Variation of the Hemoglobin Level with Age and Sex

Variation
W.
By
T
HE
W.
aid
an
therefore
adequate
Altitude
levels
for
the
from
tiot
he
most
of
Canada,
the
to provide
reliable
as
have
a factor
l)eems
the
years
of
United
to
age
States,
justify
particularly
values
before
among
people
same
these
tables
magmsitude
of women
are,
showus
levels
the
United
with
advaisciusg
to obtain
amid after
sufficient
data
on adult
middle
age, amid to itidicate
adults.
Sm’h
information
differemsces
people
States,
of
could
some
other
SUBJECTS
The
From
N.
the
of
Maritime
Ofl
1308
male
between
Regional
AND
and 1424
November
beets
the
last
these
cots-
reported
tens years,
The
values
methods
w’ith
ose
typical
of those
usually
adult
life. The other
geuserally
low’er.
but
women
upon
is little
that
The
sex
it is smaller
the
its
treisd
its reports
or no
a decrease
of
of
the
(‘hausge
its
occurs
in
people
to allow’ comparisoms
of
the degree
of the sex differemsce
be of fairly
s’ide interest
amsd use,
likely
to exist
hetw’een
hemoglobin
in many
other
localities
in Camsada,
coumstries,
particularly
at sea
level.
METHODS
feussale
12,
Laboratory,
have
l)y Wiustrohe,
but
hemoglobin
is kmsowus
subjects
1952,
anstl
National
bet weeu
May
22,
Research
tlue
ages
1953.
The
Council
of
9,
1954.
of 9
Canada,
98
arutl
youngest
subIlali-
S.
Submitted
We
aspect
in order
to extend
informatious
our
6 years
of age upw-ard.
We w’ished
w’ould not be
Halifax
amsd those
amid possibly
The survey
was (lone
years. It was carried out
fax,
age,
here was umidertakems
of individuals
from
significant
among
the
is
be comssurveys
ots this
Britaims.
of
however,
as that
reported
levels
older
because
must
have
Little
amid Great
comparisoms
among
older
people.
A differemsce
hetw’eems
mets and
hemoglobin
values
in late adult
life has been
remarked
last few years.
Evidence
has beets provided
that
there
The work
hemoglobin
used
l)asis
its relatioms
states
decade
withims
mostly
in
the
values
factors.
which
values
the hemoglobin
men.46
is w’idely
affectimsg
domse.1
reported
in this
survey.
values
givems by Wintrohe2
are
of mets amid w’omems throughout
adult
Sex
factual
figures
and with those
Its tables
2 amsd 3 the
coissidered
as characteristic
is of the
blood
of hemoglobims
considered
100
similar
another
for
LEONARD
A sound
of other
geographic
hemoglobims
values
4 to about
sufficiently
difference
G.
whets
borderlimse
omsly about
the last
surveys
importamsce
3 summarize
from
were
and
VERNA
of health.
tremsd
important
Within
amid exteist
where
,
particularly
the
Age
respect
childreus
from
six years
of age upward
amsd young
most
attemstion.
The state
of kmsowledge
con(’ermsiusg
Isemopopulatioms
groups
is, however,
still umssatisfactory.
possible
1 2, and
individuals
AND
state
establishimig
useed
localities
cerising
Tables
of the
is most
surveys.
probably
in
SPECK
with
CONCENTI(ATH)N
in number
have
levels
Level
EIaLY5
assessmetst
Its this
received
in some
hematology.
used
in
and sex. This
as in msutritiots
women
globin
Hemoglobin
HAWKINS,
necessary
to age
sidered,
for
the
HEMOGLI)BIN
as
been
of
must
course
December
thank
of this
Dr.
survey,
9,
E.
1953;
Gordon
and
accepted
Vounug,
for hell)
for
the
publication
Director
ins preparing
999
February
of this
the
nsaterial
Laboratory,
for
for publications.
ativice
dun
rig
1000
VARIATION
TAB
Age
No.
