an adjunct to a low fat diet and other lipid lowering treatments, including apheresis, for patients with homozygous familial hypercholesterolemia (HoFH). Lomitapide is currently in review by the European Medicines Agency (EMA). The company’s mission statement is: To develop therapeutic compounds on behalf of people with serious diseases using the highest ethical standards with demonstrated patient benefits. Aegerion is motivated by its commitment to patients first. We are also attentive to our core values of integrity, innovation, responsibility to healthcare providers, development of employees and always – scientific excellence. Amgen (Europe) GmbH Dammstrasse 23 6301 Zug Switzerland www.amgen.com Amgen discovers, develops, manufactures and delivers innovative human therapeutics. A biotechnology pioneer since 1980, Amgen was one of the first companies to realise the new science’s promise by bringing safe, effective medicines from lab to manufacturing plant to patient. Amgen therapeutics have changed the practice of medicine, helping millions of people around the world in the fight against cancer, kidney disease, rheumatoid arthritis, bone disease and other serious illnesses. With a deep and broad pipeline of potential new medicines, Amgen remains committed to advancing science to dramatically improve people’s lives. To learn more about our pioneering science and vital medicines, visit www.amgen.com. Follow us on twitter at www.twitter.com/amgen. AstraZeneca SE-431 83 Mölndal Sweden www.astrazeneca.com AstraZeneca is a global, innovation-driven biopharmaceutical business that focuses on the discovery, development and commercialisation of prescription medicines, primarily for the treatment of cardiovascular, metabolic, respiratory, inflammation, autoimmune, oncology, infection and neuroscience diseases. AstraZeneca operates in over 100 countries and its innovative medicines are used by millions of patients worldwide. XXXI BASF BASF’s Nutrition & Health division develops, produces and markets a comprehensive range of products and services for the human and animal nutrition, pharmaceutical as well as flavor and fragrance industries. The division strives to contribute to a better life through improving the nutrition, health and wellbeing of people across the world. Important human nutrition products are vitamins and carotenoids, plant sterols, emulsifiers and omega-3 fatty acids. Its feed additives such as vitamins, carotenoids, enzymes and organic acids make Nutrition & Health a worldwide leader for the animal nutrition market. The division provides the pharmaceutical industry with active ingredients such as caffeine and ibuprofen, as well as excipients and custom synthesis services. Furthermore, it produces aroma ingredients such as citral, geraniol and L-menthol for the flavor and fragrance industry. B. Braun Avitum AG Schwarzenberger Weg 73-79 34212 Melsungen Germany www.bbraun.com B. Braun is one of the world´s leading healthcare suppliers. Our four divisions orient their products and services toward different medical fields: hospital, surgery, private practice (medical care and doctors´ offices) and extracorporeal blood treatment. The B. Braun Avitum Division concentrates on therapy systems for hemodialysis, acute dialysis and apheresis and is one of the largest systems providers in the field of extracorporeal blood treatment worldwide. The competency held herein extends from high-grade equipment and disposables to an international network of dialysis centers. As a full-range systems provider B. Braun Avitum works as an interface, linking theory to practice. DANONE 17 Boulevard Haussmann 75009 Paris cedex France www.danone.com DANONE is one of the largest healthy food companies worldwide with 4 expertise areas in dairy products, bottled waters, baby and medical nutrition. Its mission is to bring health through food to as many people as possible at all the ages of the life, in more than 120 countries. DANONE and its 100,000 employees are entirely focused on this mission and R&D budget is dedicated to projects associated with nutrition and health. Its major research centres, Palaiseau (France) and Wageningen (Netherlands) have established more than 200 external scientific partnerships, to develop products with relevant, scientifically proven health benefits. XXXII DENKA SEIKEN CO.,LTD. Nihonbashi Mitsui Tower 2-1-1, Nihonbashi-Muromachi Chuo-ku, Tokyo 103-8338 Japan www.denka-seiken.co.jp Denka Seiken manufactures clinical chemistry and latex-enhanced serum protein reagents for automated chemistry analyzers such as CRP, Lp(a), Myoglobin, HDL-C, LDL-C, etc. Denka Seiken currently features a reagent that can quantitatively determines small, dense low-density lipoproteins (small, dense LDL). The s LDL-EX “SEIKEN” is a homogeneous assay consisting of two ready-to-use liquid reagents to be used on automated chemistry analyzers. The test is fully automated and has within-run precisions of 1 – 2 %. Test result is available in 10 minutes. The assay methodology correlates well with the traditional ultracentrifugation method. diaDexus, Inc. 349 Oyster Point Blvd South San Francisco, CA 94080 USA www.diadexus.com diaDexus, Inc., is a biotechnology company focused on the development and commercialization of novel in vitro diagnostic tests for cardiovascular disease. The PLAC Test for Lp-PLA2 (lipoprotein-associated phospholipase A2) is a blood test that measures the enzyme activity of Lp-PLA2. Lp-PLA2 is a vascular-specific inflammatory enzyme implicated in the formation of rupture-prone plaque. Plaque rupture and thrombosis cause the majority of cardiac events. The PLAC Test helps to identify the patients with hidden CVD risk independent from traditional risk factors. Visit www.plactest.com for more information. European Atherosclerosis Society Kronhusgatan 11 Gothenburg 411 05 Sweden www.eas-society.org The Society’s goal is to provide a framework for concerted scientific and clinical discussion of new developments in basic research, diagnosis and therapy of atherosclerosis. EAS is active in the publication of Guidelines and Consensus Position Papers, and its official Journal is Atherosclerosis. The Society organizes an annual Congress for approximately 2000 delegates, and runs a programme of Advanced Courses for both basic scientists and clinicians. Our website, www.eas-society.org, contains information on activities involving the Society and its members, and online educational material, including webcasts recorded both at Congress and Advanced Courses, Featured Commentaries, and a newsfeed direct from theheart.org. XXXIII Fresenius Medical Care Deutschland GmbH Else-Kröner-Str. 1 Bad Homburg v.d.H., 61352 Germany www.fmc-ag.com Fresenius Medical Care is the world’s largest integrated provider of products and services for individuals undergoing dialysis because of chronic kidney failure, a condition that affects more than 2 million individuals worldwide. In patients suffering from severe liver failure (like acute or “acute-on-chronic”), elimination of toxins by dialysis is not enough because here albumin-bound toxins have to be removed too. With Prometheus®, Fresenius Medical Care offers a therapy system that combines a procedure where a fraction of plasma is separated from blood to remove albumin bound toxins by adsorption with hemodialysis to clear the blood from water soluble substances. Itamar Medical Ltd 9 Halamish St. PO Box 3579 Caesarea 38900 Israel www.itamar-medical.com Itamar Medical a publicly-traded medical technology company developing state-of-the-art biomedical products based on a proprietary signal for noninvasive, early detection of heart disease & obstructive sleep apnea. Technology & Product: The patented Peripheral Arterial Tone (PAT®) signal -- the noninvasive “window” to both the cardiovascular and autonomic nervous systems. EndoPAT™: The only noninvasive, FDA-cleared device diagnosing endothelial dysfunction – the early indicator of arterial health. This 15-minute, office-based diagnostic is used by Mayo Clinic, Framingham Heart Study & others. WatchPAT™: Convenient, portable sleep apnea testing device installed by the patient in their own home. Genzyme, a Sanofi Company Genzyme Corporate Offices 500 Kendall Street Cambridge, MA 02142 USA www.genzyme.com Genzyme has pioneered the development and delivery of transformative therapies for patients affected by rare and debilitating diseases for over 30 years. With a focus on rare diseases and multiple sclerosis, we are dedicated to making a positive impact on the lives of the patients and families we serve. Genzyme’s portfolio of transformative therapies, which are marketed in countries around the world, represent groundbreaking and life-saving advances in medicine. In partnership with Isis Pharmaceuticals, we are committed to the development of potential innovative treatments for severe Familial Hypercholesterolemia (severe FH). XXXIV Kowa 105 Wharfedale Road Winnersh Triangle Wokingham, RG41 5RB UK www.kowa.co.jp/eng Kowa Company, Ltd. (KCL) is a privately held multinational company headquartered in Nagoya, Japan. Established in 1894, KCL is actively engaged in manufacturing activities in the fields of pharmaceutical, life science, information technology, textiles, machinery and various consumer products. KCL’s pharmaceutical division is focused on cardiovascular therapeutics, with sales of the company’s flagship product, LIVALO (pitavastatin) making sales of 51 billion JPY during 2012 in Japan. KCL has research and commercial affiliates in the US (Kowa Research Institute and Kowa Pharmaceuticals America) and Europe (Kowa Research Europe and Kowa Pharmaceutical Europe). Mercodia AB Street: Sylveniusgatan 8A Uppsala 754 50 Sweden www.mercodia.com Mercodia AB is a Swedish biotech company focusing on the development of immunoassays for research within the field of metabolic disorders. Our assays are applicable to both animal and human models and are used for research ranging from basic scientific studies to large pre-clinical and clinical phase trials. The company was founded in 1991 and is today a world-leading supplier of products to all major international markets. More than ninety percent of our production is exported from our facilities in Uppsala to approximately 100 different countries around the world. MSD One Merck Drive Whitehouse Station, NJ 08889 USA www.merck.com Today’s Merck is a global healthcare leader working to help the world be well. Merck is known as MSD outside the United States and Canada. Through our prescription medicines, vaccines, biologic therapies, and consumer care and animal health products, we work with customers and operate in more than 140 countries to deliver innovative health solutions. We also demonstrate our commitment to increasing access to healthcare through far-reaching policies, programs and partnerships that donate and deliver our products to the people who need them. For more information, visit www.merck.com Raisio Group Raisio Group is an international expert in plant-based nutrition with strong international and local food brands. Benecol® is the expert brand in cholesterol reduction and a pioneer in the cholesterol lowering functional food category. Raisio Group produces the unique cholesterol-lowering ingredient, Plant stanol ester, and licenses the Benecol brand worldwide. Benecol products are manufactured and sold by local food companies in 30 countries on five continents. Over 70 clinical studies support the use of Benecol as an effective, easy and safe dietary tool to lower LDL-cholesterol. The cholesterol-lowering effect of Benecol is additive to those of a healthy diet and statin medication. XXXV NSFA 13 Avenue des Arts 94100 Saint maur France http://www.nsfa.asso.fr French Atherosclerosis Society (NSFA) is composed of more than 200 members and is involved in the promotion of fundamental and clinical researches in the domain of atherosclerosis and thromboembolic complications. NSFA supports institutional research laboratories by allocating PHD grants. NSFA supports different national and international actions or educational programs for prevention of atherosclerosis. The society is also involved in the diffusion of information, research programs and clinician education by organizing seminars, conferences and workshops. The next annual meeting of the society will be held in Biarritz, June 19-21, 2014 Randox Cardiology 55 Diamond Road, Crumlin, Co. Antrim BT29 4QY Northern Ireland, UK www.randox.com Randox are an international clinical diagnostics company based in Northern Ireland, with a presence in over 150 countries worldwide. Cardiovascular disease is a key area of focus for Randox and we offer a huge range of relevant products, both for clinical research and clinical practice. Such products include automated clinical chemistry assays for Lp(a), sdLDL, Heart-type Fatty Acid Binding Protein (H-FABP), aspirin resistance, lipids and anti-oxidants. In addition to these is Randox’s pioneering multiplexing platforms, utilising the revolutionary Biochip Array Technology. Arrays available include cytokines, adhesion molecules, cardiac, cerebral & metabolic biomarkers. Regeneron 777 Old Saw Mill River Road Tarrytown NY 10591 USA www.regeneron.com Regeneron is a fully integrated biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron markets two products, ARCALYST® (rilonacept) Injection For Subcutaneous Use and EYLEA™ (aflibercept) Injection. Regeneron also has completed several Phase 3 studies and is conducting an additional Phase 3 clinical trial for the product candidate ZALTRAP® (aflibercept) Concentrate for Intravenous Infusion. Additional therapeutic candidates developed from proprietary Regeneron technologies for creating fully human monoclonal antibodies are in development programs in rheumatoid arthritis and other inflammatory conditions, pain, cholesterol reduction, allergic and immune conditions, and cancer XXXVI Roche Grenzacherstrasse 124 4070 Switzerland www.roche.com Headquartered in Basel, Switzerland, Roche is a leader in research-focused healthcare with combined strengths in pharmaceuticals and diagnostics. Roche is the world’s largest biotech company with truly differentiated medicines in oncology, virology, inflammation, metabolism and CNS. Roche is also the world leader in in-vitro diagnostics, tissue-based cancer diagnostics and a pioneer in diabetes management. Roche’s personalized healthcare strategy aims at providing medicines and diagnostic tools that enable tangible improvements in the health, quality of life and survival of patients. For more information: www.roche.com Sanofi 174 avenue de France 75635 Paris Cedex 13 France www.sanofi.com Sanofi, a global and diversified healthcare leader, discovers, develops and distributes therapeutic solutions focused on patients’ needs. Sanofi has core strengths in the field of healthcare with seven growth platforms: diabetes solutions, human vaccines, innovative drugs, rare diseases, consumer healthcare, emerging markets and animal health. Sanofi is listed in Paris (EURONEXT: SAN) and in New York (NYSE: SNY). Unilever www.unilever.com Make sustainable living commonplace Unilever’s purpose is to make sustainable living commonplace. We help people feel good, look good and get more out of life with brands and services that are good for them and good for others. 160 million times a day, in 190 countries, people use our home, personal care and foods products at key moments of their day. We produce world-leading brands including Lipton, Knorr, Hellmann’s, Becel/Flora, Ben & Jerry’s, Dove, Axe, and Omo. Wisepress Medical Bookshop 25 High Path, Merton Abbey London, SW19 2JL UK www.wisepress.com Wisepress.com, Europe’s leading conference bookseller, has a complete range of books and journals relevant to the themes of the meeting. Books can be purchased at the stand or, if you would rather not carry them, posted to you – Wisepress will deliver worldwide. In addition to attending 200 conferences per year, Wisepress has a comprehensive medical and scientific bookshop online with great offers. XXXVII 81 st Congress of the European Atherosclerosis Society • 2 – 5 June 2013 • Lyon, France Satellite Symposium Sponsored by MSD CETP Inhibition: What’s New? Sunday, 2 June 2013 15:15 – 16:00 MODERATOR: Lyon Convention Center Hall D Lyon, France M. John Chapman Director Emeritus , INSERM Past- President, EAS Research Professor Pitie-Salpetriere University Hospital Paris, France Moderator: John Chapman (France) FACULTY: Henry Ginsberg Irving Professor of Medicine Columbia University College of Physicians and Surgeons Director, Irving Institute for Clinical and Translational Research Columbia University Medical Center New York, New York, USA John Millar Director Metabolic Tracer Resource Institute for Diabetes, Obesity and Metabolism University of Pennsylvania Philadelphia, Pennsylvania, USA AGENDA Sunday, 2 June 2013 15:15 – 15:20 Introduction 15:20 – 15:35 HDL and CETP Metabolism Henry Ginsberg 15:35 – 15:50 Apo B and PCSK9 Kinetics John Millar 15:50 – 16:00 Q&A/Conclusion John Chapman John Chapman Copyright © 2013 Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., Whitehouse Station, NJ, USA. All rights reserved. CVT-177134-AB SCIENTIFIC PROGRAMME SUNDAY, JUNE 2, 2013 Clinical advances in difficult-to-treat patients with hypercholesterolemia 13:00–14:30, Monday, 3 June 2013 81st European Atherosclerosis Society Congress Claude Bernard Hall Lyon Congress Centre, Lyon, France Agenda 13:00 Introduction and welcome Michel Farnier and Christie M. Ballantyne (Co-Chairs) 13:05 The spectrum of difficult-to-treat hypercholesterolemic patients Christie M. Ballantyne 13:30 New and emerging LDL-C lowering therapies – Targeting production Erik S. G. Stroes 13:55 Emerging LDL-C lowering therapies – Targeting clearance Michel Farnier 14:20 Panel discussion M. John Chapman (Moderator) and all faculty 14:30 © 2013, Sanofi and Regeneron Pharmaceuticals, Inc. 5/2013 PCS-0184 GLB.ALI.13.05.01 Close of symposium Sunday, June 2, 2013 11:00-20:30 Registration Area REGISTRATION DESK OPEN 13:30-15:00 Forum 1: Claude Bernard EBAC ACCREDITED EDUCATIONAL PROGRAMME ADVANCES IN THE UNDERSTANDING OF CARDIOVASCULAR DISEASE AND DYSLIPIDAEMIA IN DIABETES Supported by an Unrestricted Educational Grant from AstraZeneca Programme created in collaboration with Sahlgrenska Academy, University of Gothenburg Chairperson: Olov Wiklund Time 13:30 INTRODUCTION Olov Wiklund, Sweden 13:35 CHARACTERISTICS OF THE VASCULAR LESION IN DIABETES Peter Libby, USA 14:00 LIPID METABOLISM AND CARDIOVASCULAR DISEASE IN DIABETES Marja-Riitta Taskinen, Finland 14:20 RISK OF DIABETES DEVELOPMENT DURING STATIN TREATMENT Naveed Sattar, UK 14:40 CURRENT TREATMENT OF DYSLIPIDAEMIA IN PATIENTS WITH THE METABOLIC SYNDROME AND DIABETES Børge Nordestgaard, Denmark 14:55 DISCUSSION Olov Wiklund, Sweden 1 Sunday, June 2, 2013 14:15-15:00 Forum 2: Marcel Mérieux HYPERCHOLESTEROLEMIA – WHAT CAN WE DO FOR HIGH-RISK PATIENTS? SPONSORED BY AMGEN Chairperson: Alberico L. Catapano Time 14:15 INTRODUCTION Alberico L. Catapano, Italy 14:20 HYPERCHOLESTEROLEMIA - WHAT CAN WE DO FOR HIGH-RISK PATIENTS? G. Kees Hovingh, The Netherlands 14:50 Q&A AND CLOSE Alberico L. Catapano, Italy 15:15-16:00 Forum 3: Michel Macheboeuf CETP INHIBITION: WHAT'S NEW? SPONSORED BY MSD Chairperson: M. John Chapman Time 15:15 INTRODUCTION M. John Chapman, France 15:20 HDL AND CETP METABOLISM Henry Ginsberg, USA 15:35 APO B AND PCSK9 KINETICS John Millar, USA 15:50 Q&A/CONCLUSION M. John Chapman, France 2 Sunday, June 2, 2013 16:20-17:50 Forum 3: Michel Macheboeuf NEW STRATEGIES FOR THE MANAGEMENT OF PATIENTS WITH HoFH SPONSORED BY AEGERION Chairpersons: Alberico L. Catapano Børge Nordestgaard Time 16:20 WELCOME Børge Nordestgaard; A.L. Catapano, Denmark, Italy 16:25 WHAT ARE WE ABLE TO ACHIEVE FOR OUR PATIENTS TODAY? Raul D. Santos, Brazil 16:50 EAS/ESC RECOMMENDATIONS FOR THE MANAGEMENT OF PATIENTS WITH HoFH Eric Bruckert, France 17:15 LOMITAPIDE IN THE MANAGEMENT OF HoFH - CLINICAL EXPERIENCE Marina Cuchel, USA 3 Sunday, June 2, 2013 18:00-19:30 Auditorium Anitschkow OPENING CEREMONY, INCLUDING THE ANITSCHKOW LECTURE Chairpersons: Alberico L. Catapano Philippe Moulin Time 18:00 WELCOME FROM THE EAS PRESIDENT Alberico L. Catapano, Italy 18:10 WELCOME FROM THE PRESIDENT OF THE CLAUDE BERNARD LYON1 UNIVERSITY François N. Gilly, France 18:13 WELCOME FROM THE NFSA PRESIDENT Michel Krempf, France 18:16 IAS AND EAS WORKING TOGETHER Philip Barter, Australia 18:19 WELCOME FROM THE CONGRESS CHAIRPERSON Philippe Moulin, France 18:22 Choir 18:30 INTRODUCTION OF THE ANITSCHKOW PRIZE WINNER Alberico L. Catapano, Italy 18:35 THE ANITSCHKOW LECTURE Peter Libby, USA 19:25 Choir 19:30-20:30 Exhibition Area WINE AND CHEESE WELCOME RECEPTION 4 SCIENTIFIC PROGRAMME MONDAY, JUNE 3, 2013 81st Congress of the European Atherosclerosis Society 2 – 5 June 2013 • Lyon, France Satellite Symposium Sponsored by MSD On The Forefront of CHOLESTEROL MANAGEMENT: Clinical Considerations and Practical Approaches Beyond Statins Monday, 3 June 2013 CHAIRMAN: 17:00 – 18:30 Lyon Convention Center Hall A Lyon, France Alberico L. Catapano President EAS Professor of Pharmacology Director, SISA Center for the Study of Atherosclerosis Director, Center of Epidemiology and Preventive Pharmacology Director, Laboratory of Lipoproteins and Atherosclerosis Department of Pharmacological and Biomolecular Sciences University of Milan Milan, Italy FACULTY: Philip Barter President, International Atherosclerosis Society Conjoint Professor The University of New South Wales Sydney, Australia John E. Deanfield BHF Vandervell Chair of Congenital Heart Disease Director, Centre for Cardiovascular Prevention & Outcomes Deputy Cardiovascular Program Director, UCL Partners London, United Kingdom Chairman: Alberico Catapano (Italy) AGENDA Monday, 3 June 2013 17:00 – 17:05 Chair Welcome and Opening Remarks Alberico Catapano 17:05 – 17:25 Unmet Medical Needs in Dyslipidemia Philip Barter 17:25 – 17:45 Achieving Superior Efficacy by intensive LDL-C lowering; Arguments for the use of a cholesterol absorption inhibitor Michel Farnier 17:45 – 18:05 Improving Clinical Outcomes in Statin Treated Patients John Deanfield 18:05 – 18:25 Panel Discussion Alberico Catapano Philip Barter Michel Farnier 18:25 – 18:30 Closing Remarks Alberico Catapano Michel Farnier Department of Endocrinology and Lipidology Point Medical Clinic Dijon, France Copyright © 2013 Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., Whitehouse Station, NJ, USA. All rights reserved. CVT-176000-AB Monday, June 3, 2013 08:30-10:30 Auditorium Anitschkow PLENARY SESSION: PLAQUE INSTABILITY AND ATHEROTHROMBOSIS Chairpersons: Alberico L. Catapano Lale Tokgozoglu Time 08:30 BIOMARKERS OF PLAQUE OF INSTABILITY Jean-Baptiste Michel, France 09:00 NEW INSIGHTS INTO THE ROLE OF HEMODYNAMICS IN PLAQUE INSTABILITY Yiannis Chatzizisis, Greece 09:30 ADVANCES IN VISUALIZING THE UNSTABLE PLAQUE Filippo Crea, Italy 10:00 PREVENTION AND TREATMENT OF PLAQUE THROMBOGENICITY Gilles Montalescot, France 10:30-10:50 Exhibition Area COFFEE BREAK, POSTER VIEWING AND EXHIBITION 10:50-12:40 Auditorium Anitschkow ADVANCED CLINICAL SEMINAR EVALUATION AND MANAGEMENT OF LOW HDL: WHY AND HOW? Chairpersons: Anne Tybjaerg-Hansen Sebastiano Calandra Time 10:50 GENETIC AND NON-GENETIC FACTORS AFFECTING HDL LEVELS AND FUNCTIONS Dimitris Kardassis, Greece 11:20 WHAT IS THE MESSAGE FROM INTERVENTION STUDIES? Klaus Parhofer, Germany 11:50 HDL AND REVERSE CHOLESTEROL TRANSPORT: HOW TO PROCEED? Erik Stroes, The Netherlands 5 Monday, June 3, 2013 10:50-12:40 Forum 1: Claude Bernard REGULATION OF CELLULAR LIPID METABOLISM IN ATHEROGENESIS Chairpersons: Vesa M Olkkonen Marcello Arca Time 10:50 OXYSTEROL-BINDING PROTEINS: EMERGING FUNCTIONS IN CELL REGULATION AND ATHEROGENESIS Vesa M. Olkkonen, Finland 11:15 PPARS, NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD) AND ATHEROSCLEROSIS Bart Staels, France Abstract No 11:40 TRANS INTESTINAL CHOLESTEROL EXCRETION IS AN ACTIVE METABOLIC PROCESS MODULATED BY PCSK9 AND STATIN, INVOLVING ABCB1 Jean Mathieu Berger, C. Le May, B. Pillot, J. Magré, X. Prieur, E. Letessier, B. Cariou1,2, P. Costet1,2, France 1037 11:55 IDENTIFICATION OF AN ENDOGENOUS PROTEIN WHICH BLOCKS THE INTERACTION BETWEEN OXLDL AND ITS RECEPTORS Akemi Kakino, Y. Fujita, T. Sawamura, Japan 1471 12:10 MYELOID CELL-SPECIFIC SERINE PALMITOYLTRANSFERASE SUBUNIT 2 HAPLOINSUFFICIENCY REDUCES ATHEROSCLEROSIS IN MICE M. Chakraborty, C. Lou, M.-S. Kuo, G. Cao, Xian-Cheng Jiang, USA 185 12:25 AGGREGATED LDL INDUCES LRP1 PROTEIN STABILIZATION THROUGH E3 UBIQUITIN-LIGASE CHFR DOWNREGULATION IN HUMAN VSMC R. Cal, M. Garcia-Arguinzonis, E. Revuelta-Lopez, J. Castellano, T. Padro, L. Badimon, Vicenta Llorente-Cortes, Spain 6 473 Monday, June 3, 2013 10:50-12:40 Forum 2: Marcel Mérieux EVALUATION AND TREATMENT OF CARDIOVASCULAR RISK FACTORS IN THE YOUNG AND THE ELDERLY Chairpersons: George Davey-Smith Michel Krempf Time 10:50 IS THERE AN UPPER AGE LIMIT FOR LIPID LOWERING IN CARDIOVASCULAR PREVENTION? Olov Wiklund, Sweden 11:15 EPIDEMIOLOGICAL METHODS TO IDENTIFY STRENGTH OF CAUSAL ASSOCIATIONS BETWEEN RISK FACTORS AND CARDIOVASCULAR OUTCOMES George Davey-Smith, UK Abstract No. 11:40 ELEVATED REMNANT CHOLESTEROL CAUSES LOW-GRADE INFLAMMATION AND ISCHEMIC HEART DISEASE Anette Varbo, M. Benn, A. Tybjærg-Hansen, B.G. Nordestgaard, Denmark 985 11:55 COMBINED EFFECTS OF CHILD AND ADULT ELEVATED BLOOD PRESSURE ON SUBCLINICAL ATHEROSCLEROSIS. THE INTERNATIONAL CHILDHOOD CARDIOVASCULAR COHORT CONSORTIUM Markus Juonala, J. Juhola, C.G. Magnussen, M.A. Sabin, T. Dwyer, A. Venn, T.L. Burns, G.S. Berenson, M. Kähönen, J.S. Viikari, S.R. Daniels, O.T. Raitakari, Finland, Australia, USA 12:10 12:25 SOCIOECONOMIC POSITION AND TRUNCAL FAT INFLUENCE CAROTID INTIMA-MEDIA THICKNESS IN ADOLESCENTS: THE HELENA STUDY Christophe Lamotte, C. Iliescu, L. Beghin, J. Salleron, S. De Henauw, L.A. Moreno, C. Libersa, F. Gottrand, France, Belgium, Spain 336 1480 SERUM LEVELS OF DEHYDROEPIANDROSTERONE (DHEA) AND ITS SULFATE (DHEA-S) PREDICT THE FIVE YEAR RISK OF CARDIOVASCULAR EVENTS IN ELDERLY MEN Åsa Tivesten, M. Nilsson, D. Carlzon, L. Vandenput, M.K. Karlsson, Ö. Ljunggren, E. Barrett-Connor, D. Mellström, C. Ohlsson, Sweden, USA 875 7 Monday, June 3, 2013 10:50-12:40 Forum 3: Michel Macheboeuf ENDOTHELIAL DYSFUNCTION IN ATHEROTHROMBOSIS Chairpersons: Qingbo Xu Erik Stroes Time 10:50 ENDOTHELIAL REPAIR BY STEM CELLS Qingbo Xu, UK 11:15 ROLE OF ENDOTHELIAL MICRORNAS IN VASCULAR DISEASE Andreas M. Zeiher, Germany 11:40 ADRENOMEDULLIN IS ASSOCIATED TO ARTERIAL STIFFNESS: AN INTEGRATIVE APPROACH COMBINING MONOCYTE ADM EXPRESSION, PLASMA MR-PROADM AND GENOME-WIDE ASSOCIATION STUDY Farzin Beygui1,2, P.S. Wild, T. Zeller, M. Germain, R. Castagné, T. Münzel, G. Montalescot2,5, D.-A. Trégouët, F. Cambien, S. Blankenberg, L. Tiret, France, Germany 553 11:55 HEDGEHOG PATHWAY AGONISM AMELIORATES DYSFUNCTION OF VASCULAR ENDOTHELIUM IN OBESITY: ROLE OF PHOSPHATIDYLINOSITOL-3-KINASE AND ENDOTHELIUM NITRIC OXIDE SYNTHATASE Saurabh Sharma, P.L. Sharma, India 365 12:10 THE RNA-BINDING PROTEIN QUAKING MAINTAINS ENDOTHELIAL BARRIER FUNCTION THROUGH TARGETING VE-CADHERIN MRNA Janine M. van Gils, R.G. de Bruin, I. Schmidt, E.P. van der Veer, M.K. Roeten, T.J. Rabelink, A.J. van Zonneveld, The Netherlands Abstract No. 12:25 1035 PLASMA ASYMMETRIC DIMETHYLARGININE, ENDOTHELIUMDEPENDENT NITRIC OXIDE-MEDIATED RELAXATION AND VASCULAR REMODELING OF UTERINE SMALL ARTERIES IN PREGNANT WOMEN Malene Rohr Andersen, U. Simonsen, S. Stender, M. Hedegaard, C. Aalkjær, Denmark 1518 12:40-14:45 Exhibition Area LUNCH BREAK, EXHIBITION AND POSTER PRESENTATIONS 13:40 – 14:40 MODERATED POSTER SESSION A (See page 29) 8 Monday, June 3, 2013 12:50-13:40 Forum 2: Marcel Mérieux EAS GENERAL ASSEMBLY 13:00-14:30 Forum 1: Claude Bernard CLINICAL ADVANCES IN DIFFICULT-TO-TREAT PATIENTS WITH HYPERCHOLESTEROLEMIA SPONSORED BY SANOFI / REGENERON / GENZYME Chairpersons: Michel Farnier Christie Ballantyne Time 13:00 INTRODUCTION AND WELCOME C. Ballantyne; M. Farnier, USA, France 13:05 THE SPECTRUM OF DIFFICULT-TO-TREAT HYPERCHOLESTEROLEMIC PATIENTS C. Ballantyne, USA 13:30 NEW AND EMERGING LDL-C-LOWERING THERAPIES - TARGETING PRODUCTION Erik Stroes, The Netherlands 13:55 EMERGING LDL-C-LOWERING THERAPIES - TARGETING CLEARANCE Michel Farnier, France 14:50-16:40 Auditorium Anitschkow JOINT ICCR/EAS SYMPOSIUM: LIFESTYLE FACTORS AND CARDIOVASCULAR DISEASES Chairpersons: Marja-Riitta Taskinen Frank Hu Time 14:50 OPENING REMARKS 15:00 TARGETING HEALTHY DRINKING FOR CVD RISK REDUCTION Frank Hu, USA 15:25 PHYSICAL ACTIVITY AND CVD RISK MANAGEMENT Robert Ross, Canada 15:50 ECTOPIC FAT AS A NEW TARGET FOR CVD RISK MANAGEMENT Marja-Riitta Taskinen, Finland 16:15 EVOLVING MOSAIC OF MODIFIABLE CVD RISK FACTORS Luc Van Gaal, Belgium 9 Monday, June 3, 2013 14:50-16:40 Forum 1: Claude Bernard ROLE OF LIPASES IN LIPID AND LIPOPROTEIN METABOLISM Chairpersons: Sander Kersten Matti Jauhiainen Time 14:50 REGULATION OF PLASMA TRIGLYCERIDE CLEARANCE BY ANGIOPOIETIN-LIKE PROTEINS Sander Kersten, The Netherlands 15:15 THE COMPLEXITY OF LPL ACTION IN TG METABOLISM Geesje Dallinga-Thie, The Netherlands Abstract No 15:40 LOSS-OF-FUNCTION MUTATION IN THE ANGPTL3 GENE IS ASSOCIATED WITH INCREASED LPL ACTIVITY AND DECREASED SERUM FREE FATTY ACIDS Matti Jauhiainen, M. Robciuc, A. Lahikainen, A. Bensadoun, D. Rader, M. Maranghi, K. Öörni, I. Minicocci, M. Arca, C. Ehnholm, Finland, USA, Italy 56 15:55 NOVEL SMALL MOLECULE LIPOPROTEIN LIPASE ACTIVATOR LP071 IMPROVES PLASMA LIPID PARAMETERS IN VIVO M. Eriksson, M. Larsson, R. Caraballo, P.-A. Enquist, M. Elofsson, G. Olivecrona, Stefan K Nilsson, Sweden 304 16:10 EXPRESSION OF GROUP IIA SECRETORY PHOSPHOLIPASE A2 (SPLA2) INHIBITS CHOLESTERYL ESTER TRANSFER PROTEIN (CETP) ACTIVITY IN TRANSGENIC MICE E. Hurt-Camejo, T. Gautier, B. Rosengren, M. Behrendt, D.S. Grass, D.J. Rader, Uwe J.F. Tietge, Sweden, France, USA, The Netherlands 235 16:25 MULTIPLE MOLECULAR DEFECTS ASSOCIATED TO NOVEL APOA5 MUTATIONS FOUND IN PATIENTS WITH SEVERE HYPERCHYLOMICRONEMIA Josep Julve1,2, E. Mendoza-Barberà, S.K. Nilsson, A. Lookene, J.M. MartínCampos, R. Roig2,5, A.M. Lechuga-Sancho, J.J. Sloan, P. Fuentes-Prior, F. 594 Blanco-Vaca2,5,8, Spain, Sweden, Estonia, USA 10 Monday, June 3, 2013 14:50-16:40 Forum 2: Marcel Mérieux CELLULAR GROWTH, DEATH, TRAFFICKING, AND MICROVESICULATION IN ATHEROGENESIS Chairperson: Wolfgang Schneider Edward Fisher Time 14:50 MACROPHAGE PHENOTYPIC DIVERSITY DURING ATHEROSCLEROSIS REGRESSION Edward Fisher, USA 15:15 MATRIX VESICLES RELEASED BY SMOOTH MUSCLE CELLS: KEY INITIATORS OF VASCULAR CALCIFICATION Catherine. M. Shanahan, UK Abstract No 15:40 CARTILAGENOUS METAPLASIA IN ATHEROSCLEROSIS IS ASSOCIATED WITH TRAIL-DEFICIENCY AND ALTERED EXPRESSION OF GENES INVOLVED IN CALCIFICATION B. Di Bartolo, S. Cartland, H. Harith1,2, M. Schoppet, Mary Kavurma1,2, Australia, Germany 938 15:55 TARGETING CHONDROITIN SULFATE NACETYLGALACTOSAMINYLTRANSFERASE 2 IN THE MODIFICATION OF SUBENDOTHELIAL LIPOPROTEIN RETENTION AND FOAM CELL FORMATION Dyah Samti Mayasari, N. Emoto1,2, K. Yagi, K. Nakayama, N. Arfian, H. Ali, K.-I. Hirata, Japan 16:10 16:25 NOTCH PATHWAY POLARIZES MONOCYTES INTO M2 MACROPHAGES AND INHIBITS ATHEROSCLEROSIS IN APOE KNOCKOUT MICE Dinender Singla, B. Yan, L. Abdeli, S. Parthasarathy, USA + 904 1091 NULL T CELLS FROM PATIENTS WITH MYOCARDIAL CD4 CD28 INFARCTION HAVE DEREGULATED APOPTOSIS PATHWAYS AND ARE RESISTANT TO APOPTOTIC CELL DEATH Ingrid Elena Dumitriu, E. Kovalcsik, R. Antunes, J.C. Kaski, UK 11 1464 Monday, June 3, 2013 15:45-16:30 Forum 3: Michel Macheboeuf EAS INITIATIVES UPDATE OVERVIEW OF CURRENT STATUS AND FORTHCOMING DEVELOPMENTS IN THE SOCIETY’S KEY INITIATIVES Chairpersons: Alberico L. Catapano Lale Tokgozoglu Time 15.45 INTRODUCTION BY SESSION CHAIRS Alberico L. Catapano, Lale Tokgozoglu 15.50 EAS GUIDELINES AND CONSENSUS PAPERS INITIATIVE Alberico L. Catapano 15.55 EAS CONSENSUS POSITION PAPER INITIATIVE – FOCUS ON FH Børge Nordestgaard 16.15 GLOBAL GUIDELINES Olov Wiklund 12 Monday, June 3, 2013 17:00-18:30 Auditorium Anitschkow ON THE FOREFRONT OF CHOLESTEROL MANAGEMENT: CLINICAL CONSIDERATIONS AND PRACTICAL APPROACHES BEYOND STATINS SPONSORED BY MSD Chairperson: Alberico L. Catapano Time 17:00 WELCOME AND OPENING REMARKS Alberico L. Catapano, Italy 17:05 UNMET MEDICAL NEEDS IN DYSLIPIDEMIA Philip Barter, Australia 17:25 ACHIEVING SUPERIOR EFFICACY BY INTENSIVE LDL-C LOWERING; ARGUMENTS FOR THE USE OF A CHOLESTEROL ABSORPTION INHIBITOR Michel Farnier, France 17:45 IMPROVING CLINICAL OUTCOMES IN STATIN TREATED PATIENTS John E. Deanfield, UK 18:05 PANEL DISCUSSION A.L. Catapano; P. Barter; M. Farnier; J.E. Deanfield, Italy, Australia, France, UK 18:25 CLOSING REMARKS Alberico L. Catapano, Italy 17:00-17:45 Forum 1: Claude Bernard SPECIAL LECTURE SPONSORED BY KOWA Chairperson: Yasushi Saito Time 17:00 INTRODUCTION TO KOWA SPECIAL LECTURE Yasushi Saito, Japan 17:05 NORMALISING DYSLIPIDEMIA AND REVERSING ATHEROSCLEROSIS IN CARDIO-METABOLIC DISEASE: INSIGHTS FROM STATIN PHARMACOTHERAPY M. John Chapman, France 13 Monday, June 3, 2013 17:00-17:50 Forum 3: Michel Macheboeuf THE ROLE OF PLANT STANOLS/STEROLS IN THE MANAGEMENT OF DYSLIPIDAEMIAS JOINTLY SPONSORED BY BASF, DANONE, RAISIO, UNILEVER Chairpersons: Henry Ginsberg Petri Kovanen Time 17:00 INTRODUCTION AND OPENING REMARKS Henry Ginsberg, USA 17:05 BASIC SCIENCE OF PLANT STEROLS/STANOLS Jogchum Plat, The Netherlands 17:25 CLINICAL APPLICATION & SAFETY OF PLANT STEROLS/STANOLS Henry Ginsberg, USA 17:45 SUMMARY AND CLOSING REMARKS Petri Kovanen, Finland 14 SCIENTIFIC PROGRAMME TUESDAY, JUNE 4, 2013 Tuesday, June 4, 2013 08:30-10:30 Auditorium Anitschkow PUSHING THE FRONTIERS IN CARDIOVASCULAR BIOLOGY Chairpersons: Philippe Moulin Olov Wiklund Time 08:30 GUT-LIVER INTERACTION IN TRIGLYCERIDE RICH LIPOPROTEIN METABOLISM Gary Lewis, Canada 09:00 MICRO-RNA AND EPIGENETIC CONTROL OF ATHEROGENESIS Kathryn Moore, USA 09:30 THERAPEUTIC OPTIONS TO INDUCE REGRESSION OF CORONARY ATHEROSCLEROSIS Steven Nissen, USA 10:00 PHARMACOLOGICAL TARGETS IDENTIFIED BY GENETIC APPROACHES François Cambien, France 10:30-10:50 Exhibition Area COFFEE BREAK, POSTER VIEWING AND EXHIBITION 10:50-12:40 Auditorium Anitschkow ADVANCED CLINICAL SEMINAR: WHEN STATINS ARE NOT TOLERATED OR ARE NOT SUFFICIENT ALONE: HOW TO HANDLE THE PROBLEM? Time 10:50 PATIENTS NOT AT GOAL: WHAT ARE THE CAUSES? Eric Bruckert, France 11:15 WHAT IS THE ROOM FOR THE ASSOCIATION THERAPY Marcello Arca, Italy 11:40 LOWERING LDL-CHOLESTEROL -BEYOND STATIN THERAPY Frederick Raal, South Africa 15 Tuesday, June 4, 2013 10:50-12:40 Forum 1: Claude Bernard HEPATIC REGULATION OF LIPID AND LIPOPROTEIN METABOLISM IN CARDIOMETABOLIC DISORDERS Chairpersons: Marten Hofker Maurizio Averna Time 10:50 DERANGEMENT OF HEPATIC LIPID METABOLISM Jan Boren, Sweden 11:15 MACROPHAGES LINK FATTY LIVER DISEASE AND ATHEROSCLEROSIS Marten Hofker, The Netherlands Abstract No 11:40 P2Y13 RECEPTOR DEFICIENCY DECREASES HEPATOBILIARY AND FAECAL LIPID EXCRETIONS AND PROMOTES ATHEROSCLEROSIS IN APOE KNOCKOUT MICE Laeticia Lichtenstein, N. Serhan, B. Perret, M. Laffargue, L.O. Martinez, France 1486 11:55 NAFLD AND CARDIOVASCULAR DISEASE: MAY A SUFFERING LIVER BE A PREDICTOR MARKER OF CARDIOVASCULAR RISK? Carmela Viscomi1,2, A. Minutolo, M. Arciello, B. Conti, R. Maggio, A. Longo, 609 E. Scarpellini, C. Balsano2,4, Italy 12:10 EXENDIN-4 REDUCES THE DEVELOPMENT OF NON-ALCOHOLIC STEATOHEPATITIS IN ADDITION TO ATHEROSCLEROSIS IN APOE*3LEIDEN.CETP MICE Yanan Wang, E.T. Parlevliet1,2, J.J. Geerling, S.J.L. van der Tuin, V. Bieghs, A.H.M. Jawad, H. Zhang, R. Shiri-Sverdlov, L.M. Havekes1,4,5, J.A. Romijn1,2, 524 K. Willems van Dijk1,6, P.C.N. Rensen, The Netherlands 16 Tuesday, June 4, 2013 10:50-12:40 Forum 2: Marcel Mérieux LIFESTYLE FACTORS AND CARDIOVASCULAR DISEASES Chairpersons: Adrian JB Brady Zeljko Reiner Time 10:50 DIET AND CARDIOVASCULAR RISK: EVIDENCE AND POSSIBLE MECHANISMS Angela Rivellese, Italy 11:15 DIET AND EXERCISE - JUST A BIG WASTE OF TIME? Adrian J. Brady, UK Abstract No. 11:40 CHROMOSOME 9P21 VARIANT INTERACTS WITH DIETARY VEGETABLE AND WINE INTAKE ON THE RISK OF CARDIOVASCULAR DISEASE George Hindy, V. Hamrefors, U. Ericson, I. Drake, E. Wirfält, O. Melander, M. Orho-Melander, Sweden 1361 11:55 EFFECT OF DIFFERENT EXERCISE MODALITIES IN EXPERIMENTAL PERIPHERAL ARTERY DISEASE AND ASSESSMENT OF POTENTIAL UNDERLYING MECHANISMS Maxime Pellegrin, K. Bouzourene, C. Poitry-Yamate, V. Mlynarik, J.-F. Aubert, C. Amstutz, R. Gruetter, L. Mazzolai, Switzerland 12:10 INCREASING LONG-CHAIN N-3PUFA CONSUMPTION IMPROVES SMALL PERIPHERAL ARTERY FUNCTION IN PATIENTS AT INTERMEDIATE-HIGH CARDIOVASCULAR RISK Jordi Merino, A. Sala-Vila, R. Kones, R. Ferré, N. Plana, J. Girona, D. Ibarretxe, M. Heras, E. Ros, L. Masana, Spain, USA 17 617 1318 Tuesday, June 4, 2013 10:50-12:40 Forum 3: Michel Macheboeuf INFECTION, INFLAMMATION AND IMMUNITY IN ATHEROGENESIS Chairpersons: Eicke Latz Michal Vrablík Time 10:50 MOLECULAR REGULATION OF MACROPHAGES: IMPLICATIONS FOR ATHEROSCLEROSIS Menno P.J. De Winther, The Netherlands 11:15 CHOLESTEROL CRYSTALS AS A DANGER SIGNAL IN ATHEROSCLEROSIS Eicke Latz, Germany Abstract No. + 11:40 CYTOTOXIC CD8 T CELLS PROMOTE VULNERABLE ATHEROSCLEROTIC PLAQUE DEVELOPMENT IN APOE-/- MICE T. Kyaw, C. Tay, A. Winslop, P. Kanellakis, H. Hosseini, A. Cao, A. Bobik, P. Tipping, Ban-Hock Toh, Australia 175 11:55 METAGENOMICS REVEALS GUT SIGNATURES IN ATHEROSCLEROSIS MICROBIOME Emi Kozarov1,2, S. Kalachikov, A. Morozov, N. Chalmers4,5, M. Chien, Spain, USA 758 12:10 THE NEUTROPHIL ACTIVATION MARKER MRP8/14 CORRELATES WITH CAROTID PLAQUE AREA AND PREDICTS CARDIOVASCULAR EVENTS IN HEALTHY INDIVIDUALS O. Cotoi, N. Ko, P. Dunér, H. Björkbacka, J. Nilsson, Alexandru Schiopu2,3, Romania, Sweden 1068 12:25 OPTIMIZING NATURAL OCCURRING IGM ANTIBODIES FOR THERAPEUTIC USE: INFLAMMATORY VASCULAR DISEASE TREATMENT WITH ANTI-PHOSPHORYLCHOLINE IGG M.M. Ewing, J.C. Karper, M.R. De Vries, R.C.M. de Jong, I. Dahlbom, J. Kuiper, S. Karabina, E. Ninio, J.W. Jukema, K. Pettersson, Paul Quax, The Netherlands, Sweden, France 1023 12:40-14:45 Exhibition Area LUNCH BREAK, EXHIBITION AND POSTER PRESENTATIONS 12:40 – 13:40 MODERATED POSTER SESSION B (See page 37) 13:40 – 14:40 MODERATED POSTER SESSION C (See page 47) 18 Tuesday, June 4, 2013 13:00-14:30 Auditorium Anitschkow CONTEXT AND FUTURE CHALLENGES IN THE EFFECTIVE MANAGEMENT OF DYSLIPIDAEMIA SPONSORED BY ROCHE Chairpersons: Chris Packard Terje Pedersen Alberico L. Catapano Time 13:00 INTRODUCTION Terje Pedersen, Norway 13:05 LDL CHOLESTEROL AND CARDIOVASCULAR RISK REDUCTION SUCCESSES AND CHALLENGES Lale Tokgozoglu, Turkey 13:30 PCSK9 INHIBITION, A SAFE AND EFFICIENT STRATEGY TO LOWER LDL CHOLESTEROL? Gilles Lambert, France 13:55 TRANSLATING NEW APPROACHES TO REDUCE LDL CHOLESTEROL INTO FUTURE THERAPIES Evan Stein, USA 14:20 SUMMARY AND CLOSE Chris Packard, UK 19 Tuesday, June 4, 2013 14:50-16:40 Forum 1: Claude Bernard CARDIOVASCULAR DISEASE AND ITS PREVENTION IN PATIENTS WITH CHRONIC INFLAMMATORY OR CHRONIC KIDNEY DISEASE Chairpersons: Eric Bruckert Naveed Sattar Time 14:45 CARDIOVASCULAR DISEASE AND IT'S PREVENTION IN PATIENTS WITH CHRONIC INFLAMMATORY MUSCULOSKELETAL DISEASES George D. Kitas, UK 15:10 CARDIOVASCULAR DISEASE AND IT'S PREVENTION IN PATIENTS WITH CHRONIC INFLAMMATORY MUSCULOSKELETAL DISEASES Naveed Sattar, UK Abstract No. 15:35 IMPACT OF MILD CHRONIC KIDNEY DISEASE ON CORONARY ATHEROSCLEROSIS, CARDIAC SYSTOLIC FUNCTION AND MORTALITY Andrea Natali, B. Boldrini, S. Baldi, M. Rossi, A. L'Abbate, E. Ferrannini, Italy 561 15:50 INHIBITION OF MATRIX METALLOPROTEINASE-9 ATTENUATES DIABETIC NEPHROPATHY BY MODULATING PODOCYTE FUNCTIONS AND DOWNREGULATION EPITHELIAL-MESENCHYMAL TRANSITION Po-Hsun Huang, S.-Y. Li, S.-J. Lin, Taiwan R.O.C. 352 16:05 ATHEROPROTECTIVE CHANGES IN HDL COMPOSITION IN RHEUMATOID ARTHRITIS PATIENTS TREATED WITH TNF-INHIBITORS Johannes Levels, A. Jamnitski, I. van den Oever, M.T. Nurmohamed, The Netherlands 1404 16:20 LIPOPROTEIN(a) IS CAUSALLY ASSOCIATED WITH TYPE 2 DIABETES 1177 Pia R. Kamstrup1,2, B.G. Nordestgaard1,2, Denmark 20 Tuesday, June 4, 2013 14:50-16:40 Auditorium Anitschkow JOINT ESC/EAS SYMPOSIUM: BEHIND ENEMY LINES: IMMUNOMODULATION IN ATHEROSCLEROSIS Chairpersons: Christoph Binder Jan Nilsson Time 14:50 ANTIBODIES TO OXIDIZED LIPIDS Christoph Binder, Austria 15:15 CD31 PEPTIDES Giuseppina Caligiuri, France 15:40 ARTERY TERTIARY LYMPHOID ORGANS (ATLOS) CONTROL KEY STEPS OF ATHEROSCLEROSIS T CELL RESPONSES IN APOE-/- MICE DURING AGING Andreas Habenicht, Germany 16:05 VACCINES Jan Nilsson, Sweden 21 Tuesday, June 4, 2013 14:50-16:40 Forum 2: Marcel Mérieux LATE BREAKING SESSION Chairpersons: Geesje Dallinga-Thie Arnold von Eckardstein Time Abstract No. 14:50 THE SUSCEPTIBILITY OF LDL TO AGGREGATION DEPENDS ON LDL COMPOSITION Katariina Öörni, H. Lähteenmäki, T. Aittokallio, M. Jauhiainen, L. Rudel, P.T. Kovanen, Finland, USA 1650 15:05 VALIDATION OF A NEAR-INFRARED SPECTROSCOPIC SIGNATURE OF LIPID LOCATED AT CULPRIT LESIONS IN ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION David Erlinge, J.E. Muller, R. Puri, J. Harnek, M. Götberg, R. McNamara, D. Wohns, S. Vanoosterhout, K. Wolski, S. Madden, S. Nicholls, R.D. Madder, Sweden, USA, Australia 1637 15:20 PROTECTIVE EFFECTS OF PLANT STEROL AND STANOL ESTERS IN DIET-INDUCED NONALCOHOLIC STEATOHEPATITIS IN HYPERLIPIDEMIC MICE Jogchum Plat, V. Bieghs, T. Hendrikx, M. Jeurissen, S. Walenbergh, P.J. van Gorp, E.D. de Smet, M. Konings, A.C.E. Vreugdenhil, Y.D. Guichot, D. Lutjohann, R.P. Mensink, R. Shiri-Sverdlov, The Netherlands, Germany 1628 15:35 EFFECT OF Ω-3 FATTY ACID ETHYL ESTERS ON POSTPRANDIAL APOLIPOPROTEIN B-48 KINETICS IN OBESE SUBJECTS ON A WEIGHT LOSS DIET Dick C. Chan, A.T.Y. Wong, P.H.R. Barrett, G.F. Watts, Australia 1634 15:50 FIRST REPORT OF ENZYME REPLACEMENT THERAPY IN A PATIENT WITH FAMILIAL LCAT DEFICIENCY: RAPID IMPROVEMENT OF LIPID AND CLINICAL MANIFESTATIONS Robert Shamburek, R. Bakker-Arkema, B. Krause, B. Auerbach, L. Freeman, R. Homan, B. Asztalos, E. Schaefer, C. Schwartz, M. Amar, A. Remaley, USA 1635 16:05 NEW INSIGHTS INTO STATIN ACTION ON THE DYSLIPIDEMIA OF METABOLIC SYNDROME: NORMALISATION OF BIOACTIVE PLASMALOGENS AND SPHINGOLIPIDS IN HDL Peter J. Meikle, G. Wong, A.R. Tan, B.A. Kingwell, A.K. Orsoni, N. Hounslow, P. Giral, M.J. Chapman, Australia, France, UK 1643 TRIAL EVALUATING AMG 145, A PCSK9 ANTIBODY, IN PATIENTS WITH HOMOZYGOUS FH: RESULTS OF AN INITIAL DOSESCHEDULING STUDY Evan A. Stein, N. Honarpour, S.M. Wasserman, F. Xu, R. Scott, F. Raal, USA, South Africa 1625 16:20 22 Tuesday, June 4, 2013 14:50-15:35 Forum 3: Michel Macheboeuf YOUNG INVESTIGATOR AWARD SESSION Chairpersons: Petri Kovanen Danilo Norata Time 14:50 , 15:10 WINNER IN BASIC RESEARCH STEM CELL MOBILIZATION AND CHOLESTEROL EFFLUX Laurent Yvan-Charvet, France WINNER IN CLINICAL RESEARCH Y-CHROMOSOME AND CARDIOVASCULAR DISEASE Maciej Tomaszewski, UK 15:40-16:40 Forum 3: Michel Macheboeuf CLINICAL EXPERIENCE OF LOMITAPIDE THERAPY IN PATIENTS WITH HoFH DURING CLINICAL TRIALS SPONSORED BY AEGERION Chairperson: Raul D. Santos Time 15:40 SELECTING THE RIGHT PATIENTS WHO MAY BE SUITABLE FOR LOMITAPIDE THERAPY M. Averna; D. Blom, Italy, South Africa 16:00 PRACTICALITIES OF DRUG ADMINISTRATION INCLUDING DOSE TITRATION AND DRUG INTERACTIONS M. Averna; D. Blom, Italy, South Africa 16:20 MANAGEMENT AND MONITORRING OF ADVERSE EFFECTS M. Averna; D. Blom, Italy, South Africa 17:00-19:00 Forum 3: Michel Macheboeuf REVIEWER, AUTHOR WORKSHOP SPONSORED BY ELSEVIER 23 24 SCIENTIFIC PROGRAMME WEDNESDAY, JUNE 5, 2013 Wednesday, June 5, 2013 08:30-10:30 Auditorium Anitschkow LIPIDS AND LIPOPROTEINS: EMERGING RISK FACTORS AND THERAPIES Chairpersons: Marja-Riitta Taskinen M John Chapman Time 08:30 TAILORING TREATMENT ACCORDING TO LIPID PHENOTYPE Anton Stalenhoef,, The Netherlands 09:00 NEW INSIGHTS OBTAINED FROM LIPIDOMICS AS RISK MARKERS Robert Gerszten, USA 09:30 LIPID SIGNALING AND LIPOTOXICITY Rudolf Zechner, Austria 10:00 EMERGING THERAPEUTIC APPROACHES TO TREAT DYSLIPIDEMIAS Chris Packard, UK 10:30-10:50 Exhibition Area COFFEE BREAK, POSTER VIEWING AND EXHIBITION 10:50-11:40 Auditorium Anitschkow ADVANCED CLINICAL SEMINAR: CLINICAL UTILITY OF NON-INVASIVE IMAGING IN CVD RISK ASSESSMENT Chairperson: Jacques Bonnet Time 10:50 ASSESSMENT OF CORONARY ARTERY DISEASE BY COMPUTED TOMOGRAPHY IS BETTER Lale Tokgozoglu, Turkey 11:10 ASSESSMENT OF CAROTID ARTERY DISEASE BY ULTRASOUND AND MAGNETIC RESONANCE IMAGING IS BETTER Henrik Sillesen, USA 25 Wednesday, June 5, 2013 10:50-12:40 Forum 1: Claude Bernard PRIMARY AND FAMILIAL DYSLIPIDEMIAS Chairpersons: Vincent Durlach Jan A. Kuivenhoven Time 10:50 DYSLIPIDEMIA IN CHOLESTERYL ESTER STORAGE DISEASE Sebastiano Calandra, Italy 11:15 MOLECULAR GENETIC STUDIES IN PATIENTS WITH FAMILIAL HYPERCHOLESTREOLEMIA Jan A. Kuivenhoven, The Netherlands Abstract No. 11:40 A FOURTH TYPE OF AUTOSOMAL DOMINANT HYPERCHOLESTEROLEMIA CHARACTERIZED BY AN ALTERATION OF THE LDL ENDOSOMAL TRANSPORT Mathilde Varret, E. Girard, B. Védie, K. Ouguerram, A. Marques-Pinheiro, S. Lestavel, M. Guerin, Y. Zair, M. Devillers, M. Krempf, M. Abifadel, J.-P. Rabès, C. Lamaze, C. Boileau, France, Lebanon 1101 11:55 FAMILIAL HYPERCHOLESTEROLEMIA IS NOT RELATED TO BRAIN WHITE MATTER DAMAGE BUT ACCENTUATES CORTICAL ATROPHY IN AGE-RELATED REGIONS C. Valls-Pedret, D. Vidal-Piñeiro, N. Bargalló, D. Bartrés-Faz, Emilio Ros, Spain 1503 12:10 GENETICS IN FAMILIAL HYPERCHOLESTEROLEMIA AND THE RISK OF CARDIOVASCULAR EVENTS Joost Besseling, B. Sjouke, B. Hutten, J. Kastelein, K. Hovingh, The Netherlands 1595 12:25 NATURAL HISTORY OF AUTOSOMAL DOMINANT HYPERCHOLESTEROLEMIA CAUSED BY GAIN-OF-FUNCTION MUTATIONS IN PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (PCSK9) (FUNDED BY REGENERON/SANOFI) Joep C. Defesche, S.W. Fouchier, B. Sjouke, J. Mendoza, S. Mellis, K. Miller, G.D. Swergold, on behalf of the PCSK9 Natural History Study (NHS) Group, The Netherlands, USA 147 26 Wednesday, June 5, 2013 10:50-12:40 Room René Leriche A METABOLIC REGULATION OF APOLIPROTEIN A-I-CONTAINING LIPOPROTEINS Chairpersons: Arnold von Eckardstein Xavier Collet Time 10:50 CONSTITUTIVE INHIBITION OF PLASMA CHOLESTERYL ESTER TRANSFER PROTEIN (CETP): FUNCTIONALITY AND DYSFUNCTIONALITY IN ANIMAL MODELS AND HUMAN POPULATIONS Laurent Lagrost, France 11:15 ROLE OF THE ENDOTHELIUM IN HDL METABOLISM Arnold von Eckardstein, Switzerland Abstract No 11:40 APOA-I INCREASES INSULIN SECRETION FROM PANCREATIC BETA CELLS VIA A CAMP-PKA-FOXO1 DEPENDANT MECHANISM Blake J. Cochran, R.J. Bisoendial, K.-A. Rye, Australia 1312 11:55 THE ROLE OF HIGH DENSITY LIPOPROTEINS IN HUMAN MACROPHAGE POLARIZATION X.L. Moore, M.K. Lee, Y. Fu, J.Y. Wong, L. Fang, A.M. Dart, D. Sviridov, Jaye Chin-Dusting, Australia, China 403 12:10 HIGH-DENSITY LIPOPROTEINS ASSOCIATED MICRORNAS: ORIGINS AND FUNCTION Fatiha Tabet, K.C. Vickers, L.F. Cuesta Torres, P.J. Barter, A.T. Remaley, K.-A. Rye, Australia, USA 946 12:25 GLYCATION OF APOLIPOPROTEIN C1 LEADS TO A LOSS OF ITS ABILITY TO INHIBIT CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY DURING DIABETES Benjamin Bouillet1,2, T. Gautier, D. Blache, J.-P. Pais de Barros, L. Duvillard, J.-M. Petit1,2, L. Lagrost, B. Verges1,2, France 27 435 Wednesday, June 5, 2013 10:50-12:40 Room René Leriche B ADVENTITIA AND PERIVASCULAR FAT Chairpersons: Patricia Iozzo Steven B. Feinstein Time 10:50 UPDATE ON ARTERIAL VASA VASORUM: DIAGNOSIS MONITORING AND POTENTIAL THERAPIES Steven.B. Feinstein, USA 11:15 PERIVASCULAR AND EPICARDIAL FAT Patricia Iozzo, Italy Abstract No 11:40 AUTOCRINE PRODUCTION OF SONIC HEDGEHOG ENHANCES PDGF BB-MEDIATED MIGRATION AND PERICYTE RECRUITMENT TO NEOVESSELS Q. Yao1,2, M.-A. Renault, C. Chapouly, S. Vanderdionck, I. Belloc, B. Jaspard-Vinassa, C. Desgranges, Alain-Pierre Gadeau, France 1330 11:55 ROLE OF THE TUMOR SUPPRESSOR CDKN2A/P16INK4A IN THE DEVELOPMENT OF PERIVASCULAR ADIPOSE TISSUE K. Wouters, S.A. Hannou, C. Cudejko, J. Vanhoutte, A. Lucas, K. Bantubungi, E. Vallez, E. Bouchaert, A. Tailleux, B. Staels, Réjane Paumelle, France 12:10 12:25 PERIVASCULAR ADIPOSE TISSUE AND CORONARY ATHEROSCLEROSIS Rudolf Poledne, Z. Tonar, D. Kautznerova, I. Malek, J. Pirk, V. Lanska, J. Pitha, Czech Republic 1015 284 MACROPHAGES BULLYING T CELLS IN TYPE-A STANFORD ACUTE AORTIC DISSECTION Livia Ferri, M. Proietta, C. di Gioia, L. Tritapepe, M. Leopizzi, C. Fantozzi, C. Chiappetta, I. Nofroni, C. Della Rocca, E. Marinari, A.P. Mitterhofer, A. Negro, A. Koverech, M. Taurino, F. Del Porto, Italy 699 11:40-12:40 Auditorium Anitschkow ADVANCED CLINICAL SEMINAR: DO NEW BIOMARKERS HAVE ANY ADDED VALUE IN CLINICAL DECISION MAKING? Chairperson: Jan Boren Time 11:40 LIPIDS AND LIPOPROTEINS Borge Nordestgaard, Denmark 12:05 INFLAMMATION AND IMAGING Wolfgang Koenig, Germany 28 POSTER PRESENTATIONS Written by top experts in the field Cardiology Advances in er Editor: J.S. Bor Vol. 47 Therapy in Antiplatelet ib ACS and A-F Editors ny V.L. Serebrua D. Atar (Advances in Cardiology, Vol. 47) TXA2 ADP TRAP Thrombin Editors: TPɲ Ticlopidine Clopidogrel Prasugrel Ticagrelor TXAS Aspirin Antiplatelet Therapy in ACS and A-Fib PGH 2 COX Platelet acƟvaƟon AA ɲ IIbɴ3 Fibrinogen GP IIb/IIIa inhibitors PLA2 Serebruany, V.L. (Towson, Md.); Atar, D. (Oslo) Over the last several decades, a better understanding of the pathogenesis of coronary heart disease and atrial fibrillation has led to refinements in antithrombotic strategies and clinical outcomes. With this in mind, some of the issues outlined in this book are: • New insights in genetic testing • Modification of individualized antiplatelet therapy based on rapid bedside platelet analyzers • Current update of pros and cons of novel antiplatelet agents (such as prasugrel and ticagrelor) • Conventional antiplatelet strategies with aspirin and clopidogrel • Experimental antiplatelet agents like PAR-1 thrombin receptor antagonists or aptamers Get your copy at the Wisepress booth! ki13248 Please visit www.karger.com/adcar and read free chapter excerpts, more details and full table of contents. Monday, June 3, 2013 13:40-14:40 Moderated Poster Area MODERATED POSTER SESSION A Session 1: ENDOTHELIUM AND ATHEROTHROMBOSIS Moderator: Yiannis Chatzizisis, Greece Poster Board No. M1 HOMOCYSTEINE REDUCES PROTEIN S-NITROSYLATION IN ENDOTHELIAL CELLS Y. Chen, Enqi Liu, J. Fan, China, Japan Abstract No 170 M2 CILOSTAZOL ENHANCES CIRCULATING ENDOTHELIAL PROGENITOR CELLS AND COLLATERAL FORMATION MEDIATED BY MODIFYING VASCULO-ANGIOGENIC BIOMARKERS IN PATIENTS WITH PERIPHERAL ARTERIAL DISEASE I-Chih Chen, T.-H. Chao , S.-Y. Tseng, Y.-S. Tsai, Y.-Y. Huang, P.-Y. Liu, H.-Y. Ou, Y.-H. Li, G.-Y. Shi, H.-L. Wu, J.-H. Chen, Taiwan R.O.C. 214 M3 TAMOXIFEN ELICITS ATHEROPROTECTION THROUGH ESTROGEN RECEPTOR ALPHA AF-1 BUT DOES NOT ACCELERATE REENDOTHELIALIZATION Coralie Fontaine, A. Abot, A. Billon-Gales, G. Flouriot, E. Grunenwald, A. Vinel, M.-C. Valéra, P. Gourdy, J.-F. Arnal, France 356 DELETION OF FHL2 GENE IMPAIRED ISCHEMIA-INDUCED BLOOD FLOW RECOVERY Pao-Hsien Chu, P.-H. Huang, S.-J. Lin, Taiwan R.O.C. 459 M4 M5 OXIDIZED-HDL3 MODULATES THE EXPRESSION OF T-PA IN HUMAN ENDOTHELIAL CELLS Feng Tao Liu, Z.Y. Yu, Z. Ren, Z.H. Tang, R. Wang, L.S. Liu, Z. Wang, Z.S. Jiang, China 725 M6 ENDOTHELIAL CELL-SPECIFIC ROLE OF THE CHEMOKINE RECEPTOR CXCR4 IN WIRE INJURY-INDUCED ATHEROSCLEROSIS Baixue Zhou, Germany 1155 M7 RED BLOOD CELL INFILTRATION OF ATHEROMATOUS LESIONS INDUCE A VICIOUS CYCLE LEADING TO ENDOTHELIAL ACTIVATION AND CYTOTOXICITY Viktória Jeney1,2, L. Potor, M. Soares, G. Balla1,2, J. Balla, Hungary, Portugal 1323 M8 REMODELING AND ENDOTHELIAL SHEAR STRESS EXHIBIT SIGNIFICANT LONGITUDINAL VARIATION IN HUMAN CORONARY ARTERIES: IMPACT ON PLAQUE PROGRESSION Antonios P. Antoniadis, M.I. Papafaklis, S. Takahashi, M. Tsuda, S. Mizuno, Y. Makita, T. Domei, T. Ikemoto, A.U. Coskun, J. Honye, S. Nakamura, S. Saito, C.L. Feldman, P.H. Stone, USA, Japan 29 1526 Monday, June 3, 2013 13:40-14:40 Moderated Poster Area MODERATED POSTER SESSION A (contd.) Session 2: REGULATION OF CELLULAR LIPID METABOLISM IN ATHEROGENESIS Moderator: Bart Staels, France Poster Board No. Abstract No M59 ADIPOCYTE ENHANCER-BINDING PROTEIN 1 OVER-EXPRESSION PROMOTES AND ABLATION ATTENUATES ATHEROSCLEROSIS IN APOE-/- AND LDLR-/- MICE Amin Majdalawieh, O. Bogachev, X. Pan, L. Zhang, H.-S. Ro, United Arab Emirates, Canada 315 M60 AUTOPHAGY IS NOT INVOLVED TO PROVIDE FREE CHOLESTEROL FOR ABCA1-MEDIATED EFFLUX IN CHOLESTEROL-LOADED HUMAN MONOCYTE-DERIVED MACROPHAGES 512 Natalie Fournier1,2, M. Passet, E. Girard, B. Vedie, J.-L. Paul1,2, France M61 CHOLESTEROL EFFLUX IS ASSOCIATED WITH PLASMA TRIACYLGLYCEROL SPECIES CONTAINING SATURATED FATTY ACIDS Peter J. Meikle, T.W. Ng, R. Tan, K. Huynh, G. Wong, C.K. Barlow, J.M. Weir, A.J. White, B.A. Kingwell, Australia 640 M62 ACUTE EFFECT OF PLANT STANOL ESTERS ON HEPATIC STEROL METABOLISM IN MICE Els De Smet, R. Mensink, M. Konings, G. Brufau, B. Groen, R. Havinga, M. Schonewille, A. Kerksiek, D. Lütjohann, J. Plat, The Netherlands, Germany 801 M63 GENETIC DETERMINATION OF PLASMA CHOLESTEROL EFFLUX CAPACITY IS GENDER-SPECIFIC AND INDEPENDENT OF HDLCHOLESTEROL LEVELS Elise Florence Villard, P. El Khoury, E. Frisdal, E. Bruckert, K. Clement, D. Bonnefont-Rousselot, R. Bittar, W. Le Goff, M. Guerin, France 973 M64 GLOBAL NRF2 DEFICIENCY ALLEVIATES DIET-INDUCED ATHEROSCLEROSIS IN LDL RECEPTOR DEFICIENT MICE Anna-Kaisa Ruotsalainen, E. Tapper, J. Lappalainen, S. Ylä-Herttuala, A.L. Levonen, Finland 984 M65 PHYTOSTEROL FEEDING DOWNREGULATES MOUSE PERITONEAL MACROPHAGE ABCG1 MRNA AND PREVENTS ATHEROSCLEROSIS IN LDL-RKO MICE Renata Bombo, R. Machado, M. Afonso, M.S. Lavrador, E. Nakandakare, V. Nunes, C. Lin, M. Koike, E. Quintao, A.M. Lottenberg, Brazil 1053 M66 CHOLESTEROL CRYSTALS IN EARLY HUMAN ATHEROMA B. Ho-Tin-Noé, V. Ollivier, J.-B. Michel, Sophie Vo, France 30 1461 Monday, June 3, 2013 13:40-14:40 Moderated Poster Area MODERATED POSTER SESSION A (contd.) Session 3: ROLE OF LIPASES IN LIPID AND LIPOPROTEIN METABOLISM Moderator: Geesje Dallinga-Thie, Netherlands Poster Board No. M67 Abstract No THE EFFECTS OF VEGF-A ON ATHEROSCLEROSIS, LIPOPROTEIN PROFILE AND LIPOPROTEIN LIPASE IN HYPERLIPIDEMIC MOUSE MODELS Annukka Kivelä, S. Heinonen, M. Dijkstra, E. Gurzeler, J. Huusko, P. Mäkinen, P. Leppänen, V. Olkkonen, U. Eriksson, M. Jauhiainen, S. YläHerttuala, Finland, Sweden 229 M68 AAV-DRIVEN OVEREXPRESSION OF HANGPTL4 IN APOE-/- MICE AGGRAVATES PLASMA TG LEVELS BUT DOES NOT AFFECT POSTHEPARIN PLASMA LIPOPROTEIN LIPASE ACTIVITY Madelene Eriksson, S.K. Nilsson, C. Schlein, J. Heeren, Sweden, Germany517 M69 RELATIONSHIP OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 MASS AND ACTIVITY WITH TRADITIONAL LIPOPROTEIN BIOMARKERS IN A TUNISIAN STUDY Mazen Belhabib, M. Caslake, A. Bekir, H. Chahed, J. Cooney, A. Lewis, D. Bedford, T. Trimech, F. Maatouk, S. Ferchichi, A. Miled, Tunisia, UK 518 M70 LIPOPROTEIN LIPASE MASS IS A PREDICTIVE MARKER OF CARDIOVASCULAR AND CEREBROVASCULAR EVENT IN FUTURE Haruki Imamura, K. Endo, A. Saiki, T. Murano, Y. Sato, T. Yamaguchi, N. Ban, H. Kawana, D. Nagayama, A. Nagumo, M. Ohira, S. Yamamura, K. Shirai, I. Tatsuno, Japan M71 A NEW POSSIBLE ROLE FOR ANGIOPOIETIN LIKE 3, A REGULATOR OF TRIGLYCERIDE METABOLISM, IN MODULATING INSULIN RESISTANCE Marianna Maranghi, I. Minicocci, G. Tiseo, A. Montali, P. Coletta, D. Pergolini, G. Pigna, E. Ciociola, C. Durante, G. Labbadia, M. Arca, Italy 1017 M72 APOA5 DOWN-REGULATION THROUGH MIRNA INTERACTION WITH POLYMORPHIC 3'UTR Cyrielle Caussy1,2, S. Charrière1,2, C. Marçais2,3, M. Di Filippo2,4, A. 1090 Sassolas2,4, E. Lefai, S. Rome, P. Moulin1,2, France M73 HUMAN POLYMORPHISMS OF ENDOTHELIAL LIPASE DISPLAY IMPAIRED HYDROLYSIS OF HIGH-DENSITY LIPOPROTEINS Kate Shearston, D. Marais, K.-A. Rye, G. Lambert, Australia, South Africa, France 1316 M74 ANGPTL4 MEDIATES THE SHORT-POSTER BOARD NO. EFFECTS OF TNF-ALPHA ON THE LPL SYSTEM IN 3T3-L1 ADIPOCYTES Evelina Vorrsjö, E. Makoveichuk, T. Olivecrona, G. Olivecrona, Sweden 1378 31 652 Monday, June 3, 2013 13:40-14:40 Moderated Poster Area MODERATED POSTER SESSION A (contd.) Session 4: EVALUATION AND TREATMENT OF CARDIOVASCULAR RISK FACTORS IN THE YOUNG AND THE ELDERLY Moderator: George D. Davey-Smith, UK Poster Board No. Abstract No M117 ENDOGENOUS SEX HORMONES, ISCHEMIC HEART DISEASE AND EARLY DEATH IN WOMEN FROM THE GENERAL POPULATION Marianne Benn, S.S. Voss, G.B. Jensen, B.G. Nordestgaard, Denmark 977 M118 HIGH PREVALENCE OF ATHEROSCLEROSIS IN ARTERIES OF ANCIENT MUMMIES DETERMINED BY NEAR INFRARED SPECTROSCOPY Mohammad Madjid, N. Fuenffinger, K. Stutler, R. Lodder, USA 328 M119 LIPOPROTEIN(A): FASTING AND NONFASTING LEVELS, INFLAMMATION, AND CARDIOVASCULAR RISK PREDICTION Anne Langsted, P.R. Kamstrup, B.G. Nordestgaard, Denmark 1175 M120 INCREASE IN THE INCIDENCE OF ACUTE CORONARY SYNDROME AFTER THE 2011 EAST JAPAN NATURAL DISASTER: CONCORDANCE WITH SEQUENTIAL QUAKE SHOCKS Masanobu Niiyama, F. Tanaka, K. Sato, T. Takahashi, T. Onoda, T. Segawa, M. Onodera, M. Kawakami, M. Ogawa, H. Endoh, T. Matsumoto, K. Sakata, M. Nakamura, Japan 1413 M121 FIBROBLAST GROWTH FACTOR 23, PARATHYROID HORMONE AND RISK OF HEART FAILURE IN A MIDDLE-AGED GERMAN POPULATION Romina di Giuseppe, B. Buijsse, F. Hirche, J. Wirth, M. Arregui, H.W. Hense, J. Dierke, H. Boeing, G.I. Stangl, C. Weikert, Germany, Norway 1475 M122 LABORATORY VS. NON-LABORATORY YOUTH RISK MEASURES FOR PREDICTING CAROTID INTIMA-MEDIA THICKNESS IN ADULTHOOD: THE INTERNATIONAL CHILDHOOD CARDIOVASCULAR COHORT CONSORTIUM Costan G. Magnussen1,2, M. Juonala, J.S.A. Viikari, G.S. Berenson, T. Dwyer, A. Venn, O.T. Raitakari, Finland, Australia, USA 1477 M123 USE OF FIBRATES IN PRIMARY PREVENTION IN TYPE 2 DIABETIC PATIENTS AT HIGH CARDIOVASCULAR RISK Ronan Roussel1,2, C. Chaignot, A. Weill, B. Hansel, F. Travert, P. Ricordeau, F. Alla, H. Allemand, France 1514 M124 NAFLD IS INCREASED IN PATIENTS WITH CV RISK FACTORS AND IS CORRELATED WITH ATHEROSCLEROSIS AND THE FRAMINGHAM SCORE R. Pais, D. Rosenbaum, P. Lebray, D. Thabut, M. Rudler, V. Ratziu, Philippe Giral, France 1242 M125 EFFECT OF SHIFTWORK ON BODY MASS INDEX AMONG FEMALE NURSES IN KOREA: NURSES' HEALTH STUDY Min-Ju Kim, H.-Y. Park, K.-H. Son, M.-C. Cho, D.-J. Choi, the Nurses Health Study(NHS) Group, Republic of Korea 1435 32 Monday, June 3, 2013 13:40-14:40 Moderated Poster Area MODERATED POSTER SESSION A (contd.) Session5: INFLAMMATION AND HDL Moderator: Dimitris Kardassis, Greece Poster Board No. Abstract No M75 EVIDENCE FROM AN INTEGRATED ANALYSIS COMBINING GENOMICS, TRANSCRIPTOMICS, AND LIPIDOMICS HIGHLIGHTS THE ROLE OF INFLAMMATION IN LOW HDL-C STATE Pirkka-Pekka Laurila, I. Surakka, A.-P. Sarin, J. Tang, T. Hyötyläinen, S. Söderlund, J. Naukkarinen, J. Kettunen, D. Mirel, J. Soronen, T. Lehtimäki, A. Ruokonen, C. Ehnholm, J. Eriksson, V. Salomaa, A. Jula, O. Raitakari, M.R. Järvelin, A. Palotie, M. Oresic, S. Ripatti, M. Jauhiainen, M.-R. Taskinen, Finland, USA 429 M76 HUMAN APOA-I AFFECTS THE INFLAMMATORY RESPONSE MEDIATED BY CD4+ T-LYMPHOCYTES DURING ATHEROSCLEROSIS PROGRESSION Marco Busnelli, F. Sala, L. Arnaboldi, C. Parolini, S. Manzini, D. Norata, G. Chiesa, Italy 1497 M77 GENETIC ABLATON OF THE P2Y2 NUCLEOTIDE RECEPTOR REDUCES VASCULAR INFLAMMATION AND ATHEROSCLEROSIS IN MICE Cheikh Seye, S. Qian, USA 1360 M78 PREVALENCE OF CLASSICAL CD14++/CD16- BUT NOT OF INTERMEDIATE CD14++/CD16+ MONOCYTES IN HYPOALPHALIPOPROTEINEMIA Fabrizia Bonacina, L. Cutuli, F. Sala, L. Grigore, S. Fiorelli, K. Garlaschelli, 1533 G. Chiesa, A.L. Catapano1,3, G.D. Norata1,2, Italy M79 RESVERATROL ADMINISTRATION OR SIRT1 OVEREXPRESSION DOES NOT INCREASE LXR SIGNALING AND MACROPHAGE-TO-FECES REVERSE CHOLESTEROL TRANSPORT IN VIVO J.C. Escolà-Gil, J. Julve, G. Llaverias, M. Urpi-Sarda, R. Silvennoinen, M. Lee-Rueckert, C. Andres-Lacueva, Francisco Blanco-Vaca, Spain, Finland1288 M80 OXLIG-1, A NOVEL PPAR GAMMA AGONIST, INCREASE ABCA1 EXPRESSION AND PROMOTE CHOLESTEROL EFFLUX FROM THP-1 MACROPHAGES Yan Chi, R. Wang, F. Zhang, X. Han, Z. Liu, Q. Liu, China 1379 M81 ASSOCIATION BETWEEN REVERSE CHOLESTEROL TRANSPORT RATE AND LIPOPROTEIN BIOMARKERS USING A NOVEL IN SILICO MODEL OF LIPOPROTEIN METABOLISM AND KINETICS James Lu, K. Hϋbner, E.A. Brinton, M.N. Nanjee, N.A. Mazer, Switzerland, Germany, USA 1108 33 Monday, June 3, 2013 13:40-14:40 Moderated Poster Area MODERATED POSTER SESSION A (contd.) Session 6: THROMBOSIS AND HEMOSTASIS: RELATION TO ATHEROTHROMBOSIS AND LIPOPROTEINS Moderator: Pierre Morange, France Poster Board No. Abstract No M9 HIGH CONCENTRATIONS OF LOW DENSITY LIPOPROTEINS (LDL) INCREASE TISSUE FACTOR-DEPENDENT PROCOAGULANT ACTIVITY IN PLATELETS Susana Contreras-Duarte, C. González, P. Hidalgo, A. Rigotti, D. Mezzano, O. Panes, Chile 227 M10 ANTAGONIZING THE EP3 RECEPTOR FOR PGE2 WITH DG-041 PREVENTED THROMBOSIS WITH NO IMPACT ON HEMOSTASIS P. Tilly, A.