Obrazec za opis predmeta SLO/ENG
Transcription
Obrazec za opis predmeta SLO/ENG
Termodifuzijska tehnika Predmet: Course title: UČNI NAČRT PREDMETA / COURSE SYLLABUS Termodifuzijska tehnika Stagewise Processes Študijski program in stopnja Study programme and level Študijska smer Study field Letnik Academic year Semester Semester 1. zimski Autumn Kemijska tehnika / 2. stopnja Chemical Engineering / 2nd level Vrsta predmeta / Course type: Obvezni / Obligatory Univerzitetna koda predmeta / University course code: Predavanja Lectures Seminar Seminar Sem. vaje Tutorial 60 Nosilec predmeta / Lecturer: Jeziki / Languages: Lab. vaje Laboratory work 50 Teren. vaje Field work Samost. delo Individ. work ECTS 160 9 Željko Knez Predavanja / Lectures: slovenski / Slovene Vaje / Tutorial: slovenski / Slovene Pogoji za vključitev v delo oz. za opravljanje študijskih obveznosti: Osvojeni pojmi in osnovna znanja s področij fizike, fizikalne kemije, termodinamike in prenosnih pojavov. Prerequisits: Vsebina: Uparjanje. Procesni parametri. Tipi uparjalnikov. Postopki uparjanja. Dimenzioniranje uparjalnikov. Kristalizacija. Osnove kristalizacije. Ravnotežje pri kristalizaciji. Hitrost tvorbe kristalnih jeder in rasti kristalov. Dimenzioniranje kristalizatorjev. Destilacija. Ravnotežje pri destilaciji. Vrste destilacij. Rektifikacija. Vrste rektifikacij. Rektifikacijske naprave. Dimenzioniranje kolon. Ekstrakcija trdno-tekoče. Hitrost ekstrakcije. Prenos snovi pri ekstrakciji trdnih snovi. Vrste ekstraktorjev. Dimenzioniranje ekstrakcijske baterije. Ekstrakcija tekočih zmesi. Osnove. Postopki ekstrakcije tekoče-tekoče. Aparati za ekstrakcijo tekočih zmesi. Hitrost ekstrakcije. Content (Syllabus outline): Evaporation. Process parameters. Types of evaporators. Processes of evaporation. Design of evaporators. Crystallization. Fundamentals of crystallization. Equilibrium in crystallization. The rate of crystal core formation and crystal growth. Design of crystallizators. Distillation. Equilibrium in a distillation. Distillation types. Rectification. Rectification types. Rectification apparatus. Design of column. Solid-liquid extraction. Extraction rate. Mass transfer in solid extraction. Extractor types. Design of extraction battery. Extraction of liquid mixtures. Fundamentals. Processes of liquid-liquid extractions. Extraction apparatus for liquid mixtures. Extraction rate. Basic knowledge of physics, physical chemistry, thermodynamics and transport phenomena. 1 Dimenzioniranje protitočne ekstrakcijske baterije. Tehnologije s fluidi nad kritično točko Ekstrakcijski procesi s superkritičnimi fluidi. Biokemijske reakcije v superkritičnih fluidih. Uporaba superkritičnih fluidov za mikronizacijo. Sušenje. Namen in potek sušenja. Metode sušenja. Osnove psihrometrije. Mehanizem sušenja s hlapljenjem. Vrste sušilnikov. Dimenzioniranje sušilnikov. Design of counter current extraction battery. Technologies with fluids above critical point. Extraction processes with supercritical fluids Biochemical reactions in supercritical fluids. Application of supercritical fluids for micronization. Drying. Purpose and procedure of drying. Drying methods. Fundamentals of psihrometry. The mechanism of drying with evaporation. Dryer types. Laboratorijske vaje: V okviru laboratorijskih vaj se izvaja tankoslojno uparjanje, diferencialna destilacija, rektifikacija, ekstrakcija trdno-tekoče, in sušenje. Laboratory work: Laboratory work includes thin-layer evaporation, differential distillation, rectification, solid-liquid extraction, and drying. Temeljni literatura in viri / Readings: Ž. Knez, M. Škerget, Termodifuzijski separacijski procesi, FKKT, Maribor, 2009. Dodatna priporočena literatura: K. Sattler, H. J. Feindt, Thermal Separation Processes: Principles and Design, VCH, Weinheim, 2007. Paul T. Anastas, Carlos A. M. Afonso, João Pedro G. Crespo, Green Separation Processes: Fundamentals and Applications, VCH, Weinheim, 2005. V. Anikeev, M. Fan, Supercritical Fluid Technology for Energy and Environmental Applications, Elsevier, 2014. Cilji in kompetence: Predmet sodi med osnovne kemijsko inženirske predmete. Kot sinteza kemijske in inženirske termodinamike, transportnih fenomenov ter masnih in toplotnih bilanc zagotovi osnovno znanje, ki ga inženir-tehnolog potrebuje pri vodenju in načrtovanju separacijskih procesov ter naprav. Predmet razvija študentu sposobnost analize in sinteze kompleksnih kemijsko tehnoloških sistemov. Objectives and competences: The subject is one of the fundamental subjects in Chemical engineering. As synthesis of chemical and engineering thermodynamics, transport phenomena, as well as mass and heat balance, it assures the basic knowledge for an engineertechnologist, which is needed in control and design of separation processes and apparatus. The subject develops the student ability of analysis and synthesis of complex chemical technological systems. Predvideni študijski rezultati: Znanje in razumevanje: Zmožnost načrtovanja destilacijskega, uprajalnega ali ekstrakcijskega sistema. Uporaba ustreznih procesnih parametrov v povezavi z načrtovanim sistemom. Intended learning outcomes: Knowledge and understanding: Design of distillation, evaporation or extraction system. Application of proper process parameters for a defined process analysis. Prenesljive/ključne spretnosti in drugi atributi: Vsebina predmeta je povezana z ostalimi predmeti na smeri Kemijska tehnika in podaja znanja, potrebna za razumevanje vsebin, ki so zajeta npr. pri predmetu Bioseparacijska tehnika in biokataliza. Transferable/Key Skills and other attributes: The subject is connected to other subjects on the direction Chemical engineering and gives the knowledge which is necessary for understanding other subjects such as Bioseparation engineering and biocatalysis. Metode poučevanja in učenja: - predavanja - laboratorijske vaje Learning and teaching methods: lectures laboratory work 2 Načini ocenjevanja: Način (pisni izpit, ustno izpraševanje, naloge, projekt) Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: pisni izpit ustni izpit laboratorijske vaje Delež (v %) / Weight (in %) 60 30 10 Assessment: Type (examination, oral, coursework, project): Student has to pass successfully the following obligations: written examination oral examination laboratory work Reference nosilca / Lecturer’s references: KNEZ, Željko, ŠKERGET, Mojca, KNEZ HRNČIČ, Maša. Principles of supercritical fluid extraction and applications in the food, beverage and nutraceutical industries. V: RIZVI, Syed S. H. (ur.). Separation, extraction and concentration processes in the food, beverage and nutraceutical industries. Oxford [etc.]: Woodhead Publishing Limited, 2010, str. [3]-38. REIBE, Christian, KNEZ, Željko, WEIDNER, Eckhard. A new high-pressure micronisation process for the gentle processing of high molecular mass gelatine. Food and bioproducts processing, ISSN 0960-3085, 2012, vol. 90, no. 2, str. 79-86, doi: 10.1016/j.fbp.2011.02.001. KNEZ, Željko, MARKOČIČ, Elena, LEITGEB, Maja, PRIMOŽIČ, Mateja, KNEZ HRNČIČ, Maša, ŠKERGET, Mojca. Industrial applications of supercritical fluids : a review. Energy, ISSN 0360-5442, 2014, str. 1-9, doi: 10.1016/j.energy.2014.07.044. KNEZ, Željko, MARKOČIČ, Elena, KNEZ HRNČIČ, Maša, RAVBER, Matej, ŠKERGET, Mojca. High pressure water reforming of biomass for energy and chemicals : a short review. The Journal of supercritical fluids, ISSN 0896-8446, 2014, vol. , str. 1-8, doi: 10.1016/j.supflu.2014.06.008. RAVBER, Matej, KNEZ, Željko, ŠKERGET, Mojca. Simultaneous extraction of oil- and water-soluble phase from sunflower seeds with subcritical water. Food chemistry, ISSN 0308-8146, 2015, vol. 166, str. 316-323, doi: 10.1016/j.foodchem.2014.06.025. 3 Načrtovanje procesov Predmet: Course title: UČNI NAČRT PREDMETA / COURSE SYLLABUS Načrtovanje procesov Process Design Študijski program in stopnja Study programme and level Kemijska tehnika / 2. stopnja Chemical Engineering / 2nd level Študijska smer Study field Letnik Academic year 1. Vrsta predmeta / Course type: Semester Semester zimski Autumn Obvezni / Obligatory Univerzitetna koda predmeta / University course code: Predavanja Lectures 45 Seminar Seminar Nosilec predmeta / Lecturer: Jeziki: Languages: Sem. vaje Tutorial 30 Lab. vaje Labor work Teren. vaje Field work Samost. delo Individ. work 105 ECTS 6 Zorka Novak Pintarič Predavanja / Lecture: slovenski / Slovene Vaje / Tutorial: slovenski / Slovene Pogoji za vključitev v delo oz. za opravljanje študijskih obveznosti: Potrebno je znanje iz termodinamike, prenosa toplote in snovi ter osnovno znanje iz separacijske in reakcijske tehnike. Prerequisites: Vsebina: Strategije načrtovanja in integracije kemijskih procesov (hierarhična, termodinamska, algoritemska). Modeli za oceno termofizikalnih lastnosti v simulatorjih. Načrtovanje in simulacija procesnih podsistemov: - reakcijske poti, reaktorji in reaktorska omrežja, - separatorji in separacijska omrežja. - omrežje reaktor-separator-obtok. Procesna integracija: - integrirana omrežja toplotnih prenosnikov, - toplotna integracija reaktorjev, separatorjev in separacijskih omrežij, - toplotni stroji in toplotne črpalke, - vpliv toplotne integracije na obtok in celotno presnovo reaktantov, - vodna integracija. Načrtovanje šaržnih procesov. Načrtovanje integriranih, trajnostnih procesov. Content (Syllabus outline): Strategies for chemical process design and integration (hierarchic, thermodynamic, algorithmic). Models for thermophysical property data in process simulators. Design and simulation of process subsystems: - reaction paths, reactors and reactor networks, - separators and separation sequencing, - reactor-separator-recycle networks. Process integration: - heat exchanger networks, - heat integration of reactors, separators and separation networks, - heat engines and heat pumps, - interactions of heat integration, purge-to-recycle ratio and overall conversion of reactants, - water integration. Design of batch processes. Design of integrated sustainable processes. Knowledge about thermodynamics, heat and mass transfer and basic knowledge about separation and reaction engineering is required. 4 Sprotno reševanje domačih nalog. Ongoing homework assignments. Računalniške vaje: Simulacije posameznih procesnih enot in procesnih podsistemov. Projektna naloga, procesna shema in simulacija procesa. Computer Exercises: Simulation of process equipment and process subsystems. Process design project formulation, process flow sheet simulation. Temeljni literatura in viri / Textbooks: Z. Novak Pintarič, Načrtovanje in integracija procesov, zbrano gradivo. Univerza v Mariboru, Fakulteta za kemijo in kemijsko tehnologijo, Maribor, 2014. Z. Novak Pintarič, Simulacija kemijskih procesov, zbrano gradivo. Univerza v Mariboru, Fakulteta za kemijo in kemijsko tehnologijo, Maribor, 2014. Dodatna priporočena literatura: R. Smith, Chemical Process Design and Integration, J. Wiley, 2005. W. D. Seider, J. D. Seader, D. R. Lewin: Product and process design principles: synthesis, analysis, and evaluation. Second Edition, Wiley, New York, 2004. J. J. Klemeš (Ed.), Handbook of Process Integration (PI), Woodhead Publishing, Cambridge, 2013. Cilji in kompetence: Študent spozna konceptualno načrtovanje kemijskih procesov, osvoji osnove procesno sistemskega pristopa in integracije procesov s poudarkom na hierarhičnih in termodinamskih metodah. Objectives and competences: To acquaint students with conceptual design of chemical processes. To acquire process system engineering approach to process design and integration, based on hierarchic and thermodynamic methods. Predvideni študijski rezultati: Znanje in razumevanje: Študent obvlada konceptualno načrtovanje kemijskih procesov. Razume povezanost podsistemov reakcija-separacija-obtok-toplotna integracija. Razume vpliv toplotne integracije in razmerja obtok/odtok na celotno presnovo reaktantov. Spozna simulacijo procesov in termodinamske metode za integracijo procesov. Prenesljive/ključne spretnosti in drugi atributi: Računalniško načrtovanje reaktorjev, separatorjev, toplotnih strojev in črpalk, celotnih procesnih shem. Razvijanje sposobnosti za skupinsko in projektno delo. Intended learning outcomes: Knowledge and Understanding: Students master the conceptual design of chemical processes. They understand the interactions of process subsystems, e.g. reaction, separation, recycle and heat integration. Students understand the tradeoffs between heat integration, purge-torecycle ratio, recycle ratio, and overall conversion of reactants. They are acquinted with simulation of process flow sheets and process integration by thermodynamic methods. Transferable/key skills and other attributes: Computer aided design and retrofit of reactors, separators, heat engines, heat pumps, and process flow sheets. Abilities to work in team. Experience in executing large projects. Metode poučevanja in učenja: Aktivno poučevanje in učenje. Individualne računalniške vaje. Uporaba tujih jezikov in literature. Skupinske računalniške vaje simuliranja, integriranja, načrtovanja. Pisanje in zagovor poročil iz posamičnih vaj in skupinskega projektnega poročila. Learning and teaching methods: Active teaching and learning. Individual work using computers. Usage of foreign languages and literature. Team-work in process design, simulation and integration. Writing and defence of individual work as well as the team design report. 5 Načini ocenjevanja: Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: pisni računski izpit ali dva računska testa izpit teorije ali dva testa teorije projektno poročilo domače naloge Delež (v %) / Weight (in %) 60 20 15 5 Računski test in test teorije se izvajata hkrati. Vse domače naloge morajo biti rešene. Assessment: Student has to pass successfully the following obligations: written exam (calculus) or two written tests (calculus) Theory exam or two theory tests project report homeworks Calculus test and theory test are performed simultaneously. All homework assignments must be completed. Reference nosilca / Lecturer’s references: NOVAK-PINTARIČ, Zorka, KRAVANJA, Zdravko. Suitable process modelling for proper multi-objective optimization of process flow sheets. V: KLEMEŠ, Jiri (ur.), VARBANOV, Petar (ur.), LIEW, Peng Yen (ur.). 24th European Symposium on Computer Aided Process Engineering : [ESCAPE-24, 15 to 18 June 2014, Budapest, Hungary], (Computer aided chemical engineering, ISSN 1570-7946, 33). Amsterdam ... [et al.]: Elsevier, cop. 2014, str. 13881392. [COBISS.SI-ID 18172438] NOVAK-PINTARIČ, Zorka, KASAŠ, Mihael, KRAVANJA, Zdravko. Sensitivity analyses for scenario reduction in flexible flow sheet design with a large number of uncertain parameters. AIChE journal, ISSN 0001-1541. [Print ed.], Avg. 2013, vol. 59, iss. 8, str. 2862-2871, doi: 10.1002/aic.14061. [COBISS.SI-ID 16795926] TOKOS, Hella, NOVAK-PINTARIČ, Zorka, GLAVIČ, Peter. Energy saving opportunities in heat integrated beverage plant retrofit. Applied thermal engineering, ISSN 1359-4311. [Print ed.], Jan. 2010, vol. 30, no. 1, str. 36-44, doi: 10.1016/j.applthermaleng.2009.03.008. [COBISS.SI-ID 13122838] TOKOS, Hella, NOVAK-PINTARIČ, Zorka. Synthesis of batch water network for a brewery plant. Journal of cleaner production, ISSN 0959-6526. [Print ed.], Nov. 2009, vol. 17, iss. 16, str. 1465-1479, doi: 10.1016/j.jclepro.2009.06.009. [COBISS.SI-ID 13317910] NOVAK-PINTARIČ, Zorka. Načrtovanje in integracija procesov : zbrano gradivo za predmet Načrtovanje procesov na bolonjskem magistrskem programu Kemijska tehnika. Maribor: Fakulteta za kemijo in kemijsko tehnologijo, 2014. [145] f., ilustr. https://estudij.um.si/mod/resource/view.php?id=21344, http://dkum.unimb.si/IzpisGradiva.php?id=44461. [COBISS.SI-ID 17583638] NOVAK-PINTARIČ, Zorka. Simulacija kemijskih procesov : zbrano gradivo za vaje pri predmetu Načrtovanje procesov na bolonjskem magistrskem programu Kemijska tehnika. Maribor: Fakulteta za kemijo in kemijsko tehnologijo, 2014. [37] f., ilustr. https://estudij.um.si/mod/resource/view.php?id=21375, http://dkum.unimb.si/IzpisGradiva.php?id=44466. [COBISS.SI-ID 17583894] 6 Kemijska reakcijska tehnika II Predmet: Course title: UČNI NAČRT PREDMETA / COURSE SYLLABUS Kemijska reakcijska tehnika II Chemical Reaction Engineering II Študijski program in stopnja Study programme and level Kemijska tehnika / 2. stopnja Chemical Engineering / 2nd level Študijska smer Study field Letnik Academic year 1. Vrsta predmeta / Course type: Semester Semester zimski Autumn Obvezni / Obligatory Univerzitetna koda predmeta / University course code: Predavanja Lectures 45 Seminar Seminar Nosilec predmeta / Lecturer: Jeziki / Languages: Sem. vaje Tutorial Lab. vaje Labor work 30 Teren. vaje Field work Samost. delo Individ. work 105 ECTS 6 Andreja Goršek Predavanja / Lecture: slovenski / Slovene Vaje / Tutorial: slovenski / Slovene Pogoji za vključitev v delo oz. za opravljanje študijskih obveznosti: Potrebno je znanje iz materialov, termodinamike, prenosa toplote in snovi ter osnovno znanje iz separacijske in kemijske reakcijske tehnike. Prerequisites: Vsebina: Predavanja: Heterogeni reakcijski sistemi. Bifluidne in fluosolidne reakcije. Katalizirane reakcije. Temperaturni učinki pri homogenih reakcijah in v stopenjskih reaktorjih z nasuto plastjo. Upor v porah katalizatorja in toplotni učinki. Reaktor s fluidizirano plastjo. Dezaktivirna kataliza. Biokemijski reakcijski sistemi. Načrtovanje reaktorjev (osnove, simulacija procesnih operacij, modeliranje reaktorjev). Izbira materialov (termodinamika in kinetika plinske in elektrolitske korozije, protikorozijska zaščita, pojavne oblike korozije). Content (Syllabus outline): Lectures: Heterogeneous reaction systems. Fluid-fluid and fluid-particle reactions. Solid catalyzed reactions. Temperature effects in homogeneous and packedbed reactors. Catalyst pore resistance, heat effects. Fluidised bed reactor. Deactivating catalysis. Biochemical reaction systems. Reactor design (simulation of process operations, reactor modelling). Material selection (thermodynamics and kinetics of gaseous/electrolytic corrosion, corrosion prevention, and forms of corrosion). Knowledge about materials engineering, thermodynamics, heat and mass transfer and basic knowledge about separation and reaction engineering is required. 7 Računalniške vaje: Modeliranje reaktorjev (mešalni, kaskadni, cevni), kinetika radikalov, heterogena kataliza, kopolimerizacija, porazdelitve bivalnih časov, dinamično modeliranje). Computer Exercises: Reactor modelling (mixed flow, in series, plug flow), kinetics of radicals, heterogeneous catalysis, copolymerization, residence time distribution, dynamic modelling. Laboratorijske vaje: Korozijska odpornost gradiv Katalitski reaktor Laboratory Exercises: Corosion resistance of materials Catalytic reactor Temeljni literatura in viri / Textbooks: P. Glavič, Kemijska reakcijska tehnika, zbirka nalog z navodili in rešitvami, UM FKKT, Maribor, 2007. O. Levenspiel, Chemical Reaction Engineering, 3rd Ed., John Wiley and Sons, New York, 1999. Dodatna priporočena literatura: P. Glavič, Gradiva, UM, FKKT, Maribor, 2006. H. Scott Fogler, Elements of Chemical Reaction Engineering, Prentice-Hall, London, 2005. Cilji in kompetence: Študent se seznani s heterogenimi reakcijskimi sistemi. Dodatno spozna numerično modeliranje in načrtovanje kataliziranih in nekataliziranih reakcijskih sistemov, zahtevnejše vrste reaktorjev in toplotne učinke v njih. Izbira in uporaba gradiv v konstruiranju. Propadanje gradiv in obvladovanje hitrosti korozije. Sinteza znanj iz kemije, termodinamike, osnovnih pojavov in operacij, varnosti in okolja, ekonomike. Objectives and competences: Student is introduced to heterogeneous reaction systems together with modelling of catalytic and non-catalytic reaction systems, more complex reactors and their heat effects. Selection and use of construction materials. Corrosion and corrosion prevention in materials. Synthesis of knowledge, acquired in: chemistry, basic phenomena, thermodynamics, unit operations, safety, environmental protection, economics. Predvideni študijski rezultati: Znanje in razumevanje: Razširitev znanja na kompleksne reakcijske sisteme (več vzporednih, zaporednih, ravnotežnih, kataliziranih reakcij), za katere so značilni komplicirani izrazi za proizvodnost in posebni načini kontaktiranja. Intended learning outcomes: Knowledge and Understanding: Knowledge extension to complex reaction systems (more parallel, series, equilibrium, and catalyzed reactions) with more complicated rate expressions and contacting patterns. Prenesljive/ključne spretnosti in drugi atributi: Razumevanje heterogenih reakcij, pravilna izbira reaktorjev in modeliranje osnovnih ter zahtevnejših tipov reaktorjev (prav tako osnovnih operacij). Transferable/key skills and other attributes: Understanding of heterogeneous reactions, choice of right reactor and modelling of simple and more complex reactors (basic unit operations). Metode poučevanja in učenja: Aktivno poučevanje in učenje. Individualne računalniške vaje. Uporaba tujih jezikov in literature. Računalniške vaje modeliranja. Learning and teaching methods: Active teaching and learning. Individual work using computers. Usage of foreign languages and literature. Computer exercises on modelling. Laboratorijske vaje. Pisanje in zagovor poročil iz posamičnih vaj. Laboratory exercises. Writing and defence of individual work. 8 Načini ocenjevanja: Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: - računalniške vaje - laboratorijske vaje - pisni izpit - ustni izpit Delež (v %) / Weight (in %) 20 10 40 30 Assessment: Student has to pass successfully the following obligations: - computer exercises - laboratory - writen exam (problem solving) - oral exam Reference nosilca / Lecturer’s references: KRIŽAN, Janja, PETRINIĆ, Irena, GORŠEK, Andreja, SIMONIČ, Marjana. Ultrafiltration of oil-in-water emulsion by using ceramic membrane : Taguchi experimental design approach. Central European Journal of Chemistry, ISSN 1895-1066, Feb. 2014, vol. 12, iss. 2, str. 242-249, ilustr., doi: 10.2478/s11532-013-0373-6. [COBISS.SI-ID 17373718]. PEČAR, Darja, GORŠEK, Andreja. Oxidation of menthol : reaction-rate determination based on thermodynamic profiles. Chemical engineering communications, ISSN 0098-6445, 2014, vol. 201, iss. 11, str. 1548-1554. http://www.tandfonline.com/doi/full/10.1080/00986445.2013.819353#.U6E-jU-KDq4. [COBISS.SI-ID 17918998]. ZAJŠEK, Katja, GORŠEK, Andreja, KOLAR, Mitja. Cultivating conditions effects on kefiran production by the mixed culture of lactic acid bacteria imbedded within kefir grains. Food chemistry, ISSN 0308-8146. [Print ed.], Jan. 2013, vol. 139, iss. 1-4, str. 970-977, doi: 10.1016/j.foodchem.2012.11.142. [COBISS.SI-ID 16645142]. GORŠEK, Andreja, TRAMŠEK, Marko. Production of unique naturally immobilized starter : a fractional factorial design approach towards the bioprocess parameters evaluation. V: MATOVIC, Darko (ur.). Biomass - detection, production and usage. Rijeka: InTech, cop. 2011, str. 185-200. http://www.intechopen. com/source/pdfs/19074/InTechProduction_of_unique_naturally_immobilized_starter_a_fractional_factorial_design_approach_towards_the_biop roces s_parameters_evaluation.pdf. [COBISS.SI-ID 15454998]. LEŠER, Tadej, GORŠEK, Andreja. Study of enamel frit melting kinetics. Glass technology, ISSN 0017-1050, Oct. 2013, vol. 54, no. 5, str. 199-203. [COBISS.SI-ID 17385238]. 9 Dinamika in optimiranje procesov Predmet: Course title: UČNI NAČRT PREDMETA / COURSE SYLLABUS Dinamika in optimiranje procesov Process Dynamics and Optimization Študijski program in stopnja Study programme and level Kemijska tehnika / 2. stopnja Chemical Engineering / 2nd level Študijska smer Study field Letnik Academic year 1. Vrsta predmeta / Course type: Semester Semester zimski autumn Obvezni / Obligatory Univerzitetna koda predmeta / University course code: Predavanja Lectures 60 Seminar Seminar Sem. vaje Tutorial Nosilec predmeta / Lecturer: Jeziki / Languages: Lab. vaje Labor work 45 Teren. vaje Field work Samost. delo Individ. work 165 ECTS 9 Zdravko Kravanja Predavanja / Lecture: slovenski / Slovene Vaje / Tutorial: slovenski / Slovene Pogoji za vključitev v delo oz. za opravljanje študijskih obveznosti: Osnove dinamike procesov, linearnega (LP) in nelinearnega programiranja (NLP). Prerequisites: Vsebina: Matematično modeliranje in reševanje: dinamično modeliranje nekaterih osnovnih procesnih operacij, numerična integracija in reševanje diferencialnoalgebrskih sistemov enačb, dinamična simulacija. Content (Syllabus outline): Mathematical modeling and solution: dynamic modeling of some basic process unit operations, numerical integration and solution of differentialalgebraic systems of equations, dynamic simulation. Dinamika procesov: Uvod in načrtovanje sistemov z eno spremenljivko: povratnozančna regulacija in frekvenčna analiza, sistemi z velikim mrtvim časom in inverznim odzivom, večzančne strukture, vnaprejšnja in razmerna regulacija, adaptivna in inferenčna regulacija. Načrtovanje sistemov z več spremenljivkami: alternativne regulcijske konfiguracije, medzančne interakcije in ukrepi, osnove načrtovanja regulacijskih sistemov za celotne obrate. Osnove načrtovanja računalniških regulacijskih sistemov in optimiranja v realnem času. Optimiranje in integracija procesov: Basic knowledge of process dynamics, linear (LP) and nonlinear programming (NLP). Process Dynamics: Introduction and design of single variable control systems (SISO): feedback control and analysis of frequency response, systems with large dead time or inverse response, multiple loop configurations, feedforward control and ratio control, adaptive and inferential control. Multivariable control systems (MIMO): alternative control configurations, interaction of control loops, relative-gain array and decoupling of the loops, basic aspects in designing a control system for overall plant. Basic aspects in designing computer control systems and on-line optimization. 10 Uvod, namenska funkcija in optimizacijski kriteriji v procesnih industrijah. Diskretno in zvezno optimiranje: mešanoceloštevilsko linearno programiranje (MILP) in algoritem vejanja in omejevanja, mešanoceloštevilsko nelinearno programiranje (MINLP) in algoritem zunanje poenostavitve. Optimalno načrtovanje/sinteza toplotno integriranih omrežij toplotnih prenosnikov s sekvenčnim in simultanim pristopom. Optimiranje procesnih shem: SQP – zaporedno kvadratično programiranje, optimiranje s procesnimi simulatorji, optimiranje z enačbnimi sistemi. Načrtovanje in optimiranje saržnih procesov. Računalniške vaje: dinamične simulacije in optimiranje. Process optimization and integration: Introduction, objective function and optimization criteria in process industries. Discrete and continuous optimization: mixedinteger linear programming (MILP) and branchand-bound algorithm, mixed-integer nonlinear programming (MINLP) and outer-approximation algorithm. Optimal design/synthesis of heat integrated heat exchanger networks with sequential and simultaneous approach. Process flowsheet optimization: SQP – successive quadratic programming, optimization with process simulators, and optimization with equation oriented systems. Design and optimization of batch processes. Computer room: dynamic simulation and optimization. Temeljni literatura in viri / Textbooks: Zdravko Kravanja: Dinamika procesov, Zapiski predavanj. Zbrano gradivo. Univerza v Mariboru, Fakulteta za kemijo in kemijsko tehnologijo, Maribor, 2009. Zdravko Kravanja in Zorka Novak Pintarič: Optimiranje procesov, Zapiski predavanj. Zbrano gradivo. Univerza v Mariboru, Fakulteta za kemijo in kemijsko tehnologijo, Maribor, 2006. Dodatna priporočena literatura: Seborg, D. E., T. F. Edgar in D. A. Mellichamp, Process Dynamics and Control (2nd ed.), John Wiley & Sons, New York, 2004. Ravidran A., K. M. Ragsdell in G. V. Reklaitis, Engineering Optimization, Methods and Application (2nd ed.), John Wiley and Sons, New York, 2006. Biegler L. T., I. E.Grossmann and A. W.Westerberg, Systematic Methods of Chemical Process Design, Prentice Hall, New Jersey, 1999. Stephanopoulos G., Chemical Process Control: An Introduction to Theory and Practice, Englewood Cliffs, New Jersey, 1984. Cilji in kompetence: Podati koncept dinamičnega modeliranja in regulacije (bio)kemijskih procesnih enot in obratov in spoznati diskretno-kontinuirno optimiranje oz. sintezo procesov. Objectives and competences: The main is to give concept of dynamic modeling and control of process units and (bio)chemical plants, and to present knowledge of discretecontinuous process optimization and synthesis. Predvideni študijski rezultati: Znanje in razumevanje: obvladovanje modeliranja, dinamike, regulacije in vodenja (bio)kemijskih procesov, obvladovanje teorije in aplikacij matematičnega programiranja pri načrtovanju, planiranju in obratovanju (bio)kemijskih procesov. Intended learning outcomes: Knowledge and Understanding: to have knowledge of modeling, dynamics and control of (bio)chemical processes, to understand theory and have knowledge of some practical applications of mathematical programming in designing, planning and operating (bio)chemical processes. Prenesljive/ključne spretnosti in drugi atributi: Imeti razumevanje o vplivu regulacijskih in optimizacijskih rešitev na varno, okolju prijazno in Transferable/Key Skills and other attributes: To have an understanding of the impact of control and optimization solutions on safe, environmentally 11 ekonomsko učinkovito delovanje kemijskih in biokemijskih procesov. benign and economically effective operation of chemical and biochemical processes. Metode poučevanja in učenja: Learning and teaching methods: Predavanja, seminar, laboratorijske in računalniške Lectures, seminar work, laboratory and computer vaje, samostojno delo študenta. practice, self-learning. Delež (v %) / Načini ocenjevanja: Weight (in %) Assessment: Izpit je opravljen, če so pozitivno Student has to pass successfully the opravljene vse naslednje obveznosti: following obligations: teoretični del izpita računski del izpita 30 70 Računski del izpita je mogoče nadomestiti z dvema računskima testoma. Teoretični del izpita je mogoče nadomestiti z dvema testoma teorije. Teoretični in računski del izpita/testa se izvajata sočasno. Theoretical part of exam Calculus part of exam Calculus part of the exam can be replaced by two calculus tests. Theoretical part of the exam can be replaced by two theoretical tests. Theory and calculus parts of the exam or test are performed simultaneously. Reference nosilca / Lecturer’s references: AHMETOVIĆ, Elvis, KRAVANJA, Zdravko. Simultaneous optimization of heat-integrated water networks involving process-to-process streams for heat integration. Applied thermal engineering, ISSN 1359-4311. [Print ed.], Jan. 2014, vol. 62, iss. 1, str. 302-217, doi: 10.1016/j.applthermaleng.2013.06.010. NEMET, Andreja, KLEMEŠ, Jiri, KRAVANJA, Zdravko. Designing a Total Site for an entire lifetime under fluctuating utility prices. Computers & chemical engineering, ISSN 0098-1354. [Print ed.], Available online 18 July 2014, vol. , str. 1-24, doi: 10.1016/j.compchemeng.2014.07.004. ČUČEK, Lidija, MARTÍN, Mariano, GROSSMANN, Ignacio E., KRAVANJA, Zdravko. Multi-period synthesis of optimally-integrated biomass and bioenergy supply network. Computers & chemical engineering, ISSN 0098-1354. [Print ed.], 4 Jul. 2014, vol. 66, str. 57-70, doi: 10.1016/j.compchemeng.2014.02.020. KRAVANJA, Zdravko, ČUČEK, Lidija. Multi-objective optimisation for generating sustainable solutions considering total effects on the environment. V: DUIĆ, Neven (ur.). Sustainable development of energy, water and environment systems, (Applied Energy, ISSN 0306-2619, Vol. 101, (2012)). Oxford: Elsevier, cop. 2012, vol. 101, str. 67-80, doi: 10.1016/j.apenergy.2012.04.025. ČUČEK, Lidija, KLEMEŠ, Jiri, KRAVANJA, Zdravko. A Review of Footprint analysis tools for monitoring impacts on sustainability. Journal of cleaner production, ISSN 0959-6526. [Print ed.], Oct. 2012, vol. 34, str. 9-20, doi: 10.1016/j.jclepro.2012.02.036. 12 Razvoj produktov in procesov Predmet: Course title: UČNI NAČRT PREDMETA / COURSE SYLLABUS Razvoj produktov in procesov Product and Process Development Študijski program in stopnja Study programme and level Kemijska tehnika / 2. stopnja Chemical Engineering / 2nd level Študijska smer Study field Letnik Academic year 1. Vrsta predmeta / Course type: Semester Semester letni Spring Obvezni / Obligatory Univerzitetna koda predmeta / University course code: Predavanja Lectures 30 Seminar Seminar Nosilec predmeta / Lecturer: Jeziki: Languages: Sem. vaje Tutorial 15 Lab. vaje Labor work Teren. vaje Field work Samost. delo Individ. work 135 ECTS 6 Zorka Novak Pintarič Predavanja / Lecture: slovenski / Slovene Vaje / Tutorial: slovenski / Slovene Pogoji za vključitev v delo oz. za opravljanje študijskih obveznosti: Pogojev ni. Prerequisites: Vsebina: - Uporaba matematike v tehniški ekonomiki. - Stopnje v sistematičnem razvoju produktov in procesov. - Dimenzioniranje in investicijsko vrednotenje procesne opreme. Vpliv inflacije na ceno. - Ocenjevanje investicije osnovnih sredstev. - Amortizacija. - Prihodki in obratovalni stroški. - Ocenjevanje investicije obratnih sredstev. - Statični in dinamični kriteriji ekonomske upravičenosti. - Analiza denarnih tokov. - Izbor med alternativami. - Inkrementalna ekonomska analiza. - Negotovost in tveganje pri ekonomski analizi. Content (Syllabus outline): - Mathematics in engineering economics. - Steps in systematic product and process development. - Equipment sizing and costing. Effect of inflation. - Fixed capital cost estimation. - Depreciation. - Annual sales revenues and production costs. - Working capital and total capital investment. - Static and dynamic profitability measures. - Cash flow analysis. - Selection between alternatives. - Incremental analysis. - Uncertainty and risk in economic evaluation. Vaje: - Priprava projektne dokumentacije. - Ocenjevanje investicije z računalniškimi programi in literaturnimi viri. None. Labor work: - Preparation of project documentation. 