Celebrating Milestones
Transcription
Celebrating Milestones
annual report 2005-2006 Celebrating Milestones a new name, same tradition of excellence. u n i v e r s i t y o f w i s c o n s i n p a u l p. c a r b o n e c o m p r e h e n s i v e c a n c e r c e n t e r message from the director Celebrating re s earch. e ducation . tr e atm e nt. h o pe. Dear Friends, This past year, we celebrated a momentous milestone in the history of the Cancer Center. We officially became the University of Wisconsin Paul P. Carbone Comprehensive Cancer Center. Additionally, the Cancer Center’s central research tower was named the Harold P. Rusch Translational Research Tower. welcome With unparalleled leadership, Paul P. Carbone and Harold P. Rusch made cancer research and patient care at the University of Wisconsin their lifework. Collectively, they established a hard-earned, worldwide reputation for innovative cancer research and treatment at the University of Wisconsin. The work of the two men set a foundation for the Cancer Center’s evolution into the 21st century— integrating basic science and clinical research more quickly into new patient care options. In the pages that follow, you will read more about both Dr. Carbone and Dr. Rusch and the legacies they have left. Decades of work by distinguished Cancer Center faculty have laid the groundwork for improvements in health care for the people of Wisconsin and beyond. At the Cancer Center, the science of medicine and art of compassion are carefully balanced. By creatively blending the unique expertise and resources of many across the UW-Madison campus, the Cancer Center achieves a rich synergy of research, patient care, community service and education. In this report, you’ll meet some of our researchers, physicians and staff—people whose work continues to create milestones within the Cancer Center’s history. On behalf of our faculty and the individuals and families who benefit from their work, I thank you for your support of the University of Wisconsin Paul P. Carbone Comprehensive Cancer Center. Sincerely, George Wilding, MD Director UW Paul P. Carbone Comprehensive Cancer Center Anderson Professor of Medicine “Something Attempted, Something Done” Celebrating harol d P. R usch, M D ( 1 9 0 8 - 1 9 8 8 ) harold P. Rusch, MD time,” says UW Paul P. Carbone Comprehensive Cancer Center director, George Wilding, MD. “His was a remarkable achievement; he developed not one cancer center, but two. People talk about translational research now, but Rusch was working toward creating complementary research and clinical programs back in the 1930s.” “Something Attempted, Something Done” Throughout his long and productive life, Harold P. Rusch (’31 BA ’33 MD) seems to have quietly and effectively embraced that sentiment. He chose it as the title of his autobiography and as a philosophy of life. The man, who seven decades ago began a career dedicated to understanding and conquering cancer, left an indelible mark on medical science at the University of Wisconsin and the nation. A basic scientist first, his contributions to the study and treatment of cancer were balanced by an equal genius in building and administering the first research center in the nation dedicated to studying the causes and potential cures for cancer. Ultimately, he established two world-class cancer centers on the UW-Madison campus. “Harold Rusch was a visionary, a man decades ahead of his “We didn’t realize he was important,” remembers his daughter, Carolyn Rusch Schlotthauer, of Florida, “he was just ‘Daddy.’ He was a kind, nurturing father and grandfather to Kristina and William. We were all so very lucky to have him.” Rusch was a Wisconsin native who grew up in Merrill, about 20 miles north of Wausau. In his memoirs, he credits his interest in medicine to a boyhood appendectomy that launched a short career as surgeon to his mother’s vegetables. That early experience, and the influence of his uncle, a Milwaukee physician, led him to college and medical school at the University of Wisconsin-Madison. “He was a wonderful, gentle, knowledgeable person,” says his second wife and widow, Louise Van Wart Rusch, “and an excellent judge of people.” While still a medical student, Rusch demonstrated an innate interest in knowing more about why certain treatments worked. In 1934, a former professor invited him to teach physiology and establish a research laboratory. The offer forever shifted Rusch’s career away from practicing medicine and toward medical discovery. Also in 1934, the medical school received a bequest of nearly half a million dollars to support “fundamental studies regarding the nature and cure of cancer.” The gift, coupled a year later by one from the estate of Michael McArdle, launched the school’s cancer program, and Harold Rusch’s life work. “Harold Rusch was a humble yet forthright man who was not afraid to speak his mind,” says UW professor emeritus Henry Pitot, MD, PhD, who succeeded Rusch as McArdle director. “His goal was to significantly advance our knowledge and control of cancer in human patients. To realize his goal Rusch brought together in a single interactive laboratory some of the brightest young minds in cancer research. “While he always discussed with and urged his colleagues to develop their studies as applied to human cancer, it wasn’t until the UW Clinical Cancer Center (later known as the UW Comprehensive Cancer Center) was established that he came closer to his life’s dream.” At age 30 and only four years out of medical school, Rusch worked with the state architect to design the first McArdle Laboratory, a wing of the Medical Sciences Center, and, 25 years later, he helped design the existing McArdle Laboratory. “McArdle was his biggest pride and joy,” says his step-daughter, Virginia Francis of Middleton, Wisconsin. “He was a natural teacher—he always found a way to enrich any experience—always wanted to share his knowledge, but he lived and breathed his work.” Rusch is also credited with creating an exceptional intellectual environment at UW, one which encouraged talented researchers and facilitated interactions that sparked new ways of studying a problem. It was Rusch who recognized the potential of young McArdle researchers such as Nobel Prize-winner Howard Temin, PhD, whose enzyme research helped to explain how retroviruses cause cancer. According to UW professor of oncology and medical genetics Harold Rusch continued his cancer research while directing Wisconsin’s two leading cancer centers. William F. Dove, PhD, one of six Rusch faculty hires who later became members of the National Academy of Sciences, Rusch “combined a gentle demeanor with decisive action. This first enabled him to build a rapport as a mentor of many young investigators, each driven by a creative ego. The second allowed him to connect with national leaders, such as Congressman Melvin Laird, to crystallize legislation that promoted cancer research funding.” Throughout his life Rusch served on panels and commissions designed to set national and international cancer policy. He received numerous professional awards and was active in many cancer-related organizations, including the American Cancer Society. hope Rusch became the inaugural director of the McArdle Laboratory for Cancer Research in 1940. It was the first basic science cancer center in an academic institution in the United States and from the beginning it was committed to understanding the causes of cancer and to training exceptional basic science researchers. Rusch was a dedicated scientist. In 1941 he identified the wavelength of ultraviolet light that produces skin cancer. Subsequent studies demonstrated a link between obesity and cancer, and his belief that cancer was caused by a series of biochemical changes became the basis for studies on the stages of tumor formation. known as the UW Comprehensive Cancer Center (UWCCC). The move from basic science research to the treatment side of the cancer fight was simply a continuation of the same overarching vision. A year later, the National Cancer Institute recognized the UWCCC as one of the nation’s first university-based comprehensive cancer centers. Rusch hired his successor at the UWCCC, Paul P. Carbone, MD in 1976, and in 1979 retired from UW-Madison. He continued to be active in professional activities, frequently coming into his office when he and Louise weren’t traveling throughout the world visiting family and colleagues. In 1988 Harold Rusch succumbed to the disease that he spent a lifetime trying to understand and conquer. In 1972 Rusch founded and became the first director of UW Clinical Cancer Center, later A founding father of cancer research and treatment Celebrating Paul P. carbone, MD Paul P. C arbon e , M D ( 1 9 3 1 - 2 0 0 2 ) “Paul Carbone is recognized as a genius in his field. He was truly a founding father of cancer research and treatment. At Wisconsin he laid a solid foundation upon which we continue to build today.” –George Wilding, MD When Paul Carbone arrived at the University of Wisconsin-Madison in 1976, he was already a wellrespected and award-winning cancer researcher and physician. He came to the UW Clinical Cancer Center—which under his leadership developed into the internationally renowned UW Comprehensive Cancer Center— during a period of transition. The UWCCC had been created just three years earlier by Harold P. Rusch, MD, founder of UW’s McArdle Laboratory for Cancer Research, and Rusch was looking for a successor. In Carbone, Rusch found an enthusiastic, talented leader with vision, dedication to research and profound respect and concern for people with cancer. In his memoir, Rusch praised Carbone’s “excellent credentials and wide experience in both general medicine and cancer chemotherapy,” and his “deep concern for the problems and welfare of patients.” Rusch’s thought was to establish an exemplary clinical program to complement the already recognized basic oncology research program at the McArdle Lab, and Carbone was the man he wanted to lead clinical oncology research at the UW. “He was very passionate about his work and making lives better,” according to his daughter, physician Kathryn Carbone, MD ’83. “He talked constantly about the quality of life and the need for people to fight cancer—even at a time when it was common to send those with a diagnosis of cancer home to die.” Not surprisingly, as chairman of the Breast Cancer Task Force, he created a vision for research policy of adjuvant chemotherapy for people with early-stage breast cancer. Says George Wilding, MD, director of the UW Paul P. Carbone Comprehensive Cancer Center, “Paul Carbone is recognized as a genius in his field. He was truly a founding father of cancer research and treatment. At Wisconsin he laid a solid foundation upon which we continue to build today.” His colleagues recognized Carbone’s dedication and medical acumen. He received countless national and international awards throughout his lifetime, including the prestigious Lasker Award for Medicine, generally considered America’s Nobel Prize, for combination chemotherapy for Hodgkin’s Lymphoma, demonstrating that cancer often can be a successfully treated disease. A New York native, Carbone came to the UW after retiring from the Commissioned Corps as Chief of the Medical Branch at the National Cancer Institute (NCI), the culmination of an 18-year career in the Public Health Service. While at the NCI, Carbone started his 20-year service as chair of the Eastern Cooperative Oncology Group (ECOG), leading that organization to become one of the nation’s most respected clinical research groups, with studies conducted in more than 300 hospitals and medical schools. He was a founding member and president of the American Society of Clinical Oncology and president of the American Association for Cancer Research. As the editor-in-chief of major oncology journals and author of nearly 400 publications, Carbone was influential in setting research policy, both in the U.S. and abroad. In 1994, Steven T. Rosen, MD, then editor of Contemporary Oncology, described Carbone as “... a giant in our field, a pioneer in clinical investigation and a role model to scores of academicians involved in cancer research.” Outside of his cancer world, Carbone rode his bicycle, sailed, had a garden and liked to travel. But, says daughter Kathy, golf was his passion. “He loved his golf, even confessing one day that the real reason he was late to dinner was that he stopped for 9 holes of golf after returning from a trip!” Carbone and his wife Mary had seven children—three are physicians, one is an attorney and three hold MBAs—and 16 grandchildren. Paul Carbone was a beloved clinician, fondly remembered by both his patients and colleagues. When son Matthew Carbone recalls his father, he says “He did what he did because he loved to do it, not for the recognition or money. As I grew up I was, and continue to be, so proud to meet his patients and students and learn of his achievements.” “He is always in my head. I feel his positive advice with me every time I make a significant decision.” Matt describes Carbone’s lasting legacies as his students and his children. “Professionally, he was a great teacher who left behind wonderful legacies at the UW but also in Taiwan, Singapore, Africa and China. Personally, he was perhaps most proud of the accomplishments of his children.” hope Carbone’s scientific legacy is enormous. A member of the first certifying committee for the American Board of Internal Medicine for Medical Oncology, he helped write the first exam to set the standards for medical oncologists in the United States. He was also the inspiration and mentor for hundreds of cancer specialists who today continue to advance cancer discovery and care, including oncology treatment centers and training programs in Uganda, Taiwan and Singapore. Carbone was responsible for instituting medical oncology rotations through hospice care programs, and was a devoted supporter of the Don and Marilyn Anderson Hospice Center in Fitchburg, Wisconsin. Even after he officially retired in 1997, Carbone averaged 35 hours a week back in the UW Hospital and Clinics’ “K tower,” continuing drug research, guiding young researchers and caring for patients. passionate, intelligent, sensitive and visionary man. “He did what he did because he loved to do it, not for the recognition or money. As I grew up I was, and continue to be, so proud to meet his patients and students and learn of his achievements.” –Matthew Carbone When he died unexpectedly in 2002, Carbone was still deeply involved in the subject that shaped his life—he was in the Far East, helping develop a comprehensive cancer program at the National University of Singapore...and playing golf. Kathy’s wish for her father is that his lasting memory for both his family and the world, be that he was an honorable, dedicated, Founders’Day Celebration Honoring the legacies of Dr. Harold P. Rusch and Dr. Paul P. Carbone Tuesday, September 26, 2006 Overture Center for the Arts, Madison On September 26, 2006 the Cancer Center celebrated its world-renowned role in cancer research and treatment by honoring two revered leaders. The Cancer Center was named the UW Paul P. Carbone Comprehensive Cancer Center and the center’s central research tower as the Harold Rusch Translational Research Tower. Founders’ Day event More than 600 individuals gathered for the Founders’ Day Celebration at the Overture Center for the Arts in Madison to recognize both Dr. Paul P. Carbone and Dr. Harold Rusch. Top right photo:The Honorable Jim Doyle, Governor of Wisconsin, and his wife Jessica participated in the program honoring Carbone and Rusch. They are joined by Cancer Center Director George Wilding, MD (center), his wife Helen and daughter Amanda. Bottom right photo: Jon McGlocklin, President of Midwest Athletes Against Childhood Cancer presents Dr. Wilding with a $3.5 million gift in support of childhood cancer research. Ev e nt S pon sors The University of Wisconsin Paul P. Carbone Comprehensive Cancer Center gratefully acknowledges the following supporters of the Founders’ Day Celebration: Premier Midwest Athletes Against Childhood Cancer Sponsor Paul P. Carbone, MD Memorial Foundation Department of Human Oncology, UW School of Medicine and Public Health Department of Surgery, UW School of Medicine and Public Health Partner Robert W. Baird & Co. Incorporated UW Health (UW Hospital and Clinics and UW Medical Foundation) Department of Radiology, UW School of Medicine and Public Health Department of Medicine, UW School of Medicine and Public Health Celebrating the legacy of Dr. Harold Rusch were several family members, including (left to right): Marge Senn, Roger Senn, Lynn Rusch, Don Van Wart, Gino Iavarone, Will Schlotthauer, Christina Schlotthauer, Kris Iavarone, Adam Schulz, Carolyn Schlotthauer, Virginia Francis, Louise Rusch, Lise Pollock, George Schlotthauer, George Francis, Elliot Schulz and Elise Freed-Brown. The family of Dr. Paul P. Carbone celebrated the renaming of UW Comprehensive Cancer Center in his honor. They are, clockwise starting from upper left, David Carbone, Marybeth Catanzaro, Kathryn Carbone, Matthew Carbone, Paul Carbone, Mary Carbone, Kimberly Carbone and Bobbi Traber. Hope Dr. Wilding