C o n f e r e n C e B o o k l e t - Nanoscale

Transcription

B o o k l e t
C o n f e r e n c e
Trilateral Symposium
on NanoBio Integration
September 30 - October 3, 2010
Freie Universität Berlin
Participating Institutions
and Centers
MATERIALS RESEARCH SCIENCE &
ENGINEERING CENTER
Poly 4 Bio
Polmeric Materials for
Biomedical Application
About this Symposium
The Berlin-Brandenburg area has many excellent and interdisciplinary working research groups in the areas of biomaterial development, design of stimuli-responsive polymers, development of
nanoscale architectures for drug-delivery and regenerative therapies. Scientists from the Charité Universitätsmedizin Berlin, the
Freie Universität Berlin, the research institutions GKSS Center for
Biomaterial Development, and the Max-Planck Institute of Colloids and Interfaces are closely working together in joint projects.
Centers like the Berlin-Brandenburg Center for Regenerative
Therapies and focus areas like Nanoscale Functional Materials were
established between the partners.
International clusters of excellence in the field of biomaterial development, bio-nano integration, and regenerative therapies exist at
the Harvard University, The University of Tokyo and the Freie Universität Berlin with its partner institutions. Internationally visible
scientists are working in centers like the WYSS Institute in Harvard
and the Center for NanoBio Integration in Tokyo as well as in the
Center for Nanoscale Functional Materials in Berlin.
The scope of this Trilateral Symposium is to identify areas of common interests, where the expertise of the different partners are
complementary in that way, that complex research goals can be
accomplished in a transnational collaboration. Some ideas for joined projects are:
• Exchange of individual scientists funded by the respective
centers or national institutions (e.g., DFG, NSF, JSPS)
• International graduate schools to achieve a PhD education
with interdisciplinary backgrounds
• Joint Research Labs for long term exchange of scientists
and to a better visibility
• Establishment of Transnational Clusters of Excellence as a
long term goal
With this brainstorming ideas in mind I am looking forward to an
inspiring meeting and fruitful discussions.
I welcome you sincerely to the exciting city of Berlin and to the
Freie Universität Berlin.
Rainer Haag
Trilateral Symposium • Berlin, October 2010 |
3
Scientific Program
September 30, 2010 (Thurs.)
Arrival and check in at Seminaris CampusHotel
18.30 Welcome Dinner (Seminaris)
October 1, 2010 (Fri.)
8.30Registration
8.40
Welcome Address and Objectives of the Symposium
Rainer Haag (FU Berlin)
8.50
Address by the Director of the
Center for Cluster Development
Carsten Dreher (FU Berlin)
9.00
Session 1: Center Presentations
Chairperson: Rainer Haag (FU Berlin)
• Nanobio Integration for Medical Innovation:
Challenge to Smart Molecular Therapy
Kazunori Kataoka (CNBI, Univ. Tokyo)
• Wyss Institute for Biologically Inspired Engineering:
A New Paradigm for Technology Innovation
Don Ingber (WYSS, Harvard)
• Nanoscale Functional Materials
Stefanie Reich (Nanoscale, FU Berlin)
Q&A panel and discussion (15 min)
10.15 Coffee break
10.40 Session 2: Bioinspired Materials
Chairperson: Don Ingber (Harvard, WYSS)
• Adaptive Bioinspired Materials
Joanna Aizenberg (Harvard, WYSS)
• Unravelling the Materials Basis of Plant Actuation
Peter Fratzl (MPI KG)
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| Trilateral Symposium • Berlin, October 2010
Scientific Program
• Multivalent Interactions with new Dimensions
Rainer Haag (FU Berlin)
• Evaluation of Network Structure and Physical Properties
of Tetra-PEG Gel
Takamasa Sakai (Univ. Tokyo)
Q&A panel and discussion with focus on joint activities
and perspectives (30 min)
12.30 Lunch at Seminaris
14.00 Session 3: Biomaterials and new Formulations in
Biomedical Applications
Chairperson: Kazunori Kataoka (Univ. Tokyo)
• Formulation of New Soft Nanomaterials
David Weitz (Harvard)
• Designing (Multi)functional Polymer Networks
and Exploring their Application Potential for
Regenerative Therapies
Andreas Lendlein (GKSS)
• Nanostructured Phospholipid Polymer Brush as
Biointerfaces
Kazuhiko Ishihara (Univ. Tokyo)
• Regenerative Therapies for Muscoskeletal Diseases
Georg Duda (Charité)
15.50 Young Investigator Presentations (7 x 10 min,
incl. short Q&A)
17.00 Coffee break and FU Berlin lab visits (chemistry /
biochemistry / physics labs)
19:00 Dinner at Alter Krug
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Scientific Program
October 2, 2010 (Sat.)