-L. Charles, S. Ludwig, J.-B. Michel, B. Geny, Jean-Etienne Fabre, France 682 M11 IS PLATELET MEDIATED LEUKOCYTE RECRUITMENT A DRUGABLE TARGET IN ATHEROSCLEROSIS? Matthew James Harrison, G. Nash, S. Watson, E. Rainger, UK 988 M12 M13 M14 OXIDIZED HDL INHIBIT HUMAN PLATELET AGGREGATION Catherine Calzada, E. Véricel, Q.-H. Le, M. Lagarde, P. Moulin, France HDL-BASED THERAPY REDUCES THE HEMORRHAGIC COMPLICATIONS ASSOCIATED WITH TISSUE PLASMINOGEN ACTIVATOR TREATMENT IN EXPERIMENTAL STROKE Bertrand Lapergue, B.Q. Dang, J.P. Desilles, G. Ortiz, S. Delbosc, S. Loyau, L. Louedec, P.O. Couraud, M. Mazighi, J.B. Michel, O. Meilhac, P. Amarenco, France PENTRAXIN 3 DEFICIENCY IS ASSOCIATED WITH INCREASED ARTERIAL THROMBOSIS IN ANIMAL MODELS Fabrizia Bonacina, S.S. Barbieri, L. Cutuli, P. Amadio, M. Sironi, B. Bottazzi, C. Garlanda, E. Tremoli1,2, A. Mantovani, G.D. Norata1,4, A.L. Catapano1,5, Italy 34 1041 301 1553 Monday, June 3, 2013 13:40-14:40 Moderated Poster Area MODERATED POSTER SESSION A (contd.) Session 7: FATTY ACIDS INFLUENCE ATHEROSCLEROSIS AND ITS RISK FACTORS: THE DOUBLE BONDS DECIDE Moderator: Michel Lagarde, France Poster Board No. Abstract No M126 IMPACT OF N-3 TO N-6 POLYUNSATURATED FATTYACID RATIO ON VASCULAR FUNCTION IN ISCHEMIC HEART DISEASE PATIENTS WITH IDEAL LDL LEVEL Hitoshi Adachi, H. Takamatsu, J. Tomono, S. Oshima, Japan 241 M127 MEDITERRANEAN DIET AND 2.4-YEAR CHANGES IN ULTRASOUNDASSESSED CAROTID INTIMA-MEDIA THICKNESS AND PLAQUE: A SUB-STUDY OF THE PREDIMED TRIAL Aleix Sala-Vila, E.S. Romero-Mamani, R. Gilabert, I. Núñez, E. Toledo, V. Ruiz-Gutiérrez, R.M. Lamuela-Raventós, X. Pintó, F. Arós, M. Fiol, M.I. Covas, M.Á. Martínez-González, R. Estruch, E. Ros, Spain 981 M128 OMEGA 3 FATTY ACIDS PROMOTE MACROPHAGE REVERSE CHOLESTEROL TRANSPORT IN HAMSTER FED HIGH FAT DIET Fatima Kasbi Chadli1,2, E.-H. Nazih, M. Krempf, P. Nguyen, K. Ouguerram, France 421 M129 VASCULAR FUNCTION AFTER N-3 POLYUNSATURATED FATTY ACIDS SUPPLEMENTATION IN AN ANIMAL MODEL OF EXPERIMENTAL MENOPAUSE Andrea Grillo, P. Losurdo, E. Panizon, M. Jevnikar, L. Macaluso, M. Zanetti, B. Fabris, R. Carretta, Italy 450 M130 IMPACT OF DIFFERENT DIETARY TREATMENTS ON THE MOLECULAR LIPID PROFILE OF AORTIC PLAQUES DEVELOPED IN APOE-/- MICE C. Parolini, M. Busnelli, Stefano Manzini, G. Ganzetti, M. Jänis, K. Tarasov, R. Hurme, K. Ekroos, R. Laaksonen, G. Chiesa, Italy, Finland 1509 Session 8: INSULIN-RESISTANT STATES: MODULATORS OF LIPID METABOLISM AND CARDIOVASCULAR DISEASE Moderator: Klaus Parhofer, Germany M131 M132 INFLUENCE OF LIPIDS AND APOLIPOPROTEINS ON INSULIN SENSITIVITY: A CROSS-SECTIONAL ANALYSIS OF THE RISC STUDY Simona Baldi, F. Bonnet, M. Laville, C. Morgantini, E. Ferrannini, A. Natali, on behalf of the RISC Investigators, Italy, France 419 HETEROZYGOUS GLUCOKINASE KNOCKOUT MICE IN APOE DEFICIENT BACKGROUND REPRESENT A NOVEL DISEASE MODEL FOR TYPE 2 DIABETES AND ATHEROSCLEROSIS Suvi E. Heinonen, A.-C. Andréasson, M. Brusberg, L. Hägerstrand, K. Jennbacken, A. Ahnmark, B. Leighton, A.-C. Jönsson-Rylander, Sweden, UK632 35 Monday, June 3, 2013 13:40-14:40 Moderated Poster Area MODERATED POSTER SESSION A (contd.) Session 8: INSULIN-RESISTANT STATES: MODULATORS OF LIPID METABOLISM AND CARDIOVASCULAR DISEASE (contd.) Poster Board No. Abstract No M133 ASSOCIATION OF FASTING GLUCOSE LEVEL 6 MONTHS AFTER PCI WITH THE DEVELOPMENT OF MACE IN DES-IMPLANTED PATIENTS ON STATIN THERAPY Dong Oh Kang, H.S. Seo, B. Choi, C. Choi, E.M. Lee, S.I. Lim, S.W. Kim, J.O. Na, C.U. Choi, H.E. Lim, J.W. Kim, E.J. Kim, S.-W. Rha, C.G. Park, D.J. Oh, Republic of Korea 661 M134 PCSK9 CIRCULATING LEVELS ARE INCREASED IN TYPE 2 DIABETIC PATIENTS REGARDLESS OF METABOLOMIC DIFFERENCES IN LIPID PROFILE Anna Cabré, N. Plana, D. Ibarretxe, M. Heras, S. Guaita, J. Merino, J. Ribalta, L. Masana, Spain 979 M135 LIPID PROFILES IN DIABETIC SUBJECTS - ASSOCIATIONS WITH CARDIOVASCULAR DISEASE O. Piksasova, V. Schnecke, F. Agakov, P. McKeigue, K. Leander, U. deFaire, I. Brady, H. Looker, H. Colhoun, A. Hamsten, John Öhrvik, SUMMIT Consortium, Sweden, UK 1057 CHARACTERIZATION OF ATHEROGENIC DYSLIPIDEMIA USING A NOVEL NMR-BASED ADVANCED LIPOPROTEIN TEST IN TYPE 2 DIABETIC SUBJECTS Roger Mallol1,2,3, A. Cabré1,2,3, M.A. Rodríguez1,2,3, N. Amigó1,2,3, M. Vinaixa1,2,3, N. Plana, M. Heras1,2,3, L. Masana1,2,3, X. Correig1,2,3, Spain 1502 M136 M137 PREVALENCE AND DETERMINANTS OF FATTY LIVER IN NORMAL WEIGHT AND OVERWEIGHT YOUNG ADULTS. THE CARDIOVASCULAR RISK IN YOUNG FINNS STUDY Mervi Oikonen, M. Kähönen, J. Viikari, M. Juonala, O.T. Raitakari1,4, The Young Finns Study Group, Finland 1537 M138 VANCOMYCIN DECREASES INSULIN SENSITIVITY AND IS ASSOCIATED WITH ALTERATIONS IN INTESTINAL MICROBIOTA AND BILE ACID COMPOSITION IN METABOLIC SYNDROME SUBJECTS Ruud Kootte, C. Out, S. Fuentes, L. Jonker, A. Vrieze, E. Van Nood, F. Holleman, G. Dallinga-Thie, H. Romijn, M. Soeters, E. Blaak, D. Reijnders, M. Ackermans, M. Serlie, F. Knop8,9, J. Holst, E. Stroes, E. Zoetendal, W. De Vos3,10, J. Hoekstra, B. Groen, M. Nieuwdorp1,4, The Netherlands, Denmark M139 ISCHEMIC HEART DISEASE IN OVERWEIGHT AND OBESITY WITH AND WITHOUT THE METABOLIC SYNDROME M. Thomsen, Børge Nordestgaard, Denmark 1472 36 1546 Tuesday, June 4, 2013 12:40-13:40 Moderated Poster Area MODERATED POSTER SESSION B Session 9: CELL DYSFUNCTIONS IN ATHEROGENESIS Moderator: Catherine Shanahan, UK Poster Board No. Abstract No M15 AUTOPHAGY AND ER STRESS ARE INDUCED BY OXIDIZED LDL: ROLE IN VASCULAR ENDOTHELIAL CELLS APOPTOSIS AND ATHEROGENESIS C. Muller, M. Bisserier, A. Swiader, A. Nègre-Salvayre, F. Lezoualc'h, R. Salvayre, Cécile Vindis, France 478 M16 SPHINGOSINE-1-PHOSPHATE (S1P) INHIBITS TNFA-STIMULATED MMP-9 EXPRESSION IN MACROPHAGES AND SMOOTH MUSCLE CELLS VIA DIFFERENT S1P RECEPTORS Petra Keul, G. Heusch, B. Levkau, Germany 619 M17 IN VIVO IMAGING OF APOPTOSIS AT ATHEROSCLEROTIC PLAQUE USING APOPTOSIS-TARGETED PEPTIDE PROBE Byung-Heon Lee, Republic of Korea 731 M18 SP1, ACETYLATED HISTONE-3 AND P300 REGULATE TRAIL TO PROMOTE PDGF-BB-MEDIATED VASCULAR SMOOTH MUSCLE CELL PROLIFERATION AND MIGRATION 936 N.S. Azahri, B. Di Bartolo, L. Khachigian, Mary Kavurma1,2, Australia M19 DISSECTION OF ACTIVATION FUNCTIONS (AF-1 AND AF-2) OF ESTROGEN RECEPTOR ALPHA IN VIVO: UNCOUPLING VASCULAR AND SEXUAL EFFECTS Anne Abot, C. Fontaine, I. Raymond-Letron, G. Flouriot, M. Adlanmerini, M. Buscato, P. Gourdy, F. Lenfant, J.-F. Arnal, France 1021 M20 EFFECT OF PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 (PCSK9) ON SMOOTH MUSCLE CELL PROLIFERATION AND MIGRATION Nicola Ferri, G. Tibolla, F. Maglione, P. Costet, A. Corsini, A.L. Catapano1,3, Italy, France 1209 M21 MACROPHAGE PHENOTYPIC DIVERSITY DURING ATHEROSCLEROSIS REGRESSION J.E. Feig, Y. Vengrenyuk, B. Hewing1,2, K.J. Moore, Edward A. Fisher, USA, Germany 1424 MICRORNAS 143/145 DEFICIENCY LIMITS ATHEROSCLEROSIS IN ANIMAL MODELS Federica Sala, L. Elia, G. Condorelli1,2, A.L. Catapano1,3, G.D. Norata1,4, Italy 1468 M22 37 Tuesday, June 4, 2013 12:40-13:40 Moderated Poster Area MODERATED POSTER SESSION B (contd.) Session 10: ANGIOGENESIS Moderator: Jan Nilsson, Sweden Poster Board No. Abstract No M23 NOGO B EXPRESSION AND THE ADVENTITIAL LYMPHANGIOGENESIS IN HUMAN DONOR'S ARTERIES Katarzyna Magdalena Drożdż, I. Grzegorek, M. Chmielewska, A. Gomułkiewicz, K. Jabłońska, A. Piotrowska, D. Janczak, M. PodhorskaOkołów, P. Dzięgiel, A. Szuba, Poland 152 M24 ANTI-ATHEROSCLEROTIC EFFECT OF AN ANTIBODY THAT BINDS TO EXTRACELLULAR MATRIX GLYCOSAMINOGLYCANS Ana María Vázquez, Y. Soto, E. Acosta, L. Delgado, A. Pérez, V. Falcón, M.A. Becquer, A. Fraga, V. Brito, I. Alvarez, T. Griñán, Y. FernándezMarrero, A. López-Requena, M. Noa, E. Fernández, Cuba 238 M25 QA-1-RESTRICTED CD8+ T REGULATORY CELLS CONTROL THE DEVELOPMENT OF PRO-ATHEROGENIC ADVENTITIAL TERTIARY LYMPHOID ORGANS IN APOLIPOPROTEIN E KO MICE Marc Clement1,2, K. Guedj1,2, M. Morvan, J. Khallou-Laschet1,2, A.-T. Gaston, 386 H.-J. Kim3,4, H. Cantor3,4, G. Caligiuri, A. Nicoletti1,2, France, USA M26 ELASTASE INHIBITOR TREATMENT PREVENTS ABDOMINAL AORTIC ANEURYSM GROWTH Sandrine Delbosc1,2, J.-M. Alsac1,3, M. Rouer, L. Louedec1,2, M. Philippe1,2, 610 O. Meilhac1,2, C. Whatling, J.B. Michel1,2, France, Sweden M27 NON-INVASIVE ASSESSMENT OF NEOANGIOGENESIS AND INFLAMMATION IN INTERMEDIATE LESIONS OF HUMAN CAROTID ARTERIES Maria Drakopoulou, K. Toutouzas, G. Benetos, C. Aggeli, C. Nikolaou, I. Felekos, H. Grassos, A. Synetos, K. Stathogiannis, A. Karanasos, E. Tsiamis, E. Siores, C. Stefanadis, Greece, UK M28 M29 M30 837 -/- TRAIL MICE DISPLAY REDUCED NEOVASCULARISATION AFTER HIND-LIMB ISCHEMIA: IMPLICATIONS FOR TRAIL IN REGULATING PROANGIOGENIC GENES Belinda Ann Di Bartolo, L.P. Lourenco, N.S. Azahri1,2, L.M. Khachigian, M.M. Kavurma2,3, Australia 924 SIRT1 SUPPRESSES HYPOXIA-INDUCED HIF-1Α EXPRESSION AND ATTENUATES NEOINTIMA FORMATION VIA INHIBITION OF NEOVASCULARIZATION AFTER ARTERIAL INJURY IN MICE Jinung Bae, S.J. Lee, K.W. Hong, S.Y. Park, C.D. Kim, Republic of Korea 933 ESSENTIAL ROLE FOR SPHINGOSINE-1-PHOSPHATE IN OXIDIZED LOW DENSITY LIPOPROTEIN-INDUCED ANGIOGENESIS. PREVENTION BY ANTI-S1P ANTIBODY Caroline Camaré, M. Trayssac, B. Garmy-Susini, R. Sabbadini, R. Salvayre, A. Nègre-Salvayre, France, USA 1257 38 Tuesday, June 4, 2013 12:40-13:40 Moderated Poster Area MODERATED POSTER SESSION B (contd.) Session 11: LIFESTYLE Moderator: Angela Rivellese, Italy Poster Board No. Abstract No M140 GENETIC VARIATION IN FADS MODIFIES THE ASSOCIATION BETWEEN ALA/LA AND INCIDENCE OF CARDIOVASCULAR DISEASE Sophie Hellstrand, E. Sonestedt, U. Ericson, B. Gullberg, E. Wirfält, M. Orho-Melander, Sweden 411 M141 TRANS-FATTY ACID ACCELERATES THROMBUS FORMATION IN VIVO THROUGH INHIBITING ENDOTHELIAL ANTI-THROMBOGENIC ACTIONS Kensuke Kondo, T. Yasuda, J. Yamamoto, T. Monguchi, K. Mori, M. Hasokawa, H. Haraguchi, H. Nakajima, M. Shinohara, R. Toh, T. Ishida, K. Hirata, Japan 414 M142 CARBOHYDRATE-RICH FOODS AND RISK OF CARDIOVASCULAR DISEASE IN THE MALMÖ DIET AND CANCER COHORT Emily Sonestedt, S. Hellstrand, M. Orho-Melander, Sweden M143 THE EFFECTS OF DARK CHOCOLATE ON ENDOTHELIAL FUNCTION AND PULSE-WAVE SHAPE IN HEALTHY PERSONS Oxana Dikur, A. Parfenov, Y. Ashikhmin, Russia 810 M144 THE DECREASE IN CARDIORESPIRATORY FITNESS IS RELATED TO THE RISK OF ACUTE MYOCARDIAL INFARCTION AND ALL-CAUSE MORTALITY IN MEN Jari Laukkanen, S. Kurl, R. Rauramaa, KIHD, Finland 853 M145 REPLACING A SFA DIET WITH DIETARY PUFA REDUCES HEPATIC PCSK9 MRNA AND PLASMA LIPIDS IN RATS Sara Straniero, L. Persson, B. Angelin, M. Rudling, Sweden 597 1225 M146 EFFECTS OF OMEGA-3 POLYUNSATURATED FATTY ACIDS ON ADIPOKINE LEVELS IN PATIENTS UNDERGOING PERCUTANEOUS CORONARY INTERVENTION Grzegorz Gajos, M. Mostowik, J. Zalewski, J. Nessler, A. Undas, Poland 1235 M147 EFFECTS OF LIFESTYLE MODIFICATION PROGRAM IN REDUCTION OF RISK FACTORS IN PATIENTS WITH CORONARY HEART DISEASE Solmaz Aminpour, M. Shahamfar, J. Shahamfar, Iran 704 M148 THE FREQUENCY OF ALCOHOL CONSUMPTION IS ASSOCIATED WITH THE INCREASED RISK OF STROKE MORTALITY Sanna Helena Rantakömi, S. Kurl, J. Sivenius, J. Kauhanen, J.A. Laukkanen, Finland 1345 39 Tuesday, June 4, 2013 12:40-13:40 Moderated Poster Area MODERATED POSTER SESSION B (contd.) Session 12: CV RISK FACTORS 1 Moderator: Jacques Bonnet, France Poster Board No. Abstract No M149 ASSOCIATIONS BETWEEN SERUM URIC ACID AND MARKERS OF SUBCLINICAL ATHEROSCLEROSIS. THE CARDIOVASCULAR RISK IN YOUNG FINNS STUDY Mervi Oikonen, M. Wendelin-Saarenhovi, L.-P. Lyytikäinen3,4, O.T. Raitakari, Cardiovascular Risk in Young Finns Study, Finland 444 M150 OUTCOMES FOLLOWING CORONARY REVASCULARIZATION IN CHINESE, SOUTH ASIAN AND WHITE PATIENTS WITH ACUTE MYOCARDIAL INFARCTION D. Gasevic1,2, N. Khan, H. Qian, S. Karim, G. Simkus, H. Quan, M. Mackay, Amir Ayyobi, Canada 514 M151 SKIN CANCER AS A MARKER OF SUN EXPOSURE AND RISK OF MYOCARDIAL INFARCTION, HIP FRACTURE, AND EARLY DEATH Peter Brøndum-Jacobsen, B.G. Nordestgaard, S.F. Nielsen, M. Benn, Denmark 573 M152 MAXIMAL BLOOD PRESSURE RESPONSE TO EXERCISE IS ASSOCIATED WITH SUBCLINICAL ATHEROSCLEROSIS IN NORMOTENSIVE ADOLESCENTS Egle Silva, J.J. Villasmil, L. Chacin, G. Bermudez, M. Bracho, A. Gonzalez, Venezuela 638 M153 HIGH LEVEL OF TRIGLYCERIDES IN CHILDREN OF PATIENTS WITH EARLY CORONARY ARTERY DISEASE: RELATION TO OWN AND PARENTAL RISK FACTORS Mikhail Konnov, L. Dobordzhginidze, N. Gratsiansky, Russia 919 M154 PROGNOSTIC ROLE OF EOSINOPHILIC CATIONIC PROTEIN IN PATIENTS WITH ST-ELEVATION MYOCARDIAL INFARCTION TREATED BY PRIMARY PERCUTANEOUS CORONARY INTERVENTION A. Imaeva, F. Fracassi, N. Cosentino, L. Cataneo, M. Roberto, D. Schiavino, G. Niccoli, F. Crea, Giorgia Copponi, Russia, Italy 1183 M155 FACTOR V LEIDEN AND PROTHROMBIN G20210A MUTATION IN ISCHEMIC STROKE PATHOGENESIS: ESH STROKE SURVEY Alena Krajcoviechova, P. Wohlfahrt, O. Mayer, J. Vanek, J. Kvasnicka, T. Kvasnicka, J. Filipovsky, R. Cifkova, Czech Republic 1473 M156 METABOLOMIC PROFILES IN LEAN AND OBESE ADOLESCENTS Yun Chen, M. Peitzsch, G. Eisenhofer, P. Friberg, Sweden, Germany M157 1483 THE RELATION OF ALCOHOL CONSUMPTION LEVELS WITH THE CARDIO-ANKLE VASCULAR INDEX (CAVI) IS J-SHAPED IN HEALTHY MIDDLE-AGED JAPANESE MEN Masatsune Ogura, T. Kobayashi, K. Ikewaki, Japan 494 40 Tuesday, June 4, 2013 12:40-13:40 Moderated Poster Area MODERATED POSTER SESSION B (contd.) Poster Board No. Abstract No Session 13: ATHEROSCLEROSIS-REGULATING FACTORS IN MOUSE AND MAN 2 Moderator: Christoph Binder, Austria M31 LACK OF NICOTINE ALPHA 7 RECEPTOR ACCELERATES ATHEROSCLEROSIS IN LDLR-/- MICE Maria E. Johansson1,2, M.A. Ulleryd, A.M. Lundberg, L. Fogelstrand, Z.-Q. Yan, G.K. Hansson, Sweden 591 M32 LOW DOSE ASPIRIN REDUCES PLASMA CHEMERIN LEVELS IN CORONARY ARTERY DISEASE PATIENTS THROUGH REDUCTION OF ADIPOSE TISSUE INFLAMMATION Magdalena Herová1,2, C. Loretz, M. Schmid, M. Hersberger1,2, Switzerland 1027 M33 CROSS-TALK BETWEEN ACTIVATED MONOCYTES AND SMOOTH MUSCLE CELLS UP-REGULATES RESISTIN EXPRESSION BY ACTIVATION OF STAT3 TRANSCRIPTION FACTOR A.M. Gan, M. Pirvulescu, D. Stan, V. Simion, M. Calin, I. Manduteanu, Elena Butoi, Romania 1326 M34 THE EXTRACELLULAR TOLL LIKE RECEPTOR 4 REGULATOR RP105 (CD180) AMELIORATES ATHEROSCLEROSIS VIA ITS ROLE ON BCELLS J.C. Karper, S.C.A. de Jager, M.M. Ewing, M.R. De Vries, I. Bot, R. Arens, J.W. Jukema, Z. Mallat, C.J. Binder6,7, J. Kuiper, Paul H.A. Quax, The Netherlands, France, Austria 987 M35 THERAPEUTIC TARGETING OF JAK/STAT/SOCS PATHWAY REDUCES ATHEROSCLEROSIS IN DIABETIC MICE Carlota Recio, A. Oguiza, I. Lazaro, B. Mallavia, J. Egido, C. GomezGuerrero, Spain 509 M36 TWEAK/FN14 INTERACTION PROMOTES OXIDATIVE STRESS THROUGH NADPH OXIDASE ACTIVITY IN MACROPHAGES J. Madrigal-Matute1,2, Valvanera Fernández-Laso, C. Sastre, J. Egido, J.L. Martín-Ventura, G. Zalba, L.M. Blanco-Colio, Spain, USA 268 M37 MOLECULAR MECHANISMS INVOLVED IN RESISTIN DEPENDENT ENHANCED MONOCYTES INFILTRATION IN THE VESSEL WALL Monica Madalina Pirvulescu, A.M. Gan, E. Butoi, D. Stan, V. Simion, M. Calin, I. Manduteanu, Romania 1400 M38 CANNABINOIDS INCREASE ENDOGENOUS HYDROGEN SULFIDE (H2S) SIGNALING IN PERIVASCULAR ADIPOSE TISSUE BY IMPAIRING MITOCHONDRIAL BIOGENESIS Jerzy Bełtowski, A. Jamroz-Wiśniewska, Poland 1511 41 Tuesday, June 4, 2013 12:40-13:40 Moderated Poster Area MODERATED POSTER SESSION B (contd.) Session 14: MULTIPLE ROLES OF HDL AND ITS TRANSPORTERS IN ATHEROSCLEROSIS AND RELATED DISEASES Moderator: Arie van Tol, Netherlands Poster Board No. M82 M83 Abstract No HDL IMPROVES GLUCOSE HOMEOSTASIS AND REDUCES ATHEROSCLEROSIS IN TRAIL-/-APOE-/- MICE Belinda Di Bartolo, S.P. Cartland, K.-A. Rye, M.M. Kavurma1,3, Australia LOWER ADRENAL STEROID PRODUCTION IN MICE AND HUMANS WITH LOW HDL-CHOLESTEROL DUE TO MUTATIONS IN LCAT Andrea Bochem, A. Holleboom, J.A. Kuivenhoven, M. van Eck, G.K. Hovingh, E. Stroes, M. Hoekstra, The Netherlands 941 1305 M84 HIGH-DENSITY LIPOPROTEINS INHIBIT CHEMOKINE EXPRESSION AND PROLIFERATION OF VASCULAR SMOOTH MUSCLE CELLS Christina Bursill, E. van der Vorst, L. Vanags, L. Dunn, H. Prosser, K.-A. Rye, Australia, The Netherlands 1315 M85 APOLIPOPROTEIN A- I INHIBITS LPS-INDUCED ATHEROSCLEROSIS IN APOE-/- MICE K. Yin, Chao-Ke Tang, China 1329 M86 WHAT HAPPENS TO HDL PARTICLE FUNCTIONALITY FOLLOWING ACUTE MYOCARDIAL INFARCTION? Fabiana Hanna Rached1,2, L. Camont, M. Lhomme, M. Miname, R.D. Santos, C.V. Serrano Jr, M.J. Chapman, A. Kontush, Brazil, France 1415 EFFECTS OF THE CETP INHIBITOR DS-1442 ON REVERSE CHOLESTEROL TRANSPORT AND ATHEROSCLEROSIS Naoki Terasaka, Japan 1277 M87 M88 PARAOXONASE 1 (PON1) REGULATES THE CHOLESTEROL EFFLUX VIA THE PPARΓ-LXRΑ-ABCA1 PATHWAY Souade Ikhlef, H. Berrougui, P. Camponova, S. Loued, A. Khalil, Canada 1250 M89 THE CELL SURFACE-RESIDENT ATP-BINDING CASSETTE TRANSPORTER A1 (ABCA1) IS UBIQUITINATED AND SORTED TO LYSOSOME FOR DEGRADATION Tadahaya Mizuno, H. Hayashi, S. Naoi, Y. Sugiyama, H. Kusuhara, Japan 1399 42 Tuesday, June 4, 2013 12:40-13:40 Moderated Poster Area M ODERATED POSTER SESSION B (contd.) Session 15: NOVEL INSIGHTS INTO THE ROLE OF MICRONUTRIENTS IN CARDIOVASCULAR RISK AND DISEASE Moderator: Eric Bruckert, France Poster Board No. Abstract No M158 VITAMIN D SUPPLEMENTATION REDUCES RESTENOSIS FOLLOWING CORONARY INTERVENTION IN HYPERCHOLESTEROLEMIC SWINE Devendra K. Agrawal, G.K. Gupta, M.G. Delcore, W.J. Hunter, USA 843 M159 CONSUMPTION OF PLANT STEROL-ENRICHED FOODS MODESTLY INCREASES PLASMA/SERUM PLANT STEROL CONCENTRATIONS - A META-ANALYSIS Rouyanne T. Ras, H. Hiemstra, Y. Lin, M. Vermeer, G.S.M.J.E. Duchateau, E.A. Trautwein, The Netherlands 1022 M160 EFFECTS OF DIETARY POLYPHENOLS AND/OR N-3 FATTY ACIDS ON OXIDATIVE STRESS IN PEOPLE AT HIGH CARDIOVASCULAR RISK: THE ETHERPATHS PROJECT Giuseppina Costabile, G. Annuzzi, L. Bozzetto, G. Della Corte, A. Giacco, M. Vitale, E. Griffo, S. Cocozza, G. Della Pepa, L. Di Marino, F. Pasanisi, G. Riccardi, A.A. Rivellese, Italy 1495 M161 IS TAKING HEALTH FUNCTIONAL FOOD BENEFICIAL FOR CARDIOVASCULAR SYMPTOMS? Mi-Seung Shin, B.R. Kim, I.-M. Chung, D.-J. Choi, Republic of Korea 1559 M162 PHYTOSTEROL SUPPLEMENTATION AFFECTS STEROL PLASMA LEVELS IN PATIENTS UNDER LIPID-LOWERING THERAPIES Livia Nascimento Matos, D.M. Tegani, F.A. Fonseca, S.A. Barbosa, S.H. Kasmas, R.M. Povoa, M.C. Izar, Brazil 145 M163 FLAVANOL METABOLITES REDUCE MONOCYTE ADHESION AND MODULATE GENE EXPRESSION INVOLVED IN ATHEROSCLEROSIS DEVELOPMENT THROUGH MAPK-P38 OR NFKB-P65 SIGNALING PATHWAYS S. Claude, Dragan Milenkovic, C. Boby, C. Morand, France 438 M164 DIETS RICH IN POLYPHENOLS AND/OR N-3 FATTY ACIDS REDUCE FASTING AND POSTPRANDIAL TRIGLYCERIDE- RICH LIPOPROTEINS: THE ETHERPATHS PROJECT Lutgarda Bozzetto, G. Annuzzi, R. Giacco, P. Cipriano, A. Mangione, G. Costabile, G. Anniballi, C. Vetrani, F. Conte, A. Rivieccio, L. Patti, G. Riccardi, A.A. Rivellese, Italy 1576 43 Tuesday, June 4, 2013 12:40-13:40 Moderated Poster Area MODERATED POSTER SESSION B (contd.) Session 16: TREATMENT OF DYSLIPIDEMIA: FROM GUIDELINES TO GOALS AND MECHANISMS Moderator: Anders G. Olsson, Sweden Poster Board No. Abstract No M90 BRIDGED NUCLEIC ACID (BNA)-BASED ANTISENSE THERAPEUTICS TARGETING PCSK9 Mariko Harada-Shiba, T. Yamamoto1,2, H. Yasuhara1,2, S. Wada1,2, F. 331 Wada1,2, M.-A. Shibata, S. Obika, Japan M91 CHANGES IN BIOMARKER LEVELS WITH ROSUVASTATIN OR SIMVASTATIN IN COMBINATION WITH EZETIMIBE: RESULTS FROM GRAVITY Christie M. Ballantyne1,2, R. Hoogeveen1,2, V.A. Cain, M.K. Palmer, B.W. Karlson5,6, on behalf of the GRAVITY Study Investigators, USA, UK, Sweden1054 M92 EFFECTS OF 12 WEEKS OF TREATMENT WITH RN316 (PF-04950615), A HUMANIZED MONOCLONAL ANTIBODY BINDING PCSK9, IN HYPERCHOLESTEROLEMIC SUBJECTS ON STATINS B. Gumbiner, T. Joh, C. Udata, P. Forgues, C. Baum, Pamela D Garzone, USA 1271 M93 MIPOMERSEN, AN APOLIPOPROTEIN B SYNTHESIS INHIBITOR, REDUCES LDL-C IN HoFH PEDIATRIC PATIENTS Frederick J. Raal, S. Selvey, South Africa, USA 1368 M94 INHIBITION OF PCSK9 WITH AMG 145, A MONOCLONAL ANTIBODY, REDUCES LP(A): INSIGHTS FROM THE POOLED PROFICIO STUDY Evan A. Stein, R.P. Giugliano, M.S. Sabatine, M.J. Koren, G. Langslet, H. Bays, D. Blom, M. Eriksson, R. Dent, S.M. Wasserman, F. Huang, T. Liu, M. Albizem, R. Scott, F. Raal, USA, Norway, South Africa, Sweden 1621 M95 RAMIPRIL INCREASES WALKING ABILITY IN PERIPHERAL ARTERY DISEASE PATIENTS WITH CLAUDICATION; POTENTIAL ROLE OF INFLAMMATION, ADHESION, COAGULATION AND ANGIOGENESIS A.A. Ahimastos, A.K. Natoli, C. Latouche, M. Reddy-Luthmoodoo, J. Golledge, Bronwyn A. Kingwell, Australia M96 M97 THE IMPACT OF LOW DENSITY LIPOPROTEIN RECEPTOR (LDLR) GENE MUTATION ON THE RESPONSE TO THERAPY IN PATIENTS WITH FAMILIAL HYPERCHOLESTEROLEMIA Vasiliki Metaxa, C. Pitsavos, I. Skoumas, E. Oikonomou, A. Miliou, C. Masoura, L. Papadimitriou, C. Stefanadis, Greece 719 1135 GUIDELINES EAS/ESC AND VERY HIGH RISK TYPE 2 DIABETIC PATIENTS IN A FRENCH REGISTRY: HOW FARE TO LDL-C GOAL? Michel Krempf, B. Cariou, M. Le Bras, N. Fuertes, E. Nobecourt, France 1608 44 Tuesday, June 4, 2013 12:40-13:40 Moderated Poster Area MODERATED POSTER SESSION B (contd.) Session 16: TREATMENT OF DYSLIPIDEMIA: FROM GUIDELINES TO GOALS AND MECHANISMS (contd.) Moderator: Anders G. Olsson, Sweden Poster Board No. Abstract No M98 EFFECTS OF STATINS ON LIPID PROFILE IN CHRONIC KIDNEY DISEASE PATIENTS: A META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS D. Nikolic, S. Nikfar, P. Salari, M. Rizzo, K.K. Ray, M.J. Pencina, D.P. Mikhailidis, P.P. Toth, S.J. Nicholls, J. Rysz, M. Abdollahi, Maciej Banach, Lipid and Blood Pressure Meta-Analysis Collaboration Group, Italy, Iran, USA, UK 1414 M99 EFFECTS OF HIGH-DOSE ATORVASTATIN MONOTHERAPY ON CIRCULATING PCSK9 LEVELS IN HETEROZYGOUS FAMILIAL HYPERCHOLESEROLEMIA Kouji Kajinami, E. Ueno, K. Tanabe, N. Fujioka, H. Akao, T. Tsuchiya, Y. Kawai, M. Kitayama, Japan 247 Session 17: IMAGING OF THE ARTERIAL WALL AS A DIAGNOSTIC AND PROGNOSTIC INDICATOR OF ATHEROSCLEROTIC DISEASE Moderator: Lale Tokgozoglu, Turkey M165 DIFFERENCES IN CULPRIT RUPTURED PLAQUE MORPHOLOGY IN STEMI AND NSTEMI BY OPTICAL COHERENCE TOMOGRAPHY Konstantinos Toutouzas, A. Karanasos, E. Tsiamis, M. Riga, M. Drakopoulou, A. Synetos, A. Papanikolaou, K. Stathogiannis, D. Tousoulis, C. Stefanadis, Greece 557 M166 THE EFFECT OF AGING ON ATHEROSCLEROTIC PLAQUE INFLAMMATION AND MOLECULAR CALCIFICATION: A PET CT IMAGING STUDY Björn Alexander Blomberg, A. Thomassen, J.A. Simonsen, M. Hildebrandt, A.C.P. Diederichsen, H. Mickley, A. Alavi, P.F. Høilund-Carlsen, Denmark, USA 1107 M167 CONTRAST-ENHANCED ULTRASOUND: EARLY DIAGNOSIS METHOD FOR CAROTID ATHEROSCLEROSIS 1131 Adelina Baleanu-Curaj1,2, Germany 45 Tuesday, June 4, 2013 12:40-13:40 Moderated Poster Area MODERATED POSTER SESSION B (contd.) Session 17: IMAGING OF THE ARTERIAL WALL AS A DIAGNOSTIC AND PROGNOSTIC INDICATOR OF ATHEROSCLEROTIC DISEASE (contd.) Moderator: Lale Tokgozoglu, Turkey Poster Board No. Abstract No M168 CLINICAL AND ECHOCARDIOGRAPHIC FACTORS RELATED TO FALSE RESULTS OF EXERCISE TOLERANCE TEST Hakimeh Sadeghian, E. Hakki Kazazi, A. Zoroufian, M. Sahebjam, A. Jalali, M. Pashang, Iran 116 M169 18 F-FLUOROMETHYLCHOLINE PET IMAGING OF INFLAMED ATHEROSCLEROTIC PLAQUES IN MICE Sanna Hellberg, A. Roivainen1,2, J. Silvola, H. Liljenbäck1,2, P. Saukko, J. Knuuti, A. Saraste1,4, Finland 993 M170 PROGNOSTIC VALUE OF CORONARY CALCIFICATION USING 64SLICE CORONARY CT ANGIOGRAPHY FOR PREDICTING CORONARY DISEASE EXTENT AND CARDIAC EVENTS Y.-C. Liu, Zhonghua Sun, T. Chan, P.-K. Tsay, I.-C. Hsieh, C.-C. Chen, M.S. Wen, Y.-L. Wan, Taiwan R.O.C., Australia, Canada 310 M171 MULTILEVEL ASSESSMENT OF ATHEROSCLEROTIC BURDEN USING 64-SLICE MULTI-DETECTOR CT IN ACUTE STROKE PATIENTS: COCASE STUDY, PART TWO Laura Mechtouff, L. Boussel, S. Cakmak, J.-L. Lamboley, A.-M. Schott, T.H. Cho, L. Derex, N. Nighoghossian, P.-C. Douek, France 422 46 Tuesday, June 4, 2013 13:40-14:40 Moderated Poster Area MODERATED POSTER SESSION C Session 18: IMMUNITY AND ATHEROSCLEROSIS Moderator: Menno De Winther, Netherlands Poster Board No. Abstract No M39 THE BALANCE OF T-REGULATORY AND T-HELPER 1 AND 17 LYMPHOCYTE SUBSETS IN BLOOD OF PATIENTS WITH CORONARY ATHEROSCLEROSIS Alexandra Potekhina, E. Pylaeva, K. Raskina, A. Kuranova, S. Provatorov, E. Noeva, T. Arefieva, Russia 958 M40 ROLE OF HIF1Α IN IMMUNE REGULATION OF ATHEROSCLEROSIS Sweena M. Chaudhari, J.C. Sluimer, M. Koch, H.D. Manthey, M. Busch, H.M. Hermanns, A. Zernecke1,3, Germany, The Netherlands 1454 M41 ROLE OF PSGL-1 EXPRESSING CD4 T CELLS IN ACUTE CORONARY SYNDROME Kayoko Sato, K. Kitamura, K. Gomita, N. Hagiwara, Japan 1310 M42 INDUCTION OF DENDRITIC-CELL MEDIATED T-CELL ACTIVATION BY MODIFIED BUT NOT NATIVE LDL: HEAT SHOCK PROTEINS AS POSSIBLE T-CELL ANTIGENS A. Liu, J. Ming, Y. He, R. Fiskesund, A. Frostegård, E. Ninio, S.-A. Karabina, Johan Frostegård, Sweden, France 1505 M43 IMMUNOSENESCENCE CHARACTERIZED BY A RESTRICTED T CELL RECEPTOR REPERTOIRE IN ACUTE CORONARY SYNDROMES Roland Klingenberg, C. Brokopp, A. Grives, A. Courtier, N. Pasqual, E. Vlaskou, L.A. Altwegg, O. Gämperli, C.A. Wyss, S. Hoerstrup, W. Maier, R. Corti, U. Landmesser, T.F. Lüscher, C.M. Matter, Switzerland, France 961 M44 T-CELL CO-STIMULATION BY CD28-CD80/86 AND ITS NEGATIVE REGULATOR CTLA-4 STRONGLY INFLUENCE ACCELERATED ATHEROSCLEROSIS DEVELOPMENT M.M. Ewing, R.C.M. de Jong, J.C. Karper, M.R. De Vries, R. Arens, J.W. Jukema, J. Kuiper, Paul H.A. Quax, The Netherlands 1020 Session 19: METABOLIC REGULATION OF APOLIPROTEIN A-I-CONTAINING LIPOPROTEINS Moderator: Laurent Lagrost, France M100 AUTOANTIBODIES TO APOLIPOPROTEIN A-1 AND MYLEOPEROXIDASE AS PREDICTORS OF MAJOR ADVERSE CARDIOVASCULAR EVENTS AFTER CAROTID ENDARTERECTOMY Nicolas Vuilleumier, F. Montecucco, G. Spinella, S. Pagano, M. Bertolotto, B. Pane, A. Pende, P. Roux-Lombard, C. Combescure, F. Dallegri, F. Mach, D. Palombo, Switzerland, Italy 55 47 Tuesday, June 4, 2013 13:40-14:40 Moderated Poster Area MODERATED POSTER SESSION C (contd.) Session 19: METABOLIC REGULATION OF APOLIPROTEIN A-I-CONTAINING LIPOPROTEINS Moderator: Laurent Lagrost, France Poster Board No. Abstract No M101 HDLS PREVENT HEMORRHAGE INDUCED BY NEUTROPHIL ELASTASE Lourdes Maria Varela Perez, C. Hoteit, J.-B. Michel1,2,3, B. Ho-Tin-Noé1,2, O. 589 Meilhac1,2,4, France M102 ADDITION OF S1P TO RECONSTITUTED HDL ENHANCE POSTISCHEMIC PROTECTION IN VIVO M. Frias, V. Braunersreuther, F. Montecucco, S. Lecour, F. Mach, Richard William James, Switzerland, South Africa 475 M103 INTRAPERITONEAL ADMINISTRATION OF 2S, APOA-I MIMETIC PEPTIDE, INHIBITS THE ATHEROSCLEROTIC LESION DEVELOPMENT IN HIGH FAT HIGH CHOLESTEROL-FED APOE-/- MICE B.-S. Lee, S.H. Han, Y. Kim, J. Yu, Jeong Euy Park, Republic of Korea 960 M104 ARE EXTREMELY AND MODERATELY INCREASED LEVELS OF HDL CHOLESTEROL PROTECTIVE AGAINST ALL-CAUSE MORTALITY IN THE JAPANESE GENERAL POPULATION? Tomonori Okamura, Y. Murakami, H. Iso, A. Tamakoshi, M. Yamada, K. Miura, H. Ueshima, for the EPOCH-JAPAN Research Group, Japan 213 M105 OXIDATIVE STRESS AND IMPAIRED HIGH-DENSITY LIPOPROTEIN ANTI-OXIDANT CAPACITY IN HUMAN ABDOMINAL AORTIC ANEURYSM Sandrine Delbosc1,2, T. Dejouvencel1,2, D. Diallo1,2, L. Louedec1,2, P. Rossignol3,4, G. Leseche1,5, J.B. Michel1,2, O. Meilhac1,2, France 673 M106 THE ROLE OF APOA-I VS HDL-C AS A DETERMINANT OF CAROTID INTIMA-MEDIA-THICKNESS Sanni Söderlund, M. Jauhiainen, C. Ehnholm, M.-R. Taskinen, Finland 1258 Session 20: CARDIOVASCULAR DISEASE AND ITS PREVENTION IN PATIENTS WITH CHRONIC INFLAMMATORY AND CHRONIC RENAL DISEASE Moderator: Naveed Sattar, UK M172 M173 USEFULNESS OF NEW STAGING SYSTEM FOR PREDICTING CARDIOVASCULAR RISK AND ALL-CAUSE DEATH IN CHRONIC KIDNEY DISEASE: A VALIDATION STUDY Yorihiko Koeda, T. Segawa, F. Tanaka, M. Ohsawa, K. Tanno, K. Sakata, M. Nakamura, Iwate KENCO, Japan ACCELERATED ADIPOSE TISSUE DYSFUNCTION AND CARDIOVASCULAR RISK IN INDIVIDUALS OF SOUTH ASIAN ETHNICITY Shirya Rashid, P. Power, M. Melone, Canada 48 28 198 Tuesday, June 4, 2013 13:40-14:40 Moderated Poster Area MODERATED POSTER SESSION C (contd.) Session 20: CARDIOVASCULAR DISEASE AND ITS PREVENTION IN PATIENTS WITH CHRONIC INFLAMMATORY AND CHRONIC RENAL DISEASE (contd.) Moderator: Naveed Sattar, UK Poster Board No. Abstract No M174 ANACETRAPIB DOSE-DEPENDENTLY DECREASES ATHEROSCLEROSIS DEVELOPMENT AND ADDS TO THE BENEFICIAL EFFECTS OF ATORVASTATIN IN APOE*3LEIDEN.CETP MICE S. Kühnast1,2, Sam J.L. van der Tuin3,4, L.M. Havekes1,2,3, P.C.N. Rensen, K. Willems van Dijk3,4, J.W.A. Van der Hoorn1,2, J.W. Jukema, H.M.G. Princen, The Netherlands 382 M175 HIGH-DENSITY LIPOPROTEIN CHOLESTEROL EFFLUX CAPACITY PREDICTS GRAFT FAILURE BUT NOT CARDIOVASCULAR AND ALLCAUSE MORTALITY IN RENAL TRANSPLANT RECIPIENTS Wijtske Annema, A. Dikkers, J.F. de Boer, R.P.F. Dullaart, J.-S.F. Sanders, S.J.L. Bakker, U.J.F. Tietge, The Netherlands 484 M176 DIFFERENT ASSOCIATIONS BETWEEN VISCERAL AND SUBCUTANEOUS ADIPOSITY AND CORONARY ARTERY CALCIFICATION Sophie Eastwood, T. Tillin, J. Heasman, A. Wright, P. McKeigue, A. Hughes, N. Chaturvedi, UK 1099 M177 THE EFFECT OF MAXIMUM BODY WEIGHT IN LIFEPOSTER BOARD NO. ON THE DEVELOPMENT OF CORONARY ARTERY DISEASE IN TYPE 2 DIABETES: MAXWEL-CAD STUDY Soo Lim, J.-W. Suh, S.M. Kang, M.K. Moon, H.C. Jang, S.H. Choi, Republic of Korea 1171 M178 ESTROGENS CONTROL THE STROMA-VASCULAR FRACTION OF ADIPOSE TISSUE AND PREVENT HIGH-FAT DIET-INDUCED INFLAMMATION Elodie Riant, S. Handgraaf, A. Fabre, M. Guillaume, A. Zakaroff, D. Teixeira, 1373 A. Bouloumié, R. Burcelin, J.-F. Arnal, P. Gourdy1,3, France, Portugal M179 DYSFUNCTIONAL HIGH-DENSITY LIPOPROTEIN AS A NOVEL CARDIOVASCULAR RISK FACTOR AFTER KIDNEY TRANSPLANTATION Chantal Kopecky, M. Haidinger, C. Kaltenecker, M. Antlanger, G. Marsche, M. Holzer, J. Kovarik, J. Werzowa, M. Hecking, M.D. Säemann, Austria 1383 M180 EFFECTS OF STATINS ON CARDIOVASCULAR ENDPOINTS IN CHRONIC KIDNEY DISEASE PATIENTS: A META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS D. Nikolic, S. Nikfar2,3, P. Salari, D.P. Mikhailidis, M. Rizzo1,6, P.P. Toth, J. Rysz, M. Abdollahi, Maciej Banach, Italy, Iran, UK, USA, Poland 1409 49 Tuesday, June 4, 2013 13:40-14:40 Moderated Poster Area MODERATED POSTER SESSION C (contd.) Session 20: CARDIOVASCULAR DISEASE AND ITS PREVENTION IN PATIENTS WITH CHRONIC INFLAMMATORY AND CHRONIC RENAL DISEASE (contd.) Moderator: Naveed Sattar, UK Poster Board No. M181 Abstract No RENAL OUTCOMES OF USE OF STATINS IN CHRONIC KIDNEY DISEASE PATIENTS: A META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS Maciej Banach, D. Nikolic, S. Nikfar, P. Salari, D.P. Mikhailidis, M. Rizzo, P.P. Toth, M. Abdollahi, J. Rysz, Poland, Italy, Iran, UK, USA 1410 Session 21: PRIMARY DYSLIPIDEMIA Moderator: Sebastiano Calandra, Italy M107 HIGH FREQUENCY AND MILD PHENOTYPE IN TRUE HOMOZYGOUS OR DOUBLE HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA CAUSED BY PCSK9 MUTATION (E32K) IN JAPAN Hiroshi Mabuchi, A. Nohara, T. Noguchi, J. Kobayashi, M.-A. Kawashiri, H. Tada, M. Mori, T. Inoue, C. Nakanishi, M. Yamagishi, A. Inazu, Hokuriku FH Research Group, Japan 307 M108 ELEVATED MONOCYTE-DERIVED MICROPARTICLES IN PATIENTS WITH FAMILIAL HYPERCHOLESTEROLEMIA: A POTENTIAL ATHEROSCLEROSIS RISK MARKER Morten Hjuler Nielsen, H. Irvine, S. Vedel, B. Raungaard, H. Beck-Nielsen, A. Handberg, Denmark 457 M109 AFTER LDLR, APOB AND PCSK9, APOE IS ANOTHER MAJOR GENE OF AUTOSOMAL DOMINANT HYPERCHOLESTEROLEMIA Mathilde Varret1,2, M. Marduel, K. Ouguerram, V. Serre2,4, D. BonnefontRousselot, K.E. Berge, M. Devillers, G. Luc, J.-M. Lecerf, L. Tosolini, M. Abifadel1,9, T.P. Leren, J.-P. Rabès1,10,11, C. Boileau1,10,11, The French Research Network on ADH, France, Norway, Lebanon 562 M110 FAMILIAL HYPERCHOLESTEROLEMIA AND EXOME SEQUENCING: IDENTIFICATION OF THE FIRST COMPOUND HETEROZYGOTE FOR APOB AND PCSK9 MUTATIONS Marianne Abifadel1,2, G. Peloso3,4, J.-P. Rabès1,5,6, J.P. Pirruccello3,4,7, M. Varret, V. Carreau, N. Stitziel3,4, L. Tosolini, Y. Ghaleb, N. Gupta, S. Gabriel, A. Carrié, E. Bruckert8,9, S. Kathiresan3,4, C. Boileau1,5,6, France, Lebanon, USA 636 M111 CIRCULATING PCSK9 IS A STRONG DETERMINANT OF PLASMA TRIGLYCERIDES, BUT NOT OF LDL CHOLESTEROL IN FAMILIAL DYSBETALIPOPROTEINEMIA Martijn Brouwers, M. van Greevenbroek, R. Konrad, J. Troutt, N. Schaper, C. Stehouwer, The Netherlands, USA 845 50 Tuesday, June 4, 2013 13:40-14:40 Moderated Poster Area MODERATED POSTER SESSION C (contd.) Session 21: PRIMARY DYSLIPIDEMIA (contd.) Moderator: Sebastiano Calandra, Italy Poster Board No. Abstract No M112 PREVALENCE AND CLINICAL CHARACTERISTICT OF PATIENTS WITH HOMOZYGOUS AUTOSOMAL DOMINANT HYPERCHOLESTEROLEMIA IN THE NETHERLANDS Barbara Sjouke, D.M. Kusters, I. Kindt, J. Besseling, J. Defesche, E.J. Sijbrands, J.E. Roeters van Lennep, A. Stalenhoef, S.W. Fouchier, J.J.P. Kastelein, G.K. Hovingh, The Netherlands 865 M113 PCSK9 IN HETEROZYGOUS FH (HEFH) PATIENTS Mathias Chatelais, F. Petrides, D. Marais, G. Lambert2,4, France, Australia, South Africa 903 M114 FAMILIAL COMBINED HYPERLIPIDEMIA: IDENTIFICATION OF LDLR MUTATIONS IN A POPULATION FROM SOUTHERN ITALY Maria Nicoletta D'Agostino1,2, M.D. Di Taranto, A. D'Angelo, A. Ruotolo, C. 1093 Giacobbe, G. Marotta, M. Gentile, P. Rubba, G. Fortunato1,2, Italy M115 IDENTIFICATION OF NOVEL ANGPTL3 MUTATIONS ASSOCIATED WITH SEVERE HYPOBETALIPOPROTEINEMIA Patrizia Tarugi, R. Spina, E. Pinotti, A.B. Cefalù, D. Noto, E. Di Leo, I. Crisci, R. Miccoli, M. Averna, Italy M116 LDL-CHOLESTEROL ASSOCIATED GWAS SNPS INTERFERE WITH THE CLINICAL PHENOTYPE OF FAMILIAL HYPERCHOLESTEROLEMIA Sigrid W. Fouchier, G.M. Dallinga-Thie, J.C. Defesche, J.J.P. Kastelein, S. Kathiresan, G.K. Hovingh, The Netherlands, USA 1493 1263 Session 22: INFLAMMATION AND INFECTION IN EXPERIMENTAL AND CLINICAL ATHEROSCLEROSIS Moderator: Giuseppina Caligiuri, Italy M45 NLRP3 INFLAMMASOME ACTIVATION IN MONOCYTES OF PATIENTS WITH ACUTE CORONARY SYNDROME Kai Yin1,2, J.-F. Li, D. Xie, J.-Y. Peng, J.-J. Zhang, G. Wang, Q.-J. Gui2,3, Y.L. Tu, Z.-S. Jiang, C.-K. Tang, China 97 M46 MICRORNA-1264 UPREGULATES SUPPRESSOR OF CYTOKINE SIGNALING 3 EXPRESSION UNDER INFLAMMATORY CONDITIONS IN HUMAN CORONARY ARTERY SMOOTH MUSCLE CELLS Devendra K. Agrawal, K. Dhar, D. Pankajakshan, USA 836 M47 CORRELATION BETWEEN ACTIVATION OF T LYMPHOCYTES AND HERPES VIRUSES IN ATHEROSCLEROTIC PLAQUES Jean-Charles Grivel, O. Ivanova, N. Pinegina, A. Lebedeva, E. Nikitskaya, A. Shpektor, L. Margolis, E. Vasilieva, USA, Russia 974 51 Tuesday, June 4, 2013 13:40-14:40 Moderated Poster Area MODERATED POSTER SESSION C (contd.) Session 22: INFLAMMATION AND INFECTION IN EXPERIMENTAL AND CLINICAL ATHEROSCLEROSIS (contd.) Moderator: Giuseppina Caligiuri, Italy Poster Board No. Abstract No M48 HIV INFECTION AND LONG TERM PROGNOSIS OF ACUTE CORONARY SYNDROME. FINAL RESULTS FROM THE PACS-HIV STUDY Franck Boccara1,2,3, M. Mary-Krause, E. Teiger, S. Lang, P. Lim, K. Wahbi, P.G. Steg, C. Funck-Brentano, M. Slama, D. Costagliola, A. Cohen, France 1239 M49 MYXOMAVIRUS-DERIVED SERPIN REDUCES VASCULAR INFLAMMATION AND PROLONGS SURVIVAL IN UNRELATED LETHAL HEMORRHAGIC MOUSE VIRAL SEPSIS H. Chen, D. Zheng, J. Davids, Alexandra Lucas, USA 1423 M50 ELASTIN-DERIVED PEPTIDES POTENTIATE ATHEROSCLEROSIS THROUGH IMMUNE PI3KΓ Stephanie Gayral, R. Garnotel, A. Castaing-Berthou, S. Blaise, E. Berge, N. Malet, P. Maurice, L. Martiny, L. Martinez, L. Duca, M. Laffargue, France 1241 M51 THE PRESENCE OF EXTRA DOMAIN A IN FIBRONECTIN INFLUENCES THE ACUTE INFLAMMATORY RESPONSE Vivek Krishna Pulakazhi Venu, P. Uboldi, A. Muro, A.L. Catapano1,3, G.D. 1299 Norata1,4, Italy M52 CROSSROAD BETWEEN INFLAMMATION, IRON AND LIPIDS IN ATHEROGENESIS Liliana Marques1,2,3, L. Robert, A. Auriac, F. Canonne-Hergaux, L. Costa1,2, Portugal, France 1333 M53 PHOSPHOINOSITIDE 3-KINASE GAMMA DRIVES CD4+ T CELLS INDUCED INTIMAL HYPERPLASIA N. Smirnova, S. Gayral, C. Pedros, N. Malet, A.P. Gadeau, M. Wymann, E. Hirsch, A. Sahoudi, L. Martinez, Muriel Laffargue, France, Switzerland, Italy1567 Session 23: REGULATION OF ISCHEMIA REPERFUSION INJURY Moderator: Jean-Francois Arnal, France M54 M55 THIOREDOXIN AND THIOREDOXIN REDUCTASE CONTROL TISSUE FACTOR ACTIVITY BY THIOL-REDOX-DEPENDENT MECHANISM P. Wang, Y. Wu, X. Li, X. Ma, Liangwei Zhong, China 1419 DAILY ISCHEMIC PRECONDITIONING PROVIDES SUSTAINED PROTECTION FROM ISCHEMIA AND REPERFUSION: A HUMAN STUDY Mary Clare Luca, K. McLaughlin, A. Liuni, J.D. Parker, Canada 778 52 Tuesday, June 4, 2013 13:40-14:40 Moderated Poster Area MODERATED POSTER SESSION C (contd.) Session 23: REGULATION OF ISCHEMIA REPERFUSION INJURY (contd.) Moderator: Jean-Francois Arnal, France Poster Board No. Abstract No M56 HIGH ESTROGEN LEVELS DURING THE LATE FOLLICULAR PHASE OF THE MENSTRUAL CYCLE PROVIDE PROTECTION FROM ISCHEMIA AND REPERFUSION INJURY Mary Clare Luca, A. Liuni, S. Mak, T. Gori, H. Paula, J. Parker, Canada, Germany 914 M57 RELATION BETWEEN LOCAL AND SYSTEMIC LEVELS OF OXIDATIVE STRESS AND NO-REFLOW IN MYOCARDIAL INFARCTION Karim Stamboul, J. Lorin, A. Kahli, M. Zeller, L. Rochette, Y. Cottin1,2, L. 1375 Lorgis1,2, C. Vergely, France M58 INCREASED OEDEMA AND DECREASED CARDIAC FUNCTION IN RIP2DEFICIENT MICE AFTER MYOCARDIAL ISCHEMIA Annika Lundqvist, M. Scharin Täng, M. Lindbom, B. Redfors, K. Skålén, M. Heyden, J. Borén, M. Levin, Sweden 1442 Session 24: EXERCISE AND CARDIOVASCULAR HEALTH: BOTH QUANTITY AND QUALITY COUNT Moderator: Matti Jauhiainen, Finland M182 ASSESSMENT OF PHYSICAL SELF-EFFICACY IS PREDICTIVE FOR CARDIOVASCULAR EVENTS DURING 13-YEARS OF FOLLOW-UP IN INITIALLY HEALTHY 58-YEAR-OLD MEN Caroline Schmidt, G. Bergström, Sweden 202 M183 EXERCISE TRAINING REDUCES VISCERAL FAT INFLAMMATION IN OBESE WOMAN: F-18 FDG TOF (POSTER BOARD NO. OF FLIGHT) PET/CT STUDY Sungeun Kim, H.S. Seo, E.J. Kim, J.H. Na, J.H. Park;, C.U. Choi, H.E. Lim, J.W. Kim, S.-W. Rha, C.-G. Park, D.J. Oh, Republic of Korea 413 M184 ENDURANCE EXERCISE LOWERS AORTAL PLAQUE FORMATION IN YOUNG APOE-/- MICE AND LEADS TO AN INCREASE IN TREGS Bojana Jakic, M. Carlsson, C. Grundtman, G. Wick, Austria 888 M185 MODULATING EFFECT OF CARDIAC REHABILITATION ON AUTONOMIC NERVOUS SYSTEM FUNCTION IN CORONARY ARTERY DISEASE PATIENTS T. Pereira-da-Silva, Marta Nogueira, A. Abreu, P. Rio, N. Santos, T. Alves, S. Silva, R. Cruz Ferreira, Portugal 895 53 Tuesday, June 4, 2013 13:40-14:40 Moderated Poster Area MODERATED POSTER SESSION C (contd.) Session 24: EXERCISE AND CARDIOVASCULAR HEALTH: BOTH QUANTITY AND QUALITY COUNT (contd.) Moderator: Matti Jauhiainen, Finland Poster Board No. M186 M187 Abstract No AEROBIC EXERCISE TRAINING IS THE BEST TREATMENT TO INCREASE THE HIGH-DENSITY LIPOPROTEIN CHOLESTEROL IN PATIENTS WITH DYSLIPIDEMIA Hiroaki Tanaka, R. Michishita, H. Kumahara, M. Ayabe, T. Tobina, E. Yoshimura, T. Matsuda, Y. Higaki, A. Kiyonaga, Fukuoka University Randomized Control Trial (FURCT), Japan 918 THE ROLE OF PHYSICAL ACTIVITY AND BROWN ADIPOSE TISSUE IN THE AMELIORATION OF METABOLIC SYNDROME DISORDERS IN HEREDITARY HYPERTRIGLYCERIDEMIC RATS Vojtech Skop, H. Malinska, J. Trnovska, M. Huttl, L. Kazdova, Czech Republic 1025 Session 25: CV RISK FACTORS 2 Moderator: Anne Tybjaerg-Hansen, Denmark M188 ANALYSIS OF THE BASAL DATA ON INTIMA-MEDIA THICKNESS OF THE SPANISH MULTICENTER PROSPECTIVE OBSERVATIONAL STUDY OF ATHEROMATOSIS IN CKD (NEFRONA) Àngels Betriu, M. Borràs, M. Martinez, J.M. Valdivielso, E. Fernández, and the Investigators of the Nefrona Study, Spain 498 M189 ARTERIAL STIFFNESS AND LP(A) LEVELS AS PROGNOSTIC FACTORS FOR FIRST-EVER ISCHEMIC STROKE IN A GREEK POPULATION SAMPLE Christina Voulgari, S. Tesfaye, C. Karagiannis, S. Paximadas, S. Pagoni, Greece, UK 312 M190 REDUCED 25-HYDROXYVITAMIN D CONCENTRATIONS AND INCREASED RISK OF VENOUS THROMBOEMBOLISM, MYOCARDIAL INFARCTION, AND ISCHEMIC STROKE Peter Brøndum-Jacobsen, M. Benn, A. Tybjærg-Hansen, B.G. Nordestgaard, Denmark 571 M191 MULTIMARKER APPROACH COMBINING BIOMARKERS OF HAEMOSTASIS, INFLAMMATION AND ENDOTHELIAL ACTIVATION, CHEMOKINES AND ADIPOCYTOKINES TO PREDICT ISCHAEMIC STROKE Christof Prugger, G. Luc, B. Haas, P.-E. Morange, J. Ferrieres, P. Amouyel, F. Kee, P. Ducimetiere, J.-P. Empana, France, UK 1261 54 Tuesday, June 4, 2013 13:40-14:40 Moderated Poster Area MODERATED POSTER SESSION C (contd.) Session 25: CV RISK FACTORS 2 (contd.) Moderator: Anne Tybjaerg-Hansen, Denmark Poster Board No. Abstract No M192 GENETICALLY REDUCED NONFASTING TRIGLYCERIDES AND REDUCED ALL-CAUSE MORTALITY M. Thomsen, A. Varbo, A. Tybjærg-Hansen, Børge Nordestgaard, Denmark1501 M193 IL-18 +183 A/G POLYMORPHISM, SINGLE AND IN COEXISTENCE WITH THE MMP-9 -1562 C/T POLYMORPHISM, ASSOCIATES WITH CLINICAL EVENTS IN CAD Trine Baur Opstad1,2, A.Å. Pettersen1,2, H. Arnesen2,3,4, I. Seljeflot1,2,4, Norway 555 M194 GENETIC DEFECTS IN PROTEIN GLYCOSYLATION AS CAUSE OF DYSLIPIDEMIA Adriaan G. Holleboom, G.K. Hovingh, M.M. Motazacker, G.M. DallingaThie, J.A. Kuivenhoven, H. Aerts, R. Wevers, E.S.G. Stroes, D.J. Lefeber, The Netherlands M195 896 THE NATURAL HISTORY OF CORONARY OBSTRUCTIONS IS INFLUENCED BY THE PRESENCE OF ADJACENT PROXIMAL OBSTRUCTIONS Masaya Tsuda, S. Takahashi, M.I. Papafaklis, A.P. Antoniadis, S. Mizuno, Y. Makita, S. Nakamura, S. Gohara, M. Shibata, A. Namiki, T. Matsumura, S. Tanaka, A.U. Coskun, S. Saito, C.L. Feldman, P.H. Stone, PREDICTION Study Investigators, USA, Japan 1521 55 Monday, June 3 – Wednesday, June 5, 2013 10:00-17:00 Poster Area Track 1 POSTERS TRACK 1: VASCULAR BIOLOGY OF THE ARTERIAL WALL Poster Board No. Abstract No Endothelial cells and function 1 BLOOD FLOW INVESTIGATION AT THE BOUNDARY LAYER IN ATHEROSCLEROSIS Merab Beraia, E. Beraia, Georgia 156 2 ASSOCIATION BETWEEN CIRCULATING ENDOTHELIAL PROGENITOR CELLS AND TRADITIONAL CARDIOVASCULAR RISK FAKTORS IN PATIENTS WITH CORONARY ARTERY DISEASE Alexander E. Berezin, A.A. Kremzer, Ukraine 267 3 RAPAMYCIN ATTENUATES ENDOTHELIAL CELL OXIDATIVE APOPTOSIS INDUCED BY LOW SHEAR STRESS THROUGH PROMOTION OF SESTRIN1 EXPRESSION VIA MTORC2 INHIBITION Junxia Zhang, Z. Wang, S. Chen, China 4 CLINICAL FEATURES OF PATIENTS WITH CRITICAL LIMB ISCHEMIA WHO RESPONDED TO AUTOLOGOUS MONONUCLEAR CELL TRANSPLANTATION FOR THERAPEUTIC ANGIOGENESIS Naoyoshi Aoyama, M. Nishinari, O. Shinichi, A. Kanai, N. Chiharu, M. Hirata, T. Izumi, Japan 318 5 HIGH DENSITY LIPOPROTEINS LIMIT NEUTROPHIL-INDUCED DAMAGE TO THE BLOOD BRAIN BARRIER IN VITRO Bao Quoc Dang, B. Lapergue1,2,3, A. Tran-Dinh1,2,3, D. Diallo, J.-A. Moreno1,4, M. Mazighi1,2,3, J.-B. Michel1,5, P. Amarenco1,2,3, O. Meilhac1,2,3, France, Spain 508 6 THE ROLE OF THE GLYCOCALYX IN ENDOTHELIAL CELL RESPONSE TO WALL SHEAR STRESS Karli McDonald, S. Cooper, P. Jonak, R.L. Leask, Canada 618 7 SEX DIFFERENCES IN MESENTERIC NITRIC OXIDE PRODUCTION AND NADPH OXIDASE MRNA EXPRESSION OF STREPTOZOTOCININDUCED DIABETIC RATS R. Zhang, X. Han, L. Anderson, Roshanak Rahimian, USA 639 8 RESEARCHING OF THE ENDOTHELIAL DYSFUNCTION MARKERS AND THE APOPTOSIS OF ENDOTHELIOCYTES DURING EXPERIMENTAL ATHEROSCLEROSIS IN A RAT MODEL Svetlana Kryvorot, T. Vladimirskaya, I. Sved, N. Moskaleva, Belarus 754 9 L-ARGININE INHIBITS ENDOTHELIAL CELL APOPTOSIS IN RABBIT MODEL OF HYPERCHOLESTEROLEMIA Shaghayegh Haghjooy Javanmard, M. Nematbakhsh, Iran 56 277 1032 POSTERS TRACK 1 VASCULAR BIOLOGY OF THE ARTERIAL WALL (contd.) Poster Board No. Abstract No 10 SYNDECAN-4 INTRACELLULAR DOMAIN ORCHESTRATES RANTES/CCL5-INDUCED ENDOTHELIAL CELL MIGRATION BY MODULATION OF PKC ACTIVATION Loic Maillard, V. Friand, N. Suffee, H. Hlawaty, O. Haddad, F. Chmilewsky, O. Oudar, N. Saito, L. Martin, D. Letourneur, N. Charnaux1,5, A. Sutton1,5, France, Japan 1052 11 MNA-INDUCED PGI2 RELEASE IN THE ISOLATED, PRESSURIZED AND PERFUSED CAROTID ARTERY Magdalena Sternak, B. Sitek, T. Wójcik, A. Broniec, B. Proniewski, A. 1072 Fedorowicz, S. Chłopicki1,2, Poland 12 ENDOTHELIAL SR-B1 LIMITS CEREBRAL INFARCTION IN A STROKE MODEL Alexy Tran-Dinh1,2,3, L. Varela-Perez, S. Gilibert4,5,6, B. Lapergue1,3, D. Diallo, L. Louedec, S. Delbosc, J.-B. Michel1,2,7, P. Amarenco1,2,3, T. Huby4,5,6, 1078 O. Meilhac1,2,3, France 13 UNCOUPLING OF ENOS IS RELATED TO ADMA ACCUMULATION IN THE ENDOTHELIUM ADJACENT TO ATHEROSCLEROTIC LESIONS Leszek Kalinowski, M. Stepnowska, A. Siekierzycka, M. Wozniak, A. Szeffler, L.W. Dobrcucki, J. Wojciechowski, J. Rogowski, I.T. Dobrucki, Poland, USA 1127 14 ENDOTHELIAL EXPRESSIONS OF ENDOGLIN AND ENOS DIFFER BETWEEN C57BL/6J AND C3H/HEJ MICE AFTER CHOLESTEROL DIET IMPLICATIONS IN ENDOTHELIAL DYSFUNCTION? Jana Pfeiferova, Z. Strasky, K. Jezkova, P. Nachtigal, Czech Republic 1213 15 ENDOTHELIAL RESPONSE TO SUNITINIB TREATMENT IN NORMOTENSIVE AND HYPERTENSIVE RATS - PILOT STUDY Ivana Nemeckova, O. Lencova, M. Sterba, P. Nachtigal, Czech Republic 1289 16 CHANGE OF CONCEPT ABOUT THE REGULATION OF MONOCYTE CHEMOATTRACTANT PROTEIN-1 PRODUCTION IN HUMAN ENDOTHELIAL CELLS STIMULATED WITH ANGIOTENSIN II María Isabel Castiñeiras-Landeira, B.K. Rodiño-Janeiro, B. ParadelaDobarro, S. Raposeiras-Roubín, M. González-Peteiro, R. Ucieda-Somoza, J.R. González-Juanatey, E. Alvarez, Spain 1372 17 DIFFERENTIAL EFFECTS OF EARLY GLYCATED PROTEINS AND ADVANCED GLYCATION END-PRODUCTS ON ENDOTHELIAL RESPONSES INVOLVED IN DIABETIC VASCULAR COMPLICATIONS Beatriz Paradela-Dobarro, B.K. Rodiño-Janeiro, J. Alonso, M.I. CastiñeirasLandeira, S. Raposeiras-Roubín, M. González-Peteiro, R. Ucieda-Somoza, J.R. González-Juanatey, E. Alvarez, Spain 1388 18 EFFECT OF ENDOTHELIAL PROGENITOR CELLS ON PLATELET ACTIVATION IN VITRO Vasilios Chantzichristos, F. Gkrozou, M. Paschopoulos, A. Tselepis, Greece 57 1460 POSTERS TRACK 1 VASCULAR BIOLOGY OF THE ARTERIAL WALL (contd.) Poster Board No. Abstract No 19 EFFECTS OF PURE TOCOTRIENOLS ON ENDOTHELIAL ACTIVATION IN PREVENTING EXPERIMENTALLY INDUCED SEVERE ATHEROSCLEROSIS Nurmazni Zulkafli, T.H. Abdul Rahman, N.K. Mohd Kornain, N.F. Hassim, A. Mohd Ismail, H. Mohd Nawawi, Malaysia 1491 20 LECITHIN:CHOLESTEROL ACYLTRANSFERASE DEFICIENCY IN MICE ALTERS ENDOTHELIAL FUNCTION Stefano Manzini, P. Cinquanta, C. Pinna, C. Parolini, M. Busnelli, L. Calabresi, G. Chiesa, G. Franceschini, Italy 1504 Endothelial dysfunction clinical assessment 21 INCREASED ASYMMETRIC DIMETHYLARGININE LEVEL IS THE MOST POWERFUL FACTOR ASSOCIATED WITH LOW HDL LEVELS IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION Julie Lorin, J.-C. Guilland, C. Korandji, Y. Cottin1,2, L. Rochette, C. Vergely, M. Zeller, France 17 22 SYMMETRIC DIMETHYLARGININE SERUM LEVEL AS A NEW MARKER OF LEFT VENTRICULAR EJECTION FRACTION IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION Julie Lorin, J.-C. Guilland, C. Korandji, P. Gambert, Y. Cottin1,3, L. Rochette, C. Vergely, M. Zeller, France 24 23 DYSLIPIDEMIA, ARTERIAL STIFFNESS AND ENDOTHELIAL DYSFUNCTION; UTILITY OF THE RADIAL ARTERY PULSE WAVE ANALYSIS Pablo Corral, F. Clara, G. Blanco, Argentina 41 24 ANALYSIS OF ARTERIAL FUNCTION IN ADULTS WITH A HISTORY OF KAWASAKI DISEASE Hisako Tobayama, H. Fukunaga, K. Takahashi, T. Furukawa, H. Oda, K. Akimoto, M. Kishiro, T. Shimizu, Japan 786 25 ENDOTHELIAL DYSFUNCTION AND AUTONOMIC NERVOUS SYSTEM ACTIVITY IN THE DEVELOPMENT OF CORONARY ARTERY DISEASE Tonka Kurteva, D. Somleva, N. Spasova, E. Kinova, A. Goudev, Bulgaria 959 26 FMD TEST RESULTS CAN PREDICT SPONTANEOUS AND EFFECTIVE PHARMACOLOGICAL REPERFUSION IN STEMI PATIENTS Anna Kalinskaya, I. Urazovskaya, E. Vasilieva, A. Shpektor, Russia 975 27 NON-INVASIVE DETECTION OF ENDOTHELIAL PERMEABILITY AND FUNCTION BY MRI Alkystis Phinikaridou, M.E. Andia, A. Protti, R.M. Botnar, UK 1014 28 SMALL LDL CHOLESTEROL CONCENTRATION IS A DETERMINANT OF ENDOTHELIAL DYSFUNCTION BY PERIPHERAL ARTERY TONOMETRY IN JAPANESE MEN Ryotaro Takahashi, K. Okumura, N. Taguchi, M. Suzuki, N. Ikeda, T. Murohara, Japan 1607 58 POSTERS TRACK 1 VASCULAR BIOLOGY OF THE ARTERIAL WALL (contd.) Poster Board No. 29 Abstract No THE EFFECT OF ENDOTHELIAL DYSFUNCTION BIOCHEMICAL MARKERS AND FLOW-MEDIATED DILATION ON THE PREDICTIVITY OF EXERCISE ECG Muhammed Sait Toprak, H. Sonmez, Z. Ozturk, H. Ekmekci, O.B. Ekmekci, H.A. Cakmak, B. Ikitimur, B. Karadag, B. Ilerigelen, Turkey 1610 Smooth muscle cells 30 NEUROPILIN ROLE IN THE DEVELOPMENT OF NEOINTIMAL HYPERPLASIA Caroline Pellet-Many, V. Mehta, I. Evans, J. Ruivo, I. Zachary, UK 446 31 EFFECTS OF A NOVEL BIOISOSTER OF FLAVONOIDS ON AORTIC SMOOTH MUSCLE CELL PROLIFERATION AND INFLAMMATION Cassandra Sentieri, C. Saponaro, S. Del Turco, S. Sartini, C. La Motta, G. Basta, Italy 482 32 S100A12 PROTEIN INDUCES THE PROLIFERATION AND CALCIFICATION OF VASCULAR SMOOTH MUSCLE CELLS Eiko Matsuoka, Y. Mori, A. Kosaki, Japan 542 33 TRANSCRIPTOME ANALYSIS IDENTIFIES NOVEL MECHANISMS OF CAMP-MEDIATED GROWTH ARREST IN VSMC: PKA AND EPAC SYNERGISE TO SUPPRESS EGR-1 EXPRESSION Tomomi Kimura-Wozniak, C. Hindmarch, M. Bond, UK 807 34 MECHANICAL STRETCH-INDUCED MMP-2 PRODUCTION REQUIRES ACTIVATION OF PDGFR-Β AND AKT IN VASCULAR SMOOTH MUSCLE Kyo Won Seo, J.U. Bae, Y.H. Kim, S.Y. Park, S.J. Lee, C.D. Kim, Republic of Korea 929 35 PLATELET ACTIVATING FACTOR ENHANCES MMP-2 PRODUCTION IN RAT AORTIC VASCULAR SMOOTH MUSCLE CELLS VIA Β-ARRESTIN2DEPENDENT ERK SIGNALING PATHWAY Yun Hak Kim, J. Bae, K.W. Seo, S.J. Lee, S.Y. Park, C.D. Kim, Republic of Korea 930 36 EXTRACELLULAR S100A4 PROMOTES ARTERIAL SMOOTH MUSCLE CELL PHENOTYPIC TRANSITION: IMPLICATION IN ATHEROSCLEROSIS AND RESTENOSIS Chiraz Chaabane, C.W. Heizmann, M.-L. Bochaton-Piallat, Switzerland 1013 37 NUCLEAR TARGETING OF APELIN IN VASCULAR SMOOTH MUSCLE CELLS: IMPLICATIONS IN CELL PROLIFERATION AND ATHEROSCLEROTIC PLAQUE FORMATION? Chiraz Chaabane, C. Brun, A. Roatti, Y. Audigier, A.J. Baertschi, M.-L. Bochaton-Piallat, Switzerland, France 1043 38 PARADOXICAL STIMULATION OF MATRIX METALLOPROTEINASE EXPRESSION BY BISPHOSPHONATES IN RAT VASCULAR SMOOTH MUSCLE CELL CULTURE Mehmet Zuhuri Arun, B. Reel, G.B. Sala-Newby, M. Bond, A.C. Newby, Turkey, UK 1048 59 POSTERS TRACK 1 VASCULAR BIOLOGY OF THE ARTERIAL WALL (contd.) Poster Board No. Abstract No 39 CALMODULIN EXPRESSION DISTINGUISHES THE SMOOTH MUSCLE CELL POPULATION OF THE HUMAN CAROTID PLAQUE Matteo Coen, G. Marchetti, P.M. Palagi, C. Zerbinati, G. Guastella, T. Gagliano, F. Bernardi, F. Mascoli, M.-L. Bochaton-Piallat, Switzerland, Italy 1082 40 INFLUENCE OF THE PHENOTYPE OF VASCULAR SMOOTH MUSCLE CELLS ON THE RENIN-ANGIOTENSIN SYSTEM IN RAT Sabrina Bennia, O. Lohez, G. Bricca, France 1528 41 EPAC 2 IS INVOLVED IN THE INFLAMMATORY RESPONSE OF TRANSDIFFERENTIATED AC8-EXPRESSING VASCULAR SMOOTH MUSCLE CELLS Amélie Vromman, N. Clément, K. Blirando, I. Limon, France 1570 42 HEAT SHOCK PROTEIN-60 MEDIATED INDUCTION OF VASCULAR SMOOTH CELL PROLIFERATION THROUGH NUCLEOCYTOPLASMIC TRAFFICKING Justin F. Deniset1,2, M. Hlaváčková, T.E. Hedley, M.N. Chahine, E. Dibrov, 1627 G.N. Pierce1,2, Canada 43 INTRINSIC SEROTONERGIC SYSTEM IN HUMAN CORONARY ARTERY SMOOTH MUSCLE CELLS: POTENTIAL IMPLICATION IN CORONARY ARTERY DISEASE Vithya Selvaraj, K. Baskar, S. Sur, D.K. Agrawal, USA 1642 44 THE EFFECTS OF ALENDRONATE ON CONTRACTILE RESPONSES IN HUMAN LEFT INTERNAL MAMMARY ARTERY Buket Reel, M. Arun, M. Guzeloglu, G. Albayrak, E. Hazan, Turkey 1220 Extracellular matrix and calcification 45 WALL PROPERTIES OF THE APOLIPOPROTEIN E-DEFICIENT MOUSE AORTA Aristotelis Agianniotis, N. Stergiopulos, Switzerland 182 46 PREVENTION OF CARDIAC EVENTS IN PATIENTS WITH ATHEROSCLEROSIS UNDERGOING VASCULAR OPERATIONS Elena Medvedeva, Y. Shchukin, E. Seleznev, Russia 272 EFFECT OF DIFFERENT TYPES OF PLAQUE ON HEMODYNAMIC CHANGES TO THE LEFT CORONARY ARTERY T. Chaichana, Zhonghua Sun, Australia 313 47 48 CHRONIC ANGIOTENSIN II INFUSION CHANGES MICRORNA PROFILE IN MURINE AORTAS Maria Gabriela Dulak, M. Siedlinski, T. Mikolajczyk, R. Nosalski, R. Korbut, A. Jozkowicz, T.J. Guzik, Poland 399 49 VITRONECTIN EXPRESSION IN AORTIC VALVES FROM SUBJECTS WITH SEVERE AORTIC STENOSIS M. Ledesma, L.M. Salazar-Pelaez, M. Correa, J.S. Jaramillo, S. Franco, Lina Maria Yassin-Norena, A.M. Herrera, Colombia 627 60 POSTERS TRACK 1 VASCULAR BIOLOGY OF THE ARTERIAL WALL (contd.) Poster Board No. Abstract No 50 DIFFERENTIAL GENE EXPRESSION IN CAROTID PLAQUES WITH CALCIFICATION Hiroyuki Katano1,2, K. Yamada, Japan 51 INTERPLAY OF INFLAMMATION AND OXIDATIVE STRESS IN HUMAN ABDOMINAL AORTIC ANEURYSMS Agnieszka Sagan, W. Mrowiecki, T. Mikolajczyk, K. Urbanski, G. Filip, B. Kapelak, T. Mrowiecki, R. Korbut, T. Guzik, Poland 868 52 ATHEROSCLEROSIS AND FIBRO-DYSPLASIA: TWO PATHOPHYSIOLOGICAL STREAMS INTO THE CALCIFIC AORTIC VALVE DISEASE. HOW COULD WE STEM THE DISEASE PROGRESSION? A. Vianello, S. Perlini, S. Cappelli, G. Palladini, A. Cerillo, D. della Latta, D. Chiappino, P. Tanganelli, M. Glauber, S. Berti, Annamaria Mazzone, Italy 884 53 ELASTIN PEPTIDES, NEW REGULATORS OF INSULIN RECEPTOR B. Romier-Crouzet, C. Kawecki, S. Baud, P. Maurice, L. Duca, L. Debelle, V. Durlach, Sebastien Blaise, France 948 54 CORONARY CALCIFICATION CORRELATES WITH VALVE AND ROOT CALCIFICATION IN ISOLATED AORTIC STENOSIS: AN EVIDENCE FOR CARDIAC-BASE CALCIFICATION DISEASE P. Hällgren, A. Holmgren, K. Sörensen, U. Näslund, K. Riklund, Michael Henein, Sweden 967 55 DEREGULATION OF SMOOTH MUSCLE CELL CYTOSKELETON WITHIN THE HUMAN ATHEROSCLEROTIC CORONARY MEDIA LAYER Fernando Vivanco, Spain 976 56 TLR ACCESSORY MOLECULE RP105 (CD180) IS INVOLVED IN POSTINTERVENTIONAL VASCULAR REMODELING AND SOLUBLE RP105 MODULATES NEOINTIMA FORMATION J.C. Karper, M.M. Ewing, M.R. De Vries, S.C.A. de Jager, E.G. Huizinga, J. Kuiper, J.W. Jukema, Paul Quax, The Netherlands 997 57 THE EFFECT OF PROLONGED SYSTEMIC DOXYCYCLINE THERAPY ON SERUM TISSUE DEGRADING PROTEINASES IN CORONARY BYPASS PATIENTS Hatem Alfakry, I. Kormi, P. Pussinen, J. Sinisalo, T. Sorsa, Finland 1036 58 ROLE OF S100A4 IN EARLY STAGE OF ATHEROSCLEROSIS AND ANEURYSM OF THE AORTA Ziad Touat, V. Ollivier, L. Louedec, K. Guedj, J.-B. Michel, G. Jondeau1,2, France 1096 59 ATHEROSCLEROTIC PLAQUES IN EX VIVO SYSTEM Anna Lebedeva, J.-C. Grivel, O. Ivanova, A. Shpektor, E. Vasilieva, L. Margolis, O. Ivanova, Russia, USA 60 687 1125 ZOLEDRONATE ATTENUATES ANGIOTENSIN II-INDUCED ABDOMINAL AORTIC ANEURYSM THROUGH INACTIVATION OF RHO/ROCK DEPENDENT JNK AND NF-KB PATHWAY Po-Hsun Huang, S.-H. Tsai, S.-J. Lin, Taiwan R.O.C. 1227 61 POSTERS TRACK 1 VASCULAR BIOLOGY OF THE ARTERIAL WALL (contd.) Poster Board No. Abstract No 61 FGF-23 AND CAROTID ATHEROSCLEROSIS: A DANGEROUS AFFAIR Angela Koverech, F. Del Porto, L. Ferri, C. Fantozzi, L. Rizzo, M. Taurino, M. Proietta, Italy 1259 62 PROTEOMIC ANALYSIS OF THE ELASTIC ARTERIAL MEDIA IN AGING Motoji Sawabe, S. Yoshida, A. Hamamatsu, T. Toda, T. Arai, M. Iwamoto, T. Endo, Y. Miura, Japan 1207 63 ROLE OF FIBRONECTIN EXTRA DOMAIN A IN CARDIOVASCULAR DISEASE: EVIDENCES FROM ANIMAL MODELS OF ATHEROSCLEROSIS V.K. Pulakazhi Venu, Giuseppe Danilo Norata1,2, P. Uboldi, A. Muro, L. Arnaboldi, A. Corsini, A.L. Catapano1,4, Italy 1300 64 WHOLE TRANSCRIPTOME SEQUENCING OF APOE-KO MOUSE AORTA REVEALS DIFFERENTIALLY EXPRESSED GENES IN ADVANCED ATHEROSCLEROSIS Stefano Manzini, M. Chiara, M. Busnelli, C. Parolini, G. Ganzetti, C.R. Sirtori, D.S. Horner, G. Chiesa, Italy 1522 65 EXTRACELLULAR MATRIX PROTEINS FROM PIG ARTERIES: FROM TISSUE TO BLOOD MARKERS OF ATHEROGENESIS Silvia Rocchiccioli, G. Pelosi, A. Cecchettini1,2, F. Viglione, M. Puntoni, L. Citti, O. Parodi, M.G. Trivella, Italy 1540 66 REGULATION OF ELASTIN SYNTHESIS IN AORTA THROUGH A CA2+ERK-DEPENDANT PATHWAY M. Lannoy, C. Choqueux, L. Louedec, Marie-Paule Jacob, France 1571 67 MMP-13 PREDOMINATES OVER MMP-8 AS THE FUNCTIONAL INTERSTITIAL COLLAGENASE IN MOUSE ATHEROMATA Thibaut Quillard, H.A. Araújo, Y. Tesmenitsky, P. Libby, USA 1647 Gene expression 68 MIR-21, -133B, -146A, -150, -155, -181B AND LET-7A ARE UPREGULATED IN ATHEROSCLEROTIC CORONARY VALVES FROM PATIENTS WITH AORTAL STENOSIS Jana Borucka1,2, J. Petrkova2,3, V. Lonsky, T. Tomankova, M. Petrek, Czech Republic 344 69 GENE EXPRESSION RESPONSES TO AORTAL ATHEROGENESIS T.A. Shchelkunova, I.A. Morozov, P.M. Rubtsov, L.M. Samokhodskaya, Igor 322 A. Sobenin4,5, A.N. Orekhov5,6, A.N. Smirnov, Russia 70 COORDINATION BETWEEN GENES EXPRESSION DURING ATHEROGENESIS T.A. Shchelkunova, I.A. Morozov, P.M. Rubtsov, L.A. Samokhodskaya, I.A. Sobenin4,5,6, Alrexander N. Orekhov5,6, A.N. Smirnov, Russia 323 62 POSTERS TRACK 1 VASCULAR BIOLOGY OF THE ARTERIAL WALL (contd.) Poster Board No. Abstract No 71 GENOME-WIDE EXPRESSION PROFILING HIGHLIGHTS THE ROLE PLAYED BY COMPLEMENT SYSTEM AND WNT PATHWAY DURING EARLY-STAGE ATHEROSCLEROSIS IN APOEKO MICE Marco Busnelli, S. Manzini, M. Chiara, C. Parolini, G. Ganzetti, C.R. Sirtori, D.S. Horner, G. Chiesa, Italy 1513 72 TRANSFORMING GROWTH FACTOR-BETA (TGF-ß) TRANSCRIPTIONAL REGULATION IN HUMAN CAROTID ATHEROMA: IN SILICO STUDY Nedra Dhaouadi, C. Paultre, P. Feugier, M.-P. Gustin, K. Kacem, J.-Y. Li, G. Bricca, C. Cerutti, France, Tunisia 1516 73 TRANSCRIPTIONAL ORGANIZATION AND FUNCTIONAL INTERACTIONS BETWEEN CORTICOIDS AND ANGIOTENSIN II SYSTEMS IN HUMAN ATHEROMA AND VASCULAR SMOOTH MUSCLE CELLS Hanene Ayari, L. Legedz, S. Barrot, P. Lantelme, P. Feugier, G. Bricca, O. Lohez, J.Y. Li, C. Cerutti, M.-P. Gustin, France 1519 74 ANNEXIN A5 INHIBITS ATHEROGENIC AND PRO-INFLAMMATORY EFFECTS OF LYSOPHOSPHATIDYLCHOLINE H. Domeij, X. Hua, J. Su, A. Bäcklund, Z. Yan, A. Frostegård, J. Haeggström, T. Modéer, Johan Frostegård, Sweden 1520 Infection and atherosclerosis 75 ASSOCIATION OF CHLAMYDIA PNEUMONIAE INFECTION WITH ATHEROGENIC LIPID PROFILE Hosseinali Habibinejad, A. Riahin, Iran 664 76 PERIODONTITIS IS CLOSELY ASSOCIATED WITH CAROTID ARTERIAL INFLAMMATION Sungeun Kim, H.-S. Seo, E.J. Kim, J.H. Na, J.H. Park, C.U. Choi, H.E. Lim, J.W. Kim, S.-W. Rha, C.-G. Park, D.J. Oh, Republic of Korea 689 77 MONO- AND POLYMICROBIAL PERIODONTAL PATHOGEN-INDUCED INFLAMMATORY CYTOKINE PROFILES IN HYPERLIPIDEMIC APOENULL MICE I. Velsko, S. Chukkapalli, M. Rivera, A. Lucas, Lakshmyya Kesavalu, USA1092 78 HIV INFECTION REDUCES THE CAPACITY OF HDL PARTICLES TO MEDIATE CHOLESTEROL EFFLUX FROM HUMAN MACROPHAGES Petra El Khoury, E.F. Villard, C. Legeai, G. Catalano, P. Yeni, C. Goujard, M. Guerin, France 1104 79 INDUCTION OF TOLL-LIKE RECEPTOR-2 MEDIATED INFLAMMATION IN HUMAN ATHEROMA DERIVED SMOOTH MUSCLE CELLS BY ORAL BACTERIA AND CHLAMYDIA PNEUMONIAE Tanja Pessi, L. Viiri, N. Astola, M. Pyysalo, K. Lounatmaa, A.H. Davies, T. Lehtimäki, P.J. Karhunen, C. Monaco, Finland, UK 1282 63 POSTERS TRACK 1 VASCULAR BIOLOGY OF THE ARTERIAL WALL (contd.) Poster Board No. Abstract No 80 MOLECULAR DETECTION OF BACTERIAL RNA IN ATHEROMATOUS PLAQUES OF PATIENTS WITH STROKE Macarena Gomez Lira, S. Ferronato, S. Olivato, A. Bertoncelli, S. Mazzucco, C. Signoretto, Italy 1353 81 DETECTION OF PERIODONTAL BACTERIA DNA IN CAROTID ATHEROSCLEROTIC PLAQUES. ASSOCIATION WITH THE HAPTOGLOBIN GENOTYPE Hélène Rangé1,2,3, M. Varret1,4, S. Delbosc, J.-B. Michel1,2,5, P. Bouchard2,3,6, 1455 O. Meilhac1,2,7, France 82 DETECTION OF HUMAN HERPES VIRUSES IN ATHEROSCLEROTIC LESION IN PATIENTS WITH CORONARY ARTERY DISEASE J.-C. Grivel, Elizaveta Nikitskaya, O. Ivanova, N. Ryazankina, N. Pinegina, A. Lebedeva, A. Shpektor, L. Margolis, E. Vasilieva, USA, Russia 1485 Inflammation 83 NADPH OXIDASE/ROS-DEPENDENT PYK2 ACTIVATION IS INVOLVED IN TNF-A-INDUCED MATRIX METALLOPROTEINASE-9 EXPRESSION IN RAT HEART-DERIVED H9C2 CELLS Chuen-Mao Yang, Taiwan R.O.C. 119 84 HIGH-CHOLESTEROL DIET STIMULATES 11Β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 IN ATHEROSCLEROTIC LESIONS OF APOE-DEFICIENT MICE L. Rehakova, P. Ergang, F. Kolar, R. Poledne, Jiri Pacha, Czech Republic 249 85 FLUVASTATIN SIGNIFICANTLY REDUCES LPS-STIMULATED INTERLEUKIN-6, BUT NOT INTERLEUKIN-1, IN THE STANDARD VASCULAR SMOOTH MUSCLE - MONOCYTE COCULTURE Harald Loppnow, C. Jaschke, H. Fu, K. Schlecht, S. Gielen, U. MüllerWerdan, H. Ebelt, M. Buerke, K. Werdan, Germany 298 86 ULTRASOUND EVIDENCE OF ATHEROGENESIS IN MOUSE LEMUR PRIMATES Fabien Chauveau, A. Sérusclat, E. Canet-Soulas, M. Wiart, J.