Obrazec za opis predmeta SLO/ENG

Transcription

Obrazec za opis predmeta SLO/ENG
Termodifuzijska tehnika
Predmet:
Course title:
UČNI NAČRT PREDMETA / COURSE SYLLABUS
Termodifuzijska tehnika
Stagewise Processes
Študijski program in stopnja
Study programme and level
Študijska smer
Study field
Letnik
Academic year
Semester
Semester
1.
zimski
Autumn
Kemijska tehnika / 2. stopnja
Chemical Engineering / 2nd level
Vrsta predmeta / Course type:
Obvezni / Obligatory
Univerzitetna koda predmeta / University course code:
Predavanja
Lectures
Seminar
Seminar
Sem. vaje
Tutorial
60
Nosilec predmeta / Lecturer:
Jeziki /
Languages:
Lab. vaje
Laboratory
work
50
Teren. vaje
Field work
Samost. delo
Individ. work
ECTS
160
9
Željko Knez
Predavanja / Lectures: slovenski / Slovene
Vaje / Tutorial: slovenski / Slovene
Pogoji za vključitev v delo oz. za opravljanje
študijskih obveznosti:
Osvojeni pojmi in osnovna znanja s področij fizike,
fizikalne kemije, termodinamike in prenosnih
pojavov.
Prerequisits:
Vsebina:
 Uparjanje. Procesni parametri. Tipi uparjalnikov.
Postopki
uparjanja.
Dimenzioniranje
uparjalnikov.
 Kristalizacija. Osnove kristalizacije. Ravnotežje
pri kristalizaciji. Hitrost tvorbe kristalnih jeder in
rasti kristalov. Dimenzioniranje kristalizatorjev.
 Destilacija. Ravnotežje pri destilaciji. Vrste
destilacij. Rektifikacija. Vrste rektifikacij.
Rektifikacijske naprave. Dimenzioniranje kolon.
 Ekstrakcija trdno-tekoče. Hitrost ekstrakcije.
Prenos snovi pri ekstrakciji trdnih snovi. Vrste
ekstraktorjev. Dimenzioniranje ekstrakcijske
baterije.
 Ekstrakcija tekočih zmesi. Osnove. Postopki
ekstrakcije tekoče-tekoče. Aparati za ekstrakcijo
tekočih
zmesi.
Hitrost
ekstrakcije.
Content (Syllabus outline):
 Evaporation. Process parameters. Types of
evaporators. Processes of evaporation. Design of
evaporators.
 Crystallization. Fundamentals of crystallization.
Equilibrium in crystallization. The rate of crystal
core formation and crystal growth. Design of
crystallizators.
 Distillation. Equilibrium in a distillation.
Distillation types. Rectification. Rectification
types. Rectification apparatus. Design of column.
 Solid-liquid extraction. Extraction rate. Mass
transfer in solid extraction. Extractor types.
Design of extraction battery.
 Extraction of liquid mixtures. Fundamentals.
Processes of liquid-liquid extractions. Extraction
apparatus for liquid mixtures. Extraction rate.
Basic knowledge of physics, physical chemistry,
thermodynamics and transport phenomena.
1
Dimenzioniranje
protitočne
ekstrakcijske
baterije.
 Tehnologije s fluidi nad kritično točko
Ekstrakcijski procesi s superkritičnimi fluidi.
Biokemijske reakcije v superkritičnih fluidih.
Uporaba superkritičnih fluidov za mikronizacijo.
 Sušenje. Namen in potek sušenja. Metode
sušenja. Osnove psihrometrije. Mehanizem
sušenja s hlapljenjem. Vrste sušilnikov.
Dimenzioniranje sušilnikov.
Design of counter current extraction battery.
 Technologies with fluids above critical point.
Extraction processes with supercritical fluids
Biochemical reactions in supercritical fluids.
Application
of
supercritical
fluids
for
micronization.
 Drying. Purpose and procedure of drying. Drying
methods. Fundamentals of psihrometry. The
mechanism of drying with evaporation. Dryer
types.
Laboratorijske vaje:
V okviru laboratorijskih vaj se izvaja tankoslojno
uparjanje, diferencialna destilacija, rektifikacija,
ekstrakcija trdno-tekoče, in sušenje.
Laboratory work:
Laboratory work includes thin-layer evaporation,
differential distillation, rectification, solid-liquid
extraction, and drying.
Temeljni literatura in viri / Readings:
 Ž. Knez, M. Škerget, Termodifuzijski separacijski procesi, FKKT, Maribor, 2009.
Dodatna priporočena literatura:
 K. Sattler, H. J. Feindt, Thermal Separation Processes: Principles and Design, VCH, Weinheim, 2007.
 Paul T. Anastas, Carlos A. M. Afonso, João Pedro G. Crespo, Green Separation Processes:
Fundamentals and Applications, VCH, Weinheim, 2005.
 V. Anikeev, M. Fan, Supercritical Fluid Technology for Energy and Environmental Applications,
Elsevier, 2014.
Cilji in kompetence:
Predmet sodi med osnovne kemijsko inženirske
predmete. Kot sinteza kemijske in inženirske
termodinamike, transportnih fenomenov ter
masnih in toplotnih bilanc zagotovi osnovno
znanje, ki ga inženir-tehnolog potrebuje pri
vodenju in načrtovanju separacijskih procesov ter
naprav. Predmet razvija študentu sposobnost
analize in sinteze kompleksnih kemijsko
tehnoloških sistemov.
Objectives and competences:
The subject is one of the fundamental subjects in
Chemical engineering. As synthesis of chemical and
engineering
thermodynamics,
transport
phenomena, as well as mass and heat balance, it
assures the basic knowledge for an engineertechnologist, which is needed in control and design
of separation processes and apparatus. The subject
develops the student ability of analysis and
synthesis of complex chemical technological
systems.
Predvideni študijski rezultati:
Znanje in razumevanje:
Zmožnost načrtovanja destilacijskega, uprajalnega
ali ekstrakcijskega sistema.
Uporaba ustreznih procesnih parametrov v
povezavi z načrtovanim sistemom.
Intended learning outcomes:
Knowledge and understanding:
Design of distillation, evaporation or extraction
system.
Application of proper process parameters for a
defined process analysis.
Prenesljive/ključne spretnosti in drugi atributi:
Vsebina predmeta je povezana z ostalimi predmeti
na smeri Kemijska tehnika in podaja znanja,
potrebna za razumevanje vsebin, ki so zajeta npr.
pri predmetu Bioseparacijska tehnika in biokataliza.
Transferable/Key Skills and other attributes:
The subject is connected to other subjects on the
direction Chemical engineering and gives the
knowledge which is necessary for understanding
other subjects such as Bioseparation engineering
and biocatalysis.
Metode poučevanja in učenja:
- predavanja
- laboratorijske vaje
Learning and teaching methods:
lectures
laboratory work
2
Načini ocenjevanja:
Način (pisni izpit, ustno izpraševanje,
naloge, projekt)
Izpit je opravljen, če so pozitivno
opravljene vse naslednje obveznosti:
 pisni izpit
 ustni izpit
 laboratorijske vaje
Delež (v %) /
Weight (in %)
60
30
10
Assessment:
Type (examination, oral, coursework,
project):
Student has to pass successfully the
following obligations:
 written examination
 oral examination
 laboratory work
Reference nosilca / Lecturer’s references:
KNEZ, Željko, ŠKERGET, Mojca, KNEZ HRNČIČ, Maša. Principles of supercritical fluid extraction and applications in
the food, beverage and nutraceutical industries. V: RIZVI, Syed S. H. (ur.). Separation, extraction and concentration
processes in the food, beverage and nutraceutical industries. Oxford [etc.]: Woodhead Publishing Limited, 2010,
str. [3]-38.
REIBE, Christian, KNEZ, Željko, WEIDNER, Eckhard. A new high-pressure micronisation process for the gentle
processing of high molecular mass gelatine. Food and bioproducts processing, ISSN 0960-3085, 2012, vol. 90, no. 2,
str. 79-86, doi: 10.1016/j.fbp.2011.02.001.
KNEZ, Željko, MARKOČIČ, Elena, LEITGEB, Maja, PRIMOŽIČ, Mateja, KNEZ HRNČIČ, Maša, ŠKERGET, Mojca.
Industrial applications of supercritical fluids : a review. Energy, ISSN 0360-5442, 2014, str. 1-9, doi:
10.1016/j.energy.2014.07.044.
KNEZ, Željko, MARKOČIČ, Elena, KNEZ HRNČIČ, Maša, RAVBER, Matej, ŠKERGET, Mojca. High pressure water
reforming of biomass for energy and chemicals : a short review. The Journal of supercritical fluids, ISSN 0896-8446,
2014, vol. , str. 1-8, doi: 10.1016/j.supflu.2014.06.008.
RAVBER, Matej, KNEZ, Željko, ŠKERGET, Mojca. Simultaneous extraction of oil- and water-soluble phase from
sunflower seeds with subcritical water. Food chemistry, ISSN 0308-8146, 2015, vol. 166, str. 316-323, doi:
10.1016/j.foodchem.2014.06.025.
3
Načrtovanje procesov
Predmet:
Course title:
UČNI NAČRT PREDMETA / COURSE SYLLABUS
Načrtovanje procesov
Process Design
Študijski program in stopnja
Study programme and level
Kemijska tehnika / 2. stopnja
Chemical Engineering / 2nd level
Študijska smer
Study field
Letnik
Academic year
1.
Vrsta predmeta / Course type:
Semester
Semester
zimski
Autumn
Obvezni / Obligatory
Univerzitetna koda predmeta / University course code:
Predavanja
Lectures
45
Seminar
Seminar
Nosilec predmeta / Lecturer:
Jeziki:
Languages:
Sem. vaje
Tutorial
30
Lab. vaje
Labor work
Teren. vaje
Field work
Samost. delo
Individ. work
105
ECTS
6
Zorka Novak Pintarič
Predavanja / Lecture: slovenski / Slovene
Vaje / Tutorial: slovenski / Slovene
Pogoji za vključitev v delo oz. za opravljanje
študijskih obveznosti:
Potrebno je znanje iz termodinamike, prenosa
toplote in snovi ter osnovno znanje iz separacijske
in reakcijske tehnike.
Prerequisites:
Vsebina:
Strategije načrtovanja in integracije kemijskih
procesov (hierarhična, termodinamska,
algoritemska).
Modeli za oceno termofizikalnih lastnosti v
simulatorjih.
Načrtovanje in simulacija procesnih podsistemov:
- reakcijske poti, reaktorji in reaktorska omrežja,
- separatorji in separacijska omrežja.
- omrežje reaktor-separator-obtok.
Procesna integracija:
- integrirana omrežja toplotnih prenosnikov,
- toplotna integracija reaktorjev, separatorjev in
separacijskih omrežij,
- toplotni stroji in toplotne črpalke,
- vpliv toplotne integracije na obtok in celotno
presnovo reaktantov,
- vodna integracija.
Načrtovanje šaržnih procesov.
Načrtovanje integriranih, trajnostnih procesov.
Content (Syllabus outline):
Strategies for chemical process design and
integration (hierarchic, thermodynamic,
algorithmic).
Models for thermophysical property data in process
simulators.
Design and simulation of process subsystems:
- reaction paths, reactors and reactor networks,
- separators and separation sequencing,
- reactor-separator-recycle networks.
Process integration:
- heat exchanger networks,
- heat integration of reactors, separators and
separation networks,
- heat engines and heat pumps,
- interactions of heat integration, purge-to-recycle
ratio and overall conversion of reactants,
- water integration.
Design of batch processes.
Design of integrated sustainable processes.
Knowledge about thermodynamics, heat and mass
transfer and basic knowledge about separation and
reaction engineering is required.
4
Sprotno reševanje domačih nalog.
Ongoing homework assignments.
Računalniške vaje:
Simulacije posameznih procesnih enot in procesnih
podsistemov.
Projektna naloga, procesna shema in simulacija
procesa.
Computer Exercises:
Simulation of process equipment and process
subsystems.
Process design project formulation, process flow
sheet simulation.
Temeljni literatura in viri / Textbooks:
 Z. Novak Pintarič, Načrtovanje in integracija procesov, zbrano gradivo. Univerza v Mariboru, Fakulteta
za kemijo in kemijsko tehnologijo, Maribor, 2014.
 Z. Novak Pintarič, Simulacija kemijskih procesov, zbrano gradivo. Univerza v Mariboru, Fakulteta za
kemijo in kemijsko tehnologijo, Maribor, 2014.
Dodatna priporočena literatura:
 R. Smith, Chemical Process Design and Integration, J. Wiley, 2005.
 W. D. Seider, J. D. Seader, D. R. Lewin: Product and process design principles: synthesis, analysis, and
evaluation. Second Edition, Wiley, New York, 2004.
 J. J. Klemeš (Ed.), Handbook of Process Integration (PI), Woodhead Publishing, Cambridge, 2013.
Cilji in kompetence:
Študent spozna konceptualno načrtovanje
kemijskih procesov, osvoji osnove procesno
sistemskega pristopa in integracije procesov s
poudarkom na hierarhičnih in termodinamskih
metodah.
Objectives and competences:
To acquaint students with conceptual design of
chemical processes.
To acquire process system engineering approach to
process design and integration, based on hierarchic
and thermodynamic methods.
Predvideni študijski rezultati:
Znanje in razumevanje:
Študent obvlada konceptualno načrtovanje
kemijskih procesov. Razume povezanost
podsistemov reakcija-separacija-obtok-toplotna
integracija. Razume vpliv toplotne integracije in
razmerja obtok/odtok na celotno presnovo
reaktantov. Spozna simulacijo procesov in
termodinamske metode za integracijo procesov.
Prenesljive/ključne spretnosti in drugi atributi:
Računalniško načrtovanje reaktorjev, separatorjev,
toplotnih strojev in črpalk, celotnih procesnih
shem. Razvijanje sposobnosti za skupinsko in
projektno delo.
Intended learning outcomes:
Knowledge and Understanding:
Students master the conceptual design of chemical
processes. They understand the interactions of
process subsystems, e.g. reaction, separation,
recycle and heat integration. Students understand
the tradeoffs between heat integration, purge-torecycle ratio, recycle ratio, and overall conversion of
reactants.
They are acquinted with simulation of process flow
sheets and process integration by thermodynamic
methods.
Transferable/key skills and other attributes:
Computer aided design and retrofit of reactors,
separators, heat engines, heat pumps, and process
flow sheets. Abilities to work in team.
Experience in executing large projects.
Metode poučevanja in učenja:
Aktivno poučevanje in učenje.
Individualne računalniške vaje.
Uporaba tujih jezikov in literature.
Skupinske računalniške vaje simuliranja,
integriranja, načrtovanja.
Pisanje in zagovor poročil iz posamičnih vaj in
skupinskega projektnega poročila.
Learning and teaching methods:
Active teaching and learning.
Individual work using computers.
Usage of foreign languages and literature.
Team-work in process design, simulation and
integration.
Writing and defence of individual work as well as
the team design report.
5
Načini ocenjevanja:
Izpit je opravljen, če so pozitivno
opravljene vse naslednje obveznosti:
 pisni računski izpit ali dva računska
testa
 izpit teorije ali dva testa teorije
 projektno poročilo
 domače naloge
Delež (v %) /
Weight (in %)
60
20
15
5
Računski test in test teorije se izvajata hkrati.
Vse domače naloge morajo biti rešene.
Assessment:
Student has to pass successfully the
following obligations:
 written exam (calculus) or two written
tests (calculus)
 Theory exam or two theory tests
 project report
 homeworks
Calculus test and theory test are performed
simultaneously. All homework assignments must
be completed.
Reference nosilca / Lecturer’s references:
NOVAK-PINTARIČ, Zorka, KRAVANJA, Zdravko. Suitable process modelling for proper multi-objective optimization
of process flow sheets. V: KLEMEŠ, Jiri (ur.), VARBANOV, Petar (ur.), LIEW, Peng Yen (ur.). 24th European
Symposium on Computer Aided Process Engineering : [ESCAPE-24, 15 to 18 June 2014, Budapest, Hungary],
(Computer aided chemical engineering, ISSN 1570-7946, 33). Amsterdam ... [et al.]: Elsevier, cop. 2014, str. 13881392. [COBISS.SI-ID 18172438]
NOVAK-PINTARIČ, Zorka, KASAŠ, Mihael, KRAVANJA, Zdravko. Sensitivity analyses for scenario reduction in flexible
flow sheet design with a large number of uncertain parameters. AIChE journal, ISSN 0001-1541. [Print ed.], Avg.
2013, vol. 59, iss. 8, str. 2862-2871, doi: 10.1002/aic.14061. [COBISS.SI-ID 16795926]
TOKOS, Hella, NOVAK-PINTARIČ, Zorka, GLAVIČ, Peter. Energy saving opportunities in heat integrated beverage
plant retrofit. Applied thermal engineering, ISSN 1359-4311. [Print ed.], Jan. 2010, vol. 30, no. 1, str. 36-44, doi:
10.1016/j.applthermaleng.2009.03.008. [COBISS.SI-ID 13122838]
TOKOS, Hella, NOVAK-PINTARIČ, Zorka. Synthesis of batch water network for a brewery plant. Journal of cleaner
production, ISSN 0959-6526. [Print ed.], Nov. 2009, vol. 17, iss. 16, str. 1465-1479, doi:
10.1016/j.jclepro.2009.06.009. [COBISS.SI-ID 13317910]
NOVAK-PINTARIČ, Zorka. Načrtovanje in integracija procesov : zbrano gradivo za predmet Načrtovanje procesov na
bolonjskem magistrskem programu Kemijska tehnika. Maribor: Fakulteta za kemijo in kemijsko tehnologijo, 2014.
[145] f., ilustr. https://estudij.um.si/mod/resource/view.php?id=21344, http://dkum.unimb.si/IzpisGradiva.php?id=44461. [COBISS.SI-ID 17583638]
NOVAK-PINTARIČ, Zorka. Simulacija kemijskih procesov : zbrano gradivo za vaje pri predmetu Načrtovanje
procesov na bolonjskem magistrskem programu Kemijska tehnika. Maribor: Fakulteta za kemijo in kemijsko
tehnologijo, 2014. [37] f., ilustr. https://estudij.um.si/mod/resource/view.php?id=21375, http://dkum.unimb.si/IzpisGradiva.php?id=44466. [COBISS.SI-ID 17583894]
6
Kemijska reakcijska tehnika II
Predmet:
Course title:
UČNI NAČRT PREDMETA / COURSE SYLLABUS
Kemijska reakcijska tehnika II
Chemical Reaction Engineering II
Študijski program in stopnja
Study programme and level
Kemijska tehnika / 2. stopnja
Chemical Engineering / 2nd level
Študijska smer
Study field
Letnik
Academic year
1.
Vrsta predmeta / Course type:
Semester
Semester
zimski
Autumn
Obvezni / Obligatory
Univerzitetna koda predmeta / University course code:
Predavanja
Lectures
45
Seminar
Seminar
Nosilec predmeta / Lecturer:
Jeziki /
Languages:
Sem. vaje
Tutorial
Lab. vaje
Labor work
30
Teren. vaje
Field work
Samost. delo
Individ. work
105
ECTS
6
Andreja Goršek
Predavanja / Lecture: slovenski / Slovene
Vaje / Tutorial: slovenski / Slovene
Pogoji za vključitev v delo oz. za opravljanje
študijskih obveznosti:
Potrebno je znanje iz materialov, termodinamike,
prenosa toplote in snovi ter osnovno znanje iz
separacijske in kemijske reakcijske tehnike.
Prerequisites:
Vsebina:
Predavanja:
Heterogeni reakcijski sistemi.
Bifluidne in fluosolidne reakcije.
Katalizirane reakcije.
Temperaturni učinki pri homogenih reakcijah in v
stopenjskih reaktorjih z nasuto plastjo.
Upor v porah katalizatorja in toplotni učinki.
Reaktor s fluidizirano plastjo.
Dezaktivirna kataliza.
Biokemijski reakcijski sistemi.
Načrtovanje reaktorjev (osnove, simulacija
procesnih operacij, modeliranje reaktorjev).
Izbira materialov (termodinamika in kinetika
plinske in elektrolitske korozije, protikorozijska
zaščita, pojavne oblike korozije).
Content (Syllabus outline):
Lectures:
Heterogeneous reaction systems.
Fluid-fluid and fluid-particle reactions.
Solid catalyzed reactions.
Temperature effects in homogeneous and packedbed reactors.
Catalyst pore resistance, heat effects.
Fluidised bed reactor.
Deactivating catalysis.
Biochemical reaction systems.
Reactor design (simulation of process operations,
reactor modelling).
Material selection (thermodynamics and kinetics of
gaseous/electrolytic corrosion, corrosion
prevention, and forms of corrosion).
Knowledge about materials engineering,
thermodynamics, heat and mass transfer and basic
knowledge about separation and reaction
engineering is required.
7
Računalniške vaje:
Modeliranje reaktorjev (mešalni, kaskadni, cevni),
kinetika radikalov, heterogena kataliza,
kopolimerizacija, porazdelitve bivalnih časov,
dinamično modeliranje).
Computer Exercises:
Reactor modelling (mixed flow, in series, plug flow),
kinetics of radicals, heterogeneous catalysis,
copolymerization, residence time distribution,
dynamic modelling.
Laboratorijske vaje:
Korozijska odpornost gradiv
Katalitski reaktor
Laboratory Exercises:
Corosion resistance of materials
Catalytic reactor
Temeljni literatura in viri / Textbooks:
 P. Glavič, Kemijska reakcijska tehnika, zbirka nalog z navodili in rešitvami, UM FKKT, Maribor, 2007.
 O. Levenspiel, Chemical Reaction Engineering, 3rd Ed., John Wiley and Sons, New York, 1999.
Dodatna priporočena literatura:
 P. Glavič, Gradiva, UM, FKKT, Maribor, 2006.
 H. Scott Fogler, Elements of Chemical Reaction Engineering, Prentice-Hall, London, 2005.
Cilji in kompetence:
Študent se seznani s heterogenimi reakcijskimi
sistemi. Dodatno spozna numerično modeliranje in
načrtovanje kataliziranih in nekataliziranih
reakcijskih sistemov, zahtevnejše vrste reaktorjev
in toplotne učinke v njih.
Izbira in uporaba gradiv v konstruiranju.
Propadanje gradiv in obvladovanje hitrosti korozije.
Sinteza znanj iz kemije, termodinamike, osnovnih
pojavov in operacij, varnosti in okolja, ekonomike.
Objectives and competences:
Student is introduced to heterogeneous reaction
systems together with modelling of catalytic and
non-catalytic reaction systems, more complex
reactors and their heat effects.
Selection and use of construction materials.
Corrosion and corrosion prevention in materials.
Synthesis of knowledge, acquired in: chemistry,
basic phenomena, thermodynamics, unit
operations, safety, environmental protection,
economics.
Predvideni študijski rezultati:
Znanje in razumevanje:
Razširitev znanja na kompleksne reakcijske sisteme
(več vzporednih, zaporednih, ravnotežnih,
kataliziranih reakcij), za katere so značilni
komplicirani izrazi za proizvodnost in posebni
načini kontaktiranja.
Intended learning outcomes:
Knowledge and Understanding:
Knowledge extension to complex reaction systems
(more parallel, series, equilibrium, and catalyzed
reactions) with more complicated rate expressions
and contacting patterns.
Prenesljive/ključne spretnosti in drugi atributi:
Razumevanje heterogenih reakcij, pravilna izbira
reaktorjev in modeliranje osnovnih ter zahtevnejših
tipov reaktorjev (prav tako osnovnih operacij).
Transferable/key skills and other attributes:
Understanding of heterogeneous reactions, choice
of right reactor and modelling of simple and more
complex reactors (basic unit operations).
Metode poučevanja in učenja:
Aktivno poučevanje in učenje.
Individualne računalniške vaje.
Uporaba tujih jezikov in literature.
Računalniške vaje modeliranja.
Learning and teaching methods:
Active teaching and learning.
Individual work using computers.
Usage of foreign languages and literature.
Computer exercises on modelling.
Laboratorijske vaje.
Pisanje in zagovor poročil iz posamičnih vaj.
Laboratory exercises.
Writing and defence of individual work.
8
Načini ocenjevanja:
Izpit je opravljen, če so pozitivno
opravljene vse naslednje obveznosti:
- računalniške vaje
- laboratorijske vaje
- pisni izpit
- ustni izpit
Delež (v %) /
Weight (in %)
20
10
40
30
Assessment:
Student has to pass successfully the
following obligations:
- computer exercises
- laboratory
- writen exam (problem solving)
- oral exam
Reference nosilca / Lecturer’s references:
KRIŽAN, Janja, PETRINIĆ, Irena, GORŠEK, Andreja, SIMONIČ, Marjana. Ultrafiltration of oil-in-water emulsion by
using ceramic membrane : Taguchi experimental design approach. Central European Journal of Chemistry, ISSN
1895-1066, Feb. 2014, vol. 12, iss. 2, str. 242-249, ilustr., doi: 10.2478/s11532-013-0373-6. [COBISS.SI-ID
17373718].
PEČAR, Darja, GORŠEK, Andreja. Oxidation of menthol : reaction-rate determination based on thermodynamic
profiles. Chemical engineering communications, ISSN 0098-6445, 2014, vol. 201, iss. 11, str. 1548-1554.
http://www.tandfonline.com/doi/full/10.1080/00986445.2013.819353#.U6E-jU-KDq4. [COBISS.SI-ID 17918998].
ZAJŠEK, Katja, GORŠEK, Andreja, KOLAR, Mitja. Cultivating conditions effects on kefiran production by the mixed
culture of lactic acid bacteria imbedded within kefir grains. Food chemistry, ISSN 0308-8146. [Print ed.], Jan. 2013,
vol. 139, iss. 1-4, str. 970-977, doi: 10.1016/j.foodchem.2012.11.142. [COBISS.SI-ID 16645142].
GORŠEK, Andreja, TRAMŠEK, Marko. Production of unique naturally immobilized starter : a fractional factorial
design approach towards the bioprocess parameters evaluation. V: MATOVIC, Darko (ur.). Biomass - detection,
production and usage. Rijeka: InTech, cop. 2011, str. 185-200.
http://www.intechopen. com/source/pdfs/19074/InTechProduction_of_unique_naturally_immobilized_starter_a_fractional_factorial_design_approach_towards_the_biop
roces s_parameters_evaluation.pdf. [COBISS.SI-ID 15454998].
LEŠER, Tadej, GORŠEK, Andreja. Study of enamel frit melting kinetics. Glass technology, ISSN 0017-1050, Oct. 2013,
vol. 54, no. 5, str. 199-203. [COBISS.SI-ID 17385238].
9
Dinamika in optimiranje procesov
Predmet:
Course title:
UČNI NAČRT PREDMETA / COURSE SYLLABUS
Dinamika in optimiranje procesov
Process Dynamics and Optimization
Študijski program in stopnja
Study programme and level
Kemijska tehnika / 2. stopnja
Chemical Engineering / 2nd level
Študijska smer
Study field
Letnik
Academic year
1.
Vrsta predmeta / Course type:
Semester
Semester
zimski
autumn
Obvezni / Obligatory
Univerzitetna koda predmeta / University course code:
Predavanja
Lectures
60
Seminar
Seminar
Sem. vaje
Tutorial
Nosilec predmeta / Lecturer:
Jeziki /
Languages:
Lab. vaje
Labor work
45
Teren. vaje
Field work
Samost. delo
Individ. work
165
ECTS
9
Zdravko Kravanja
Predavanja / Lecture: slovenski / Slovene
Vaje / Tutorial: slovenski / Slovene
Pogoji za vključitev v delo oz. za opravljanje
študijskih obveznosti:
Osnove dinamike procesov, linearnega (LP) in
nelinearnega programiranja (NLP).
Prerequisites:
Vsebina:
Matematično modeliranje in reševanje: dinamično
modeliranje nekaterih osnovnih procesnih operacij,
numerična integracija in reševanje diferencialnoalgebrskih sistemov enačb, dinamična simulacija.
Content (Syllabus outline):
Mathematical modeling and solution: dynamic
modeling of some basic process unit operations,
numerical integration and solution of differentialalgebraic systems of equations, dynamic simulation.
Dinamika procesov:
 Uvod in načrtovanje sistemov z eno
spremenljivko: povratnozančna regulacija in
frekvenčna analiza, sistemi z velikim mrtvim
časom in inverznim odzivom, večzančne
strukture, vnaprejšnja in razmerna regulacija,
adaptivna in inferenčna regulacija.
 Načrtovanje sistemov z več spremenljivkami:
alternativne regulcijske konfiguracije,
medzančne interakcije in ukrepi, osnove
načrtovanja regulacijskih sistemov za celotne
obrate.
 Osnove načrtovanja računalniških regulacijskih
sistemov in optimiranja v realnem času.
Optimiranje in integracija procesov:
Basic knowledge of process dynamics, linear (LP)
and nonlinear programming (NLP).
Process Dynamics:
 Introduction and design of single variable
control systems (SISO): feedback control and
analysis of frequency response, systems with
large dead time or inverse response, multiple
loop configurations, feedforward control and
ratio control, adaptive and inferential control.
 Multivariable control systems (MIMO):
alternative control configurations, interaction of
control loops, relative-gain array and decoupling
of the loops, basic aspects in designing a control
system for overall plant.
 Basic aspects in designing computer control
systems and on-line optimization.
10
 Uvod, namenska funkcija in optimizacijski
kriteriji v procesnih industrijah.
 Diskretno in zvezno optimiranje: mešanoceloštevilsko linearno programiranje (MILP) in
algoritem vejanja in omejevanja, mešanoceloštevilsko nelinearno programiranje
(MINLP) in algoritem zunanje poenostavitve.
 Optimalno načrtovanje/sinteza toplotno
integriranih omrežij toplotnih prenosnikov s
sekvenčnim in simultanim pristopom.
 Optimiranje procesnih shem: SQP – zaporedno
kvadratično programiranje, optimiranje s
procesnimi simulatorji, optimiranje z
enačbnimi sistemi.
 Načrtovanje in optimiranje saržnih procesov.
Računalniške vaje:
dinamične simulacije in optimiranje.
Process optimization and integration:
 Introduction, objective function and
optimization criteria in process industries.
 Discrete and continuous optimization: mixedinteger linear programming (MILP) and branchand-bound algorithm, mixed-integer nonlinear
programming (MINLP) and outer-approximation
algorithm.
 Optimal design/synthesis of heat integrated
heat exchanger networks with sequential and
simultaneous approach.
 Process flowsheet optimization: SQP –
successive quadratic programming, optimization
with process simulators, and optimization with
equation oriented systems.
 Design and optimization of batch processes.
Computer room:
dynamic simulation and optimization.
Temeljni literatura in viri / Textbooks:
 Zdravko Kravanja: Dinamika procesov, Zapiski predavanj. Zbrano gradivo. Univerza v Mariboru,
Fakulteta za kemijo in kemijsko tehnologijo, Maribor, 2009.
 Zdravko Kravanja in Zorka Novak Pintarič: Optimiranje procesov, Zapiski predavanj. Zbrano gradivo.
Univerza v Mariboru, Fakulteta za kemijo in kemijsko tehnologijo, Maribor, 2006.
Dodatna priporočena literatura:
 Seborg, D. E., T. F. Edgar in D. A. Mellichamp, Process Dynamics and Control (2nd ed.), John Wiley &
Sons, New York, 2004.
 Ravidran A., K. M. Ragsdell in G. V. Reklaitis, Engineering Optimization, Methods and Application (2nd
ed.), John Wiley and Sons, New York, 2006.
 Biegler L. T., I. E.Grossmann and A. W.Westerberg, Systematic Methods of Chemical Process Design,
Prentice Hall, New Jersey, 1999.
 Stephanopoulos G., Chemical Process Control: An Introduction to Theory and Practice, Englewood
Cliffs, New Jersey, 1984.
Cilji in kompetence:
Podati koncept dinamičnega modeliranja in
regulacije (bio)kemijskih procesnih enot in obratov
in spoznati diskretno-kontinuirno optimiranje oz.
sintezo procesov.
Objectives and competences:
The main is to give concept of dynamic modeling
and control of process units and (bio)chemical
plants, and to present knowledge of discretecontinuous process optimization and synthesis.
Predvideni študijski rezultati:
Znanje in razumevanje:
 obvladovanje modeliranja, dinamike, regulacije
in vodenja (bio)kemijskih procesov,
 obvladovanje teorije in aplikacij
matematičnega programiranja pri načrtovanju,
planiranju in obratovanju (bio)kemijskih
procesov.
Intended learning outcomes:
Knowledge and Understanding:
 to have knowledge of modeling, dynamics and
control of (bio)chemical processes,
 to understand theory and have knowledge of
some practical applications of mathematical
programming in designing, planning and
operating (bio)chemical processes.
Prenesljive/ključne spretnosti in drugi atributi:
Imeti razumevanje o vplivu regulacijskih in
optimizacijskih rešitev na varno, okolju prijazno in
Transferable/Key Skills and other attributes:
To have an understanding of the impact of control
and optimization solutions on safe, environmentally
11
ekonomsko učinkovito delovanje kemijskih in
biokemijskih procesov.
benign and economically effective operation of
chemical and biochemical processes.
Metode poučevanja in učenja:
Learning and teaching methods:
Predavanja, seminar, laboratorijske in računalniške Lectures, seminar work, laboratory and computer
vaje, samostojno delo študenta.
practice, self-learning.
Delež (v %) /
Načini ocenjevanja:
Weight (in %)
Assessment:
Izpit je opravljen, če so pozitivno
Student has to pass successfully the
opravljene vse naslednje obveznosti:
following obligations:


teoretični del izpita
računski del izpita
30
70
Računski del izpita je mogoče nadomestiti z
dvema računskima testoma. Teoretični del
izpita je mogoče nadomestiti z dvema testoma
teorije. Teoretični in računski del izpita/testa se
izvajata sočasno.