8.40
Session 4: Nanomachines and Single Proteins
on Surfaces
Chairperson: Stefanie Reich (FU Berlin)
• Programmed Molecular Assembly for Tailored
Functional Materials
Takuzo Aida (Univ. Tokyo)
• Single Molecules in Nanostructures
Adam Cohen (Harvard)
• Effect of Membrane Potential on the Photo-Cycle of
Sensory Rhodopsin
Kenichi Ataka (FU Berlin)
• Single-Molecule Analyses of Functions and Interactions of
Biomolecules by Nano- and Microdevices
Takashi Funatsu (Univ. Tokyo)
10.30 Group Picture
10.40 Coffee break
11.00 Session 5: Nanobiomaterials for Delivery
Chairperson: Andreas Lendlein (GKSS Teltow / FU Berlin)
• Biocompatible Polyplex Nanomicelle for Safe and Effective
Gene Transfer
Keiji Itaka (Univ. Tokyo)
• Carrier-mediated metal-ion transport and bioavailability
Gerd Multhaup (FU Berlin)
• Engineering Vascular Networks
Eduardo A. Silva (Harvard)
12.30 Lunch at Seminaris
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Scientific Program
14.00 Young Investigator Presentations (12 x 10 min,
incl. short Q&A)
16.00 Coffee and Round Table Discussion (room 12.12)
Return to hotel
18.00 Pick up at hotel for sightseeing in the city of Berlin
20.00 Dinner at Historische Weinstube
October 3, 2010 (Sun.)
09.00 Brainstorming brunch (Seminaris)
11.00 Visit to Potsdam Palace and Sanssoucis
15.00 Opening of the POLYDAYS 2010 Symposium
(Henry Ford Building, Gary Str. 35, 14195 Berlin,
FU Campus)
Location
The Trilateral Symposium will be held at the Institut für Chemie
und Biochemie, FU Berlin, Takustr. 3, 14195 Berlin, in the main
lecture hall and the seminar room 12.12. The Brainstorming
Brunch on Sun. Oct. 3, 2010 will be at Seminaris, Takustr. 39, 14195
Berlin. For a map see back cover.
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Young Investigator
Scientific Program
Presentations
October 1, 2010 (Fri.), 15.50 - 17.00
• The Relationship Between Network Structure and
Mechnical Properties in Stiff Biopolymer Networks
Louise Jawerth (Harvard / Weitz Group)
• Glycerol-based Polymers for Biocompatible Surfaces
Marie Weinhart (FU Berlin / Haag Group)
• Evaluation of Topological and Connective Defects in
Tetra-PEG Gel
Yuki Akagi (Univ. Tokyo / Chung Group)
• Dynamic Pattern Formation of Hydrogel-actuated
Polymer Microstructures in Fluid upon pH Change
Lauren Zarzar (Harvard / Aizenberg Group)
• Degradable Shape-Memory Polymers
Marc Behl (GKSS / Lendlein Group)
• A Human Breathing Lung-on-a-Chip
Dan Huh (Harvard / Ingber Group)
• A New Class of Polyglycerol-Based Amphiphiles for
Tailoring the Properties of Carbon Nanotubes
Antonio Setaro (FU Berlin / Reich Group)
October 2, 2010 (Sat.), 14.00 - 16.00
• Droplet-Based High-throughput Biology: Sequencing,
Screening and the Directed Evolution of Novel Organisms
Adam Abate (Harvard / Weitz Group)
• Design of Artificial Photosynthetic Gels Involving an
Electronic Transmission Circuit
Kosuke Okeyoshi (Univ. Tokyo / Yoshida Group)
• Trapping Single Molecules at the One-Nanometer Limit
Alex Fields (Harvard / Cohen Group)
• Spontaneous Formation of Nano-sized Polyion Complex
Polymersomes (PICsomes) and Their Properties
Yasutaka Anraku (Univ. Tokyo / Kataoka Group)
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Young Investigator Presentations
• Nanoparticle-Targeting to Ischemic Tissue for Imaging
and Therapeutic Angiogenesis
Kim Jaeyun (Harvard / Mooney Group)
• Smart Nanostructured Materials Made of Polymer
Nanofibers and Carbon Nanotubes for Neural Implant
Applications
Izabela Firkowska (FU Berlin / Reich Group)
• Bionanotubular Machines from Molecular Chaperones:
A New Paradigm for ATP–Responsive Protein Delivery
Shuvendu Biswas (Univ. Tokyo / Aida Group)
• Intracellular Protein Delivery with Dendritic
Molecular Glue
Kou Okuro (Univ. Tokyo / Aida Group)
• Multifunctional Dendritic Polyglycerol Architectures for
Drug and Dye Delivery
Marcelo Calderon (FU Berlin / Haag Group)
• Combination of Chondroitin Sulfate and Polycation-based
Gene Carriers for Alleviation of Membrane Damage
Satoshi Uchida (Univ. Tokyo / Kataoka Group)
• High Resolution Detection of Single Nanoparticles in
Human Skin and Single Cells by X-ray Microscopy
Christina Graf (FU Berlin / Rühl Group)
• Nanocarrier and Tissue Engineering - New Treatment
Options for Severe Skin Diseases
Sarah Küchler (FU Berlin / Schäfer-Korting Group)
9
Freie Universität Berlin was established in 1948 and is located in
the residential garden district of Dahlem in southwestern Berlin.