OF
hEMOGLOBIN
I.E
1 -Hemoglobin
of subjects
Hgb
(‘hildren
av.)
Locality
Ref.
13.3-13.6
Great
Britain
19
13.2
Great
Britain
20
1483
12.8
British
5-il
3575
1456
12.8
13.3
Floritia
Saskatchewan
5-15
200
12.5
hamilton,
5-16
518
12.4
East
8-13
515
13.1
Louisiana
Columbia
14
12
15
Ont.
10
Ont.
York,
10
21
7-14
358
13.5
Michigans
7-14
1669
13.6
Saskatoons,
S
Sask.
9
297
h)oys
13. 1-13.8
Eniglanud
13
10
329
boys
13.5-14.0
England
13
14
550
boys
14.3-14.7
Enugland
13
2.-Hemoglobin
TABLE
Age
No.
of subjects
Hgb
Levels
%,
(Gm.
among
as’.)
Men
Locatity
Ref.
19
12-19
-
13.8
Great
Britaini
15-19
-
14.2
Great
Britains
19
16-25
137
15.1
Hawaii
22
-
111
15.8
Cleveland
23
25
15.9
Philadelphia
24
411
15.2
Bostons
25
77
16.2
Sydnsev
26
51
17-23
17-25
19-28
15.6
Norway
-
539
245
16.0
15.7
U. S. A. and
Great
Britain
-
175
16.0
Lima
28
60
13.8
Canada
11
330
14.0
Winunsipeg
60-94
50
14.1
St.
60-98
41
13.9
Scotlansd
65-80
73
13.1
U. S. A.
29
69-91
50
12.6
U.
S.
A.
30
160
14.3
U.
S.
A.
31
19-30
16-59
‘
50-79
50-97
60-104
jects
were
ins tlse
studied
during
the
early
part
of the
winter,
27
Europe
2, 3
13
6
Louis
5
4
and
the
adults
later
in the
winter
and
sprinsg.
the
With
provide
drawn
help
of the
children
from
each
Those
from
universities,
6
to
Halifax
14 to
was
a
with
disorders
folks’
homes.
welfare
class
2() years
Capillary
into
of
Service,
a variety
were
age
the oldest
schools
its high
studensts
among
six
were
of socio-econsomic
them
schools,
would
wisich
would
Subjects
hospitals,
expected
be
choseni
groups.
to have
were
colleges,
and
a better
than
background.
wide variety
likely
Many
groups.
than
Medical
old from
in each school.
at least
socio-economic
There
School
14 years
grade
so that
average
taken
SEX
493
-
known
%,
(Gm.
a many
AND
-
6
nomic
Levels
AGE
4-14
-
old
WITH
6-13
6-14
anuy
LEVEL
those
blood
a calibrates!
from
of adult
to
were
affect
members
Ins general
usually
the
pipet,
adults
of the
finger
collected
were
some
were
and
were
ins surveys
and
There
hemoglobins
of clubs
studied
a puncture
Sahli
subjects.
the
societies,
more
of this
tip
was
ins a few
invalids
excluded.
among
Some
including
healthy
them,
were
some
and
but
residents
of
in a better
the
of
better
socio-eco-
kind.
used.
A sample
nmilliliters
of 20 cu.
of water
mm.
was
in a test
tube
HAWKINS,
No.
of subjects
A ND
Hgb
Ierels
%,
tGm.
1001
LEOXA
liD
among
hlonuen
Locality
av.)
Ref.
12-19
12.8
Great
Britaits
19
15-19
13.6
Great
Britain
19
32
12-19
258
12.2
13.0
15-22
48
44
Mi nsnsesot a
Cleveland
13.6
iIi55iS5il)l)i
17-21
1080
12.0
Toronto
17-24
4550
13.4
Nortlu
23
33
central
17-22
161
13.8
Amherst,
17-25
52
13.2
Linscolns,
17-26
352
13.8
Saskatoon,
18-23
25
13.5
Philatlelphia
17-68
403
14.0
U.
19-30
S.
U.
S.
10
34
A.
Mass.
35
Neb.
