APSTA-GE 2995 Biostatistics I
Transcription
APSTA-GE 2995 Biostatistics I
APTSA-GE2995/GPH-GU-2995 Biostatistics I, Fall 2014 Instructor: Email: Phone: Office/Box: Office Hours: Ryan Richard Ruff [email protected] 212.998-9663 250 Park Avenue South, 6th Floor TBD and by appointment TA: TBD Class Meeting Time/Room: Tuesdays, 4:55-6:35, 401 Silver Lab Meeting Time/Room: Tuesdays, 6:45-8:00, TISC LC19 COURSE OVERVIEW This course is cross-listed under APTSA-GE-2995 and GPH-GU-2995. The course sequence is intended for graduate students in public health and epidemiology. It provides both the foundations necessary for Biostatistics II and serves as a stand-alone introductory statistics course. It will concentrate on the interpretation and comprehension of graphical and statistical techniques that are important components of scientific literature. Mathematical ability at the level of high school algebra is required. Data analysis using SPSS is also an important component of the class. There will be SPSS lab sessions covering the topics of data management and statistical analysis. OBJECTIVES At the conclusion of this course the student will be able to: Apply critical evaluation skills to the reading of scientific research presentations as they relate to: sample statistics, simple hypothesis tests, mean comparison and ANOVA. Understand the principles of probability theory as a basis for making statistical decisions. Perform statistical analyses covered in class using the SPSS statistical program. Combine their knowledge of statistical analysis and use of SPSS to perform an analysis of real data to answer scientific hypotheses. Undertake further study of statistics based on the Biostatistics II course. ASPH CORE COMPETENCIES Students should be able to… 1. Describe the roles biostatistics serves in the discipline of public health 2. Describe basic concepts of probability, random variation and commonly used statistical probability distributions 3. Describe preferred methodological alternatives to commonly used statistical methods when assumptions are not met 4. Distinguish among the different measurement scales and the implications for selection of statistical methods to be used based on these distinctions 5. Apply descriptive techniques commonly used to summarize public health data 6. Apply common statistical methods for inference 7. Apply descriptive and inferential methodologies according to the type of study design for answering a particular research question 8. Apply basic informatics techniques with vital statistics and public health records in the description of public health characteristics and in public health research and evaluation 9. Interpret results of statistical analyses found in public health studies 10. Develop written and oral presentations based on statistical analyses for both public health professionals and educated lay audiences ASPH CROSS-CUTTING COMPETENCIES 1. Use information technology to access, evaluate, and interpret public health data (F8) 2. Articulate an achievable mission, set of core values, and vision (H3) 3. Engage in dialogue and learning from others to advance public health goals (H4) 4. Apply biological principles to development and implementation of disease prevention, control, or management programs (I8) 5. Apply evidence-based principles and the scientific knowledge base to critical evaluation and decision-making in public health (J3) 6. Apply the core functions of assessment, policy development, and assurance in the analysis of public health programs and their solutions (J4) TEXTBOOKS Readings will include a course textbook, additional resources, and reference materials. a. Course textbook: Gertsman, Basic Biostatistics: Statistics for Public Health Practice (2014). Jones & Bartlett Learning, 2nd edition b. Additional online readings showing the use of concepts in applied research will be posted c. We also recommend using http://seeingstatistics.com which has many demonstrations of statistical concepts using Java. OTHER NEEDS Software: The statistical software package SPSS will be used intensively in this course. It is highly recommended that you obtain a copy at NYU computer store. You can also access SPSS in most NYU computer labs as well as via the virtual lab at https://vcl.nyu.edu/vpn/index.html Calculator: A basic scientific calculator is needed. iClicker: iClicker will be used as a tool for interactive teaching. A satisfactory iClicker record (90% participation or higher) is required for you to receive a full participation grade. It is your responsibility to bring the iClicker to class. COURSE REQUIREMENTS Homework Ten homework sets will be assigned during the course. A typical homework involves understanding of the statistical concepts, using SPSS to analyze data and interpreting the results, with only minimal manual calculation. Homework assignments are automatically administrated through NYU Classes. Each assignment will be available online for approximately a week. You will need to complete the assignment online and will receive instant feedback upon completion. The homework will become unavailable after its due time. This means it is not possible to turn in late homework. Projects Two projects will be assigned during the course. Both projects consist of the analysis of a public health or a biological data set. The projects are to be typed and should be professional in appearance. Hand written projects will not be graded. The project is to be worked on and written up independently. Plagiarism will result a grade of 0. By plagiarism we mean either using all or any part of other students’ work as your own or allowing others to use all or any part of your own work. Exams There will be both a midterm and final exam. Each will contain both general statistical knowledge questions and a series of statistical analyses with questions relating to the theory used, assumptions made, and interpretation of the statistical data presented. They do NOT emphasize calculations and formulas. Material from both the lectures and from the text may appear on the exam and all exams are cumulative. GRADE DISTRIBUTION Weekly Homework Projects (2) Midterm Cumulative Final Participation SCHEDULE Week 1 (09/02) Week 2 (09/09) Week 3 (09/16) Week 4 (09/23) Week 5 (09/30) Week 6 (10/07) Week 7 (10/14) Week 8 (10/21) Week 9 (10/28) Week 10 (11/04) Week 11 (11/11) Week 12 (11/18) Week 13 (11/25) Week 14 (12/02) Week 15 (12/09) Week 16 (12/16) 10% 30% (15% each) 20% 30% 10% (assessed through iClicker) Overview Data Visualization: Graphs and Tables Central Tendency Variability Statistical Inference: Samples to Population Confidence Intervals of sample estimates Fall Recess Midterm (Project one due) Probability and the Normal Distribution Hypothesis Testing: One Sample Hypothesis Testing: Two Samples One Way Analysis of Variance Nonparametric Statistics Epidemiological Study Design/Analysis Review (Project two due 12/13) Final Exam 75 minutes *The course schedule is tentative and subject to revisions during the course. Reading Assignments (TBA) Week 1 (09/02) Overview Gertsman Chapter 1, 2 Week 2 (09/09) Gertsman Chapter 3 Data Visualization Week 3 (09/16) Central Tendency Gertsman Chapter 4.1, 4.2, 4.3, 4.4 Week 4 (09/23) Variability Gertsman Chapter 4.5, 4.6, 4.7, 4.8 Week 5 (09/20) Gertsman Chapter 5, 8 Statistical Inference: Samples to Population Week 6 (10/07) Gertsman chapter 10 Confidence Intervals of sample estimates Week 9 (10/28) Gertsman chapter 6, 7 Probability and the Normal Distribution Week 10 (11/04) Gertsman chapter 9, 11 Hypothesis Testing: One Sample Week 11 (11/11) Gertsman Chapter 12 Hypothesis Testing: Two Samples Week 13 (11/18) Gertsman Chapter 13 One Way Analysis of Variance Week 14 (11/25) Nonparametric Statistics Readings to be announced Week 15 (12/02) No readings Epidemiological Study Design/Analysis Students With Disabilities Any student attending NYU who needs an accommodation due to a chronic, psychological, visual, mobility and/or learning disability, or is Deaf or Hard of Hearing should register with the Moses Center for Students with Disabilities at 212 998-4980, 726 Broadway, 2nd Floor, http://www.nyu.edu/csd. Information about the Moses Center for Students with Disabilities must appear on the syllabus. If a student presents documentation from the Moses Center suggesting that unique considerations be applied for that student’s optimal learning, please feel free to consult with the Moses Center or Julie Avina, Associate Dean of Student and Alumni Affairs.