Freie Universität Berlin is a leading research institution. It is one
of nine German universities that has been successful in obtaining
all three funding lines in the federal and state Excellence Initiative,
thereby receiving additional funding for its institutional future
development strategy. Freie Universität can thus take its place as
an “international network university” in the global competition
among universities. Its future development strategy is focused
around three strategic centers: for cluster development, international cooperation, and graduate studies. Research projects are
being developed and assessed within five major focus areas – Area
Studies, Humanities, Nanoscale Functinal Materials, Plant Sciences,
and Urban Earth Studies. Charité University Medicine Berlin, a joint
coorporation of Freie Universität and Humboldt-Universität, is the
largest medical school in Europe.
Currently, Freie Universität has over 130 partnerships with scholarly institutions worldwide. About 600 foreign scholars contribute to
the diversity in research and teaching. Of its approximately 32,000
students in over 100 subject areas, 16 percent come from abroad.
The Focus Area Functional Materials at the Nanoscale (Nanoscale) focuses on advanced interdisciplinary research on materials properties of nanoscale systems. The systems we are interested
in range from nanotubes and nanoparticles over macromolecules
to peptides and proteins.
The Center for Supramolecular Interactions (CSI) focuses on
noncovalent intermolecular interactions and the design of new
clinical therapies and molecular devices.
The Freie Universität Berlin is the speaker university of the Collaborative Research Center (SFB) 765, with its research of ‘‘Multivalency as chemical organisation and action principle: New architectures, functions and applications“. Both, life and materials science
benefit greatly from a comprehensive understanding of multivalent interactions.
www.fu-berlin.de/en/index.html
www.nanoscale.fu-berlin.de
www.fu-berlin.de/sites/en/csi/index.html
www.sfb765.de
10 | Trilateral Symposium • Berlin, October 2010
Harvard University
Harvard University was established in 1636 and consists of 2,100
faculty members and more than 10,000 academic appointments in
affiliated teaching hospitals as well as 20,000 students (incl. about
13,600 graduate and professional students). Harvard University is
made up of 11 principal academic units, ten faculties, and the Radcliffe Institute for Advanced Study.
The School of Engineering and Applied Sciences, SEAS, serves
as the connector and integrator of Harvard’s teaching and research
efforts in engineering, applied sciences, and technology. It is closely linked with a variety of multidisciplinary and innovative research
institutes, centers, and initiatives.
The University is part of an integrated partnership called the National Nanotechnology Infrastructure Network (NNIN), comprised
of thirteen user facilities, led by Cornell and Stanford, that provides
opportunities for nanoscience and nanotechnology research.
• BASF Advanced Research Initiative at Harvard University
• Center for Microfluidic and Plasmonic Systems
• Center for Research in Computation and Society
• Initiative in Innovation Computing (archive)
• Kavli Institute for Bionano Science and Technology at
Harvard University
• Materials Research Science and Engineering Center
• Nanoscale Science and Engineering Center
• The Rowland Institute
• Center for Nanoscale Systems
• Harvard Catalyst
• Harvard University Center for the Environment
• Institute for Quantum Science and Engineering
• The Microbial Sciences Initiative
• Wyss Institute for Biologically Inspired Engineering at
Harvard University
www.harvard.edu/index.php
www.seas.harvard.edu
Trilateral Symposium • Berlin, October 2010 | 11
The University of Tokyo
The University of Tokyo was established in 1877 as the first national university in Japan. As a leading research university, the
University of Tokyo offers courses in essentially all academic disciplines at both undergraduate and graduate levels and conducts
research across the full spectrum of academic activity. The University of Tokyo has a faculty of over 4,000 and a total enrollment of
about 29,000, evenly divided between undergraduate and graduate students.
