annual report 2013 - Univerzita obrany

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UNIVERSITY OF DEFENCE
FACULTY OF MILITARY HEALTH SCIENCES
ANNUAL REPORT
2013
HRADEC KRÁLOVÉ
CZECH REPUBLIC
Faculty of Military Health Sciences
Hradec Králové
EDITORIAL NOTES
Dear Reader:
This publication presents the main activities of the Faculty of Military
Health Sciences Science of the University of Defence in Hradec Králové.
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The 22 Annual Report includes the principal research and educational
activities of the 9 departments, 1 institute and 1 centre so that it may act as
a basis for internal and external evaluation respectively.
Should you require more detailed information about our Faculty, it is
available on our website http://fvz.unob.cz or http://www.pmfhk.cz.
In case of any suggestions or comments to our activities, do not hesitate
to contact us at the undermentioned address.
Vice-Dean for Research
Prof. Pavel Boštík
[email protected]
Our contact address in different languages is as follows:
Univerzita obrany Brno
Fakulta vojenského zdravotnictví Hradec Králové
University of Defence Brno
Faculty of Military Health Sciences Hradec Králové
Universität der Verteidigung Brno
Wehrmedizinische Fakultät Hradec Králové
Université de la Défense de Brno
Faculté de Médecine Militaire de Hradec Králové
Universidad de Defensa Brno
Facultad de Sanidad Militar Hradec Králové
Universitas Defensionis Brunensis
Facultas Medicinae Militaris Greczreginensis
Třebešská 1575
500 01 Hradec Králové
Czech Republic
CONTENTS
EDITORIAL NOTES ....................................................................................... 3
CONTENTS ................................................................................................... 5
FOREWORD .................................................................................................. 7
INTRODUCTION ............................................................................................ 9
HISTORY ......................................................................................... 9
MAIN AIMS OF THE FACULTY IN 2013 ....................................... 18
STRUCTURE OF THE FMHS ...................................................................... 23
DEAN OF THE FACULTY ............................................................................ 24
DEAN OF THE FACULTY AND HIS DEPUTIES ......................................... 25
MEMBERS OF THE SCIENTIFIC COUNCIL ................................. 26
MEMBERS OF THE ACADEMIC SENATE ................................... 26
MEMBERS OF THE EDUCATION COMMISSION ........................ 27
MEMBERS OF THE EDITORIAL COMMISSION .......................... 28
CENTRE OF ADVANCED STUDIES ........................................................... 29
DEPARTMENT OF COMMUNICATION AND INFORMATION SYSTEMS .. 36
DEPARTMENT OF EPIDEMIOLOGY .......................................................... 38
DEPARTMENT OF FIELD INTERNAL MEDICINE ...................................... 45
DEPARTMENT OF FIELD SURGERY ......................................................... 48
DEPARTMENT OF GENERAL AND EMERGENCY MEDICINE ................ 52
DEPARTMENT OF MILITARY HEALTH SERVICE ORGANIZATION ......... 55
DEPARTMENT OF MILITARY HYGIENE .................................................... 57
DEPARTMENT OF PUBLIC HEALTH ......................................................... 59
DEPARTMENT OF RADIOBIOLOGY .......................................................... 62
DEPARTMENT OF TOXICOLOGY .............................................................. 65
INSTITUTE OF MOLECULAR PATHOLOGY .............................................. 68
VIVARIUM .................................................................................................... 74
VISITORS TO THE FACULTY OF MILITARY HEALTH SCIENCES ........... 75
VISITS ABROAD .......................................................................................... 75
WORKSHOPS, COURSES, RESIDENCIES AT THE FACULTY IN 2013 .. 81
INTERNATIONAL COOPERATION ............................................................. 85
SCIENTIFIC AND RESEARCH ACTIVITIES ............................................... 91
THE REVIEW OF RESEARCH PROJECTS CARRIED OUT AT THE
FACULTY OF MILITARY HEALTH SCIENCES IN 2013 ............................. 95
ARTICLES IN JOURNALS WITH IMPACT FACTOR ................................. 103
ARTICLES IN OTHERS JOURNALS ......................................................... 114
TEXTBOOKS, MONOGRAPHS, ARTICLES IN MONOGRAPHS AND
PROCEEDINGS ......................................................................................... 121
ABSTRACTS IN JOURNALS WITH IMPACT FACTOR ............................. 124
ABSTRACTS .............................................................................................. 126
PRESENTATIONS AND POSTERS .......................................................... 132
INDEX ........................................................................................................ 165
FOREWORD
FOREWORD
The Faculty of Military Health Sciences of the University of Defence
in Hradec Kralove is a centre of medical education and research
in the Czech Army with long-term history in the Czech Republic. The military
medical education began in Hradec Kralove in 1951. The school was
established by an order of the President of the Republic as the Military
Medical Academy, and later a honorary nickname of "Jan Evangelista
Purkyne" was added. Later on, the name was changed to the Military
Medical Research and Training Institute and in 1988 its original name was
used again. In 2004, during professionalization of the army, reorganization
of military education and establishment of the University of Defence, a new
phase of the faculty entitled the Faculty of Military Health Sciences began.
