GENETIKA 2015 CONGRESS PROGRAMME

GENETIKA 2015
20-23 September 2015
Rogaška Sla�na
Slovenia
7th CONGRESS OF THE SLOVENIAN GENETIC SOCIETY
and
th
7 MEETING OF THE SLOVENIAN SOCIETY OF HUMAN GENETICS
CONGRESS PROGRAMME
PROGRAMME - GENETIKA 2015
September 20th, 2015
Sunday
10:00 - 14:00
BioBash WorkShop organized by Genialis
Registration
13:00 - 15:00
15:00 - 15:20
15:20 - 16:00
15:20 - 16:00
Opening ceremony
Opening lecture
Branka Javornik
Michael J. Havey*
CUCUMBER AS A MODEL PLANT TO STUDY MITOCHONDRIAL-NUCLEAR
INTERACTIONS
Break
16:00 - 16:30
Section 1
16:30 - 18:30
16:30 - 16:55
Genetic diseases I
Nadja Kokalj-Vokač, Damjan Glavač
Paolo Gasparini*
GENETICS OF TASTE AND FOOD PREFERENCES: IMPACT ON HEALTH
STATUS
16:55 - 17:20
Metka Ravnik-Glavač*
17:20 - 17:45
Andre Franke*
17:45 - 18:00
18:00 - 18:15
Peter Dovč
Emanuela Boštjančič
18:15 - 18:30
Giorgia Girotto
SLOVENIAN AMYOTROPHIC LATERAL SCLEROSIS: MUTATIONS AND
MIRNA EXPRESSION
INFLAMMATORY BOWEL DISEASES - FROM GWAS TO SYSTEMATIC
HOST-MICROBIOME INTERACTION STUDIES
PROBLEMS WITH SMALL POPULATIONS: EXAMPLE OF DOG BREEDS
MICRORNA SIGNATURES IN OPERABLE RECURRENT GLIOBLASTOMA
BEFORE AND AFTER TREATMENT
WHOLE EXOME SEQUENCING FOR THE STUDY OF HEREDITARY
HEARING LOSS: PSIP1/LEDGF AS A NEW GENE CAUSING
SENSORINEURAL PROGRESSIVE HEARING LOSS AND VARIABLE EYE
PHENOTYPES
Welcome reception
19:30
September 21th, 2015
Monday
Section 2:
9:00 - 10:35
9:00 - 9:25
Genome Analysis I
Branka Javornik, Roberto Bacilieri
Roberto Bacilieri*
CONTRIBUTION OF GENETICS AND GENOMICS TO DECRYPT
DOMESTICATION IN GRAPE
9:25 - 9:50
Nataša Štajner*
9:50 - 10:05
10:05 - 10:20
Andreja Čerenak
Aida Dervishi
10:20 - 10:35
Break
10:35 - 11:00
Section 3:
11:00 - 12:35
11:00 - 11:25
11:25 - 11:50
Jernej Jakše
GENETIC ANALYSIS OF WESTERN BALKAN GRAPEVINES (VITIS VINIFERA
L.)
SUPPORT OF MOLECULAR APPROACHES IN CLASSICAL HOP BREEDING
THE SSR BASED GENETIC STRUCTURE OF ALBANIAN OLIVES (OLEA
EUROPAEA L.)
HOP PLANT RESPONSE AFTER VIROID INFECTION
Gene Therapy
Maja Čemažar, Gaëlle Vandermeulen
Gaëlle Vandermeulen* LOCAL DELIVERY OF DNA VACCINES BY ELECTROTRANSFER
Gregor Serša*
ELECTROCHEMOTHERAPY BOOSTED WITH IMMUNOGENE
ELECTROTRANSFER CAN BE USED AS IN SITU VACCINATION FOR
SUCCESFUL TUMOR TREATMENT
11:50 - 12:05
Vesna Tlaker Žunter
12:05 - 12:20
Veronika Stoka
12:20 - 12:35
Urška Kamenšek
NEW THERAPEUTIC OPTIONS FOR NEVOID BASAL CELL CARCINOMA
(GORLIN) SYNDROME
STRUCTURAL AND FUNCTIONAL ANALYSIS OF HUMAN CATHEPSIN F
PATHOGENIC MUTATIONS, AN ENZYME INVOLVED IN KUFS DISEASE TYPE B
CONSTRUCTING CLINICALLY APPLICABLE ANTIBIOTIC-FREE PLASMIDS
FOR GENE ELECTROTRANSFER MEDIATED IMMUNO AND
ANTIANGIOGENIC THERAPY OF CANCER
Lunch
12:35 - 13:50
Guided tour in Rogaška Slatina
13:50 - 16:00
Section 4:
16:00 - 18:00
16:00 - 16:25
16:25 - 16:50
16:50 - 17:15
Pharmacogenomics
Vita Dolžan, Uroš Potočnik
Henk-Jan Guchelaar*
CLINICAL PHARMACOGENOMICS AND PERSONALIZED MEDICINE:
WHERE ARE WE?