The Center for NanoBio Integration, CNBI, researches the structures and functions of the body on a nanoscale and contributes
to the development of nanomachines and devices in which bioinspired structures and functions are incorporated. It establishes
the intellectual foundation and the interdisciplinary scientific
technological system which explores and reveals the nature of biofunctions on a nanoscale based on nanotechnology and materials
technology. It promotes the construction of an innovative ‘‘nanomedical“ system based on nano-level spatiotemporal bioregulation. Three subthemes related to important nanobio functions are
creation of bioinspired nanomachines, an accurate spatiotemporal
control-type biosensing system, and nanotechnology and materials technology for nanoscale cell therapy.
www.u-tokyo.ac.jp/index_e.html
http://park.itc.u-tokyo.ac.jp/CNBI/e/index.html
Berlin-Brandenburg Center for Regenerative
Therapies
Within the Charité Universitätsmedizin Berlin the Berlin-Brandenburg Center for Regenerative Therapies, BCRT, is implemented as an independent, interdisciplinary research center pooling
national and international expertise for the development of new
regenerative therapies for clinical application. It consists of a strategic alliance between Charité Universitätsmedizin Berlin and the
Helmholtz Association of German Research Centers, represented
by Max-Delbrück-Center, Berlin-Buch and GKSS, Center of Biomaterial Development in Teltow.
The BCRT has a highly interactive research program based on a
consortium of internationally acknowledged experts in both basic
and clinical science. The program comprises work in three medical
research fields linked to overlapping platforms on basic, bioengineering, and translational research. The Center of excellence has a
particular emphasis on research and clinical programs related to
musculoskeletal and immunological applicationsas well as regenerative therapies for the cardiovascular system. One Focus is the
endogeneous regeneration though the application of cells, biological factors, and biomaterials.
http://bcrt.charite.de
Center for Biomaterial Development of the
Helmholtz Society
The research at the GKSS Center of Biomaterial Development
in Teltow is focused on the development of innovative, polymerbased biomaterials for medical applications. The spectrum of the
product developments extends from different types of plastics
that can be used in regenerative medicine and in the field of tissue
engineering to active implants for minimally invasive surgery, adsorber materials for filter systems, apheresis or other detoxification
processes for use on bodily fluids outside the body, and intelligent
drug delivery systems for the pharmaceutical industry.
The Research of the Center for Biomaterial Development is split
into the following departments: Active Polymers, Interface, Polymer Technology, Biomimetic Materials, Biocompatibility, BCRT /
Biointerface Engineering and Polymerphysics.
www.gkss.de/institute/polymer_research/structure/teltow/index.
html.en
Max Planck Institute of Colloids and
Interfaces
The Max Planck Institute of Colloids and Interfaces, MPI-CI, was
established in 1992. Research in Colloid and Interface Science is
covered by the following Departments: Biomaterials, Biomolecular
Systems, Colloid Chemistry, Interfaces as well as Theory and BioSystems. Current research topics are polymeric films, membranes,
microcapsules, organic and inorganic nanostructures, biomineralization, nano- and microreactors, molecular motors and filaments
as well as chemistry and biology of carbohydrates. Biomimetic research is at the core of the Institute’s activity. A common goal is
to learn from nature how to build hierarchical materials or active
systems with new functionalities with adaptive, self-healing, and
self-assembling properties.
