FINAL PROGRAM
Transcription
FINAL PROGRAM
FINAL PROGRAM 18TH INTERNATIONAL CONGRESS ON ANIMAL REPRODUCTION JUNE 26-30TH 2016 LE VINCI IN TOURS FRANCE The cutting edge science… in the garden of France. Reproductive physiology, pathology and biotechnologies in domestic and wild animal species. ADMINISTRATIVE OFFICE www.icar2016.org TABLE OF CONTENTS EDITORIAL P. 3 COMMITTEES MEMBERS P. 4 PROGRAM AT-A-GLANCE P. 6 Sunday June 26 p. 6 th Monday June 27 p. 6 th Tuesday June 28 p. 7 th Wednesday June 29 p. 8 Thursday June 30th p. 9 GENERAL INFORMATION P. 10 PRIZE AND AWARDS P. 11 NETWORKING OPPORTUNITIES P. 12 PROGRAM P. 13 th Sunday June 26 p. 13 Monday June 27th p. 13 Tuesday June 28th p. 19 Wednesday June 29th p. 26 Thursday June 30th p. 35 SPONSORS P. 36 EXHIBITOR FLOOR PLAN P. 38 th 2 EDITORIAL Cutting edge science… Beyond the recent developments of reproductive physiology studies and biotechnologies in farmed and wild species, this edition of ICAR will bring up several emerging topics and concepts, including predictive biology, epigenetic regulations, developmental origin of adult health and new insights in neuroendocrinology. Gathering outstanding speakers in the different fields of reproduction research, from basic knowledge acquisition to field application, this conference will provide high quality scientific contents to any attendee. … In the garden of France Located in the centre of France, the Loire Valley is a road to history. The majestic Loire river flows peacefully in a bucolic environment punctuated by precious traces of the past. Amongst them, the castles from the Renaissance period (Chambord, Chenonceau,…) became the obvious symbol of this region. Architectural treasures legated from the past, they also bear the history of France and its Kings. Region of traditions, the Loire Valley is a conservatory of French way of life with delicate and tasteful gastronomy and worldwide known wines. All these treasures will be at easy reach to the ICAR participants during the meeting itself and during post conference tours. 3 COMMITTEES MEMBERS LOCAL COMMITTEE 4 ALMINANA Carmen BELTRAMO Massimiliano BRIVOIS Jean-Pierre CHAVATTE-PALMER Pascale CHEMINEAU Philippe CORBIN Emilie CORDEIRO Luiz DRUART Xavier DUITTOZ Anne GUILLOU Florian MAGALLON Thierry MERMILLOD Pascal PINAULT Marie-Françoise REYNAUD Karine SALVETTI Pascal VAUDIN Pascal WOJTENKA Jacky SCIENTIFIC COMMITTEE BO Gabriel BALL Barry BARUSELLI Pietro BAUERSACHS Stefan CABALLERO POSADAS Ignacio CHAVATTE-PALMER Pascale COY Pilar DARDENTE Hugues DE SOUZA-FABJAN Joanna DISKIN Michael DRUART Xavier DUITTOZ Anne FIENI Francis FIGUEIREDO Ricardo JOLY Thierry KEELEY Tamara LUCY Matthew MERMILLOD Pascal MOURIER Eve NAGAI Takashi REITER Eric REYNAUD Karine SALAMONE Daniel SANDRA Olivier SARTORI Roberto SIRARD Marc André SKIDMORE Lulu SUDANO Mateus TARRADE Anne TESFAYE Dawit THOMPSON Jeremy UZBEKOVA Svetlana VAN SOOM Ann VAUDIN Pascal WILLIAMS John WOLF Eckhard 5 PROGRAM AT-A-GLANCE SUNDAY JUNE 26TH 2016 TIME AUDITORIUM FRANCOIS Ier AUDITORIUM PIERRE DE RONSARD AUDITORIUM DESCARTES ROOM DIANE DE POITIERS 4.00 pm - 7.00 pm Welcome desk opening 7.00 pm - 9.00 pm Get together party Salle des fêtes, Tours City Hall ROOM CATHERINE DE MEDICIS ROOM COURTELINE ROOM CATHERINE DE MEDICIS ROOM COURTELINE Workshop Transgenesis technologies and stem cells Workshop 6 MicroRNA in gametes and embryos MONDAY JUNE 27TH 2016 TIME 8.00 am - 9.30 am 9.30 am - 10.30 am AUDITORIUM FRANCOIS Ier AUDITORIUM PIERRE DE RONSARD ROOM DIANE DE POITIERS Opening ceremony Simmet prize Plenary: Toward an integrative and predictive biology of reproduction 10.30 am - 11.00 am 11.00 am to 12.30 pm AUDITORIUM DESCARTES Coffee break on the exhibition area Workshop Cryobiology of gametes and embryos Workshop Oocyte quality 12.30 pm - 1.30 pm Workshop Canine and feline reproduction Workshop Seasonality of reproduction and its control Lunch on the exhibition area Symposium Sheep and goat reproduction Symposium Pig reproduction Symposium Horse reproduction Symposium Buffalo reproduction 1.30 pm to 4.00 pm 4.00 pm - 4.30 pm Coffee break on the exhibition area 4.30 pm - 5.30 pm Poster sessions 5.30 pm - 7.00 pm 7.00 pm to 11.00 pm 6 French Underground Party Caves de la Croix Douillard (Amboise) IETS Workshop Main goal of research into the safe and sanitary collection and transfer of embryos of livestock TUESDAY JUNE 28TH 2016 AUDITORIUM PIERRE DE RONSARD TIME AUDITORIUM FRANCOIS Ier 8.30 am to 10.30 am Plenary Metabolism and reproduction AUDITORIUM DESCARTES 10.30 am to 11.00 am 11.00 am to 12.30 pm 5.30 pm - 7.00 pm Workshop Spermatology Workshop Embryo technologies Workshop Camelids reproduction Symposium Reproductive parameters of high yielding dairy cattle Symposium Reproductive management in beef cattle production systems Workshop Reproductive pathologies 12.45 pm to 1.30 pm IMV workshop Semen analysis: a new perspective to improve fertility Lunch on the exhibition area 4.00 pm - 4.30 pm 4.30 pm to 5.30 pm ROOM CATHERINE DE MEDICIS ROOM COURTELINE Workshop Wild animal reproduction Workshop Endocrine perturbators Coffee break on the exhibition area 12.30 pm - 1.30 pm 1.30 pm to 4.00 pm ROOM DIANE DE POITIERS Symposium Neuroendocrine control of reproductive function Symposium Placental function Lunch on the exhibition area COST SALAAM Workshop: Recent developments in gene editing, phenotyping, and biobanking of large biomedical models Coffee break on the exhibition area Student competition Poster sessions 7 WEDNESDAY JUNE 29TH 2016 TIME AUDITORIUM FRANCOIS Ier 8.30 am to 10.30 am Plenary Somatic environment and oocyte differentiation AUDITORIUM PIERRE DE RONSARD 10.30 am - 11.00 am 11.00 am to 12.30 pm ROOM DIANE DE POITIERS Workshop Estrus cycle control and insemination Workshop Ultrasonography and other imaging methods Workshop Embryo implantation Workshop Embryo metabolism Lunch on the exhibition area Symposium Early maternal - embryo communication Symposium Genomics of the reproductive function Symposium Ovarian cortex and follicles culture Symposium Biomedical applications of transgenesis 4.00 pm - 4.30 pm Coffee break on the exhibition area 4.30 pm - 5.30 pm Poster sessions 5.00 pm - 7.30 pm 8.00 pm - 12.00 am 8 ROOM CATHERINE DE MEDICIS ROOM COURTELINE Workshop Evolution of omic tools and integration of omic data Workshop Strategies for identification and conservation of genetic diversity 12.45 pm to 1.30 pm IMV workshop Boar semen: innovative and safe production process Lunch on the exhibition area Coffee break on the exhibition area 12.30 pm - 1.30 pm 1.30 pm - 4.00 pm AUDITORIUM DESCARTES Gala Diner Grange de Meslay THURSDAY JUNE 30TH 2016 TIME AUDITORIUM FRANCOIS Ier 8.30 am - 10.30 am Plenary Epigenetic control in gametes and embryos 10.30 am - 11.00 am 11.00 am - 1.00 pm AUDITORIUM PIERRE DE RONSARD AUDITORIUM DESCARTES ROOM DIANE DE POITIERS ROOM CATHERINE DE MEDICIS ROOM COURTELINE Coffee break on the exhibition area Plenary Developmental origin of adult animal health and animal production CLOSING CEREMONY 1.00 pm - 1.30 pm End of the congress 9 GENERAL INFORMATION Registration Desk The