-B. Langlois, R. Bolbos, F. Aujard, M. Perret, M. Dhenain, N. Nighoghossian, France 369 87 ACTIVATION OF Α7 NICOTINIC ACETYLCHOLINE RECEPTOR SUPPRESSES ATHEROSCLEROSIS Toshihiro Ichiki, T. Hashimoto, K. Sunagawa, Japan 474 88 MAPKAP 2/3: A NOVEL DRUG TARGET FOR CHOLESTEROL INDUCED CARDIOVASCULAR DISEASES IN VIVO? Naveed Akbar, M. Gaestel, J.J.F. Belch, F. Khan, UK, Germany 500 89 TRANSCRIPTIONAL LEUKOTRIENE PATHWAY ACTIVATION IN APOLIPOPROTEIN-E DEFICIENT MICE EXPOSED TO INTERMITTENT HYPOXIA: ROLE IN ATHEROSCLEROSIS PROGRESSION E. Gautier1,2, M. Bäck, C. Arnaud, M. Petri, P. Levy1,4,5, Françoise StankeLabesque1,2,5, France, Sweden 515 64 POSTERS TRACK 1 VASCULAR BIOLOGY OF THE ARTERIAL WALL (contd.) Poster Board No. 90 91 Abstract No ROLE OF INTERLEUKIN-6 IN АCUTE CORONARY SYNDROME Azizjon Abdumatlubovich Nizomov, Uzbekistan 523 DIETARY NITRATE REDUCES LEUKOCYTE ACTIVATION IN THE APOLIPOPROTEIN E KNOCKOUT MOUSE Rayomand S. Khambata, S.M. Ghosh, A. Ahluwalia, UK 574 92 LIPID BIOMARKERS PREDICT MONOCYTE POLARISATION AND CYTOKINE RELEASE IN HEALTHY CONTROLS John Fletcher, H. Williams, G. Cassorla, C. Wang, K. Hitos, N. Marmash, H. Medbury, Australia 684 93 TGFΒ BUT NOT BMPS ACTIVATES SMAD1/5 PATHWAY IN PRIMARY HUMAN MACROPHAGES AND INDUCES EXPRESSION OF PROATHEROGENIC GENES D. Nurgazieva, W. Ming, I. Ovsyi, A. Popova, N. Wang, Julia Kzhyshkowska3,4, A. Gratchev2,4, Russia, Germany 952 94 INCREASED INTERLEUKIN 9 IN ATHEROSCLEROTIC DISEASE Ida Gregersen, K. Holven2,3, M. Skjelland, S. Holm, L. Gullestad3,5, K. Krogh980 Sørensen3,6, P. Aukrust1,3,7, B. Halvorsen1,3, Norway 95 EMPHYSEMA ALONE DOES NOT EXPLAIN THE HIGHER RISK OF DEVELOPING ATHEROSCLEROSIS IN COPD PATIENTS: A ROLE FOR CHRONIC PULMONARY INFLAMMATION? P.P.S.J. Khedoe1,2, M.C. Wong1,2, I. Meurs, J.J. Plomp, G.T.M. Wagenaar, M. van Eck, L.M. Havekes1,6,7, P.C.N. Rensen, P.S. Hiemstra, Jimmy Berbée1,8, The Netherlands, Greece 1040 96 NLRP1-INFLAMMASOME, A KEY IN THE TURN OFF OF THE ENDOTHELIAL CELL TO THE PROINFLAMMATORY STATE OF THE PERIPHERAL ARTERIAL DISEASE Silvia Bleda, J. De Haro, C. Varela, I. Lopez de Maturana, J. Rodriguez, F. Acin, Spain 1081 97 LYSINE RICH CATIONIC PEPTIDES MAY ATTENUATE INFLAMMATION AND ATHEROSCLEROSIS Sampath Parthasarathy, A.N. Chandrakala, K. Selvarajan, USA 1148 98 POXYTRINS, A NEW FAMILY OF LIPOXYGENASE PRODUCTS FROM POLYUNSATURATED FATTY ACIDS, ARE DOTED OF ANTIATHEROTHROMBOTIC POTENTIAL Miao Liu, P. Chen, E. Véricel, T. Boussetta, F. Driss, M. Lagarde, M. Guichardant, France, China 1178 99 THE ANTIATHEROSCLEROTIC POTENTIAL OF VILDAGLIPTIN: THE CONCEPT OF ANTIINFLAMMATORY AND ANTIOXIDANT PROPERTIES Najah R. Hadi, S. Majeed, H. Abdelkadhem, A. Al-Jenabi, Iraq 1204 100 HIGH LEVELS OF COX-2 GENE EXPRESSION IN PERIPHERAL BLOOD OF CARDIOEMBOLIC COMPARED TO ATHEROTHROMBOTIC STROKE PATIENTS S. Ferronato, S. Olivato, C. Patuzzo, A. Scuro, P.F. Pignatti, S. Mazzucco, Macarena Gomez Lira, Italy 1322 65 POSTERS TRACK 1 VASCULAR BIOLOGY OF THE ARTERIAL WALL (contd.) Poster Board No. Abstract No 101 HIGH EXPRESSION OF ARACHIDONATE 15-LIPOXYGENASE AND PROINFLAMMATORY MARKERS IN HUMAN ISCHEMIC HEART TISSUE L.M. Hultén, Annika Lundqvist, L.U. Magnusson, C. Hermansson, A. Jeppsson, Sweden 1354 102 THEAFLAVINS-RICH FRACTION INHIBITS LIPOPOLYSACCHARIDESTIMULATED NUCLEAR FACTOR- ҠB ACTIVATION IN HUMAN ENDOTHELIAL CELLS Nur Hidayah Mohd Ishak, A. Mohd Ismail, G.R.A. Froemming, T.H. Abdul Rahman, H. Mohd Nawawi, Malaysia 1450 103 PERIVASCULAR INFLAMMATION IN HYPERTENSIVE RATS Ryszard Nosalski, T.P. Mikolajczyk, J. Maciag, T.J. Guzik, Poland 1582 Innate immunity 104 ASSOCIATION OF TOLL-LIKE RECEPTOR 4 WITH LUMINAL STENOSIS IN PATIENTS WITH STABLE ANGINA Bahador Bagheri, A. Garjani, B. Sohrabi, S. Mashayekhi, A. Movassaghpur, Iran 57 105 HYDROCORTIOSNE REDUCES MONOCYTE EXPRESSION AND RESPONSE OF TOLL-LIKE RECEPTOR 4 IN PATIENTS UNDERGOING PERCUTANEOUS CORONARY INTERVENTION Bahador Bagheri, A. Garjani, B. Sohrabi, S. Mashayekhi, A. Movassaghpur, Iran 127 106 NOD2 INDUCES COX2-MPGES-1-PGE2 AS PROXIMAL INNATE IMMUNE SIGNALING IN ATHEROSCLEROSIS H.-Q. Liu1,2, Xiao-Ying Zhang1,3, K. Edfeldt, M.M.O. Nijhuis, H. Idborg, M. Bäck, J. Roy, U. Hedin, P.-J. Jakobsson, J.D. Laman, D.P.V.D. Kleijn, G. Pasterkamp, G.K. Hansson, Z.-Q. Yan, Sweden, China, Netherlands Antilles 303 107 RECOVERY OF NATURAL KILLER CELLS IN PATIENTS WITH CORONARY ARTERY DISEASE. A ONE YEAR FOLLOW-UP STUDY Karin Backteman, J. Ernerudh, L. Jonasson, Sweden 332 5-LIPOXYGENASE PLAYS A CENTRAL ROLE IN TLR4-MEDIATED MONOCYTE ADHESION TO VASCULAR ENDOTHELIAL CELLS Chi Dae Kim, S.J. Lee, E.K. Choi, S.Y. Park, Republic of Korea 463 108 109 DIFFERENTIAL EXPRESSION OF GM1, A MARKER OF LIPID RAFTS, IN HUMAN MONOCYTE SUBPOPULATIONS MAY BE INVOLVED THE PATHOGENESIS OF ATHEROSCLEROSIS Valentina Shishkina, T. Pavlunina, M. Chelombitko, E. Gracheva, A. Kaminnyi, Y. Romanov, N. Samovilova, N. Prokazova, Russia 565 110 MODIFIED LIPOPROTEINS MODULATE DENDRITIC CELL IMMUNE FUNCTION Laure Perrin-Cocon1,2, O. Diaz1,2, P. André1,2,3, V. Lotteau1,2, France 992 SPLENIC DENERVATION ACCELERATES ATHEROSCLEROSIS IN APOE-/- MICE Marcus A. Ulleryd, P.A. Micallef, L.J. Yang, S. Hua, M.E. Johansson, Sweden 1003 111 66 POSTERS TRACK 1 VASCULAR BIOLOGY OF THE ARTERIAL WALL (contd.) Poster Board No. Abstract No 112 MACROPHAGIC VERSATILE OUTCOME IN CRITICAL CAROTID STENOSIS AND ACUTE AORTIC DISSECTION Livia Ferri, M. Proietta, C. di Gioia, L. Tritapepe, M. Leopizzi, C. Fantozzi, C. Chiappetta, I. Nofroni, C. Della Rocca, E. Marinari, A.P. Mitterhofer, A. Negro, A. Koverech, M. Taurino, F. Del Porto, Italy 1111 113 NATURAL KILLER CELL APOPTOSIS IN CORONARY ARTERY DISEASE: IS IT REFLECTED BY SOLUBLE APOPTOTIC MARKERS? Anna Lundberg, C. Evaldson, W. Li, K. Backteman, J. Ernerudh, L. Jonasson1,2, Sweden 1139 114 THE ROLE OF IKKΑ IN ATHEROSCLEROSIS Pathricia Tilstam, H. Noels, M. Gijbels, B. Zhou, W. Theelen, M. de Winther, C. Weber, Germany, Netherlands Antilles 1159 115 CHARACTERIZATION OF INVARIANT NATURAL KILLER CELL SUBSETS IN PATIENTS WITH FAMILIAL HYPERCHOLESTEROLEMIA Sergey Alexandrovich Bondarenko, A. Baragetti1,2, F. Pellegatta, A.L. 1269 Catapano1,3, G.D. Norata1,2, Italy 116 TLR4 -2604G>A VARIANT CONFERS DNA BINDING CAPACITY TO GATA FAMILY TRANSCRIPTION FACTORS, MODIFYING GENE EXPRESSION IN ATHEROSCLEROTIC PATIENTS PERIPHERAL BLOOD S. Ferronato, S. Olivato, M. Menegazzi, A. Scuro, M.G. Romanelli, E. Diani, S. Mazzucco, Macarena Gomez Lira, Italy 1283 117 THE NEURON-DERIVED ORPHAN RECEPTOR1 (NOR1) IS INDUCED IN HUMAN ALTERNATIVE MACROPHAGES AND CONTROLS THE EXPRESSION OF ALTERNATIVE POLARIZATION MARKERS Federica De Paoli, C. Copin, J. Vanhoutte, C. Zawadzki, B. Jude, S. Haulon, J. Eeckhoute, P. Lefebvre, B. Staels, G. Chinetti-Gbaguidi, Nuclear Receptors, Cardiovascular Diseases, Diabet, France 1291 118 PHENOTYPE CHANGES OF CIRCULATING BLOOD MONOCYTES (MN) IN THE HYPERCHOLESTEROLEMIC SWINE MODEL OF CORONARY ARTERY DISEASE (CAD) S. Sbrana, M.R. Puntoni, F. Viglione, G. Pelosi, Federico Vozzi3,4, M.G. Trivella, O. Parodi, Italy 1369 119 DISTRIBUTION OF M1 AND M2 MACROPHAGES SUBPOPULATIONS IN DIFFERENT TYPES OF CAROTID ATHEROSCLEROTIC PLAQUES Valentina S. Shishkina, M.A. Chelombitko, O.P. Ilyinskaya, E.M. Tararak, Russia 1391 120 INCREASING SURVIVAL OF MACROPHAGES DELAYS PROGRESSION OF ESTABLISHED ATHEROSCLEROTIC LESIONS Laura Bouchareychas, J. Pirault, F. Saint-Charles, E. Gautier, P. Giral, T. Huby, P. Lesnik, France 1402 67 POSTERS TRACK 1 VASCULAR BIOLOGY OF THE ARTERIAL WALL (contd.) Poster Board No. Abstract No Adaptive immunity 121 122 ACTIVE IMMUNIZATION AGAINST SULFATED GLYCOSAMINOGLYCANS AS A NOVEL THERAPEUTIC AVENUE IN ATHEROSCLEROSIS Katia Mellal, V. Brito, S.G. Portelance, A. Pérez, Y. Soto, D. deBlois, H. Ong, A.M. Vázquez, S. Marleau, Canada, Cuba 628 ROLE OF PI3K-C2BETA IN T LYMPHOCYTES DEVELOPMENT AND ATHEROSCLEROSIS Gianpaolo Tibolla1,2, S. Bertoni, F. Sala, G.D. Norata1,2, A.L. Catapano1,3, Italy 695 123 ATTENUATION OF EARLY ATHEROSCLEROSIC LESIONS IN A MURINE MODEL BY IMMUNOTOLERANCE WITH BETA-2-GLYCOPROTEIN AND THE IMMUNOMODULATORY EFFECTORS IL-2 AND IL-10 Joaquín De Haro, L. Esparza, C. Varela, S. Bleda, I. López-Maturana, J. Rodríguez, C. González, F. Acin, Spain 722 124 METHOTREXATE AND ETOPOSIDE, BOTH ASSOCIATED WITH LIPID NANOEMULSIONS, INCREASES FOXP3 T LYMPHOCYTES IN THE INTIMA OF HYPERCHOLESTEROLEMIC RABBITS Antonio Carlos de Arruda Leite Jr1,2, A. Bulgarelli, E.R. Tavares, R.C. Maranhão1,2, Brazil 901 125 LOSS OF B-CELL FUNCTION IN MRAS- KNOCK-OUT MOUSE AND REDUCED INFLAMMATION IN ATHEROSCLEROTIC PLAQUES AT THE AORTIC ROOT Jennifer Freyer1,2, M. Behrensen1,2, Z. Aherrahrou1,2, J.F.P. Berbée, H. 1133 Schunkert4,5, J. Erdmann1,2, Germany, The Netherlands 126 MCS-18 INHIBITS THE PROGRESSION OF ATHEROSCLEROSIS IN APOE-DEFICIENT MICE BY MODULATING THE IMMUNE RESPONSE Barbara Dietel, R. Münch, R. Altendorf, I. Cicha, A. Steinkasserer, E. Zinser, S. Achenbach, C. Garlichs, F. Kerek, Germany 1157 127 CD137 SIGNALING IN THE PATHOGENESIS OF ATHEROSCLEROSIS 1427 I.-H. Jung1,2, J. Jin, D.-Y. Kim, Goo Taeg Oh, Republic of Korea 128 CHARACTERIZATION OF MEMORY T CELL SUBSETS IN PATIENTS WITH FAMILIAL HYPERCHOLESTEROLEMIA Federica Sala, F. Pellegatta, A. Baragetti, G.D. Norata1,2, A.L. Catapano1,3, Italy 1462 68 POSTERS TRACK 1 VASCULAR BIOLOGY OF THE ARTERIAL WALL (contd.) Poster Board No. Abstract No Hormones and atherosclerosis 129 MEN WITH POOR CARDIORESPIRATORY FITNESS COMBINED WITH LOWER TESTOSTERONE HAVE HIGH OXIDIZED LDL LIPIDS - BEING FIT PREVENTS THIS RELATIONSHIP Jussi Kosola, M. Ahotupa, H. Kyrolainen, M. Santtila, T. Vasankari, Finland 117 130 THE THYROID HORMONE RECEPTOR TRΑ PROTECTS AGAINST ATHEROSCLEROSIS DEVELOPMENT: AN NEW ROLE FOR TRΑ AS AN ANTI-INFLAMMATORY FACTOR C. Billon, L. Canaple, J. Samarut, Karine Gauthier, France 224 131 EFFECT OF ESTRADIOL ON ATHEROSCLEROSIS OF THE COMMON CAROTID ARTERY IN WOMEN: A POSTMORTEM ANALYSIS Ho-Dirk Kim, Republic of Korea 467 132 INCREASED NEOINTIMAL FORMATION AFTER VASCULAR INJURY IN ANDROGEN RECEPTOR KNOCKOUT MICE Anna S. Wilhelmson, J. Bourghardt-Fagman, M.E. Johansson, K. De Gendt, G. Verhoeven, P. Fogelstrand, Å. Tivesten, Sweden, USA, Belgium 774 133 INVOLVEMENT OF P27 IN THE PROGESTERONE-INDUCED MIGRATION INHIBITION IN RAT AORTIC SMOOTH MUSCLE CELLS Hui-Jane Wang, S.-P. Hsu, S.-F. Chang, C. Hsu, W.-S. Lee, Taiwan R.O.C. 910 134 THE ROLE OF DISCOIDIN DOMAIN RECEPTOR SIGNALLING AND EFFECT OF ALENDRONATE IN CAROTID ARTERY LIGATION-INDUCED INTIMAL THICKENING IN MICE Buket Reel, S. Ozbal, B.U. Ergur, O. Yilmaz, D. Keles, G. Oktay, G. Sevin, Z. Kerry, Turkey 1228 69 POSTERS TRACK 2 LIPID AND LIPOPROTEIN METABOLISM: FROM ALTERATIONS TO TREATMENTS Poster Board No. Abstract No apoB-Containing lipoproteins / Modified lipoproteins 135 PROTEIN DISULFIDE ISOMERASE MODIFICATION BY OXIDIZED LDL IMPAIRS ITS FUNCTION AND CONTRIBUTES TO APOPTOSIS. A ROLE IN ATHEROSCLEROSIS? C. Muller, J. Bandemer, C. Vindis, R. Salvayre, Anne Negre-Salvayre, France 1123 136 ANTAGONISTIC EFFECTS OF IL-10 AND IL-6 ON LDL OXIDATION; PROBABLE EVIDENCE FOR A CYTOKINIC MODULATORY MECHANISM IN ATHEROGENESIS Adel Abedpour Dehkordi1,2, G.A. Naderi, H. Nayeri, M. Boshtam, N. Jafari Dinanai, Iran 415 137 MODIFIED ATHEROGENIC LDL INDUCES OVEREXPRESSION OF BOTH PRO-INFLAMMATORY CYTOKINE TNFA AND ANTI-INFLAMMATORY CHEMOKINE CCL18 Nikita G. Nikiforov1,2, Y.V. Bobryshev1,3,4, V. Aladinsky, E.N. Borodachev, O. Gorlova, A. Temchenko, N. Pervushina, I.A. Sobenin1,2,3, A.N. Orekhov1,3, Russia, Australia 674 apoB-Containing lipoproteins / Lp(a) 138 ELEVATED LIPOPROTEIN(A) IS ASSOCIATED WITH WORSE PROGNOSIS IN DIABETIC PATIENTS WITH CORONARY ARTERY DISEASE Sung Woo Kwon, J.-J. Cha, B.K. Lee, J.-Y. Kim, E.-Y. Choi, P.-K. Min, Y.W. Yoon, B.-K. Hong, S.-J. Rim, H.M. Kwon, Republic of Korea 71 139 EVALUATION OF HOMOCYSTEINE AND LIPOPROTEIN(A) PLASMA LEVELS CAN REVEAL ADVANCED SYSTEMIC ATHEROSCLEROTIC BURDEN IN ACUTE CORONARY SYNDROME PATIENTS Gabriele Cioni, R. Marcucci, A.M. Gori, S. Fedi, A. Galassini, E. Ganugi, A. Rogolino, C. Giglioli, S. Valente, G.F. Gensini, R. Abbate, M. Boddi, Italy 1083 140 LIPOPROTEIN (A) ANALYSES IN A FAMILY WITH PREMATURE CARDIOVASCULAR DISEASE Reyhana Yahya, R. Vongpromek, L. van der Zee, J. Touw, E. Sijbrands, A. Verhoeven, J. Roeters van Lennep, M. Mulder, The Netherlands 1469 HDL / CETP 141 HOW ANACETRAPIB INHIBITS THE ACTIVITY OF THE CHOLESTERYL ESTER TRANSFER PROTEIN? INSIGHT GAINED THROUGH ATOMISTIC SIMULATIONS Tarja Äijänen, A. Koivuniemi, T. Rog, I. Vattulainen, Biological Physics and Soft Matter Group, Finland 1436 142 ENDOGENOUS CETP ACTIVITY AS A PREDICTOR OF CARDIOVASCULAR RISK E.F. Villard, M.-C. Federspiel, V. Fesel-Fouquier, C. Cherfils, E. Bruckert, K. Clement, D. Bonnefont-Rousselot, W. Le Goff, R. Bittar, P. Couvert, Maryse Guerin, France 1046 70 POSTERS TRACK 2: LIPID AND LIPOPROTEIN METABOLISM: FROM ALTERATIONS TO TREATMENTS (contd.) Poster Board No. Abstract No 143 PLASMA CHOLESTERYL ESTER TRANSFER PROTEIN: A BIOMARKER FOR HEPATIC MACROPHAGES IN MICE AND HUMANS Yanan Wang, S.J.L. van der Tuin1,2, V. Bieghs, R. Shiri-Sverdlov, H.M.G. Princen, J.A. Romijn, M.G.M. Wolfs, S. Rensen, L.M. Havekes 1,4,7, M.H. Hofker, K. Willems van Dijk, P.C.N. Rensen, The Netherlands 847 144 ELEVATED CETP ACTIVITY IS ASSOCIATED WITH LOW, DYSFUNCTIONAL HDL IN SOUTH ASIANS Shirya Rashid, P. Power, M. Melone, Canada 145 195 HIGH CETP ACTIVITY IN MYOCARDIAL INFARCTION PREDICTS SHORT-TERM MORTALITY BY INDUCING ENDOTHELIAL DYSFUNCTION, POOR CORONARY FLOW AND MICROVASCULAR HYPOPERFUSION L.S. Carvalho, S. Santos, V.W. Virginio, F. Alexandre, Natalia B. Panzoldo, O. Nobrega, E.C. de Faria, J.C.Q. Silva, A.C. Sposito, Brazilian Heart Study, Brazil 1421 HDL / Cholesterol efflux 146 REGULATION OF ATP-BINDING CASSETTE TRANSPORTER A1 EXPRESSION IN RAW264.7 MACROPHAGES UNDER HYPERGLYCEMIC STRESS Anna Chiang, Y.-C. Chang, W.H.-H. Sheu, Y.-S. Chien, P.-C. Tseng, Taiwan R.O.C. 122 147 METABOLIC PHENOTYPING OF AN ENDOTHELIAL SPECIFIC ABCA1 KNOCKOUT MOUSE MODEL IN A NORMAL CHOW AND A HIGH CHOLESTEROL DIET Reda Hasballa, L. Rohrer, A. von Eckardstein, Switzerland 148 PI-3 KINASE- BUT NOR ERK1/2-MEDIATED SIGNALING PATHWAY IS INVOLVED IN BERBERINE-INDUCED ABCA1 MODULATION Francesca Zimetti, M.P. Adorni, S. Costa, N. Ronda, F. Bernini, E. Favari, Italy 1007 149 EFFECT OF ARECOLINE IN ATP-BINDING CASSETTE TRANSPORTER A1 EXPRESSION IN RAW 264.7 MACROPHAGE-DERIVED FOAM CELLS X.-P. Ouyang, Chao-Ke Tang, China 1328 150 EFFECT OF MUTANT APOA-I FORMS BOUND TO RECONSTITUTED HDL ON ABCG1-DEPENDENT CHOLESTEROL EFFLUX Georgios Daniil, V.I. Zannis, A. Chroni, Greece, USA 1366 ATHEROSCLEROTIC CELLS FOR ESTIMATION OF CHOLESTEROL EFFLUX Alrexander N. Orekhov1,2, I.A. Sobenin1,2,3, A.A. Melnichenko1,2, V.A. Orekhova1,3, Y.V. Bobryshev1,2,4, Russia, Australia 325 151 152 A SIMPLE METHOD TO MEASURE THE ABILITY OF PLASMA LIPOPROTEINS TO ACCEPT CHOLESTEROL FROM PLASMA MEMBRANES Antonio Carlos de Arruda Leite Jr1,2,3, D.L. Bispo, T.B. Moreira, J.C. dos Santos, R.C. Maranhão1,3, Brazil 71 385 821 POSTERS TRACK 2: LIPID AND LIPOPROTEIN METABOLISM: FROM ALTERATIONS TO TREATMENTS (contd.) Poster Board No. Abstract No HDL / Function and metabolism 153 FUNCTIONAL LIPID-PROTEIN CLUSTERS IN HUMAN PLASMA HDL: A SYSTEMS BIOLOGY APPROACH Ekaterina Chernova1,2, M. Lhomme, L. Camont, S. Chantepie, W. Le Goff, M.J. Chapman, A. Orekhov, W.S. Davidson, A. Kontush, France, Russia, USA 1550 154 A NOVEL HIGH-DENSITY LIPOPROTEIN ANTIOXIDANT CAPACITY ASSAY AND ITS APPLICATION TO HIGH-DENSITY LIPOPROTEIN FRACTIONS Krisztina Gaál, H. Lőrincz, I. Seres, M. Harangi, A.V. Oláh, G. Paragh, Hungary 832 155 LOW NORMAL FREE T4 CONFERS DECREASED HIGH DENSITY LIPOPROTEIN ANTI-OXIDATIVE FUNCTIONALITY IN THE CONTEXT OF HYPERGLYCEMIA Michela Triolo, J.F. de Boer, W. Annema, A. Kwakernaak, U. Tietge, R. Dullaart, The Netherlands 612 156 THE INVERSE RELATIONSHIP OF HDL ANTI-OXIDATIVE FUNCTIONALITY WITH SERUM AMYLOID IS ABSENT IN METABOLIC SYNDROME Robin P. Dullaart, J.F. de Boer, W. Annema, U.J. Tietge, The Netherlands 157 HDL-BINDING ANTIBODIES SELECTED FROM PHAGE ANTIBODY LIBRARY Janita Lövgren, N. Elonen, E.-C. Brockmann, T. Huovinen, K. Pettersson, M. Jauhiainen, U. Lamminmäki, Finland 1456 158 HIGH DENSITY LIPOPROTEINS FROM PATIENTS WITH LIPID TRANSFER ALTERATIONS AND CORONARY ARTERY DISEASE ARE ASSOCIATED WITH INCREASED PLATELET AGGREGATION Antonio Carlos de Arruda Leite Jr1,2,3, T.B. Moreira2,3, D.L. Bispo2,3, J.C. dos Santos2,3, M.C.O. Sprandel, A. Casella-Filho, W. Hueb, R.C. Maranhão1,3,4, Brazil 159 ENHANCED OXIDATIVE STRESS STATUS IN SUBJECTS WITH LOW HIGH-DENSITY LIPOPROTEIN CHOLESTEROL (HDL-C) IS NOT ASSOCIATED WITH LECITHIN CHOLESTEROL ACYLTRANSFERASE (LCAT) Farah Hanis Sakri, N.A. Mohd Mokhsin, T.H. Abdul Rahman, B.P. Hoh, A. Mohd Ismail, H. Mohd Nawawi, Malaysia 1448 160 WEARING THE HAT OF HIGH HDL CHOLESTEROL? Shamanna S. Iyengar, S. Chavan, N. Basha, India 161 96 820 190 HIGH PARAOXONASE 1 ACTIVITY STRENGTHENS HDL'S IN VITRO ANTI-OXIDANT FUNCTION IN STATIN TREATED DYSLIPIDEMIC PATIENTS AND IN HEALTHY SUBJECTS Rahul Yadav, Y. Liu, S. Kwok, V. Charlton-Menys, M. France, R. Eatough, S. Hama, N. Younis, B. Issa, B.J. Ammori, H. Soran, UK 1141 72 POSTERS TRACK 2: LIPID AND LIPOPROTEIN METABOLISM: FROM ALTERATIONS TO TREATMENTS (contd.) Poster Board No. Abstract No 162 LP A-I, LP A-II AND LP A-I/A-II IN THE PRE-BETA MOBILITY FRACTION, ARISING BY THE INTERACTION BETWEEN HDL AND LIPOSOMES Anna Wolska, M. Bednarek, K. Domitrz, A. Szutowicz, M. Wróblewska, Poland 123 163 ARE SMALL HDL PARTICLES PROTECTIVE IN CAROTID ATHEROSCLEROSIS ? D. Diallo, S. Delbosc, G. Lambert, Olivier Meilhac, France 1056 164 REGRESSION OF LUMINAL STENOSIS AT THE SITE OF SILENT PLAQUE DISRUPTION AND HIGH-DENSITY LIPOPROTEIN CHOLESTEROL Takayoshi Nemoto, K. Matsuo, Y. Ueda, Japan 1564 HDL / apoA1 functions 165 BOVINE APOLIPOPROTEIN (APO) A-I DEMONSTRATE ENHANCED ANTI-OXIDANT ACTIVITY WITH DIFFERENT STRUCTURE-FUNCTION CORRELATIONS RELATIVE TO HUMAN APOA-I G.-Y. Park1,2, S.-M. Kim1,2, Kyung-Hyun Cho1,2, Republic of Korea 308 166 SHORT TERM EFFECTS OF MDCO-216 (APOA-I MILANO WITH POPC) ON LIPIDS AND (APO)LIPOPROTEIN LEVELS IN CYNOMOLGUS MONKEYS Herman Kempen, M. Gomaraschi, L. Calabresi, S.E. Bellibas, P.L. Wijngaard, Switzerland, Italy, USA 181 167 STRUCTURAL PROPERTIES OF FUNCTIONAL HDL AND MILANO VARIANT OF APOA-I Jitka Petrlova, J. Dalla-Riva, L. Zhu, M. Mörgelin, H. Hebert, C. Jegerschöld, J.C. Voss, J.O. Lagerstedt, Sweden, USA 168 A PROTEOLIPOSOME CONTAINING V156K-APOA-I ENHANCES RAPID TUMOR REGRESSION ACTIVITY OF ONCOLYTIC ADENOVIRUS IN TUMOR-BEARING ZEBRAFISH AND MICE 676 J. Kim1,2, Kyung-Hyun Cho1,2, Republic of Korea 270 Intracellular metabolism 169 PHARMACOLOGICAL EVIDENCE FOR THE DOMINANT ROLE OF NEUTRAL CE HYDROLASE 1 IN THE HYDROLYSIS OF CE IN MURINE MACROPHAGES Kent Sakai, S. Nagashima, M. Takahashi, D. Yamamuro, H. Yagyu, J.-I. Osuga, S. Ishibashi, Japan 677 170 FARNESOID X RECEPTOR UP-REGULATES EXPRESSION FIBROBLASTGROWTH FACTOR 21 IN HEPG2 AND THE STUDY OF ITS MECHANISM* Yongchao Wang, H. Liu, J. Peng, Y. Zhang, J. Dong, X. Liu, Y. Jiang**, China 1214 73 POSTERS TRACK 2: LIPID AND LIPOPROTEIN METABOLISM: FROM ALTERATIONS TO TREATMENTS (contd.) Poster Board No. Abstract No 171 INTESTINAL RE-EXPRESSION OF APOA5 TROUGH DEMETHYLATION WITH 5-AZA-2′-DEOXYCYTIDINE OF ITS PROMOTER AND CPG ISLAND Montse Guardiola, A. Guillaumet, I. Oliva, R. Rosales, J.C. Vallvé, F. Sabench, D. Del Castillo, M. Esteller, D. Monk, J. Ribalta, Spain 1002 172 BIS(MONOACYLGLYCERO)PHOSPHATE PROTECTS FROM OXIDIZED LDL-INDUCED APOPTOSIS IN MACROPHAGES Maud Arnal, C. Costaz, I. Vandenbroucke, France 698 173 REGULATION OF LIPOGENIC PATHWAY BY LXR AGONISTS IN VASCULAR SMOOTH CELLS OF PSAMMOMYS OBESUS Nadjiba Hamlat Khennaf, S. Neggazi, S. Aouichat Bouguerra, M. Beylot, Algeria, France 1237 174 LIVER X RECEPTOR ACTIVATION DECREASES CHYLOMICRON ASSEMBLY AND IMPROVES POST-PRANDIAL TRIGLYCERIDEMIA VIA INTESTINAL SR-BI DOWNREGULATION Olivier Briand, S. Colin, V. Touche, A. Tailleux, V. Clavey, B. Staels, S. Lestavel, France 191 175 PREPONDERANT ROLE OF LXRΑ IN CHOLESTEROL EFFLUX FROM HUMAN FOAM CELLS THROUGH A SPECIFIC ABCA1-DEPENDENT PATHWAY Alexandre Superville, E. Frisdal, C.M. Quinn, M.-J. Kim, W. Jessup, M. Guerin, W. Le Goff, France, Australia 598 176 OXYPHYTOSTEROL FORMATION IN HUMANS; IDENTIFICATION OF HIGH AND LOW OXIDIZERS Sabine Baumgartner, R.P. Mensink, G. den Hartog, A. Bast, O. Bekers, U. Diczfalusy, C. Husche, D. Lütjohann, J. Plat, The Netherlands, Sweden, Germany 433 177 NATIVE LDL TRAFFICKING AND EFFECTS ON PRIMARY HUMAN MONOCYTE DERIVED MACROPHAGES N. Nikiforov, F. Li, N. Wang, M. Moisenovich, A.N. Orekhov1,4, Julia Kzhyshkowska2,4, Russia, Germany 859 Lipases and lipoprotein metabolism 178 A NEW ROUTINE ASSAY FOR REPRODUCIBLE LPL ACTIVITY MEASUREMENT IN POST HEPARIN PLASMA Mathilde Di Filippo1,2, C. Marçais2,3, M. Broyer, M. Merlin, A. Nollace, M. Delay, O. Marmontel, S. Charrière2,4, P. Moulin2,4, A. Sassolas1,2, France 1094 179 INCREASES OF SERUM MASS OF ENDOTHELIAL LIPASE IMPACT PLASMA HIGH-DENSITY LIPOPROTEIN-CHOLESTEROL CONCENTRATIONS IN ACUTE MYOCARDIAL INFARCTION Kenta Mori, T. Ishida, K. Miyashita, N. Kinoshita, H. Nakajima, T. Yasuda, R. Toh, M. Kawata, S. Sakamoto, K. Nakajima, K.-I. Hirata, Akashi KOBE study (AKB study) Group, Japan 1276 74 POSTERS TRACK 2: LIPID AND LIPOPROTEIN METABOLISM: FROM ALTERATIONS TO TREATMENTS (contd.) Poster Board No. Abstract No 180 HDL METABOLISM BY HTGL, EL AND LPL Katsuyuki Nakajima, K. Miyashita, N. Kinoshita, S. Imamura, T. Ishida, K. Hirata, T. Machida, H. Sumino, M. Nara, M. Murakami, Japan 1301 181 LOCALIZATION AND FUNCTION OF THE LIPOPROTEIN LIPASE SYSTEM IN MOUSE KIDNEY Rakel Nyrén, E. Vorrsjö, M. Ericsson, S. Nilsson, S. Kersten, G. Olivecrona, Sweden, The Netherlands 1466 182 CONTROL OF POSTPRANDIAL LIPEMIA BY CEREBRAL GLP-1 Thibault Deblache, C. Cabou, F. Reichardt, A. Colom, F. Tercé, R. Burcelin, X. Collet, France 1248 183 ROLE OF ENDOTHELIAL LIPASE IN HIGH-DENSITY LIPOPROTEIN METABOLISM IN HUMANS Tatsuro Ishida, K.-I. Hirata, Japan 1523 Lp-PLA2 184 A STUDY OF LIPOPROTEIN ASSOCIATED PHOSPHOLIPASE A2 (LPPLA2) AS AN EMERGING BIOMARKER IN CORONARY ARTERY DISEASE Saswati Das, S.K. Gupta, G. M.P., P.C. Ray, India 52 185 TREATMENT WITH BETABLOCKERS IS ASSOCIATED WITH LOWER LEVELS OF LP-PLA2 AND SUPAR IN CAROTID PLAQUES Giuseppe Asciutto, A. Edsfeldt, N.V. Dias, J. Nilsson, C. Prehn, J. Adamski3,4, I. Gonçalves2,5, Sweden, Germany 186 LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 LEVELS IS INFLUENCED BY CARDIAC DISEASE, EXTENSION OF ATHEROSCLEROSIS AND TREATMENTS Jean-Paul Charniot, R. Bittar, J.-P. Albertini, P. Giral, C. Cherfils, C. Cosson, E. Guillerm, P. Leprince, I. Gandjbakhch, D. Bonnefont Rousselot, France 416 187 INTEREST OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 IN THE PREOPERATIVE STATUS PRIOR AORTIC STENOSIS SURGICAL VALVE REPLACEMENT Jean-Christophe Charniot, R. Bittar, J.-P. Albertini, P. Giral, C. Cherfils, C. Cosson, E. Guillerm, P. Leprince, I. Gandjbakhch, D. Bonnefont Rousselot, France 420 188 PROGNOSTIC ROLE OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 ASSAYS IN PATIENTS WITH CARDIOGENIC SHOCK SYNDROME. A PILOT STUDY Jean-Christophe Charniot, R. Bittar, J.-P. Albertini, C. Cherfils, C. Cosson, E. Guillerm, D. Bonnefont Rousselot, France 437 189 COMPARING OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 SERUM LEVELS IN CORONARY ARTERY DISEASE PATIENTS DEPENDING ON DIABETES MELLITUS PRESENCE Anna Semenova, D. Nozadze, I. Sergienko, T. Vlasik, I. Rybalkin, Russia 75 359 559 POSTERS TRACK 2: LIPID AND LIPOPROTEIN METABOLISM: FROM ALTERATIONS TO TREATMENTS (contd.) Poster Board No. Abstract No 190 DECREASED ACTIVITY OF THE ANTI-ATHEROGENIC HDLASSOCIATED LPPLA2 AND INCREASED PROPORTION OF SMALL HDL3 PARTICLES IN SUBJECTS WITH IMPAIRED FASTING GLUCOSE T.D. Filippatos, E.C. Rizos, V. Tsimihodimos, A.D. Agouridis, E. Tzavella, Z. Mitrogianni, A.D. Tselepis, Moses S. Elisaf, Greece 696 191 ELEVATED LEVELS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 AMONG DIABETIC PATIENTS WITH CORONARY ARTERY DISEASE Aymen Bekir, M. Belhabib, M. Caslake, J. Cooney, A. Lewis, D. Bedford, H. Chahed, T. Trimech, K. Ben Hamda, F. Maatouk, S. Ferchichi, A. Miled, Tunisia, UK 709 192 PLASMA LP-PLA2 ACTIVITY IS RELATED TO PLAQUE STABILITY AS A POTENTIAL BIOMARKER FOR ACUTE CORONARY SYNDROME Byoung Kwon Lee, H. Chung, H.M. Kwon, Y. Yoon, E.-Y. Choi, Republic of Korea 797 193 THE USE OF LP-PLA2 MEASUREMENT AS A CARDIOVASCULAR „FINETUNER“ Ursula Kassner, T. Grenkowitz, E. Steinhagen-Thiessen, Germany 1113 194 EVEROLIMUS THERAPY IS ASSOCIATED WITH REDUCED LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 (LP-PLA2) ACTIVITY AND OXIDATIVE STRESS IN HEART TRANSPLANT RECIPIENTS Jerzy-Roch Nofer, K. Rosing, M. Fobker, F. Kannenberg, J. Stypmann, Germany 1163 195 CORONARY CALCIUM SCORE IS RELATED TO POLYMORPHISMS OF GENES OF PHOSPHOLIPASE A2 AND OF CHROMOSOME 9 A. Bertolami, C. Gonzaga, M. Sulzbach, D.B. Araujo, H. Zatz, Y. Nakamura, L. Wang, P. Lima, M. Hirata, A. Garofaro, A.A. Faludi, Marcelo Chiara Bertolami, Brazil 1167 Biomarkers / Lipid metabolism 196 MONITORING OF DIET-RELATED CHANGES OF THE PLASMA LIPIDOMICS PROFILE IN YOUNG HYPERCHOLESTEROLEMIC PATIENTS USING A MALDI-TOF-MS/MS APPROACH Gerald Stübiger, L. Hedjazi, M. Wuczkowski, O. Belgacem, K. Widhalm, Austria, France, UK 798 197 PLASMA PCSK9 IS A BIOMARKER OF SEVERITY IN PATIENTS WITH SEVERE TRAUMA INJURY Bertrand Cariou, M. Le Bras, A. Roquilly, F. Feuillet, V. Deckert, L. Lagrost, K. Asehnoune, P. Costet, France 869 198 CIRCULATING PCSK9 DISTRIBUTION IN RELATION TO AGE AND GENDER,AND ITS RELATION TO MARKERS OF CHOLESTEROL METABOLISM IN A SWEDISH COHORT Moumita Ghosh1,2, B. Angelin1,2, M. Rudling1,2, Sweden 76 999 POSTERS TRACK 2: LIPID AND LIPOPROTEIN METABOLISM: FROM ALTERATIONS TO TREATMENTS (contd.) Poster Board No. 199 Abstract No CHANGES IN THE FATTY ACID PROFILE OF ARTERIAL WALL AND BLOOD PLASMA IN PATIENTS WITH ATHEROSCLEROSIS Alexander Nikolaevich Osipenko, A.N. Osipenko, N.V. Akulich, Belarus 1389 Dyslipidaemia: epidemiology, biomarkers / HDL 200 201 DEVELOPMENT OF A NOVEL HOMOGENEOUS ASSAY FOR HDL SUBCLASSES Yasuki Ito, N. Sato, Japan 409 VALIDATION OF "BRINTON´S RATIO" FOR ESTIMATING HDL SIZE USING NMR-SPECTROSCOPY DATA FROM THE HIFUN STUDY Norman A. Mazer, E. Damonte, S. Rossomanno, M. Abt, R. Benghozi, Switzerland 691 202 HIGH DENSITY LIPOPROTEIN CHOLESTEROL, ANGIOGRAPHIC CORONARY ARTERY DISEASE, AND CARDIOVASCULAR MORTALITY Günther Silbernagel1,2, T.B. Grammer, H. Scharnagl, M.E. Kleber5,6, A. Ritsch, B.O. Boehm, U. Landmesser, W. März3,4,10, Germany, Austria, Switzerland 1165 203 RECENT HDL-C LEVEL OF JAPANESE GENERAL POPULATION INCREASED BY THE INTENSIVE LIFESTYLE MODULATION Koki Takata, Japan 1304 204 LOW CHOLESTEROL AND PHOSPHATIDYLCHOLINE PLASMA CONCENTRATIONS OF HDL SUBCLASSES IN SUBJECTS WITH HIGH CORONARY CALCIUM SCORE Oscar Pérez-Méndez, C. García-Sánchez, G. Vargas-Alarcón, C. PosadasRomero, Mexico 1418 205 CALCULATED LDL CHOLESTEROL BY FRIEDEWALD SUBSTANTIALLY UNDERESTIMATES LDL-C BELOW 70 MG/DL Evan Stein, S.M. Wasserman, I. Bridges, USA, UK 10 Dyslipidaemia: epidemiology, biomarkers 206 PREVALENCE OF SEVERE HYPERCHOLESTEROLEMIA IN A PREVENTIVE CARDIOLOGY CLINIC Jean Ferrières, D. Taraszkiewicz, J. Fourcade, S. Lemozy, D. Allemandou, V. Bongard, France 50 207 LIPID METABOLISM IN PERIMENOPAUSAL WOMEN WITH LOW TO MODERATE CARDIOVASCULAR RISK Anna Isayeva, M. Vovchenko, V. Volkov, I. Komir, Ukraine 208 RISK OF HYPERCHOLESTEROLEMIA ON CARDIOVASCULAR DISEASE AND POPULATION ATTRIBUTABLE FRACTION IN A 24-YEAR COHORT STUDY OF JAPANESE GENERAL POPULATION Daisuke Sugiyama, T. Okamura, T. Ohkubo, K. Miura, A. Okayama, H. Ueshima, NIPPON DATA 80/90 Research Group, Japan 465 77 319 POSTERS TRACK 2: LIPID AND LIPOPROTEIN METABOLISM: FROM ALTERATIONS TO TREATMENTS (contd.) Poster Board No. 209 Abstract No OXLDL TO OXLDL-AB RATIO - THE NEW BIOMARKER ASSOCIATED WITH CAROTID ATHEROSCLEROSIS AND CARDIOVASCULAR COMPLICATIONS IN DIALYZED PATIENTS Krystyna Pawlak, M. Mysliwiec, D. Pawlak, Poland 477 210 TRIGLYCERIDE/HDL RATIO, APOLIPOPROTEIN B, NON-HDL CHOLESTEROL ARE USEFUL PREDICTORS FOR LDL PARTICLE SIZE WITH STATIN TREATMENT IN CORONARY ARTERY DISEASE Sang-Hyun Kim, H.-L. Lee, D.-G. Park, K. Hack-Ryoung, J.-B. Seo, W.-Y. Chung, J.-H. Zo, M.-A. Kim, Republic of Korea 615 211 AGE AND SEXUAL ASPECTS OF THE HYPERCHOLESTEROLEMIA I.G. Leschenko, V.A. Leschenko, Roman Iosifovich Vorobyev, E.N. Vorobyeva, Russia 212 TRIGLYCERIDE IS A PREDICTOR OF HYPERTENSION IN AN 8-YEAR COHORT STUDY IN THE JAPANESE WORKERS Naomi Miyamatsu, A. Shima1,2, Y. Kawatsu, T. Nishikawa, D. Sugiyama, A. Kadota, A. Morimoto, Y. Tatsumi1,6, N. Sonoda, A. Morino, T. Okamura, Japan 705 213 A NON-RADIOMETRIC METHOD FOR ESTIMATION OF CHOLESTERYL ESTERS Hardik Gandhi, P. Pal, R. Giridhar, M.R. Yadav, India 1636 214 APOLIPOPROTEIN B:A1 RATIO IS INDEPENDENTLY ASSOCIATED WITH SUB-CLINICAL AND INCIDENT CORONARY HEART DISEASE IN BRITISH SOUTH ASIAN AND EUROPEAN MEN Therese Tillin, J. Heasman, A. Wright, P. McKeigue, A.D. Hughes, N. Chaturvedi, UK 739 215 IMPACT OF SEASONALITY ON THE PREVALENCE OF DYSLIPIDEMIA: A LARGE POPULATION STUDY E.S. Parra, A.C. Sposito, F. Moura, M.S. Dutra-Rodrigues, A. Cassol, V.H.D.S. Zago, F. Alexandre, I.V. Calanca, F. Vendrame, V.W. Virginio, F.K. Saraiva, O.R. Coelho, E. Naknadakare, E.C.R. Quintao, Eliana C. de Faria, Brazil 816 216 PREVALENCE OF DYSLIPIDEMIA IN OUTPATIENT CLINIC OF SAMARA CITY Mikhail A. Kachkovskii, V.V. Simerzin, I.M. Nazarkina, L.S. Fedoseeva, I.H. Sytdykov, E.R. Bulatova, O.A. Rubanenko, Russia 829 217 SMALL DENSE LDL AND OXIDIZED LDL ARE DIFFERENTLY ASSOCIATED WITH PROGRESSING ATHEROSCLEROSIS M. Budkhashvili, A. Sapegin, A. Titkov, S. Urazgildeeva, L. Vasina, Victor Gurevich, Russia 218 655 830 NOT ALL QUIET ON THE EASTERN FRONT. FAVORABLE CHANGES IN THE LIPID LEVELS OF PATIENTS WITH HIGH RISK IN HUNGARY Istvan Reiber, I. Mező, L. Márk, G. Paragh, G. Pados, I. Karádi, Z. Kiss, Hungary 863 78 POSTERS TRACK 2: LIPID AND LIPOPROTEIN METABOLISM: FROM ALTERATIONS TO TREATMENTS (contd.) Poster Board No. 219 Abstract No PROGNOSTIC VALUE OF APOLIPOPROTEIN B LEVEL IN PATIENTS WITH HEART FAILURE WHO SUFFERED ACUTE CORONARY SYNDROME Natalya Koziolova, E. Polyanskaya, Russia 935 LOW DENSITY LIPOPROTEIN SUBFRACTIONS IN PATIENTS WITH DIFFERENT GRADE OF CORONARY ATHEROSCLEROSIS Victoria A. Metelskaya, I.N. Ozerova, N.V. Perova, N.E. Gavrilova, O.I. Chernushevich, Russia 966 221 MARKERS OF SUBCLINICAL ATHEROSCLEROSIS - OXIDIZED LOW DENSITY LIPOPROTEINS Loreta Bagdonaite, Z.A. Kucinskiene, Lithuania 1006 222 ATHEROGENIC LIPID DISORDERS IN SIBERIAN ADOLESCENT POPULATION: PREVALENCE, TRENDS AND ASSOCIATIONS Diana Denisova, L. Zavyalova, Russia 1217 220 223 DEVELOPEMENT OF A REFERENCE METHOD FOR LDL-P AND PRODUCTION OF NEW REFERENCE STANDARDS IN LIPID TESTING: THE BIO-SITRACE PROJECT Vincent Delatour, M. Heuillet, B. Lalere, S. Vaslin-Reimann, H. Parkes, France, UK 1362 224 ESTIMATION OF SMALL DENSE LDL LEVEL USING THE SIMPLE PRECIPITATION METHOD IN TUNISIAN PATIENTS WITH CORONARY ARTERY DISEASE H. Aoua, A. Ben Khalfallah, Y. Nekaies, K. Charradi, M. Sakly, Nebil Attia, Tunisia 1376 225 DIFFERENT LIPOPROTEIN PROFILES IN EXAMINED INDIVIDUALS WITH DYSLIPOPROTEINEMIA IDENTIFIED BY LIPOPRINT SYSTEM Stanislav Oravec, J. Bulas, Ľ. Gašpar, A. Dukát, I. Vacula, Slovak Republic1499 226 HIGH SERUM REMNANT-LIKE LIPOPROTEIN PARTICLE CHOLESTEROL LEVELS ARE INDEPENDENTLY ASSOCIATED WITH INCREASED NECROTIC COMPONENTS IN CORONARY PLAQUES IN STATIN-TREATED PATIENTS Tetsuro Matsuoka, T. Matsuoka, A. Kato, Y. Makino, S. Kihara, Japan 1508 227 EXTENDED CHARACTERIZATION OF LIPIDIC PROFILE: EVALUATION OF LIPOPROTEIN SUBFRACTIONS F. Leitão, S. Berguete, S. Tania, G. Alexandra, Bourbon Mafalda1,2, Portugal 1568 Familial hypercholesterolaemia 229 ATYPIC ISOLATED GIANT XANTHOMAS ASSOCIATED WITH SEVERE MIXED DYSLIPIDEMIA WITHOUT FAMILIAL HYPERCHOLESTEROLEMIA Jean-Christophe Charniot, R. Bittar, A. Carrié, P. Couvert, R. Kidouche, O. Verola, E. Brucker, D. Bonnefont Rousselot, France 423 79 POSTERS TRACK 2: LIPID AND LIPOPROTEIN METABOLISM: FROM ALTERATIONS TO TREATMENTS (contd.) Poster Board No. Abstract No 230 PREVALENCE AND CHARACTERISTICS OF AUTOSOMAL DOMINANT HYPERCHOLESTEROLEMIA IN PERSONS SCHEDULED FOR CORONARY ANGIOGRAPHY. LUDWIGSHAFEN RISK AND CARDIOVASCULAR HEALTH STUDY (LURIC) Hubert Scharnagl, T.B. Grammer, M.E. Kleber, T. Stojakovic, U. Kassner, 431 E. Steinhagen-Thiessen, W. März1,2,4, Austria, Germany 231 SUBJECTS WITH FAMILIAL HYPERCHOLESTEROLEMIA ARE CHARACTERIZED BY A PRO-INFLAMMATORY PHENOTYPE DESPITE LONG-TERM INTENSIVE CHOLESTEROL-LOWERING TREATMENT Ingunn Narverud, P. Aukrust, H.W. Lindvig, B. Halvorsen, G. Langslet, L. Ose, K. Retterstøl, K.B. Holven, Norway 449 232 GENETIC DIAGNOSIS OF FAMILIAL HYPERCHOLESTEROLEMIA (FH) BY DIFFERENT NEXT GENERATION SEQUENCING PLATFORMS Marianne Stef, D. Arteta, E. Olano-Martin, N. Aizpuru, L. Grandoso, L. Alonso, J. Nieves, B. Sanz, X. Ugarte-Pedrero, X. Cantero, P. Galán-Garcia, I. Santos, L. Osaba, D. Tejedor, L. Palacios, Spain 576 233 PCSK9 GENETIC HETEROGENEITY IN FAMILIAL HYPERCHOLESTEROLEMIA (FH) PATIENTS L. Palacios, L. Grandoso, D. Arteta, A. Etxebarria2,3, C. Martin2,3, N. Aizpuru, L. Alonso, L. Osaba, D. Tejedor, Marianne Stef, Spain 586 234 DEFINING PATIENTS AT EXTREMELY HIGH RISK FOR CORONARY ARTERY DISEASEIN HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA Mariko Harada-Shiba, H. Makino, T. Okamura, I. Kishimoto, Y. Miyamoto, H. Tomoike, S. Yokoyama, Japan 643 235 BENEFICIAL EFFECT OF LDL-APHERESIS AND PLASMAPHERESIS ON PARAOXONASE CONCENTRATION AND LDL SUBCLASSES IN A PATIENT WITH SEVERE TYPE III HYPERLIPIDEMIA Mariann Harangi, I. Seres, M. Katkó, J. Padra, H. Lőrincz, G. Paragh, Hungary 667 236 NOVEL PCSK9 GENE VARIANT IN A FAMILIAL HYPERCHOLESTEROLAEMIA FAMILY FROM POLAND Malgorzata Walus-Miarka, M. Futema, B. Idzior-Waluś, M. Sanak, R.A. Whittall, K.W. Li, S.E. Humphries, Poland, UK 1500 237 COMMON PCSK9 VARIANT AS GENETIC BACKGROUND OF FAMILIAL COMBINED HYPERLIPIDEMIA IN JAPAN Atsushi Nohara, T. Noguchi, M.-A. Kawashiri, T. Inoue, S. Katsuda, M. Mori, C. Nakanishi, K. Yagi, A. Inazu, M. Yamagishi, H. Mabuchi, Japan 880 238 WOLMAN DISEASE: THE IMPORTANCE OF EARLY DIAGNOSIS. A REVIEW OF 6 CASES WITH COMPLETE LYSOSOMAL ACID LIPASE DEFICIENCY Pascale Benlian, A. Pagnier, K. Mention, F. Feillet, T. Levade, D. Plantaz, P. De Lonlay, V. Valayannopoulos, France 905 80 POSTERS TRACK 2: LIPID AND LIPOPROTEIN METABOLISM: FROM ALTERATIONS TO TREATMENTS (contd.) Poster Board No. Abstract No 239 AMINOTRANSFERASE ELEVATIONS OBSERVED IN A PHASE 3 STUDY OF PATIENTS WITH HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA TREATED WITH LOMITAPIDE WERE CLINICALLY MANAGEABLE Marina Cuchel, E.A. Meagher, D.J. Blom, H.D.T. Theron, A.D. Marais, R.A. Hegele, M.R. Averna, C.R. Sirtori, P.K. Shah, D. Gaudet, C. Stefanutti, G.B. Vigna, A.M. Du Plessis, L.T. Bloedon, D.J. Rader, USA, South Africa, Canada, Italy 915 240 CLINICAL VERSUS MOLECULAR DIAGNOSIS OF FAMILIAL HYPERCHOLESTEROLEMIA Mahtab Sharifi, A. Nair, D. Harvey, S.E. Humphries, D. Nair, UK 1150 241 A LARGE PROPORTION OF PATIENTS WITH FAMILIAL HYPERCHOLESTEROLEMIA ARE UNDER-TREATED: RESULTS OF A CROSS SECTIONAL STUDY IN 1757 FRENCH PATIENTS Sophie Béliard, V. Carreau, A. Carrié, P. Giral, E. Duchêne, M. Farnier, J. Ferrières, A. Fredenrich, M. Krempf, G. Luc, P. Moulin, E. Bruckert, France 1211 242 PREGNANCY IN HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA - WHEN THE THINGS ARE GOING WELL M. Blaha, M. Lanska, Vladimir Blaha, L. Boudys, I. Zimmerova, Czech Republic 1387 243 SECRETORY PHOSPHOLIPASE A2 ACTIVITY IN CHILDREN WITH HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA AND TWOYEAR EFFICACY OF PRAVASTATIN Marjet Braamskamp, S. Tsimikas, A. Wiegman, J. Kastelein, B. Hutten, The Netherlands, USA 1538 244 PATHOGENICITY ASSESSMENT OF LDLR VARIANTS IN PATIENTS WITH FAMILIAL HYPERCHOLESTEROLEMIA Ana Margarida Medeiros1,2, A.C. Alves1,2, A. Extebarria, C. Martin, Portugal, Spain 1541 245 APOB: OLD GENE, NEW PERSPECTIVE FOR FAMILIAL HYPERCHOLESTEROLAEMIA Ana Catarina Alves1,2, A. Extebarria, C. Martin, M. Bourbon1,2, Portugal, Spain 246 1542 P450 OXIDOREDUCTASE (POR) *28 ALLELE IS ASSOCIATED WITH LIPID LOWERING RESPONSE TO ATORVASTATIN IN CHILDREN AND ADOLESCENTS WITH FAMILIAL HYPERCHOLESTEROLEMIA G. Ragia, E. Drogari, V. Kolovou, L. Elens, V. Mollaki, A. Tavridou 1,5, R. van Schaik, G. Kolovou, Vangelis George Manolopoulos1,5, Greece, The Netherlands 1569 Primary dyslipidaemia 247 FAMILIAL COMBINED HYPERLIPIDEMIA: SHOULD WE CONSIDER IT IN PEDIATRICS? Francesca Abello, P. Cagliero, O. Guardamagna, Italy 1026 81 POSTERS TRACK 2: LIPID AND LIPOPROTEIN METABOLISM: FROM ALTERATIONS TO TREATMENTS (contd.) Poster Board No. Abstract No 248 OCCURRENCE OF TYPE V HYPERCHYLOMICRONEMIA IN DYSBETALIPOPROTEINEMIC PATIENTS: A CASE CONTROL STUDY Audrey Garon, C. Marcais, M. Di-Filippo, S. Charriere, A. Sassolas, P. Moulin, France 1087 249 TREATMENT OF EXTREME HYPERTRIGLYCERIDEMIA IN ZIEVE´S SYNDROME. A CASE REPORT Ioannis Terzis, T. Bitsis, I. Mallias, E. Papastefanou, T. Milidis, Greece 1234 LIPOPEROXIDATION IN CHRONIC PANCREATITIS - PRELIMINARY DATA Marek Vecka1,2, A. Žák1,2, L. Vávrová1,2, J. Kodydková1,2, J. Macášek, M. Urbánek, T. Krechler, B. Staňková1,2, Czech Republic 1577 250 251 MTTP MUTATIONS Y528H, R540C AND N649S ARE ASSOCIATED WITH ABETALIPOPROTEINEMIA AND REDUCE IN VITRO MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN ACTIVITY S.A. Miller, J.R. Burnett1,2, F.M. van Bockxmeer1,2, Amanda J. Hooper1,2, Australia 402 252 A NEW CASE OF FAMILIAL COMBINED HYPOLIPIDEMIA (FHBL2) WITH NEW HOMOZYGOUS ANGPTL3 MUTATION AND ABNORMAL ORAL FAT LOAD Mathilde Di Filippo1,2, O. Marmontel1,2, P. Moulin2,3, S. Charrière2,3, A. Sérusclat, L. Perrot, S. Nony, S. Dumont, D. Bozon, A. Sassolas1,2, France 1089 253 A CASE OF TANGIER DISEASE RESTRICTED TO VERY LOW HDL-C AND CHD Diana Muačević-Katanec, A. Merkler, A. Carrié, M. Barešić, M. Vučić, Ž. Reiner, P. Couvert, Croatia, France 1638 254 CLINICAL AND BIOCHEMICAL ASPECTS OF PSEUDOHYPERTRIGLYCERIDEMIA RESULTING FROM HYPERGLYCEROLEMIA P. Giral1,2, Randa Khani Bittar2,3, V.F. Fouquier, D. Rosenbaum, C. Vatier, 1059 B. Hansel, D.B. Rousselot3,5, France Secondary dyslipidaemia 256 OXIDIZED LOW DENSITY LIPOPROTEIN CONCENTRATION IS ASSOCIATED WITH THYROTROPIN LEVELS IN EUTHYROID NORMOCHOLESTEROLEMIC SUBJECTS Gustavo Giunta, G. Duaip, D. Rojo, G. Yannarelli1,2, N. Pacienza1,2, L. Maggi, L. Cuniberti1,2, Argentina 772 257 SUBCLINICAL THYROID DYSFUNCTION AS A PROGNOSTIC FACTOR FOR FIRST-EVER ISCHEMIC STROKE Christina Voulgari, L. Moulopoulos, A. Kanellou, V. Giannopoulou, A. Anagnostopoulos, S. Pagoni, Greece 1317 258 EARLY MARKERS OF ATHEROSCLEROSIS IN HYPOTHYROID WOMEN WITH ARTERIAL HYPERTENSION O. Mitchenko, Maksym Gvozdyk, V. Romanov, Ukraine 1145 82 POSTERS TRACK 2: LIPID AND LIPOPROTEIN METABOLISM: FROM ALTERATIONS TO TREATMENTS (contd.) Poster Board No. Abstract No 259 STIMULATION OF HUMAN CHOLESTEROL AND LIPOPROTEIN METABOLISM IN HYPERTHYROIDISM: IMPORTANCE OF LIVERSPECIFIC HORMONE ACTIONS Ylva Bonde1,2, O. Breuer, D. Lütjohann, S. Sjöberg, B. Angelin1,2, M. Rudling1,2, Sweden, Germany 260 HIV PROTEASE INHIBITORS INDUCE PREMATURE SENESCENCE AND CALCIFICATION OF VASCULAR SMOOTH MUSCLE CELLS IN VITRO Pauline Afonso, M. Auclair, C. Vigouroux, M. Caron-Debarle, France 1545 261 LIPID PROFILE AND ACHIEVEMENT OF LIPIDS GOALS AMONG HIVINFECTED PATIENTS COMPARED TO HIV-UNINFECTED PATIENTS AFTER ACUTE CORONARY SYNDROME Franck Boccara1,2, J. Miantezila Basilua, M. Mary-Krause, S. Lang, D. Costagliola, M. Guiguet, A. Cohen, France 1240 262 PSORIASIS ALTERS HDL COMPOSITION AND FUNCTION Gunther Marsche, P. Wolf, M. Holzer, Austria 396 1279 Genetics / HDL metabolism 263 ABCA1 GENE POLYMORPHISMS IN CORONARY ARTERY DISEASE Arzu Ergen, S. Isbir, H. Karagedik, T. Isbir, Turkey 131 264 ASSOCIATION OF THE G30S MUTATION OF LECITHIN: CHOLESTEROL ACYLTRANSFERASE (LCAT) WITH AN INCREASE OF CORONARY STENOSIS IN A TUNISIAN POPULATION J. Rejeb, Asma Omezzine, I. Boumaiza, L. Rebhi, A. Moussa, S. Kacem, N. Ben Rejeb, A. Ben Abdelaziz, E. Boughzala, A. Bouslama, Tunisia 490 265 ASSOCIATIONS OF ABCA1, CETP, APOAI, SCARB1, PON1, PON2 AND LCAT POLYMORPHISMS WITH CORONARY STENOSIS IN A TUNISIAN POPULATION J. Rejeb, Asma Omezzine, I. Boumaiza, L. Rebhi, A. Moussa, N. Ben Rejeb, A. Ben Abdelaziz, E. Boughzala, A. Bouslama, Tunisia 496 266 INFLUENCES OF ABCG1, ABCG5 AND ABCG8 SINGLE NUCLEOTIDEPOLYMORPHYSMS ON PLASMA LIPIDS AND LIPOPROTEINS OF A REPRESENTATIVE BRAZILIAN POPULATION Vanessa Helena De Souza Zago, E.S. Parra, N.B. Panzoldo, D.Z. Scherrer, J.H.G. Colletes, E.I.L. Gomes, V.S. Nunes, E. Nakandakare, E.C.R. Quintao, E.C. de Faria, Brazil 826 Genetics / Lipid metabolism 267 SMOKING, APOLIPOPROTEIN E GENOTYPES AND MORTALITY (THE LUDWIGSHAFEN RISK AND CARDIOVASCULAR HEALTH STUDY) Tanja Grammer, M.M. Hoffmann, H. Scharnagl, M.E. Kleber, G. Silbernagel, S. Pilz, A. Tomaschitz, E. Lerchbaum, R. Siekmeier, W. März 1,3,8, Germany, Austria 234 83 POSTERS TRACK 2: LIPID AND LIPOPROTEIN METABOLISM: FROM ALTERATIONS TO TREATMENTS (contd.) Poster Board No. Abstract No 268 THE INFLUENCE OF CETP, LPL AND APO CIII POLYMORPHISMS ON POSTPRANDIAL LIPEMIA Katherine Anagnostopoulou, C. Mihas, V. Kolovou, D. Manolopoulou, K. Sorontila, S. Lekka, P. Kostakou, D. Damaskos, D.V. Cokkinos, G. Kolovou, Greece 451 269 APOLIPOPROTEIN E GENOTYPE AND PROTEIN LEVEL, DEMENTIA AND CEREBROVASCULAR DISEASE - A STUDY OF 76,000 INDIVIDUALS FROM THE GENERAL POPULATION Katrine L. Rasmussen, A. Tybjærg-Hansen, B.G. Nordestgaard, R. FrikkeSchmidt, Denmark 564 270 THE RELATIONSHIP BETWEEN THE LEVELS OF SPLA2-IIA, VARIATION IN THE SPLA2-IIA GENE AND THE SEVERITY OF CORONARY ATHEROSCLEROSIS Tatyana Olegovna Pavlunina, Y.A. Shuvalova, Z. Khasanova, E.V. Samoylova, A.A. Korotaeva, V.V. Kukharchuk, A.I. Kaminnyi, Russia 271 ASSOCIATION OF PCSK9 GENE POLYMORPHISMS WITH THE RISK OF CORONARY ARTERY DISEASE IN THAI Parnsak Pitivej Thurakit, C. Settasatian, N. Settasatian, N. Komanasin, P. Intharapetch, U. Kukongwiriyapan, K. Tantipanichteerakul, V. Senthong, Cardiovascular Research Group, Khon Kaen University, Thailand 831 272 ASSOCIATION OF GENETIC VARIABILITY AT LDLR PROMOTER AND PRIMARY HYPERCHOLESTEROLEMIA Isabel De Castro-Orós1,2, J. Pérez-López, R. Mateo-Gallego2,4, M. Ledesma5,6,7, M. León6,7, M. Cofán, J.A. Casasnovas6,7, E. Ros, J.C. Rodríguez-Rey, F. Civeira, M. Pocoví1,7, Spain 986 273 THE PNPLA3 I148M VARIANT IS ASSOCIATED WITH HIGHER PREVALENCE OF TYPE 2 DIABETES IN SUBJECTS WITH METABOLIC SYNDROME Laura D'Erasmo, L. Polimeni, F. Baratta, A. Di Costanzo, N. Virga, M. Maranghi, M. Del Ben, F. Angelico, M. Arca, Italy 994 274 THE POLYMORPHISM OF APOLIPOPROTEIN CIII GENE AND LIPID PROFILE IN CAUCASIAN POPULATION OF WEST SIBER E. Shakhtshneider, I. Kulikov, V. Maksimov, Y. Nikitin, S. Malyutina, Mikhail Voevoda, Russia 1110 275 THE POLYMORPHISM OF APOLIPOPROTEIN E GENE AND LIPID PROFILE IN CAUCASIAN POPULATION OF WEST SIBERIA Mikhail Voevoda, E. Shakhtshneider, I. Kulikov, V. Maksimov, M. Ivanova, Y. Nikitin, S. Malyutina, Russia 1114 276 HPA1 GENE POLYMORPHISM IN APOLIPOPROTEIN C1 GENE IS ASSOCIATED WITH TYPE II DIABETES IN CAD PATIENTS Yann Pucheu, X. Pillois, A. Horovitz, A. Reynaud, J. Bonnet, France 84 567 1121 POSTERS TRACK 2: LIPID AND LIPOPROTEIN METABOLISM: FROM ALTERATIONS TO TREATMENTS (contd.) Poster Board No. Abstract No 277 GENOTYPIC INTERACTIONS OF GENES IMPLICATED IN LIPOPROTEIN METABOLISM WITH TYPE 2 DIABETES IN TUNISIAN POPULATION Raja Chaaba, S. Mehri, N. Attia, S. Hammami, M. Smaoui, K. Ben Hamda, A. Nakbi, N. Koubaa, M. Hammami, Tunisia 1185 278 ASSOCIATION OF HEPATIC LIPASE -514T ALLELE WITH CAD AND ANKLE-BRACHIAL INDEX, DEPENDENCE ON THE LIPOPROTEIN PHENOTYPE: THE GENES STUDY Céline Verdier, J.-B. Ruidavets, V. Bongard, D. Taraszkiewicz, L. Martinez, 1231 M. Elbaz1,3, J. Ferrières2,3, B. Perret, France 279 LDL RECEPTOR EXPRESSION AND FUNCTIONAL POLYMORPHISMS OF MMP 1 GENE IN CORONARY ARTERY DISEASE Kodapalli Mrudula Spurthi, G. Rajesh Kumar, G. Kishor Kumar, K. Sanjib Sahu, N. Prathiba, H. Surekha Rani, India 1626 280 ASSOCIATION OF HAPLOTYPES IN THE 3'UTR OF THE LDLR GENE WITH LOW-DENSITY LIPOPROTEIN LEVELS IN A BLACK SOUTH AFRICAN POPULATION Tertia Van Zyl, G.W. Towers, K.R. Conradie, J.C. Jerling, South Africa 1644 Lipid-lowering therapy / Ezetimibe 283 EFFECTS OF EZETIMIBE (EZE), SIMVASTATIN (SIMVA) AND EZETIMIBE/SIMVASTATIN (EZE/SIMVA) ON APOB, LDL-C AND NONHDL-C TARGETS IN PATIENTS WITH PRIMARY HYPERCHOLESTEROLEMIA Michel Farnier, J.R. Guyton, E. Jensen, A.B. Polis, A.O. Johnson-Levonas, P. Brudi, France, USA 120 284 EFFECTS OF EZETIMIBE, EZETIMIBE COADMINISTERED WITH STATINS AND STATIN THERAPIES ON FASTING GLUCOSE CHANGES IN PATIENTS WITH HYPERCHOLESTEROLEMIA P.P. Toth, A. Catapano, M. Farnier, J. Foody, Joanne E. Tomassini, E. Jensen, A.B. Polis, T. Musliner, A.M. Tershakovec, USA, Italy, France 196 285 VARIABILITY OF THE LDL-C LOWERING RESPONSE TO STATINS AND EZETIMIBE + STATIN THERAPY IN HYPERCHOLESTEROLEMIC PATIENTS O Descamps, J. Lin, J.E. Tomassini, A.B. Polis, A. Shah, P. Brudi, A.M. Tershakovec, Belgium, USA 201 286 EZETIMIBE IMPAIRS ENDOTHELIAL TURNOVER IN STABLE PATIENTS AT HIGH CARDIOVASCULAR RISK WITH ELEVATED C-REACTIVE PROTEIN L.C. Lins, C.N. França, F.A. Fonseca, S.P. Barbosa, A.C. Aguirre, H.T. Bianco, J.B. Amaral, L.N. Matos, Maria Cristina de Oliveira Izar, Brazil 357 287 LOW DOSE SIMVASTATIN PLUS EZETIMIBE TREATMENT REDUCE INFLAMMATORY CYTOKINES WITHOUT MODIFICATION OF HSPCR LEVELS IN HYPERCHOLESTEROLEMIC PATIENTS A. Cerda, C.M. Fajardo, E.S. Guimaraes, E.L. Dorea, M.C. Gosukuma, G.A. Pinto, Mario Hiroyuki Hirata, R.D.C. Hirata, Brazil 921 85 POSTERS TRACK 2: LIPID AND LIPOPROTEIN METABOLISM: FROM ALTERATIONS TO TREATMENTS (contd.) Poster Board No. Abstract No 288 COMPARISON OF LIPID LOWERING EFFECTS BETWEEN EZETIMIBE AND PRAVASTATIN: RESULTS FROM A PILOT CROSSOVER STUDY 1311 Noriaki Kume1,2, Japan 289 DO SERUM LIPID CHANGES WITH STATIN/EZETIMIBE DIFFER SUBSTANTIVELY BY BMI CATEGORY? AN ACT II STUDY ANALYSIS Dominik Lautsch1,2, H. Toplak, C. Saely1,4, M. Pichler, P. Brudi, Liechtenstein, Austria, USA 1639 290 EZETIMIBE AND ATORVASTATIN COADMINISTRATION VERSUS ATORVASTATIN UP-TITRATION OR SWITCHING TO ROSUVASTATIN IN PATIENTS WITH PRIMARY HYPERCHOLESTEROLEMIA AND HIGH CARDIOVASCULAR RISK Michel Farnier, M. Averna, C. Majul, D. Muller-Wieland, A. De Pellegrin, H. Giezek, R. Lee, R.S. Lowe, P. Brudi, J. Triscari, H.E. Bays, France, Italy, Argentina, Germany, Belgium, USA 1640 Lipid-lowering therapy / Miscellaneous 291 DIFFERENCES IN THE ATHEROGENIC RISK OF PATIENTS TREATED BY LIPOPROTEIN APHERESIS ACCORDING TO THEIR LDL CHOLESTEROL AND LIPOPROTEIN(A) LEVELS Ulrich Julius, M. von Dryander, S. Fischer, G. Müller, Germany 107 292 BEZAFIBRATE IMPROVES POSTPRANDIAL LIPEMIA AND POSTPRANDIAL ENDOTHELIAL DYSFUNCTION IN PATIENTS WITH METABOLIC SYNDROME Toru Miyoshi, H. Oe, Y. Ohno, K. Nakamura, H. Morita, K. Kusano, H. Ito, Japan 337 293 COLESEVELAM WITH LOW-DOSE STATIN IS ASSOCIATED WITH A FAVORABLE EFFECT ON MARKERS OF INSULIN RESISTANCE COMPARED WITH A HIGHER-DOSE STATIN M. Florentin, Evangelos N. Liberopoulos, A.A. Kei, C.V. Rizos, M.S. Elisaf, Greece 361 294 LIPOPROTEIN APHERESIS DURING THE FIRST-YEAR AFTER CABG IN PATIENTS WITH HYPERLIPIDEMIA Marat Ezhov, L. Il`ina, R. Adzhiev, O. Afanasieva, M. Safarova, E. Vlasova, I. Adamova, G. Konovalov, S. Pokrovsky, Russia 991 295 THE PPAR AGONIST TETRADECYLTHIOACETIC ACID REDUCES ATHEROSCLEROSIS PROGRESSION IN APOE-/- MICE BEYOND PLASMA LIPID LOWERING Rita Vik, M. Busnelli, C. Prolini, B. Bjørndal, S. Holm, T. Brattelid, S. Manzini, G. Banzetti, P. Aukrust, G. Chiesa, R.K. Berge, Norway, Italy 296 UNITED STATES TRENDS IN THE USE AND COST OF LIPID LOWERING MEDICATIONS FROM 2004 THROUGH 2012 L. Goldman Rosas, M. Shahbaz, S. Thiyagarajan, Randall Stafford, USA 1273 86 1038 POSTERS TRACK 2: LIPID AND LIPOPROTEIN METABOLISM: FROM ALTERATIONS TO TREATMENTS (contd.) Poster Board No. Abstract No Lipid-lowering therapy / Nicotinic acid 297 PHENOTYPIC DETERMINANTS OF LIPID RESPONSES TO TREATMENT WITH NICOTINIC ACID AND LAROPIPRANT IN HONG KONG CHINESE PATIENTS WITH DYSLIPIDAEMIAV Y.L. Yang, Miao Hu, B. Tomlinson, Hong Kong S.A.R. 738 298 EFFECT OF EXTENDED-RELEASE NIACIN/ LAROPIPRANT COMBINATION ON FASTING LIPIDS, GLUCOSE, INSULIN AND ADIPONECTIN LEVELS IN CHINESE PATIENTS WITH DYSLIPIDAEMIA Y.L. Yang, M. Hu, S. Yamashita, D. Masuda, Brian Tomlinson, Hong Kong S.A.R., Japan 746 299 NIACIN EFFICACY AND SAFETY IN APPARENTLY HEALTHY MEN WITH LIPOPROTEIN(A) EXCESS Nadezhda Artemeva, M. Safarova, M. Ezhov, O. Afanasieva, O. Dmitrieva, S. Pokrovsky, Russia 818 Lipid-lowering therapy / PCSK9 300 AFFITOPE®-BASED ANTI-PCSK9 VACCINES - AN INNOVATIVE APPROACH FOR LONG TERM CHOLESTEROL MANAGEMENT Gergana Galabova, C. Juno, W. Kirchstetter, E. Bilcikova, M. Edjlalipour, G. Winsauer, S. Brunner, F. Mattner, W. Schmidt, A. von Bonin, G. Staffler, Austria 371 301 DYNAMICS BETWEEN THE MONOCLONAL ANTIBODY SAR236553/REGN727, PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (PCSK9) AND LOW-DENSITY LIPOPROTEIN CHOLESTEROL (LDL-C) LEVELS (FUNDING: REGENERON/SANOFI) James M. McKenney, G.D. Swergold, T. DiCioccio, P. Belomestnov, C. Hanotin, A. Brunet, W.J. Sasiela, E.A. Stein, USA, France 485 302 THE EFFECTS OF SINGLE DOSE ADMINISTRATION OF RN316 (PF04950615), A HUMANIZED MONOCLONAL ANTIBODY BINDING PCSK9, IN HYPERCHOLESTEROLEMIC SUBJECTS B. Gumbiner, C. Udata, T. Joh, H. Liang, H. Wan, D. Shelton, P. Forgues, S. Billotte, J. Pons, C. Baum, Pamela D Garzone, USA 1268 303 THE EFFECTS OF MULTIPLE DOSE ADMINISTRATION OF RN316 (PF04950615), A HUMANIZED MONOCLONAL ANTIBODY BINDING PCSK9, IN HYPERCHOLESTEROLEMIC SUBJECTS B. Gumbiner, C. Udata, T. Joh, H. Liang, H. Wan, D. Shelton, P. Forgues, S. Billotte, J. Pons, C. Baum, Pamela D Garzone, USA 1270 Lipid-lowering therapy / Statins 305 ROSUVASTATIN EVALUATION PROGRAM FOR ESTABLISHING EFFICACY AND SAFETY IN INDIAN HYPERLIPIDEMIA PATIENTS ROSUVEES Navneet Wadhwa, B. Kotak, C. Shah, ROSUVEES Study Group, India 87 1016 POSTERS TRACK 2: LIPID AND LIPOPROTEIN METABOLISM: FROM ALTERATIONS TO TREATMENTS (contd.) Poster Board No. Abstract No 306 PREOPERATIVE STATIN TREATMENT IN CARDIAC SURGERY IS MORE EFFECTIVE IN PATIENTS WITH PREVIOUS ACTIVATION OF THE INFLAMMATORY SYSTEM Jose Rubio Alvarez, J.M. Martinez Comendador, J. Sierra Quiroga, E. Teijeira Fernandez, B. Adrio Nazar, Spain 21 307 EFFECT OF SIMVASTATIN/EZETIMIBE 10/10 MG VERSUS SIMVASTATIN 40 MG ON SERUM VITAMIN D LEVELS S.E. Makariou1,2, E.N. Liberopoulos, E. Moutzouri, M. Kostapanos, I. Panagopoulou, A. Challa, Moses Elisaf, Greece 26 308 ROSUVASTATIN SIGNIFICANTLY IMPROVES ARTERIAL STIFFNESS PARAMETERS BY PULSE-WAVE ANALYSIS IN HIGH RISK PATIENTS WITH ARTERIAL HYPERTENSION AND DYSLIPIDEMIA Olga N. Korneeva, O.M. Drapkina, L. Palatkina, E. Zyatenkova, N. Balachonova, V. Ivashkin, Russia 118 309 ROSUVASTATIN INFLUENCE ON CAROTID ATHEROSCLEROSIS. DADA Nataliya Gamletovna Dadamyants, F. Djalalov, Uzbekistan 237 310 EFFECTS OF ROSUVASTATIN VERSUS PROBUCOL ON LIPID ABNORMALITIES IN PATIENTS WITH CHRONIC KIDNEY DISEASE STAGE 3 AND ABOVE Gen Yasuda, K. Yatsu, S. Saka, N. Hirawa, Japan 244 311 NO PHARMACOGENETIC PRAVASTATIN EFFECT ON CARDIOVASCULAR EVENTS IN THE PROSPER/PHASE STUDY. IS PERSONALIZED MEDICINE WITH REGARD TO STATINS STILL REALISTIC? Iris Postmus1,2, S. Trompet1,2,3, A.J.M. de Craen1,2, D. Shiffman, J.J. Devlin, I. Ford, P.E. Slagboom2,6, R.G.J. Westendorp1,2, J.W. Jukema3,7,8, The Netherlands, USA, UK 283 312 LONG-TERM EFFECT OF STATIN ON FASTING BLOOD GLUCOSE LEVELS IN ASIAN HYPERCHOLESTEROLEMIC PATIENTS Chee Jeong Kim, M.-A. Kim, Republic of Korea 88 333 POSTERS TRACK 2: LIPID AND LIPOPROTEIN METABOLISM: FROM ALTERATIONS TO TREATMENTS (contd.) Poster Board No. Abstract No 313 STATIN USE IS ASSOCIATED WITH DEPRESSION IN MINORITY ETHNIC GROUPS IN UK Emily D. Williams, R. Stewart, T. Tillin, N. Chaturvedi, A.D. Hughes, UK 554 314 ROSUVASTATIN CAN REDUCE AORTIC STIFFNESS IN HYPERCHOLESTEROLEMIC PATIENTS BY FAVORABLE HEMODYNAMIC CHANGES, INDEPENDENT OF LIPID LOWERING AND ANTI-INFLAMMATORY EFFECTS P.C. Oh, Seung Hwan Han, J. Seo, K.K. Koh, T.H. Ahn, E.K. Shin, Republic of Korea 644 315 EFFECTS OF TWO DIFFERENT STATINS ON VASCULAR INFLAMMATION MARKERS IN ACUTE CORONARY SYNDROMES DURING IN-HOSPITAL FOLLOW-UP Ali Çoner, A. Aydınalp, V. Çamkıran, K. Okyay, U.A. Bal, A. Yıldırır, H. Müderrisoğlu, Turkey 708 PRAVASTATIN COMBINED WITH VALSARTAN SHOWS ADDITIVE BENEFICIAL VASCULAR EFFECTS IN PATIENTS WITH HYPERCHOLESTEROLEMIA Kwang Koh, M. Quon, Republic of Korea, USA 727 316 317 COMBINATION THERAPY WITH PRAVASTATIN AND VALSARTAN HAS ADDITIVE EFFECTS TO IMPROVE METABOLIC PHENOTYPES OVER MONOTHERAPY IN HYPERCHOLESTEROLEMIC PATIENTS Kwang Koh, M. Quon, Republic of Korea, USA 728 318 EFFECT OF ROSUVASTATIN ON ATHEROSCLEROSIS OF CAROTID ARTERIES M. Kenjaev, Azizjon Nizomov, M.B. Urinov, Uzbekistan 873 EFFICACY OF ROSUVASTATIN ON INFLAMMATORY MARKERS IN PATIENTS WITH ACUTE CORONARY SYNDROME Azizjon Abdumatlubovich Nizomov, Uzbekistan 893 319 320 ATORVASTATIN INDUCES ENDOGLIN AND ENOS EXPRESSION IN ENDOTHELIAL CELLS Lenka Zemankova, M. Varejckova, Z. Strasky, P. Nachtigal, Czech Republic1011 321 EFFECT OF PRAVASTATIN ON ATHEROSCLEROSIS IN BRAHIOCEPHALIC ARTERY IN APOE/LDL R-/- MICE FED LOW CARBOHYDRATE HIGH PROTEIN DIET Magdalena Anna Franczyk-Zarow, E. Maslak, I. Czyzynska, A. Drahun, A. Jasztal, L. Mateuszuk, S. Chlopicki, R.B. Kostogrys, Poland 1050 89 POSTERS TRACK 2: LIPID AND LIPOPROTEIN METABOLISM: FROM ALTERATIONS TO TREATMENTS (contd.) Poster Board No. Abstract No 322 PROTECTION BY L-CARNITINE OF STATIN INDUCED MUSCLE MITOCHONDRIAL DYSFUNCTION P.G. La Guardia, L.C. Alberici, F.G. Ravagnani, R.R. Catharino, Anibal E. Vercesi, Brazil 1063 323 EFFECT OF ROSUVASTATIN ON MICRORNAS EXPRESSION IN HUMAN ATHEROSCLEROTIC PLAQUES: RESULTS FROM QUASAR STUDY Pamela Marcantonio, D. Santovito, D. Mastroiacovo, C. Mandolini, V. De Nardis, G. De Blasis, A. Mezzetti, G. Desideri, F. Cipollone, Italy 1064 324 STATIN IS ASSOCIATED WITH LOWER DEEP VEIN THROMBOSIS INCIDENCE CONFIRMED BY CT ANGIOGRAPHY IN PATIENTS UNDERGOING TOTAL KNEE REPLACEMENT ARTHROPLASTY Sang-Ho Jo, H.-S. Kim, Republic of Korea 325 CUMULATIVE MORTALITY DUE TO HIGH DOSES OF ATORVASTATIN GIVEN TO HYPERCHOLESTEROLEMIC MICE Juan C. Diaz-Zagoya, I.E. Juárez-Rojop, A.E. Castell-Rodríguez, J.L. BléCastillo, R. Miranda-Zamora, Mexico 1302 326 EFFECTS OF PITAVASTATIN ON HIGH DENSITY LIPOPROTEIN CHOLESTEROL IN ELDERLY PATIENTS WITH DIABETES Hyang-Lim Lee, S.-H. Kim, D.-G. Park, Republic of Korea 1253 1494 327 ATORVASTATIN AND THE RISK TO DEVELOP DIABETES MELLITUS Renato Alves, G. Paranhos, N. Scalissi, J. Salles, Brazil 1589 328 PITAVASTATIN HAS NEUTRAL EFFECTS ON GLYCAEMIC PARAMETERS IN METABOLIC SYNDROME: THE CAPITAIN AND PREVAIL US TRIALS N. Hounslow, P. Giral, C.A. Sponseller, P. Robillard, A. Orsoni, M John Chapman, UK, France, USA 1615 329 NEUTRAL EFFECT OF PITAVASTATIN ON GLYCAEMIC PARAMETERS IN METABOLIC SYNDROME : THE CAPITAIN TRIAL M John Chapman, N. Hounslow, A. Orsoni, M. Suzuki, P. Robillard, P. Giral, France, UK 1616 330 NEW INSIGHTS INTO STATIN ACTION ON THE DYSLIPIDEMIA OF METABOLIC SYNDROME: NORMALISATION OF BIOACTIVE PLASMALOGENS AND SPHINGOLIPIDS IN HDL Peter J. Meikle, G. Wong, A.R. Tan, B.A. Kingwell, A.K. Orsoni, N. Hounslow, P. Giral, M.J. Chapman, France, UK 90 1643 POSTERS TRACK 3: RISK FACTORS, EPIDEMIOLOGY, PREVENTION, AND TREATMENT OF CARDIOVASCULAR DISEASES Poster Board No. Abstract No Cardiovascular epidemiology 331 DYNAMICS OF ATHEROSCLEROTIC LOADING OF CAROTID ARTERIES IN MOSCOW POPULATION UNDER TWO-YEAR OBSERVATION Olga Pogorelova, M. Tripoten, A. Rogoza, V. Kukharchuk, Y. Karpov, S. Boytsov, T. Balakhonova, Russia 1128 332 ESTIMATION OF CORONARY ARTERY DISEASE ACCORDING TO CARDIAC RISK FACTORS IN IRANIAN URBAN POPULATION Sepideh Sokhanvar, S.A.N. Kazemi, S.N. Mousavinasab, Iran 1358 333 LONG TERM MORTALITY FOLLOWING CAROTID ENDARTERECTOMY IS GOOD Gareth Harrison, G. Lawrence, A. Stead, C. Chan, UK 1606 334 PREVALENCE OF HEART DISEASE RISK FACTORS IN THE AZORES Rita Ferin, E. Schaefer, K. Horvath, J. Baptista, M.L. Pavão, Portugal, USA 139 335 MAJOR ADVERSE CARDIOVASCULAR EVENTS IN ADULT CONGENITAL HEART DISEASE: AN ASIA POPULATION-BASED LONGTERM STUDY Pao-Hsien Chu, Y.-S. Lin, C.-J. Chang, Taiwan R.O.C. 458 336 CAROTID ATHEROSCLEROSIS AMONG GENERAL JAPANESE WITH ESTIMATED 10-YEAR ABSOLUTE RISK OF CAD DEATH ACCORDING TO THE JAPAN ATHEROSCLEROSIS SOCIETY GUIDELINE2012 Aya Kadota, K. Miura, T. Okamura, A. Fujiyoshi, T. Ohkubo, T. Kadowaki, N. Takashima, T. Hisamatsu, Y. Nakamura, F. Kasagi, H. Maegawa, A. Kashiwagi, H. Ueshima, the SESSA Research Group and the NIPPON DATA80/90 Research Group, Japan 469 337 ASSOCIATION OF ELECTROPHYSIOLOGICAL MARKERS OF SUDDEN CARDIAC DEATH INCREASED RISK WITH LIPID METABOLISM AND INFLAMMATION BIOMARKERS IN CORONARY ATHEROSCLEROSIS Sergei Ponkin, A. Kuznetsov, Y. Ragino, A. Chernyavskiy, M. Voevoda, Russia 470 338 RISK FACTORS FOR HEART DISEASE IN MIDDLE-AGED WOMEN DRIVING CAR A.V. Petrischeva, Natalya Koryagina, Russia 563 339 THE ESTIMATED RISK OF FATAL CARDIOVASCULAR DISEASE IN ASYMPTOMATIC ROMANIAN AERONAUTICAL PERSONNEL ACCORDING TO ESC CRITERIA Mirela Anghel, Romania 614 ENDOTHELIUM FUNCTION MARKERS AT CARDIOVASCULAR DISEASES Roman Iosifovich Vorobyev, E.N. Vorobyeva, Russia 654 340 91 POSTERS TRACK 3: RISK FACTORS, EPIDEMIOLOGY, PREVENTION, AND TREATMENT OF CARDIOVASCULAR DISEASES (contd.) Poster Board No. 341 Abstract No CONTROL OF CORONARY RISK WITH USE OF THE COMPUTER PROGRAMS Roman Iosifovich Vorobyev, E.N. Vorobyeva, Russia 656 342 ESTIMATION OF THE GLOBAL CARDIOVASCULAR RISK IN THE HSHS “HAMMAM-SOUSSE SAHLOUL HEART STUDY” AND COMPARISON OF 4 FORMULAS A. Moussa, K. Rouis, Asma Omezzine, I. Boumaiza, J. Rejeb, L. Rebhi, L. Bouacida, S. Neffati, N. Ben Rejeb, A. Ben Abdelaziz, A. Bouslama, Tunisia 666 343 LIPID, HEMOSTASIS AND HEMODYNAMIC ASPECTS OF PREDICTING THE RISK OF CARDIOVASCULAR DEATH IN PATIENTS OF HIGH AND VERY HIGH RISK Mikhail A. Kachkovskii, V.V. Simerzin, O.A. Rubanenko, N. Kirichenko, Russia 669 344 CARDIOVASCULAR RISK FACTORS FOR MULTIVESSEL DISEASE Marina Fernandes, V.H. Pereira, J. Português, J. Guardado, F. CanárioAlmeida, F. Ferreira, I. Quelhas, A. Pereira, A. Lourenço, Portugal 802 CORONARY HEART DISEASE RISK FACTOR CONTROL AND TREATMENT IN REPUBLIC OF SRPSKA PATIENTS WITH KNOWN CORONARY HEART DISEASE( ROSCOPS) Dusko Vulic, D. Djekic, M. Krneta, A. Lazarevic, L. Sormaz, R. Skrbic, Bosnia-Herzegovina 822 345 346 RISK FACTORS FOR MULTIVESSELS CORONARY HEART DISEASES IN BOSNIAN POPULATION Belma Pojskic, A. Macic Dzankovic, A. Rosic, D. Mehinagic, M. Pojskic, Bosnia-Herzegovina 835 347 COMBINATION OF HEARTSCORE- AND SHAPE (SOCIETY FOR HEART ATTACK PREVENTION AND ERADICATION)-BASED ALGORITHMS IN CARDIOVASCULAR RISK ASSESSMENT Frederic Kontny, B. Selseth, T. Fjornes, U. Gisletun, A. Paus, M. Fortun, M. Hamre, G. Kjoelsnes, P. Tillander, Norway 965 348 THE CORRELATION IN PATIENTS WITH ACUTE CORONARY SYNDROMES BETWEEN HYPERTENSION, OXIDATIVE STRESS, PLATELETS HYPERACTIVITY, ENDOTHELIAL DYSFUNCTION AND PROGNOSIS Elena Bobescu1,2, A. Covaciu, D. Dobreanu, N. Aldulea, Romania 1147 INFLUENCE OF VASCULAR RISK FACTORS IN THE MEDIUM-TERM EVOLUTION OF PERCUTANEOUS REVASCULARIZATION OF CORONARY ATHEROSCLEROSIS Luisa Cabeza Letrán, R. Toro, M. Sobrino, M.C. Durán, I. Tinoco, C. Rodríguez, D. Corrales, J.M. Ibañez, A. Mangas, Spain 1306 349 92 POSTERS TRACK 3: RISK FACTORS, EPIDEMIOLOGY, PREVENTION, AND TREATMENT OF CARDIOVASCULAR DISEASES (contd.) Poster Board No. Abstract No 350 COMBINED EFFECTS OF BLOOD PRESSURE AND SERUM CHOLESTEROL LEVEL IN CARDIOVASCULAR DISEASE: AN ELDERLY TAIWANESE COHORT STUDY Kuo-Yang Wang, W.-W. Lin, W.