welcomes Tommi Thompson (left), Dominick Carbone, brother of the late Dr. Paul P. Carbone, and Sue Ann and Tommy Thompson to the Founders’ Day Celebration. Supporter M&I Bank RBC Reiman Foundation, Inc. Winston & Strawn, LLP Hematology/Oncology Section, Department of Medicine, UW School of Medicine and Public Health Supporter Department of Anesthesiology, UW School of Medicine and Public Health Department of Dermatology, UW School of Medicine and Public Health Department of Obstetrics and Gynecology, UW School of Medicine and Public Health Donna Sollenberger, President and CEO of UW Hospital and Clinics was in attendance with David Entwistle, Chief Operating Officer of UW Hospital and Clinics (left) and Jeffrey Grossman, MD, President and Chief Executive Officer of the University of Wisconsin Medical Foundation. Associate American Association of Cancer Research (AACR) American Society of Clinical Oncology (ASCO) Foley & Lardner, LLP Friend Boardman Law Firm LLP Michael Best & Friedrich, LLP Stark Investments Venture Investors, LLC Department of Ophthalmology, UW School of Medicine and Public Health F. Michael Hoffmann, PhD, is the faculty advisor for the Cancer Center’s Small Molecule Screening Facility. Milestone Sma l l Mo l ecul e S cre e n i ng Faci l ity F. Michael Hoffmann, PhD is the faculty advisor for the Small Molecule Screening Facility. The facility was established with funding from the UW Keck Center for Chemical Genomics and the UW Paul P. Carbone Comprehensive Cancer Center (UWCCC). research How has your career path led to your current work? I first studied chemistry, then biochemistry, then genetics. I came to McArdle in 1984 and did genetics research on fruit flies until about six years ago. Now, as faculty advisor at the Small Molecule Screening Facility (SMSF), I’m combining all those interests—small molecule screening is sometimes called “chemical genetics.” What are small molecules? A small molecule is a chemical; it can be either a synthetic or a natural product. It is small only in comparison with larger biological molecules, such as proteins, which tend to be hundreds of times bigger. Why are they important to cancer research? Small molecules are important because some of them have the ability to interact with, or bind with, a biological molecule and change its activity, to either inhibit it or activate it. They become tools for learning more about the function of that molecule. Also, if we can demonstrate that a small molecule can affect a particular protein, it may open the door to developing a drug that could work on that target protein. Why was it important to establish the Keck–UWCCC Small Molecule Screening Facility at the UW? Small molecule screening is a basic research tool with very broad application. It’s been going on for a long time in industry, but it’s only fairly recently that the thousands of chemical compounds and the technology—such as liquidhandling robots—have become accessible to academic centers. When the facility opened in 2003, it was probably one of only six in the country. How does screening work? We have a library of more than 60,000 chemical compounds, in all different shapes, sizes and colors. And for any particular assay, or trial, we add them one at a time and ask, does this have an effect? It’s kind of the old needle in the haystack; we’re looking for one compound in 60,000 that has an effect on an individual protein or distinct cell line. In addition to our chemical library, there’s a lot of great chemistry on campus. UW chemists bring us novel compounds they’ve created and ask us to determine if any of them are effective against cancer cells. So, we set up over a dozen cancer cell lines—breast and prostate and ovarian and lung, for example. We can screen a couple of hundred novel compounds, indicating to the chemist if one is more potent or one has some specificity for a cancer type. That helps them decide whether or not to do more work with a specific compound. What is the Lead Discovery Initiative? In September, the Wisconsin Alumni Research Foundation (WARF) announced the Lead Discovery Initiative, which can provide funding for assays on new compounds for chemists, or for screening our collections of compounds for biologists. A committee reviews proposals from around campus on a monthly basis, and supports both types of research. Does the SMSF run assays related to diseases besides cancer? Yes. As with any of the UWCCC core facilities, the SMSF is open to anyone on campus; it is a terrific contribution that the Cancer Center makes to the entire research effort on campus. We are starting to do more work with viruses, and with infectious disease and heart disease targets. michael F. Hoffmann, PHD photo Caption goes here kathy category Schell He adli n e go es he re 10 Kathy Schell is the supervisor of the UW Paul P. Carbone Comprehensive Cancer Center’s Flow Cytometry Facility. Milestone Fl ow C ytometry Facil ity In 1988 the UWCCC established the Flow Cytometry Facility to serve the many research needs of its members. As the demand for its services has increased, both within the Cancer Center and on campus, the facility has expanded offerings to cover many cancer and non-cancer areas of biological research. For more than 18 years, Kathy Schell has worked in the Flow Cytometry Facility. How do campus researchers use the Cancer Center’s Flow Cytometry Facility? The technology has applications across all areas of biology. We offer technical assistance and cellular analysis to investigators in more than 30 campus departments. We have experience with many applications and are involved in developing many others. Our users have access to all of this experience. What has inspired you the most during the course of your career? My family, and a few great teachers who were responsible for my interest in science. However, the research community here is a never-ending source of inspiration when they work with us to develop new methods and creative ways to use our technology. What would people be surprised to learn about your years at the Cancer Center? I got this job by accident. What are the challenges for people involved in your research? The biggest challenge will be securing funding to maintain the cutting edge technology we currently enjoy. There’s been a recent explosion in technology development, and a cytometer purchased for $500,000 five years ago will be out-of-date in the next five years without significant upgrades or replacements. research Name What is flow cytometry? Flow cytometry measures multiple molecules in or on single cells at a very rapid rate in a liquid environment. A basic flow cytometer contains a laser on one side of a flow cell and a light scatter detector on the opposite side. What sets the UWCCC Flow Cytometry Facility apart from similar facilities in the country? Through the Cancer Center’s support, we are able to maintain state-of-the-art instrumentation and have been successful in obtaining National Institutes of Health funding for major instrument purchases. We are educating our staff by sending them to national and international classes and meetings. As a result, the facility has a broad spectrum of equipment and the knowledgeable staff to support any requirements our research community might have. We are among a handful of core facilities with this breadth of technology and experience. Where do you see flow cytometry in the future? Being able to examine a single cell with its many molecular components is the power of flow cytometry; it will enable scientists to make major strides in finding cures and answers for incurable diseases. Flow cytometry and fluorescent image technology will be essential in determining why some cancers are more aggressive than others; they are likely to dissect the immune response to world plagues like AIDS, leading to an effective vaccine. 11 11 David Gustafson, PhD, led the team that developed CHESS at UW-Madison’s Center for Health Systems Research and Analysis. Milestone CH E S S University of Wisconsin professor emeritus David Gustafson launched the development of the Comprehensive Health Enhancement Support System (CHESS), a computer-based system of integrated services designed to help individuals cope with a health crisis or medical concern. education What inspired your research into using technology-based health education and support in helping cancer patients? I have always been interested in how people make health-related decisions. The first work I did was in mental health, using computers as a tool to help people at risk for suicide; then to help middle and high school students be more successful at school. I’ve always felt that giving people accurate, up-to-date information, tools they can use to help make decisions, and the support they need, is critical to making good choices. In 1990, this need for information came crashing home when my wife was diagnosed with breast cancer. Here I was, working in health decision-making my entire career, and yet when that diagnosis came, it was as if we were both lost and unable to think clearly. We had so many questions—but didn’t even know what questions to ask. We wanted to know the best course of treatment based on all the scientific evidence out there, but got different points of view from different providers. 12 And beyond the scientific information, we needed practical information, like how and when to tell our children about this. It was a very, very difficult time. Once my wife and I got through this experience, several of us started working on a computer system specifically for women with breast cancer and their families called CHESS—the Comprehensive Health Enhancement Support System. It has now been used by thousands of women, and just last year it was translated into Spanish. about who will use and benefit from such systems. For example, our work has demonstrated that all kinds of people—regardless of income, education or experience with computers—will use these systems if given the opportunity. We’ve also found that our program can enhance the doctorpatient relationship. Oncologists have consistently told us their patients come in with more relevant questions and have better clinical visits when they have access to high-quality information and support. Are there other CHESS programs besides the breast cancer module? We have CHESS programs on prostate and lung cancer, which include an additional emphasis on caregivers. We also have a tobacco cessation module and are developing a module for parents with a child going through a bone marrow transplant. What is the future for using new media technology to improve outcomes in cancer care? There are so many ways that it can go. One of the biggest issues is making technology usable when people need it. Currently, many people use CHESS from laptops—so it is somewhat portable. But we need to have it even more mobile, using devices such as Smart Phones which are part of everyday life for so many people now. How has CHESS research affected the way cancer patients receive care? Numerous clinical trials have demonstrated that CHESS can improve a variety of outcomes, when coping with a cancer diagnosis. These include quality of life, emotional well being and social support. This work has inspired innovative internet-based programs to help people facing other health crises as well. I think our work has also challenged some early stereotypes We need people to get the information, support and coaching they need—where ever they are, instantaneously. So people waiting for test results won’t need to sit by the phone, they can get them through a web-enabled phone as soon as they are ready. We need to make technology so easy to use that it really is part of everyday life—making a real difference whenever and wherever people need it. david Gustafson, PHD 13 13 photo Caption goes here judy De muth, category RN, MS He adli n e go es he re 14 UW Cancer Clinics Manager Judy De Muth, RN, MS will be retiring this year after more than 30 years in cancer care. Milestone C ompr eh e nsive C a nce r C ar e Since 1974, Judy De Muth has been actively involved in cancer care and all but four of those years have been in management. Change has remained a constant for De Muth; she has seen many changes in health care delivery, drug development and technology throughout her career. What sets the UW apart from other cancer centers in treating cancer patients? First, we are a comprehensive cancer center, providing patients with state-of-the-art clinical trials, bench research, teaching and clinical care. For instance, it is exciting to have participated in a clinical trial for a drug that was Can you tell us what you have learned during your time at UW? From a nurse manager perspective, I have learned about the various aspects of managing an area that has grown from one to five clinics. With that came opportunities to develop budgeting skills, mentor staff, plan and manage four remodeling projects. I’ve learned how to derive satisfaction for patient care through the hard work and dedication of the clinic staff. From a nurse perspective, I’ve learned about courage, family relations and how serous illness can adversely affect a family or pull a family together. I always admire the hope and strength of will our patients display. I believe I have learned many life lessons from our patients. You have seen many cancer patients over the years. Are there any particular memories that you wish to share? I have been touched by many patients and families. There have been tears of joy and sadness over the years. Once, I ran into the mother of one of my former patients and she introduced me as the patient’s nurse as she gave me a big hug. Recently, a patient stopped me in our clinic waiting room. She said she’d been wanting to stop and tell me that 10 years ago—when she was first diagnosed and about to undergo chemotherapy—she was so distraught and I had taken her into a room and listened to her fears and concerns. She explained that I had been so helpful to her and she wanted me to know that. It meant so much to me to know that I had made a difference for someone. treatment Name How has the way cancer care is provided evolved throughout your career? There have been many changes during my 30 years in cancer care. For example, the change from administering chemotherapy on the inpatient units to an outpatient setting has greatly increased. Today, most treatment happens in the clinic. The number of available chemotherapeutic agents has grown tremendously. We now have more agents and more drug combinations available to treat a wide variety of cancers. In the area of supportive care, we now have better anti-emetic agents, growth factors that support the bone marrow, as well as increased social work, health psychology, nutrition and integrative medicine support services. developed here and then see that drug or drug combination become part of standard therapy. What is your one wish as cancer research and treatment advances in the next few years? There are really two areas that I would like to see expanded. One is to continue to educate society about the risks of cancer and how people can reduce their risks by taking personal responsibility for their health. Another is to have better access to cancer education, care and clinical trials for underserved populations. 15 Do you have wonderful retirement plans? I am excited to be able to spend more time with my family. My girls live out of state and I would like to be able to visit them more often. My husband travels a lot and I am looking forward to accompanying him on some of these trips. With my passion for cooking, I am looking to take more advance classes. And lastly, I would like to explore my options for volunteer work. 15 Rebecca Marnocha, PharmD, leads the Pharmaceutical Research Center. Milestone Pharmace utical R e s earch C e nt e r The Pharmaceutical Research Center, under the direction of Rebecca Marnocha, PharmD, ensures the safe and ethical provision of investigational study drugs to research subjects enrolled in Cancer Center clinical trials. education Can you explain the role of the Pharmaceutical Research Center (PRC)? The mission of the PRC is to ensure investigational and study drugs are safely and ethically provided to people enrolled in clinical drug trials within UW Hospital and Clinics (UWHC) and the Cancer Center. We also educate and train health care providers about investigational drugs, clinical drug study design integrity and human research regulation; ensure drug research protocols proceed optimally through the UWHC medication use system and in accordance with all federal, state, institutional and sponsor regulations; and continually refine and expand our services to meet the needs of the research community. To accomplish its goals, the PRC offers study design assistance, manages all aspects of drug handling and accountability, creates informational drug monographs for health care providers, engages in training and quality assurance activities and provides a 24-hour a day, 7-day a week research pharmacist on-call service. 