Since 2004 our faculty has been one of the three faculties at the University
of Defence. Presently, the Faculty of Military Health Sciences plays a key
role in military university education with the highest scientific contribution
at the university. After merging with two other originally separated military
faculties, we have created a viable and developing organism emphasizing
strengths of its units. Each faculty covers variety of different tasks
with limited staff and resources. Our role is not only to educate and train all
medical, pharmaceutical and nursing specialists and to keep scientific
excellence, but also to provide a general support to the Military Medical
Service which is influenced by staff cuts and restructuring policy as well.
Primarily, the Faculty provides study in one accredited bachelor`s study
programme (Military Paramedic), three master`s study programmes (Military
General Medicine, Military Dentistry, Military Pharmacy) and eight doctoral
study programmes.
In spite of every year lower financial budget and personal reduction, we
would like to continue and even to increase most of our activities. Our
scientific production rate is the highest at the entire University of Defence.
The Czech (Medical Service) field hospitals are well-known around the world
and there are not so many similar good examples in our Military except
military police and chemical troops. Our approach is different
from the majority of other services. Our training is both long-term and
intensive thus the students gain deeper knowledge and wider skills as well
as awareness of military life. Education, training and research should be
jointed and a pool of excellent professors, scientists and teachers should be
created. But it is a long way to go. The Faculty of Military Health Sciences is
an open body for mutual cooperation with scientists and teachers from all
democratic countries. In spite of changing priorities in the Czech Military, we
have been still dealing with specialization of the Czech Armed Forces
in nuclear, biological and chemical protection and we have been engaged
in many humanitarian and military deployments of military medical services
abroad. Our Faculty will play the key role in this demanding process. We will
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22 Annual Report, 2013 – 7
FOREWORD
guarantee the research and fulfilment of training needs for medical corps,
specialized forces and for some NATO countries. Nevertheless, our primary
concern is to educate and train students and young physicians. This can be
hardly possible without our closest partners, international workmates and
friends.
At present, the Faculty covers the needs of troops concerning medical
professional training in all specializations, medical informatics, science and
research. The Faculty represents an optimal model of education for less
populous medical specialities in close cooperation with Charles University
in Hradec Kralove. The Faculty has educated a lot of specialists not only
at a national, but also (at least) at European level. A lot of important positions
prove it. These positions have been held by former and present faculty
personnel in important international institutions from the NATO Surgeon
General in Europe, through a membership in various NATO, EU, United
Nations Security Council, and World Health Organization boards, European
Centre for Disease Prevention and Control. The Faculty provides and solves
a lot of research projects, it has its own complex laboratory technologies
for scientific work, above all within the sphere of life force protection against
NBC agents. The scientific results are published in many respected
international journals such as the Lancet.