36
Sask.
24
A.
ansd
2, 3
Europe
14.1
Norway
275
13.2
Lincoln,
480
13.8
Great
64
12.7
Cansada
175
13.6
60-90
50
13.7
60-98
48
13.2
Winnipeg
St. Louis
Scotland
65-80
27
12.5
U.S.
A.
29
66-104
50
11.7
U. S.
A.
30
60
17-86
50-79
50-97
marked
to the
at
10 ml.
10 ml.
At the
nsark
with
spectrophotometer.
mination
the
K,
3.-Hemoglobin
TABLE
Age
SPEC
of
laboratory
water,
This
the
was
described
had
Collier.7
been
36
Britains
13
11
6
5
4
with
(lensity
of the
by
concentration
treated
optical
is ans application
hemoglobin
hemoglobin
this
arid
27
XCI).
ferricvanide
and
at 540
mM in a Coleman
read
cyanmethemoglobins
It
was
method
standardized
determinetl
cyanide,
from
against
the
iron
for
ea(’h
diluted
model
for
the
blood
constent
14
deter-
of which
and
oxygen
capacity.
RESULTS
The
hemoglobin
in table
values
4 and
Among
the
average
figure
children
of about
Gm. among
for higher
arrausged
accordiisg
to age
sex
are
preseusted
1.
6 to
13 Gm.
the oldest.
values
to
per
14 years
Up to about
occur
amoisg
amomig the boys.
The average
was the same,
13.5 Gm. per
old
100 ml.
value
100
the
values
of blood
imscreased
amomsg
12 years of age
the girls,
hut
the
there
with
age
youusgest
from
an
to about
14
w’as possibly
after
that
for both
boys amsd girls
ml. It may
be of itsterest
a temsdeuscy
they
were
6 to 14 years
to msote that
higher
of age
many
of the girls had started
to memsstruate
at about
11 years
of age. Ams examimsation
of the distribution of hemoglohins
values
amomsg
these
childrems
showed
that
40
per
cent
of them
were
betw’eems
13 ausd
14 Gm., 31 per ceust of them
beiusg higher
and 28 per cent low’er. No doubt
this slight
positive
skewness
w’as a reflectioms
of
the tendency
toward
higher
values
with
increasimsg
age.
In
creased
In the
at
jects.
14
the
subjects
betweels
slightly
among
latter
the average
years,
In
amid
individuals
14 amid
20
years
of age
the
the girls, amsd increased
rather
value
at 20 years of age was
represented
essemitially
15 to 20 years
of age
the
highest
iusclusive,
hemoglohims
markedly
5 per cent
value
the
average
values
amomsg
higher
shown
by
de-
the boys.
thams that
male
hemoglobius
suls-
value
1002
VARIATION
OF
4.-l’aria(ion
TABLE
HEMOGLOBIN
of Hemoqiobin
LEVEL
Levels
Population
with
WITH
.lge
of
AGE
and
Sex
AND
among
Representatives
,
Hgb.
Females
per
100 ml. of blood)
_______
________
(Gm.
No. of
subjects
.
Range
As’.
S.D.
per
tOO ml.
of blood)
_______________
Range
A.
S.D.