16 While the PRC program serves all clinical drug researchers at UWHC, its association with the Cancer Center is unique in its level of commitment, formal relationship and in the breadth and depth of its services. PRC actively participates in the Cancer Center’s Experimental Therapeutics research program, is involved with numerous Cancer Center committees, supports the Cancer Center’s drug list database, provides drug distribution services for qualifying studies within the Wisconsin Oncology Network program and serves as a liaison to the Cancer Center for research infrastructure and UWHC issues. What sets the PRC apart from similar facilities in the United States? A quality pharmacy-based research support program is an integral factor to any institution’s success in conducting clinical drug research. The PRC program at UWHC has been identified as a model service by many external agencies and has been instrumental in creating UW’s successful research infrastructure environment. Compared to many academic research centers, the PRC program is among the largest but its size is not what makes it unique. Rather, it has been the integration of the PRC program within the UW clinical research infrastructure, including the Cancer Center and the level of UWHC institutional support that has made the difference. Please tell us more about your new role within UW School of Medicine and Public Health. The Director of Clinical Research position was created to make better connections between the School of Medicine and Public Health (SMPH), UWHC and UW Medical Foundation (UWMF) and to advance clinical research at UW. I am excited about serving in this new capacity and to be a change agent for the global infrastructure. I will be responsible for fostering positive working relationships, optimizing operations, assuring effective and efficient connections and unifying strategic plans within the clinical research infrastructure of the SMPH, UWHC and UWMF. I’ll be working to achieve a center of excellence by providing a safe, ethical, regulatory compliant, resource sensitive, fiscally responsible, efficient and effective clinical research environment. I will also be an infrastructure consultant to the Health Sciences Institutional Review Board, the Office of Clinical Trials and the General Clinical Research Center and a formal liaison to the Cancer Center. rebecca Marnocha, Pharmd 17 17 photo Caption goes here Bill Dove william Dove, category PHD He adli n e go es he re 18 William F. Dove, PhD, is the program leader of the Cancer Genetics program. Milestone C anc er G e n etics William F. Dove, PhD, of the McArdle Laboratory for Cancer Research, leads the Cancer Genetics program, which involves research in 24 different labs on the UW-Madison campus. The basic science of genetics seeks the connections between molecules that carry out a process, and a phenotype, or the expression of that process. Every gene can be thought of in terms of the molecule that it codes for. When you have a mutated gene, you therefore have a mutated molecule and so a changed phenotype—in this case the cancer phenotype. Can you give an example of this type of research? In my lab, our research starts with mutations in certain key functions called “gatekeepers.” So we have both a mouse family and a rat family that were developed here at the university which have mutations in the How might such an understanding lead to treatments? Sometimes we’ll see that we have a more severe cancer when the mutation inactivates the molecule. This is called loss of function. Then we say, well, perhaps if we supply that function, we can make it better. This gives us a very concrete lead for a kind of therapy that could be developed. For instance, we’ve found there’s an enzyme, a phospholipase, that’s secreted within the colon, but not from the tumor, from neighboring healthy cells. When it’s active, tumors grow more slowly. So perhaps when this product is diminished, replacing it could prove therapeutic. Why is colon cancer so common? The intestinal epithelium is the most actively self-renewing tissue in a mammal. Every week we have a new intestine, in terms of the cells that are present. A very active turnover means a lot of potential for error. There are a number of protective mechanisms to keep it from developing growths, but these mechanisms aren’t perfect. So colon cancer is among the most common cancers. But in terms of the numbers of cell divisions that go on, it’s quite remarkable that colon cancer doesn’t develop every year in every person. What might such research mean for early detection? We are identifying molecules that are associated with the tumors and accumulate in various body fluids, including blood serum. These molecules give us a highly sensitive way of screening for tumor-bearing animals versus normal animals. research Name You’re the director of the Cancer Genetics program. What is genetics? You may read about scientists finding a gene for colon cancer, or for breast cancer. What that really means is they’ve found a gene where a mutation makes a big difference. But it doesn’t mean that breast cancer involves only that single gene. A cancer involves many genes, perhaps thousands of genes. central gatekeeper for colon cancer. When these animals develop intestinal tumors, we can study how other genes and environmental factors interact with the disease. What changes make the cancer more severe, and what changes make it better? Right now there are not enough trained gastroenterologists to handle colonoscopies for the whole population over 50. Since people give blood samples when they have a physical, if there were a blood serum-based test, it might become a less invasive form of early detection. 19 Is there anything you want to add about this program? Research across the Cancer Genetics program is drawn together by the intersection between classical genetics, comprehensive molecular analysis of genotype and phenotype, and biostatistics. Finally, at the end of the day, research findings must be tested at the human level. The Healthy Wisconsin initiatives of our School of Medicine and Public Health are very important in this. 19 Dr. Brad Kahl is the Director of the UW Lymphoma Service and Clinical Research Director for Hematologic Malignancies. Milestone Cli n ical R es earch As a hematologist treating many patients with lymphoma, Brad Kahl, MD, finds his field infinitely fulfilling. A clinical researcher searching for new and better cancer treatments, he can look his patients in the eye and tell them that he has a very personal commitment to improving their condition. treatment How did you decide to become a hematologist-oncologist? My father died of chronic myelogenous leukemia (CML) when I was 12. Obviously, that had a big effect on me. I went to medical school unsure of what kind of doctor I wanted to become. During the second year, we covered hematology, the study of blood disorders, and it all clicked. After that, there was never a doubt. What sets the UW Paul P. Carbone Comprehensive Cancer Center apart in providing cancer care? Without a doubt, the cutting edge research and treatments combined with compassionate, individualized care that we offer. I have seen many patients seek second opinions at other major cancer centers and they almost always come back, talking about how lucky they feel to have the Cancer Center in their backyard. 20 Are there any groundbreaking initiatives on the horizon in hematology? Historically, multiple myeloma was the worst possible blood cancer diagnosis. However, in the past five years there have been several new treatments developed for myeloma and several more are in development. No single treatment may qualify as a true breakthrough, but when all of the new options are considered together, the progress in myeloma is truly impressive. Tell us more about your clinical research. I focus on developing new treatments for patients with lymphoma, which is cancer of the lymphatic system. There are approximately 40 different kinds of lymphomas, so I find it a very challenging area. Much of my research has centered on developing monoclonal antibody therapy, which has far fewer side effects than chemotherapy. What challenges lie ahead for individuals involved in your research? Our understanding of what makes cancer cells tick is outpacing our ability to apply that knowledge to help cancer patients. There are a multitude of reasons why. The challenge is to take what is learned in the laboratory and rapidly apply this knowledge to benefit our patients. What will the future hold for cancer research? The future lies in translating discoveries in molecular medicine into personalized cancer care. We are going to be able to test tumor cells from two patients who appear to have the same kind of cancer and see that the cancers are actually quite different at the molecular level. Then we will be able to select targeted agents tailored to each individual. The result will be better outcomes with fewer side effects. It is going to be exciting to see this unfold. Is there anything else you would like to share? When my dad was diagnosed with CML, there were no effective treatments. A few years after his death, some patients were cured with bone marrow transplantation. Now, virtually all patients with CML can experience long-term remission just by taking a pill a day and bone marrow transplantation is rarely needed. Now that’s progress. There is reason to be optimistic. brad kahl, MD 21 21 photo Caption goes here senior leadership category He adli n e go es he re 22 Senior Leadership (left to right): Norman Drinkwater, Daniel Mulkerin, Howard Bailey, Jane Wegenke, George Wilding, Paul Sondel and Patrick Remington The UW Paul P. Carbone Comprehensive Cancer center is wisconsin’s only comprehensive Cancer center. Cancer Center le ade rship and admi n istratio n Senior Leadership George Wilding, MD Director Norman R. Drinkwater, MD Associate Director – Laboratory Programs Howard Bailey, MD Associate Director – Clinical Programs Patrick Remington, MD, MPH Associate Director – Cancer Control Daniel L. Mulkerin, MD Medical Director Jane Wegenke Associate Director – Administration The UW Paul P. Carbone Comprehensive Cancer Center is governed by an Executive Committee. This committee receives input from an External Advisory Committee comprised of academic leaders from across the nation as well as a regional advisory board of community members. Executive Committee Paul Ahlquist, PhD Howard Bailey, MD Søren M. Bentzen, PhD, DSC Paul J. Bertics, PhD George T. Bryan, MD, PhD James F. Cleary, MBBS David L. DeMets, PhD William F. Dove, PhD Norman R. Drinkwater, PhD Meg Gaines, JD, LLM Michael N. Gould, PhD External Advisory Committee Joseph V. Simone, MD (Chair) Simone Consulting Allan Conney, PhD Rutgers University Susan J. Curry, PhD University of Illinois at Chicago Daniel DiMaio, MD, PhD Yale University David Harrington, PhD Dana-Farber Cancer Institute Mark Israel, MD Norris Cotton Cancer Center Peter Jones, PhD USC/Norris Comprehensive Cancer Center Theodore S. Lawrence, MD, PhD University of Michigan H. Kim Lyerly, MD Duke Comprehensive Cancer Center Sanford Markowitz, MD, PhD Case Western Reserve University Frank McCormick, PhD, FRS University of California, San Francisco Cancer Center George K. Michalopoulos, MD University of Pittsburgh Peter S. Rabinovitch, MD, PhD University of Washington Larry Williams, MBA University of Alabama at Birmingham Comprehensive Cancer Center administration Name Paul M. Sondel, MD, PhD Associate Director – Translational Research F. Michael Hoffmann, PhD Patricia J. Keely, PhD Shannon C. Kenney, MD Minesh P. Mehta, MD Hasan Mukhtar, PhD Daniel L. Mulkerin, MD Michael A. Newton, PhD Henry C. Pitot, MD, PhD Patrick L. Remington, MD, MPH Maureen A. Smith, MD, PhD, MPH Paul M. Sondel, MD, PhD Bill M. Sugden, PhD James A. Stewart, MD Jane Wegenke, BS Richard H. Weindruch, PhD George Wilding, MD Advisory Board Members Don & Marilyn Anderson DeEtte Beilfuss-Eager George T. & Sandy Schwartz Bryan Mary Carbone Paul J. Carbone, Co-Chair Diane Craig Chechik Ilene Fielkow June Franklin John Frautschi Meg Gaines Al Goldstein Mary Lou Birkett Goodfriend Forrest Hartmann Hans & Marjorie Helland Sara Hildebrand Patricia Howell Tom & Barbara Kilgore Kevin Koch Nancy Kreilick Phyllis Leach Efrat Livny Charles & Marian Loeffler Paula Lundberg Linda Nielsen Bill Nitzke Louise Rusch Donald Ryan JoAnn Six Plesko William Steinberg, Co-Chair Susan Veatch Mary Wickhem 23 23 The Interdisciplinary Research Complex will be a powerful tool for advancing biomedical research on the UW campus. Discovery In t erdiscipl in ary re s e arch comp l e x research Medical and biological science is continually evolving, and the presence of the next generation of biomedical research is dramatically apparent on the west end of the University of Wisconsin campus. With an impressive footprint and a total of 663,430 square feet at completion, the emerging Interdisciplinary Research Complex (IRC) will be yet another scientific milestone at the university. The facility will be a national showplace, according to Paul M. DeLuca, PhD, Vice Dean of the UW School of Medicine and Public Health and Associate Dean for Research and Graduate Studies, an innovative center designed to remove barriers between basic and clinical research. “Our concept was totally visionary at its inception more than a decade ago,” says DeLuca, “now others are applying the UW’s original vision and creating their own centers.” The IRC’s essential purpose is to inspire creative new ways for scientists to pursue biological research and to apply their ideas directly to problems clinicians face everyday. This model, frequently described as translational research, is a relatively new approach to scientific discovery, and one that wouldn’t have been possible even 10 years earlier. 24 The design of the building is meant to encourage integration and flexibility across disciplines; to facilitate a creative exchange of ideas. Currently under construction are a three-story base housing key facilities such as state-of-the-art animal facilities and innovative imaging technology and an eight-story laboratory tower including two floors for imaging/radiation sciences. This first tower, scheduled to open in early 2008, will be dedicated to cancer research, regenerative medicine, neurogenetics, molecular medicine and neurosciences. The completed complex will eventually include second and third research towers. Siting the building was essential to the vision. It is close to the University of Wisconsin Hospital and Clinics, the soonto-be-opened American Family Children’s Hospital, the School of Medicine and Public Health, the Waisman Center, the UW School of Pharmacy and the William S. Middleton Memorial Veterans Hospital. A growing number of major academic medical centers have been embracing the translational research model. One obvious benefit of translational research, according to the National Institutes of Health, is that basic scientists give clinicians new tools for patient care, and clinical researchers are uniquely able to observe the progress and effects of disease, which often stimulates ideas for additional basic science investigations. Taking advantage of the translational research approach means institutions are focusing more of their resources on teams of faculty researchers who are well trained in inter- and multidisciplinary investigation; scientists who can project the success of laboratory discoveries to patient care and who are excited about designing their explorations around finding very real and human solutions. Institutions are creating environments, such as the IRC, to provide investigators with the tools, the infrastructure and research support necessary to advance multidisciplinary research. These resources not only facilitate moving research breakthroughs to clinical care, they also help recruit and retain promising faculty. Ultimately, the discoveries emerging from facilities such as the IRC will forever change the way medicine is practiced, opening unimagined opportunities to improve human health and well being. innovation 25 25 more than 250 faculty on the UW-Madison campus comprise cancer center membership. Cancer Center me mbe rship The UW Paul P. Carbone Comprehensive Cancer Center brings together the efforts of more than 250 faculty from 55 departments and nine schools on the UW-Madison campus. membership Cancer Center members participate in seven research programs, which optimize intra- and inter-programmatic research and facilitate efforts to apply discoveries to improving the care of cancer patients. To read more about our research programs, please visit www.cancer.wisc.edu. Cancer Cell Biology Program Leader: Paul J. Bertics, PhD Co-Leader: Patricia J. Keely, PhD The Cancer Cell Biology Program seeks to understand the signals that govern the proliferation and invasion of metastatic tumors. Caroline M. Alexander, PhD Richard A. Anderson, PhD Emery H. Bresnick, PhD Richard R. Burgess, PhD William J. Burlingham, PhD Wade A. Bushman, MD, PhD Dongsheng Cai, MD, PhD Nansi Jo Colley, PhD Charles J. Czuprynski, PhD John M. Denu, PhD Sinisa Dovat, MD Jens C. Eickhoff, PhD Frances J. Fogerty, PhD Andreas Friedl, MD Michael K. Fritsch, MD, PhD Daniel S. Greenspan, PhD Jenny E. Gumperz, PhD Majed M. Hamawy, PhD Jacquelyn A. Hank, PhD Colleen E. Hayes, PhD Peiman Hematti, MD Anna Huttenlocher, MD