-H. Yin, Taiwan R.O.C. 1308 351 HIGHER CARDIOVASCULAR RISK PROFILE IN PATIENTS WITH DEGENERATIVE AORTIC VALVE STENOSIS AND ASSOCIATED CORONARY ARTERY DISEASE D. Gilmanov, A. Vianello, A. Miceli, G. Bianchi, S. Bevilacqua, S. Berti, M. Glauber, Annamaria Mazzone, Italy 1598 Woman and cardiovascular risk 352 MINIMUM VALUE OF THYROID FAILURE TO STRUCTURE AND FUNCTION HEART WOMAN OF REPRODUCTIVE AGE Natalya Koryagina, A. Petrischeva, Russia 549 353 CV RISK SELF-ASSESSMENT FOR PERIMENOPAUSAL WOMEN Ljiljana Trtica Majnaric, A. Vcev, M. Zulj, Croatia 603 354 EFFECT OF DIFFERENTS COMBINED ORAL CONTRACEPTIVES IN THE VASCULAR ENDOTHELIUM Bianca Stocco, H.F. Fumagalli, F.J. Bianchini, S.A. Franceschini, C.M. Marzocchi-Machado, M.R. Torqueti, Brazil 866 355 NEGATIVELY AFFECTED ARTERY WALL LAYER DIMENSIONS IN WOMEN WITH PREVIOUS PREECLAMPSIA - AN INVESTIGATION BY NON-INVASIVE HIGH-FREQUENCY ULTRASOUND Tansim Akhter, M. Larsson, A.-K. Wikström, T. Naessen, Sweden 356 887 ISCHEMIA MODIFIED ALBUMIN IN POSTMENOPAUSAL WOMEN WITH CORONARY DISEASE IN RELATION TO NT-PROBNP AND HSCRP: A BIOMARKER OF ATHEROSCLEROSIS BURDEN? K. Kazanis, M. Dalamaga, E. Kassi, I. Vagionas, G. Jullien, Amalia Dionyssiou-Asteriou, Greece 1393 Biomarkers 357 A NOVEL ANTI-INFLAMMATORY ADIPOKINE, SECRETED FRIZZLEDRELATED PROTEIN 5, IS ASSOCIATED WITH CORONARY ARTERY DISEASE IN NON-ELDERLY POPULATION Masayuki Doi, T. Miyoshi, M. Iwamoto, M. Kajiya, K. Nosaka, K. Ohkawa, R. Nakayama, W. Takagi, K. Takeda, S. Hirohata, S. Kusachi, H. Ito, Japan 378 358 DEVELOPMENT OF A FULLY AUTOMATED LATEX ENHANCED TIA FOR ADIPONECTIN Yosuke Meguro, Y. Ito, Y. Minakawa, H. Mizue, Japan 93 408 POSTERS TRACK 3: RISK FACTORS, EPIDEMIOLOGY, PREVENTION, AND TREATMENT OF CARDIOVASCULAR DISEASES (contd.) Poster Board No. Abstract No 359 INCREMENTAL VALUE OF CIRCULATING ADIPONECTIN LEVELS IN PREDICTING THE EXTENT OF CORONARY ATHEROSCLEROSIS ASSESSED BY COMPUTED TOMOGRAPHY ANGIOGRAPHY Morihiro Matsuda, R. Tamura, O. Nishimoto, K. Kanno, T. Segawa, K. Nakamoto, H. Nishiyama, T. Kawamoto, Japan 360 A PRELIMINARY STUDY ABOUT NT-PROBNP AS A SCREENING TEST FOR HEART FAILURE IN A HEALTH CHECK Jiro Suwa, Japan 128 361 PROGNOSTIC SIGNIFICANCE OF LONG PENTRAXIN-3 LEVEL IN PATIENT WITH ACUTE CORONARY SYNDROME S. Altay, Huseyin Altug Cakmak, T. Kemaloglu, A. Turer, B. Erer, G. Can, I. Keles, M. Eren, Turkey 436 362 1 H-NMR SPECTROMETRIC IDENTIFICATION OF BIOMARKERS OF ATHEROSCLEROSIS IN THE APOLIPOPROTEIN-E KNOCKOUT MOUSE Peshang Abdulhannan1,2, S. Saha, N. Yuldasheva, S. Wheatcroft, D. 592 Russell1,3, S. Homer-Vanniasinkam1,3, J. Fisher, UK 363 CIRCULATING ANTI-BETA2-GLYCOPROTEIN-I ANTIBODIES OF PERIPHERAL ARTERIAL DISEASE PATIENTS TRIGGERS A GENOMIC OVER-EXPRESSION OF TOLL-LIKE RECEPTOR 4 IN ENDOTHELIAL CELLS Cesar Varela, J. De Haro, S. Bleda, L. Esparza, A. Ferruelo, F. Acin, Spain 681 364 THE MONITORING OF EFFECTS OF LIPOIC ACID FOCUSING ON CELL PROLIFERATION AND THE DETERMINATION OF ITS CONCENTRATION IN PLASMA Soňa Bencová, P. Žáková, K. Královec, L. Geryk, Czech Republic 735 365 THE RELATIONSHIP BETWEEN PLASMA LONG PENTRAXIN-3 LEVEL AND RENAL FUNCTIONS IN ACUTE CORONARY SYNDROME Ibrahim Keles, S. Altay, H.A. Cakmak, T. Kemaloglu, A. Turer, F.O. Karadeniz, G. Can, B. Erer, M. Eren, Turkey 783 366 TOTAL BILIRUBIN IN YOUNG MEN AND WOMEN : ASSOCIATION WITH RISK MARKERS FOR CARDIOVASCULAR DISEASES Marina Stojanov, A. Stefanovic, G. Dzingalasevic, J. Ivanisevic, M. Miljkovic, S. Mandic-Radic, M. Prostran, Serbia 1190 367 SERUM CALPROTECTIN LEVELS IN APPARENTLY HEALTHY JAPANESE SUBJECTS Yukio Ikeda, Y. Kumon, T. Ohguro, N. Hisakawa, J. Nishiuchi, S. Yamanaka, T. Sugiura, Japan 368 899 1232 FIBRONECTIN EXTRA DOMAIN-A AND CARDIOVASCULAR DISEASE: EVIDENCES FROM ANIMAL MODELS Vivek Krishna Pulakazhi Venu, R. Baetta, P. Uboldi, N. Ferri, A. Muro, A. 1254 Corsini, G.D. Norata1,3, A.L. Catapano1,4, Italy 94 POSTERS TRACK 3: RISK FACTORS, EPIDEMIOLOGY, PREVENTION, AND TREATMENT OF CARDIOVASCULAR DISEASES (contd.) Poster Board No. 369 370 Abstract No TMAO: A NEW MARKER OF ATHEROSCLEROSIS? Samira De Oliveira1,2, V. Ferchaud-Rouchet, K. Bach, Y. Goueffic, K. Ougerram1,2, M. Krempf1,2, France 1265 HAIR SELENIUM CONCENTRATION OF HYPERLIPIDEMIC PATIENTS WITH VARIOUS RISK FACTORS OF ATHEROSCLEROSIS Péter Fülöp, I. Seres, I. Juhász, Z. Jenei, G. Paragh, Hungary 1267 Functional assessment of arterial wall 371 ARTERIAL STIFFNESS IS INDEPENDENTLY ASSOCIATED WITH INHOSPITAL EARLY CLINICAL OUTCOME AFTER ISCHEMIC STROKE Christina Voulgari, E. Jude, S. Avgeri, S. Paximadas, S. Pagoni, Greece, UK 311 372 EVALUATION OF ULTRASOUND ASSESSED FLOW-MEDIATED VASODILATION IN THE GÖTTINGEN MINIPIG Trine Pagh Ludvigsen, N. Wiinberg, B.Ø. Christoffersen, S.G. Moesgaard, H.D. Pedersen, L.H. Olsen, Denmark 400 373 COLOR DOPPLER ULTRASOUND (CDUS) ANALYSIS OF TURBULENT FLOW IN THREE DIFFERENT ANIMAL MODELS J.J. Elias, K. Mata, C.R. Fernandes, Simone Gusmão Ramos, Brazil 511 374 NON-INVASIVE DETECTION OF CORONARY ARTERY DISEASE USING COMPUTERIZED ANALYSIS OF DIASTOLIC HEART SOUNDS Samuel Emil Schmidt, S. Winther, N.R. Holm, E. Toft, J.J. Struijk, M. Bøttcher, Denmark 547 375 ASSOCIATION BETWEEN PULSE WAVE VELOCITY AND CORONARY ARTERY CALCIFICATION IN A GENERAL JAPANESE MALE POPULATION: SESSA Sayuki Torii, T. Ohkubo, A. Fujiyoshi, A. Kadota, N. Takashima, S. Kadowaki, T. Hisamatsu, Y. Saitoh, N. Miyagawa, M. Zaid, Y. Murakami, K. Miura, H. Ueshima, Shiga Epidemiological Study of Subclinical Atherosclerosis (SESSA) Research Group, Japan 551 376 SOUTH ASIANS HAVE REDUCED LEFT VENTRICULAR SYSTOLIC LONGITUDINAL FUNCTION THAT IS NOT EXPLAINED BY THEIR EXCESS CARDIOVASCULAR DISEASE RISK Chloe May Park, K. March, T. Tillin, N. Chaturvedi, A.D. Hughes, UK 566 377 ABNORMAL METABOLIC PARAMETERS ARE INDEPENDENT FACTORS FOR INCREASED AORTIC STIFFNESS IN HEALTHY, NO DRUG TREATMENTS SUBJECTS Seung Hwan Han, H.S. Hwang, J. Moon, S.Y. Suh, K.H. Lee, K.K. Koh, T.H. Ahn, I.S. Choi, E.K. Shin, Republic of Korea 646 378 EVALUATION OF INTIMA MEDIA THICKNESS AND VASCULAR COMPLIANCE AT COMMON CAROTID AND FEMORAL ARTERIES IN ATHLETES AND YOUNG CONTROLS Gabriele Cioni, R. Marcucci, A.M. Gori, A. Rogolino, G.F. Gensini, R. Abbate, M. Boddi, Italy 1085 95 POSTERS TRACK 3: RISK FACTORS, EPIDEMIOLOGY, PREVENTION, AND TREATMENT OF CARDIOVASCULAR DISEASES (contd.) Poster Board No. Abstract No 379 ATTENUATED VASCULAR ENDOTHELIAL FUNCTION ASSESSED BY PERIPHERAL ARTERIAL TONOMETRY IS ASSOCIATED WITH CARDIOVASCULAR RISK FACTORS IN MIDDLE-AGED FEMALE WORKERS Jussi Konttinen, H. Lindholm, J. Sinisalo, J. Uitti, Finland 1152 380 THE CLINICAL SIGNIFICANCE OF CONDITIONS PRESENTED BY ECG CHANGES MIMICKING ACUTE MYOCARDIAL INFARCTION 1294 Malka Yahalom, N. Roguin, Y. Turgeman1,2, Israel 381 DIFFERENCES IN ARTERIAL STIFFNESS BETWEEN ISCHEMIC STROKE SUBTYPES Peter Wohlfahrt, A. Krajcoviechova, O. Mayer, J. Vanek, J. Filipovsky, R. Cifkova, Czech Republic 1335 382 ADDITIVE VALUE OF LOWER EXTREMITY ARTERIAL STIFFNESS TO AORTIC STIFFNESS FOR PREDICTING TARGET ORGAN DAMAGE Peter Wohlfahrt1,2, A. Krajcoviechova, J. Seidlerova, O. Mayer, J. Filipovsky, S. Laurent, R. Cifkova, Czech Republic, France 1339 383 REACTIVE HYPEREMIC INDEX MEASURED BY PERIPHERAL ARTERY TONOMETRY ASSOCIATES WITH RADIAL ARTERY INTIMA-MEDIATHICKNESS, PATIENTS WITH SUSPECTED CORONARY ARTERY DISEASE 1371 Charlotte Eklund, L.-M. Gan1,2, Sweden Imaging / IMTc 384 PREVALENCE AND CARDIAC RISK FACTORS PREDICTORS OF SUBCLINICAL ATHEROSCLEROSIS, INCREASED CAROTID INTIMAMEDIA THICKENING AND CARDIOVASCULAR DISEASE IN MORBID OBESITY Julio Oscar Bono, R. Chiosso, R. Del Valle, J.M. Foscarini, C. Esquivel, L. Ahuad, E. Moreyra, A. Surur, Argentina 864 385 CAROTID INTIMA MEDIA THICKNESS AS A RISK FACTOR FOR INCREASED CORONARY CALCIUM SCORE A. Bertolami, C. Gonzaga, M. Sulzbach, D.B. Araujo, H. Zatz, R. Gonçalves, A.A. Faludi, Marcelo Chiara Bertolami, Brazil 1164 386 IMAGING METHODS OF CAROTID ARTERIES STENOSIS Nataliya Dadamyants, Uzbekistan 387 1266 CA-IMT AND QT PARAMETERS IN DYSLIPIDEMIC PATIENTS IN PRIMARY PREVENTION AT DIFFERENT ESC/EAS CARDIOVASCULAR RISK LEVELS G. Mombelli, Barbara Terraneo, F. Pazzucconi, C. Pavanello, R. Bosisio, M. 1340 Triolo, V. Barbieri, P. Magni, S. Castelnuovo, C.R. Sirtori 1,2, Italy 96 POSTERS TRACK 3: RISK FACTORS, EPIDEMIOLOGY, PREVENTION, AND TREATMENT OF CARDIOVASCULAR DISEASES (contd.) Poster Board No. Abstract No Imaging / Calcifications assessment 388 PATHOGENESIS OF CALCIFIED AORTIC VALVE STENOSIS: A SPECTROSCOPIC STUDY Ioannis E. Mmamarelis, K. Pissaridi, E. Koutoulakis, V. Dritsa, C. Kotoulas, V. Mamareli, J. Anastassopoulou, Greece 61 389 THE STATE OF CALCIUM METABOLISM AND LIPID PROFILE FOR PATIENTS WITH CORONARY ARTERY DISEASE DEPENDING ON THE SMOKING STATUS Irina Grebenshchikova, S. Levashov, E. Volkova, Russia 384 390 MARKER OF CALCIFIED ATHEROSCLEROSIS AT CARDIOVASCULAR DISEASES I.G. Leschenko, V.A. Leschenko, Roman Iosifovich Vorobyev, E.N. Vorobyeva, Russia 649 391 CORONARY CALCIFICATION IS SUPERIOR TO EXERCISE TOLERANCE TESTING IN PREDICTING SIGNIFICANT CORONARY ARTERY STENOSIS IN SYMPTOMATIC PATIENTS Tarek Bengrid, R. Nicoll, A. Schmermund, M. Henein, Sweden, Germany 762 392 CORONARY CALCIFICATION CORRELATES WITH THE PRESENCE AND SEVERITY OF VALVE CALCIFICATION IN ANGINA PATIENTS WITH NO AORTIC STENOSIS George Koulaouzidis, R. Nicoll, P. Jenkins, M. Henein, Sweden, UK 765 393 SCREENING OF ASYMPTOMATIC PATIENTS WITH TYPE 2 DIABETES AND HIGH CVD-RISKS FOR SILENT CHD: BENEFIT OF CORONARY ARTERY CALCIUM SCORING Maria Karlinskaya, Y. Poteshkin, I. Glinkina, A. Zilov, S. Ternovoy, G. Melnichenko, Russia 850 394 ATHEROSCLEROTIC EVALUATION WITH WHOLE-BODY CTA (WB-CTA) IN PATIENTS WITH CV RISK FACTORS: ARE CORONARY ARTERIES AND EXTRA-CORONARY VESSELS EQUALLY INVOLVED? Fulvio Zaccagna, A. Napoli, G. Cartocci, V. Noce, F. Boni, C. Catalano, Italy877 395 IN VIVO QUANTIFICATION OF ATHEROSCLEROTIC BURDEN: CTA´S PROGNOSTIC ACCURACY IN RELATION TO TRADITIONAL CARDIOVASCULAR RISK INDEX AND 5-YEAR FOLLOW-UP Fulvio Zaccagna, A. Napoli, G. Cartocci, V. Noce, F. Boni, C. Catalano, Italy878 396 EVALUATION OF PATIENTS PRIOR TO NON CORONARY CARDIAC SURGERY BY CARDIAC CT Sara Casquero Dominguez, N. Romero Rodriguez, M. Romero Vazquianez, M. Villa Gil-Ortega, M. Fernandez Quero, A. Guisado Rasco, A. Martinez Martinez, Spain 1566 97 POSTERS TRACK 3: RISK FACTORS, EPIDEMIOLOGY, PREVENTION, AND TREATMENT OF CARDIOVASCULAR DISEASES (contd.) Poster Board No. Abstract No Imaging / Miscellaneous 397 THE ROLE OF QUANTITATIVE CORONARY ARTERIOGRAPHY IN ANALYSIS IN PROGRESSION OF CORONARY STENOSIS TO A TOTAL OCCLUSION, NEW WAY Jovica Saponjski, B. Beleslin, V. Vukcevic, Serbia 169 398 MYOCARDIAL PERFUSION IMAGING USING 99MTC-SESTAMIBI SPECT: A CARDIAC PHANTOM STUDY Mansour Almoudi, Z. Sun, Australia 206 399 QUANTIFICATION OF CORONARY VESSEL WALL ENHANCEMENT: REPRODUCIBILITY OF METHODS AND FEASIBILITY OF QUANTIFICATION IN HEALTH AND DISEASE Niharika Varma, R. Botnar, D. D'Cruz, A. Indermuehle, S. Peel, G. Greil, T. Hussain, E. Nagel, V. Puntmann, UK 890 400 ASSESSMENT OF INTEGRATED MULTIMODAL BASED NANO-IMAGING FOR EARLY DIAGNOSIS OF CAROTID ATHEROSCLEROSIS ASSOCIATED WITH NEUROLOGICAL DISORDERS Lina H. Machtoub, Austria 947 401 GEOMETRIC APPROACH IN EVALUATING ATHEROSCLEROSIS IN LEFT CORONARY ARTERY Young Ho Choi, S.-H. Suh, H.-H. Kim, Republic of Korea 402 NON-INVASIVE ASSESSMENT OF BYPASS GRAFTS AND NATIVE CORONARY VERSUS INVASIVE CORONARY ANGIOGRAPHY BY CADIAC CT Sara Casquero Dominguez, N. Romero Rodriguez, M. Romero Vazquianez, M. Fernandez Quero, A. Guisado Rasco, M. Villa Gil-Ortega, A. Martinez Martinez, Spain 1575 1474 Imaging / Vulnerability 403 CORONARY CT ANGIOGRAPHY OF CORONARY PLAQUES: AN INVESTIGATION OF INTRALUMINAL APPEARANCES AND CORRELATION OF LEFT BIFURCATION ANGULATION WITH PLAQUE FORMATION Zhonghua Sun, M. Almoudi, Australia 207 404 IMAGING VULNERABLE ATHEROSCLEROTIC PLAQUES BY TARGETING CO-STIMULATORY MOLECULES Adrienne Müller, L. Mu, K. Beck, R. Meletta, Z. Rancic, K. Drandarov, P.A. 548 Kaufmann, R. Schibli1,2, S.M. Ametamey, S.D. Krämer, Switzerland 405 MORPHOLOGICAL PLAQUE FEATURES SUGGEST CONTRALATERAL CAROTID VULNERABILITY IN SYMPTOMATIC BUT NOT ASYMPTOMATIC PATIENTS Fisnik Jashari, P. Ibrahimi, E. Johansson, C. Gronlund, G. Bajraktari, P. Wester, M. Henein, Sweden 605 98 POSTERS TRACK 3: RISK FACTORS, EPIDEMIOLOGY, PREVENTION, AND TREATMENT OF CARDIOVASCULAR DISEASES (contd.) Poster Board No. Abstract No 406 SYMPTOMATIC PATIENTS WITH CAROTID DISEASE HAVE MORE VULNERABLE CONTRALATERAL PLAQUES THAN ASYMPTOMATIC Pranvera Ibrahimi, F. Jashari, E. Johansson, C. Gronlund, G. Bajraktari, P. Wester, M. Henein, Sweden 611 407 RISK ASSESSMENT OF ATHEROSCLEROTIC PLAQUES BASED ON GLOBAL BIOMECHANICS Simone Melchionna, H.-E. Lee, G. Amati, M. Bernaschi, M. Bisson, S. Succi, Italy, Republic of Korea 408 769 EVALUATION OF [18F]-FLUORODEOXYGLUCOSE UPTAKE IN THE AORTIC ARCH OF APOLIPOPROTEIN E-DEFICIENT MICE Jakub Toczek, A. Broisat, P. Perret, D. Fagret, L.M. Riou, C. Ghezzi, France1331 Genetics 409 ASSOCIATION STUDY OF 10 GENE VARIANTS WITH ANGIOGRAPHIC SEVERITY OF CORONARY ARTERY DISEASE Martin Javorsky1,2, V. Vitanov, L. Klimcakova, V. Habalova, J. Zidzik, E. 291 Babjakova1,2, J. Salagovic, B. Stancak, I. Tkac1,2, Slovak Republic 410 POSSIBLE GENE-GNDER INTERACTION BETWEEN THE SLCO1B1 POLYMORPHISM AND STATIN TREATMENT EFFICACY Jaroslav Hubacek, D. Dlouha, V. Adamkova, V. Lanska, R. Ceska, M. Vrablik, Czech Republic 345 411 LACK OF AN ASSOCIATION BETWEEN THE MRAS POLYMORPHISM AND ACS RISK IN CZECH POPULATION Jaroslav A. Hubacek, V. Adamkova, V. Lanska, R. Ceska, M. Vrablik, R. Poledne, M. Gebauerova, V. Stanek, J. Pitha, Czech Republic 349 412 MCP1 POLYMORPHISMS ARE ASSOCIATED WITH SEVERAL CARDIOMETABOLIC PARAMETERS BUT NOT WITH PREMATURE CORONARY ARTERY DISEASE IN THE MEXICAN POPULATION Gilberto Vargas-Alarcón, T. Villarreal-Molina, R. Posadas-Sánchez, E. Alvarez-León, S. Canizales-Quinteros, E. Kimura-Hayama, S. RomeroHidalgo, J.G. Juárez-Rojas, E. Larrieta-Carrasco, V. Acuña-Alonzo, E. JorgeGalarza, C. Posadas-Romero, Mexico 525 413 ASSOCIATION BETWEEN THE A603G TISSUE FACTOR GEN POLYMORPHISM, MARKERS OF ENDOTHELIAL DYSFUNCTION AND INCIDENCE OF MYOCARDIAL INFARCTION IN RUSSIA Elena Gennadyevna Sergeeva1,2, M.A. Karpenko, Z.I. Ionova, G.V. Alekseeva, S. Saha, D. Saha, Russia 414 670 POLYMORPHISMS OF METHYLENETETRAHYDROFOLATE REDUCTASE GENE (MTHFR), HOMOCYSTEINE LEVEL, AND RISK FACTORS FOR CAD IN THAI Ingkarat Sarutipaiboon, N. Settasatian, C. Settasatian, N. Komanasin, U. Kukongwiriyapan, P. Intharapetch, K. Tantipanichteerakul, V. Senthong, Cardiovascular Research Group, Khon Kaen University, Thailand 716 99 POSTERS TRACK 3: RISK FACTORS, EPIDEMIOLOGY, PREVENTION, AND TREATMENT OF CARDIOVASCULAR DISEASES (contd.) Poster Board No. Abstract No 415 PROBABLE IMPACT OF POLYMORPHIC VARIANTS SOME HAEMOSTATIC AND FOLATE SYSTEM GENES IN THE RISK OF RESTENOSIS AFTER PERCUTANEOUS CORONARY INTERVENTION Galina Chumakova1,2, A. Dashkova1,2, A. Momot, N. Veselovskaya2,4, Russia 416 THE LEVEL OF HETEROPLASMY OF MITOCHONDRIAL GENOME IS AN EXPLANATORY BIOMARKER FOR BOTH SUBCLINICAL AND MANIFESTED ATHEROSCLEROSIS Igor A. Sobenin1,2, M.A. Sazonova1,2, M.M. Chicheva-Ivanova, K.Y. 861 Mitrofanov, A.V. Zhelankin, Y.V. Bobryshev2,3, A.N. Orekhov2,3, Russia 417 GENETIC APPROACH TO CARDIOVASCULAR DISEASE PREVENTION: POLYMORPHISMS IN CANDIDATE GENES INVOLVED IN RISK FACTORS FOR CARDIOVASCULAR DISEASE Chatri Settasatian, N. Settasatian, P. Intharapetch, P. Yongsakulchai, I. Sarutipaiboon, P. Pitivej Thurakit, K. Tantipanichteerakul, V. Senthong, Cardiovascular Research Group, Khon Kaen University, Thailand 934 418 GENETIC VARIATIONS IN PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPARS) AND THEIR RELATED GENES INFLUENCE CARDIOVASCULAR DISEASE RISK IN THAI Pratthana Yongsakulchai, C. Settasatian, N. Settasatian, N. Komanasin, U. Kukongwiriyapan, P. Intharapetch, K. Tantipanichteerakul, V. Senthong, Cardiovascular Research Group, Khon Kaen University, Thailand 956 419 THE ROLE OF +405G/C AND -2578C/A POLYMORPHISMS OF VEGF IN PERIPHERAL ARTERIAL DISEASE Ignacio López de Maturana Carrasco, S. Bleda Moreno, J. de Haro Miralles, L. Esparza Gómez, C. Varela Casariego, J. Rodriguez Padilla, F. Acín García, Spain 1129 420 PPARΓ MUTATIONS RESPONSIBLE FOR LIPODYSTROPHY WITH SEVERE HYPERTENSION ACTIVATE THE CELLULAR RENINANGIOTENSIN SYSTEM Franck Boccara1,2, M. Auclair, C. Vigouroux, E. Capel, C. Vigeral, B. Guerci, O. Lascols, J. Capeau, M. Caron-Debarle, France 1249 421 ASSOCIATION OF ADIPOQ GENE VARIANTS AND HEART FAILURE IN AN ITALIAN POPULATION Silvana Pileggi, S. Barlera, C. Casola, L. Crociati, S. Pietri, C. Specchia1,2, M.G. Franzosi, Italy 1260 422 TERC RS12696304C ALLELE AND TRF1 RS2975843C ALLELE SIGNIFICANTLY INCREASE THE RISK OF EARLY-ONSET ISCHEMIC STROKE Fang-I Hsieh, W.-Y. Lin, H.-J. Lin, L.-M. Lien3,4, C.-C. Yu, Y.-R. Chen, H.-Y. Chiou, Taiwan R.O.C. 1443 100 759 POSTERS TRACK 3: RISK FACTORS, EPIDEMIOLOGY, PREVENTION, AND TREATMENT OF CARDIOVASCULAR DISEASES (contd.) Poster Board No. Abstract No 423 OPERATIONAL REDEFINITION OF THE TISSUE ANGIOTENSIN SYSTEM FROM GENE CO-EXPRESSION IN ATHEROGENESIS Catherine Cerutti, S. Barrot, M.-P. Gustin, H. Ayari, C. Paultre, P. Feugier, L. Legedz, G. Bricca, France 1465 424 INTERACTION BETWEEN I148M IN THE ADIPONUTRIN GENE (PNPLA3) AND DIETARY INTAKES OF CARBOHYDRATES AND N-6/N-3POLYUNSATURATED FATS ON FASTING TRIGLYCERIDE LEVELS I.A. Stojkovic, U. Ericson, G. Rukh, Marju Orho-Melander, Sweden 1548 425 GENOME-WIDE ASSOCIATION STUDY IDENTIFIES THREE GENOMIC LOCI SIGNIFICANTLY ASSOCIATED WITH SERUM LEVELS OF HOMOARGININE - THE ATHEROREMO CONSORTIUM Marcus Edi Kleber1,2, I. Seppälä, S. Pilz4,5, M.M. Hoffmann, A. Tomaschitz, N. Oksala3,8, E. Raitoharju, L.-P. Lyytikäinen, K.-M. Mäkelä, R. Laaksonen, M. Kähönen, O.T. Raitakari10,11, J. Huang, C. Drechsler, V. Krane, C. Wanner, B.O. Böhm, W. König, T. Lehtimäki, W. März1,15,16, A. Meinitzer, Germany, Finland, The Netherlands, Austria 1561 426 THE AGT M235T POLYMORPHISM ASSOCIATES WITH AMI RISK AND INFLUENCES CAD SEVERITY Sounira Mehri, R. Chaaba, M. Hammami, Tunisia 1602 Obesity and fat distribution 427 EFFECT OF VARIOUS BARIATRIC SURGICAL PROCEDURES ON PLASMA APO-CIII LEVELS N. Padilla, M. Maraninchi, B. Berthet, A. Bégu-Le Corroller, N. Dubois, R. Grangeot, C. Mattei, B. Vialettes, René Valéro, France 970 428 OBESITY MODULATES THE IMMUNE RESPONSE TO OXIDIZED LDL AND INFLAMMATORY MILIEU IN HYPERTENSIVE PATIENTS H.A. Fonseca1,2, F.A. Fonseca, A.M. Monterio, H.T. Bianco, S.A. Brandão, M. Gidlund, Maria Cristina Izar, Brazil 240 429 WEIGHT LOSS INDUCED IMPROVEMENTS IN LIPIDS IN OVERWEIGHT/OBESE SUBJECTS TREATED WITH PHENTERMINE/TOPIRAMATE EXTENDED-RELEASE (PHEN/TPM ER) Hermann Toplak, S. Klein, W.W. Day, Austria, USA 391 430 BMI OR WAIST CIRCUMFERENCE - WHICH IS THE MORE RELIABLE MARKER FOR PREDICTING CARDIOVASCULAR DISEASE? Helen Marcoyannopoulou Fojas, E. Barrios, Philippines 480 431 REDUCTION OF P WAVE DISPERSION AFTER THERAPEUTIC WEIGHT LOSS IN OVERWEIGHT AND OBESE PATIENTS Anna Giulia Falchi, C. Muggia, C. Tinelli, Italy 522 432 CALORIC RESTRICTION INDUCES OBESITY AND DIABETES AND AGGRAVATES SPONTANEOUS ATHEROSCLEROSIS DEVELOPMENT IN HYPERCHOLESTEROLEMIC MICE G.G. Dorighello, J.C. Rovani, C.J.F. Luhman, B.A. Paim, A.E. Vercesi, Helena C F Oliveira, Brazil 620 101 POSTERS TRACK 3: RISK FACTORS, EPIDEMIOLOGY, PREVENTION, AND TREATMENT OF CARDIOVASCULAR DISEASES (contd.) Poster Board No. Abstract No 433 LONG TERM STATUS OF METABOLIC PARAMETERS ARE RISK FACTORS FOR ABNORMAL CORONARY ENDOTHELIAL FUNCTION IN PATIENTS WITHOUT SIGNIFICANT CAD Seung Hwan Han, J. Seo, P.C. Oh, W.J. Chung, K. Lee, S.Y. Suh, W.C. Kang, K.K. Koh, T.H. Ahn, E.K. Shin, Republic of Korea 641 434 EPICARDIAL ADIPOSITY AS A MARKER OF SUBCLINICAL CORONARY ATHEROSCLEROSIS 734 N. Veselovskaya1,2, Galina Chumakova1,3, A. Ott, Russia 435 RISK OF ATHEROSCLEROSIS AND WAIST CIRCUMFERENCE CUT-OFF POINTS IN SIBERIAN POPULATION 45-69 YEARS OLD (EPIDEMIOLOGICAL STUDY) Galina Simonova, S. Mustafina, Russia 1001 436 BENEFICIAL EFFECTS OF PPARG ACTIVATION ON LIPID METABOLISM IN LIPODYSTROPHIC BSCL2-/- MICE X. Prieur, L. Dollet, M. Takhashi, J. Capeau, B. Feve, C. Le May, P. Costet, J. Magrè, Bertrand Cariou, France 1009 437 MYELOPEROXIDASE, MATRIX METALLOPROTEASE-9 AND PARAOXONASE-1 ACTIVITY IN OVERWEIGHT HYPERLIPIDEMIC PATIENTS WITH AND WITHOUT VASCULAR COMPLICATIONS Peter Koncsos, N. Zsíros, M. Harangi, H. Lőrincz, I. Seres, G. Paragh, Hungary 1018 438 CORRELATION OF TRIGLYCERIDES AND TYPE OF FAT ACCUMULATION INVESTIGATED BY COMPUTED TOMOGRAPHY IN OBESE PATIENTS Gabor Simonyi, M. Medvegy, R.J. Bedros, Hungary 1028 439 MORBID OBESITY IS A INDEPENDENT RISK FACTOR FOR DEVELOPING SUBCLINICAL ATHEROSCLEROSIS? Julio Oscar Bono, R. Del Valle, R. Chiosso, J.M. Foscarini, C. Esquivel, L. Ahuad, E. Moreyra, Argentina 1160 440 HYPOXIA INDUCES A HIF-1ALPHA DEPENDENT SIGNALLING CASCADE TO MAKE A COMPLEX METABOLIC SWITCH IN SGBSADIPOCYTES Andreas Leiherer1,2, K. Geiger, S. Geller-Rhomberg, A. Mündlein1,2, H. Drexel1,2,3, Austria, Liechtenstein 1176 441 METABOLICALLY HEALTHY OBESE INDIVIDUALS HAVE AVERAGE SUBCLINICAL ATHEROSCLEROSIS PARAMETERS COMPARED WITH METABOLICALLY UNHEALTHY INDIVIDUALS Jordi Merino, R. Ferré, D. Pedrico, M. Llort, J.P. Lonzi, N. Plana, D. Ibarretxe, L. Masana, Spain 1319 442 ASSOCIATION BETWEEN OBESITY INDICES AND SERUM LIPIDS IN OBESE NON-DIABETIC PATIENTS A. Stępień, M. Stępień, R.N. Wlazeł, M. Paradowski, Maciej Banach, J. Rysz, Poland 1324 102 POSTERS TRACK 3: RISK FACTORS, EPIDEMIOLOGY, PREVENTION, AND TREATMENT OF CARDIOVASCULAR DISEASES (contd.) Poster Board No. Abstract No 443 SERUM PHOSPHOLIPIDS AS A MARKER OF ABDOMINAL OBESITY IN POSTMENOPAUSAL OBESE WOMEN K. Charradi1,2, A. Trimeche, F. Ben Hassine, E. Aouani1,2, M. Sakly2,5, Nebil Attia2,5, Tunisia 1458 444 RELATIONSHIP BETWEEN INTRAABDOMINAL FAT DISTRIBUTION, PLASMA BIOMARKER LEVELS AND ENDOTHELIAL FUNCTION IN HYPERCHOLESTEROLEMIC SUBJECTS Peteris Tretjakovs, G. Krievina, I. Skuja, A. Jurka, I. Stukena, G. Bahs, Latvia 445 1529 PLASMA APOLIPOPROTEIN B-48 TRANSPORT IN OBESE MEN: AN IN VIVO STABLE-ISOTOPE STUDY IN POSTPRANDIAL STATE Dick C. Chan, A.T.Y. Wong, J. Pang, G.F. Watts, P.H.R. Barrett, Australia 1633 Metabolic syndrome 446 ADIPONECTIN INHIBITS ANGIOTENSIN II-MEDIATED VASCULAR INFLAMMATION AND ACCELERATED ATHEROSCLEROSIS C.V. Stijn, J. Kim, D. Bacerra, U.J. Tietge, Rajendra K. Tangirala, USA, Netherlands Antilles 1280 447 RESISTIN, AN ADIPOCYTOKINE, PROMOTES ANGIOGENESIS AND VASCULAR PERMEABILITY Hyun-Joung Lim, H. Kim, H.-Y. Park, M.-C. Cho, Republic of Korea 1426 448 TRIGLYCERIDE IS A PREDICTOR OF DIABETES MELLITUS IRRESPECTIVE OF BMI IN AN 8-YEAR COHORT STUDY IN THE JAPANESE WORKERS Tomofumi Nishikawa, T. Okamura, A. Shima3,4, Y. Kawatsu, D. Sugiyama, A. Kadota, A. Morimoto, Y. Tatsumi4,6, A. Morino, N. Sonoda, N. Miyamatsu, Japan 743 449 ATHEROGENIC DYSLIPIDEMIA IN METABOLIC SYNDROME AS A PREDICTOR OF COMPLICATIONS AFTER CORONARY ARTERY BYPASS GRAFTING Olesya Gritsenko1,2, G. Chumakova1,2, N. Veselovskaya2,3, E. Vahromeeva1,3, Russia 748 450 ANTIOXIDATIVE FUNCTION OF HDL IN METABOLIC SYNDROME: IMPACT OF A LIFESTYLE PROGRAM Boris Hansel, A. Orsoni, S. Chantepie, R. Bittar, D. Bonnefont-Rousselot, P. Giral, E. Bruckert, M.J. Chapman, A. Kontush, France 1407 451 ASSOCIATION OF LIPOPROTEIN SUBCLASS DISTRIBUTION WITH METABOLIC RISK FACTORS IN JAPANESE MEN Ryotaro Takahashi, K. Okumura, N. Taguchi, M. Suzuki, N. Ikeda, T. Murohara, Japan 452 1604 EFFECTCS OF DERANGED GLUCOSE HOMEOSTASIS ON ARTERIAL STIFFNESS IN PATIENTS WITH PRE-DIABETES MELLITUS Chang-Hua Chou, J.-Y. Chen2,3, M.-C. Wang, C.-S. Ho, W.-C. Tsai, Taiwan R.O.C. 13 103 POSTERS TRACK 3: RISK FACTORS, EPIDEMIOLOGY, PREVENTION, AND TREATMENT OF CARDIOVASCULAR DISEASES (contd.) Poster Board No. Abstract No 453 THE EFFECT OF 25(OH)VITD ADMINISTRATION ON URINE 8ISOPROSTANE LEVELS IN PATIENTS WITH METABOLIC SYNDROME S.E. Makariou1,2, E.N. Liberopoulos, A. Challa, K. Tellis, A. Tselepis, Moses Elisaf, Greece 25 454 THE EFFECT OF MOLYBDENO-ENZYMES ON ATHEROSCLEROTIC HYPERURICAEMIC PATIENTS Ioannis E. Mamarelis, K. Pissaridi, E. Koutoulakis, V. Dritsa, C. Kotoulas, V. Mamareli, J. Anastassopoulou, Greece 62 455 RELATIONSHIP ENDOTHELIAL DYSFUNCTION-CHRONOBIOLOGY TO OVERWEIGHT AND OBESE PATIENTS Teodora Gabriela Alexescu, A.V. Sitar-Taut, A. Cozma, O. Mislea, V. Negrean, M. Motocu, Romania 163 456 IMBALANCE BETWEEN ENDOTHELIAL DAMAGE AND REPAIR IN CHILDHOOD OBESITY: USE OF NOVEL BIOMARKERS Luc Bruyndonckx1,2,3, H. Franckx, E. Basslé, S. van Ierssel1,2, A. Van Craenenbroeck1,2, E. Van Craenenbroeck1,2,5, V. Hoymans1,2, C. Vrints1,2,5, D. 184 Vissers, J. Ramet, V. Conraads1,2,5, Belgium 457 METABOLIC SYNDROME AND SEVERITY OF CORONARY ARTERY DISEASE IN WEST OF IRAN Shila Berenjy, Iran 278 458 DECREASED HIGH DENSITY LIPOPROTEIN-INDUCED NO SYNTHESIS IN TYPE 2 DIABETES, TYPE 1 DIABETES AND OBESITY Laurence Duvillard1,2, S. Monier, L. Perségol, I. Robin, M.-C. Brindisi2,3, J.346 M. Petit2,3, B. Vergès2,3, France 459 THE IMPAIRED GLUCOSE REGULATION IN NON-DIABETIC SUBJECTS IN SECONDARY PREVENTION OF CARDIOVASCULAR EVENT Fouzia Kessal, R. Guermaz, A. Mammeri, A. Hatri, S. Taharboucht, S. Zekri, M. Brouri, Algeria 376 460 ASSOCIATION BETWEEN PLASMA LEPTIN CONCENTRATIONS AND DYSLIPIDEMIA IN OBESITY WITH AND WITHOUT METABOLIC SYNDROME IN A TUNISIAN POPULATION Fadoua Gannar, F. Marzougui, L. Khanfir, M. Sakly, N. Attia, Tunisia 424 461 PREVALENCE OF METABOLIC SYNDROME IN HAMMAM-SOUSSE SAHLOUL HEART STUDY ACCORDING THREE DEFINITIONS I. Boumaiza, Asma Omezzine, M. Romdhane, J. Rejeb, L. Rebhi, L. Bouacida, S. Neffati, N. Ben Rejeb, A. Ben Abdelaziz, A. Bouslama, Tunisia 495 462 THE CHANGES IN VARIOUS HYDROXYPROLINE FRACTIONS IN AORTIC TISSUE OF RABBITS ARE CLOSELY RELATED TO THE PROGRESSION OF ATHEROSCLEROSIS Mohamed Anwar K. Abdelhalim, M.M. Ghannam, Saudi Arabia 104 742 POSTERS TRACK 3: RISK FACTORS, EPIDEMIOLOGY, PREVENTION, AND TREATMENT OF CARDIOVASCULAR DISEASES (contd.) Poster Board No. Abstract No 463 CARBOHYDRATE AND METABOLIC ABNORMALITIES IN ADULT SURVIVORS OF YOUTH BRAIN TUMORS Tatyana Y. Tselovalnikova, E.E. Gybernatorova, M.G. Pavlova, A.V. Zilov, N.A. Mazerkina, A.V. Moshkin, Russia 862 464 INFLUENCE OF METABOLIC SYNDROME IN CRITICAL PATIENT MORBIDITY Jerusalen Villegas del Ojo, Spain 465 IMPACT OF OCCUPATIONAL FACTORS ON METABOLIC SYNDROME. A PREVENTIVE STRATEGY FOR PRACTITIONERS? Yolande Esquirol, V. Bongard, J.B. Ruidavets, J. Ferrieres, France 1285 466 THE RENAL RISK IN NON-DIABETIC SUBJECTS WITH METABOLIC SYNDROM Fouzia Kessal, R. Guermaz, S. Taharboucht, A. Hatri, F. Hamrour, N. Teffahi, S. Zekri, M. Brouri, Algeria 467 1193 1406 THE ACCUMULATION OF RISK FACTORS OF METABOLIC SYNDROME IS ASSOCIATED WITH THE INCREASE IN ARTERIAL STIFFNESS AMONG MIDDLE-AGED FINNISH MALES Janne Halonen, H. Lindholm, H. Sistonen, H. Gylling, Finland 1498 NASH and related disorders 468 CORRELATION OF HEPATIC ELASTICITY AND ARTERIAL STIFNESS IN SUBJECTS WITH NORMAL BODY WEIGHT, OBESITY OR TYPE 2 DIABETES Marinos Fysekidis, E. Cosson, Y. Jaber, E. Ngallhy, K. Ben Belkacem, D. Roulot, C. Pillegand, S. Chiheb, I. Banu, P. Valensi, France 1149 469 HIGHER LEVELS OF WITHIN-NORMAL-LIMITS LIVER ENZYMES AND THE PREVALENCE OF THE METABOLIC SYNDROME Itzhak Shapira, A. Steinvil, O. Kliuk Ben-Bassat, M. Cohen, S. Berliner, O. Rogowski, Israel 77 470 CONTROL OF HEPATIC GLUCONEOGENESIS THROUGH THE TUMOR SUPPRESSOR P16INK4A Sarah Hannou1,2,3, K. Bantubungi-Blum1,2,3, S. Caron-Houde1,2,3, E. Vallez1,2,3, A. Lucas1,2,3, K. Wouters1,2,3, B. Staels1,2,3, A. Tailleux1,2,3, R. 192 Paumelle1,2,3, Diabetes, France 471 OBESE HUMAN SERUM STIMULATES APOLIPOPROTEIN B OVERPRODUCTION BY HUMAN HEPATOCYTES Shirya Rashid, P. Power, M. Melone, Canada 472 EFFECTS OF TUMOR-BEARING ON SERUM AND LIVER LIPID LEVELS IN SATO LUNG CARCINOMA (SLC)-IMPLANTED RATS Masashi Kawasaki, Japan 212 105 197 POSTERS TRACK 3: RISK FACTORS, EPIDEMIOLOGY, PREVENTION, AND TREATMENT OF CARDIOVASCULAR DISEASES (contd.) Poster Board No. Abstract No 473 REDUCED EXPRESSION OF INTRACELLULAR LIPID TRANSPORTERS ASSOCIATES WITH DYSLIPIDAEMIA AND STEATOSIS IN A RODENT MODEL OF GENETIC OBESITY Ugo Soffientini, S. Dolan, A. Graham, UK 430 474 ASSOCIATION OF NEUROMEDIN U WITH LIPID METABOLISM Mika Hori, T. Mizuno, M. Harada-Shiba, Japan 540 475 SIGNIFICANT WEIGHT GAIN IN MICE EXPOSED TO THE POLLUTANT BENZO[A]PYRENE IS ASSOCIATED WITH CHANGES IN HEPATIC LIPOPROTEIN METABOLISM Hamed Layeghkhavidaki1,2, M.-C. Lanhers, S. Akbar, N. Grova, B. Appenzeller, C. Feidt, C. Corbier, F.T. Yen, France, Luxembourg 635 476 NICOTINIC ACID AMELIORATES DYSLIPIDEMIA AND PREVENTS STEATOHEPATITIS IN MONOSODIUM GLUTAMATE-TREATED OBESE MICE Masumi Hara, M. Kurano, K. Tsuneyama, K. Kikuchi, A. Takai, T. Matsushima, N. Ishizaka, K. Tsukamoto, Japan 680 477 ENDOTHELIAL DYSFUNCTION, INSULIN RESISTANCE AND OBESITY IN MICE MODELS OF NAFLD Edyta Maślak, A. Jasztal, B. Sitek, B. Proniewski, M. Sternak, A. 1071 Fedorowicz, T. Skórka, K. Jasiński, S. Chłopicki1,3, Poland 478 LIVER MARKERS AND METABOLIC SYNDROME-RELATED FACTORS OVER 5 YEARS IN THE STANISLAS STUDY Ndeye Coumba Ndiaye, B. Herbeth, G. Siest, S. Visvikis-Siest, France 1321 479 IS HOMOCYSTEINE ( HCY) A NEW MARKER OF THE CARDIOVASCULAR RISK OF NON-ALCOHOLIC STEATOHEPATITIS(NASH)? Nicoleta Valentina Leach, M. Dronca, R. Tarau, R. Rusu, T. Alexescu, Romania 1592 480 CARDIOVASCULAR RISK FACTORS IN PATIENTS WITH ASYMPTOMATIC NAFL Ilze Skuja, I. Stukena, G. Krievina, A. Lejnieks, Latvia 1597 Sub inflammatory states 481 482 SUBCLINICAL HEART INVOLVEMENT IN PATIENTS WITH SYSTEMIC SCLEROSIS Charalampos Papagoras, K. Achenbach, N. Tsifetaki, S. Tsiouris, A. Fotopoulos, A.A. Drosos, Greece 218 PROGRESSION OF SUBCLINICAL ATHEROSCLEROSIS OVER FIVE YEARS IN PATIENTS WITH EARLY RHEUMATOID ARTHRITIS Anna Södergren, K. Karp, E. Lundström, T. Smedby, B. Möller, S. Rantapää-Dahlqvist, S. Wållberg-Jonsson, Sweden 232 106 POSTERS TRACK 3: RISK FACTORS, EPIDEMIOLOGY, PREVENTION, AND TREATMENT OF CARDIOVASCULAR DISEASES (contd.) Poster Board No. 483 Abstract No VASCULAR INFLAMMATION MARKERS IN MEDIUM AND HIGH RISK ACUTE CORONARY SYNDROMES Ali Çoner, A. Aydınalp, K. Okyay, E. Özçalık, U.A. Bal, A. Yıldırır, H. Müderrisoğlu, Turkey 347 484 POSSIBILITIES OF ENDOTELIAL DYSFUNCTION ASSESSMENT AT WOMEN WITH RHEUMATOID ARTHRITIS BY DOPPLER LASER FLUOMETRIA Dmitrij Bublikov, E. Vorobjova, A. Andrienko, V. Lychov, O. Lapshataeva, Russia 389 485 WHETHER WE CAN USE SCALE SCORE IN POPULATION OF PATIENTS WITH RHEUMATOID ARTHRITIS Dmitrij Bublikov, E. Vorobjova, A. Andrienko, V. Lychov, R. Vorobjov, Russia 390 486 ORANGE JUICE AND HESPERIDIN CONSUMPTION ALTER LEUKOCYTE GENE EXPRESSION TO AN ANTI-INFLAMMATORY AND ANTI-ATHEROGENIC PROFILE IN HEALTHY VOLUNTEERS Dragan Milenkovic, C. Dubray, A. Mazur, C. Morand, France 440 487 LIPID PROFILE AND INFLAMMATORY RESPONSE IN PATIENTS WITH UNSTABLE ANGINA AFTER CORONARY STENTING: A PROSPECTIVE STUDY Natalia Musikhina, T. Petelina, L. Gapon, N. Dementjeva, V. Kuznetsov, A. Takkand, Russia 539 488 CHRONIC INFLAMMATORY RHEUMATIC DISEASE INCREASES THE RISK OF ARTERIOSCLEROSIS: CLINICAL-ULTRASOUND STUDY Olga Malysheva, H. Barghan, K. Mühlberg, C. Klein, C. Baerwald, Germany675 489 HIGH SENSITIVITY C-REACTIVE PROTEIN LEVELS ARE ASSOCIATED WITH TOTAL CORONARY ARTERY OCCLUSIONS Gustavs Latkovskis1,2,3, M. Zabunova1,2, M. Berzina, D. Juhnevica, I. 750 Urtane, L. Zarakauska, A. Erglis1,2,3, Latvia 490 THE CORRELATION BETWEEN INFLAMMATORY SYNDROME AND PRECLINICAL ATHEROSCLEROSIS IN OBESE PATIENTS Vasile Negrean, I. Cheta, O. Mislea, T. Alexescu, Romania 855 491 IDENTIFICATION OF ESSENTIAL SIGNALING PATHWAYS IN SAAINDUCED MCP-1 PRODUCTION IN VASCULAR SMOOTH MUSCLE CELLS Nicole Prüfer, M. Schuchardt, T. Huang, J. Prüfer, M. Tölle, W. Zidek, M. van der Giet, Germany 1044 492 TEMPORAL EVOLUTION OF INFLAMMATORY MARKERS AFTER BARE METAL STENT OR DRUG-ELUTING STENT IMPLANTATION A. Imaeva, S. Minelli, N. Cosentino, E. Falcioni, R. Antonazzo Panico, D. Schiavino, G. Niccoli, F. Crea, Giorgia Copponi, Russia, Italy 1182 107 POSTERS TRACK 3: RISK FACTORS, EPIDEMIOLOGY, PREVENTION, AND TREATMENT OF CARDIOVASCULAR DISEASES (contd.) Poster Board No. Abstract No 493 DIFFERENT PATTERN OF ACUTE SYSTEMIC INFLAMMATORY RESPONSE IN YOUNG AND ELDERLY STEMI PATIENTS UNDERGOING PRIMARY PCI Annamaria Mazzone, N. Botto, U. Paradossi, E. Galli, A.R. De Caterina, C. Palmieri, A. Clerico, S. Berti, A. Taddei, Italy 1245 494 INFLAMMATORY BIOMARKERS IN PATIENTS WITH TIA: CLINICAL FEATURES AND STROKE RISK FOR PATIENTS WITH DIFFERENT TIA SUBTYPES 1496 Olena Y. Fartushna1,2, Ukraine, UK Diabetes macroangiopathy / Dyslipidaemia 495 LIPID PROFILE, GLUCOSE LEVEL AND WHITE BLOOD CELL SUBTYPES IN TYPE 2 DIABETES MELLITUS PATIENTS Nongnuch Settasatian, P. Singparu, C. Sumrit, C. Settasatian, Y. Teerajetgul, P. Sanyanusin, Cardiovascular Research Group, Khon Kaen University, Thailand 729 496 DIFFERENT PATTERN OF ATHEROGENIC DYSLIPIDAEMIA AMONG NEWLY DIAGNOSED, UNTREATED PATIENTS WITH TYPE 2 DIABETES MELLITUS Andrej Dukat, P. Sabaka, L. Fabryova, J. Gajdosik, M. Zelina, S. Oravec, Slovak Republic 846 497 POTENTIAL ROLE OF MITOCHONDRIAL DYSFUNCTION IN DIABETIC HYPERTRIGLYCERIDEMIA Sampath Parthasarathy, P. Mordhwaj, D. Litvinov, USA 1144 498 THE HYPOLIPIDEMIC EFFICACIES OF AN ESSENTIAL PHOSPHOLIPIDS WITH METHIONINE AND ATORVASTATIN IN HYPERLIPIDEMIC PATIENTS WITH TYPE 2 DIABETES MELLITUS Marina Gennadievna Bubnova, D.M. Aronov, Russia 1367 499 DEFECTIVE HDL PARTICLES IN TYPE 2 DIABETES EXHIBIT AN ALTERED LIPIDOME L. Gomez Rosso1,2, M. Lhomme, T. Meroño, L. Camont, A. Dellepiane, P. Robillard, S. Chantepie, A. Zerrad, F. Brites, J.M. Chapman, Anatol Kontush, France, Argentina 1492 Diabetes macroangiopathy / Treatment 500 501 DECREASED CRP LEVELS IN RESPONSE TO A SIX-WEEK, ONCEDAILY ORAL INSULIN REGIMEN R. Eldor, Miriam Kidron, Y. Miteva, E. Arbit, Israel, Switzerland EFFECT OF DIPEPTIDLY PEPTIDASE-4 INHIBITOR TREATMENT ON LEFT VENTRICULAR STIFFNESS BY TISSUE DOPPLER IMAGING IN PATIENTS WITH TYPE 2 DIABETES Hideto Sako, S. Miura, S. Furuyama, A. Matsunaga, K. Saku, Japan 108 47 178 POSTERS TRACK 3: RISK FACTORS, EPIDEMIOLOGY, PREVENTION, AND TREATMENT OF CARDIOVASCULAR DISEASES (contd.) Poster Board No. 502 Abstract No EFFECT OF SITAGLIPTIN ON ENDOTHELIAL CELL FUNCTION IN ISCHEMIC HEART DISEASE PATIENTS WITH DIABETES MELLITUS Hitoshi Adachi, H. Takamatsu, J. Tomono, S. Oshima, Japan 401 503 INSULIN-SENSITIZING EFFECTS OF EMBELIA RIBES EXTRACT IN HIGH FAT DIET- AND LOW DOSE STREPTOZOTOCIN-INDUCED TYPE 2 DIABETES IN WISTAR RATS Uma Bhandari, H.S. Chaudhari, India 476 504 TREATMENT OF LINAGLIPTIN CAN ATTENUATE POSTPRANDIAL HYPERLIPIDEMIA Daisaku Masuda, T. Kobayashi, T. Okada, H. Nakaoka, R. Kawase, K. Nakatani, T. Ohama1,2, M. Nishida1,2, A. Matsuyama, I. Komuro, S. Yamashita, Japan 505 LAPAROSCOPIC SLEEVE GASTRECTOMY AND ROUX-EN-Y GASTRIC BYPASS ARE EQUALLY EFFECTIVE IN CORRECTING INSULIN RESISTANCE AND DIABETES D. Benaiges, J.A. Flores Le-Roux, J.J. Chillarón, M. Renard, A. Parri, J.M. Ramón, M. Pera, Juan Pedro-Botet, Spain 840 506 FROM THE GUIDES TO CLINICAL PRACTICE: PERCUTANEOUS REVASCULARIZATION IN THE DIABETIC POPULATION WITH CORONARY ATHEROSCLEROSIS Rocío Toro, M. Sobrino, L. Cabeza Letrán, C. Rodriguez, M.C. Durán, N. Caro, I. Tinoco, E. Segura, A. Mangas, Spain 1307 507 ALOGLIPTIN REDUCES LOW-DENSITY LIPOPROTEIN CHOLESTEROL IN PATIENTS TAKING STATINS Takayoshi Nemoto, K. Kashiwase, Y. Ueda, Japan 1420 752 Diabetes macroangiopathy / Miscellaneous 508 USE OF ALPHALIPOIC ACID IN PREVENTION OF CONTRAST INDUCED NEPHROPATHY IN DIABETIC PATIENTS M. Cicek, A. Yildirir, Kaan Okyay, A.C. Yazici, A. Aydinalp, S. Kanyilmaz, H. Muderrisoglu, Turkey 1552 509 CARDIO-ANKLE VASCULAR INDEX MIGHT REFLECT ENDOTHELIAL FUNCTION IN TYPE 2 DIABETES Kei Endo, A. Saiki, T. Yamaguchi, N. Kon, H. Imamura, H. Kawana, N. Ban, A. Nagumo, D. Nagayama, M. Ohira, K. Shirai, I. Tatsuno, Japan 243 510 IMPAIRED ANTIOXIDANT ACTION OF HIGH DENSITY LIPOPROTEIN FROM TYPE 1 DIABETIC PATIENTS WITH NORMOALBUMINURIA AND MICROALBUMINURIA E. Sampaio, D.S. Barbosa, T.L. Mazzuco, V.S. Nunes, M. Passarelli, E. Nakandakare, Alexandre Carrilho, Brazil 317 109 POSTERS TRACK 3: RISK FACTORS, EPIDEMIOLOGY, PREVENTION, AND TREATMENT OF CARDIOVASCULAR DISEASES (contd.) Poster Board No. Abstract No 511 NO IMPAIRED ENDOTHELIAL FUNCTION IN PATIENTS WITH DIABETES MELLITUS ACCORDING TO A POPULATION-BASED PROPENSITY SCORE MATCHING ANALYSIS K. Empen, Roberto Lorbeer, H. Völzke, T. Reffelmann, S. Schipf, M. Nauck, W. Kerner, H. Wallaschofski, S.B. Felix, M. Dörr, Germany 348 512 IS DIABETIC RETINOPATHY AN INDICATOR FOR PROGRESSIVE ATHEROSCLEROSIS: INSIGHTS FROM A 5-YEAR OBSERVATIONAL STUDY Ayman El-Menyar, H. Al-Thani, A. Hussein, A. Sadek, A. Sharaf, V. Koshy, Qatar 732 513 ICAM AND SELECTIN RECEPTOR EXPRESSION ON MONOCYTES IN PATIENTS WITH CARDIOVASCULAR DISEASE AND DIABETIC NEPHROPATHY Ivan Topchii, P. Semenovykh, V. Galchinskaya, N. Yefimova, Ukraine 744 514 EARLY DIAGNOSIS OF COMPLICATED ATHEROSCLEROTIC PLAQUES IN TYPE 2 DIABETES MELLITUS-BIOMARKERS AND IMAGING Oana Vittos, B. Toana, F. Halici, D. Marta, A. Vittos, E. Moldoveanu, Romania 753 515 SYNERGIC EFFECTS OF DIABETES AND HYPERTENSION IN THE INCREASE OF PULSE WAVE VELOCITY OVER POSTER BOARD NO. Paolo Meani, F. Cesana, C. Colombo, A. Fallanca, M. Stucchi, M. Baroni, F. Soriano, C. Giannattasio, Italy 768 516 ATHEROSCLEROTIC PLAQUES IN SUBJECTS WITH DIABETES BECOME SYMPTOMATIC AT A LOWER LEVEL OF INFLAMMATION Andreas Edsfeldt, I. Goncalves1,2, H. Grufman1,2, M. Nitulescu, A. Persson1,2, M. Nilsson1,2, C. Prehn, J. Adamski3,4,5, J. Nilsson, Sweden, Germany 517 ROLE OF A1C IN THE POSTPARTUM SCREENING OF WOMEN WITH GESTATIONAL DIABETES D. Benaiges, J.J. Chillarón, J.A. Flores Le-Roux, A. Mas, J. Puig de Dou, E. Segarra, M.J. Carrera, A. Goday, Juan Pedro-Botet, Spain 834 518 BIOCHEMICAL MARKERS OF INFLAMMATION AND ATHEROSCLEROSIS IN PATIENTS WITH STABLE ANGINA AND DIABETES MELLITUS OF TYPE 2 Tatiana Petelina, N. Musikhina, L. Gapon, N. Dementjeva, V. Kuznetsov, N. Galeeva, N. Lystsova, T. Petrashevskaya, Russia 931 519 EFFECTS OF BODY WEIGHT REDUCTION ON BODY FAT AND PLASMA LEPTIN IN OBESE PATIENTS WITH TYPE 1 DIABETES MELLITUS Frantisek Musil, V. Blaha, A. Ticha, R. Hyspler, M. Haluzik, J. Lesna, A. Smahelova, L. Sobotka, Czech Republic 971 520 ACUTE HEMODYNAMIC MODIFICATIONS AFTER A COLD PRESSURE TEST IN HEALTHY SUBJECTS AND IN TYPE 2 DIABETIC PATIENTS Marinos Fysekidis, K. Takbou, Y. Jaber, M.T. Nguyen, E. Cosson, P. Valensi, France 1246 110 824 POSTERS TRACK 3: RISK FACTORS, EPIDEMIOLOGY, PREVENTION, AND TREATMENT OF CARDIOVASCULAR DISEASES (contd.) Poster Board No. Abstract No 521 CLINICAL IMPACT OF FOLLOW-UP GLYCOSYLATED HEMOGLOBIN ON CARDIOVASCULAR OUTCOMES IN DIABETIC PATIENTS WITH STSEGMENT ELEVATION MYOCARDIAL INFARCTION AFTER SUCCESSFUL REVASCULARIZATION J. Ahn, Taek Jong Hong, H.W. Lee, J.-H. Oh, J.H. Choi, H.C. Lee, K.S. Cha, the Korea Working Group on Myocardial Infarction Investigators, Republic of Korea 1320 522 PREDICTIVE VALUE OF GLYCOSYLATED HEMOGLOBIN ON CARDIOVASCULAR OUTCOMES IN PREDIABETIC PATIENTS WITH STSEGMENT ELEVATION MYOCARDIAL INFARCTION UNDERGOING PERCUTANEOUS CORONARY INTERVENTION J. Ahn, Taek Jong Hong, H.W. Lee, J.-H. Oh, J.H. Choi, H.C. Lee, K.S. Cha, the Korea Working Group on Myocardial Infarction Investigators, Republic of Korea 1346 523 EXERCISE CAPACITY & HEART RATE VARIABILITY IN HEART FAILURE WITH DIABETES MELLITUS Teresita Corvera-Tindel1,2, L.V. Doering, F. Mody, USA 1429 Nephropathy 524 PROBUCOL SUPPRESSES INITIATION OF CHRONIC HEMODIALYSIS THERAPY AND RENAL DYSFUNCTION-RELATED DEATH IN DIABETIC NEPHROPATHY PATIENTS: SAKURA STUDY Kei Endo, A. Saiki, T. Yamaguchi, K. Sakuma, H. Sasaki, H. Imamura, Y. Sato, D. Nagayama, N. Ban, H. Kawana, A. Nagumo, M. Ohira, T. Murano, S. Yamamura, K. Shirai, I. Tatsuno, Japan 239 525 HYPERHOMOCYSTEINEMIA AND THE PRESENCE OF CVD ARE ASSOCIATED WITH KYNURENIC ACID LEVELS AND CAROTID ATHEROSCLEROSIS IN PATIENTS UNDERGOING PERITONEAL DIALYSIS Dariusz Pawlak, M. Mysliwiec, K. Pawlak, Poland 479 526 A HIGHER SERUM ARSENIC LEVEL IS ASSOCIATED WITH A HIGHER RISK FOR INCIDENT MYOCARDIAL INFARCTION IN HEMODIALYSIS PATIENTS Masaki Ohsawa, K. Tanno, K. Kato, Y. Fujishima, K. Itai, A. Okayama, T. Onoda, K. Sakata, T. Fujioka, The KAREN Study, Japan 534 527 BIOCHEMICAL DISORDERS IN MILD CHRONIC RENAL IMPAIRMENT A MODEL BUILDING APPROACH Ljiljana Majnaric, A. Vcev, Croatia 624 528 CARDIOVASCULAR DISEASE RISK AND EVENTS IN HYPERTENSIVE PATIENTS WITH CKD IN A RETROSPECTIVE COHORT IN A PRIMARY CARE SETTING 944 Yook Chin Chia1,2, S.M. Ching, Malaysia, Australia 111 POSTERS TRACK 3: RISK FACTORS, EPIDEMIOLOGY, PREVENTION, AND TREATMENT OF CARDIOVASCULAR DISEASES (contd.) Poster Board No. Abstract No 529 CONTROL OF CARDIOVASCULAR DISEASE RISK FACTORS AMONG HYPERTENSIVE PATIENTS WITH OR WITHOUT CHRONIC KIDNEY DISEASE IN PRIMARY CARE SETTING 1034 SiewMooi Ching, Y.C. Chia2,3, Malaysia, Australia 530 THE ENDOTHELIAL PROTECTIVE EFFECTS OF HIGH DENSITY LIPOPROTEIN IS DIMINISHED USING HDL FROM PATIENTS WITH CHRONIC RENAL FAILURE Mirjam Schuchardt, N. Prüfer, S. Chebli, S. Schmid, L. Klöckl, M. Tölle, W. Zidek, M. van der Giet, Germany 1045 531 THE 9P21 ALLELE AND CHRONIC ALLOGRAFT NEPHROPATHY Jan Kvasnicka, J. Hajkova, Z. Krska, O. Viklicky, T. Kvasnicka, P. Bobcikova, Czech Republic 1166 532 THE CLOPIDOGREL HYPO-RESPONSIVENESS RATE IN CHRONIC KIDNEY DISEASE SUBJECTS Ping-Yen Liu, L.-J. Hsu, Taiwan R.O.C. 1198 533 URINE ALBUMIN CREATININE RATIO COULD PREDICT CORONARY HEART DISEASE RISK IN REAL WORLD KOREAN POPULATIONS Seung Pyo Hong, Y.W. Park, S.W. Jeon, K.R. Bae, Y.S. Lee, J.B. Lee, J.K. Ryu, J.Y. Choi, K.S. Kim, S.G. Chang, Republic of Korea 1222 534 LOW HDL CHOLESTEROL IS AN INDEPENDENT PREDICTOR OF CHRONIC KIDNEY DISEASE PROGRESSION Andrea Baragetti1,2, G.D. Norata1,2, C. Sarcina, F. Rastelli, L. Grigore, F. Pellegatta, K. Garlaschelli, P. Uboldi, I. Baragetti, C. Pozzi, A.L. Catapano 1,4, Italy 1434 535 ANDROID/GYNOID RATIO IS A MARKER OF VISCERAL ADIPOSITY IN CHRONIC KIDNEY DISEASE Andrea Baragetti1,2, K. Garlaschelli, C. Sarcina, L. Grigore, F. Pellegatta, C. 1437 Tidone, G.D. Norata1,2, I. Baragetti, C. Pozzi, A.L. Catapano1,4, Italy 536 PROGRESS OF STENOSIS IN ARTERIOVENOUS GRAFT FOR HEMODIALYSIS Young Ho Choi, H.-H. Kim, S.-H. Suh, Republic of Korea 1478 Thrombosis 537 ARTEFACTUAL ELEVATION OF PLASMA SOLUBLE CD40 LIGAND BY RESIDUAL PLATELETS IN CARDIOVASCULAR DISEASE Regent Lee, A.S. Antonopoulos, Z. Alexopoulou, M. Margaritis, R.K. Kharbanda, R.P. Choudhury, C. Antoniades, K.M. Channon, UK 133 538 MEAN PLATELET VOLUME DECREASES AFTER EXTRACORPOREAL LDL-CHOLESTEROL ELIMINATION M. Blaha, M. Kostal, Vladimir Blaha, M. Lanska, S. Filip, P. Zak, Czech Republic 112 88 POSTERS TRACK 3: RISK FACTORS, EPIDEMIOLOGY, PREVENTION, AND TREATMENT OF CARDIOVASCULAR DISEASES (contd.) Poster Board No. 539 540 Abstract No VARYING EFFECTS OF DIFFERENT TYPES OF HEMODYNAMIC FORCES ON TISSUE FACTOR (TF) EXPRESSION IN ENDOTHELIAL CELLS (EC) Bauer Sumpio, USA 226 PARTICIPATION OF THROMBOXANE A2 IN SEROTONIN AND BRADYKININ EFFECTS ON RAT COMMON CAROTID AND FEMORAL ARTERY Marko Stojanović, M. Radenković, N. Skorupan, M. Prostran, Serbia 387 541 MACROPHAGES AND PLATELETS ARE THE MAJOR SOURCE OF THE FACTOR SEVEN ACTIVATING PROTEASE IN HUMAN ATHEROSCLEROTIC PLAQUES: IMPLICATIONS FOR ATHEROTHROMBOSIS Michael Worsch, M. Grebe, S. Kanse, B. Parviz, H. Tillmanns, H. Hoelschermann, M. Parahuleva, Germany 568 542 IMAGING MURINE ATHEROTHROMBOSIS: VALIDATION OF SCANNING ELECTRONY MICROSCOPY (SEM) FOR ASSESSING PLAQUE RUPTURE IN MICE A.-L. Charles, P. Tilly, S. Ludwig, A. Sayeh, P. Choquet, Jean-Etienne Fabre, France 685 543 PREVALENCE OF DRUG-DRUG INTERACTION IN THE PRIMARY HEALTH CARE DURING CLOPIDOGREL THERAPY Inga Urtane, K. Pukite, A. Aitullina, A.S. Stokmane, Latvia 544 THE HOMEOSTATIC CHEMOKINE CCL21 PREDICTS MORTALITY IN AORTIC STENOSIS PATIENTS AND IS NECESSARY FOR DEVELOPMENT OF COMPENSATORY CONCENTRIC HYPERTROPHY Trine Ranheim, A.V. Finsen1,2, T. Ueland, I. Sjåstad2,3, E.T. Askevold1,2, M. Lipp, L. Gullestad1,2, G. Christensen2,3, P. Aukrust1,2, A. Yndestad1,2, Norway, Germany 1189 545 A DOUBLE-BLIND RANDOMIZED PLACEBO PILOT STUDY COMPARING AGGRENOX VERSUS PLACEBO IN HEART FAILURE PATIENTS (ASAP-HF TRIAL) Ping-Yen Liu, L.-M. Tsai, C.-H. Lee, J.K. Liao, J.-H. Chen, Taiwan R.O.C., USA 1199 546 DIFFERENTIAL RELATIONSHIPS BETWEEN CYSTEIN AND HOMOCYSTEIN WITH HEMOSTASIS FACTORS IN DYSLIPIDEMIC PATIENTS Philippe Giral, D. Rosenbaum, N. Jacob, A. Carrié, X. Girerd, A. Ankri, France 1298 INTERRELATIONSHIPS BETWEEN CARDIAC DYSFUNCTION, ACTIVATED COAGULATION SYSTEM, PLATELET HYPERACTIVITY AND ENDOTHELIAL DYSFUNCTION IN PATIENTS WITH STABLE CORONARY ARTERY DISEASE Severina V. Golovach, I.V. Golovach, Belarus 1314 547 113 852 POSTERS TRACK 3: RISK FACTORS, EPIDEMIOLOGY, PREVENTION, AND TREATMENT OF CARDIOVASCULAR DISEASES (contd.) Poster Board No. Abstract No 548 INTRINSIC PLATELET REACTIVITY AND THROMBUS BURDEN IN PATIENTS WITH ST-ELEVATION MYOCARDIAL INFARCTION Ioanna Xanthopoulou, G. Tsigkas, A. Damelou, K.C. Theodoropoulos, G. Makris, V. Gizas, G. Kassimis, P. Davlouros, G. Hahalis, D. Alexopoulos, Greece 1439 549 TICAGRELOR VS PRASUGREL ON THE CORONARY BLOOD FLOW VELOCITY IN PATIENTS WITH ACUTE CORONARY SYNDROME UNDERGOING PCI Ioanna Xanthopoulou, N. Koutsogiannis, A. Moulias, A. Kakkavas, E. Mavronasiou, P. Davlouros, G. Hahalis, D. Alexopoulos, Greece 550 ΕFFECTS OF TICAGRELOR ON PLATELET-MEDIATED THROMBOSIS AND INFLAMMATORY RESPONSE IN PATIENTS WITH ACUTE CORONARY SYNDROMES Maria Tsoumani, P. Tatsidou, I. Ntalas, K. Kalantzi, I. Goudevenos, A. Tselepis, Greece 1445 551 CIRCULATING MICRORNAS AS NOVEL BIOMARKERS FOR PLATELET ACTIVATION Anna Zampetaki, P. Willeit, K. Dudek, D. Kaudewitz, A. King, N.S. Kirkby, H.S. Markus, T.D. Warner, S. Kiechl, M. Mayr, UK, Austria 1588 1441 Aneurysms 552 INTRACELLULAR CYCLOPHILIN A IN HUMAN ABDOMINAL AORTIC ANEURYSM IS INFLUENCED BY SIMVASTATIN A. Piechota-Polanczyk, S. Denyanets, M. Mittlboeck, C. Domenig, C. Neumayer, J. Wojta, J. Nanobachvili, M. Klinger, O. Nykonenko, Ihor Huk, Austria, Ukraine 236 553 554 ABDOMINAL AORTIC ANEURYSMS AND CORONARY ARTERY DISEASE: A RETROSPECTIVE POPULATION-BASED STUDY Hassan Al-Thani, A. El-Menyar, A. Tabib, M. AlSulaiti, A. Almalki, Qatar ANGIOGENESIS IN HUMAN THORACIC AORTIC ANEURYSMS Ketty Kessler, R. Vranckx, J.-B. Michel, France 736 1084 Arteriopathy 555 556 557 EFFECTS OF PERIPHERAL ARTERY COMPLIANCE ON EXERCISE CAPACITY IN ELDERLY MALES Wei-Chuan Tsai, C.-H. Chou, J.-Y. Chen, M.-C. Wang, C.-S. Ho, P.-Y. Liu, L.-M. Tsai, C.-H. Wu, Taiwan R.O.C. 81 A CASE OF PSEUDO-XANTHOMA ELASTICUM PRESENTING WITH ISCHAEMIC CLAUDICATION Christopher Lamb, R. Johns, P. Gallagher, A. Odurny, C. Shearman, UK 804 THE COST OF TREATING END STAGE ATHEROSCLEROTIC LOWER LIMB DISEASE IN THE NORTH WEST OF ENGLAND Colin Chan, G. Harrison, G. Lawrence, UK 889 114 POSTERS TRACK 3: RISK FACTORS, EPIDEMIOLOGY, PREVENTION, AND TREATMENT OF CARDIOVASCULAR DISEASES (contd.) Poster Board No. Abstract No 558 PERCUTANEOUS TRANSLUMINAL ANGIOPLASTY (PTA) IN PERIPHERAL ARTERY DISEASE: RESULTS OF A 5 YEARS FOLLOW UP STUDY Alessandro Cavarape, A. Da Porto, M.L. Casagrande, D. Gasparini, L.A. Sechi, Italy 1355 559 PERIPHERAL ARTERIAL DISEASE RISK FACTORS IN RELATIONS TO NEW BIOMARKERS OF INFLAMMATION AND ANGIOGENESIS Sonja Perkov, M.M. Kardum Paro, V. Vidjak, Z. Flegar-Meštrić, Croatia 1447 560 FLOATING THROMBUS IN THE DESCENDING THORACIC AORTA A RARE CAUSE OF SYSTEMIC THROMBOEMBOLIZATION Hassan Al-Thani, A. El-Menyar, Qatar 561 ATHEROSCLEROSIS IN TAKAYASU'S ARTERITIS Ahmed Hatri, F. Kessal, S. Taharboucht, A. Mameri, F. Hamrour, R. Guermaz, S. Zekri, M. Brouri, Algeria 1601 157 Lifestyle and CV risk / Exercise 562 SHORT-TERM EXERCISE TRAINING CHANGES TRIGLYCERIDES MOLECULAR CONTENT OF THE LDL AND HDL PARTICLES AFFECTING THEIR FUNCTIONAL CHARACTERISTICS IN METABOLIC SYNDROME A. Casella-Filho, I.C. Trombetta, P.M. Dourado, Antonio Carlos de Leite Jr, M.C. Sprandel, A. Segre, R.D. Santos, C.E. Negrao, R.C. Maranhao, A.C.P. Chagas, Brazil 34 563 RELATIONSHIPS BETWEEN HDL FUNCTIONAL CHARACTERISTICS AND ENDOTHELIAL VASCULAR FUNCTION AFTER SHORT-TERM EXERCISE TRAINING IN PATIENTS WITH THE METABOLIC SYNDROME A. Casella-Filho, I. Trombeta, P.M. Dourado, Antonio Carlos de Leite Jr, V. Jonke, A. Segre, R.D. Santos, C.E. Negrao, R.C. Maranhao, A.C.P. Chagas, Brazil 35 564 OVARIECTOMY IN RATS IS ASSOCIATED WITH A REDUCTION OF HEPATIC LDLR, LRP1 AND PCSK9 GENE EXPRESSION; IMPACT OF EXERCISE TRAINING Emilienne Tudor Ngo Sock, J.-M. Lavoie, Canada 452 THE EXERCISE HAS DIFFERENT EFFECTS ON COLLAGEN AND ELASTIC FIBERS OF THE AORTA IN NORMAL AND LDL KNOCKOUT MENOPAUSED ANIMALS C. Marchon, Ledimar Brianezi1,2, L. Maifrino3,4, R. Souza, Brazil 711 EFFECTS OF EXERCISES ON THE RIGHT VENTRICLE OF FEMALE MICE SUBMITTED TO OVARIAN HORMONE DEPRIVATION Ledimar Brianezi1,2, K. Ressureição2,3, L. Maifrino2,4, Brazil 713 565 566 567 INFLUENCE OF SHORT-TERM EXERCISE ON THE SIZE OF LIPOPROTEIN PARTICLES AMONG YOUNG HEALTHY SEDENTARY MALES Peter Sabaka, S. Oravec, J. Gajdosik, M. Zelina, A. Dukat, Slovak Republic 757 115 POSTERS TRACK 3: RISK FACTORS, EPIDEMIOLOGY, PREVENTION, AND TREATMENT OF CARDIOVASCULAR DISEASES (contd.) Poster Board No. Abstract No 568 COMPARED OUTCOME IN PATIENTS POST ACUTE CORONARY SYNDROME WITH VERSUS WITHOUT CARDIAC REHABILITATION FOLLOWING THE EVENT Eliezer Klainman, D. Mossinson, R. Cohen, L. Valinsky, A. Yarmolovsky, G. Fink, Israel 781 569 EFFECTS OF CARDIAC REHABILITATION ON ENDOTHELIAL FUNCTION IN PATIENTS WITH CORONARY ARTERY DISEASE Marta Nogueira, T. Silva, A. Abreu, N. Santos, P. Rio, C. Fundinho, S. Silva, R. Ferreira, Portugal 791 570 DO LEISURE POSTER BOARD NO. PHYSICAL ACTIVITY AND SEDENTARY BEHAVIOR AFFECT CARDIOVASCULAR RISK FACTORS ONLY WEAKLY? Gerda-Maria Haas, T. Bertsch, E. Liepold, P. Schwandt, Germany 811 571 DAILY PHYSICAL ACTIVITY RELATED TO COMPOSITE RISK FACTOR SCORE FOR CVD IN CHILDREN Magnus Dencker, T. Tahna, O. Thorsson, M.K. Karlsson, P. Wollmer, L.B. Andersen, Sweden, Denmark 194 572 VISCERAL OBESITY, LIFESTYLE AND PHYSICAL ACTIVITY LEVELS OF BRAZILIANS: TRYING TO CHANGE THE TENDENCY Marcia Braz Rossetti, A.M. Girodo, C.C. Jardim, G.M. Diniz, Brazil 849 573 THE EFFECT OF CHRONIC SUPERVISED PHYSICAL TRAINING ON INFLAMMATORY PARAMETERS IN PERIPHERAL BLOOD IN PREHYPERTENSIVE SUBJECTS Magdalena Filip, J. Głodzik, T. Mikołajczyk, A. Sałakowski, K. Rewiuk, T. Grodzicki, T. Guzik, Poland 876 EXERCISE MEDIATES SELECTED MICRORNA EXPRESSION AND PROMOTES PLAQUE REGRESSION Mahdi Garelnabi, J. Jin, H. Mahini, F. Chai, USA 913 574 575 THE INFLUENCE OF GLYCEMIC CONTROL AND INSULIN RESISTANCE ON EXERCISE CAPACITY IN PATIENTS WITH CORONARY ARTERY DISEASE AND TYPE 2-DIABETES Rune Byrkjeland1,2, E. Edvardsen3,4, I. Unhammer Njerve1,2, M. Aulie, L.A. 1065 Toftegaard, H. Arnesen1,2, I. Seljeflot1,2, S. Solheim1,2, Norway 576 THE ROLE OF TRANSPORTATION ACTIVITY IN IMPROVEMENT OF HEALTHY LIFESTYLE IN THE POPULATION OF MEDICINE STUDENTS Dariusz Kalka1,2, Z.A. Domagala, L. Rusiecki, M. Syrycki, P. Koleda, T. Sebzda, L. Kipinski, A. Bielolus - Wilk, T. Szawrowicz-Pelka, W. Pilecki, Poland 1565 577 INFLUENCE OF LEISURE POSTER BOARD NO. PHYSICAL ACTIVITY ON FITNESS OF ELDERY PATIENS Dariusz Kalka1,2, Z.A. Domagala, L. Rusiecki, A. Rakowska, J. Wojcieszczyk, W. Marciniak, A. Skalska, K. Womperski, W. Pilecki, Poland 1578 116 POSTERS TRACK 3: RISK FACTORS, EPIDEMIOLOGY, PREVENTION, AND TREATMENT OF CARDIOVASCULAR DISEASES (contd.) Poster Board No. Abstract No Lifestyle and CV risk / Miscellaneous 578 ACUTE CORONARY SYNDROME IN COCAINE USERS. ALWAYS VASOSPASM? THE IMPORTANCE OF CARDIOVASCULAR RISK FACTORS María Thiscal López Lluva, E. Marchan Carranza, M.D. Mañas García, M. Marina Breysse, C. Llanos Guerrero, N. Pinilla Echeverri, J. Piqueras Flores, M.C. Espinosa González, J.M. Arizón Muñoz, L. Ruiz-Valdepeñas Herrero, Spain 637 579 SLEEP DISTURBANCES AND 16 YEARS RISK OF STROKE AND BEHAVIORAL HABITS IN FEMALE POPULATION AGED 25-64 YEARS IN RUSSIA Valery Gafarov1,2, D. Panov1,2, E. Gromova1,2, I. Gagulin1,2, A. Gafarova1,2, Russia 720 580 "EATING HABITS AND LIFE STYLE OF THE UNIVERSITARY STUDENTS OF THE SCHOOL OF NURSING" Hazel Ester Anderson Vasquez, C. Wanden-Berghe, E.C. Garrido Zambrano, I.C. Pernalete Bustos, E. Rivera Bernardoni, Venezuela, Spain 794 Lifestyle and CV risk / Tobacco 581 LIPOPROTEINS FROM YOUNG SMOKERS WITH MODERATE EXTENT CAUSED MORE CELLULAR SENESCENCE AND EXHIBITED MORE ATHEROGENIC PROPERTIES 242 Ki-Hoon Park1,2, D.-G. Shin2,3, J.-R. Kim, K.-H. Cho1,2, Republic of Korea 582 FUNCTIONAL IN VITRO CHARACTERIZATION OF SASH1 GENE LINKING SMOKING TO ATHEROSCLEROSIS Henri Weidmann, C. Proust, R. Verdugo, D. Stengel, T. Zeller, S. Blankenberg, L. Tiret, F. Cambien, E. Ninio, France, Germany 383 583 COMPARISON OF THE RESULTS OF EXERCISE TESTING IN SMOKERS AND NON-SMOKERS PATIENTS Haydeh Hashemizadeh, Iran 545 584 ESTIMATION OF SMOKING CESSATION BENEFITS ON CARDIOVASCULAR RISK VIA LIPIDOMICS AND TRANSCRIPTOMICS ANALYSIS OF APOE-/- MICE LIVER Stephanie Boue, H. de Leon, S. Lebrun, M.C. Peitsch, J. Hoeng, Switzerland 602 Lifestyle and CV risk / Therapeutic education 585 THE IMPORTANCE OF THERAPEUTIC EDUCATION IN PRIMARY PREVENTION FOR REDUCING SOME RISK FACTORS OF ATHEROSCLEROSIS Marc Baudet, C. Daugareil, S. Caspar Bauguil, France 117 683 POSTERS TRACK 3: RISK FACTORS, EPIDEMIOLOGY, PREVENTION, AND TREATMENT OF CARDIOVASCULAR DISEASES (contd.) Poster Board No. 586 Abstract No PATIENT COMPLIANCE IMPROVES LDL-CHOLESTEROL GOAL ATTAINMENT IN THE HUNGARIAN MULTI GAP 2012 STUDY Laszlo Mark, I. Reiber, G. Paragh, I. Karadi, G. Pados, I. Mező, Z. Kiss, Hungary 874 587 IMPROVING DRUG ADHERENCE IS CORRELATED WITH BETTER LIPID LOWERING EFFICACY IN HUNGARIAN MULTI GAP 2010-2012 STUDIES Zoltán Kiss, I. Reiber, I. Mező, I. Karadi, G. Paragh, G. Pados, L. Mark, Hungary 954 588 EFFECTS OF GROUP EDUCATION FOR SECONDARY PREVENTION TO PATIENTS WITH ACUTE MYOCARDIAL INFARCTION BY MEDICAL TEAM IN CARDIAC REHABILITATION Chiharu Noda, T. Masuda, M. Kawano, Y. Ebina, A. Igarashi, K. Kamiya, N. Hamazaki, N. Aoyama, S. Niwano, Japan 1233 Lifestyle and CV risk / Psychosocial factors 589 ANXIETY IN PATIENTS WITH METABOLIC SYNDROME BEFORE AND AFTER CORONARY ARTERY BYPASS SURGERY Galina Chumakova1,2, Y. Chugunova, N. Veselovskaya2,3, Russia 809 590 EFFECTS OF EMOTIONAL AND PHYSIOLOGICAL STRESS ON PLAQUE INSTABILITY IN APOLIPOPROTEIN E KNOCKOUT MICE Tao Zhang, H.B. Liu, Y.Z. Zhai, China 963 591 IMPACT OF ANXIETY AND DEPRESSION ON BIOCHEMICAL BLOOD PARAMETERS IN GENERAL LITHUANIAN POPULATION Dovilė Karčiauskaitė, A. Mažeikienė, N. Burokienė, Z.A. Kučinskienė, Lithuania 1137 Nutrition and CV risk / Alcohol 592 VINEATROL AND CARDIOVASCULAR DISEASE: BENEFICIAL EFFECTS OF A VINE-SHOOT PHENOLIC EXTRACT IN A HAMSTER ATHEROSCLEROSIS MODEL Cindy Romain, S. Gaillet, J. Vidé, J. Carillon, J. Ramos, J.-C. Izard, J.-P. Cristol, J.-M. Rouanet, France 260 593 RED WINE EXTRACT OF ONION ON THE PREVENTION AND IMPROVEMENT OF CARDIOVASCULAR DISEASES-A HUMAN CLINICAL TRIAL Chin-Kun Wang, Taiwan R.O.C. 1425 Nutrition and CV risk / Antioxidants 594 NUTRIGENOMICS REVEALS A COMMON MECHANISM OF ACTION OF DIETARY POLYPHENOLS UNDERLYING THEIR ANTI-ATHEROGENIC PROPERTIES C. Morand, A. Mazur, Dragan Milenkovic, France 441 595 EFFECTS OF ONE-YEAR CONSUMPTION OF LUTEIN-ENRICHED EGG YOLKS ON SERUM LIPID AND LIPOPROTEIN CONCENTRATIONS Sanne M. van der Made, T.T.J.M. Berendschot, J. Plat, The Netherlands 556 118 POSTERS TRACK 3: RISK FACTORS, EPIDEMIOLOGY, PREVENTION, AND TREATMENT OF CARDIOVASCULAR DISEASES (contd.) Poster Board No. Abstract No 596 PREVENTIVE EFFECTS OF LYCOPENE AGAINST CARDIOVASCULAR DISEASES IN HIGH DOSE METHIONINE FEED RATS Aicha Yefsah1,2, K. Othmani, R. Taghlit, N. Hamdis, Y. Benazzoug, Algeria 1394 597 RESVERATROL WINE POLYPHENOL RELAXES RAT RENAL ARTERY IN DIABETIC RAT: THE ROLE OF SMOOTH MUSCLE VOLTAGESENSITIVE POTASSIUM CHANNELS L. Gojkovic-Bukarica, J. Markovic-Lipkovski, S. Cirovic, R. Novakovic, H. Heinle, Vladmiri Kanjuh, Serbia, Germany 1620 Nutrition and CV risk / Carbohydrates/fibres 598 HIGH-DENSITY LIPOPROTEINS MODIFIED BY ARTIFICIAL SWEETENER, ASPARTAME AND SACCHARIN EXHIBIT LOSS OF ANTIATHEROSCLEROTIC ACTIVITY WITH EMBRYONIC TOXICITY 294 J.-M. Baek1,2, J.-Y. Kim1,2, Kyung-Hyun Cho1,2, Republic of Korea 599 IMPAIRED METABOLISM AND WORSENING OF ATHEROSCLEROTIC LESIONS OBSERVED AFTER COLA BEVERAGES´ DRINKING IN APO-E (-/-) MICE M. Otero-Losada, S. Mc Loughlin, G. Rodríguez-Granillo, A. Muller, G. Ottaviano, Juan C. Cutrin1,2, J. Milei, Argentina, Italy 1132 600 EFFECT OF CHIOS MASTIC GUM ADMINISTRATION ON LIPID AND GLUCOSE METABOLISM IN STREPTOZOTOCIN-INDUCED DIABETIC MICE I. Georgiadis, T. Karatzas, G. Agrogiannis, Laskarina-Maria Korou, I.S. Vlachos, I. Tzanetakou, I. Doulamis, A. Pantopoulou, N.L. Katsilambros 1,3, D.N. Perrea, Greece 1555 Nutrition and CV risk / Fatty acids 601 CIRCULATING BIOMARKERS AND LIPID CLASSES INDICATIVE OF CARDIOVASCULAR RISK: EFFECTS OF DAIRY FOOD CONSUMPTION Paul Nestel, K. Croft, P. Meikle, T. Mori, Cardiovascular Nutrition, Australia 258 602 EFFECTS OF OLIVE OIL AND CANOLA OIL ON THE LIPID PROFILE IN POSTMENOPAUSAL WOMEN Hazel Ester Anderson Vasquez, P. Perez Martinez, J. Changarotti, I. Fernandez, Y. Hernandez, Venezuela, Spain 771 603 SESAME OIL AND ITS ROLE IN OXIDATION OF ISOLATED LOWDENSITY LIPOPROTEINS AND OF TOTAL SERUM LIPOPROTEINS IN VITRO K. Makedou, S. Iliadis, M. Gogou, E. Kara, Areti Makedou, G. Papageorgiou, Greece 604 TOTAL SERUM AND HDL-PHOSPHOLIPIDS ARE ASSOCIATED TO DIETARY MONOUNSATURATED FATTY ACIDS IN CAD PATIENTS FROM BIZERTA AREA, TUNISIA Y. Nekaies, A. Ben Khalfallah, H. Aoua, K. Charradi, M. Sakly, Nebil Attia, Tunisia 1103 119 803 POSTERS TRACK 3: RISK FACTORS, EPIDEMIOLOGY, PREVENTION, AND TREATMENT OF CARDIOVASCULAR DISEASES (contd.) Poster Board No. 605 Abstract No IMPACT OF SERUM TRANS FATTY ACID LEVEL IN RISKS OF CORONARY ARTERY DISEASE IN JAPAN Kenta Mori, T. Ishida, N. Tanaka, T. Mori, T. Monguchi, M. Sasaki, K. Kondo, M. Hasokawa, H. Nakajima, Y. Haraguchi, L. Sun, T. Yasuda, M. Shinohara, R. Toh, K.