The very fact that the Faculty has survived all reforms, reorganization and
other changes demonstrates its uniqueness, high educational, professional
and research level. That could not be achieved without close cooperation
with other scientific and educational workplaces. Not all universities can be
proud of so close collegial relationship as we have with the Medical
and Pharmaceutical Faculties of Charles University, the University of Hradec
Kralove, the Faculty of Health Studies in Pardubice, the Faculty Hospital
in Hradec Kralove and the Military Medical Agency. In 2012, the Central
Military Hospital in Prague was declared the Military Faculty Hospital. This
medical facility, with which we have cooperated very closely, creates a good
background for military medical practice of our students. Personally, I value a
cooperation with representatives of the city of Hradec Kralove, thanks to
which the Faculty has an excellent reputation at city public. I am pleased that
this collaboration continues.
I, as a new dean, appreciate my predecessors of the faculty management
that they have sustained the tradition of highly educated military doctors and
pharmacists. Being elected the FMHS dean I consider the apex of my
medical and military career. It is an honour to get an opportunity to contribute
from such a top position to military pre-graduate and post-graduate
education within next several years.
Dean of the Faculty of Military Health Sciences
COL Assoc. Prof. Jiří Páral, M.D., Ph.D.
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HISTORY
INTRODUCTION
HISTORY
The Purkyně Military Medical Academy has been a long-term educational
and scientific centre of the Czech Army Medical Service. There has been
a very long history of systematic education of military medical personnel
in our country. Its beginnings lie, as in many European countries, in the 18th
century. Large, permanent armies were being built and the military medical
service became a normal part of these armies. In 1776 the War Council
of the Vienna Court issued an administrative order which definitely prohibited
the employment of field surgeons in the armed forces who had not studied
anatomy and who had not had their knowledge officially examined. This can
be considered the beginning of organized education of military medical
personnel in our country. Six-month courses were organized for field
surgeons at the Garrison Hospital in Gumpendorf near Vienna.
The fundamental milestone in the “Austrian“ stage was, however, in 1785
with the establishment of the Military Medical (Surgical) Academy named
the Josephinum after its founder, the enlightened monarch and father
of many political and social reforms, Emperor Joseph II. He saw the mission
of the school as fulfilling these tasks:
•
•
•
education of qualified military surgeons (physicians)
creation of a learned society for research in medical science
creation of a permanent field sanitary commission for solving
questions concerning combat casualty care.
A number of renowned physicians of Czech origin significantly
contributed to nearly 90 years of the school´s history.
The foundation of the independent Czechoslovak Republic in 1918 meant
at the same time the creation of a democratic army. The basic element
of career military physician training was represented by the Military Medical
School. Its establishment was the result of a decision by the Czechoslovak
Republic government which by its resolution of 25 June 1926 defined
the principles of recruiting professional medical and pharmaceutical
personnel to the army. The Military Medical School provided professional
training for military physicians and further qualification growth
for the performance of higher command functions in the military medical
service tructure.
The development of the Czechoslovak Military Medical Service in our
country was interrupted by the Second World War. When the army was
disbanded a number of physicians and medical students participated
in foreign and domestic resistance. The largest number of them were
concentrated in England. The British government permitted medical students
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HISTORY
to complete their studies at British universities. They graduated from Oxford
University. The Czechoslovak Military Hospital was created at London
Hammersmith Hospital. A few courses of the Medical and Pharmaceutical
Reserve Officer School were taught in Leamington and Walton-on-the-Naze
where the Czechoslovak Brigade´s out-patients´ department was situated.
Thus, the tradition of the Czechoslovak military medical educational system
maintained its continuity.
In 1945 the pre-war practice of recruiting professional personnel
to the Military Medical Service was rebuilt. The Military Medical School
in Prague was renowned. At the same time tendencies referring
to the practice of some medical services of the world´s leading armies which
required the establishment of an independent military medical university
were increasing. The results of the Second World War and the growth of new
knowledge in the field of medicine and especially military medicine played
a significant role in this.
In 1951 a new period began in the development of the Czechoslovak
military medical educational system. This period has been permanently
connected with Hradec Králové for 55 years. Rapid establishment
of the Military Medical Academy (MMA) was possible only due to the fact that
it was built on the basis of being a theoretical and clinical part of the Faculty
of Medicine – a branch of Charles University established in 1945. Thanks
to the reputation of its workers, a majority of whom became employees
of the MMA, the school became an educational and scientific centre
of the Czechoslovak Medical Service and within a short time gained a good
reputation both at home and abroad.The MMA has educated a number
of outstanding military medical specialists and the first steps of several
contemporary top specialists of Czechoslovak medicine were connected
with its existence.