Theoretical part of exam
Calculus part of exam
Calculus part of the exam can be replaced by two
calculus tests. Theoretical part of the exam can
be replaced by two theoretical tests.
Theory and calculus parts of the exam or test are
performed simultaneously.
Reference nosilca / Lecturer’s references:
AHMETOVIĆ, Elvis, KRAVANJA, Zdravko. Simultaneous optimization of heat-integrated water networks involving
process-to-process streams for heat integration. Applied thermal engineering, ISSN 1359-4311. [Print ed.], Jan.
2014, vol. 62, iss. 1, str. 302-217, doi: 10.1016/j.applthermaleng.2013.06.010.
NEMET, Andreja, KLEMEŠ, Jiri, KRAVANJA, Zdravko. Designing a Total Site for an entire lifetime under fluctuating
utility prices. Computers & chemical engineering, ISSN 0098-1354. [Print ed.], Available online 18 July 2014, vol. ,
str. 1-24, doi: 10.1016/j.compchemeng.2014.07.004.
ČUČEK, Lidija, MARTÍN, Mariano, GROSSMANN, Ignacio E., KRAVANJA, Zdravko. Multi-period synthesis of
optimally-integrated biomass and bioenergy supply network. Computers & chemical engineering, ISSN 0098-1354.
[Print ed.], 4 Jul. 2014, vol. 66, str. 57-70, doi: 10.1016/j.compchemeng.2014.02.020.
KRAVANJA, Zdravko, ČUČEK, Lidija. Multi-objective optimisation for generating sustainable solutions considering
total effects on the environment. V: DUIĆ, Neven (ur.). Sustainable development of energy, water and environment
systems, (Applied Energy, ISSN 0306-2619, Vol. 101, (2012)). Oxford: Elsevier, cop. 2012, vol. 101, str. 67-80, doi:
10.1016/j.apenergy.2012.04.025.
ČUČEK, Lidija, KLEMEŠ, Jiri, KRAVANJA, Zdravko. A Review of Footprint analysis tools for monitoring impacts on
sustainability. Journal of cleaner production, ISSN 0959-6526. [Print ed.], Oct. 2012, vol. 34, str. 9-20, doi:
10.1016/j.jclepro.2012.02.036.
12
Razvoj produktov in procesov
Predmet:
Course title:
UČNI NAČRT PREDMETA / COURSE SYLLABUS
Razvoj produktov in procesov
Product and Process Development
Študijski program in stopnja
Study programme and level
Kemijska tehnika / 2. stopnja
Chemical Engineering / 2nd level
Študijska smer
Study field
Letnik
Academic year
1.
Vrsta predmeta / Course type:
Semester
Semester
letni
Spring
Obvezni / Obligatory
Univerzitetna koda predmeta / University course code:
Predavanja
Lectures
30
Seminar
Seminar
Nosilec predmeta / Lecturer:
Jeziki:
Languages:
Sem. vaje
Tutorial
15
Lab. vaje
Labor work
Teren. vaje
Field work
Samost. delo
Individ. work
135
ECTS
6
Zorka Novak Pintarič
Predavanja / Lecture: slovenski / Slovene
Vaje / Tutorial: slovenski / Slovene
Pogoji za vključitev v delo oz. za opravljanje
študijskih obveznosti:
Pogojev ni.
Prerequisites:
Vsebina:
- Uporaba matematike v tehniški ekonomiki.
- Stopnje v sistematičnem razvoju produktov in
procesov.
- Dimenzioniranje in investicijsko vrednotenje
procesne opreme. Vpliv inflacije na ceno.
- Ocenjevanje investicije osnovnih sredstev.
- Amortizacija.
- Prihodki in obratovalni stroški.
- Ocenjevanje investicije obratnih sredstev.
- Statični in dinamični kriteriji ekonomske
upravičenosti.
- Analiza denarnih tokov.
- Izbor med alternativami.
- Inkrementalna ekonomska analiza.
- Negotovost in tveganje pri ekonomski analizi.
Content (Syllabus outline):
- Mathematics in engineering economics.
- Steps in systematic product and process
development.
- Equipment sizing and costing. Effect of inflation.
- Fixed capital cost estimation.
- Depreciation.
- Annual sales revenues and production costs.
- Working capital and total capital investment.
- Static and dynamic profitability measures.
- Cash flow analysis.
- Selection between alternatives.
- Incremental analysis.
- Uncertainty and risk in economic evaluation.
Vaje:
- Priprava projektne dokumentacije.
- Ocenjevanje investicije z računalniškimi
programi in literaturnimi viri.
None.
Labor work:
- Preparation of project documentation.
13
- Izdelava študije možnosti za izbrani proces.
- Analize občutljivosti.
- Študija primera: Načrtovanje kemijskega
produkta
- Evaluation of capital cost by applying advanced
software tools and literature.
- Feasibility study of the selected production plant.
- Sensitivity analyses.
- Case study: Design of chemical product
Temeljni literatura in viri / Textbooks:
 Z. Novak Pintarič: Razvoj procesov v kemijski industriji, zbrano gradivo. Univerza v Mariboru, Fakulteta
za kemijo in kemijsko tehnologijo, Maribor, 2014.
http://www.fkkt.um.si/egradiva/fajli/Razvoj_procesov.pdf
 Z. Novak Pintarič: Razvoj produktov in procesov: zbirka nalog za računske vaje. Maribor: Fakulteta za
kemijo in kemijsko tehnologijo, 2014. https://estudij.um.si/mod/resource/view.php?id=38331,
http://dkum.uni-mb.si/IzpisGradiva.php?id=44464. [COBISS.SI-ID 17584150]
Dodatna priporočena literatura:
 R. A. Brealey, S. C. Myers, A. J. Marcus: Fundamentals of Corporate Finance. Sixth Edition, McGraw Hill,
New York, 2009.
 W. D. Seider, J. D. Seader, D. R. Lewin: Product and process design principles: synthesis, analysis, and
evaluation. Second Edition, Wiley, New York, 2004.
 A. Chauvel, G. Fournier, C. Raimbault: Manual of Process Economic Evaluation. Editions Technip, Paris,
2003.
Cilji in kompetence:
Cilji tega predmeta so:
- integracija znanj, ki jih dobijo študentje
predhodno pri specifičnih tehniških predmetih,
- obvladovanje stopenj v razvoju kemijskih in
biokemijskih produktov in procesov,
- osvojitev metodologije za pripravo študije
možnosti in ocenjevanje ekonomske
upravičenosti.
Objectives and competences:
The objectives of this course are:
- integration of students' knowledge and skills
acquainted by specific engineering subjects,
- to acquire the steps in integral approach for
development of chemical and biochemical
products and processes,
- to acquire the methodology for performing
feasibility studies with economic evaluation.
Predvideni študijski rezultati:
Znanje in razumevanje:
- poznavanje razvoja tehnološkega projekta od
ideje do realizacije,
- obvladovanje koncepta tehnološko-poslovnega
odločitvenega procesa,
- poznavanje pristopov in metod za pripravo študij
možnosti, t.j. oceno investicije, obratovalnih
stroškov, amortizacije in drugih odhodkov,
- poznavanje kriterijev za oceno uspešnosti
posameznega projekta,
- sposobnost izbire med alternativnimi projekti.
Prenesljive/ključne spretnosti in drugi atributi:
- kreiranje idej in inovativnih tehnoloških rešitev,
- uporabo strokovnih in znanstvenih informacijskih
virov,
- določevanje prioritet pri izvajanju projektov,
- časovno planiranje in vodenje tehnoloških
projektov, sprejemanje odločitev,
- timsko delo pri razvoju tehnoloških projektov od
ideje do realizacije,
- izdelavo projektnih poročil in ustno
komuniciranje o problematiki v globalnem tržnem
Intended learning outcomes:
Knowledge and Understanding:
- integrate and use specific engineering
knowledges by executing technical projects from
the idea to realization,
- understand the basic concepts of technologicalbussines decision making process,
- prepare feasibility studies, evaluate investment
cost, revenues, depreciation and operating costs,
- calculate various profitability measures for
evaluation of single project,
- select between alternative projects.
Transferable/Key Skills and other attributes:
The student is able to:
- create ideas and solve problems inventively,
- use technical and scientific information sources,
- determine priorities by executing the projects,
- plan and manage technological projects,
- team work for project development from idea to
realization,
- write reports,
- present material oraly.
14
okolju.
Metode poučevanja in učenja:
Learning and teaching methods:
- predavanja,
- lectures,
- računski in študijski primeri, domače naloge,
- calculating examples, case studies, homeworks,
- uporaba računalniških programov za ekonomske
- use of computer tools in economic analyses
analize,
- active team work for peparation of project with
- aktivno skupinsko delo za izdelavo projektne
feasibility study.
naloge s študijo možnosti.
Delež (v %) /
Načini ocenjevanja:
Weight (in %)
Assessment:
Izpit je opravljen, če so pozitivno
Student has to pass successfully the
opravljene vse naslednje obveznosti:
following obligations:
- pisni računski izpit
- izpit teorije
- projektno poročilo
60
20
20
Izpit teorije se lahko izvaja ustno ali pisno.
- written examination (calculus)
- theory examination
- written report on project work
Theory examination can be performed orally or
in writing.
Reference nosilca / Lecturer’s references:
NOVAK-PINTARIČ, Zorka, IBRIĆ, Nidret, AHMETOVIĆ, Elvis, GROSSMANN, Ignacio E., KRAVANJA, Zdravko. Designing
optimal water networks for the appropriate economic criteria. V: 21st International Congress of Chemical and
Process Engineering CHISA 2014 [and] 17th Conference PRES 2014, 23 - 27 August 2014, Praha, Czech Republic.
Praha: [s. n.], 2014, 1 str. [COBISS.SI-ID 18099478]
KASAŠ, Mihael, KRAVANJA, Zdravko, NOVAK-PINTARIČ, Zorka. Achieving profitably, operationally, and
environmentally compromise flow-sheet designs by a single-criterion optimization. AIChE journal, ISSN 0001-1541.
[Print ed.], July 2012, vol. 58, iss. 7, str. 2131-2141, doi: 10.1002/aic.12747. [COBISS.SI-ID 15215126]
KASAŠ, Mihael, KRAVANJA, Zdravko, NOVAK-PINTARIČ, Zorka. Suitable modeling for process flow sheet
optimization using the correct economic criterion. Industrial & engineering chemistry research, ISSN 0888-5885.
[Print ed.], 2011, vol. 50, iss. 6, str. 3356-3370, doi: 10.1021/ie101485z. [COBISS.SI-ID 14805526]
NOVAK-PINTARIČ, Zorka. Navodila za uporabo programa Aspen Process Economic Analyzer : za vaje pri predmetu
Razvoj produktov in procesov. Maribor: Fakulteta za kemijo in kemijsko tehnologijo, 2014. [8] f., ilustr.
https://estudij.um.si/mod/resource/view.php?id=38332,http://dkum.uni-mb.si/IzpisGradiva.php?id=44462.
[COBISS.SI-ID 17584406]
NOVAK-PINTARIČ, Zorka. Razvoj produktov in procesov: zbirka nalog za računske vaje. Maribor: Fakulteta za kemijo
in kemijsko tehnologijo, 2014. [14] f., ilustr. https://estudij.um.si/mod/resource/view.php?id=38331,
http://dkum.uni-mb.si/IzpisGradiva.php?id=44464. [COBISS.SI-ID 17584150]
15
Procesne naprave
Predmet:
Course title:
UČNI NAČRT PREDMETA / COURSE SYLLABUS
Procesne naprave
Process Equipment
Študijska smer
Study field
Študijski program in stopnja
Study programme and level
Letnik
Academic year
Semester
Semester
1.
letni
Spring
Kemijska tehnika / 2. stopnja
Chemical Engineering / 2nd level
Vrsta predmeta / Course type:
Obvezni / Obligatory
Univerzitetna koda predmeta / University course code:
Predavanja
Lectures
Seminar
Seminar
Sem. vaje
Tutorial
30
Nosilec predmeta / Lecturer:
Jeziki /
Languages:
Lab. vaje
Laboratory
work
30
Teren. vaje
Field work
Samost. delo
Individ. work
ECTS
120
6
Darko Goričanec
Predavanja / Lectures: slovenski / Slovene
Vaje / Tutorial: slovenski / Slovene
Pogoji za vključitev v delo oz. za opravljanje
študijskih obveznosti:
Osnovno znanje mehanike fluidov in prenosa
toplote.
Prerequisits:
Vsebina:
Content (Syllabus outline):
 Naprave za homogenizacijo tekočin - mešala in
mešalne posode.
 Naprave za prenos tekočin: cevovodi, ventili,
kompenzatorji, črpalke. Projekt pretočnega
sistema za nevtralizacijo odpadnih vod.
 Naprave za prenos plinov: ventilatorji in
kompresorji. Projekt prezračevanja digestorija
in kompresorske postaje.
 Naprave za ločevanje tekočin – kolone.
 Vakuumski sistemi: pridobivanje vakuuma,
nepropustnost, črpalke, ejektorji
 Toplotne črpalke.
 Naprave za centrifugiranje, filtracijo in
sedimentacijo.
 Device for fluid homogenization – mixers and
mixing vessels.
 Fluid transfer devices: pipes, valves,
compensators, pumps. Project of fluid flow
system for neutralising waste water.
 Gas transfer devices: ventilators and compressors
Project for ventilation of digestories and
compressor station.
 Devices for fluid separation - columns
 Vacuum systems: creating of vacuums,
impermeability, pumps and ejectors
 Heat pumps
 Devices for centrifugation, filtration and
sedimentation.
Basic knowledge of fluid mechanics and heat
transfer.
16
Projektno delo temelji na primerih, ki se navezujejo
na predmet in krajši projektni nalogi.
Project work is based on the chosen topic, regarding
the theme of the subject and short process design
project formulation.
Temeljni literatura in viri / Readings:
 Goričanec, Darko, Krope, Jurij. Procesne naprave: zbrano gradivo pri predmetu Procesne naprave.
Univerza v Mariboru, Fakulteta za kemijo in kemijsko tehnologijo, 2006.
http://www.fkkt.um.si/egradiva/fajli/Procesne_naprave.pdf.
Dodatna priporočena literatura:
 Charles E. Thomas: Process Technology Equipment and Systems, Cengage Learning; 4 edition, 2014.
 CAPT: Process Technology Equipment, Prentice Hall; 1 edition, 2009.
Cilji in kompetence:
 Razviti sposobnost študentov za samostojno in
kreativno reševanje inženirskih problemov.
 Razumevanje delovanja procesnih sistemov.
 Načrtovanje učinkovitejših procesnih sistemov.
Objectives and competences:
 To further develop student's capabilities of
independent thinking and creative solution of
engineering problems.
 Understanding the functioning of process
systems.
 Designing more efficient process systems.
Predvideni študijski rezultati:
Znanje in razumevanje:
 Razumevanje povezave različnih znanj in
postopkov ter pomena uporabe strokovne
literature za učinkovito reševanje inženirskih
problemov.
Intended learning outcomes:
Knowledge and Understanding:
 Understanding of relationships between
different skills and procedures and importance
of professional literature for efficient solutions
of process problems.
Prenesljive/ključne spretnosti in drugi atributi:
 Kombinirana uporaba različnih naprednih znanj
za reševanje inženirskih problemov
 Z mentorskim reševanjem konkretnih primerov
se oblikuje študentova kreativnost in logično
razmišljanje, potrebno za uspešno delo v praksi.
Transferable/Key Skills and other attributes:
 Combined use of different fundamental skills for
solution of engineering problems.
 Solving concrete examples under supervision
and hence developing student’s creativity and
logical thinking, needed for successful work in
practice.
Metode poučevanja in učenja:
Predavanja: študent spozna teoretične vsebine
predmeta.
Laboratorijske vaje: študent utrdi teoretično znanje
in spozna aplikativne možnosti reševanja primerov
iz prakse, študent izdela krajšo študijo oz. projekt, ki
se navezuje na tematiko predmeta.
Learning and teaching methods:
Lectures: the student gets acquainted with
theoretical content of the subject.
Laboratory work: the student upgrades the
theoretical knowledge with practical experience,
conducting a short study or project regarding the
thematic of the subject.
17
Načini ocenjevanja:
Izpit je opravljen, če so pozitivno opravljene
vse naslednje obveznosti:
 seminarska naloga
 teoretični del izpita
 računski del izpita
Delež (v %) /
Weight (in %)
20
30
50
Teoretični in računski del tvorita celoto in se
preverjata hkrati.
Assessment:
Student has to pass successfully the
following obligations:
 seminar
 theoretical part of the exam
 calculation part of the exam
The theoretical and the calculus part of the exam
are performed simultaneously.
Reference nosilca / Lecturer’s references:
GORIČANEC, Darko, POZEB, Viljem, TOMŠIČ, Ladislav, TROP, Peter. Exploitation of the waste-heat from hydro
power plants. Energy, ISSN 0360-5442. [Print ed.], Available online 22 July 2014, str. 1-6.
ANICIC, B., TROP, Peter, GORIČANEC, Darko. Comparison between two methods of methanol production from
carbon dioxide. Energy, ISSN 0360-5442. [Print ed.], 2014, 77, str. 279-289, doi: 10.1016/j.energy.2014.09.069.
[COBISS.SI-ID 80681729].
DOBERŠEK, Danijela, GORIČANEC, Darko, KROPE, Jurij. Dryers for sewage sludge dehydration. International journal
of energy and environment, 2012, vol. 6, iss. 6, str. 588-596.
http://www.naun.org/multimedia/NAUN/energyenvironment/16-691.pdf. [COBISS.SI-ID 16535062].
KULČAR, Bojan, GORIČANEC, Darko, KROPE, Jurij. Economy of replacing a refrigerant in a cooling system for
preparing chilled water = Remplacement du frigorigene dans un systeme utilisé pour préparer de l'eau glacée :
impact financier. International journal of refrigeration, ISSN 0140-7007. [Print ed.], Aug. 2010, vol. 33, iss. 5, str.
989-994.
ŽLAK, Janez, AGREŽ, Marko, DOBERŠEK, Danijela, GORIČANEC, Darko, KROPE, Jurij. Rentability of rotary heat
regenerator use in ventilating systems = Rentabilnost upotrebe regeneratora topline u ventilacijskom sustavu.
Strojarstvo, ISSN 0562-1887, 2010, vol. 52, no. 6, str. 665-671. [COBISS.SI-ID 15454486].
18
Bioseparacijska tehnika in biokataliza
Predmet:
Course title:
UČNI NAČRT PREDMETA / COURSE SYLLABUS
Bioseparacijska tehnika in biokataliza
Bioseparation Processes and Biocatalysis
Študijski program in stopnja
Study programme and level
Kemijska tehnika / 2. stopnja
Chemical Engineering / 2nd level
Študijska smer
Study field
Letnik
Academic year
1.
Vrsta predmeta / Course type:
Semester
Semester
letni
Spring
Obvezni / Obligatory
Univerzitetna koda predmeta / University course code:
Predavanja
Lectures
45
Seminar
Seminar
Nosilec predmeta / Lecturer:
Jeziki /
Languages:
Sem. vaje
Tutorial
Lab. vaje
Labor work
30
Teren. vaje
Field work
Samost. delo
Individ. work
105
ECTS
6
Željko Knez, Maja Leitgeb
Predavanja / Lecture: slovenski / Slovene
Vaje / Tutorial: slovenski / Slovene
Pogoji za vključitev v delo oz. za opravljanje
študijskih obveznosti:
Potrebno je znanje separacijske tehnike ter
osnovno znanje biokemije, biokemijske tehnike in
biotehnologije.
Prerequisites:
Vsebina:
- Bioseparacijska tehnika:
Separacija (flokulacija in flotacija, filtracija,
centrifugiranje), koncentriranje (ekstrakcija,
membranski procesi), sušenje.
- Biokataliza:
kinetika biokataliziranih reakcij, določevanje
kinetičnih parametrov, imobilizacija
biokatalizatrojev, modeliranje biokataliziranih
reakcij.
Content (Syllabus outline):
- Bioseparation processes:
Separation (flocculation and flotation, filtration,
centrifugation), concentration (extraction,
membrane processes), drying.
- Biocatalysis:
kinetic of biocatalyzed reactions, determination of
kinetic parameters,immobilization of biocatalysts,
modelling of biocatalyzed reactions.
Knowledge of separation processes and basic
knowledge of biochemistry, biochemical
engineering and biotechnooogy is needed.
Project will be based on experimental work from
the field of biocatalytic processes, integrated with
bioseparation processes.
Projektno delo bo potekalo na osnovi
laboratorijskih eksperimentov s področja
biokatalitičnih procesov, kjer bodo istočasno
zajeti tudi bioseparacijski procesi.
19
Temeljni literatura in viri / Textbooks:
 B. Elvers, S. Hawkins, W. E Russey: Ullmann's encyclopedia of industrial chemistry, izbrana poglavja,
Weinheim, Cambridge: Wiley-VCH, 2003.
Dodatna priporočena literatura:
 M. C. Flickinger, Upstream and Downstream Industrial Biotechnology, 3V Bundle, Wiley, ISBN: 978-1118-13125-1, 2014.
 M. C. Flickinger, Encyclopedia of Industrial Biotechnology, Bioprocess, Bioseparation, and Cell
Technology , 7 Volume Set, Wiley, ISBN: 978-0-471-79930-6, 2010.
 A. Illanes, L. Wilson, C. Vera, Problem Solving in Enzyme Biocatalysis, Wiley, ISBN: 978-1-118-34171-1,
2013.
 J. A. Tao, R. J. Kazlauskas, Biocatalysis for Green Chemistry and Chemical Process Development, Wiley,
ISBN: 978-0-470-43778-0, 2011.
Cilji in kompetence:
Na osnovi projektnega dela spoznati
bioseparacijske metode ter poglobljena znanja iz
biokatalize.
Objectives and competences:
On the basis of project work the sudets will get the
knowledge about bioseparation processes, as well
as advanced knowledge of biocatalysis.
Predvideni študijski rezultati:
Znanje in razumevanje:
Zmožnost načrtovanja biokatalitskega sistema;
uporaba ustreznih bioseparacijskih metod v
povezavi z biokataliziranim sistemom.
Intended learning outcomes:
Knowledge and Understanding:
Design of biocatalytic systems; application of
bioseparation processes for a defined biocatalytic
system.
Prenesljive/ključne spretnosti in drugi atributi:
Vsebina predmeta je povezana z ostalimi predmeti
na smeri Biokemijska tehnika in podaja znanja, ki
so nujno potrebna za razumevanje vsebin, ki so
zajete pri predmetih Industrijska mikrobiologija in
Bioreakcijska tehnika.
Transferable/Key Skills and other attributes:
The subject is strongly connected to the other
subjects on the direction Biochemical engineering
and gives the knowledge which is necessarry for
understanding other subjects, such as Industrial
microbiology and Bioreaction engineering.
Metode poučevanja in učenja:
Predavanja v učilnici, ki je opremljena z avdiovizualnimi pripomočki.
Learning and teaching methods:
Lectures in lecture room, equipped with audio-visual
equipment
Individualna priprava projektne naloge s
predstavitvijo in diskusijo.
Individual preparation of project work with the
presentation with discussion.
Načini ocenjevanja:
Izpit je opravljen, če so pozitivno
opravljene vse naslednje obveznosti:
- ustni izpit
- projektno poročilo
- predstavitev projekta
Delež (v %) /
Weight (in %)
50
25
25
20
Assessment:
Student has to pass successfully the
following obligations:
- oral examination
- project written report
- project oral presentation
Reference nosilca / Lecturer’s references:
KNEZ, Željko, KAVČIČ, Sabina, GUBICZA, László, BÉLAFI-BAKÓ, Katalin, NÉMETH, Gergely, PRIMOŽIČ, Mateja,
LEITGEB, Maja. Lipase-catalyzed esterification of lactic acid in supercritical carbon dioxide. The Journal of
supercritical fluids, ISSN 0896-8446. 2012, 66, 192-197, doi: 10.1016/j.supflu.2011.11. [COBISS.SI-ID 15598102]
ŠULEK, Franja, PÉREZ FERNÁNDEZ, Daniel, KNEZ, Željko, LEITGEB, Maja, SHELDON, Roger A. Immobilization of
horseradish peroxidase as crosslinked enzyme aggregates (CLEAs). Process biochemistry, ISSN 1359-5113, 2011, 46
(3), 765-769, doi: 10.1016/j.procbio.2010.12.001. [COBISS.SI-ID 14712598]
CSANÁDI, Zsófia, BÉLAFI-BAKÓ, Katalin, SZENTGYÖRGYI, Eszter, GUBICZA, László, KNEZ, Željko, LEITGEB, Maja.
Enzymatic esterification of glycerol and stearic acid in non-conventional media. Acta chimica slovenica, ISSN 13180207. 2010, 57 (1), 244-249. COBISS.SI-ID 14029590]
ŠULEK, Franja, KNEZ, Željko, LEITGEB, Maja. Immobilization of cholesterol oxidase to finely dispersed silica-coated
maghemite nanoparticles based magnetic fluid. Applied Surface Science, ISSN 0169-4332. 2010, 256 (14), 45964600. [COBISS.SI-ID 14055446]
THOREY, Paul, KNEZ, Željko, LEITGEB, Maja. Alcohol dehydrogenase in non-aqueous media using high-pressure
technologies : reaction set-up and deactivation determination. Journal of chemical technology and biotechnology,
ISSN 0268-2575. 2010, 85, 1011-1016. [COBISS.SI-ID 14291222]
21
Bioreakcijska tehnika
UČNI NAČRT PREDMETA / COURSE SYLLABUS
Bioreakcijska tehnika
Bioreaction Engineering
Predmet:
Course title:
Študijski program in stopnja
Study programme and level
Kemijska tehnika / 2. stopnja
Chemical Engineering / 2nd level
Študijska smer
Study field
Letnik
Academic year
1.
Vrsta predmeta / Course type:
Semester
Semester
letni
Summer
Obvezni / Obligatory
Univerzitetna koda predmeta / University course code:
Predavanja
Lectures
30
Seminar
Seminar
Nosilec predmeta / Lecturer:
Jeziki / Languages:
Sem. vaje
Tutorial
Lab. vaje
Labor work
30
Teren. vaje
Field work
amost. delo
Individ. work
120
ECTS
6
Andreja Goršek
Predavanja / Lecture: slovenski / Slovene
Vaje / Tutorial: slovenski / Slovene
Pogoji za vključitev v delo oz. za opravljanje
študijskih obveznosti:
Potrebna so osnovna znanja termodinamike,
biokemije, biokemijske in reakcijske tehnike.
Prerequisites:
Vsebina:
Predavanja:
Uvodni pojmi.
Bioreakcijska kinetika (encimska in mikrobiološka).
Tipi bioreaktorjev: osnovni (mešalni, kolonski, z
dvigovanjem zraka) in posebni tipi.
Tehnološke zahteve pri načrtovanju bioreaktorjev
(mešanje, snovni in toplotni prenos).
Modeliranje biokemijskih reakcijskih sistemov
(šaržni, pretočni, kaskada pretočnih bioreaktorjev,
šaržni z dotokom substrata).
Ekonomika bioprocesov.
Content (Syllabus outline):
Lectures:
Fundamentals.
Bioreaction kinetics (enzymatic and microbial)
Type of bioreactors: basic (mixed, bubble column,
airlift) and special types.
Technological requirements in bioreactor design
(mixing, mass transfer, heat transfer).
Modeling of biochemical reaction systems (batch,
continuous, continuous in series, fed-batch).
Bioprocess economics
Laboratorijske vaje:
Poudarek je na načrtovanju bioreaktorjev:
 aerobni reaktor
 anaerobni reaktor
 aeracijska enota
Laboratorial exercises:
The main emphasis is focused on bioreactor design:
 aerobic reactor
 anaerobic reactor
 aeration unit
Basic knowledge about thermodynamics,
biochemistry and reaction engineering is required.
22
Projektno delo:
Študentje izberejo bioproces, ga analizirajo in
pripravijo predstavitev.
Project work:
Student choose a bioprocess, perform the analysis
and prepare public presentation.
Temeljni literatura in viri / Textbooks:
 A. Goršek. Bioreakcijska tehnika: zbrano gradivo, http://www.fkkt.um.si/egradiva/fajli/brt.pdf, 2007.
 M. Tramšek, A. Goršek, Bioreakcijska tehnika: navodila za laboratorijske vaje, UM FKKT, 2005.
 Levenspiel, Chemical Reaction Engineering, John Wiley & Sons, New York, 1999.
Dodatna priporočena literatura:
 P. M. Doran, Bioprocess Engineering Principles, Elsevier Ltd., London, 2004.
 I. J. Dunnn, E. Heinzle, J. Ingham, J.E. Prenosil, Biological reaction Engineering, Dinamic Modelling
Fundamentals with Simulation Examples, Wiley-VCH, Weinheim, 2003.
Cilji in kompetence:
Vključevanje principov kemijske reakcijske tehnike
v biokemijske sisteme. Predstavitev različnih tipov,
konfiguracij in aplikacij bioreaktorjev ter
fermentorjev. Seznanitev z osnovnimi in
kompleksnejšimi biokinetičnimi modeli ter njihovo
uporabo pri modeliranju šaržnih, semikontinuiranih in kontinuiranih bioreaktorskih
sistemov.
Objectives and competences:
Incorporating the principles of chemical reaction
engineering in biochemical systems.
Presenting the different types, configurations and
applications of bioreactors and fermentors.
Introducing the basic and complex biokinetic models
and their application in modeling of batch, semicontinuous and continuous bioreactor systems.
Predvideni študijski rezultati:
Znanje in razumevanje:
Razumevanje principov encimskih in mikrobnih
reakcij. Poznavanje stehiometrije, in kinetike
biokemijskih reakcij. Poznavanje snovnih bilanc
bioprocesov v dinamičnem ter stacinarnem stanju.
Dinamično modeliranje različnih tipov
bioreaktorjev.
Intended learning outcomes:
Knowledge and Understanding:
Understanding the principles of enzymatic and
microbial reactions. Knowledge the stehiometry and
kinetics of biochemical reactions. Knowledge of the
unsteady and steady-state material balances of
bioprocesses. Dynamic modeling of different
bioreactor types.
Prenesljive/ključne spretnosti in drugi atributi:
Modeliranje mikrobiološke rasti in encimskih
reakcij z ali brez inhibicije. Izvajanje osnovnih
tehnoloških izračunov za načrtovanje
bioreaktorjev, upoštevajoč velikost, mešalni režim
in kapaciteto snovnega prenosa.
Transferable/Key Skills and other attributes:
Modeling of microbial growth and enzymatic
reactions with or without inhibition.
Executing of basic reaction engineering calculations
for bioreactors design including size, stirrer regime
and mass transfer capacity.
Metode poučevanja in učenja:
 Predavanja, obogatena z računskimi primeri,
multimedijskim materialom (simulacije, slike,
diagrami) in primeri iz industrije.
 Pomoč pri reševanju računskih nalog.
 Individualno delo – priprava projekta in javna
predstavitev.
 Pomoč pri iskanju biokemijskih informacij in
podatkov na spletu ter drugih elektronskih virih.
 Pisno reševanje nalog.
Learning and teaching methods:
 Lectures, enriched with numerical problems,
multimedia material (simulations, pictures,
diagrams) and case studies from industry
 Helping students at solving numerical problems.
 Individual work – project preparation and public
presentation.
 Helping students with biochemical data searching
on internet and other electronic sources.
 Written test on problem solving skills.
23
Načini ocenjevanja:
Izpit je opravljen, če so pozitivno
opravljene vse naslednje obveznosti:
 pisno poročilo o laboratorijskih vajah
 projektno poročilo
 pisni izpit
Delež (v %) /
Weight (in %)
30
20
50
Assessment:
Student has to pass successfully the
following obligations:
 laboratory work written report
 project report
 written exam
Reference nosilca / Lecturer’s references:
ZAJŠEK, Katja, KOLAR, Mitja, GORŠEK, Andreja. Characterisation of the exopolysaccharide kefiran produced by
lactic acid bacteria entrapped within natural kefir grains. International journal of dairy technology, ISSN 1364-727X,
2011, vol. 64, issue 4, str. 544-548, doi: 10.1111/j.1471-0307.2011.00704.x. [COBISS.SI-ID 15278870].
ZAJŠEK, Katja, GORŠEK, Andreja. Experimental assessment of the impact of cultivation conditions on kefiran
production by the mixed microflora imbedded in kefir grains. V: 9th International Conference on Chemical and
Process Engineering, 8-11 May, 2011, Florence, Italy. PIERUCCI, Sauro (ur.). ICheaP-10, (Chemical Engineering
transactions, ISSN 1974-9791, Vol. 24). Milano: AIDIC, 2011, str. 481-486, doi: 10.3303/CET1124081. [COBISS.SI-ID
14955798].
PEČAR, Darja, SLEMNIK, Mojca, GORŠEK, Andreja. Testing the corrosion resistance of stainless steels during the
fermentation of probiotic drink. Journal of the Science of Food and Agriculture, ISSN 0022-5142, May 2011, vol. 91,
iss. 7, str. 1293-1297, doi: 10.1002/jsfa.4315. [COBISS.SI-ID 14809622].
ZAJŠEK, Katja, GORŠEK, Andreja, KOLAR, Mitja. Cultivating conditions effects on kefiran production by the mixed
culture of lactic acid bacteria imbedded within kefir grains. Food chemistry, ISSN 0308-8146. [Print ed.], Jan. 2013,
vol. 139, iss. 1-4, str. 970-977, doi: 10.1016/j.foodchem.2012.11.142. [COBISS.SI-ID 16645142].
VNUČEC, Doroteja, GORŠEK, Andreja, KUTNAR, Andreja, MIKULJAN, Marica. A new method of physical
modification of soy proteins for wood adhesives. V: International conference on wood adhesives : 9-11 october,
2013, Toronto, Ontario, Canada. [Madison]: Forest Products Society, 2014, str. 570-576, ilustr. [COBISS.SI-ID
1536529092].
24
Načrtovanje procesov - projekt
Predmet:
Course title:
UČNI NAČRT PREDMETA / COURSE SYLLABUS
Načrtovanje procesov - projekt
Process Design - Project Načrtovanje procesov - projekt
Študijski program in stopnja
Study programme and level
Kemijska tehnika / 2. stopnja
Chemical Engineering / 2nd level
Študijska smer
Study field
Kemijska tehnika
Chemical Engineering
Vrsta predmeta / Course type:
Letnik
Academic year
1.
Semester
Semester
letni
Spring
Obvezni / Obligatory
Univerzitetna koda predmeta / University course code:
Predavanja
Lectures
Seminar
Seminar
Nosilec predmeta / Lecturer:
Jeziki /
Languages:
Sem. vaje
Tutorial
45
Lab. vaje
Labor work
Teren. vaje
Field work
Samost. delo
Individ. work
135
ECTS
6
Zorka Novak Pintarič
Predavanja / Lecture:
Vaje / Tutorial: slovenski / Slovene
Pogoji za vključitev v delo oz. za opravljanje
študijskih obveznosti:
Potrebno je znanje iz termodinamike, prenosa
toplote in snovi ter osnovno znanje iz separacijske
in reakcijske tehnike.
Prerequisites:
Vsebina:
Računalniške vaje - projekt:
Izbor procesa, sinteza procesne sheme. Simulacija
procesa z rigoroznimi modeli in termodinamiko.
Termodinamska analiza, toplotna integracija,
načrtovanje omrežja toplotnih prenosnikov.
Ekonomsko in okoljsko vrednotenje procesa.
Priprava projektnega poročila. Ustna predstavitev
projekta.
Content (Syllabus outline):
Computer Exercises - project:
Selection of process, synthesis of process flow
sheet. Process simulation using rigorous models and
thermodynamics. Thermodynamic analysis, heat
integration, Heat Exchanger Network design.
Process economics and environmental evaluation.
Preparation of written project report. Oral
presentation of project.
Knowledge of thermodynamics, heat and mass
transfer and basic knowledge of separation and
reaction engineering is required.
Temeljni literatura in viri / Textbooks:
 Z. Novak Pintarič, Načrtovanje in integracija procesov, zbrano gradivo. Univerza v Mariboru, Fakulteta
za kemijo in kemijsko tehnologijo, Maribor, 2014.
 Z. Novak Pintarič, Simulacija kemijskih procesov, zbrano gradivo. Univerza v Mariboru, Fakulteta za
kemijo in kemijsko tehnologijo, Maribor, 2014.
 M. Bogataj, A. Goršek, P. Glavič, Načrtovanje procesov, Navodila za vaje, Univerza v Mariboru,
Fakulteta za kemijo in kemijsko tehnologijo, Maribor, 2005.
Dodatna priporočena literatura:
25
 R. Smith, Chemical Process Design and Integration, J. Wiley, 2005.
 J. J. Klemeš (Ed.), Handbook of Process Integration (PI), Woodhead Publishing, Cambridge, 2013.
Cilji in kompetence:
Sinteza znanj iz kemije, termodinamike, osnovnih
pojavov in operacij, varnosti in okolja, ekonomike
Objectives and competences:
Synthesis of knowledge, acquired in: chemistry,
basic phenomena, thermodynamics, unit
operations, safety, environmental protection,
economics, etc.
Predvideni študijski rezultati:
Znanje in razumevanje:
Konceptualno načrtovanje procesov, toplotna
integracija. Povezovanje pridobljenih znanj.
Razširitev znanja na kompleksne procese (več
procesnih enot).
Intended learning outcomes:
Knowledge and Understanding:
Conceptual process design, heat integration. Linking
the acquired knowledge. Knowledge extension to
complex processes (more process units).
Prenesljive/ključne spretnosti in drugi atributi:
Računalniško načrtovanje zahtevnejših celotnih
procesnih shem. Razvijanje sposobnosti za
skupinsko in projektno delo.
Transferable/key skills and other attributes:
Computer aided design and retrofit of more
complex total process systems. Abilities to work in
team. Experience in executing large projects.
Metode poučevanja in učenja:
Uporaba tujih jezikov in literature.
Skupinske računalniške vaje simuliranja,
integriranja, načrtovanja, optimiranja procesa,
ekonomskega vrednotenja investicij.
Pisanje in zagovor skupinskega projektnega
poročila.
Learning and teaching methods:
Usage of foreign languages and literature.
Team-work in process simulation, integration,
design, optimization, and economic evaluation of
the investment.
Writing and defence of the team design report.
Načini ocenjevanja:
Izpit je opravljen, če so pozitivno
opravljene vse naslednje obveznosti:
- projektno delo
- projektno poročilo
- predstavitev projekta
Delež (v %) /
Weight (in %)
10
60
30
Assessment:
Student has to pass successfully the
following obligations:
- computer exercises
- project work and report
- project presentation
Reference nosilca / Lecturer’s references:
NOVAK-PINTARIČ, Zorka, KRAVANJA, Zdravko. Suitable process modelling for proper multi-objective optimization
of process flow sheets. V: KLEMEŠ, Jiri (ur.), VARBANOV, Petar (ur.), LIEW, Peng Yen (ur.). 24th European
Symposium on Computer Aided Process Engineering : [ESCAPE-24, 15 to 18 June 2014, Budapest, Hungary],
(Computer aided chemical engineering, ISSN 1570-7946, 33). Amsterdam ... [et al.]: Elsevier, cop. 2014, str. 13881392. [COBISS.SI-ID 18172438]
KRAVANJA, Zdravko, NOVAK-PINTARIČ, Zorka, SIMONIČ, Marjana, ŠKOF, Gorazd. Optimizacija obstoječe in
načrtovanje nove naprave za čiščenja odpadnih oljnih emulzij : zaključno poročilo projekta. Maribor: Fakulteta za
kemijo in kemijsko tehnologijo, Laboratorij za procesno sistemsko tehniko in trajnostni razvoj, 2013. 53 str., ilustr.
[COBISS.SI-ID 17120534]
TOKOS, Hella, NOVAK-PINTARIČ, Zorka, GLAVIČ, Peter. Energy saving opportunities in heat integrated beverage
plant retrofit. Applied thermal engineering, ISSN 1359-4311. [Print ed.], Jan. 2010, vol. 30, no. 1, str. 36-44, doi:
10.1016/j.applthermaleng.2009.03.008. [COBISS.SI-ID 13122838]
NOVAK-PINTARIČ, Zorka. Načrtovanje in integracija procesov : zbrano gradivo za predmet Načrtovanje procesov na
bolonjskem magistrskem programu Kemijska tehnika. Maribor: Fakulteta za kemijo in kemijsko tehnologijo, 2014.
[145] f., ilustr. https://estudij.um.si/mod/resource/view.php?id=21344, http://dkum.unimb.si/IzpisGradiva.php?id=44461. [COBISS.SI-ID 17583638]
26
NOVAK-PINTARIČ, Zorka. Simulacija kemijskih procesov : zbrano gradivo za vaje pri predmetu Načrtovanje
procesov na bolonjskem magistrskem programu Kemijska tehnika. Maribor: Fakulteta za kemijo in kemijsko
tehnologijo, 2014. [37] f., ilustr. https://estudij.um.si/mod/resource/view.php?id=21375, http://dkum.unimb.si/IzpisGradiva.php?id=44466. [COBISS.SI-ID 17583894]
27
Industrijska mikrobiologija
Predmet:
Course title:
UČNI NAČRT PREDMETA / COURSE SYLLABUS
Industrijska mikrobiologija
Industrial Microbiology
Študijski program in stopnja
Study programme and level
Kemijska tehnika / 2. stopnja
Chemical Engineering / 2nd level
Študijska smer
Study field
Biokemijska tehnika
Biochemical Engineering
Vrsta predmeta / Course type
Letnik
Academic year
1.
Semester
Semester
letni
Summer
Obvezni / Obligatory
Univerzitetna koda predmeta / University course code:
Predavanja
Lectures
30
Seminar
Seminar
Nosilec predmeta / Lecturer:
Jeziki /
Languages:
Sem. vaje
Tutorial
Lab. vaje
Labor work
15
Teren. vaje
Field work
Samost. delo
Individ. work
135
ECTS
6
Maja Leitgeb
Predavanja / Lecture: slovenski / Slovene
Vaje / Tutorial: slovenski / Slovene
Pogoji za vključitev v delo oz. za opravljanje
študijskih obveznosti:
Potrebno je znanje iz separacijske tehnike ter
osnovno znanje mikrobiologije, biokemije,
biokemijske tehnike in biotehnologije.
Prerequisites:
Vsebina:
Definicija industrijske mikrobiologije.
Oprema za fermentacijo in njena uporaba.
Rast in nastajanje produktov; gojenje celic, celična
kinetika.
Kinetka biokataliziranih reakcij z dvema ali več
substrati.
Detekcija in analiza fermentacijskih produktov
(fizikalno-kemijske in biološke analize).
Fermentacijski mediji: sestava, sterilizacija,
kontaminacija, cepitev, analiza.
Sterilizacija (šaržna, kontinuirana, sterilizacija
zraka).
Downstream processing (separacija, razbitje celic,
izolacija produktov in njihovo čiščenje).
Industrijski mikroorganizmi.
Industrijski procesi in produkti:
Mikrobni encimi.
Content (Syllabus outline):
Definition of industrial microbiology.
Fermentation equipment and its use.
Industrial microorganisms and products.
Inoculum preparation.
Kinetic of biocatalyzed reactions with two or more
substrates.
Detection and assay of fermentation products
(physical – chemical assays and biological assays).
Fermentation media (composition, sterilization and
contamination, inoculum media).
Sterilization (batch, continuous, sterilization of air).
Industrial microorganisms.
Downstream processing (separation, product
isolation, ...).
Industrial microorganisms.
Industrial processes and products:
Microbial enzymes.
Knowledge of separation processes and basic
knowledge of microbiology, biochemistry,
biochemical engineering and biotechnology is
needed.
28
Antibiotiki: penicilin, streptomicin, drugi antibiotiki.
Anaerobne fermentacije. Glicerol. Vitamini.
Indirektna in direktna fermentacija.
Mikrobna oksidativna transformacija substrata:
vinski kis, glukonska kislina.
Mikrobne celice kot fermentacijski produkti
(pekovski kvas, kvas za prehrano in krmo,
bakterijski insekticidi, glive, alge).
Organske kisline: citronska kislina, fumarna kislina.
Genska kontrola metabolnih poti.
Laboratorijske vaje s področja sterilizacije in
fermentacijskih procesov.
Antibiotic fermentations (penicillin, streptomycin,
and others).
Anaerobic fermentations. Glycerol. Vitamins.
Indirect and direct fermentation.
Microbial oxidative transformations of substrate:
vinegar, gluconic acid.
Microbial cells as fermentation products (bakers’
yeast, food and feed yeasts, bacterial insecticides,
mushrooms, algae).
Organic acids (citric acid, fumaric acid).
Genetic control of metabolic pathways.
Laboratory work in the field of sterilization and
fermentation processes.
Temeljni literatura in viri / Textbooks:
 M. J. Waites, N. L. Morgan, J. S. Rockey, G. Highton, Industrial Microbiology, Blackwell Publishing,
London, 2004.
Dodatna priporočena literatura:
 L. E. Casida, Industrial microbiology, John Wiley and Sons, New York, 2003.
 M. T. Madigar, J. M. Martinko, D. Stahl, D. P. Clark, Brock Biology of Microorganisms, 13 th ed., Prentice
Hall, London, 2010.
 Murray R. K., Granner D. K., Mayes P. A., Rodwell V. W. Harper’s Biochemistry, 24th ed. Prentice Hall,
London, 2010.
 G. Lear, G. D. Lewis, Microbial Biofilms: Current Research and Applications, Caister Academic Press,
New Zealand, 2012.
Cilji in kompetence:
Pregled znanj s področja industrijske
mikrobiologije; od izolacije kultur, njihove
ohranitve, proizvodnje določenih produktov, do
načrtovanja fermentacijskih procesov.
Objectives and competences:
Overview of knowledge in the field of industrial
microbiology; from isolation of cultures, their
preservation, production of desired products, to
design of fermentation processes.
Predvideni študijski rezultati:
Znanje in razumevanje:
Uporaba mikroorganizmov z njihovimi zelo
različnimi metabolnimi aktivnostmi za industrijske
aplikacije – procese in produkte z visoko
ekonomskim, okoljskim in socialnim pomenom.
Intended learning outcomes:
Knowledge and Understanding:
The use of microorganisms, with their extremely
diverse metabolic activities, for industrial
applications – processes and products that are of
major economic, environmental and social
importance.
Prenesljive/ključne spretnosti in drugi atributi:
Predmet se dopoljnjuje z ostalimi vsebinami smeri
Biokemijska tehnika.
Transferable/Key Skills and other attributes:
The subject is related to the other subjects on the
study field Biochemical engineering.
Metode poučevanja in učenja:
Predavanja v učilnici, ki je opremljena z avdiovizualnimi pripomočki.
Individualna priprava seminarskih nalog s
predstavitvijo in diskusijo.
Laboratorijsko delo na izbranem primeru.
Learning and teaching methods:
Lectures in lecture room, equipped with audio-visual
equipment
Individual preparation of seminars and their
presentation with discussion.
Laboratory work on selected case.
29
Načini ocenjevanja:
Izpit je opravljen, če so pozitivno
opravljene vse naslednje obveznosti:
- laboratorijske vaje (dnevnik, kolokvij)
- pisni izpit
- ustni izpit
Delež (v %) /
Weight (in %)
20
40
40
Assessment:
Student has to pass successfully the
following obligations:
- completed lab work (report, colloquium)
- written examination
- oral examination
Reference nosilca / Lecturer’s references:
LEITGEB, Maja, ČOLNIK, Maja, PRIMOŽIČ, Mateja, ZALAR, Polona, GUNDE-CIMERMAN, Nina, KNEZ, Željko. Activity
of cellulase and [alpha]-amylase from Hortaea werneckii after cell treatment with supercritical carbon dioxide. The
Journal of supercritical fluids, ISSN 0896-8446. 2013, 78, 143-148, doi: 10.1016/j.supflu.2013.03.029. [COBISS.SI-ID
16864790]
ČOLNIK, Maja, PRIMOŽIČ, Mateja, KNEZ, Željko, LEITGEB, Maja. Use of supercritical carbon dioxide for proteins and
alcohol dehydrogenase release from yeast Saccharomyces cerevisiae. The Journal of supercritical fluids, ISSN 08968446. 2012, 65, 11-17, doi: 10.1016/j.supflu.2012.02.018. [COBISS.SI-ID 15901462]
KNEZ, Željko, KAVČIČ, Sabina, GUBICZA, László, BÉLAFI-BAKÓ, Katalin, NÉMETH, Gergely, PRIMOŽIČ, Mateja,
LEITGEB, Maja. Lipase-catalyzed esterification of lactic acid in supercritical carbon dioxide. The Journal of
supercritical fluids, ISSN 0896-8446. 2012, 66, 192-197, doi: 10.1016/j.supflu.2011.11. [COBISS.SI-ID 15598102]
ŠULEK, Franja, PÉREZ FERNÁNDEZ, Daniel, KNEZ, Željko, LEITGEB, Maja, SHELDON, Roger A. Immobilization of
horseradish peroxidase as crosslinked enzyme aggregates (CLEAs). Process biochemistry, ISSN 1359-5113, 2011, 46
(3), 765-769, doi: 10.1016/j.procbio.2010.12.001. [COBISS.SI-ID 14712598]
KAVČIČ, Sabina, KNEZ, Željko, LEITGEB, Maja. Antimicrobial activity of n-butyl lactate obtained via enzymatic
esterification of lactic acid with n-butanol in supercritical trifluoromethane. The Journal of supercritical fluids, ISSN
0896-8446. 2014, 85, 143-150, doi: 10.1016/j.supflu.2013.11.003. [COBISS.SI-ID 17392406]
30
Pripravljalni in zaključni procesi
Predmet:
Course title:
UČNI NAČRT PREDMETA / COURSE SYLLABUS
Pripravljalni in zaključni procesi
Upstream / Downstream Processes
Študijski program in stopnja
Study programme and level
Študijska smer
Study field
Letnik
Academic year
Semester
Semester
Kemijska tehnika / 2. stopnja
Chemical Engineering / 2nd level
Kemijska tehnika
Chemical engineering
2.
zimski
Autumn
Vrsta predmeta / Course type:
Obvezni / Obligatory
Univerzitetna koda predmeta / University course code:
Predavanja
Lectures
Seminar
Seminar
Sem. vaje
Tutorial
30
Nosilec predmeta / Lecturer:
Jeziki /
Languages:
Lab. vaje
Laboratory
work
30
Teren. vaje
Field work
Samost. delo
Individ. work
ECTS
120
6
Željko Knez
Predavanja / Lectures: slovenski / Slovene
Vaje / Tutorial: slovenski / Slovene
Pogoji za vključitev v delo oz. za opravljanje
študijskih obveznosti:
Pojmi in osnovna znanja s področij industrijske
stehiometrije, energetske bilance kemijskih
sistemov in proizvodnje produktov.
Prerequisits:
Basic knowledege in the field of industrial
stochiometry, energetic balance of chemical
systems and production of products.
Vsebina:
 Osnove industrijskih pripravljalnih in zaključnih
procesov za različne vrste produktov.
 Načrtovanje in razvoj strategij pripravljalnih in
zaključnih procesov; Primerjava pripravljalnih
in zaključnih procesov.
 Različni separacijski tehnološki postopki
(uparjanje, centrifugiranje, konvencionalna in
membranska filtracija, postopki obarjanja,
kristalizacija, procesna kromatografija, ...) in
njihova učinkovitost.
 Izhodišča raziskav (case study) in razvoj
celotnega procesa.
Content (Syllabus outline):
 General introduction to industrial downstream
and upstream processes for different products.
 Process design and development of
downstream processing (upstream versus
downstream).
 Different separation technological processes
(evaporation, centrifugation, conventional and
membrane filtration, precipitation processes,
crystallization, process chromatography,...) and
their effectiveness.
 Case studies and development of the complete
process.
V okviru laboratorijskih vaj se izvaja superkritična
Laboratory work includes supercritical extraction,
antimicrobial activity of extract, micronisation,
31
ekstrakcija, protibakterijsko delovanje ekstrakta,
mikronizacija, superkritična kormatografija.
supercritical chromatography.
Temeljni literatura in viri / Readings:
 B. Elvers, S. Hawkins, W. E Russey: Ullmann's encyclopedia of industrial chemistry, izbrana poglavja,
Weinheim, Cambridge: Wiley-VCH, 2003.
Dodatna priporočena literatura:
 J. Nielsen, J. Villadsen, G. Liden, Bioreaction Engineering Principles, 2nd ed., Kluwer Academic/Plenum
Publishers, 2003.
 M. C. Flickinger, Downstream Industrial Biotechnology: Recovery and Purification, Wiley, 2013, ISBN:
978-1-118-13124-4.
Cilji in kompetence:
- Priprava surovin in obdelava produktov v
industriji.
- Pravilna razporeditev produktnih enot za
obdelavo (čiščenje) določenega produkta.
- Povezava med pripravljalnimi in zaključnimi
procesi.
- Pomembnost čistote produkta v razvoju in
načrtovanju v pripravljalnih procesih.
- Obdelava (študij) rezultatov realnih primerov
in njihova uporaba za izbiro procesnih pogojev
za določeno operacijo.
- Izračun operativnih parametrov za določeno
operacijsko enoto pripravljalnega procesa.
Objectives and competences:
- Preparation of raw materials and product
processing in industry.
- Appropriate arrangement of unit operations for
the processing (purification) of a given type of a
product.
- Interplay between upstream and downstream
processes.
- Importance of product purity during
development and planning of upstream
processes.
- Results processing (study) of real examples and
their use for the selection of process conditions
for specific operation.
- Calculation of operating parameters for a given
downstream unit operation process.
Predvideni študijski rezultati:
Znanje in razumevanje:
Zmožnost načrtovanja pripravljalnih in zaključnih
procesov za komercialno pomembne substance.
Intended learning outcomes:
Knowledge and understanding:
The ability to design of upstream / downstream
processes for commercially important compounds.
Prenesljive/ključne spretnosti in drugi atributi:
Vsebina predmeta je povezana z ostalimi predmeti
na smeri Kemijska tehnika in podaja znanja,
potrebna za lažje razumevanje vsebin, ki so zajete
npr. pri predmetu Farmacevtska tehnika.
Transferable/Key Skills and other attributes:
The subject is connected to other subjects on the
direction Chemical engineering and gives the
knowledge which is necessary for understanding
other subjects such as Pharmaceutical technology.
Metode poučevanja in učenja:
- predavanja
- laboratorijske vaje
Learning and teaching methods:
- lectures
- laboratory work
Načini ocenjevanja:
Izpit je opravljen, če so pozitivno
opravljene vse naslednje obveznosti:
- pisni izpit
- ustni izpit
- laboratorijske vaje
Delež (v %) /
Weight (in %)
60
30
10
32
Assessment:
Student has to pass successfully the
following obligations:
- written examination
- oral examination
- laboratory work
Reference nosilca / Lecturer’s references:
KNEZ, Željko, ŠKERGET, Mojca, KNEZ HRNČIČ, Maša. Principles of supercritical fluid extraction and applications in
the food, beverage and nutraceutical industries. V: RIZVI, Syed S. H. (ur.). Separation, extraction and concentration
processes in the food, beverage and nutraceutical industries. Oxford [etc.]: Woodhead Publishing Limited, 2010,
str. [3]-38.
MARKOČIČ, Elena, ŠKERGET, Mojca, KNEZ, Željko. Polylactide and poly(lactide-co-glycolide) processed with
supercritical CO2 for biomedical applications. V: FELTON, Gary P. (ur.). Biodegradable polymers : processing,
degradation and applications. Hauppauge, N.Y.: Nova Science Publishers, 2011, str. [517]-543.
KNEZ, Željko, FRITSCH, Markus, SCHULZE, Joachim, LÜTGE, Christoph. Process for the purification of carboxylic
acids by subcritical or supercritical fluid chromatography : European patent application no. 2745905 A1, date of
publication: 25. 06. 2014 Bulletin 2014/26; appl. no.: 12008534.5, date of filling: 21. 12. 2012. Munich:
Europäisches Patentamt: = European Patent Office: = Office européen des brevets, 2014.
KNEZ, Željko, ŠKERGET, Mojca, KNEZ HRNČIČ, Maša, ČUČEK, Denis. Particle formation using sub- and supercritical
fluids. V: ANIKEEV, Vladimir (ur.), FAN, Maohong (ur.). Supercritical fluid technology for energy and environmental
applications. Amsterdam: Elsevier, 2014, str. 31-67.
33
Energetski management procesov
Predmet:
Course title:
UČNI NAČRT PREDMETA / COURSE SYLLABUS
Energetski management procesov
Energy Management of Processes
Študijski program in stopnja
Study programme and level
Kemijska tehnika / 2. stopnja
Chemical Engineering / 2nd level
Študijska smer
Study field
Kemijska tehnika
Chemical Engineering
Vrsta predmeta / Course type:
Letnik
Academic year
2.
Semester
Semester
zimski
Autumn
Obvezni / Obligatory
Univerzitetna koda predmeta / University course code:
Predavanja
Lectures
Seminar
Seminar
Sem. vaje
Tutorials
30
Nosilec predmeta / Lecturer:
Jeziki /
Languages:
Lab. vaje
Laboratory
work
30
Teren. vaje
Field work
Samost. delo
Individ. work
ECTS
120
6
Darko Goričanec
Predavanja / Lecture: slovenski / Slovene
Vaje / Tutorial: slovenski / Slovene
Pogoji za vključitev v delo oz. za opravljanje
študijskih obveznosti:
Ni pogojev.
Prerequisites:
Vsebina:
 Energetske razmere v svetu
 Vrste energije, namen uporabe, razlogi za
varčevanje
 Tehnični in praktični vidiki izkoriščanja virov
energije
 Aktivni sistemi za izkoriščanje virov energije
 Racionalizacija uporabe energije v industriji
 Energijske pretvorbe v tehnoloških procesih
 Tehnologije za izkoriščanje odpadne toplote in
vrednotenje investicij v smislu racionalizacije
 Značilni primeri energetskih ukrepov v kemijski
procesni industrij
 Energetski pregledi
 Možni ukrepi za zmanjšanje porabe energije
(predlogi izboljšav sistemov oskrbe z energijo)
 Analiza ukrepov za zmanjšanje porabe energije
Content (Syllabus outline):
 Energy situation in the world
 Energy types, purpose, reasons for energy savings
 Technical and practical aspect of exploiting
energy sources
 Active systems for exploitation of energy sources
 Rationalization of the use of energy in industry
 Energy transformations during technological
processes
 Technology for exploiting waste heat and
evaluating the rationality of investments
 Significant examples for measures taken in
chemical process industry
 Energy revision
 Measures taken to reduce the consumption of
energy (suggestions to improve the systems for
supply of energy)
None.
34
(potrebna investicijska sredstva, prihranki,
ekološka presoja, doba vračila, lista ukrepov)
 Metode dinamičnega izračuna gospodarnosti
energetskih postrojev
Vaje: Študent samostojno reši več praktičnih
primerov in izdela krajšo projektno nalogo.
 Analysis of measures to reduce consumption of
energy (the investment assets needed, savings,
ecological evaluation, list of measures)
 Methods of dynamic calculation of economic
efficiency energy systems
Exercises: Student individually solve the more
practical examples and short process design
formulation.
Temeljni literatura in viri / Textbooks:
 Capehart, B. L., Turner, W. C., Kennedy, W. J., Guide to energy management, 6th Edition, 2008.
Dodatna priporočena literatura:
 A. P. Rossiter, B. P. Jones, Energy Management and Efficiency for the Process Industries, AIChE, 2015.
 Turner W., Energy management handbook, Fairmont press, Liburn, 2001.
 Aldo V da Rosa, Fundamentals of renewable energy processes, academic Press, august 3, 2005.
 John Twidell, Renewable energy resources, Taylor&Francis. 2nd edition, December 16, 2005.
Cilji in kompetence:
 Študent se seznani s praktičnimi možnostmi za
boljšo energetsko izobrazbo (npr. varčevanje z
energijo, večji izkoristki v transformacijah
energije) in izkoriščanje obnovljivih virov.
 Razvoj strokovnih spretnosti – spretnosti pri
skupinskem delu in reševanju problemov.
Objectives and competences:
 The student will acquire practical knowledge
regarding the energy sector, such as saving the
energy, increasing the efficiency while
transforming the energy and using the renewable
energy sources.
 Development of professional skills – skills in team
work and problem.
Predvideni študijski rezultati:
Znanje in razumevanje:
 Možnost ocene primerjave količinskih in
kakovostnih vplivov ukrepov na rabo energije in
na emisije
 Kaj je energetski pregled podjetja?
 Katere spremembe v energetski porabi so nujne?
 Razumevanje osnovnih principov o možnostih
izkoriščanja obnovljivih virov energije
Intended learning outcomes:
Knowledge and Understanding:
 Learning how to evaluate and compare the
quantitative and qualitative effects of measures
taken for the se of energy and emissions
 What is power assessment of a factory?
 What changes in power use of an enterprise are
mandated through an assessment?
 Understanding the fundamental principles of the
possibility of exploiting renewable energy sources
Prenesljive/ključne spretnosti in drugi atributi:
 Sposobnost prenosa teoretičnih spoznanj na manj
teoretično okolje in njihova uporaba za določitev
primernih energetskih virov in njihove uporabe
 Sposobnost spremljanja sprememb, ki nastaja pri
izvajanju energetske zasnove in racionalne rabe
energije
Transferable/Key Skills and other attributes:
 Ability to transfer theoretical knowledge in less
theoretical environment and use of this
knowledge to determine energy sources and
sensible use of energy sources
 Acquiring the knowledge to follow the changes
arising when preparing the energy base and when
using the energy rationally
Metode poučevanja in učenja:
 predavanja
 obravnava študijskih primerov
 aktivno skupinsko delo
Learning and teaching methods:
 lectures
 field work
 active team work
35
Načini ocenjevanja:
Izpit je opravljen, če so pozitivno
opravljene vse naslednje obveznosti:
 seminarska naloga
 teoretični del izpita
 računski del izpita
Delež (v %) /
Weight (in %)
20
30
50
Teoretični in računski del tvorita celoto in se
preverjata hkrati.
Assessment:
Student has to pass successfully the
following obligations:



seminar
theoretical part of the exam
calculation part of the exam
The theoretical and the calculus part of exam are
performed simultaneously.
Reference nosilca / Lecturer’s references:
DOBERŠEK, Danijela, GORIČANEC, Darko. An experimentally evaluated magnetic device's efficiency for water-scale
reduction on electric heaters. Energy, ISSN 0360-5442. [Print ed.], Available online 27 September 2014, str. 1-8.
SORŠAK, Marko, ŽEGARAC LESKOVAR, Vesna, PREMROV, Miroslav, GORIČANEC, Darko, PŠUNDER, Igor. Economical
optimization of energy-efficient timber buildings: Case study for single family timber house in Slovenia. Energy,
ISSN 0360-5442. [Print ed.], Article in Press 2014, str. 1-9.
GORIČANEC, Darko, POZEB, Viljem, TOMŠIČ, Ladislav, TROP, Peter. Exploitation of the waste-heat from hydro
power plants. Energy, ISSN 0360-5442. [Print ed.], Available online 22 July 2014, str. 1-6, doi:
10.1016/j.energy.2014.06.106. [COBISS.SI-ID 17986326].
KULČAR, Bojan, GORIČANEC, Darko, KROPE, Jurij. Economy of replacing a refrigerant in a cooling system for
preparing chilled water = Remplacement du frigorigene dans un systeme utilisé pour préparer de l'eau glacée :
impact financier. International journal of refrigeration, ISSN 0140-7007. [Print ed.], Aug. 2010, vol. 33, iss. 5, str.
989-994.
ŽLAK, Janez, AGREŽ, Marko, DOBERŠEK, Danijela, GORIČANEC, Darko, KROPE, Jurij. Rentability of rotary heat
regenerator use in ventilating systems = Rentabilnost upotrebe regeneratora topline u ventilacijskom sustavu.
Strojarstvo, ISSN 0562-1887, 2010, vol. 52, no. 6, str. 665-671.
36
Sinteza procesov
Predmet:
Course title:
UČNI NAČRT PREDMETA / COURSE SYLLABUS
Sinteza procesov
Process Synthesis
Študijski program in stopnja
Study programme and level
Kemijska tehnika / 2. stopnja
Chemical Engineering / 2nd level
Študijska smer
Study field
Kemijska tehnika
Chemical Engineering
Vrsta predmeta / Course type:
Letnik
Academic year
2.
Semester
Semester
zimski
autumn
Obvezni / Obligatory
Univerzitetna koda predmeta / University course code:
Predavanja
Lectures
30
Seminar
Seminar
Nosilec predmeta / Lecturer:
Jeziki /
Languages:
Sem. vaje
Tutorial
Lab. vaje
Labor work
30
Teren. vaje
Field work
Samost. delo
Individ. work
120
ECTS
6
Zdravko Kravanja
Predavanja / Lecture: slovenski / Slovene
Vaje / Tutorial: slovenski / Slovene
Pogoji za vključitev v delo oz. za opravljanje
študijskih obveznosti:
Osnovna znanja iz načrtovanja in optimiranja
procesov
Prerequisites:
Vsebina:
Osnovni koncepti algoritemskih metod:
 predstavitev problema z drevesno in mrežno
predstavitvijo,
 alternativne formulacije za matematično
programiranje,
 modeliranje logičnih pogojev in disjunkcij.
Content (Syllabus outline):
Basic concepts of algorithmic methods:
 Tree and network problem representations.
 Alternative mathematical programming
formulations.
 Modeling of logical constraints and disjunctives.
Sinteza destilacijskih zaporedij:
 linearni model kolon z ostro separacijo,
 mešano-celoštevilski model za destilacijska
zaporedja,
 toplotno integrirana destilacijska zaporedja.
Sinteza reakcijskih omrežij:
 koncept dosegljivega območja,
 sinteza reakcijskih omrežij s ciljano
formulacijo,
 sinteza reakcijskega omrežja v celotni procesni
shemi.
Basic knowledge of process design and optimization
Synthesis of distillation sequences:
 Linear model for sharp split columns.
 Mixed-integer linear model for distillation
sequences.
 Heat integrated distillation sequences.
Reactor network synthesis:
 Geometrical concept for attainable region.
 Synthesis of reactor networks with a targeting
formulation.
 Reactor network synthesis in overall process
scheme.
Synthesis of overall process schemes:
37
 Superstructure representation of:
basic subsystems,
overall process schemes.
 Process synthesizer MIPSN.
Sinteza celotnih procesnih shem:
 definiranje superstrukture:
- osnovnih podsistemov,
- celotnih procesov,
 procesni sintetizer MIPSYN.
Computer room: synthesis of process systems.
Računalniške vaje iz sinteze procesnih sistemov.
Temeljni literatura in viri / Textbooks:


Biegler L.T., I.E.Grossmann and A.W.Westerberg, Systematic Methods of Chemical Process Design,
Prentice Hall, New Jersey, 1999.
A. Brooke, D. Kendrick, A. Meeraus, R. Raman, GAMS - A user Guide, Scientific Press, GAMS
Development Corporation, 2015. http://www.gams.com/dd/docs/bigdocs/GAMSUsersGuide.pdf
Cilji in kompetence:
Cilj je podati podrobnejše znanje o sintezi procesov
in procesnih podsistemov.
Objectives and competences:
The aim is to give knowledge of synthesis of process
schemes and their subsystems in more details.
Predvideni študijski rezultati:
Znanje in razumevanje:
Obvladovanje teorije in aplikacij matematičnega
programiranja (optimiranja) pri sintezi kemijskih in
biokemijskih procesov ter njihovih podsistemov.
Intended learning outcomes:
Knowledge and Understanding:
Understand theory and have knowledge of some
practical applications of mathematical programming
in synthesizing (bio)chemical processes and their
subsystems.
Transferable/Key Skills and other attributes:
To have an understanding of the impact of synthesis
solutions on safe, environmentally benign and
economically effective operation of chemical and
biochemical processes.
Prenesljive/ključne spretnosti in drugi atributi:
Imeti razumevanje o vplivu sinteznih rešitev na
varno, okolju prijazno in ekonomsko učinkovito
delovanje kemijskih in biokemijskih procesov.
Metode poučevanja in učenja:
Predavanja, seminar in računalniške vaje.
Samostojno delo študenta.
Načini ocenjevanja:
Izpit je opravljen, če sta pozitivno
opravljeni naslednji obveznosti:
 seminarska naloga
 predstavitev seminarske naloge
Learning and teaching methods:
Lectures, seminar work, and computer practice.
Self-learning.
Delež (v %) /
Weight (in %)
Assessment:
Student has to pass successfully the
following obligations:
 Seminar work
70
30
 Presentation of the seminar work
Reference nosilca / Lecturer’s references:
AHMETOVIĆ, Elvis, KRAVANJA, Zdravko. Simultaneous optimization of heat-integrated water networks involving
process-to-process streams for heat integration. Applied thermal engineering, ISSN 1359-4311. [Print ed.], Jan.
2014, vol. 62, iss. 1, str. 302-217, doi: 10.1016/j.applthermaleng.2013.06.010.
NEMET, Andreja, KLEMEŠ, Jiri, KRAVANJA, Zdravko. Designing a Total Site for an entire lifetime under fluctuating
utility prices. Computers & chemical engineering, ISSN 0098-1354. [Print ed.], Available online 18 July 2014, vol. ,
str. 1-24, doi: 10.1016/j.compchemeng.2014.07.004.
ČUČEK, Lidija, MARTÍN, Mariano, GROSSMANN, Ignacio E., KRAVANJA, Zdravko. Multi-period synthesis of
optimally-integrated biomass and bioenergy supply network. Computers & chemical engineering, ISSN 0098-1354.
[Print ed.], 4 Jul. 2014, vol. 66, str. 57-70, doi: 10.1016/j.compchemeng.2014.02.020.
KRAVANJA, Zdravko, ČUČEK, Lidija. Multi-objective optimisation for generating sustainable solutions considering
total effects on the environment. V: DUIĆ, Neven (ur.). Sustainable development of energy, water and environment
systems, (Applied Energy, ISSN 0306-2619, Vol. 101, (2012)). Oxford: Elsevier, cop. 2012, vol. 101, str. 67-80, doi:
38
10.1016/j.apenergy.2012.04.025.
ČUČEK, Lidija, KLEMEŠ, Jiri, KRAVANJA, Zdravko. A Review of Footprint analysis tools for monitoring impacts on
sustainability. Journal of cleaner production, ISSN 0959-6526. [Print ed.], Oct. 2012, vol. 34, str. 9-20, doi:
10.1016/j.jclepro.2012.02.036.
39
Procesne surovine za bio in prehrambeno industrijo
Predmet:
Course title:
UČNI NAČRT PREDMETA / COURSE SYLLABUS
Procesne surovine za bio in prehrambeno industrijo
Process Raw Materials for Bio and Food Industry
Študijski program in stopnja
Study programme and level
Kemijska tehnika / 2. stopnja
Chemical Engineering / 2nd level
Študijska smer
Study field
Biokemijska tehnika
Biochemical Engineering
Vrsta predmeta / Course type:
Letnik
Academic year
2.
Semester
Semester
zimski
Autumn
Obvezni / Obligatory
Univerzitetna koda predmeta / University course code:
Predavanja
Lectures
30
Seminar
Seminar
Nosilec predmeta / Lecturer:
Jeziki /
Languages:
Sem. vaje
Tutorial
Lab. vaje
Labor work
30
Teren. vaje
Field work
Samost. delo
Individ. work
120
ECTS
6
Zoran Novak
Predavanja / Lecture: slovenski / Slovene
Vaje / Tutorial: slovenski / Slovene
Pogoji za vključitev v delo oz. za opravljanje
študijskih obveznosti:
Potrebno je znanje iz separacijske tehnike,
mikrobiologije, biokemije, biokemijske tehnike,
industrijske mikrobiologije in biotehnologije.
Prerequisites:
Vsebina:
- Uvod
- Prevzem in skladiščenje surovin.
- Priprava surovin (čiščenje, sortiranje, luščenje).
- Surovine v biotehnoloških procesih za
proizvodnjo živil in krmil živalskega in
rastlinskega izvora.
- Surovine v fermentacijski industriji.
- Biomasa - biološka surovina, proizvedena iz
rastlin in živali.
- Surovine za proizvodnjo biomase in njihova
priprava (surovine v trdnem, tekočem in
plinastem stanju).
- Mikroorganizmi za proizvodnjo biomase.
- Procesi in aparature.
- Primeri.
Content (Syllabus outline):
- Introduction
- Raw materials in food industries
- Storage of raw materials.
- Preparation of raw materials.
- Raw materials of animal and vegetal source in
biotechnological processes for production of
food and feeding stuff.
- Raw materials in fermentation industry.
- Biomass from plant and animal origin.
- Raw materials for biomass production and their
preparation.
- Microorganisms for biomass production.
- Processes and apparatus.
- Examples.
Laboratorijske vaje iz področja kontrole surovin v
bio industriji.
Laboratory work on the case of raw material control
in bio-industry.
Knowledge of separation processes, microbiology,
biochemistry, biochemical engineering, industrial
microbiology and biotechnology is needed.
40
Temeljni literatura in viri / Textbooks:
 P. Fellows, Food Processing Technology: Principles and Practice, 3rd ed., CRC Press, USA, 2009.
Dodatna priporočena literatura:
 S. Gad, Handbook of Pharmaceutical Biotechnology Pharmaceutical Development, Wiley-VCH,
Weinheim, 2007.
 M. C. Flickinger, Upstream and Downstream Industrial Biotechnology, 3V Bundle, Wiley, ISBN: 978-1118-13125-1, 2014.
 M. C. Flickinger, Encyclopedia of Industrial Biotechnology, Bioprocess, Bioseparation, and Cell
Technology , 7 Volume Set, Wiley, ISBN: 978-0-471-79930-6, 2010.
Cilji in kompetence:
Razumevanje tehnik priprave surovin v industrijske
namene.
Objectives and competences:
Understanding of techniques for raw materials
preparation in industrial use.
Predvideni študijski rezultati:
Znanje in razumevanje:
Optimalna izbira surovin glede na zahteve nadaljne
predelave oz. biosinteze ter ekonomike
proizvodnje.
Intended learning outcomes:
Knowledge and Understanding:
Optimal selection of raw materials, considering
further application or biosynthesis and economic of
the process.
Prenesljive/ključne spretnosti in drugi atributi:
Predmet se dopoljnjuje z ostalimi vsebinami na
smeri Biokemijska tehnika.
Transferable/Key Skills and other attributes:
The subject is related to the other subjects on the
study feild Biochemical engineering.
Metode poučevanja in učenja:
Predavanja v učilnici, ki je opremljena z avdiovizualnimi pripomočki.
Individualna priprava seminarskih nalog s
predstavitvijo in diskusijo.
Laboratorijsko delo na izbranem primeru.
Learning and teaching methods:
Lectures in lecture room, equipped with audio-visual
equipment
Individual preparation of seminars and their
presentation with discussion.
Laboratory work on a selected case.
Načini ocenjevanja:
Izpit je opravljen, če so pozitivno
opravljene vse naslednje obveznosti:
- laboratorijske vaje (dnevnik, kolokvij)
- pisni izpit
- ustni izpit
Delež (v %) /
Weight (in %)
20
60
20
Assessment:
Student has to pass successfully the
following obligations:
- laboratory work (report, colloquium)
- written examination
- oral examination
Reference nosilca / Lecturer’s references:
KNEZ, Željko, AIONICESEI, Elena, NOVAK, Zoran, KNEZ HRNČIČ, Maša. Processing polymeric biomaterials using
supercritical CO[sub]2. Chemieingenieurtech., 2011, vol. 83, no. 9, str. 1371-1380. [COBISS.SI-ID 15347734]
VERONOVSKI, Anja, NOVAK, Zoran, KNEZ, Željko. Synthesis and use of organic biodegradable aerogels as drug
carriers. Journal of biomaterials science, Polymer edition, ISSN 0920-5063, 2012, vol. 23, no. 7, str. 873-886., doi:
10.1163/092050611X566126. [COBISS.SI-ID 15819286],
VERONOVSKI, Anja, TKALEC, Gabrijela, KNEZ, Željko, NOVAK, Zoran. Characterisation of biodegradable pectin
aerogels and their potential use as drug carriers. Carbohydrate polymers, ISSN 0144-8617. [Print ed.], 26 Nov.
2014, vol. 113, str. 272-278, doi: 10.1016/j.carbpol.2014.06.054. [COBISS.SI-ID 18000150]
HE, Li, ZHANG, Xiaofei, XU, Honggao, XU, Chao, YUAN, Fang, KNEZ, Željko, NOVAK, Zoran, GAO, Yanxiang.
Subcritical water extraction of phenolic compounds from pomegranate (Punica granatum L.) seed residues and
investigation into their antioxidant activities with HPLC-ABTS assay. Food and bioproducts processing, ISSN 09603085, Apr. 2012, vol. 90, iss. 2, str. 215-223, doi: 10.1016/j.fbp.2011.03.003. [COBISS.SI-ID 14920470]
41
Sodobne procesne tehnike v živilstvu
Predmet:
Course title:
UČNI NAČRT PREDMETA / COURSE SYLLABUS
Sodobne procesne tehnike v živilstvu
Modern Process Operations in Food Engineering
Študijski program in stopnja
Study programme and level
Kemijska tehnika / 2. stopnja
Chemical Engineering / 2nd level
Študijska smer
Study field
Biokemijska tehnika
Biochemical Engineering
Vrsta predmeta / Course type:
Letnik
Academic year
2.
Semester
Semester
zimski
Autumn
Obvezni / Obligatory
Univerzitetna koda predmeta / University course code:
Predavanja
Lectures
30
Seminar
Seminar
Nosilec predmeta / Lecturer:
Jeziki /
Languages:
Sem. vaje
Tutorial
Lab. vaje
Labor work
30
Teren. vaje
Field work
Samost. delo
Individ. work
120
ECTS
6
Mojca Škerget
Predavanja / Lecture: slovenski/Slovene
Vaje / Tutorial: slovenski/Slovene
Pogoji za vključitev v delo oz. za opravljanje
študijskih obveznosti:
Osnovno znanje prenosnih pojavov (prenos toplote
in snovi) in osnovnih procesnih operacij.
Prerequisits:
Vsebina:
 Reologija živilskih izdelkov:osnovni pojmi,
reološka klasifikacija fluidov, reološki modeli,
vpliv temperature in vpliv koncentracije na
viskoznost.
 Termične lastnosti živilskih izdelkov: toplotna
prevodnost, specifična toplotna kapaciteta,
gostota, termična difuzivnost.
 Načrtovanje postopkov termičnega
procesiranja živil – sterilizacija: hitrost termične
inaktivacije, procesiranje konzerviranih
produktov, aseptični postopek procesiranja
tekočin.
 Načrtovanje postopkov konzerviranja živil s
hlajenjem: zamrzovanje, temperatura zmrzišča,
termične lastnosti zamrznjenih živil, čas
zamrzovanja, načrtovanje zamrzovalnega
sistema, hlajenje in hladilni sistemi.
 Sodobni tehnološki postopki v predelavi živil:
priprava snovi, membranske operacije,
Content (Syllabus outline):
 Rheology of food products: fundamentals,
rheological classification of food products,
rheological models, influence of temperature
and concentration on viscosity.
 Thermal properties of food: thermal
conductivity, specific heat, density, thermal
diffusivity.
 Thermal processing of foods: thermal death
rate, treatment of canned products, aseptic
processing of liquid products.
 Food preservation by cooling: freezing, freezing
temperature, thermal properties of frozen
foods, freezing time, design of freezing systems,
refrigeration and refrigeration systems.
 Emerging technologies for food processing:
Preparation of material, membrane processes,
pasterization and sterilization by high pressure
processing, encapsulation technologies for
active food ingredients and functional foods,
Basic knowledge on transport phenomena (heat and
mass transfer) and unit operations.
42



pasterizacija in sterilizacija z visokimi tlaki,
enkapsulacija komponent in vgradnja v
funkcionalna živila, pridobivanje praškastih
produktov s superkritičnimi fluidi.
vpliv procesiranja na kvaliteto prehrambenih
izdelkov: kemijske spremembe pri procesiranju
in načrtovanje končnih produktov.
pakiranje izdelkov, permeabilnost,
pokvarljivost in rok trajanja: namen, nivoji
pakiranja in embalažni materiali, načini
pakiranja, prepustnost embalažnih materialov
za pline in paro.
Proizvodne tehnologije izbranih skupin
prehrambenih izdelkov.
Laboratorijske vaje:
- Reološke lastnosti živilskih izdelkov,
- Enkapsulacija aktivnih komponent in testi
stabilnosti.