13 - Izdelava študije možnosti za izbrani proces. - Analize občutljivosti. - Študija primera: Načrtovanje kemijskega produkta - Evaluation of capital cost by applying advanced software tools and literature. - Feasibility study of the selected production plant. - Sensitivity analyses. - Case study: Design of chemical product Temeljni literatura in viri / Textbooks: Z. Novak Pintarič: Razvoj procesov v kemijski industriji, zbrano gradivo. Univerza v Mariboru, Fakulteta za kemijo in kemijsko tehnologijo, Maribor, 2014. http://www.fkkt.um.si/egradiva/fajli/Razvoj_procesov.pdf Z. Novak Pintarič: Razvoj produktov in procesov: zbirka nalog za računske vaje. Maribor: Fakulteta za kemijo in kemijsko tehnologijo, 2014. https://estudij.um.si/mod/resource/view.php?id=38331, http://dkum.uni-mb.si/IzpisGradiva.php?id=44464. [COBISS.SI-ID 17584150] Dodatna priporočena literatura: R. A. Brealey, S. C. Myers, A. J. Marcus: Fundamentals of Corporate Finance. Sixth Edition, McGraw Hill, New York, 2009. W. D. Seider, J. D. Seader, D. R. Lewin: Product and process design principles: synthesis, analysis, and evaluation. Second Edition, Wiley, New York, 2004. A. Chauvel, G. Fournier, C. Raimbault: Manual of Process Economic Evaluation. Editions Technip, Paris, 2003. Cilji in kompetence: Cilji tega predmeta so: - integracija znanj, ki jih dobijo študentje predhodno pri specifičnih tehniških predmetih, - obvladovanje stopenj v razvoju kemijskih in biokemijskih produktov in procesov, - osvojitev metodologije za pripravo študije možnosti in ocenjevanje ekonomske upravičenosti. Objectives and competences: The objectives of this course are: - integration of students' knowledge and skills acquainted by specific engineering subjects, - to acquire the steps in integral approach for development of chemical and biochemical products and processes, - to acquire the methodology for performing feasibility studies with economic evaluation. Predvideni študijski rezultati: Znanje in razumevanje: - poznavanje razvoja tehnološkega projekta od ideje do realizacije, - obvladovanje koncepta tehnološko-poslovnega odločitvenega procesa, - poznavanje pristopov in metod za pripravo študij možnosti, t.j. oceno investicije, obratovalnih stroškov, amortizacije in drugih odhodkov, - poznavanje kriterijev za oceno uspešnosti posameznega projekta, - sposobnost izbire med alternativnimi projekti. Prenesljive/ključne spretnosti in drugi atributi: - kreiranje idej in inovativnih tehnoloških rešitev, - uporabo strokovnih in znanstvenih informacijskih virov, - določevanje prioritet pri izvajanju projektov, - časovno planiranje in vodenje tehnoloških projektov, sprejemanje odločitev, - timsko delo pri razvoju tehnoloških projektov od ideje do realizacije, - izdelavo projektnih poročil in ustno komuniciranje o problematiki v globalnem tržnem Intended learning outcomes: Knowledge and Understanding: - integrate and use specific engineering knowledges by executing technical projects from the idea to realization, - understand the basic concepts of technologicalbussines decision making process, - prepare feasibility studies, evaluate investment cost, revenues, depreciation and operating costs, - calculate various profitability measures for evaluation of single project, - select between alternative projects. Transferable/Key Skills and other attributes: The student is able to: - create ideas and solve problems inventively, - use technical and scientific information sources, - determine priorities by executing the projects, - plan and manage technological projects, - team work for project development from idea to realization, - write reports, - present material oraly. 14 okolju. Metode poučevanja in učenja: Learning and teaching methods: - predavanja, - lectures, - računski in študijski primeri, domače naloge, - calculating examples, case studies, homeworks, - uporaba računalniških programov za ekonomske - use of computer tools in economic analyses analize, - active team work for peparation of project with - aktivno skupinsko delo za izdelavo projektne feasibility study. naloge s študijo možnosti. Delež (v %) / Načini ocenjevanja: Weight (in %) Assessment: Izpit je opravljen, če so pozitivno Student has to pass successfully the opravljene vse naslednje obveznosti: following obligations: - pisni računski izpit - izpit teorije - projektno poročilo 60 20 20 Izpit teorije se lahko izvaja ustno ali pisno. - written examination (calculus) - theory examination - written report on project work Theory examination can be performed orally or in writing. Reference nosilca / Lecturer’s references: NOVAK-PINTARIČ, Zorka, IBRIĆ, Nidret, AHMETOVIĆ, Elvis, GROSSMANN, Ignacio E., KRAVANJA, Zdravko. Designing optimal water networks for the appropriate economic criteria. V: 21st International Congress of Chemical and Process Engineering CHISA 2014 [and] 17th Conference PRES 2014, 23 - 27 August 2014, Praha, Czech Republic. Praha: [s. n.], 2014, 1 str. [COBISS.SI-ID 18099478] KASAŠ, Mihael, KRAVANJA, Zdravko, NOVAK-PINTARIČ, Zorka. Achieving profitably, operationally, and environmentally compromise flow-sheet designs by a single-criterion optimization. AIChE journal, ISSN 0001-1541. [Print ed.], July 2012, vol. 58, iss. 7, str. 2131-2141, doi: 10.1002/aic.12747. [COBISS.SI-ID 15215126] KASAŠ, Mihael, KRAVANJA, Zdravko, NOVAK-PINTARIČ, Zorka. Suitable modeling for process flow sheet optimization using the correct economic criterion. Industrial & engineering chemistry research, ISSN 0888-5885. [Print ed.], 2011, vol. 50, iss. 6, str. 3356-3370, doi: 10.1021/ie101485z. [COBISS.SI-ID 14805526] NOVAK-PINTARIČ, Zorka. Navodila za uporabo programa Aspen Process Economic Analyzer : za vaje pri predmetu Razvoj produktov in procesov. Maribor: Fakulteta za kemijo in kemijsko tehnologijo, 2014. [8] f., ilustr. https://estudij.um.si/mod/resource/view.php?id=38332,http://dkum.uni-mb.si/IzpisGradiva.php?id=44462. [COBISS.SI-ID 17584406] NOVAK-PINTARIČ, Zorka. Razvoj produktov in procesov: zbirka nalog za računske vaje. Maribor: Fakulteta za kemijo in kemijsko tehnologijo, 2014. [14] f., ilustr. https://estudij.um.si/mod/resource/view.php?id=38331, http://dkum.uni-mb.si/IzpisGradiva.php?id=44464. [COBISS.SI-ID 17584150] 15 Procesne naprave Predmet: Course title: UČNI NAČRT PREDMETA / COURSE SYLLABUS Procesne naprave Process Equipment Študijska smer Study field Študijski program in stopnja Study programme and level Letnik Academic year Semester Semester 1. letni Spring Kemijska tehnika / 2. stopnja Chemical Engineering / 2nd level Vrsta predmeta / Course type: Obvezni / Obligatory Univerzitetna koda predmeta / University course code: Predavanja Lectures Seminar Seminar Sem. vaje Tutorial 30 Nosilec predmeta / Lecturer: Jeziki / Languages: Lab. vaje Laboratory work 30 Teren. vaje Field work Samost. delo Individ. work ECTS 120 6 Darko Goričanec Predavanja / Lectures: slovenski / Slovene Vaje / Tutorial: slovenski / Slovene Pogoji za vključitev v delo oz. za opravljanje študijskih obveznosti: Osnovno znanje mehanike fluidov in prenosa toplote. Prerequisits: Vsebina: Content (Syllabus outline): Naprave za homogenizacijo tekočin - mešala in mešalne posode. Naprave za prenos tekočin: cevovodi, ventili, kompenzatorji, črpalke. Projekt pretočnega sistema za nevtralizacijo odpadnih vod. Naprave za prenos plinov: ventilatorji in kompresorji. Projekt prezračevanja digestorija in kompresorske postaje. Naprave za ločevanje tekočin – kolone. Vakuumski sistemi: pridobivanje vakuuma, nepropustnost, črpalke, ejektorji Toplotne črpalke. Naprave za centrifugiranje, filtracijo in sedimentacijo. Device for fluid homogenization – mixers and mixing vessels. Fluid transfer devices: pipes, valves, compensators, pumps. Project of fluid flow system for neutralising waste water. Gas transfer devices: ventilators and compressors Project for ventilation of digestories and compressor station. Devices for fluid separation - columns Vacuum systems: creating of vacuums, impermeability, pumps and ejectors Heat pumps Devices for centrifugation, filtration and sedimentation. Basic knowledge of fluid mechanics and heat transfer. 16 Projektno delo temelji na primerih, ki se navezujejo na predmet in krajši projektni nalogi. Project work is based on the chosen topic, regarding the theme of the subject and short process design project formulation. Temeljni literatura in viri / Readings: Goričanec, Darko, Krope, Jurij. Procesne naprave: zbrano gradivo pri predmetu Procesne naprave. Univerza v Mariboru, Fakulteta za kemijo in kemijsko tehnologijo, 2006. http://www.fkkt.um.si/egradiva/fajli/Procesne_naprave.pdf. Dodatna priporočena literatura: Charles E. Thomas: Process Technology Equipment and Systems, Cengage Learning; 4 edition, 2014. CAPT: Process Technology Equipment, Prentice Hall; 1 edition, 2009. Cilji in kompetence: Razviti sposobnost študentov za samostojno in kreativno reševanje inženirskih problemov. Razumevanje delovanja procesnih sistemov. Načrtovanje učinkovitejših procesnih sistemov. Objectives and competences: To further develop student's capabilities of independent thinking and creative solution of engineering problems. Understanding the functioning of process systems. Designing more efficient process systems. Predvideni študijski rezultati: Znanje in razumevanje: Razumevanje povezave različnih znanj in postopkov ter pomena uporabe strokovne literature za učinkovito reševanje inženirskih problemov. Intended learning outcomes: Knowledge and Understanding: Understanding of relationships between different skills and procedures and importance of professional literature for efficient solutions of process problems. Prenesljive/ključne spretnosti in drugi atributi: Kombinirana uporaba različnih naprednih znanj za reševanje inženirskih problemov Z mentorskim reševanjem konkretnih primerov se oblikuje študentova kreativnost in logično razmišljanje, potrebno za uspešno delo v praksi. Transferable/Key Skills and other attributes: Combined use of different fundamental skills for solution of engineering problems. Solving concrete examples under supervision and hence developing student’s creativity and logical thinking, needed for successful work in practice. Metode poučevanja in učenja: Predavanja: študent spozna teoretične vsebine predmeta. Laboratorijske vaje: študent utrdi teoretično znanje in spozna aplikativne možnosti reševanja primerov iz prakse, študent izdela krajšo študijo oz. projekt, ki se navezuje na tematiko predmeta. Learning and teaching methods: Lectures: the student gets acquainted with theoretical content of the subject. Laboratory work: the student upgrades the theoretical knowledge with practical experience, conducting a short study or project regarding the thematic of the subject. 17 Načini ocenjevanja: Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: seminarska naloga teoretični del izpita računski del izpita Delež (v %) / Weight (in %) 20 30 50 Teoretični in računski del tvorita celoto in se preverjata hkrati. Assessment: Student has to pass successfully the following obligations: seminar theoretical part of the exam calculation part of the exam The theoretical and the calculus part of the exam are performed simultaneously. Reference nosilca / Lecturer’s references: GORIČANEC, Darko, POZEB, Viljem, TOMŠIČ, Ladislav, TROP, Peter. Exploitation of the waste-heat from hydro power plants. Energy, ISSN 0360-5442. [Print ed.], Available online 22 July 2014, str. 1-6. ANICIC, B., TROP, Peter, GORIČANEC, Darko. Comparison between two methods of methanol production from carbon dioxide. Energy, ISSN 0360-5442. [Print ed.], 2014, 77, str. 279-289, doi: 10.1016/j.energy.2014.09.069. [COBISS.SI-ID 80681729]. DOBERŠEK, Danijela, GORIČANEC, Darko, KROPE, Jurij. Dryers for sewage sludge dehydration. International journal of energy and environment, 2012, vol. 6, iss. 6, str. 588-596. http://www.naun.org/multimedia/NAUN/energyenvironment/16-691.pdf. [COBISS.SI-ID 16535062]. KULČAR, Bojan, GORIČANEC, Darko, KROPE, Jurij. Economy of replacing a refrigerant in a cooling system for preparing chilled water = Remplacement du frigorigene dans un systeme utilisé pour préparer de l'eau glacée : impact financier. International journal of refrigeration, ISSN 0140-7007. [Print ed.], Aug. 2010, vol. 33, iss. 5, str. 989-994. ŽLAK, Janez, AGREŽ, Marko, DOBERŠEK, Danijela, GORIČANEC, Darko, KROPE, Jurij. Rentability of rotary heat regenerator use in ventilating systems = Rentabilnost upotrebe regeneratora topline u ventilacijskom sustavu. Strojarstvo, ISSN 0562-1887, 2010, vol. 52, no. 6, str. 665-671. [COBISS.SI-ID 15454486]. 18 Bioseparacijska tehnika in biokataliza Predmet: Course title: UČNI NAČRT PREDMETA / COURSE SYLLABUS Bioseparacijska tehnika in biokataliza Bioseparation Processes and Biocatalysis Študijski program in stopnja Study programme and level Kemijska tehnika / 2. stopnja Chemical Engineering / 2nd level Študijska smer Study field Letnik Academic year 1. Vrsta predmeta / Course type: Semester Semester letni Spring Obvezni / Obligatory Univerzitetna koda predmeta / University course code: Predavanja Lectures 45 Seminar Seminar Nosilec predmeta / Lecturer: Jeziki / Languages: Sem. vaje Tutorial Lab. vaje Labor work 30 Teren. vaje Field work Samost. delo Individ. work 105 ECTS 6 Željko Knez, Maja Leitgeb Predavanja / Lecture: slovenski / Slovene Vaje / Tutorial: slovenski / Slovene Pogoji za vključitev v delo oz. za opravljanje študijskih obveznosti: Potrebno je znanje separacijske tehnike ter osnovno znanje biokemije, biokemijske tehnike in biotehnologije. Prerequisites: Vsebina: - Bioseparacijska tehnika: Separacija (flokulacija in flotacija, filtracija, centrifugiranje), koncentriranje (ekstrakcija, membranski procesi), sušenje. - Biokataliza: kinetika biokataliziranih reakcij, določevanje kinetičnih parametrov, imobilizacija biokatalizatrojev, modeliranje biokataliziranih reakcij. Content (Syllabus outline): - Bioseparation processes: Separation (flocculation and flotation, filtration, centrifugation), concentration (extraction, membrane processes), drying. - Biocatalysis: kinetic of biocatalyzed reactions, determination of kinetic parameters,immobilization of biocatalysts, modelling of biocatalyzed reactions. Knowledge of separation processes and basic knowledge of biochemistry, biochemical engineering and biotechnooogy is needed. Project will be based on experimental work from the field of biocatalytic processes, integrated with bioseparation processes. Projektno delo bo potekalo na osnovi laboratorijskih eksperimentov s področja biokatalitičnih procesov, kjer bodo istočasno zajeti tudi bioseparacijski procesi. 19 Temeljni literatura in viri / Textbooks: B. Elvers, S. Hawkins, W. E Russey: Ullmann's encyclopedia of industrial chemistry, izbrana poglavja, Weinheim, Cambridge: Wiley-VCH, 2003. Dodatna priporočena literatura: M. C. Flickinger, Upstream and Downstream Industrial Biotechnology, 3V Bundle, Wiley, ISBN: 978-1118-13125-1, 2014. M. C. Flickinger, Encyclopedia of Industrial Biotechnology, Bioprocess, Bioseparation, and Cell Technology , 7 Volume Set, Wiley, ISBN: 978-0-471-79930-6, 2010. A. Illanes, L. Wilson, C. Vera, Problem Solving in Enzyme Biocatalysis, Wiley, ISBN: 978-1-118-34171-1, 2013. J. A. Tao, R. J. Kazlauskas, Biocatalysis for Green Chemistry and Chemical Process Development, Wiley, ISBN: 978-0-470-43778-0, 2011. Cilji in kompetence: Na osnovi projektnega dela spoznati bioseparacijske metode ter poglobljena znanja iz biokatalize. Objectives and competences: On the basis of project work the sudets will get the knowledge about bioseparation processes, as well as advanced knowledge of biocatalysis. Predvideni študijski rezultati: Znanje in razumevanje: Zmožnost načrtovanja biokatalitskega sistema; uporaba ustreznih bioseparacijskih metod v povezavi z biokataliziranim sistemom. Intended learning outcomes: Knowledge and Understanding: Design of biocatalytic systems; application of bioseparation processes for a defined biocatalytic system. Prenesljive/ključne spretnosti in drugi atributi: Vsebina predmeta je povezana z ostalimi predmeti na smeri Biokemijska tehnika in podaja znanja, ki so nujno potrebna za razumevanje vsebin, ki so zajete pri predmetih Industrijska mikrobiologija in Bioreakcijska tehnika. Transferable/Key Skills and other attributes: The subject is strongly connected to the other subjects on the direction Biochemical engineering and gives the knowledge which is necessarry for understanding other subjects, such as Industrial microbiology and Bioreaction engineering. Metode poučevanja in učenja: Predavanja v učilnici, ki je opremljena z avdiovizualnimi pripomočki. Learning and teaching methods: Lectures in lecture room, equipped with audio-visual equipment Individualna priprava projektne naloge s predstavitvijo in diskusijo. Individual preparation of project work with the presentation with discussion. Načini ocenjevanja: Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: - ustni izpit - projektno poročilo - predstavitev projekta Delež (v %) / Weight (in %) 50 25 25 20 Assessment: Student has to pass successfully the following obligations: - oral examination - project written report - project oral presentation Reference nosilca / Lecturer’s references: KNEZ, Željko, KAVČIČ, Sabina, GUBICZA, László, BÉLAFI-BAKÓ, Katalin, NÉMETH, Gergely, PRIMOŽIČ, Mateja, LEITGEB, Maja. Lipase-catalyzed esterification of lactic acid in supercritical carbon dioxide. The Journal of supercritical fluids, ISSN 0896-8446. 2012, 66, 192-197, doi: 10.1016/j.supflu.2011.11. [COBISS.SI-ID 15598102] ŠULEK, Franja, PÉREZ FERNÁNDEZ, Daniel, KNEZ, Željko, LEITGEB, Maja, SHELDON, Roger A. Immobilization of horseradish peroxidase as crosslinked enzyme aggregates (CLEAs). Process biochemistry, ISSN 1359-5113, 2011, 46 (3), 765-769, doi: 10.1016/j.procbio.2010.12.001. [COBISS.SI-ID 14712598] CSANÁDI, Zsófia, BÉLAFI-BAKÓ, Katalin, SZENTGYÖRGYI, Eszter, GUBICZA, László, KNEZ, Željko, LEITGEB, Maja. Enzymatic esterification of glycerol and stearic acid in non-conventional media. Acta chimica slovenica, ISSN 13180207. 2010, 57 (1), 244-249. COBISS.SI-ID 14029590] ŠULEK, Franja, KNEZ, Željko, LEITGEB, Maja. Immobilization of cholesterol oxidase to finely dispersed silica-coated maghemite nanoparticles based magnetic fluid. Applied Surface Science, ISSN 0169-4332. 2010, 256 (14), 45964600. [COBISS.SI-ID 14055446] THOREY, Paul, KNEZ, Željko, LEITGEB, Maja. Alcohol dehydrogenase in non-aqueous media using high-pressure technologies : reaction set-up and deactivation determination. Journal of chemical technology and biotechnology, ISSN 0268-2575. 2010, 85, 1011-1016. [COBISS.SI-ID 14291222] 21 Bioreakcijska tehnika UČNI NAČRT PREDMETA / COURSE SYLLABUS Bioreakcijska tehnika Bioreaction Engineering Predmet: Course title: Študijski program in stopnja Study programme and level Kemijska tehnika / 2. stopnja Chemical Engineering / 2nd level Študijska smer Study field Letnik Academic year 1. Vrsta predmeta / Course type: Semester Semester letni Summer Obvezni / Obligatory Univerzitetna koda predmeta / University course code: Predavanja Lectures 30 Seminar Seminar Nosilec predmeta / Lecturer: Jeziki / Languages: Sem. vaje Tutorial Lab. vaje Labor work 30 Teren. vaje Field work amost. delo Individ. work 120 ECTS 6 Andreja Goršek Predavanja / Lecture: slovenski / Slovene Vaje / Tutorial: slovenski / Slovene Pogoji za vključitev v delo oz. za opravljanje študijskih obveznosti: Potrebna so osnovna znanja termodinamike, biokemije, biokemijske in reakcijske tehnike. Prerequisites: Vsebina: Predavanja: Uvodni pojmi. Bioreakcijska kinetika (encimska in mikrobiološka). Tipi bioreaktorjev: osnovni (mešalni, kolonski, z dvigovanjem zraka) in posebni tipi. Tehnološke zahteve pri načrtovanju bioreaktorjev (mešanje, snovni in toplotni prenos). Modeliranje biokemijskih reakcijskih sistemov (šaržni, pretočni, kaskada pretočnih bioreaktorjev, šaržni z dotokom substrata). Ekonomika bioprocesov. Content (Syllabus outline): Lectures: Fundamentals. Bioreaction kinetics (enzymatic and microbial) Type of bioreactors: basic (mixed, bubble column, airlift) and special types. Technological requirements in bioreactor design (mixing, mass transfer, heat transfer). Modeling of biochemical reaction systems (batch, continuous, continuous in series, fed-batch). Bioprocess economics Laboratorijske vaje: Poudarek je na načrtovanju bioreaktorjev: aerobni reaktor anaerobni reaktor aeracijska enota Laboratorial exercises: The main emphasis is focused on bioreactor design: aerobic reactor anaerobic reactor aeration unit Basic knowledge about thermodynamics, biochemistry and reaction engineering is required. 22 Projektno delo: Študentje izberejo bioproces, ga analizirajo in pripravijo predstavitev. Project work: Student choose a bioprocess, perform the analysis and prepare public presentation. Temeljni literatura in viri / Textbooks: A. Goršek. Bioreakcijska tehnika: zbrano gradivo, http://www.fkkt.um.si/egradiva/fajli/brt.pdf, 2007. M. Tramšek, A. Goršek, Bioreakcijska tehnika: navodila za laboratorijske vaje, UM FKKT, 2005. Levenspiel, Chemical Reaction Engineering, John Wiley & Sons, New York, 1999. Dodatna priporočena literatura: P. M. Doran, Bioprocess Engineering Principles, Elsevier Ltd., London, 2004. I. J. Dunnn, E. Heinzle, J. Ingham, J.E. Prenosil, Biological reaction Engineering, Dinamic Modelling Fundamentals with Simulation Examples, Wiley-VCH, Weinheim, 2003. Cilji in kompetence: Vključevanje principov kemijske reakcijske tehnike v biokemijske sisteme. Predstavitev različnih tipov, konfiguracij in aplikacij bioreaktorjev ter fermentorjev. Seznanitev z osnovnimi in kompleksnejšimi biokinetičnimi modeli ter njihovo uporabo pri modeliranju šaržnih, semikontinuiranih in kontinuiranih bioreaktorskih sistemov. Objectives and competences: Incorporating the principles of chemical reaction engineering in biochemical systems. Presenting the different types, configurations and applications of bioreactors and fermentors. Introducing the basic and complex biokinetic models and their application in modeling of batch, semicontinuous and continuous bioreactor systems. Predvideni študijski rezultati: Znanje in razumevanje: Razumevanje principov encimskih in mikrobnih reakcij. Poznavanje stehiometrije, in kinetike biokemijskih reakcij. Poznavanje snovnih bilanc bioprocesov v dinamičnem ter stacinarnem stanju. Dinamično modeliranje različnih tipov bioreaktorjev. Intended learning outcomes: Knowledge and Understanding: Understanding the principles of enzymatic and microbial reactions. Knowledge the stehiometry and kinetics of biochemical reactions. Knowledge of the unsteady and steady-state material balances of bioprocesses. Dynamic modeling of different bioreactor types. Prenesljive/ključne spretnosti in drugi atributi: Modeliranje mikrobiološke rasti in encimskih reakcij z ali brez inhibicije. Izvajanje osnovnih tehnoloških izračunov za načrtovanje bioreaktorjev, upoštevajoč velikost, mešalni režim in kapaciteto snovnega prenosa. Transferable/Key Skills and other attributes: Modeling of microbial growth and enzymatic reactions with or without inhibition. Executing of basic reaction engineering calculations for bioreactors design including size, stirrer regime and mass transfer capacity. Metode poučevanja in učenja: Predavanja, obogatena z računskimi primeri, multimedijskim materialom (simulacije, slike, diagrami) in primeri iz industrije. Pomoč pri reševanju računskih nalog. Individualno delo – priprava projekta in javna predstavitev. Pomoč pri iskanju biokemijskih informacij in podatkov na spletu ter drugih elektronskih virih. Pisno reševanje nalog. Learning and teaching methods: Lectures, enriched with numerical problems, multimedia material (simulations, pictures, diagrams) and case studies from industry Helping students at solving numerical problems. Individual work – project preparation and public presentation. Helping students with biochemical data searching on internet and other electronic sources. Written test on problem solving skills. 23 Načini ocenjevanja: Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: pisno poročilo o laboratorijskih vajah projektno poročilo pisni izpit Delež (v %) / Weight (in %) 30 20 50 Assessment: Student has to pass successfully the following obligations: laboratory work written report project report written exam Reference nosilca / Lecturer’s references: ZAJŠEK, Katja, KOLAR, Mitja, GORŠEK, Andreja. Characterisation of the exopolysaccharide kefiran produced by lactic acid bacteria entrapped within natural kefir grains. International journal of dairy technology, ISSN 1364-727X, 2011, vol. 64, issue 4, str. 544-548, doi: 10.1111/j.1471-0307.2011.00704.x. [COBISS.SI-ID 15278870]. ZAJŠEK, Katja, GORŠEK, Andreja. Experimental assessment of the impact of cultivation conditions on kefiran production by the mixed microflora imbedded in kefir grains. V: 9th International Conference on Chemical and Process Engineering, 8-11 May, 2011, Florence, Italy. PIERUCCI, Sauro (ur.). ICheaP-10, (Chemical Engineering transactions, ISSN 1974-9791, Vol. 24). Milano: AIDIC, 2011, str. 481-486, doi: 10.3303/CET1124081. [COBISS.SI-ID 14955798]. PEČAR, Darja, SLEMNIK, Mojca, GORŠEK, Andreja. Testing the corrosion resistance of stainless steels during the fermentation of probiotic drink. Journal of the Science of Food and Agriculture, ISSN 0022-5142, May 2011, vol. 91, iss. 7, str. 1293-1297, doi: 10.1002/jsfa.4315. [COBISS.SI-ID 14809622]. ZAJŠEK, Katja, GORŠEK, Andreja, KOLAR, Mitja. Cultivating conditions effects on kefiran production by the mixed culture of lactic acid bacteria imbedded within kefir grains. Food chemistry, ISSN 0308-8146. [Print ed.], Jan. 2013, vol. 139, iss. 1-4, str. 970-977, doi: 10.1016/j.foodchem.2012.11.142. [COBISS.SI-ID 16645142]. VNUČEC, Doroteja, GORŠEK, Andreja, KUTNAR, Andreja, MIKULJAN, Marica. A new method of physical modification of soy proteins for wood adhesives. V: International conference on wood adhesives : 9-11 october, 2013, Toronto, Ontario, Canada. [Madison]: Forest Products Society, 2014, str. 570-576, ilustr. [COBISS.SI-ID 1536529092]. 24 Načrtovanje procesov - projekt Predmet: Course title: UČNI NAČRT PREDMETA / COURSE SYLLABUS Načrtovanje procesov - projekt Process Design - Project Načrtovanje procesov - projekt Študijski program in stopnja Study programme and level Kemijska tehnika / 2. stopnja Chemical Engineering / 2nd level Študijska smer Study field Kemijska tehnika Chemical Engineering Vrsta predmeta / Course type: Letnik Academic year 1. Semester Semester letni Spring Obvezni / Obligatory Univerzitetna koda predmeta / University course code: Predavanja Lectures Seminar Seminar Nosilec predmeta / Lecturer: Jeziki / Languages: Sem. vaje Tutorial 45 Lab. vaje Labor work Teren. vaje Field work Samost. delo Individ. work 135 ECTS 6 Zorka Novak Pintarič Predavanja / Lecture: Vaje / Tutorial: slovenski / Slovene Pogoji za vključitev v delo oz. za opravljanje študijskih obveznosti: Potrebno je znanje iz termodinamike, prenosa toplote in snovi ter osnovno znanje iz separacijske in reakcijske tehnike. Prerequisites: Vsebina: Računalniške vaje - projekt: Izbor procesa, sinteza procesne sheme. Simulacija procesa z rigoroznimi modeli in termodinamiko. Termodinamska analiza, toplotna integracija, načrtovanje omrežja toplotnih prenosnikov. Ekonomsko in okoljsko vrednotenje procesa. Priprava projektnega poročila. Ustna predstavitev projekta. Content (Syllabus outline): Computer Exercises - project: Selection of process, synthesis of process flow sheet. Process simulation using rigorous models and thermodynamics. Thermodynamic analysis, heat integration, Heat Exchanger Network design. Process economics and environmental evaluation. Preparation of written project report. Oral presentation of project. Knowledge of thermodynamics, heat and mass transfer and basic knowledge of separation and reaction engineering is required. Temeljni literatura in viri / Textbooks: Z. Novak Pintarič, Načrtovanje in integracija procesov, zbrano gradivo. Univerza v Mariboru, Fakulteta za kemijo in kemijsko tehnologijo, Maribor, 2014. Z. Novak Pintarič, Simulacija kemijskih procesov, zbrano gradivo. Univerza v Mariboru, Fakulteta za kemijo in kemijsko tehnologijo, Maribor, 2014. M. Bogataj, A. Goršek, P. Glavič, Načrtovanje procesov, Navodila za vaje, Univerza v Mariboru, Fakulteta za kemijo in kemijsko tehnologijo, Maribor, 2005. Dodatna priporočena literatura: 25 R. Smith, Chemical Process Design and Integration, J. Wiley, 2005. J. J. Klemeš (Ed.), Handbook of Process Integration (PI), Woodhead Publishing, Cambridge, 2013. Cilji in kompetence: Sinteza znanj iz kemije, termodinamike, osnovnih pojavov in operacij, varnosti in okolja, ekonomike Objectives and competences: Synthesis of knowledge, acquired in: chemistry, basic phenomena, thermodynamics, unit operations, safety, environmental protection, economics, etc. Predvideni študijski rezultati: Znanje in razumevanje: Konceptualno načrtovanje procesov, toplotna integracija. Povezovanje pridobljenih znanj. Razširitev znanja na kompleksne procese (več procesnih enot). Intended learning outcomes: Knowledge and Understanding: Conceptual process design, heat integration. Linking the acquired knowledge. Knowledge extension to complex processes (more process units). Prenesljive/ključne spretnosti in drugi atributi: Računalniško načrtovanje zahtevnejših celotnih procesnih shem. Razvijanje sposobnosti za skupinsko in projektno delo. Transferable/key skills and other attributes: Computer aided design and retrofit of more complex total process systems. Abilities to work in team. Experience in executing large projects. Metode poučevanja in učenja: Uporaba tujih jezikov in literature. Skupinske računalniške vaje simuliranja, integriranja, načrtovanja, optimiranja procesa, ekonomskega vrednotenja investicij. Pisanje in zagovor skupinskega projektnega poročila. Learning and teaching methods: Usage of foreign languages and literature. Team-work in process simulation, integration, design, optimization, and economic evaluation of the investment. Writing and defence of the team design report. Načini ocenjevanja: Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: - projektno delo - projektno poročilo - predstavitev projekta Delež (v %) / Weight (in %) 10 60 30 Assessment: Student has to pass successfully the following obligations: - computer exercises - project work and report - project presentation Reference nosilca / Lecturer’s references: NOVAK-PINTARIČ, Zorka, KRAVANJA, Zdravko. Suitable process modelling for proper multi-objective optimization of process flow sheets. V: KLEMEŠ, Jiri (ur.), VARBANOV, Petar (ur.), LIEW, Peng Yen (ur.). 24th European Symposium on Computer Aided Process Engineering : [ESCAPE-24, 15 to 18 June 2014, Budapest, Hungary], (Computer aided chemical engineering, ISSN 1570-7946, 33). Amsterdam ... [et al.]: Elsevier, cop. 2014, str. 13881392. [COBISS.SI-ID 18172438] KRAVANJA, Zdravko, NOVAK-PINTARIČ, Zorka, SIMONIČ, Marjana, ŠKOF, Gorazd. Optimizacija obstoječe in načrtovanje nove naprave za čiščenja odpadnih oljnih emulzij : zaključno poročilo projekta. Maribor: Fakulteta za kemijo in kemijsko tehnologijo, Laboratorij za procesno sistemsko tehniko in trajnostni razvoj, 2013. 