66
11.3-14.8
12.5
0.81
53
11.4-14.7
13.2
0.69
7
45
10.7-14.5
13.1
0.91
60
11.4-15.3
13.2
0.89
8
55
11.2-15.1
13.3
0.91
42
11.1-15.7
13.1
0.99
9
45
11.9-15.1
13.5
0.80
60
11.2-15.7
13.4
0.92
10
78
11.8-16.0
13.5
0.81
62
11.7-15.2
13.3
0.90
11
56
11.4-15.3
13.4
0.91
57
11.6-17.0
13.7
1.15
12
51
12.0-16.4
14.1
1.01
56
11.5-15.9
13.7
0.79
13
45
12.2-15.8
14.0
0.91
66
11.3-15.4
13.7
0.87
14
66
12.2-16.5
14.3
1.12
93
11.4-16.3
13.5
1.07
15
lOt)
11.4-17.4
14.4
1.05
154
10.5-15.7
13.3
0.9S
16
119
11.7-17.5
14.5
1.13
169
8.0-15.9
13.0
0.98
17
18
83
52
11.1-17.1
12.8-16.9
14.8
15.0
1.17
1.05
104
7.4-15.3
13.2
1.13
10.6-15.4
12.9
0.82
19
39
12.8-16.5
14.9
0.96
44
10.3-14.3
12.5
0.87
20
11)
12.8-17.5
14.9
1.05
21
11.3-14.1
13.2
0.75
57
21-30
83
12.1-18.0
15.1
1.22
44
9.0-14.4
12.7
1.14
31-40
23
12.3-17.5
14.6
1.35
39
11.0-16.2
13.2
0.92
41-50
23
11.8-16.8
14.7
1.26
39
10.2-16.5
13.2
1.30
51-60
65
8.1-16.9
14.4
1.31
41
9.6-16.3
13.1
1.32
61-70
51
8.4-17.4
13.9
1.59
55
7.7-15.6
12.9
1.33
71
33
8.3-16.1
11.1-15.4
13.0
13.0
1.45
1.24
10.6-12.6
11.4
0.95
71-80
71
81-90
28
8.9-17.1
8.9-15.8
13.4
12.4
1.59
1.73
91-100
3
8.9-14.3
11.2
2.18
4
6-14
510
10.7-16.5
13.5
1.00
549
11.1-17.0
13.5
0.96
15-20
421
11.1-17.5
14.6
1.12
549
7.4-16.3
13.2
1.04
326
8.3-16.5
13.0
1.20
1424
7.4-17.0
13.3
1.07
377
8.1-18.0
14.1
1.65
8.1-18.0
14.0
1.23
6-94
6-98
for
males
per
cemit.
of the
1308
.
was
14.6
The
distributions
males
16
Gm.;
per
ceist
and
Its the
13.0
and
3
had
99
per
case
Gm.
ceust
thereafter
its
of the
of
arid
for females
also
reflected
12 amid
females
amsy
its
age
for
had
very
little.
decade
succeedimsg
amid
levels
Gm.,
sex
81
a differetsce
differemsce
per
of 10
: 98 per
ceist
between
13 amid
16 Gm.,
and
of 14.1 Gm.
the values
in
tables
cent
10 and
between
of age the
be compared
ratsges
those
its youmsger
third
Gm.,
17
13.2
the
93
15 Gm.
Gm.
12.7
showus
differed
or
het.weeui
differemsces
ins the
those
ml.,
100
of values
of those
above
20 years
for w’omen
cams hardly
because
those
per
11 ausd
value
of
Gm.
levels
betw’eens
average
group
(Gm.
___________
6
21-98
for
Hgb.
,
No. of
subjects
21-94
ansy
of the
Halifax
Males
Age
SEX
are
its the
yearly
Amotsg
was
decade.
higher
insvolved.
third
age
the
averages
with
decade
groups.
mets
the
thami
Decreases
Among
that
the
of life
w’as
The
averages
average
value
men
2
women
the
lower
than
for decades
of 15.1 Gm.
its amsy youmiger
its hemoglobits
for
yearly
values
age
among
HAWKINS,
SPECK,
AND
LEONARD
1003
a
0
0
17
‘.
16
P4.1.
Av.±S.D
‘ F.sI.
#{149}
II 11IF
flifflh1fl
j;
10
#{149}
6
7
I
8
9
10 II
1213
14
1516
17181920
I
I
i
i
i
2l..3O3l..4O415O5I-6O6I..7O7I-8O81-9O
I
AGE
FIG.
-The
1
t
rensd
population
of Halifax.
the
w’ere
meis
men
values
of age,
amomsg
amsd 15 Gm.
Its w’omeis
per
they
values
those
and
mets
temided
became
amid
2 amid 3 are
ims tables
represerut
the
fifth
up
womemi
thaus
those
amousg
were
the
its
hue
I
70
its
years
tise
tsimstls
vomeus.
typi(’ally
case
Amousg
about
amid
occurriung
amomsg the
13
Gm.