-I. Hirata, Japan 1138 Nutrition and CV risk / Miscellaneous 606 607 A DIET-INDUCED ATHEROSCLEROSIS IN RABBIT MODEL PROVIDES AN INSIGHT INTO ESSENTIAL ELEMENTS CONCENTRATIONS IN CARDIOVASCULAR DISEASE Adeniran Sanmi Adekunle, T. Adelusi, J.O. Fatoki, B. Oyedokun, Nigeria EFFECTS OF HYPERCHOLESTEROLEMIA ON TRACE ELEMENTS LEVELS IN RABBIT TISSUES USING ATOMIC ABSORPTION SPECTROSCOPY Magdy Mohammed Ghannam, M.A.K. Abdelhalim, Medical Biophysics, Saudi Arabia 64 703 608 INCREASED COFFEE CONSUMPTION IS ASSOCIATED WITH HIGHER LIKELIHOOD OF ACUTE CORONARY SYNDROME AND ISCHEMIC STROKE NON-FATAL EVENTS: A CASE/CASE-CONTROL STUDY Christina-Maria Kastorini, H.J. Milionis, D. Kantas, V. Euthimiou, E. Trichia, A. Litsardopoulou, V. Nikolaou, K.N. Vemmos, J.A. Goudevenos, D.B. Panagiotakos, Greece 745 609 SPIRULINA PLATENSIS AND PHYCOCYANOBILIN MODULATE THE ATHEROPROTECTIVE ENZYME HEME OXYGENASE (HMOX1) Zbynek Strasky, L. Zemankova, I. Nemeckova, J. Pfeiferova, L. Muchova, I. 785 Subhanova, J. Vanikova, L. Vitek2,3, P. Nachtigal, Czech Republic 610 THE POTENTIAL OF LUPIN PROTEIN TO EXERT ANTIATHEROSCLEROTIC EFFECTS Melanie Bähr, A. Fechner, G. Jahreis, Germany 990 611 BIFIDOBACTERIUM SUPPLEMENTATION: EFFECTS ON PLASMA LIPID PROFILE IN DYSLIPIDEMIC CHILDREN Francesca Abello, P. Cagliero, O. Guardamagna, Italy 1030 612 EFFECT OF GRAPE SEED AND SKIN EXTRACT ON HIGH-FAT DIETINDUCED RENAL LIPOTOXICITY IN RAT K. Charradi, Nebil Attia2,3, F. Limam, E. Aouani1,3, Tunisia 613 WATER INTAKE AND LDL CHOLESTEROL Ronan Roussel1,2, O. Lantieri, B. Balkau, M. Marre, The D.E.S.I.R. Study Group, France 1479 614 EFFECTS OF FENUGREEK AND SAPONINS ON THE BIOMARKERS OF INFLAMMATION AND ENDOTHELIAL ACTIVATION IN STIMULATED HUMAN CORONARY ARTERY ENDOTHELIAL CELLS Radzi Ahmad1,2, T. Rahman, G.R.A. Froemming, H. Nawawi, Malaysia 1530 120 1452 POSTERS TRACK 3: RISK FACTORS, EPIDEMIOLOGY, PREVENTION, AND TREATMENT OF CARDIOVASCULAR DISEASES (contd.) Poster Board No. Abstract No 615 GRAPE SEED AND SKIN EXTRACT MODULATES LIPASE ACTIVITY IN WISTAR RATS FED A HIGH-FAT DIET 1547 K. Charradi1,2, Nebil Attia2,3, F. Limam, E. Aouani2,5, Tunisia 616 CHARACTERISATION OF ATHEROSCLEROSIS LESIONS IN APOE/LDLR-/- MICE FED LOW CARBOHYDRATE, HIGH PROTEIN DIET (LCHP) R.B. Kostogrys, Magdalena Franczyk-Zarow, E. Maslak, I. Czyzynska, A. Drahun, A. Jasztal, B. Sitek, L. Mateuszuk, M. Gajda, S. Chlopicki, Poland 1153 617 CHARACTERIZATION OF PROTEIN PROFILES RELATED TO DIET AND EXERCISE AS MOLECULAR SIGNATURES OF VASCULAR WELLNESS M.C. Duran, R. Toro, J. Alonso, Carmen Rodriguez Leal, I. Tinoco, M.L. Cabeza-Letran, D. Corrales, N. Caro, E. Segura, A. Mangas, Spain 1303 618 CASE CONTROL STUDY OF THE EFFECT OF A NUTRITIONAL STRATEGY «GOURMET NUTRITION» ON THE COMPLIANCE TO CARDIOVASCULAR LIFESTYLES RECOMMENDATIONS Francois Allaert, F. Paillard, T. Coutureau, France 285 EVOLUTION OF CARDIOVASCULAR LIFESTYLE BEHAVIOURS AND LIPID PARAMETERS OCCURRING IN HYPERCHOLESTEROLEMIC PATIENTS CONCOMITANTLY TO THE INTAKE OF PHYTOSTEROLSUPPLEMENTED YOGHURT E. Bruckert, L. Massama, O. Descamps, E. Bosi, Francois Allaert, M.J. Chapman, France, Spain, Belgium, Italy 937 619 Omega-3 fatty acids 620 CALORIC RESTRICTION AND POSTPRANDIAL STRESS MARKERS IN HEALTHY AND OBESE PERSONS UNDER SUPPLEMENTATION WITH N-3 POLYUNSATURATED FATTY ACIDS (PUFA) Malgorzata Malczewska Malec, D. Siedlecka, J.S. Mozwillo, B.K. Wilk, M. Malecki, A.D. Kiec, Poland 108 621 BENEFICIAL CARDIOVASCULAR EFFECTS OF FLAXSEED SUPPLEMENTATION IN STZ- DIABETIC RATS Nilay Tarhan, Y. Fidan, C. Tufan, B. Konuklugil, N. Arı, G. Ozansoy, Turkey 380 622 ASSOCIATION OF SERUM OMEGA-3 TO OMEGA-6 POLYUNSATURATED FATTY ACID RATIO WITH MICROALBUMINURIA IN A POPULATION OF COMMUNITY-DWELLING JAPANESE A. Fukami, Hisashi Adachi, Y. Hirai, M. Enomoto, A. Obuchi, A. Yoshimura, T. Imaizumi, Japan 406 623 ASSOCIATION BETWEEN SERUM N-3/N-6 POLYUNSATURATED FATTY ACID RATIO AND CORONARY AND AORTIC PLAQUE INSTABILITY Yukihiko Momiyama, R. Ohmori, R. Kato, H. Taniguchi, F. Ohsuzu, Japan 497 121 POSTERS TRACK 3: RISK FACTORS, EPIDEMIOLOGY, PREVENTION, AND TREATMENT OF CARDIOVASCULAR DISEASES (contd.) Poster Board No. Abstract No 624 OMEGA 3 FATTY ACIDS REDUCE CARDIOVASCULAR RISK BY IMPROVING THE METABOLISMS OF SPHINGOLIPIDS AND TRIGLYCERIDES IN VLDL Veronique Ferchaud Roucher, C. Nael, A. Aguesse, M. Krempf, K. Ouguerram, France 625 OMEGA-3 FATTY ACID DECREASES BOTH SYSTEMIC INFLAMMATION OF RETICULO-ENDOTHELIAL SYSTEM AND INFLAMMATION AT VASCULAR PLAQUE Sungeun Kim, H.S. Seo, E.J. Kim, J.H. Na, J.H. Park, C.-G. Park, C.U. Choi, H.E. Lim, J.W. Kim, S.-W. Rha, D.J. Oh, Republic of Korea 690 626 THE PARADOX OF OMEGA 3 PUFAS: ATHEROPROTECTIVE ALTHOUGH HIGHLY SUSCEPTIBLE TO PEROXIDATION Cecile Gladine, M. Zmojdzian, J. Newman, T. Durand, L. JoumardCubizolles, M.-A. Verny, J.-M. Galano, C. Demougeot, O. Berdeaux, E. Pujos-Guillot, A. Mazur, B. Comte, France, USA 627 MARINE OIL EXTRACTED FROM THE COPEPODE CALANUS FINMARCHICUS REDUCES AORTA ATHEROSCLEROSIS IN FEMALE APOLIPOPROTEIN E-DEFICIENT MICE Karl-Erik Eilertsen, H.K. Mæhre, I.-J. Jensen, H. Devold, E.O. Elvevoll, B. Østerud, Norway 1446 628 DOCOSAHEXAENOIC ACID SUPPLEMENTATION IN APOLIPOPROTEINE DEFICIENT MICE EXPOSED TO INTERMITTENT HYPOXIA: EFFECT ON ATHEROGENESIS PREVENTION Laetitia Van Noolen1,2,3, M. Bäck, C. Arnaud, A. Rey, M.H. Petrii, P. Levy1,3, 1457 P. Faure1,2,3, F. Stanke-Labesque1,2,3, France, Sweden 629 DIETARY ENRICHMENT WITH MARINE OIL AND TAURINE REDUCE HEPATIC EXPRESSION OF PROINFLAMMATORY GENES WITHOUT AFFECTING ATHEROSCLEROSIS IN APOLIPOPROTEIN E-DEFICIENT MICE Ida Johanne Jensen, H. Mæhre, H. Devold, E. Elvevoll, B. Østerud, K.-E. Eilertsen, Norway 1490 630 INCREASE IN THE SERUM LEVEL OF EICOSAPENTAENOIC ACID IS ASSOCIATED WITH THE STABILIZATION OF CORONARY VULNERABLE PLAQUE Takayoshi Nemoto, A. Hirata, Y. Ueda, Japan 1560 631 YOUNGER PATIENTS WITH STABLE CORONARY ARTERY DISEASE HAVE LOWER RATIO OF SERUM EICOSAPENTAENOIC ACID TO ARACHIDONIC ACID Takayoshi Nemoto, M. Nishio, Y. Ueda, Japan 1563 122 601 1438 POSTERS TRACK 3: RISK FACTORS, EPIDEMIOLOGY, PREVENTION, AND TREATMENT OF CARDIOVASCULAR DISEASES (contd.) Poster Board No. Abstract No Phytosterols 632 CARDIOVASCULAR PROFILE OF CONSUMERS OF A PHYTOSTEROLENRICHED YOGURT IN A REAL-LIFE SETTING: A FRENCH OBSERVATIONAL TRANSVERSAL STUDY J. Dallongeville, F. Paillard, Eric Bruckert, G. Naelten, P. Picard, E. Van Ganse, France 604 634 GENETIC BASIS FOR HETEROGENEITY OF RESPONSE OF LDL CHOLESTEROL TO PLANT STEROLS Dylan Stapenhorst MacKay, D. Baer, P. Eck, P.J. Jones1,3, Canada, USA 1645 Treatment / Miscellaneous 635 RESVERATROL PROMOTES EXPRESSIONS OF SIRT1 AND LPL TO INHIBIT TG ACCUMULATION IN DIFFERENTIATED 3T3-L1 PREADIPOCYTES Haruki Imamura, T. Yamaguchi, Y. Sato, N. Ban, H. Kawana, D. Nagayama, A. Nagumo, M. Ohira, K. Endo, A. Saiki, N. Ishihara, F. Watanabe, K. Shirai, I. Tatsuno, Japan 653 636 IN VIVO PHARMACOLOGICAL ACTIVITY OF NOVEL 5-FLUORO-N-(9,10DIHYDRO-9,10-DIOXOANTHRACEN-8-YL)-1H-INDOLE-2-CARBOXAMIDE DERIVATIVES ON PLASMA LIPID PROFILE OF TRITON-WR-1339INDUCED WISTAR RATS Ghassan Shattat, T. Al-Qirim, G. Abu Sheikha, Y. Alhiari, K. Sweidan, R. Alqirim, Jordan 86 637 ATHEROPROTECTION OF ANTI-LDL(-) SCFV CONJUGATED TO NANOPARTICLES IN EXPERIMENTAL ATHEROSCLEROSIS Marcela Frota Cavalcante, S.M. Kazuma, A.R. Pohlmann, S.S. Guterres, E.A. Bender, M.D. Adorne, D.S.P. Abdalla, Brazil 150 PROBUCOL AND CILOSTAZOL EXERT A SYNERGISTIC ANTIATHEROGENIC EFFECT IN CHOLESTEROL-FED RABBITS Enqi Liu, Y. Chen, S. Zhao, J. Fan, China, Japan 171 638 639 CSL112, A NOVEL FORMULATION OF HUMAN APOLIPOPROTEIN A-I, IN HEALTHY SUBJECTS ENHANCES CHOLESTEROL EFFLUX CAPACITY AND MOBILIZES CHOLESTEROL FROM TISSUES Andreas Gille, R. Easton, S.D. Wright, C.L. Shear, Australia, USA 330 640 EFFECT OF MYRICETIN TREATMENT ON LIPOPROTEIN METABOLISM IN 13-HODE EXPOSED HEPG2 CELLS Mahdi Garelnabi, H. Mahini, USA 535 641 ADD-ON EFFECT OF PROBUCOL IN ATHEROSCLEROTIC, CHOLESTEROL-FED RABBITS TREATED WITH ATORVASTATIN Y. Keyamura1,2, C. Nagano, M. Kohashi, M. Niimi, M. Nozako, T. Koyama, R. Okutsu, A. Fukuda, K. Mitani, H. Itabe, Tomohiro Yoshikawa, Japan 536 123 POSTERS TRACK 3: RISK FACTORS, EPIDEMIOLOGY, PREVENTION, AND TREATMENT OF CARDIOVASCULAR DISEASES (contd.) Poster Board No. Abstract No 642 THE BOTANICAL PRODUCT XUEZHIKANG (XZK): ITS EFFICACY AND SAFETY FOR LIPID-LOWERING THERAPY WHEN COMPARED TO PLACEBO Patrick M. Moriarty, Z. Duan, S. Guo, P. Liu, Y. Zhang, S. Li, WPU-201 Study Group, USA, China 630 643 EDARAVONE ATTENUATES ANGIOTENSIN II-INDUCED ATHEROSCLEROSIS AND ABDOMINAL AORTIC ANEURYSMS IN APOLIPOPROTEIN E DEFICIENT MICE Haruhito Adam Uchida, H. Uchida, R. Umebayasi, K. Shikata, H. Makino, Japan 1290 644 THE IMPACT OF STRATEGIC UK NATIONAL HEALTH SERVICE (NHS) FUNDING ON THE PATIENT RECRUITMENT TO“ATHEROTHROMBOSIS” RESEARCH STUDIES Alistair S. Hall, D.E. Newby, C.P. Gale, R.G. Gillott, S. Scarlett, S.M. Wood, J.D. Gower, B. Williams, M.J. Caulfield, UK NHS Atherothrombosis Research Network, UK 1338 645 THE IMPACT OF COORDINATED NATIONAL SYSTEMS TO AID PATIENT RECRUITMENT AND FOLLOW-UP IN “ATHEROTHROMBOSIS” RESEARCH: THE EMMACE-3 STUDY Christopher P. Gale, R.G. Gillott, R. Khatib, J.H. Barth, C. Forrest, R.E. Maindonald, K.L. Willan, P.D. Batin, S. Scarlett, S.J. Howell, D. Lawson, J.D. Gower, D.E. Newby, B. Williams, M.J. Caulfield, A.S. Hall, the UK NHS Atherothrombosis Research Network, UK 1349 646 AMP-ACTIVATED PROTEIN KINASE ACTIVATION BY XANTHOHUMOL AMELIORATES ATHEROSCLEROTIC PLAQUE FORMATION, HYPERCHOLESTEROLEMIA AND HEPATIC STEATOSIS IN APOEDEFICIENT MICE Branislav Radovic, P. Doddapattar, J.V. Patankar, S. Obrowsky, K. Jandl, C. Nusshold, D. Kolb, N. Vujic, M. Goeritzer, H. Ahammer, G. Hoefler, W. Sattler, D. Kratky, Austria 1463 647 ANTIBODIES AGAINST OXIDIZED BUT NOT NATIVE CARDIOLIPIN AND PHOSPHATIDYLSERINE AS NOVEL PROTECTION MARKERS IN ATHEROSCLEROSIS DEVELOPMENT A. Frostegård, U. de Faire, Johan Frostegård, Sweden 1599 Treatment / Blood pressure treatment 648 HIGH-DOSE ARB VERSUS ARB PLUS CCB COMBINATION THERAPY FOR SUPPRESSING CAROTID ATHEROSCLEROSIS IN HYPERTENSIVE PATIENTS WITH HYPERCHOLESTEROLEMIA Yasunori Sawayama, Japan 49 649 COMPARISON OF THE EFFECT OF M - AND N-CHOLINOBLOCKERS AND VAGOTOMY ON PHYSICOCHEMICAL PROPERTIES OF LIPOPROTEINS IN RAT BLOOD PLASMA Nina Solomonovna Parfenova, A.S. Kuznetsov, Russia 124 87 POSTERS TRACK 3: RISK FACTORS, EPIDEMIOLOGY, PREVENTION, AND TREATMENT OF CARDIOVASCULAR DISEASES (contd.) Poster Board No. 650 Abstract No EFFECTS OF ALISKIREN ON BLOOD PRESSURE, RENAL AND CARDIAC FUNCTION, BAPWV AND CAROTID ARTERIAL ELASTIC MODULUS IN HYPERTENSIVE PATIENTS Toshio Yamagishi, K. Omata, H. Hasegawa, H. Kanai, Japan 299 651 EXTENDED RELEASE NIACIN LOWERS IN VITRO HDL OXIDIZABILITY AND MEDIATORS OF VASCULAR INFLAMMATION IN STATIN TREATED DYSLIPIDEMIC PATIENTS R. Yadav, Y. Liu, S. Kwok, V. Charlton-Menys, M. France, R. Eatough, S. Hama, N. Younis, B.J. Ammori, B. Issa, Handrean Soran, UK 1098 652 EFFECT OF ALISKIREN ON (PRO)RENIN RECEPTOR EXPRESSION AND ACTIVITY IN CULTURED SMOOTH MUSCLE CELLS Nicola Ferri, F. Panariti, G. Maiocchi, A. Corsini, Italy 653 LONG TERM EFFECT OF SPECIFIC TREATMENT OF PRIMARY ALDOSTERONISM ON CAROTID INTIMA MEDIA THICKNESS Robert Holaj, J. Rosa, T. Zelinka, B. Strauch, O. Petrak, D. Michalsky, K. Novak, J. Widimsky, Czech Republic 1596 1255 Intravascular procedures 654 SUSTAINED PHARMACOLOGIC PRECONDITIONING OF THE CONDUIT ARTERY WITH SILDENAFIL: A HUMAN IN VIVO STUDY K. McLaughlin, A. Liuni, John David Parker, Canada 906 655 LOW LEVEL LASER THERAPY PROTECT INFLAMMATION-INDUCED ENDOTHELIALDYSFUNCTION Yu-Jung Cheng, Taiwan R.O.C. 570 656 PREDICTORS OF THE ADVERSE OUTCOMES AFTER CORONARY STENTING Galina Chumakova1,2, N. Veselovskaya2,3, V. Elikomov1,3, O. Gritsenko1,2, Russia 741 657 THE FEASIBILITY OF ENDOVASCULAR AORTIC BIOPSY DURING ENDOVASCULAR INTERVENTIONS Michał Stanisić, W. Majewski, J. Kulesza, P. Majewski, A. Marszałek, A. Zarzecka, G. Oszkinis, Poland 766 658 PSEUDOANEURYSM OF THE ASCENDING AORTA FOLLOWING RIGHT CORONARY STENTING Jose Rubio Alvarez, J. Sierra Quiroga, B. Adrio Nazar, J. Garcia Carro, L. Reija Lopez, A. Gandara, C. Rubio Taboada, Spain 22 659 NONINVASIVE IDENTIFICATION OF LEFT MAIN CORONARY RESTENOSIS Milana Zabunova, I. Mintale, I. Narbute, S. Jegere, I. Zakke, A. Erglis, Latvia 32 660 NON-INVASIVE FOLLOW-UP - A KEY POINT FOR PATIENTS AFTER LEFT MAIN PERCUTANEOUS CORONARY INTERVENTION I. Mintale, Milana Zabunova, I. Narbute, S. Jegere, I. Zakke, A. Erglis, Latvia 33 125 POSTERS TRACK 3: RISK FACTORS, EPIDEMIOLOGY, PREVENTION, AND TREATMENT OF CARDIOVASCULAR DISEASES (contd.) Poster Board No. Abstract No Miscellaneous 665 APOA-I DEPLETION AND ATHEROSCLEROSIS IN APOE-KO MICE: THE RIGHT WAY TOWARDS A MURINE MODEL OF OCCLUSIVE CORONARY ARTERY DISEASE? G. Ganzetti, Marco Busnelli, C. Parolini, S. Manzini, F. Dellera, C.R. Sirtori, G. Chiesa, Italy 1507 666 CURCUMIN MODULATION OF ATHEROSCLEROSIS AND HEPATOSTEATOSIS IN LDLR-/- MICE Mohsen Meydani, S.T. Hasan, J.-M. Zingg, P. Kwan, D. Smith, USA 916 667 ASPIRIN RESISTANCE OCCURS ALSO IN YOUNG HEALTHY MEN AND IS ASSOCIATED WITH PREACTIVATION OF PLATELETS Agnieszka Janus1,2, P. Ilnicka1,2, M. Jakubowski, E. Szahidewicz-Krupska1,2, 188 A. Szuba1,2, A. Doroszko1,2, Poland 668 ENDOTHELIAL DYSFUNCTION IN YOUNG HEALTHY MEN IS ASSOCIATED WITH ASPIRIN RESISTANCE Adrian Doroszko1,2, M. Jakubowski, A. Janus1,2, P. Ilnicka1,2, E. Szahidewicz-Krupska1,2, A. Szuba1,2, Poland 1156 669 ENDOTHELIAL DYSFUNCTION AND ASPIRIN RESISTANCE IN YOUNG HEALTHY MEN IS RELATED TO INCREASED ACTIVITY OF THE RENNIN-ANGIOTENSIN-ALDOSTERONE SYSTEM A. Doroszko1,2, P. Ilnicka1,2, A. Janus1,2, Maciej Jakubowski, E. Szahidewicz-Krupska1,2, A. Szuba1,2, Poland 187 670 DO LOW HDL CHOLESTEROL LEVELS PREDICT DIABETES MELLITUS ONSET? Alp Burak Catakoglu, V. Aytekin, E. Usta, M.G. Ercan, H. Kurtoglu, M. Sener, H. Celebi, S. Aytekin, Turkey 707 671 CARDIOVASCULAR RISK PROFILE OF PATIENTS WITH SPONDYLOARTHRITIS Charalampos Papagoras, T.E. Markatseli, P. Margariti, A.K. Zikou, Y. Alamanos, A.A. Drosos, Greece 672 RELATIONSHIP BETWEEN CETP AND CHOLESTEROL EFFLUX Raja Chaaba, S. Mehri, N. Attia, S. Hammami, M. Smaoui, K. Ben Hamda, A. Nakbi, N. Koubaa, M. Hammami, Tunisia 1173 673 CAROTID ATHEROSCLEROSIS IN ASYMPTOMATIC NEWLY DIAGNOSED TYPE 2 DIABETIC SUBJECTS Marta Catalan, Z. Herreras, M. Pinyol, A. Sala, R. Gilabert, E. Ortega, Spain998 674 PANORAMIC RADIOGRAPHY AND COLOR DOPPLER IN THE DIAGNOSIS OF CALCIFIED CAROTID ATHEROMATOUS PLAQUES T.Q. Abreu, Sebastião Barreto De Brito Filho, K.P.F.d. Sales, E.B. Ferreira, A.E.F.D. Oliveira, Brazil 126 217 113 POSTERS TRACK 3: RISK FACTORS, EPIDEMIOLOGY, PREVENTION, AND TREATMENT OF CARDIOVASCULAR DISEASES (contd.) Poster Board No. 674 Abstract No PANORAMIC RADIOGRAPHY AND COLOR DOPPLER IN THE DIAGNOSIS OF CALCIFIED CAROTID ATHEROMATOUS PLAQUES T.Q. Abreu, Sebastião Barreto De Brito Filho, K.P.F.d. Sales, E.B. Ferreira, A.E.F.D. Oliveira, Brazil 113 675 FETUIN-A AND CARDIOVASCULAR MORBIDITY AND MORTALITY IN PATIENTS WITH PERIPHERAL VASCULAR DISEASE IN NON-DIALYSED PATIENTS Zoltan Szeberin, M. Fehérvári, M. Krepuska, A. Apor, H. Sarkadi, L. Entz, B. Merkely, Hungary 82 676 MULTIPLE RISK FACTORS AND CAROTID ATHEROSCLEROSIS IN JAPANESE IN THE PRIME OF LIFE Wakoh Takahashi, T. Uesugi, T. Ohnuki, S. Takizawa, Japan 677 BIOMARKERS OF ATHEROSCLEROTIC PLAQUES INSTABILITY AND THEIR RELATION WITH LONG-TERM RESULTS OF SURGICAL MYOCARDIAL REVASCULARIZATION Yulia Ragino, A. Chernyavskiy, S. Tcimbal, L. Scherbakova, Y. Polonskaya, M. Voevoda, Russia 468 678 INTRA-FAMILIAL ASSOCIATIONS OF CARDIOVASCULAR RISK FACTORS IN 515 HEALTHY FAMILIES - THE PEP FAMILY HEART STUDY 2007 Peter Schwandt, T. Bertsch, E. Liepold, G.-M. Haas, Germany 334 806 679 "LIFESTYLE AND HABITS FOOD OF STUDENTS NEW INCOME THE SCHOOL OF NUTRITION AND DIETETICS" Hazel Ester Anderson Vasquez, C. Wanden-Berghe, D.C. Araujo Castillo, E.R. Labrador Aldana, K.D. Rodríguez Ortega, Venezuela, Spain 799 680 THE ROLE OF DRUGS WITH REDUCING EFFECTS ON OXIDATIVE STRESS, PLATELETS HYPERACTIVITY AND ENDOTHELIAL DYSFUNCTION IN CORONARY ARTERY DISEASE Alexandru Covaciu, E. Bobescu1,2, N. Aldulea, Romania 1158 DEVELOPMENT OF NEW RAC1 INHIBITORS AS POTENTIAL PHARMACOLOGICAL AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS Sergio Kevin Bernini, A. Contini, A. Corsini, N. Ferri, Italy 1256 682 683 APO C-III CORRELATES WITH ARTERIAL STIFFNESS IN PATIENTS WITH CLINICAL DIAGNOSIS OF FAMILIAL HYPERCHOLESTEROLEMIA (FH) Małgorzata Waluś-Miarka, B. Idzior-Waluś, D. Czarnecka, M. Sanak, P. Miarka, W. Wojciechowska, M. Kloch-Badełek, M.T. Małecki, E. Woźniakiewicz, J. Starzyk, Poland 724 127 POSTERS TRACK 3: RISK FACTORS, EPIDEMIOLOGY, PREVENTION, AND TREATMENT OF CARDIOVASCULAR DISEASES (contd.) Poster Board No. Abstract No 684 LECITHIN CHOLESTEROL ACYLTRANSFERASE RS 5922 AND RS5923 SINGLE-NUCLEOTIDE POLYMORPHISMS AND INSULIN RESISTANCE: A BRAZILIAN POPULATION STUDY Eliane Soler Parra, N.B. Panzoldo, V.S. Nunes, J. Metso, M. Jauhiainen, V.H.S. Zago, D.Z. Scherrer, F. Alexandre, E.R. Nakandakare, E.C.R. Quintão, E.C. de Faria, Brazil, Finland 1649 685 PATIENT DETERMINANTS OF HYPERCHOLESTEROLEMIA UNDERTREATMENT IN CENTRALIZED PAN-RUSSIAN SURVEY ON THE UNDERTREATMENT OF HYPERCHOLESTEROLEMIA (CEPHEUS) Yunona Khomitskaya. Eliane Soler Parra, Sergey Boytsov, Moscow, Russia 838 686 INFLAMMATORY RESPONSE MODIFICATION AFTER CARDIAC RESYNCHRONIZATION IN HEART FAILURE PATIENTS-PRELIMINARY RESULTS Ana Abreu, M. Mota Carmo, T. Pinheiro, H. Santa Clara, M. Selas, P. Cunha, M. Oliveira, M. Nogueira Siva, R. Ferreira, Lisbon, Portugal 1382 687 MARKEDLY INCREASED FREQUENCY OF UNDETECTED PERIPHERAL ARTERIAL DISEASE IN THE ELDERLY WITH DEMENTIA Ilker Tasci, U. Safer, I., Naharci, E. Bozoglu, M. Gezer, O. Demir, H. Doruk, Ankara, Turkey 823 128 INDEX Arteriosclerosis, Thrombosis, and Vascular Biology The forum for publication of basic, translational, clinical, and population research in the area of arteriosclerosis, thrombosis, and vascular biology Download the iPad app for a print-like, full-text experience Read and search with ease on your Internetenabled smartphone editOR-in-chief Alan Daugherty, PhD, DSc, FAHA atvb.ahajournals.org A subscription includes access to ATVB online and on your iPad®. Submit Your Manuscript Join the aha* http://atvb-submit.aha-journals.org Call: 1-800-787-8984 (United States) +1-301-223-2307 (Rest of World) Visit my.americanheart.org/membership 6.368 With an Impact Factor of 6.368, ATVB ranks 3rd among 68 journals in Peripheral Vascular Disease and 7th among 68 journals in Hematology subject categories. 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L Agianniotis, A. .................................... 60 Agouridis, A.D. ................................... 76 Agrawal, D.K. ..........................43, 51, 60 Agrogiannis, G. ................................ 119 Aguesse, A. ...................................... 122 Aguirre, A.C........................................ 85 Ahammer, H. .................................... 124 Aherrahrou, Z. .................................... 68 Ahimastos, A.A. ................................. 44 Ahluwalia, A. ...................................... 65 Ahmad, R.......................................... 120 Ahn, J. ............................................... 111 Ahn, T.H. ...............................89, 95, 102 Ahnmark, A. ....................................... 35 Ahotupa, M. ........................................ 69 Ahuad, L. .................................... 96, 102 Äijänen, T. .......................................... 70 Aittokallio, T........................................ 22 Aitullina, A. ....................................... 113 Aizpuru, N........................................... 80 Akao, H. .............................................. 45 Akbar, N. ............................................. 64 Akbar, S. ........................................... 106 Akhter, T. ............................................ 93 Akimoto, K. ......................................... 58 Akulich, N.V........................................ 77 Aladinsky, V. ...................................... 70 Alamanos, Y. .................................... 126 Alavi, A. ............................................... 45 Albayrak, G. ....................................... 60 Alberici, L.C. ....................................... 90 Albertini, J.-P...................................... 75 Albizem, M.......................................... 44 Aldulea, N. .................................. 92, 127 Alekseeva, G.V. ................................. 99 Alexandra, G. ..................................... 79 Alexandre, F. .........................71, 78, 128 Alexescu, T. ............................. 106, 107 Alexescu, T.G. ................................. 104 Alexopoulos, D................................. 114 Alexopoulou, Z. ................................ 112 Alfakry, H. ........................................... 61 Alhiari, Y. .......................................... 123 Ali, H.................................................... 11 A Aalkjær, C. ............................................ 8 Abbate, R. ..................................... 70, 95 Abdalla, D.S.P. ................................. 123 Abdelhalim, M.A.K. .................. 104, 120 Abdeli, L. ............................................. 11 Abdelkadhem, H. ............................... 65 Abdollahi, M. ........................... 45, 49, 50 Abdul, Rahman, T.H. ............. 58, 66, 72 Abdulhannan, P. ................................ 94 Abedpour, Dehkordi, A. ..................... 70 Abello, F. ..................................... 81, 120 Abifadel, M. ................................... 26, 50 Abot, A........................................... 29, 37 Abreu, A. ..................................... 53, 116 Abreu, T.Q. ............................... 126, 127 Abt, M. ................................................. 77 Abu, Sheikha, G. .............................. 123 Achenbach, K. .................................. 106 Achenbach, S. .................................... 68 Acin, F. .................................... 65, 68, 94 Acín, García, F. ................................ 100 Ackermans, M. ................................... 36 Acosta, E. ............................................ 38 Acuña-Alonzo, V. ............................... 99 Adachi, H. ........................... 35, 109, 121 Adamkova, V. ..................................... 99 Adamova, I.......................................... 86 Adamski, J. ................................. 75, 110 Adekunle, A.S................................... 120 Adelusi, T. ......................................... 120 Adlanmerini, M. .................................. 37 Adorne, M.D. .................................... 123 Adorni, M.P. ........................................ 71 Adrio, Nazar, B. .......................... 88, 125 Adzhiev, R. ......................................... 86 Aerts, H. .............................................. 55 Afanasieva, O. .............................. 86, 87 Afonso, M. ........................................... 30 Afonso, P. ........................................... 83 Agakov, F. ........................................... 36 Aggeli, C.............................................. 38 129 Al-Jenabi, A. ....................................... 65 Alla, F. ................................................. 32 Allaert, F. ........................................... 121 Allemand, H. ....................................... 32 Allemandou, D. ................................... 77 Almalki, A. ......................................... 114 Almoudi, M. ......................................... 98 Alonso, J. .................................... 57, 121 Alonso, L. ............................................ 80 Alqirim, R. ......................................... 123 Al-Qirim, T. ........................................ 123 Alsac, J.-M. ......................................... 38 AlSulaiti, M. ....................................... 114 Altay, S. ............................................... 94 Altendorf, R. ........................................ 68 Al-Thani, H. ....................... 110, 114, 115 Altwegg, L.A. ...................................... 47 Alvarez, E............................................ 57 Alvarez, I. ............................................ 38 Alvarez-León, E.................................. 99 Alves, A.C. .......................................... 81 Alves, R. .............................................. 90 Alves, T. .............................................. 53 Amadio, P. .......................................... 34 Amar, M. .............................................. 22 Amaral, J.B. ........................................ 85 Amarenco, P. .......................... 34, 56, 57 Amati, G. ............................................. 99 Ametamey, S.M.................................. 98 Amigó, N. ............................................ 36 Aminpour, S. ....................................... 39 Ammori, B.J. ............................... 72, 125 Amouyel, P. ........................................ 54 Amstutz, C. ......................................... 17 Anagnostopoulos, A. ......................... 82 Anagnostopoulou, K. ......................... 84 Anastassopoulou, J. .................. 97, 104 Andersen, L.B................................... 116 Andersen, M.R. .................................... 8 Anderson, L. ....................................... 56 Anderson, Vasquez, H.E. 117, 119, 127 Andia, M.E. ......................................... 58 André, P. ............................................. 66 Andréasson, A.-C. ............................. 35 Andres-Lacueva, C. ........................... 33 Andrienko, A. ................................... 107 Angelico, F. ........................................ 84 Angelin, B. ...............................39, 76, 83 Anghel, M. .......................................... 91 Ankri, A. ............................................ 113 Annema, W. ................................. 49, 72 Anniballi, G. ........................................ 43 Annuzzi, G. ......................................... 43 Antlanger, M. ...................................... 49 Antonazzo, Panico, R. .................... 107 Antoniades, C. ................................. 112 Antoniadis, A.P. ........................... 29, 55 Antonopoulos, A.S. ......................... 112 Antunes, R.......................................... 11 Aoua, H. ...................................... 79, 119 Aouani, E. ..........................103, 120, 121 Aouichat, Bouguerra, S. ................... 74 Aoyama, N.................................. 56, 118 Apor, A. ............................................. 127 Appenzeller, B. ................................ 106 Arai, T. ................................................ 62 Araujo, Castillo, D.C........................ 127 Araujo, D.B. .................................. 76, 96 Araújo, H.A. ........................................ 62 Arbit, E. ............................................. 108 Arca, M. ............................. 10, 15, 31, 84 Arca, Marcello ...................................... 6 Arciello, M. .......................................... 16 Arefieva, T. ......................................... 47 Arens, R. ....................................... 41, 47 Arfian, N.............................................. 11 Arı, N. ................................................ 121 Arizón, Muñoz, J.M. ........................ 117 Arnaboldi, L. ................................. 33, 62 Arnal, J.-F. ...............................29, 37, 49 Arnal, M. ............................................. 74 Arnaud, C. .................................. 64, 122 Arnesen, H. ................................ 55, 116 Aronov, D.M. .................................... 108 Arós, F. ............................................... 35 Arregui, M. .......................................... 32 Artemeva, N. ...................................... 87 Arteta, D. ............................................ 80 Arun, M. .............................................. 60 Arun, M.Z. ........................................... 59 130 Asciutto, G. ......................................... 75 Asehnoune, K. .................................... 76 Ashikhmin, Y....................................... 39 Askevold, E.T. .................................. 113 Astola, N.............................................. 63 Asztalos, B. ......................................... 22 Attia, N...79, 85, 103, 104, 119, 120, 121, 126 Aubert, J.-F. ........................................ 17 Auclair, M. ................................... 83, 100 Audigier, Y. ......................................... 59 Auerbach, B. ....................................... 22 Aujard, F.............................................. 64 Aukrust, P. ...................... 65, 80, 86, 113 Aulie, M. ............................................ 116 Auriac, A.............................................. 52 Averna, M. ............................... 23, 51, 86 Averna, M.R. ....................................... 81 Averna, Maurizio ................................ 16 Avgeri, S.............................................. 95 Ayabe, M. ............................................ 54 Ayari, H........................................ 63, 101 Aydinalp, A........................................ 109 Aydınalp, A. ................................ 89, 107 Aytekin, S. ......................................... 126 Aytekin, V. ......................................... 126 Ayyobi, A. ............................................ 40 Azahri, N.S.................................... 37, 38 Baetta, R............................................. 94 Bagdonaite, L. .................................... 79 Bagheri, B........................................... 66 Bähr, M. ............................................ 120 Bahs, G. ............................................ 103 Bajraktari, G. ................................ 98, 99 Bakker, S.J.L...................................... 49 Bakker-Arkema, R. ............................ 22 Bal, U.A....................................... 89, 107 Balachonova, N. ................................ 88 Balakhonova, T. ................................. 91 Baldi, S. ........................................ 20, 35 Baleanu-Curaj, A. .............................. 45 Balkau, B. ......................................... 120 Balla, G. .............................................. 29 Balla, J. ............................................... 29 Ballantyne, C.M. ............................ 9, 44 Ballantyne, Christie ............................. 9 Balsano, C. ......................................... 16 Ban, N. ......................... 31, 109, 111, 123 Banach, M. ...................... 45, 49, 50, 102 Bandemer, J. ...................................... 70 Bantubungi, K. ................................... 28 Bantubungi-Blum, K. ....................... 105 Banu, I............................................... 105 Banzetti, G.......................................... 86 Baptista, J........................................... 91 Baragetti, A. ..........................67, 68, 112 Baragetti, I. ....................................... 112 Baratta, F. ........................................... 84 Barbieri, S.S. ...................................... 34 Barbieri, V........................................... 96 Barbosa, D.S.................................... 109 Barbosa, S.A. ..................................... 43 Barbosa, S.P. ..................................... 85 Barešić, M. ......................................... 82 Bargalló, N.......................................... 26 Barghan, H. ...................................... 107 Barlera, S.......................................... 100 Barlow, C.K. ....................................... 30 Baroni, M. ......................................... 110 Barrett, P.H.R. ........................... 22, 103 Barrett-Connor, E. ............................... 7 Barrios, E. ......................................... 101 Barrot, S. .................................... 63, 101 B Babjakova, E. ..................................... 99 Bacerra, D. ........................................ 103 Bach, K. ............................................... 95 Bäck, M. ................................ 64, 66, 122 Bäcklund, A......................................... 63 Backteman, K. .............................. 66, 67 Badimon, L............................................ 6 Bae, J. ........................................... 38, 59 Bae, J.U. ............................................. 59 Bae, K.R. ........................................... 112 Baek, J.-M. ........................................ 119 Baer, D. ............................................. 123 Baertschi, A.J. .................................... 59 Baerwald, C. ..................................... 107 131 Barter, P. ......................................... 4, 13 Barter, P.J. .......................................... 27 Barth, J.H. ......................................... 124 Bartrés-Faz, D. ................................... 26 Basha, N. ............................................ 72 Baskar, K. ........................................... 60 Basslé, E. .......................................... 104 Bast, A. ................................................ 74 Basta, G. ............................................. 59 Batin, P.D. ......................................... 124 Baud, S................................................ 61 Baudet, M. ......................................... 117 Baum, C. ....................................... 44, 87 Baumgartner, S. ................................. 74 Bays, H. ............................................... 44 Bays, H.E. ........................................... 86 Beck, K. ............................................... 98 Beck-Nielsen, H. ................................ 50 Becquer, M.A. ..................................... 38 Bedford, D. .................................... 31, 76 Bednarek, M. ...................................... 73 Bedros, R.J. ...................................... 102 Beghin, L. .............................................. 7 Bégu-Le, Corroller, A....................... 101 Behrendt, M. ....................................... 10 Behrensen, M. .................................... 68 Bekers, O. ........................................... 74 Bekir, A. ......................................... 31, 76 Belch, J.J.F. ........................................ 64 Beleslin, B. .......................................... 98 Belgacem, O. ...................................... 76 Belhabib, M. .................................. 31, 76 Béliard, S. ........................................... 81 Bellibas, S.E. ...................................... 73 Belloc, I................................................ 28 Belomestnov, P. ................................. 87 Bełtowski, J. ........................................ 41 Ben, Abdelaziz, A. ............... 83, 92, 104 Ben, Belkacem, K. ........................... 105 Ben, Hamda, K. .................... 76, 85, 126 Ben, Hassine, F................................ 103 Ben, Khalfallah, A. ..................... 79, 119 Ben, Rejeb, N. ...................... 83, 92, 104 Benaiges, D. ............................. 109, 110 Benazzoug, Y. .................................. 119 Bencová, S. ........................................ 94 Bender, E.A. ..................................... 123 Benetos, G. ........................................ 38 Benghozi, R........................................ 77 Bengrid, T. .......................................... 97 Benlian, P. .......................................... 80 Benn, M. .............................. 7, 32, 40, 54 Bennia, S. ........................................... 60 Bensadoun, A. ................................... 10 Beraia, E. ............................................ 56 Beraia, M. ........................................... 56 Berbée, J. ........................................... 65 Berbée, J.F.P. .................................... 68 Berdeaux, O. .................................... 122 Berendschot, T.T.J.M. .................... 118 Berenjy, S. ........................................ 104 Berenson, G.S. .............................. 7, 32 Berezin, A.E. ...................................... 56 Berge, E. ............................................. 52 Berge, K.E. ......................................... 50 Berge, R.K. ......................................... 86 Berger, J.M. .......................................... 6 Bergström, G...................................... 53 Berguete, S. ....................................... 79 Berliner, S......................................... 105 Bermudez, G. ..................................... 40 Bernardi, F.......................................... 60 Bernaschi, M. ..................................... 99 Bernini, F. ........................................... 71 Bernini, S.K. ..................................... 127 Berrougui, H. ...................................... 42 Berthet, B.......................................... 101 Berti, S. ..................................61, 93, 108 Bertolami, A.................................. 76, 96 Bertolami, M.C. ............................ 76, 96 Bertolotto, M. ...................................... 47 Bertoncelli, A. ..................................... 64 Bertoni, S. ........................................... 68 Bertsch, T. .........................116, 127, 128 Berzina, M. ....................................... 107 Besseling, J. ................................. 26, 51 Betriu, À. ............................................. 54 Bevilacqua, S. .................................... 93 Beygui, F. ............................................. 8 Beylot, M. ............................................ 74 132 Bhandari, U. ...................................... 109 Bianchi, G. .......................................... 93 Bianchini, F.J. ..................................... 93 Bianco, H.T. ................................ 85, 101 Bieghs, V. ................................ 16, 22, 71 Bielolus, -, Wilk, A. ........................... 116 Bilcikova, E. ........................................ 87 Billon, C. .............................................. 69 Billon-Gales, A. .................................. 29 Billotte, S. ............................................ 87 Binder, C. ............................................ 21 Binder, C.J. ......................................... 41 Binder, Christoph ............................... 21 Bisoendial, R.J. .................................. 27 Bispo, D.L. .................................... 71, 72 Bisserier, M. ........................................ 37 Bisson, M. ........................................... 99 Bitsis, T................................................ 82 Bittar, R. .................... 30, 70, 75, 79, 103 Bittar, R.K............................................ 82 Björkbacka, H. .................................... 18 Bjørndal, B. ......................................... 86 Blaak, E. .............................................. 36 Blache, D. ........................................... 27 Blaha, M. ..................................... 81, 112 Blaha, V. .............................. 81, 110, 112 Blaise, S. ....................................... 52, 61 Blanco, G. ........................................... 58 Blanco-Colio, L.M. ............................. 41 Blanco-Vaca, F............................. 10, 33 Blankenberg, S............................. 8, 117 Blé-Castillo, J.L. ................................. 90 Bleda, Moreno, S. ............................ 100 Bleda, S. .................................. 65, 68, 94 Blirando, K. ......................................... 60 Bloedon, L.T. ...................................... 81 Blom, D.......................................... 23, 44 Blom, D.J. ........................................... 81 Blomberg, B.A. ................................... 45 Bobcikova, P..................................... 112 Bobescu, E. ................................ 92, 127 Bobik, A. .............................................. 18 Bobryshev, Y.V. ................... 70, 71, 100 Boby, C................................................ 43 Boccara, F............................. 52, 83, 100 Bochaton-Piallat, M.-L. ............... 59, 60 Bochem, A. ......................................... 42 Boddi, M. ...................................... 70, 95 Boehm, B.O........................................ 77 Boeing, H. ........................................... 32 Bogachev, O. ..................................... 30 Böhm, B.O. ....................................... 101 Boileau, C. .................................... 26, 50 Bolbos, R. ........................................... 64 Boldrini, B. .......................................... 20 Bombo, R............................................ 30 Bonacina, F. ................................. 33, 34 Bond, M. ............................................. 59 Bondarenko, S.A. .............................. 67 Bonde, Y. ............................................ 83 Bongard, V. ...........................77, 85, 105 Boni, F................................................. 97 Bonnefont, Rousselot, D. ........... 75, 79 Bonnefont-Rousselot, D.30, 50, 70, 103 Bonnet, F. ........................................... 35 Bonnet, J. ........................................... 84 Bonnet, Jacques ................................ 25 Bono, J.O.................................... 96, 102 Boren, J. ............................................. 16 Borén, J. ............................................. 53 Boren, Jan .......................................... 28 Borodachev, E.N. .............................. 70 Borràs, M. ........................................... 54 Borucka, J. ......................................... 62 Boshtam, M. ....................................... 70 Bosi, E............................................... 121 Bosisio, R. .......................................... 96 Bot, I. ................................................... 41 Botnar, R. ........................................... 98 Botnar, R.M. ....................................... 58 Bottazzi, B. ......................................... 34 Bøttcher, M. ........................................ 95 Botto, N. ............................................ 108 Bouacida, L. ............................... 92, 104 Bouchaert, E. ..................................... 28 Bouchard, P. ...................................... 64 Bouchareychas, L. ............................ 67 Boudys, L............................................ 81 Boue, S. ............................................ 117 Boughzala, E...................................... 83 133 Bouillet, B. ........................................... 27 Bouloumié, A. ..................................... 49 Boumaiza, I. .......................... 83, 92, 104 Bourbon, M. ........................................ 81 Bourghardt-Fagman, J. ..................... 69 Bouslama, A. ........................ 83, 92, 104 Boussel, L. .......................................... 46 Boussetta, T. ...................................... 65 Bouzourene, K. .................................. 17 Boytsov, S. .......................................... 91 Bozon, D. ............................................ 82 Bozzetto, L. ......................................... 43 Braamskamp, M. ................................ 81 Bracho, M. ........................................... 40 Brady, A.J. .......................................... 17 Brady, Adrian JB ................................ 17 Brady, I. ............................................... 36 Brandão, S.A. ................................... 101 Brattelid, T........................................... 86 Braunersreuther, V. ........................... 48 Breuer, O. ........................................... 83 Briand, O. ............................................ 74 Brianezi, L. ........................................ 115 Bricca, G. .............................. 60, 63, 101 Bridges, I. ............................................ 77 Brindisi, M.-C. ................................... 104 Brinton, E.A......................................... 33 Brites, F. ............................................ 108 Brito, Filho, S.B.D. ................... 126, 127 Brito, V........................................... 38, 68 Brockmann, E.-C................................ 72 Broisat, A. ........................................... 99 Brokopp, C. ......................................... 47 Brøndum-Jacobsen, P. ............... 40, 54 Broniec, A. .......................................... 57 Brouri, M............................ 104, 105, 115 Brouwers, M. ...................................... 50 Broyer, M. ........................................... 74 Brucker, E. .......................................... 79 Bruckert, E. .....3, 15, 30, 50, 70, 81, 103, 121, 123 Bruckert, Eric ...................................... 20 Brudi, P.......................................... 85, 86 Brufau, G. ............................................ 30 Brun, C. ............................................... 59 Brunet, A............................................. 87 Brunner, S. ......................................... 87 Brusberg, M........................................ 35 Bruyndonckx, L. ............................... 104 Bublikov, D. ...................................... 107 Bubnova, M.G. ................................. 108 Budkhashvili, M. ................................ 78 Buerke, M. .......................................... 64 Buijsse, B............................................ 32 Bulas, J. .............................................. 79 Bulatova, E.R. .................................... 78 Bulgarelli, A. ....................................... 68 Burcelin, R. ................................... 49, 75 Burnett, J.R. ....................................... 82 Burns, T.L. ............................................ 7 Burokienė, N. ................................... 118 Bursill, C. ............................................ 42 Buscato, M. ........................................ 37 Busch, M. ............................................ 47 Busnelli, M. .... 33, 35, 58, 62, 63, 86, 126 Butoi, E. .............................................. 41 Byrkjeland, R.................................... 116 C Cabeza, Letrán, L. ..................... 92, 109 Cabeza-Letran, M.L. ....................... 121 Cabou, C. ........................................... 75 Cabré, A. ............................................ 36 Cagliero, P.................................. 81, 120 Cain, V.A. ........................................... 44 Cakmak, H.A. ............................... 59, 94 Cakmak, S. ......................................... 46 Cal, R. ................................................... 6 Calabresi, L. ................................. 58, 73 Calanca, I.V........................................ 78 Calandra, S. ....................................... 26 Calandra, Sebastiano ......................... 5 Caligiuri, G.................................... 21, 38 Calin, M............................................... 41 Calzada, C.......................................... 34 Camaré, C. ......................................... 38 Cambien, F..............................8, 15, 117 Çamkıran, V. ...................................... 89 Camont, L. .............................42, 72, 108 134 Camponova, P. .................................. 42 Can, G. ................................................ 94 Canaple, L. ......................................... 69 Canário-Almeida, F............................ 92 Canet-Soulas, E. ................................ 64 Canizales-Quinteros, S. .................... 99 Canonne-Hergaux, F. ........................ 52 Cantero, X. .......................................... 80 Cantor, H. ............................................ 38 Cao, A.................................................. 18 Cao, G. .................................................. 6 Capeau, J.................................. 100, 102 Capel, E. ........................................... 100 Cappelli, S. ......................................... 61 Caraballo, R........................................ 10 Carillon, J. ......................................... 118 Cariou, B. .......................... 6, 44, 76, 102 Carlsson, M......................................... 53 Carlzon, D. ............................................ 7 Caro, N. ..................................... 109, 121 Caron-Debarle, M. ..................... 83, 100 Caron-Houde, S. .............................. 105 Carreau, V. ................................... 50, 81 Carrera, M.J. ..................................... 110 Carretta, R. ......................................... 35 Carrié, A. ................... 50, 79, 81, 82, 113 Carrilho, A. ........................................ 109 Cartland, S. ......................................... 11 Cartland, S.P. ..................................... 42 Cartocci, G. ......................................... 97 Carvalho, L.S. ..................................... 71 Casagrande, M.L. ............................ 115 Casasnovas, J.A. ............................... 84 Casella-Filho, A. ......................... 72, 115 Caslake, M. ................................... 31, 76 Casola, C. ......................................... 100 Caspar, Bauguil, S. .......................... 117 Casquero, Dominguez, S. .......... 97, 98 Cassol, A. ............................................ 78 Cassorla, G. ........................................ 65 Castagné, R.......................................... 8 Castaing-Berthou, A. ......................... 52 Castellano, J. ........................................ 6 Castell-Rodríguez, A.E. .................... 90 Castelnuovo, S. .................................. 96 Castiñeiras-Landeira, M.I. ................ 57 Catakoglu, A.B. ................................ 126 Catalan, M. ....................................... 126 Catalano, C. ....................................... 97 Catalano, G. ....................................... 63 Cataneo, L. ......................................... 40 Catapano, A. ...................................... 85 Catapano, A.L.2, 3, 4, 13, 33, 34, 37, 52, 62, 67, 68, 94, 112 Catapano, Alberico L. ........ 2, 3, 4, 5, 13 Catharino, R.R. .................................. 90 Caulfield, M.J. .................................. 124 Caussy, C. .......................................... 31 Cavalcante, M.F. ............................. 123 Cavarape, A. .................................... 115 Cecchettini, A. .................................... 62 Cefalù, A.B. ........................................ 51 Celebi, H. .......................................... 126 Cerda, A. ............................................ 85 Cerillo, A. ............................................ 61 Cerutti, C. ................................... 63, 101 Cesana, F. ........................................ 110 Ceska, R. ............................................ 99 Cha, J.-J. ............................................ 70 Cha, K.S. .......................................... 111 Chaaba, R. ..........................85, 101, 126 Chaabane, C. ..................................... 59 Chacin, L. ........................................... 40 Chagas, A.C.P. ................................ 115 Chahed, H. ................................... 31, 76 Chahine, M.N. .................................... 60 Chai, F. ............................................. 116 Chaichana, T...................................... 60 Chaignot, C. ....................................... 32 Chakraborty, M. ................................... 6 Challa, A. .................................... 88, 104 Chalmers, N. ...................................... 18 Chan, C....................................... 91, 114 Chan, D.C................................... 22, 103 Chan, T. .............................................. 46 Chandrakala, A.N. ............................. 65 Chang, C.-J. ....................................... 91 Chang, S.-F. ....................................... 69 Chang, S.G. ..................................... 112 Chang, Y.-C. ...................................... 71 135 Changarotti, J. .................................. 119 Channon, K.M. ................................. 112 Chantepie, S. ...................... 72, 103, 108 Chantzichristos, V. ............................. 57 Chao, T.-H. ......................................... 29 Chapman, J.M. ................................. 108 Chapman, M John ......................... 2, 25 Chapman, M.J. ...... 2, 13, 22, 42, 72, 90, 103, 121 Chapouly, C. ....................................... 28 Charles, A.-L............................... 34, 113 Charlton-Menys, V. .................... 72, 125 Charnaux, N. ...................................... 57 Charniot, J.-C. .............................. 75, 79 Charniot, J.-P. .................................... 75 Charradi, K.......... 79, 103, 119, 120, 121 Charriere, S. ....................................... 82 Charrière, S. ........................... 31, 74, 82 Chatelais, M. ....................................... 51 Chaturvedi, N. .................. 49, 78, 89, 95 Chatzizisis, Y. ....................................... 5 Chaudhari, H.S................................. 109 Chaudhari, S.M. ................................. 47 Chauveau, F. ...................................... 64 Chavan, S. .......................................... 72 Chebli, S............................................ 112 Chelombitko, M. ................................. 66 Chelombitko, M.A. ............................. 67 Chen, C.-C. ......................................... 46 Chen, H. .............................................. 52 Chen, I.-C............................................ 29 Chen, J.-H. .................................. 29, 113 Chen, J.-Y. ................................ 103, 114 Chen, P. .............................................. 65 Chen, S. .............................................. 56 Chen, Y. ................................ 29, 40, 123 Chen, Y.-R. ....................................... 100 Cheng, Y.-J. ...................................... 125 Cherfils, C. .................................... 70, 75 Chernova, E........................................ 72 Chernushevich, O.I. ........................... 79 Chernyavskiy, A. ........................ 91, 127 Cheta, I. ............................................. 107 Chi, Y. .................................................. 33 Chia, Y.C. .................................. 111, 112 Chiang, A. ........................................... 71 Chiappetta, C. .............................. 28, 67 Chiappino, D. ..................................... 61 Chiara, M. ..................................... 62, 63 Chicheva-Ivanova, M.M. ................. 100 Chien, M. ............................................ 18 Chien, Y.-S. ........................................ 71 Chiesa, G....... 33, 35, 58, 62, 63, 86, 126 Chiharu, N. ......................................... 56 Chiheb, S. ......................................... 105 Chillarón, J.J. ........................... 109, 110 Chin-Dusting, J. ................................. 27 Chinetti-Gbaguidi, G. ........................ 67 Ching, S. ........................................... 112 Ching, S.M........................................ 111 Chiosso, R. ................................. 96, 102 Chiou, H.-Y. ...................................... 100 Chlopicki, S. ............................... 89, 121 Chłopicki, S. ............................... 57, 106 Chmielewska, M. ............................... 38 Chmilewsky, F. .................................. 57 Cho, K.-H. ............................73, 117, 119 Cho, M.-C. .................................. 32, 103 Cho, T.-H. ........................................... 46 Choi, B. ............................................... 36 Choi, C. ............................................... 36 Choi, C.U. ........................ 36, 53, 63, 122 Choi, D.-J...................................... 32, 43 Choi, E.K. ........................................... 66 Choi, E.-Y. .................................... 70, 76 Choi, I.S. ............................................. 95 Choi, J.H. .......................................... 111 Choi, J.Y. .......................................... 112 Choi, S.H. ........................................... 49 Choi, Y.H. ................................... 98, 112 Choquet, P. ...................................... 113 Choqueux, C. ..................................... 62 Chou, C.-H. .............................. 103, 114 Choudhury, R.P. .............................. 112 Christensen, G. ................................ 113 Christoffersen, B.Ø. .......................... 95 Chroni, A............................................. 71 Chu, P.-H. ..................................... 29, 91 Chugunova, Y. ................................. 118 Chukkapalli, S. ................................... 63 136 Chumakova, G. 100, 102, 103, 118, 125 Chung, H. ............................................ 76 Chung, I.-M. ........................................ 43 Chung, W.J. ...................................... 102 Chung, W.-Y. ...................................... 78 Cicek, M. ........................................... 109 Cicha, I. ............................................... 68 Cifkova, R. .................................... 40, 96 Cinquanta, P. ...................................... 58 Ciociola, E. .......................................... 31 Cioni, G. ........................................ 70, 95 Cipollone, F......................................... 90 Cipriano, P. ......................................... 43 Cirovic, S. .......................................... 119 Citti, L. ................................................. 62 Civeira, F. ............................................ 84 Clara, F................................................ 58 Claude, S. ........................................... 43 Clavey, V. ............................................ 74 Clement, K. ................................... 30, 70 Clement, M. ........................................ 38 Clément, N. ......................................... 60 Clerico, A. ......................................... 108 Cochran, B.J. ...................................... 27 Cocozza, S. ........................................ 43 Coelho, O.R. ....................................... 78 Coen, M. .............................................. 60 Cofán, M.............................................. 84 Cohen, A. ...................................... 52, 83 Cohen, M. ......................................... 105 Cohen, R. .......................................... 116 Cokkinos, D.V..................................... 84 Coletta, P. ........................................... 31 Colhoun, H. ......................................... 36 Colin, S. ............................................... 74 Collet, X. .............................................. 75 Collet, Xavier ...................................... 27 Colletes, J.H.G. .................................. 83 Colom, A. ............................................ 75 Colombo, C. ...................................... 110 Combescure, C. ................................. 47 Comte, B. .......................................... 122 Condorelli, G....................................... 37 Çoner, A. ..................................... 89, 107 Conraads, V...................................... 104 Conradie, K.R. ................................... 85 Conte, F. ............................................. 43 Conti, B. .............................................. 16 Contini, A. ......................................... 127 Contreras-Duarte, S. ......................... 34 Cooney, J. .................................... 31, 76 Cooper, S. .......................................... 56 Copin, C. ............................................. 67 Copponi, G. ................................ 40, 107 Corbier, C. ........................................ 106 Corral, P. ............................................ 58 Corrales, D. ................................ 92, 121 Correa, M............................................ 60 Correig, X. .......................................... 36 Corsini, A. ................ 37, 62, 94, 125, 127 Corti, R. ............................................... 47 Corvera-Tindel, T. ........................... 111 Cosentino, N. ............................. 40, 107 Coskun, A.U. ................................ 29, 55 Cosson, C........................................... 75 Cosson, E. ................................ 105, 110 Costa, L. ............................................. 52 Costa, S. ............................................. 71 Costabile, G. ...................................... 43 Costagliola, D. ............................. 52, 83 Costaz, C. ........................................... 74 Costet, P. ........................... 6, 37, 76, 102 Cotoi, O............................................... 18 Cottin, Y. ....................................... 53, 58 Couraud, P.O. .................................... 34 Courtier, A. ......................................... 47 Coutureau, T. ................................... 121 Couvert, P. ..............................70, 79, 82 Covaciu, A. ................................. 92, 127 Covas, M.I. ......................................... 35 Cozma, A. ......................................... 104 Crea, F. ....................................5, 40, 107 Crisci, I. ............................................... 51 Cristol, J.-P....................................... 118 Crociati, L. ........................................ 100 Croft, K. ............................................. 119 Cruz, Ferreira, R. ............................... 