53 str., ilustr. [COBISS.SI-ID 17120534] TOKOS, Hella, NOVAK-PINTARIČ, Zorka, GLAVIČ, Peter. Energy saving opportunities in heat integrated beverage plant retrofit. Applied thermal engineering, ISSN 1359-4311. [Print ed.], Jan. 2010, vol. 30, no. 1, str. 36-44, doi: 10.1016/j.applthermaleng.2009.03.008. [COBISS.SI-ID 13122838] NOVAK-PINTARIČ, Zorka. Načrtovanje in integracija procesov : zbrano gradivo za predmet Načrtovanje procesov na bolonjskem magistrskem programu Kemijska tehnika. Maribor: Fakulteta za kemijo in kemijsko tehnologijo, 2014. [145] f., ilustr. https://estudij.um.si/mod/resource/view.php?id=21344, http://dkum.unimb.si/IzpisGradiva.php?id=44461. [COBISS.SI-ID 17583638] 26 NOVAK-PINTARIČ, Zorka. Simulacija kemijskih procesov : zbrano gradivo za vaje pri predmetu Načrtovanje procesov na bolonjskem magistrskem programu Kemijska tehnika. Maribor: Fakulteta za kemijo in kemijsko tehnologijo, 2014. [37] f., ilustr. https://estudij.um.si/mod/resource/view.php?id=21375, http://dkum.unimb.si/IzpisGradiva.php?id=44466. [COBISS.SI-ID 17583894] 27 Industrijska mikrobiologija Predmet: Course title: UČNI NAČRT PREDMETA / COURSE SYLLABUS Industrijska mikrobiologija Industrial Microbiology Študijski program in stopnja Study programme and level Kemijska tehnika / 2. stopnja Chemical Engineering / 2nd level Študijska smer Study field Biokemijska tehnika Biochemical Engineering Vrsta predmeta / Course type Letnik Academic year 1. Semester Semester letni Summer Obvezni / Obligatory Univerzitetna koda predmeta / University course code: Predavanja Lectures 30 Seminar Seminar Nosilec predmeta / Lecturer: Jeziki / Languages: Sem. vaje Tutorial Lab. vaje Labor work 15 Teren. vaje Field work Samost. delo Individ. work 135 ECTS 6 Maja Leitgeb Predavanja / Lecture: slovenski / Slovene Vaje / Tutorial: slovenski / Slovene Pogoji za vključitev v delo oz. za opravljanje študijskih obveznosti: Potrebno je znanje iz separacijske tehnike ter osnovno znanje mikrobiologije, biokemije, biokemijske tehnike in biotehnologije. Prerequisites: Vsebina: Definicija industrijske mikrobiologije. Oprema za fermentacijo in njena uporaba. Rast in nastajanje produktov; gojenje celic, celična kinetika. Kinetka biokataliziranih reakcij z dvema ali več substrati. Detekcija in analiza fermentacijskih produktov (fizikalno-kemijske in biološke analize). Fermentacijski mediji: sestava, sterilizacija, kontaminacija, cepitev, analiza. Sterilizacija (šaržna, kontinuirana, sterilizacija zraka). Downstream processing (separacija, razbitje celic, izolacija produktov in njihovo čiščenje). Industrijski mikroorganizmi. Industrijski procesi in produkti: Mikrobni encimi. Content (Syllabus outline): Definition of industrial microbiology. Fermentation equipment and its use. Industrial microorganisms and products. Inoculum preparation. Kinetic of biocatalyzed reactions with two or more substrates. Detection and assay of fermentation products (physical – chemical assays and biological assays). Fermentation media (composition, sterilization and contamination, inoculum media). Sterilization (batch, continuous, sterilization of air). Industrial microorganisms. Downstream processing (separation, product isolation, ...). Industrial microorganisms. Industrial processes and products: Microbial enzymes. Knowledge of separation processes and basic knowledge of microbiology, biochemistry, biochemical engineering and biotechnology is needed. 28 Antibiotiki: penicilin, streptomicin, drugi antibiotiki. Anaerobne fermentacije. Glicerol. Vitamini. Indirektna in direktna fermentacija. Mikrobna oksidativna transformacija substrata: vinski kis, glukonska kislina. Mikrobne celice kot fermentacijski produkti (pekovski kvas, kvas za prehrano in krmo, bakterijski insekticidi, glive, alge). Organske kisline: citronska kislina, fumarna kislina. Genska kontrola metabolnih poti. Laboratorijske vaje s področja sterilizacije in fermentacijskih procesov. Antibiotic fermentations (penicillin, streptomycin, and others). Anaerobic fermentations. Glycerol. Vitamins. Indirect and direct fermentation. Microbial oxidative transformations of substrate: vinegar, gluconic acid. Microbial cells as fermentation products (bakers’ yeast, food and feed yeasts, bacterial insecticides, mushrooms, algae). Organic acids (citric acid, fumaric acid). Genetic control of metabolic pathways. Laboratory work in the field of sterilization and fermentation processes. Temeljni literatura in viri / Textbooks: M. J. Waites, N. L. Morgan, J. S. Rockey, G. Highton, Industrial Microbiology, Blackwell Publishing, London, 2004. Dodatna priporočena literatura: L. E. Casida, Industrial microbiology, John Wiley and Sons, New York, 2003. M. T. Madigar, J. M. Martinko, D. Stahl, D. P. Clark, Brock Biology of Microorganisms, 13 th ed., Prentice Hall, London, 2010. Murray R. K., Granner D. K., Mayes P. A., Rodwell V. W. Harper’s Biochemistry, 24th ed. Prentice Hall, London, 2010. G. Lear, G. D. Lewis, Microbial Biofilms: Current Research and Applications, Caister Academic Press, New Zealand, 2012. Cilji in kompetence: Pregled znanj s področja industrijske mikrobiologije; od izolacije kultur, njihove ohranitve, proizvodnje določenih produktov, do načrtovanja fermentacijskih procesov. Objectives and competences: Overview of knowledge in the field of industrial microbiology; from isolation of cultures, their preservation, production of desired products, to design of fermentation processes. Predvideni študijski rezultati: Znanje in razumevanje: Uporaba mikroorganizmov z njihovimi zelo različnimi metabolnimi aktivnostmi za industrijske aplikacije – procese in produkte z visoko ekonomskim, okoljskim in socialnim pomenom. Intended learning outcomes: Knowledge and Understanding: The use of microorganisms, with their extremely diverse metabolic activities, for industrial applications – processes and products that are of major economic, environmental and social importance. Prenesljive/ključne spretnosti in drugi atributi: Predmet se dopoljnjuje z ostalimi vsebinami smeri Biokemijska tehnika. Transferable/Key Skills and other attributes: The subject is related to the other subjects on the study field Biochemical engineering. Metode poučevanja in učenja: Predavanja v učilnici, ki je opremljena z avdiovizualnimi pripomočki. Individualna priprava seminarskih nalog s predstavitvijo in diskusijo. Laboratorijsko delo na izbranem primeru. Learning and teaching methods: Lectures in lecture room, equipped with audio-visual equipment Individual preparation of seminars and their presentation with discussion. Laboratory work on selected case. 29 Načini ocenjevanja: Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: - laboratorijske vaje (dnevnik, kolokvij) - pisni izpit - ustni izpit Delež (v %) / Weight (in %) 20 40 40 Assessment: Student has to pass successfully the following obligations: - completed lab work (report, colloquium) - written examination - oral examination Reference nosilca / Lecturer’s references: LEITGEB, Maja, ČOLNIK, Maja, PRIMOŽIČ, Mateja, ZALAR, Polona, GUNDE-CIMERMAN, Nina, KNEZ, Željko. Activity of cellulase and [alpha]-amylase from Hortaea werneckii after cell treatment with supercritical carbon dioxide. The Journal of supercritical fluids, ISSN 0896-8446. 2013, 78, 143-148, doi: 10.1016/j.supflu.2013.03.029. [COBISS.SI-ID 16864790] ČOLNIK, Maja, PRIMOŽIČ, Mateja, KNEZ, Željko, LEITGEB, Maja. Use of supercritical carbon dioxide for proteins and alcohol dehydrogenase release from yeast Saccharomyces cerevisiae. The Journal of supercritical fluids, ISSN 08968446. 2012, 65, 11-17, doi: 10.1016/j.supflu.2012.02.018. [COBISS.SI-ID 15901462] KNEZ, Željko, KAVČIČ, Sabina, GUBICZA, László, BÉLAFI-BAKÓ, Katalin, NÉMETH, Gergely, PRIMOŽIČ, Mateja, LEITGEB, Maja. Lipase-catalyzed esterification of lactic acid in supercritical carbon dioxide. The Journal of supercritical fluids, ISSN 0896-8446. 2012, 66, 192-197, doi: 10.1016/j.supflu.2011.11. [COBISS.SI-ID 15598102] ŠULEK, Franja, PÉREZ FERNÁNDEZ, Daniel, KNEZ, Željko, LEITGEB, Maja, SHELDON, Roger A. Immobilization of horseradish peroxidase as crosslinked enzyme aggregates (CLEAs). Process biochemistry, ISSN 1359-5113, 2011, 46 (3), 765-769, doi: 10.1016/j.procbio.2010.12.001. [COBISS.SI-ID 14712598] KAVČIČ, Sabina, KNEZ, Željko, LEITGEB, Maja. Antimicrobial activity of n-butyl lactate obtained via enzymatic esterification of lactic acid with n-butanol in supercritical trifluoromethane. The Journal of supercritical fluids, ISSN 0896-8446. 2014, 85, 143-150, doi: 10.1016/j.supflu.2013.11.003. [COBISS.SI-ID 17392406] 30 Pripravljalni in zaključni procesi Predmet: Course title: UČNI NAČRT PREDMETA / COURSE SYLLABUS Pripravljalni in zaključni procesi Upstream / Downstream Processes Študijski program in stopnja Study programme and level Študijska smer Study field Letnik Academic year Semester Semester Kemijska tehnika / 2. stopnja Chemical Engineering / 2nd level Kemijska tehnika Chemical engineering 2. zimski Autumn Vrsta predmeta / Course type: Obvezni / Obligatory Univerzitetna koda predmeta / University course code: Predavanja Lectures Seminar Seminar Sem. vaje Tutorial 30 Nosilec predmeta / Lecturer: Jeziki / Languages: Lab. vaje Laboratory work 30 Teren. vaje Field work Samost. delo Individ. work ECTS 120 6 Željko Knez Predavanja / Lectures: slovenski / Slovene Vaje / Tutorial: slovenski / Slovene Pogoji za vključitev v delo oz. za opravljanje študijskih obveznosti: Pojmi in osnovna znanja s področij industrijske stehiometrije, energetske bilance kemijskih sistemov in proizvodnje produktov. Prerequisits: Basic knowledege in the field of industrial stochiometry, energetic balance of chemical systems and production of products. Vsebina: Osnove industrijskih pripravljalnih in zaključnih procesov za različne vrste produktov. Načrtovanje in razvoj strategij pripravljalnih in zaključnih procesov; Primerjava pripravljalnih in zaključnih procesov. Različni separacijski tehnološki postopki (uparjanje, centrifugiranje, konvencionalna in membranska filtracija, postopki obarjanja, kristalizacija, procesna kromatografija, ...) in njihova učinkovitost. Izhodišča raziskav (case study) in razvoj celotnega procesa. Content (Syllabus outline): General introduction to industrial downstream and upstream processes for different products. Process design and development of downstream processing (upstream versus downstream). Different separation technological processes (evaporation, centrifugation, conventional and membrane filtration, precipitation processes, crystallization, process chromatography,...) and their effectiveness. Case studies and development of the complete process. V okviru laboratorijskih vaj se izvaja superkritična Laboratory work includes supercritical extraction, antimicrobial activity of extract, micronisation, 31 ekstrakcija, protibakterijsko delovanje ekstrakta, mikronizacija, superkritična kormatografija. supercritical chromatography. Temeljni literatura in viri / Readings: B. Elvers, S. Hawkins, W. E Russey: Ullmann's encyclopedia of industrial chemistry, izbrana poglavja, Weinheim, Cambridge: Wiley-VCH, 2003. Dodatna priporočena literatura: J. Nielsen, J. Villadsen, G. Liden, Bioreaction Engineering Principles, 2nd ed., Kluwer Academic/Plenum Publishers, 2003. M. C. Flickinger, Downstream Industrial Biotechnology: Recovery and Purification, Wiley, 2013, ISBN: 978-1-118-13124-4. Cilji in kompetence: - Priprava surovin in obdelava produktov v industriji. - Pravilna razporeditev produktnih enot za obdelavo (čiščenje) določenega produkta. - Povezava med pripravljalnimi in zaključnimi procesi. - Pomembnost čistote produkta v razvoju in načrtovanju v pripravljalnih procesih. - Obdelava (študij) rezultatov realnih primerov in njihova uporaba za izbiro procesnih pogojev za določeno operacijo. - Izračun operativnih parametrov za določeno operacijsko enoto pripravljalnega procesa. Objectives and competences: - Preparation of raw materials and product processing in industry. - Appropriate arrangement of unit operations for the processing (purification) of a given type of a product. - Interplay between upstream and downstream processes. - Importance of product purity during development and planning of upstream processes. - Results processing (study) of real examples and their use for the selection of process conditions for specific operation. - Calculation of operating parameters for a given downstream unit operation process. Predvideni študijski rezultati: Znanje in razumevanje: Zmožnost načrtovanja pripravljalnih in zaključnih procesov za komercialno pomembne substance. Intended learning outcomes: Knowledge and understanding: The ability to design of upstream / downstream processes for commercially important compounds. Prenesljive/ključne spretnosti in drugi atributi: Vsebina predmeta je povezana z ostalimi predmeti na smeri Kemijska tehnika in podaja znanja, potrebna za lažje razumevanje vsebin, ki so zajete npr. pri predmetu Farmacevtska tehnika. Transferable/Key Skills and other attributes: The subject is connected to other subjects on the direction Chemical engineering and gives the knowledge which is necessary for understanding other subjects such as Pharmaceutical technology. Metode poučevanja in učenja: - predavanja - laboratorijske vaje Learning and teaching methods: - lectures - laboratory work Načini ocenjevanja: Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: - pisni izpit - ustni izpit - laboratorijske vaje Delež (v %) / Weight (in %) 60 30 10 32 Assessment: Student has to pass successfully the following obligations: - written examination - oral examination - laboratory work Reference nosilca / Lecturer’s references: KNEZ, Željko, ŠKERGET, Mojca, KNEZ HRNČIČ, Maša. Principles of supercritical fluid extraction and applications in the food, beverage and nutraceutical industries. V: RIZVI, Syed S. H. (ur.). Separation, extraction and concentration processes in the food, beverage and nutraceutical industries. Oxford [etc.]: Woodhead Publishing Limited, 2010, str. [3]-38. MARKOČIČ, Elena, ŠKERGET, Mojca, KNEZ, Željko. Polylactide and poly(lactide-co-glycolide) processed with supercritical CO2 for biomedical applications. V: FELTON, Gary P. (ur.). Biodegradable polymers : processing, degradation and applications. Hauppauge, N.Y.: Nova Science Publishers, 2011, str. [517]-543. KNEZ, Željko, FRITSCH, Markus, SCHULZE, Joachim, LÜTGE, Christoph. Process for the purification of carboxylic acids by subcritical or supercritical fluid chromatography : European patent application no. 2745905 A1, date of publication: 25. 06. 2014 Bulletin 2014/26; appl. no.: 12008534.5, date of filling: 21. 12. 2012. Munich: Europäisches Patentamt: = European Patent Office: = Office européen des brevets, 2014. KNEZ, Željko, ŠKERGET, Mojca, KNEZ HRNČIČ, Maša, ČUČEK, Denis. Particle formation using sub- and supercritical fluids. V: ANIKEEV, Vladimir (ur.), FAN, Maohong (ur.). Supercritical fluid technology for energy and environmental applications. Amsterdam: Elsevier, 2014, str. 31-67. 33 Energetski management procesov Predmet: Course title: UČNI NAČRT PREDMETA / COURSE SYLLABUS Energetski management procesov Energy Management of Processes Študijski program in stopnja Study programme and level Kemijska tehnika / 2. stopnja Chemical Engineering / 2nd level Študijska smer Study field Kemijska tehnika Chemical Engineering Vrsta predmeta / Course type: Letnik Academic year 2. Semester Semester zimski Autumn Obvezni / Obligatory Univerzitetna koda predmeta / University course code: Predavanja Lectures Seminar Seminar Sem. vaje Tutorials 30 Nosilec predmeta / Lecturer: Jeziki / Languages: Lab. vaje Laboratory work 30 Teren. vaje Field work Samost. delo Individ. work ECTS 120 6 Darko Goričanec Predavanja / Lecture: slovenski / Slovene Vaje / Tutorial: slovenski / Slovene Pogoji za vključitev v delo oz. za opravljanje študijskih obveznosti: Ni pogojev. Prerequisites: Vsebina: Energetske razmere v svetu Vrste energije, namen uporabe, razlogi za varčevanje Tehnični in praktični vidiki izkoriščanja virov energije Aktivni sistemi za izkoriščanje virov energije Racionalizacija uporabe energije v industriji Energijske pretvorbe v tehnoloških procesih Tehnologije za izkoriščanje odpadne toplote in vrednotenje investicij v smislu racionalizacije Značilni primeri energetskih ukrepov v kemijski procesni industrij Energetski pregledi Možni ukrepi za zmanjšanje porabe energije (predlogi izboljšav sistemov oskrbe z energijo) Analiza ukrepov za zmanjšanje porabe energije Content (Syllabus outline): Energy situation in the world Energy types, purpose, reasons for energy savings Technical and practical aspect of exploiting energy sources Active systems for exploitation of energy sources Rationalization of the use of energy in industry Energy transformations during technological processes Technology for exploiting waste heat and evaluating the rationality of investments Significant examples for measures taken in chemical process industry Energy revision Measures taken to reduce the consumption of energy (suggestions to improve the systems for supply of energy) None. 34 (potrebna investicijska sredstva, prihranki, ekološka presoja, doba vračila, lista ukrepov) Metode dinamičnega izračuna gospodarnosti energetskih postrojev Vaje: Študent samostojno reši več praktičnih primerov in izdela krajšo projektno nalogo. Analysis of measures to reduce consumption of energy (the investment assets needed, savings, ecological evaluation, list of measures) Methods of dynamic calculation of economic efficiency energy systems Exercises: Student individually solve the more practical examples and short process design formulation. Temeljni literatura in viri / Textbooks: Capehart, B. L., Turner, W. C., Kennedy, W. J., Guide to energy management, 6th Edition, 2008. Dodatna priporočena literatura: A. P. Rossiter, B. P. Jones, Energy Management and Efficiency for the Process Industries, AIChE, 2015. Turner W., Energy management handbook, Fairmont press, Liburn, 2001. Aldo V da Rosa, Fundamentals of renewable energy processes, academic Press, august 3, 2005. John Twidell, Renewable energy resources, Taylor&Francis. 2nd edition, December 16, 2005. Cilji in kompetence: Študent se seznani s praktičnimi možnostmi za boljšo energetsko izobrazbo (npr. varčevanje z energijo, večji izkoristki v transformacijah energije) in izkoriščanje obnovljivih virov. Razvoj strokovnih spretnosti – spretnosti pri skupinskem delu in reševanju problemov. Objectives and competences: The student will acquire practical knowledge regarding the energy sector, such as saving the energy, increasing the efficiency while transforming the energy and using the renewable energy sources. Development of professional skills – skills in team work and problem. Predvideni študijski rezultati: Znanje in razumevanje: Možnost ocene primerjave količinskih in kakovostnih vplivov ukrepov na rabo energije in na emisije Kaj je energetski pregled podjetja? Katere spremembe v energetski porabi so nujne? Razumevanje osnovnih principov o možnostih izkoriščanja obnovljivih virov energije Intended learning outcomes: Knowledge and Understanding: Learning how to evaluate and compare the quantitative and qualitative effects of measures taken for the se of energy and emissions What is power assessment of a factory? What changes in power use of an enterprise are mandated through an assessment? Understanding the fundamental principles of the possibility of exploiting renewable energy sources Prenesljive/ključne spretnosti in drugi atributi: Sposobnost prenosa teoretičnih spoznanj na manj teoretično okolje in njihova uporaba za določitev primernih energetskih virov in njihove uporabe Sposobnost spremljanja sprememb, ki nastaja pri izvajanju energetske zasnove in racionalne rabe energije Transferable/Key Skills and other attributes: Ability to transfer theoretical knowledge in less theoretical environment and use of this knowledge to determine energy sources and sensible use of energy sources Acquiring the knowledge to follow the changes arising when preparing the energy base and when using the energy rationally Metode poučevanja in učenja: predavanja obravnava študijskih primerov aktivno skupinsko delo Learning and teaching methods: lectures field work active team work 35 Načini ocenjevanja: Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: seminarska naloga teoretični del izpita računski del izpita Delež (v %) / Weight (in %) 20 30 50 Teoretični in računski del tvorita celoto in se preverjata hkrati. Assessment: Student has to pass successfully the following obligations: seminar theoretical part of the exam calculation part of the exam The theoretical and the calculus part of exam are performed simultaneously. Reference nosilca / Lecturer’s references: DOBERŠEK, Danijela, GORIČANEC, Darko. An experimentally evaluated magnetic device's efficiency for water-scale reduction on electric heaters. Energy, ISSN 0360-5442. [Print ed.], Available online 27 September 2014, str. 1-8. SORŠAK, Marko, ŽEGARAC LESKOVAR, Vesna, PREMROV, Miroslav, GORIČANEC, Darko, PŠUNDER, Igor. Economical optimization of energy-efficient timber buildings: Case study for single family timber house in Slovenia. Energy, ISSN 0360-5442. [Print ed.], Article in Press 2014, str. 1-9. GORIČANEC, Darko, POZEB, Viljem, TOMŠIČ, Ladislav, TROP, Peter. Exploitation of the waste-heat from hydro power plants. Energy, ISSN 0360-5442. [Print ed.], Available online 22 July 2014, str. 1-6, doi: 10.1016/j.energy.2014.06.106. [COBISS.SI-ID 17986326]. KULČAR, Bojan, GORIČANEC, Darko, KROPE, Jurij. Economy of replacing a refrigerant in a cooling system for preparing chilled water = Remplacement du frigorigene dans un systeme utilisé pour préparer de l'eau glacée : impact financier. International journal of refrigeration, ISSN 0140-7007. [Print ed.], Aug. 2010, vol. 33, iss. 5, str. 989-994. ŽLAK, Janez, AGREŽ, Marko, DOBERŠEK, Danijela, GORIČANEC, Darko, KROPE, Jurij. Rentability of rotary heat regenerator use in ventilating systems = Rentabilnost upotrebe regeneratora topline u ventilacijskom sustavu. Strojarstvo, ISSN 0562-1887, 2010, vol. 52, no. 6, str. 665-671. 36 Sinteza procesov Predmet: Course title: UČNI NAČRT PREDMETA / COURSE SYLLABUS Sinteza procesov Process Synthesis Študijski program in stopnja Study programme and level Kemijska tehnika / 2. stopnja Chemical Engineering / 2nd level Študijska smer Study field Kemijska tehnika Chemical Engineering Vrsta predmeta / Course type: Letnik Academic year 2. Semester Semester zimski autumn Obvezni / Obligatory Univerzitetna koda predmeta / University course code: Predavanja Lectures 30 Seminar Seminar Nosilec predmeta / Lecturer: Jeziki / Languages: Sem. vaje Tutorial Lab. vaje Labor work 30 Teren. vaje Field work Samost. delo Individ. work 120 ECTS 6 Zdravko Kravanja Predavanja / Lecture: slovenski / Slovene Vaje / Tutorial: slovenski / Slovene Pogoji za vključitev v delo oz. za opravljanje študijskih obveznosti: Osnovna znanja iz načrtovanja in optimiranja procesov Prerequisites: Vsebina: Osnovni koncepti algoritemskih metod: predstavitev problema z drevesno in mrežno predstavitvijo, alternativne formulacije za matematično programiranje, modeliranje logičnih pogojev in disjunkcij. Content (Syllabus outline): Basic concepts of algorithmic methods: Tree and network problem representations. Alternative mathematical programming formulations. Modeling of logical constraints and disjunctives. Sinteza destilacijskih zaporedij: linearni model kolon z ostro separacijo, mešano-celoštevilski model za destilacijska zaporedja, toplotno integrirana destilacijska zaporedja. Sinteza reakcijskih omrežij: koncept dosegljivega območja, sinteza reakcijskih omrežij s ciljano formulacijo, sinteza reakcijskega omrežja v celotni procesni shemi. Basic knowledge of process design and optimization Synthesis of distillation sequences: Linear model for sharp split columns. Mixed-integer linear model for distillation sequences. Heat integrated distillation sequences. Reactor network synthesis: Geometrical concept for attainable region. Synthesis of reactor networks with a targeting formulation. Reactor network synthesis in overall process scheme. Synthesis of overall process schemes: 37 Superstructure representation of: basic subsystems, overall process schemes. Process synthesizer MIPSN. Sinteza celotnih procesnih shem: definiranje superstrukture: - osnovnih podsistemov, - celotnih procesov, procesni sintetizer MIPSYN. Computer room: synthesis of process systems. Računalniške vaje iz sinteze procesnih sistemov. Temeljni literatura in viri / Textbooks: Biegler L.T., I.E.Grossmann and A.W.Westerberg, Systematic Methods of Chemical Process Design, Prentice Hall, New Jersey, 1999. A. Brooke, D. Kendrick, A. Meeraus, R. Raman, GAMS - A user Guide, Scientific Press, GAMS Development Corporation, 2015. http://www.gams.com/dd/docs/bigdocs/GAMSUsersGuide.pdf Cilji in kompetence: Cilj je podati podrobnejše znanje o sintezi procesov in procesnih podsistemov. Objectives and competences: The aim is to give knowledge of synthesis of process schemes and their subsystems in more details. Predvideni študijski rezultati: Znanje in razumevanje: Obvladovanje teorije in aplikacij matematičnega programiranja (optimiranja) pri sintezi kemijskih in biokemijskih procesov ter njihovih podsistemov. Intended learning outcomes: Knowledge and Understanding: Understand theory and have knowledge of some practical applications of mathematical programming in synthesizing (bio)chemical processes and their subsystems. Transferable/Key Skills and other attributes: To have an understanding of the impact of synthesis solutions on safe, environmentally benign and economically effective operation of chemical and biochemical processes. Prenesljive/ključne spretnosti in drugi atributi: Imeti razumevanje o vplivu sinteznih rešitev na varno, okolju prijazno in ekonomsko učinkovito delovanje kemijskih in biokemijskih procesov. Metode poučevanja in učenja: Predavanja, seminar in računalniške vaje. Samostojno delo študenta. Načini ocenjevanja: Izpit je opravljen, če sta pozitivno opravljeni naslednji obveznosti: seminarska naloga predstavitev seminarske naloge Learning and teaching methods: Lectures, seminar work, and computer practice. Self-learning. Delež (v %) / Weight (in %) Assessment: Student has to pass successfully the following obligations: Seminar work 70 30 Presentation of the seminar work Reference nosilca / Lecturer’s references: AHMETOVIĆ, Elvis, KRAVANJA, Zdravko. Simultaneous optimization of heat-integrated water networks involving process-to-process streams for heat integration. Applied thermal engineering, ISSN 1359-4311. [Print ed.], Jan. 2014, vol. 62, iss. 1, str. 302-217, doi: 10.1016/j.applthermaleng.2013.06.010. NEMET, Andreja, KLEMEŠ, Jiri, KRAVANJA, Zdravko. Designing a Total Site for an entire lifetime under fluctuating utility prices. Computers & chemical engineering, ISSN 0098-1354. [Print ed.], Available online 18 July 2014, vol. , str. 1-24, doi: 10.1016/j.compchemeng.2014.07.004. ČUČEK, Lidija, MARTÍN, Mariano, GROSSMANN, Ignacio E., KRAVANJA, Zdravko. Multi-period synthesis of optimally-integrated biomass and bioenergy supply network. Computers & chemical engineering, ISSN 0098-1354. [Print ed.], 4 Jul. 2014, vol. 66, str. 57-70, doi: 10.1016/j.compchemeng.2014.02.020. KRAVANJA, Zdravko, ČUČEK, Lidija. Multi-objective optimisation for generating sustainable solutions considering total effects on the environment. V: DUIĆ, Neven (ur.). Sustainable development of energy, water and environment systems, (Applied Energy, ISSN 0306-2619, Vol. 101, (2012)). Oxford: Elsevier, cop. 2012, vol. 101, str. 67-80, doi: 38 10.1016/j.apenergy.2012.04.025. ČUČEK, Lidija, KLEMEŠ, Jiri, KRAVANJA, Zdravko. A Review of Footprint analysis tools for monitoring impacts on sustainability. Journal of cleaner production, ISSN 0959-6526. [Print ed.], Oct. 2012, vol. 34, str. 9-20, doi: 10.1016/j.jclepro.2012.02.036. 39 Procesne surovine za bio in prehrambeno industrijo Predmet: Course title: UČNI NAČRT PREDMETA / COURSE SYLLABUS Procesne surovine za bio in prehrambeno industrijo Process Raw Materials for Bio and Food Industry Študijski program in stopnja Study programme and level Kemijska tehnika / 2. stopnja Chemical Engineering / 2nd level Študijska smer Study field Biokemijska tehnika Biochemical Engineering Vrsta predmeta / Course type: Letnik Academic year 2. Semester Semester zimski Autumn Obvezni / Obligatory Univerzitetna koda predmeta / University course code: Predavanja Lectures 30 Seminar Seminar Nosilec predmeta / Lecturer: Jeziki / Languages: Sem. vaje Tutorial Lab. vaje Labor work 30 Teren. vaje Field work Samost. delo Individ. work 120 ECTS 6 Zoran Novak Predavanja / Lecture: slovenski / Slovene Vaje / Tutorial: slovenski / Slovene Pogoji za vključitev v delo oz. za opravljanje študijskih obveznosti: Potrebno je znanje iz separacijske tehnike, mikrobiologije, biokemije, biokemijske tehnike, industrijske mikrobiologije in biotehnologije. Prerequisites: Vsebina: - Uvod - Prevzem in skladiščenje surovin. - Priprava surovin (čiščenje, sortiranje, luščenje). - Surovine v biotehnoloških procesih za proizvodnjo živil in krmil živalskega in rastlinskega izvora. - Surovine v fermentacijski industriji. - Biomasa - biološka surovina, proizvedena iz rastlin in živali. - Surovine za proizvodnjo biomase in njihova priprava (surovine v trdnem, tekočem in plinastem stanju). - Mikroorganizmi za proizvodnjo biomase. - Procesi in aparature. - Primeri. Content (Syllabus outline): - Introduction - Raw materials in food industries - Storage of raw materials. - Preparation of raw materials. - Raw materials of animal and vegetal source in biotechnological processes for production of food and feeding stuff. - Raw materials in fermentation industry. - Biomass from plant and animal origin. - Raw materials for biomass production and their preparation. - Microorganisms for biomass production. - Processes and apparatus. - Examples. Laboratorijske vaje iz področja kontrole surovin v bio industriji. Laboratory work on the case of raw material control in bio-industry. Knowledge of separation processes, microbiology, biochemistry, biochemical engineering, industrial microbiology and biotechnology is needed. 40 Temeljni literatura in viri / Textbooks: P. Fellows, Food Processing Technology: Principles and Practice, 3rd ed., CRC Press, USA, 2009. Dodatna priporočena literatura: S. Gad, Handbook of Pharmaceutical Biotechnology Pharmaceutical Development, Wiley-VCH, Weinheim, 2007. M. C. Flickinger, Upstream and Downstream Industrial Biotechnology, 3V Bundle, Wiley, ISBN: 978-1118-13125-1, 2014. M. C. Flickinger, Encyclopedia of Industrial Biotechnology, Bioprocess, Bioseparation, and Cell Technology , 7 Volume Set, Wiley, ISBN: 978-0-471-79930-6, 2010. Cilji in kompetence: Razumevanje tehnik priprave surovin v industrijske namene. Objectives and competences: Understanding of techniques for raw materials preparation in industrial use. Predvideni študijski rezultati: Znanje in razumevanje: Optimalna izbira surovin glede na zahteve nadaljne predelave oz. biosinteze ter ekonomike proizvodnje. Intended learning outcomes: Knowledge and Understanding: Optimal selection of raw materials, considering further application or biosynthesis and economic of the process. Prenesljive/ključne spretnosti in drugi atributi: Predmet se dopoljnjuje z ostalimi vsebinami na smeri Biokemijska tehnika. Transferable/Key Skills and other attributes: The subject is related to the other subjects on the study feild Biochemical engineering. Metode poučevanja in učenja: Predavanja v učilnici, ki je opremljena z avdiovizualnimi pripomočki. Individualna priprava seminarskih nalog s predstavitvijo in diskusijo. Laboratorijsko delo na izbranem primeru. Learning and teaching methods: Lectures in lecture room, equipped with audio-visual equipment Individual preparation of seminars and their presentation with discussion. Laboratory work on a selected case. Načini ocenjevanja: Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: - laboratorijske vaje (dnevnik, kolokvij) - pisni izpit - ustni izpit Delež (v %) / Weight (in %) 20 60 20 Assessment: Student has to pass successfully the following obligations: - laboratory work (report, colloquium) - written examination - oral examination Reference nosilca / Lecturer’s references: KNEZ, Željko, AIONICESEI, Elena, NOVAK, Zoran, KNEZ HRNČIČ, Maša. Processing polymeric biomaterials using supercritical CO[sub]2. Chemieingenieurtech., 2011, vol. 83, no. 9, str. 1371-1380. [COBISS.SI-ID 15347734] VERONOVSKI, Anja, NOVAK, Zoran, KNEZ, Željko. Synthesis and use of organic biodegradable aerogels as drug carriers. Journal of biomaterials science, Polymer edition, ISSN 0920-5063, 2012, vol. 23, no. 7, str. 873-886., doi: 10.1163/092050611X566126. [COBISS.SI-ID 15819286], VERONOVSKI, Anja, TKALEC, Gabrijela, KNEZ, Željko, NOVAK, Zoran. Characterisation of biodegradable pectin aerogels and their potential use as drug carriers. Carbohydrate polymers, ISSN 0144-8617. [Print ed.], 26 Nov. 2014, vol. 113, str. 272-278, doi: 10.1016/j.carbpol.2014.06.054. [COBISS.SI-ID 18000150] HE, Li, ZHANG, Xiaofei, XU, Honggao, XU, Chao, YUAN, Fang, KNEZ, Željko, NOVAK, Zoran, GAO, Yanxiang. Subcritical water extraction of phenolic compounds from pomegranate (Punica granatum L.) seed residues and investigation into their antioxidant activities with HPLC-ABTS assay. Food and bioproducts processing, ISSN 09603085, Apr. 2012, vol. 90, iss. 2, str. 215-223, doi: 10.1016/j.fbp.2011.03.003. [COBISS.SI-ID 14920470] 41 Sodobne procesne tehnike v živilstvu Predmet: Course title: UČNI NAČRT PREDMETA / COURSE SYLLABUS Sodobne procesne tehnike v živilstvu Modern Process Operations in Food Engineering Študijski program in stopnja Study programme and level Kemijska tehnika / 2. stopnja Chemical Engineering / 2nd level Študijska smer Study field Biokemijska tehnika Biochemical Engineering Vrsta predmeta / Course type: Letnik Academic year 2. Semester Semester zimski Autumn Obvezni / Obligatory Univerzitetna koda predmeta / University course code: Predavanja Lectures 30 Seminar Seminar Nosilec predmeta / Lecturer: Jeziki / Languages: Sem. vaje Tutorial Lab. vaje Labor work 30 Teren. vaje Field work Samost. delo Individ. work 120 ECTS 6 Mojca Škerget Predavanja / Lecture: slovenski/Slovene Vaje / Tutorial: slovenski/Slovene Pogoji za vključitev v delo oz. za opravljanje študijskih obveznosti: Osnovno znanje prenosnih pojavov (prenos toplote in snovi) in osnovnih procesnih operacij. Prerequisits: Vsebina: Reologija živilskih izdelkov:osnovni pojmi, reološka klasifikacija fluidov, reološki modeli, vpliv temperature in vpliv koncentracije na viskoznost. Termične lastnosti živilskih izdelkov: toplotna prevodnost, specifična toplotna kapaciteta, gostota, termična difuzivnost. Načrtovanje postopkov termičnega procesiranja živil – sterilizacija: hitrost termične inaktivacije, procesiranje konzerviranih produktov, aseptični postopek procesiranja tekočin. Načrtovanje postopkov konzerviranja živil s hlajenjem: zamrzovanje, temperatura zmrzišča, termične lastnosti zamrznjenih živil, čas zamrzovanja, načrtovanje zamrzovalnega sistema, hlajenje in hladilni sistemi. Sodobni tehnološki postopki v predelavi živil: priprava snovi, membranske operacije, Content (Syllabus outline): Rheology of food products: fundamentals, rheological classification of food products, rheological models, influence of temperature and concentration on viscosity. Thermal properties of food: thermal conductivity, specific heat, density, thermal diffusivity. Thermal processing of foods: thermal death rate, treatment of canned products, aseptic processing of liquid products. Food preservation by cooling: freezing, freezing temperature, thermal properties of frozen foods, freezing time, design of freezing systems, refrigeration and refrigeration systems. Emerging technologies for food processing: Preparation of material, membrane processes, pasterization and sterilization by high pressure processing, encapsulation technologies for active food ingredients and functional foods, Basic knowledge on transport phenomena (heat and mass transfer) and unit operations. 