registration desk is located on the main entrance of Le Vinci and will be open at the following times: Sunday, June 26 Monday, June 27 Tuesday, June 28 Wednesday, June 29 Thursday, June 30 4.00 pm to 7:00 pm 7.15 am to 6:30 pm 8.00 am to 6:30 pm 8.00 am to 6:30 pm 8.00 am to 11.00 am Name Badge Policy Name badges have been sent by email to all delegates. But they can be provided to all delegates and participants when they check-in at the ICAR 2016 Registration Desk. It is your admission pass to the scientific sessions, the exhibit hall and social events. Delegates are required to wear their name badge at all times and will not be granted access to the Congress without it. Please wear your name badge at all times. This is to ensure that access to the Congress is properly managed. Dress Code Casual business attire is recommended for the Congress. Preview Room The preview room is located in the 2nd floor of Le Vinci. An audio-visual technician will be available to assist with your presentation. Due to the large number of presentations scheduled throughout the Congress, speakers are asked to visit the preview room the day before their presentation. The preview room will be open to assist you at the following times: Monday, June 27 Tuesday, June 28 Wednesday, June 29 Thursday, June 30 7.00 am to 5:00 pm 8.00 am to 5:00 pm 8.00 am to 5:00 pm 8.00 am to 12.00 pm Poster Presentations Posters are displayed on the exhibition area. Poster presentations are scheduled according the following schedules: Monday, June 27 4.30 pm to 5.30 pm Tuesday, June 28 5.30 pm to 7.00 pm Wednesday, June 29 4.30 pm to 5.30 pm Authors are required to be present during their specific session. Certificate of attendance ICAR 2016 will provide certificate of attendance on site upon request, and then it will be sent to all participants by email, one week after the congress. ICAR 2016 Congress Secretariat Email: [email protected] 10 PRIZE AND AWARDS Simmet prize The Simmet Prize is sponsored by Minitube International and administered by the International Congress on Animal Reproduction (ICAR). The award, established as a memorial to the accomplishments of Dr. Ludwig Simmet, recognizes an active research scientist for outstanding basic and applied research published during the previous six years in the area of assisted reproduction of animals. Scientists at all phases of their career (early, mid- and late) are considered. The Simmet Prize, which is presented every four years at ICAR, includes an award of 50,000 euros. The Awards Committee consider the significance of research areas under investigation, the breadth and depth of the research platform, the degree of originality of the research as documented in the publications, and potential impact of the research contributions on animal reproduction. Professor Katrin Hinrichs, of Texas A&M University, College Station, Texas, is the recipient of the 2016 Simmet Prize for Assisted Reproduction. The prize, which is the most prestigious award in animal reproduction and one of the largest of its kind, was awarded based on the pioneering efforts of Dr. Hinrichs to elucidate the fundamental biology of gametes and embryos in the horse and to develop laboratory techniques that have made assisted reproduction technologies in the horse a practical reality. The clinical program in equine assisted reproduction she founded in 2009 in collaboration with the Section of Theriogenology at Texas A&M is now one of the largest in the world and has performed over 450 embryo production procedures in 2015 alone. Dr. Hinrichs holds the Patsy Link Chair in Mare Reproductive Studies and has joint appointments in the Department of Veterinary Physiology and Pharmacology and the Department of Large Animal Clinical Sciences, College of Veterinary Medicine & Biomedical Sciences, Texas A & M. She and her colleagues have been instrumental in the development of assisted reproductive techniques in the horse. Areas in which Dr. Hinrichs and colleagues have made instrumental advances include in vitro maturation of eggs, fertilization by intra-cytoplasmic sperm injection, embryo culture, cloning, cryopreservation of embryos and the use of embryonic biopsy to enable pre-implantation genetic screening. Travel grants Over 40 applications were received for the Travel Grant. We thank each and every one of our applicants. The Awards Committee had a very difficult task of selecting the 13 award recipients out of such a large pool of worthy applicants. Congratulations to the award recipients: Mario Balaro Eileen Cofré Narbona Panahi Farnaz Meriem Fatnassi Arman Hosseini Heba Hozyen Ali Husnain Maryam Javed Lucia Moro Kelly Roballo Monika Saini Rodrigo Silva Nunes Barreto Solange Sousa Student competition Five finalists have been selected by the jury amongst 104 applications. They will give a short presentation of their work during a plenary session, and will be ranked by the jury on the basis of abstract, poster and oral presentation. Each of these five finalists will receive a prize and a diploma at the closing ceremony. The jury is composed of five outstanding scientists: Philippe Chemineau (President), Simon de Graaf, Peter Hansen, Patrick Lonergan, and Ann Van Soom. 11 NETWORKING OPPORTUNITIES Get together Party Sunday June 26th 7.00 pm to 9.00 pm Location: Mairie de Tours – Salle des Fêtes - Rue des Minimes, 37000 Tours Dress code: casual The ICAR 2016 local committee invites you to start the congress by sharing a drink at Tours City Hall. It will be the opportunity to meet colleagues, network, exhibitors and catch up with old acquaintances! Admission to the get together party is included for registered delegates and registered accompanying persons. French underground Party Monday June 27th 7.00 pm to 11.00 pm Location: Les Caves de la Croix Douillard - 510 Quai des Violettes, 37400 Amboise Dress code: casual You will enjoy a dinner cocktail in an ancient cellar under the rocks. Buses will leave Le Vinci in order to transport you directly there (departure: 6.30 pm and 6.45 pm). Buses will leave then to go back to Le Vinci (departure: 11.00 pm and 11.15 pm). Tickets must have been purchased at Registration (no tickets for sale on-site). Gala dinner Wednesday June 29th 8.00 pm to 0.00 am Location: La Grange de Meslay - Rue de Meslay, 37210 Parçay-Meslay Dress code: Smart Business/Cocktail Join us in the most ancient fortified farms of the XIIIth century, with its outbuildings, in the center of which stands the Grange de Meslay, a medieval barn of 1.500m. The Grange de Meslay is an important agricultural domain of the Abbey of Marmoutier (9th-18th centuries). It is undoubtedly the most remarkable example remaining in France and even in Europe of monastic buildings constructed for agricultural use. Accompanied by other buildings, it was originally situated in a vast enclosure of almost two hectares, surrounded by walls, whose vestiges clearly show their original outline. You will enjoy your last night in Tours in this beautiful place and you will have a taste of French gastronomy. Buses will leave Le Vinci in order to transport you directly there (departure: rotation between 7.00 pm and 7.45 pm). Buses will leave then to go back to Le Vinci (departure: rotation between 0.00 am and 0.45 am). Tickets must have been purchased at Registration (no tickets for sale on-site). 