production of powderous products by
supercritical fluid technologies.
Effects of food processing on quality of foods:
chemical changes during processing and design
of products with tailor-made properties;
Food packing, permeability and Shelf-Life:
functions of packing, levels of packing and
materials, types of packing, permeability for
gasses and vapour.
Procesing technology of selected food product
groups.
Laboratory work:
 Rheological properties of foods,
 Encapsulation of active compounds and stability
tests.
Temeljni literatura in viri / Textbooks:
 A. Ibarz, G.V. Barbosa-Cánovas, Unit Operations in Food Engineering, CRC Press, Boca Raton, 2003.
 Emerging technologies for food processing, Ed.: D.-W. Sun, Elsevier Ltd., 2005.
Dodatna priporočena literatura:
 Food Processing Handbook, Ed.: J. G.Brennan, Wiley-VCH Verlag GmbH, Weinheim, 2006.
 Food processing Principles and Applications, Eds: J. S. Smith, Y. H. Hui, Blackvell Publishing, 2004
 P. Fellows: Food Processing Technology: Principles and Practice, 2nd ed., Woodland Publishing; 2000.
Cilji in kompetence:
Seznaniti študente s sodobnimi tehnološkimi
postopki in principi in novimi tehnologijami, ki se
uporabljajo za proizvodnjo prehrambenih izdelkov
in sodobnih produktov, ki so narejeni po meri
potrošnika.
Študent bo poznal uporabnost različnih metod za
različne skupine izdelkov in vpliv procesiranja na
kvaliteto izdelka. Znal bo načrtovati in optimirati
posamezne procesne operacije. Poznal bo zahteve
in ukrepe, ki so potrebni za zagotavljanje varnosti
živil v proizvodnji in prometu.
Objectives and competences:
The objective is to introduce the student to the
operations and principles in food processing,
emerging technologies and production of products
with tailor-made properties.
The students should be able to evaluate different
types of unit operations in connection with
treatment of different types of foods and the effects
of processing on quality of foods. They should be
able to design and optimize specific process
operations. They should know the measures and
arrangements which are necessary to assure food
safety in production process and in retail.
Predvideni študijski rezultati:
Znanje in razumevanje:
 sodobnih operacij in principov procesiranja
prehrambenih izdelkov;
 vplivov procesiranja na kvaliteto izdelkov;
 načrtovanje produktov po meri potrošnika;
 načrtovanje in optimiranje posameznih
procesnih operacij;
 zahtev in ukrepov, ki so potrebni za
Intended learning outcomes:
Knowledge and Understanding:
 operations and principles of food processing;
 effects of processing on quality of foods;
 design of products with tailor-made properties;
 design and optimization of process operations;
 measures and arrangements necessary to
assure food safety in production process and in
retail.
43
zagotavljanje varnosti živil v proizvodnji in
prometu.
Prenesljive/ključne spretnosti in drugi atributi:
- znanja za inovativno delo v prehrambeni
industriji
- razvoj novih produktov
Transferable/Key Skills and other attributes:
- Achieving knowledge for inovative work in food
industry
- Development of new products
Metode poučevanja in učenja:
 Predavanja
 Reševanje problemov
 Laboratorijske vaje
Learning and teaching methods:
 Lectures
 Solving problems
 Laboratory work
Načini ocenjevanja:
Način (pisni izpit, ustno izpraševanje,
naloge, projekt)
Ustni izpit
Pisni izpit
Laboratorijske vaje
Delež (v %) /
Weight (in %)
40
30
30
Assessment:
Type (examination, oral, coursework,
project):
Oral examination
Written examination
Labor work
Reference nosilca / Lecturer’s references:
RAVBER, Matej, KNEZ, Željko, ŠKERGET, Mojca. Simultaneous extraction of oil- and water-soluble phase from
sunflower seeds with subcritical water. Food chemistry, ISSN 0308-8146. [Print ed.], Jan. 2015, vol. 166, str. 316323, doi: 10.1016/j.foodchem.2014.06.025. [COBISS.SI-ID 17908502],
PAVLOVIČ, Irena, KNEZ, Željko, ŠKERGET, Mojca. Hydrothermal reactions of agricultural and food processing wastes
in sub- and supercritical water : a review of fundamentals, mechanisms, and state of research. Journal of
agricultural and food chemistry, ISSN 0021-8561, 2013, vol. 61, no. 34, str. 8003-8025, doi: 10.1021/jf401008a.
[COBISS.SI-ID 17077526],
KNEZ, Željko, ŠKERGET, Mojca, KNEZ HRNČIČ, Maša. Principles of supercritical fluid extraction and applications in
the food, beverage and nutraceutical industries. V: RIZVI, Syed S. H. (ur.). Separation, extraction and concentration
processes in the food, beverage and nutraceutical industries. Oxford [etc.]: Woodhead Publishing Limited, 2010,
str. [3]-38. [COBISS.SI-ID 14789910]
VATAI, Tünde, ŠKERGET, Mojca, KNEZ, Željko. Extraction of phenolic compounds from elder berry and different
grape marc varieties using organic solvents and/or supercritical carbon dioxide. Journal of food process
engineering, ISSN 0145-8876, 2009, vol. 90, iss. 2, str. 246-254. http://dx.doi.org/10.1016/j.jfoodeng.2008.06.028,
doi: 10.1016/j.jfoodeng.2008.06.028. [COBISS.SI-ID 12483094],
MANDŽUKA, Zoran, ŠKERGET, Mojca, KNEZ, Željko. High pressure micronization of tristearate. Journal of the
American Oil Chemists' Society, ISSN 0003-021X, Feb. 2010, vol. 87, no. 2, str. 119-125, doi: 10.1007/s11746-0091482-4. [COBISS.SI-ID 13787670],
ŠKERGET, Mojca. Separacija naravnih učinkovin in formulacija produktov: zaključno poročilo o rezultatih
znanstvenoraziskovalnega sodelovanja. Maribor: Fakulteta za kemijo in kemijsko tehnologijo, 2012. [8] f.
[COBISS.SI-ID 15903510]
44
Genomika v biomedicinski tehnologiji
Predmet:
Course title:
UČNI NAČRT PREDMETA / COURSE SYLLABUS
Genomika v biomedicinski tehnologiji
Genomics in Biomedical Technology
Študijski program in stopnja
Study programme and level
Kemijska tehnika / 2. stopnja
Chemical Engineering / 2nd level
Študijska smer
Study field
Biokemijska tehnika
Biochemical Engineering
Vrsta predmeta / Course type:
Letnik
Academic year
2.
Semester
Semester
zimski
Autumn
Obvezni / Obligatory
Univerzitetna koda predmeta / University course code:
Predavanja
Lectures
30
Seminar
Seminar
Nosilec predmeta / Lecturer:
Jeziki /
Languages:
Sem. vaje
Tutorial
Lab. vaje
Labor work
30
Teren. vaje
Field work
Samost. delo
Individ. work
120
ECTS
6
Uroš Potočnik
Predavanja / Lecture: slovenski / Slovene
Vaje / Tutorial: slovenski / Slovene
Pogoji za vključitev v delo oz. za opravljanje
študijskih obveznosti:
Pogojev ni.
Prerequisites:
Vsebina:
Osnove toksikologije in farmakogenomike
tehnologije v genomiki: nanotehnologija,
mikromreže (biočipi), tehnologija za avtomatsko
gensko tipizacije enonukleotidnih polimorfizmov v
celotnem genomu (SNPov), sekvenciranje celotnih
genomov, Maldi-TOF, 2-D elektroforeza
genomika in odkrivanje novih zdravil
genomika raka
asociacijske študija za odkrivanje novih genov
povezanih s kompleksnimi boleznimi (avtoimunske
bolezni, rak, astma, sladkorna…)
funkcijska genomika
transkriptomika
fiziološka genomika
primerjalna (komparativna ) genomika
mikrobna genomika
proteomika
bioinformatika
genetski testi v diagnostiki bolezni
Content (Syllabus outline):
Basics toxicology and pharmacogenomics
genomic technologies: nanotechnology, microarrays
(Biochips), whole genome genotyping of Single
nucleotide Polymorphisms (SNPs), Maldi-TOF, 2-D
electrophoresis
genomics in drug discovery
cancer genomics
disease association study in common complex
diseases (autoimmune diseases, cancer, asthma,
diabetes…)
functional genomics
transcriptomics
physiological genomics
comparative genomics
genomics of microorganisms
proteomics
bioinformatics
statistical genetics and disease association analysis
Genetics in diagnosis
None.
45
genska terapija
etika v genomiki
Hibridizacije nukleinskih kislin, mikromreže
Pomnoževanje molekul DNA v pogojih in vitro
(PCR), Sekvenciranje DNA
Dvohibridni kvasni sistem za določanje interakcij
protein-protein
Spreminjanje genov - in vitro mutageneza, živalski
modeli z izbitim genom-pomen v funkcijski
genomiki in bolezenskih modelih
Preprečevanje izražanja genov - protismiselna
tehnologija, siRNA
Kloniranje človeških genov, reproduktivno
kloniranje sesalcev, terapevtsko kloniranje
Transgene rastline in živali
Genska tehnologija pri proizvodnji zdravil in
diagnostičnih sredstev
Zakonodaja in varnostni predpisi za delo z genetsko
spremenjenimi organizmi
Vloga rekombinantne DNA tehnologije v sodobni
družba: etični, sociološki in ekonomski vidiki
Laboratorijske vaje:
 Priprava genomskih in cDNA knjižnic
 Kloniranje: Gostiteljski organizmi, vektorji,
strategije kloniranja v prokariontske in
evkariontske orgnizme, transformacija in
transfekcija, ekspresija rekombinantnih
proteinov
 Preiskava DNA za tipizacijo tkiv in za osebno
identifikacijo
Gene therapy
Ethics in genomics
Hybridization of nucleic acids, DNA micro arrays
Polymerase DNA reaction (PCR), DNA sequencing
Yeast two-hybrid system for identification of
protein-protein interaction
Site directed mutagenesis, knock-out technology
and animal models-the role in functional genomics
and animal disease models
Silencing gene expression: RNAi, antisense RNA
technology
Cloning human genes, reproductive cloning of
mammalians, therapeutic cloning
Transgenic plants and animals
Gene technology in drug production and diagnostics
Low regulations and safety precautions for research
and applications of genetic modified organisms
Recombinant DNA technology and society: ethic and
social economic issues
Laboratory work:
 preparation of genomic and cDNA libraries
 Cloning: Host organisms, DNA cloning vectors,
cloning strategy in eukaryotes and
prokaryotes, transformation and transfect ion,
expression of recombinant proteins
 DNA fingerprinting in forensics
Temeljni literatura in viri / Textbooks:
 Thompson & Thompson: Genetics in Medicine, W.B.Saunders Company., 7the ISBN 0-7216-0244-4 and
7th ed. ISBN: 9781416030805, 2007.
 Tom Strachan, Judith Goodship & Patrick Chinnery, Genetics and genomics in medicine, Garland Sc,
ISBN 9780815344803, 2014.
Dodatna priporočena literatura:
 Bernard R. Glick, Jack J. Pasternak: Principles and applications of recombinant DNA, 3rd edition, ASM
Press, Washington, 2003.
 Philip Benfey: Genomics, Prentice Hall, Inc., New Jersey , 2005.
Cilji in kompetence:
Študenti bodo spoznali osnovne tehnike in uporabo
rekombinantne DNA tehnologije v raziskavah in v
praksi.
Objectives and competences:
Students will be provided with basic techniques and
applications of recombinant DNA technology in
research and industry.
Predvideni študijski rezultati:
Znanje in razumevanje:
 tehnike in principi kloniranja DNA in ostalih
pristopov v rekombinanti DNA tehnologiji
 uporaba rekombinantne DNA tehnologije v
raziskavah in praksi
Prenesljive/ključne spretnosti in drugi atributi:
Intended learning outcomes:
Knowledge and Understanding:
 techiques and principles of DNA cloning and
other recombinant DNA technology
 applications of recombinant DNA technology in
research and industry
Transferable/Key Skills and other attributes:
46
Metode poučevanja in učenja:
 Predavanja
 Seminarske vaje
 Laboratorijske vaje
Načini ocenjevanja:
Izpit je opravljen, če so pozitivno
opravljene vse naslednje obveznosti:
 pisni izpit
 ustni izpit
Learning and teaching methods:
 Lectures
 Tutorial
 Laboratory work
Delež (v %) /
Weight (in %)
60
40
Assessment:
Student has to pass successfully the
following obligations:
 writen examination
 oral examination
Reference nosilca / Lecturer’s references:
JOSTINS, Luke, MITROVIČ, Mitja, POTOČNIK, Uroš. Host-microbe interactions have shaped the genetic architecture
of inflammatorybowel disease. Nature (Lond.), 2012, vol. 491, no. 7422, str. 119-124, doi: 10.1038/nature11582.
[COBISS.SI-ID 512230968],
LIU, Jimmy Z, MITROVIČ, Mitja, POTOČNIK, Uroš. Dense genotyping of immune-related disease regions identifies
nine new risk loci for primary sclerosing cholangitis. Nat Genet, 2013, 79 str., ilustr.
http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.2616.html, doi: 10.1038/ng.2616. [COBISS.SI-ID
512280376],
RIVAS, Manuel A, MITROVIČ, Mitja, POTOČNIK, Uroš. Deep resequencing of GWAS loci identifies independent rare
variants associated with inflammatory bowel disease. Nat Genet, 2011, vol. 43, no. 11, str. 1066-1073, doi:
10.1038/ng.952. [COBISS.SI-ID 15421974],
ALMOUZNI, Geneviève, GRGUREVIČ, Neža, MAJDIČ, Gregor, POTOČNIK, Uroš, ILAŠ, Janez, et al. Relationship
between genome and epigenome - challenges and requirements for future research. BMC genomics, ISSN 14712164, 2014, vol. 15, no. 487, str. 1-7. http://www.biomedcentral.com/1471-2164/15/487, doi: 10.1186/14712164-15-487. [COBISS.SI-ID 512412216],
REPNIK, Katja, POTOČNIK, Uroš. Haplotype in the IBD5 region is associated with refractory Crohn's disease in
Slovenian patients and modulates expression of the SLC22A5 gene. J Gastroenterol, 2011, vol. 46, no. 9, str. 10811091, doi: 10.1007/s00535-011-0426-6. [COBISS.SI-ID 15110422].
47
Okoljska biotehnologija
Predmet:
Course title:
UČNI NAČRT PREDMETA / COURSE SYLLABUS
Okoljska biotehnologija
Environmental Biotechnology
Študijski program in stopnja
Study programme and level
Letnik
Academic
year
Študijska smer
Study field
Kemijska tehnika / 2. stopnja
Chemical Engineering / 2nd level
2.
Vrsta predmeta / Course type:
Semester
Semester
zimski
Autumn
Izbirni / Elective
Univerzitetna koda predmeta / University course code:
Predavanja
Lectures
15
Seminar
Seminar
Nosilec predmeta / Lecturer:
Jeziki /
Languages:
Sem. vaje
Tutorial
Lab. vaje
Labor work
15
Teren. vaje
Field work
Samost. delo
Individ. work
150
ECTS
6
Maja Leitgeb
Predavanja / Lecture: slovenski / Slovene
Vaje / Tutorial: slovenski / Slovene
Pogoji za vključitev v delo oz. za opravljanje
študijskih obveznosti:
Prerequisites:
Potrebno je znanje iz mikrobiologije, biokemije,
industrijske mikrobiologije in separacijske tehnike.
Knowledge of microbiology, biochemistry, industrial
microbiology and separation processes is needed.
Vsebina:
Odpadne vode (komunalne, industrijske, lastnosti).
Čiščenje odpadnih vod z aerobnimi procesi (cilji in
omejitve, vrste procesov).
Čiščenje odplak z anaerobnimi procesi (biologija
formiranja metana, vrste procesov, procesni
pogoji).
Biološko čiščenje odpadnega zraka in razgradnja
trdnih odpadkov.
Vzorčevanje, priprava vzorcev, ekstrakcija celic,
detekcija funkcionalnih aktivnosti v vzorcih iz
okolja.
Bioremediacija.
Kompostiranje.
Bioinsekticidi.
Content (Syllabus outline):
Wastewater (communal sewage, industrial
effluents, properties of the substrate wastewater).
Purification of wastewater by aerobic processes
(aims and limitations, purification processes).
Purification of effluents by anaerobic processes
(biology of formation of methane, technical
processes, process conditions).
Biological purification of waste air and degradation
of solid wastes.
Sampling, sample preparation, cell extraction,
detection of functional activity in environmental
samples.
Bioremediation.
Composting.
Bioinsecticides.
48
Laboratorijske vaje iz področja detekcije
funkcionalnih aktivnosti v vzorcih iz okolja.
Laboratory work from the field of detection of
functional activity in environmental samples.
Temeljni literatura in viri / Textbooks:
 G. M. Evans, J. C. Furlang, Environmental Biotechnology: Theory and Applications, 2nd ed., Wiley
Weinheim, 2010.
 R. H. Baltz, A. L. Demain, J. E. Davies, Manual of Industrial Microbiology and Biotechnology, 3 rd
ed., ASM Press, Washington, D.C., 2010.
Dodatna priporočena literatura:
 G. Lear, G. D. Lewis, Microbial Biofilms: Current Research and Applications, Caister Academic Press,
New Zealand, 2012.
Cilji in kompetence:
Uporaba bioloških snovi (organizmov ali njihovih
delov), skupaj s kemijskimi, fizikalnimi in
inženirskimi procesi, za zaščito in obnovo okolja.
Objectives and competences:
Application of biological agents (organisms or their
components), along with chemical, physical and
engineering processes to protect and restore the
environment.
Predvideni študijski rezultati:
Znanje in razumevanje:
Poznavanje vloge »tehnične mikrobiologije« pri
razvoju procesov čiščenja odpadnih vod in zraka ter
tehnologij z uporabo bioloških sistemov za katalizo
razpada ali transformacije raznih kemikalij v manj
škodljive oblike.
Intended learning outcomes:
Knowledge and Understanding:
Understanding of the role of »technical
microbiology« in the development of waste water
and air purification processes and technologies that
use biological systems to catalyze the destruction or
transformation of various chemicals to less harmful
forms.
Prenesljive/ključne spretnosti in drugi atributi:
Predmet se dopoljnjuje z ostalimi vsebinami smeri
Biokemijska tehnika.
Transferable/Key Skills and other attributes:
The subject is related to the other subjects on the
study field Biochemical engineering.
Metode poučevanja in učenja:
Predavanja v učilnici, ki je opremljena z avdiovizualnimi pripomočki.
Individualna priprava seminarskih nalog s
predstavitvijo in diskusijo.
Laboratorijsko delo na izbranem primeru.
Learning and teaching methods:
Lectures in a lecture room, equipped with audiovisual equipment
Individual preparation of seminars and their
presentation with discussion.
Laboratory work on a selected case.
Načini ocenjevanja:
Izpit je opravljen, če so pozitivno
opravljene vse naslednje obveznosti:
- laboratorijske vaje
- ustni izpit
Delež (v %) /
Weight (in %)
30
70
49
Assessment:
Student has to pass successfully the
following obligations:
- laboratory work
- oral examination
Reference nosilca / Lecturer’s references:
LEITGEB, Maja, ČOLNIK, Maja, PRIMOŽIČ, Mateja, ZALAR, Polona, GUNDE-CIMERMAN, Nina, KNEZ, Željko. Activity
of cellulase and [alpha]-amylase from Hortaea werneckii after cell treatment with supercritical carbon dioxide. The
Journal of supercritical fluids, ISSN 0896-8446. 2013, 78, 143-148, doi: 10.1016/j.supflu.2013.03.029. [COBISS.SIID 16864790]
ČOLNIK, Maja, PRIMOŽIČ, Mateja, KNEZ, Željko, LEITGEB, Maja. Use of supercritical carbon dioxide for proteins and
alcohol dehydrogenase release from yeast Saccharomyces cerevisiae. The Journal of supercritical fluids, ISSN 08968446. 2012, 65, 11-17, doi: 10.1016/j.supflu.2012.02.018. [COBISS.SI-ID 15901462]
KAVČIČ, Sabina, KNEZ, Željko, LEITGEB, Maja. Antimicrobial activity of n-butyl lactate obtained via enzymatic
esterification of lactic acid with n-butanol in supercritical trifluoromethane. The Journal of supercritical fluids, ISSN
0896-8446. 2014, 85, 143-150, doi: 10.1016/j.supflu.2013.11.003. [COBISS.SI-ID 17392406]
THOREY, Paul, KNEZ, Željko, LEITGEB, Maja. Alcohol dehydrogenase in non-aqueous media using high-pressure
technologies : reaction set-up and deactivation determination. Journal of chemical technology and biotechnology,
ISSN 0268-2575. 2010, 85, 1011-1016. [COBISS.SI-ID 14291222]
KNEZ, Željko, MARKOČIČ, Elena, LEITGEB, Maja, PRIMOŽIČ, Mateja, KNEZ HRNČIČ, Maša, ŠKERGET, Mojca.
Industrial applications of supercritical fluids : a review. Energy, ISSN 0360-5442. 2014, 1-9,
doi: 10.1016/j.energy.2014.07.044. [COBISS.SI-ID 18010134]
50
Priprava in čiščenje vod
Predmet:
Course title:
UČNI NAČRT PREDMETA / COURSE SYLLABUS
Priprava in čiščenje vod
Water Conditioning and Treatment
Študijski program in stopnja
Study programme and level
Kemijska tehnika / 2. stopnja
Chemical Engineering / 2nd level
Študijska smer
Study field
Kemijska tehnika
Chemical Engineering
Vrsta predmeta / Course type:
Letnik
Academic year
2.
Semester
Semester
zimski
Autumn
Izbirni / Elective
Univerzitetna koda predmeta / University course code:
Predavanja
Lectures
15
Seminar
Seminar
Nosilec predmeta / Lecturer:
Jeziki /
Languages:
Sem. vaje
Tutorial
Lab. vaje
Labor work
15
Teren. vaje
Field work
Samost. delo
Individ. work
150
ECTS
6
Marjana Simonič
Predavanja / Lecture: slovenski / Slovene
Vaje / Tutorial: slovenski / Slovene
Pogoji za vključitev v delo oz. za opravljanje
študijskih obveznosti:
Splošno znanje iz anorganske in analizne kemije
Prerequisites:
Vsebina:
 Kemijska sestava in lastnosti vod:
- pitnih
- odpadnih
 Evropska zakonodaja
 Glavni onesnaževalci vod: težke kovine,
pesticidi, PCB, motilci endokrinega sistema,
antibiotiki
 Mehansko in kemijsko čiščenje pitnih vod
 Čiščenje komunalne odpadne vode (primarno,
sekundarno, terciarno čiščenje)
 Čiščenje industrijske odpadne vode
 Napredni postopki čiščenja z membranami in
ozonom z različnimi kombinacijami (UV, H2O2,
katalizatorji)
Content (Syllabus outline):
 Chemical Water Characteristics
- drinking water
- wastewater
 European Legislation
 Main Water Pollutants: heavy metals,
pesticides, PCB, endocrine disruptors,
antibiotics
 Mechanical and Chemical drinking water
treatment
 Municipal wastewater treatment (primary,
secondary, tertiary treatment)
 Industrial wastewater treatment
 Advanced water treatment: membrane or using
ozone in combination with UV irradiation, H2O2,
catalysts
Seminar work:
Students independently solve problems in the field
of the municipal or industrial wastewater treatment
and discuss the solutions.
Seminarska naloga:
študentje samostojno obdelajo določen problem s
področja čiščenja komunalnih in industrijskih
odpadnih vod.
General knowledge of Inorganic and Analytical
Chemistry
51
Temeljni literatura in viri / Textbooks:
 Roš M., Simonič M., Šostar-Turk S., Priprava in čiščenje vod, Maribor: Fakulteta za strojništvo (Tiskarna
tehniških fakultet), 2005.
Dodatna priporočena literatura:
 Manahan S.E., Environmental Chemistry, 8th edition, CRC Press USA, 2005.
 Wastewater Engineering, Treatment and Reuse, 4th edition. Mc Graw Hill Co, 2003.
Cilji in kompetence:
Spoznati pomembnost priprave vod
Spoznati fizikalno-kemijske tehnike priprave in
čiščenja vod
Osvojiti napredne tehnike čiščenja
Sposobnost predlagati najprimernejšo tehnologijo
čiščenja
Sposobnost izboljšanja obstoječih tehnologij
čiščenja vod
Sposobnost preliminarnega načrtovanja naprav
Objectives and competences:
To acquaint with water conditioning
Understanding the physico-chemical techniques of
water conditioning and treatment
To acquaint advanced techniques of water
treatment
Ability to propose the solution for the best water
treatment method
Understanding of how to improve the existing
technologies for water treatment
Ability to design the treatment plants
Predvideni študijski rezultati:
Razumevanje priprave vod
Razumevanje fizikalno-kemijskih tehnik čiščenja
vod
Napredne tehnike čiščenja
Sposobnost predlagati najprimernejšo tehnologijo
čiščenja
Sposobnost izboljšanja obstoječih tehnologij
čiščenja vod
Intended learning outcomes:
Understanding of water treatment
Understanding the physico-chemical techniques of
water treatment
Advanced techniques of water treatment
Ability to propose the solution for the best water
treatment method
Ability to improve the existing technologies for
water treatment
Prenesljive/ključne spretnosti in drugi atributi:
- osvojiti znanje za dobro delo v praksi
- pripraviti pisna poročila in drugo dokumentacijo,
- pisno in ustno komunicirati o problematiki.
Transferable/Key Skills and other attributes:
- achieving knowledge for good praxtice in
industry,
- prepare written reports
- discuss the problem.
Metode poučevanja in učenja:
predavanja,
seminarska naloga,
ustni zagovor
Learning and teaching methods:
Lectures,
Seminar work,
Oral examinations
Načini ocenjevanja:
Izpit je opravljen, če so pozitivno
opravljene vse naslednje obveznosti:
 ustni izpit
 seminarska naloga
 aktivno delo na predavanjih
Delež (v %) /
Weight (in %)
60
30
10
52
Assessment:
Student has to pass successfully the
following obligations:
 oral examination
 seminar work
 active work during lectures
Reference nosilca / Lecturer’s references:
TEPUŠ, Brigita, SIMONIČ, Marjana, PETRINIĆ, Irena. Comparison between nitrate and pesticide removal from
ground water using adsorbents and NF and RO membranes. Journal of hazardous materials, ISSN 0304-3894. [Print
ed.], 2009, vol. 170, iss. 2/3, str. 1210-1217.
PETROVIČ, Aleksandra, SIMONIČ, Marjana. The efficiency of a membrane bioreactor in drinking water
denitrification. Chemical industry & chemical engineering quarterly, ISSN 1451-9372, Online first 2014, vol. , no ,
str. 1-17.
KRIŽAN, Janja, MURIĆ, Arnela, PETRINIĆ, Irena, SIMONIČ, Marjana. Recent developments in membrane treatment
of spent cutting-oils: a review. Industrial & engineering chemistry research, ISSN 0888-5885. [Print ed.], 2013, vol.
52, no. 23, str. 7603-7616.
KRIŽAN, Janja, PETRINIĆ, Irena, GORŠEK, Andreja, SIMONIČ, Marjana. Ultrafiltration of oil-in-water emulsion by
using ceramic membrane : Taguchi experimental design approach. Central European Journal of Chemistry, ISSN
1895-1066, Feb. 2014, vol. 12, iss. 2, str. 242-249.
53
Nutracevtiki
Predmet:
Course title:
UČNI NAČRT PREDMETA / COURSE SYLLABUS
Nutracevtiki
Nutraceuticals
Študijski program in stopnja
Study programme and level
Študijska smer
Study field
Letnik
Academic year
Semester
Semester
2.
zimski
Autumn
Kemijska tehnika / 2. stopnja
Chemical Engineering / 2nd level
Vrsta predmeta / Course type:
Izbirni / Elective
Univerzitetna koda predmeta / University course code:
Predavanja
Lectures
15
Seminar
Seminar
Nosilec predmeta / Lecturer:
Jeziki /
Languages:
Sem. vaje
Tutorial
Lab. vaje
Labor work
15
Teren. vaje
Field work
Samost. delo
Individ. work
150
ECTS
6
Mojca Škerget
Predavanja / Lecture: slovenski / Slovene
Vaje / Tutorial: slovenski / Slovene
Pogoji za vključitev v delo oz. za opravljanje
študijskih obveznosti:
Pogojev ni.
Prerequisites:
Vsebina:
 prosti radikali in vloga antioksidantov v
bioloških sistemih.
 identifikacija
naravnih
spojin
z
antioksidativnim,
antimikotičnim
ali
farmakološkim učinkom: vitamini, karotenoidi,
n-3 poli nenasičene maščobne kisline, fenolne
spojine, lipojska kislina, terpenoidi, steroidi,
alkaloidi,...
 naravni viri ter postopki izolacije in
koncentriranja
učinkovin:
ekstrakcija,
kromatografija,...
 vpliv učinkovine na zdravje ter na pojav
boleznini in možnosti zdravljenja.
 metode določanja antioksidacijskega
potenciala: in vitro testiranja (Rancimat test,
peroksidno število, anizidinsko število, metoda
s standardom TROLOX, BCB test (beta-carotene
bleaching test), ORAC test (oxygen radical
absorbance capacity), DPPH test (free radical
Content (Syllabus outline):
 Free radicals and the role of antioxidants in
biological systems;
 identification of substances with antioxidative,
antimicotic
or
pharmacological
activity
(vitamins, carotenoids, n-3 polyunsaturated
fatty acids, phenolic compounds, Lipoic acid,
terpenoids, steroids, alkaloids,...);
 natural sources and isolation and concentration
methods (extraction, chromatography,…);
 influence of substances on health and
occurrence of sickness, disease prevention;
 methods for testing antioxidative activity: in
vitro tests (Rancimat test,peroxide value,
anisidine value, method with the standard
TROLOX, BCB test (beta-carotene bleaching
test), ORAC test (oxygen radical absorbance
capacity), DPPH test (free radical scavenging
capacity), test with the radical DMPD,
determining the inhibition of human LDL,…),
None.
54
scavening capacity), test s pomočjo radikala
DMPD, določanje inhibicije oksidacije
človeškega LDL, ....), biomarkerji oksidativnega
stresa in vivo.
Vaje:
laboratorijsko delo na izbranem primeru, uporaba
tehnik za izolacijo in koncentriranje nutracevtika in
testiranja aktivnosti in vitro.
oxidative stress biomarkers in vivo.
Labor work:
laboratory work on selected case, isolation and
concentration of nutraceuticals, in vitro activity
tests.
Temeljni literatura in viri / Textbooks:
 Handbook of Nutraceuticals and Functional Foods, R. E. C. WILDMAN (Ed.), 2nd Ed., CRC Press, Taylor &
Francis Group, Boca Raton 2007.
 K. Kramer, P.-P. Hoppe, L. Packer, eds., Nutraceuticals in Health and Disease Prevention. Marcel Dekker,
Inc. New York, 2001.
Dodatna priporočena literatura:
 D. Armstrong, ed., Oxidative Stress Biomarkers and Antioxidant Protocols. Humana Press Inc., New
Jersey, 2002.
 J. Buttriss, M. Saltmarsh, eds., Functional foods II: claims and evidence, Cambridge: Royal Society of
Chemistry, 2000.
 E. Cadenas, L. Packer, Handbook of Antioxidants, 2nd ed., Marcel Dekker, Inc. New York, 2002.
Cilji in kompetence:
Spoznati naravne produkte, ki pozitivno vplivajo na
človeško zdravje (nutracevtiki), metode njihove
izolacije, področja uporabe, kot tudi njihove vplive
na zdravje in testne metode.
Objectives and competences:
To recognize natural products, which have positive
influence on human health (nutraceuticals), the
isolation methods, possible areas of application, as
well as their influence on the health and test
methods.
Predvideni študijski rezultati:
Znanje in razumevanje:
 Vrst, virov, metod pridobivanja, lastnosti in
delovanje naravnih bioaktivnih komponent z
antioksidativnim, antimikrobiološkim in
farmakološkim učinkom za uporabo v
prehrambni, kozmetični, predvsem pa v
farmacevtski oziroma fitofarmacevtski industriji;
 In vitro in in vivo analiznih metod za testiranje
antioksidacijskega potenciala
Intended learning outcomes:
 Knowledge and Understanding:
 Types, sources, separation methods, properties
and activity of natural bioactive compounds with
antioxidative, antimicrobiological and
pharmacological activity for the use in food,
cosmetic and especially in pharmaceutical or
phytopharmaceutical industry;
 In vitro and in vivo analytical methods for testing
antioxidative potential.
Prenesljive/ključne spretnosti in drugi atributi:
 znanja za inovativno delo v prehrambni,
kozmetični, predvsem pa v farmacevtski oziroma
fitofarmacevtski industriji.
Transferable/Key Skills and other attributes:
 Achieving knowledge for inovative work in food,
cosmetic and especially in pharmaceutical or
phytopharmaceutical industry.
Metode poučevanja in učenja:
 Predavanja,
 Laboratorijsko delo na izbranem primeru.
Learning and teaching methods:
 Lectures,
 Laboratory work on selected case.
55
Načini ocenjevanja:
Izpit je opravljen, če so pozitivno
opravljene vse naslednje obveznosti:
 ustni izpit
 projektno poročilo
Delež (v %) /
Weight (in %)
50
50
Assessment:
Student has to pass successfully the
following obligations:
 Oral examination
 Project report
Reference nosilca / Lecturer’s references:
OMAN, Miha, ŠKERGET, Mojca, KNEZ, Željko. Application of supercritical fluid extraction for the separation of
nutraceuticals and other phytochemicals from plant material. Macedonian journal of chemistry and chemical
engineering, ISSN 1857-5552, 2013, vol. 32, no. 2, str. 183-226. [COBISS.SI-ID 17365014]
ĐILAS, Sonja, KNEZ, Željko, ČETOJEVIĆ-SIMIN, Dragana, TUMBAS, Vesna, ŠKERGET, Mojca, ČANADOVIĆ-BRUNET,
Jasna, CETKOVIC, Gordana. In vitro antioxidant and antiproliferative activity of three rosemary (Rosmarinus
officinalis L.) extract formulations. International journal of food science & technology, ISSN 0950-5423. [Print ed.],
2012, vol. 47, iss. 10, str. 2052-2062, doi: 10.1111/j.1365-2621.2012.03069.x. [COBISS.SI-ID 16125206],
RUŽIĆ, Iva, ŠKERGET, Mojca, KNEZ, Željko. Potential of phenolic antioxidants. Acta chimica slovenica, ISSN 13180207. [Tiskana izd.], 2010, vol 57, no. 2, str. 263-271. [COBISS.SI-ID 14214678].
RAVBER, Matej, KNEZ, Željko, ŠKERGET, Mojca. Simultaneous extraction of oil- and water-soluble phase from
sunflower seeds with subcritical water. Food chemistry, 2015, vol. 166, str. 316-323. [COBISS.SI-ID 17908502].
ŠKERGET, Mojca. Separacija in koncentriranje naravnih učinkovin : znanstveno tehnološko sodelovanje z Republiko
Madžarsko, 2008-2009 = Separation and concentration of active compounds : Slovenia-Hungary cooperation in
science and technology, 2008-2009. Maribor: Fakulteta za kemijo in kemijsko tehnologijo; Budapest: Corvinus
University of Budapest, Department of food Engineering, 2010. [5] f. [COBISS.SI-ID 15903254]
ŠKERGET, Mojca, MAJHENIČ, Lucija, BEZJAK, Miran, KNEZ, Željko. Antioxidant, Radical Scavenging and Antimicrobial
Activities of Red Onion (Allium cepa L) Skin and Edible Part Extracts. Chemical and biochemical engineering
quarterly, ISSN 0352-9568, 2009, vol. 23, no. 4, str. 435-444, ilustr. [COBISS.SI-ID 13799190]
56
Management inoviranja
Predmet:
Course title:
UČNI NAČRT PREDMETA / COURSE SYLLABUS
Management inoviranja
Innovation Management
Študijski program in stopnja
Study programme and level
Študijska smer
Study field
Letnik
Academic year
Kemijska tehnika / 2. stopnja
Chemical Engineering / 2nd level
2.
Vrsta predmeta / Course type:
Semester
Semester
zimski
Autumn
Izbirni / Elective
Univerzitetna koda predmeta / University course code:
Predavanja
Lectures
15
Seminar
Seminar
Nosilec predmeta / Lecturer:
Jeziki:
Languages:
Sem. vaje
Tutorial
Lab. vaje
Labor work
15
Teren. vaje
Field work
Samost. delo
Individ. work
150
ECTS
6
Dušan Klinar
Predavanja / Lecture: slovensko / Slovene
Vaje / Tutorial: slovensko / Slovene
Pogoji za vključitev v delo oz. za opravljanje
študijskih obveznosti:
Pogojev ni.
Prerequisites:
Vsebina:
- Osnove inoviranja in inovacij
- Povezave sistema inoviranja in sistema
kakovosti
- Stategije in inoviranje
- Potreba po raziskovanju in razvoju (RiR)
- Management RiR (organiziranje, izvajanje,
nadzor in metrika)
- Storitve in RiR
- Etična vprašanja RiR
- Odnosi RiR z zunanjim in notranjim okoljem
- Izhodišča, pomen, in umestitev razvoja novih
produktov (RNP)
- Pregled razvoja zamisli o RNP
- Modeli in procesi RNP
- Management RNP
Content (Syllabus outline):
- Fundamentals and theory of Innovation
- Relationship among Innovation and quality
systems
- Strategy and Innnovation
- Why Research and Development (R&D)
- Management of R&D (organization,
implementation, controling and metrics)
- Service R&D
- Ethical considerations of R&D
- Integration R&D in environment and
organization
- Basics of the New Product Development (NPD)
process
- Idea generation for NPD
- Concepts and processes of the NPD
- NPD Management
Seminarske vaje:
- Obravnava primera dobre prakse
- Analiza primera in primerjave
None.
Tutorial:
- Cases of good practise
57
- Program RNP
- Case analysis and bench marking
- NPD project
Temeljni literatura in viri / Textbooks:
 Borut Likar, O inovativnosti slovenske predelovalne in izbranih storitvenih dejavnosti, Univerza na
Primorskem, Fakulteta za management Koper, 2014, izbrana poglavja.
 Peter Fatur, Borut Likar, Ustvarjalnost zaposlenih za inovativnost podjetja: sistemski vidiki
managementa idej kot gradnika uspešne organizacije, Univerza na Primorskem, Fakulteta za
management Koper, 2009, izbrana poglavja.
Dodatna priporočena literatura:
 Ettlie, J. E., Managing Innovation, Butterworth-Heinemann, 2006.
 Ettlie, J. E., Managing Technological Innovation, John Wiley & Sons, 2000.
 Rainey, D. L., Sustainable Business Development Inventing the Future Through Strategy, Innovation,
and Leadership, Cambridge University Press, 2010.
 Cooper, R.G., Winning at New Products: Creating Value Through Innovation, Basic Books, 2011.
Cilji in kompetence:
Spoznati vsebino in pomen:
 managementa inoviranja in inovacij
 inoviranja in strateškega planiranja v podjetju
 inoviranja in sistema kakovosti v podjetju
 vloge RiR v podjetju
 principov vodenja in upravljanja RiR
 izhodišč, pomena in umestitve RNP
 izvedbenega procesa RNP
Objectives and competences:
To acquaint the content and meaning:
 innovation management
 innovations and strategic planning
 innovations and quality management
 R&D in business unit
 management R&D
 NPD processes
 process of the implementation NPD
Predvideni študijski rezultati:
Znanje in razumevanje:
- pomena in vsebine inoviranja, inovacijskih
procesov v podjetju in nacionalni ekonomiji
- vodenja in upravljanja RiR
- pomena managementa RNP
Prenesljive/ključne spretnosti in drugi atributi:
- razumevanje inovacijske verige in pomena
managementa pri svojem delu
- zavedanje pomena RiR v podjetju
- zavedanje pomena RNP
Intended learning outcomes:
Knowledge and Understanding:
- of the meaning of innovation, principles and
processes within the company and within
national economy
- management of the R&D
- the importance of NPD management
Transferable/Key Skills and other attributes:
- to understand innovation chain and innovation
management
- to understand meaning of RiR in the company
- to understand meaning of the NPD proces
Metode poučevanja in učenja:
- predavanja
- multimedijske predstavitve
- obravnave primerov
- obravnava aktualnega stanja inoviranja v
državi
- delo na internetu
- seminarske vaje
- priprava elaborata
Learning and teaching methods:
- lectures
- multimedia presentations
- case studies
- discussion about the actual national innovation
system
- online www search
- seminar training
- preparation of the expert's detail report
Načini ocenjevanja:
Izpit je opravljen, če so pozitivno
opravljene vse naslednje obveznosti:
- predstavitev projekta
Delež (v %) /
Weight (in %)
60
58
Assessment:
Student has to pass successfully the
following obligations:
- project presentation
- projektno delo
- ustni izpit
20
20
- project work
- oral examination
Reference nosilca / Lecturer’s references:
NAROBE, Miha, GOLOB, Janvit, KLINAR, Dušan, FRANCETIČ, Vojmir, LIKOZAR, Blaž. Co-gasification of biomass and
plastics: pyrolysis kinetics studies, experiments on 100 kW dual fluidized bed pilot plant and development of
thermodynamic equilibrium model and balances. Bioresource technology, ISSN 0960-8524. [Print ed.], Jun. 2014,
vol. 162, str. 21-29. http://www.sciencedirect.com/science/article/pii/S096085241400426X,
doi: 10.1016/j.biortech.2014.03.121. [COBISS.SI-ID 5457690]
LAH, Branko, KLINAR, Dušan, LIKOZAR, Blaž. Modeling, optimization and scale-up of waste tire pyrolysis. V: 6th
Dubrovnik Conference on Sustainable Development of Energy, Water and Environment Systems, September 25 October 29, 2011, Dubrovnik, Croatia. Conference proceedings. [S. l.: s. n.], 2011, str. [1-15], ilustr. [COBISS.SIID 4837146]
KLINAR, Dušan, BRENCELJ, Albin. Metoda za ciklično vakumiranje v šaržnem reaktorju : patent št. SI 23545 A,
datum objave 31. 05. 2012; patentna prijava št. P-201000369 z dne 09. 11. 2010. Ljubljana: Urad RS za
intelektualno lastnino, 2012. [5] str. [COBISS.SI-ID 16117782]
KLINAR, Dušan. Doseganje učinkovitosti rabe virov s kombiniranjem snovne in energetske izrabe = Resource
efficiency by combination of material and energy recovery path. V: Strokovno posvetovanje 2014 Gospodarno in
odgovorno!, Moravske Toplice, Hotel Ajda, 20. in 21. marec 2014. Ljubljana: Zveza ekoloških gibanj Slovenije, 2014,
str. 115-121, ilustr. [COBISS.SI-ID 17909014]
HARB, Darja, SELINŠEK, Zdenka, KLINAR, Dušan, PETEK, Janez. Okoljska ekonomika in podjetništvo : sestavina
študijskega programa. [Ljubljana: CPI, 2011].