53 Cuchel, M. ...................................... 3, 81 Cudejko, C.......................................... 28 Cuesta, Torres, L.F. .......................... 27 137 Cuniberti, L. ........................................ 82 Cutrin, J.C. ........................................ 119 Cutuli, L. ........................................ 33, 34 Czarnecka, D. ................................... 127 Czyzynska, I. .............................. 89, 121 de, Faria, E.C. ................. 71, 78, 83, 128 De, Gendt, K. ..................................... 69 De, Haro, J. .............................65, 68, 94 de, Haro, Miralles, J. ....................... 100 De, Henauw, S..................................... 7 de, Jager, S.C.A. ......................... 41, 61 de, Jong, R.C.M........................... 18, 47 de, Leite, Jr, A.C. ............................. 115 de, Leon, H....................................... 117 De, Lonlay, P. .................................... 80 De, Nardis, V...................................... 90 de, Oliveira, Izar, M.C. ...................... 85 De, Oliveira, S.................................... 95 De, Paoli, F. ....................................... 67 De, Pellegrin, A.................................. 86 De, Smet, E. ....................................... 30 de, Smet, E.D. ................................... 22 De, Vos, W. ........................................ 36 De, Vries, M.R. ................. 18, 41, 47, 61 de, Winther, M. .................................. 67 De, Winther, M. .................................. 18 Deanfield, J.E. ................................... 13 Debelle, L. .......................................... 61 Deblache, T. ....................................... 75 deBlois, D. .......................................... 68 Deckert, V........................................... 76 deFaire, U........................................... 36 Defesche, J. ....................................... 51 Defesche, J.C. ............................. 26, 51 Dejouvencel, T. .................................. 48 Del, Ben, M. ....................................... 84 Del, Castillo, D. .................................. 74 Del, Porto, F. ...........................28, 62, 67 Del, Turco, S. ..................................... 59 Del, Valle, R. .............................. 96, 102 Delatour, V. ........................................ 79 Delay, M. ............................................ 74 Delbosc, S. ............ 34, 38, 48, 57, 64, 73 Delcore, M.G. ..................................... 43 Delgado, L. ......................................... 38 Della, Corte, G. .................................. 43 della, Latta, D. .................................... 61 Della, Pepa, G. .................................. 43 Della, Rocca, C............................ 28, 67 Dellepiane, A.................................... 108 D Da, Porto, A. ..................................... 115 Dadamyants, N. ................................. 96 Dadamyants, N.G. ............................. 88 D'Agostino, M.N. ................................ 51 Dahlbom, I. ......................................... 18 Dalamaga, M. ..................................... 93 Dalla-Riva, J. ...................................... 73 Dallegri, F............................................ 47 Dallinga-Thie, G. .......................... 10, 36 Dallinga-Thie, G.M. ...................... 51, 55 Dallinga-Thie, Geesje ........................ 22 Dallongeville, J. ................................ 123 Damaskos, D. ..................................... 84 Damelou, A. ...................................... 114 Damonte, E. ........................................ 77 Dang, B.Q. .................................... 34, 56 D'Angelo, A. ........................................ 51 Daniels, S.R.......................................... 7 Daniil, G. ............................................. 71 Dart, A.M. ............................................ 27 Das, S. ................................................. 75 Dashkova, A. .................................... 100 Daugareil, C...................................... 117 Davey-Smith, G. ................................... 7 Davids, J. ............................................ 52 Davidson, W.S. .................................. 72 Davies, A.H. ........................................ 63 Davlouros, P. .................................... 114 Day, W.W. ......................................... 101 D'Cruz, D............................................. 98 De, Blasis, G....................................... 90 de, Boer, J.F. ................................ 49, 72 de, Bruin, R.G....................................... 8 De, Castro-Orós, I.............................. 84 De, Caterina, A.R............................. 108 de, Craen, A.J.M. ............................... 88 de, Faire, U. ...................................... 124 138 Dellera, F. ......................................... 126 Dementjeva, N. ........................ 107, 110 Demougeot, C. ................................. 122 den, Hartog, G. ................................... 74 Dencker, M. ...................................... 116 Deniset, J.F......................................... 60 Denisova, D. ....................................... 79 Dent, R. ............................................... 44 Denyanets, S. ................................... 114 D'Erasmo, L. ....................................... 84 Derex, L. .............................................. 46 Descamps, O. ............................. 85, 121 Desgranges, C. .................................. 28 Desideri, G. ......................................... 90 Desilles, J.P. ....................................... 34 Devillers, M. .................................. 26, 50 Devlin, J.J. .......................................... 88 Devold, H. ......................................... 122 Dhaouadi, N........................................ 63 Dhar, K. ............................................... 51 Dhenain, M. ........................................ 64 Di, Bartolo, B. ......................... 11, 37, 42 Di, Bartolo, B.A................................... 38 Di, Costanzo, A. ................................. 84 Di, Filippo, M........................... 31, 74, 82 di, Gioia, C. ................................... 28, 67 di, Giuseppe, R. ................................. 32 Di, Leo, E. ........................................... 51 Di, Marino, L. ...................................... 43 Di, Taranto, M.D. ................................ 51 Diallo, D. ............................ 48, 56, 57, 73 Diani, E. ............................................... 67 Dias, N.V. ............................................ 75 Diaz, O. ............................................... 66 Diaz-Zagoya, J.C. .............................. 90 Dibrov, E. ............................................ 60 DiCioccio, T. ....................................... 87 Diczfalusy, U....................................... 74 Diederichsen, A.C.P. ......................... 45 Dierke, J. ............................................. 32 Dietel, B. .............................................. 68 Di-Filippo, M. ...................................... 82 Dijkstra, M. .......................................... 31 Dikkers, A............................................ 49 Dikur, O. .............................................. 39 Diniz, G.M. ........................................ 116 Dionyssiou-Asteriou, A. .................... 93 Djalalov, F. ......................................... 88 Djekic, D. ............................................ 92 Dlouha, D............................................ 99 Dmitrieva, O. ...................................... 87 Dobordzhginidze, L. .......................... 40 Dobrcucki, L.W. ................................. 57 Dobreanu, D. ...................................... 92 Dobrucki, I.T. ...................................... 57 Doddapattar, P................................. 124 Doering, L.V. .................................... 111 Doi, M. ................................................. 93 Dolan, S. ........................................... 106 Dollet, L............................................. 102 Domagala, Z.A. ................................ 116 Domei, T. ............................................ 29 Domeij, H. ........................................... 63 Domenig, C. ..................................... 114 Domitrz, K........................................... 73 Dong, J. .............................................. 73 Dorea, E.L. ......................................... 85 Dorighello, G.G. ............................... 101 Doroszko, A...................................... 126 Dörr, M. ............................................. 110 dos, Santos, J.C. ......................... 71, 72 Douek, P.-C........................................ 46 Doulamis, I. ...................................... 119 Dourado, P.M. .................................. 115 Drahun, A. .................................. 89, 121 Drake, I. .............................................. 17 Drakopoulou, M. .......................... 38, 45 Drandarov, K. ..................................... 98 Drapkina, O.M. ................................... 88 Drechsler, C. .................................... 101 Drexel, H. .......................................... 102 Driss, F. .............................................. 65 Dritsa, V. ..................................... 97, 104 Drogari, E. .......................................... 81 Dronca, M. ........................................ 106 Drosos, A.A. ............................. 106, 126 Drożdż, K.M. ...................................... 38 Du, Plessis, A.M. ............................... 81 Duaip, G. ............................................ 82 Duan, Z. ............................................ 124 139 Dubois, N. ......................................... 101 Dubray, C. ......................................... 107 Duca, L. ......................................... 52, 61 Duchateau, G.S.M.J.E. ..................... 43 Duchêne, E. ........................................ 81 Ducimetiere, P. ................................... 54 Dudek, K. .......................................... 114 Dukat, A. ................................... 108, 115 Dukát, A. ............................................. 79 Dulak, M.G. ......................................... 60 Dullaart, R. .......................................... 72 Dullaart, R.P. ...................................... 72 Dullaart, R.P.F. ................................... 49 Dumitriu, I.E. ....................................... 11 Dumont, S. .......................................... 82 Dunér, P. ............................................. 18 Dunn, L. ............................................... 42 Duran, M.C. ...................................... 121 Durán, M.C. ................................ 92, 109 Durand, T. ......................................... 122 Durante, C. ......................................... 31 Durlach, V. .......................................... 61 Durlach, Vincent ................................. 26 Dutra-Rodrigues, M.S. ...................... 78 Duvillard, L. ................................. 27, 104 Dwyer, T. ......................................... 7, 32 Dzięgiel, P. .......................................... 38 Dzingalasevic, G. ............................... 94 Eisenhofer, G. .................................... 40 Eklund, C. ........................................... 96 Ekmekci, H. ........................................ 59 Ekmekci, O.B. .................................... 59 Ekroos, K. ........................................... 35 El, Khoury, P. ............................... 30, 63 Elbaz, M. ............................................. 85 Eldor, R. ............................................ 108 Elens, L. .............................................. 81 Elia, L. ................................................. 37 Elias, J.J. ............................................ 95 Elikomov, V. ..................................... 125 Elisaf, M. ..................................... 88, 104 Elisaf, M.S. ................................... 76, 86 El-Menyar, A. ....................110, 114, 115 Elofsson, M. ....................................... 10 Elonen, N. ........................................... 72 Elvevoll, E......................................... 122 Elvevoll, E.O. ................................... 122 Emoto, N............................................. 11 Empana, J.-P. .................................... 54 Empen, K. ......................................... 110 Endo, K. ....................... 31, 109, 111, 123 Endo, T. .............................................. 62 Endoh, H............................................. 32 Enomoto, M. ..................................... 121 Enquist, P.-A. ..................................... 10 Entz, L. .............................................. 127 Ercan, M.G. ...................................... 126 Erdmann, J. ........................................ 68 Eren, M. .............................................. 94 Erer, B. ................................................ 94 Ergang, P............................................ 64 Ergen, A. ............................................. 83 Erglis, A. ................................... 107, 125 Ergur, B.U........................................... 69 Ericson, U. .............................17, 39, 101 Ericsson, M. ....................................... 75 Eriksson, J. ......................................... 33 Eriksson, M. ............................10, 31, 44 Eriksson, U. ........................................ 31 Erlinge, D. ........................................... 22 Ernerudh, J................................... 66, 67 Escolà-Gil, J.C. .................................. 33 Esparza, Gómez, L. ........................ 100 E Easton, R. ......................................... 123 Eastwood, S. ...................................... 49 Eatough, R. ................................. 72, 125 Ebelt, H................................................ 64 Ebina, Y. ............................................ 118 Eck, P. ............................................... 123 Edfeldt, K. ........................................... 66 Edjlalipour, M. ..................................... 87 Edsfeldt, A. ................................. 75, 110 Edvardsen, E. ................................... 116 Eeckhoute, J. ...................................... 67 Egido, J. .............................................. 41 Ehnholm, C. ............................ 10, 33, 48 Eilertsen, K.-E. ................................. 122 140 Esparza, L. .................................... 68, 94 Espinosa, González, M.C. .............. 117 Esquirol, Y. ....................................... 105 Esquivel, C.................................. 96, 102 Esteller, M. .......................................... 74 Estruch, R. .......................................... 35 Etxebarria, A. ...................................... 80 Euthimiou, V. .................................... 120 Evaldson, C. ....................................... 67 Evans, I. .............................................. 59 Ewing, M.M. ...................... 18, 41, 47, 61 Extebarria, A. ...................................... 81 Ezhov, M. ...................................... 86, 87 Feinstein, S.B. ................................... 28 Feinstein, Steven B. .......................... 28 Feldman, C.L. .............................. 29, 55 Felekos, I. ........................................... 38 Felix, S.B. ......................................... 110 Ferchaud, Roucher, V. ................... 122 Ferchaud-Rouchet, V........................ 95 Ferchichi, S. ................................. 31, 76 Ferin, R. .............................................. 91 Fernandes, C.R. ................................ 95 Fernandes, M. .................................... 92 Fernández, E. .............................. 38, 54 Fernandez, I. .................................... 119 Fernandez, Quero, M.................. 97, 98 Fernández-Laso, V. .......................... 41 Fernández-Marrero, Y. ..................... 38 Ferrannini, E. ............................... 20, 35 Ferré, R....................................... 17, 102 Ferreira, E.B. ............................ 126, 127 Ferreira, F........................................... 92 Ferreira, R. ....................................... 116 Ferri, L......................................28, 62, 67 Ferri, N. .......................... 37, 94, 125, 127 Ferrieres, J. ................................ 54, 105 Ferrières, J. .............................77, 81, 85 Ferronato, S. ...........................64, 65, 67 Ferruelo, A.......................................... 94 Fesel-Fouquier, V. ............................. 70 Feugier, P. .................................. 63, 101 Feuillet, F. ........................................... 76 Feve, B. ............................................ 102 Fidan, Y. ........................................... 121 Filip, G................................................. 61 Filip, M. ............................................. 116 Filip, S. .............................................. 112 Filipovsky, J.................................. 40, 96 Filippatos, T.D.................................... 76 Fink, G. ............................................. 116 Finsen, A.V....................................... 113 Fiol, M. ................................................ 35 Fiorelli, S............................................. 33 Fischer, S. .......................................... 86 Fisher, E.A.................................... 11, 37 Fisher, J. ............................................. 94 Fiskesund, R. ..................................... 47 F Fabre, A. ............................................. 49 Fabre, J.-E. ................................. 34, 113 Fabris, B. ............................................. 35 Fabryova, L. ...................................... 108 Fagret, D. ............................................ 99 Fajardo, C.M. ...................................... 85 Falchi, A.G. ....................................... 101 Falcioni, E. ........................................ 107 Falcón, V. ............................................ 38 Fallanca, A. ....................................... 110 Faludi, A.A. ................................... 76, 96 Fan, J........................................... 29, 123 Fang, L. ............................................... 27 Fantozzi, C.............................. 28, 62, 67 Farnier, M. ..................... 9, 13, 81, 85, 86 Farnier, Michel...................................... 9 Fartushna, O.Y. ................................ 108 Fatoki, J.O......................................... 120 Faure, P. ........................................... 122 Favari, E. ............................................. 71 Fechner, A. ....................................... 120 Federspiel, M.-C. ............................... 70 Fedi, S. ................................................ 70 Fedorowicz, A............................. 57, 106 Fedoseeva, L.S. ................................. 78 Fehérvári, M. .................................... 127 Feidt, C. ............................................. 106 Feig, J.E. ............................................. 37 Feillet, F. ............................................. 80 141 Fjornes, T. ........................................... 92 Flegar-Meštrić, Z. ............................. 115 Fletcher, J. .......................................... 65 Florentin, M. ........................................ 86 Flores, Le-Roux, J.A................ 109, 110 Flouriot, G. .................................... 29, 37 Fobker, M. ........................................... 76 Fogelstrand, L. ................................... 41 Fogelstrand, P. ................................... 69 Fonseca, F.A. ....................... 43, 85, 101 Fonseca, H.A. ................................... 101 Fontaine, C. .................................. 29, 37 Foody, J. ............................................. 85 Ford, I. ................................................. 88 Forgues, P. ................................... 44, 87 Forrest, C. ......................................... 124 Fortun, M. ............................................ 92 Fortunato, G. ...................................... 51 Foscarini, J.M. ............................ 96, 102 Fotopoulos, A. .................................. 106 Fouchier, S.W............................... 26, 51 Fouquier, V.F. ..................................... 82 Fourcade, J. ........................................ 77 Fournier, N. ......................................... 30 Fracassi, F. ......................................... 40 Fraga, A. ............................................. 38 França, C.N. ....................................... 85 France, M. ................................... 72, 125 Franceschini, G. ................................. 58 Franceschini, S.A............................... 93 Franckx, H......................................... 104 Franco, S. ........................................... 60 Franczyk-Zarow, M. ......................... 121 Franczyk-Zarow, M.A. ....................... 89 Franzosi, M.G. .................................. 100 Fredenrich, A. ..................................... 81 Freeman, L. ........................................ 22 Freyer, J. ............................................. 68 Friand, V.............................................. 57 Frias, M. .............................................. 48 Friberg, P. ........................................... 40 Frikke-Schmidt, R. ............................. 84 Frisdal, E. ...................................... 30, 74 Froemming, G.R.A. .................... 66, 120 Frostegård, A. ....................... 47, 63, 124 Frostegård, J. ........................47, 63, 124 Fu, H. .................................................. 64 Fu, Y. ................................................... 27 Fuenffinger, N. ................................... 32 Fuentes, S. ......................................... 36 Fuentes-Prior, P. ............................... 10 Fuertes, N........................................... 44 Fujioka, N. .......................................... 45 Fujioka, T. ......................................... 111 Fujishima, Y. .................................... 111 Fujita, Y................................................. 6 Fujiyoshi, A................................... 91, 95 Fukami, A. ........................................ 121 Fukuda, A. ........................................ 123 Fukunaga, H. ..................................... 58 Fülöp, P. ............................................. 95 Fumagalli, H.F. .................................. 93 Funck-Brentano, C. ........................... 52 Fundinho, C...................................... 116 Furukawa, T. ...................................... 58 Furuyama, S. ................................... 108 Futema, M. ......................................... 80 Fysekidis, M. ............................ 105, 110 G Gaál, K. ............................................... 72 Gabriel, S............................................ 50 Gadeau, A.P. ..................................... 52 Gadeau, A.-P. .................................... 28 Gaestel, M. ......................................... 64 Gafarov, V. ....................................... 117 Gafarova, A. ..................................... 117 Gagliano, T. ........................................ 60 Gagulin, I. ......................................... 117 Gaillet, S. .......................................... 118 Gajda, M. .......................................... 121 Gajdosik, J................................ 108, 115 Gajos, G. ............................................ 39 Galabova, G. ...................................... 87 Galán-Garcia, P. ................................ 80 Galano, J.-M. ................................... 122 Galassini, A. ....................................... 70 Galchinskaya, V............................... 110 Gale, C.P. ......................................... 124 142 Galeeva, N. ....................................... 110 Gallagher, P...................................... 114 Galli, E. .............................................. 108 Gambert, P. ........................................ 58 Gämperli, O. ....................................... 47 Gan, A.M. ............................................ 41 Gan, L.-M. ........................................... 96 Gandara, A. ...................................... 125 Gandhi, H. ........................................... 78 Gandjbakhch, I. .................................. 75 Gannar, F. ......................................... 104 Ganugi, E. ........................................... 70 Ganzetti, G...................... 35, 62, 63, 126 Gapon, L. .................................. 107, 110 Garcia, Carro, J. ............................... 125 Garcia-Arguinzonis, M......................... 6 García-Sánchez, C. ........................... 77 Garelnabi, M. ............................ 116, 123 Garjani, A. ........................................... 66 Garlanda, C. ....................................... 34 Garlaschelli, K. ........................... 33, 112 Garlichs, C. ......................................... 68 Garmy-Susini, B. ................................ 38 Garnotel, R. ........................................ 52 Garofaro, A. ........................................ 76 Garon, A. ............................................. 82 Garrido, Zambrano, E.C. ................ 117 Garzone, P.D. ............................... 44, 87 Gasevic, D. ......................................... 40 Gašpar, &. ........................................... 79 Gasparini, D...................................... 115 Gaston, A.-T. ...................................... 38 Gaudet, D............................................ 81 Gauthier, K.......................................... 69 Gautier, E. ..................................... 64, 67 Gautier, T. ..................................... 10, 27 Gavrilova, N.E. ................................... 79 Gayral, S. ............................................ 52 Gebauerova, M. ................................. 99 Geerling, J.J. ...................................... 16 Geiger, K. .......................................... 102 Geller-Rhomberg, S. ....................... 102 Gensini, G.F. ................................ 70, 95 Gentile, M. ........................................... 51 Geny, B. .............................................. 34 Georgiadis, I. .................................... 119 Germain, M. ......................................... 8 Gerszten, R. ....................................... 25 Geryk, L. ............................................. 94 Ghaleb, Y............................................ 50 Ghannam, M.M. ....................... 104, 120 Ghezzi, C. ........................................... 99 Ghosh, M. ........................................... 76 Ghosh, S.M. ....................................... 65 Giacco, A. ........................................... 43 Giacco, R. ........................................... 43 Giacobbe, C. ...................................... 51 Giannattasio, C. ............................... 110 Giannopoulou, V. ............................... 82 Gidlund, M. ....................................... 101 Gielen, S. ............................................ 64 Giezek, H. ........................................... 86 Giglioli, C. ........................................... 70 Gijbels, M............................................ 67 Gilabert, R. ................................. 35, 126 Gilibert, S. ........................................... 57 Gille, A. ............................................. 123 Gillott, R.G. ....................................... 124 Gilly, F.N. .............................................. 4 Gilmanov, D. ...................................... 93 Ginsberg, H. ................................... 2, 14 Giral, P. ... 22, 32, 67, 75, 81, 82, 90, 103, 113 Girard, E. ...................................... 26, 30 Girerd, X. .......................................... 113 Giridhar, R. ......................................... 78 Girish, M.P.......................................... 75 Girodo, A.M. ..................................... 116 Girona, J. ............................................ 17 Gisletun, U.......................................... 92 Giugliano, R.P.................................... 44 Giunta, G. ........................................... 82 Gizas, V. ........................................... 114 Gkrozou, F.......................................... 57 Gladine, C. ....................................... 122 Glauber, M.................................... 61, 93 Glinkina, I............................................ 97 Głodzik, J. ......................................... 116 Goday, A........................................... 110 Goeritzer, M. .................................... 124 143 Gogou, M. ......................................... 119 Gohara, S............................................ 55 Gojkovic-Bukarica, L. ...................... 119 Goldman, Rosas, L. ........................... 86 Golledge, J.......................................... 44 Golovach, I.V. ................................... 113 Golovach, S.V. ................................. 113 Gomaraschi, M. .................................. 73 Gomes, E.I.L....................................... 83 Gomez, Lira, M. ...................... 64, 65, 67 Gomez, Rosso, L. ............................ 108 Gomez-Guerrero, C. .......................... 41 Gomita, K. ........................................... 47 Gomułkiewicz, A. ............................... 38 Goncalves, I...................................... 110 Gonçalves, I........................................ 75 Gonçalves, R. ..................................... 96 Gonzaga, C................................... 76, 96 Gonzalez, A. ....................................... 40 González, C. ................................. 34, 68 González-Juanatey, J.R. .................. 57 González-Peteiro, M. ......................... 57 Gori, A.M. ...................................... 70, 95 Gori, T.................................................. 53 Gorlova, O........................................... 70 Gosukuma, M.C. ................................ 85 Götberg, M. ......................................... 22 Gottrand, F............................................ 7 Goudev, A. .......................................... 58 Goudevenos, I. ................................. 114 Goudevenos, J.A. ............................ 120 Goueffic, Y. ......................................... 95 Goujard, C. ......................................... 63 Gourdy, P. ............................... 29, 37, 49 Gower, J.D. ....................................... 124 Gracheva, E........................................ 66 Graham, A......................................... 106 Grammer, T. ....................................... 83 Grammer, T.B............................... 77, 80 Grandoso, L. ....................................... 80 Grangeot, R. ..................................... 101 Grass, D.S. ......................................... 10 Grassos, H. ......................................... 38 Gratchev, A. ........................................ 65 Gratsiansky, N. ................................... 40 Grebe, M. .......................................... 113 Grebenshchikova, I. .......................... 97 Gregersen, I. ...................................... 65 Greil, G. .............................................. 98 Grenkowitz, T. .................................... 76 Griffo, E............................................... 43 Grigore, L.................................... 33, 112 Grillo, A. .............................................. 35 Griñán, T............................................. 38 Gritsenko, O. ............................ 103, 125 Grivel, J.-C. .............................51, 61, 64 Grives, A. ............................................ 47 Grodzicki, T. ..................................... 116 Groen, B. ...................................... 30, 36 Gromova, E. ..................................... 117 Gronlund, C. ................................. 98, 99 Grova, N. .......................................... 106 Gruetter, R.......................................... 17 Grufman, H. ...................................... 110 Grundtman, C. ................................... 53 Grunenwald, E. .................................. 29 Grzegorek, I. ...................................... 38 Guaita, S............................................. 36 Guardado, J. ...................................... 92 Guardamagna, O....................... 81, 120 Guardiola, M. ..................................... 74 Guastella, G. ...................................... 60 Guedj, K. ....................................... 38, 61 Guerci, B........................................... 100 Guerin, M. .................... 26, 30, 63, 70, 74 Guermaz, R. ......................104, 105, 115 Gui, Q.-J. ............................................ 51 Guichardant, M. ................................. 65 Guichot, Y.D. ...................................... 22 Guiguet, M. ......................................... 83 Guilland, J.-C. .................................... 58 Guillaume, M. ..................................... 49 Guillaumet, A. .................................... 74 Guillerm, E.......................................... 75 Guimaraes, E.S. ................................ 85 Guisado, Rasco, A. ..................... 97, 98 Gullberg, B. ........................................ 39 Gullestad, L. ............................... 65, 113 Gumbiner, B. ................................ 44, 87 Guo, S. .............................................. 124 144 Gupta, G.K. ......................................... 43 Gupta, N. ............................................. 50 Gupta, S.K. ......................................... 75 Gurevich, V. ........................................ 78 Gurzeler, E.......................................... 31 Gustin, M.-P. ............................... 63, 101 Guterres, S.S. ................................... 123 Guyton, J.R. ........................................ 85 Guzeloglu, M. ..................................... 60 Guzik, T. ...................................... 61, 116 Guzik, T.J. ..................................... 60, 66 Gvozdyk, M. ........................................ 82 Gybernatorova, E.E. ........................ 105 Gylling, H. ......................................... 105 Hammami, S. ............................. 85, 126 Hamre, M. ........................................... 92 Hamrefors, V. ..................................... 17 Hamrour, F. .............................. 105, 115 Hamsten, A. ....................................... 36 Han, S.H. ......................... 48, 89, 95, 102 Han, X. .......................................... 33, 56 Handberg, A. ...................................... 50 Handgraaf, S. ..................................... 49 Hannou, S. ....................................... 105 Hannou, S.A. ...................................... 28 Hanotin, C. ......................................... 87 Hansel, B. ..............................32, 82, 103 Hansson, G.K. ............................. 41, 66 Hara, M. ............................................ 106 Harada-Shiba, M. .................44, 80, 106 Haraguchi, H. ..................................... 39 Haraguchi, Y. ................................... 120 Harangi, M. ............................72, 80, 102 Harith, H. ............................................ 11 Harnek, J. ........................................... 22 Harrison, G. ................................ 91, 114 Harrison, M.J...................................... 34 Harvey, D............................................ 81 Hasan, S.T. ...................................... 126 Hasballa, R......................................... 71 Hasegawa, H. .................................. 125 Hashemizadeh, H. ........................... 117 Hashimoto, T...................................... 64 Hasokawa, M. ............................ 39, 120 Hassim, N.F. ...................................... 58 Hatri, A. ..............................104, 105, 115 Haulon, S. ........................................... 67 Havekes, L.M. ................... 16, 49, 65, 71 Havinga, R.......................................... 30 Hayashi, H. ......................................... 42 Hazan, E. ............................................ 60 He, Y. .................................................. 47 Heasman, J. ................................. 49, 78 Hebert, H. ........................................... 73 Hecking, M. ........................................ 49 Hedegaard, M. ..................................... 8 Hedin, U. ............................................. 66 Hedjazi, L............................................ 76 Hedley, T.E. ....................................... 60 H Haas, B................................................ 54 Haas, G.-M. ...................... 116, 127, 128 Habalova, V. ....................................... 99 Habenicht, A. ...................................... 21 Habibinejad, H. ................................... 63 Hack-Ryoung, K. ................................ 78 Haddad, O. ......................................... 57 Hadi, N.R. ........................................... 65 Haeggström, J. ................................... 63 Hägerstrand, L. .................................. 35 Haghjooy, Javanmard, S. ................. 56 Hagiwara, N. ....................................... 47 Hahalis, G. ........................................ 114 Haidinger, M. ...................................... 49 Hajkova, J. ........................................ 112 Hakki, Kazazi, E. ................................ 46 Halici, F. ............................................ 110 Hall, A.S. ........................................... 124 Hällgren, P. ......................................... 61 Halonen, J. ........................................ 105 Haluzik, M. ........................................ 110 Halvorsen, B. ................................ 65, 80 Hama, S. ..................................... 72, 125 Hamamatsu, A. .................................. 62 Hamazaki, N. .................................... 118 Hamdis, N. ........................................ 119 Hamlat, Khennaf, N. .......................... 74 Hammami, M. ..................... 85, 101, 126 145 Heeren, J. ........................................... 31 Hegele, R.A. ....................................... 81 Heinle, H. .......................................... 119 Heinonen, S. ....................................... 31 Heinonen, S.E. ................................... 35 Heizmann, C.W. ................................. 59 Hellberg, S. ......................................... 46 Hellstrand, S. ...................................... 39 Hendrikx, T. ........................................ 22 Henein, M. ......................... 61, 97, 98, 99 Hense, H.W. ....................................... 32 Heras, M........................................ 17, 36 Herbeth, B. ........................................ 106 Hermanns, H.M. ................................. 47 Hermansson, C. ................................. 66 Hernandez, Y. .................................. 119 Herová, M. .......................................... 41 Herrera, A.M. ...................................... 60 Herreras, Z........................................ 126 Hersberger, M. ................................... 41 Heuillet, M. .......................................... 79 Heusch, G. .......................................... 37 Hewing, B............................................ 37 Heyden, M. ......................................... 53 Hidalgo, P. .......................................... 34 Hiemstra, H. ........................................ 43 Hiemstra, P.S. .................................... 65 Higaki, Y. ............................................. 54 Hildebrandt, M. ................................... 45 Hindmarch, C. .................................... 59 Hindy, G. ............................................. 17 Hirai, Y. .............................................. 121 Hirata, A. ........................................... 122 Hirata, K. ....................................... 39, 75 Hirata, K.-I. ...................... 11, 74, 75, 120 Hirata, M........................................ 56, 76 Hirata, M.H. ......................................... 85 Hirata, R.D.C. ..................................... 85 Hirawa, N. ........................................... 88 Hirche, F.............................................. 32 Hirohata, S. ......................................... 93 Hirsch, E.............................................. 52 Hisakawa, N. ...................................... 94 Hisamatsu, T. ............................... 91, 95 Hitos, K. ............................................... 65 Hjuler, Nielsen, M. ............................. 50 Hlaváčková, M. .................................. 60 Hlawaty, H. ......................................... 57 Ho, C.-S. ................................... 103, 114 Hoefler, G. ........................................ 124 Hoekstra, J. ........................................ 36 Hoekstra, M. ....................................... 42 Hoelschermann, H. ......................... 113 Hoeng, J. .......................................... 117 Hoerstrup, S. ...................................... 47 Hoffmann, M.M. ......................... 83, 101 Hofker, M. ........................................... 16 Hofker, M.H. ....................................... 71 Hofker, Marten ................................... 16 Hoh, B.P. ............................................ 72 Høilund-Carlsen, P.F. ....................... 45 Holaj, R. ............................................ 125 Holleboom, A. .................................... 42 Holleboom, A.G. ................................ 55 Holleman, F. ....................................... 36 Holm, N.R. .......................................... 95 Holm, S. ........................................ 65, 86 Holmgren, A. ...................................... 61 Holst, J. ............................................... 36 Holven, K. ........................................... 65 Holven, K.B. ....................................... 80 Holzer, M. ..................................... 49, 83 Homan, R. .......................................... 22 Homer-Vanniasinkam, S. ................. 94 Honarpour, N. .................................... 22 Hong, B.-K. ......................................... 70 Hong, K.W. ......................................... 38 Hong, S.P. ........................................ 112 Hong, T.J. ......................................... 111 Honye, J. ............................................ 29 Hoogeveen, R. ................................... 44 Hooper, A.J. ....................................... 82 Hori, M. ............................................. 106 Horner, D.S. ................................. 62, 63 Horovitz, A. ......................................... 84 Horvath, K. ......................................... 91 Hosseini, H. ........................................ 18 Hoteit, C. ............................................. 48 Ho-Tin-Noé, B. ............................. 30, 48 Hounslow, N. ................................ 22, 90 146 Hovingh, G.K. ..................... 2, 42, 51, 55 Hovingh, K. ......................................... 26 Howell, S.J. ....................................... 124 Hoymans, V. ..................................... 104 Hsieh, F.-I. ........................................ 100 Hsieh, I.-C. .......................................... 46 Hsu, C.................................................. 69 Hsu, L.-J. ........................................... 112 Hsu, S.-P............................................. 69 Hu, F. ..................................................... 9 Hu, Frank .............................................. 9 Hu, M. .................................................. 87 Hua, S.................................................. 66 Hua, X.................................................. 63 Huang, F. ............................................ 44 Huang, J. ........................................... 101 Huang, P.-H. ........................... 20, 29, 61 Huang, T. .......................................... 107 Huang, Y.-Y. ....................................... 29 Hubacek, J. ......................................... 99 Hubacek, J.A. ..................................... 99 Huby, T. ......................................... 57, 67 Hueb, W. ............................................. 72 Hughes, A. .......................................... 49 Hughes, A.D. .......................... 78, 89, 95 Huizinga, E.G. .................................... 61 Huk, I. ................................................ 114 Hultén, L.M. ........................................ 66 Humphries, S.E. ........................... 80, 81 Hunter, W.J. ........................................ 43 Huovinen, T. ....................................... 72 Hurme, R. ............................................ 35 Hurt-Camejo, E. ................................. 10 Husche, C. .......................................... 74 Hussain, T. .......................................... 98 Hussein, A. ....................................... 110 Hutten, B. ...................................... 26, 81 Huttl, M. ............................................... 54 Huusko, J. ........................................... 31 Huynh, K. ............................................ 30 Hwang, H.S......................................... 95 Hyötyläinen, T. ................................... 33 Hyspler, R. ........................................ 110 Hϋbner, K. ........................................... 33 I Ibañez, J.M. ........................................ 92 Ibarretxe, D. ..........................17, 36, 102 Ibrahimi, P. ................................... 98, 99 Ichiki, T. .............................................. 64 Idborg, H. ............................................ 66 Idzior-Waluś, B. ......................... 80, 127 Igarashi, A. ....................................... 118 Ikeda, N. ..................................... 58, 103 Ikeda, Y............................................... 94 Ikemoto, T. ......................................... 29 Ikewaki, K. .......................................... 40 Ikhlef, S. .............................................. 42 Ikitimur, B............................................ 59 Il`ina, L. ............................................... 86 Ilerigelen, B. ....................................... 59 Iliadis, S. ........................................... 119 Iliescu, C. .............................................. 7 Ilnicka, P. .......................................... 126 Ilyinskaya, O.P. .................................. 67 Imaeva, A. .................................. 40, 107 Imaizumi, T. ...................................... 121 Imamura, H. ................ 31, 109, 111, 123 Imamura, S. ........................................ 75 Inazu, A......................................... 50, 80 Indermuehle, A. ................................. 98 Inoue, T......................................... 50, 80 Intharapetch, P. ....................84, 99, 100 Ionova, Z.I. ......................................... 99 Iozzo, P. .............................................. 28 Iozzo, Patricia .................................... 28 Irvine, H. ............................................. 50 Isayeva, A........................................... 77 Isbir, S. ................................................ 83 Isbir, T. ................................................ 83 Ishibashi, S......................................... 73 Ishida, T. .......................... 39, 74, 75, 120 Ishihara, N. ....................................... 123 Ishizaka, N........................................ 106 Iso, H. .................................................. 48 Issa, B. ........................................ 72, 125 Itabe, H. ............................................ 123 Itai, K. ................................................ 111 Ito, H.............................................. 86, 93 147 Ito, Y. ............................................. 77, 93 Ivanisevic, J. ....................................... 94 Ivanova, M. ......................................... 84 Ivanova, O. ............................. 51, 61, 64 Ivashkin, V. ......................................... 88 Iwamoto, M. .................................. 62, 93 Iyengar, S.S. ....................................... 72 Izar, M.C. ..................................... 43, 101 Izard, J.-C. ........................................ 118 Izumi, T................................................ 56 Jegerschöld, C. .................................. 73 Jenei, Z. .............................................. 95 Jeney, V. ............................................. 29 Jenkins, P. .......................................... 97 Jennbacken, K. .................................. 35 Jensen, E............................................ 85 Jensen, G.B. ...................................... 32 Jensen, I.J. ....................................... 122 Jensen, I.-J....................................... 122 Jeon, S.W. ........................................ 112 Jeppsson, A. ...................................... 66 Jerling, J.C. ........................................ 85 Jessup, W........................................... 74 Jeurissen, M. ...................................... 22 Jevnikar, M. ........................................ 35 Jezkova, K. ......................................... 57 Jiang**, Y. ........................................... 73 Jiang, X.-C............................................ 6 Jiang, Z.S. .......................................... 29 Jiang, Z.-S. ......................................... 51 Jin, J. ........................................... 68, 116 Jo, S.-H. .............................................. 90 Joh, T. ........................................... 44, 87 Johansson, E. .............................. 98, 99 Johansson, M.E. .....................41, 66, 69 Johns, R. .......................................... 114 Johnson-Levonas, A.O. .................... 85 Jonak, P. ............................................. 56 Jonasson, L. ................................. 66, 67 Jondeau, G. ........................................ 61 Jones, P.J......................................... 123 Jonke, V. ........................................... 115 Jonker, L. ............................................ 36 Jönsson-Rylander, A.-C. .................. 35 Jorge-Galarza, E. .............................. 99 Joumard-Cubizolles, L. ................... 122 Jozkowicz, A. ..................................... 60 Juárez-Rojas, J.G. ............................ 99 Juárez-Rojop, I.E............................... 90 Jude, B. ............................................... 67 Jude, E. ............................................... 95 Juhász, I. ............................................ 95 Juhnevica, D. ................................... 107 Juhola, J. .............................................. 7 Jukema, J.W. ........ 18, 41, 47, 49, 61, 88 J Jaber, Y. .................................... 105, 110 Jabłońska, K. ...................................... 38 Jacob, M.-P......................................... 62 Jacob, N. ........................................... 113 Jafari, Dinanai, N. .............................. 70 Jahreis, G.......................................... 120 Jakic, B. ............................................... 53 Jakobsson, P.-J.................................. 66 Jakubowski, M. ................................. 126 Jalali, A. ............................................... 46 James, R.W. ....................................... 48 Jamnitski, A. ....................................... 20 Jamroz-Wiśniewska, A. ..................... 41 Janczak, D. ......................................... 38 Jandl, K. ............................................ 124 Jang, H.C. ........................................... 49 Jänis, M. .............................................. 35 Janus, A. ........................................... 126 Jaramillo, J.S. ..................................... 60 Jardim, C.C. ...................................... 116 Järvelin, M.-R. .................................... 33 Jaschke, C. ......................................... 64 Jashari, F. ..................................... 98, 99 Jasiński, K. ........................................ 106 Jaspard-Vinassa, B. .......................... 28 Jasztal, A. ........................... 89, 106, 121 Jauhiainen, M. ..... 10, 22, 31, 33, 48, 72, 128 Jauhiainen, Matti ................................ 10 Javorsky, M......................................... 99 Jawad, A.H.M. .................................... 16 Jegere, S. .......................................... 125 148 Jula, A.................................................. 33 Julius, U. ............................................. 86 Jullien, G. ............................................ 93 Julve, J. ......................................... 10, 33 Jung, I.-H. ........................................... 68 Juno, C. ............................................... 87 Juonala, M. ............................... 7, 32, 36 Jurka, A. ............................................ 103 Kanyilmaz, S. ................................... 109 Kapelak, B. ......................................... 61 Kara, E. ............................................. 119 Karabina, S. ....................................... 18 Karabina, S.-A. .................................. 47 Karadag, B. ........................................ 59 Karadeniz, F.O................................... 94 Karadi, I. ........................................... 118 Karádi, I. ............................................. 78 Karagedik, H. ..................................... 83 Karagiannis, C. .................................. 54 Karanasos, A. .............................. 38, 45 Karatzas, T. ...................................... 119 Karčiauskaitė, D. ............................. 118 Kardassis, D. ........................................ 5 Kardum, Paro, M.M. ........................ 115 Karhunen, P.J. ................................... 63 Karim, S. ............................................. 40 Karlinskaya, M. .................................. 97 Karlson, B.W. ..................................... 44 Karlsson, M.K. ............................. 7, 116 Karp, K. ............................................. 106 Karpenko, M.A. .................................. 99 Karper, J.C. ....................... 18, 41, 47, 61 Karpov, Y. ........................................... 91 Kasagi, F. ........................................... 91 Kasbi, Chadli, F. ................................ 35 Kashiwagi, A. ..................................... 91 Kashiwase, K. .................................. 109 Kaski, J.C. .......................................... 11 Kasmas, S.H. ..................................... 43 Kassi, E............................................... 93 Kassimis, G. ..................................... 114 Kassner, U.................................... 76, 80 Kastelein, J................................... 26, 81 Kastelein, J.J.P. ................................. 51 Kastorini, C.-M. ................................ 120 Katano, H............................................ 61 Kathiresan, S. .............................. 50, 51 Katkó, M. ............................................ 80 Kato, A. ............................................... 79 Kato, K. ............................................. 111 Kato, R. ............................................. 121 Katsilambros, N.L. ........................... 119 Katsuda, S. ......................................... 80 K Kacem, K. ........................................... 63 Kacem, S. ........................................... 83 Kachkovskii, M.A.......................... 78, 92 Kadota, A. ....................... 78, 91, 95, 103 Kadowaki, S........................................ 95 Kadowaki, T. ....................................... 91 Kahli, A. ............................................... 53 Kähönen, M. ........................... 7, 36, 101 Kajinami, K.......................................... 45 Kajiya, M. ............................................ 93 Kakino, A. .............................................. 6 Kakkavas, A...................................... 114 Kalachikov, S. ..................................... 18 Kalantzi, K. ........................................ 114 Kalinowski, L....................................... 57 Kalinskaya, A. ..................................... 58 Kalka, D............................................. 116 Kaltenecker, C. ................................... 49 Kaminnyi, A......................................... 66 Kaminnyi, A.I. ..................................... 84 Kamiya, K.......................................... 118 Kamstrup, P.R. ............................. 20, 32 Kanai, A. .............................................. 56 Kanai, H. ........................................... 125 Kanellakis, P. ...................................... 18 Kanellou, A. ........................................ 82 Kang, D.O. .......................................... 36 Kang, S.M. .......................................... 49 Kang, W.C......................................... 102 Kanjuh, V. ......................................... 119 Kannenberg, F. .................................. 76 Kanno, K. ............................................ 94 Kanse, S............................................ 113 Kantas, D. ......................................... 120 149 Kaudewitz, D. ................................... 114 Kaufmann, P.A. .................................. 98 Kauhanen, J. ...................................... 39 Kautznerova, D. ................................. 28 Kavurma, M. ................................. 11, 37 Kavurma, M.M. ............................. 38, 42 Kawai, Y. ............................................. 45 Kawakami, M. ..................................... 32 Kawamoto, T. ..................................... 94 Kawana, H. ................. 31, 109, 111, 123 Kawano, M. ....................................... 118 Kawasaki, M. .................................... 105 Kawase, R. ....................................... 109 Kawashiri, M.-A. ........................... 50, 80 Kawata, M. .......................................... 74 Kawatsu, Y. ................................. 78, 103 Kawecki, C. ......................................... 61 Kazanis, K. .......................................... 93 Kazdova, L. ......................................... 54 Kazemi, S.A.N. ................................... 91 Kazuma, S.M. ................................... 123 Kee, F. ................................................. 54 Kei, A.A. .............................................. 86 Keles, D. .............................................. 69 Keles, I. ............................................... 94 Kemaloglu, T. ..................................... 94 Kempen, H. ......................................... 73 Kenjaev, M. ......................................... 