12 PROGRAM SUNDAY JUNE 26TH 4.00 pm to 7.00 pm Welcome desk opening at Le Vinci 7.00 pm to 9.00 pmGet together party Tours City Hall MONDAY JUNE 27TH 8.00 am - 10.30 am OPENING CEREMONY 8.00 am - 8.10 am Renaissance music and dance exhibition AUDITORIUM FRANCOIS Ier 8.10 am - 8.15 amInauguration speech Pascale Chavatte-Palmer (France) and Pascal Mermillod (France) 8.15 am - 8.20 amIntroduction Philippe Chemineau (France) 8.20 am - 8.35 amScience and society François Houllier, President of INRA (France) 8.35 am - 8.45 amICAR history and introduction of Simmet Prize Peter Hansen, President of ICAR (USA) 8.45 am - 8.50 am Simmet Prize attribution Christian Simmet (Minitube International's CEO, Germany) 8.50 am - 9.30 amSimmet prize lecture: A journey through people, places, and projects in equine assisted reproduction Katrin Hinrichs (USA) 9.30 am - 10.30 amPlenary: Toward an integrative and predictive biology of reproduction AUDITORIUM FRANCOIS Ier Chairs: Eric Reiter (France) and Stéphane Fabre (France) •M utiscale modelling of the hypothalamo-hypophyso-gonadal axis Frédérique Clément (France) •C omputational modeling approaches in gonadotropin signaling Anne Poupon (France) 10.30 am - 11.00 am Coffee break on the exhibition area 11.00 am - 12.30 pmWorkshop: Cryobiology of gametes and embryos AUDITORIUM FRANCOIS Ier Chairs: Mateus Sudano (Brazil) and Joanna De Souza-Fabjan (Brazil) 11.00 am - 11.30 amEmbryo lipids and cryobiology Mateus Sudano (Brazil) 11.30 am - 11.45 amW11 - The effects of vitrification at the germinal vesicle stage on transzonal projections and cumulus expansion in porcine cumulus-oocyte complexes Ruth Appeltant (Japan) 11.45 am - 12.00 pmW12 - Pregnancy after transfer of in vitro produced equine embryos derived from vitrified immature oocytes Nerea Ortiz-Escribano (Belgium) 12.00 pm - 12.15 pmW14 - Easy technique to cryopreserve welsh pony embryo Florence Guignot (France) 12.15 pm - 12.30 pmW13 - Vitrification with the minimum volume Cryotop method improves embryo survival and birth rate of both in vivo and in vitro produced ovine embryos Pedro dos Santos Neto (Uruguay) 13 MONDAY JUNE 27TH AUDITORIUM DESCARTES 11.00 am - 12.30 pmWorkshop: Canine and feline reproduction Chairs: Karine Reynaud and Wenche Kristin Farstad (Norway) 11.00 am - 11.15 amW21 - Sperm effects of Benign Prostatic Hyperplasia and on prostatic and testicular hemodynamic features in dogs. Daniel Angrimani (Brazil) 11.15 am - 11.30 amW22 - Expression of luteinizing hormone receptor messenger RNA by canine ovarian follicles during the estrous cycle. Monica de los Reyes (Chile) 11.30 am - 11.45 amW23 - Expression of leukocyte activation markers is higher in pregnant than in nonpregnant bitches Bodil S Holst (Sweden) 11.45 am - 12.00 pmW24 - Early embryo development and plasma progesterone profiles in dogs Rita Payan-Carreira (Portugal) 12.00 pm - 12.15 pmW25 - Pluripotent stem cells in domestic carnivores (Canis familiaris and Felis catus) placentae Kelly Roballo (Brazil) 12.15 pm - 12.30 pmW26 - Corpus luteum volume and serum progesterone concentrations in the bitch María Cecilia Stornelli (Argentina) 11.00 am - 12.30 pmWorkshop: Transgenesis and stem cells ROOM CATHERINE DE MEDICIS Chairs: Ignacio Caballero Posadas (France) and Hiroshi Nagashima (Japan) 11.00 am - 11.15 amW31 - Characteristics of prion gene knockout Japanese Black caws produced to prevent spontaneous bovine spongiform encephalopathy infection Noboru Manabe (Japan) 11.15 am - 11.30 amW32 - OCT4 (POU5F1) has no influence on the ratio of inner cell mass to trophectodermal cells in cloned bovine day 7 blastocysts Kilian Simmet (Germany) 11.30 am - 11.45 amW33 - Mutation efficiency and developmental outcome after CRISPR/Cas9 microinjection in sheep oocytes and zygotes Marcela Vilariño (USA) 11.45 am - 12.00 pmW34 - Evidence of mesenchymal stem cells survival after transplantation into the muscle layer of uterine cervix in swine. Michal Dabrowski (Poland) 12.00 pm - 12.15 pmW35 - Epigenetic states of chicken fibroblasts are changed during reprogramming processes by pH in culture Narae Kim (Japan) 12.15 pm – 12.30 pmPW325 - Generation of IL2RG knockout pigs using CRISPR/Cas9 system Kwang-Wook Park (South Korea) 11.00 am - 12.30 pmWorkshop: Seasonality of reproduction and its control ROOM DIANE DE POITIERS Chairs: Hugues Dardente (France) and José Delgadillo (Mexico) 11.00 am - 11.15 amW41 - Effect of Dietary Fatty Acids on Embryo Development, Endocrine Status and Milk Yield of Lactating Holstein Cows during Two Seasons Yusuf Ziya Guzey (Turkey) 11.15 am - 11.30 amW42 - Summer induces DNA damage in boar sperm: Implications for the management of seasonal infertility. Damien Paris (Australia) 11.30 am - 11.45 amW43 - Seasonal effects on sperm quality of Holstein dairy bulls in Spain Maria Sabés-Alsina (Spain) 14 MONDAY JUNE 27TH 11.45 am - 12.00 pmW44 - Challenging the ‘KNDy hypothesis’: The effects of nutrition on GnRH production. Stacey Rietema (Australia) 12.00 pm - 12.15 pmW45 - Induction of fertile ovulation and puberty advancement by a new kisspeptin analog Caroline Decourt (France) 12.15 pm - 12.30 pmW46 - Effects of an early exposure to sexually active bucks on the age at puberty and sexual behavior of goats Manon Chasles (France) 11.00 am - 12.30 pmWorkshop: Oocyte quality AUDITORIUM PIERRE DE RONSARD Chairs: Marc André Sirard (Canada) and Rozenn Dalbies-Tran (France) 11.00 am - 11.13 amW51 - Beneficial effect of low dose docosahexaenoic acid during IVM on oocyte developmental potential and impact on cumulus cell transcriptome in cattle Mouhamad Oseikria (France) 11.15 am - 11.28 amW52 - Melatonin synthesized by mitochondria to improve oocyte’s quality under in vitro conditions. Changjiu He (China) 11.30 am - 11.43 am W53 - Palmitic acid induces mitochondrial protein acetylation and inhibits mitochondrial function in porcine oocytes Itami Nobuhiko (Japan) 11.45 am - 11.58 amW54 - Porcine fertilization coincides with immediate coating of cytosolic p62 and LC3B from the oocyte to entering sperm mitochondria and mitophagic degradation. Bart Gadella (The Netherlands) 12.00 pm - 12.13 pmW55 - Natriuretic peptide receptor 2 (NPR2) localized in bovine oocyte membranes underlies a novel and unique mechanism for C-type natriuretic peptide (CNP)induced meiotic arrest An Lei (China) 12.15 pm - 12.28 pmW56 - Alpha-linoleic acid enhances mitochondrial activity in cumulus cells and improves developmental capacity of bovine oocytes matured under lipotoxic conditions Waleed F.A. Marei (Belgium) 11.00 am - 12.30 pmWorkshop: MicroRNA in gametes and embryos ROOM COURTELINE Chairs: Dawit Tesfaye (Germany) and Michael Hoelker (Germany) 11.00 am - 11.10 amW61 - Examination the stem cell specific microRNA-s in rabbit blastocysts and pluripotent stem cells Elen Gócza (Hungary) 11.10 am - 11.20 amW62 - PIWIs and piRNAs in Retrotransposon Defense