David F. Jarrard, MD 26 Laura L. Kiessling, PhD B. Jack Longley, MD Miroslav Malkovsky, MD, PhD James S. Malter, MD Shigeki Miyamoto, PhD Deane F. Mosher, MD Christopher J. Murphy, DVM, PhD Robert W. Nickells, PhD Sean P. Palecek, PhD Donna M. Paulnock, PhD Donna M. Peters, PhD Arthur S. Polans, PhD Alexander L. Rakhmilevich, MD, PhD Erik A. Ranheim, MD, PhD Alan C. Rapraeger, PhD Jeff Ross, MD Matyas Sandor, PhD Christine M. Seroogy, MD Lewis G. Sheffield, PhD Nader Sheibani, PhD Igor I. Slukvin, MD, PhD Gary A. Splitter, DVM, PhD Xin Sun, PhD M. Suresh, DVM, PhD John P. Svaren, PhD James A. Thomson, VMD, PhD David A. Wassarman, PhD David I. Watkins, PhD Jyoti J. Watters, PhD Jon Pointon Woods, MD, PhD Wei Xu, PhD Cancer Control and Population Science Program Leader: James F. Cleary, MBBS Co-Leader: Maureen A. Smith, MD, PhD, MPH This program aims to reduce the risk, incidence and deaths from cancer as well as enhancing the quality of life for those living with cancer. Henry A. Anderson, MD Sanjay Asthana, MD Timothy B. Baker, PhD Tara M. Breslin, MD Elizabeth S. Burnside, MD Betty A. Chewning, PhD Lisa H. Colbert, PhD, MPH June Dahl, PhD William E. Fahl, PhD Michael C. Fiore, MD, MPH Brion J. Fox, JD Dennis G. Fryback, PhD Ronald E. Gagnon, PhD Aaron M. Gilson, PhD Albert C. Gunther, PhD David H. Gustafson, PhD Lawrence P. Hanrahan, PhD Robert M. Hauser, PhD Robert P. Hawkins, PhD Susan M. Heidrich, PhD, RN Paul R. Hutson, PharmD, RPh David E. Joranson, MSSW Douglas E. Jorenby, PhD Karin T. Kirchhoff, PhD, RN Bruce S. Klein, MD Betty J. Kramer, PhD David M. Kushner, MD Kristine L. Kwekkeboom, PhD, RN Diane R. Lauver, PhD, RN Yu Jim Li, MD Donna O. McCarthy, PhD, RN D. Paul Moberg, PhD Polly A. Newcomb, PhD Patrick L. Remington, MD, MPH JoAnne A. Robbins, PhD Michael L. Rothschild, PhD Tracey A. Schroepfer, PhD Ronald C. Serlin, PhD Stevens S. Smith, PhD Amy Trentham-Dietz, PhD David J. Vanness, PhD Sandra E. Ward, PhD Mark V. Wegner, MD, MPH Whitney P. Witt, PhD, MPH Cancer Genetics Chemoprevention Program Leader: William F. Dove, PhD Program Leader: Howard H. Bailey, MD Co-Leader: Michael A. Newton, PhD Co-Leader: Hasan Mukhtar, PhD The mission of the Cancer Genetics Program is to develop the capabilities of experimental genetic analysis to define causative pathways that affect tumor growth. Judd M. Aiken, PhD Alan D. Attie, PhD Christopher A. Bradfield, PhD Franco Cerrina, PhD Mark W. Craven, PhD Norman R. Drinkwater, PhD Anne E. Griep, PhD James L. Keck, PhD Lorraine F. Meisner, PhD Amy R. Moser, PhD C. David Page, Jr., PhD Richard E. Peterson, PhD Tomas A. Prolla, PhD Carol D. Ryff, PhD Eric P. Sandgren, VMD, PhD David C. Schwartz, PhD Lloyd M. Smith, PhD Michael R. Sussman, PhD Richard H. Weindruch, PhD Brian S. Yandell, PhD The mission of the Etiology and Chemoprevention Program is to determine the causes of cancer and then translate the knowledge to develop and evaluate drugs, vitamins or other agents to try to reduce the risk of or delay the development of cancer. Farrukh Afaq, PhD Nihal Ahmad, PhD Elaine T. Alarid, PhD George T. Bryan, MD, PhD Jason R. Gee, MD Michael N. Gould, PhD Russell F. Jacoby, MD Colin R. Jefcoate, PhD Christina M. Kendziorski, PhD Minakshi Nihal, PhD Michael W. Pariza, PhD Henry C. Pitot, MD, PhD Linda A. Schuler, PhD, VMD Vijay Setaluri, PhD Vladimir S. Spiegelman, MD, PhD Roger A. Sunde, PhD Ajit Kumar Verma, PhD Gary S. Wood, MD Weixiong Zhong, MD, PhD 27 Experimental Therapeutics Program Leader: F. Michael Hoffmann, PhD Co-Leader: James A. Stewart, MD The specific aims of the Experimental Therapeutics Program are to identify novel mechanisms of anticancer therapy and translate them to clinical applications, to perform initial human clinical trials and to move new therapies to disease-specific settings. Nicholas L. Abbott, PhD Daniel M. Albert, MD Mark R. Albertini, MD Hirak S. Basu, PhD David J. Beebe, PhD Helen E. Blackwell, PhD Reginald C. Bruskewitz, MD Natalie S. Callander, MD Herbert Chen, MD Joseph P. Connor, MD Hector F. DeLuca, PhD David L. DeMets, PhD Darin Y. Furgeson, PhD Samuel H. Gellman, PhD James E. Gern, MD Ellen M. Hartenbach, MD 28 Kyle D. Holen, MD C. Richard Hutchinson, PhD Brad S. Kahl, MD Weiyuan John Kao, PhD KyungMann Kim, PhD Jill M. Kolesar, PharmD, RPh, BCPS Ilene D. Kurzman, EdD Glen S. Kwon, PhD Garet P. Lahvis, PhD Glenn Liu, MD David M. Mahvi, MD Gerard J.D. Marriott, PhD Joseph H. Matloub, MD Douglas G. McNeel, MD, PhD Daniel L. Mulkerin, MD Daniel Muller, MD, PhD Terry D. Oberley, MD, PhD Manish S. Patankar, PhD Ronald T. Raines, PhD Scott R. Rajski, PhD H. Ian Robins, MD, PhD Joseph R. Robinson, PhD Arnold E. Ruoho, PhD Ben Shen, PhD Eric V. Shusta, PhD Paul M. Sondel, MD, PhD Santhanam Swaminathan, PhD Jon S. Thorson, PhD Randal S. Tibbetts, PhD Anne M. Traynor, MD David M. Vail, DVM Lynn Van Ummersen, MD George Wilding, MD Jon A. Wolff, MD Human Cancer Virology Program Leader: Paul G. Ahlquist, PhD Co-Leader: Shannon C. Kenney, MD Researchers in the Human Cancer Virology Program study members of families of viruses that cause cancer in people— revealing the mechanisms by which viruses predispose cells to evolve into tumors and by dissecting the routes by which viruses enter cells. Curtis R. Brandt, PhD Teresa Compton, PhD Robert J. Kalejta, PhD Paul F. Lambert, PhD Daniel D. Loeb, PhD Janet E. Mertz, PhD Robert Todd Striker, MD, PhD Bill Sugden, PhD John Yin, PhD Clinical Investigators Participating Across Programs Imaging and Radiation Sciences Program Leader: Minesh P. Mehta, MD Co-Leader: SØren M. Bentzen, PhD, DSC The Imaging and Radiation Sciences Program is focused on improving early detection and staging of cancer as well as developing strategies to improve outcomes of patients treated with radiation. William McChesney Adams III, DVM B. Lynn Allen-Hoffmann, PhD Gabriela G. Cezar, DVM, PhD Suresh R. Chandra, MD Richard J. Chappell, PhD Onofre T. DeJesus, PhD Paul M. DeLuca, Jr., PhD Sean B. Fain, PhD Jason P. Fine, PhD Lisa J. Forrest, VMD Gelsomina Gilbert, PhD Thomas M. Grist, MD Susan C. Hagness, PhD Paul M. Harari, MD Victor M. Haughton, MD Steven P. Howard, MD, PhD Robert Jeraj, PhD Sterling C. Johnson, PhD Frederick Kelcz, MD, PhD John S. Kuo, MD, PhD Fred T. Lee, Jr., MD Leonard A. Levin, MD, PhD T. Rockwell Mackie, PhD Ernest L. Madsen, PhD Mary Elizabeth Meyerand, PhD Charles A. Mistretta, PhD Robert J. Nickles, PhD Bhudatt R. Paliwal, PhD Rakesh R. Patel, MD Walter W. Peppler, PhD Scott B. Perlman, MD Perry J. Pickhardt, MD Mark A. Ritter, MD, PhD Howard A. Rowley, MD Bruce R. Thomadsen, PhD Wolfgang A. Tome, PhD Patrick A. Turski, MD Jamey P. Weichert, PhD Tracey L. Weigel, MD James A. Zagzebski, PhD These faculty members contribute to the clinical research effort by recruiting patients to clinical trials, advocating the benefits of clinical trials to patients, managing the care of patients according to the guidelines of the clinical research protocols and analyzing clinical samples. Ruthanne Chun, DVM Moo K. Chung, PhD Kenneth B. DeSantes, MD Carol A. Diamond, MD John P. Heiner, MD Charles P. Heise, MD Mark B. Juckett, MD Catherine P. Leith, MB, BChir Mary J. Lindstrom, PhD Walter L. Longo, MD Peter A. Mahler, MD, PhD Timothy D. Moon, MD Stephen Y. Nakada, MD T. Michael Nork, MD Diane M. Puccetti, MD Marjorie A. Rosenberg, PhD M. Shahriar Salamat, MD, PhD Aimen F. Shaaban, MD Jude W. Shavlik, PhD Richard A. Steeves, MD, PhD Sharon M. Weber, MD Eliot C. Williams, MD, PhD Robert D. Woodson, MD 29 photo Caption goes here Clinical leadership category He adli n e go es he re 30 Clinical Leadership (Front row – left to right): Vicki Banning, RN, B6/6 Inpatient Nurse Manager; Judy De Muth, RN, MS, Cancer Clinics Manager, Deana Jansa, RN, Bone Marrow Transplant Manager. (Back row – left to right): Teresa Smith, RN, MS, Director – Oncology Services; Stephanie Orzechowski, RN, UW Breast Center Manager; Katrina Lambrecht, Interim Radiation Oncology Manager the cancer center’s focus is on the best care for patients with cancer; on research, education and prevention. Cancer Center compr eh e nsive ca nce r car e At the University of Wisconsin Paul P. Carbone Comprehensive Cancer Center, the goal is to offer excellence in care and service each time patients and family members visit, and to keep improving every day. • Implemented primary nursing model of care on the inpatient oncology, hematology and bone marrow transplant units. • Installed a new Tomotherapy machine in Radiation Oncology. • Implemented the Integrative Oncology Program. Cancer Clinical Services Goals FY 2007 • Implement primary nursing model in all Cancer Clinics. • Implement robotics program in Radiation Oncology. • Continue planning for EPIC implementation in Cancer Clinics in early 2008. • Complete planning for Radiation Oncology expansion with first phase of the project to open in April 2008. Treatment Name Delivering on that promise requires a fervent commitment to quality and to the people, programs, technologies and partnerships that make it happen. To monitor progress, we routinely measure performance and compare it to nationally accepted standards and best practices. We’re proud to be among those setting the standards and creating the best practices that others follow. Cancer Clinical Services Accomplishments FY 2006 • Completed construction and opened UW Cancer Center Johnson Creek in October 2005. • Implemented new technology, Varis Vision in Radiation Oncology—allowing clinic to be filmless—streamlining and accelerating the flow of clinical data. • Improved patient satisfaction in the Cancer Clinics, Radiation Oncology and Breast Center. The Gynecologic Oncology Clinic attained “Star Clinic” status. • Detailed drawings for the Radiation Oncology expansion project were completed. • Chemotherapy Coordinating Council formed with the goal to identify UW standards for chemotherapy. 31 2005 Clinical Trials Statistics SUMMARY OF NEW CANCER CASES 2000-2005, UW HOSPITAL AND CLINICS 750 700 2005 650 2004 600 2003 2002 550 2001 500 2000 450 400 350 300 Number of trials open: Open to adults...................................................237 Open to adults and children.................................27 Open to children..................................................19 Number of trials open: Phase I................................................................55 Small trials that test for overall drug safety, dosage and basic patient responses. Includes Phase I/II and I/III studies Phase II.............................................................122 Trials that look at the efficacy of the treatment and its side effects. Includes Phase II/III studies 250 200 Phase III.............................................................105 Large scale trials that examine the long-term safety and relative success of a new treatment compared to standard therapies 150 100 50 0 Number of patients enrolled in all clinical trials: UWCCC patients..............................................1296 Affiliate patients................................................352 TOTAL.............................................................1648 Head and Neck GI GU Lung NonHodgkins Lymphoma Leukemia GYN Melanoma Female Breast Peds Central Nervous System Non-treatment trials............................................51 31 The UWCCC helps treat nearly half of all cancer patients in Wisconsin, through affiliate partnerships and outreach services. Cancer Center re gion a l part n e rships regional services category Starting in 1989, the University of Wisconsin Paul P. Carbone Comprehensive Cancer Center developed a regional network to advance cancer care and research throughout Wisconsin and northern Illinois. Through these partnerships cancer patients have access to the most sophisticated treatment, clinical trials, patient education material and second opinions. UW Cancer Center, Aspirus Wausau Hospital, Wausau Undertook a joint venture with UW Cancer Center Riverview Hospital in Wisconsin Rapids to offer area patients unique opportunities for coordinated radiation therapy care. Wisconsin UW Cancer Center, Riverview Hospital, Wisconsin Rapids Became the first cancer treatment site in north-central Wisconsin to offer the TomoTherapy HI-ART System of image-guided intensity modulated radiation therapy (IMRT). Also added a new medical oncologist/hematologist, Ron J. Kirschling, MD, FACP, to its medical team. These alliances mean University of Wisconsin physicians bring treatment advances generally only found at academic medical centers to patients in eight regional communities. By working together local and university health care professionals have a tremendous impact on the patients and families they serve. We celebrate their many significant events from 2005 – 2006. Was a major sponsor of the annual Be a Friend 4 Life event, raising awareness about the benefits of early breast cancer screening. UW Cancer Center, Affinity Health System Affinity’s Appleton facility held its first cancer survivor’s day picnic in May for survivors from the communities surrounding both UW Cancer CenterAffinity Health System sites. Wausau Wisconsin Rapids Appleton Oshkosh Manitowoc Introduced Intensity-Modulated Radiation Therapy (IMRT), an advanced form of highprecision radiotherapy that uses computer controlled X-rays to deliver precise radiation doses. UW Cancer Center, Johnson Creek Ended a successful first year with multiple awards recognizing its patient-centered design. The new facility is a partnership among Fort HealthCare, Watertown Area Health Services and UW Health. Madison UWCCC 32 FHN Leonard C. Ferguson Cancer Center, Freeport, IL Received the American Cancer Society’s “President’s Award for Mission Delivery— Education in the Community” for “Plant it Pink—Hope Blooms for Breast Cancer,” an event to increase community awareness of the importance of early detection of breast cancer by selling 25,000 pink tulip bulbs. Johnson Creek Beloit Illinois Freeport Holy Family Memorial, Manitowoc With help from many community supporters created a Heritage Garden to provide a unique setting for patients, family, staff and visitors. Recognized by the Commission on Cancer of the American College of Surgeons for the quality of its comprehensive, multidisciplinary patient care. Beloit Memorial Hospital, Beloit Developed plans in 2006 for infrastructure improvements in 2007, including remodeling their treatment room, upgrading record and verifying software, and providing new office space for their radiation oncologist and dosemitrist. Copy Contributions fi n a ncia l i nformatio n 33 donors listed on the following pages are from july 1, 2005 - June 30, 2006. Cancer Center do n ors an d gifts The University of Wisconsin Paul P. Carbone Comprehensive Cancer Center would like to thank all donors who help our organization maintain its leading role in innovative research initiatives, compassionate cancer care and education for the public and health care professionals. Donors listed on the following pages are from July 1, 2005 - June 30, 2006. $100,000 & Above Donors Donors and Gifts Anonymous Frieda S. Cohn Estate Roger DeMeritt Marie Flanagan Leyer Estate Midwest Athletes Against Childhood Cancer Irene Newman Prostate Cancer Foundation University of Wisconsin Medical Foundation $10,000 - $99,999 Donors Amgen Foundation C. Berwyn & Paula Anderson, Jr. Donald & Marilyn Anderson Adlynn Balfanz Paul & Amy Carbone Choose Hope, Inc. Cindy Crawford Gretchen & Andrew Dawes Charitable Trust Donna Fox John J. Frautschi Family Foundation Friends of Tim Eagle Gammex, Inc. Golf Fore Wolfe & A Cure Grand Aerie Fraternal Order of Eagles Greater Richland Area Cancer Elimination, Inc. Green Bay Packers Craig Hanson HEADRUSH Hedberg Foundation, Inc. Rebecca Higgins Ruby E. Jonas Estate Audrey Keck Dr. & Mrs. Hugh A. Kennedy Foundation Bernard & Sally Killoran LaVaier Kliefoth Estate Nora S. Korwitz Estate Joan Kuypers Steven C. Leuthold Family Foundation James Meyer 34 Matthew & Heather Morris Charles & Carolyn Mowbray Our Hope of Burlington, Inc. Pfizer Foundation, Inc. Roger F. Plantico Estate Jeffrey & Peggy Post Phil Reader Round of Hope Golf Outing Donald & Diana Ryan Jim Ryu & Helen Lho Russell & Carol Schuler Diane Schure Estate State of Wisconsin Department of Justice Paul & Judith Thomsen Tomorrow’s Hope, Inc. UW Hospital & Clinics Authority Wendy Will Case Foundation J. Martin Wolman $1,000 - $9,999 Donors Daniel & Eleanor Albert James & Kathryn Allen Alliant Energy Foundation Susan Allison Altura Credit Union American Association for Cancer Research American Midwest Equipment Company Arnold & Sally Anderson Anonymous Aring Equipment Co., Inc. Melissa Arnold Memorial ASCO Paul Aspinwall Badger Jim Beam Club Robert Bain Robert W. Baird & Co. Foundation, Inc. Robert Barranco Eileen Bauman Allan & Paulette Beerkircher Joel & Kathy Belaire Thomas & Marlene Benzmiller Robert & Donna Betzig Michael & Bonnie Bogen Douglas Brown Richard & Beverly Brown Robert & Susan Brown George & Patricia Bryan, Jr. Frank & Bonnie Burgess Thomas & Barbara Callahan Cancer Sucks Golf Outing Alan Caplan Memorial Fund Marian Caracciolo Mary Carbone Paul P. Carbone MD Memorial Foundation Lloyd Carlson Al Carruthers & Colleen Adams Circle of Hope Bracelets Marvin & Mildred