The
differeusce
greater’
of
decade.
to
smaller,
of age
at ives
slsowns.
much
60 years
100 ml., the higher
values
were
typically
about
among
after
amousg
to be lower
20
sex
are
marked
thams
differemices
l)etw-eems
arud
tleviatiotss
more
highem’
the
its mets
wit hi age
stanutiard
amsd
comssiderahly
thereafter
values
ansd
progressive
values
globimi
values
Averages
were
1)1St
decade
of hemoglol)inu
Hemo-
l)etweeus
youmsger
14.3
sul)jects.
l)etweeus
of mets
than
these
of womeus.
DiscUssIoN
The
average
childrems
age
group.
these
A tremid
The
the
Pett,
agree
hemoglobin
13.5
the
with
(.m.
highest
some
imicreases
of what
Aim amsswer
Hanley,
amid
a group
those
which
Hanley’5
rem’
100
which
13
to
14
iuscrease
its l)oys
of
l)lood
reported
its
iusdicatimig
that
Gm.
per
age,
14 yeam’s
but
old
100
fom’ this
betweems
ml.
Other
lower
has
Flalifax
for
beets
with
6 to
ml.
have
others2
fm’om
the same
thams ours
fell
of
children
Perkimss1m
below’
level
tsot
oms the
1)asis
a thousatid
11.9
the
same
5 to
11
per
value
100
as the
old
its
of
arranged
999
(10.7
ims a histogram.
each
bar
of
the
Gm.
for
iii
curve
amid
distt’ibutiomi
British
its-
\.ttlIl(s
l)eets
‘#{176}-
reported
could
represeust.
Iow’ei’
limit
of normal
w’as
extemsded
Our
were
two
Gm.
17.0
drawus
to
made.
values
j)(
suggested
from
data
extremes
for
one
axis
time
the
ots
Halifax
six
omitted
girl).
which
amsd
examimsa-
the
ots
that
Pett
among
through
the
is im-
ma\!
amsemia.
distributed
the
(,lsildrems
of hemoglobius
Columbia,
ml.
amid
in
speculatiomss
Saskatchewams.
omse boy
A smooth
diagram,
ausemia
but
of the
childm’eis
Gm.
years
represemsts
possii)le,
were analyzed
as follow’s.
The values
fallimsg hetweems
12 and
17 Cm.,
w’ith
total
of
lsemoglobims
is of course
of over
deduced
children
intervals
top
is among
have
imsdicated
tow’ard
higher
values
questioms
amomig
the
results
of
value
old
England.13
port.amst.
tioms
14 years
Our
ages
vestigatiomss
from
hemoglobin
6 to
class
out
They
middle
the
of
were
of the
hemo-
1004
globin
VARIATION
OF
were
represemited.
values
Its limits
were
raisge
of values
would
12 arid
LEVEL
This
appear
to
15 Gm.
This
insformatiomi
average
hemoglobims
might
were
vere
in
AND
a slight
which
w’ho
use
however,
per 100
AGE
showed
Gm.,
h)e of little
distributioms
w’as such,
levels
below
12 Gm.
WITH
curve
at 11.1 Gm. amid 16.8
among
the 997 subjects
therefore
level.
The
hemoglobims
hEMOGLOBIN
SEX
positive
skewness.
also
the
limits
of the
a procedure
to
defimie
Such
comssidered.
attempt
an
that
5 per
ml. of blood,
be of more
the
anemic
cemit of the childrems
had
aisd 87 per cent between
use
thiuskiisg
iii
about
amsemic
levels.
The
w’omems
for
14 to 20 years
young
showms
girls
as young
tow’ard
as
14,
arid
decrease
other
ralues
surveys.1’
which
10.
each decade
of life
indicatimig
a virtual
many
of
value
mets,
betw’eems
leveliisg
groups
to be high compared
males
its this period
Halifax
subjects
the same
25
years
The
old
the
average
showed
13.9
iiscreases
Gm.
was
value
Youmsg
the
mens
globin
value
which
w’as
Its the
The
levels.