42 pasterizacija in sterilizacija z visokimi tlaki, enkapsulacija komponent in vgradnja v funkcionalna živila, pridobivanje praškastih produktov s superkritičnimi fluidi. vpliv procesiranja na kvaliteto prehrambenih izdelkov: kemijske spremembe pri procesiranju in načrtovanje končnih produktov. pakiranje izdelkov, permeabilnost, pokvarljivost in rok trajanja: namen, nivoji pakiranja in embalažni materiali, načini pakiranja, prepustnost embalažnih materialov za pline in paro. Proizvodne tehnologije izbranih skupin prehrambenih izdelkov. Laboratorijske vaje: - Reološke lastnosti živilskih izdelkov, - Enkapsulacija aktivnih komponent in testi stabilnosti. production of powderous products by supercritical fluid technologies. Effects of food processing on quality of foods: chemical changes during processing and design of products with tailor-made properties; Food packing, permeability and Shelf-Life: functions of packing, levels of packing and materials, types of packing, permeability for gasses and vapour. Procesing technology of selected food product groups. Laboratory work: Rheological properties of foods, Encapsulation of active compounds and stability tests. Temeljni literatura in viri / Textbooks: A. Ibarz, G.V. Barbosa-Cánovas, Unit Operations in Food Engineering, CRC Press, Boca Raton, 2003. Emerging technologies for food processing, Ed.: D.-W. Sun, Elsevier Ltd., 2005. Dodatna priporočena literatura: Food Processing Handbook, Ed.: J. G.Brennan, Wiley-VCH Verlag GmbH, Weinheim, 2006. Food processing Principles and Applications, Eds: J. S. Smith, Y. H. Hui, Blackvell Publishing, 2004 P. Fellows: Food Processing Technology: Principles and Practice, 2nd ed., Woodland Publishing; 2000. Cilji in kompetence: Seznaniti študente s sodobnimi tehnološkimi postopki in principi in novimi tehnologijami, ki se uporabljajo za proizvodnjo prehrambenih izdelkov in sodobnih produktov, ki so narejeni po meri potrošnika. Študent bo poznal uporabnost različnih metod za različne skupine izdelkov in vpliv procesiranja na kvaliteto izdelka. Znal bo načrtovati in optimirati posamezne procesne operacije. Poznal bo zahteve in ukrepe, ki so potrebni za zagotavljanje varnosti živil v proizvodnji in prometu. Objectives and competences: The objective is to introduce the student to the operations and principles in food processing, emerging technologies and production of products with tailor-made properties. The students should be able to evaluate different types of unit operations in connection with treatment of different types of foods and the effects of processing on quality of foods. They should be able to design and optimize specific process operations. They should know the measures and arrangements which are necessary to assure food safety in production process and in retail. Predvideni študijski rezultati: Znanje in razumevanje: sodobnih operacij in principov procesiranja prehrambenih izdelkov; vplivov procesiranja na kvaliteto izdelkov; načrtovanje produktov po meri potrošnika; načrtovanje in optimiranje posameznih procesnih operacij; zahtev in ukrepov, ki so potrebni za Intended learning outcomes: Knowledge and Understanding: operations and principles of food processing; effects of processing on quality of foods; design of products with tailor-made properties; design and optimization of process operations; measures and arrangements necessary to assure food safety in production process and in retail. 43 zagotavljanje varnosti živil v proizvodnji in prometu. Prenesljive/ključne spretnosti in drugi atributi: - znanja za inovativno delo v prehrambeni industriji - razvoj novih produktov Transferable/Key Skills and other attributes: - Achieving knowledge for inovative work in food industry - Development of new products Metode poučevanja in učenja: Predavanja Reševanje problemov Laboratorijske vaje Learning and teaching methods: Lectures Solving problems Laboratory work Načini ocenjevanja: Način (pisni izpit, ustno izpraševanje, naloge, projekt) Ustni izpit Pisni izpit Laboratorijske vaje Delež (v %) / Weight (in %) 40 30 30 Assessment: Type (examination, oral, coursework, project): Oral examination Written examination Labor work Reference nosilca / Lecturer’s references: RAVBER, Matej, KNEZ, Željko, ŠKERGET, Mojca. Simultaneous extraction of oil- and water-soluble phase from sunflower seeds with subcritical water. Food chemistry, ISSN 0308-8146. [Print ed.], Jan. 2015, vol. 166, str. 316323, doi: 10.1016/j.foodchem.2014.06.025. [COBISS.SI-ID 17908502], PAVLOVIČ, Irena, KNEZ, Željko, ŠKERGET, Mojca. Hydrothermal reactions of agricultural and food processing wastes in sub- and supercritical water : a review of fundamentals, mechanisms, and state of research. Journal of agricultural and food chemistry, ISSN 0021-8561, 2013, vol. 61, no. 34, str. 8003-8025, doi: 10.1021/jf401008a. [COBISS.SI-ID 17077526], KNEZ, Željko, ŠKERGET, Mojca, KNEZ HRNČIČ, Maša. Principles of supercritical fluid extraction and applications in the food, beverage and nutraceutical industries. V: RIZVI, Syed S. H. (ur.). Separation, extraction and concentration processes in the food, beverage and nutraceutical industries. Oxford [etc.]: Woodhead Publishing Limited, 2010, str. [3]-38. [COBISS.SI-ID 14789910] VATAI, Tünde, ŠKERGET, Mojca, KNEZ, Željko. Extraction of phenolic compounds from elder berry and different grape marc varieties using organic solvents and/or supercritical carbon dioxide. Journal of food process engineering, ISSN 0145-8876, 2009, vol. 90, iss. 2, str. 246-254. http://dx.doi.org/10.1016/j.jfoodeng.2008.06.028, doi: 10.1016/j.jfoodeng.2008.06.028. [COBISS.SI-ID 12483094], MANDŽUKA, Zoran, ŠKERGET, Mojca, KNEZ, Željko. High pressure micronization of tristearate. Journal of the American Oil Chemists' Society, ISSN 0003-021X, Feb. 2010, vol. 87, no. 2, str. 119-125, doi: 10.1007/s11746-0091482-4. [COBISS.SI-ID 13787670], ŠKERGET, Mojca. Separacija naravnih učinkovin in formulacija produktov: zaključno poročilo o rezultatih znanstvenoraziskovalnega sodelovanja. Maribor: Fakulteta za kemijo in kemijsko tehnologijo, 2012. [8] f. [COBISS.SI-ID 15903510] 44 Genomika v biomedicinski tehnologiji Predmet: Course title: UČNI NAČRT PREDMETA / COURSE SYLLABUS Genomika v biomedicinski tehnologiji Genomics in Biomedical Technology Študijski program in stopnja Study programme and level Kemijska tehnika / 2. stopnja Chemical Engineering / 2nd level Študijska smer Study field Biokemijska tehnika Biochemical Engineering Vrsta predmeta / Course type: Letnik Academic year 2. Semester Semester zimski Autumn Obvezni / Obligatory Univerzitetna koda predmeta / University course code: Predavanja Lectures 30 Seminar Seminar Nosilec predmeta / Lecturer: Jeziki / Languages: Sem. vaje Tutorial Lab. vaje Labor work 30 Teren. vaje Field work Samost. delo Individ. work 120 ECTS 6 Uroš Potočnik Predavanja / Lecture: slovenski / Slovene Vaje / Tutorial: slovenski / Slovene Pogoji za vključitev v delo oz. za opravljanje študijskih obveznosti: Pogojev ni. Prerequisites: Vsebina: Osnove toksikologije in farmakogenomike tehnologije v genomiki: nanotehnologija, mikromreže (biočipi), tehnologija za avtomatsko gensko tipizacije enonukleotidnih polimorfizmov v celotnem genomu (SNPov), sekvenciranje celotnih genomov, Maldi-TOF, 2-D elektroforeza genomika in odkrivanje novih zdravil genomika raka asociacijske študija za odkrivanje novih genov povezanih s kompleksnimi boleznimi (avtoimunske bolezni, rak, astma, sladkorna…) funkcijska genomika transkriptomika fiziološka genomika primerjalna (komparativna ) genomika mikrobna genomika proteomika bioinformatika genetski testi v diagnostiki bolezni Content (Syllabus outline): Basics toxicology and pharmacogenomics genomic technologies: nanotechnology, microarrays (Biochips), whole genome genotyping of Single nucleotide Polymorphisms (SNPs), Maldi-TOF, 2-D electrophoresis genomics in drug discovery cancer genomics disease association study in common complex diseases (autoimmune diseases, cancer, asthma, diabetes…) functional genomics transcriptomics physiological genomics comparative genomics genomics of microorganisms proteomics bioinformatics statistical genetics and disease association analysis Genetics in diagnosis None. 45 genska terapija etika v genomiki Hibridizacije nukleinskih kislin, mikromreže Pomnoževanje molekul DNA v pogojih in vitro (PCR), Sekvenciranje DNA Dvohibridni kvasni sistem za določanje interakcij protein-protein Spreminjanje genov - in vitro mutageneza, živalski modeli z izbitim genom-pomen v funkcijski genomiki in bolezenskih modelih Preprečevanje izražanja genov - protismiselna tehnologija, siRNA Kloniranje človeških genov, reproduktivno kloniranje sesalcev, terapevtsko kloniranje Transgene rastline in živali Genska tehnologija pri proizvodnji zdravil in diagnostičnih sredstev Zakonodaja in varnostni predpisi za delo z genetsko spremenjenimi organizmi Vloga rekombinantne DNA tehnologije v sodobni družba: etični, sociološki in ekonomski vidiki Laboratorijske vaje: Priprava genomskih in cDNA knjižnic Kloniranje: Gostiteljski organizmi, vektorji, strategije kloniranja v prokariontske in evkariontske orgnizme, transformacija in transfekcija, ekspresija rekombinantnih proteinov Preiskava DNA za tipizacijo tkiv in za osebno identifikacijo Gene therapy Ethics in genomics Hybridization of nucleic acids, DNA micro arrays Polymerase DNA reaction (PCR), DNA sequencing Yeast two-hybrid system for identification of protein-protein interaction Site directed mutagenesis, knock-out technology and animal models-the role in functional genomics and animal disease models Silencing gene expression: RNAi, antisense RNA technology Cloning human genes, reproductive cloning of mammalians, therapeutic cloning Transgenic plants and animals Gene technology in drug production and diagnostics Low regulations and safety precautions for research and applications of genetic modified organisms Recombinant DNA technology and society: ethic and social economic issues Laboratory work: preparation of genomic and cDNA libraries Cloning: Host organisms, DNA cloning vectors, cloning strategy in eukaryotes and prokaryotes, transformation and transfect ion, expression of recombinant proteins DNA fingerprinting in forensics Temeljni literatura in viri / Textbooks: Thompson & Thompson: Genetics in Medicine, W.B.Saunders Company., 7the ISBN 0-7216-0244-4 and 7th ed. ISBN: 9781416030805, 2007. Tom Strachan, Judith Goodship & Patrick Chinnery, Genetics and genomics in medicine, Garland Sc, ISBN 9780815344803, 2014. Dodatna priporočena literatura: Bernard R. Glick, Jack J. Pasternak: Principles and applications of recombinant DNA, 3rd edition, ASM Press, Washington, 2003. Philip Benfey: Genomics, Prentice Hall, Inc., New Jersey , 2005. Cilji in kompetence: Študenti bodo spoznali osnovne tehnike in uporabo rekombinantne DNA tehnologije v raziskavah in v praksi. Objectives and competences: Students will be provided with basic techniques and applications of recombinant DNA technology in research and industry. Predvideni študijski rezultati: Znanje in razumevanje: tehnike in principi kloniranja DNA in ostalih pristopov v rekombinanti DNA tehnologiji uporaba rekombinantne DNA tehnologije v raziskavah in praksi Prenesljive/ključne spretnosti in drugi atributi: Intended learning outcomes: Knowledge and Understanding: techiques and principles of DNA cloning and other recombinant DNA technology applications of recombinant DNA technology in research and industry Transferable/Key Skills and other attributes: 46 Metode poučevanja in učenja: Predavanja Seminarske vaje Laboratorijske vaje Načini ocenjevanja: Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: pisni izpit ustni izpit Learning and teaching methods: Lectures Tutorial Laboratory work Delež (v %) / Weight (in %) 60 40 Assessment: Student has to pass successfully the following obligations: writen examination oral examination Reference nosilca / Lecturer’s references: JOSTINS, Luke, MITROVIČ, Mitja, POTOČNIK, Uroš. Host-microbe interactions have shaped the genetic architecture of inflammatorybowel disease. Nature (Lond.), 2012, vol. 491, no. 7422, str. 119-124, doi: 10.1038/nature11582. [COBISS.SI-ID 512230968], LIU, Jimmy Z, MITROVIČ, Mitja, POTOČNIK, Uroš. Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis. Nat Genet, 2013, 79 str., ilustr. http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.2616.html, doi: 10.1038/ng.2616. [COBISS.SI-ID 512280376], RIVAS, Manuel A, MITROVIČ, Mitja, POTOČNIK, Uroš. Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease. Nat Genet, 2011, vol. 43, no. 11, str. 1066-1073, doi: 10.1038/ng.952. [COBISS.SI-ID 15421974], ALMOUZNI, Geneviève, GRGUREVIČ, Neža, MAJDIČ, Gregor, POTOČNIK, Uroš, ILAŠ, Janez, et al. Relationship between genome and epigenome - challenges and requirements for future research. BMC genomics, ISSN 14712164, 2014, vol. 15, no. 487, str. 1-7. http://www.biomedcentral.com/1471-2164/15/487, doi: 10.1186/14712164-15-487. [COBISS.SI-ID 512412216], REPNIK, Katja, POTOČNIK, Uroš. Haplotype in the IBD5 region is associated with refractory Crohn's disease in Slovenian patients and modulates expression of the SLC22A5 gene. J Gastroenterol, 2011, vol. 46, no. 9, str. 10811091, doi: 10.1007/s00535-011-0426-6. [COBISS.SI-ID 15110422]. 47 Okoljska biotehnologija Predmet: Course title: UČNI NAČRT PREDMETA / COURSE SYLLABUS Okoljska biotehnologija Environmental Biotechnology Študijski program in stopnja Study programme and level Letnik Academic year Študijska smer Study field Kemijska tehnika / 2. stopnja Chemical Engineering / 2nd level 2. Vrsta predmeta / Course type: Semester Semester zimski Autumn Izbirni / Elective Univerzitetna koda predmeta / University course code: Predavanja Lectures 15 Seminar Seminar Nosilec predmeta / Lecturer: Jeziki / Languages: Sem. vaje Tutorial Lab. vaje Labor work 15 Teren. vaje Field work Samost. delo Individ. work 150 ECTS 6 Maja Leitgeb Predavanja / Lecture: slovenski / Slovene Vaje / Tutorial: slovenski / Slovene Pogoji za vključitev v delo oz. za opravljanje študijskih obveznosti: Prerequisites: Potrebno je znanje iz mikrobiologije, biokemije, industrijske mikrobiologije in separacijske tehnike. Knowledge of microbiology, biochemistry, industrial microbiology and separation processes is needed. Vsebina: Odpadne vode (komunalne, industrijske, lastnosti). Čiščenje odpadnih vod z aerobnimi procesi (cilji in omejitve, vrste procesov). Čiščenje odplak z anaerobnimi procesi (biologija formiranja metana, vrste procesov, procesni pogoji). Biološko čiščenje odpadnega zraka in razgradnja trdnih odpadkov. Vzorčevanje, priprava vzorcev, ekstrakcija celic, detekcija funkcionalnih aktivnosti v vzorcih iz okolja. Bioremediacija. Kompostiranje. Bioinsekticidi. Content (Syllabus outline): Wastewater (communal sewage, industrial effluents, properties of the substrate wastewater). Purification of wastewater by aerobic processes (aims and limitations, purification processes). Purification of effluents by anaerobic processes (biology of formation of methane, technical processes, process conditions). Biological purification of waste air and degradation of solid wastes. Sampling, sample preparation, cell extraction, detection of functional activity in environmental samples. Bioremediation. Composting. Bioinsecticides. 48 Laboratorijske vaje iz področja detekcije funkcionalnih aktivnosti v vzorcih iz okolja. Laboratory work from the field of detection of functional activity in environmental samples. Temeljni literatura in viri / Textbooks: G. M. Evans, J. C. Furlang, Environmental Biotechnology: Theory and Applications, 2nd ed., Wiley Weinheim, 2010. R. H. Baltz, A. L. Demain, J. E. Davies, Manual of Industrial Microbiology and Biotechnology, 3 rd ed., ASM Press, Washington, D.C., 2010. Dodatna priporočena literatura: G. Lear, G. D. Lewis, Microbial Biofilms: Current Research and Applications, Caister Academic Press, New Zealand, 2012. Cilji in kompetence: Uporaba bioloških snovi (organizmov ali njihovih delov), skupaj s kemijskimi, fizikalnimi in inženirskimi procesi, za zaščito in obnovo okolja. Objectives and competences: Application of biological agents (organisms or their components), along with chemical, physical and engineering processes to protect and restore the environment. Predvideni študijski rezultati: Znanje in razumevanje: Poznavanje vloge »tehnične mikrobiologije« pri razvoju procesov čiščenja odpadnih vod in zraka ter tehnologij z uporabo bioloških sistemov za katalizo razpada ali transformacije raznih kemikalij v manj škodljive oblike. Intended learning outcomes: Knowledge and Understanding: Understanding of the role of »technical microbiology« in the development of waste water and air purification processes and technologies that use biological systems to catalyze the destruction or transformation of various chemicals to less harmful forms. Prenesljive/ključne spretnosti in drugi atributi: Predmet se dopoljnjuje z ostalimi vsebinami smeri Biokemijska tehnika. Transferable/Key Skills and other attributes: The subject is related to the other subjects on the study field Biochemical engineering. Metode poučevanja in učenja: Predavanja v učilnici, ki je opremljena z avdiovizualnimi pripomočki. Individualna priprava seminarskih nalog s predstavitvijo in diskusijo. Laboratorijsko delo na izbranem primeru. Learning and teaching methods: Lectures in a lecture room, equipped with audiovisual equipment Individual preparation of seminars and their presentation with discussion. Laboratory work on a selected case. Načini ocenjevanja: Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: - laboratorijske vaje - ustni izpit Delež (v %) / Weight (in %) 30 70 49 Assessment: Student has to pass successfully the following obligations: - laboratory work - oral examination Reference nosilca / Lecturer’s references: LEITGEB, Maja, ČOLNIK, Maja, PRIMOŽIČ, Mateja, ZALAR, Polona, GUNDE-CIMERMAN, Nina, KNEZ, Željko. Activity of cellulase and [alpha]-amylase from Hortaea werneckii after cell treatment with supercritical carbon dioxide. The Journal of supercritical fluids, ISSN 0896-8446. 2013, 78, 143-148, doi: 10.1016/j.supflu.2013.03.029. [COBISS.SIID 16864790] ČOLNIK, Maja, PRIMOŽIČ, Mateja, KNEZ, Željko, LEITGEB, Maja. Use of supercritical carbon dioxide for proteins and alcohol dehydrogenase release from yeast Saccharomyces cerevisiae. The Journal of supercritical fluids, ISSN 08968446. 2012, 65, 11-17, doi: 10.1016/j.supflu.2012.02.018. [COBISS.SI-ID 15901462] KAVČIČ, Sabina, KNEZ, Željko, LEITGEB, Maja. Antimicrobial activity of n-butyl lactate obtained via enzymatic esterification of lactic acid with n-butanol in supercritical trifluoromethane. The Journal of supercritical fluids, ISSN 0896-8446. 2014, 85, 143-150, doi: 10.1016/j.supflu.2013.11.003. [COBISS.SI-ID 17392406] THOREY, Paul, KNEZ, Željko, LEITGEB, Maja. Alcohol dehydrogenase in non-aqueous media using high-pressure technologies : reaction set-up and deactivation determination. Journal of chemical technology and biotechnology, ISSN 0268-2575. 2010, 85, 1011-1016. [COBISS.SI-ID 14291222] KNEZ, Željko, MARKOČIČ, Elena, LEITGEB, Maja, PRIMOŽIČ, Mateja, KNEZ HRNČIČ, Maša, ŠKERGET, Mojca. Industrial applications of supercritical fluids : a review. Energy, ISSN 0360-5442. 2014, 1-9, doi: 10.1016/j.energy.2014.07.044. [COBISS.SI-ID 18010134] 50 Priprava in čiščenje vod Predmet: Course title: UČNI NAČRT PREDMETA / COURSE SYLLABUS Priprava in čiščenje vod Water Conditioning and Treatment Študijski program in stopnja Study programme and level Kemijska tehnika / 2. stopnja Chemical Engineering / 2nd level Študijska smer Study field Kemijska tehnika Chemical Engineering Vrsta predmeta / Course type: Letnik Academic year 2. Semester Semester zimski Autumn Izbirni / Elective Univerzitetna koda predmeta / University course code: Predavanja Lectures 15 Seminar Seminar Nosilec predmeta / Lecturer: Jeziki / Languages: Sem. vaje Tutorial Lab. vaje Labor work 15 Teren. vaje Field work Samost. delo Individ. work 150 ECTS 6 Marjana Simonič Predavanja / Lecture: slovenski / Slovene Vaje / Tutorial: slovenski / Slovene Pogoji za vključitev v delo oz. za opravljanje študijskih obveznosti: Splošno znanje iz anorganske in analizne kemije Prerequisites: Vsebina: Kemijska sestava in lastnosti vod: - pitnih - odpadnih Evropska zakonodaja Glavni onesnaževalci vod: težke kovine, pesticidi, PCB, motilci endokrinega sistema, antibiotiki Mehansko in kemijsko čiščenje pitnih vod Čiščenje komunalne odpadne vode (primarno, sekundarno, terciarno čiščenje) Čiščenje industrijske odpadne vode Napredni postopki čiščenja z membranami in ozonom z različnimi kombinacijami (UV, H2O2, katalizatorji) Content (Syllabus outline): Chemical Water Characteristics - drinking water - wastewater European Legislation Main Water Pollutants: heavy metals, pesticides, PCB, endocrine disruptors, antibiotics Mechanical and Chemical drinking water treatment Municipal wastewater treatment (primary, secondary, tertiary treatment) Industrial wastewater treatment Advanced water treatment: membrane or using ozone in combination with UV irradiation, H2O2, catalysts Seminar work: Students independently solve problems in the field of the municipal or industrial wastewater treatment and discuss the solutions. Seminarska naloga: študentje samostojno obdelajo določen problem s področja čiščenja komunalnih in industrijskih odpadnih vod. General knowledge of Inorganic and Analytical Chemistry 51 Temeljni literatura in viri / Textbooks: Roš M., Simonič M., Šostar-Turk S., Priprava in čiščenje vod, Maribor: Fakulteta za strojništvo (Tiskarna tehniških fakultet), 2005. Dodatna priporočena literatura: Manahan S.E., Environmental Chemistry, 8th edition, CRC Press USA, 2005. Wastewater Engineering, Treatment and Reuse, 4th edition. Mc Graw Hill Co, 2003. Cilji in kompetence: Spoznati pomembnost priprave vod Spoznati fizikalno-kemijske tehnike priprave in čiščenja vod Osvojiti napredne tehnike čiščenja Sposobnost predlagati najprimernejšo tehnologijo čiščenja Sposobnost izboljšanja obstoječih tehnologij čiščenja vod Sposobnost preliminarnega načrtovanja naprav Objectives and competences: To acquaint with water conditioning Understanding the physico-chemical techniques of water conditioning and treatment To acquaint advanced techniques of water treatment Ability to propose the solution for the best water treatment method Understanding of how to improve the existing technologies for water treatment Ability to design the treatment plants Predvideni študijski rezultati: Razumevanje priprave vod Razumevanje fizikalno-kemijskih tehnik čiščenja vod Napredne tehnike čiščenja Sposobnost predlagati najprimernejšo tehnologijo čiščenja Sposobnost izboljšanja obstoječih tehnologij čiščenja vod Intended learning outcomes: Understanding of water treatment Understanding the physico-chemical techniques of water treatment Advanced techniques of water treatment Ability to propose the solution for the best water treatment method Ability to improve the existing technologies for water treatment Prenesljive/ključne spretnosti in drugi atributi: - osvojiti znanje za dobro delo v praksi - pripraviti pisna poročila in drugo dokumentacijo, - pisno in ustno komunicirati o problematiki. Transferable/Key Skills and other attributes: - achieving knowledge for good praxtice in industry, - prepare written reports - discuss the problem. Metode poučevanja in učenja: predavanja, seminarska naloga, ustni zagovor Learning and teaching methods: Lectures, Seminar work, Oral examinations Načini ocenjevanja: Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: ustni izpit seminarska naloga aktivno delo na predavanjih Delež (v %) / Weight (in %) 60 30 10 52 Assessment: Student has to pass successfully the following obligations: oral examination seminar work active work during lectures Reference nosilca / Lecturer’s references: TEPUŠ, Brigita, SIMONIČ, Marjana, PETRINIĆ, Irena. Comparison between nitrate and pesticide removal from ground water using adsorbents and NF and RO membranes. Journal of hazardous materials, ISSN 0304-3894. [Print ed.], 2009, vol. 170, iss. 2/3, str. 1210-1217. PETROVIČ, Aleksandra, SIMONIČ, Marjana. The efficiency of a membrane bioreactor in drinking water denitrification. Chemical industry & chemical engineering quarterly, ISSN 1451-9372, Online first 2014, vol. , no , str. 1-17. KRIŽAN, Janja, MURIĆ, Arnela, PETRINIĆ, Irena, SIMONIČ, Marjana. Recent developments in membrane treatment of spent cutting-oils: a review. Industrial & engineering chemistry research, ISSN 0888-5885. [Print ed.], 2013, vol. 52, no. 23, str. 7603-7616. KRIŽAN, Janja, PETRINIĆ, Irena, GORŠEK, Andreja, SIMONIČ, Marjana. Ultrafiltration of oil-in-water emulsion by using ceramic membrane : Taguchi experimental design approach. Central European Journal of Chemistry, ISSN 1895-1066, Feb. 2014, vol. 12, iss. 2, str. 242-249. 53 Nutracevtiki Predmet: Course title: UČNI NAČRT PREDMETA / COURSE SYLLABUS Nutracevtiki Nutraceuticals Študijski program in stopnja Study programme and level Študijska smer Study field Letnik Academic year Semester Semester 2. zimski Autumn Kemijska tehnika / 2. stopnja Chemical Engineering / 2nd level Vrsta predmeta / Course type: Izbirni / Elective Univerzitetna koda predmeta / University course code: Predavanja Lectures 15 Seminar Seminar Nosilec predmeta / Lecturer: Jeziki / Languages: Sem. vaje Tutorial Lab. vaje Labor work 15 Teren. vaje Field work Samost. delo Individ. work 150 ECTS 6 Mojca Škerget Predavanja / Lecture: slovenski / Slovene Vaje / Tutorial: slovenski / Slovene Pogoji za vključitev v delo oz. za opravljanje študijskih obveznosti: Pogojev ni. Prerequisites: Vsebina: prosti radikali in vloga antioksidantov v bioloških sistemih. identifikacija naravnih spojin z antioksidativnim, antimikotičnim ali farmakološkim učinkom: vitamini, karotenoidi, n-3 poli nenasičene maščobne kisline, fenolne spojine, lipojska kislina, terpenoidi, steroidi, alkaloidi,... naravni viri ter postopki izolacije in koncentriranja učinkovin: ekstrakcija, kromatografija,... vpliv učinkovine na zdravje ter na pojav boleznini in možnosti zdravljenja. metode določanja antioksidacijskega potenciala: in vitro testiranja (Rancimat test, peroksidno število, anizidinsko število, metoda s standardom TROLOX, BCB test (beta-carotene bleaching test), ORAC test (oxygen radical absorbance capacity), DPPH test (free radical Content (Syllabus outline): Free radicals and the role of antioxidants in biological systems; identification of substances with antioxidative, antimicotic or pharmacological activity (vitamins, carotenoids, n-3 polyunsaturated fatty acids, phenolic compounds, Lipoic acid, terpenoids, steroids, alkaloids,...); natural sources and isolation and concentration methods (extraction, chromatography,…); influence of substances on health and occurrence of sickness, disease prevention; methods for testing antioxidative activity: in vitro tests (Rancimat test,peroxide value, anisidine value, method with the standard TROLOX, BCB test (beta-carotene bleaching test), ORAC test (oxygen radical absorbance capacity), DPPH test (free radical scavenging capacity), test with the radical DMPD, determining the inhibition of human LDL,…), None. 54 scavening capacity), test s pomočjo radikala DMPD, določanje inhibicije oksidacije človeškega LDL, ....), biomarkerji oksidativnega stresa in vivo. Vaje: laboratorijsko delo na izbranem primeru, uporaba tehnik za izolacijo in koncentriranje nutracevtika in testiranja aktivnosti in vitro. oxidative stress biomarkers in vivo. Labor work: laboratory work on selected case, isolation and concentration of nutraceuticals, in vitro activity tests. Temeljni literatura in viri / Textbooks: Handbook of Nutraceuticals and Functional Foods, R. E. C. WILDMAN (Ed.), 2nd Ed., CRC Press, Taylor & Francis Group, Boca Raton 2007. K. Kramer, P.