Conney Gordon & Sigrid Connor Co-op Network Cornerstone Advisors, Inc. Credit Union Executives Society (CUES) Creditor Resources, Inc. John Cullen CUNA Mutual Insurance Group Custom Main Services of Madison, Inc. The Cutting Edge Patrick & Kathryn Daly Peter Davis Roland & Mary Jane Day DLA Piper Rudnick Gray Cary US LLP William & JoAnne Doppstadt Roger Duhl Gordon & Ruth Dunn Stephen & Melanie Dvorak John Dweck Charles Eis Lisa Elkin John & Gloria Etter Sharon Evensen George Fait Gordon & Judith Faulkner Fred Fenster Russell & Janet Ferris V. Kirt & Dixie Fiegel First South Credit Union F.J. Turner High School Boys Basketball Team Robert & Angela Flannery Wesley & Ankie Foell Forum Credit Union Joseph Gajdos Barbara Gambino C. Daniel & Margaret Geisler Genentech Incorporated General Beverage Sales Co. William & Julie Gladbach Albert Goldstein & Phyllis Lefcowitz Grand Chapter Order of the Eastern Star of WI Grand Hyatt Las Vegas Mary Granger Judith Green Michael Gregor Olga Grkavac Glenice Halfman Sue & Eugene Hanmer Memorial Golf Outing Edward & Nancy Hanson Lewis & Lorraine Hanson Haraldson Brothers Open Robert & Mona Harty Mary Ann Henning Memorial Fund Nelson & Vera Hicks Charitable Foundation Brian Howell Lung Cancer Golf Outing Daniel & Patricia Huber Philip L. Hunkel Memorial Research Fund Insite Selection Services, International Matilda Joseph Estate Fred Johnson Kent & Sandra Joranlien Kim & Margo Kalepp Brian & Mary Kaye M. Patricia Keller John Kelly Terence & Mary Kelly Kikkoman Foods Foundation, Inc. Thomas & Barbara Kilgore Lois Kilmer Markus Klebermass Dorothy Klink James & Dolores Kohn Howard & Avis Kolpin Fund Michael Kosmak Memorial Charles & Patricia Koval Donald & JoAnne Krause William & Christine Krugler Kris & Penelope Kubly Vicki Lord Larson Judi Lepofsky Gary & Beth Leverton Earl Levitt Irving Levy Liberty Mutual – Dovers Accounts Payable Lenore Lum Lung Cancer Memorial Golf Outing M.G.R. Foundation Madison Curl for Cancer Bonspiel Marshall & Isley Corporation Eugene Mayernick Nellie McCannon Robert & Emily McKay Benstan Meils Deloris Meiners Richard & Pat Moll Agnes Moore Cynthia Morgan Daniel & Victoria Mulkerin Multi-Media Productions USA, Inc. National Credit Union Foundation, Inc. Frederick Nelson Joseph & Stephanie Nichols North Bristol Sportsman Club North Island Credit Union Dennis & Lori O’Donnell Robert & Lois Olson Sue Oppenheim Trust Nancy Orbison Parts Now! LLC Jeffrey Peck & Lisa Resek Peck Janice Pennau Revocable Trust Pepsi-Co Foundation Charles & Barbara Perkins Jane Perlman Robert Pettibone Richard & Sandra Pfahler Daryl Pieper Kenneth & Janet Pike Dan Pohlman Poynette Curling Club Provident Credit Union Charles & Patricia Quentel, III Susan Batt Racine The RCZ Revocable Trust Loeta Reed-Cress Herbert Reif G. Robert & Marjorie Remiker Donna Resek Elliott Resneck Gordon Rice Ronda Richards Richard & Mary Kay Ring Roche Laboratories Richard & Nancy Roloff Wanda Rood Mary Ann Rosar Royal Oaks Elementary School Steven & Julie Rucinski Louise Rusch Wendell Sagendorf Gregory & Susan Samuels Albert Schams Schering-Plough Foundation, Inc. George & Joan Schiller Nancy Schoenmann Kay Schoon Judith Schuster Carolyn Schwartz Sedlock & Associates Michael See Jeffrey & Rohy Seltz Shamrock Club Parade Committee Frank & Margaret Siegel Robert Siewert Memorial Fund Smart Motors, Inc. Mark Solverud Spectrum Brands Springs Window Fashions, LP George & Mavis Steil, Sr. Joseph & Jamie Steuer Emily Stoddard Steven Stoddard Mary Kay Strachota Janis Strauss Michael & Mary Jo Stroh Robert & Martha Suter Thaddeus Suter James & Deborah Swanson Lewis & Diane Taynton TD Securities USA, LLC TDS Telecom Corporation John Thomsen Willard Thurlow TomoTherapy, Inc. Trackside Charities Foundation, Inc. Anne Traynor Unity Health Insurance The University Book Store Margaret Van Alstyne Edwin & Susan Van Boxtel J. Paul & Lois Van Nevel Denis & Laura Vogel Walter Vollrath, Jr. Mary Jane Voss Florence A. Walsh Fund John & Jacalyn Warczak Andrew & Judy Waterman Tracey Weigel Frances Weinstein Cheryl Weston John & Joyce Weston Nancy Wild Memorial David Wilkinson Windsor Garden Walk Wings Over Wisconsin, Inc. Wisconsin Dells Area United Fund, Inc. JoAnn Wollersheim Workers Credit Union James & Jacqueline Wrycha Gail Wurtzler Xeric Federal Credit Union Sol Zaichick Erwin & Joan Zuehlke $500 - $999 Donors Ronald & Sonja Ahlert Lester & Joanne Ahrens Arthur Arveson Peter Bales John & Bernadette Beam Bob & Cathie Beckwith Niles & Linda Berman Wendy Bicknell Robert & G. Kathryn Bray Donald Brieger Bristol Myers-Squibb Thomas & Elizabeth Butterbrodt Cedar Grove Area United Fund William & Jean Cencic Chicago White Metal Casting, Inc. Donald & Wanda Chisholm Leonard Cordaro Dane County Title Company, Inc Decision Strategies International Pictured above is the family of Sam Mobile. The Sammy Cup Golf Outing is held annually in memory of Sam in Sycamore, Illinois. The UWCCC received $4,600 for lymphoma research from the event. Russell & Susan Doty Harold Drecktrah John Duncanson Eagle School of Madison, Inc Laurence & Judith Eiseman, Jr. Diane Elson Donald & Susan Emerich William & Gail Engler, Jr. Neil Epstein & Arlene Margolis Fairwinds Credit Union Bernice Faltersack John Fatura Gary & Mary Feldt Robert Fey Gerald & Penny Fink First Business Trust & Investment Services Emil & Gail Fischer Charitable Gift Fund Marshall & Lisa Flax George & Jennifer Forbeck Four Leaf Lawn Care, Inc. Kurt & Margaret Frehner Doris Gerndt Lawrence & Jean Gohlke Irwin Goodman & Robert Goodman John Gould, III Mr. & Mrs. Bernard Grommes Forrest Hartmann Susan Haviland Donna Hellenbrand Judy Hepp Keith Hernke Michael Higgins Hilldale Land Company, LLC Charles Hobbs Memorial William & Mary Holewinski Harold Holt Homer Howard Charles & Julia Howell Jay & Patricia Iams Brice & Julie Jackson Ardys Janke John Jardine Scholarship Fund JFK Design Build, Inc. William & Linda Johnson Dawn Jorgensen-Heiser Joseph & Barbara Kachelski Barbara Karlen Wendy Kayser Howard & Mary Kidd Gerald & Vicki Klump Sharon Knoop Nancy Kreilick Robert & Candace La Macchia Paul Lambert Gayle Langer Nancy Layng Phillip & Arlene Lee Leeds Charity Fund Mark & Marian Lefebvre Richard & Joan Leffler Marvin Levy Christopher & Melissa Livingston Charles & Marian Loeffler Jay & Janet Loewi Willis Long Lawrence & Lee Ann Lord Paul & Tracy Luber Thomas & Irene Lynch Joanne Maass Madison Curling Club Kristine Mattson MECU of Baltimore, Inc. Margaret Metcalfe Helen Morrell Kurt & Annette Mueller 35 Shown are participants from the 2006 Wisconsin Dual Sports Spring Charity Ride held in Wabeno. This two-day ride, throughout the Nicolet National Forest, raised $7,900 for cancer research. $500 - $999 Donors Bernice Muth Michael Neill Stephen Nelson Nevada CUES Council John Niebler Norbel Credit Union James Norman Stan O’Keefe Patrick & Amaria O’Leary Oregon Washington CUES Patrick Cudahy Incorporated Christopher & Virginia Pedersen Edward & Judy Peirick Merle & Barbara Perkins John Peterson Robert Placek James Potter & Jean Porter Robert & Patricia Porter Quad/Graphics, Inc. Bruce Ravid Maurice & Arlene Reese Grace Fleming Reinhold Trust James & Dawn Reininger Mark & Karla Ritter James & JoAnne Robarts Eileen Roesler Steven Rough & Jody Schwerdtfeger Rough Pauline Rusch Adam Ryan Ronald & Mary Lee Ryan Suzanne Barnes Ryden Raymond Scheid Memorial Peter & Colleen Schmitz Paul Schoemaker Arthur Shannon Gwendolyn Sharratt Frank & Helen Shishilla Alice Slopa SOFCU Community Credit Union Philip & Mary Jane Southworth Jay & Lou Ann Spaanem Eloise Sparger Suros Surgical Systems, Inc. Target Specialty Products Benton & Mary Taylor Tectura Television Wisconsin, Inc. WISC-TV 3 Orville & Ruth Thiel 36 Georgie Toms Memorial Kenneth Townsend Sarita Trewartha Jerry & Denise Tribbey James Twesme Rich Van Duzer & Terri Gorsett Gerritt Van Wagenen David Vergeront Martha Vestling Stuart Vonderloh Richard Vowles Ruth Wagner Robert & Elaine Waldo Donna Weis Penelope Williams Nan Wilson Wisconsin CUES Council WI Region of the Model A Restorers Club. Inc. Winneconne Schools WIPFLi Marilyn Wolf Kenneth Wood J. Patrick Wright Gary Young & Linda Roberson John Zimdars, Jr. Muriel Zwickey $100 - $499 Donors Creed Abell Seymour & Shirley Abrahamson ACE Precision Castings, Inc. ACE Sauk Prairie Phyllis Aceto Robert & Beverly Acker William Ackermann Leroy Adamski ADS Mechanical LLC Advanced Building Corporation Aerial Properties, LLC Jay & Sarah Affeldt Thomas & Carolyn Agard J.F. Ahern Company Margaret Ahlgren Alabama Council of CUES Arnold Alanen & Lynn Bjorkman John & Ann Albert Patricia Alea Peggy Alf All State Lines, Inc. Anita Allison Thomas & Carla Altepeter Charles Amato Joey Amberg Ameren Services American Family Mutual Insurance Company American First Credit Union Amtelco Carol Anchor Josef & Karla Anderegg Bradley Anderson Edith Anderson Howard Anderson Louis & Marguerite Anderson Nancy Anderson Paul & Mildred Anderson Matt & Rita Andis Frank & Helen Andrekus John & Faye Andrews Andrews Federal Credit Union Tracey Anton Mona Antonelli Michael & Rima Apple ARC Milwaukee, Inc. Thomas Archdeacon & Marilyn Lavin Charles & Patricia Armour Perry Armstrong Jr. Cathleen Arnold Mary Arnold Mary Beth Arnold Roland Arteaga Association Forum of Chicagoland Robert & Janyce Aura David & Margaret Austin Jonathan & Susan Axelrod Mary Ayton Carl & JoAnn Bachhuber Russell & Marjorie Bachman Richard & Nicole Backhaus Badger Inventory Service, Inc. Badger Ridge Middle School 7th Grade Class Erik & Elizabeth Bade Tom & Doreen Badtke Duane & Beth Baer Dennis & Naomi Bahcall Joel & Leigh Bahr Curt & Carla Baier James & Mary Baliker Bank-Fund Staff Federal Credit Union Sylvia Banville Diane Barnidge Barron Community Fund, Inc. Richard Barry Robert & Barbara Bartholomew David & Inez Baskerville Thomas & Sally Basting Hirak & Aparajita Basu R. Alan Bates & Jessica Southworth Bates Bernadine Bauer G. Brian Bauer & Rebecca Bull Kurt & Anne Bauer Michael & Colleen Baughn Bruce Bauman Daniel & Karen Baumann David & Diane Bautsch Frieda Baxter Barbara Beale Henry & Lorraine Beaster Barbara Beck John Beck Robert Beck H. William Becker Mary Becker Mildred Becker Ryan Behling William Behling Joan Behr Calvin & Joy Beisswanger Dennis & K. Regina Bell Craig & Christie Bender Thomas & Lynne Bendt Bennett & Bennett CPA’s, PA David & Cynthia Beno Douglas Berge Bruce & Tracy Bergum Martin Berk Leonard & Norma Berkowitz Morton & Barbara Berkowitz Robert Bernardoni & Charlotte Doherty Stephen & Anne Bernsten, Jr. Barbara Besadny Jacques Besant & Patti McGinnis-Besant Bethpage Federal Credit Union Persis Betts Beverly Beutel Marie Bewick Ruth Ann Beyers BFG Federal Credit Union Sean & Stacy Bidinger Robert & Ann Bielefeldt Lawrence & Rita Bierman Brian Bishop Larry & Ruth Bishop William & Kathleen Blair Thomas & Paula Blankenheim Jacqueline Blatchley Sandra Blauert Kermit Bliss Beverly Block Kerry Block Blue Flame Credit Union Andre & Anna Blum BMI FCU Doris Bock Catherine Bock-Weiss Roland & Mary Boeding J. Richard Boelk Michael & Mary Bohn Lester & Diane Boles John & Marian Bolz Robert & Anne Bolz Boncosky Oil Company John & Theresa Boncyk Steve & Nancy Books Harold Borenstein Donald & Helen Botsford Andrew Bowden William Bowen Teresa Bowers Quentin & Inez Boyken Richard & Connie Brachman, II The Brand Research Company Carole Brandt Chuck & Linda Brei Lyle & Carolyn Bremmer Brennan, Steil, Basting & MacDougall, S.C. Laura Brenner Stephen & Mary Brenton James & Jacqueline Bretl F. Anthony & Susan Brewster Jerry & Carole Briesath Harland Bright Wesley & Sonja Brill William & Joan Brock Phillip & Marilyn Brockish Robert Brockman Janet Brodhead Bruce Brooks Susanne Broome Ronald Brovelli Cameron & Sybil Brown Carlton & Helen Brown David Brown Sara Brown John Bruce & Maureen Hall Walter & Ellen Bruce Christopher & Beth Bruns Richard & Mildred Brus Dennis & Barbara Brush Randy & Linda Bryden Frances Bubolz William & Signe Buchholz John & Jackie Buddle Lori Bue Hariette Bugbee Daniel & Kathleen Bullis Jeannine Bultman G. Wayne & Sandy Bunker Lillian Burdick Luella Burgess Derick & Kim Burgher Jonathan Burke Kenneth Burns Robert & Katherine Burris James Burt Sr. Edward & Lois Busby Robert Bush Robert & Carol Bush Marvin & Susan Busta Samuel & Debra Butler Larry & Sheryl Butson Rodney & Susan Byers William & Joan Byram Martin & Lorraine Cadwallader H. Kenneth & Janet Cain Trust Jeffrey Calder California Credit Union League Marsha Callahan Kent & Lynn Calloway Roy Campana & Kerry O’Donnell Capital Brewery Company, Inc. Miles & Barbara Capron Gerald Cardo Jeffrey & Jane Carlson Joseph Carlson & Margaret Nides William & Louise Carr Amy Carroll Bruce & Kristin Carroll Edythe Carroll-Clarke Virginia Cashbaugh Andrew & Susan Cassady Arthur & Beverly Castro Dale Cattanach Cedar Creek Settlement Merchants Assoc., Inc. Center for Advanced Studies in Business, Inc. Central Credit Union of Michigan William Cerny, Sr. Kenneth & Gudrun Chadwick George & Agathe Charbonneau Diane Craig Chechik Oakley & Christine Cheney, III The Cherry Corporation Ramon & Janet Chesner Larry Chiang Teresa Chiaverotti R.J. Chmielewski Lyle Christenson Raymond & Memee Chun Gilbert & Helen Churchill, Jr. Dan & Sue Cira N. Michael & Lenore Cira Citadel Citizens First Credit Union Roger & J. Loretta Clark Mr. & Mrs. James Cleasby Jeanne Cleland Thomas & Phyllis Cline, Jr. James Clum Coast Hills Credit Union John & Lois Coleman Aldona Collani Robert & Patricia Collins Robert Colvin Francis & Barbara Comella Community America Credit Union Community Educators Credit Union Community One Federal Credit Union Daniel & Rita Congdon John & Linda Conkright Harry Conlon, Jr. Richard & Carolyn Connelly Jeffrey & Deborah Conner James & Zoe Connor Conrad’s – Sentry, Inc. Brian & Suzan Cook Meg Cook Robert & Bernice Cook, Jr. John Copp Mark & Kristine Corey Harold & Dawn Corless Charles & Blanche Cornwell Kathleen Corrigan Patricia Cosgrove Maribeth Cousin L. Douglas & Carol Cowgill Jack & Darlene Coyle Daniel & Patrice Coyne Rick & Karen Craig Calvin & Patricia Cramer Paula Craft William & Judith Craig Crane Reed Properties, LLC Tyrone & Therese Cratic Mark Craven & Susan Goral Credit Union Executives Council – Illinois Credit Union of New Jersey Credit Union ONE James & Karel Cripe Gerald & Phyllis Crohn Mary Cromey CUES Illinois CUES Michigan Council CUES Southern California – Arizona Mark & Carol Cullen Ralph Cullen Timothy Cullen CUNA Credit Union CUNA, Inc. CUNA Mutual Insurance Group Executive Benefits Dept. Robert & Mary Cunningham Susan Cunningham Thomas & Colette Curran Robert & Jean Curtin James & Terri Curtis Thomas Curtis Ruth Curtiss Custom Alloy Light Metals, Inc. Elsie Czehno Alessandro & Renee D’Agaro Frank & Patricia D’Angelo Lynette D’Mello Herbert & Brenda Dahlman Dan & Jean Dahm William & Lynn Dailey F.C. & Joan Daniels Michaela Daniels Edward Danz, Jr. Joseph Darcey Robert & Donna Darling Edmund & Susan Dashcund Margaret Daubenspeck Paul Davenport Richard & Rose Mary Davis George & Carol Dawes Helen De Groot David & Kathryn De Mets Richard & Mari De Moya James & Judy De Muth Alfred & Bernice De Simone Charles & Nancy Deadman William DeCarlo & Lorilyn Chamberlin Christopher & Catherine Decker Thomas & Deborah Degnan Violet Dehring Mark & Marchia Delforge Deluxe Corporation Foundation Kay DeMinter Steven & Veronica Dengel Steven Denninger Jane Dennis Richard & Nancy DeRauf Design Concepts, Inc. Herbert & Mary Desnoyers John & Susan Dickens Ronald & Audrey Dierks Donald Dierschke Dale & Alice Doering Ann Doherty David & Nora Dohler Joseph & Joan Dolan Richard Dolan Dennis & Katherine Dorn Peter & Mary Dottl The Douglas Stewart Company, Inc. Michael & Janet Dow Steven & Kristie Dowden Patrick Downing Ron Downing Sean & Jacqueline Doyle Doylestown Charities Fund John & Josephine Draeger Donald & Carole Draheim Gordon & Maureen Drake Alice Draves Joseph & Laura Dresen James & Jane Drill W. Scott & Nanette Dryburgh, III Peter & Barbara Duffy Paula Dulin-Brinson John & Jean Dunlop Richard Duran, Jr. Loyal & Bernice Durand Stanley DuRose, Jr. Dutch Point Credit Union, Inc. Duval Federal Credit Union Kenneth & Janelle Dvorak Gary & Cindi Dyke Leonard Eager & DeEtte Beilfuss-Eager Kathleen Easland Virgil & Betty Eaton Gregory Eckert Warren Eckstein & Barbara Luedtke-Eckstein Jim Edlebeck & Ann Hintz James & Suzanne Effland Paul & Sonia Egbert James & Sharon Egger Hyam & Sheila Eglash Bruce & Rosemary Ehr James Ehrle Ray Eiben & Marilyn Myers Marc Eisen & Connie Kinsella Eisenberg Law Offices, S.C. James & Jan Eisner Jane Eisner Henry & Laurel Ellingson Beata Elliott Charles & Mary Elliott William Elman John Elmburg Dennis Elmer David Ende & Kathleen Murphy-Ende Daniel & Rita Endres Terry Kahlert Eng James & Nancy Engelhart David & Zeena Engelke Leon Epstein Paula Erato-Daggett Frances Erickson Phyllis Erickson Estes Incorporated Scott & Susan Ethun Mark Etzel & Regina Murphy Eustice, Laffey, Sebrenek & Auby Golf Team Betty Evans Leacle & Dorothy Evans D.W. & Lila Evenson David Ewanowski Paul & Monica Fahrni Thomas & Eleanor Fairchild Joel & Rhonda Fait Audrey Falk Richard & Tina Faria Jeffrey & Terri Farley The Farmers State Bank of Waupaca 37 $100 - $499 Donors The Farres-Harrison Family Stuart Feen & Carol Sonnenschein