http://www.cpi.si/files/cpi/userfiles/Datoteke/kurikulum/Programoteka/PROGVIS/Bionika/Bionika_2011_P10_Bionska_ekonomika_in_podjetni%C5%A1tvo.doc [COBISS.SI-ID 356479]
59
Čistejša proizvodnja
Predmet:
Course title:
UČNI NAČRT PREDMETA / COURSE SYLLABUS
Čistejša proizvodnja
Cleaner Production
Študijski program in stopnja
Study programme and level
Kemijska tehnika / 2. stopnja
Chemical Engineering / 2nd level
Študijska smer
Study field
Kemijska tehnika
Chemical Engineering
Vrsta predmeta / Course type:
Letnik
Academic year
2.
Semester
Semester
zimski
Autumn
Izbirni / Elective
Univerzitetna koda predmeta / University course code:
Predavanja
Lectures
15
Seminar
Seminar
Nosilec predmeta / Lecturer:
Jeziki /
Languages:
Sem. vaje
Tutorial
15
Lab. vaje
Labor work
Teren. vaje
Field work
Samost. delo
Individ. work
150
ECTS
6
Zorka Novak Pintarič
Predavanja / Lecture: slovenski / Slovene
Vaje / Tutorial: slovenski / Slovene
Pogoji za vključitev v delo oz. za opravljanje
študijskih obveznosti:
Načrtovanje procesov
Razvoj produktov in procesov
Prerequisites:
Vsebina:
Zgodovinski razvoj od ‘end-of-pipe’ tehnologij do
preprečevanja onesnaževanja.
Hierarhija čistejše proizvodnje (preprečevanje v
fazi načrtovanja, zmanjševanje na viru, obtakanje,
obdelava, uničevanje, odlaganje).
Izbor surovin, katalizatorjev, topil, reakcijskih poti.
Osnovne operacije in čistejša proizvodnja (kemijski
reaktorji, separacija, obtakanje, obratovanje,
pogonski sistemi).
Energetska in snovna integracija za čistejšo
proizvodnjo.
Metodologija za vključitev načel čistejše
proizvodnje v načrtovanje in sintezo procesov.
Okoljsko tveganje procesov (modeliranje izpustov v
okolju, reakcije razgradnje v okolju, kvantitativna
metrika).
Content (Syllabus outline):
The historical development from end-of-pipe to
pollution prevention.
Cleaner production hierarchy (prevention during the
design, source reduction, recycling, treatment and
disposal).
Selection of feedstocks, catalysts, solvents, reaction
pathways.
Unit operations and cleaner production (chemical
reactors, separation, recycling, process operation,
utility systems)
Energy and mass integration for cleaner production.
Methodology for improving environmental
performance during process design and synthesis.
Environmental risk assessment (model approach for
determining fate and transport of chemical releases
into the environment, reaction loss processes,
metrics for environmental risk evaluation).
Seminarske vaje: načrtovanje trajnostnih procesov
Seminar work: sustainable design of processes and
Process Design
Product and Process Development
60
in produktov s praktičnimi primeri (priprava na
projekt, analiza stanja, iskanje idej za izboljšanje,
razvoj konceptov, okoljski vplivi, akcijski načrt in
ocenjevanje), priprava pisne seminarske naloge.
products with case studies (preparation of an
ecodesign project, assessment phase, generation of
alternatives, developing concepts, environmental
aspects, action plan and evaluation), preparation of
written report.
Temeljni literatura in viri / Textbooks:
 El-Halwagi M. M. Sustainable Design Through Process Integration (poglavja 1, 4, 5). Elsevier, Oxford,
2012.
 Klemeš J., Friedler F., Bulatov I., Varbanov P. Sustainability in the Process Industry, Integration and
Optimization (poglavji 4, 10), McGraw Hill, 2011.
 Smith R., Chemical Process Design and Integration (poglavje 28), J. Wiley, 2005.
 Schefflan R., Teach Yourself the Basics of Aspen Plus (poglavji 11, 14), AIChE, Wiley, 2011.
Dodatna priporočena literatura:
 Mulholland K. L. Identification of Cleaner Production Improvement Opportunities. John Wiley & Sons,
New Jersey, 2006.
 Azapagić A. Perdan S., Clift R. Sustainable development in practice. John Wiley & Sons, Chichester,
2004.
 Allen D. T., Ahonnard D. R. Green Engineering – Environmentally Conscious Design of Chemical
Processes. Prentice Hall, Upper Saddle River, 2002.
Cilji in kompetence:
Razumevanje kompleksnejših metodologij in
metod čistejše proizvodnje v procesih, storitvah,
razumevanje nastajanja vplivov na okolje v vseh
fazah življenjskega kroga, razviti celovit pogled na
okoljski vpliv proizvoda v vseh fazah življenjskega
kroga proizvoda in načini znižanja teh vplivov na
obstoječih ali proizvodih v načrtovalni fazi.
Objectives and competences:
Understanding complex cleaner production
methodologies and techniques of the production
processes and services. Understanding
environmental impacts of the entire life cycle of
products, knowing possibilities of the decreasing the
environmental impacts of existing and new products
during the design phase.
Predvideni študijski rezultati:
Znanje in razumevanje:
Študent mora biti sposoben samostojno izvesti
projekt čistejše proizvodnje v poljubnem
proizvodnem procesu, ovrednotiti okoljske vplive
skozi celotni življenjski krog, okoljsko primerjati in
določiti kriterije odločanja med več istovrstnimi
produkti ter poznati in razumeti osnove
metodologije okoljskega načrtovanja proizvoda
vključno z analizo in izboljšanjem poljubnega
proizvoda.
Intended learning outcomes:
Knowledge and Understanding:
A student should be able to implement CP project in
production process, assess environmental aspects of
the entire life cycle of a product and to define
environmental criteria for the decision making
between products. He/she has to understand basic
methodology of eco-design and carry out the
analysis and improvement options of a product.
Prenesljive/ključne spretnosti in drugi atributi:
Celostni pristop k okoljski analizi procesov.
Uporaba tehnik in metodologij ČP, LCA in
okoljskega načrtovanja.
Metode poučevanja in učenja:
Predavanja z diskusijo, izdelava posamičnega ali
skupinskega seminarskega dela z uporabo ustrezne
programske opreme.
Transferable/Key Skills and other attributes:
Integral approach to the process analysis.
Application of the methodologies and techniques of
CP, LCA and Eco-design.
Learning and teaching methods:
Lecture with discussion of the practical problems,
carrying out the individual or team seminar work.
61
Načini ocenjevanja:
Izpit je opravljen, če so pozitivno
opravljene vse naslednje obveznosti:
- ustni izpit
- seminarska naloga
- predstavitev seminarske naloge
Delež (v %) /
Weight (in %)
30
50
20
Assessment:
Student has to pass successfully the
following obligations:
- oral examination
- seminar work
- presentation of seminar work
Reference nosilca / Lecturer’s references:
TOKOS, Hella, NOVAK-PINTARIČ, Zorka, YANG, Yongrong. Bi-objective optimization of a water network via
benchmarking. Journal of cleaner production, ISSN 0959-6526. [Print ed.], 2013, vol. 39, str. 168-179, doi:
10.1016/j.jclepro.2012.07.051. [COBISS.SI-ID 16240918]
KRAVANJA, Zdravko, NOVAK-PINTARIČ, Zorka, SIMONIČ, Marjana, ŠKOF, Gorazd. Optimizacija obstoječe in
načrtovanje nove naprave za čiščenja odpadnih oljnih emulzij : zaključno poročilo projekta. Maribor: Fakulteta za
kemijo in kemijsko tehnologijo, Laboratorij za procesno sistemsko tehniko in trajnostni razvoj, 2013. 53 str., ilustr.
[COBISS.SI-ID 17120534]
TOKOS, Hella, NOVAK-PINTARIČ, Zorka, KRAJNC, Damjan. An integrated sustainability performance assessment and
benchmarking of breweries. Clean technologies and environmental policy, ISSN 1618-954X, 2012, vol. 14, no. 2, str.
173-193, doi: 10.1007/s10098-011-0390-0. [COBISS.SI-ID 15021334]
KRAVANJA, Zdravko, ROPOTAR, Marcel, NOVAK-PINTARIČ, Zorka. Two-step multiobjective synthesis of sustainable
chemical processes. Theoretical foundations of chemical engineering, ISSN 0040-5795, 2012, vol. 46, no. 6, str. 689698. [COBISS.SI-ID 16434710]
TOKOS, Hella, NOVAK-PINTARIČ, Zorka. Development of a MINLP model for the optimization of a large industrial
water system. Optimization and engineering, ISSN 1389-4420, 2012, vol. 13, iss. 4, str. 625-662, doi:
10.1007/s11081-011-9162-2. [COBISS.SI-ID 15125014]
62
Mehanika fluidov II
Predmet:
Course title:
UČNI NAČRT PREDMETA / COURSE SYLLABUS
Mehanika fluidov II
Fluid Mechanics II
Študijski program in stopnja
Study programme and level
Študijska smer
Study field
Letnik
Academic year
Semester
Semester
Kemijska tehnika / 2. stopnja
Chemical Engineering / 2nd level
Kemijska tehnika
Chemical Engineering
2.
zimski
Autumn
Vrsta predmeta / Course type:
Izbirni / Elective
Univerzitetna koda predmeta / University course code:
Predavanja
Lectures
Seminar
Seminar
15
Lab. vaje
Laboratory
work
Teren. vaje
Field work
15
Nosilec predmeta / Lecturer:
Jeziki /
Languages:
Sem. vaje
Tutorial
Samost. delo
Individ. work
ECTS
150
6
Darko Goričanec
Predavanja / Lectures: slovenski / Slovene
Vaje / Tutorial: slovenski / Slovene
Pogoji za vključitev v delo oz. za opravljanje
študijskih obveznosti:
Osnovno znanje matematike.
Prerequisits:
Vsebina:
 Ne–Newtonove tekočine: razvrstitev,
napetosti in viskoznost v ceveh
 Pretok skozi nanešene plasti: karakteristike
plasti, izgube trenja, mehanska energijska
bilanca
 Pretok v fluidiziranih plasteh
 Padajoči delci v fluidu
 Dvofazni tok
 Vodni in plinski pretočni sistemi: faktor
istočastnosti, načrtovanje in dimenzioniranje,
optimizacija, namestitev črpalk, tranzientni
pojavi, izbira pretočnih poti.
 Seminarske vaje:
Vaje se navezujejo na tematiko predmeta
Content (Syllabus outline):
Basic knowledge of mathematics.
 Non – Newton fluids: classification of fluids,
shear stress and viscosity, flow in pipes
 Flow through packed beds: characterization of a
packed bed, frictional loss, and mechanical
energy balance.
 Flow in fluidized beds: the fluidized state,
frictional loss and pumping requirement to
fluidize a bed of solids, minimum fluidizing
velocity
 Solid particles falling through fluids
 Two phase flow
 Water and gas flow systems: factor of
simultaneity, design and dimensioning,
optimisation, location of pumps, transient
phenomena
 Tutorials will be based on chosen topic
regarding the theme of the subject.
Študent samostojno reši deset praktičnih primerov
63
Students individually solve ten practical examples.
Temeljni literatura in viri / Readings:
 Frank M. White, Fluid Mechanics 6th edition, McGraw Hill, 2008.
Dodatna priporočena literatura:
 James O. Wilkes: Fluid Mechanics for Chemical Engineers with Microfluids and CFD 2nd Edition,
Prentice Hall, 2005.
 Octave Levenspiel, Tracer Technology: Modeling the Flow of Fluids, Springer; 2012.
 Pijush K. Kundu, Ira M. Cohen: Fluid Mechanics, Second Edition, Academic Press, 2001.
 Joel H. Ferziger, Milovan Peric: Computational Methods for Fluid Dynamics, Springer Verlag, 2001.
Cilji in kompetence:
Osnovne informacije o vrstah, pomenu in
lastnostih vodnih in plinskih omrežij
Osvojiti postopke modeliranja sistemov
Objectives and competences:
Basic information about the types, meaning and the
characteristics of water and gas networks
Predvideni študijski rezultati:
Znanje in razumevanje:
• Slušatelji se seznanijo z nekaterimi temeljnimi in
praktičnimi znanji vezanimi na energetska
omrežja.
Intended learning outcomes:
Knowledge and Understanding:
• Of fundamental and practical knowledge
regarding energy networks
Transferable/Key Skills and other attributes:
• Using the theory to solve practical problems
Prenesljive/ključne spretnosti in drugi atributi:
• Prenos teorije na reševanje praktičnih primerov
Metode poučevanja in učenja:
Predavanja: študent spozna teoretične vsebine
predmeta.
Learning and teaching methods:
Lectures: the student gets acquainted with
theoretical content of the subject.
Seminarske vaje: študent utrdi teoretično znanje in
spozna aplikativne možnosti reševanja primerov iz
prakse, študent izdela krajšo študijo oziroma
projekt, ki se navezuje na tematiko predmeta.
Seminar: the student upgrades the theoretical
knowledge with practical experience, conducting a
short study or project regarding the thematic of the
subject.
Načini ocenjevanja:
Izpit je opravljen, če so pozitivno
opravljene vse naslednje obveznosti:
• seminarska naloga
• računski del izpita
• teoretični del izpita
Delež (v %) /
Weight (in %)
30
40
30
Teoretični in računski del tvorita celoto in se
preverjata hkrati.
Assessment:
Student has to pass successfully the
following obligations:
• individual paper
• calculation part of the exam
• theoretical part of the exam
The theoretical and the calculus part of exam are
performed simultaneously.
64
Reference nosilca / Lecturer’s references:
JOTANOVIĆ, Milovan, MIŠČEVIĆ, Mirko, KULČAR, Bojan, GORIČANEC, Darko. Optimal proportion of refrigerants in
single- stage high-temperature heat pump. International journal of systems applications, engineering &
development,
ISSN
2074-1308.
[Online
ed.],
2012,
vol.
6,
iss.
6,
str.
365-375.
http://www.naun.org/multimedia/UPress/saed/16-565.pdf. [COBISS.SI-ID 16535830]
KROPE, Jurij, GORIČANEC, Darko, DOBERŠEK, Danijela. Optimizacija lokacije deponije, tehnologije transporta in
doziranja komunalne biomase v sušilnik premoga TET : končno poročilo. Maribor: Fakulteta za kemijo in kemijsko
tehnologijo, 2012. 90 f., ilustr. [COBISS.SI-ID 16563222
DOBERŠEK, Danijela, GORIČANEC, Darko, KROPE, Jurij. Dryers for sewage sludge dehydration. International journal
of
energy
and
environment,
2012,
vol.
6,
iss.
6,
str.
588-596.
http://www.naun.org/multimedia/NAUN/energyenvironment/16-691.pdf. [COBISS.SI-ID 16535062]
ZORKO, Jerneja, GORIČANEC, Darko, KROPE, Jurij. Process of oxygen transfer and power requirements in activated
sludge wastewater treatment plant. Research Journal of Chemistry and Environment, ISSN 0972-0626, 2011, vol.
15, no. 2, str. 1-3, graf. prikazi. [COBISS.SI-ID 15168534],
DOBERŠEK, Danijela, GORIČANEC, Darko, KROPE, Jurij. Use of drag-reducing additives in district heating systems. V:
The fifth International Conference on Thermal Engineering: Theory and Applications [also] ICTEA, May 10-14, 2010,
Marrakesh, Morocco. Proceeding. [S. l.]: ICTEA, cop. 2010, str. 231-234. [COBISS.SI-ID 14194454]
65
Termodinamika zmesi
Predmet:
Course title:
UČNI NAČRT PREDMETA / COURSE SYLLABUS
Termodinamika zmesi
Solution Thermodynamics
Študijski program in stopnja
Study programme and level
Študijska smer
Study field
Letnik
Academic year
Semester
Semester
Kemijska tehnika / 2. stopnja
Chemical Engineering / 2nd level
Kemijska tehnika
Chemical Engineering
2.
zimski
Autumn
Vrsta predmeta / Course type:
Izbirni / Elective
Univerzitetna koda predmeta / University course code:
Predavanja
Lectures
15
Seminar
Seminar
Nosilec predmeta / Lecturer:
Jeziki /
Languages:
Sem. vaje
Tutorial
Lab. vaje
Labor work
15
Teren. vaje
Field work
Samost. delo
Individ. work
150
ECTS
6
Mojca Škerget
Predavanja / Lecture: slovenski / Slovene
Vaje / Tutorial: slovenski / Slovene
Pogoji za vključitev v delo oz. za opravljanje
študijskih obveznosti:
Prerequisites:
Osnovno znanje termodinamike
Basic knowledge of thermodynamics
Vsebina:
Predavanja
 Termodinamika faznih ravnotežij: osnovne
enačbe in parcialni odvodi, lastnosti čistih snovi
in realnih zmesi in metode določanja, enačbe
stanja, fugativnost in fugativnostni koeficient,
aktivnost in aktivnostni koeficient.
 Termodinamski opis zmesi:
Parcialne molarne količine, presežne količine,
fugativnost, aktivnost in aktivnostni koeficient.
 Večfazni sistemi: ravnotežje in stabilnost, fazni
prehodi.
 Fazni diagrami ter termodinamski in empirični
modeli za opis ravnotežij v sistemih plintekoče, tekoče-tekoče, trdno-tekoče in
sistemih pri visokih tlakih.
Content (Syllabus outline):
Lectures
 Classical thermodynamics of phase equilibria:
basic equations and partial derivatives, properties
of pure substances and real mixtures and methods
for determination, equations of state, fugacity and
activity.
 The thermodynamic description of mixtures:
partial molar properties, excess properties,
fugacity, activity and activity coefficient.
 Multiphase systems: Equilibrium and stability,
phase transitions.
 Phase diagrams, thermodynamic and empirical
models for description of equilibria in systems
Gas-liquid, Liquid-liquid, Solid-liquid, and systems
at high pressure.
Računalniške vaje:
Izračun faznih ravnotežij z uporabo programskih
orodij (npr. Aspen Plus,…):
Computational work:
Calculation of phase equilibria using software (e.g
Aspen Plus,…):
66
-
Izračun ravnotežij v sistemih plin-tekoče,
Topnost plinov v tekočinah,
Topnost trdnih snovi v tekočinah,
Ravnotežja v sistemih pri visokih tlakih.
-
Calculation of gas-liquid equilibria,
Solubility of gasses in liquids,
Solubility of solids in liquids,
High pressure equilibria,
Temeljni literatura in viri / Textbooks:
 J. V. Sengers, R. F. Kayser, C. J. Peters and H. J. White, Jr., Equations of State for Fluids and Fluid
Mixtures, Elsevier Science B. V., 2000.
 J. M.Prausnitz, R. N.Lichtenthaler, E. G. de Azevedo, Molecular thermodynamics of Fluid-Phase
Equilibria, 3rd ed., Prentice Hall, New Jersey, 1998.
Dodatna priporočena literatura:
 Stanley T. Sander, Chemical, Biochemical, and Engineering Thermodynymics, John Wiley&Sons, 2006.
 High-Pressure Fluid Phase Equilibria, Volume 2: Phenomenology and Computation (Supercritical Fluid
Science and Technology), Eds.: U. K Deiters, Thomas Kraska, Elsevier; 1 edition, 2012.
Cilji in kompetence:
Uporaba termodinamike v mešanicah, s
poudarkom na neidealnih mešanicah. Splošne
metode, enačbe stanja in drugi termodinamski
modeli, potrebni za kvantitativno obravnavanje
mešanic in večkomponentnih zmesi.
Objectives and competences:
Application of thermodynamics to mixtures
(solutions), with emphasis on non-ideal mixtures.
Generalized methods, equations of state and other
thermodynamic models, needed for quantitative
treatment of mixtures and multicomponent
mixtures.
Predvideni študijski rezultati:
Znanje in razumevanje:
Po zaključku tega predmeta bo študent sposoben
 razumeti zakone termodinamike na višjem
nivoju, predvsem za mešanice, večsnovne
sisteme in večkomponentne raztopine;
 uporabiti enačbe stanja za večsnovne sisteme;
 obvladati termodinamske izračune za takšne
sisteme.
Intended learning outcomes:
Knowledge and Understanding:
On completion of this course the student will be
able to
 understand laws of thermodynamics on a higher
level, above all for mixtures, multicomponent
mixtures and solutions;
 use equations of state for multicomponent
systems;
 govern in a great extend thermodynamic
calculations for such systems
Transferable/Key Skills and other attributes:
Communication skills, preferable the capability of
collecting needed information's for thermodynamic
calculations in mixtures. Solution of more
sophisticated thermodynamic problems.
Prenesljive/ključne spretnosti in drugi atributi:
Spretnost komuniciranja, predvsem sposobnost
zbiranja potrebnih informacij za termodinamske
izračune v zmeseh. Reševanje bolj zapletenih
termodinamskih problemov.
Metode poučevanja in učenja:
 predavanja
 računalniške vaje
Načini ocenjevanja:
Izpit je opravljen, če so pozitivno
opravljene vse naslednje obveznosti:
Ocenjevanje predmeta
 Projektno delo (računalniške vaje)
 Ustni izpit
Learning and teaching methods:
 Lectures
 Computer work
Delež (v %) /
Weight (in %)
Assessment:
Student has to pass successfully the
following obligations:
50
50
67
Assessment of the subject
 Project (computational work)
 Defense of the project and oral exam
Reference nosilca / Lecturer’s references:
ŠKERGET, Mojca, ČUČEK, Denis, KNEZ, Željko. Phase equilibria of the propylene glycol/CO2 and propylene
glycol/ethanol/CO2 systems. The Journal of supercritical fluids, ISSN 0896-8446. [Print ed.], Nov. 2014, vol. 95, str.
129-136, [COBISS.SI-ID 18135574].
PERKO, Tina, KNEZ, Željko, ŠKERGET, Mojca. Phase equilibria of glycerol tristearate and glycerol trioleate in carbon
dioxide and sulfur hexafluoride. Journal of chemical and engineering data, ISSN 0021-9568, 2012, vol. 57, no. 12,
str. 3604-3610, [COBISS.SI-ID 16419350].
ŠKERGET, Mojca, MANDŽUKA, Zoran, MARKOČIČ, Elena, KNEZ, Željko, JEŠE, Robi, ZNOJ, Bogdan, VENTURINI, Peter.
Solubility and diffusivity of CO2 in carboxylated polyesters. The Journal of supercritical fluids, ISSN 0896-8446.
[Print ed.], Jan. 2010, vol. 51, iss. 3, str. 306-311 [COBISS.SI-ID 13799446].
ŠKERGET, Mojca. Phase equilibrium in supercritical fluids : invited lecture presented at the International scientific
colloquium Center of applied spectroscopy, 29 - 30 September, 2011, UM FKKT, Maribor. 2011. [COBISS.SI-ID
15456534].
KNEZ, Željko, ŠKERGET, Mojca, KNEZ HRNČIČ, Maša. Principles of supercritical fluid extraction and applications in
the food, beverage and nutraceutical industries. V: RIZVI, Syed S. H. (ur.). Separation, extraction and concentration
processes in the food, beverage and nutraceutical industries. Oxford [etc.]: Woodhead Publishing Limited, 2010,
str. [3]-38. [COBISS.SI-ID 14789910].
PERKO, Tina, GUMZEJ, Jerneja, KNEZ, Željko, ŠKERGET, Mojca. Phase equilibria of flax seed oil - dense gases. V: 2nd
Conference on Applied Biocatalysis and 7th Meeting of Students and University Professors from Maribor and
Zagreb, November 7th and 8th 2011, Maribor, Slovenia. LEITGEB, Maja (ur.), PRIMOŽIČ, Mateja (ur.). 2nd
Conference on "Applied Biocatalysis" and 7th Meeting of Students and University Professors from Maribor and
Zagreb, November 7th and 8th 2011, Maribor, Slovenia. Maribor: Faculty of Chemistry and Chemical Engineering;
Zagreb: Faculty of Chemical Engineering and Technology, 2011, 4 str. [COBISS.SI-ID 15534358].
68
Upravljanje z okoljem
Predmet:
Course title:
UČNI NAČRT PREDMETA / COURSE SYLLABUS
Upravljanje z okoljem
Environmental Management
Študijski program in stopnja
Study programme and level
Kemijska tehnika / 2. stopnja
Chemical Engineering / 2nd level
Študijska smer
Study field
Kemijska tehnika
Chemical Engineering
Vrsta predmeta / Course type:
Letnik
Academic year
2.
Semester
Semester
zimski
Autumn
Izbirni / Elective
Univerzitetna koda predmeta / University course code:
Predavanja
Lectures
15
Seminar
Seminar
Nosilec predmeta / Lecturer:
Jeziki /
Languages:
Sem. vaje
Tutorial
15
Lab. vaje
Labor work
Teren. vaje
Field work
Samost. delo
Individ. work
150
ECTS
6
Damjan Krajnc
Predavanja / Lecture: slovenski / Slovene
Vaje / Tutorial: slovenski / Slovene
Pogoji za vključitev v delo oz. za opravljanje
študijskih obveznosti:
Ni pogojev.
Prerequisites:
Vsebina:
Predavanja:
Okoljski vplivi tehnoloških sistemov
Evropska zakonodaja in mednarodni standardi
Koncept in razvoj upravljanja z okoljem
Metode okoljskega in ekološkega pregleda
Teorija in praksa upravljanja z okoljem
Sistemi ravnanja z okoljem
Družbena odgovornost
Merjenje trajnostnega razvoja
Vseživljenjsko vrednotenje stroškov, okoljska
presoja
Večkriterijsko odločanje
Content (Syllabus outline):
Lectures:
Environmental impacts of technological systems
Environmental law, regulations and organizations
Concept and Development of Environmental
Management
Methods of Environmental and Ecological Auditing
Theory and Practice of environmental management
Environmental Management Systems
Corporate Social Responsibility
Measuring Sustainable Development
Life cycle costing, environmental impact assessment
Multi-criteria decision making
Seminar work:
Will be based on chosen topic: environmental laws and
regulations, implementation of environmental
management systems in chosen companies from
different industrial sectors, review of sustainability
reports of companies, examples of multi-criteria
decision making, environmental impact of production
processes, role of selected fields of technological
Seminarske vaje:
Osnovane na izbrani temi: okoljska zakonodaja in
predpisi, vzpostavitev sistemov upravljanja z
okoljem v izbranih podjetjih iz različnih sektorjev,
pregled poročil o trajnostnem razvoju podjetij,
primeri večkriterijskega odločanja pri upravljanju
z okoljem, okoljskih vplivi proizvodnih procesov,
None.
69
vloga in vpliv izbranih področij tehnološkega
razvoja na globalni trajnostni razvoj.
development in global sustainable development.
Temeljni literatura in viri / Textbooks:
 Krajnc D. Upravljanje z okoljem (zbrano gradivo), 2009, Univerza v Mariboru, Fakulteta za kemijo in
kemijsko tehnologijo, http://www.fkkt.um.si/egradiva/fajli/upravljanje_z_okoljem.pdf.
Dodatna priporočena literatura:
 Weiß P., Bentlage J., Environmental Management Systems and Certification, The Baltic University
Press, 2006.
 Mulder K. Sustainable Development for Engineers – A Handbook and Resource Guide. Greenleaf
Publishing Ltd, Sheffield UK, 2006.
Cilji in kompetence:
Razumevanje okoljskih vidikov in predpisov,
razvoja okoljskih strategij, poročanja o okoljskem in
trajnostnem delovanju, sistemov upravljanja z
okoljem, okoljskega računovodstva in pregledov,
večkriterijskega odločanja pri upravljanju z okoljem
Objectives and competences:
Understanding of environmental issues and
regulations, development of environmental
strategies, environmental and sustainability
performance reporting, environmental management
systems, environmental accounting and auditing,
multi-criteria decision making.
Predvideni študijski rezultati:
Intended learning outcomes:
nowledge and Understanding:
Znanje in razumevanje:
Po opravljenem predmetu bo študent sposoben Completing the course the student will be able to
prepoznati in razumeti pomembnost upravljanja z recognize and understand the importance of
okoljem za stanje podjetja glede okoljskih izzivov in environmental management for the situation of the
konkurenčnosti. Študent bo sposoben uporabljati company regarding environmental challenges and
metode okoljskih pregledov v podjetju in bo competitiveness. The student should be able to use
seznanjen s teorijo in postopki vpeljevanja sistemov methods of environmental and ecological auditing
upravljanja z okoljem v podjetju. Sposoben bo and be acquired with the theory and implementation
razviti okoljske strategije, uporabljati okoljske in procedure for environmental management systems
trajnostne kazalce, izvajati okoljsko merjenje in in companies. The student will be able to use
preglede ter vključevati večkriterijsko odločanje v environmental and sustainability performance
sistem upravljanja z okoljem. Pridobil bo znanje o indicators, environmental accounting and auditing
konceptih, teorijah, metodah in orodjih pri and implement multi-criteria decision making in the
environmental management. The student will
industrijskem upravljanju z okoljem.
acquire the knowledge of the concepts, theories,
methods and tools of industrial environmental
Prenesljive/ključne spretnosti in drugi atributi:
management.
Po opravljenem predmetu bo študent pridobil
naslednje spretnosti:
Transferable/Key Skills and other attributes:
 predlagati pristope k uvajanju upravljanja z
On the completion of the course the student will
okoljem v podjetju,
acquire the following skills:
 uporabljati metode okoljskega in ekološkega
 propose approaches for environmental
pregleda,
management implementation in company,
 načrtovati in voditi projekte, uporabljati metode
 use methods of environmental and ecological
večkriterijskega odločanja,
auditing,
 uporabljati informacijske tehnologije.
 plan and manage projects, use methods of multicriteria decision making,
 use information technologies.
70
Metode poučevanja in učenja:
Predavanja, vaje, samostojni študij problema,
izdelava posamične ali skupinske seminarske
naloge.
Načini ocenjevanja:
Izpit je opravljen, če so pozitivno opravljene
vse naslednje obveznosti:
 pisni izpit
 seminarska naloga
 predstavitev seminarske naloge
Learning and teaching methods:
Lectures, exercises, independent problem study,
carrying out the individual or team seminar work.
Delež (v %) /
Weight (in %)
50
40
10
Assessment:
Student has to pass successfully the
following obligations:
 written examination
 seminar work
 seminar work presentation
Reference nosilca / Lecturer’s references:
TOKOS, Hella, NOVAK-PINTARIČ, Zorka, KRAJNC, Damjan. An integrated sustainability performance assessment and
benchmarking of breweries. Clean technologies and environmental policy, 2012, vol. 14, no. 2, str. 173-193.
CZEKAJ, Marta, KRAJNC, Damjan. Sustainability assessment regarding the regional development of Sucha Beskidzka
County, Poland. Polish journal of environmental studies, ISSN 1230-1485, 2011, vol. 20, no. 4A, str. 50-56.
KOLETNIK, Damijan, LUKMAN, Rebeka, KRAJNC, Damjan. Environmental management of waste based on road
construction materials. Aplinkos tyrimai, inžinerija ir vadyba, ISSN 1392-1649, 2012, vol. 59, no. 1, str. 42-46.
71
Eko-dizajn in ocena življenjskega cikla
Predmet:
Course title:
UČNI NAČRT PREDMETA / COURSE SYLLABUS
Eko-dizajn in ocena življenjskega cikla
Eco-design and life cycle assessment
Študijski program in stopnja
Study programme and level
Kemijska tehnika / 2. stopnja
Chemical Engineering / 2nd level
Študijska smer
Study field
Kemijska tehnika
Chemical Engineering
Vrsta predmeta / Course type:
Letnik
Academic year
2.
Semester
Semester
zimski
Autumn
Izbirni / Elective
Univerzitetna koda predmeta / University course code:
Predavanja
Lectures
15
Seminar
Seminar
Nosilec predmeta / Lecturer:
Jeziki /
Languages:
Sem. vaje
Tutorial
15
Lab. vaje
Labor work
Teren. vaje
Field work
Samost. delo
Individ. work
150
ECTS
6
Damjan Krajnc
Predavanja / Lecture: slovenski / Slovene
Vaje / Tutorial: slovenski / Slovene
Pogoji za vključitev v delo oz. za opravljanje
študijskih obveznosti:
Ni pogojev
Prerequisites:
Vsebina:
 Uvod v industrijsko ekološko načrtovanje:
definicija in vloga v kemijski in procesnih
industrijah,
 Snovni tokovi in eko-načrtovanje (vplivi na
okolje in dileme, razpoložljivost in izčrpanost
surovinskih virov),
 Strategije in koncepti eko-načrtovanja razvoj
novega koncepta, raba materialov in vsebnost
kemikalij, zmanjšanje snovnih tokov in porabe
energije, načrtovanje za proizvodnjo,
distribucijo, uporabo, odstranitev,
podaljševanje življenjske dobe),
 Določitev ciljev in področja (ozadje analize,
zahteve glede modeliranja, načrtovanje študije
LCA),
 Inventarizacija (priprava diagrama poteka,
zbiranje podatkov, postopek izračuna,
alokacija),
 Analiza življenjskega cikla (okoljski vplivi,
različne faze LCIA, metode karakterizacije)
Content (Syllabus outline):
- Introduction to Industrial Eco-Design: definition
and role in chemical and process industries,
- Resources flow and eco-design (environmental
impact and dilemma of resource flows, resource
availability and depletion),
- Strategies and concepts of eco-design new
concept development, materials application and
chemical content, reducing material flows,
reduction of energy consumption, design for
production, distribution, use, end-of-life,
product lifetime extension),
- Goal and scope definition (context of the study,
modelling requirements, planning of an LCA
study),
- Inventory analysis (construction of a flowchart,
data collection, calculation procedure,
allocation),
- Life cycle impact assessment (what is an
environmental impact, different phases of life
cycle impact assessment, characterisation
None
72
 Razlaga in prikaz rezultatov (kvantitativni
rezultati, testiranje robustnosti rezultatov),
 Kritični pregled LCA,
 Upravljanje podatkov LCA (programski paketi,
baze podatkov, dokumentiranje LCA),
methods),
- Interpretation and presentation of results
(quantitative results, testing the robustness of
the results),
- Critical review of LCA,
- LCA data management (software packages,
databases, documentation of LCA)
- Green marketing, procurement and ecolabelling;
- Product-oriented environmental policies.
 Zeleno oglaševanje, nabavljanje in okoljsko
označevanje,
 Okoljska politika do proizvodov.
Seminarske vaje:
študent bo z metodologijo, orodji in programsko
opremo obdelal določen problem iz področja ekodizajna in metode ocenjevanja življenjskega cikla.
Seminar work:
Student will independently solve problem in the
field of eco-design and life cycle assessment using
methodology, tools and software.
Temeljni literatura in viri / Textbooks:
 Krajnc D. 2014. Eko-dizajn - Okoljsko načrtovanje, razvoj in analiziranje proizvodov in procesov.
Univerza v Mariboru, Fakulteta za kemijo in kemijsko tehnologijo.
Dodatna priporočena literatura:
 Zbiciński I., Stavenuiter J., Kozlowska B., van de Coevering H.P.M. 2006. Product Design and Life Cycle
Assessment. The Baltic University Press.
 Bauman H., Tillman A.M. 2004. The Hitch Hiker's Guide to LCA. Studentlitteratur AB.
 European Commission - Joint Research Centre - Institute for Environment and Sustainability:
International Reference Life Cycle Data System (ILCD) Handbook - General guide for Life Cycle
Assessment - Detailed guidance. First edition March 2010. EUR 24708 EN. Luxembourg. Publications
Office of the European Union; 2010.
73
Cilji in kompetence:
Objectives and competences:
Razumevanje metodologije okoljskega načrtovanja,
poznavanje metod ocenjevanja vplivov na okolje v
celotnem življenjskem ciklu proizvoda, metod
načrtovanja posameznih faz življenjskega cikla,
poznavanje in uporaba ustrezne programske
opreme za okoljsko načrtovanje proizvodov.
Understanding the eco (re)design methodologies
and tools, understanding environmental impact
assessment methods, be able to design life cycle
phases of products, and use the eco design and LCA
software.
Predvideni študijski rezultati:
Znanje in razumevanje:
Študent mora biti sposoben izvesti analizo
življenjskega cikla proizvoda, z obstoječimi orodji in
programsko opremo ovrednotiti vplive na okolje v
vseh fazah življenjskega cikla, obvladati tehnike
izboljšanja obstoječih in načrtovanja novih
proizvodov ter procesov, ki bodo imeli ekonomsko
in okoljsko sprejemljive vplive na okolje in stroške.
Intended learning outcomes:
Knowledge and Understanding:
Student should be able to perform the LCA of a
product, with the help of existing tools and software
to carry out environmental impact assessment of all
product life cycle phases, be able to develop new
concepts of products (existing and/or new ones) and
processes with environmentally and economically
acceptable impacts on the environment and costs
Prenesljive/ključne spretnosti in drugi atributi:
Celostni pristop k načrtovanju proizvodov in/ali
storitev.
Poznavanje metodologij okoljskega načrtovanja
proizvodov in storitev.
Uporaba osnovnih metod okoljskega izboljšanja
obstoječih in načrtovanja novih procesov.
Transferable/Key Skills and other attributes:
Integral approach to the eco (re)design of products
and services.
Knowledge of the methodologies to be used in eco
(re)design.
Application of the basic methods and environmental
improvements of the existing and new processes.
Metode poučevanja in učenja:
Predavanja, vaje, samostojni študij problema,
izdelava posamične ali skupinske seminarske
naloge.
Learning and teaching methods:
Lectures, exercises, independent problem study,
carrying out the individual or team seminar work.
Načini ocenjevanja:
Izpit je opravljen, če so pozitivno
opravljene vse naslednje obveznosti:
- pisni
- seminarska naloga
- predstavitev seminarske naloge
Delež (v %) /
Weight (in %)
50
40
10
Assessment:
Student has to pass successfully the
following obligations:
- written examination
- seminar work
- seminar work presentation
Reference nosilca / Lecturer’s references:
KRAJNC, Damjan. Okoljski vplivi različnih nagrobnih sveč in metoda LCA. Embalaža, okolje, logistika, ISSN 18554849, nov. 2010, št. 54.
KRAJNC, Damjan. Vzpostavljanje ekoindustrijskih sistemov z načeli industrijske simbioze = The establishment of
eco-industrial systems including the principles of industrial symbiosis. V: VOLFAND, Jože (ur.), ČERNUTA, Uroš.
Odpadki v Sloveniji = Waste in Slovenia, (Zbirka Zelena Slovenija). Celje: Fit media, 2010.
RADONJIČ, Gregor, PISNIK, Aleksandra, KRAJNC, Damjan. Product ecodesign in companies with ISO 14001 certified
environmental management system. Environmental engineering and management journal, ISSN 1582-9596. Jan.
2015, vol. 14, no. 1, str. 176-181.
TOKOS, Hella, NOVAK-PINTARIČ, Zorka, KRAJNC, Damjan. An integrated sustainability performance assessment and
benchmarking of breweries. Clean technologies and environmental policy, 2012, vol. 14, no. 2, str. 173-193.
ZHOU, Li, TOKOS, Hella, KRAJNC, Damjan, YANG, Yongrong. Sustainability performance evaluation in industry by
composite sustainability index. Clean technologies and environmental policy, Oct. 2012, vol. 14, iss. 5, str. 789-803.
74
Surovine in proizvodnja premazov
Predmet:
Course title:
UČNI NAČRT PREDMETA / COURSE SYLLABUS
Surovine in proizvodnja premazov
Raw Materials and Manufacture of Coatings
Študijski program in stopnja
Study programme and level
Kemijska tehnika / 2. stopnja
Chemical Engineering / 2nd level
Študijska smer
Study field
Kemijska tehnika
Chemical Engineering
Vrsta predmeta / Course type:
Letnik
Academic year
2.
Semester
Semester
zimski
Autumn
Izbirni / Elective
Univerzitetna koda predmeta / University course code:
Predavanja
Lectures
15
Seminar
Seminar
Nosilec predmeta / Lecturer:
Jeziki /
Languages:
Sem. vaje
Tutorial
15
Lab. vaje
Labor work
Teren. vaje
Field work
Samost. delo
Individ. work
150
ECTS
6
Mojca Škerget
Predavanja / Lecture: slovenski / Slovene
Vaje / Tutorial: slovenski / Slovene
Pogoji za vključitev v delo oz. za opravljanje
študijskih obveznosti:
Osnovno znanje organske kemije z dodiplomskega
študija.
Prerequisites:
Vsebina:
 kaj so premazi: definicije, sestava.
 veziva: naravna, modificirana naravna,
sintetična.
 topila: klasifikacija in definicije, karakterizacija
topil, lastnosti, topila v premaznih materialih.
 pigmenti in polnila: definicije in klasifikacija,
fizikalne, beli pigmenti, črni pigmenti,
anorganski barvni pigmenti, organski barvni
pigmenti, sijajni pigmenti, funkcionalni
pigmenti, polnila, barve.
 aditivi: definicije in klasifikacija, površinsko
aktivni aditivi, reološki aditivi, stabilizatorji
svetlobe, biocidi, močljivci in dispergirna
sredstva, katalizatorji in sušilna sredstva.
 zakonodaja.
 barve in premazni sistemi, formulacija, tvorba
filma (sušenje, zamreženje):
 sestava barv, osnovni parametri
formuliranja, lastnosti filma.
Content (Syllabus outline):
 What are coatings: definitions, composition.
 Film formers: Natural, Modified natural,
Synthetic.
 Solvents: Classification and definitions,
Characterisation of solvents, Properties,
Solvents in coating materials.
 Pigments and fillers: Definitions and
classification, pigment physic, White pigments,
Black pigments, Inorganic coloured pigments,
Organic coloured pigments, Lustre pigments,
Functional pigments, Fillers, Dyes.
 Additives: Definitions and classification,
Interface-active additives, Rheological additives,
Light stabilizers, Biocides, Wetting and
dispersing agents, Catalysts and driers, Flatting
agents.
 Legislative Framework.
 Paint systems, formulation, film-forming (drying
and curing, crosslinking):
Basic knowledge of organic chemistry from
undergraduate study.
75