Beginning in 1958 and for the next 30 years the military medical system
was transformed into the form of the Purkyně Military Medical Research
and Postgraduate Institute. Research tasks and activities in the area
of further schooling and specialization of military physicians and pharmacists
became a fundamental part of its activity. The main portion of a further basic
task of the school – the pregraduate training of future military physicians –
was taken over by the renewed Faculty of Medicine of Charles University
in Hradec Králové. The development of mutual cooperation between these
two partner schools, to which the Faculty of Pharmacy of Charles University
in Hradec Králové joined in 1976 as a significant guarantee of the education
of military pharmacists, has become a part of the military medical system.
In 1988 the school changed its name to the Purkyně Military Medical
Academy which, institutionally, reflects more precisely the wide variety of its
activities.
In November 1989, the school entered a qualitatively new period
of development. It has passed through a transformation which has basically
changed some military-professional teaching programmes, the organizational
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HISTORY
structure of the school, personnel support, the composition of the educational
staff and so on.
The Academy has been included in the new university educational
system and since 1993 (origin of the Czech Republic) has served
as a training centre for Czech Army medical professionals. It has trained
nearly 2600 military surgeons, dentists, and pharmacists till now.
Some special activities have become a main part of the school´s
activities. The humanitarian role of the Military Medical Service and
the Military Medical Academy personnel in the present foci of conflicts
in the world without doubt rank among them. As early as 1991
an independent Czechoslovak NBC battalion was sent to the Gulf. In 1994
a further tradition was established – regular operation of military medical
personnel in peace-keeping missions in the territory of the former
Yugoslavia. The 6th Field Hospital is known to the public for its operations
abroad, first in the former Yugoslavia and later in Albania, and then in Turkey
following the earthquake in that country. In 2002 members of the Czech
Army Military Medical Service were employed in the ISAF mission
in Afghanistan. From May to October it was the 6th Field Hospital. Then this
mission was taken over by the 11th Field Hospital which completed its
operations at the end of 2002. Professional training and personal
acquaintance of both field hospitals personnel before their departure abroad
has been traditionally carried out at the Purkyně Military Medical Academy.
Some employees of the Purkyně Military Medical Academy are
representatives at international non-governmental institutions and
in the positions of UN and NATO experts and advisers. The highest position
within the NATO Allied Command Europe Medical Service was held by
Brigadier-General Assoc. Prof. Leo Klein, M.D., CSc. He remained in this
position until September 2002 when he completed his period of service.
Since December 2002 he has been Surgeon General of the Czech Army
Medical Service. He is known to the public for his work at the Department of
Field Surgery at the Purkyně Military Medical Academy and at the Surgical
Department of the Teaching Hospital in Hradec Králové.
COL Assoc. Prof. Roman Prymula, M.D.,CSc., Ph.D. has been elected
the new Rector of the Purkyně Military Medical Academy. He officially
assumed this position on October 1, 2002.
The Academy continues to be a centre for integrated education and
scientific research activity ensuring educational and research activities of all
kinds and degrees for the training of military medical professionals. In the
future its aim is to remain a modern university institution fully comparable
with similar facilities and standards in other NATO countries.
The year 2003 was significant with regard to different opinions on the
reform of the Czech Republic Armed Forces. The initially proposed
conception was reevaluated in the wake of the reform of public finances
which was enforced by the Government. Therefore financial sources were
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HISTORY
redistributed and reduced. There were new efforts to establish an economic
army structure. The Czech Republic Government Resolution no. 1154 of 12
November 2003 entitled “The Conception of the Professional Czech Republic
Army Development and Mobilization of the Czech Republic Armed Forces
Modified According to Financial Sources“ has become the final document
respecting NATO general interests.
Academy life was significantly affected by the mission of the Czech
Republic Army 7th Field Hospital to Iraq. (The hospital followed with activities
of the Czech Chemical Protection Contingent in Kuwait). Transport
of soldiers and material began on 18 April 2003. Basra, in southern Iraq, was
appointed the final destination. In September 2003 a personnel rotation was
carried out and the hospital finished its activities in December 2003. Our
Academy significantly supported the deployment of the 7th Field Hospital
through its personnel, organizational activities, professional education and
training.
