Inclusion body disease (IBD) and Cryptosporidiosis in a boid snake

Transcription

Permission granted only for viewing on the SEVPAC website
2 year old male boa constrictor (Boa constrictor)
y Presented to the referring veterinarian with a history of chronic regurgitation of several months duration y Another boid in the collection was being monitored for a recurrent respiratory problem. y A python in the collection showed acute signs of neurologic disease and died after having been unable to right itself
y Formalin‐fixed tissues of the boa were
submitted for histologic evaluation
y Proliferative gastritis, chronic, diffuse, marked, with intralesional protozoa consistent with Cryptosporidium sp. y Eosinophilic intracytoplasmic inclusion bodies, multifocal, severe, in the mucosal epithelium, muscularis and serosal ganglia of the stomach consistent with inclusion body disease
y Cryptosporidium is a protozoal parasite causing a self‐
limiting infection in immunocompetent mammalian hosts y Cryptosporidium serpentis is
the most common pathologic species found in the snake
y Proliferative gastritis in reptile hosts that is fatal
y Typically progresses to an Photo Courtesy of Dr. Scott Terrell
advanced disease state prior to the onset of clinical signs
Normal Boid Stomach
y Ingested oocysts release sporozoites
which invade the brush border of the
gastric mucosal epithelium
y Infection causes a proliferative gastritis, resulting in a decreased
gastric lumen size and severe
mucosal irritation
Proliferative Gastritis
y Affected animals may succumb to acute disease, or may progress along a clinical course of up to two years Photos Courtesy of Dr. Scott Terrell
y Inclusion body disease (IBD) of boid snakes has been recognized since the 1970s y Signs of infection in boas include y Central nervous system disorders
y
y
y
y
Inability to control body movements
Inability to right itself
“Star‐gazing"
Inability to strike or constrict
y Gastrointestinal abnormalities
y Chronic regurgitation
y Extreme weight loss
y Respiratory infections Photo Courtesy of Dr. Elliott Jacobson
y Characteristic intracytoplasmic
inclusion bodies observed in: y
y
y
y
Epidermal cells
Oral mucosal epithelial cells
Visceral epithelial cells
Neurons
Photo Courtesy of Dr. Elliott Jacobson
y The causative agent is currently unknown but lesions have been associated with the presence of a retrovirus
Photo Courtesy of Dr. Elliott Jacobson
y Individually, either disease had the potential to result in chronic regurgitation and anorexia
y Cryptosporidiosis
y Gastric hyperplasia and intralesional protozoa y Proliferative gastritis with a decreased lumen size resulted in chronic regurgitation
y Inclusion Body Disease
y Inclusions within the gastric mucosal epithelium and were found within all tissues evaluated
y Disseminated disease results in neurologic and cellular dysfunction manifesting as chronic regurgitation
y No known treatment of either disease makes these of particular concern with management of collections
y Schumacher, J., Jacobson, E.R.; Homer, B.L.; Gaskin, J.M. 1994. Inclusion y
y
y
y
y
body disease in boid snakes. J. of Zoo and Wildlife Med. 25(4):511‐524.
Douglas Mader, DVM, Reptile Medicine and Surgery second edition (2006) Saunders, Philadelphia PA. Axthelm, M.K. 1985. Viral encephalitis of boid snakes. Int. Colloq. Pathol. Reptiles Amphib. 3:25. (Abstract) IBD.
Xiao, L., et. al 2004. Genetic Diversity of Cryptosporidium spp. in captive reptiles. Applied and Environmental Microbiology. Feb pp.891‐899.
Fayer, R. Niorgan U, and Upjohn SJ. 2000. Epidemiology of Cryptosporidium; transmission, detection and identification. Int.J. Parasitol. 30:1305‐1322.
Brownstein DG, Strandberg RJ, Montail M, Bush and Fortner J. (1977) Cryptosporidium in snakes with hypertrophic gastritis. Vet Pathol. 14:606‐
617.
Special thanks to Dr. Scott Terrell, Dr. Elliott Jacobson and Claire Caruana
for providing photographs for this presentation

Inclusion body disease (IBD) and Cryptosporidiosis in a boid snake

Transcription

Similar documents

Placentitis and Abortion in a Swine

Systemic Exophiala Infection in a Giant Frog Fish (Antennarius

N07-88 Visceral Laminosioptes cysticola in l k h a Palawan Peacock

A Ratty Story - University of Georgia College of Veterinary Medicine

JDJ.ICJm:lf

average screen time spent per person per day in zero tv homes the

SpectraLight® III Color Viewing Booth

UNIVERSAL REMOTE

FAQ - Frequently Asked Ques on`s

Optical Devices on Display, Department of Rare Books and Special

Manning Stainton Info Graphics_ selling your home v3

MACROECONOMICS STUDENT PACKET

10-34 Buy Buy Baby Bonus Sign Area report

Sapphire Community Portal for Parents/Students

PDF - Da-Lite

Classification of gastritis

FREE now! - Eight Martinis – Remote Viewing Magazine

What is gastritis? What is gastropathy? How is it classified?

2013 - The Black Vault