The
this
20 to 30
by
value
Pet.t
of
those
group
in
13.2
subjects,
Gm.
Gm.
its
authors
Halifax
15 to 20 years
were
so distributed
12 Gm. per 100
arid over.
These
small
degree
ml.
that
aisd
figures
of vamiatioms
20 years of age w’as remarkable.
but
it was
of age
how’ever,
amid
might
be
its hemoglobin
per
same
in
years
to 30.
old
This
its amsy decade
of life.
average
hemo-
as that
values
hemoglobirs
values,
ramiged betw’eems
14.2 Gm.
for the
per
cent
proportioms
among
highest values amomsg
to
last
20’s.
the
attempts
ml.
100
subjects
14
20
highest
95 amid 100
of use
Gm.
to
imito the
inclusive,
the
values
amid increases
this
group
of
essemstially the same
deviatioms,
12.2 amid
betw’eels
over,
The
its males
maimstaimsed
as mimsus arid plus one standard
per 100 ml. for the males,
amid
values
13
from
the
reported
Catsadian
mcmi
showed
Halifax
of those
14.9
irs boys
foumsd
also
for
off
with
those
of more
that
for those
17 to
amousg
youmsg
in
100 ml.,
by Pett
a leveling
of blood
of age,
noted
womemi
Gm. per
obtained
most
higher,
Ogilvietm’
decrease
been
Halifax
ml.
than
compare
The
imsdicated
years
was
and
of army of the male
subjects,
at the age of 17 arid
Halifax
100
low’er
is a
1)etw’een
has
were
12.7 to 13.2
age of 20. Values
also
there
would
group
compare
more
favorably
is supported
by the fact
amid 14.5
w’hich
age
age
If
range.
amotsg
per
20.
to those
in the five precedimsg
years,
of life would
be expected,
so that
reached
expressed
15.7 Gm.
showed
10 Gm.
highest
ins
young
values
w’omeis
age
this
of Camsada
From
thams
subjects
same
values
was
19,
for
of average
young
Halifax
Cm.
2).
of blood
older
in
the
w’ithims
parts
ams average
17 to
these
msearly
of 14.6
found
from
in those
for
hemoglobims
values
some
values
hemoglobims
proh)ab)ly
would
age ramige. This
hemoglobims
ramsge
of age imsclusive,
(table
tended
amotsg
nearly
ml.
the
20 amid 90 years
off at about
the
15 to 20 years
cOmparal)le
015
100
w’e observed
and Ogilvie#{176} omi womems in various
through
the middle
years
of life.
The average
hemoglobims
value
youlsg
Gm.
imiclude
its more
Average
11
per
w’as withims
hemoglobims
those
ages,
thems the average
favorably
with those
for others
its hemoglobins
13.2
Umsited
States,
amid Great
Britain
svhich
are
comparable
groups
represemsted
in this table
table
tendeiscy
in
of
its Halifax
womems its Camsada,
the
3. Very
few of the
its
include
value
of age
women
females
the
define
and
females.
of the
of
to
13.5
males
females
ansemic
after
about
were
shown
SPECK,
HAWKINS,
AND
by those
between
10 and 14 years
of age.
pause
affected
the hemoglobin
level.
In men the progressive
resulted
in the highest
were
30
50,
then
hemoglobin
appeared
values
This
surveys46
which
supplies
between
have
further
Whether
may
the
higher
follow’ed
by a fall,
values.
men
been
evidence
or not
to note that
in the liver,
was
decreasimig
amid
to be the result
of decreasing
men
after
middle
age has
in
this
was
progressively
values
There
1005
iso evidemice
that
the
memso-
increase
ims hemoglobin
through
childhood
amid youth
values
beimig showms in the 20’s, whets the lowest
values
by women.
shown
and
LEONARD
it has
The
womems
to above,
a levelimsg
off betw’eems
decreasimsg
with
differemice
advamscimsg
levels
in men.