The Department of Biomaterials focuses on interdisciplinary research in the field of biological and biomimetic materials. Research
groups deal with “understanding” the mechanical properties of
biological materials and their adaptation to external stimuli, as
well as with more applied topics, relating to the development of
new materials, on the one hand, and to medical problems in bone
research, on the other. One group is dedicated to the development
of a new micro-focus beamline for scanning x-ray scattering applications at the „BESSY synchrotron“ in Berlin.
www.mpikg.mpg.de/english/cont_issues/news/index.html
Wyss Institute for Biologically Inspired
Engineering
The Wyss Institute Harvard, named after Hansjörg Wyss, focuses
its research and development efforts on six Enabling Technology
Platforms to create and translate new bioinspired materials and
devices into products. These Platforms are teams of Institute faculty, students, fellows and expert research scientists and engineers
with extensive industrial experience, who develop new technologies necessary to advance bioinspired material and device development. The Institute’s initial Enabling Technology Platforms are:
Adaptive Architecture, Anticipatory Medical Devices, Bioinspired
Robotics, Biomaterials Evolution, Biomimetic Microsystems and
Programmable Nanomaterials.
http://wyss.harvard.edu/
Scientists
Prof. Dr. Takuzo Aida
Department of Chemistry and Biotechnology, School of Engineering,
The University of Tokyo, 7-3-1 Hongo,
Bunkyo-ku, Tokyo 113-8656, Japan
[email protected]
http://macro.chem.t.u-tokyo.ac.jp
Self-assembly of π-conjugated molecules; photo, bio, and supramolecular chemistry of dendrimers; soft electronic materials including liquid crystalline semiconductors; new environmentally
friendly materials mostly composed of water; stimuli-responsive
molecular and biomolecular machines
Prof. Dr. Joanna Aizenberg
Amy Smith Berylson Professor of Materials Science; Professor of Chemistry and
Chemical Biology; School of Engineering
and Applied Sciences; Wyss Institute for
Biologically Inspired Engineering; Harvard University
School of Engineering and Applied Sciences, 29 Oxford St, Pierce 229
Cambridge, MA 02138, USA,
(617) 495-3558,
[email protected]
www.seas.harvard.edu/aizenberg_lab
http://wyss.harvard.edu/viewpage/118/joanna-aizenberg
Biomaterials, materials science, biomimetics, self-assembly, nanofabrication, bio-optics, hybrid materials, biomineralization, control
of crystallization, surface science and bio-mechanics
Scientists
Prof. Dr. Ung-il Chung / Yuichi Tei
Department of Bioengineering, School
of Engineering, The University of Tokyo
Tei/Chung-Sakai Laboratory, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, JAPAN
[email protected]
www.bioeng.t.u-tokyo.ac.jp/index_e.
html
www.tetrapod.t.u-tokyo.ac.jp/member_
english.html
Development of intelligent implant devices with regenerationinducing capacity. Regenerative medicine / tissue engineering,
focus on signals and scaffolds. Development of monitoring
systems for cell differentiation using cell-based sensors. Development of novel manufacturing methods for scaffolds. Fabrication of
intelligent biomaterials by integration with DDS.
Prof. Dr. Adam E. Cohen
Assistant Professor of Chemistry and
Chemical Biology and Physics
Harvard University
Depts. of Chemistry and Chemical Biology and of Physics, Harvard University
12 Oxford Street
Cambridge, MA 02138
(617) 496-9466
[email protected]
www2.lsdiv.harvard.edu/labs/cohen
Developing and applying physical tools for studying molecules
and cells
Current interests: Trapping single molecules in solution;
single molecules in nanostructures; transport through hydrogels;
magnetochemistry; optical chirality; optical imaging of membrane
potential.
Scientists
Univ.-Prof. Dr.-Ing. Georg N. Duda
Julius Wolff Institute and Center for Musculoskeletal Surgery Berlin-Brandenburg Center for Regenerative Therapies,
Univer Speaker SFB 760 and GSC 203
Augustenburger Platz 1
13353 Berlin, Germany
+49 30 450 559079
[email protected]
Biomechanical aspects of bone and soft tissue healing and regeneration, development of new methods to document healing
progress in experimental and clinical settings. Goal is to achieve
a broader understanding of the mechanical boundary conditions
and how they drive and influence regeneration and healing of
bone and other musculoskeletal tissues. In particular, the effect of
physical effects on the endogenous regeneration pathway is evaluated using biomechanical, histological and molecular biological
methods.