Vita Dolžan*
PHARMACOGENETICS OF TYPE 2 DIABETES TREATMENT
Uroš Potočnik*
GENOME WIDE ASSOCIATION AND EXPRESSION STUDIES OF ANTI-TNF
THERAPY IN CHRONIC IMMUNE DISEASES AND PHARMACOGENOMICS
OF CROHN´S DISEASE
17:15 - 17:30
Damjan Glavač
THE PREDICTIVE VALUE OF MGMT PROMOTOR METHYLATION IN
GLIOBLASTOMA PATIENTS
17:30 - 17:45
Katja Repnik
17:45 - 18:00
Saba Battelino
PHARMACOGENOMIC GENOME WIDE ASSOCIATION STUDIES IN
CHILDHOOD ASTHMA
Break
18:00 - 18:30
Poster Session I
18:30 - 20:00
GENETIC BACKGROUND OF AUTOSOMAL RECESSIVE NONSYNDROMIC
HEARING LOSS IN SLOVENIAN POPULATION
September 22nd, 2015
Tuesday
Section 5
8:30 - 10:15
8:30 - 8:45
8:45 - 9:00
Golden Chromosome I
Branka Javornik, Damjan Glavač
Kristina Marton
IN SILICO SECRETOME AND EFFECTOR CANDIDATES OF THE
PHYTOPATHOGENIC FUNGUS VERTICILLIUM ALBO-ATRUM
Vasja Progar
HOP RESPONSE TO VERTICILLIUM INFECTION INVESTIGATED BY RNASEQ
9:00 - 9:15
Tanja Guček
9:15 - 9:30
Zala Kolenc
DIAGNOSTIC METHODS FOR DETECTION OF VIROIDS FROM HOP
(HUMULUS LUPULUS L.)
HOP (HUMULUS LUPULUS L.) RESPONSE MECHANISMS UNDER
DROUGHT STRESS
9:30 - 9:45
Mateja Zupin
9:45 - 10:00
Špela Kos
10:00 - 10:15
Urška Lampreht
IDENTIFICATION OF QUANTITATIVE TRAIT LOCI FOR DROUGHT
TOLERANCE IN COMMON BEAN (PHASEOLUS VULGARIS L.)
TARGETING THE SKIN CELLS BY THE DELIVERY OF PLASMID DNA UNDER
THE CONTROL OF TISSUE-SPECIFIC PROMOTER
EVALUATION OF PLASMID ENCODING CANINE IL-12 IN IN VIVO AND IN
VITRO EXPERIMENTS ON CANINE MALIGNANT MELANOMA CELLS
Break
10:15 - 10:45
Section 6
Golden Chromosome II
10:45 - 12:45
Uroš Potočnik, Damjan Glavač
10:45 - 11:00
Ajda Prevc
ANTITUMOR AND VASCULAR TARGETED EFFECTS OF ANTI-ENDOGLIN
GENE THERAPY IN VIVO
11:00 - 11:15
Gašper Klančar
NEXT GENERATION SEQUENCING AND NATIONAL UNIVERSAL
HYPERCHOLESTEROLEMIA SCREENING FOR CHILDREN
11:15 - 11:30
Alenka Matjašič
11:30 - 11:45
Ida Djurdjevič
LONG NON-CODING RNAS, IMPORTANT IN BRAIN DEVELOPMENT, ARE
ABERRANTLY EXPRESSED IN GLIOMA
NEW INSIGHTS INTO CELLULAR AND MOLECULAR MECHANISMS
CONTRIBUTING TO THE LABYRINTHINE PIGMENT PATTERN OF MARBLE
TROUT SKIN
11:45 - 12:00
Marko Flajšman
IDENTIFICATION OF VIRULENCE FACTORS OF THE PHYTOPATHOGENIC
FUNGUS VERTICILLIUM ALBO-ATRUM BY FUNCTIONAL ANALYSIS OF
TWO CANDIDATE VIRULENCE GENES OBTAINED BY PROTEOMIC
ANALYSIS
12:00 - 12:15
Matjaž Deželak
12:15 - 12:30
Barbara Jenko
12:30 - 12:45
Carina E. P. Kozmus
THE CLINICAL OUTCOME OF TREATMENT WITH ANTI-TNF-Α DRUG
ADALIMUMAB IN CROHN'S DISEASE PATIENTS IS ASSOCIATED WITH
SINGLE-NUCLEOTIDE POLYMORPHISMS IN NFKB1, BUT NOT IN
NFKBIA
CAN WE PREDICT METHOTREXATE TREATMENT RESPONSE IN
RHEUMATOID ARTHRITIS?