beers irsdicated
referred
for
possibly
age
imi
therefore
This trend
its hemoglohims
the results
of previous
in
amid the
material
of this
report
it.
any
connection
w’ith
hemoglobin,
it might
be of iusterest
there
is a difference
betw’een
the sexes in the (‘omiceustratioms
of iromi
but it varies
with the species.tm6’
‘
In rats it is higher
ins females,
and
be
associated
liver
with
sex
hormonses.mt
17
In the
case
of humauss,
mets
have
iron.’8
SuIIAIsY
During
the winter
and spring
of 1952-53
made
in Halifax
among
1308 male subjects
6 to 94 years
of age.
Among
children
6 to 14 years
old the
14 Gm. per 100 ml. of blood,
and there
a survey
of hemoglobims
values
was
6 to 98 years
of age, amid 1424 female
subjects
the
sexes.
In
The
girls
slightly,
average
between
reaching
was
au
20 years
They
were
female
to
of age,
the
20
13 Gm.
about
the
of
per
100
In
lowest
subjects
itscreased
essentially
boys
amid the
sexes
these
characteristic
arid
from about
13 to about
rio differemsces
between
girls
was
13.5
Cm.
age the hemoglobims
values
ml. In boys of correspomsdimsg
both
remaimied
the
male
both
years
15 Gm.
and
essentially
and
for
and
about
increase
about
value
14
values
were
the
of army age
highest
values
were
of the
third
showms
respectively
decreased
ages there
attaimsed
decade
at
of life.
h)y
the
group.
Hemoglobin
values in mcmi between
20 arid 60 years of age w’ere typically
to 15 Gm. per 100 ml., the higher
values
tensdimsg
to occur
amouig
the youusger
men.
After
the fifth decade
there
w’ere progressive
amid marked
decreases
to ami
14.5
average
In
of 12.4
women
mained
in men
20
between
years
from
near
13 Gm.
per
80 arid
of
100
age
presentate
un
studio
of age.
the
average
hemoglobins
values
re-
ml.
SUMMARIO
Es
90 years
onsw’ard
IN
del
statistic
INTERLINGUA
valores
hemoglobinic
obtenite
durante
le
e primavera
de 1952/53 a Halifax in Nova Scotia ab 2732 individuos1308 masculin
de etates
ab 6 a 98 annos
e 1424 feminin de etates ab 6 a 94 annos.
In juvenes
inter
6 e 14 annos
le valores
cresceva
ab circa
13 a cim’(’a 14 g per
hiberno
100
ml
de sanguine.
constatate
In
In iste gruppo
de
le sexos.
Le valor
medic
inter
14 e 20 annos
deetate
inter
pueras
levemente
usque
a circa
13 g per
100 ml
etate
nulle
pro pueros
le valores
de
sanguine.
differentia
essential
e pueras
esseva
de hemoglobina
In pueros del
esseva
13,5
g.
decresceva
mesme
etates
1006
VARIATION
ii habeva
un
attingite
del
HEMOGLOBIN
accrescimento
usque
de circa
20 annos.
a! etate
vita
OF
e representava
LEVEL
a
15 g.
Illos
respectivemente
WITH
In
AGE
ambe
AND
sexos
SEX
iste
remaneva
typic
durante
le minimo
e Ic maximo
valores
esseva
le tertie
decade
inter
le gruppos
de etate del duo sexos.
Le
valores
de hemoglobina
14,5 a 15 g per
typicamente
occurrer
le individuos
in
in masculos
100
plus
ml
de
juvene.
inter
30
sanguine.
Post.
e 60
Le
le quimste
e marcate
decrescimentos
usque
al valor medic
de etate.
In feminas
post 20 annos
de etate
Ic valores
annos
valores
decade
de
12,4
de
plus
etate
alte
il habeva
pro
esseva
tendeva
a
progressive
homines
inter
80 e 90
annos
presso
a 13 g per
medic
de hemoglobina
persisteva
100 ml de sanguine.
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