Prof. Dr. Peter Fratzl
Director Max Planck Institute of Colloids
and Interfaces, Potsdam
Hon. Professor at Humboldt University
Berlin and Potsdam University
MPI Colloids and Interfaces, Department
of Biomaterials Research Campus Golm,
14424 Potsdam
[email protected]
www.mpikg.mpg.de/bm
Bio-mimetic materials research, structure function relation in biological materials, mechanical properties and numerical modeling
of composite materials, solid-state phase transformations, bone
and mineral research with biomedical applications (such as bone
material quality in osteoporosis treatment or materials aspects in
bone regeneration)
Scientists
Prof. Dr. Takashi Funatsu
Professor of Biophysics
Laboratory of Bioanalytical Chemistry,
Graduate School of Pharrmaceutical Sciences, The University of Tokyo
The University of Tokyo, 7-3-1, Hongo,
Bunkyo-ku, Tokyo 113-0033, Japan
[email protected]
www. f.u-tokyo.ac.jp/~funatsu
Single molecule biophysics, Analytical Chemistry
Current interests: Elucidating the molecular mechanism of biomolecular machine, such as a molecular chaperonin, single molecule imaging of processing and transport of mRNA in a living cell,
development of micro/nano devices to analyze bio-molecular interactions
Prof. Dr. Rainer Haag
Chair Professor of Organic and Macromolecular Chemistry
Department of Chemistry and Biochemistry, Freie Universität Berlin
Freie Universität Berlin, Institut für Chemie und Biochemie, Takustr. 3, 14195
Berlin
[email protected]
www.polytree.de
Antifouling surfaces, functional dendritic architectures, nanocarriers for drug/dye/RNA delivery, multivalent nanoparticles
Current interests: Supramolecular self-assembly of dentritic amphiphiles and guest encapsulation understanding of multivalent
interactions on a macroscopic level, water soluble dendri-perylene functionalized carbon nanotubes as supramolecular NIR light
sources
Scientists
Prof. Dr. Joachim Heberle
Professor of Experimental Molecular
Biophysics
Freie Universität Berlin, Institut für Experimentalphysik, Arnimallee 14, 14195
Berlin, +49 (30) 8385 6161
[email protected]
www.physik.fu-berlin.de/einrichtungen/ag/ag-heberle
Time-resolved vibrational spectroscopy, photosensory and photosynthetic processes, membrane proteins, protein-protein and protein-lipid interactions, signal transduction, bioelectrochemistry,
molecular biophysics, ion and electron transfer, respiration, surface
structuring and functionalization, biosensors & bioanalytics.
Prof. Dr. Donald Ingber
Professor of Bioengineering, Harvard
School of Engineering and Applied Sciences; Judah Folkman Professor of Vascular Biology, Harvard Medical School
and Children‘s Hospital Boston; Member
of the Kavli Institute for Bionano Science
and Technology; Founding Director,
Wyss Institute for Biologically Inspired
Engineering at Harvard University
Children‘s Hospital Boston, 300 Longwood AvenueBoston, MA 02115-5737
[email protected]
www.seas.harvard.edu/directory/ingber
wyss.harvard.edu/viewpage/121/donald-e-ingber
www.childrenshospital.org/research/ingber/
Cell and tissue engineering, control of tissue morphogenesis, angiogenesis and cancer research, systems biology, and nanobiotechnology
Scientists
Prof. Dr. Kazuhiko Ishihara
Head of the Department
Department of Materials Engineering
Graduate School of Engineering
The University of Tokyo
7-3-1 Hongo, Bunkyo-ku, Tokyo 1138656, Japan
[email protected]
www.bioeng.t.u-tokyo.ac.jp/english/faculty/members/ishihara.html
www.mpc.t.u-tokyo.ac.jp/eng/index.html
Biomaterials and biointerfaces, bioinspired polymers and their
biomedical functions, phospholipid polymers and their application for biomaterials; interaction between cell and polymer
materials; polymeric membranes with permeability for proteins;
stimuli-responsive polymer materials; bio-inspired polymer gels;
stabilization of bioactive substances in aqueous solution with
phospholipid polymer
Dr. Keiji Itaka
Associate Professor of Division of Clinical
Biotechnology,
Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo
7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.
113-0033
[email protected]
www.bmw.t.u-tokyo.ac.jp/english/index.html
DDS, Gene delivery, biomaterials, regenerative medicine, orthopedic surgery
Current interests: Biocompatible nanomicelle-type gene carrier for
safe and sustained gene expression, and its applications for tissue
regeneration and chronic diseases
Scientists
Prof. Dr. Kazunori Kataoka
Director, Center for NanoBio Integration
Professor, Department of Materials Engineering, Grad. School of Engineering
Professor, Center for Disease Biology and
Integrative Medicine, Graduate School
of Medicine,
The University of Tokyo, 7-3-1, Hongo,
Bunkyo-ku, Tokyo, 113-8656 Japan
[email protected]
www.bmw.t.u-tokyo.ac.jp
Nanocarriers for drug and gene delivery, polymeric micelles and
vesicles, smart polymeric materials, materials for regenerative
medicine
Current interests: Development of new polymeric nanocarrier systems, especially block copolymer micelles and vesicles, for drug,
gene, and oligonucleotide delivery. Plasmid DNA packaging for
proper gene transfection.