barve na osnovi topil, barve na vodni
osnovi, radikalsko zamrežljivi premazni
materiali, praškasti premazi, anorganski
premazni materiali.
 tvorba filma, sušenje in zamreženje.
proizvodnja barv in premazov:
 procesne stopnje v proizvodnji premazov,
naprave, formuliranje obdelovalne osnove,
mešanje in raztapljanje, dispergiranje,
drobljenje in gnetenje, filtracija,
dispergiranje efektnih pigmentov, šaržni
testi
 Specifične lastosti proizvodnje vodnih
lakov.
 Proizvodnja praškastih premazov.
Vaje:
primeri premaznih sistemov, študij njihovih
fizikalno kemijskih lastnosti ter vpliva na lastnosti
premaza in možne napake, formulacije, sušenja in
zamreženja premazov.


Composition of paints, Basic formulating
parameters film properties.
 Solvent-based paints, Waterborne paints,
Radically-curing coating materials, Coating
powders, Inorganic coating materials.
 Film-forming, drying, curing (crosslinking).
Manufacture of paints and coatings:
 Process stages in the manufacture of
coatings, Configuration of equipment,
Formulating the mill base, Mixing and
dissolving, Dispersion, Grinding and
kneading, Filtration, Dispersing effect
pigments, Batch tests.
 Special features of the production of
waterborne enamels.
 Manufacture of coating powders.
Tutorial:
Case study of coating types, their physical and
chemical properties and influence on coating
properties and common failure modes, formulation
and film-forming (drying and curing, crosslinking).
Temeljni literatura in viri / Textbooks:
 Goldschmidt, H. J. Streitberger: BASF-Handbuch Lackiertechnik, Vincentz, Hannover, 2002.
 B. Müller, U. Poth: Coatings formulation, Hannover: Vincentz, 2006.
Dodatna priporočena literatura:
 K. Hunger (Ed.): Industrial Dyes, Chemistry, Properties, Applcations, Wiley-VCH, Weinheim, 2003.
 H. Kittel, J. Spille (Hrsg.): Lehrbuch der Lacke und Beschichtungen, Bd. 5.; Hirzel, Stuttgart, 2003.
 T. Brock, M. Groteklaes, P. Mischke: European Coatings Handbook, Curt R. Vincentz Verlag, Hannover
2000.
Cilji in kompetence:
Cilj tega predmeta je osvojiti znanja o vrstah
premaznih sistemov in njihovih surovinah ter o
formuliranju, lastnostih ter procesnih stopnjah.
Objectives and competences:
The objective of this course is to achieve knowledge
of the coating systems, raw materials for coatings,
formulation, properties, and process stages.
Predvideni študijski rezultati:
Znanje in razumevanje:
 Poznavanje surovin za premaze in njihove
lastnosti ter vpliv na lostnosti premaza;
 Poznavanje zakonodaje;
 Osnovne sestave in formuliranja premaznih
sistemov, tipov premaznih materialov in njihovih
lastnosti, tehnologij sušenja in zamreženja,
mešanje in dispergiranje v proizvodnji barv.
Intended learning outcomes:
 Knowledge and Understanding:
 Knowledge of raw materials for coatings,
properties of specific compounds and the
influence on the coating properties;
 Legislation;
 Basics of composition and formulations of paints,
types of coating materials and their properties,
technology of drying and curing, mixing and
grinding (dispersing).
Transferable/Key Skills and other attributes:
 Achieving basic knowledge for the work in the
industry of paints and coatings
Prenesljive/ključne spretnosti in drugi atributi:
 osnovna predznanja za delo v industriji barv in
lakov
76
Metode poučevanja in učenja:
Predavanja, seminarske vaje, strokovna ekskurzija v
industrijo.
Seminarska naloga: študent izdela krajšo študijo oz.
projekt, ki se navezuje na tematiko predmeta.
Načini ocenjevanja:
Izpit je opravljen, če so pozitivno
opravljene vse naslednje obveznosti:
 pisni izpit
 seminarska naloga
Learning and teaching methods:
Lectures, tutorial, visit to the industry.
Individual project work: conducting a short study
(project) regarding the thematic of the subject.
Delež (v %) /
Weight (in %)
60
40
Assessment:
Student has to pass successfully the
following obligations:
 written examination
 Seminar work report
Reference nosilca / Lecturer’s references:
ŠKERGET, Mojca, ČUČEK, Denis, KNEZ, Željko. Phase equilibria of the propylene glycol/CO2 and propylene
glycol/ethanol/CO2 systems. The Journal of supercritical fluids, ISSN 0896-8446. [Print ed.], Nov. 2014, vol. 95, str.
129-136, doi: 10.1016/j.supflu.2014.08.019. [COBISS.SI-ID 18135574]
ČUČEK, Denis, PERKO, Tina, ILIĆ, Ljiljana, ZNOJ, Bogdan, VENTURINI, Peter, KNEZ, Željko, ŠKERGET, Mojca. Phase
equlibiria[!] and diffusivity of dense gases in various polyethylenes. The Journal of supercritical fluids, ISSN 08968446. [Print ed.], June 2013, vol. 78, str. 54-62, doi: 10.1016/j.supflu.2013.03.020. [COBISS.SI-ID 16830998],
ŠKERGET, Mojca, MANDŽUKA, Zoran, MARKOČIČ, Elena, KNEZ, Željko, JEŠE, Robi, ZNOJ, Bogdan, VENTURINI, Peter.
Solubility and diffusivity of CO2 in carboxylated polyesters. The Journal of supercritical fluids, ISSN 0896-8446.
[Print ed.], Jan. 2010, vol. 51, iss. 3, str. 306-311, doi: 10.1016/j.supflu.2009.10.013. [COBISS.SI-ID 13799446]
KNEZ, Željko, ŠKERGET, Mojca, KNEZ HRNČIČ, Maša, ČUČEK, Denis. Particle formation using sub- and supercritical
fluids. V: ANIKEEV, Vladimir (ur.), FAN, Maohong (ur.). Supercritical fluid technology for energy and environmental
applications. Amsterdam: Elsevier, 2014, str. 31-67, doi: 10.1016/B978-0-444-62696-7.00002-2. [COBISS.SI-ID
17592854]
ŠKERGET, Mojca. Formuliranje prašnih lakov z visokotlačnim postopkom : zaključno poročilo o rezultatih
raziskovalnega projekta. Maribor: Fakulteta za kemijo in kemijsko tehnologijo, 2011. loč. pag. [COBISS.SI-ID
14953238]
77
Aplikacija, lastnosti in testiranje premazov
Predmet:
Course title:
UČNI NAČRT PREDMETA / COURSE SYLLABUS
Aplikacija, lastnosti in testiranje premazov
Application, Properties and Testing of Coatings
Študijski program in stopnja
Study programme and level
Kemijska tehnika / 2. stopnja
Chemical Engineering / 2nd level
Študijska smer
Study field
Kemijska tehnika
Chemical Engineering
Vrsta predmeta / Course type:
Letnik
Academic year
2.
Semester
Semester
zimski
Autumn
Izbirni / Elective
Univerzitetna koda predmeta / University course code:
Predavanja
Lectures
15
Seminar
Seminar
Nosilec predmeta / Lecturer:
Jeziki /
Languages:
Sem. vaje
Tutorial
Lab. vaje
Labor work
7,5
Teren. vaje
Field work
7,5
Samost. delo
Individ. work
150
ECTS
6
Mojca Škerget
Predavanja / Lecture: slovenski / Slovene
Vaje / Tutorial: slovenski / Slovene
Pogoji za vključitev v delo oz. za opravljanje
študijskih obveznosti:
Osnovno znanje organske in analizne kemije z
dodiplomskega študija.
Prerequisites:
Vsebina:
 substrati in predobdelava: kovinski substrati,
substrati iz umetnih mas, substrati iz lesa,
mineralni substrati.
 aplikacija in sušenje: metode uporabe in
pogoji, ročni nanos, nanos s polivanjem, nanos
z valji, potopno in poplavno barvanje in
sorodne tehnike, razpršilno barvanje (metode z
in brez elektrostatičnega naboja), praškasti
premazi, razpršilne komore, sušilne naprave.
 primeri procesov barvanja (avtomobilska
industrija, umetne mase, lesna industrija in
ostali industrijski procesi).
 okolju prijazne barve in premazi (premazi s
povišano vsebnostjo trdne snovi, vodni
Content (Syllabus outline):
 Substrates and pretreatment: Metal substrates,
Plastic substrates, Wood substrates, Mineral
substrates.
 Application and drying: Methods of application
and criteria for use, Manual application by
brushing, rolling, trowelling, wiping, Curtain
coating, Roller coating, Dipping, flow coating
and related applications, Electrodeposition
coating, Spray application (methods without and
with electrostatic charging), Powder coating,
Spray booths, Drying installations.
 Examples of coatings processes (automotive, car
refinishing, plastic coating, other industrial
processes, wood coating).
Basic knowledge of organic and analytical chemistry
from undergraduate study.
78







premazi, suspenzije, praškasti premazi, z
radiacijo zamrežljive barve in laki, ostali
premazni sistemi).
reologija in reometrija: osnove reologije,
meritve pretočnih lastosti, viskoelastičnost.
značilnosti tekočih in trdnih produktov.
analitske vrednosti za trdne produkte.
testiranje tekočih barv in premazov: optične
lastnosti, emisija, tvorba filma, tečenje in
zamreženje, obstojnost.
specifični testi za praškaste premaze.
lastnosti premazov po aplikaciji: merjenje
debeline filma, optične lastnosti filma, barva in
kolorimetrija, Mehanske lastnosti filma,
svetlobna obstojnost in vodoodpornost.
obstojnost premazov in premaznih sistemov.








Vaje:
 uporaba standardnih analiznih metod za
testiranje premaznih sistemov in premazov:
testiranje mehanskih lastnosti, reoloških
lastnosti, kemijske obstojnosti, obstojnosti na
zunanje vplive.
 ekskurzija v industrijo.
Environment Compatible Paints and Coatings
(High Solids, Waterborne Paints, Slurry, Powder
Coatings, Radiation Curable Paints and Coatings,
Other Coating Systems).
Rheology and rheometry: Rheological principles,
Measuring flow behaviour, Viscoelasticity.
Characteristics of solvents and liquid products:
Analytical values for solids.
Testing of liquid paints and coatings: Optical
properties, Emissions, Film-forming, flow and
crosslinking, Ring circuit stability.
Specific tests for coating powders.
Features of coatings after application: Film
thickness measurement, Optical film properties,
colour and colorimetry, Mechanical film
properties, Light stability and weather
resistance.
Durability of coatings and coating systems.
Labor work:
 Application of standard analytical methods for
testing of coating systems and coatings: testing
of mechanical properties, rhheological
properties, chemical resistance, weathering
resistance.
 Visit to the industry.
Temeljni literatura in viri / Textbooks:
 P. A. Schweitzer, Paint and Coatings: Applications and Corrosion Resistance, Taylor & Francis Group
Boca Raton, 2006.
 D. G. Weldon, Failure Analysis of Paints and Coatings, John Wiley & Sons Inc., 2001.
Dodatna priporočena literatura:
 R. Dietrich, Paint Analysis, Vincentz Network, Hannover, 2009.
 T. Brock, M. Groteklaes, P. Mischke: European Coatings Handbook, Curt R. Vincentz Verlag, Hannover
2000. [ISBN: 3-87870-559-X].
 Goldschmidt, A; Streitberger: H.-J., BASF-Handbuch Lackiertechnik, Vincentz: Hannover, 2002.
Cilji in kompetence:
Osvojiti znanja o optimalnih tehnikah nanosa in
sušenja za različne premazne sisteme ter znanja o
lastnostih premaznih sistemov, možnih napakah in
analiznih metodah.
Objectives and competences:
Achieving knowledge about optimal application and
drying techniques of different coating systems and
properties of coating systems, possible failures and
analytical methods.
Predvideni študijski rezultati:
Znanje in razumevanje:
 Poznavanje različnih tehnik nanosa tekočih in
praškastih premazov.
 Sposobnost izbire najboljše tehnike nanosa za
dan primer kot tudi najboljše tehnike sušenja oz
zamreženja z vidika kvalitete, ekonomike in
ekologije.
 Poznavanje lastnosti premaznih sistemov.
Intended learning outcomes:
Knowledge and Understanding:
 Variety of applications of fluid and powderous
coating materials;
 Selecting best method for a given challenge as
well as the best drying resp. curing way
depending on quality, economical and ecological
view points;
 Of properties of coating systems;
79
 Poznavanje merilnih tehnik in analiznih metod za
testiranje premazov.
 Of analytical methods and measuring technics for
testing coatings.
Prenesljive/ključne spretnosti in drugi atributi:
osnovna predznanja za delo v industriji barv in
lakov oz. na področjih njihove uporabe.
Transferable/Key Skills and other attributes:
Achieving basic knowledge for the work in the
industry of paints and coatings and areas of their
application.
Metode poučevanja in učenja:
 predavanja
 strokovna ekskurzija v industrijo
 laboratorijske vaje
Learning and teaching methods:
 Lectures
 Visit to the industry
 Laboratory work
Načini ocenjevanja:
Izpit je opravljen, če so pozitivno
opravljene vse naslednje obveznosti:
 laboratorijske vaje
 pisni izpit
Delež (v %) /
Weight (in %)
30
70
Assessment:
Student has to pass successfully the
following obligations:
 Laboratory work
 Written examination
Reference nosilca / Lecturer’s references:
ŠKERGET, Mojca, ČUČEK, Denis, KNEZ, Željko. Phase equilibria of the propylene glycol/CO2 and propylene
glycol/ethanol/CO2 systems. The Journal of supercritical fluids, ISSN 0896-8446. [Print ed.], Nov. 2014, vol. 95, str.
129-136, doi: 10.1016/j.supflu.2014.08.019. [COBISS.SI-ID 18135574]
ČUČEK, Denis, PERKO, Tina, ILIĆ, Ljiljana, ZNOJ, Bogdan, VENTURINI, Peter, KNEZ, Željko, ŠKERGET, Mojca. Phase
equlibiria[!] and diffusivity of dense gases in various polyethylenes. The Journal of supercritical fluids, ISSN 08968446. [Print ed.], June 2013, vol. 78, str. 54-62, doi: 10.1016/j.supflu.2013.03.020. [COBISS.SI-ID 16830998],
ŠKERGET, Mojca, MANDŽUKA, Zoran, MARKOČIČ, Elena, KNEZ, Željko, JEŠE, Robi, ZNOJ, Bogdan, VENTURINI, Peter.
Solubility and diffusivity of CO2 in carboxylated polyesters. The Journal of supercritical fluids, ISSN 0896-8446.
[Print ed.], Jan. 2010, vol. 51, iss. 3, str. 306-311, doi: 10.1016/j.supflu.2009.10.013. [COBISS.SI-ID 13799446]
KNEZ, Željko, ŠKERGET, Mojca, KNEZ HRNČIČ, Maša, ČUČEK, Denis. Particle formation using sub- and supercritical
fluids. V: ANIKEEV, Vladimir (ur.), FAN, Maohong (ur.). Supercritical fluid technology for energy and environmental
applications. Amsterdam: Elsevier, 2014, str. 31-67, doi: 10.1016/B978-0-444-62696-7.00002-2. [COBISS.SI-ID
17592854]
ŠKERGET, Mojca. Formuliranje prašnih lakov z visokotlačnim postopkom : zaključno poročilo o rezultatih
raziskovalnega projekta. Maribor: Fakulteta za kemijo in kemijsko tehnologijo, 2011. loč. pag. [COBISS.SI-ID
14953238]
80
Teorija membranskih transportov
Predmet:
Course title:
UČNI NAČRT PREDMETA / COURSE SYLLABUS
Teorija membranskih transportov
Theory of Membrane Transport
Študijski program in stopnja
Study programme and level
Študijska smer
Study field
Letnik
Academic year
Semester
Semester
2.
Zimski
Autumn
Kemijska tehnika / 2. stopnja
Chemical Engineering / 2nd level
Vrsta predmeta / Course type:
Izbirni / Optional
Univerzitetna koda predmeta / University course code:
Predavanja
Lectures
Seminar
Seminar
Sem. vaje
Tutorial
15
Nosilec predmeta / Lecturer:
Jeziki /
Languages:
Lab. vaje
Laboratory
work
15
Teren. vaje
Field work
Samost. delo
Individ. work
ECTS
150
6
Irena Petrinić
Predavanja / Lectures: slovenščina / Slovene
Vaje / Tutorial: slovenščina / Slovene
Pogoji za vključitev v delo oz. za opravljanje
študijskih obveznosti:
Splošno znanje fizike, kemije in matematike.
Prerequisits:
Vsebina:
 Membranski proces je proces separacije, ki
zajema širok spekter problemov, od delcev do
molekul. Na voljo so različne membrane za
izvedbo procesov. Četudi so membrane lahko iz
različnih materialov(organskega ali
anorganskega izvora) in različne strukture (
porozne ali nepozorne), je osnovni princip
ločevanja enak. Ta predmet vključuje:
 Zgodovinski pregled razvoja membran
 Membrane in klasifikacija membranskih
procesov
 Pretok skozi porozne/neporozne membrane
 Mehanizmi mašenja
 Upad pretoka
 Membranski procesi v okoljski tehnologiji:
proizvodnja pitne vode, recikliranje odpadne
vode, dodatno čiščenje vode
Content (Syllabus outline):
 A membrane process is a separation process
that covers a broad range of problems from
particles to molecules and a wide variety of
membranes are available to design a process.
Although the membranes may vary in material
(organic, inorganic) and structure (porous,
nonporous) the basic principle of membrane
separation is the same. This course covers:
 An overview of the historical development of
membranes
 Membranes and classification of membrane
processes
 Transport through porous/nonporous
membranes
 Fouling mechanisms
 Flux decline
 Membrane processes in environmental
General knowledge of chemistry, physics and
mathematics
81
Seminarske vaje:
Vaje se navezujejo na tematiko predmeta.
Študent samostojno reši nekaj praktičnih primerov
technology: production of drinking water,
recycling of wastewater, additional polishing
Tutorials will be based on chosen topic regarding
the theme of the subject. Students individually solve
several practical examples.
Temeljni literatura in viri / Readings:
 Mulder, Marcel, Basic Principles of Membrane Technology, Kluwer Academic Publishers, Dordrecht,
Netherlands, 2003.
 Baker, R.W., Membrane technology and applications, 2nd ed., John Wiley, 2012.
Dodatna priporočena literatura:
 Judd, S. Jefferson, B. Membranes for Industrial Wastewater Recovery and re-use. New York: Elsevier
Advanced Technology, 2003.
 Noble, Richard D., Stern, S. Alexander (Eds), Membrane Separations Technology - Principles and
Applications, Elsevier, 1995.
 Primarna literatura (npr. članki) s tematiko glede na študentovo področje raziskovanja /Primary
literature (e.g. papers) corresponding to the student’s research interest.
Cilji in kompetence:
Cilj predmeta je, da študentje pridobijo:
 Pregled osnov membranske filtracijske
tehnologije, membrane, in oblike membranskih
modulov, membranskih filtracijskih sistemov in
uporabo membranskih filtracij na področju
obdelave odpadne vode
 Pridobili bodo znanje membranske tehnologije
in membranskih procesov ter njihovih aplikacij
 Študenti bodo razvili sposobnost oblikovanja in
reševanja inženirskih problemov, ki vključuje
oblikovanje membran in membranskih modulov
 Zagotoviti razumevanje splošnih načel
separacijskih procesov, da študent vidi možnosti
na dejanskih primerih separacijskih procesov
Objectives and competences:
This course aims to give students:
 An overview of the fundamentals of membrane
filtration technology, membranes and
membrane modules configuration, membrane
filtration system configurations and membrane
applications in the field of wastewater
treatment
 They will get the knowledge of membrane
technology, membrane processes and
applications
 To develop the student's ability to formulate
and solve engineering problems involving
design of membranes and membrane modules
 To provide an understanding of the general
principles of separation processes to allow
students to make sensible options given a
separation task
Predvideni študijski rezultati:
Znanje in razumevanje:
 S pridobitvijo znanja teorije, mehanizma
delovanja in tehnološkega razvoja bo
študentom dalo orodje za uporabo te relativno
nove tehnologije tekom svojih raziskovanj in
tudi na njihovih prihodnjih delovnih mestih.
 Študent bo pridobil izkušnje in znanje na osnovi
individualnega raziskovalnega dela.
Intended learning outcomes:
Knowledge and understanding:
 By getting knowledge on the theory, mechanism
and technology development, this will give the
students new tools in using this relatively new
technology in their research and also in their
future jobs.
 The student shall gain experience and
knowledge with regard to individual, scientific
work.
Transferable/Key Skills and other attributes:
 Ability to determine the optimal membrane
process, and predict membrane fouling for
specific wastewater treatment
Prenesljive/ključne spretnosti in drugi atributi:
 Sposobnost izbrati optimalni membranski
proces in napovedati mehanizem mašenja
membran gleda na specifičnost odpadne vode.
82
Metode poučevanja in učenja:
Pristop temelji na samostojnem delu študenta
ob sodelovanju učiteljev (priprava na
seminarske naloge, predstavitev seminarskih
nalog, konzultacije z učitelji, priprava na izpit in
izpit).
Načini ocenjevanja:
Izpit je opravljen, če so pozitivno opravljene
vse naslednje obveznosti:
 seminarska naloga
 pisni izpit
 ustni izpit
Learning and teaching methods:
The approach is based on the student's own work in
cooperation with teachers (preparation for the
seminar, seminar presentations, consultations with
teachers, preparing for the exam and the exam).
Delež (v %) /
Weight (in %) Assessment:
Student has to pass successfully the
following obligations:
 individual paper
30
40
 written examination
30
 oral examination
Reference nosilca / Lecturer’s references:
KRIŽAN, Janja, PETRINIĆ, Irena, GORŠEK, Andreja, SIMONIČ, Marjana. Ultrafiltration of oil-in-water emulsion by
using ceramic membrane : Taguchi experimental design approach. Central European Journal of Chemistry, ISSN
1895-1066, Feb. 2014, vol. 12, iss. 2, str. 242-249
BAUMAN, Maja, KOŠAK, Aljoša, LOBNIK, Aleksandra, PETRINIĆ, Irena, LUXBACHER, Thomas. Nanofiltration
membranes modified with alkoxysilanes : surface characterization using zeta-potential. Colloids and surfaces. A,
Physicochemical and Engineering Aspects, ISSN 0927-7757. [Print ed.], 5. Apr. 2013, vol. 422, str. 110-117
VERLIEFDE, A. R. D., CORNELISSEN, E. R., HEIJMAN, S. G. J., PETRINIĆ, Irena, LUXBACHER, Thomas, AMY, Gary L.,
BRUGEN, B. van der, DIJK, J. C. van. Influence of membrane fouling by (pretreated) surface water on rejection of
pharmaceutically active compounds (PhACs) by nanofiltration membranes. Journal of membrane science, ISSN
0376-7388. [Print ed.], Mar. 2009, vol. 330, iss. 1/2, str. 90-103
83
Transportni pojavi v bioloških sistemih in tehnologija biomimetike
Predmet:
Course title:
UČNI NAČRT PREDMETA / COURSE SYLLABUS
Transportni pojavi v bioloških sistemih in tehnologija biomimetike
Transport phenomena in biological systems and biomimetic technology
Študijski program in stopnja
Study programme and level
Študijska smer
Study field
Letnik
Academic year
Semester
Semester
2.
Zimski
Autumn
Kemijska tehnika / 2. stopnja
Chemical Engineering / 2nd level
Vrsta predmeta / Course type:
Izbirni / Optional
Univerzitetna koda predmeta / University course code:
Predavanja
Lectures
Seminar
Seminar
Sem. vaje
Tutorial
15
Nosilec predmeta / Lecturer:
Jeziki /
Languages:
Lab. vaje
Laboratory
work
15
Teren. vaje
Field work
Samost. delo
Individ. work
ECTS
150
6
Claus Hélix-Nielsen
Predavanja / Lectures: angleščina / English
Vaje / Tutorial: angleščina / English
Pogoji za vključitev v delo oz. za opravljanje
študijskih obveznosti:
Osnovno znanje splošne in anorganske kemije,
matematike in fizike.
Prerequisits:
Vsebina:
Predmet zajema tri glavne teme z naslovi:
 Biomolekule (sestava beljakovin in membrane)
in njihovo delovanje
 Celice: lastnosti in delovanje izbranih celic,
celična mehanika
 Transport fluidov in osmozni pojavi v nano
območju, biomembrane in prenos snovi skozi
membrano
Content (Syllabus outline):
The course includes three main thematic topics:
 Biomolecules (protein and membrane
components) and their function.
 Cells: properties and function of selected cells,
cellular mechanics.
 Transport of fluidics and osmotics phenomenom
in nanoscale size, biomembranes and membrane
transport.