CANNABINOID RECEPTOR 2 GENE POLYMORPHISMS ARE ASSOCIATED
WITH CHILDHOOD ASTHMA SEVERITY AND TREATMENT OUTCOME
Lunch
12:45 - 14:15
Poster Session II
14:15 - 15:45
Section 7:
15:45 - 17:15
15:45 - 16:10
Bioinformatics
Simon Horvat, Nicholas Morton
Nicholas Morton*
TST GENE: MULTI-TASKING IN THE MITOCHONDRIA TO MODULATE
METABOLIC DISEASES
16:10 - 16:35
16:35 - 17:00
Blaž Zupan*
Tanja Kunej*
17:00 - 17:15
Vid Jelen
DATA FUSION (OF EVERYTHING)
INTEGROMICS TIME; A WEB PLATFORM FOR INTEGRATION AND
PRIORITIZATION OF GENOMICS DATA: 2015 UPDATE
RECONSTRUCTING A MITOCHONDRIAL GENOME FROM NEXT
GENERATION SEQUENCING READS WITH BIOINFORMATIC PROCEDURES
Break
17:15 - 17:45
Section 8
17:45 - 19:05
17:45 - 18:10
18:10 - 18:35
Genome Analysis II
Borut Bohanec, Michael Havey
Nadja Kokalj-Vokač*
MOLECULAR KARYOTYPING IN PRENATAL DIAGNOSIS
Borut Bohanec*
GENETICALLY MODIFIED PLANTS: CAUSES OF PUBLIC FEAR AND
POSSIBLE OUTCOMES
18:35-18:50
Andrej Zupan
18:50-19:05
Jasna Paradiž
THE GENETIC STRUCTURE OF SLOVENIAN MTDNA GENE POOL AND ITS
RELATIONSHIP WITH OTHER POPULATIONS
PGD BIOASSAY OF DEVIATING GALANTHUS NIVALIS VARIANTS
APPLICABLE TO ENVIRONMENTAL ALTERATIONS
Congress dinner
20:00
September 23rd, 2015
Wednesday
Section 9
9:00 - 10:45
9:00 - 9:25
Genetic diseases II
Metka Ravnik-Glavač, David Križaj
David Križaj*
TRP CHANNELS REGULATE MECHANOSENSING, INTRACELLULAR
SIGNALING AND NEURODEGENERATION IN THE MAMMALIAN EYE
9:25 - 9:50
Maja Čemažar*
ANTI-ENDOGLIN CANCER GENE THERAPY: VASCULAR TARGETED AND
ANTITUMOR EFFECTIVENESS
9:50 - 10:15
10:15 - 10:30
Rok Keber*
Špela Stangler Herodež
THE ROLE OF REGNASE-1 IN ADAPTIVE IMMUNE SYSTEM
METHYLATION ANALYSIS OF TUMOR SUPPRESSOR GENES IN HEAD AND
NECK SQUAMOUS CELL CARCINOMA
10:30 - 10:45
Tinkara Šilc
FAMILIAL ERYTHROCYTOSIS: REVIEW OF ENSEMBL GENOMIC
DATABASES AND MUTATION ANALYSIS
Break
10:45 - 11:15
Section 10
11:15 - 12:55
11:15 - 11:40
Interaction Genome - Environment
Metka Filipič, Darja Žgur Bertok
Metka Filipič*
GENOTOXIC EFFECTS OF THE RESIDUES OF ANTICANCER DRUGS TO
AQUATIC ORGANISMS
11:40 - 12:05
Ines Mandič Mulec*
12:05 - 12:30
12:30 - 12:55
Frederic Taieb *
Jerica Sabotič *
KIN DISCRIMINATION BETWEEN SYMPATRIC BACILLUS SUBTILIS
ISOLATES
GENOTOXIC ESCHERICHIA COLI, NOT ALL THE SAME...