-P. Hoppe, L. Packer, eds., Nutraceuticals in Health and Disease Prevention. Marcel Dekker, Inc. New York, 2001. Dodatna priporočena literatura: D. Armstrong, ed., Oxidative Stress Biomarkers and Antioxidant Protocols. Humana Press Inc., New Jersey, 2002. J. Buttriss, M. Saltmarsh, eds., Functional foods II: claims and evidence, Cambridge: Royal Society of Chemistry, 2000. E. Cadenas, L. Packer, Handbook of Antioxidants, 2nd ed., Marcel Dekker, Inc. New York, 2002. Cilji in kompetence: Spoznati naravne produkte, ki pozitivno vplivajo na človeško zdravje (nutracevtiki), metode njihove izolacije, področja uporabe, kot tudi njihove vplive na zdravje in testne metode. Objectives and competences: To recognize natural products, which have positive influence on human health (nutraceuticals), the isolation methods, possible areas of application, as well as their influence on the health and test methods. Predvideni študijski rezultati: Znanje in razumevanje: Vrst, virov, metod pridobivanja, lastnosti in delovanje naravnih bioaktivnih komponent z antioksidativnim, antimikrobiološkim in farmakološkim učinkom za uporabo v prehrambni, kozmetični, predvsem pa v farmacevtski oziroma fitofarmacevtski industriji; In vitro in in vivo analiznih metod za testiranje antioksidacijskega potenciala Intended learning outcomes: Knowledge and Understanding: Types, sources, separation methods, properties and activity of natural bioactive compounds with antioxidative, antimicrobiological and pharmacological activity for the use in food, cosmetic and especially in pharmaceutical or phytopharmaceutical industry; In vitro and in vivo analytical methods for testing antioxidative potential. Prenesljive/ključne spretnosti in drugi atributi: znanja za inovativno delo v prehrambni, kozmetični, predvsem pa v farmacevtski oziroma fitofarmacevtski industriji. Transferable/Key Skills and other attributes: Achieving knowledge for inovative work in food, cosmetic and especially in pharmaceutical or phytopharmaceutical industry. Metode poučevanja in učenja: Predavanja, Laboratorijsko delo na izbranem primeru. Learning and teaching methods: Lectures, Laboratory work on selected case. 55 Načini ocenjevanja: Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: ustni izpit projektno poročilo Delež (v %) / Weight (in %) 50 50 Assessment: Student has to pass successfully the following obligations: Oral examination Project report Reference nosilca / Lecturer’s references: OMAN, Miha, ŠKERGET, Mojca, KNEZ, Željko. Application of supercritical fluid extraction for the separation of nutraceuticals and other phytochemicals from plant material. Macedonian journal of chemistry and chemical engineering, ISSN 1857-5552, 2013, vol. 32, no. 2, str. 183-226. [COBISS.SI-ID 17365014] ĐILAS, Sonja, KNEZ, Željko, ČETOJEVIĆ-SIMIN, Dragana, TUMBAS, Vesna, ŠKERGET, Mojca, ČANADOVIĆ-BRUNET, Jasna, CETKOVIC, Gordana. In vitro antioxidant and antiproliferative activity of three rosemary (Rosmarinus officinalis L.) extract formulations. International journal of food science & technology, ISSN 0950-5423. [Print ed.], 2012, vol. 47, iss. 10, str. 2052-2062, doi: 10.1111/j.1365-2621.2012.03069.x. [COBISS.SI-ID 16125206], RUŽIĆ, Iva, ŠKERGET, Mojca, KNEZ, Željko. Potential of phenolic antioxidants. Acta chimica slovenica, ISSN 13180207. [Tiskana izd.], 2010, vol 57, no. 2, str. 263-271. [COBISS.SI-ID 14214678]. RAVBER, Matej, KNEZ, Željko, ŠKERGET, Mojca. Simultaneous extraction of oil- and water-soluble phase from sunflower seeds with subcritical water. Food chemistry, 2015, vol. 166, str. 316-323. [COBISS.SI-ID 17908502]. ŠKERGET, Mojca. Separacija in koncentriranje naravnih učinkovin : znanstveno tehnološko sodelovanje z Republiko Madžarsko, 2008-2009 = Separation and concentration of active compounds : Slovenia-Hungary cooperation in science and technology, 2008-2009. Maribor: Fakulteta za kemijo in kemijsko tehnologijo; Budapest: Corvinus University of Budapest, Department of food Engineering, 2010. [5] f. [COBISS.SI-ID 15903254] ŠKERGET, Mojca, MAJHENIČ, Lucija, BEZJAK, Miran, KNEZ, Željko. Antioxidant, Radical Scavenging and Antimicrobial Activities of Red Onion (Allium cepa L) Skin and Edible Part Extracts. Chemical and biochemical engineering quarterly, ISSN 0352-9568, 2009, vol. 23, no. 4, str. 435-444, ilustr. [COBISS.SI-ID 13799190] 56 Management inoviranja Predmet: Course title: UČNI NAČRT PREDMETA / COURSE SYLLABUS Management inoviranja Innovation Management Študijski program in stopnja Study programme and level Študijska smer Study field Letnik Academic year Kemijska tehnika / 2. stopnja Chemical Engineering / 2nd level 2. Vrsta predmeta / Course type: Semester Semester zimski Autumn Izbirni / Elective Univerzitetna koda predmeta / University course code: Predavanja Lectures 15 Seminar Seminar Nosilec predmeta / Lecturer: Jeziki: Languages: Sem. vaje Tutorial Lab. vaje Labor work 15 Teren. vaje Field work Samost. delo Individ. work 150 ECTS 6 Dušan Klinar Predavanja / Lecture: slovensko / Slovene Vaje / Tutorial: slovensko / Slovene Pogoji za vključitev v delo oz. za opravljanje študijskih obveznosti: Pogojev ni. Prerequisites: Vsebina: - Osnove inoviranja in inovacij - Povezave sistema inoviranja in sistema kakovosti - Stategije in inoviranje - Potreba po raziskovanju in razvoju (RiR) - Management RiR (organiziranje, izvajanje, nadzor in metrika) - Storitve in RiR - Etična vprašanja RiR - Odnosi RiR z zunanjim in notranjim okoljem - Izhodišča, pomen, in umestitev razvoja novih produktov (RNP) - Pregled razvoja zamisli o RNP - Modeli in procesi RNP - Management RNP Content (Syllabus outline): - Fundamentals and theory of Innovation - Relationship among Innovation and quality systems - Strategy and Innnovation - Why Research and Development (R&D) - Management of R&D (organization, implementation, controling and metrics) - Service R&D - Ethical considerations of R&D - Integration R&D in environment and organization - Basics of the New Product Development (NPD) process - Idea generation for NPD - Concepts and processes of the NPD - NPD Management Seminarske vaje: - Obravnava primera dobre prakse - Analiza primera in primerjave None. Tutorial: - Cases of good practise 57 - Program RNP - Case analysis and bench marking - NPD project Temeljni literatura in viri / Textbooks: Borut Likar, O inovativnosti slovenske predelovalne in izbranih storitvenih dejavnosti, Univerza na Primorskem, Fakulteta za management Koper, 2014, izbrana poglavja. Peter Fatur, Borut Likar, Ustvarjalnost zaposlenih za inovativnost podjetja: sistemski vidiki managementa idej kot gradnika uspešne organizacije, Univerza na Primorskem, Fakulteta za management Koper, 2009, izbrana poglavja. Dodatna priporočena literatura: Ettlie, J. E., Managing Innovation, Butterworth-Heinemann, 2006. Ettlie, J. E., Managing Technological Innovation, John Wiley & Sons, 2000. Rainey, D. L., Sustainable Business Development Inventing the Future Through Strategy, Innovation, and Leadership, Cambridge University Press, 2010. Cooper, R.G., Winning at New Products: Creating Value Through Innovation, Basic Books, 2011. Cilji in kompetence: Spoznati vsebino in pomen: managementa inoviranja in inovacij inoviranja in strateškega planiranja v podjetju inoviranja in sistema kakovosti v podjetju vloge RiR v podjetju principov vodenja in upravljanja RiR izhodišč, pomena in umestitve RNP izvedbenega procesa RNP Objectives and competences: To acquaint the content and meaning: innovation management innovations and strategic planning innovations and quality management R&D in business unit management R&D NPD processes process of the implementation NPD Predvideni študijski rezultati: Znanje in razumevanje: - pomena in vsebine inoviranja, inovacijskih procesov v podjetju in nacionalni ekonomiji - vodenja in upravljanja RiR - pomena managementa RNP Prenesljive/ključne spretnosti in drugi atributi: - razumevanje inovacijske verige in pomena managementa pri svojem delu - zavedanje pomena RiR v podjetju - zavedanje pomena RNP Intended learning outcomes: Knowledge and Understanding: - of the meaning of innovation, principles and processes within the company and within national economy - management of the R&D - the importance of NPD management Transferable/Key Skills and other attributes: - to understand innovation chain and innovation management - to understand meaning of RiR in the company - to understand meaning of the NPD proces Metode poučevanja in učenja: - predavanja - multimedijske predstavitve - obravnave primerov - obravnava aktualnega stanja inoviranja v državi - delo na internetu - seminarske vaje - priprava elaborata Learning and teaching methods: - lectures - multimedia presentations - case studies - discussion about the actual national innovation system - online www search - seminar training - preparation of the expert's detail report Načini ocenjevanja: Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: - predstavitev projekta Delež (v %) / Weight (in %) 60 58 Assessment: Student has to pass successfully the following obligations: - project presentation - projektno delo - ustni izpit 20 20 - project work - oral examination Reference nosilca / Lecturer’s references: NAROBE, Miha, GOLOB, Janvit, KLINAR, Dušan, FRANCETIČ, Vojmir, LIKOZAR, Blaž. Co-gasification of biomass and plastics: pyrolysis kinetics studies, experiments on 100 kW dual fluidized bed pilot plant and development of thermodynamic equilibrium model and balances. Bioresource technology, ISSN 0960-8524. [Print ed.], Jun. 2014, vol. 162, str. 21-29. http://www.sciencedirect.com/science/article/pii/S096085241400426X, doi: 10.1016/j.biortech.2014.03.121. [COBISS.SI-ID 5457690] LAH, Branko, KLINAR, Dušan, LIKOZAR, Blaž. Modeling, optimization and scale-up of waste tire pyrolysis. V: 6th Dubrovnik Conference on Sustainable Development of Energy, Water and Environment Systems, September 25 October 29, 2011, Dubrovnik, Croatia. Conference proceedings. [S. l.: s. n.], 2011, str. [1-15], ilustr. [COBISS.SIID 4837146] KLINAR, Dušan, BRENCELJ, Albin. Metoda za ciklično vakumiranje v šaržnem reaktorju : patent št. SI 23545 A, datum objave 31. 05. 2012; patentna prijava št. P-201000369 z dne 09. 11. 2010. Ljubljana: Urad RS za intelektualno lastnino, 2012. [5] str. [COBISS.SI-ID 16117782] KLINAR, Dušan. Doseganje učinkovitosti rabe virov s kombiniranjem snovne in energetske izrabe = Resource efficiency by combination of material and energy recovery path. V: Strokovno posvetovanje 2014 Gospodarno in odgovorno!, Moravske Toplice, Hotel Ajda, 20. in 21. marec 2014. Ljubljana: Zveza ekoloških gibanj Slovenije, 2014, str. 115-121, ilustr. [COBISS.SI-ID 17909014] HARB, Darja, SELINŠEK, Zdenka, KLINAR, Dušan, PETEK, Janez. Okoljska ekonomika in podjetništvo : sestavina študijskega programa. [Ljubljana: CPI, 2011]. http://www.cpi.si/files/cpi/userfiles/Datoteke/kurikulum/Programoteka/PROGVIS/Bionika/Bionika_2011_P10_Bionska_ekonomika_in_podjetni%C5%A1tvo.doc [COBISS.SI-ID 356479] 59 Čistejša proizvodnja Predmet: Course title: UČNI NAČRT PREDMETA / COURSE SYLLABUS Čistejša proizvodnja Cleaner Production Študijski program in stopnja Study programme and level Kemijska tehnika / 2. stopnja Chemical Engineering / 2nd level Študijska smer Study field Kemijska tehnika Chemical Engineering Vrsta predmeta / Course type: Letnik Academic year 2. Semester Semester zimski Autumn Izbirni / Elective Univerzitetna koda predmeta / University course code: Predavanja Lectures 15 Seminar Seminar Nosilec predmeta / Lecturer: Jeziki / Languages: Sem. vaje Tutorial 15 Lab. vaje Labor work Teren. vaje Field work Samost. delo Individ. work 150 ECTS 6 Zorka Novak Pintarič Predavanja / Lecture: slovenski / Slovene Vaje / Tutorial: slovenski / Slovene Pogoji za vključitev v delo oz. za opravljanje študijskih obveznosti: Načrtovanje procesov Razvoj produktov in procesov Prerequisites: Vsebina: Zgodovinski razvoj od ‘end-of-pipe’ tehnologij do preprečevanja onesnaževanja. Hierarhija čistejše proizvodnje (preprečevanje v fazi načrtovanja, zmanjševanje na viru, obtakanje, obdelava, uničevanje, odlaganje). Izbor surovin, katalizatorjev, topil, reakcijskih poti. Osnovne operacije in čistejša proizvodnja (kemijski reaktorji, separacija, obtakanje, obratovanje, pogonski sistemi). Energetska in snovna integracija za čistejšo proizvodnjo. Metodologija za vključitev načel čistejše proizvodnje v načrtovanje in sintezo procesov. Okoljsko tveganje procesov (modeliranje izpustov v okolju, reakcije razgradnje v okolju, kvantitativna metrika). Content (Syllabus outline): The historical development from end-of-pipe to pollution prevention. Cleaner production hierarchy (prevention during the design, source reduction, recycling, treatment and disposal). Selection of feedstocks, catalysts, solvents, reaction pathways. Unit operations and cleaner production (chemical reactors, separation, recycling, process operation, utility systems) Energy and mass integration for cleaner production. Methodology for improving environmental performance during process design and synthesis. Environmental risk assessment (model approach for determining fate and transport of chemical releases into the environment, reaction loss processes, metrics for environmental risk evaluation). Seminarske vaje: načrtovanje trajnostnih procesov Seminar work: sustainable design of processes and Process Design Product and Process Development 60 in produktov s praktičnimi primeri (priprava na projekt, analiza stanja, iskanje idej za izboljšanje, razvoj konceptov, okoljski vplivi, akcijski načrt in ocenjevanje), priprava pisne seminarske naloge. products with case studies (preparation of an ecodesign project, assessment phase, generation of alternatives, developing concepts, environmental aspects, action plan and evaluation), preparation of written report. Temeljni literatura in viri / Textbooks: El-Halwagi M. M. Sustainable Design Through Process Integration (poglavja 1, 4, 5). Elsevier, Oxford, 2012. Klemeš J., Friedler F., Bulatov I., Varbanov P. Sustainability in the Process Industry, Integration and Optimization (poglavji 4, 10), McGraw Hill, 2011. Smith R., Chemical Process Design and Integration (poglavje 28), J. Wiley, 2005. Schefflan R., Teach Yourself the Basics of Aspen Plus (poglavji 11, 14), AIChE, Wiley, 2011. Dodatna priporočena literatura: Mulholland K. L. Identification of Cleaner Production Improvement Opportunities. John Wiley & Sons, New Jersey, 2006. Azapagić A. Perdan S., Clift R. Sustainable development in practice. John Wiley & Sons, Chichester, 2004. Allen D. T., Ahonnard D. R. Green Engineering – Environmentally Conscious Design of Chemical Processes. Prentice Hall, Upper Saddle River, 2002. Cilji in kompetence: Razumevanje kompleksnejših metodologij in metod čistejše proizvodnje v procesih, storitvah, razumevanje nastajanja vplivov na okolje v vseh fazah življenjskega kroga, razviti celovit pogled na okoljski vpliv proizvoda v vseh fazah življenjskega kroga proizvoda in načini znižanja teh vplivov na obstoječih ali proizvodih v načrtovalni fazi. Objectives and competences: Understanding complex cleaner production methodologies and techniques of the production processes and services. Understanding environmental impacts of the entire life cycle of products, knowing possibilities of the decreasing the environmental impacts of existing and new products during the design phase. Predvideni študijski rezultati: Znanje in razumevanje: Študent mora biti sposoben samostojno izvesti projekt čistejše proizvodnje v poljubnem proizvodnem procesu, ovrednotiti okoljske vplive skozi celotni življenjski krog, okoljsko primerjati in določiti kriterije odločanja med več istovrstnimi produkti ter poznati in razumeti osnove metodologije okoljskega načrtovanja proizvoda vključno z analizo in izboljšanjem poljubnega proizvoda. Intended learning outcomes: Knowledge and Understanding: A student should be able to implement CP project in production process, assess environmental aspects of the entire life cycle of a product and to define environmental criteria for the decision making between products. He/she has to understand basic methodology of eco-design and carry out the analysis and improvement options of a product. Prenesljive/ključne spretnosti in drugi atributi: Celostni pristop k okoljski analizi procesov. Uporaba tehnik in metodologij ČP, LCA in okoljskega načrtovanja. Metode poučevanja in učenja: Predavanja z diskusijo, izdelava posamičnega ali skupinskega seminarskega dela z uporabo ustrezne programske opreme. Transferable/Key Skills and other attributes: Integral approach to the process analysis. Application of the methodologies and techniques of CP, LCA and Eco-design. Learning and teaching methods: Lecture with discussion of the practical problems, carrying out the individual or team seminar work. 61 Načini ocenjevanja: Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: - ustni izpit - seminarska naloga - predstavitev seminarske naloge Delež (v %) / Weight (in %) 30 50 20 Assessment: Student has to pass successfully the following obligations: - oral examination - seminar work - presentation of seminar work Reference nosilca / Lecturer’s references: TOKOS, Hella, NOVAK-PINTARIČ, Zorka, YANG, Yongrong. Bi-objective optimization of a water network via benchmarking. Journal of cleaner production, ISSN 0959-6526. [Print ed.], 2013, vol. 39, str. 168-179, doi: 10.1016/j.jclepro.2012.07.051. [COBISS.SI-ID 16240918] KRAVANJA, Zdravko, NOVAK-PINTARIČ, Zorka, SIMONIČ, Marjana, ŠKOF, Gorazd. Optimizacija obstoječe in načrtovanje nove naprave za čiščenja odpadnih oljnih emulzij : zaključno poročilo projekta. Maribor: Fakulteta za kemijo in kemijsko tehnologijo, Laboratorij za procesno sistemsko tehniko in trajnostni razvoj, 2013. 53 str., ilustr. [COBISS.SI-ID 17120534] TOKOS, Hella, NOVAK-PINTARIČ, Zorka, KRAJNC, Damjan. An integrated sustainability performance assessment and benchmarking of breweries. Clean technologies and environmental policy, ISSN 1618-954X, 2012, vol. 14, no. 2, str. 173-193, doi: 10.1007/s10098-011-0390-0. [COBISS.SI-ID 15021334] KRAVANJA, Zdravko, ROPOTAR, Marcel, NOVAK-PINTARIČ, Zorka. Two-step multiobjective synthesis of sustainable chemical processes. Theoretical foundations of chemical engineering, ISSN 0040-5795, 2012, vol. 46, no. 6, str. 689698. [COBISS.SI-ID 16434710] TOKOS, Hella, NOVAK-PINTARIČ, Zorka. Development of a MINLP model for the optimization of a large industrial water system. Optimization and engineering, ISSN 1389-4420, 2012, vol. 13, iss. 4, str. 625-662, doi: 10.1007/s11081-011-9162-2. [COBISS.SI-ID 15125014] 62 Mehanika fluidov II Predmet: Course title: UČNI NAČRT PREDMETA / COURSE SYLLABUS Mehanika fluidov II Fluid Mechanics II Študijski program in stopnja Study programme and level Študijska smer Study field Letnik Academic year Semester Semester Kemijska tehnika / 2. stopnja Chemical Engineering / 2nd level Kemijska tehnika Chemical Engineering 2. zimski Autumn Vrsta predmeta / Course type: Izbirni / Elective Univerzitetna koda predmeta / University course code: Predavanja Lectures Seminar Seminar 15 Lab. vaje Laboratory work Teren. vaje Field work 15 Nosilec predmeta / Lecturer: Jeziki / Languages: Sem. vaje Tutorial Samost. delo Individ. work ECTS 150 6 Darko Goričanec Predavanja / Lectures: slovenski / Slovene Vaje / Tutorial: slovenski / Slovene Pogoji za vključitev v delo oz. za opravljanje študijskih obveznosti: Osnovno znanje matematike. Prerequisits: Vsebina: Ne–Newtonove tekočine: razvrstitev, napetosti in viskoznost v ceveh Pretok skozi nanešene plasti: karakteristike plasti, izgube trenja, mehanska energijska bilanca Pretok v fluidiziranih plasteh Padajoči delci v fluidu Dvofazni tok Vodni in plinski pretočni sistemi: faktor istočastnosti, načrtovanje in dimenzioniranje, optimizacija, namestitev črpalk, tranzientni pojavi, izbira pretočnih poti. Seminarske vaje: Vaje se navezujejo na tematiko predmeta Content (Syllabus outline): Basic knowledge of mathematics. Non – Newton fluids: classification of fluids, shear stress and viscosity, flow in pipes Flow through packed beds: characterization of a packed bed, frictional loss, and mechanical energy balance. Flow in fluidized beds: the fluidized state, frictional loss and pumping requirement to fluidize a bed of solids, minimum fluidizing velocity Solid particles falling through fluids Two phase flow Water and gas flow systems: factor of simultaneity, design and dimensioning, optimisation, location of pumps, transient phenomena Tutorials will be based on chosen topic regarding the theme of the subject. Študent samostojno reši deset praktičnih primerov 63 Students individually solve ten practical examples. Temeljni literatura in viri / Readings: Frank M. White, Fluid Mechanics 6th edition, McGraw Hill, 2008. Dodatna priporočena literatura: James O. Wilkes: Fluid Mechanics for Chemical Engineers with Microfluids and CFD 2nd Edition, Prentice Hall, 2005. Octave Levenspiel, Tracer Technology: Modeling the Flow of Fluids, Springer; 2012. Pijush K. Kundu, Ira M. Cohen: Fluid Mechanics, Second Edition, Academic Press, 2001. Joel H. Ferziger, Milovan Peric: Computational Methods for Fluid Dynamics, Springer Verlag, 2001. Cilji in kompetence: Osnovne informacije o vrstah, pomenu in lastnostih vodnih in plinskih omrežij Osvojiti postopke modeliranja sistemov Objectives and competences: Basic information about the types, meaning and the characteristics of water and gas networks Predvideni študijski rezultati: Znanje in razumevanje: • Slušatelji se seznanijo z nekaterimi temeljnimi in praktičnimi znanji vezanimi na energetska omrežja. Intended learning outcomes: Knowledge and Understanding: • Of fundamental and practical knowledge regarding energy networks Transferable/Key Skills and other attributes: • Using the theory to solve practical problems Prenesljive/ključne spretnosti in drugi atributi: • Prenos teorije na reševanje praktičnih primerov Metode poučevanja in učenja: Predavanja: študent spozna teoretične vsebine predmeta. Learning and teaching methods: Lectures: the student gets acquainted with theoretical content of the subject. Seminarske vaje: študent utrdi teoretično znanje in spozna aplikativne možnosti reševanja primerov iz prakse, študent izdela krajšo študijo oziroma projekt, ki se navezuje na tematiko predmeta. Seminar: the student upgrades the theoretical knowledge with practical experience, conducting a short study or project regarding the thematic of the subject. Načini ocenjevanja: Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: • seminarska naloga • računski del izpita • teoretični del izpita Delež (v %) / Weight (in %) 30 40 30 Teoretični in računski del tvorita celoto in se preverjata hkrati. Assessment: Student has to pass successfully the following obligations: • individual paper • calculation part of the exam • theoretical part of the exam The theoretical and the calculus part of exam are performed simultaneously. 64 Reference nosilca / Lecturer’s references: JOTANOVIĆ, Milovan, MIŠČEVIĆ, Mirko, KULČAR, Bojan, GORIČANEC, Darko. Optimal proportion of refrigerants in single- stage high-temperature heat pump. International journal of systems applications, engineering & development, ISSN 2074-1308. [Online ed.], 2012, vol. 6, iss. 6, str. 365-375. http://www.naun.org/multimedia/UPress/saed/16-565.pdf. [COBISS.SI-ID 16535830] KROPE, Jurij, GORIČANEC, Darko, DOBERŠEK, Danijela. Optimizacija lokacije deponije, tehnologije transporta in doziranja komunalne biomase v sušilnik premoga TET : končno poročilo. Maribor: Fakulteta za kemijo in kemijsko tehnologijo, 2012. 90 f., ilustr. [COBISS.SI-ID 16563222 DOBERŠEK, Danijela, GORIČANEC, Darko, KROPE, Jurij. Dryers for sewage sludge dehydration. International journal of energy and environment, 2012, vol. 6, iss. 6, str. 588-596. http://www.naun.org/multimedia/NAUN/energyenvironment/16-691.pdf. [COBISS.SI-ID 16535062] ZORKO, Jerneja, GORIČANEC, Darko, KROPE, Jurij. Process of oxygen transfer and power requirements in activated sludge wastewater treatment plant. Research Journal of Chemistry and Environment, ISSN 0972-0626, 2011, vol. 15, no. 2, str. 1-3, graf. prikazi. [COBISS.SI-ID 15168534], DOBERŠEK, Danijela, GORIČANEC, Darko, KROPE, Jurij. Use of drag-reducing additives in district heating systems. V: The fifth International Conference on Thermal Engineering: Theory and Applications [also] ICTEA, May 10-14, 2010, Marrakesh, Morocco. Proceeding. [S. l.]: ICTEA, cop. 2010, str. 231-234. [COBISS.SI-ID 14194454] 65 Termodinamika zmesi Predmet: Course title: UČNI NAČRT PREDMETA / COURSE SYLLABUS Termodinamika zmesi Solution Thermodynamics Študijski program in stopnja Study programme and level Študijska smer Study field Letnik Academic year Semester Semester Kemijska tehnika / 2. stopnja Chemical Engineering / 2nd level Kemijska tehnika Chemical Engineering 2. zimski Autumn Vrsta predmeta / Course type: Izbirni / Elective Univerzitetna koda predmeta / University course code: Predavanja Lectures 15 Seminar Seminar Nosilec predmeta / Lecturer: Jeziki / Languages: Sem. vaje Tutorial Lab. vaje Labor work 15 Teren. vaje Field work Samost. delo Individ. work 150 ECTS 6 Mojca Škerget Predavanja / Lecture: slovenski / Slovene Vaje / Tutorial: slovenski / Slovene Pogoji za vključitev v delo oz. za opravljanje študijskih obveznosti: Prerequisites: Osnovno znanje termodinamike Basic knowledge of thermodynamics Vsebina: Predavanja Termodinamika faznih ravnotežij: osnovne enačbe in parcialni odvodi, lastnosti čistih snovi in realnih zmesi in metode določanja, enačbe stanja, fugativnost in fugativnostni koeficient, aktivnost in aktivnostni koeficient. Termodinamski opis zmesi: Parcialne molarne količine, presežne količine, fugativnost, aktivnost in aktivnostni koeficient. Večfazni sistemi: ravnotežje in stabilnost, fazni prehodi. Fazni diagrami ter termodinamski in empirični modeli za opis ravnotežij v sistemih plintekoče, tekoče-tekoče, trdno-tekoče in sistemih pri visokih tlakih. Content (Syllabus outline): Lectures Classical thermodynamics of phase equilibria: basic equations and partial derivatives, properties of pure substances and real mixtures and methods for determination, equations of state, fugacity and activity. The thermodynamic description of mixtures: partial molar properties, excess properties, fugacity, activity and activity coefficient. Multiphase systems: Equilibrium and stability, phase transitions. Phase diagrams, thermodynamic and empirical models for description of equilibria in systems Gas-liquid, Liquid-liquid, Solid-liquid, and systems at high pressure. Računalniške vaje: Izračun faznih ravnotežij z uporabo programskih orodij (npr. Aspen Plus,…): Computational work: Calculation of phase equilibria using software (e.g Aspen Plus,…): 66 - Izračun ravnotežij v sistemih plin-tekoče, Topnost plinov v tekočinah, Topnost trdnih snovi v tekočinah, Ravnotežja v sistemih pri visokih tlakih. - Calculation of gas-liquid equilibria, Solubility of gasses in liquids, Solubility of solids in liquids, High pressure equilibria, Temeljni literatura in viri / Textbooks: J. V. Sengers, R. F. Kayser, C. J. Peters and H. J. White, Jr., Equations of State for Fluids and Fluid Mixtures, Elsevier Science B. V., 2000. J. M.Prausnitz, R. N.Lichtenthaler, E. G. de Azevedo, Molecular thermodynamics of Fluid-Phase Equilibria, 3rd ed., Prentice Hall, New Jersey, 1998. Dodatna priporočena literatura: Stanley T. Sander, Chemical, Biochemical, and Engineering Thermodynymics, John Wiley&Sons, 2006. High-Pressure Fluid Phase Equilibria, Volume 2: Phenomenology and Computation (Supercritical Fluid Science and Technology), Eds.: U. K Deiters, Thomas Kraska, Elsevier; 1 edition, 2012. Cilji in kompetence: Uporaba termodinamike v mešanicah, s poudarkom na neidealnih mešanicah. Splošne metode, enačbe stanja in drugi termodinamski modeli, potrebni za kvantitativno obravnavanje mešanic in večkomponentnih zmesi. Objectives and competences: Application of thermodynamics to mixtures (solutions), with emphasis on non-ideal mixtures. Generalized methods, equations of state and other thermodynamic models, needed for quantitative treatment of mixtures and multicomponent mixtures. Predvideni študijski rezultati: Znanje in razumevanje: Po zaključku tega predmeta bo študent sposoben razumeti zakone termodinamike na višjem nivoju, predvsem za mešanice, večsnovne sisteme in večkomponentne raztopine; uporabiti enačbe stanja za večsnovne sisteme; obvladati termodinamske izračune za takšne sisteme. Intended learning outcomes: Knowledge and Understanding: On completion of this course the student will be able to understand laws of thermodynamics on a higher level, above all for mixtures, multicomponent mixtures and solutions; use equations of state for multicomponent systems; govern in a great extend thermodynamic calculations for such systems Transferable/Key Skills and other attributes: Communication skills, preferable the capability of collecting needed information's for thermodynamic calculations in mixtures. Solution of more sophisticated thermodynamic problems. Prenesljive/ključne spretnosti in drugi atributi: Spretnost komuniciranja, predvsem sposobnost zbiranja potrebnih informacij za termodinamske izračune v zmeseh. Reševanje bolj zapletenih termodinamskih problemov. Metode poučevanja in učenja: predavanja računalniške vaje Načini ocenjevanja: Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: Ocenjevanje predmeta Projektno delo (računalniške vaje) Ustni izpit Learning and teaching methods: Lectures Computer work Delež (v %) / Weight (in %) Assessment: Student has to pass successfully the following obligations: 50 50 67 Assessment of the subject Project (computational work) Defense of the project and oral exam Reference nosilca / Lecturer’s references: ŠKERGET, Mojca, ČUČEK, Denis, KNEZ, Željko. Phase equilibria of the propylene glycol/CO2 and propylene glycol/ethanol/CO2 systems. The Journal of supercritical fluids, ISSN 0896-8446. [Print ed.], Nov. 2014, vol. 95, str. 129-136, [COBISS.SI-ID 18135574]. PERKO, Tina, KNEZ, Željko, ŠKERGET, Mojca. Phase equilibria of glycerol tristearate and glycerol trioleate in carbon dioxide and sulfur hexafluoride. Journal of chemical and engineering data, ISSN 0021-9568, 2012, vol. 57, no. 12, str. 3604-3610, [COBISS.SI-ID 16419350]. ŠKERGET, Mojca, MANDŽUKA, Zoran, MARKOČIČ, Elena, KNEZ, Željko, JEŠE, Robi, ZNOJ, Bogdan, VENTURINI, Peter. Solubility and diffusivity of CO2 in carboxylated polyesters. The Journal of supercritical fluids, ISSN 0896-8446. [Print ed.], Jan. 2010, vol. 51, iss. 3, str. 306-311 [COBISS.SI-ID 13799446]. ŠKERGET, Mojca. Phase equilibrium in supercritical fluids : invited lecture presented at the International scientific colloquium Center of applied spectroscopy, 29 - 30 September, 2011, UM FKKT, Maribor. 2011. [COBISS.SI-ID 15456534]. KNEZ, Željko, ŠKERGET, Mojca, KNEZ HRNČIČ, Maša. Principles of supercritical fluid extraction and applications in the food, beverage and nutraceutical industries. V: RIZVI, Syed S. H. (ur.). Separation, extraction and concentration processes in the food, beverage and nutraceutical industries. Oxford [etc.]: Woodhead Publishing Limited, 2010, str. [3]-38. [COBISS.SI-ID 14789910]. PERKO, Tina, GUMZEJ, Jerneja, KNEZ, Željko, ŠKERGET, Mojca. Phase equilibria of flax seed oil - dense gases. V: 2nd Conference on Applied Biocatalysis and 7th Meeting of Students and University Professors from Maribor and Zagreb, November 7th and 8th 2011, Maribor, Slovenia. LEITGEB, Maja (ur.), PRIMOŽIČ, Mateja (ur.). 2nd Conference on "Applied Biocatalysis" and 7th Meeting of Students and University Professors from Maribor and Zagreb, November 7th and 8th 2011, Maribor, Slovenia. Maribor: Faculty of Chemistry and Chemical Engineering; Zagreb: Faculty of Chemical Engineering and Technology, 2011, 4 str. [COBISS.SI-ID 15534358]. 68 Upravljanje z okoljem Predmet: Course title: UČNI NAČRT PREDMETA / COURSE SYLLABUS Upravljanje z okoljem Environmental Management Študijski program in stopnja Study programme and level Kemijska tehnika / 2. stopnja Chemical Engineering / 2nd level Študijska smer Study field Kemijska tehnika Chemical Engineering Vrsta predmeta / Course type: Letnik Academic year 2. Semester Semester zimski Autumn Izbirni / Elective Univerzitetna koda predmeta / University course code: Predavanja Lectures 15 Seminar Seminar Nosilec predmeta / Lecturer: Jeziki / Languages: Sem. vaje Tutorial 15 Lab. vaje Labor work Teren. vaje Field work Samost. delo Individ. work 150 ECTS 6 Damjan Krajnc Predavanja / Lecture: slovenski / Slovene Vaje / Tutorial: slovenski / Slovene Pogoji za vključitev v delo oz. za opravljanje študijskih obveznosti: Ni pogojev. Prerequisites: Vsebina: Predavanja: Okoljski vplivi tehnoloških sistemov Evropska zakonodaja in mednarodni standardi Koncept in razvoj upravljanja z okoljem Metode okoljskega in ekološkega pregleda Teorija in praksa upravljanja z okoljem Sistemi ravnanja z okoljem Družbena odgovornost Merjenje trajnostnega razvoja Vseživljenjsko vrednotenje stroškov, okoljska presoja Večkriterijsko odločanje Content (Syllabus outline): Lectures: Environmental impacts of technological systems Environmental law, regulations and organizations Concept and Development of Environmental Management Methods of Environmental and Ecological Auditing Theory and Practice of environmental management Environmental Management Systems Corporate Social Responsibility Measuring Sustainable Development Life cycle costing, environmental impact assessment Multi-criteria decision making Seminar work: Will be based on chosen topic: environmental laws and regulations, implementation of environmental management systems in chosen companies from different industrial sectors, review of sustainability reports of companies, examples of multi-criteria decision making, environmental impact of production processes, role of selected fields of technological Seminarske vaje: Osnovane na izbrani temi: okoljska zakonodaja in predpisi, vzpostavitev sistemov upravljanja z okoljem v izbranih podjetjih iz različnih sektorjev, pregled poročil o trajnostnem razvoju podjetij, primeri večkriterijskega odločanja pri upravljanju z okoljem, okoljskih vplivi proizvodnih procesov, None. 69 vloga in vpliv izbranih področij tehnološkega razvoja na globalni trajnostni razvoj. development in global sustainable development. Temeljni literatura in viri / Textbooks: Krajnc D. Upravljanje z okoljem (zbrano gradivo), 2009, Univerza v Mariboru, Fakulteta za kemijo in kemijsko tehnologijo, http://www.fkkt.um.si/egradiva/fajli/upravljanje_z_okoljem.pdf. Dodatna priporočena literatura: Weiß P., Bentlage J., Environmental Management Systems and Certification, The Baltic University Press, 2006. Mulder K. Sustainable Development for Engineers – A Handbook and Resource Guide. Greenleaf Publishing Ltd, Sheffield UK, 2006. Cilji in kompetence: Razumevanje okoljskih vidikov in predpisov, razvoja okoljskih strategij, poročanja o okoljskem in trajnostnem delovanju, sistemov upravljanja z okoljem, okoljskega računovodstva in pregledov, večkriterijskega odločanja pri upravljanju z okoljem Objectives and competences: Understanding of environmental issues and regulations, development of environmental strategies, environmental and sustainability performance reporting, environmental management systems, environmental accounting and auditing, multi-criteria decision making. Predvideni študijski rezultati: Intended learning outcomes: nowledge and Understanding: Znanje in razumevanje: Po opravljenem predmetu bo študent sposoben Completing the course the student will be able to prepoznati in razumeti pomembnost upravljanja z recognize and understand the importance of okoljem za stanje podjetja glede okoljskih izzivov in environmental management for the situation of the konkurenčnosti. Študent bo sposoben uporabljati company regarding environmental challenges and metode okoljskih pregledov v podjetju in bo competitiveness. The student should be able to use seznanjen s teorijo in postopki vpeljevanja sistemov methods of environmental and ecological auditing upravljanja z okoljem v podjetju. Sposoben bo and be acquired with the theory and implementation razviti okoljske strategije, uporabljati okoljske in procedure for environmental management systems trajnostne kazalce, izvajati okoljsko merjenje in in companies. The student will be able to use preglede ter vključevati večkriterijsko odločanje v environmental and sustainability performance sistem upravljanja z okoljem. Pridobil bo znanje o indicators, environmental accounting and auditing konceptih, teorijah, metodah in orodjih pri and implement multi-criteria decision making in the environmental management. The student will industrijskem upravljanju z okoljem. acquire the knowledge of the concepts, theories, methods and tools of industrial environmental Prenesljive/ključne spretnosti in drugi atributi: management. Po opravljenem predmetu bo študent pridobil naslednje spretnosti: Transferable/Key Skills and other attributes: predlagati pristope k uvajanju upravljanja z On the completion of the course the student will okoljem v podjetju, acquire the following skills: uporabljati metode okoljskega in ekološkega propose approaches for environmental pregleda, management implementation in company, načrtovati in voditi projekte, uporabljati metode use methods of environmental and ecological večkriterijskega odločanja, auditing, uporabljati informacijske tehnologije. plan and manage projects, use methods of multicriteria decision making, use information technologies. 