89 Kerek, F. .............................................. 68 Kerksiek, A.......................................... 30 Kerner, W. ......................................... 110 Kerry, Z................................................ 69 Kersten, S. .................................... 10, 75 Kersten, Sander ................................. 10 Kesavalu, L. ........................................ 63 Kessal, F. .......................... 104, 105, 115 Kessler, K.......................................... 114 Kettunen, J.......................................... 33 Keul, P. ................................................ 37 Keyamura, Y. .................................... 123 Khachigian, L. ..................................... 37 Khachigian, L.M. ................................ 38 Khalil, A. .............................................. 42 Khallou-Laschet, J. ............................ 38 Khambata, R.S. .................................. 65 Khan, F. .............................................. 64 Khan, N. .............................................. 40 Khanfir, L. ......................................... 104 Kharbanda, R.K. .............................. 112 Khasanova, Z. .................................... 84 Khatib, R. .......................................... 124 Khedoe, P.P.S.J. ............................... 65 Kidouche, R........................................ 79 Kidron, M. ......................................... 108 Kiec, A.D........................................... 121 Kiechl, S. .......................................... 114 Kihara, S. ............................................ 79 Kikuchi, K.......................................... 106 Kim, B.R. ............................................ 43 Kim, C.D. .................................38, 59, 66 Kim, C.J. ............................................. 88 Kim, D.-Y. ........................................... 68 Kim, E.J. .......................... 36, 53, 63, 122 Kim, H. .............................................. 103 Kim, H.-D. ........................................... 69 Kim, H.-H. ................................... 98, 112 Kim, H.-J. ............................................ 38 Kim, H.-S. ........................................... 90 Kim, J. ......................................... 73, 103 Kim, J.-R. .......................................... 117 Kim, J.W. ......................... 36, 53, 63, 122 Kim, J.-Y. .................................... 70, 119 Kim, K.S. ........................................... 112 Kim, M.-A. ..................................... 78, 88 Kim, M.-J. ..................................... 32, 74 Kim, S. ...................................53, 63, 122 Kim, S.-H. ..................................... 78, 90 Kim, S.-M. ........................................... 73 Kim, S.W............................................. 36 Kim, Y. ................................................ 48 Kim, Y.H. ............................................ 59 Kimura-Hayama, E. ........................... 99 Kimura-Wozniak, T............................ 59 Kindt, I. ................................................ 51 King, A. ............................................. 114 Kingwell, B.A. ..........................22, 30, 44 Kinoshita, N. ................................. 74, 75 Kinova, E. ........................................... 58 Kipinski, L. ........................................ 116 Kirchstetter, W. .................................. 87 150 Kirichenko, N. ..................................... 92 Kirkby, N.S. ....................................... 114 Kishimoto, I. ........................................ 80 Kishiro, M. ........................................... 58 Kishor, Kumar, G. .............................. 85 Kiss, Z.......................................... 78, 118 Kitamura, K. ........................................ 47 Kitas, G.D............................................ 20 Kitayama, M. ....................................... 45 Kivelä, A. ............................................. 31 Kiyonaga, A. ....................................... 54 Kjoelsnes, G. ...................................... 92 Klainman, E. ..................................... 116 Kleber, M.E. .................... 77, 80, 83, 101 Kleijn, D.P.V.D. .................................. 66 Klein, C. ............................................. 107 Klein, S. ............................................. 101 Klimcakova, L. .................................... 99 Klingenberg, R. .................................. 47 Klinger, M. ......................................... 114 Kliuk, Ben-Bassat, O. ...................... 105 Kloch-Badełek, M. ............................ 127 Klöckl, L. ............................................ 112 Knop, F. ............................................... 36 Knuuti, J. ............................................. 46 Ko, N. ................................................... 18 Kobayashi, J. ...................................... 50 Kobayashi, T............................... 40, 109 Koch, M. .............................................. 47 Kodydková, J. ..................................... 82 Koeda, Y. ............................................ 48 Koenig, W. .......................................... 28 Koh, K. ................................................. 89 Koh, K.K. ............................... 89, 95, 102 Kohashi, M. ....................................... 123 Koike, M. ............................................. 30 Koivuniemi, A. .................................... 70 Kolar, F. ............................................... 64 Kolb, D............................................... 124 Koleda, P. ......................................... 116 Kolovou, G. ................................... 81, 84 Kolovou, V. ................................... 81, 84 Komanasin, N. ...................... 84, 99, 100 Komir, I. ............................................... 77 Komuro, I. ......................................... 109 Kon, N. .............................................. 109 Koncsos, P. ...................................... 102 Kondo, K. .................................... 39, 120 Kones, R. ............................................ 17 König, W. .......................................... 101 Konings, M. .................................. 22, 30 Konnov, M. ......................................... 40 Konovalov, G. .................................... 86 Konrad, R. .......................................... 50 Kontny, F. ........................................... 92 Konttinen, J. ....................................... 96 Kontush, A. .................... 42, 72, 103, 108 Konuklugil, B. ................................... 121 Kootte, R............................................. 36 Kopecky, C. ........................................ 49 Korandji, C.......................................... 58 Korbut, R. ..................................... 60, 61 Koren, M.J. ......................................... 44 Kormi, I. .............................................. 61 Korneeva, O.N. .................................. 88 Korotaeva, A.A................................... 84 Korou, L.-M. ..................................... 119 Koryagina, N. ............................... 91, 93 Kosaki, A. ........................................... 59 Koshy, V. .......................................... 110 Kosola, J. ............................................ 69 Kostakou, P. ....................................... 84 Kostal, M. .......................................... 112 Kostapanos, M. .................................. 88 Kostogrys, R.B. .......................... 89, 121 Kotak, B. ............................................. 87 Kotoulas, C................................. 97, 104 Koubaa, N. ................................. 85, 126 Koulaouzidis, G. ................................ 97 Koutoulakis, E. ........................... 97, 104 Koutsogiannis, N. ............................ 114 Kovalcsik, E........................................ 11 Kovanen, P......................................... 14 Kovanen, P.T. .................................... 22 Kovanen, Petri ............................. 14, 23 Kovarik, J. ........................................... 49 Koverech, A.............................28, 62, 67 Koyama, T. ....................................... 123 Kozarov, E. ......................................... 18 Koziolova, N. ...................................... 79 151 Krajcoviechova, A. ....................... 40, 96 Královec, K. ........................................ 94 Krämer, S.D. ....................................... 98 Krane, V. ........................................... 101 Kratky, D. .......................................... 124 Krause, B. ........................................... 22 Krechler, T. ......................................... 82 Krempf, M. .......4, 26, 35, 44, 81, 95, 122 Krempf, Michel ..................................... 7 Kremzer, A.A. ..................................... 56 Krepuska, M. .................................... 127 Krievina, G. ............................... 103, 106 Krneta, M. ........................................... 92 Krogh-Sørensen, K. ........................... 65 Krska, Z. ............................................ 112 Kryvorot, S. ......................................... 56 Kucinskiene, Z.A. ............................... 79 Kučinskienė, Z.A. ............................. 118 Kühnast, S. ......................................... 49 Kuiper, J. ........................... 18, 41, 47, 61 Kuivenhoven, J.A. .................. 26, 42, 55 Kuivenhoven, Jan A. ......................... 26 Kukharchuk, V. ................................... 91 Kukharchuk, V.V. ............................... 84 Kukongwiriyapan, U. ........... 84, 99, 100 Kulesza, J. ........................................ 125 Kulikov, I.............................................. 84 Kumahara, H. ..................................... 54 Kume, N. ............................................. 86 Kumon, Y. ........................................... 94 Kuo, M.-S. ............................................. 6 Kurano, M. ........................................ 106 Kuranova, A. ....................................... 47 Kurl, S. ................................................. 39 Kurteva, T. .......................................... 58 Kurtoglu, H. ....................................... 126 Kusachi, S. .......................................... 93 Kusano, K. .......................................... 86 Kusters, D.M. ...................................... 51 Kusuhara, H........................................ 42 Kuznetsov, A. ..................................... 91 Kuznetsov, A.S................................. 124 Kuznetsov, V. ........................... 107, 110 Kvasnicka, J. .............................. 40, 112 Kvasnicka, T. .............................. 40, 112 Kwakernaak, A................................... 72 Kwan, P. ........................................... 126 Kwok, S....................................... 72, 125 Kwon, H.M. ................................... 70, 76 Kwon, S.W.......................................... 70 Kyaw, T. .............................................. 18 Kyrolainen, H. .................................... 69 Kzhyshkowska, J. ........................ 65, 74 L La, Guardia, P.G. .............................. 90 La, Motta, C........................................ 59 Laaksonen, R. ............................ 35, 101 Labbadia, G........................................ 31 L'Abbate, A. ........................................ 20 Labrador, Aldana, E.R. ................... 127 Laffargue, M. ................................ 16, 52 Lagarde, M. .................................. 34, 65 Lagerstedt, J.O. ................................. 73 Lagrost, L...................................... 27, 76 Lahikainen, A. .................................... 10 Lähteenmäki, H. ................................ 22 Lalere, B. ............................................ 79 Laman, J.D. ........................................ 66 Lamaze, C. ......................................... 26 Lamb, C. ........................................... 114 Lambert, G. ....................... 19, 31, 51, 73 Lamboley, J.-L. .................................. 46 Lamminmäki, U.................................. 72 Lamotte, C. ........................................... 7 Lamuela-Raventós, R.M. ................. 35 Landmesser, U. ........................... 47, 77 Lang, S. ........................................ 52, 83 Langlois, J.-B. .................................... 64 Langslet, G. .................................. 44, 80 Langsted, A. ....................................... 32 Lanhers, M.-C. ................................. 106 Lannoy, M. .......................................... 62 Lanska, M. .................................. 81, 112 Lanska, V...................................... 28, 99 Lantelme, P. ....................................... 63 Lantieri, O. ........................................ 120 Lapergue, B.............................34, 56, 57 Lappalainen, J. .................................. 30 152 Lapshataeva, O. ............................... 107 Larrieta-Carrasco, E. ......................... 99 Larsson, M. ................................... 10, 93 Lascols, O. ........................................ 100 Latkovskis, G. ................................... 107 Latouche, C. ....................................... 44 Latz, E. ................................................ 18 Latz, Eicke .......................................... 18 Laukkanen, J. ..................................... 39 Laukkanen, J.A. ................................. 39 Laurent, S. .......................................... 96 Laurila, P.-P. ....................................... 33 Lautsch, D. .......................................... 86 Laville, M. ............................................ 35 Lavoie, J.-M. ..................................... 115 Lavrador, M.S. .................................... 30 Lawrence, G. .............................. 91, 114 Lawson, D. ........................................ 124 Layeghkhavidaki, H. ........................ 106 Lazarevic, A. ....................................... 92 Lazaro, I. ............................................. 41 Le, Bras, M. .................................. 44, 76 Le, Goff, W........................ 30, 70, 72, 74 Le, May, C..................................... 6, 102 Le, Q.-H............................................... 34 Leach, N.V. ....................................... 106 Leander, K. ......................................... 36 Leask, R.L. .......................................... 56 Lebedeva, A. .......................... 51, 61, 64 Lebray, P. ............................................ 32 Lebrun, S. ......................................... 117 Lecerf, J.-M. ........................................ 50 Lechuga-Sancho, A.M....................... 10 Lecour, S. ............................................ 48 Ledesma, M. ................................. 60, 84 Lee, B.-H. ............................................ 37 Lee, B.K. ....................................... 70, 76 Lee, B.-S. ............................................ 48 Lee, C.-H........................................... 113 Lee, E.M. ............................................. 36 Lee, H.C. ........................................... 111 Lee, H.-E. ............................................ 99 Lee, H.-L. ...................................... 78, 90 Lee, H.W. .......................................... 111 Lee, J.B. ............................................ 112 Lee, K................................................ 102 Lee, K.H. ............................................. 95 Lee, M.K. ............................................ 27 Lee, R. ........................................ 86, 112 Lee, S.J....................................38, 59, 66 Lee, W.-S............................................ 69 Lee, Y.S. ........................................... 112 Lee-Rueckert, M. ............................... 33 Lefai, E. ............................................... 31 Lefeber, D.J........................................ 55 Lefebvre, P. ........................................ 67 Legeai, C. ........................................... 63 Legedz, L. ................................... 63, 101 Lehtimäki, T...........................33, 63, 101 Leighton, B. ........................................ 35 Leiherer, A. ....................................... 102 Leitão, F. ............................................. 79 Leite, Jr, A.C.d.A. ...................68, 71, 72 Lejnieks, A. ....................................... 106 Lekka, S. ............................................. 84 Lemozy, S. ......................................... 77 Lencova, O. ........................................ 57 Lenfant, F. .......................................... 37 León, M. .............................................. 84 Leopizzi, M. .................................. 28, 67 Leppänen, P. ...................................... 31 Leprince, P. ........................................ 75 Lerchbaum, E. ................................... 83 Leren, T.P........................................... 50 Leschenko, I.G............................. 78, 97 Leschenko, V.A. .......................... 78, 97 Leseche, G. ........................................ 48 Lesna, J. ........................................... 110 Lesnik, P. ............................................ 67 Lestavel, S.................................... 26, 74 Letessier, E. ......................................... 6 Letourneur, D. .................................... 57 Levade, T............................................ 80 Levashov, S. ...................................... 97 Levels, J. ............................................ 20 Levin, M. ............................................. 53 Levkau, B............................................ 37 Levonen, A.-L. ................................... 30 Levy, P. ....................................... 64, 122 Lewis, A. ....................................... 31, 76 153 Lewis, G. ............................................. 15 Lezoualc'h, F. ..................................... 37 Lhomme, M. .......................... 42, 72, 108 Li, F. ..................................................... 74 Li, J.-F.................................................. 51 Li, J.Y. .................................................. 63 Li, J.-Y. ................................................ 63 Li, K.W. ................................................ 80 Li, S. ................................................... 124 Li, S.-Y. ................................................ 20 Li, W..................................................... 67 Li, X. ..................................................... 52 Li, Y.-H. ............................................... 29 Liang, H. .............................................. 87 Liao, J.K. ........................................... 113 Libby, P. ...................................... 1, 4, 62 Liberopoulos, E.N. ............... 86, 88, 104 Libersa, C.............................................. 7 Lichtenstein, L. ................................... 16 Lien, L.-M. ......................................... 100 Liepold, E. ......................... 116, 127, 128 Liljenbäck, H. ...................................... 46 Lim, H.E. ......................... 36, 53, 63, 122 Lim, H.-J. ........................................... 103 Lim, P. ................................................. 52 Lim, S. ................................................. 49 Lim, S.I. ............................................... 36 Lima, P. ............................................... 76 Limam, F. .................................. 120, 121 Limon, I................................................ 60 Lin, C. .................................................. 30 Lin, H.-J. ............................................ 100 Lin, J. ................................................... 85 Lin, S.-J. .................................. 20, 29, 61 Lin, W.-W. ........................................... 93 Lin, W.-Y. .......................................... 100 Lin, Y. .................................................. 43 Lin, Y.-S. ............................................. 91 Lindbom, M. ........................................ 53 Lindholm, H................................. 96, 105 Lindvig, H.W. ...................................... 80 Lins, L.C. ............................................. 85 Lipp, M. .............................................. 113 Litsardopoulou, A. ............................ 120 Litvinov, D. ........................................ 108 Liu, A. .................................................. 47 Liu, E. .......................................... 29, 123 Liu, F.T. ............................................... 29 Liu, H. .................................................. 73 Liu, H.B. ............................................ 118 Liu, H.-Q. ............................................ 66 Liu, L.S. ............................................... 29 Liu, M. ................................................. 65 Liu, P. ................................................ 124 Liu, P.-Y. ...................... 29, 112, 113, 114 Liu, Q................................................... 33 Liu, T. .................................................. 44 Liu, X. .................................................. 73 Liu, Y. .......................................... 72, 125 Liu, Y.-C. ............................................. 46 Liu, Z. .................................................. 33 Liuni, A. ..................................52, 53, 125 Ljunggren, Ö. ....................................... 7 Llanos, Guerrero, C. ....................... 117 Llaverias, G. ....................................... 33 Llorente-Cortes, V. .............................. 6 Llort, M. ............................................. 102 Lodder, R. ........................................... 32 Lohez, O. ...................................... 60, 63 Longo, A. ............................................ 16 Lonsky, V. ........................................... 62 Lonzi, J.P. ......................................... 102 Lookene, A. ........................................ 10 Looker, H. ........................................... 36 López, de, Maturana, Carrasco, I. 100 Lopez, de, Maturana, I...................... 65 López, Lluva, M.T. ........................... 117 López-Maturana, I. ............................ 68 López-Requena, A. ........................... 38 Loppnow, H. ....................................... 64 Lorbeer, R. ....................................... 110 Loretz, C. ............................................ 41 Lorgis, L. ............................................. 53 Lorin, J. ......................................... 53, 58 Lőrincz, H. .............................72, 80, 102 Losurdo, P. ......................................... 35 Lotteau, V. .......................................... 66 Lottenberg, A.M. ................................ 30 Lou, C. .................................................. 6 Loued, S. ............................................ 42 154 Louedec, L. ........... 34, 38, 48, 57, 61, 62 Lounatmaa, K. .................................... 63 Lourenço, A. ....................................... 92 Lourenco, L.P. .................................... 38 Lövgren, J. .......................................... 72 Lowe, R.S. .......................................... 86 Loyau, S. ............................................. 34 Lu, J. .................................................... 33 Luc, G. ..................................... 50, 54, 81 Luca, M.C. ..................................... 52, 53 Lucas, A. ......................... 28, 52, 63, 105 Ludvigsen, T.P. .................................. 95 Ludwig, S. ................................... 34, 113 Luhman, C.J.F. ................................. 101 Lundberg, A. ....................................... 67 Lundberg, A.M. ................................... 41 Lundqvist, A. ................................. 53, 66 Lundström, E. ................................... 106 Lüscher, T.F. ...................................... 47 Lutjohann, D. ...................................... 22 Lütjohann, D. .......................... 30, 74, 83 Lychov, V. ......................................... 107 Lystsova, N. ...................................... 110 Lyytikäinen, L.-P. ....................... 40, 101 Mæhre, H.......................................... 122 Mæhre, H.K. ..................................... 122 Mafalda, B. ......................................... 79 Maggi, L. ............................................. 82 Maggio, R. .......................................... 16 Maglione, F. ....................................... 37 Magni, P. ............................................ 96 Magnussen, C.G. .......................... 7, 32 Magnusson, L.U. ............................... 66 Magré, J. ............................................... 6 Magrè, J. ........................................... 102 Mahini, H. ................................. 116, 123 Maier, W. ............................................ 47 Maifrino, L......................................... 115 Maillard, L. .......................................... 57 Maindonald, R.E. ............................. 124 Maiocchi, G. ..................................... 125 Majdalawieh, A. ................................. 30 Majeed, S. .......................................... 65 Majewski, P. ..................................... 125 Majewski, W. .................................... 125 Majnaric, L. ....................................... 111 Majnaric, L.T. ..................................... 93 Majul, C............................................... 86 Mak, S. ................................................ 53 Makariou, S.E. ........................... 88, 104 Makedou, A. ..................................... 119 Makedou, K. ..................................... 119 Mäkelä, K.-M. ................................... 101 Mäkinen, P. ........................................ 31 Makino, H. .................................. 80, 124 Makino, Y............................................ 79 Makita, Y. ...................................... 29, 55 Makoveichuk, E. ................................ 31 Makris, G. ......................................... 114 Maksimov, V. ..................................... 84 Malec, M.M. ...................................... 121 Malecki, M. ....................................... 121 Małecki, M.T. .................................... 127 Malek, I. .............................................. 28 Malet, N. ............................................. 52 Malinska, H. ....................................... 54 Mallat, Z. ............................................. 41 Mallavia, B. ......................................... 41 Mallias, I. ............................................ 82 M Ma, X. .................................................. 52 Maatouk, F. ................................... 31, 76 Mabuchi, H.................................... 50, 80 Macaluso, L. ....................................... 35 Macášek, J.......................................... 82 Mach, F. ........................................ 47, 48 Machado, R. ....................................... 30 Machida, T. ......................................... 75 Machtoub, L.H. ................................... 98 Maciag, J. ............................................ 66 Macic, Dzankovic, A. ......................... 92 MacKay, D.S..................................... 123 Mackay, M........................................... 40 Madden, S. ......................................... 22 Madder, R.D. ...................................... 22 Madjid, M. ........................................... 32 Madrigal-Matute, J. ............................ 41 Maegawa, H. ...................................... 91 155 Mallol, R. ............................................. 36 Malysheva, O. .................................. 107 Malyutina, S. ....................................... 84 Mamareli, V................................. 97, 104 Mamarelis, I.E. ................................. 104 Mameri, A.......................................... 115 Mammeri, A. ..................................... 104 Mañas, García, M.D. ....................... 117 Mandic-Radic, S................................. 94 Mandolini, C........................................ 90 Manduteanu, I. ................................... 41 Mangas, A. .......................... 92, 109, 121 Mangione, A. ...................................... 43 Manolopoulos, V.G. ........................... 81 Manolopoulou, D. ............................... 84 Manthey, H.D. .................................... 47 Mantovani, A....................................... 34 Manzini, S. .....33, 35, 58, 62, 63, 86, 126 Marais, A.D. ........................................ 81 Marais, D. ...................................... 31, 51 Maranghi, M. ........................... 10, 31, 84 Maranhao, R.C. ................................ 115 Maranhão, R.C. ...................... 68, 71, 72 Maraninchi, M. .................................. 101 Marcais, C. .......................................... 82 Marçais, C. .................................... 31, 74 Marcantonio, P. .................................. 90 March, K. ............................................. 95 Marchan, Carranza, E. .................... 117 Marchetti, G. ....................................... 60 Marchon, C. ...................................... 115 Marciniak, W. .................................... 116 Marcoyannopoulou, Fojas, H. ........ 101 Marcucci, R. .................................. 70, 95 Marduel, M. ......................................... 50 Margariti, P. ...................................... 126 Margaritis, M. .................................... 112 Margolis, L. ............................. 51, 61, 64 Marina, Breysse, M.......................... 117 Marinari, E..................................... 28, 67 Mark, L. ............................................. 118 Márk, L. ............................................... 78 Markatseli, T.E. ................................ 126 Markovic-Lipkovski, J. ..................... 119 Markus, H.S. ..................................... 114 Marleau, S. ......................................... 68 Marmash, N........................................ 65 Marmontel, O. .............................. 74, 82 Marotta, G. ......................................... 51 Marques, L. ........................................ 52 Marques-Pinheiro, A. ........................ 26 Marre, M. .......................................... 120 Marsche, G. .................................. 49, 83 Marszałek, A. ................................... 125 Marta, D. ........................................... 110 Martin, C. ...................................... 80, 81 Martin, L. ............................................. 57 Martín-Campos, J.M. ........................ 10 Martinez, Comendador, J.M. ........... 88 Martinez, L.................................... 52, 85 Martinez, L.O. .................................... 16 Martinez, M. ....................................... 54 Martinez, Martinez, A. ................. 97, 98 Martínez-González, M.Á................... 35 Martín-Ventura, J.L. .......................... 41 Martiny, L. ........................................... 52 Mary-Krause, M. .......................... 52, 83 März, W. .......................... 77, 80, 83, 101 Marzocchi-Machado, C.M. ............... 93 Marzougui, F. ................................... 104 Mas, A. .............................................. 110 Masana, L..............................17, 36, 102 Mascoli, F. .......................................... 60 Mashayekhi, S. .................................. 66 Maslak, E. ................................... 89, 121 Maślak, E. ......................................... 106 Masoura, C. ........................................ 44 Massama, L...................................... 121 Mastroiacovo, D................................. 90 Masuda, D. ................................. 87, 109 Masuda, T. ....................................... 118 Mata, K. .............................................. 95 Mateo-Gallego, R. ............................. 84 Mateuszuk, L.............................. 89, 121 Matos, L.N. ................................... 43, 85 Matsuda, M. ....................................... 94 Matsuda, T. ........................................ 54 Matsumoto, T. .................................... 32 Matsumura, T. .................................... 55 Matsunaga, A. .................................. 108 156 Matsuo, K. ........................................... 73 Matsuoka, E........................................ 59 Matsuoka, T. ....................................... 79 Matsushima, T. ................................. 106 Matsuyama, A. ................................. 109 Mattei, C. ........................................... 101 Matter, C.M. ........................................ 47 Mattner, F............................................ 87 Maurice, P. .................................... 52, 61 Mavronasiou, E. ............................... 114 Mayasari, D.S. .................................... 11 Mayer, O. ...................................... 40, 96 Mayr, M. ............................................ 114 Mažeikienė, A. .................................. 118 Mazer, N.A. ................................... 33, 77 Mazerkina, N.A................................. 105 Mazighi, M..................................... 34, 56 Mazur, A. ........................... 107, 118, 122 Mazzolai, L.......................................... 17 Mazzone, A. .......................... 61, 93, 108 Mazzucco, S. .......................... 64, 65, 67 Mazzuco, T.L. ................................... 109 Mc, Loughlin, S. ............................... 119 McDonald, K. ...................................... 56 McKeigue, P. .......................... 36, 49, 78 McKenney, J.M. ................................. 87 McLaughlin, K............................. 52, 125 McNamara, R. .................................... 22 Meagher, E.A. .................................... 81 Meani, P. ........................................... 110 Mechtouff, L. ....................................... 46 Medbury, H. ........................................ 65 Medeiros, A.M. ................................... 81 Medvedeva, E. ................................... 60 Medvegy, M. ..................................... 102 Meguro, Y. .......................................... 93 Mehinagic, D....................................... 92 Mehri, S. .............................. 85, 101, 126 Mehta, V. ............................................. 59 Meikle, P. .......................................... 119 Meikle, P.J. ................................... 22, 30 Meilhac, O. .......34, 38, 48, 56, 57, 64, 73 Meinitzer, A. ...................................... 101 Melander, O. ....................................... 17 Melchionna, S..................................... 99 Meletta, R. .......................................... 98 Mellal, K. ............................................. 68 Mellis, S. ............................................. 26 Mellström, D. ........................................ 7 Melnichenko, A.A. ............................. 71 Melnichenko, G. ................................. 97 Melone, M. .............................48, 71, 105 Mendoza, J. ........................................ 26 Mendoza-Barberà, E......................... 10 Menegazzi, M. ................................... 67 Mensink, R. ........................................ 30 Mensink, R.P................................ 22, 74 Mention, K. ......................................... 80 Merino, J. ...............................17, 36, 102 Merkely, B. ....................................... 127 Merkler, A. .......................................... 82 Merlin, M. ............................................ 74 Meroño, T. ........................................ 108 Metaxa, V. .......................................... 44 Metelskaya, V.A................................. 79 Metso, J. ........................................... 128 Meurs, I. .............................................. 65 Meydani, M. ...................................... 126 Mező, I. ....................................... 78, 118 Mezzano, D. ....................................... 34 Mezzetti, A.......................................... 90 Miantezila, Basilua, J. ....................... 83 Miarka, P. ......................................... 127 Micallef, P.A. ...................................... 66 Miccoli, R. ........................................... 51 Miceli, A. ............................................. 93 Michalsky, D. .................................... 125 Michel, J.B. ..............................34, 38, 48 Michel, J.-B. ..............................5, 30, 34 Michel, J.-B. ....................................... 48 Michel, J.-B. ....................................... 56 Michel, J.-B. ....................................... 57 Michel, J.-B. ....................................... 61 Michel, J.-B. ....................................... 64 Michel, J.-B. ..................................... 114 Michishita, R. ..................................... 54 Mickley, H. .......................................... 45 Mihas, C. ............................................ 84 Mikhailidis, D.P. ......................45, 49, 50 Mikolajczyk, T. ............................. 60, 61 157 Mikołajczyk, T. .................................. 116 Mikolajczyk, T.P. ................................ 66 Miled, A. ........................................ 31, 76 Milei, J. .............................................. 119 Milenkovic, D. ..................... 43, 107, 118 Milidis, T. ............................................. 82 Milionis, H.J. ..................................... 120 Miliou, A. ............................................. 44 Miljkovic, M. ........................................ 94 Millar, J. ................................................. 2 Miller, K. .............................................. 26 Miller, S.A............................................ 82 Min, P.-K. ............................................ 70 Minakawa, Y. ...................................... 93 Miname, M. ......................................... 42 Minelli, S............................................ 107 Ming, J. ................................................ 47 Ming, W. .............................................. 65 Minicocci, I. ................................... 10, 31 Mintale, I............................................ 125 Minutolo, A. ......................................... 16 Miranda-Zamora, R. .......................... 90 Mirel, D. ............................................... 33 Mislea, O. .................................. 104, 107 Mitani, K. ........................................... 123 Mitchenko, O. ..................................... 82 Miteva, Y. .......................................... 108 Mitrofanov, K.Y. ................................ 100 Mitrogianni, Z. ..................................... 76 Mitterhofer, A.P. ........................... 28, 67 Mittlboeck, M. ................................... 114 Miura, K. ............................ 48, 77, 91, 95 Miura, S. ............................................ 108 Miura, Y. .............................................. 62 Miyagawa, N. ...................................... 95 Miyamatsu, N. ............................ 78, 103 Miyamoto, Y. ....................................... 80 Miyashita, K. ................................. 74, 75 Miyoshi, T...................................... 86, 93 Mizue, H. ............................................. 93 Mizuno, S. ..................................... 29, 55 Mizuno, T. ................................... 42, 106 Mlynarik, V. ......................................... 17 Mmamarelis, I.E. ................................ 97 Modéer, T............................................ 63 Mody, F. ............................................ 111 Moesgaard, S.G. ............................... 95 Mohd, Ishak, N.H............................... 66 Mohd, Ismail, A. ......................58, 66, 72 Mohd, Kornain, N.K........................... 58 Mohd, Mokhsin, N.A.......................... 72 Mohd, Nawawi, H. ..................58, 66, 72 Moisenovich, M. ................................. 74 Moldoveanu, E. ................................ 110 Mollaki, V. ........................................... 81 Möller, B. .......................................... 106 Mombelli, G. ....................................... 96 Momiyama, Y. .................................. 121 Momot, A. ......................................... 100 Monaco, C. ......................................... 63 Monguchi, T. .............................. 39, 120 Monier, S. ......................................... 104 Monk, D. ............................................. 74 Montalescot, G................................. 5, 8 Montali, A............................................ 31 Montecucco, F. ............................ 47, 48 Monterio, A.M. ................................. 101 Moon, J. .............................................. 95 Moon, M.K. ......................................... 49 Moore, K. ............................................ 15 Moore, K.J. ......................................... 37 Moore, X.L. ......................................... 27 Morand, C. ...........................43, 107, 118 Morange, P.-E.................................... 54 Mordhwaj, P. .................................... 108 Moreira, T.B. ................................ 71, 72 Moreno, J.-A. ..................................... 56 Moreno, L.A.......................................... 7 Moreyra, E. ................................. 96, 102 Morgantini, C...................................... 35 Mörgelin, M. ....................................... 73 Mori, K....................................39, 74, 120 Mori, M. ......................................... 50, 80 Mori, T. ...................................... 119, 120 Mori, Y................................................. 59 Moriarty, P.M. ................................... 124 Morimoto, A. ............................... 78, 103 Morino, A. ................................... 78, 103 Morita, H. ............................................ 86 Morozov, A. ........................................ 18 158 Morozov, I.A. ...................................... 62 Morvan, M. .......................................... 38 Moshkin, A.V. ................................... 105 Moskaleva, N. ..................................... 56 Mossinson, D. ................................... 116 Mostowik, M. ....................................... 39 Motazacker, M.M. .............................. 55 Motocu, M. ........................................ 104 Moulias, A. ........................................ 114 Moulin, P. .............4, 9, 31, 34, 74, 81, 82 Moulin, Philippe .............................. 4, 15 Moulopoulos, L. .................................. 82 Moura, F. ............................................. 78 Mousavinasab, S.N. .......................... 91 Moussa, A. .................................... 83, 92 Moutzouri, E. ...................................... 88 Movassaghpur, A. .............................. 66 Mozwillo, J.S..................................... 121 Mrowiecki, T. ...................................... 61 Mrowiecki, W. ..................................... 61 Mrudula, Spurthi, K. ........................... 85 Mu, L. ................................................... 98 Muačević-Katanec, D. ....................... 82 Muchova, L. ...................................... 120 Muderrisoglu, H. ............................... 109 Müderrisoğlu, H. ......................... 89, 107 Muggia, C.......................................... 101 Mühlberg, K. ..................................... 107 Mulder, M. ........................................... 70 Muller, A. ........................................... 119 Müller, A. ............................................. 98 Muller, C. ....................................... 37, 70 Müller, G.............................................. 86 Muller, J.E. .......................................... 22 Müller-Werdan, U............................... 64 Muller-Wieland, D. ............................. 86 Münch, R. ............................................ 68 Mündlein, A. ...................................... 102 Münzel, T. ............................................. 8 Murakami, M. ...................................... 75 Murakami, Y. ................................ 48, 95 Murano, T. ................................... 31, 111 Muro, A. ................................... 52, 62, 94 Murohara, T. ............................... 58, 103 Musikhina, N. ............................ 107, 110 Musil, F. ............................................ 110 Musliner, T.......................................... 85 Mustafina, S. .................................... 102 Mysliwiec, M. .............................. 78, 111 N Na, J.H. ..................................53, 63, 122 Na, J.O................................................ 36 Nachtigal, P. ..........................57, 89, 120 Naderi, G.A. ....................................... 70 Nael, C. ............................................. 122 Naelten, G. ....................................... 123 Naessen, T. ........................................ 93 Nagano, C. ....................................... 123 Nagashima, S. ................................... 73 Nagayama, D. ............. 31, 109, 111, 123 Nagel, E. ............................................. 98 Nagumo, A. ................. 31, 109, 111, 123 Nair, A. ................................................ 81 Nair, D. ................................................ 81 Nakajima, H...........................39, 74, 120 Nakajima, K. ................................. 74, 75 Nakamoto, K. ..................................... 94 Nakamura, K. ..................................... 86 Nakamura, M. .............................. 32, 48 Nakamura, S. ............................... 29, 55 Nakamura, Y. ............................... 76, 91 Nakandakare, E. ...................30, 83, 109 Nakandakare, E.R. .......................... 128 Nakanishi, C. ................................ 50, 80 Nakaoka, H. ..................................... 109 Nakatani, K....................................... 109 Nakayama, K. .................................... 11 Nakayama, R. .................................... 93 Nakbi, A. ..................................... 85, 126 Naknadakare, E. ................................ 78 Namiki, A. ........................................... 55 Nanjee, M.N. ...................................... 33 Nanobachvili, J. ............................... 114 Naoi, S. ............................................... 42 Napoli, A. ............................................ 97 Nara, M. .............................................. 75 Narbute, I. ......................................... 125 Narverud, I.......................................... 80 159 Nash, G. .............................................. 34 Näslund, U. ......................................... 61 Natali, A. ........................................ 20, 35 Natoli, A.K. .......................................... 44 Nauck, M. .......................................... 110 Naukkarinen, J. .................................. 33 Nawawi, H. ........................................ 120 Nayeri, H. ............................................ 70 Nazarkina, I.M. ................................... 78 Nazih, E.-H. ........................................ 35 Ndiaye, N.C. ..................................... 106 Neffati, S. .................................... 92, 104 Neggazi, S. ......................................... 74 Negrao, C.E. ..................................... 115 Negrean, V................................ 104, 107 Negre-Salvayre, A. ............................ 70 Nègre-Salvayre, A. ...................... 37, 38 Negro, A. ....................................... 28, 67 Nekaies, Y. ................................. 79, 119 Nematbakhsh, M. ............................... 56 Nemeckova, I. ............................ 57, 120 Nemoto, T. .......................... 73, 109, 122 Nessler, J. ........................................... 39 Nestel, P............................................ 119 Neumayer, C. ................................... 114 Newby, A.C. ........................................ 59 Newby, D.E. ...................................... 124 Newman, J. ....................................... 122 Ng, T.W. .............................................. 30 Ngallhy, E.......................................... 105 Ngo, Sock, E.T. ................................ 115 Nguyen, M.T. .................................... 110 Nguyen, P. .......................................... 35 Niccoli, G. .................................... 40, 107 Nicholls, S. .......................................... 22 Nicholls, S.J. ....................................... 45 Nicoletti, A. .......................................... 38 Nicoll, R. .............................................. 97 Nielsen, S.F. ....................................... 40 Nieuwdorp, M. .................................... 36 Nieves, J. ............................................ 80 Nighoghossian, N. ....................... 46, 64 Niimi, M. ............................................ 123 Niiyama, M. ......................................... 32 Nijhuis, M.M.O. ................................... 66 Nikfar, S. ..................................45, 49, 50 Nikiforov, N. ........................................ 74 Nikiforov, N.G. ................................... 70 Nikitin, Y. ............................................ 84 Nikitskaya, E. ............................... 51, 64 Nikolaou, C......................................... 38 Nikolaou, V. ...................................... 120 Nikolic, D. ................................45, 49, 50 Nilsson, J. ........................ 18, 21, 75, 110 Nilsson, Jan........................................ 21 Nilsson, M. .................................... 7, 110 Nilsson, S. .......................................... 75 Nilsson, S.K.................................. 10, 31 Ninio, E. .................................18, 47, 117 Nishida, M. ....................................... 109 Nishikawa, T. ............................. 78, 103 Nishimoto, O. ..................................... 94 Nishinari, M. ....................................... 56 Nishio, M. .......................................... 122 Nishiuchi, J. ........................................ 94 Nishiyama, H...................................... 94 Nissen, S. ........................................... 15 Nitulescu, M. .................................... 110 Niwano, S. ........................................ 118 Nizomov, A. ........................................ 89 Nizomov, A.A. .............................. 65, 89 Noa, M. ............................................... 38 Nobecourt, E. ..................................... 44 Nobrega, O. ........................................ 71 Noce, V. .............................................. 97 Noda, C............................................. 118 Noels, H. ............................................. 67 Noeva, E. ............................................ 47 Nofer, J.-R. ......................................... 76 Nofroni, I. ...................................... 28, 67 Noguchi, T. ................................... 50, 80 Nogueira, M................................ 53, 116 Nohara, A. .................................... 50, 80 Nollace, A. .......................................... 74 Nony, S. .............................................. 82 Norata, D. ........................................... 33 Norata, G.D. ... 33, 34, 37, 52, 62, 67, 68, 94, 112 Norata, Giuseppe Danilo .................. 23 Nordestgaard, B. ............ 1, 3, 28, 36, 55 160 Nordestgaard, B.G. 7, 20, 32, 40, 54, 84 Nordestgaard, Børge ........................... 3 Nosaka, K. .......................................... 93 Nosalski, R.................................... 60, 66 Noto, D. ............................................... 51 Novak, K............................................ 125 Novakovic, R. ................................... 119 Nozadze, D. ........................................ 75 Nozako, M. ........................................ 123 Ntalas, I. ............................................ 114 Nunes, V. ............................................ 30 Nunes, V.S.......................... 83, 109, 128 Núñez, I. .............................................. 35 Nurgazieva, D..................................... 65 Nurmohamed, M.T. ............................ 20 Nusshold, C. ..................................... 124 Nykonenko, O................................... 114 Nyrén, R. ............................................. 75 Ohsuzu, F. ........................................ 121 Oikonen, M. .................................. 36, 40 Oikonomou, E. ................................... 44 Okada, T. .......................................... 109 Okamura, T. ........ 48, 77, 78, 80, 91, 103 Okayama, A. .............................. 77, 111 Oksala, N. ......................................... 101 Oktay, G. ............................................ 69 Okumura, K. ............................... 58, 103 Okutsu, R.......................................... 123 Okyay, K. .............................89, 107, 109 Oláh, A.V. ........................................... 72 Olano-Martin, E. ................................ 80 Oliva, I. ................................................ 74 Olivato, S. ................................64, 65, 67 Olivecrona, G. .........................10, 31, 75 Olivecrona, T...................................... 31 Oliveira, A.E.F.D. ..................... 126, 127 Oliveira, H.C.F. ................................ 101 Olkkonen, V........................................ 31 Olkkonen, V.M. .................................... 6 Olkkonen, Vesa M ............................... 6 Ollivier, V. ..................................... 30, 61 Olsen, L.H. ......................................... 95 Omata, K. ......................................... 125 Omezzine, A. ........................83, 92, 104 Ong, H................................................. 68 Onoda, T..................................... 32, 111 Onodera, M. ....................................... 32 Öörni, K......................................... 10, 22 Opstad, T.B. ....................................... 55 Oravec, S.............................79, 108, 115 Orekhov, A. ........................................ 72 Orekhov, A.N. ........... 62, 70, 71, 74, 100 Orekhova, V.A. .................................. 71 Oresic, M. ........................................... 33 Orho-Melander, M. ...............17, 39, 101 Orsoni, A..................................... 90, 103 Orsoni, A.K. ........................................ 22 Ortega, E. ......................................... 126 Ortiz, G. .............................................. 34 Osaba, L. ............................................ 80 Ose, L. ................................................ 80 Oshima, S................................... 35, 109 Osipenko, A.N.................................... 77 O Obika, S. ............................................. 44 Obrowsky, S. .................................... 124 Obuchi, A. ......................................... 121 Oda, H. ................................................ 58 Odurny, A. ......................................... 114 Oe, H. .................................................. 86 Ogawa, M. ........................................... 32 Oguiza, A. ........................................... 41 Ogura, M. ............................................ 40 Oh, D.J. ........................... 36, 53, 63, 122 Oh, G.T................................................ 68 Oh, J.-H. ............................................ 111 Oh, P.C........................................ 89, 102 Ohama, T. ......................................... 109 Ohguro, T. ........................................... 94 Ohira, M. ..................... 31, 109, 111, 123 Ohkawa, K. ......................................... 93 Ohkubo, T. .............................. 77, 91, 95 Ohlsson, C. ........................................... 7 Ohmori, R.......................................... 121 Ohno, Y. .............................................. 86 Ohnuki, T. ......................................... 127 Öhrvik, J. ............................................. 36 Ohsawa, M. ................................. 48, 111 161 Østerud, B. ........................................ 122 Osuga, J.-I. ......................................... 73 Oszkinis, G. ...................................... 125 Otero-Losada, M. ............................. 119 Othmani, K. ....................................... 119 Ott, A. ................................................ 102 Ottaviano, G. .................................... 119 Ou, H.-Y. ............................................. 29 Oudar, O. ............................................ 57 Ougerram, K. ...................................... 95 Ouguerram, K. ................ 26, 35, 50, 122 Out, C. ................................................. 36 Ouyang, X.-P. ..................................... 71 Ovsyi, I. ............................................... 65 Oyedokun, B. .................................... 120 Ozansoy, G. ...................................... 121 Ozbal, S. ............................................. 69 Özçalık, E.......................................... 107 Ozerova, I.N. ...................................... 79 Ozturk, Z. ............................................ 59 Palombo, D. ....................................... 47 Palotie, A. ........................................... 33 Pan, X. ................................................ 30 Panagiotakos, D.B. ......................... 120 Panagopoulou, I. ............................... 88 Panariti, F. ........................................ 125 Pane, B. .............................................. 47 Panes, O............................................. 34 Pang, J.............................................. 103 Panizon, E. ......................................... 35 Pankajakshan, D. .............................. 51 Panov, D. .......................................... 117 Pantopoulou, A. ............................... 119 Panzoldo, N.B. ......................71, 83, 128 Papadimitriou, L................................. 44 Papafaklis, M.I. ............................ 29, 55 Papageorgiou, G. ............................ 119 Papagoras, C. .......................... 106, 126 Papanikolaou, A. ............................... 45 Papastefanou, E. ............................... 82 Paradela-Dobarro, B. ........................ 57 Paradossi, U. ................................... 108 Paradowski, M. ................................ 102 Paragh, G. ......... 72, 78, 80, 95, 102, 118 Parahuleva, M.................................. 113 Paranhos, G. ...................................... 90 Parfenov, A. ....................................... 39 Parfenova, N.S. ............................... 124 Parhofer, K. .......................................... 5 Park, C.G. ........................................... 36 Park, C.-G. ......................................... 