LECTINS AND PROTEASE INHIBITORS IN DEFENSE OF FUNGAL FRUITING
BODIES
Break
12:55 - 13:15
13:15 - 13:55
13:15 - 13:55
Closing lecture
Metka Filipič
Darja Žgur Bertok*
THE BACTERIAL DNA DAMAGE REPAIR SOS SYSTEM GOVERNS
BACTERIAL COMPETITION
Lunch
13:55 - 15:10
15:10 - 17:00
*-invited lecture
Concluding remarks
SGD Assembly
POSTERS- GENETIKA 2015
P01
Investigation of the brain region specific proteome profile
alterations in neonatal Alzheimer's mouse model
Baykal AT, Mazi AR, Arzuman AS
P02
Benzoic acid derivatives with improved antifungal activity: design,
synthesis, SAR and CYP53 docking studies
Berne S, Kovačič L, Sova M, Kraševec N,
Gobec S, Križaj I, Komel R
P03
Increased expression of DNA PRRs after gene electrotransfer of
blank plasmid
Bošnjak M, Žnidar K, Heller L, Čemažar
M
P04
Cryopreservation by encapsulation-dehydration may affect
morphology and genetic stability of endemic Hladnikia
pastinacifolia (Apiaceae).
Ciringer T, Šajna N, Ambrožič-Dolinšek J
P05
Plant genetic resources at the Biotechnical Faculty of the
University of Ljubljana
Čop J, Osterc G, Baričevič D, Rozman L,
Luthar Z
P06
X chromosome inactivation in girls with intellectual disabilities
Erjavec Škerget A, Jurkovič I, Stangler
Herodež Š, Zagradišnik B, Kokalj Vokač N
P07
Investigation of the brain extracellular matrix in the early stage of
the Alzheimer's mouse model by proteomics analysis
Gurel B, Sevinc C, Cansev M, Baykal AT
P08
Morphological characterization of seeds and aleurone layer of
various wheat species (Triticum spp.)
Hribar A, Brinovec M, Kastelec D, Luthar
Z
P09
Genetic analysis and floral morphology of some Epipactis taxa
from different geographic regions
Ivanuš A, Urbanek Krajnc A, Lipovšek M,
Šiško M, Bohanec B, Luthar Z
P10
Downregulation of the miR-200 family in inflammatory bowel
disease – hallmark of epithelial-mesenchymal transition
Jerala M, Boštjančič E, Glavač D, Zidar N
P11
Identification and differentiation of Verticillium species with PCR
markers and sequencing of ITS region
Jeseničnik T, Štajner N, Jakše J, Radišek
S, Javornik B
P12
Preliminary study of bacterial diversity in human dishwashers
Koren S, Kovač M, Toplak N
P13
The impact of next generation sequencing on genetic diagnostics
of orphan diseases: Examples from Slovenian pediatric population
Kovač J
P14
Fungal actinoporin-like proteins
Kraševec N, Belc S, Novak M, Sepčić K,
Maček P, Anderluh G
P15
Cytokine gene polymorphisms in Slovenian women with solitary
and multiple uterine leiomyomas
Krsteski J, Jurgec S, Potočnik U
P16
The development of a genetic method to diagnose Type I primary
hyperoxaluria in "Coton de Tulear" dog breed
Lipnik K, Berginc G, Deželak M, Potočnik
U
P17
Students’ attitude to genetically modified forest trees in forest
plantations in Slovenia
Luthar Z, Božič G, Brus R
P18
Students’ opinion on genetically modified organisms
Malačič N, Černič Istenič M, Luthar Z
P19
Somatic mutations of calreticulin in essential thrombocythemia
Mandelc Mazaj MJ, Pajič T, Sever M,
Černelč P
6
P20
Microsatellite analysis revealed extensive genetic diversity of
common bean from Balkan region
Maras M, Pipan B, Šuštar-Vozlič J, Meglič
V
P21
Computational prediction of miRNA genes in hop (Humulus
lupulus L.) genome
Mishra AK, Duraisamy GS, Matoušek J,
Javornik B, Jakše J
P22
Genotoxic potential of cisplatin, 5-FU, etoposide and imatinib
mesylate in human hepatoma HepG2 cells
Novak M, Žegura B, Baebler Š, Štern A,
Rotter A, Stare K, Filipič M
P23
Utilization of molecular methods for hop (Humulus lupulus L.)