70 Metode poučevanja in učenja: Predavanja, vaje, samostojni študij problema, izdelava posamične ali skupinske seminarske naloge. Načini ocenjevanja: Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: pisni izpit seminarska naloga predstavitev seminarske naloge Learning and teaching methods: Lectures, exercises, independent problem study, carrying out the individual or team seminar work. Delež (v %) / Weight (in %) 50 40 10 Assessment: Student has to pass successfully the following obligations: written examination seminar work seminar work presentation Reference nosilca / Lecturer’s references: TOKOS, Hella, NOVAK-PINTARIČ, Zorka, KRAJNC, Damjan. An integrated sustainability performance assessment and benchmarking of breweries. Clean technologies and environmental policy, 2012, vol. 14, no. 2, str. 173-193. CZEKAJ, Marta, KRAJNC, Damjan. Sustainability assessment regarding the regional development of Sucha Beskidzka County, Poland. Polish journal of environmental studies, ISSN 1230-1485, 2011, vol. 20, no. 4A, str. 50-56. KOLETNIK, Damijan, LUKMAN, Rebeka, KRAJNC, Damjan. Environmental management of waste based on road construction materials. Aplinkos tyrimai, inžinerija ir vadyba, ISSN 1392-1649, 2012, vol. 59, no. 1, str. 42-46. 71 Eko-dizajn in ocena življenjskega cikla Predmet: Course title: UČNI NAČRT PREDMETA / COURSE SYLLABUS Eko-dizajn in ocena življenjskega cikla Eco-design and life cycle assessment Študijski program in stopnja Study programme and level Kemijska tehnika / 2. stopnja Chemical Engineering / 2nd level Študijska smer Study field Kemijska tehnika Chemical Engineering Vrsta predmeta / Course type: Letnik Academic year 2. Semester Semester zimski Autumn Izbirni / Elective Univerzitetna koda predmeta / University course code: Predavanja Lectures 15 Seminar Seminar Nosilec predmeta / Lecturer: Jeziki / Languages: Sem. vaje Tutorial 15 Lab. vaje Labor work Teren. vaje Field work Samost. delo Individ. work 150 ECTS 6 Damjan Krajnc Predavanja / Lecture: slovenski / Slovene Vaje / Tutorial: slovenski / Slovene Pogoji za vključitev v delo oz. za opravljanje študijskih obveznosti: Ni pogojev Prerequisites: Vsebina: Uvod v industrijsko ekološko načrtovanje: definicija in vloga v kemijski in procesnih industrijah, Snovni tokovi in eko-načrtovanje (vplivi na okolje in dileme, razpoložljivost in izčrpanost surovinskih virov), Strategije in koncepti eko-načrtovanja razvoj novega koncepta, raba materialov in vsebnost kemikalij, zmanjšanje snovnih tokov in porabe energije, načrtovanje za proizvodnjo, distribucijo, uporabo, odstranitev, podaljševanje življenjske dobe), Določitev ciljev in področja (ozadje analize, zahteve glede modeliranja, načrtovanje študije LCA), Inventarizacija (priprava diagrama poteka, zbiranje podatkov, postopek izračuna, alokacija), Analiza življenjskega cikla (okoljski vplivi, različne faze LCIA, metode karakterizacije) Content (Syllabus outline): - Introduction to Industrial Eco-Design: definition and role in chemical and process industries, - Resources flow and eco-design (environmental impact and dilemma of resource flows, resource availability and depletion), - Strategies and concepts of eco-design new concept development, materials application and chemical content, reducing material flows, reduction of energy consumption, design for production, distribution, use, end-of-life, product lifetime extension), - Goal and scope definition (context of the study, modelling requirements, planning of an LCA study), - Inventory analysis (construction of a flowchart, data collection, calculation procedure, allocation), - Life cycle impact assessment (what is an environmental impact, different phases of life cycle impact assessment, characterisation None 72 Razlaga in prikaz rezultatov (kvantitativni rezultati, testiranje robustnosti rezultatov), Kritični pregled LCA, Upravljanje podatkov LCA (programski paketi, baze podatkov, dokumentiranje LCA), methods), - Interpretation and presentation of results (quantitative results, testing the robustness of the results), - Critical review of LCA, - LCA data management (software packages, databases, documentation of LCA) - Green marketing, procurement and ecolabelling; - Product-oriented environmental policies. Zeleno oglaševanje, nabavljanje in okoljsko označevanje, Okoljska politika do proizvodov. Seminarske vaje: študent bo z metodologijo, orodji in programsko opremo obdelal določen problem iz področja ekodizajna in metode ocenjevanja življenjskega cikla. Seminar work: Student will independently solve problem in the field of eco-design and life cycle assessment using methodology, tools and software. Temeljni literatura in viri / Textbooks: Krajnc D. 2014. Eko-dizajn - Okoljsko načrtovanje, razvoj in analiziranje proizvodov in procesov. Univerza v Mariboru, Fakulteta za kemijo in kemijsko tehnologijo. Dodatna priporočena literatura: Zbiciński I., Stavenuiter J., Kozlowska B., van de Coevering H.P.M. 2006. Product Design and Life Cycle Assessment. The Baltic University Press. Bauman H., Tillman A.M. 2004. The Hitch Hiker's Guide to LCA. Studentlitteratur AB. European Commission - Joint Research Centre - Institute for Environment and Sustainability: International Reference Life Cycle Data System (ILCD) Handbook - General guide for Life Cycle Assessment - Detailed guidance. First edition March 2010. EUR 24708 EN. Luxembourg. Publications Office of the European Union; 2010. 73 Cilji in kompetence: Objectives and competences: Razumevanje metodologije okoljskega načrtovanja, poznavanje metod ocenjevanja vplivov na okolje v celotnem življenjskem ciklu proizvoda, metod načrtovanja posameznih faz življenjskega cikla, poznavanje in uporaba ustrezne programske opreme za okoljsko načrtovanje proizvodov. Understanding the eco (re)design methodologies and tools, understanding environmental impact assessment methods, be able to design life cycle phases of products, and use the eco design and LCA software. Predvideni študijski rezultati: Znanje in razumevanje: Študent mora biti sposoben izvesti analizo življenjskega cikla proizvoda, z obstoječimi orodji in programsko opremo ovrednotiti vplive na okolje v vseh fazah življenjskega cikla, obvladati tehnike izboljšanja obstoječih in načrtovanja novih proizvodov ter procesov, ki bodo imeli ekonomsko in okoljsko sprejemljive vplive na okolje in stroške. Intended learning outcomes: Knowledge and Understanding: Student should be able to perform the LCA of a product, with the help of existing tools and software to carry out environmental impact assessment of all product life cycle phases, be able to develop new concepts of products (existing and/or new ones) and processes with environmentally and economically acceptable impacts on the environment and costs Prenesljive/ključne spretnosti in drugi atributi: Celostni pristop k načrtovanju proizvodov in/ali storitev. Poznavanje metodologij okoljskega načrtovanja proizvodov in storitev. Uporaba osnovnih metod okoljskega izboljšanja obstoječih in načrtovanja novih procesov. Transferable/Key Skills and other attributes: Integral approach to the eco (re)design of products and services. Knowledge of the methodologies to be used in eco (re)design. Application of the basic methods and environmental improvements of the existing and new processes. Metode poučevanja in učenja: Predavanja, vaje, samostojni študij problema, izdelava posamične ali skupinske seminarske naloge. Learning and teaching methods: Lectures, exercises, independent problem study, carrying out the individual or team seminar work. Načini ocenjevanja: Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: - pisni - seminarska naloga - predstavitev seminarske naloge Delež (v %) / Weight (in %) 50 40 10 Assessment: Student has to pass successfully the following obligations: - written examination - seminar work - seminar work presentation Reference nosilca / Lecturer’s references: KRAJNC, Damjan. Okoljski vplivi različnih nagrobnih sveč in metoda LCA. Embalaža, okolje, logistika, ISSN 18554849, nov. 2010, št. 54. KRAJNC, Damjan. Vzpostavljanje ekoindustrijskih sistemov z načeli industrijske simbioze = The establishment of eco-industrial systems including the principles of industrial symbiosis. V: VOLFAND, Jože (ur.), ČERNUTA, Uroš. Odpadki v Sloveniji = Waste in Slovenia, (Zbirka Zelena Slovenija). Celje: Fit media, 2010. RADONJIČ, Gregor, PISNIK, Aleksandra, KRAJNC, Damjan. Product ecodesign in companies with ISO 14001 certified environmental management system. Environmental engineering and management journal, ISSN 1582-9596. Jan. 2015, vol. 14, no. 1, str. 176-181. TOKOS, Hella, NOVAK-PINTARIČ, Zorka, KRAJNC, Damjan. An integrated sustainability performance assessment and benchmarking of breweries. Clean technologies and environmental policy, 2012, vol. 14, no. 2, str. 173-193. ZHOU, Li, TOKOS, Hella, KRAJNC, Damjan, YANG, Yongrong. Sustainability performance evaluation in industry by composite sustainability index. Clean technologies and environmental policy, Oct. 2012, vol. 14, iss. 5, str. 789-803. 74 Surovine in proizvodnja premazov Predmet: Course title: UČNI NAČRT PREDMETA / COURSE SYLLABUS Surovine in proizvodnja premazov Raw Materials and Manufacture of Coatings Študijski program in stopnja Study programme and level Kemijska tehnika / 2. stopnja Chemical Engineering / 2nd level Študijska smer Study field Kemijska tehnika Chemical Engineering Vrsta predmeta / Course type: Letnik Academic year 2. Semester Semester zimski Autumn Izbirni / Elective Univerzitetna koda predmeta / University course code: Predavanja Lectures 15 Seminar Seminar Nosilec predmeta / Lecturer: Jeziki / Languages: Sem. vaje Tutorial 15 Lab. vaje Labor work Teren. vaje Field work Samost. delo Individ. work 150 ECTS 6 Mojca Škerget Predavanja / Lecture: slovenski / Slovene Vaje / Tutorial: slovenski / Slovene Pogoji za vključitev v delo oz. za opravljanje študijskih obveznosti: Osnovno znanje organske kemije z dodiplomskega študija. Prerequisites: Vsebina: kaj so premazi: definicije, sestava. veziva: naravna, modificirana naravna, sintetična. topila: klasifikacija in definicije, karakterizacija topil, lastnosti, topila v premaznih materialih. pigmenti in polnila: definicije in klasifikacija, fizikalne, beli pigmenti, črni pigmenti, anorganski barvni pigmenti, organski barvni pigmenti, sijajni pigmenti, funkcionalni pigmenti, polnila, barve. aditivi: definicije in klasifikacija, površinsko aktivni aditivi, reološki aditivi, stabilizatorji svetlobe, biocidi, močljivci in dispergirna sredstva, katalizatorji in sušilna sredstva. zakonodaja. barve in premazni sistemi, formulacija, tvorba filma (sušenje, zamreženje): sestava barv, osnovni parametri formuliranja, lastnosti filma. Content (Syllabus outline): What are coatings: definitions, composition. Film formers: Natural, Modified natural, Synthetic. Solvents: Classification and definitions, Characterisation of solvents, Properties, Solvents in coating materials. Pigments and fillers: Definitions and classification, pigment physic, White pigments, Black pigments, Inorganic coloured pigments, Organic coloured pigments, Lustre pigments, Functional pigments, Fillers, Dyes. Additives: Definitions and classification, Interface-active additives, Rheological additives, Light stabilizers, Biocides, Wetting and dispersing agents, Catalysts and driers, Flatting agents. Legislative Framework. Paint systems, formulation, film-forming (drying and curing, crosslinking): Basic knowledge of organic chemistry from undergraduate study. 75 barve na osnovi topil, barve na vodni osnovi, radikalsko zamrežljivi premazni materiali, praškasti premazi, anorganski premazni materiali. tvorba filma, sušenje in zamreženje. proizvodnja barv in premazov: procesne stopnje v proizvodnji premazov, naprave, formuliranje obdelovalne osnove, mešanje in raztapljanje, dispergiranje, drobljenje in gnetenje, filtracija, dispergiranje efektnih pigmentov, šaržni testi Specifične lastosti proizvodnje vodnih lakov. Proizvodnja praškastih premazov. Vaje: primeri premaznih sistemov, študij njihovih fizikalno kemijskih lastnosti ter vpliva na lastnosti premaza in možne napake, formulacije, sušenja in zamreženja premazov. Composition of paints, Basic formulating parameters film properties. Solvent-based paints, Waterborne paints, Radically-curing coating materials, Coating powders, Inorganic coating materials. Film-forming, drying, curing (crosslinking). Manufacture of paints and coatings: Process stages in the manufacture of coatings, Configuration of equipment, Formulating the mill base, Mixing and dissolving, Dispersion, Grinding and kneading, Filtration, Dispersing effect pigments, Batch tests. Special features of the production of waterborne enamels. Manufacture of coating powders. Tutorial: Case study of coating types, their physical and chemical properties and influence on coating properties and common failure modes, formulation and film-forming (drying and curing, crosslinking). Temeljni literatura in viri / Textbooks: Goldschmidt, H. J. Streitberger: BASF-Handbuch Lackiertechnik, Vincentz, Hannover, 2002. B. Müller, U. Poth: Coatings formulation, Hannover: Vincentz, 2006. Dodatna priporočena literatura: K. Hunger (Ed.): Industrial Dyes, Chemistry, Properties, Applcations, Wiley-VCH, Weinheim, 2003. H. Kittel, J. Spille (Hrsg.): Lehrbuch der Lacke und Beschichtungen, Bd. 5.; Hirzel, Stuttgart, 2003. T. Brock, M. Groteklaes, P. Mischke: European Coatings Handbook, Curt R. Vincentz Verlag, Hannover 2000. Cilji in kompetence: Cilj tega predmeta je osvojiti znanja o vrstah premaznih sistemov in njihovih surovinah ter o formuliranju, lastnostih ter procesnih stopnjah. Objectives and competences: The objective of this course is to achieve knowledge of the coating systems, raw materials for coatings, formulation, properties, and process stages. Predvideni študijski rezultati: Znanje in razumevanje: Poznavanje surovin za premaze in njihove lastnosti ter vpliv na lostnosti premaza; Poznavanje zakonodaje; Osnovne sestave in formuliranja premaznih sistemov, tipov premaznih materialov in njihovih lastnosti, tehnologij sušenja in zamreženja, mešanje in dispergiranje v proizvodnji barv. Intended learning outcomes: Knowledge and Understanding: Knowledge of raw materials for coatings, properties of specific compounds and the influence on the coating properties; Legislation; Basics of composition and formulations of paints, types of coating materials and their properties, technology of drying and curing, mixing and grinding (dispersing). Transferable/Key Skills and other attributes: Achieving basic knowledge for the work in the industry of paints and coatings Prenesljive/ključne spretnosti in drugi atributi: osnovna predznanja za delo v industriji barv in lakov 76 Metode poučevanja in učenja: Predavanja, seminarske vaje, strokovna ekskurzija v industrijo. Seminarska naloga: študent izdela krajšo študijo oz. projekt, ki se navezuje na tematiko predmeta. Načini ocenjevanja: Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: pisni izpit seminarska naloga Learning and teaching methods: Lectures, tutorial, visit to the industry. Individual project work: conducting a short study (project) regarding the thematic of the subject. Delež (v %) / Weight (in %) 60 40 Assessment: Student has to pass successfully the following obligations: written examination Seminar work report Reference nosilca / Lecturer’s references: ŠKERGET, Mojca, ČUČEK, Denis, KNEZ, Željko. Phase equilibria of the propylene glycol/CO2 and propylene glycol/ethanol/CO2 systems. The Journal of supercritical fluids, ISSN 0896-8446. [Print ed.], Nov. 2014, vol. 95, str. 129-136, doi: 10.1016/j.supflu.2014.08.019. [COBISS.SI-ID 18135574] ČUČEK, Denis, PERKO, Tina, ILIĆ, Ljiljana, ZNOJ, Bogdan, VENTURINI, Peter, KNEZ, Željko, ŠKERGET, Mojca. Phase equlibiria[!] and diffusivity of dense gases in various polyethylenes. The Journal of supercritical fluids, ISSN 08968446. [Print ed.], June 2013, vol. 78, str. 54-62, doi: 10.1016/j.supflu.2013.03.020. [COBISS.SI-ID 16830998], ŠKERGET, Mojca, MANDŽUKA, Zoran, MARKOČIČ, Elena, KNEZ, Željko, JEŠE, Robi, ZNOJ, Bogdan, VENTURINI, Peter. Solubility and diffusivity of CO2 in carboxylated polyesters. The Journal of supercritical fluids, ISSN 0896-8446. [Print ed.], Jan. 2010, vol. 51, iss. 3, str. 306-311, doi: 10.1016/j.supflu.2009.10.013. [COBISS.SI-ID 13799446] KNEZ, Željko, ŠKERGET, Mojca, KNEZ HRNČIČ, Maša, ČUČEK, Denis. Particle formation using sub- and supercritical fluids. V: ANIKEEV, Vladimir (ur.), FAN, Maohong (ur.). Supercritical fluid technology for energy and environmental applications. Amsterdam: Elsevier, 2014, str. 31-67, doi: 10.1016/B978-0-444-62696-7.00002-2. [COBISS.SI-ID 17592854] ŠKERGET, Mojca. Formuliranje prašnih lakov z visokotlačnim postopkom : zaključno poročilo o rezultatih raziskovalnega projekta. Maribor: Fakulteta za kemijo in kemijsko tehnologijo, 2011. loč. pag. [COBISS.SI-ID 14953238] 77 Aplikacija, lastnosti in testiranje premazov Predmet: Course title: UČNI NAČRT PREDMETA / COURSE SYLLABUS Aplikacija, lastnosti in testiranje premazov Application, Properties and Testing of Coatings Študijski program in stopnja Study programme and level Kemijska tehnika / 2. stopnja Chemical Engineering / 2nd level Študijska smer Study field Kemijska tehnika Chemical Engineering Vrsta predmeta / Course type: Letnik Academic year 2. Semester Semester zimski Autumn Izbirni / Elective Univerzitetna koda predmeta / University course code: Predavanja Lectures 15 Seminar Seminar Nosilec predmeta / Lecturer: Jeziki / Languages: Sem. vaje Tutorial Lab. vaje Labor work 7,5 Teren. vaje Field work 7,5 Samost. delo Individ. work 150 ECTS 6 Mojca Škerget Predavanja / Lecture: slovenski / Slovene Vaje / Tutorial: slovenski / Slovene Pogoji za vključitev v delo oz. za opravljanje študijskih obveznosti: Osnovno znanje organske in analizne kemije z dodiplomskega študija. Prerequisites: Vsebina: substrati in predobdelava: kovinski substrati, substrati iz umetnih mas, substrati iz lesa, mineralni substrati. aplikacija in sušenje: metode uporabe in pogoji, ročni nanos, nanos s polivanjem, nanos z valji, potopno in poplavno barvanje in sorodne tehnike, razpršilno barvanje (metode z in brez elektrostatičnega naboja), praškasti premazi, razpršilne komore, sušilne naprave. primeri procesov barvanja (avtomobilska industrija, umetne mase, lesna industrija in ostali industrijski procesi). okolju prijazne barve in premazi (premazi s povišano vsebnostjo trdne snovi, vodni Content (Syllabus outline): Substrates and pretreatment: Metal substrates, Plastic substrates, Wood substrates, Mineral substrates. Application and drying: Methods of application and criteria for use, Manual application by brushing, rolling, trowelling, wiping, Curtain coating, Roller coating, Dipping, flow coating and related applications, Electrodeposition coating, Spray application (methods without and with electrostatic charging), Powder coating, Spray booths, Drying installations. Examples of coatings processes (automotive, car refinishing, plastic coating, other industrial processes, wood coating). Basic knowledge of organic and analytical chemistry from undergraduate study. 78 premazi, suspenzije, praškasti premazi, z radiacijo zamrežljive barve in laki, ostali premazni sistemi). reologija in reometrija: osnove reologije, meritve pretočnih lastosti, viskoelastičnost. značilnosti tekočih in trdnih produktov. analitske vrednosti za trdne produkte. testiranje tekočih barv in premazov: optične lastnosti, emisija, tvorba filma, tečenje in zamreženje, obstojnost. specifični testi za praškaste premaze. lastnosti premazov po aplikaciji: merjenje debeline filma, optične lastnosti filma, barva in kolorimetrija, Mehanske lastnosti filma, svetlobna obstojnost in vodoodpornost. obstojnost premazov in premaznih sistemov. Vaje: uporaba standardnih analiznih metod za testiranje premaznih sistemov in premazov: testiranje mehanskih lastnosti, reoloških lastnosti, kemijske obstojnosti, obstojnosti na zunanje vplive. ekskurzija v industrijo. Environment Compatible Paints and Coatings (High Solids, Waterborne Paints, Slurry, Powder Coatings, Radiation Curable Paints and Coatings, Other Coating Systems). Rheology and rheometry: Rheological principles, Measuring flow behaviour, Viscoelasticity. Characteristics of solvents and liquid products: Analytical values for solids. Testing of liquid paints and coatings: Optical properties, Emissions, Film-forming, flow and crosslinking, Ring circuit stability. Specific tests for coating powders. Features of coatings after application: Film thickness measurement, Optical film properties, colour and colorimetry, Mechanical film properties, Light stability and weather resistance. Durability of coatings and coating systems. Labor work: Application of standard analytical methods for testing of coating systems and coatings: testing of mechanical properties, rhheological properties, chemical resistance, weathering resistance. Visit to the industry. Temeljni literatura in viri / Textbooks: P. A. Schweitzer, Paint and Coatings: Applications and Corrosion Resistance, Taylor & Francis Group Boca Raton, 2006. D. G. Weldon, Failure Analysis of Paints and Coatings, John Wiley & Sons Inc., 2001. Dodatna priporočena literatura: R. Dietrich, Paint Analysis, Vincentz Network, Hannover, 2009. T. Brock, M. Groteklaes, P. Mischke: European Coatings Handbook, Curt R. Vincentz Verlag, Hannover 2000. [ISBN: 3-87870-559-X]. Goldschmidt, A; Streitberger: H.-J., BASF-Handbuch Lackiertechnik, Vincentz: Hannover, 2002. Cilji in kompetence: Osvojiti znanja o optimalnih tehnikah nanosa in sušenja za različne premazne sisteme ter znanja o lastnostih premaznih sistemov, možnih napakah in analiznih metodah. Objectives and competences: Achieving knowledge about optimal application and drying techniques of different coating systems and properties of coating systems, possible failures and analytical methods. Predvideni študijski rezultati: Znanje in razumevanje: Poznavanje različnih tehnik nanosa tekočih in praškastih premazov. Sposobnost izbire najboljše tehnike nanosa za dan primer kot tudi najboljše tehnike sušenja oz zamreženja z vidika kvalitete, ekonomike in ekologije. Poznavanje lastnosti premaznih sistemov. Intended learning outcomes: Knowledge and Understanding: Variety of applications of fluid and powderous coating materials; Selecting best method for a given challenge as well as the best drying resp. curing way depending on quality, economical and ecological view points; Of properties of coating systems; 79 Poznavanje merilnih tehnik in analiznih metod za testiranje premazov. Of analytical methods and measuring technics for testing coatings. Prenesljive/ključne spretnosti in drugi atributi: osnovna predznanja za delo v industriji barv in lakov oz. na področjih njihove uporabe. Transferable/Key Skills and other attributes: Achieving basic knowledge for the work in the industry of paints and coatings and areas of their application. Metode poučevanja in učenja: predavanja strokovna ekskurzija v industrijo laboratorijske vaje Learning and teaching methods: Lectures Visit to the industry Laboratory work Načini ocenjevanja: Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: laboratorijske vaje pisni izpit Delež (v %) / Weight (in %) 30 70 Assessment: Student has to pass successfully the following obligations: Laboratory work Written examination Reference nosilca / Lecturer’s references: ŠKERGET, Mojca, ČUČEK, Denis, KNEZ, Željko. Phase equilibria of the propylene glycol/CO2 and propylene glycol/ethanol/CO2 systems. The Journal of supercritical fluids, ISSN 0896-8446. [Print ed.], Nov. 2014, vol. 95, str. 129-136, doi: 10.1016/j.supflu.2014.08.019. [COBISS.SI-ID 18135574] ČUČEK, Denis, PERKO, Tina, ILIĆ, Ljiljana, ZNOJ, Bogdan, VENTURINI, Peter, KNEZ, Željko, ŠKERGET, Mojca. Phase equlibiria[!] and diffusivity of dense gases in various polyethylenes. The Journal of supercritical fluids, ISSN 08968446. [Print ed.], June 2013, vol. 78, str. 54-62, doi: 10.1016/j.supflu.2013.03.020. [COBISS.SI-ID 16830998], ŠKERGET, Mojca, MANDŽUKA, Zoran, MARKOČIČ, Elena, KNEZ, Željko, JEŠE, Robi, ZNOJ, Bogdan, VENTURINI, Peter. Solubility and diffusivity of CO2 in carboxylated polyesters. The Journal of supercritical fluids, ISSN 0896-8446. [Print ed.], Jan. 2010, vol. 51, iss. 3, str. 306-311, doi: 10.1016/j.supflu.2009.10.013. [COBISS.SI-ID 13799446] KNEZ, Željko, ŠKERGET, Mojca, KNEZ HRNČIČ, Maša, ČUČEK, Denis. Particle formation using sub- and supercritical fluids. V: ANIKEEV, Vladimir (ur.), FAN, Maohong (ur.). Supercritical fluid technology for energy and environmental applications. Amsterdam: Elsevier, 2014, str. 31-67, doi: 10.1016/B978-0-444-62696-7.00002-2. [COBISS.SI-ID 17592854] ŠKERGET, Mojca. Formuliranje prašnih lakov z visokotlačnim postopkom : zaključno poročilo o rezultatih raziskovalnega projekta. Maribor: Fakulteta za kemijo in kemijsko tehnologijo, 2011. loč. pag. [COBISS.SI-ID 14953238] 80 Teorija membranskih transportov Predmet: Course title: UČNI NAČRT PREDMETA / COURSE SYLLABUS Teorija membranskih transportov Theory of Membrane Transport Študijski program in stopnja Study programme and level Študijska smer Study field Letnik Academic year Semester Semester 2. Zimski Autumn Kemijska tehnika / 2. stopnja Chemical Engineering / 2nd level Vrsta predmeta / Course type: Izbirni / Optional Univerzitetna koda predmeta / University course code: Predavanja Lectures Seminar Seminar Sem. vaje Tutorial 15 Nosilec predmeta / Lecturer: Jeziki / Languages: Lab. vaje Laboratory work 15 Teren. vaje Field work Samost. delo Individ. work ECTS 150 6 Irena Petrinić Predavanja / Lectures: slovenščina / Slovene Vaje / Tutorial: slovenščina / Slovene Pogoji za vključitev v delo oz. za opravljanje študijskih obveznosti: Splošno znanje fizike, kemije in matematike. Prerequisits: Vsebina: Membranski proces je proces separacije, ki zajema širok spekter problemov, od delcev do molekul. Na voljo so različne membrane za izvedbo procesov. Četudi so membrane lahko iz različnih materialov(organskega ali anorganskega izvora) in različne strukture ( porozne ali nepozorne), je osnovni princip ločevanja enak. Ta predmet vključuje: Zgodovinski pregled razvoja membran Membrane in klasifikacija membranskih procesov Pretok skozi porozne/neporozne membrane Mehanizmi mašenja Upad pretoka Membranski procesi v okoljski tehnologiji: proizvodnja pitne vode, recikliranje odpadne vode, dodatno čiščenje vode Content (Syllabus outline): A membrane process is a separation process that covers a broad range of problems from particles to molecules and a wide variety of membranes are available to design a process. Although the membranes may vary in material (organic, inorganic) and structure (porous, nonporous) the basic principle of membrane separation is the same. This course covers: An overview of the historical development of membranes Membranes and classification of membrane processes Transport through porous/nonporous membranes Fouling mechanisms Flux decline Membrane processes in environmental General knowledge of chemistry, physics and mathematics 81 Seminarske vaje: Vaje se navezujejo na tematiko predmeta. Študent samostojno reši nekaj praktičnih primerov technology: production of drinking water, recycling of wastewater, additional polishing Tutorials will be based on chosen topic regarding the theme of the subject. Students individually solve several practical examples. Temeljni literatura in viri / Readings: Mulder, Marcel, Basic Principles of Membrane Technology, Kluwer Academic Publishers, Dordrecht, Netherlands, 2003. Baker, R.W., Membrane technology and applications, 2nd ed., John Wiley, 2012. Dodatna priporočena literatura: Judd, S. Jefferson, B. Membranes for Industrial Wastewater Recovery and re-use. New York: Elsevier Advanced Technology, 2003. Noble, Richard D., Stern, S. Alexander (Eds), Membrane Separations Technology - Principles and Applications, Elsevier, 1995. Primarna literatura (npr. članki) s tematiko glede na študentovo področje raziskovanja /Primary literature (e.g. papers) corresponding to the student’s research interest. Cilji in kompetence: Cilj predmeta je, da študentje pridobijo: Pregled osnov membranske filtracijske tehnologije, membrane, in oblike membranskih modulov, membranskih filtracijskih sistemov in uporabo membranskih filtracij na področju obdelave odpadne vode Pridobili bodo znanje membranske tehnologije in membranskih procesov ter njihovih aplikacij Študenti bodo razvili sposobnost oblikovanja in reševanja inženirskih problemov, ki vključuje oblikovanje membran in membranskih modulov Zagotoviti razumevanje splošnih načel separacijskih procesov, da študent vidi možnosti na dejanskih primerih separacijskih procesov Objectives and competences: This course aims to give students: An overview of the fundamentals of membrane filtration technology, membranes and membrane modules configuration, membrane filtration system configurations and membrane applications in the field of wastewater treatment They will get the knowledge of membrane technology, membrane processes and applications To develop the student's ability to formulate and solve engineering problems involving design of membranes and membrane modules To provide an understanding of the general principles of separation processes to allow students to make sensible options given a separation task Predvideni študijski rezultati: Znanje in razumevanje: S pridobitvijo znanja teorije, mehanizma delovanja in tehnološkega razvoja bo študentom dalo orodje za uporabo te relativno nove tehnologije tekom svojih raziskovanj in tudi na njihovih prihodnjih delovnih mestih. Študent bo pridobil izkušnje in znanje na osnovi individualnega raziskovalnega dela. Intended learning outcomes: Knowledge and understanding: By getting knowledge on the theory, mechanism and technology development, this will give the students new tools in using this relatively new technology in their research and also in their future jobs. The student shall gain experience and knowledge with regard to individual, scientific work. Transferable/Key Skills and other attributes: Ability to determine the optimal membrane process, and predict membrane fouling for specific wastewater treatment Prenesljive/ključne spretnosti in drugi atributi: Sposobnost izbrati optimalni membranski proces in napovedati mehanizem mašenja membran gleda na specifičnost odpadne vode. 82 Metode poučevanja in učenja: Pristop temelji na samostojnem delu študenta ob sodelovanju učiteljev (priprava na seminarske naloge, predstavitev seminarskih nalog, konzultacije z učitelji, priprava na izpit in izpit). Načini ocenjevanja: Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: seminarska naloga pisni izpit ustni izpit Learning and teaching methods: The approach is based on the student's own work in cooperation with teachers (preparation for the seminar, seminar presentations, consultations with teachers, preparing for the exam and the exam). Delež (v %) / Weight (in %) Assessment: Student has to pass successfully the following obligations: individual paper 30 40 written examination 30 oral examination Reference nosilca / Lecturer’s references: KRIŽAN, Janja, PETRINIĆ, Irena, GORŠEK, Andreja, SIMONIČ, Marjana. Ultrafiltration of oil-in-water emulsion by using ceramic membrane : Taguchi experimental design approach. Central European Journal of Chemistry, ISSN 1895-1066, Feb. 2014, vol. 12, iss. 2, str. 242-249 BAUMAN, Maja, KOŠAK, Aljoša, LOBNIK, Aleksandra, PETRINIĆ, Irena, LUXBACHER, Thomas. Nanofiltration membranes modified with alkoxysilanes : surface characterization using zeta-potential. Colloids and surfaces. A, Physicochemical and Engineering Aspects, ISSN 0927-7757. [Print ed.], 5. Apr. 2013, vol. 422, str. 110-117 VERLIEFDE, A. R. D., CORNELISSEN, E. R., HEIJMAN, S. G. J., PETRINIĆ, Irena, LUXBACHER, Thomas, AMY, Gary L., BRUGEN, B. van der, DIJK, J. C. van. Influence of membrane fouling by (pretreated) surface water on rejection of pharmaceutically active compounds (PhACs) by nanofiltration membranes. Journal of membrane science, ISSN 0376-7388. [Print ed.], Mar. 2009, vol. 330, iss. 1/2, str. 90-103 83 Transportni pojavi v bioloških sistemih in tehnologija biomimetike Predmet: Course title: UČNI NAČRT PREDMETA / COURSE SYLLABUS Transportni pojavi v bioloških sistemih in tehnologija biomimetike Transport phenomena in biological systems and biomimetic technology Študijski program in stopnja Study programme and level Študijska smer Study field Letnik Academic year Semester Semester 2. Zimski Autumn Kemijska tehnika / 2. stopnja Chemical Engineering / 2nd level Vrsta predmeta / Course type: Izbirni / Optional Univerzitetna koda predmeta / University course code: Predavanja Lectures Seminar Seminar Sem. vaje Tutorial 15 Nosilec predmeta / Lecturer: Jeziki / Languages: Lab. vaje Laboratory work 15 Teren. vaje Field work Samost. delo Individ. work ECTS 150 6 Claus Hélix-Nielsen Predavanja / Lectures: angleščina / English Vaje / Tutorial: angleščina / English Pogoji za vključitev v delo oz. za opravljanje študijskih obveznosti: Osnovno znanje splošne in anorganske kemije, matematike in fizike. Prerequisits: Vsebina: Predmet zajema tri glavne teme z naslovi: Biomolekule (sestava beljakovin in membrane) in njihovo delovanje Celice: lastnosti in delovanje izbranih celic, celična mehanika Transport fluidov in osmozni pojavi v nano območju, biomembrane in prenos snovi skozi membrano Content (Syllabus outline): The course includes three main thematic topics: Biomolecules (protein and membrane components) and their function. Cells: properties and function of selected cells, cellular mechanics. Transport of fluidics and osmotics phenomenom in nanoscale size, biomembranes and membrane transport. Computer Exercises: Calculation of fluid transport and osmotic phenomenon in nanoscale size of biological systems. Project assignment. Računalniške vaje: Izračuni transportov fluidov in osmoznih pojavov v nano območju bioloških sistemov. Projektna naloga. Basic knowledge of general and inorganic chemistry, mathematics and physics. 