William & Colleen Feist Sidney & Betty Felder Beverly Feltz Douglas Feltz & Wai-Ming Lai Richard & Michelle Feltz Stewart Feltz John Fenton Edith Ferre Charles & Nancy Fetter, Jr. Kristin Ficks Patricia Fiedler Ronald & Joanne Fiedler Diane Field Nancy Fielder Charles Filson Financial Center Credit Union Financial Kinetics Corp. Kendall & Shirley Finger Marvin & Roberta Fink Patrick & Marilyn Finn Daniel & Carol Finnane Michael & Susan Finnane Dorothy Finstad Erik & Tabatha Finstad Clarence Firari First National Bank – Waupaca William & Elizabeth Fitzsimmons Janice Flannery Randy Flannery Wendy Fleer Fleet Wholesale Supply Co., Inc. Fleetwind International Allen & Mary Jo Fleming Lester & Janet Floeter Joel Flottum Florida Central Credit Union Kaj & Karen Foget John & Karolyn Foley Robert & Alvia Forsberg Fort Knox Federal Credit Union John Foster David Foulkes Fox Cities Workforce Development - Job Center Fox & Fox, S.C. Michael Fraboni Francis Investment Counsel, LLC Herbert & Sylvia Frank Joyce Frank June Franklin Kathy Frater Joel Fraunfelder Carol Fredrickson Marvin Freedman Jannan Freiburger Freihoefer Family Gift Fund Christopher Freitag & Ellen Kennedy William & Bonita Frels Roger Friede Sr. Edward Fritsch Marilla Fuge J. Stewart & Shane Fuller Mary Fulwiler Janet Fumuso Leola Gabel Chad Gabert & Amy Stella Mary Gage Gall Plumbing, Inc. Edward & Donelda Gallagly Michael & Lisa Ganske 38 Donald Gardner Gary’s Piggly Wiggly, Inc. Ramona Gasser Russell & Bernadine Gasser John & Lisa Gast James & Patricia Gaugert, Sr. Arne & Deloris Gausmann Douglas & Charlene Gehrke Matthew Geiger Grant & Nancy Gelhar Jacqueline Gemple Nicholas & Angela Genett Peter & Susan George Carl & Jane Geraldson Alfred & Lorena Gerbitz John & Geri Gerold James & Yvonne Gern Gregg & Lois Gerstmeyer James & Karen Geschke Carl & Sheila Getto Sandra Ghandehari Nicholas Giammaraco Delores Gibson Edward & Patricia Gibson Mark & Margaret Giese Thomas & Beth Giese Joseph & Anne Gilles James & Kim Gilmore, Jr. Robert Gilpatrick & Nancy Hilton Glen Hills United Fund Roy & Jean Glise Allen & Martha Godding Mary Godfrey Charles & Janice Goerg David & Susan Goldberg Susan Goldberg Debra Goldstein Nerma Gollin Theodore Goodfriend & Mary Lou Birkett Goodfriend Goodwill Industries South Central Wisconsin Edna Gorder Mark & Lorrita Gorman Jack & Harriet Gorski Donald & Yvonne Gottschalk Robert & Katherine Gould William & Virginia Grabel Carl & Nancy Graf Kate Granick Alden & Lucille Grant Dave & Barbara Grant Grant Thornton, LLP Nikiann Gray-Tarantino Greater El Paso Credit Union Greater Madison Convention & Visitor Bureau Greater Warren Community Federal Credit Union Victor & Jeanne Gregor Grey Horse Homesites, LLC Douglas & Mary Griesbach Michael Griffin Griffith Laboratories USA, Inc. John & Pamela Grinter James Grisamore Paul & Dorothy Grogan David Groteluschen & Caitlin Stoltzmann Group Health Credit Union Carrie Guenther Grumman Butkus Associates, LTD. David & Anne Gryczewski Virginia Gschwind Richard Gumz Gunderson Funeral Homes Joyce Gust Frank Guth Robert & Harriet Gysbers H. James & Sons, Inc. James & Concetta Haag David Haase Heidi Haeberli Anthony Haen, Jr. Donald & Dana Hafeman Paul & Colleen Hagen Ramona Hagen Shirley Hahn David & Nancy Halford John Hall Susan Hall Memorial Fund George & Lois Hallam Ruth Halverson Scott & Cathy Hamilton Terry & Alice Hampton Richard & Laurie Handel James Haney Linda Hanin Evelyn Hanisch Philip & Mary Hanratty Carlton & Mary Hansen Wayne & Beverly Hansen Carryn Hanson David Hanson & Linda Bochert Philip & Mary Hanson Carolee Harari Christopher & Teri Haring Charles & Prudence Harker James & Donna Harrington Floyd & Joan Harris, Jr. Turner & Mary Harshaw Ricardo & Elizabeth Haskins Henry & Virginia Hart John Hart, Jr. Karl Harter & Christina Sheehan Kim & Ann Harter Christopher Harvath Philip & Barbara Harvey Nancy Haselhorst Colleen Hasler Hausmann-Johnson Insurance, Inc. Hawaiian Tel Credit Union Thomas & Diane Haye Heads Up Family Hair Care Heartland Credit Union Veronica Hearty John & Karen Hebbring H. Edward & Kristine Heckman David Heim Insurance Agency David & Charlene Hein Eugene & Veryl Hein Raymond & Barbara Heldt Hans & Marjorie Helland Hanes & Pat Heller Marsha Heller Sandra Helton Philip & Suzanne Henderson Philip & Elizabeth Hendrickson James & Jane Henkel Robert & Marjorie Henkel Nancy Hennen Richard Hennen Charles & Patricia Henrikson Isabelle Henrickson Jane Henry William & Bevain Henry Robert Henseler Heritage Family Federal Credit Union Robert Herman Howard & Lillian Herriot Mark & Patricia Herrling John Hess Robert & Beverly Hess Mark & Robin Hessefort Jennifer Hicks Jerome & Alice Hill Larry & Mary Hill Hill Electric, Inc. Gregory & Audrey Hinger Stephen & Susan Hird James & Barbara Hodder Richard & Sharon Hodge David & Ann Hoffman Kevin & Lorrie Hoffman Tony Hoffmann Earl & Jean Holdorf Gene Holen Roumaine & Kathy Holland Janet Hollatz Lawrence Holley Gary & Patricia Hollman David & Stephanie Honan Honold Family Trust Harold Hoops, Jr. Gregory & Lynne Hopkins James & Lucille Hornung William & Carolyn Horton William & Susan Hotz C. Vernon Howard Roy & Joanne Howard Patricia Howell Wendy Howell Lisa Hrupka Larry & Mary Hudack Kenneth Hueckstaedt & Joanne Rose-Hueckstaedt James & Leonette Huffer Ralph Huiras Margaret Humleker Erik Humlie John & Melanie Humphrey James & Karen Hunter Hunter Douglas Ernest & Betty Huntley Dean & Erva Hunzicker Thomas & Linda Hupf Paul & Teresa Hutson Lorel Huyett Memorial Patricia Huyett Charles & Joyce Hyde Mary Hyland Ideal Packaging Group, Inc. John Idzikowski & Jane Stoltz Dale & Elinor Ihlenfeldt Iowa Credit Union League Indian Mound Middle School Oliver & Shirley Irgens Marie Irrgang Allen & Kay Iskiwitz Family Fund Alan & Claudine Jaeckel Larry & Deborah Jackson Scott Jackson Robert & Carol Jacobson Julie Jagemann Richard & Louise Jahnke Carl & Sandra Jahns James River Equipment LLC Eugene & Lori Jasper Leonard Jastroch George & Marilyn Jelich Dale & Joan Jennerjohn Robert & Geraldine Jennings William & Jacqueline Jeske Robert A. Jetmundsen Foundation Patty Jewett Johnson Bank – Racine David & Mary Johnson Dawn Johnson Doris Johnson Douglas & Mildred Johnson Edward & Rosie Johnson Gary & Lynn Johnson Jeff & JaneMarie Johnson Joe & Catherine Johnson Kenneth & Marilyn Johnson Martin & Ruth Johnson Millard & Mary Johnson, III Van & Mary Johnson Willard Johnson William & Charlotte Johnson William & Jane Johnson George & Carol Johnston Patricia Johnston Lee & Rosemary Jones Ted Jones & Diane Felsted-Jones Reid & Sue Jorgenson George Josheff Conrad & Susan Jostad David & Jean Juedes William & Cynthia Kaether, Jr. G. Robert & Bonita Kaftan Brad Kahl Kahler Law Offices Michelle Kahl-Parham Barbara Kaiser Alan Kalker & Abigail Cantor Darlene Kallaus Donald & Christine Kalscheu Joe & Rita Kaltenberg Daniel & Mindy Kampen Jonathan Kane John Kaney Merlin & Gerd Kanter Carl & Patricia Karcher, Jr. Joyce Karg Kendall & Sharon Karpf Virginia Karstaedt Ben & Lois Kaster Dean & Cynthia Kaster Faisal & Gerda Kaud Jeannine Kaufman Todd & Lisa Kaull Marcella Kautza Arthur & Maura Keene Frederick Kelcz & Sheryl Popuch Steven & Angeliki Kellner Todd & Tracy Kellner George Kelly John & Lee Kelly Richard & Alice Kelly Mark Kelty & Lisa Moore-Kelty Thomas & Ruth Kent David & Mary Jean Kennedy Martin & Mary Ellen Kennedy Kern Schools Federal Credit Union James & Jeanne Kerr Pamela Kerr Violet Kersting Daniel & Ann Kettler Roland & Shirley Keuler Keys Federal Credit Union Thotsaphone & Chanthila Khampane Julie Kidd Daniel & Nancy Kiernan John Kierstyn Kil-O-Watt Klub Henry Kimberly, Jr. Kimberly-Clark Corporation Kin Ree Drywall Company, Inc. Kinecta Federal Credit Union Barbara King Howard King Trust William & Virginia Kingzett Anthony Kiorpes Jack & Nancy Kirby James & Donna Kirner Robert Kirscht Keith & Catherine Kison Randall & Patricia Kison David & Kathy Kistler Kurt Klapperich & Mary Ann Steiner Jeffrey & Mary Klees Arthur & Georgia Kletti Herbert Kliebard Kenneth & Judith Kliebard Delbert Kliebenstein Mary Klinkner Patrick & Kathleen Klinkner Ferdinand & Barbara Klobucar Kevin & Jennifer Kloehn Catherine Kluever Gregory & Bonnie Knechtges Chester Kniech Bill Knilans Kevin & Leah Knope Knothe & Bruce Architects, LLC Carol Knox Suzanne Koch Fred & Valerie Koehler Mary Koenecke Leonard & Janice Koenig Wayne & Patricia Koessl Herbert H. Kohl Charities, Inc. Marty & Janis Komsa Luvern Kopp Erick & Lucy Korbitz Douglas & Judith Kornemann Donald & Jean Koskinen Dorothy Kovacs Ellen Kowalczyk C.E. & Patricia Kozarek Grace Krajco Margaret Kreblein Jacquelyn Kriewaldt Edward Krinsky Shirley & Stanley Kritzik Philanthropic Fund Neal & Eva Kroll Frank & Christine Kromenaker Dolores Krueger Otto & Johanna Krueger Caroline Kubicki Jerry Kuehn David & Marie Kuemmel Daniel Kuesis Joseph & Miriam Kuhn Anthony Kujawa & Susan Eldred-Kujawa Greg & Marianne Kulka J. Raymond & Felicia Kuna Steven & Deborah Kurkiewicz Isidore Kwaterski Robert La Mar Jon La Paz Ladies Auxiliary of Madison Elks, #410 Susan Laemmrich Bradley & Kathleen Lake James & Shirley Lake Peter & Patricia Lamkins Katherine Lamont Pictured are Missy Livingston and her daughter Molly at the 2006 Jewel of an Evening, an annual event which raises awareness and support for the UW Gynecologic Oncology Program. Missy is creator of “Earrings of Love” jewelry, which was featured in the event’s silent auction. Violet Landsness Jill Lane Richard & Christine Lane Daniel & Bernadette Lang Robert Lang & Lisa Lang-Riegel Hubert & Erika Langecker Karen Langer Stanley Langer Teri Larkee Cynthia Larkin Charles & Janet Larsen Jean Larsen Kathleen Larson Thomas & Arra Lasse Lathrop & Clark Gary & Theresa Lau Lynn & Mary Jane Laufenberg William & Susan Laufenberg Kenneth & Brenda Laughery Christopher & Julie Laurent Robert & Marilyn Laurion Mary-Lynn Lavine Ben & Joan Lawhorn Donald & Mary Layden, Jr. Robert Lazarz Judith Leavitt Misha & Cari Lee Jack & Georgia Leech Kimberly Lehman Tom & Judy Lehman Nina Leib Marie Leithauser Roy Lembcke Frank & Harriet Lenhart Miguel Leon-Benito & Julie Yearling Dorothy Lewis Nanette Lewis Peter & Ann Lewis Robert & Ruth Lezotte Kip & Dianna Libman Michael & Elizabeth Lichtenberger James Lichty & Jacqueline Allen Lichty James & Margaret Liebig Erna Liebzeit Anders Linner & Dorothy Johnson-Linner Hope Linton Daryl & Marcia Lippincott Paul & Joann Lippitt William & Dorothy Little, Jr. Efrat Livny Lucille Locicero Diane Loconte Helen Lodge Mavis Loescher Marilyn Lohman Neil & Lori Lonergan Marc & Charlene Longino Vilja Lorenzsonn Judy Lowell James & Marilyn Luck Gerhard & Sonja Luetschwager Carole Lukens Gary Lukken Rolf & Ann Lulloff J. Robert & Mary Ann Lunda John Lunenschloss James & Christine Lutz Jane Lyons Jason Maas Dennis & Valerie Mack Shirlene Mack Kay Mackesey Rae Madar Madison Gas & Electric Company Madison Motorcycle Club Madison Symphony Orchestra, Inc. Madison Top Company Ernest & Helen Madsen Kevin Magee Robert Maichow Harvey Malofsky William & Katherine Malkasian Michael & Diane Maloney Roderick & Wilma Mann Bruce & Cheryl Manthey Fred & Faye Marcus Howard & Marci Margolis Mark Markel & Lisa Steinkamp William & Elisabeth Marling Peter & Rebecca Marnocha 39 Cancer Center staff and volunteers manned their own water station at the 2006 Mad City Marathon in support of runners Jody Schwerdtfeger Rough and Darren Fortney. Jody ran in memory of her mother and Darren is a cancer survivor himself. Both ran to raise money for the UWCCC. $100 - $499 Donors Kathryn Marotz Marsh & McLennan Companies, Inc. Marshall & Ilsley Bank – Madison Charles & Cynthia Marshall Charles Martin & Kathryn Schubert Frank & Marisa Martire John & Ruth Marty Dennis & Sara Marz Massey Employee Benefit Plans Patricia Mathis Roderick Matthews & Marie Sieker Gerald & Barbara Maxwell Mays Insurance Agency, Inc. John & Joyce McAnelly Edward & Marilyn McArdle Paul & Linda McBride Martha McCann & Theresa Harvath Ellen McCarville Joan McCaughn Timothy McConville & Jan Eymann-McConville Richard & Janice McCormick Marilyn McCubbin John McDermott Barbara McDonald Ronald & Debbie McFall Verda McFarlane Michael & Judith McGinley Patricia McGovern Patrick & Angele McGrady McGrath Associates, Inc. Walter & Helen McGregor James McGuire Margaret McGuire Lisa McIntosh Richard & Jean McKenzie Jennifer McKersie Maxine McKilligin Florence McNett Marlie McRoberts Howard & Nancy Mead Diane Medcalf Karena Meehan Hildegard Mefford Brian Meier & Mekel Wiederholt Meier Lloyd & Frances Meier Larry & Renee Meiller Marvin & Frances Mengeling Philip & Marcia Merrick 40 Janet Mertz John & Joellyn Merz Karl & Jami Merz Gary & Sally Messner Kevin & Tina Metcalfe Irmgard Metz Maxine Meyer Paul & Elise Meyer Leonard & Beverly Meyers Jeffery Michalcyzk Robert & Judith Mickelson Wesley & Berniece Mickelson Wayne & Virginia Micksch Donald Miller Duane & Jane Miller Gary Miller Jerome & Penalee Miller Richard & June Miller Robert & Gertrude Miller Robert & Jill Miller Robert & Nancy Miller William & Iris Miller William & Lorraine Miller Gerard & Lorraine Millette Marilyn Milligan Chad & Donna Milne Greg Milward Gigi Mitchell James & Linda Mitchell James & Rita Mitchell Kevin & Leslie Mitchell Mary Ann Mitchell Robert & Karin Moe Mehrzad & Bonnie Mohammadi Arnold & Aletha Mohlman Jean Mohrhauser Thomas & Nancy Mohs David & Jeann Molliconi Darlene Momberg Monona Community Festival Committee, Inc. Tull Monsees Charles Montgomery Phillip & Ruth Montgomery Darin Moody Alexandra Moore Guy & Judith Moore Lee & Mari Lynn Moritz Michael & Judy Morman John Morris Dottie Moseley MPB Builders, Inc. Eugene & Janet Mueller Brian Mullane Douglas & Shirley Mullen Municipal Credit Union Donald & Joan Murphy M. Patrick Murphy Susan Murphy Tele Murphy Gene & Beatrice Musolf Jon & Patricia Myers Walter & Nancy Naab Andrew Naber & Dorie Miller Steven & Irene Nack Nakoma Golf Club, Inc. National Exchange Bank & Trust Erich & Cheryl Natzke The Neckerman Agency Michael & Rosemary Neider John & Shirley Nelesen Steven Nelesen Randy Nell Richard & Judy Nell Douglas & Lynn Nelson Jess & Darlene Nelson Orville & Selma Nelson Robert Nelson William & Linda Nelson Arthur Nesbitt Thomas & Ruth Nesbitt Lyle & Lois Nestingen William & Nancy Nettleton Craig & Susie Nevins Elizabeth Newell New York Life Insurance Group Charles & Rachel Nichols Harold Nichols John & Lori Nolan Mark Nolen David & Susan Norby Dale & Katherine Nordeen Richard & Barbara Norene James & Harriette Norman Tom Norris North Central Trust Company Northeast Council CUES Northern Illinois Corvette Club Norwood Custom Homes, Inc. Tom & Gail Novacheck Marilyn Novinska William & Susan Nusbaum Armin & Rita Nyffeler The Nygren Living Trust Paul & Beth Ann Nylander James & Monica O’Brien Mary O’Dell Timothy O’Keefe Nina O’Kelley Beatrice Occhietti Paul & Barbara Odland Ohio Credit Union League Ohio Education Credit Union Judd & Tracy Olson Greg & Debra Onken Open Pantry Food Marts of WI Scott & Joleen Opsal Optimist International Foundation Optiz Management Inc. No. 2 Floyd & Sharon Organ Peter & Artie Orlik Jean Orvold Lettie Osborne Thomas & Romana Ostrowski William Ostrowsky Otsego Charity Funds Harold Ottenstein Lois Otto Joseph & Mary Ousley Outokumpa Copper Valleycast, Inc. Gary Overboe Richard & Judy Owens Mark & Louise Packard Elizabeth Paddock Rick Page Thomas & Elaine Pagedas Daniel & Janice Pagel Paul Pagenkopf Norman & Valeria Pakes Thomas Palmtag Harry & Virginia Papcke James & Sandra Pape Milo & Deborah Parker Michael & Janis Parkinson Jack & Cheryl Parrino Tara Passow Dennis & Cathy Pattee Robert & Kathleen Paul Richard & Louanne Pauley Richard & Rachel Paull Ratko & Darlene Pavlovic Ann Peckham Maxine Peckham Karen Pederson Peter Peil Ken & Susan Pelatzke Jonathan Pellegrin Donald Penberthy Alan Penn Pennsylvania Credit Union Association Robert & Judith Penrod Pentagon Federal Credit Union Bruce Perchik & Barbara Nichols-Perchik H.J. Pertzborn Plumbing & Fire Protection Gerald & Carol Petersen William & Diane Petersen JoAnn Peterson Georgia Petrie John & Susan Petterle Phi Beta Cabin Quilter’s Sorority Delores Phillips J. Michael & Patricia Phillips Hans & Susan Pigorsch Dennis & Ariane Pink LuAnn Pink-Kratochwill Richard Pire Arthur & Delores Pitas Cecil & Katheren Pittack Stephen & Lesa Pitts Placon Corporation John & Maryanne Plant Steven & Sue Plater JoAnn Six Plesko Pamela Ploetz Charles Plotz Thomas & Janet Plumb Wilfred & Frances Polzer Lori Polzin Point West Credit Union Arthur & Elizabeth Pope C. Renee Poppe Carl Porter Dennis Porter Mary Poser Nancy Powers Prairieview Feeds, Inc. Phillip & Alison Prange Richard Preissel Priority One Credit Union Steve Proefrock & Terry Gall Alan Propst Charles Pruett Otto & Barbara Puls Richard & Marlene Pump Marvin & Jean Pupeter Barb Quamme J. Douglas & Karen Quick James & Lisa Quick Raymond & Carolyn Quick Tim & Edda Quigley Quivey’s Grove, Inc. William & Natalie Raaths Richard & Laurita Radtke Ryan Radtke & Kathy Gore A. Scott Radwill Robert & Elizabeth Ragan John & Betty Rahm Jeff & Karen Raizen James & Michelle Rameker Charles & Lucille Ramshaw Lawrence & Barbara Rapisarda, Sr. Jean Rappold Harold & Thelma Rasmussen James & Elizabeth Rasmussen Roger & Nancy Rathke Jeannine Raufman Michael