Prof. Dr. Andreas Lendlein
Director, Institute of Polymer Research,
GKSS Research Centre Geesthacht
GmbH, Teltow (Helmhotz-Society)
Member of the Board of Directory of the
Berlin-Brandenburg Centre of Regenerative Therapies (BCRT), Campus Virchow
Charité and member of the medical
faculty of Charité, Universitätsmedizin
Berlin, Full Professor, Materials in Life
Sciences, Institute of Chemistry and Institute of Biochemistry and Biology, University of Potsdam, and Professor, Institute of Chemistry, Freie Universität Berlin
Institute of Polymer Research, GKSS Research Centre
Kantstrasse 55, 14513 Teltow, Germany
[email protected], http://biomaterials.gkss.de
Macromolecular chemistry, materials science, biomaterial research.
Other fields: stimuli-sensitive polymers, shape-memory polymers,
multifunctional materials, regenerative medicine
Scientists
Prof. Dr. David J. Mooney
Robert P. Pinkas Family Professor of Bioengineering, Harvard University
Pierce Hall 319
The Mooney Lab: Laboratory for Cell and
Tissue Engineering
[email protected]
www.seas.harvard.edu/mooneylab
wyss.harvard.edu/
Design of new biomaterials that regulate the gene expression of interacting cells for tissue engineering and drug delivery.
Current projects focus on therapeutic angiogenesis, regeneration of
musculoskeletal tissues, and cancer therapies.
Prof. Dr. Gerhard Multhaup
Professor of Biochemistry
Head of the Department of Biochemistry
at the Free University of Berlin
Head of the group ‘‘Biochemistry of Neurodegenerative Diseases’’
Freie Universität Berlin, Institut für Chemie und Biochemie, Thielallee 63, 14195
Berlin
[email protected]
chemie.fu-berlin.de/biochemie/agmulthaup/Prof-Multhaup.html
Biochemistry of neurodegenerative disorders
Current interests: Structural biology and functional aspects of
key proteins involved in Alzheimer disease, organization and
dynamics of protein-cofactor complexes and preventive, diagnostic
approaches.
Scientists
Prof. Dr. Stephanie Reich
Department of Physics
Arnimallee 14, 14195 Berlin,
+49-30-838-56232
[email protected]
Physics of nanostructures. Properties of
systems with dimensions that are in the
nanometer range in comparison to those of solid-state bodies, on
the one hand, and molecules, on the other. Optical spectroscopy
and numerical simulation with ab initio and empirical models. Assigning the atomic structure of carbon nanotubes using Raman
scattering; examining physical processes such as the interactions
between charge carriers or between electrons and vibrations in
one-dimensional systems.
Prof. David Weitz
Mallinckrodt Professor of Physics & Applied Physics
Director, Harvard Materials Research Science & Engineering Center
Co-director, BASF Advanced Research
Initiative at Harvard
Co-director, Harvard Kavli Institute for
Bionano Science & Technology
Department of Physics and School of Engineering and Applied Sciences,
Harvard University, Pierce Hall, 29 Oxford St., Cambridge MA,
01238 USA.
[email protected] , www.seas.harvard.edu/weitzlab/
Soft condensed matter physics
Current interests: Materials properties of soft matter, biophysics
of biopolymer networks and cells, formulation of new structures
using microfluidic techniques, biotechnology
Scientists
Dr. Kenichi Ataka
Experimental Molecular Biophysics,
Department of Physics, Freie Universität
Berlin, Arnimallee 14, 14195 Berlin
[email protected]
www.physik.fu-berlin.de/einrichtungen/ag/ag-heberle/index.html
Functional study of enzymes by using
surface analytical technique, Vibrational
spectroscopy of solid/liquid interfaces,
Electrochemistry. Current interest: time-resolved vibrational spectroscopy of membrane protein monolayer
Dr.Takamasa Sakai
Assistant Professor
Department of Bioengineering,
Graduate School of Engineering,
University of Tokyo, 7-3-1 Hongo,
Bunkyo-ku, Tokyo, Japan
[email protected]
www.tetrapod.t.u-tokyo.ac.jp/
Polymer chemistry, polymer physics
Current interest: polymer networks formed from star polymers
Dr. Eduardo A. Silva
Mooney Group, Harvard
[email protected]
[email protected]
www.seas.harvard.edu/mooneylab/
members.php?name=silva
Multivalent material systems for treating ischemia and tissue regeneration
(e.g. coronary infarct, peripheral arterial
disease, wound healing and diabetes), nanoscale injectable polymeric systems, capable of recruiting progenitor and mature cells
for angiogenesis
Travel Information
Travel Information
Arrival by airplane
From airport Tegel (travel time is ca. 60 minutes)
• Take bus X9 or 109 (outside the main entrance of the airport building) direction Zoologischer Garten
• Get off at Jakob-Kaiser-Platz (subway station) and change
to subway
• Take subway line (U-Bahn)) U7 direction Rudow. Get off at
subway station Fehrbelliner Platz and change subway lines.