84 Temeljni literatura in viri / Readings: Claus Hélix-Nielsen, Biomimetic membranes for sensor and separation applications. Chapters 2, 3, 4, 7, and 9. Springer Verlag, 2012. http://link.springer.com/book/10.1007%2F978-94-007-2184-5. Dodatna priporočena literatura: Julian Lewis, Peter Walter, Alexander Johnson, Keith Roberts, Martin Raff & Bruce Alberts, Molecular Biology of the Cell. Chapters 3, 10 and 11. Garland Science, 2008. Rodney Cotterill, Biophysics – an Introduction. Chapters 5, 6, 8, and 11. Wiley, 2002. Cilji in kompetence: Predmet predstavi izbrane sodobne teme, ki povezujejo področja med biofiziko, mikro in nanovelikostjo fizike. V Laboratoriju za vodno biofiziko in membranske procese (LWB) bomo uvedli nove raziskovalne dejavnosti. V beljakovinah, celicah, biomembranah in organizmih se bodo proučevale kompleksne biološke strukture in njihovo delovanje. Obravnavani bodo nanotehnološki in biomimetični pristopi za testiranje biofizikalnih struktur in procesov. Študenti bodo pridobili osnovna znanja in izkušnje pri iskanju strokovne literature v nastajajočem interdisciplinarnem področju, kar jim bo omogočilo nadaljnje raziskovanje/nadgrajevanje z izvedbo lastnih raziskovalnih projektov. Objectives and competences: The course introduces selected contemporary topics at the interface between biophysics and micro- and nanoscale physics. At the same time, research activities at the Laboratory for Water Biophysics and membrane processes (LWB) are introduced. Complex biological structures and their function are studied, ranging from proteins, cells, biomembranes to organisms. Nanotechnological and biomimetic approaches for probing biophysical structures and processes will be discussed. Participants will obtain the basic knowledge and skills for understanding the research literature in an emerging interdisciplinary field and will be able to consider and perform future research projects of their own. Predvideni študijski rezultati: Znanje in razumevanje: Z osvojenimi cilji bo študent lahko: • razumel in uporabljal podatkovne baze biomolekurnih struktur in zaporedij • pojasnil celično sestavo odgovorno za mehanske lastnosti celic • opredelil strukturne in funkcionalne elemente biomembran • obrazložil transportne pojave skozi membrano, vključno z difuzijo, aktivnim transportom, pospešenim transportom in osmotskim transportom • pojasnil osnovni koncept toka tekočine v mikro-merilu bral, razumel in predstavil sodobne interdisciplinarne raziskovalne članke s področja biofizike, biotekočin in biomimetike Intended learning outcomes: A student who has met the objectives of the course will be able to: • Understand and use databases of bio-molecular structures and sequences • Explain the cellular constituents responsible for mechanical properties of cells • Explain defining structural and functional elements of biomembranes • Explain membrane transport phenomena including barrier diffusion, active transport, facilitated transport and osmotic transport • Explain the basic concepts of fluid flow at the micrometer scale Read, understand and present contemporary interdisciplinary research articles in the field of biophysics, biofluidics, and biomimetics. 85 Metode poučevanja in učenja: Predavanja, učenjev skupinah na določenih nalogah/problemih in pisanje poročil. Learning and teaching methods: Lectures, problem based learning in groups, and writing report. Delež (v %) / Načini ocenjevanja: Weight (in %) Assessment: Izpit je opravljen, če so pozitivno opravljene vse Student has to pass successfully the naslednje obveznosti: following obligations: Ustni izpit Oral exam 50 Projektno poročilo Project report 50 Reference nosilca / Lecturer’s references: Nielsen, C.H. Biomimetic membranes for sensor and separation applications. Anal. Bioanal. Chem. 395, 697-718, 2009. Nielsen, C.,H. Protein-lipid interactions in Biological Membranes. In Bohr, H. (ed.) Handbook of Molecular Biophysics, 329-358, Wiley-VC Berlin, Germany, 2009. ISBN-10: 3527407022. Hélix-Nielsen, C. Biomimetic membranes for sensor and separation applications. Springer Verlag ISBN 978-94-0072183-8, 2012. 86 Novi biotehnološki pristopi in aplikacije Predmet: Course title: UČNI NAČRT PREDMETA / COURSE SYLLABUS Novi biotehnološki pristopi in aplikacije Novel Biotechnological Approaches and Applications Študijski program in stopnja Study programme and level Študijska smer Study field Letnik Academic year Semester Semester 2. Zimski Autumn Kemijska tehnika / 2. stopnja Chemical Engineering / 2nd level Vrsta predmeta / Course type: Izbirni / Optional Univerzitetna koda predmeta / University course code: Predavanja Lectures Seminar Seminar Sem. vaje Tutorial 15 Nosilec predmeta / Lecturer: Jeziki / Languages: Lab. vaje Laboratory work 15 Teren. vaje Field work Samost. delo Individ. work ECTS 150 6 Martin Koller Predavanja / Lectures: angleščina / English Vaje / Tutorial: angleščina / English Pogoji za vključitev v delo oz. za opravljanje študijskih obveznosti: Ni. Prerequisits: Vsebina: Izbrana poglavja iz mikrobiologije in osnov tehnologije čistih prostorov (Cleanroom) Mikrobiološki razvoj in mikrobiološka sistematika; “Drevo življenja” Gibljivost mikrobov (kemotaksa, aerotaksa, magnetotaksa, bički itd. Mikrobiološke strategije za pridobivanje biomase in energije (autotrofni in heterotrofni organizmi, metabolične poti itd.) Vloga mikrobov pri naravnem ciklu kemijskih elementov (C, O, N, P, S) Antibiotiki: razredi, različni akcijski mehanizmi, tveganja in izzivi Principi načrtovanja čistih prostorov (Cleanrooms): definicija, različni razredi in nivoji istih prostorov Rizične skupine mikrobov: ravnanje in zakonski predpisi Content (Syllabus outline): Selected Chapters of Microbiology and Basics of Cleanroom Engineering Microbial evolution and microbial systematic; Tree of Life Motility of microbes (chemotaxis, aerotaxis, magnetotaxis, flagellates, etc.) Microbial strategies for biomass- and energy generation (autotrophic and heterotrophic organisms, metabolic pathways, etc.) The role of microbes in the natural cycles of the chemical elements (C, O, N, P, S) Antibiotics: Classes, different mechanisms of action, risks and challenges Principles of Cleanroom Engineering: Definition and different classes and levels of cleanrooms Risk groups of microbes: Handling, Legislative conditions New Approaches to Industrial Biotechnology None. 87 Novi pristopi k Industrijski biotehnologji (“Bela biotehnologija”) Izbrani biotehnološki produkti narekujejo uporabo industrijskih odpadkov in presežnih materialov, kot npr. sirotke iz mlečne industrije, stranskih produktov iz proizvodnje biodizla, odpadnih maščob rastlinskega in živalskega izvora, (ligno)celuloza Podrobnosti: razpoložljivost surovin v odvisnosti od globalne regijske in sezonske razpoložljivosti, izzivi in posebnosti pri njihovi pripravi in presnovi, ter perspektive tržnega uvajanja produktov Poli(hidroksialkanoati) (PHA) kot biotehnologična alternativa za sodobno proizvedene tehnomere (termoplaste in elastomere): genetske, encimske, metabolične in tehnološke osnove, tehnike; izzivi pri separacijah teh materialov in njihova uporaba za specialne produkte (farmacevtske, medicinske, agroindustrijske itd…) - posebno poglavje: autotrofna, miksotrofna in heterotrofna proizvodnja poli(hidroksialkanoatov) z izbranimi fototrofnimi mikrobi - posebno poglavje: pilotna in industrijska proizvodnja PHA iz različnih biogenih surovin; primeri različnih globalnih regij - posebno poglavje: novi procesno tehnološki pristopi za proizvodnjo PHA za izboljšanje kvalitete in kvantitete proizvodnje biopolimerov (npr. večstopenjski kontinuirni procesi) in razvoj novih vrst biogenih tehnomerov, npr. blok polimerov Primarni in sekundarni produkti iz extremophile archaea (pigmenti, specialni ogljikovodiki, inertni citoplazmatski produkti, halocini) Prokariotski mikrobi s sposobnostjo tvorjenja spor kot proizvajalci različnih ciljnih produktov (biotehnološki aceton, izopropanol, nastanek butanola, proizvodnja insekticidov z bacilli) Podrobnosti: posebnosti gojenja takšnih sevov, kinetične značilnosti tvorbe produktov, prednosti in slabosti v primerjavi s kemijsko proizvodnjo Biovodik kot nosilec prihodnje zelene energije: Biotehnološka proizvodnja, izzivi, perspektiva in primerjava z drugo, tretjo in četrto generacijo biogoriv Napredne filtracijske tehnike za industrijske biotehnološke aplikacije (membrane iz votlih vlaken za mikro-, ultra-, nanofiltracijo in reverzno ozmozo) (White Biotechnology) Selected biotechnological products form the application of industrial waste- and surplus materials feedstock, namely: whey from dairy industry, side streams from the biodiesel production, waste lipids of phytal and animal origin, (Ligno)cellulosics Details: Availability of the raw materials in dependence on the global region and seasonal availability, challenges and particularities in their upstream processing and conversion, and perspectives of market penetration of the products Poly(hydroxyalkanoates) (PHAs) as biotechnological alternative for contemporarily produced technomers (thermoplasts and elastomers): Genetic, enzymatic, metabolic and engineering Fundamentals, techniques; challenges in downstream processing of these materials, and their application for bulk and niche products (packaging, pharmaceutical, medical, agroindustrial, etc.). - Special section about: Autotrophic, mixotrophic and heterotrophic production of poly(hydroxyalkanoates) by selected phototrophic microbes - Special section about: Pilot- and industrial scale production of PHA starting from different biogenic feedstocks; case studies from different global regions - Special section about: New process engineering aproaches for PHA production to enhance quality and quantity of biopolymer production (e.g. multistage-continuous processes), and to design new types of biogenic technomers (e.g. blockpolymers) Primary and secondary products from extremophile archaea (pigments, special carbohydrates, inert cytoplasmatic compounds, halocins) Sporeforming prokaryotic microbes as producers of various bulk- and niche products (biotechnological acetone, isopropanol, butanol formation, production of insecticides by Bacilli. Details: Particularities in the cultivation of such production strains; kinetic particularities of product formation, advantages and disadvantages in comparison to chemical production. Biohydrogen as a future-oriented »green energy carrier«: Biotechnological production, challenges, prospective, and comparison to other 2nd, 3rd, and 4th generation biofuels. Advanced filtration techniques for large-scale biotechnological application (Hollow fiber 88 Laboratorijske vaje: Splošno ravnanje z bioreaktorji Gojenje kvasovk v bioreaktorju (regulacija procesa in analiza kinetike) Gojenje izbranega biopoliestra (PHA) za proizvodnjo prokariontskih vrst v bioreaktorju (regulacija in zaključni procesi za čiščenje produkta, analiza kinetike) Gojenje fototrofnih mikroalg v fotobioreaktorju (regulacija, analiza kinetike, zaključni procesi za čiščenje olj iz mikroalg kot potencialne surovine za biodizel 3. generacije) Določanje celične mase v tekočih kulturah (centrifuguranje, filtracija, liofilizacija, infrardeča bilanca itd.) Barvanje celic za ponazoritev organel in inkluzij (jedra, spore, inertne citoplazemske inkluzije, bički) membranes for micro-, ultra-, nanofiltration and reversed osmosis) Labor work General handling of bioreactors Cultivation of yeast in bioreactor (together with process control, and kinetic analysis) Cultivation of a selected biopolyester (PHA) producing prokaryotic species in bioreactor (together with process control, downstream processing for product recovery, and kinetic analysis) Cultivation of a selected phototrophic microalgal species in photobioreactor (together with process control, kinetic analysis, and downstream processing for recovery of microalgal oil as potential 3rd-generation biodiesel feedstock Determination of cell mass in liquid cultures (centrifugation, filtration, lyophylization, infrared balance etc.) Cell staining for visualization of organelles and inclusions (nucleus, spores, inert cytoplasmatic inclusions, flagella) Temeljni literatura in viri / Readings: Scriptum provided by lecturer Selected original (primary and secondary) literature provided by lecturer (also own publications) Koller, M.: Designs of Closed Photobioreactors for Algal Cultivation. – in: Algal Biorefeneries Vol. II (submitted; publication expected in 2015) (Springer; book chapter) Dodatna priporočena literatura: Koller, M.; Salerno, A.; Braunegg, G. (2013): Polyhydroxyalkanoates: Basics, Production and Applications of Microbial Biopolyesters. - book: Bio-based Plastics: Materials and Applications, pp. 137 – 170 (Wiley) Koller, M.; Salerno, A.; Muhr, A.; Reiterer, A.; Braunegg, G. (2013): Polyhydroxyalkanoates: Biodegradable polymeric materials from renewable resources. Materiali in Tehnologije = Materials and Technology 47(1), 5–12 Cilji in kompetence: Študent bo pridobil naslednja znanja: pilotna in idustrijska biotehnologija za velikokapacitetne in nišne produkte obnovljive surovine za industrijske bioproizvode in uporaba industrijskih presežkov v biotehnologiji analize kinetike na osnovi podatkov, pridobljenih v bioprocesu in končna ocena procesa zaključni procesi za pridobivanje industrijsko pomembnih intracelularnih bioproduktov. Objectives and competences: The main objective is devoted to knowledge in Pilot- and Industrial scale biotechnology for bulkand niche products Renewable raw materials for industrial bioprodcts with special emphasis on industrial surplus streams to be upgraded to feedstocks for biotechnology Kinetic analysis of own elaborated raw data from bioprocess and final process evaluation Downstream processing for recovery of industrially relevant intracellular bioproducts 89 Predvideni študijski rezultati: Znanje in razumevanje: Vrste bioproduktov in substratov ter mikrobov za njihovo proizvodnjo Mikrobne strategije za proizvodnjo biomase in energije Osnovno znanje o antibiotikih Gojenje različnih mikrobov v laboratorijskem bioreaktorju, spremljanje, nadzor in ocean vrednotenje procesa Intended learning outcomes: Knowledge and Understanding: Range of different bioproducts and accessible substrates and microbes to produce them Microbial strategies for biomass- and energy production Basic knowledge about antibiotics Performing cultivation of different microbes in laboratory bioreactors with accompanying process monitoring and subsequent process evaluation Prenesljive/ključne spretnosti in drugi atributi: razumevanje prednosti, slabosti in izzivov bioproizvodnje razumevanje celovitih okoljskih in ekonomskih vplivov kemijske in biokemijske proizvodnje razumevanje različnih zahtev različnih mikrobov seznanitev z industrijsko pomembnimi mikroorganizmi. Transferable/Key Skills and other attributes: Understanding the advandages, drawbacks, and challenges of bio-based production. Understanding the holistic environmental and economic impacts of chemical vs. biochemical production strategies Understanding different requirements of different microbes Getting familiar with industrially relevant microorganisms Metode poučevanja in učenja: predavanja samostojno seminarsko delo za končno ustno predstavitev laboratorijskih rezultatov (skupinsko ali posamezno) samostojno seminarsko delo za ustno predstavitev izbrane izvirne literature (skupinsko ali posamezno) samostojno učenje Learning and teaching methods: Lectures Independent seminar work for final oral presentation of laboratory results (group or single) Independent seminar work for oral presentation of selected original literature (group or single) Self-learning Delež (v %) / Načini ocenjevanja: Weight (in %) Assessment: Izpit je opravljen, če so pozitivno opravljene vse Student has to pass successfully the naslednje obveznosti: following obligations: 25 Pisni izpit Final written examination 12,5 Ustna predstavitev laboratorijskih Oral presentation of own laboratory rezultatov results Ustna predstavitev izbranih tem Oral presentation on selected topics 12,5 25 Izvedba kinetične analize eksperimentalnih Evaluation of kinetic analysis of own podatkov, pridobljenih v izvedenem experimental raw data from the bioprocesu accomplished bioprocesses 25 Aktivno sodelovanje Active collaboration Reference nosilca / Lecturer’s references: Koller, M.; Chiellini, E., Braunegg, G. (2015): Study on the production and re-use of poly(3-hydroxybutyrate-co-3hydroxyvalerate) and extracellular polysaccharide by the archaeon Haloferax mediterranei strain DSM 1411 Chemical and Biochemical Engineering Quarterly 29(2); in press. Koller, M.; Muhr, A., Braunegg, G. (2014): Microalgae as versatile cellular factories. Algal Research 6(A), 53-63. Koller, M.; Bona, R.; Braunegg, G.; Hermann, C.; Horvat, P.; Kroutil, M.; Martinz, J.; Neto, J.; Varila, P.; Pereira, L. (2005): Production of polyhydroxyalkanoates from agricultural waste and surplus materials. Biomacromolecules 6(2), 561–565. 90 FP 7 EU-Project ANIMPOL ‘Biotechnological conversion of carbon containing wastes for eco-efficient production of high added value products’ (Grant number 245084): Coordinator and Person in charge for the administrative, financial, scientific and technical aspects of the project (2010-2013): Most relevant references: Muhr, A.; Rechberger, E. M.; Salerno, A.; Reiterer, A.; Schiller, M.; Kwicien, M.; Adamus, G.; Kowalczuk, M.; Strohmeier, K.; Schober, S.; Mittelbach, M.; Koller, M. (2013): Biodegradable latexes from animal-derived waste: Biosynthesis and characterization of mcl-PHA accumulated by Ps. citronellolis. Reactive & Functional Polymers 73(10), 1391–1398 Shahzad, K.; Kettl, K.-H.; Koller, M.; Titz, M.; Schnitzer, H.; Narodoslawsky, M. (2013): Comparison of ecological footprint for biobased PHA production from animal residues utilizing different energy resources. Clean Technologies and Environmental Policy 15(3), 525–536 91 Encimske tehnologije Predmet: Course title: UČNI NAČRT PREDMETA / COURSE SYLLABUS Encimske tehnologije Enzyme Technologies Študijski program in stopnja Study programme and level Kemijska tehnika / 2. stopnja Chemical Engineering / 2nd level Študijska smer Study field Biokemijska tehnika Biochemical Engineering Vrsta predmeta / Course type: Letnik Academic year 2. Semester Semester zimski Autumn Izbirni / Optional Univerzitetna koda predmeta / University course code: Predavanja Lectures 15 Seminar Seminar Nosilec predmeta / Lecturer: Jeziki / Languages: Sem. vaje Tutorial Lab. vaje Labor work 15 Teren. vaje Field work Samost. delo Individ. work 150 ECTS 6 Maja Leitgeb Predavanja / Lecture: slovenski / Slovene Vaje / Tutorial: slovenski / Slovene Pogoji za vključitev v delo oz. za opravljanje študijskih obveznosti: Potrebno je znanje iz bioseparacijske tehnike in biokatalize ter industrijske mikrobiologije. Prerequisites: Vsebina: Izolacija in priprava encimov. Imobilizacija. Uporaba encimov (detergenti, tekstilije, papir, živalska krma). Encimi kot biokatalizatorji (osnovne kemikalije, fine kemikalije, hrana, farmacevtske učinkovine). Farmacevtska aplikacija biokatalize (inhibicija encimov za boj proti boleznim, specifične biokatalizne reakcije v farmaciji). Sintetični encimi. Content (Syllabus outline): Isolation and preparation of enzymes. Imobilization. Application of enzymes (detergents, textilles, pulp and paper, animal feed). Application of enzymes as biocatalysts (basic chemicals, fine chemicals, food, pharmaceuticals). Pharmaceutical application of biocatalysis (enzyme inhibition for the fight against disease, specific biocatalytic reactions in pharma). Artificial enzymes. Laboratorijske vaje na konkretnem primeru biokatalizirane proizvodje osnovnih in finih kemikalij ter postopka priprave encimov. Laboratory work on the case of biocatalytic production of basic and fine chemicals, as well as on preparation of enzymes. Knowledge of bioseparation processes and biocatalysis and industrial microbiology is needed. 92 Temeljni literatura in viri / Textbooks: S. Bommarius, B. R. Riebel-Bommarius, Biocatalysis: Fundamentals and Applications, 1st ed., WileyVCH; Darmstadt, 2004. Liese, K. Seelbach, C. Wandrey, Industrial Biotransformations, Wiley-VCH, Weinheim, 2000. Dodatna priporočena literatura: J. A. Tao, R. J. Kazlauskas, Biocatalysis for Green Chemistry and Chemical Process Development, Wiley, ISBN: 978-0-470-43778-0, 2011. M. C. Flickinger, Encyclopedia of Industrial Biotechnology, Bioprocess, Bioseparation, and Cell Technology , 7 Volume Set, Wiley, ISBN: 978-0-471-79930-6, 2010. A. Illanes, L. Wilson, C. Vera, Problem Solving in Enzyme Biocatalysis, Wiley, ISBN: 978-1-118-34171-1, 2013. Cilji in kompetence: Pregled metod izolacije in čiščenja encimov ter aplikacija posameznih encimov v biotransformacijah. Objectives and competences: Overview of enzyme isolation and purification methods and application of enzymes in biotransformations. Predvideni študijski rezultati: Znanje in razumevanje: Poznavanje proizvodnje encimov, njihove stabilnosti in produktivnosti ter uporabe v biosintezi. Intended learning outcomes: Knowledge and Understanding: Knowledge of enzyme production, their stability and productivity, as well as their application in biosynthesis. Prenesljive/ključne spretnosti in drugi atributi: Predmet se dopoljnjuje z ostalimi vsebinami na smeri Biokemijska tehnika. Transferable/Key Skills and other attributes: The subject is related to the other subjects on the study field Biochemical engineering. Metode poučevanja in učenja: Predavanja v učilnici, ki je opremljena z avdiovizualnimi pripomočki. Individualna priprava seminarskih nalog s predstavitvijo in diskusijo. Laboratorijsko delo na izbranem primeru. Learning and teaching methods: Lectures in lecture room, equipped with audio-visual equipment Individual preparation of seminars and their presentation with discussion. Laboratory work on a selected case. Načini ocenjevanja: Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: - laboratorijsko delo - seminarska naloga - ustni izpit Delež (v %) / Weight (in %) 30 30 40 93 Assessment: Student has to pass successfully the following obligations: - laboratory work - seminary work - oral examination Reference nosilca / Lecturer’s references: KNEZ, Željko, KAVČIČ, Sabina, GUBICZA, László, BÉLAFI-BAKÓ, Katalin, NÉMETH, Gergely, PRIMOŽIČ, Mateja, LEITGEB, Maja. Lipase-catalyzed esterification of lactic acid in supercritical carbon dioxide. The Journal of supercritical fluids, ISSN 0896-8446. 2012, 66, 192-197, doi: 10.1016/j.supflu.2011.11. [COBISS.SI-ID 15598102] ŠULEK, Franja, PÉREZ FERNÁNDEZ, Daniel, KNEZ, Željko, LEITGEB, Maja, SHELDON, Roger A. Immobilization of horseradish peroxidase as crosslinked enzyme aggregates (CLEAs). Process biochemistry, ISSN 1359-5113, 2011, 46 (3), 765-769, doi: 10.1016/j.procbio.2010.12.001. [COBISS.SI-ID 14712598] CSANÁDI, Zsófia, BÉLAFI-BAKÓ, Katalin, SZENTGYÖRGYI, Eszter, GUBICZA, László, KNEZ, Željko, LEITGEB, Maja. Enzymatic esterification of glycerol and stearic acid in non-conventional media. Acta chimica slovenica, ISSN 13180207. 2010, 57 (1), 244-249. COBISS.SI-ID 14029590] ŠULEK, Franja, KNEZ, Željko, LEITGEB, Maja. Immobilization of cholesterol oxidase to finely dispersed silica-coated maghemite nanoparticles based magnetic fluid. Applied Surface Science, ISSN 0169-4332. 2010, 256 (14), 45964600. [COBISS.SI-ID 14055446] THOREY, Paul, KNEZ, Željko, LEITGEB, Maja. Alcohol dehydrogenase in non-aqueous media using high-pressure technologies : reaction set-up and deactivation determination. Journal of chemical technology and biotechnology, ISSN 0268-2575. 2010, 85, 1011-1016. [COBISS.SI-ID 14291222] 94 Sodobna biokataliza Predmet: Course title: UČNI NAČRT PREDMETA / COURSE SYLLABUS Sodobna biokataliza Modern biocatalysis Študijski program in stopnja Study programme and level Kemijska tehnika / 2. stopnja Chemical Engineering / 2nd level Študijska smer Study field Biokemijska tehnika Biochemical Engineering Vrsta predmeta / Course type: Letnik Academic year 2. Semester Semester zimski Autumn Izbirni / Optional Univerzitetna koda predmeta / University course code: Predavanja Lectures 15 Seminar Seminar Nosilec predmeta / Lecturer: Jeziki / Languages: Sem. vaje Tutorial Lab. vaje Labor work 15 Teren. vaje Field work Samost. delo Individ. work 150 ECTS 6 Maja Leitgeb Predavanja / Lecture: slovenski / Slovene Vaje / Tutorial: slovenski / Slovene Pogoji za vključitev v delo oz. za opravljanje študijskih obveznosti: Potrebno je znanje iz bioseparacijske tehnike in biokatalize ter industrijske mikrobiologije. Prerequisites: Vsebina: Encimi v organskih topilih (prednosti, bifazne reakcije, separacija, stabilnost encimov, selektivnost encimov). Prednosti biokatalize v organskih topilih. Korelacija med delovanjem encimov in parametri topila (variacija hidrofobnosti – log P, enantioselektivnost in polarnost topila ter hidrofobost). Optimalno rokovanje z encimi v organskih topilih. Novejši reakcijski mediji za biokatalizo (substrat kot topilo, superkritični fluidi, ionske tekočine, emulzije, mikroemulzije, tekoči kristali). Topilo kot parameter za optimiranje reakcije (»medium engineering«). Content (Syllabus outline): Enzymes in organic solvents (advantages, biphasic reactions, separation, enzyme stability, selectivity of enzymes). Advantages of biocatalysis in organic solvents. Correlation between enzyme performance and solvent parameters (variation of hydrophobicity – log P, enantioselectivity and solvent polarity and hydrophobicity). Optimal handling of enzymes in organic solvents. Novel reaction media for biocatalysis (substrate as a solvent, supercritical fluids, ionic liquids, emulsions, microemulsions, liquid crystals). Solvent as a parameter for reaction optimization (»medium engineering). Laboratorijske vaje iz področja encimsko kataliziranih reakcij v nekonvencionalnih medijih, npr. v plinih visoke gostote, ionskih tekočinah, … Laboratory work in the field of enzymatic reactions in nonconventional media, e.g. supercritical fluids, ionic liquids, etc. Knowledge of bioseparation processes, biocatalysis and industrial microbiology is needed. 95 Temeljni literatura in viri / Textbooks: A. S. Bommarius, B. R. Riebel-Bommarius, Biocatalysis: Fundamentals and Applications, 1st ed., WileyVCH; Darmstadt, 2004. K. Faber, Bio-transformations in Organic Chemistry, 6th ed., Springer-Verlag, Berlin, 2011. Dodatna priporočena literatura: P.G. Jessop, W. Leitner, Chemical Synthesis Using Supercritical Fluids, Wiley-VCH, Weinheim, online 2007. P. Wasserscheid, T. Welton, Ionic Liquids in Synthesis, 2nd ed., Wiley-VCH, Weinheim, 2007. Cilji in kompetence: Pregled možnih alternativnih topil za biokatalitične transformacije. Objectives and competences: Overview of possible alternative solvents for biocatalytical transformations. Predvideni študijski rezultati: Znanje in razumevanje: Zmožnost načrtovanja biokataliziranih reakcij v topilih, ki niso voda. Intended learning outcomes: Knowledge and Understanding: Design of biocatalytical reactions in solvents, others than water. Prenesljive/ključne spretnosti in drugi atributi: Predmet se dopoljnjuje z ostalimi vsebinami na smeri Biokemijska tehnika. Transferable/Key Skills and other attributes: The subject is related to the other subjects on the study field Biochemical engineering. Metode poučevanja in učenja: Predavanja v učilnici, ki je opremljena z avdiovizualnimi pripomočki. Individualna priprava seminarskih nalog s predstavitvijo in diskusijo. Laboratorijsko delo na izbranem primeru. Learning and teaching methods: Lectures in a lecture room, equipped with audiovisual equipment Individual preparation of seminars and their presentation with discussion. Laboratory work on selected case. Načini ocenjevanja: Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: - laboratorijske vaje - ustni izpit Delež (v %) / Weight (in %) 40 60 Assessment: Student has to pass successfully the following obligations: - laboratory work - oral examination Reference nosilca / Lecturer’s references: KNEZ, Željko, KAVČIČ, Sabina, GUBICZA, László, BÉLAFI-BAKÓ, Katalin, NÉMETH, Gergely, PRIMOŽIČ, Mateja, LEITGEB, Maja. Lipase-catalyzed esterification of lactic acid in supercritical carbon dioxide. The Journal of supercritical fluids, ISSN 0896-8446. 2012, 66, 192-197, doi: 10.1016/j.supflu.2011.11. [COBISS.SI-ID 15598102] CSANÁDI, Zsófia, BÉLAFI-BAKÓ, Katalin, SZENTGYÖRGYI, Eszter, GUBICZA, László, KNEZ, Željko, LEITGEB, Maja. Enzymatic esterification of glycerol and stearic acid in non-conventional media. Acta chimica slovenica, ISSN 13180207. 2010, 57 (1), 244-249. COBISS.SI-ID 14029590] THOREY, Paul, KNEZ, Željko, LEITGEB, Maja. Alcohol dehydrogenase in non-aqueous media using high-pressure technologies : reaction set-up and deactivation determination. Journal of chemical technology and biotechnology, ISSN 0268-2575. 2010, 85, 1011-1016. [COBISS.SI-ID 14291222] KAVČIČ, Sabina, KNEZ, Željko, LEITGEB, Maja. Antimicrobial activity of n-butyl lactate obtained via enzymatic esterification of lactic acid with n-butanol in supercritical trifluoromethane. The Journal of supercritical fluids, ISSN 0896-8446. 