Computer Exercises:
Calculation of fluid transport and osmotic
phenomenon in nanoscale size of biological systems.
Project assignment.
Računalniške vaje:
Izračuni transportov fluidov in osmoznih pojavov v
nano območju bioloških sistemov.
Projektna naloga.
Basic knowledge of general and inorganic chemistry,
mathematics and physics.
84
Temeljni literatura in viri / Readings:
 Claus Hélix-Nielsen, Biomimetic membranes for sensor and separation applications. Chapters 2, 3, 4, 7,
and 9. Springer Verlag, 2012. http://link.springer.com/book/10.1007%2F978-94-007-2184-5.
Dodatna priporočena literatura:
 Julian Lewis, Peter Walter, Alexander Johnson, Keith Roberts, Martin Raff & Bruce Alberts, Molecular
Biology of the Cell. Chapters 3, 10 and 11. Garland Science, 2008.
 Rodney Cotterill, Biophysics – an Introduction. Chapters 5, 6, 8, and 11. Wiley, 2002.
Cilji in kompetence:
Predmet predstavi izbrane sodobne teme, ki
povezujejo področja med biofiziko, mikro in nanovelikostjo fizike. V Laboratoriju za vodno biofiziko
in membranske procese (LWB) bomo uvedli nove
raziskovalne dejavnosti. V beljakovinah, celicah,
biomembranah in organizmih se bodo proučevale
kompleksne biološke strukture in njihovo
delovanje. Obravnavani bodo nanotehnološki in
biomimetični pristopi za testiranje biofizikalnih
struktur in procesov.
Študenti bodo pridobili osnovna znanja in izkušnje
pri iskanju strokovne literature v nastajajočem
interdisciplinarnem področju, kar jim bo omogočilo
nadaljnje raziskovanje/nadgrajevanje z izvedbo
lastnih raziskovalnih projektov.
Objectives and competences:
The course introduces selected contemporary topics
at the interface between biophysics and micro- and
nanoscale physics. At the same time, research
activities at the Laboratory for Water Biophysics and
membrane processes (LWB) are introduced.
Complex biological structures and their function are
studied, ranging from proteins, cells, biomembranes
to organisms. Nanotechnological and biomimetic
approaches for probing biophysical structures and
processes will be discussed.
Participants will obtain the basic knowledge and
skills for understanding the research literature in an
emerging interdisciplinary field and will be able to
consider and perform future research projects of
their own.
Predvideni študijski rezultati:
Znanje in razumevanje:
Z osvojenimi cilji bo študent lahko:
• razumel in uporabljal podatkovne baze
biomolekurnih struktur in zaporedij
• pojasnil celično sestavo odgovorno za
mehanske lastnosti celic
• opredelil strukturne in funkcionalne elemente
biomembran
• obrazložil transportne pojave skozi
membrano, vključno z difuzijo, aktivnim
transportom, pospešenim transportom in
osmotskim transportom
• pojasnil osnovni koncept toka tekočine v
mikro-merilu
 bral, razumel in predstavil sodobne
interdisciplinarne raziskovalne članke s
področja biofizike, biotekočin in biomimetike
Intended learning outcomes:
A student who has met the objectives of the course
will be able to:
• Understand and use databases of bio-molecular
structures and sequences
• Explain the cellular constituents responsible for
mechanical properties of cells
• Explain defining structural and functional
elements of biomembranes
• Explain membrane transport phenomena
including barrier diffusion, active transport,
facilitated transport and osmotic transport
• Explain the basic concepts of fluid flow at the
micrometer scale
 Read, understand and present contemporary
interdisciplinary research articles in the field of
biophysics, biofluidics, and biomimetics.
85
Metode poučevanja in učenja:
Predavanja, učenjev skupinah na določenih
nalogah/problemih in pisanje poročil.
Learning and teaching methods:
Lectures, problem based learning in groups, and
writing report.
Delež (v %) /
Načini ocenjevanja:
Weight (in %) Assessment:
Izpit je opravljen, če so pozitivno opravljene vse
Student has to pass successfully the
naslednje obveznosti:
following obligations:
 Ustni izpit
 Oral exam
50
 Projektno poročilo
 Project report
50
Reference nosilca / Lecturer’s references:
Nielsen, C.H. Biomimetic membranes for sensor and separation applications. Anal. Bioanal. Chem. 395, 697-718,
2009.
Nielsen, C.,H. Protein-lipid interactions in Biological Membranes. In Bohr, H. (ed.) Handbook of Molecular
Biophysics, 329-358, Wiley-VC Berlin, Germany, 2009. ISBN-10: 3527407022.
Hélix-Nielsen, C. Biomimetic membranes for sensor and separation applications. Springer Verlag ISBN 978-94-0072183-8, 2012.
86
Novi biotehnološki pristopi in aplikacije
Predmet:
Course title:
UČNI NAČRT PREDMETA / COURSE SYLLABUS
Novi biotehnološki pristopi in aplikacije
Novel Biotechnological Approaches and Applications
Študijski program in stopnja
Study programme and level
Študijska smer
Study field
Letnik
Academic year
Semester
Semester
2.
Zimski
Autumn
Kemijska tehnika / 2. stopnja
Chemical Engineering / 2nd level
Vrsta predmeta / Course type:
Izbirni / Optional
Univerzitetna koda predmeta / University course code:
Predavanja
Lectures
Seminar
Seminar
Sem. vaje
Tutorial
15
Nosilec predmeta / Lecturer:
Jeziki /
Languages:
Lab. vaje
Laboratory
work
15
Teren. vaje
Field work
Samost. delo
Individ. work
ECTS
150
6
Martin Koller
Predavanja / Lectures: angleščina / English
Vaje / Tutorial: angleščina / English
Pogoji za vključitev v delo oz. za opravljanje
študijskih obveznosti:
Ni.
Prerequisits:
Vsebina:
Izbrana poglavja iz mikrobiologije in osnov
tehnologije čistih prostorov (Cleanroom)
 Mikrobiološki razvoj in mikrobiološka
sistematika; “Drevo življenja”
 Gibljivost mikrobov (kemotaksa, aerotaksa,
magnetotaksa, bički itd.
 Mikrobiološke strategije za pridobivanje
biomase in energije (autotrofni in heterotrofni
organizmi, metabolične poti itd.)
 Vloga mikrobov pri naravnem ciklu kemijskih
elementov (C, O, N, P, S)
 Antibiotiki: razredi, različni akcijski mehanizmi,
tveganja in izzivi
 Principi načrtovanja čistih prostorov (Cleanrooms): definicija, različni razredi in nivoji istih
prostorov
 Rizične skupine mikrobov: ravnanje in zakonski
predpisi
Content (Syllabus outline):
Selected Chapters of Microbiology and Basics of
Cleanroom Engineering
 Microbial evolution and microbial systematic;
Tree of Life
 Motility of microbes (chemotaxis, aerotaxis,
magnetotaxis, flagellates, etc.)
 Microbial strategies for biomass- and energy
generation (autotrophic and heterotrophic
organisms, metabolic pathways, etc.)
 The role of microbes in the natural cycles of the
chemical elements (C, O, N, P, S)
 Antibiotics: Classes, different mechanisms of
action, risks and challenges
 Principles of Cleanroom Engineering: Definition
and different classes and levels of cleanrooms
 Risk groups of microbes: Handling, Legislative
conditions
New Approaches to Industrial Biotechnology
None.
87
Novi pristopi k Industrijski biotehnologji (“Bela
biotehnologija”)
 Izbrani biotehnološki produkti narekujejo
uporabo industrijskih odpadkov in presežnih
materialov, kot npr. sirotke iz mlečne
industrije, stranskih produktov iz proizvodnje
biodizla, odpadnih maščob rastlinskega in
živalskega izvora, (ligno)celuloza
Podrobnosti: razpoložljivost surovin v
odvisnosti od globalne regijske in sezonske
razpoložljivosti, izzivi in posebnosti pri njihovi
pripravi in presnovi, ter perspektive tržnega
uvajanja produktov
 Poli(hidroksialkanoati) (PHA) kot biotehnologična alternativa za sodobno proizvedene
tehnomere (termoplaste in elastomere):
genetske, encimske, metabolične in tehnološke
osnove, tehnike; izzivi pri separacijah teh
materialov in njihova uporaba za specialne
produkte (farmacevtske, medicinske, agroindustrijske itd…)
- posebno poglavje: autotrofna, miksotrofna
in heterotrofna proizvodnja poli(hidroksialkanoatov) z izbranimi fototrofnimi mikrobi
- posebno poglavje: pilotna in industrijska
proizvodnja PHA iz različnih biogenih surovin;
primeri različnih globalnih regij
- posebno poglavje: novi procesno tehnološki
pristopi za proizvodnjo PHA za izboljšanje
kvalitete in kvantitete proizvodnje
biopolimerov (npr. večstopenjski kontinuirni
procesi) in razvoj novih vrst biogenih
tehnomerov, npr. blok polimerov
 Primarni in sekundarni produkti iz extremophile
archaea (pigmenti, specialni ogljikovodiki,
inertni citoplazmatski produkti, halocini)
 Prokariotski mikrobi s sposobnostjo tvorjenja
spor kot proizvajalci različnih ciljnih produktov
(biotehnološki aceton, izopropanol, nastanek
butanola, proizvodnja insekticidov z bacilli)
Podrobnosti: posebnosti gojenja takšnih sevov,
kinetične značilnosti tvorbe produktov,
prednosti in slabosti v primerjavi s kemijsko
proizvodnjo
 Biovodik kot nosilec prihodnje zelene energije:
Biotehnološka proizvodnja, izzivi, perspektiva in
primerjava z drugo, tretjo in četrto generacijo
biogoriv
 Napredne filtracijske tehnike za industrijske
biotehnološke aplikacije (membrane iz votlih
vlaken za mikro-, ultra-, nanofiltracijo in
reverzno ozmozo)
(White Biotechnology)
 Selected biotechnological products form the
application of industrial waste- and surplus
materials feedstock, namely: whey from dairy
industry, side streams from the biodiesel
production, waste lipids of phytal and animal
origin, (Ligno)cellulosics
Details: Availability of the raw materials in
dependence on the global region and seasonal
availability, challenges and particularities in
their upstream processing and conversion, and
perspectives of market penetration of the
products
 Poly(hydroxyalkanoates) (PHAs) as biotechnological alternative for contemporarily produced
technomers (thermoplasts and elastomers):
Genetic, enzymatic, metabolic and engineering
Fundamentals, techniques; challenges in
downstream processing of these materials, and
their application for bulk and niche products
(packaging, pharmaceutical, medical, agroindustrial, etc.).
- Special
section
about:
Autotrophic,
mixotrophic and heterotrophic production of
poly(hydroxyalkanoates)
by
selected
phototrophic microbes
- Special section about: Pilot- and industrial
scale production of PHA starting from
different biogenic feedstocks; case studies
from different global regions
- Special section about: New process
engineering aproaches for PHA production to
enhance quality and quantity of biopolymer
production
(e.g.
multistage-continuous
processes), and to design new types of
biogenic technomers (e.g. blockpolymers)
 Primary and secondary products from
extremophile archaea (pigments, special
carbohydrates, inert cytoplasmatic compounds,
halocins)
 Sporeforming prokaryotic microbes as producers
of various bulk- and niche products
(biotechnological acetone, isopropanol, butanol
formation, production of insecticides by Bacilli.
Details: Particularities in the cultivation of such
production strains; kinetic particularities of
product
formation,
advantages
and
disadvantages in comparison to chemical
production.
 Biohydrogen as a future-oriented »green energy
carrier«:
Biotechnological
production,
challenges, prospective, and comparison to
other 2nd, 3rd, and 4th generation biofuels.
 Advanced filtration techniques for large-scale
biotechnological application (Hollow fiber
88
Laboratorijske vaje:
 Splošno ravnanje z bioreaktorji
 Gojenje kvasovk v bioreaktorju (regulacija
procesa in analiza kinetike)
 Gojenje izbranega biopoliestra (PHA) za
proizvodnjo prokariontskih vrst v bioreaktorju
(regulacija in zaključni procesi za čiščenje
produkta, analiza kinetike)
 Gojenje fototrofnih mikroalg v fotobioreaktorju
(regulacija, analiza kinetike, zaključni procesi za
čiščenje olj iz mikroalg kot potencialne
surovine za biodizel 3. generacije)
 Določanje celične mase v tekočih kulturah
(centrifuguranje, filtracija, liofilizacija,
infrardeča bilanca itd.)
 Barvanje celic za ponazoritev organel in inkluzij
(jedra, spore, inertne citoplazemske inkluzije,
bički)
membranes for micro-, ultra-, nanofiltration and
reversed osmosis)
Labor work
 General handling of bioreactors
 Cultivation of yeast in bioreactor (together with
process control, and kinetic analysis)
 Cultivation of a selected biopolyester (PHA)
producing prokaryotic species in bioreactor
(together with process control, downstream
processing for product recovery, and kinetic
analysis)
 Cultivation of a selected phototrophic microalgal
species in photobioreactor (together with
process control,
kinetic
analysis,
and
downstream processing for recovery of
microalgal oil as potential 3rd-generation
biodiesel feedstock
 Determination of cell mass in liquid cultures
(centrifugation, filtration, lyophylization, infrared
balance etc.)
 Cell staining for visualization of organelles and
inclusions (nucleus, spores, inert cytoplasmatic
inclusions, flagella)
Temeljni literatura in viri / Readings:
 Scriptum provided by lecturer
 Selected original (primary and secondary) literature provided by lecturer (also own publications)
 Koller, M.: Designs of Closed Photobioreactors for Algal Cultivation. – in: Algal Biorefeneries Vol. II
(submitted; publication expected in 2015) (Springer; book chapter)
Dodatna priporočena literatura:
 Koller, M.; Salerno, A.; Braunegg, G. (2013): Polyhydroxyalkanoates: Basics, Production and
Applications of Microbial Biopolyesters. - book: Bio-based Plastics: Materials and Applications, pp. 137
– 170 (Wiley)
 Koller, M.; Salerno, A.; Muhr, A.; Reiterer, A.; Braunegg, G. (2013): Polyhydroxyalkanoates:
Biodegradable polymeric materials from renewable resources. Materiali in Tehnologije = Materials and
Technology 47(1), 5–12
Cilji in kompetence:
Študent bo pridobil naslednja znanja:
 pilotna in idustrijska biotehnologija za velikokapacitetne in nišne produkte
 obnovljive surovine za industrijske
bioproizvode in uporaba industrijskih
presežkov v biotehnologiji
 analize kinetike na osnovi podatkov,
pridobljenih v bioprocesu in končna ocena
procesa
 zaključni procesi za pridobivanje industrijsko
pomembnih intracelularnih bioproduktov.
Objectives and competences:
The main objective is devoted to knowledge in
 Pilot- and Industrial scale biotechnology for bulkand niche products
 Renewable raw materials for industrial
bioprodcts with special emphasis on industrial
surplus streams to be upgraded to feedstocks for
biotechnology
 Kinetic analysis of own elaborated raw data from
bioprocess and final process evaluation
 Downstream processing for recovery of
industrially relevant intracellular bioproducts
89
Predvideni študijski rezultati:
Znanje in razumevanje:
 Vrste bioproduktov in substratov ter mikrobov
za njihovo proizvodnjo
 Mikrobne strategije za proizvodnjo biomase in
energije
 Osnovno znanje o antibiotikih
 Gojenje različnih mikrobov v laboratorijskem
bioreaktorju, spremljanje, nadzor in ocean
vrednotenje procesa
Intended learning outcomes:
Knowledge and Understanding:
 Range of different bioproducts and accessible
substrates and microbes to produce them
 Microbial strategies for biomass- and energy
production
 Basic knowledge about antibiotics
 Performing cultivation of different microbes in
laboratory bioreactors with accompanying
process monitoring and subsequent process
evaluation
Prenesljive/ključne spretnosti in drugi atributi:
 razumevanje prednosti, slabosti in izzivov
bioproizvodnje
 razumevanje celovitih okoljskih in ekonomskih
vplivov kemijske in biokemijske proizvodnje
 razumevanje različnih zahtev različnih
mikrobov
 seznanitev z industrijsko pomembnimi
mikroorganizmi.
Transferable/Key Skills and other attributes:
 Understanding the advandages, drawbacks, and
challenges of bio-based production.
 Understanding the holistic environmental and
economic impacts of chemical vs. biochemical
production strategies
 Understanding different requirements of
different microbes
 Getting familiar with industrially relevant
microorganisms
Metode poučevanja in učenja:
 predavanja
 samostojno seminarsko delo za končno ustno
predstavitev laboratorijskih rezultatov
(skupinsko ali posamezno)
 samostojno seminarsko delo za ustno
predstavitev izbrane izvirne literature
(skupinsko ali posamezno)
 samostojno učenje
Learning and teaching methods:
 Lectures
 Independent seminar work for final oral
presentation of laboratory results (group or
single)
 Independent seminar work for oral presentation
of selected original literature (group or single)
 Self-learning
Delež (v %) /
Načini ocenjevanja:
Weight (in %) Assessment:
Izpit je opravljen, če so pozitivno opravljene vse
Student has to pass successfully the
naslednje obveznosti:
following obligations:
25
 Pisni izpit
 Final written examination
12,5
 Ustna predstavitev laboratorijskih
 Oral presentation of own laboratory
rezultatov
results
 Ustna predstavitev izbranih tem
 Oral presentation on selected topics
12,5
25
 Izvedba kinetične analize eksperimentalnih
 Evaluation of kinetic analysis of own
podatkov, pridobljenih v izvedenem
experimental raw data from the
bioprocesu
accomplished bioprocesses
25
 Aktivno sodelovanje
 Active collaboration
Reference nosilca / Lecturer’s references:
Koller, M.; Chiellini, E., Braunegg, G. (2015): Study on the production and re-use of poly(3-hydroxybutyrate-co-3hydroxyvalerate) and extracellular polysaccharide by the archaeon Haloferax mediterranei strain DSM 1411
Chemical and Biochemical Engineering Quarterly 29(2); in press.
Koller, M.; Muhr, A., Braunegg, G. (2014): Microalgae as versatile cellular factories. Algal Research 6(A), 53-63.
Koller, M.; Bona, R.; Braunegg, G.; Hermann, C.; Horvat, P.; Kroutil, M.; Martinz, J.; Neto, J.; Varila, P.; Pereira, L.
(2005): Production of polyhydroxyalkanoates from agricultural waste and surplus materials. Biomacromolecules
6(2), 561–565.
90
FP 7 EU-Project ANIMPOL ‘Biotechnological conversion of carbon containing wastes for eco-efficient production of
high added value products’ (Grant number 245084): Coordinator and Person in charge for the administrative,
financial, scientific and technical aspects of the project (2010-2013): Most relevant references:
Muhr, A.; Rechberger, E. M.; Salerno, A.; Reiterer, A.; Schiller, M.; Kwicien, M.; Adamus, G.; Kowalczuk, M.;
Strohmeier, K.; Schober, S.; Mittelbach, M.; Koller, M. (2013): Biodegradable latexes from animal-derived waste:
Biosynthesis and characterization of mcl-PHA accumulated by Ps. citronellolis. Reactive & Functional Polymers
73(10), 1391–1398
Shahzad, K.; Kettl, K.-H.; Koller, M.; Titz, M.; Schnitzer, H.; Narodoslawsky, M. (2013): Comparison of ecological
footprint for biobased PHA production from animal residues utilizing different energy resources. Clean
Technologies and Environmental Policy 15(3), 525–536
91
Encimske tehnologije
Predmet:
Course title:
UČNI NAČRT PREDMETA / COURSE SYLLABUS
Encimske tehnologije
Enzyme Technologies
Študijski program in stopnja
Study programme and level
Kemijska tehnika / 2. stopnja
Chemical Engineering / 2nd level
Študijska smer
Study field
Biokemijska tehnika
Biochemical Engineering
Vrsta predmeta / Course type:
Letnik
Academic year
2.
Semester
Semester
zimski
Autumn
Izbirni / Optional
Univerzitetna koda predmeta / University course code:
Predavanja
Lectures
15
Seminar
Seminar
Nosilec predmeta / Lecturer:
Jeziki /
Languages:
Sem. vaje
Tutorial
Lab. vaje
Labor work
15
Teren. vaje
Field work
Samost. delo
Individ. work
150
ECTS
6
Maja Leitgeb
Predavanja / Lecture: slovenski / Slovene
Vaje / Tutorial: slovenski / Slovene
Pogoji za vključitev v delo oz. za opravljanje
študijskih obveznosti:
Potrebno je znanje iz bioseparacijske tehnike in
biokatalize ter industrijske mikrobiologije.
Prerequisites:
Vsebina:
Izolacija in priprava encimov.
Imobilizacija.
Uporaba encimov (detergenti, tekstilije, papir,
živalska krma).
Encimi kot biokatalizatorji (osnovne kemikalije, fine
kemikalije, hrana, farmacevtske učinkovine).
Farmacevtska aplikacija biokatalize (inhibicija
encimov za boj proti boleznim, specifične
biokatalizne reakcije v farmaciji).
Sintetični encimi.
Content (Syllabus outline):
Isolation and preparation of enzymes.
Imobilization.
Application of enzymes (detergents, textilles, pulp
and paper, animal feed).
Application of enzymes as biocatalysts (basic
chemicals, fine chemicals, food, pharmaceuticals).
Pharmaceutical application of biocatalysis (enzyme
inhibition for the fight against disease, specific
biocatalytic reactions in pharma).
Artificial enzymes.
Laboratorijske vaje na konkretnem primeru
biokatalizirane proizvodje osnovnih in finih
kemikalij ter postopka priprave encimov.
Laboratory work on the case of biocatalytic
production of basic and fine chemicals, as well as on
preparation of enzymes.
Knowledge of bioseparation processes and
biocatalysis and industrial microbiology is needed.
92
Temeljni literatura in viri / Textbooks:
 S. Bommarius, B. R. Riebel-Bommarius, Biocatalysis: Fundamentals and Applications, 1st ed., WileyVCH; Darmstadt, 2004.
 Liese, K. Seelbach, C. Wandrey, Industrial Biotransformations, Wiley-VCH, Weinheim, 2000.
Dodatna priporočena literatura:
 J. A. Tao, R. J. Kazlauskas, Biocatalysis for Green Chemistry and Chemical Process Development, Wiley,
ISBN: 978-0-470-43778-0, 2011.
 M. C. Flickinger, Encyclopedia of Industrial Biotechnology, Bioprocess, Bioseparation, and Cell
Technology , 7 Volume Set, Wiley, ISBN: 978-0-471-79930-6, 2010.
 A. Illanes, L. Wilson, C. Vera, Problem Solving in Enzyme Biocatalysis, Wiley, ISBN: 978-1-118-34171-1,
2013.
Cilji in kompetence:
Pregled metod izolacije in čiščenja encimov ter
aplikacija posameznih encimov v
biotransformacijah.
Objectives and competences:
Overview of enzyme isolation and purification
methods and application of enzymes in
biotransformations.
Predvideni študijski rezultati:
Znanje in razumevanje:
Poznavanje proizvodnje encimov, njihove
stabilnosti in produktivnosti ter uporabe v
biosintezi.
Intended learning outcomes:
Knowledge and Understanding:
Knowledge of enzyme production, their stability and
productivity, as well as their application in
biosynthesis.
Prenesljive/ključne spretnosti in drugi atributi:
Predmet se dopoljnjuje z ostalimi vsebinami na
smeri Biokemijska tehnika.
Transferable/Key Skills and other attributes:
The subject is related to the other subjects on the
study field Biochemical engineering.
Metode poučevanja in učenja:
Predavanja v učilnici, ki je opremljena z avdiovizualnimi pripomočki.
Individualna priprava seminarskih nalog s
predstavitvijo in diskusijo.
Laboratorijsko delo na izbranem primeru.
Learning and teaching methods:
Lectures in lecture room, equipped with audio-visual
equipment
Individual preparation of seminars and their
presentation with discussion.
Laboratory work on a selected case.
Načini ocenjevanja:
Izpit je opravljen, če so pozitivno
opravljene vse naslednje obveznosti:
- laboratorijsko delo
- seminarska naloga
- ustni izpit
Delež (v %) /
Weight (in %)
30
30
40
93
Assessment:
Student has to pass successfully the
following obligations:
- laboratory work
- seminary work
- oral examination
Reference nosilca / Lecturer’s references:
KNEZ, Željko, KAVČIČ, Sabina, GUBICZA, László, BÉLAFI-BAKÓ, Katalin, NÉMETH, Gergely, PRIMOŽIČ, Mateja,
LEITGEB, Maja. Lipase-catalyzed esterification of lactic acid in supercritical carbon dioxide. The Journal of
supercritical fluids, ISSN 0896-8446. 2012, 66, 192-197, doi: 10.1016/j.supflu.2011.11. [COBISS.SI-ID 15598102]
ŠULEK, Franja, PÉREZ FERNÁNDEZ, Daniel, KNEZ, Željko, LEITGEB, Maja, SHELDON, Roger A. Immobilization of
horseradish peroxidase as crosslinked enzyme aggregates (CLEAs). Process biochemistry, ISSN 1359-5113, 2011, 46
(3), 765-769, doi: 10.1016/j.procbio.2010.12.001. [COBISS.SI-ID 14712598]
CSANÁDI, Zsófia, BÉLAFI-BAKÓ, Katalin, SZENTGYÖRGYI, Eszter, GUBICZA, László, KNEZ, Željko, LEITGEB, Maja.
Enzymatic esterification of glycerol and stearic acid in non-conventional media. Acta chimica slovenica, ISSN 13180207. 2010, 57 (1), 244-249. COBISS.SI-ID 14029590]
ŠULEK, Franja, KNEZ, Željko, LEITGEB, Maja. Immobilization of cholesterol oxidase to finely dispersed silica-coated
maghemite nanoparticles based magnetic fluid. Applied Surface Science, ISSN 0169-4332. 2010, 256 (14), 45964600. [COBISS.SI-ID 14055446]
THOREY, Paul, KNEZ, Željko, LEITGEB, Maja. Alcohol dehydrogenase in non-aqueous media using high-pressure
technologies : reaction set-up and deactivation determination. Journal of chemical technology and biotechnology,
ISSN 0268-2575. 2010, 85, 1011-1016. [COBISS.SI-ID 14291222]
94
Sodobna biokataliza
Predmet:
Course title:
UČNI NAČRT PREDMETA / COURSE SYLLABUS
Sodobna biokataliza
Modern biocatalysis
Študijski program in stopnja
Study programme and level
Kemijska tehnika / 2. stopnja
Chemical Engineering / 2nd level
Študijska smer
Study field
Biokemijska tehnika
Biochemical Engineering
Vrsta predmeta / Course type:
Letnik
Academic year
2.
Semester
Semester
zimski
Autumn
Izbirni / Optional
Univerzitetna koda predmeta / University course code:
Predavanja
Lectures
15
Seminar
Seminar
Nosilec predmeta / Lecturer:
Jeziki /
Languages:
Sem. vaje
Tutorial
Lab. vaje
Labor work
15
Teren. vaje
Field work
Samost. delo
Individ. work
150
ECTS
6
Maja Leitgeb
Predavanja / Lecture: slovenski / Slovene
Vaje / Tutorial: slovenski / Slovene
Pogoji za vključitev v delo oz. za opravljanje
študijskih obveznosti:
Potrebno je znanje iz bioseparacijske tehnike in
biokatalize ter industrijske mikrobiologije.
Prerequisites:
Vsebina:
Encimi v organskih topilih (prednosti, bifazne
reakcije, separacija, stabilnost encimov,
selektivnost encimov).
Prednosti biokatalize v organskih topilih.
Korelacija med delovanjem encimov in parametri
topila (variacija hidrofobnosti – log P,
enantioselektivnost in polarnost topila ter
hidrofobost).
Optimalno rokovanje z encimi v organskih topilih.
Novejši reakcijski mediji za biokatalizo (substrat kot
topilo, superkritični fluidi, ionske tekočine,
emulzije, mikroemulzije, tekoči kristali).
Topilo kot parameter za optimiranje reakcije
(»medium engineering«).
Content (Syllabus outline):
Enzymes in organic solvents (advantages, biphasic
reactions, separation, enzyme stability, selectivity of
enzymes).
Advantages of biocatalysis in organic solvents.
Correlation between enzyme performance and
solvent parameters (variation of hydrophobicity –
log P, enantioselectivity and solvent polarity and
hydrophobicity).
Optimal handling of enzymes in organic solvents.
Novel reaction media for biocatalysis (substrate as a
solvent, supercritical fluids, ionic liquids, emulsions,
microemulsions, liquid crystals).
Solvent as a parameter for reaction optimization
(»medium engineering).
Laboratorijske vaje iz področja encimsko
kataliziranih reakcij v nekonvencionalnih medijih,
npr. v plinih visoke gostote, ionskih tekočinah, …
Laboratory work in the field of enzymatic reactions
in nonconventional media, e.g. supercritical fluids,
ionic liquids, etc.
Knowledge of bioseparation processes, biocatalysis
and industrial microbiology is needed.
95
Temeljni literatura in viri / Textbooks:
 A. S. Bommarius, B. R. Riebel-Bommarius, Biocatalysis: Fundamentals and Applications, 1st ed., WileyVCH; Darmstadt, 2004.
 K. Faber, Bio-transformations in Organic Chemistry, 6th ed., Springer-Verlag, Berlin, 2011.
Dodatna priporočena literatura:
 P.G. Jessop, W. Leitner, Chemical Synthesis Using Supercritical Fluids, Wiley-VCH, Weinheim, online
2007.
 P. Wasserscheid, T. Welton, Ionic Liquids in Synthesis, 2nd ed., Wiley-VCH, Weinheim, 2007.
Cilji in kompetence:
Pregled možnih alternativnih topil za biokatalitične
transformacije.
Objectives and competences:
Overview of possible alternative solvents for
biocatalytical transformations.
Predvideni študijski rezultati:
Znanje in razumevanje:
Zmožnost načrtovanja biokataliziranih reakcij v
topilih, ki niso voda.
Intended learning outcomes:
Knowledge and Understanding:
Design of biocatalytical reactions in solvents, others
than water.
Prenesljive/ključne spretnosti in drugi atributi:
Predmet se dopoljnjuje z ostalimi vsebinami na
smeri Biokemijska tehnika.
Transferable/Key Skills and other attributes:
The subject is related to the other subjects on the
study field Biochemical engineering.
Metode poučevanja in učenja:
Predavanja v učilnici, ki je opremljena z avdiovizualnimi pripomočki.
Individualna priprava seminarskih nalog s
predstavitvijo in diskusijo.
Laboratorijsko delo na izbranem primeru.
Learning and teaching methods:
Lectures in a lecture room, equipped with audiovisual equipment
Individual preparation of seminars and their
presentation with discussion.
Laboratory work on selected case.
Načini ocenjevanja:
Izpit je opravljen, če so pozitivno
opravljene vse naslednje obveznosti:
- laboratorijske vaje
- ustni izpit
Delež (v %) /
Weight (in %)
40
60
Assessment:
Student has to pass successfully the
following obligations:
- laboratory work
- oral examination
Reference nosilca / Lecturer’s references:
KNEZ, Željko, KAVČIČ, Sabina, GUBICZA, László, BÉLAFI-BAKÓ, Katalin, NÉMETH, Gergely, PRIMOŽIČ, Mateja,
LEITGEB, Maja. Lipase-catalyzed esterification of lactic acid in supercritical carbon dioxide. The Journal of
supercritical fluids, ISSN 0896-8446. 2012, 66, 192-197, doi: 10.1016/j.supflu.2011.11. [COBISS.SI-ID 15598102]
CSANÁDI, Zsófia, BÉLAFI-BAKÓ, Katalin, SZENTGYÖRGYI, Eszter, GUBICZA, László, KNEZ, Željko, LEITGEB, Maja.
Enzymatic esterification of glycerol and stearic acid in non-conventional media. Acta chimica slovenica, ISSN 13180207. 2010, 57 (1), 244-249. COBISS.SI-ID 14029590]
THOREY, Paul, KNEZ, Željko, LEITGEB, Maja. Alcohol dehydrogenase in non-aqueous media using high-pressure
technologies : reaction set-up and deactivation determination. Journal of chemical technology and biotechnology,
ISSN 0268-2575. 2010, 85, 1011-1016. [COBISS.SI-ID 14291222]
KAVČIČ, Sabina, KNEZ, Željko, LEITGEB, Maja. Antimicrobial activity of n-butyl lactate obtained via enzymatic
esterification of lactic acid with n-butanol in supercritical trifluoromethane. The Journal of supercritical fluids, ISSN
0896-8446. 2014, 85, 143-150, doi: 10.1016/j.supflu.2013.11.003. [COBISS.SI-ID 17392406]
96
Farmacevtske učinkovine
Predmet:
Course title:
UČNI NAČRT PREDMETA / COURSE SYLLABUS
Farmacevtske učinkovine
Active Pharmaceutical Ingredients
Študijski program in stopnja
Study programme and level
Kemijska tehnika / 2. stopnja
Chemical Engineering / 2nd level
Študijska smer
Study field
Biokemijska tehnika
Biochemical Engineering
Vrsta predmeta / Course type:
Letnik
Academic year
2.
Semester
Semester
zimski
Autumn
Izbirni / Optional
Univerzitetna koda predmeta / University course code:
Predavanja
Lectures
15
Seminar
Seminar
Nosilec predmeta / Lecturer:
Jeziki /
Languages:
Sem. vaje
Tutorial
Lab. vaje
Labor work
15
Teren. vaje
Field work
Samost. delo
Individ. work
150
ECTS
6
Igor Simonič
Predavanja / Lecture: slovenski / Slovene
Vaje / Tutorial: slovenski / Slovene
Pogoji za vključitev v delo oz. za opravljanje
študijskih obveznosti:
Pogojev ni.
Prerequisites:
Vsebina:
- Farmacevtske učinkovine – neformulirana
zdravila; klasifikacije in terminologija.
- Ekonomski, socialni in strateški vidiki zdravil oz.
farmacevtskih učinkovin.
- Posebne zahteve in predpisi – učinkovitost,
varnost; sistemi kakovosti, dobre prakse v
razvoju, proizvodnji in kontroli farmacevtskih
učinkovin, validacijske tehnologije;
registracijske zahteve in dokumentacija.
- Pomen in vplivi fizikalno-kemijskih lastnosti na
učinkovitost in varnost; specifikacije kakovosti;
vsebnost, čistota, viri in vrste nečistot, strategije
obvladovanja nečistot, fizikalni in drugi
parametri, stabilnost.
- Principi razvoja proizvodnih in kontrolnih
tehnologij za farmacevtske učinkovine.
- Trendi v razvoju in proizvodnji farmacevtskih
učinkovin.
- Principi, značilnosti in pomen patentne zaščite
Content (Syllabus outline):
- Active pharmaceutical ingridients (API) –
nonformulated drugs; clasifications and
terminology.
- Economic, social and strategic aspects of drugs,
including API.
- Specific requirements and regulations – efficacy
and safety; quality systems, good practices in
development, production and quality control of
API, validation technologies; requirements for
registrations and documentation.
- Significance of physico-chemical parameters on
efficacy and safety; quality specifications; assay,
purity, sources and types of impurities, strategies
of mastering impurities, physical and other
parameters, stability.
- Principles of development of production and
quality control technologies for API.
- Trends in development and production of API.
- Principles, characteristics and significance of
None.
97
za farmacevtske učinkovine.
- Biotehnološke – klasične in rekombinantne,
sintetske in polsintetske učinkovine – značilni
primeri učinkovin in tehnologij; značilni
terapevtski in strukturni tipi.
patent protection of API.
- Biotechnological – classic and recombinant,
synthetic and semisynthetic API – characteristic
examples of substances and technologies;
characteristic therapeutic and structural types.
Temeljni literatura in viri / Textbooks:
 B. Štrukelj (ur.), J. Kos (ur.), Biološka zdravila: od gena do učinkovine, Slovensko farmacevtsko društvo,
Ljubljana, 2007.
Dodatna priporočena literatura:
 J. J. Li, D. S. Johnson, D. Sliskovic, B. D. Roth: Contemporary drug synthesis, John Wiley & Sons, Inc.,
Hoboken, New Jersey, 2004.
 O. Repič: Principles of process research and chemical development in the pharmaceutical industry,
John Wiley & Sons, Inc., New York, Chichester, Weinheim, Brisbane, Singapore, Toronto, 1998.
 M. M. Amiji, B. J. Sandmann: Applied physical pharmacy, McGraw-Hill Co. Inc., New York, 2003.
 European Pharmacopoeia, 4th Edition, EDQM, Strasbourg, 2004 (in druge izdaje ter dodatki).
Cilji in kompetence:
Študent spozna in razume specifične zahteve za
farmacevtske učinkovine ter multidisciplinarnost
obvladovanja tega področja; pridobi ključna znanja
za načrtovanje in razvoj proizvodnih in kontrolnih
tehnologij ter obvladovanje proizvodnje
farmacevtskih učinkovin. Usposobi se za delo v
timih s strokovnjaki na področju zdravil.
Objectives and competences:
Student acknowledges and understands specific
requirements for API and multidisiplinariness of the
field; acquires crucial expertise for planning and
developing production and quality control
technologies, as well as mastering API production.
Student gets qualified for team work in the field of
drugs.
Predvideni študijski rezultati:
Znanje in razumevanje:
Študent pozna osnovno terminologijo in
klasifikacije, ključne strukturne in terapevtske tipe
učinkovin ter značilne tehnologije. Pozna principe
in postopke razvoja tehnologij za učinkovine.
Razume pomen in medsebojne vplive parametrov
kakovosti in jih zna specificirati. Razume principe
sistemov kakovosti v razvoju, kontroli kakovosti in
proizvodnji. Pozna osnovne predpise za učinkovine
ter osnove zaščite intelektualne lastnine in pomen
za delo na področju zdravil.
Intended learning outcomes:
Knowledge and Understanding:
Student is familiar with basic terminology and
clasifications, crucial structural and therapeutic
types of API, as well as characteristic technologies;
knows principles and procedures of production and
quality control technologies development for API.
Uderstands signifiacance and correlations of quality
parameters, and is familiar with approaches to
determine them. Student understands principles of
quality sistems in development, quality control and
production of API, and is aware of relevant
regulations, as well as of IPR and its relevance for
working in the field.
Prenesljive/ključne spretnosti in drugi atributi:
Študent razvije sposobnost integracije znanj ter
reševanja kompleksnih interdisciplinarnih
problemov.
Transferable/Key Skills and other attributes:
Student develops ability to integrate his knowledge,
and to solve complex interdisciplinary problems.
Metode poučevanja in učenja:
Predavanja, seminarske vaje, projektno delo.
Learning and teaching methods:
Lectures, tutorial and project work.
98
Načini ocenjevanja:
Izpit je opravljen, če so pozitivno
opravljene vse naslednje obveznosti:
- projektno poročilo
- pisni izpit
Delež (v %) /
Weight (in %)
50
50
Assessment:
Student has to pass successfully the
following obligations:
- project report
- written examination
Reference nosilca / Lecturer’s references:
ŠTEFANIČ PETEK, Alenka, JAPELJ, Miha. Synthesis of cephalosporin derivatives with different 3'-nitrogen
heterocyclic substituents. Acta pharmaceutica, ISSN 1330-0075, 2000, vol. 50, no. 1, str. 17-27, ilustr. [COBISS.SI-ID
22536709]
JAPELJ, Miha. Significance of research and development in the pharmaceutical industry : Pharmaceutical company
KRKA, Slovenia, as an example. V: KORNHAUSER FRAZER, Aleksandra (ur.), DASILVA, Edgar (ur.), SAJOVIC, Irena
(ur.). Biotechnological intellectual property at universities : scientific, technological, economic, legal and ethical
aspects : proceedings of the Workshop - Expert Meeting ICCS, Ljubljana, 21 - 24 February 2001. Ljubljana:
Slovenian National Commission for Unesco: International Centre for Chemical Studies (ICCS), 2001, str. 55-57.
[COBISS.SI-ID 1157980]
ČASAR, Zdenko, LORCY, Dominique, ROBERT, Albert, MAJCEN LE MARECHAL, Alenka, JAPELJ, Miha. Towards
diselenadiazafulvalenes : synthesis of precursors. V: Slovenski kemijski dnevi 2000, Maribor, 28. in 29. september
2000. GLAVIČ, Peter (ur.), BRODNJAK-VONČINA, Darinka (ur.). Zbornik referatov s posvetovanja. Maribor: FKKT,
2000, del 1, str. 92-97. [COBISS.SI-ID 5690646]
FUJS, Štefan, KUŠČER, Enej, PETKOVIĆ, Hrvoje, SLADIČ, Gordan, GASPARIČ, Aleš. Process for production of lipstatin
and microorganisms therefore : European patent application : EP 2 141 236 A1 : application no. 08012016.5.
München: Europäisches Patentamt: = European Patent Office: = Office européen des brevets, 06.01.2010.
[COBISS.SI-ID 3746168]
GASPARIČ, Aleš, SLADIČ, Gordan, BENIČKI-ŠVAGELJ, Neda, PELKO, Mitja, RASPOR, Peter, PETKOVIĆ, Hrvoje, FUJS,
Štefan. Fermentative production of lipstatin : patent : EP 2019869 (B1), 2011-03-02. Paris: European Patent Office,
2011. 16 str., ilustr. [COBISS.SI-ID 3890296]
SLADIČ, Gordan, URUKALO, Matilda, KIRN, Matjaž, LEŠNIK, Urška, MAGDEVSKA, Vasilka, BENIČKI-ŠVAGELJ, Neda,
PELKO, Mitja, GASPARIČ, Aleš, RASPOR, Peter, POLAK, Tomaž, FUJS, Štefan, HOSKISSON, Paul A., PETKOVIĆ, Hrvoje.
Identification of lipstatin-producing ability in Streptomyces virginiae CBS 314.55 using dereplication approach.
Food technology and biotechnology, ISSN 1330-9862, 2014, vol. 52, no. 3, str. 276-284. [COBISS.SI-ID 4372088]
99
Farmacevtska tehnika
Predmet:
Course title:
UČNI NAČRT PREDMETA / COURSE SYLLABUS
Farmacevtska tehnika
Pharmaceutical Technology
Študijski program in stopnja
Study programme and level
Kemijska tehnika / 2. stopnja
Chemical Engineering / 2nd level
Študijska smer
Study field
Biokemijska tehnika
Biochemical Engineering
Vrsta predmeta / Course type:
Letnik
Academic year
2.
Semester
Semester
zimski
Autumn
Izbirni / Optional
Univerzitetna koda predmeta / University course code:
Predavanja
Lectures
15
Seminar
Seminar
Nosilec predmeta / Lecturer:
Jeziki /
Languages:
Sem. vaje
Tutorial
Lab. vaje
Labor work
15
Teren. vaje
Field work
Samost. delo
Individ. work
150
ECTS
6
Željko Knez
Predavanja / Lecture: slovenski / Slovene
Vaje / Tutorial: slovenski / Slovene
Pogoji za vključitev v delo oz. za opravljanje
študijskih obveznosti:
Znanje iz splošne kemije, analizne in fizikalne
kemije. Osnove iz mehanike fluidov in prenosnih
pojavov.
Prerequisites:
Knowledge on basic chemistry, analytical and
physical chemistry. Basics of fluid mechanics and
mass transfer.
Vsebina:
Farmacevtsko tehnološke operacije:
 fizikalno kemijske osnove pri načrtovanju
farmacevtske oblike (difuzija, adhezija,
kohezija, absorpcija, porazdelitev in
sproščanje, prenos snovi idr.),
 osnovne tehnološke operacije (mešanje,
mletje, postopki s superkritičnimi fluidi,
filtriranje, suspendiranje, steriliziranje,
liofiliziranje idr.),
 splošni vidiki pri načrtovanju farmacevtske
oblike (stabilnost in stabilizacija,
nekompatibilnosti, materiali in postopki za
embalažo, sterilizacija),
 razvite farmacevtske operacije,
 stabilnost zdravil.
Content (Syllabus outline):
Pharmaceutical technology operations:
 Physico-chemical basics of designing
pharmaceutical forms (diffusion, adhesion,
cohesion, absorbtion, distribution and
elimination of drugs, mass transfer and
others),
 Basic technology operations (mixing, grinding,
processes with supecritical fluids, filtration,
suspension, sterilization, liophilization and
others),
 Basic aspects for designing pharmaceutical
forms (stability and stabilization,
uncompatibility, materials and processes for
packaging, sterilization),
 Advanced pharmaceutical operations,
 Drug stability.
Farmacevtske oblike:
Pharmaceutical forms:
100