53 Park, C.-G. ......................................... 63 Park, C.-G. ....................................... 122 Park, C.M............................................ 95 Park, D.-G. ................................... 78, 90 Park, G.-Y. .......................................... 73 Park, H.-Y. .................................. 32, 103 Park, J.E. ............................................ 48 Park, J.H. .................................... 63, 122 Park, K.-H. ........................................ 117 Park, S.Y. ................................38, 59, 66 Park, Y.W. ........................................ 112 Parker, J. ............................................ 53 Parker, J.D. ................................ 52, 125 Parkes, H. ........................................... 79 P Pacha, J. ............................................. 64 Pacienza, N. ....................................... 82 Packard, C. ................................... 19, 25 Packard, Chris .................................... 19 Padilla, N. .......................................... 101 Pados, G. .................................... 78, 118 Padra, J. .............................................. 80 Padro, T. ............................................... 6 Pagano, S. .......................................... 47 Pagnier, A. .......................................... 80 Pagoni, S. ............................... 54, 82, 95 Paillard, F. ................................. 121, 123 Paim, B.A. ......................................... 101 Pais, de, Barros, J.-P. ....................... 27 Pais, R. ................................................ 32 Pal, P. .................................................. 78 Palacios, L. ......................................... 80 Palagi, P.M. ........................................ 60 Palatkina, L. ........................................ 88 Palladini, G. ........................................ 61 Palmer, M.K. ....................................... 44 Palmieri, C. ....................................... 108 162 Parlevliet, E.T. .................................... 16 Parodi, O. ...................................... 62, 67 Parolini, C. .......... 33, 35, 58, 62, 63, 126 Parra, E.S. ............................ 78, 83, 128 Parri, A. ............................................. 109 Parthasarathy, S. ................. 11, 65, 108 Parviz, B. ........................................... 113 Pasanisi, F. ......................................... 43 Paschopoulos, M. .............................. 57 Pashang, M......................................... 46 Pasqual, N. ......................................... 47 Passarelli, M. .................................... 109 Passet, M. ........................................... 30 Pasterkamp, G. .................................. 66 Patankar, J.V. ................................... 124 Patti, L. ................................................ 43 Patuzzo, C. ......................................... 65 Paul, J.-L. ............................................ 30 Paula, H. ............................................. 53 Paultre, C. ................................... 63, 101 Paumelle, R. ............................... 28, 105 Paus, A. ............................................... 92 Pavanello, C. ...................................... 96 Pavão, M.L.......................................... 91 Pavlova, M.G. ................................... 105 Pavlunina, T. ....................................... 66 Pavlunina, T.O. .................................. 84 Pawlak, D. ................................... 78, 111 Pawlak, K. ................................... 78, 111 Paximadas, S. .............................. 54, 95 Pazzucconi, F. .................................... 96 Pedersen, H.D. ................................... 95 Pedersen, T. ....................................... 19 Pedersen, Terje.................................. 19 Pedrico, D. ........................................ 102 Pedro-Botet, J. ......................... 109, 110 Pedros, C. ........................................... 52 Peel, S. ................................................ 98 Peitsch, M.C. .................................... 117 Peitzsch, M. ........................................ 40 Pellegatta, F. ........................ 67, 68, 112 Pellegrin, M. ........................................ 17 Pellet-Many, C. ................................... 59 Pelosi, G........................................ 62, 67 Peloso, G. ........................................... 50 Pencina, M.J. ..................................... 45 Pende, A. ............................................ 47 Peng, J................................................ 73 Peng, J.-Y. .......................................... 51 Pera, M. ............................................ 109 Pereira, A............................................ 92 Pereira, V.H........................................ 92 Pereira-da-Silva, T. ........................... 53 Pérez, A. ....................................... 38, 68 Perez, Martinez, P........................... 119 Pérez-López, J................................... 84 Pérez-Méndez, O. ............................. 77 Pergolini, D......................................... 31 Perkov, S. ......................................... 115 Perlini, S. ............................................ 61 Pernalete, Bustos, I.C. .................... 117 Perova, N.V. ....................................... 79 Perrea, D.N. ..................................... 119 Perret, B. ...................................... 16, 85 Perret, M. ............................................ 64 Perret, P. ............................................ 99 Perrin-Cocon, L. ................................ 66 Perrot, L. ............................................. 82 Perségol, L. ...................................... 104 Persson, A. ....................................... 110 Persson, L. ......................................... 39 Pervushina, N. ................................... 70 Pessi, T. .............................................. 63 Petelina, T. ............................... 107, 110 Petit, J.-M. .................................. 27, 104 Petrak, O. ......................................... 125 Petrashevskaya, T. ......................... 110 Petrek, M. ........................................... 62 Petri, M. .............................................. 64 Petrides, F. ......................................... 51 Petrii, M.H. ........................................ 122 Petrischeva, A.................................... 93 Petrischeva, A.V. ............................... 91 Petrkova, J. ........................................ 62 Petrlova, J. ......................................... 73 Pettersen, A.Å.................................... 55 Pettersson, K. .............................. 18, 72 Pfeiferova, J. .............................. 57, 120 Philippe, M.......................................... 38 Phinikaridou, A................................... 58 163 Picard, P............................................ 123 Pichler, M. ........................................... 86 Piechota-Polanczyk, A. ................... 114 Pierce, G.N. ........................................ 60 Pietri, S. ............................................. 100 Pigna, G. ............................................. 31 Pignatti, P.F. ....................................... 65 Piksasova, O. ..................................... 36 Pilecki, W. ......................................... 116 Pileggi, S. .......................................... 100 Pillegand, C. ..................................... 105 Pillois, X. ............................................. 84 Pillot, B. ................................................. 6 Pilz, S. ......................................... 83, 101 Pinegina, N. .................................. 51, 64 Pinilla, Echeverri, N. ........................ 117 Pinna, C. ............................................. 58 Pinotti, E. ............................................. 51 Pinto, G.A............................................ 85 Pintó, X. ............................................... 35 Pinyol, M. .......................................... 126 Piotrowska, A. .................................... 38 Piqueras, Flores, J. .......................... 117 Pirault, J. ............................................. 67 Pirk, J................................................... 28 Pirruccello, J.P. .................................. 50 Pirvulescu, M. ..................................... 41 Pirvulescu, M.M.................................. 41 Pissaridi, K. ................................. 97, 104 Pitha, J. ......................................... 28, 99 Pitivej, Thurakit, P. ..................... 84, 100 Pitsavos, C.......................................... 44 Plana, N. ............................... 17, 36, 102 Plantaz, D. .......................................... 80 Plat, J......................... 14, 22, 30, 74, 118 Plomp, J.J. .......................................... 65 Pocoví, M. ........................................... 84 Podhorska-Okołów, M. ...................... 38 Pogorelova, O. ................................... 91 Pohlmann, A.R. ................................ 123 Poitry-Yamate, C................................ 17 Pojskic, B. ........................................... 92 Pojskic, M. ........................................... 92 Pokrovsky, S................................. 86, 87 Poledne, R. ............................. 28, 64, 99 Polimeni, L.......................................... 84 Polis, A.B. ........................................... 85 Polonskaya, Y. ................................. 127 Polyanskaya, E. ................................. 79 Ponkin, S. ........................................... 91 Pons, J. ............................................... 87 Popova, A. .......................................... 65 Portelance, S.G. ................................ 68 Português, J. ...................................... 92 Posadas-Romero, C. .................. 77, 99 Posadas-Sánchez, R. ....................... 99 Postmus, I. ......................................... 88 Potekhina, A. ...................................... 47 Poteshkin, Y. ...................................... 97 Potor, L. .............................................. 29 Povoa, R.M. ....................................... 43 Power, P. ...............................48, 71, 105 Pozzi, C. ........................................... 112 Prathiba, N. ........................................ 85 Prehn, C. .................................... 75, 110 Prieur, X. ....................................... 6, 102 Princen, H.M.G. ........................... 49, 71 Proietta, M. ..............................28, 62, 67 Prokazova, N. .................................... 66 Prolini, C. ............................................ 86 Proniewski, B. ............................ 57, 106 Prosser, H. ......................................... 42 Prostran, M. ................................ 94, 113 Protti, A. .............................................. 58 Proust, C........................................... 117 Provatorov, S. .................................... 47 Prüfer, J. ........................................... 107 Prüfer, N. .................................. 107, 112 Prugger, C. ......................................... 54 Pucheu, Y. .......................................... 84 Puig, de, Dou, J. .............................. 110 Pujos-Guillot, E. ............................... 122 Pukite, K. .......................................... 113 Pulakazhi, Venu, V.K. ............52, 62, 94 Puntmann, V. ..................................... 98 Puntoni, M. ......................................... 62 Puntoni, M.R. ..................................... 67 Puri, R. ................................................ 22 Pussinen, P. ....................................... 61 Pylaeva, E. ......................................... 47 164 Rantakömi, S.H. ................................ 39 Rantapää-Dahlqvist, S.................... 106 Raposeiras-Roubín, S. ..................... 57 Ras, R.T. ............................................ 43 Rashid, S. ..............................48, 71, 105 Raskina, K. ......................................... 47 Rasmussen, K.L. ............................... 84 Rastelli, F.......................................... 112 Ratziu, V. ............................................ 32 Raungaard, B. .................................... 50 Rauramaa, R...................................... 39 Ravagnani, F.G. ................................ 90 Ray, K.K. ............................................ 45 Ray, P.C. ............................................ 75 Raymond-Letron, I. ........................... 37 Rebhi, L. ................................83, 92, 104 Recio, C. ............................................. 41 Reddy-Luthmoodoo, M. .................... 44 Redfors, B. ......................................... 53 Reel, B. ....................................59, 60, 69 Reffelmann, T. ................................. 110 Rehakova, L. ...................................... 64 Reiber, I. ..................................... 78, 118 Reichardt, F........................................ 75 Reija, Lopez, L. ................................ 125 Reijnders, D. ...................................... 36 Reiner, Ž. ............................................ 82 Reiner, Zeljko ..................................... 17 Rejeb, J..................................83, 92, 104 Remaley, A. ........................................ 22 Remaley, A.T. .................................... 27 Ren, Z. ................................................ 29 Renard, M. ........................................ 109 Renault, M.-A. .................................... 28 Rensen, P.C.N. ................. 16, 49, 65, 71 Rensen, S........................................... 71 Ressureição, K. ............................... 115 Retterstøl, K. ...................................... 80 Revuelta-Lopez, E............................... 6 Rewiuk, K. ........................................ 116 Rey, A. .............................................. 122 Reynaud, A. ....................................... 84 Rha, S.-W. ....................... 36, 53, 63, 122 Riahin, A. ............................................ 63 Riant, E. .............................................. 49 Pyysalo, M. ......................................... 63 Q Qian, H. ............................................... 40 Qian, S. ............................................... 33 Quan, H. .............................................. 40 Quax, P. ........................................ 18, 61 Quax, P.H.A. ................................. 41, 47 Quelhas, I............................................ 92 Quillard, T. .......................................... 62 Quinn, C.M. ......................................... 74 Quintao, E. .......................................... 30 Quintao, E.C.R. ............................ 78, 83 Quintão, E.C.R. ................................ 128 Quon, M. ............................................. 89 R Raal, F. .......................................... 22, 44 Raal, F.J. ....................................... 15, 44 Rabelink, T.J......................................... 8 Rabès, J.-P. .................................. 26, 50 Rached, F.H. ...................................... 42 Radenković, M. ................................ 113 Rader, D. ............................................. 10 Rader, D.J. .................................... 10, 81 Radovic, B. ....................................... 124 Ragia, G. ............................................. 81 Ragino, Y. ................................... 91, 127 Rahimian, R. ....................................... 56 Rahman, T. ....................................... 120 Rainger, E. .......................................... 34 Raitakari, O. ........................................ 33 Raitakari, O.T. ............ 7, 32, 36, 40, 101 Raitoharju, E. .................................... 101 Rajesh, Kumar, G. ............................. 85 Rakowska, A..................................... 116 Ramet, J. ........................................... 104 Ramón, J.M. ..................................... 109 Ramos, J. .......................................... 118 Ramos, S.G. ....................................... 95 Rancic, Z. ............................................ 98 Rangé, H. ............................................ 64 Ranheim, T. ...................................... 113 165 Ribalta, J. ...................................... 36, 74 Riccardi, G. ......................................... 43 Ricordeau, P. ...................................... 32 Riga, M. ............................................... 45 Rigotti, A.............................................. 34 Riklund, K............................................ 61 Rim, S.-J. ............................................ 70 Rio, P. .......................................... 53, 116 Riou, L.M. ............................................ 99 Ripatti, S.............................................. 33 Ritsch, A. ............................................. 77 Rivellese, A. ........................................ 17 Rivellese, A.A. .................................... 43 Rivera, Bernardoni, E. ..................... 117 Rivera, M. ............................................ 63 Rivieccio, A. ........................................ 43 Rizos, C.V. .......................................... 86 Rizos, E.C. .......................................... 76 Rizzo, L. .............................................. 62 Rizzo, M. ................................. 45, 49, 50 Ro, H.-S. ............................................. 30 Roatti, A. ............................................. 59 Robciuc, M. ......................................... 10 Robert, L. ............................................ 52 Roberto, M. ......................................... 40 Robillard, P. ................................ 90, 108 Robin, I. ............................................. 104 Rocchiccioli, S. ................................... 62 Rochette, L. .................................. 53, 58 Rodiño-Janeiro, B.K. ......................... 57 Rodriguez, C..................................... 109 Rodríguez, C. ..................................... 92 Rodriguez, J. ...................................... 65 Rodríguez, J. ...................................... 68 Rodriguez, Leal, C. .......................... 121 Rodríguez, M.A. ................................. 36 Rodríguez, Ortega, K.D. ................. 127 Rodriguez, Padilla, J. ...................... 100 Rodríguez-Granillo, G. .................... 119 Rodríguez-Rey, J.C. .......................... 84 Roeten, M.K. ......................................... 8 Roeters, van, Lennep, J. ................... 70 Roeters, van, Lennep, J.E. ............... 51 Rog, T. ................................................. 70 Rogolino, A. .................................. 70, 95 Rogowski, J. ....................................... 57 Rogowski, O. .................................... 105 Rogoza, A........................................... 91 Roguin, N............................................ 96 Rohrer, L............................................. 71 Roig, R. ............................................... 10 Roivainen, A. ...................................... 46 Rojo, D. ............................................... 82 Romain, C. ....................................... 118 Romanelli, M.G. ................................. 67 Romanov, V. ...................................... 82 Romanov, Y. ...................................... 66 Romdhane, M. ................................. 104 Rome, S. ............................................. 31 Romero, Rodriguez, N. ............... 97, 98 Romero, Vazquianez, M. ............ 97, 98 Romero-Hidalgo, S. .......................... 99 Romero-Mamani, E.S. ...................... 35 Romier-Crouzet, B. ........................... 61 Romijn, H. ........................................... 36 Romijn, J.A. .................................. 16, 71 Ronda, N. ........................................... 71 Roquilly, A. ......................................... 76 Ros, E. ............................... 17, 26, 35, 84 Rosa, J. ............................................. 125 Rosales, R. ......................................... 74 Rosenbaum, D. .....................32, 82, 113 Rosengren, B. .................................... 10 Rosic, A. ............................................. 92 Rosing, K. ........................................... 76 Ross, R. ................................................ 9 Rossetti, M.B.................................... 116 Rossi, M. ............................................. 20 Rossignol, P. ...................................... 48 Rossomanno, S. ................................ 77 Rouanet, J.-M. ................................. 118 Rouer, M. ............................................ 38 Rouis, K. ............................................. 92 Roulot, D........................................... 105 Roussel, R. ................................. 32, 120 Rousselot, D.B. .................................. 82 Roux-Lombard, P. ............................. 47 Rovani, J.C. ...................................... 101 Roy, J. ................................................. 66 Rubanenko, O.A. ......................... 78, 92 166 Rubba, P. ............................................ 51 Rubio, Alvarez, J. ....................... 88, 125 Rubio, Taboada, C. ......................... 125 Rubtsov, P.M. ..................................... 62 Rudel, L. .............................................. 22 Rudler, M. ........................................... 32 Rudling, M. .............................. 39, 76, 83 Ruidavets, J.B. ................................. 105 Ruidavets, J.-B. .................................. 85 Ruivo, J. .............................................. 59 Ruiz-Gutiérrez, V. .............................. 35 Ruiz-Valdepeñas, Herrero, L.......... 117 Rukh, G. ............................................ 101 Ruokonen, A. ...................................... 33 Ruotolo, A. .......................................... 51 Ruotsalainen, A.-K. ............................ 30 Rusiecki, L. ....................................... 116 Russell, D............................................ 94 Rusu, R. ............................................ 106 Ryazankina, N. ................................... 64 Rybalkin, I. .......................................... 75 Rye, K.-A. ................................ 27, 31, 42 Rysz, J. ............................ 45, 49, 50, 102 Ryu, J.K. ............................................ 112 Saito, S. ........................................ 29, 55 Saito, Y. .............................................. 13 Saito, Yasushi .................................... 13 Saitoh, Y. ............................................ 95 Saka, S. .............................................. 88 Sakai, K. ............................................. 73 Sakamoto, S. ..................................... 74 Sakata, K. ..............................32, 48, 111 Sakly, M. ...................... 79, 103, 104, 119 Sako, H. ............................................ 108 Sakri, F.H............................................ 72 Saku, K. ............................................ 108 Sakuma, K. ....................................... 111 Sala, A. ............................................. 126 Sala, F......................................33, 37, 68 Salagovic, J. ....................................... 99 Sałakowski, A. ................................. 116 Sala-Newby, G.B. .............................. 59 Salari, P. ..................................45, 49, 50 Sala-Vila, A. ................................. 17, 35 Salazar-Pelaez, L.M.......................... 60 Sales, K.P.F.d. ......................... 126, 127 Salleron, J. ........................................... 7 Salles, J. ............................................. 90 Salomaa, V......................................... 33 Salvayre, R. .............................37, 38, 70 Samarut, J. ......................................... 69 Samokhodskaya, L.A. ....................... 62 Samokhodskaya, L.M. ...................... 62 Samovilova, N.................................... 66 Samoylova, E.V. ................................ 84 Sampaio, E....................................... 109 Sanak, M. ................................... 80, 127 Sanders, J.-S.F.................................. 49 Sanjib, Sahu, K. ................................. 85 Santos, I. ............................................ 80 Santos, N. ................................... 53, 116 Santos, R.D. ............................3, 42, 115 Santos, Raul D................................... 23 Santos, S. ........................................... 71 Santovito, D........................................ 90 Santtila, M. ......................................... 69 Sanyanusin, P.................................. 108 Sanz, B. .............................................. 80 Sapegin, A. ......................................... 78 S Sabaka, P. ................................ 108, 115 Sabatine, M.S. .................................... 44 Sabbadini, R. ...................................... 38 Sabench, F. ........................................ 74 Sabin, M.A. ........................................... 7 Sadeghian, H. ..................................... 46 Sadek, A............................................ 110 Saely, C. .............................................. 86 Säemann, M.D. .................................. 49 Safarova, M. ................................. 86, 87 Sagan, A. ............................................ 61 Saha, D. .............................................. 99 Saha, S.......................................... 94, 99 Sahebjam, M. ..................................... 46 Sahoudi, A. ......................................... 52 Saiki, A. ....................... 31, 109, 111, 123 Saint-Charles, F. ................................ 67 Saito, N................................................ 57 167 Saponaro, C. ...................................... 59 Saponjski, J. ....................................... 98 Saraiva, F.K. ....................................... 78 Saraste, A. .......................................... 46 Sarcina, C. ........................................ 112 Sarin, A.-P........................................... 33 Sarkadi, H. ........................................ 127 Sartini, S.............................................. 59 Sarutipaiboon, I. ......................... 99, 100 Sasaki, H........................................... 111 Sasaki, M. ......................................... 120 Sasiela, W.J........................................ 87 Sassolas, A. ............................ 31, 74, 82 Sastre, C. ............................................ 41 Sato, K........................................... 32, 47 Sato, N. ............................................... 77 Sato, Y. ................................ 31, 111, 123 Sattar, N. ......................................... 1, 20 Sattar, Naveed ................................... 20 Sattler, W. ......................................... 124 Saukko, P............................................ 46 Sawabe, M. ......................................... 62 Sawamura, T. ....................................... 6 Sawayama, Y. .................................. 124 Sayeh, A............................................ 113 Sazonova, M.A. ................................ 100 Sbrana, S. ........................................... 67 Scalissi, N. .......................................... 90 Scarlett, S. ........................................ 124 Scarpellini, E....................................... 16 Schaefer, E. .................................. 22, 91 Schaper, N. ......................................... 50 Scharin, Täng, M................................ 53 Scharnagl, H. .......................... 77, 80, 83 Scherbakova, L. ............................... 127 Scherrer, D.Z. ............................. 83, 128 Schiavino, D. .............................. 40, 107 Schibli, R. ............................................ 98 Schiopu, A. ......................................... 18 Schipf, S. ........................................... 110 Schlecht, K.......................................... 64 Schlein, C............................................ 31 Schmermund, A. ................................ 97 Schmid, M. .......................................... 41 Schmid, S.......................................... 112 Schmidt, C. ......................................... 53 Schmidt, I.............................................. 8 Schmidt, S.E. ..................................... 95 Schmidt, W. ........................................ 87 Schnecke, V. ...................................... 36 Schneider, Wolfgang......................... 11 Schonewille, M................................... 30 Schoppet, M. ...................................... 11 Schott, A.-M. ...................................... 46 Schuchardt, M. ......................... 107, 112 Schunkert, H. ..................................... 68 Schwandt, P. .....................116, 127, 128 Schwartz, C. ....................................... 22 Scott, R. ........................................ 22, 44 Scuro, A. ....................................... 65, 67 Sebzda, T. ........................................ 116 Sechi, L.A. ........................................ 115 Segarra, E. ....................................... 110 Segawa, T. ..............................32, 48, 94 Segre, A. ........................................... 115 Segura, E.................................. 109, 121 Seidlerova, J. ..................................... 96 Seleznev, E. ....................................... 60 Seljeflot, I. ................................... 55, 116 Selseth, B. .......................................... 92 Selvaraj, V. ......................................... 60 Selvarajan, K...................................... 65 Selvey, S. ........................................... 44 Semenova, A. .................................... 75 Semenovykh, P. .............................. 110 Sener, M. .......................................... 126 Senthong, V. .........................84, 99, 100 Sentieri, C........................................... 59 Seo, H.S. ...............................36, 53, 122 Seo, H.-S. ........................................... 63 Seo, J. ......................................... 89, 102 Seo, J.-B. ............................................ 78 Seo, K.W. ........................................... 59 Seppälä, I. ........................................ 101 Seres, I. ........................... 72, 80, 95, 102 Sergeeva, E.G. .................................. 99 Sergienko, I. ....................................... 75 Serhan, N. .......................................... 16 Serlie, M. ............................................ 36 Serrano, Jr, C.V. ................................ 42 168 Serre, V. .............................................. 50 Sérusclat, A. ................................. 64, 82 Settasatian, C. .............. 84, 99, 100, 108 Settasatian, N. .............. 84, 99, 100, 108 Sevin, G. ............................................. 69 Seye, C................................................ 33 Shah, A................................................ 85 Shah, C. .............................................. 87 Shah, P.K. ........................................... 81 Shahamfar, J. ..................................... 39 Shahamfar, M. .................................... 39 Shahbaz, M......................................... 86 Shakhtshneider, E. ............................ 84 Shamburek, R. ................................... 22 Shanahan, C.M. ................................. 11 Shapira, I. .......................................... 105 Sharaf, A. .......................................... 110 Sharifi, M. ............................................ 81 Sharma, P.L.......................................... 8 Sharma, S. ............................................ 8 Shattat, G. ......................................... 123 Shchelkunova, T.A. ........................... 62 Shchukin, Y......................................... 60 Shear, C.L. ........................................ 123 Shearman, C. ................................... 114 Shearston, K. ...................................... 31 Shelton, D. .......................................... 87 Sheu, W.H.-H. .................................... 71 Shi, G.-Y.............................................. 29 Shibata, M. .......................................... 55 Shibata, M.-A. ..................................... 44 Shiffman, D. ........................................ 88 Shikata, K.......................................... 124 Shima, A...................................... 78, 103 Shimizu, T. .......................................... 58 Shin, D.-G. ........................................ 117 Shin, E.K. .............................. 89, 95, 102 Shin, M.-S. .......................................... 43 Shinichi, O. ......................................... 56 Shinohara, M. ............................. 39, 120 Shirai, K. ...................... 31, 109, 111, 123 Shiri-Sverdlov, R. ................... 16, 22, 71 Shishkina, V........................................ 66 Shishkina, V.S. ................................... 67 Shpektor, A. ...................... 51, 58, 61, 64 Shuvalova, Y.A. ................................. 84 Siedlecka, D. .................................... 121 Siedlinski, M. ...................................... 60 Siekierzycka, A. ................................. 57 Siekmeier, R. ..................................... 83 Sierra, Quiroga, J. ..................... 88, 125 Siest, G. ............................................ 106 Signoretto, C. ..................................... 64 Sijbrands, E. ....................................... 70 Sijbrands, E.J. .................................... 51 Silbernagel, G. ............................. 77, 83 Sillesen, H. ......................................... 25 Silva, E. ............................................... 40 Silva, J.C.Q. ....................................... 71 Silva, S........................................ 53, 116 Silva, T. ............................................. 116 Silvennoinen, R. ................................ 33 Silvola, J. ............................................ 46 Simerzin, V.V. .............................. 78, 92 Simion, V. ........................................... 41 Simkus, G. .......................................... 40 Simonova, G. ................................... 102 Simonsen, J.A.................................... 45 Simonsen, U. ....................................... 8 Simonyi, G. ....................................... 102 Singla, D. ............................................ 11 Singparu, P. ..................................... 108 Sinisalo, J. .................................... 61, 96 Siores, E. ............................................ 38 Sironi, M. ............................................ 34 Sirtori, C.R. ................ 62, 63, 81, 96, 126 Sistonen, H....................................... 105 Sitar-Taut, A.V. ................................ 104 Sitek, B. ...............................57, 106, 121 Sivenius, J. ......................................... 39 Sjåstad, I........................................... 113 Sjöberg, S........................................... 83 Sjouke, B. ..................................... 26, 51 Skålén, K. ........................................... 53 Skalska, A. ....................................... 116 Skjelland, M........................................ 65 Skop, V. .............................................. 54 Skórka, T. ......................................... 106 Skorupan, N. .................................... 113 Skoumas, I. ........................................ 44 169 Skrbic, R.............................................. 92 Skuja, I. ..................................... 103, 106 Slagboom, P.E. .................................. 88 Slama, M. ............................................ 52 Sloan, J.J. ........................................... 10 Sluimer, J.C. ....................................... 47 Smahelova, A. .................................. 110 Smaoui, M. .................................. 85, 126 Smedby, T......................................... 106 Smirnov, A.N. ..................................... 62 Smirnova, N. ....................................... 52 Smith, D. ........................................... 126 Soares, M. ........................................... 29 Sobenin, I.A. ................... 62, 70, 71, 100 Sobotka, L. ........................................ 110 Sobrino, M. ................................. 92, 109 Södergren, A. ................................... 106 Söderlund, S. ................................ 33, 48 Soeters, M........................................... 36 Soffientini, U. .................................... 106 Sohrabi, B. .......................................... 66 Sokhanvar, S. ..................................... 91 Solheim, S. ....................................... 116 Somleva, D. ........................................ 58 Son, K.-H. ........................................... 32 Sonestedt, E. ...................................... 39 Sonmez, H. ......................................... 59 Sonoda, N. .................................. 78, 103 Soran, H. ..................................... 72, 125 Sörensen, K. ....................................... 61 Soriano, F. ........................................ 110 Sormaz, L............................................ 92 Soronen, J. ......................................... 33 Sorontila, K. ........................................ 84 Sorsa, T. .............................................. 61 Soto, Y. .......................................... 38, 68 Souza, R. .......................................... 115 Spasova, N. ........................................ 58 Specchia, C. ..................................... 100 Spina, R. ............................................. 51 Spinella, G. ......................................... 47 Sponseller, C.A. ................................. 90 Sposito, A.C.................................. 71, 78 Sprandel, M.C. ................................. 115 Sprandel, M.C.O. ............................... 72 Staels, B. ..................... 6, 28, 67, 74, 105 Staffler, G. .......................................... 87 Stafford, R. ......................................... 86 Stalenhoef, A. .................................... 51 Stalenhoef,, A. ................................... 25 Stamboul, K........................................ 53 Stan, D. ............................................... 41 Stancak, B. ......................................... 99 Stanek, V. ........................................... 99 Stangl, G.I. ......................................... 32 Stanisić, M. ....................................... 125 Stanke-Labesque, F.................. 64, 122 Staňková, B. ....................................... 82 Starzyk, J. ......................................... 127 Stathogiannis, K. ......................... 38, 45 Stead, A. ............................................. 91 Stef, M................................................. 80 Stefanadis, C. .........................38, 44, 45 Stefanovic, A. ..................................... 94 Stefanutti, C. ...................................... 81 Steg, P.G. ........................................... 52 Stehouwer, C. .................................... 50 Stein, E. .............................................. 77 Stein, E.A........................... 19, 22, 44, 87 Steinhagen-Thiessen, E. ............ 76, 80 Steinkasserer, A. ............................... 68 Steinvil, A.......................................... 105 Stender, S. ........................................... 8 Stengel, D......................................... 117 Stępień, A. ........................................ 102 Stępień, M. ....................................... 102 Stepnowska, M. ................................. 57 Sterba, M. ........................................... 57 Stergiopulos, N. ................................. 60 Sternak, M. ................................. 57, 106 Stewart, R. .......................................... 89 Stijn, C.V........................................... 103 Stitziel, N. ........................................... 50 Stocco, B. ........................................... 93 Stojakovic, T. ..................................... 80 Stojanov, M. ....................................... 94 Stojanović, M. .................................. 113 Stojkovic, I.A. ................................... 101 Stokmane, A.S. ................................ 113 Stone, P.H. ................................... 29, 55 170 Straniero, S. ........................................ 39 Strasky, Z. ............................. 57, 89, 120 Strauch, B. ........................................ 125 Stroes, E. .............................. 5, 9, 36, 42 Stroes, E.S.G. .................................... 55 Stroes, Erik ........................................... 8 Struijk, J.J. .......................................... 95 Stübiger, G.......................................... 76 Stucchi, M. ........................................ 110 Stukena, I. ................................. 103, 106 Stutler, K. ............................................ 32 Stypmann, J........................................ 76 Su, J..................................................... 63 Subhanova, I. ................................... 120 Succi, S. .............................................. 99 Suffee, N. ............................................ 57 Sugiura, T. .......................................... 94 Sugiyama, D. ........................ 77, 78, 103 Sugiyama, Y. ...................................... 42 Suh, J.-W. ........................................... 49 Suh, S.-H. ................................... 98, 112 Suh, S.Y. ..................................... 95, 102 Sulzbach, M. ................................. 76, 96 Sumino, H. .......................................... 75 Sumpio, B. ........................................ 113 Sumrit, C. .......................................... 108 Sun, L. ............................................... 120 Sun, Z. ..................................... 46, 60, 98 Sunagawa, K. ..................................... 64 Superville, A. ...................................... 74 Sur, S................................................... 60 Surakka, I. ........................................... 33 Surekha, Rani, H................................ 85 Surur, A. .............................................. 96 Sutton, A. ............................................ 57 Suwa, J................................................ 94 Suzuki, M. ............................. 58, 90, 103 Sved, I. ................................................ 56 Sviridov, D........................................... 27 Sweidan, K........................................ 123 Swergold, G.D. ............................. 26, 87 Swiader, A. ......................................... 37 Synetos, A. ................................... 38, 45 Syrycki, M. ........................................ 116 Sytdykov, I.H. ..................................... 78 Szahidewicz-Krupska, E. ............... 126 Szawrowicz-Pelka, T. ..................... 116 Szeberin, Z. ...................................... 127 Szeffler, A. .......................................... 57 Szuba, A. .................................... 38, 126 Szutowicz, A. ..................................... 73 T Tabet, F. ............................................. 27 Tabib, A. ........................................... 114 Tada, H. .............................................. 50 Taddei, A. ......................................... 108 Taghlit, R. ......................................... 119 Taguchi, N. ................................. 58, 103 Taharboucht, S. ................104, 105, 115 Tahna, T. .......................................... 116 Tailleux, A. .............................28, 74, 105 Takagi, W. .......................................... 93 Takahashi, K. ..................................... 58 Takahashi, M. .................................... 73 Takahashi, R. ............................. 58, 103 Takahashi, S. ............................... 29, 55 Takahashi, T. ..................................... 32 Takahashi, W. .................................. 127 Takai, A............................................. 106 Takamatsu, H. ........................... 35, 109 Takashima, N. .............................. 91, 95 Takata, K. ........................................... 77 Takbou, K. ........................................ 110 Takeda, K. .......................................... 93 Takhashi, M...................................... 102 Takizawa, S...................................... 127 Takkand, A. ...................................... 107 Tamakoshi, A. .................................... 48 Tamura, R. ......................................... 94 Tan, A.R. ............................................ 22 Tan, R. ................................................ 30 Tanabe, K. .......................................... 45 Tanaka, F. .................................... 32, 48 Tanaka, H. .......................................... 54 Tanaka, N. ........................................ 120 Tanaka, S. .......................................... 55 Tang, C.-K. ..............................42, 51, 71 Tang, J. ............................................... 33 171 Tang, Z.H. ........................................... 29 Tanganelli, P....................................... 61 Tangirala, R.K. ................................. 103 Tania, S. .............................................. 79 Taniguchi, H. .................................... 121 Tanno, K...................................... 48, 111 Tantipanichteerakul, K. ....... 84, 99, 100 Tapper, E. ........................................... 30 Tararak, E.M. ...................................... 67 Tarasov, K........................................... 35 Taraszkiewicz, D. ......................... 77, 85 Tarau, R. ........................................... 106 Tarhan, N. ......................................... 121 Tarugi, P.............................................. 51 Taskinen, M.-R. .................... 1, 9, 33, 48 Taskinen, Marja-Riitta ................... 9, 25 Tatsidou, P........................................ 114 Tatsumi, Y. .................................. 78, 103 Tatsuno, I. ................... 31, 109, 111, 123 Taurino, M. .............................. 28, 62, 67 Tavares, E.R....................................... 68 Tavridou, A. ........................................ 81 Tay, C. ................................................. 18 Tcimbal, S. ........................................ 127 Teerajetgul, Y. .................................. 108 Teffahi, N. ......................................... 105 Tegani, D.M. ....................................... 43 Teiger, E.............................................. 52 Teijeira, Fernandez, E. ...................... 88 Teixeira, D........................................... 49 Tejedor, D. .......................................... 80 Tellis, K.............................................. 104 Temchenko, A. ................................... 70 Terasaka, N. ....................................... 42 Tercé, F. .............................................. 75 Ternovoy, S. ....................................... 97 Terraneo, B. ........................................ 96 Tershakovec, A.M. ............................. 85 Terzis, I................................................ 82 Tesfaye, S. .......................................... 54 Tesmenitsky, Y. .................................. 62 Thabut, D. ........................................... 32 Theelen, W. ........................................ 67 Theodoropoulos, K.C. ..................... 114 Theron, H.D.T..................................... 81 Thiyagarajan, S. ................................ 86 Thomassen, A.................................... 45 Thomsen, M. ................................ 36, 55 Thorsson, O. .................................... 116 Tibolla, G. ..................................... 37, 68 Ticha, A............................................. 110 Tidone, C. ......................................... 112 Tietge, U. ............................................ 72 Tietge, U.J. ................................. 72, 103 Tietge, U.J.F. ............................... 10, 49 Tillander, P. ........................................ 92 Tillin, T. .............................. 49, 78, 89, 95 Tillmanns, H. .................................... 113 Tilly, P. ........................................ 34, 113 Tilstam, P............................................ 67 Tinelli, C. ........................................... 101 Tinoco, I. ..............................92, 109, 121 Tipping, P. .......................................... 18 Tiret, L. .......................................... 8, 117 Tiseo, G. ............................................. 31 Titkov, A. ............................................. 78 Tivesten, Å. .................................... 7, 69 Tkac, I. ................................................ 99 Toana, B. .......................................... 110 Tobayama, H. .................................... 58 Tobina, T. ........................................... 54 Toczek, J. ........................................... 99 Toda, T. .............................................. 62 Toft, E. ................................................ 95 Toftegaard, L.A. ............................... 116 Toh, B.-H. ........................................... 18 Toh, R. ...................................39, 74, 120 Tokgozoglu, L. ............................. 19, 25 Tokgozoglu, Lale ................................. 5 Toledo, E. ........................................... 35 Tölle, M. .................................... 107, 112 Tomankova, T. ................................... 62 Tomaschitz, A. ........................... 83, 101 Tomassini, J.E. .................................. 85 Tomaszewski, M. ............................... 23 Tomlinson, B. ..................................... 87 Tomoike, H. ........................................ 80 Tomono, J. ................................. 35, 109 Tonar, Z. ............................................. 28 Topchii, I. .......................................... 110 172 Toplak, H. .................................... 86, 101 Toprak, M.S. ....................................... 59 Torii, S. ................................................ 95 Toro, R. ............................... 92, 109, 121 Torqueti, M.R. ..................................... 93 Tosolini, L............................................ 50 Toth, P.P. .......................... 45, 49, 50, 85 Touat, Z. .............................................. 61 Touche, V............................................ 74 Tousoulis, D........................................ 45 Toutouzas, K. ............................... 38, 45 Touw, J. ............................................... 70 Towers, G.W....................................... 85 Tran-Dinh, A. ................................ 56, 57 Trautwein, E.A. ................................... 43 Travert, F. ........................................... 32 Trayssac, M. ....................................... 38 Trégouët, D.-A...................................... 8 Tremoli, E............................................ 34 Tretjakovs, P..................................... 103 Trichia, E. .......................................... 120 Trimech, T. .................................... 31, 76 Trimeche, A. ..................................... 103 Triolo, M. ....................................... 72, 96 Tripoten, M. ......................................... 91 Triscari, J. ........................................... 86 Tritapepe, L................................... 28, 67 Trivella, M.G. ................................ 62, 67 Trnovska, J. ........................................ 54 Trombeta, I. ...................................... 115 Trombetta, I.C. ................................. 115 Trompet, S. ......................................... 88 Troutt, J. .............................................. 50 Tsai, L.-M. ................................. 113, 114 Tsai, S.-H. ........................................... 61 Tsai, W.-C. ................................ 103, 114 Tsai, Y.-S. ........................................... 29 Tsay, P.-K. .......................................... 46 Tselepis, A. ......................... 57, 104, 114 Tselepis, A.D. ..................................... 76 Tselovalnikova, T.Y. ........................ 105 Tseng, P.-C......................................... 71 Tseng, S.-Y. ........................................ 29 Tsiamis, E. .................................... 38, 45 Tsifetaki, N. ....................................... 106 Tsigkas, G. ....................................... 114 Tsimihodimos, V. ............................... 76 Tsimikas, S. ........................................ 81 Tsiouris, S. ....................................... 106 Tsoumani, M. ................................... 114 Tsuchiya, T. ........................................ 45 Tsuda, M. ...................................... 29, 55 Tsukamoto, K. .................................. 106 Tsuneyama, K.................................. 106 Tu, Y.-L. .............................................. 51 Tufan, C. ........................................... 121 Turer, A. .............................................. 94 Turgeman, Y. ..................................... 96 Tybjærg-Hansen, A. ........... 7, 54, 55, 84 Tybjaerg-Hansen, Anne ..................... 5 Tzanetakou, I. .................................. 119 Tzavella, E.......................................... 76 U Uboldi, P. ......................... 52, 62, 94, 112 Uchida, H. ......................................... 124 Uchida, H.A. ..................................... 124 Ucieda-Somoza, R. ........................... 57 Udata, C. ...................................... 44, 87 Ueda, Y. ...............................73, 109, 122 Ueland, T. ......................................... 113 Ueno, E. .............................................. 45 Ueshima, H. ...................... 48, 77, 91, 95 Uesugi, T. ......................................... 127 Ugarte-Pedrero, X. ............................ 80 Uitti, J. ................................................. 96 Ulleryd, M.A.................................. 41, 66 Umebayasi, R. ................................. 124 Undas, A. ............................................ 39 Unhammer, Njerve, I....................... 116 Urazgildeeva, S. ................................ 78 Urazovskaya, I. .................................. 58 Urbánek, M. ........................................ 82 Urbanski, K......................................... 61 Urinov, M.B. ....................................... 89 Urpi-Sarda, M. ................................... 33 Urtane, I. ................................... 107, 113 Usta, E. ............................................. 126 173 Vanoosterhout, S............................... 22 Varbo, A. ......................................... 7, 55 Varejckova, M. ................................... 89 Varela, C..................................65, 68, 94 Varela, Casariego, C. ..................... 100 Varela, Perez, L.M. ........................... 48 Varela-Perez, L.................................. 57 Vargas-Alarcón, G....................... 77, 99 Varma, N. ........................................... 98 Varret, M. .................................26, 50, 64 Vasankari, T. 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Vercesi, A.E. .............................. 90, 101 Verdier, C. .......................................... 85 Verdugo, R. ...................................... 117 Vergely, C..................................... 53, 58 Verges, B. ........................................... 27 Vergès, B. ......................................... 104 Verhoeven, A. .................................... 70 Verhoeven, G. .................................... 69 Véricel, E. ..................................... 34, 65 Vermeer, M. ....................................... 43 Verny, M.-A. ..................................... 122 Verola, O. ........................................... 79 Veselovskaya, N. ..... 100, 102, 103, 118, 125 Vetrani, C............................................ 43 Vialettes, B. ...................................... 101 Vianello, A. ................................... 61, 93 V Vacula, I. ............................................. 79 Vagionas, I. 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71 Vongpromek, R.................................. 70 Vorobjov, R. ..................................... 107 Vorobjova, E. ................................... 107 Vorobyev, R.I. ................... 78, 91, 92, 97 Vorobyeva, E.N. ............... 78, 91, 92, 97 Vorrsjö, E. ..................................... 31, 75 Voss, J.C. ........................................... 73 Voss, S.S. ........................................... 32 Voulgari, C...............................54, 82, 95 Vovchenko, M. ................................... 77 Vozzi, F. .............................................. 67 Vrablik, M............................................ 99 Vrablík, Michal ................................... 18 Vranckx, R. ....................................... 114 Vreugdenhil, A.C.E. .......................... 22 Vrieze, A. ............................................ 36 Vrints, C. ........................................... 104 Vromman, A. ...................................... 60 Vučić, M. 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A................................................ 8 Zekri, S. ............................. 104, 105, 115 Zelina, M. .................................. 108, 115 Zelinka, T. ......................................... 125 Zeller, M. ....................................... 53, 58 Zeller, T. ........................................ 8, 117 Zemankova, L............................. 89, 120 Zerbinati, C. ........................................ 60 Zernecke, A. ....................................... 47 Zerrad, A. .......................................... 108 Zhai, Y.Z............................................ 118 Zhang, F. ............................................. 33 Zhang, H. ............................................ 16 Zhang, J. ............................................. 56 Zhang, J.-J. ......................................... 51 Zhang, L. ............................................. 30 Zhang, R. ............................................ 56 Zhang, T. 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............................................ 68 Zmojdzian, M. .................................. 122 Zo, J.-H. .............................................. 78 Zoetendal, E. ...................................... 36 Zoroufian, A........................................ 46 Zsíros, N. .......................................... 102 Zulj, M. ................................................ 93 Zulkafli, N............................................ 58 Zyatenkova, E. ................................... 88 178