and mRNA Targeting in the Early Bovine Embryo Jonathan LaMarre (Canada) 11.20 am - 11.30 amW63 - Differential expression of microRNAs throughout gestation in the mare Shavahn Loux (United States) 11.30 am - 11.40 amW64 - Paternal effect on the miRNA content of bovine blastocysts Rolando Pasquariello (Italy) 11.40 am - 11.50 amW65 - Characterization of miRNAs and piRNAs in the Seminal Plasma of Beef Bulls with Predicted High and Low Fertility Stephanie Perkins (USA) 11.50 am - 12.00 pmW66 - Small non coding RNA from frozen bull sperm cells Eli Sellem (France) 15 MONDAY JUNE 27TH 12.00 pm - 12.10 pmW67 - Functional evaluation of miRNAs during the follicle-luteal transition in the monovular ovary: a potential involvement of miR-132 and miR-96 in cell survival Bushra T. Mohammed (United Kingdom) 12.10 pm - 12.20 pmW68 - Do microRNAs mediate supportive role in maintenance of the luteal function? Emilia Przygrodzka (Poland) 12.30 pm - 1.30 pm Lunch on the exhibition area AUDITORIUM FRANCOIS Ier 1.30 pm - 4.00 pmSymposium: Sheep and goat reproduction Chairs: Joanna De Souza-Fabjan (Brazil) and Rodolfo Ungerfeld (Uruguay) ntrinsic determinants and predictors of superovulatory yields in sheep: • I Circulating concentrations of reproductive hormones, ovarian status and antral follicular blood flow Pawel Bartlewski (Canada) Non-Surgical Embryo Recovery and Transfer in Sheep and Goats • Jeferson Fonseca (Brazil) • Recent advances in in vitro embryo production in small ruminants Teresa Paramio (Spain New insights and current tools for genetically engineered (GE) sheep and goats • Alejo Menchaca (Uruguay) 1.30 pm - 4.00 pmSymposium: Pig reproduction AUDITORIUM PIERRE DE RONSARD Chair: Takashi Nagai (Taiwan) • C ontribution of in vitro systems to preservation and utilization of porcine genetic resources Kazuhiro Kikuchi (Japan) Derivation of porcine pluripotent stem cells for biomedical research • Lih-Ren Chen (Taiwan) The ubiquitious hyaluronan: functionally implicated in the oviduct • Manuel Alvarez-Rodriguez (Sweden) Will artificial insemination in pigs become more efficient? • Alfonso Bolarin (Spain) S21 - Repetitive interactions between STIM1 and ORAI1 at fertilization in pig • oocytes Lu Zhang (USA) S22 - Glutamate increases fertilizing ability of boar sperm. • Diego Bucci (Italy) 1.30 pm - 4.00 pmSymposium: Buffalo reproduction Chair: Pietro Baruselli (Brazil) • N ew Strategies to Enhance Buffalo Reproduction Nasim Ahmad (Pakistan) 16 ROOM DIANE DE POITIERS MONDAY JUNE 27TH • S trategies to overcome seasonal anestrus in water buffalo Nelcio Carvalho (Brazil) Embryonic and foetal mortality in River buffalo (Bubalus bubalis) • Giuseppe Campanile (Italy) Vitrification of buffalo oocytes and embryos • Rangsun Parnpai (Thailand) S31 - Pregnancy-associated glycoprotein (PAG) profile in water buffaloes (Bubalus • bubalis) throughout pregnancy and postpartum periods utilizing homologous antisera Vittoria Lucia Barile (Italy) S32 - Concentration of AMH in relation to concentrations of steroids and mRNA • expression of INHA and AMH in buffalo antral follicles Aixin Liang (China) 1.30 pm - 4.00 pmSymposium: Horse reproduction AUDITORIUM DESCARTES Chair: Barry Ball (USA) mbryo-maternal communication during the first four weeks of equine pregnancy • E Tom Stout (The Netherland) Steroids in the establishment and maintenance of pregnancy, and at parturition in • the mare Alan Conley (USA) New flow cytometry approaches in equine andrology • Fernando Peña (Spain) Tissue invasion mechanisms of the chorionic girdle • Dough Antczak (USA) 1.30 pm - 4.00 pmIETS Workshop: Do we need research for safe trading of embryo and semen? ROOM CATHERINE DE MEDICIS 1:30 pm - 1:45 pm Introduction IETS Christine Wrenzycki (IETS Board President – Germany) 1:45 pm - 2:15 pm Which research information do you expect: Survey analyze. Contents: Presentation of the survey analyze. The main results. Francis Fieni (Chair IETS HASAC committee – France) 2:15 pm - 2:45 pm Gap between scientific knowledge and regulatory mesures for trade of embryos and semen: General policy – no standards without scientific information Jae Myong Lee (OIE representative - South Korea) 2:45 pm - 3:45 pm Round table: Which priority by continent to facilitate the germ plasm trade. Chairs: Jan Venneman (Director of EFFAB European Forum of Farm Animal Breeders – Belgium) 3:45 pm - 4:00 pm Conclusion 4.00 pm - 4.30 pm Coffee break on the exhibition area 4.30 pm - 5.30 pm Poster sessions on the exhibition area 7.00 pm - 11.00 pm French Underground Party (Caves de la Croix Douillard) Christine Wrenzycki (Germany), Fulvio Gandolfi (Italy) and Francis Fieni (France) 17 THE MICHELSON PRIZE AND GRANTS Encouraging and incentivizing scientists to make what would be the single biggest breakthrough in the fight against animal overpopulation. UP TO $750,000 Qualifying scientists will have an innovative approach pursuant of the first single-dose, permanent, nonsurgical sterilization method for male and female dogs and cats. Proposed research doesn’t need to meet PER GRANT all the criteria for the Michelson Prize, but it would FOR THE PURSUIT OF NEW STERILIZATION TECHNOLOGY submit “proof of concept” studies in cell culture or THE definitely help your chances. We encourage you to rodents (in certain cases), and/or in dogs and cats. $25 MILLION PRIZE As much as we want to give away this $25 million, there are some criteria that need to be met... > The winning entry must be a single-dose, > There will be a viable pathway for > It will be safe and effective for cats and dogs, > It will be suitable for use in a field setting. > The manufacturing process and cost permanent, nonsurgical sterilant. both male and female. > It will ablate sex steroids and/or their effects. regulatory approval. will be reasonable. For more information, visit: MICHEL SONPRIZE ANDG R ANT S .ORG The Michelson Prize & Grants is open to any entity and all well-qualified individuals or groups. Scientists from a diverse range of fields are encouraged to apply. TUESDAY JUNE 28TH 8.30 am - 10.30 amPlenary: Metabolism and reproduction Chair: Matthew Lucy (USA) AUDITORIUM FRANCOIS Ier • Metabolic and endocrine differences between Bos taurus and Bos indicus females that impact the interaction of nutrition with reproduction Roberto Sartori (Brazil) P21 - Non-esterified fatty acids influence progesterone production in feed • restricted dairy heifers Peter Vos (The Netherlands) P22 - Lactate induces a luteal-like transformation of cultured bovine granulosa • cells that is dependent upon lactate transport into the cells as well as on the intracellular PKA signaling pathway Anja Baufeld (Germany) P23 - Expression of adipokines and several lipid metabolism actors in adipose • tissues and granulosa cells during lactation in dairy cows Namya Mellouk (France) P24 - Influence of Energy Balance on plasma LH secretion in postpartum Holstein • dairy cows: importance of plasma adiponectin secretion level? Joëlle Dupont (France) P25 - Effect of non-esterified fatty acids on the viability of bovine endometrial • epithelial cells Wiruntita Chankeaw (Sweden) P26 - Effects of undernutrition and the presence of an embryo upon endometrium • transcriptome in sheep Victoria de Brun (Uruguay) 10.30 am - 11.00 am Coffee break on the exhibition area 11.00 am - 12.30 pmWorkshop: Embryo technologies AUDITORIUM FRANCOIS Ier Chairs: Daniel Salamone 11.00 am - 11.15 amW121 - Identification of extracellular vesicle secreted by bovine blastocysts Rodriguez-Alvarez Lleretny (Chile) 11.15 am - 11.30 amW122 - Effecto of bovine oviduct and uterine fluids on in vitro embryo development and quality Meriem Hamdi (Spain) 11.30 am - 11.45 amW123 - Time-Lapse Image Analysis of Equine Pre-Implantation Embryo Development to the Blastocyst Stage Shawn Chavez (USA) 11.45 am - 12.00 pmW124 - Embryo selection system using the kinetics of early embryo development in bovine embryos produced in vitro and pregnancy outcome Kei Imai (Japan) 12.00 pm - 12.15 pmW125 - Plasma anti-Mullerian hormone as a predictive marker of juvenile in vitro embryo production outcomes in Merino ewe lambs. Karen Kind (Australia) 12.15 pm - 12.30 pmW126 - Field study: Plasma Anti Müllerian Hormone levels at OPU are predictive for antral follicle count in peri- and post-pubertal dairy heifers Erik Mullaart (The Netherlands) 12.30 pm - 12.45 pm W 127 - Influence of oxygen tension in the transcription pattern and cell differentiation of bovine embryos produced in vitro. Roberta Ferreira Leite (Brazil) 19 TUESDAY JUNE 28TH 11.00 am - 12.30 pmWorkshop: Spermatology AUDITORIUM PIERRE DE RONSARD Chairs: Xavier Druard (France) and Simon de Graaf (Australia) 11.00 am - 11.15 amW91 - Removal of sperm sialic acid increases polyspermic penetration and decreases cleavage and blastocyst rate in cattle Beatriz Fernandez-Fuertes (Ireland) 11.15 am - 11.30 amW92 - CatSper channels regulate bull sperm hyperactivation and rheotaxic response Gillian Johnson (Ireland) 11.30 am - 11.45 amW93 - Does the Presence of Bisected Spermatozoa and Their Debris Affect Fertility – AI Field Fertility Results for a New Commercial Scale Sperm Sexing Technology Marjorie Faust (USA) 11.45 am – 12.00 pmW94 - Purification of spermadhesin from ram seminal plasma Arlindo Moura (Brazil) 12.15 pm - 12.30 pmW95 - Receptor-mediated control of intracellular calcium stores in boar spermatozoa Dagmar Waberski (Germany) 11.00 am - 12.30 pmWorkshop: Camelids reproduction AUDITORIUM DESCARTES Chairs: Lulu Skidmore (United Arab Emirates) and Peter Nagy (United Arab Emirates) 11.00 am - 11.05 amW71 - Effect of stage of follicular development on embryo recovery rate and embryo quality in alpacas (Vicugna pacos) Wilfredo Huanca (Peru) 11.05 am - 11.10 amW710 - Artificial insemination of superovulated dromedary camels Samir ALBulushi (Australia) 11.10 am - 11.15 amW711 - Effect of seminal plasma added before or after freezing-thawing on alpaca semen cryopreservation Eduardo Aisen (Argentina) 11.15 am - 11.20 amW712 - Biochemical composition and protein profiles of seminal plasma and their correlation to post-thaw semen quality in Alpaca Nasrin Sultana Juyena (Bangladesh) 11.20 am - 11.25 amW72 - Resynchronization of the follicular wave in dromedary camels with unknown pregnancy status Bodhaganahalli Manjunatha (Sultanate of Oman) 11.25 am - 11.30 amW73 - The effects of protein supplement on in vitro maturation and embryonic development of dromedary (Camelus dromedarius) oocytes Amir Niasari-Naslaji (United Arab Emirates) 11.35 am - 11.40 amW75 - Comparing three extenders: Hashi, Green buffer and INRA 96, for short term preservation of dromedary camel semen Fahimehsadat Seyedasgari (Iran) 11.40 am - 11.45 amW76 - Effect of seminal plasma in the improving of reproductive performance in alpacas (Vicugna pacos) Wilfredo Huanca (Peru) 11.45 am - 11.50 amW77 - Variation of sperm characteristics among ejaculated semen fractions of dromedary camels (Camelus dromedarius) Meriem Fatnassi (Tunisia) 11.50 am - 11.55 amW78 - Effect of different concentrations of seminal plasma on sperm viability and acrosomal status in Llama Susan Giuliano (Argentina) 11.55 am - 12.00 pmW79 - The use of heterologous seminal plasma on artificial insemination of alpacas Walter Bravo (Peru) 20 TUESDAY JUNE 28TH ROOM DIANE DE POITIERS 11.00 am - 12.30 pmWorkshop: Reproductive pathologies Chairs: Francis Fieni (France) and Jean-François Bruyas (France) 11.00 am - 11.12 amW101 - Prevalence of subclinical endometritis at first service post-partum and its effect on the conception rate in dairy cows: preliminary results of a field study Osvaldo Bogado Pascottini (Belgium) 11.12 am - 11.24 amW102 - Potential use of immunohistochemistry as complementary tool in the diagnosis of subfertility in biopsies from Thoroughbred mares. Fidel Ovidio Castro (Chile) 11.24 am - 11.36 amW103 - Comparison of progesterone and inflammation parameters in subfertile young and old mares Elida Fumuso (Argentina) 11.36 am - 11.48 amW104 - Presence of bovine peripheral blood mononuclear cells amplified mRNA expression of pro-inflammatory genes in bovine endometrial epithelial cells cocultured with Trueperella pyogenes Mohammad Ibrahim (Germany) 11.48 am - 12.00 pmW105 - Canine brucellosis in foetuses and neonates from commercial breeding kennels. Tayse Souza (Brazil) 12.00 pm - 12.10 pmW106 - Impact of vaccination agains IBR, BVD and leptospirosis on reproductive rates of beef cows Isabela Avila (Brazil) 12.10 pm - 12.20 pmW107 - Study on the effect of chelated and non-chelated mineral supplementation in postpartum anoesturs graded murrah buffaloes Ram Chandra Reddy Komati Reddy (India) 12.20 pm - 12.30 pmW108 - Placental responses to water deprivation in pregnant ewes Sezen Ocak (Turkey) 11.00 am - 12.30 pmWorkshop: Wild animal reproduction ROOM CATHERINE DE MEDICIS Chairs: Tamara Keeley (Australia) and Robert McCorkell (Canada) 11.00 am - 11.15 amSeasonality and Breeding Success of Captive and Wild Tasmanian Devils (Sarcophilus harrisii) Tamara Keeley (Australia) 11.15 am - 11.30 amW81 - Assessment of reproductive status in great apes via different ultrasound approaches Barbara Drews (Germany) 11.30 am - 11.45 amW82 - Electrophilic aldehydes increase free radical production and modify proteins in stallion spermatozoa Sally Hall (Australia) 11.45 am - 12.00 pmW83 - Surface complexity and porosity of the zona pellucida of Wood Bison embryos and oocytes Taryn Roberts (Canada) 12.00 pm - 12.30 pm Questions 21 ... REPRODUCTION BIOTECHNOLOGIES EasyKit TM READY-TO-USE FLOW CYTOMETRY ASSAYS Simplify your life • Ease of use • Time-saving • Repeatable results • Safe handling EasyCyte TM SEMEN FERTILITY ANALYSIS Flow cytometer • Semen physiological parameters analysis • Made easy by IMV • Unique ready-to-use kits and software • Scientific training and follow-up www.imv-technologies.com TUESDAY JUNE 28TH 11.00 am - 12.30 pmWorkshop: Endocrine perturbators ROOM COURTELINE Chairs: Pascal Vaudin (France) and Nicole Hagen (France) 11.00 am - 11.15 amW111 - Gilts from male biased litters show greater ovulation than gilts from female biased litters in response to PG600. Cameron Ralph (Australia) 11.15 am - 11.30 amW112 - Effects of acylated