genotype evaluation
Patzak J, Henychová A
P24
Metrological assessment of one qPCR platform and two digital
PCR platforms for quantification of human cytomegalovirus
Pavšič J, Žel J, Milavec M
P25
Prevalences of iron uptake system genes among Escherichia coli
isolated from skin and soft-tissue infections and feces of healthy
humans
Predojević L, Žgur-Bertok D, Starčič
Erjavec M
P26
Development of PCR markers associated with cytoplasmic male
sterility in white cabbage (Brassica oleracea var. capitata L.)
Rudolf Pilih K, Podržaj A, Bohanec B,
Murovec J
Effect of low storage temperature on gene expression of PVY NTN
P27
infected potato tubers
Sedlar A, Gerič Stare B, Mavrič Pleško I,
Maras M, Šuštar-Vozlič J, Dolničar P,
Meglič V
P28
The role of transcription factor HLWRKY1 in regulatory network of
lupulin biosynthesis
Siglová K, Kocábek T, Duraisamy GS,
Mishra AK, Tsushima T, Sano T,
Matoušek J
P29
Genetic risk prediction in Slovenian Crohn’s disease patients
Skok K, Zupančič K, Repnik K, Skok P,
Potočnik U
P30
Manipulation of ploidy in zucchini (Cucurbita pepo L.): production
of haploids and polyploids
Stajič E, Murovec J, Bohanec B
P31
Expec virulence associated genes and pathogenicity islands among
Starčič Erjavec M, Žgur-Bertok D
commensal Escherichia coli isolated from healthy humans
P32
Non-invasive prenatal testing for Down syndrome and other
chromosomal abnormalities: the clinical study
Strah D, Perin P, Bernik J
Database of microRNA genes regulated by DNA methylation in
P33 cancer: 2015 update, biomarker prioritization and identification of
novel miRNA-cancer associations
Strmšek Ž, Močnik Roner M, Zorc M,
Kunej T
P34
Expression and activity of the Escherichia coli genotoxin Usp
Šakanović A, Korošec M, Podlesek Z,
Žgur Bertok D
P35
Pilot sequencing of the hypomethylated fig (Ficus carica L.) gene
space
Škalič M, Štajner N, Nečimer N, Javornik
B, Jakše J
P36
Mutations in ACADM of the first two patients with MCAD
deficiency in Slovenia
Šmon A, Repič Lampret B, Grošelj U,
Žerjav Tanšek M, Battelino T
P37
Gene expression analysis of hop samples (Humulus lupulus L.)
infected with Verticillium albo-atrum
Švara A, Štajner N, Cregeen S, Jakše J,
Javornik B
P38
Telomere lengths as a perspective marker in juvenile patients with Tesovnik T, Kovač J, Hovnik T, Dovč K,
Battelino T, Trebušak Podkrajšek K
type 1 diabetes
7
P39
Is cyanobacterial neurotoxin β-N-methylamino-L-alanine
genotoxic?
Tomc J, Novak M, Filipič M, Žegura B
P40
In vitro germination of Corylus avellana pollen as a rapid,
inexpensive research and teaching method
Vižintin L
P41
In vitro rescue of genotypes of the European chestnut (Castanea
sativa Mill.) attacked with chestnut gall wasp (Dryocosmus
kuriphilus Yasumatsu)
Vollmeier R, Osterc G, Luthar Z
P42
Prenatal diagnosis and molecular cytogenetic characterization of
de novo partial 7p duplication in a fetus with trisomy X
Zagorac A, Blatnik A, Zagradišnik B,
Erjavec Škerget A, Stangler Herodež Š,
Mujezinović F, Kokalj Vokač N
Detection of copy number variations in head and neck cancers of
P43
oral cavity and oropharynx/hypopharynx
P44
Genotoxic effects of the cyanobacterial pentapeptide nodularin in
HepG2 cells
Zagradišnik B, Krgović D, Stangler
Herodež Š, Zagorac A, Erjavec Škerget A,
Lanišnik B, Ćižmarević B, Kokalj Vokač N
Žegura B, Štraser A, Rotter A, Novak M,
Filipič M
8
Dolinškova 8, 1000 Ljubljana
Tel. 01 4273213, 4283650, Fax 01 4273191
E-mail: [email protected]
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