• Take southbound subway line U3 direction Krumme Lanke.
• Get off at Dahlem Dorf.
By TAXI: It takes about 20 minutes and cost ca. 20 €.
From airport Schönefeld (travel time is ca. 80 minutes)
• Take bus 171 or walk to S-Bahn (train) station Schönefeld
(10 minutes walk from the arrival hall).
• Take line S9 direction Spandau.
• Get off at Treptower Park.
• Change to the circle line S41 traveling west and get off at
Heidelberger Platz.
• Change to subway line U3 direction Krumme Lanke.
• Get off at station Dahlem Dorf.
By TAXI: It takes about 30 minutes and cost ca. 40 €.
Exit the underground station and follow the detailed plan on the
back of this booklet.
Public transportation
Berlin and the surrounding areas are divided into three fare zones
(A,B and C). Tickets are avaiable for two fare zones (AB or AC) or
the entire zone (ABC) and can be used for all subway lines, S-Bahn/
regional trains and buses.
An AB-ticket is valid within the Berlin city limits and Tegel Airport.
A BC-ticket is valid in the areas outside of the S-Bahn circle and
in the surrounding areas (Schönefeld Airport is located in zone
C). One ticket cost 2,10 - 2,50 € and is valid for two hours (can be
used in one general direction, change of lines permitted). There
are also 4 single tickets for 8 €, group tickets or day ticket available. For further information, see: www.bvg.de/index.php/en/index.
html
Venue and Accomodation
Venue
The symposium will take place at the
Institut für Chemie und Biochemie
Takustr. 3
14195 Berlin
www.chemie.fu-berlin.de/fb/general_en.html
subway stop: Dahlem Dorf
Main lecture hall and seminar room 12.12
are both on the ground floor.
Accommodation
Seminaris CampusHotel
Science & Conference Center
Takustrasse 39, 14195 Berlin
Tel. +49(0)30 - 557797-0
[email protected]
www.seminaris.de/berlin
Evening Dinners
Seminaris Campus Hotel
Takustr. 39
14195 Berlin
Alter Krug
Königin-Luise-Straße 52
14195 Berlin
030-84319540
Historische Weinstuben
Poststraße 23
10178 Berlin
030-2424107
subway stop: Klosterstraße
Information
Contact / Information
Scientific Program
Prof. Dr. Rainer Haag
Institute for Chemistry and Biochemistry
Takustraße 3
D-14195 Berlin
+49 30 838-53358
[email protected]
Local Organization
Dipl.-Chem. Achim Wiedekind
FU-Berlin, IOC, Takustr. 3, R. 32.03
+49 30 838-55462
[email protected]
Dr. Pamela Winchester
FU-Berlin, IOC, Takustr. 3, R. 32.12
+49 30 838-53358
[email protected]
Sponsors
•
•
•
•
Center for International Cooperation, FU Berlin
Center for Nanoscale Functional Materials, FU Berlin
The University of Tokyo, Todai, Japan
WYSS Institute, Harvard University, USA
Pictures
Pictures on the title and last page were taken from FU Berlin sources, copyright FU Berlin / David Ausserhofer / Rainer Haag
Impressum
Published by the Center for Nanoscale Functional Materials,
Editor: Dipl.-Chem. Achim Wiedekind
Typesetting and Layout: Dipl.-Chem. Achim Wiedekind
Printing: Sprintout Digitaldruck GmbH, Berlin, October 2010

C o n f e r e n C e B o o k l e t - Nanoscale

Transcription

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