Redmond & Irene Temple John & Jean Reeb George & Susan Reed Todd Reed & Carol Humenick Don & Carol Reeder Mary Reese Robert Reese Jim Refsguard Timothy Reilley & Janet Nelson Frederic Reimer Elizabeth Reinartz Keith & Cynthia Reissaus Lois Rens Jennifer Renville Janet Reschke Research Products Corporation Diane Resek Jill Reuss Phillip & Joyce Reuter Margaret Rewald James & Barbara Rewey Ben & Karen Reynolds Diane Rezagholi John & Shari Rice Richard Rice Sara Richards Paul Richert Gerald & Lorraine Richter Stanley & Marla Richter Gordon & Susan Ridley Stewart & Donna Rieckman Gerald & Armella Ring Lee & Susan Riordan Lila Ritchie Peter & Carrie Ritz RML Enterprises, Inc. David & Lynne Roark Anne Roberts Catherine Robertson Joan Robinson Marla Robinson Theodore Robinson-Myers Ellen Roche Rocky Mountain CUES Scott & Georgia Roeming Beatrix Roesler John & Jann Roethe Neal Rogers George & Patience Roggensack Rolland & Margaret Roggensack Eileen Rolph Estate Russell & Patricia Rose Tyler Ross Edwin & Bernice Rossini Richard & Lois Rossmiller Richard & Joann Rost Sonia Sue Rotar Barbara Roth Ingrid Rothe Stephen & Kathleen Rothering Jeffrey Rothstein Jerry & Gloria Rotramel Royal & Muriel Rotter Anne Rough Donald & Linda Rough Roundhouse Marketing & Promotions, Inc. Kathryn Rouse Richard & Doris Rudisill Frederick & Patricia Ruegsegger Gregory & Karen Ruffner Dean Rugotska Patrick & Alvina Runde Robert & Laurel Runte Shirley Ruosch Jack & Betty Ryan Janet Ryan Michael & Judith Ryan Nancy Ryan Alfred Sacha Paul & Alva Sachs R. Thomas & Katherine Saether Larry Saevre Peter Sahagian Barbara Sainsbury Todd Sainsbury Leo & Martha Sakowsky Glenn & Lucille Salter Jose Sanchez & Wendy Harbath Daniel Sapiro & Suzanne LaFleur Shirley Sather James & Barbara Schaefer Wilbur Schaefer Marc & Carol Schatz William & Rolliana Scheckler Janice Schefelker Russell & Chari Schieber Earl & Adeline Schiefelbein Schierl Companies Jean Schilling Robert & Marilyn Schilling Fred Schlater Ernst & Faith Schlieter Donald & Narcisa Schmidt Krista Schmidt Paul & Cecilia Schmidt, Jr. Paul & Jane Schmidt Roger & Jolene Schnabel Glenn & Mary Schnadt Donald & Patricia Schneider Tommye Schneider Dolly Schoenberg Schoep’s Ice Cream Co., Inc. Cynthia Schoepp Jeanne Schoepp James & Shirley Schommer David School School Employees Credit Union Robert & Mary Lynn Schraufnagel James & Nancy Schroeder Loren & Mary Schroeder Lawrence & Georgina Schrock Louis & Elizabeth Schueller James & Jean Schuenke Ronald & Barbara Schuler Timothy & Michelle Schuler Douglas & Ruth Schultz George & Dorothy Schultz Julie Schultz Robert Schulz Winton & Ruth Schumaker Fund Larry & Constance Schuster Steven & Wende Schuster Schwab Fund for Charitable Giving Thomas Schwanz Steven & Doris Schwartz Owen & Nancy Schwerdtfeger Ronald & Adele Schwoegler Allan & Barbara Scidmore Score Chapter, #145 Betty Scott Robert & Lana Scott Seaside Helicopters, Inc. Seattle Metropolitan Credit Union Secureworks, Inc. James & Cynthia See Mary See Barbara Seifriz Roger & Shannon Seip Larry & Sue Seitz Sekelsky Family Fund John & Kristine Selk Bruce & Amy Selkirk Timothy & Lisa Semmann Ng Liang Seng Roger & Margery Senn Jerrald & Donna Sessions Paul & Beth Ann Sever Walter & Nancy Sexton, III Luella Shackelford Diane Shadel Midge Perlman Shafton Philanthropic Fund Doris Shain James & Jean Sharer David Shaw & Janice Becker Jeremy & Ann Shea Robert & Rosemary Shea Gregg & Barbara Shimanski Leonard & Bernadine Shimko Neil & Jacqueline Shively Ray & Carol Shubgert Michael & Maria Shulba Peter & Rella Shulla Marvin & Judith Siegert Steven & Barbara Siehr Michael Siemion Donald & Joyce Sikora Mark & Diane Silverberg Deb Simon Francis & Rosemary Simonis Mary Simonson Carl Sinderbrand & Maryann Sumi Robert & Glenda Singiser Skaalen Sunset Homes, Inc. Ellen Skaar Darold & Jean Skelton Richard Skorupan & Carol McNeill Skorupan Kathleen Skrake Harold & Verna Skrenes Eugene & Kathryn Skroch Barbara Slack Helen Slavens Dorothy Sledge L. Joseph & Marlys Sloup Blake & Sheri Smith Charles & Barbara Smith Clayton & Mary Jane Smith Craig Smith & Merritt Clapp-Smith George & Sara Smith Gordon & Shirley Smith Lanny & Margaret Smith Lori Smith Michael & Debra Smith Norma Smith Robert & Betty Smith William & Elizabeth Smith, Sr. Smith & Gesteland, CPA Charles & Jean Smoots Ann Soderstrom Glenn & Carol Solheim Thomas Solheim Albert & Joyce Solochek Steven Soma Catherine Sommer Paul & Sherie Sondel Shiyu Song Jack & Helen Sorge Ronald & Christine Sorkness Jerry & Jeanan Southwood Walter Southwood & Carleen Wild Harry & Bonnie Spiegelberg Rick Spiel Patricia Sporer Lilah Sprecher Springs Harbor Auto Clinic, Inc. Springvale Charities Fund Spurgeon Vineyards & Winery LLC Ronald & Mary Staben Thomas Stafford Stafford Rosenbaum, LLP Sally Stanek Thomas & Leona Stanek Thomas Stanton The Stark Company Bart Starr Raymond & Ellen Stasieluk Sandra Staves STCU Credit Union Henry & Kathie Steare Joyce Steensrud Robert & Marsha Steffen Charlotte Stein Jane Stein Richard Stein Robert & Beverly Stein Marc & Deanna Steiner Gary & V. Terri Steinhauer Robert & Rochelle Steininger Kristin Stephens Charles & Sharon Stern Hattie Stevens 41 $100 - $499 Donors Stevens Construction Corp. Douglas Stewart & Tamara Harvey Jessica Stewart Marjorie Stewart Walter Stewart & Pamela Hanson-Stewart Margaret Stiles Phil Stoddard Thomas & LaVonne Stodola Gregg Stoffel James & Ellen Stone Muriel Stoneman Gerald & Jacquelyn Stordal Michael & Kendra Story Carmen & Katie Stout Elaine Strassburg Anthony & Shirley Stratil Richard & Susan Straus David & Sandy Street John & Patricia Streur Ida Stricker Gregory & Lea Stroncek Seward & Margaret Stroud Craig Struble Larry & Susan Stuckman Martin & Virginia Stuller Charles & Diane Stumpf James & Sheerin Sturm Patrick & Kathryn Sullivan Sun Prairie Lions Club Suncoast Schools Federal Credit Union Frederick & Mary Sundby Barbara Suran Mary Sutherland Robert Swanson Russell & Ruth Swanson John & Kathy Swenson Kenneth & Irene Sweo Swiss Colony, Inc. Philip & Penelope Symes T.W.A. Clipped Wings International Semand Trsae Tan Ralph & Norma Tandowsky, Jr. Travis & Vicki Tank Harold & Ethel Tarkow Dean & Shirley Taylor Rayla Temin Tennessee Credit Union Dean & Michele Teofilo Robert & Marilyn Teper Fred & Betty Terbilcox Marilyn Terwilliger Jerry & Carol Tessen Anthony & Marlayne Testolin Texas Instruments Foundation Gerald & Priscilla Thain Earl & Alice Thayer Jane Thieleke Thomas & Ruth Thielke J. Leroy & Mary Thilly Barbara Thompson Beth Thompson John Thompson & Karen Butler-Thompson Marion Thompson Marvin & Dolores Thompson Don & Cynthia Thomsen Lester & Sandy Thomsen Dennis & Joan Thomson Gregory & Julie Thorn Jack & Elisabeth Thorpe Thrivent Financial for Lutherans 42 Paul & Renee Thums Kenneth Thygerson Timothy Tierney Matt Tiller & Andrea Engebretson C. John & Barbara Tolch Jill Tolman Jill Tomalin Ray & Marion Tomlinson Victoria Topp Thomas & Beverly Tormey, III Tom & Dianne Totten John Touchett Artha Towell William & Elizabeth Towell Towers Perrin Town of Columbus Charities John & Maria Townsend Stanley & B. Ann Trail Trinity Staffing Group Robert & Norma Trojan Betty Trombetta Walter & Viola Trzeciak Gary & Janet Tupy Jerald & Kendra Tutsch John & Judy Twesme Twin City Die Castings Company Wilna Tygum Leonard Tysver Jon & Susan Udell David & Judy Ulery John & Gail Underwood Uniek United Fund of Marion United Nations Federal Credit Union United San Antonio Community Federal Credit Union Unity Hospice James & Linda Upchurch USA Credit Union Jonathan Uttech UW Health Dept. of Gastroenterology Juri Valdov Margaret Van Boven Harry Van Camp Robert & Loraine Van Eerden Judith Van Kirk Michael & Karen Van Overberghe Ron Van Rossum Peter & Mary Van Sistine Garrett & Laura Van Tassel Norton & Tribba Vande Poele, Jr. Jeane Vanderveer Philip Vangsnes Vantage Credit Union Joseph & Mary Varese Neil & Eileen Vassau Betty Vaughn David & Nancy Veenedaal Donald Venden Venture Investors, LLC Lee Vermeulen Jr. & Jill Kolesar Vermont Federal Credit Union Brian & Mary Vick Steven & Donna Villand Stanley Vinge Albert Vinje Miriam Vinje Virchow, Krause & Company Alan Vogt & Patricia Clark Dorcas Volk Verne & Laverne Vollrath Richard & MaryEllen Von Haden Ronald & Barbara Von Haden Von Stiehl Winery W.W. Grainger, Inc. Joyce Waedow Dane & Susan Wagner J.A. Wagner Construction, Inc. Robert & Edna Wagner Stanley & Mary Wagner Candace Walker Dale & Nancy Walker Donald & Nancy Wallace Wal-Mart Store - Baraboo Florence Walsdorf Gloria Walsh Leo & Carole Walsh Patrick Walsh Ted & Ruby Walton Tom & Kelly Walzer Edward & Marie Wanke Terry & Mary Warfield Peter Waterman Ron & Diana Waterman Kenneth & Beverly Watson Lyle & Carol Watson James & Julie Watt Lester & Karen Watters Waupaca Pallet, Inc. John & Susan Waxler, Jr. Weakie Credit Union Deanna Webb Chris Weber Creighton Weber Robert & Anne Weber Susan Weber William & Karen Weber Weber Marketing Group Robert & Shirley Wegenke Albert Wehde Frederick & Mary Wehmeyer William & Barbara Weidanz Dorothy Weigle Sybil Weinstein Scott & Tina Weis Ruth Weisensel Frank Weiss James & Ann Weiss Robert & Joyce Weiss Philanthropic Fund Steven & Kathleen Weller Wells Fargo Home Mortgage Harvey & Bonita Wendel Darin Wendt Michael & Terry Wermuth Betty Werner John Werner Michael Werthmann Marie Wescott Daniel & Joyce Wessley Jay & Rosemary West West Madison Little League James & Joan Westergard Brett & Megan Westrum Marsha Wetmore Ivan & Joan White White Birch Printing, Inc. Whitmire Micro-Gen Research Labs, Inc. Whyte Hirschboeck Dudek SC Nicole Wieck Douglas & Rebecca Wieczorek Peggy Wiederholt Neil Wienke Andrew & Melinda Wilcox June Wild Wild Rose Lioness Club Wild Rose ‘One Fund’ Drive George & Helen Wilding Thomas & Mary Wilding Arline Wileman Joyce Wilhelms Mark Wilke Allen & Judy Wilkins Gerald & Judith Wille Anna Maria Williams Kirsten Williams Neil Williams & Jane Mendelsohn Ruth Williams William Williamson Mary Wilson Paul & Terri Wilson Jane Wimann John Wink & Jennifer Olk Clark Winn Wisconsin Alumni Assoc. Alumni House Wisconsin Capital Management, LLC Wisconsin Distributors LP Wisconsin Insurance Alliance Wisconsin Reinsurance Corp. Wisconsin Vintners Association Wisconsin Winery Association Jane Wise Steve & Alice Wise Elmer Wisnefsky Frank & Grace Witko Christine Wittenberg Barbara Woessner Lynn Wolf Richard Wolf Ronald & Barbara Wolfe Gary Wollenzien Bruce & Linda Wollpert Joseph & Susan Wolters Peter & Karen Wood Lance & Teresa Woods Woodstream Harold & Charlotte Woolf George & Marjorie Wordingham John & Judith Worm Bill & Edith Wright Harry & Joan Wright Paul & Marilyn Wright William & Mardelle Wuerger Erwin Wunn Michael & Nancy Yaffe Robert & Nancy Yahr H. Edwin Young Mark & Malka Young James & Nancy Youngerman Jane Zekoff Warren & Deborah Zelenak Rose Zerwick Alford & Susan Zick, Jr. Helen Ziegler Mary Ziegler Patricia Ziegler Sylvester & Margie Ziegler Richard Ziemann Harriet Ziemer Daniel & Jill Zifkin H. William Zilisch Frank & Diane Zillner Dorothy Zima David & Jill Zimbal Marian Zimbric Donald & Cynthia Zimmerman Allan & Mary Zins Helen Zippel Alvin & Donna Ziven Hassan Zoroufy Gary & Charlotte Zuerner Wesley & Beverly Zulty Gene & Amy Zumwalt Roger & Carla Zwickey Kathleen Zylka We have made every effort to list all $100 and above gifts received between July 1, 2005 through June 30, 2006. If your gift was inadvertently omitted, or if there is an error on our part, we apologize. If you have any questions, please call (608) 263-1677. In-Kind Contributions Badger Bowl Badger Jim Beam Club Bandung Baymont Inn & Suites Best Buy Company, Inc. Best Western West Towne Mall Pat & Andy Biba Bishops Bay Country Club Blue Marlin Restaurant Blue Moon Bar & Grill BR Diamond Suite Café Continental Capital City Coins & Jewelry Capitol Chophouse Chalmers Jewelers Cherokee Country Club Choose Hope, Inc. Circle of Hope Sheri Cosgrove Dan & Patrice Coyne Crandall’s Carryout & Catering Culvers of Middleton Damon’s Madison East Dairy Queen – University Ave. Diny’s Jewelers Douglas Stewart Company The Fanny Garver Gallery Fitzgerald’s of Middleton Francie’s Casual Café & Lounge Cecil & Sheila Gillingham Glass Nickel Pizza Co. Greenbush Bar Dale Hagen Kari Hankins Harbor Athletic Club Hawks Landing Golf Club Johnny Hellwig Richard & Marcella Herfel Hilton Madison Monona Terrace Husnus Just the Two of Us Kitchen Hearth Anne Klaprat Jason Klein The Klinic Kneaded Relief The Kollege Klub Little Luxuries Pete & Aline Lundstrom Roy & Charline Lundstrom The Madison Concourse Hotel Madison Mallards Madison Monona Terrace Madison Repertory Theatre Madison Top Company Maple Bluff Country Club Marigold Kitchen Pictured above are Winnecone Elementary School staff who, for the past three years, have held a “Denim Day” fundraiser for breast cancer research. Just over $2,000 has been raised in total. Marriott Madison West Maple Bluff Country Club Bag Room Staff Charles Martin & Kathryn Schubert Richard & Jean McKenzie Mediterranean Café Benstan Meils Metcalfe Sentry Foods Michael’s Frozen Custard Mickie’s Dairy Bar Milwaukee Brewers Baseball Club The Milwaukee Bucks Warren Misiewicz MMI Timothy Muldowney & Jacquelyn Hank Noodles & Company Olive Garden Open Circle Healing Arts The Original Pancake House Orpheum Theatre Overture Center for the Arts Panera Bread - Fitchburg Panera Bread - Madison Pat O’Malley’s Jet Room Pizza Hut of Southern Wisconsin, Inc. The Prime Quarter Steak House Quivey’s Grove Rejuvenation Spa Romance Jewelers Ray & Carolyn Schirmer Kirk Schnitker Schwoegler Park Towne Lanes Select Inn Smoky Jon’s #1 BBQ Smoky’s Club Soulful Creations by Susan The Soap Opera Star Cinema State Bar & Grill State Street Brats Ten Pin Alley Wayne & Darlene Turney UW Athletic Department UW Health Center for Integrative Medicine UW Health Marketing & Public Affairs UW Hospital & Clinics UW School of Medicine & Public Health Watches by Wackerle William Thomas Designs WISC TV-3 Wisconsin Cancer Council Wisconsin Women’s Health Foundation In Memory Of Memorial gifts are given in memory of a loved one who is deceased. A minimum gift of $100 has been made in memory of the individuals listed from July 1, 2005 to June 30, 2006. Maureen Adamski Mary Ann Allen Kenneth Allison Shirley Amberg Naomi Ammerman Aaron Anchor Ellie Anderson Jay Anderson Joseph Anderson Terry Anderson Claire Apfelbach Eileen Arnold Melissa Arnold Dale Arneson Nancy Babler Barbara Babler-Vollrath Barbara Bachhuber Jeffrey Badtke Marcus Bagniefski Richard Bailey Sharon Bales Mary Bargren B. Kent Bauman Elizabeth Baxter Phyllis Beck Fred Becker George Becker Cathie Beckwith Bunny Finnegan Behling Merlyn Behr Donald Benn Terri Benzmiller Ruth Berge Patricia Berk Lynn Berman Harold Bewick Tyler Birenbaum Howard Blauert Anna Blum Carole Bochis Grace Boelk Nancy Boelter Larry Boh Jane Bohn Mary Bond Frieda Borenstein Jean Bowers Richard Brachman, Sr. Thomas Brenner Helen Brieger Gloria Bright Janet Brown Mildred Brus Mary Linthicum Bryan Duncan Bryant Robert Bue Connie Bugbee Dale Bultman Nancy Burdick Walter Burkheimer Betty Bush Joan Buss Lew Butler Glenn Butters Thomas Callahan William Campion Alan Caplan Dr. Paul P. Carbone Patricia Cardo Myrna Carlson Sally Carpenter Sandra Carroll Elizabeth Carter Arthur & Sally Cassady Peter Cates Carol Keck Christenson Seymour Clarke Alfred Cleland Charles Cline Cynthia Clum Frieda Cohn Mary Colvin Susan Connell-Magee Judy Copp Barbara Corrigan Gene Craft Marlys Cramer Elvin Crispell Marion Cuccia Joan Cullen Marianne Cullen Thomas Cunningham James Daubenspeck Joan Davenport Susan Davis 43 Members of the statewide VFW Ladies Auxiliary present a $16,560 check to Ashley McGuire of the Cancer Center. This donation represents proceeds from multiple fundraisers held throughout the year. In Memory Of Alfons Dehring Kenneth DeVries Freda Diefenthaler Claryce Dierschke Anthony DiSalvo Carolyn Dodge Jean Dolan Deborah Donaldson Alma Doty Gladys Drake Mary Drecktrah Marla Drieling Jean Duncanson Ralph Dykstra Tim Eagle Loren Eckert Jerry Ehrmeyer Ray Eiben Clifford Erickson Robert Erickson Richard Evans Robert Evensen Frank & Elodee Failla Marjorie Fait Bruce Falk Robert Faltersack Mary Fass Janice Fatura Dorothy Feeley Thora Feist Carol Feltz Valmai Fenster Robert Fettig Marlene Fey Michael Fink Jim Foley M. Sandra Foster Robert Fox William Fox James Frank Martin Freedman James Frehner Eldon Freiburger Don Fugere Stanley Fulwiler Walter Fumuso Joseph Gambino Robert Gard Robert Gasser Gerald Gausmann 44 Marc Gempler Eugenia Gerken Doris Gerndt Reza Ghandehari Stanley Gibson Rose Gladbach William Goldberg Sherry Goldstein David Gorski Judith Gothard Janet Gould Jack Gracey William Granger Wesley Grant Frederick Graves Ruth Green Patricia Griesbach John Grkavac Valentina Grkavac Clifford Gust Peggy Haen Dana Hafeman Jim Haggard David Hague Cletus Hahn William Halfman Susan Hall Helen Halverson Marsha Hamilton Dexter Haney Eugene & Sue Hanmer Alberta Harr Peter Hasler Lenna Hathaway Todd Haukom Robert Havens Melanie Heald Joseph Heim Armond & Eleanor Heimerl Sandra Hein Norman A. Heiser Patricia Helland Vernon Hellenbrand Ellen Jane Henderson G. Robert Henderson Mary Ann Henning Donald Henrickson Betty Henry Jean Henseler Raymond Hepp Eileen Herman LeRoy Heuler