2014, 85, 143-150, doi: 10.1016/j.supflu.2013.11.003. [COBISS.SI-ID 17392406] 96 Farmacevtske učinkovine Predmet: Course title: UČNI NAČRT PREDMETA / COURSE SYLLABUS Farmacevtske učinkovine Active Pharmaceutical Ingredients Študijski program in stopnja Study programme and level Kemijska tehnika / 2. stopnja Chemical Engineering / 2nd level Študijska smer Study field Biokemijska tehnika Biochemical Engineering Vrsta predmeta / Course type: Letnik Academic year 2. Semester Semester zimski Autumn Izbirni / Optional Univerzitetna koda predmeta / University course code: Predavanja Lectures 15 Seminar Seminar Nosilec predmeta / Lecturer: Jeziki / Languages: Sem. vaje Tutorial Lab. vaje Labor work 15 Teren. vaje Field work Samost. delo Individ. work 150 ECTS 6 Igor Simonič Predavanja / Lecture: slovenski / Slovene Vaje / Tutorial: slovenski / Slovene Pogoji za vključitev v delo oz. za opravljanje študijskih obveznosti: Pogojev ni. Prerequisites: Vsebina: - Farmacevtske učinkovine – neformulirana zdravila; klasifikacije in terminologija. - Ekonomski, socialni in strateški vidiki zdravil oz. farmacevtskih učinkovin. - Posebne zahteve in predpisi – učinkovitost, varnost; sistemi kakovosti, dobre prakse v razvoju, proizvodnji in kontroli farmacevtskih učinkovin, validacijske tehnologije; registracijske zahteve in dokumentacija. - Pomen in vplivi fizikalno-kemijskih lastnosti na učinkovitost in varnost; specifikacije kakovosti; vsebnost, čistota, viri in vrste nečistot, strategije obvladovanja nečistot, fizikalni in drugi parametri, stabilnost. - Principi razvoja proizvodnih in kontrolnih tehnologij za farmacevtske učinkovine. - Trendi v razvoju in proizvodnji farmacevtskih učinkovin. - Principi, značilnosti in pomen patentne zaščite Content (Syllabus outline): - Active pharmaceutical ingridients (API) – nonformulated drugs; clasifications and terminology. - Economic, social and strategic aspects of drugs, including API. - Specific requirements and regulations – efficacy and safety; quality systems, good practices in development, production and quality control of API, validation technologies; requirements for registrations and documentation. - Significance of physico-chemical parameters on efficacy and safety; quality specifications; assay, purity, sources and types of impurities, strategies of mastering impurities, physical and other parameters, stability. - Principles of development of production and quality control technologies for API. - Trends in development and production of API. - Principles, characteristics and significance of None. 97 za farmacevtske učinkovine. - Biotehnološke – klasične in rekombinantne, sintetske in polsintetske učinkovine – značilni primeri učinkovin in tehnologij; značilni terapevtski in strukturni tipi. patent protection of API. - Biotechnological – classic and recombinant, synthetic and semisynthetic API – characteristic examples of substances and technologies; characteristic therapeutic and structural types. Temeljni literatura in viri / Textbooks: B. Štrukelj (ur.), J. Kos (ur.), Biološka zdravila: od gena do učinkovine, Slovensko farmacevtsko društvo, Ljubljana, 2007. Dodatna priporočena literatura: J. J. Li, D. S. Johnson, D. Sliskovic, B. D. Roth: Contemporary drug synthesis, John Wiley & Sons, Inc., Hoboken, New Jersey, 2004. O. Repič: Principles of process research and chemical development in the pharmaceutical industry, John Wiley & Sons, Inc., New York, Chichester, Weinheim, Brisbane, Singapore, Toronto, 1998. M. M. Amiji, B. J. Sandmann: Applied physical pharmacy, McGraw-Hill Co. Inc., New York, 2003. European Pharmacopoeia, 4th Edition, EDQM, Strasbourg, 2004 (in druge izdaje ter dodatki). Cilji in kompetence: Študent spozna in razume specifične zahteve za farmacevtske učinkovine ter multidisciplinarnost obvladovanja tega področja; pridobi ključna znanja za načrtovanje in razvoj proizvodnih in kontrolnih tehnologij ter obvladovanje proizvodnje farmacevtskih učinkovin. Usposobi se za delo v timih s strokovnjaki na področju zdravil. Objectives and competences: Student acknowledges and understands specific requirements for API and multidisiplinariness of the field; acquires crucial expertise for planning and developing production and quality control technologies, as well as mastering API production. Student gets qualified for team work in the field of drugs. Predvideni študijski rezultati: Znanje in razumevanje: Študent pozna osnovno terminologijo in klasifikacije, ključne strukturne in terapevtske tipe učinkovin ter značilne tehnologije. Pozna principe in postopke razvoja tehnologij za učinkovine. Razume pomen in medsebojne vplive parametrov kakovosti in jih zna specificirati. Razume principe sistemov kakovosti v razvoju, kontroli kakovosti in proizvodnji. Pozna osnovne predpise za učinkovine ter osnove zaščite intelektualne lastnine in pomen za delo na področju zdravil. Intended learning outcomes: Knowledge and Understanding: Student is familiar with basic terminology and clasifications, crucial structural and therapeutic types of API, as well as characteristic technologies; knows principles and procedures of production and quality control technologies development for API. Uderstands signifiacance and correlations of quality parameters, and is familiar with approaches to determine them. Student understands principles of quality sistems in development, quality control and production of API, and is aware of relevant regulations, as well as of IPR and its relevance for working in the field. Prenesljive/ključne spretnosti in drugi atributi: Študent razvije sposobnost integracije znanj ter reševanja kompleksnih interdisciplinarnih problemov. Transferable/Key Skills and other attributes: Student develops ability to integrate his knowledge, and to solve complex interdisciplinary problems. Metode poučevanja in učenja: Predavanja, seminarske vaje, projektno delo. Learning and teaching methods: Lectures, tutorial and project work. 98 Načini ocenjevanja: Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: - projektno poročilo - pisni izpit Delež (v %) / Weight (in %) 50 50 Assessment: Student has to pass successfully the following obligations: - project report - written examination Reference nosilca / Lecturer’s references: ŠTEFANIČ PETEK, Alenka, JAPELJ, Miha. Synthesis of cephalosporin derivatives with different 3'-nitrogen heterocyclic substituents. Acta pharmaceutica, ISSN 1330-0075, 2000, vol. 50, no. 1, str. 17-27, ilustr. [COBISS.SI-ID 22536709] JAPELJ, Miha. Significance of research and development in the pharmaceutical industry : Pharmaceutical company KRKA, Slovenia, as an example. V: KORNHAUSER FRAZER, Aleksandra (ur.), DASILVA, Edgar (ur.), SAJOVIC, Irena (ur.). Biotechnological intellectual property at universities : scientific, technological, economic, legal and ethical aspects : proceedings of the Workshop - Expert Meeting ICCS, Ljubljana, 21 - 24 February 2001. Ljubljana: Slovenian National Commission for Unesco: International Centre for Chemical Studies (ICCS), 2001, str. 55-57. [COBISS.SI-ID 1157980] ČASAR, Zdenko, LORCY, Dominique, ROBERT, Albert, MAJCEN LE MARECHAL, Alenka, JAPELJ, Miha. Towards diselenadiazafulvalenes : synthesis of precursors. V: Slovenski kemijski dnevi 2000, Maribor, 28. in 29. september 2000. GLAVIČ, Peter (ur.), BRODNJAK-VONČINA, Darinka (ur.). Zbornik referatov s posvetovanja. Maribor: FKKT, 2000, del 1, str. 92-97. [COBISS.SI-ID 5690646] FUJS, Štefan, KUŠČER, Enej, PETKOVIĆ, Hrvoje, SLADIČ, Gordan, GASPARIČ, Aleš. Process for production of lipstatin and microorganisms therefore : European patent application : EP 2 141 236 A1 : application no. 08012016.5. München: Europäisches Patentamt: = European Patent Office: = Office européen des brevets, 06.01.2010. [COBISS.SI-ID 3746168] GASPARIČ, Aleš, SLADIČ, Gordan, BENIČKI-ŠVAGELJ, Neda, PELKO, Mitja, RASPOR, Peter, PETKOVIĆ, Hrvoje, FUJS, Štefan. Fermentative production of lipstatin : patent : EP 2019869 (B1), 2011-03-02. Paris: European Patent Office, 2011. 16 str., ilustr. [COBISS.SI-ID 3890296] SLADIČ, Gordan, URUKALO, Matilda, KIRN, Matjaž, LEŠNIK, Urška, MAGDEVSKA, Vasilka, BENIČKI-ŠVAGELJ, Neda, PELKO, Mitja, GASPARIČ, Aleš, RASPOR, Peter, POLAK, Tomaž, FUJS, Štefan, HOSKISSON, Paul A., PETKOVIĆ, Hrvoje. Identification of lipstatin-producing ability in Streptomyces virginiae CBS 314.55 using dereplication approach. Food technology and biotechnology, ISSN 1330-9862, 2014, vol. 52, no. 3, str. 276-284. [COBISS.SI-ID 4372088] 99 Farmacevtska tehnika Predmet: Course title: UČNI NAČRT PREDMETA / COURSE SYLLABUS Farmacevtska tehnika Pharmaceutical Technology Študijski program in stopnja Study programme and level Kemijska tehnika / 2. stopnja Chemical Engineering / 2nd level Študijska smer Study field Biokemijska tehnika Biochemical Engineering Vrsta predmeta / Course type: Letnik Academic year 2. Semester Semester zimski Autumn Izbirni / Optional Univerzitetna koda predmeta / University course code: Predavanja Lectures 15 Seminar Seminar Nosilec predmeta / Lecturer: Jeziki / Languages: Sem. vaje Tutorial Lab. vaje Labor work 15 Teren. vaje Field work Samost. delo Individ. work 150 ECTS 6 Željko Knez Predavanja / Lecture: slovenski / Slovene Vaje / Tutorial: slovenski / Slovene Pogoji za vključitev v delo oz. za opravljanje študijskih obveznosti: Znanje iz splošne kemije, analizne in fizikalne kemije. Osnove iz mehanike fluidov in prenosnih pojavov. Prerequisites: Knowledge on basic chemistry, analytical and physical chemistry. Basics of fluid mechanics and mass transfer. Vsebina: Farmacevtsko tehnološke operacije: fizikalno kemijske osnove pri načrtovanju farmacevtske oblike (difuzija, adhezija, kohezija, absorpcija, porazdelitev in sproščanje, prenos snovi idr.), osnovne tehnološke operacije (mešanje, mletje, postopki s superkritičnimi fluidi, filtriranje, suspendiranje, steriliziranje, liofiliziranje idr.), splošni vidiki pri načrtovanju farmacevtske oblike (stabilnost in stabilizacija, nekompatibilnosti, materiali in postopki za embalažo, sterilizacija), razvite farmacevtske operacije, stabilnost zdravil. Content (Syllabus outline): Pharmaceutical technology operations: Physico-chemical basics of designing pharmaceutical forms (diffusion, adhesion, cohesion, absorbtion, distribution and elimination of drugs, mass transfer and others), Basic technology operations (mixing, grinding, processes with supecritical fluids, filtration, suspension, sterilization, liophilization and others), Basic aspects for designing pharmaceutical forms (stability and stabilization, uncompatibility, materials and processes for packaging, sterilization), Advanced pharmaceutical operations, Drug stability. Farmacevtske oblike: Pharmaceutical forms: 100 teoretične osnove farmacevtskih oblik kot aplikacijskega in disperzijskega sistema (osnovne in pomožne substance pri načrtovanju farmacevtskih oblik), statične metode pri načrtovanju farmacevtkih oblik, osnove biofarmacije, farmacevstke oblike: trdne, poltrdne, tekoče, plinaste (oblike za inhaliranje), rastlinski izvlečki idr., sodobne oblike zdravil in tendenca razvoja (terapevtski sistemi, potencialne oblike zdravil). Laboratorijske vaje: Študentje spoznajo osnovne farmacevtsko tehnološke operacije (mešanje, mletje, drobljenje, postopki s superkritičnimi fluidi, kompaktiranje, emulgiranje…) in sodobno načrtovanje, oblikovanje in vrednotenje trdnih oblik s poudarkom na izboru pomožnih snovi. Theoretical basics of pharmaceutical forms as an application and dispersion system (basic and auxiliary substances at design of pharmaceutical forms), Static methods for designing pharmaceutical forms, Basics of biopharmacy, Pharmaceutical forms: solids, semi-solids, liquids, gasses (inhalation forms), natural material extracts and others, Modern forms of pharmaceutics and development tendency (therapeutic systems, potential pharmaceutical forms). Laboratory work: Students become familiar with basic pharmaceutical technological operations (mixing, grinding, crushing, processes with supercritical fluids, compaction, emulsification,…) and modern designing, formulation and evaluation of solid forms with emphasis on suppository substance selection. Temeljni literatura in viri / Textbooks: Voigt R., Pharmazeutische Technologie für Studium und Beruf, 11., durchgesehene und ergänzte Auflage 2010. XXIII, 746 S., 317 s/w Abb., 110 s/w Tab., gebunden, Deutscher Apotheker Verlag, ISBN 978-37692-5003-9, 2010. Dodatna priporočena literatura: Roshni L. Dutton, Jeno M. Scharer, Jeno M. Scharer, Advanced Technologies for Biopharmaceutical Processing, Blackwell Pub Professional, ISBN-10: 0813805171, 2006. Cilji in kompetence: Znanje o novih materialih, tehnoloških pristopih in farmacevtskih oblikah. Objectives and competences: Knowledge on new materials, approaches in pharmaceutical forms. Predvideni študijski rezultati: Znanje in razumevanje: Znanje s področja osnovnih tehnoloških operacij in formuliranja farmacevtskih oblik. Prenesljive/ključne spretnosti in drugi atributi: Vsebina predmeta je povezana z ostalimi predmeti na smeri Biokemijska tehnika. Intended learning outcomes: Knowledge and Understanding: Knowledge in the field of basic technological operations and formulation of pharmaceutical forms. Transferable/Key Skills and other attributes: The subject is connected to other subjects in the option Biochemical engineering. Metode poučevanja in učenja: - predavanja - laboratorijske vaje Learning and teaching methods: - lectures - laboratory work. 101 technology Načini ocenjevanja: Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: - laboratorijske vaje - pisni izpit - ustni izpit Delež (v %) / Weight (in %) 10 50 40 Assessment: Student has to pass successfully the following obligations: - laboratory work - written examination - oral examination Reference nosilca / Lecturer’s references: VERONOVSKI, Anja, NOVAK, Zoran, KNEZ, Željko. Synthesis and use of organic biodegradable aerogels as drug carriers. Journal of biomaterials science, Polymer edition, ISSN 0920-5063, 2012, vol. 23, no. 7, str. 873-886. LEITGEB, Maja, PRIMOŽIČ, Mateja, KNEZ, Željko. Biocompatible nanomaterials : synthesis, characterization and applications. V: ACKLIN, Beate (ur.), LAUTENS, Edon (ur.). Magnetic nanoparticles : properties, synthesis and applications, (Physics research and technology), (Nanotechnology science and technology). New York: Nova Science Publishers, 2012, str. 135-156. CÖR, Darija, BOTIĆ, Tanja, KNEZ, Željko, BATISTA, Urška, GREGORI, Andrej, POHLEVEN, Franc, BONČINA, Tonica. Two-stage extraction of antitumor, antioxidant and antiacetylcholinesterase compounds from Ganoderma lucidum fruiting body. The Journal of supercritical fluids, ISSN 0896-8446, 2014, vol. 91, str. 53-60, doi: 10.1016/j.supflu.2014.04.006. LEITGEB, Maja, HOJNIK PODREPŠEK, Gordana, KNEZ, Željko. Magnetic nanocarriers for targeted drug delivery. V: SABBAS, Nora P. (ur.). Magnetic nanoparticles : synthesis, physicochemical properties and role in biomedicine, (Nanotechnology science and technology). New York: Nova Science Publishers, 2014, str. 201-230. KNEZ, Željko, MARKOČIČ, Elena, LEITGEB, Maja, PRIMOŽIČ, Mateja, KNEZ HRNČIČ, Maša, ŠKERGET, Mojca. Industrial applications of supercritical fluids: a review. Energy, ISSN 0360-5442, 2014, str. 1-9, doi: 10.1016/j.energy.2014.07.044. 102 Biokemija, mikrobiologija in molekularna biologija Predmet: Course title: UČNI NAČRT PREDMETA / COURSE SYLLABUS Biokemija, mikrobiologija in molekularna biologija Biochemistry, Microbiology and Molecular biology Študijski program in stopnja Study programme and level Kemijska tehnika / 2. stopnja Chemical Engineering / 2nd level Študijska smer Study field Biokemijska tehnika Biochemical Engineering Vrsta predmeta / Course type: Letnik Academic year 2. Semester Semester zimski Autumn Izbirni / Optional Univerzitetna koda predmeta / University course code: Predavanja Lectures 15 Seminar Seminar Nosilec predmeta / Lecturer: Jeziki / Languages: Sem. vaje Tutorial Lab. vaje Labor work 15 Teren. vaje Field work Samost. delo Individ. work 150 ECTS 6 Uroš Potočnik, Maja Leitgeb Predavanja / Lecture: slovenščina / Slovene Vaje / Tutorial: slovenščina / Slovene Pogoji za vključitev v delo oz. za opravljanje študijskih obveznosti: Osnovna znanja iz mikrobiologije. Prerequisites: Basic knowledge of microbiology. Vsebina: Morfologija mikroorganizmov. Celična struktura. Struktura in funkcija celičnih membran. Celična stena prokariot. Struktura in funkcija subcelularnih organel. Razmnoževanje mikroorganizmov. Komunikacija med celicami in prenos signalov Proteini: struktura in vloga v bioloških procesih, analiza plazemskih proteinov za diagnosticiranje bolezni, analiza aminokislin za diagnosticiranje bolezni, povezave med strukturo in funkcijo v proteinskih družinah, Naddružina imunoglobulinov, DNA vezavni proteini Biološke membrane: zgradba in biološka vloga, aktivni in pasivni transport, liposomi kot prenašalci zdravil in encimov, bolezni, ki so posledica izgube fluidnosti celične membrane in okvare membranskih transportnih sistemov Metabolizem ogljikovih hidratov: glavne metabolne poti in njihova kontrola, posebne metabolne poti, sladkorna bolezen Content (Syllabus outline): Morphology of microorganisms. Cell structure. Structure and function of cell membranes. Cell wall of prokaryotes. Structure and functional role of subcellular organelles Microbial growth. Cell communication and signal transduction Proteins: Architecture and Biological Function, Plasma Proteins in Diagnosis of Disease, Use of Amino Acid Analysis in Diagnosis of Disease, Structure Function Relationships in Protein Families, The Immunoglobulin Superfamily, DNABinding Proteins Biological Membranes: Structure and biological function, Active and passive Membrane Transport, Liposomes as Carriers of Drugs and Enzymes, Diseases Due to Abnormalities of Cell Membrane Fluidity and Loss of Membrane Transport Systems Carbohydrates Methabolism: Major Metabolic Pathways and Their Control, Special Pathways, 103 Osnove molekularne genetike: DNA struktura in lastnosti, replikacija (prokarionti, eukarionti), rekombinacija DNA, DNA popravljalni, mehanizmi, mehanizem nastanka DNA mutacij, organizacija, struktura in funkcija genov, struktura genoma (rastlinski, živalski in človeški), transkripcija, translacija, regulacija genske ekspresije Osnove dedovanja, kromosomska teorija dednosti, Mendlovo dedovanje, poligensko dedovanje Rak Imunski sistem Uporaba mikroorganizmov v raziskavah in industriji Diabetes Mellitus Basic molecular genetics: DNA structure and characteristics, replication (prokaryotes, eukaryotes), recombination, repair and mutations, organization, structure and function of genes and chromosomes, genome structure (plant, animal, human) transcription (prokaryotes, eukaryotes), translation, regulation of gene expression Chromosomal basis of heredity, Mendelian inheritance, polygenic inheritance Cancer Immune system Microorganisms as tools for research and industry Laboratorijske vaje: Karakterizacijske in separacijske metode v mikrobiologiji Izolacija in analiza bakterijske DNA, RNA in proteinov Laboratory work: Characterization and separation methods in microbiology Isolation of bacterial DNA, RNA and proteins Temeljni literatura in viri / Textbooks: Madigan, T.M., Martinko, J.M., Parker, J.: Brock Biology of Microorganisms, 11th Ed., Prentice Hall, Inc., New Jersey, 2006. Voet, Donald: Fundamentals of biochemistry: life at the molecular level, 2nd ed., J. Wiley & sons, Hoboken (New Jersey), 2006. Dodatna priporočena literatura: Nelson D. L., Cox M. M.; Lehninger Principles of Biochemistry, 4th ed, W.H. Freeman and Company, New York, 2004. Strachan T., Read A. P.: Human Molecular genetics, Gerland Publish, Inc., New York, 3rd ed., 2004. Lodish H., Baltimore D., Berk A., Zipursky S.L., Matsudaira P., Darnell J.: Molecular Cell Biology, 6th Ed., Scientific American Books, Freeman and Co., New York, 2008. Cilji in kompetence: Študenti bodo razumeli strukturne značilnosti in lastnosti glavnih skupin biomolekul ter njihovo vlogo v metabolizmu in ostalih bioloških procesih. Objectives and competences: Students will understand structural characteristics of major groups of biomolecules and their role in cell metabolism and other important biological processes. Predvideni študijski rezultati: Znanje in razumevanje: Študenti bodo razumeli strukturne značilnosti in lastnosti glavnih skupin biomolekul ter njihovo vlogo v metabolizmu in ostalih bioloških procesih: zakonitosti prenosa genetske informacije med generacijami povezave med genotipom in fenotipom Intended learning outcomes: Knowledge and Understanding: Students will understand structural characteristics and properties of main groups of biomolecules, and their role in the methabolism and other biological processes: principles of heredity and transfer of genetic information between generations correlations genotype-phenotype Prenesljive/ključne spretnosti in drugi atributi: pristopi in orodja statistične genetike Transferable/Key Skills and other attributes: approaches and program tools for statistical genetics 104 Metode poučevanja in učenja: predavanja seminarske vaje laboratorijske vaje Načini ocenjevanja: Izpit je opravljen, če so pozitivno opravljene vse naslednje obveznosti: pisni izpit ustni izpit Learning and teaching methods: Lectures Tutorial Laboratory work Delež (v %) / Weight (in %) 60 40 Assessment: Student has to pass successfully the following obligations: written examination oral exemination Reference nosilca / Lecturer’s references: JOSTINS, Luke, MITROVIČ, Mitja, POTOČNIK, Uroš, et al. Host-microbe interactions have shaped the genetic architecture of inflammatorybowel disease. Nature, ISSN 0028-0836, 2012, vol. 491, no. 7422, str. 119-124, doi: 10.1038/nature11582. [COBISS.SI-ID 512230968] REPNIK, Katja, POTOČNIK, Uroš. Haplotype in the IBD5 region is associated with refractory Crohn's disease in Slovenian patients and modulates expression of the SLC22A5 gene. Journal of gastroenterology, ISSN 0944-1174, 2011, vol. 46, no. 9, str. 1081-1091, doi: 10.1007/s00535-011-0426-6. [COBISS.SI-ID 15110422] PERIN, Petra, POTOČNIK, Uroš. Polymorphisms in recent GWA identified asthma genes CA10, SGK493, and CTNNA3 are associated with disease severity and treatment response in childhood asthma. Immunogenetics, ISSN 00937711, 2014, vol. 66, issue 3, str. 143-151, doi: 10.1007/s00251-013-0755-0. [COBISS.SI-ID 17472790] LEITGEB, Maja, ČOLNIK, Maja, PRIMOŽIČ, Mateja, ZALAR, Polona, GUNDE-CIMERMAN, Nina, KNEZ, Željko. Activity of cellulase and [alpha]-amylase from Hortaea werneckii after cell treatment with supercritical carbon dioxide. The Journal of supercritical fluids, ISSN 0896-8446. 2013, 78, 143-148, doi: 10.1016/j.supflu.2013.03.029. [COBISS.SIID 16864790] ČOLNIK, Maja, PRIMOŽIČ, Mateja, KNEZ, Željko, LEITGEB, Maja. Use of supercritical carbon dioxide for proteins and alcohol dehydrogenase release from yeast Saccharomyces cerevisiae. The Journal of supercritical fluids, ISSN 08968446. 2012, 65, 11-17, doi: 10.1016/j.supflu.2012.02.018. [COBISS.SI-ID 15901462] KNEZ, Željko, KAVČIČ, Sabina, GUBICZA, László, BÉLAFI-BAKÓ, Katalin, NÉMETH, Gergely, PRIMOŽIČ, Mateja, LEITGEB, Maja. Lipase-catalyzed esterification of lactic acid in supercritical carbon dioxide. The Journal of supercritical fluids, ISSN 0896-8446. 2012, 66, 192-197, doi: 10.1016/j.supflu.2011.11. [COBISS.SI-ID 15598102] ŠULEK, Franja, PÉREZ FERNÁNDEZ, Daniel, KNEZ, Željko, LEITGEB, Maja, SHELDON, Roger A. Immobilization of horseradish peroxidase as crosslinked enzyme aggregates (CLEAs). Process biochemistry, ISSN 1359-5113, 2011, 46 (3), 765-769, doi: 10.1016/j.procbio.2010.12.001. [COBISS.SI-ID 14712598] KAVČIČ, Sabina, KNEZ, Željko, LEITGEB, Maja. Antimicrobial activity of n-butyl lactate obtained via enzymatic esterification of lactic acid with n-butanol in supercritical trifluoromethane. The Journal of supercritical fluids, ISSN 0896-8446. 2014, 85, 143-150, doi: 10.1016/j.supflu.2013.11.003. [COBISS.SI-ID 17392406] 105 Industrijski projekt Predmet: Course title: UČNI NAČRT PREDMETA / COURSE SYLLABUS Industrijski projekt Industrial Project Študijski program in stopnja Study programme and level Kemijska tehnika / 2. stopnja Chemical Engineering / 2nd level Študijska smer Study field Letnik Academic year 2. Vrsta predmeta / Course type: Semester Semester letni Spring Obvezni / Obligatory Univerzitetna koda predmeta / University course code: Predavanja Lectures Seminar Seminar Nosilec predmeta / Lecturer: Jeziki / Languages: Sem. vaje Tutorial Lab. vaje Labor work Teren. vaje Field work Samost. delo Individ. work 150 ECTS 5 Koordinator praks / Coordinator of industrial projects Predavanja / Lecture: Slovenski/Slovene Vaje / Tutorial: Slovenski/Slovene Pogoji za vključitev v delo oz. za opravljanje študijskih obveznosti: Pogojev ni. Prerequisites: Vsebina: Študent izvaja industrijski projekt s polnim delovnim časom v (industrijski) organizaciji s področja kemije, kemijske in biokemijske tehnike ali drugih procesnih panog. Izjemoma lahko študent izvaja industrijski projekt tudi na fakulteti ali inštitutu, če je zaradi narave projekta to primerneje. Študentu sta dodeljena mentor v organizaciji in na Fakulteti za kemijo in kemijsko tehnologijo, ki je praviloma tudi mentor študentovega magistrskega dela. V času izvajanja industrijskega projekta se študent seznani z organiziranostjo, obratovanjem in poslovanjem organizacije. V okviru projekta obravnava specifični problem v organizaciji. Mentor v organizaciji vodi študenta pri izvajanju aktivnosti, ki pripeljejo do uspešnega zaključka projekta. Študent o izvajanju in rezultatih industrijskega projekta napiše poročilo. Content (Syllabus outline): Student works full-time in an (industrial) organization in the field of chemistry, chemical and biochemical engineering or other process related industries. The industrial project could be exceptionally carried out at the Faculty or Institute if this is required by the nature of project work. Two mentors are appointed to student: one in the organization, and the other one at the Faculty of Chemistry and Chemical Engineering, who is, as a rule, mentor of student’s Master Thesis. Student becomes acquainted with the structure, production process and management in the organization. Within the industrial project, student deals with the specific problem in the organization. Mentor in the organization leads student’s activities to the successful finish of the project. Student prepares a written report about the execution and results of the industrial project. None. 106 Temeljni literatura in viri / Textbooks: Specifično literaturo bodo študentom posredovali mentorji. Cilji in kompetence: Namen industrijskega projekta je, da študent: določen čas dela v (industrijski) organizaciji s področja kemijske in biokemijske tehnike ali druge procesne panoge spozna organiziranost, obratovanje in poslovanje neakademske organizacije uporabi teoretično znanje, pridobljeno med študijem, za reševanje konkretnega problema v praksi pridobi specifične spretnosti, ki jih ne more pridobiti na fakulteti Objectives and competences: The aim of the industrial project is to: work for the specified time period in an industrial chemical, biochemical or other process related organization become familiar with the structure as well as with production and management processes in nonacademic organization apply knowledge gained during the study for solving practical problem acquire skills different from the ones taught at the Faculty Predvideni študijski rezultati: Znanje in razumevanje: poznavanje organiziranosti, obratovanja in poslovanja neakademskih organizacij boljše poznavanje zaposlitvenih možnosti po zaključku študija boljše poznavanje in razumevanje nalog in odgovornosti v poklicnem okolju Intended learning outcomes: Knowledge and Understanding: to understand the structure, production and management process in non-academic organization to increase understanding of employment options after graduation to get a better perception of tasks and responsibilities within a professional environment Prenesljive/ključne spretnosti in drugi atributi: prilagajanje obnašanja in ravnanja v različnih poklicnih okoljih širši pogled na položaj organizacije v določeni panogi in globalnem gospodarstvu (konkurenčnost) pridobljene nove spretnosti, ki so potrebne za uspešno izvajanje in zaključek praktičnega projekta Transferable/Key Skills and other attributes: to learn a different way of behavior, suitable for different professional environments to obtain a better view of the position of a company compared to other companies and global economy (competition) to obtain new skills that are necessary to successfully accomplish practical project Metode poučevanja in učenja: samostojno delo konzultacije z mentorjem v organizaciji priprava pisnega poročila Learning and teaching methods: independent work consultations between student and mentor in the organization preparation of written report Delež (v %) / Načini ocenjevanja: Weight (in %) Assessment: Industrijski projekt je zaključen, če so Student has to pass successfully the pozitivno opravljene naslednje obveznosti: following obligations: 100 pisno poročilo industrijskega projekta written report of industrial project Reference nosilca / Lecturer's references: 107 Magistrsko delo Predmet: Course title: UČNI NAČRT PREDMETA / COURSE SYLLABUS Magistrsko delo Master Thesis Študijski program in stopnja Study programme and level Kemijska tehnika / 2. stopnja Chemical Engineering / 2nd level Študijska smer Study field Letnik Academic year 2. Vrsta predmeta / Course type: Semester Semester letni Spring Obvezni / Obligatory Univerzitetna koda predmeta / University course code: Predavanja Lectures Seminar Seminar Sem. vaje Lab. vaje Drugo* Samost. delo Tutorial Labor work Other Individ. work 20 20 730 *Individualne kontaktne ure s profesorjem/Individual contact hours with lecturer Nosilec predmeta / Lecturer: Jeziki / Languages: ECTS 25 Vsi habilitirani visokošolski učitelji / All lecturers holding valid habilitation Predavanja / Lecture: Vaje / Tutorial: slovenski / Slovene Pogoji za vključitev v delo oz. za opravljanje študijskih obveznosti: Prerequisites: Vsebina: Priprava magistrskega dela poteka kot samostojno delo študenta na raziskovalnem projektu s področja kemijske ali biokemijske tehnike. Magistrsko delo je lahko tudi skupni raziskovalni projekt več študentov. Teme projektov za magistrska dela razpišejo mentorji v okviru raziskovalnih laboratorijev Fakultete za kemijo in kemijsko tehnologijo ali jih predlagajo študentje. Študent pridobi soglasje predvidenega mentorja, ki ga usmerja in svetuje pri izvedbi magistrskega dela. Formalni postopek priprave in zagovora magistrskega dela poteka v skladu s Pravilnikom o postopku priprave in zagovora magistrskega dela na študijskem programu 2. stopnje, Univerze v Mariboru. Predvidene aktivnosti študenta pri pripravi in zagovoru magistrskega dela so naslednje: formulacija problema Content (Syllabus outline): The student has to work independently on a research project concerning chemical or biochemical engineering problem. Master thesis can be a common research project of several students. The research topics are issued by the mentors in the research laboratories of the Faculty of Chemistry and Chemical Engineering or could be initiated by students. Consent of mentor is required. Mentor guides the student through the research work of Master Thesis. The formal procedure for Master Thesis preparation and defence is regulated by the “Pravilnik o postopku priprave in zagovora magistrskega dela na študijskem programu 2. stopnje” of the University of Maribor. The preparation and defence of Master Thesis usually include the following activities of student: problem formulation 108 pregled in analiza dosedanjih raziskav in relevantne literature postavitev raziskovalnih hipotez definiranje metod dela časovni načrt izvedbe projekta praktično delo v enem od raziskovalnih laboratorijev fakultete interpretacija in kritična presoja rezultatov priprava pisnega izdelka ustna predstavitev. state-of-the-art in the proposed field of research and survey of the relevant literature definition of research hypotheses definition of research methods time plan of project practical work in one of the Faculty research laboratories interpretation and evaluation of the results written presentation of the work oral presentation of the work. Temeljni literatura in viri / Textbooks: Kravanja Zdravko, Navodila za kvalitetno izvajanje magistrskega dela. Univerza v Mariboru, Fakulteta za kemijo in kemijsko tehnologijo, Maribor, 2014. http://www.fkkt.um.si/sites/default/files/Navodila%20za%20kvalitetno%20magistrsko%20delo_0.pdf Novak Pintarič Zorka, Kravanja Zdravko, Predloga z navodili za pisanje magistrskega dela. Univerza v Mariboru, Fakulteta za kemijo in kemijsko tehnologijo, Maribor, 2015. http://www.fkkt.um.si/sites/default/files/Predloga_MAG_KT-2015.docx Univerza v Mariboru, Pravilnik o postopku priprave in zagovora magistrskega dela na študijskem programu 2. stopnje. Obvestila UM št. XXX-5-2012, Univerza v Mariboru, 2012. http://www.um.si/univerza/dokumentni-center/akti/Strani/podrobnosti.aspx?iddok=150. Dodatna priporočena literatura: Peter Glavič: Navodila za izdelavo diplomskega dela. Univerza v Mariboru, Fakulteta za kemijo in kemijsko tehnologijo, Maribor, 2008. Specifično literaturo bodo študentom posredovali mentorji. Cilji in kompetence: Cilj je, da študent doseže: sposobnost branja in razumevanja mednarodne literature o določenem problemu sposobnost samostojnega raziskovalnorazvojnega dela z namenom reševanja določenega problema sposobnost dela v interdisciplinarni skupini strokovnjakov sposobnost predstavitve rezultatov dela strokovni javnosti v obliki pisnega poročila, predavanja, diskusije. Objectives and competences: The student would be able to: read and understand international literature of a specific topic work independently in a research and development environment in order to solve specific problem work in an interdisciplinary team of experts present the results to a professional audience by means of a a written report, oral presentation and discussion. Predvideni študijski rezultati: Znanje in razumevanje: poglobljeno obvladanje znanj in izrazoslovja s strokovnega področja magistrskega dela poznavanje sistematike, metod in pristopov raziskovalno-razvojnega dela sposobnost identifikacije, formulacije in reševanja problemov s področja kemijske in biokemijske tehnike Intended learning outcomes: Knowledge and Understanding: mastery of knowledge and terminology in the specific professional field of Master Thesis knowledge of systematics, methods and approaches of research and development work, ability of identification, formulation and solution of problems in the field of Chemical and Biochemical Engineering Prenesljive/ključne spretnosti in drugi atributi: sposobnost samostojnega raziskovalnega dela, reševanja strokovnih problemov, kritičnega razmišljanja in razumevanja strokovne literature sposobnost učinkovite komunikacije o strokovni problematiki Transferable/Key Skills and other attributes: ability to independently accomplish the research work, solve the professional problems, understand the literature and to think critically ability to efficiently communicate about 109 sposobnost učinkovite predstavitve in problematics, ability to efficiently present and interpret the results of work. interpretacije rezultatov dela. Metode poučevanja in učenja: konzultacije in diskusije študenta z mentorjem o vsebinskem poteku dela priprava pisnega izdelka in ustne predstavitve Learning and teaching methods: consultations and discussions between student and mentor about the content and progress of the work preparation of written report and oral presentation Delež (v %) / Načini ocenjevanja: Weight (in %) Assessment: Magistrsko delo je zaključeno, če so Student has to pass successfully the pozitivno opravljene naslednje obveznosti: following obligations: magistrsko delo ustni zagovor magistrskega dela 50 50 Reference nosilca / Lecturer's references: 110 master thesis work master thesis oral presentation