teoretične osnove farmacevtskih oblik kot
aplikacijskega in disperzijskega sistema
(osnovne in pomožne substance pri
načrtovanju farmacevtskih oblik),
statične metode pri načrtovanju farmacevtkih
oblik,
osnove biofarmacije,
farmacevstke oblike: trdne, poltrdne, tekoče,
plinaste (oblike za inhaliranje), rastlinski
izvlečki idr.,
sodobne oblike zdravil in tendenca razvoja
(terapevtski sistemi, potencialne oblike
zdravil).




Laboratorijske vaje:
Študentje spoznajo osnovne farmacevtsko
tehnološke operacije (mešanje, mletje, drobljenje,
postopki s superkritičnimi fluidi, kompaktiranje,
emulgiranje…) in sodobno načrtovanje,
oblikovanje in vrednotenje trdnih oblik s
poudarkom na izboru pomožnih snovi.
Theoretical basics of pharmaceutical forms as
an application and dispersion system (basic
and auxiliary substances at design of
pharmaceutical forms),
Static methods for designing pharmaceutical
forms,
Basics of biopharmacy,
Pharmaceutical forms: solids, semi-solids,
liquids, gasses (inhalation forms), natural
material extracts and others,
Modern forms of pharmaceutics and
development tendency (therapeutic systems,
potential pharmaceutical forms).
Laboratory work:
Students
become
familiar
with
basic
pharmaceutical technological operations (mixing,
grinding, crushing, processes with supercritical
fluids, compaction, emulsification,…) and modern
designing, formulation and evaluation of solid
forms with emphasis on suppository substance
selection.
Temeljni literatura in viri / Textbooks:
 Voigt R., Pharmazeutische Technologie für Studium und Beruf, 11., durchgesehene und ergänzte
Auflage 2010. XXIII, 746 S., 317 s/w Abb., 110 s/w Tab., gebunden, Deutscher Apotheker Verlag, ISBN
978-37692-5003-9, 2010.
Dodatna priporočena literatura:
 Roshni L. Dutton, Jeno M. Scharer, Jeno M. Scharer, Advanced Technologies for Biopharmaceutical
Processing, Blackwell Pub Professional, ISBN-10: 0813805171, 2006.
Cilji in kompetence:
Znanje o novih materialih, tehnoloških pristopih in
farmacevtskih oblikah.
Objectives and competences:
Knowledge on new materials,
approaches in pharmaceutical forms.
Predvideni študijski rezultati:
Znanje in razumevanje:
Znanje s področja osnovnih tehnoloških operacij in
formuliranja farmacevtskih oblik.
Prenesljive/ključne spretnosti in drugi atributi:
Vsebina predmeta je povezana z ostalimi predmeti
na smeri Biokemijska tehnika.
Intended learning outcomes:
Knowledge and Understanding:
Knowledge in the field of basic technological
operations and formulation of pharmaceutical
forms.
Transferable/Key Skills and other attributes:
The subject is connected to other subjects in the
option Biochemical engineering.
Metode poučevanja in učenja:
- predavanja
- laboratorijske vaje
Learning and teaching methods:
- lectures
- laboratory work.
101
technology
Načini ocenjevanja:
Izpit je opravljen, če so pozitivno
opravljene vse naslednje obveznosti:
- laboratorijske vaje
- pisni izpit
- ustni izpit
Delež (v %) /
Weight (in %)
10
50
40
Assessment:
Student has to pass successfully the
following obligations:
- laboratory work
- written examination
- oral examination
Reference nosilca / Lecturer’s references:
VERONOVSKI, Anja, NOVAK, Zoran, KNEZ, Željko. Synthesis and use of organic biodegradable aerogels as drug
carriers. Journal of biomaterials science, Polymer edition, ISSN 0920-5063, 2012, vol. 23, no. 7, str. 873-886.
LEITGEB, Maja, PRIMOŽIČ, Mateja, KNEZ, Željko. Biocompatible nanomaterials : synthesis, characterization and
applications. V: ACKLIN, Beate (ur.), LAUTENS, Edon (ur.). Magnetic nanoparticles : properties, synthesis and
applications, (Physics research and technology), (Nanotechnology science and technology). New York: Nova
Science Publishers, 2012, str. 135-156.
CÖR, Darija, BOTIĆ, Tanja, KNEZ, Željko, BATISTA, Urška, GREGORI, Andrej, POHLEVEN, Franc, BONČINA, Tonica.
Two-stage extraction of antitumor, antioxidant and antiacetylcholinesterase compounds from Ganoderma lucidum
fruiting body. The Journal of supercritical fluids, ISSN 0896-8446, 2014, vol. 91, str. 53-60, doi:
10.1016/j.supflu.2014.04.006.
LEITGEB, Maja, HOJNIK PODREPŠEK, Gordana, KNEZ, Željko. Magnetic nanocarriers for targeted drug delivery. V:
SABBAS, Nora P. (ur.). Magnetic nanoparticles : synthesis, physicochemical properties and role in biomedicine,
(Nanotechnology science and technology). New York: Nova Science Publishers, 2014, str. 201-230.
KNEZ, Željko, MARKOČIČ, Elena, LEITGEB, Maja, PRIMOŽIČ, Mateja, KNEZ HRNČIČ, Maša, ŠKERGET, Mojca.
Industrial applications of supercritical fluids: a review. Energy, ISSN 0360-5442, 2014, str. 1-9, doi:
10.1016/j.energy.2014.07.044.
102
Biokemija, mikrobiologija in molekularna biologija
Predmet:
Course title:
UČNI NAČRT PREDMETA / COURSE SYLLABUS
Biokemija, mikrobiologija in molekularna biologija
Biochemistry, Microbiology and Molecular biology
Študijski program in stopnja
Study programme and level
Kemijska tehnika / 2. stopnja
Chemical Engineering / 2nd level
Študijska smer
Study field
Biokemijska tehnika
Biochemical Engineering
Vrsta predmeta / Course type:
Letnik
Academic year
2.
Semester
Semester
zimski
Autumn
Izbirni / Optional
Univerzitetna koda predmeta / University course code:
Predavanja
Lectures
15
Seminar
Seminar
Nosilec predmeta / Lecturer:
Jeziki /
Languages:
Sem. vaje
Tutorial
Lab. vaje
Labor work
15
Teren. vaje
Field work
Samost. delo
Individ. work
150
ECTS
6
Uroš Potočnik, Maja Leitgeb
Predavanja / Lecture: slovenščina / Slovene
Vaje / Tutorial: slovenščina / Slovene
Pogoji za vključitev v delo oz. za opravljanje
študijskih obveznosti:
Osnovna znanja iz mikrobiologije.
Prerequisites:
Basic knowledge of microbiology.
Vsebina:
Morfologija mikroorganizmov.
Celična struktura. Struktura in funkcija celičnih
membran. Celična stena prokariot. Struktura in
funkcija subcelularnih organel.
Razmnoževanje mikroorganizmov.
Komunikacija med celicami in prenos signalov
Proteini: struktura in vloga v bioloških procesih,
analiza plazemskih proteinov za diagnosticiranje
bolezni, analiza aminokislin za diagnosticiranje
bolezni, povezave med strukturo in funkcijo v
proteinskih družinah, Naddružina
imunoglobulinov, DNA vezavni proteini
Biološke membrane: zgradba in biološka vloga,
aktivni in pasivni transport, liposomi kot prenašalci
zdravil in encimov, bolezni, ki so posledica izgube
fluidnosti celične membrane in okvare
membranskih transportnih sistemov
Metabolizem ogljikovih hidratov: glavne
metabolne poti in njihova kontrola, posebne
metabolne poti, sladkorna bolezen
Content (Syllabus outline):
Morphology of microorganisms.
Cell structure. Structure and function of cell
membranes. Cell wall of prokaryotes. Structure
and functional role of subcellular organelles
Microbial growth.
Cell communication and signal transduction
Proteins: Architecture and Biological Function,
Plasma Proteins in Diagnosis of Disease, Use of
Amino Acid Analysis in Diagnosis of Disease,
Structure Function Relationships in Protein
Families, The Immunoglobulin Superfamily, DNABinding Proteins
Biological Membranes: Structure and biological
function, Active and passive Membrane
Transport, Liposomes as Carriers of Drugs and
Enzymes, Diseases Due to Abnormalities of Cell
Membrane Fluidity and Loss of Membrane
Transport Systems
Carbohydrates Methabolism: Major Metabolic
Pathways and Their Control, Special Pathways,
103
Osnove molekularne genetike: DNA struktura in
lastnosti, replikacija (prokarionti, eukarionti),
rekombinacija DNA, DNA popravljalni, mehanizmi,
mehanizem nastanka DNA mutacij, organizacija,
struktura in funkcija genov, struktura genoma
(rastlinski, živalski in človeški), transkripcija,
translacija, regulacija genske ekspresije
Osnove dedovanja, kromosomska teorija dednosti,
Mendlovo dedovanje, poligensko dedovanje
Rak
Imunski sistem
Uporaba mikroorganizmov v raziskavah in
industriji
Diabetes Mellitus
Basic molecular genetics: DNA structure and
characteristics,
replication
(prokaryotes,
eukaryotes),
recombination,
repair
and
mutations, organization, structure and function of
genes and chromosomes, genome structure
(plant, animal, human) transcription (prokaryotes,
eukaryotes), translation, regulation of gene
expression
Chromosomal basis of heredity, Mendelian
inheritance, polygenic inheritance
Cancer
Immune system
Microorganisms as tools for research and industry
Laboratorijske vaje:
 Karakterizacijske in separacijske metode v
mikrobiologiji
 Izolacija in analiza bakterijske DNA, RNA in
proteinov
Laboratory work:
 Characterization and separation methods in
microbiology
 Isolation of bacterial DNA, RNA and proteins
Temeljni literatura in viri / Textbooks:
 Madigan, T.M., Martinko, J.M., Parker, J.: Brock Biology of Microorganisms, 11th Ed., Prentice Hall, Inc.,
New Jersey, 2006.
 Voet, Donald: Fundamentals of biochemistry: life at the molecular level, 2nd ed., J. Wiley & sons,
Hoboken (New Jersey), 2006.
Dodatna priporočena literatura:
 Nelson D. L., Cox M. M.; Lehninger Principles of Biochemistry, 4th ed, W.H. Freeman and Company,
New York, 2004.
 Strachan T., Read A. P.: Human Molecular genetics, Gerland Publish, Inc., New York, 3rd ed., 2004.
 Lodish H., Baltimore D., Berk A., Zipursky S.L., Matsudaira P., Darnell J.: Molecular Cell Biology, 6th Ed.,
Scientific American Books, Freeman and Co., New York, 2008.
Cilji in kompetence:
Študenti bodo razumeli strukturne značilnosti in
lastnosti glavnih skupin biomolekul ter njihovo
vlogo v metabolizmu in ostalih bioloških procesih.
Objectives and competences:
Students will understand structural characteristics
of major groups of biomolecules and their role in
cell metabolism and other important biological
processes.
Predvideni študijski rezultati:
Znanje in razumevanje:
Študenti bodo razumeli strukturne značilnosti in
lastnosti glavnih skupin biomolekul ter njihovo
vlogo v metabolizmu in ostalih bioloških procesih:
 zakonitosti prenosa genetske informacije med
generacijami
 povezave med genotipom in fenotipom
Intended learning outcomes:
Knowledge and Understanding:
Students will understand structural characteristics
and properties of main groups of biomolecules, and
their role in the methabolism and other biological
processes:
 principles of heredity and transfer of genetic
information between generations
 correlations genotype-phenotype
Prenesljive/ključne spretnosti in drugi atributi:
 pristopi in orodja statistične genetike
Transferable/Key Skills and other attributes:
 approaches and program tools for statistical
genetics
104
Metode poučevanja in učenja:
 predavanja
 seminarske vaje
 laboratorijske vaje
Načini ocenjevanja:
Izpit je opravljen, če so pozitivno
opravljene vse naslednje obveznosti:
 pisni izpit
 ustni izpit
Learning and teaching methods:
 Lectures
 Tutorial
 Laboratory work
Delež (v %) /
Weight (in %)
60
40
Assessment:
Student has to pass successfully the
following obligations:
 written examination
 oral exemination
Reference nosilca / Lecturer’s references:
JOSTINS, Luke, MITROVIČ, Mitja, POTOČNIK, Uroš, et al. Host-microbe interactions have shaped the genetic
architecture of inflammatorybowel disease. Nature, ISSN 0028-0836, 2012, vol. 491, no. 7422, str. 119-124, doi:
10.1038/nature11582. [COBISS.SI-ID 512230968]
REPNIK, Katja, POTOČNIK, Uroš. Haplotype in the IBD5 region is associated with refractory Crohn's disease in
Slovenian patients and modulates expression of the SLC22A5 gene. Journal of gastroenterology, ISSN 0944-1174,
2011, vol. 46, no. 9, str. 1081-1091, doi: 10.1007/s00535-011-0426-6. [COBISS.SI-ID 15110422]
PERIN, Petra, POTOČNIK, Uroš. Polymorphisms in recent GWA identified asthma genes CA10, SGK493, and CTNNA3
are associated with disease severity and treatment response in childhood asthma. Immunogenetics, ISSN 00937711, 2014, vol. 66, issue 3, str. 143-151, doi: 10.1007/s00251-013-0755-0. [COBISS.SI-ID 17472790]
LEITGEB, Maja, ČOLNIK, Maja, PRIMOŽIČ, Mateja, ZALAR, Polona, GUNDE-CIMERMAN, Nina, KNEZ, Željko. Activity
of cellulase and [alpha]-amylase from Hortaea werneckii after cell treatment with supercritical carbon dioxide. The
Journal of supercritical fluids, ISSN 0896-8446. 2013, 78, 143-148, doi: 10.1016/j.supflu.2013.03.029. [COBISS.SIID 16864790]
ČOLNIK, Maja, PRIMOŽIČ, Mateja, KNEZ, Željko, LEITGEB, Maja. Use of supercritical carbon dioxide for proteins and
alcohol dehydrogenase release from yeast Saccharomyces cerevisiae. The Journal of supercritical fluids, ISSN 08968446. 2012, 65, 11-17, doi: 10.1016/j.supflu.2012.02.018. [COBISS.SI-ID 15901462]
KNEZ, Željko, KAVČIČ, Sabina, GUBICZA, László, BÉLAFI-BAKÓ, Katalin, NÉMETH, Gergely, PRIMOŽIČ, Mateja,
LEITGEB, Maja. Lipase-catalyzed esterification of lactic acid in supercritical carbon dioxide. The Journal of
supercritical fluids, ISSN 0896-8446. 2012, 66, 192-197, doi: 10.1016/j.supflu.2011.11. [COBISS.SI-ID 15598102]
ŠULEK, Franja, PÉREZ FERNÁNDEZ, Daniel, KNEZ, Željko, LEITGEB, Maja, SHELDON, Roger A. Immobilization of
horseradish peroxidase as crosslinked enzyme aggregates (CLEAs). Process biochemistry, ISSN 1359-5113, 2011, 46
(3), 765-769, doi: 10.1016/j.procbio.2010.12.001. [COBISS.SI-ID 14712598]
KAVČIČ, Sabina, KNEZ, Željko, LEITGEB, Maja. Antimicrobial activity of n-butyl lactate obtained via enzymatic
esterification of lactic acid with n-butanol in supercritical trifluoromethane. The Journal of supercritical fluids, ISSN
0896-8446. 2014, 85, 143-150, doi: 10.1016/j.supflu.2013.11.003. [COBISS.SI-ID 17392406]
105
Industrijski projekt
Predmet:
Course title:
UČNI NAČRT PREDMETA / COURSE SYLLABUS
Industrijski projekt
Industrial Project
Študijski program in stopnja
Study programme and level
Kemijska tehnika / 2. stopnja
Chemical Engineering / 2nd level
Študijska smer
Study field
Letnik
Academic year
2.
Vrsta predmeta / Course type:
Semester
Semester
letni
Spring
Obvezni / Obligatory
Univerzitetna koda predmeta / University course code:
Predavanja
Lectures
Seminar
Seminar
Nosilec predmeta / Lecturer:
Jeziki /
Languages:
Sem. vaje
Tutorial
Lab. vaje
Labor work
Teren. vaje
Field work
Samost. delo
Individ. work
150
ECTS
5
Koordinator praks / Coordinator of industrial projects
Predavanja / Lecture: Slovenski/Slovene
Vaje / Tutorial: Slovenski/Slovene
Pogoji za vključitev v delo oz. za opravljanje
študijskih obveznosti:
Pogojev ni.
Prerequisites:
Vsebina:
Študent izvaja industrijski projekt s polnim
delovnim časom v (industrijski) organizaciji s
področja kemije, kemijske in biokemijske tehnike
ali drugih procesnih panog. Izjemoma lahko
študent izvaja industrijski projekt tudi na fakulteti
ali inštitutu, če je zaradi narave projekta to
primerneje.
Študentu sta dodeljena mentor v organizaciji in na
Fakulteti za kemijo in kemijsko tehnologijo, ki je
praviloma tudi mentor študentovega magistrskega
dela. V času izvajanja industrijskega projekta se
študent seznani z organiziranostjo, obratovanjem
in poslovanjem organizacije. V okviru projekta
obravnava specifični problem v organizaciji.
Mentor v organizaciji vodi študenta pri izvajanju
aktivnosti, ki pripeljejo do uspešnega zaključka
projekta.
Študent o izvajanju in rezultatih industrijskega
projekta napiše poročilo.
Content (Syllabus outline):
Student works full-time in an (industrial)
organization in the field of chemistry, chemical and
biochemical engineering or other process related
industries. The industrial project could be
exceptionally carried out at the Faculty or Institute if
this is required by the nature of project work.
Two mentors are appointed to student: one in the
organization, and the other one at the Faculty of
Chemistry and Chemical Engineering, who is, as a
rule, mentor of student’s Master Thesis. Student
becomes acquainted with the structure, production
process and management in the organization.
Within the industrial project, student deals with the
specific problem in the organization. Mentor in the
organization leads student’s activities to the
successful finish of the project.
Student prepares a written report about the
execution and results of the industrial project.
None.
106
Temeljni literatura in viri / Textbooks:
 Specifično literaturo bodo študentom posredovali mentorji.
Cilji in kompetence:
Namen industrijskega projekta je, da študent:
 določen čas dela v (industrijski) organizaciji s
področja kemijske in biokemijske tehnike ali
druge procesne panoge
 spozna organiziranost, obratovanje in
poslovanje neakademske organizacije
 uporabi teoretično znanje, pridobljeno med
študijem, za reševanje konkretnega problema v
praksi
 pridobi specifične spretnosti, ki jih ne more
pridobiti na fakulteti
Objectives and competences:
The aim of the industrial project is to:
 work for the specified time period in an industrial
chemical, biochemical or other process related
organization
 become familiar with the structure as well as with
production and management processes in nonacademic organization
 apply knowledge gained during the study for
solving practical problem
 acquire skills different from the ones taught at
the Faculty
Predvideni študijski rezultati:
Znanje in razumevanje:
 poznavanje organiziranosti, obratovanja in
poslovanja neakademskih organizacij
 boljše poznavanje zaposlitvenih možnosti po
zaključku študija
 boljše poznavanje in razumevanje nalog in
odgovornosti v poklicnem okolju
Intended learning outcomes:
Knowledge and Understanding:
 to understand the structure, production and
management process in non-academic
organization
 to increase understanding of employment options
after graduation
 to get a better perception of tasks and
responsibilities within a professional environment
Prenesljive/ključne spretnosti in drugi atributi:
 prilagajanje obnašanja in ravnanja v različnih
poklicnih okoljih
 širši pogled na položaj organizacije v določeni
panogi in globalnem gospodarstvu
(konkurenčnost)
 pridobljene nove spretnosti, ki so potrebne za
uspešno izvajanje in zaključek praktičnega
projekta
Transferable/Key Skills and other attributes:
 to learn a different way of behavior, suitable for
different professional environments
 to obtain a better view of the position of a
company compared to other companies and
global economy (competition)
 to obtain new skills that are necessary to
successfully accomplish practical project
Metode poučevanja in učenja:
 samostojno delo
 konzultacije z mentorjem v organizaciji
 priprava pisnega poročila
Learning and teaching methods:
  independent work
 consultations between student and mentor in the
organization
 preparation of written report
Delež (v %) /
Načini ocenjevanja:
Weight (in %)
Assessment:
Industrijski projekt je zaključen, če so
Student has to pass successfully the
pozitivno opravljene naslednje obveznosti:
following obligations:
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 pisno poročilo industrijskega projekta
 written report of industrial project
Reference nosilca / Lecturer's references:
107
Magistrsko delo
Predmet:
Course title:
UČNI NAČRT PREDMETA / COURSE SYLLABUS
Magistrsko delo
Master Thesis
Študijski program in stopnja
Study programme and level
Kemijska tehnika / 2. stopnja
Chemical Engineering / 2nd level
Študijska smer
Study field
Letnik
Academic year
2.
Vrsta predmeta / Course type:
Semester
Semester
letni
Spring
Obvezni / Obligatory
Univerzitetna koda predmeta / University course code:
Predavanja
Lectures
Seminar
Seminar
Sem. vaje
Lab. vaje
Drugo*
Samost. delo
Tutorial
Labor work
Other
Individ. work
20
20
730
*Individualne kontaktne ure s profesorjem/Individual contact hours with lecturer
Nosilec predmeta / Lecturer:
Jeziki /
Languages:
ECTS
25
Vsi habilitirani visokošolski učitelji / All lecturers holding valid
habilitation
Predavanja / Lecture:
Vaje / Tutorial: slovenski / Slovene
Pogoji za vključitev v delo oz. za opravljanje
študijskih obveznosti:
Prerequisites:
Vsebina:
Priprava magistrskega dela poteka kot samostojno
delo študenta na raziskovalnem projektu s
področja kemijske ali biokemijske tehnike.
Magistrsko delo je lahko tudi skupni raziskovalni
projekt več študentov. Teme projektov za
magistrska dela razpišejo mentorji v okviru
raziskovalnih laboratorijev Fakultete za kemijo in
kemijsko tehnologijo ali jih predlagajo študentje.
Študent pridobi soglasje predvidenega mentorja, ki
ga usmerja in svetuje pri izvedbi magistrskega dela.
Formalni postopek priprave in zagovora
magistrskega dela poteka v skladu s Pravilnikom o
postopku priprave in zagovora magistrskega dela
na študijskem programu 2. stopnje, Univerze v
Mariboru.
Predvidene aktivnosti študenta pri pripravi in
zagovoru magistrskega dela so naslednje:
 formulacija problema
Content (Syllabus outline):
The student has to work independently on a
research project concerning chemical or biochemical
engineering problem. Master thesis can be a
common research project of several students. The
research topics are issued by the mentors in the
research laboratories of the Faculty of Chemistry
and Chemical Engineering or could be initiated by
students. Consent of mentor is required. Mentor
guides the student through the research work of
Master Thesis.
The formal procedure for Master Thesis preparation
and defence is regulated by the “Pravilnik o
postopku priprave in zagovora magistrskega dela na
študijskem programu 2. stopnje” of the University of
Maribor.
The preparation and defence of Master Thesis
usually include the following activities of student:
 problem formulation
108
 pregled in analiza dosedanjih raziskav in







relevantne literature
postavitev raziskovalnih hipotez
definiranje metod dela
časovni načrt izvedbe projekta
praktično delo v enem od raziskovalnih
laboratorijev fakultete
interpretacija in kritična presoja rezultatov
priprava pisnega izdelka
ustna predstavitev.
 state-of-the-art in the proposed field of research







and survey of the relevant literature
definition of research hypotheses
definition of research methods
time plan of project
practical work in one of the Faculty research
laboratories
interpretation and evaluation of the results
written presentation of the work
oral presentation of the work.
Temeljni literatura in viri / Textbooks:
 Kravanja Zdravko, Navodila za kvalitetno izvajanje magistrskega dela. Univerza v Mariboru, Fakulteta
za kemijo in kemijsko tehnologijo, Maribor, 2014.
http://www.fkkt.um.si/sites/default/files/Navodila%20za%20kvalitetno%20magistrsko%20delo_0.pdf
 Novak Pintarič Zorka, Kravanja Zdravko, Predloga z navodili za pisanje magistrskega dela. Univerza v
Mariboru, Fakulteta za kemijo in kemijsko tehnologijo, Maribor, 2015.
http://www.fkkt.um.si/sites/default/files/Predloga_MAG_KT-2015.docx
 Univerza v Mariboru, Pravilnik o postopku priprave in zagovora magistrskega dela na študijskem
programu 2. stopnje. Obvestila UM št. XXX-5-2012, Univerza v Mariboru, 2012.
http://www.um.si/univerza/dokumentni-center/akti/Strani/podrobnosti.aspx?iddok=150.
Dodatna priporočena literatura:
 Peter Glavič: Navodila za izdelavo diplomskega dela. Univerza v Mariboru, Fakulteta za kemijo in
kemijsko tehnologijo, Maribor, 2008.
 Specifično literaturo bodo študentom posredovali mentorji.
Cilji in kompetence:
Cilj je, da študent doseže:
 sposobnost branja in razumevanja mednarodne
literature o določenem problemu
 sposobnost samostojnega raziskovalnorazvojnega dela z namenom reševanja
določenega problema
 sposobnost dela v interdisciplinarni skupini
strokovnjakov
 sposobnost predstavitve rezultatov dela
strokovni javnosti v obliki pisnega poročila,
predavanja, diskusije.
Objectives and competences:
The student would be able to:
 read and understand international literature of a
specific topic
 work independently in a research and
development environment in order to solve
specific problem
 work in an interdisciplinary team of experts
 present the results to a professional audience by
means of a a written report, oral presentation
and discussion.
Predvideni študijski rezultati:
Znanje in razumevanje:
 poglobljeno obvladanje znanj in izrazoslovja s
strokovnega področja magistrskega dela
 poznavanje sistematike, metod in pristopov
raziskovalno-razvojnega dela
 sposobnost identifikacije, formulacije in
reševanja problemov s področja kemijske in
biokemijske tehnike
Intended learning outcomes:
Knowledge and Understanding:
 mastery of knowledge and terminology in the
specific professional field of Master Thesis
 knowledge of systematics, methods and
approaches of research and development work,
 ability of identification, formulation and solution
of problems in the field of Chemical and
Biochemical Engineering
Prenesljive/ključne spretnosti in drugi atributi:
 sposobnost samostojnega raziskovalnega dela,
reševanja strokovnih problemov, kritičnega
razmišljanja in razumevanja strokovne literature
 sposobnost učinkovite komunikacije o strokovni
problematiki
Transferable/Key Skills and other attributes:
 ability to independently accomplish the research
work, solve the professional problems,
understand the literature and to think critically
 ability to efficiently communicate about
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 sposobnost učinkovite predstavitve in
problematics,
 ability to efficiently present and interpret the
results of work.
interpretacije rezultatov dela.
Metode poučevanja in učenja:
 konzultacije in diskusije študenta z mentorjem o
vsebinskem poteku dela
 priprava pisnega izdelka in ustne predstavitve
Learning and teaching methods:
  consultations and discussions between student
and mentor about the content and progress of
the work
 preparation of written report and oral
presentation
Delež (v %) /
Načini ocenjevanja:
Weight (in %)
Assessment:
Magistrsko delo je zaključeno, če so
Student has to pass successfully the
pozitivno opravljene naslednje obveznosti:
following obligations:
 magistrsko delo
 ustni zagovor magistrskega dela
50
50
Reference nosilca / Lecturer's references:
110
 master thesis work
 master thesis oral presentation