Elizabeth Hillhouse Charles Hobbs Anton Holewinski Diane Hollatz Mary Holley Daniel Honold Elizabeth Hopkins Paul Horbinski Louise Hotz Marjorie Howard Brian Howell Cheryl Hoyt Beth Hubbard Mary Huber Peter Humleker, III Lorel Huyett Donald Janke Frantie Jessie Linda Jett Alice Johnson Lila Johnson Linda Aplas Johnson Mary Johnson Willard Johnson Ruby Jonas Michael Jordan Matilda Joseph Martha Josheff Gustave Juhlin, Jr. Dorothy Kahlert Maureen Kalinowski Frederick Karg Kenneth Karlen Erich Kasper Cynthia Kaster Arthur Kautza John Kayser William Keck Rachel Kelcz M.P. & Ivy Kelly Christopher Kettner Brad Kerr Jo Kerr William Ketchum Thomas Kieffer Judith Kierstyn Sally Kind Ronald King Mary Kirkpatrick Leila Kittleson Ann Stroh Klebermass Bernice Kliebard Joyce Kliebenstein LaVaier Kliefoth Kevin Klingbeil Roy Klink Henry Klinkner Larry Kluever Frederic Knilans Donald Knox Robert & Maryalice Koehne Marguerite Kopp Nora Korwitz Jean Koskinen Mike Kosmak LaVerne Kozminski John Kraft Wilfred Krajco Anne Kraus Lucian Krawczyk Kitty Kreft Elmo Kriewaldt Eleanor Krizenesky Karin Kromenaker Mark Krone Henry Kubicki Karen Kuehn Yvonne Kuhn Susan Kuzan Robert Laemmrich Barbara Lakaie Douglas Lamont Robert Langer Ellen Lapinski Carol Larkee James Larson Gerri Lavine Donna Lawhorn Mr. & Mrs. Ira Lecy Ronald Leib David Leichtfuss Rita Lenhart Judi Lepofsky Marie Flanagan Leyrer Merlin Liebzeit Martha Lippitt Joe Locicero Edward LoConte George Loescher Ginger Long Edgar Lorenzsonn Kirt Ludwig Alice Lukken Nathaniel Lynch Gwendolyn Madsen Richard & Marie Malchow Bernice Maggio Blanche Margolis Michael Marinelle Melva Marling John Marotz John Marty Dana Maselter Melvin May Michael McCannon Peter McCarville Barbara McCullough Robert McDermid Esther McFarlane Robert McFarlane Mac McGuire Christine McHugh Alvina McIntyre George McKilligin Max McQuade John Meehan Mary Meeuwsen Larry Meiners V. Thomas Metcalfe Barbara Meyer Eugene Meyer Gary Michaels Arletta Miller Colleen Miller Rosemary Miller James Mitchell Paul Mittelstaedt Sharon Moberg Salvatore Mobile Howard & Rosemary Moebius James Montgomery Matthew Morrell Mary Mucks Lloyd Mueller Robert Mueller Lisa Mullen Marjorie Musolf Shirley Musser Frank Muth Robert Najem Arthur Nelson Carol Nelson Debbie Nettum Kent Newell Jeanette Nichols John Norman Robert Novinska O. Richard Nutter Lois O’Byrne Mary Ellen O’Keefe Colleen O’Meara-Schams Victoria Oakes Anthony Occhietti Elnore Okruhlica Thomas Olk Alice Olson Sue Oppenheim F. Harwood & Lucile Orbison Ernest Osborne Ruth Ottenstein Darwin Otto Donna Overboe Yvonne Ozzello Mary Padgham Floyd Parpart Robin Paschal Charlene Paul Janet Pavlini L. Clark Peckham Bruce Pederson Carolyn Peterson Eleanor Pettibone Ellen Phillips Marla Phillips Judi Pieper Neil Pier Gary Pike Robert Pike Clement Pink Roger Plantico Joseph Plotkin Rose Plotz Thomas Polhman Rose Pruett Roger Quamme John Quick, III Clarence Rabas Dannielle Radtke Albert Ravid Rose Ravid Kathleen Reader Deborah Reese Dana Reeves Patsy Reif Roger Resek Dory Resneck Joyce Reynolds Richard & Dorene Rice Anthony & Mary Richtsmeier Wayne Ritchie Eldon Roesler Mary Rogachuk Eileen Rolph Alex Rose Maurice Rosefelt Joan Rosenberg Elmer Rouse Geraldine Royko Ricky Rudisill James Ruosch Roger Rusch Thomas Ryan June Saevre Constance Sahagian Aurora Samuels G. Irving Schefelker Raymond Scheid Adeline Schiefelbein Herbert Schlater Michael Schmitt Sue Schneck Kenneth Schneider Lee Schoon Merle Schuler George Schultz Gilmore Schultz Robert Schultz Mary Schumacher Jack & Diana Schure Alan Schwartz Nancy Schwerdtfeger Henry Scoles Daniel See Kathleen Semrad Cindy Sexton Darryl Shain Lawrence Shapiro Warren Shrake Elsie Siegel Ethel Siemion Eddie Siersema Robert Siewert Eleanor Silverman Myron Simonson Eugene Skaar Paul Skelley George Sledge Robert Slopa Alan Smith Betty Smith John Smith Mary Ziegler Smith Charles Sommer Karl Southworth Max Sparger Leslie Sprecher Malcolm Stack Francis Stadele Mary Ellen Stafford Robert Stanek Brett Stanley Robert Stare Irvine Stein Lloyd Stein John Stewart Frank Stiles Matt Stivarius Helen Stockland Marcy Stoddard Susan Stoddard John Stoltz Wililam Stoneman Richard Strauss Don Sturtwant Reinold Suchomel Ellagonda Sullivan Steve Sullivan Michelle Suter Dawn Tanner Nick Tarantino Howard Temin Richard Terwilliger Karen Teschan Lorraine Teuke Allen Thieleke Ron Thilleman Florence Thompson Raymond Thompson Constance Thurlow Grover Tillett Georgie Toms Thomas Towell Eva Townsend David Tribbey Keith Tripke Sheila Twesme Irene Van Boxtel Frances Van Nevel Jay VanSloan John Veatch Frances Venti Nelson Vike, Jr. Laurabelle Vinje Rudolph Vokovan Suzanne Voss Erwin Waedow Otto Wagner Dick Wakenight Florence Walsh Richard Walsh Ted Walton Suzy Watson Terry Webb Loretta Weber Thomas Weber Rob Wegenke Conrad Weis Marion Wermuth Jung Werner Fred West Betty Whaley Leo Wiegand Eileen Wild John Wild Nancy Wild Donald Wilke Florene Wilke Lorraine Wilkie Richard Williams Stanley Wilson Paul Wimann Beati Winn Mark Wirtz Jack Wise Darlene Wisnefsky Karl Woessner David Woeste Paul Wolf Eric Wolfe Robert Wollersheim William Wollin Christopher Wood Donna Wood Renate Wunn John Wyatt Susan Yost Donald Zach Erich Ziemann Donald Zima Frank Zuerner Roger Zwickey Thomas Zylka In Honor Of Honor gifts are given in recognition of a loved one who is living. A minimum gift of $100 has been made in honor of the individuals listed from July 1, 2005 to June 30, 2006. Colleen Adams Eva Anderson Abby Armstrong Timothy Bierman Carla Blum Tara Breslin Beverly Brown George Bryan Nancy Burdick Nathan Byram Marlene Cable Torrey Calkins Tom Callahan Andrew Carr Louise Carr Wesley Christianson Roger Clark Scott Clem Corine Cohn John & Marianne Cullen Kathy DiPadova Mr. & Mrs. Tom Drake Sandra Dykstra Kate Emerich Brian Farrell John Fatura Robert Fettig Patricia Fox Jared Fredrickson James Gilmore Mary Grogan Mary Ann Hager Edward & Nancy Hanson Paul & Sarah Harari Chris & Teri Haring Ellen Hartenbach Joseph & Norma Harvath Jane Harvey Shirley Heimerl Sharon Hodge Doug Hoffmann Matthew Hoffman Will Holm Janeille Hornslein Steven Howard Mary Lou Hudack Richard & Louise Jahnke David Jarrard Chris Johnson Ted Jones Sandra Joranlien Mark Juckett Brad Kahl Merlin Kanter Pam Keating Mary Lorene Keller Thomas & Barbara Kilgore Doris Knox Michael Krebs Hana Krembs Johanna Krueger Betty Kuhls Diane Langeteig Glenn Liu Thomas LoConte Walter Longo Richard Love Thomas Lucas Bambi Maloney Lynda Maselter Karen McCannon Richard McCormick Judy Meyer Karen Milner-Adams Aletha Mohlman Henry Mueller Inamm Najem Steven Nelesen Robert Neuendorf Lindsay Nolan North Bristol Sportsman Club Members Katie Paul Gay Pelock Cathy Plate Robert & Gale Radtke Linda Reese Dawn Reinecke Mark Ritter Ian Robins Lindsay Rommelfanger Emanuel Rotter Jody Schwerdtfeger Rough Alvina Runde Connie & Jan Ryan Barbara Schaefer Albert Schams Joan Schiller Judy Schuster Nancy Schwerdtfeger Ethlyn Shadel Judy Siegert Terri Smith Wendell & Kaitlyn Smith James Stewart Jane Straus Michael Sturm Geraldine Torti Diane Vesely Berton Voise Robert Wagner John Wegenke Robert Wegenke Bill Weinert James Weiss Tom & Susan Welch Peggy Wiederholt Carleen Wild George Wilding David Williams & Carol Jefferson Mary Wolf Jody & Sue Wolters Michael & Rowena Young Catherine Zdeblick Steve Zelenski Lucille Zimmerman Andy Zucker Roger Zwickey Pictured are golfers Dave Grant (event organizer), Kim Kalepp, Carleen Wild and Mike Bidwell at the annual Lung Cancer Memorial Golf Outing held in Baraboo. Now in its fourth year, the event has raised just over $32,320 for the Creating Hope lung cancer campaign. 45 for the fiscal year ending june 30, 2006 Cancer Center fi n a ncial in formation Operating Results for the Fiscal Years Ending June 30, 2006, 2005, 2004 and 2003 FISCAL 2006 FISCAL 2005 FISCAL 2004 FISCAL 2003 Core grant from NCI $5,950,249 $5,012,413 $5,081,743 $4,982,378 Other federal awards 97,831,063 93,915,646 74,007,463 57,104,445 Industry and other 15,932,403 17,858,051 12,709,340 7,819,247 119,713,715 116,786,110 91,798,546 69,906,070 5,423,742 4,600,175 3,706,914 2,428,539 853,141 920,271 1,000,820 967,617 46,000 60,830 47,825 148,434 899,141 981,101 1,048,645 1,116,051 1,479,850 1,321,496 955,921 459,530 984,357 739,070 804,204 1,044,284 128,500,805 124,427,952 98,314,230 74,954,474 61,801,409 58,326,534 47,791,234 37,467,901 2,662,573 2,022,249 1,613,682 1,290,836 11,422,570 11,166,212 10,041,091 6,769,779 1,525,488 1,649,753 1,254,724 867,290 Other expenses 21,362,185 18,705,380 13,058,466 10,365,935 Overhead support to UW-Madison 29,945,866 27,857,459 23,479,837 16,976,709 128,720,091 119,727,587 97,239,034 73,738,450 ($219,286) $4,700,365 $1,075,196 $1,216,024 SOURCES OF SUPPORT Grants and awards operating Results Contributions University of Wisconsin School of Medicine and Public Health All other Fees for research support services Investment earnings TOTAL SUPPORT EXPENDITURES Salaries and benefits Equipment Services and supplies Travel TOTAL EXPENDITURES SUPPORT GREATER THAN (LESS THAN) EXPENDITURES During fiscal 2006 total support increased to $128.5 million or an increase of 3.3%. Support from contributions totaled just over $5.4 million or an increase of 18% during the year. Since fiscal 2003 contributions have grown 123%. Total expenditures in fiscal 2006 reached $128.7 million. As in prior years, salaries and benefits represented the largest component of expenditures at 48% of total expenditures. 46 McArdle Lab—9% Expenses by member department During the year ending June 30, 2006, research and training-related expenditures were incurred in more than 40 UW schools and departments. The Cancer Center member departments cover a wide range of disciplines across the UW campus. The two largest departments as measured by expenditures were the Department of Medicine and the McArdle Laboratory for Cancer Research. All Others—20% Medicine—13% School of Pharmacy—4% Population Health Sciences—5% Surgery—3% Ophthalmology—2% Cancer Center Core Grant—5% Pediatrics—4% Chemistry—3% Pathology—8% Pharmacology—5% College of Agricultural & Life Sciences—6% College of Engineering—6% School of Veterinary Medicine—4% Human Oncology—3% UWCCC Member support As of July 1, 2006 Cancer Center member annual external research and training support totaled $140.3 million, a decline of just under 1%. This small decrease reflects the tight federal budget and the trend for longer intervals between funding of NIH grants and automatic budget decreases in funded NIH grants. $150,000,000 ALL OTHERS $120,000,000 NIH NCI $90,000,000 $6,0000,000 $30,000,000 0 FY 2000 FY 2001 FY 2002 FY 2003 FY 2004 FY 2005 FY 2006 Construction Grant—4.99% UWCCC programs This chart presents the level of external support for the Cancer Center’s program areas for the fiscal year starting July 1, 2006. In addition to the program areas, the Cancer Center receives external support for its Core Grant and funding for cancer-research facilities. Cancer Control & Population Science—18.60% (44 members) Core Grant—3.98% Experimental Therapeutics—16.76% (46 members) Human Cancer Virology—4.85% (11 members) Cancer Cell Biology—20.48% (47 members) Etiology & Chemoprevention—6.93% (21 members) Imaging & Radiation Sciences—6.50% (42 members) Cancer Genetics—16.91% (22 members) 47 “We make a living by what we get, but we make a life by what we give.” –winston churchill Contributions A commitme n t to the futur e Your gift to the UW Paul P. Carbone Comprehensive Cancer Center supports greater innovative research initiatives, compassionate cancer care and education for the public and health care professionals. hope Your contribution also enables our researchers to explore new ideas, purchase new technology for effective cancer research, and develop better methods of diagnosing, treating and preventing cancer. Funding for the Cancer Center’s research, outreach and treatment programs is more important than ever. There are many ways to support the UW Carbone Cancer Center (UWCCC): UNRESTRICTED GIFTS are truly valuable because they provide the flexibility needed for research to move quickly in unexpected directions and to swiftly pursue promising clinical applications. Unrestricted gifts also provide resources to cover the costs of critical services not entirely funded by other support. DESIGNATED GIFTS benefit specific programs of your choice. Funds may be designated for initiatives in specific areas of cancer research, patient care and educational needs. CORPORATE MATCHING GIFTS are an excellent way to increase your giving potential to the Center. For more information, please 48 contact your human resources office or our development office, (608) 263-1677. MEMORIAL AND HONOR GIFTS allow contributors to recognize loved ones in a special way. Memorial gifts are made in memory of family members, friends or colleagues who have passed away. Honor gifts show someone in your life a measure of affection, admiration or gratitude. When such gifts are made, a special notification is sent to the family or individual. MAJOR GIFTS are a specific way for individuals, organizations, corporations or foundations to contribute to the University of Wisconsin School of Medicine and Public Health’s HealthStar campaign. Funds from this campaign will help build the Interdisciplinary Research Complex, which will prominently feature the UW Paul P. Carbone Comprehensive Cancer Center and innovative research. Please call (608) 263-1677 for more information. ENDOWMENTS to sustain programmatic development are an option to create a lasting legacy in the benefactor’s name. OTHER EXAMPLES OF GIVING include purchasing research equipment, funding fellowship or research programs, sponsoring special events, or underwriting programs for the community or health care professionals. PLANNED GIVING, in the form of gift annuities, charitable remainder trusts or designating the Center in your will, is also an option. The UW Paul P. Carbone Comprehensive Cancer Center can also be named as a beneficiary of retirement plans, trusts or life insurance policies. The Office of Planned Giving at the University of Wisconsin Foundation can assist in planning these gifts. Please call (608) 263-4545. CONTRIBUTING ONLINE is possible by going to www.uwhealth.org. Choose the “Donate” button and then select one of the Cancer Center funds listed. The University of Wisconsin Foundation is the official fundraising and gift-receiving organization for the Cancer Center. For specific information about these giving options, visit the UW Foundation’s website: www.uwfoundation.wisc.edu FOR MORE INFORMATION about contributing to the UW Paul P. Carbone Comprehensive Cancer Center, please contact: Ann Johnson UW Paul P. Carbone Comprehensive Cancer Center 600 Highland Avenue, K4/658 Madison, WI 53792-6164 (608) 263-1677 [email protected] CREDITS EDITORS Craig Robida UW Paul P. Carbone Comprehensive Cancer Center Linda Dietrich UW Health Marketing & Public Affairs ART DIRECTION AND GRAPHIC DESIGN Christine Klann UW Health Marketing & Public Affairs PHOTOGRAPHY Todd Brown Michael Lemberger Tom McInvaille David Nevala CONTRIBUTORS Rhoda Arzoomanian Andrea Engebretson Gayla Garlick-Hansen Paula Goode Ann Johnson Jan Johnson Mary Makarushka Ashley McGuire Bob Millholland Jerome Rather Lori Saffian Teresa Smith Stephine Wasielewski Jane Wegenke George Wilding SPECIAL THANKS Judy De Muth William Dove David Gustafson F. Michael Hoffmann Brad Kahl Michael Lemberger Rebecca Marnocha Kathy Schell FOR MORE INFORMATION For patient services at the UW Paul P. Carbone Comprehensive Cancer Center, please contact: Cancer Connect (800) 622-8922 or (608) 262-5223 [email protected] For information on the latest research initiatives, news and upcoming events, view the UW Carbone Cancer Center website: www.cancer.wisc.edu CONTRIBUTIONS To contribute to the UW Paul P. Carbone Comprehensive Cancer Center, please contact: Ann Johnson UW Paul P. Carbone Comprehensive Cancer Center 600 Highland Avenue, K4/658 Madison, WI 53792-6164 (608) 263-1677 [email protected] COPYRIGHT © 2007 UW Paul P. Carbone Comprehensive Cancer Center 600 Highland Avenue Madison, WI 53792 (608) 263-8600 www.cancer.wisc.edu NCI CCC UW Health is a patient-focused, three-pronged academic health system supported by: •University of Wisconsin Hospital and Clinics, a 471-bed facility that ranks among the finest hospitals in the United States. •University of Wisconsin School of Medicine and Public Health, the UW-Madison campus home of the faculty members who do research, teach and provide patient care. •University of Wisconsin Medical Foundation, the academic group practice that supports the clinical faculty of the UW School of Medicine and Public Health, including more than 1,000 physicians who practice at 50 locations. CC11895-1106P The University of Wisconsin School of Medicine and Public Health is recognized as an international leader in educating physicians, investigating the causes of disease, finding innovative solutions to medical problems and translating research into compassionate patient care. The UW Paul P. Carbone Comprehensive Cancer Center is one of only 38 comprehensive cancer centers designated by the National Cancer Institute, the lead federal agency for cancer research.