ghrelin on GnRH-induced preovulatory gonadotropin surge in dairy heifers Georgios S Amiridis (Greece) 11.30 am - 11.45 amW113 - Protective role of vitamin E on arsenic induced toxicity in estes, serum biochemical constituents and lipid peroxidation of Teddy goat bucks Muhammad Zubair (Pakistan) 11.45 am - 12.00 pmW114 - Development of an integrated physiological model to predict human fetal exposure to endocrine disruptors, applied to Bisphenol A Nicole Picard-Hagen (France) 12.00 pm - 12.15 pmW115 - Reproductive effects of gestational exposure to diesel exhaust in a rabbit model Pascale Chavatte-Palmer (France) 12.45 pm - 1.30 pmIMV workshop: Semen analysis: a new perspective to improve fertility ROOM DIANE DE POITIERS 12.30 pm - 1.30 pm Lunch on the exhibition area 1.30 pm - 4.00 pmSymposium: Reproductive parameters of high yielding dairy cattle AUDITORIUM FRANCOIS Ier Chair: Roberto Sartori (Brazil) mbryo development in dairy cattle • E Patrick Lonergan (Ireland) Mechanisms underlying reduced fertility in anovular dairy cows • José Santos (USA) Pivotal periods for pregnancy loss during the first trimester of gestation in • lactating dairy cows Milo Wiltbank (USA) Effects of insulin resistance later in lactation on fertility of dairy cows • Pietro Baruselli (Brazil) S51 - Size of the conceptus in lactating Holstein dairy cows and nulliparous • heifers from d 33 to 45 of pregnancy is not associated with circulating glucose, insulin, IGF1, or progesterone concentrations Matthew Lucy (USA) 1.30 pm - 4.00 pmSymposium: Reproductive management in beef cattle production systems AUDITORIUM PIERRE DE RONSARD Chair: Michael Diskin (Ireland) • F actors affecting puberty in replacement beef heifers George Perry (USA) Endocrinology and the physiology of the post-partum beef cows • Michael Diskin (Ireland) 23 TUESDAY JUNE 28TH • C ontrol breeding technologies to increase use of AI Gabriel Bo (Canada) Reproductive management in beef cattle production systems • Jacob Thundathil (Canada) S102 - Relationships between productivity, calf mortality and reproductive • performance in French beef cows Bénédicte Grimard (France) 1.30 pm - 4.00 pmSymposium: Neuroendocrine control of reproductive function AUDITORIUM DESCARTES Chair: Anne Duittoz (France) • A dult Neurogenesis and physiological regulations in Mammals Martine Migaud (France) Seasonal breeding in mammals: from basic science to applications and back • Hugues Dardente (France) Transcriptome analyses identified five transcription factors differentially • expressed in the hypothalamus of post versus pre-pubertal Brahman heifers Marina Fortes (Australia) Prenatal programming of neuroendocrine functions • Niel Evans (UK) S81 - Hypothalamic dopamine modulation and salsolinol-induced prolactin • secretion in goats Tsutomu Hashizume (Japan) 1.30 pm - 4.00 pmSymposium: Placental function ROOM DIANE DE POITIERS Chair: Anne Tarrade (France) 1.30 pm - 2.05 pm Placentation in mammals: definitive placenta, yolk sac and paraplacenta Anthony Carter (Denmark) 2.05 pm - 2.40 pm Animal models for utero-placental imaging Olivier Morel (France) 2.40 pm - 3.15 pm Maternal environment and placental vascularization in small ruminants Larry Reynolds (USA) 3.15 pm - 3.50 pm Bovine placenta in vivo and in vitro Christiane Pfarrer (Germany) 3.50 pm - 4.00 pm S62 - The Transcriptome of the Endometrium and the Placenta of Holstein Cows is affected by Day of Gestation but not Lactation Stephen Moore (USA) 24 TUESDAY JUNE 28TH 1.30 pm - 4.00 pmWorkshop COST SALAAM: Recent developments in gene editing, phenotyping, and biobanking of large biomedical models ROOM CATHERINE DE MEDICIS 1.30 pm - 1.50 pmCOST Action BM1308 “Sharing Advances on Large Animal Models – SALAAM” – Progress and Perspectives Eckhard Wolf (Germany) 1.50 pm - 2.15 pmEfficient Gene Editing in Livestock Species Heiner Niemann (Germany) 2.15 pm - 2.40 pm Pig Models of Rare Monogenic Diseases Hiroshi Nagashima (Japan) 2.40 pm - 3.05 pm Cloned Dog Models in Biomedical Research Byeong Chun Lee (South Korea) 3.05 pm - 3.30 pm Effects of Maternal Obesity on Embryo and Fetal Development: the Choice of an Animal Model Pascale Chavatte Palmer (France) 3.30 pm - 3.45 pm Assessment of Glucose Homeostasis in Large Animal Models Pauline Peugnet (France) 3.45 pm - 4.00 pmThe Munich MIDY Pig Biobank Simone Renner (Germany) 4.00 pm - 4.30 pm Coffee break on the exhibition area 4.30 - 5.30 pmStudents Competition: Charles Thibault AUDITORIUM FRANCOIS Ier President: Philippe Chemineau (France) Jury: Patrick Lonergan (Ireland), Peter J Hansen (USA), Simon De Graaf (Australia), Ann Van Soom (Belgium) 4.30 pm - 4.42 pmPW1520 - Effects of feeding algae rich in DHA omega-3 fatty acid (FA) on reproductive performance, interferon-stimulated gene expression and milk FA composition in Holstein cows Leticia Sinedino (USA) 4.42 pm - 4.54 pm PW430 - HCG in early pregnancy increases estrogen and pregnancy rate for sows in summer. Jemma Seyfang (Australia) 4.54 pm - 5.06 pmW64 - Paternal effect on the miRNA content of bovine blastocysts Rolando Pasquariello (Italy) 5.06 pm - 5.18 pmPW323 - Generation and characterization of horse iPSCs using a lentiviral vector for their application in reproductive biotechnologies Lucia Moro (Argentina) 5.18 pm - 5.30 pmPW511 - Searching through the transcriptome of in vivo bovine oocytes led to the identification of 12 genes associated with high fertility Vittoria Bocchi (Italy) 5.30 pm - 7.00 pm Poster sessions on the exhibition area 25 WEDNESDAY JUNE 29TH 8.30 am - 10.30 amPlenary: Somatic environment and oocyte differentiation AUDITORIUM FRANCOIS Ier Chair: Svetlana Uzbekova (France) riving folliculogenesis by the oocyte-somatic cell dialogue: lessons from genetic • D models Danielle Monniaux (France) Somatic environment and germinal differentiation in antral follicle: the effect of • FSH withdrawal and basal LH on oocyte competence acquisition in cattle Marc-André Sirard (Canada) Bidirectional communication between cumulus cells and the oocyte: old hands • and new players? Jeremy Thompson (Australia) 10.30 am - 11.00 am Coffee break on the exhibition area 11.00 am - 12.30 pmWorkshop: Estrus cycle control and insemination AUDITORIUM FRANCOIS Ier Chairs: Gabriel Bo (Canada), Marcos Colazo (Australia), and Reuben Mapletoft (Canada) 11.00 am - 11.12 amW151 - Effects of estrous expression, body condition, and lameness on ovulation times and temperature of Holstein dairy cows Tracy Anne Burnett (Canada) 11.12 am - 11.24 amW152 - Association between proestrus length, preovulatory follicular diameter, estrus behavior and pregnancy rate in progesterone-estradiol’based treatment J-Synch for FTAI in Bos taurus beef heifers Richard Núñez Olivera (Uruguay) 11.24 am - 11.36 amW153 - Relationship between ear canal temperature oestrus onset and ovulation in beef heifers Federico Randi (Ireland) 11.36 am - 11.48 amW154 - Relationships among interferon-stimulated gene expression, endometrial thickness, and ovarian structures as potential predictors of non-pregnancy in dairy cows on day 21 after AI Milo C. Wiltbank (USA) 11.48 am - 12.00 pmW155 - Monitoring ventral tail-surface temperature by wearable wireless sensor predicts ovulation in cattle Koji Yoshioka (Japan) 12.00 pm - 12.30 pm Discussion 11.00 am - 12.30 pmWorkshop: Ultrasonography and other imaging methods AUDITORIUM PIERRE DE RONSARD Chairs: Eve Mourier (France), Christophe Richard (France) and Peter Bols (Belgium) 11.00 am - 11.15 am W181 - The Pulse Doppler ultrasound of the intra-testicular artery in stallions is a good indicator of sperm production Cristina Ortega-Ferrusola (Spain) 11.15 am - 11.30 am W182 - Comparison of Purebred and Crossbred embryos through time lapse Alline Reis (France) 11.30 am - 11.45 amW183 - Using ultrasonographic evaluation of endometrial thickness to predict nonpregnant dairy cows at day 21 after AI Gulnaz Yilmazbas-Mecitoglu (Turkey) 26 WEDNESDAY JUNE 29TH 11.45 am - 12.00 pmW184 - Preliminary morphometric study on fetal eye in Standarbred mares in late gestation Aliai Lanci (Italy) 12.00 pm - 12.15 pm W1828 - Probing for answers in Weddell seals: Ultrasonography reveals a pinniped that may not have an embryonic diapause Michelle Shero (USA) 11.00 am - 12.30 pmWorkshop: Embryo implantation AUDITORIUM DESCARTES Chairs: Olivier Sandra (France) and Niamh Forde (UK) 11.00 am - 11.15 amW131 - Gene expression in porcine preimplantation embryos during the onset of conceptus elongation Stefan Bauersachs (Switzerland) 11.15 am - 11.30 amW132 - Uterine epithelial cell changes during pregnancy in the domestic cat (Felis catus) and the Fat tailed dunnart (Marsupialia: Sminthopsis crassicaudata) Jessica Dudley (Australia) 11.30 am - 11.45 amW133 - Expression of amino acid transporters in equine endometrium and conceptus membranes during early pregnancy Charlotte Gibson (The Netherlands) 11.45 am - 12.00 pmW134 - Large-scale analysis of protein expression changes evoked by miR-26a and miR-125b in luminal epithelium of pregnant porcine uterus Monika M. Kaczmarek (Poland) 12.00 pm - 12.15 pmW135 - Contrasted maternal metabolism affects FOXL2 gene expression in dairy cattle Audrey Lesage-Padilla (France) 12.15 pm - 12.30 pmW136 - Influence of preovulatory estradiol on conceptus survival and uterine glucose transporter expression. Emmalee Northrop (USA) 11.00 am - 12.30 pmWorkshop: Embryo metabolism ROOM DIANE DE POITIERS Chairs: Jeremy Thompson (Australia) and Christine Wrenzycki (Germany) 11.00 am - 11.15 am W141 - Dietary rumen-protected omega-3 fatty acids promote elongation of preimplantation embryos in heifers Katrin Giller (Switzerland) 11.15 am - 11.30 am W142 - Regulation of PARylation mediated autophagy via mammalian target of rapamycin complex 1 (mTORC1) signaling during porcine blastocyst formation Hoon Taek Lee (South Korea) 11.30 am - 11.45 am W143 - Developmental kinetics alters the transcription pattern of stress-response related genes in in vitro produced bovine embryos. Camila Lima (Brazil) 11.45 am - 12.00 pm W144 - Predicting Cattle Embryo Quality Using Label Free-Diagnostics of Metabolism Mel Sutton-McDowall (Australia) 12.00 pm - 12.15 pm W145 - Leptin and insulin-like growth factor-1 concentrations are correlated in the uterine luminal fluid of superovulated dairy cows Miguel Velazquez (United Kingdom) 27 WEDNESDAY JUNE 29TH 11.00 am - 12.30 pmWorkshop: Evolution of omic tools and integration of omic data ROOM CATHERINE DE MEDICIS Chairs: Stefan Bauersachs (Switzerland) and Claudia Klein (Canada) W171 - Proteomic profiling of bovine cumulus cells after in vivo and in vitro maturation reveals alterations in numerous biological pathways Jasmin Walter (Switzerland) W172 - A quantitative proteomic comparison of epididymal and ejaculated ram spermatozoa Taylor Pini (Australia) W173 - Novel prostaglandin regulating mechanisms revealed by proteomic analysis of early equine pregnancy Aleona Swegen (Australia) 11.00 am - 12.30 pmWorkshop: Strategies for identification and conservation of genetic diversity ROOM COURTELINE Chairs: Thierry Joly (France) and Lucie Gavin-Plagne (France / The Netherlands) 11.00 am - 11.15 amW1601 - Reproductive parameters associated with genetic improvement are influenced by breed and selection intensity in Spanish horse breeds Sebastián Demyda Peyrás (Argentina) 11.15 am - 11.30 amW1602 - Development of a New Synthetic Prolific Dam Line (ANAROM) via ART in Turkey Ebru Emsen (Turkey) 11.30 am - 11.45 amW1603 - Females from transfer of Aubrac biopsied sexing in vivo embryos preserve the dairy genetic type Giselle Gamarra (France) 11.45 am - 12.00 pmW1604 - Population genetic structure and genetic diversity of Camelus Bactrianus and Camelus Dromedarius in Iran Nemat Hedayat Evrigh (Iran) 12.00 pm - 12.15 pmW1605 - Fertility Associated Metabolites in Bull Seminal Plasma and Blood Serum: 1H Nuclear Magnetic Resonance study Ajeet Kumar (India) 12.45 pm - 1.30 pmIMV workshop: Boar semen: innovative and safe production process ROOM CATHERINE DE MEDICIS 12.30 pm - 1.30 pm Lunch on the exhibition area 1.30 pm - 4.00 pmSymposium: Early maternal - embryo communication AUDITORIUM FRANCOIS Ier Chairs: Pilar Coy and Sebastián Cánovas (Spain) • C ross-talk during the periconception period Alireza Fazeli (UK) • Maternal-embryo interaction in the bovine oviduct: evidence from in vivo and in vitro studies Dimitrios Rizos (Spain) The role of relaxin in mare reproductive physiology: A comparative review with • other species Claudia Klein (USA) 28 ... REPRODUCTION BIOTECHNOLOGIES IVOS II THE STATE-OF-THE-ART IN SEMEN ANALYSIS Integrated system for both dose production and quality control evaluation. • Standardization • Objective and reliable measurement • Accuracy • Repeatability • Traceability Several options are available to allow for the use of fluorescence probes, create sub-populations of sperm, or view sperm track kinematics. PRE-CALIBRATED COUNTING CHAMBERS Disposable Leja counting chambers offer you the most reliable, quick, and accurate solution! • Specially designed for semen analysis • Tested not spermotoxic • Time-saving • Highest precision, repeatability and reliability • Accurate and constant chamber depth (20 micron) • Easy-to-use • Available with 4 or 8 chambers www.imv-technologies.com • T he functional role of insulin in fertility and embryonic development what can we learn from the bovine model? Denise Laskowski (Sweden) • S121 - Three-dimensional bovine oviduct cell cultures promote sperm activation and monospermic in vitro fertilization Heiko Henning (The Netherland) S122 - Estimation of HCO3- within the oviduct and uterus of pigs by in vivo • recoding of CO2 and pH. A preliminar study. Octavio López Albors (Spain) 1.30 pm - 4.00 pmSymposium: Genomics of the reproductive function AUDITORIUM PIERRE DE RONSARD Chair: John Williams (Australia) 1.30 pm - 2.10 pm Major Genes Influencing ovulation rate in Sheep as a Source of Basic Knowledge of Ovarian Function Stéphane Fabre (France) 2.10 pm - 2.50 pm Integrative approaches to enhance understanding and predicting complex fertility traits Stefan Bauersachs (Switzerland) 2.50 pm - 3.30 pm Mapping deleterious variants in dairy cattle Paolo Ajmone-Marsan (Italy) 3.30 pm - 3.40 pm S77 - Characterization of the exonic regions of the AMH gene in Nelore cattle Lindsay Unno Gimenes (Brazil) 3.40 pm - 3.50 pm PS212 - Genotyping and cryopreservation of in vitro produced porcine embryos Ayuko Uchikura (Japan) 3.50 pm - 4.00 pm S76 - Seeking Selection Signatures for Silent Estrus Behavior is Imperative to Exploit Livestock Capabilities Maryam Javed (Pakistan) 1.30 pm - 4.00 pmSymposium: Ovarian cortex and follicles culture AUDITORIUM DESCARTES Chair: Ricardo Figueiredo (Brazil) • Angiogenesis and its control in the bovine ovary Katie Woad (UK) In vitro manipulation of equine preantral follicles • Eduardo Gastal (USA) • Primate Follicular Development and Oocyte Maturation in 3-dimensional Culture Mary Zelinski (USA) Engineering the in the in vitro follicle environment • Lisa Green (USA) 30 Y Journal Publication New insights into the evolution of external genitals Sex Dev 9(1) 1–68 (2015) 9 | 1 | 15 online print e-ISSN 1661–5433 ISSN 1661–5425 ISBN 978–3–318–03022–8 Evolution of External Genital Development Editors M.B. Renfree, Melbourne, Vic. M. Schmid, Würzburg www.karger.com/sxd Evolution of External Genital Development Editors Marilyn B. Renfree Michael Schmid S. Karger Medical and Scientific Publishers Basel . Freiburg . Paris . London . New York . Chennai . New Delhi . Bangkok . Beijing . Shanghai . Tokyo . Kuala Lumpur . Singapore . Sydney Evolution of External Genital Development Editors:Renfree,M.B.(Melbourne,Vic.); Schmid, M. (Würzburg) 68p.,27fig.,20incolor,2tab.,2015 CHF29.00/EUR27.00/USD34.00(softcover) CHF35.00/EUR32.00/USD41.00(online) Online version for institutional purchase Pricessubjecttochange,VATnotincluded EURpriceforeurozonecountries,USDpricefor USAandLatinAmericaonly ISBN978–3–318–03022–8(softcover) e-ISBN978–3–318–03023–5 Special Topic Issue Sexual Development Vol. 9, No. 1, 2015 Included in subscription Listedinbibliographicservices,including Journal Citation Reports, PubMed/MEDLINE, Biological Abstracts, Embase Providing new insights into the developmental mechanisms involved in the evolution of external genitals, the articles in this special issue provide a comparative analysis across terrestrial vertebrates. The evolutionary transition from external to internal fertilization in vertebrates was facilitated by the emergence of novel organs, the external genitals. Reptiles as well as birds exhibit remarkable phenotypic diversity, ranging from the paired hemipenises of snakes and lizards, to the elaborate corkscrew penises of waterfowl, and to the complete absence of an intromittent penis in most birds. This special topic issue presents new studies on the external genital development in birds, lizards, snakes, alligators, and turtles. The articles discuss new insights into the evolutionary developmental biology (‘evo-devo’) of external genitals and provide explanations for the evolution of human congenital malformations, such as hypospadias. Offering novel perspectives on the evolution of reproductive organs, Evolution of External Genital Development will be of special interest to developmental and reproductive biologists as well as comparative and evolutionary morphologists. Contents Preface: Renfree, M.B.; Schmid, M. •DevelopmentofHemipenesintheBallPython Snake Python regius: Leal, F.; Cohn, M.J. •DevelopmentoftheCloaca,Hemipenes,and HemiclitoresintheGreenAnole,Anolis carolinensis: Gredler, M.L.; Sanger, T.J.; Cohn, M.J. •PhallusDevelopmentintheTurtleTrachemys scripta: Larkins, C.E.; Cohn, M.J. •DevelopmentofAvianExternalGenitalia: InterspecificDifferencesandSexualDifferentiation of the Male and Female Phallus: Herrera, A.M.; Brennan, P.L.R.; Cohn, M.J. •MorphogenesisandPatterningofthePhallusand CloacaintheAmericanAlligator,Alligator mississippiensis: Gredler, M.L.; Seifert, A.W.; Cohn, M.J. AuthorIndex For more special topic issues, please visit www.karger.com/sxd Karger – Medical and Scientific Publishers CH–4009Basel,Switzerland [email protected],f:+41613061234 www.karger.com KI15279 The easiest way to order: w w w.karger.com/sxd 1.30 pm - 4.00 pmSymposium: Biomedical applications of transgenesis ROOM DIANE DE POITIERS Chair: Eckhard WOLF omparative aspects of rodent and non-rodent animal models for mechanistic • C and translational diabetes research Simone Renner (Germany) Growing human organs in pigs – a dream or reality? • Hiroshi Nagashima (Japan) • Lessons learned from the cystic fibrosis pig David Meyerholz (USA) • Pigs as models of human cancers Angelika Schnieke (Germany) 4.00 pm - 4.30 pm Coffee break on the exhibition area 4.30 pm - 5.30 pm Poster sessions on the exhibition area 8.00 pm - 00.00 am Gala dinner (La Grange de Meslay) 33 The sPEcialists offering The compleTe producT range for artificial insEMination and EMbryo transfEr. SIMMET P R I Z E FOR ASSISTED REPRODUCTION www.minitube.com We proudly congratulate Professor Katrin HinricHs on receiving the siMMEt PriZE for outstanding achievements as a diligent scientist in basic and applied research in the field of Assisted Animal Reproduction. THURSDAY JUNE 30TH 8.30 am - 10.30 amPlenary: Epigenetic control in gametes and embryos Chair: Ann Van Soom (Belgium) AUDITORIUM FRANCOIS Ier pigenetic remodeling during preimplantation mammalian development • E Pablo Ross (USA) Epigenetic reprogramming in mammalian species after somatic cloning • Heiner Niemann (Germany) Comparative aspects of epigenetic reprogramming in the early embryo model and • agricultural species Nathalie Beaujean (France) P41 - Axin stabilization impairs zygotic genome activation and histone acetylation • in the mouse Andrès Gambini (USA) P42 - Analysis of paternally derived epigenetic alterations in bovine early • embryonic development after in vitro fertilization Sarah Wyck (Switzerland) 11.00 am - 1.00 pmPlenary: Developmental origin of adult animal health and animal production AUDITORIUM FRANCOIS Ier Chair: Pascale Chavatte-Palmer (France) 11.00 am - 11.35 amManagement of the pregnant mare and long term consequences on the offspring Pauline Peugnet (France) 11.35 am - 12.10 pm Developmental Origins of Health and Disease in swine: implications for animal production and biomedical research Antonio Gonzalez-Bulnes (Spain) 12.10 pm - 12.40 pmDevelopmental programming, adiposity and reproduction in ruminants Michael Symonds (UK) 12.40 pm - 12.50 pm P51 - Nicotinamide mononucleotide (NMN) can partly rescue maternal diet-induced altered gene expression in offspring ovaries Michael J. Bertoldo (Australia) 12.50 pm - 1.00 pm P52 - Maternal age but not parity affected daughter’s fertility during first lactation. Irene Lopez-Helguera (Spain) CLOSING CEREMONY AUDITORIUM FRANCOIS Ier 35 PLATINUM SPONSOR BRONZE SPONSOR 36 EXHIBITORS AND SPONSORS 37 COFFEE BREAKS & LUNCH BOXS DISTRIBUTION 38 POSTER AREA COFFEE BREAKS & LUNCH BOXS DISTRIBUTION EXHIBITOR FLOOR PLAN BCF TECHNOLOGY BIOSCIENTIFICA IVF BIOSCIENCE RESEARCH INSTRUMENTS VETOQUINOL IMV MAI ANIMAL HEALTH DRAMINSKI POSTER AREA ECM LA BALADE GOURMANDE COFFEE BREAKS & LUNCH BOXS DISTRIBUTION COFFEE BREAKS & LUNCH BOXS DISTRIBUTION MINITUBE NIKON BIOMERIEUX 39 ADMINISTRATIVE OFFICE www.icar2016.org