One of the most important preconditions of transformation of the Czech
Republic Army to the fully professional system, is a reorganization of military
school system. In the year 2004, merital changes were done in this area.
On the basis of amalgamation of the Military School of Ground Forces
in Vyškov, the Military Academy in Brno and the Purkyně Military Medical
Academy in Hradec Králové there was established the University of Defence
in Brno. It comprises three faculties – the Faculty of Military Technology,
the Faculty of Economics and Management, the Faculty of Military Health
Sciences and three independent university institutes. Act No.214/2004 of the
Code makes up the legal framework of a new legal subject which
at the same time identified the date of establishing the University of Defence
on 1 September 2004. Brig Gen Assoc. Prof. Ing. František Vojkovský, CSc.
became the Rector of the University of Defence. The University of Defence
was oficially opened with a solemn inauguration on 8 October 2004.
After the transformation of the Purkyně Military Medical Faculty into the
Faculty of Military Health Sciences (seated still in Hradec Králové), the basic
functions and tasks of the school focused on a specialized training
of the Czech Army medical officers and on research work in the area
of military health service have been saved. However, number of school
employees was cut down.
A new official name of our school is: University of Defence, Faculty
of Military Health Sciences in Hradec Králové. A new dean of our school
became the former rector of school COL Assoc. Prof. Roman Prymula, M.D.,
CSc., Ph.D., on the basis of new academic bodies´ voting.
In the year 2004, Czech Republic Army officers carried out their
assignments of different forms in peacekeeping missions in Iraq, Afghanistan
and the Balkans. Members of our school were not missing. Specialists
of the Department of Field Surgery played there a principal role. In the frame
of joint operation of multinational forces in Iraq (MNF – Multinational Forces
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HISTORY
Iraq) they fulfilled their tasks at special work places in British military hospital.
Their assistance was highly and positively assessed.
During 2005 the process of establishing the new university subject –
the University of Defence continued with solving the seat and the position
of the Faculty of Military Health Sciences. The Faculty of Military Health
Sciences received an important position in the supreme self-governing body
of the university by electing COL Assoc. Prof. Jiří Kassa, M.D., CSc. as the
Head of the Academic Senate of the University of Defence on 6 October
2005. He works as the Head of the Department of Toxicology and he is
a chief specialist of the Czech Republic Army for toxicology.
The year 2006 was a jubilee year. The staff of the Faculty of Military
Health Sciences of the University of Defence commemorated the 55th
anniversary of the military medical school system in Hradec Králové and its
eighty-year existence in the Czech Republic. This school is an irreplaceable
centre of training and education of military health care professionals of all
branches for the Army of the Czech Republic.The Faculty of Military Health
Sciences of the University of Defence guarantees a good quality
of the solved research tasks for the benefit of the military health service. High
level of the scientific and research activity facilitated the establishment
of scientific cooperation with NATO and EU partners.
The extent of school activities is very wide. The clinical departments
provide the general public with the health care including special therapeutic
activities. Military health care experts are involved in the integrated
emergency system. The preparation of personnel for humanitarian
and peacekeeping missions is implemented here. The school provides
medical information service, experts reports and language teaching
for the Army of the Czech Republic.
More information about the history and the present state of the military
medical school system and the Faculty of Military Health Sciences
of University of Defence is to be found in the publication “Military medical
school system“, edition: Ministry of Defence, Avis, Prague 2006.
In 2007, intensive activity was typical for all aspects of school life. Let´s
recall the most important: The Faculty of Military Health Sciences University
of Defence participated in the preparation of Czech field hospital contingents
(so far three of them have been sent out), which ensure the health support
of ISAF mission in the region of Kabul in Afghanistan. Some medical
specialists of the Faculty were directly fulfilling the mission assignments
as members of the contingent: MAJ Michal Plodr, M.D., Ph.D. worked
as head doctor of the hospital, MAJ Ivo Žvák, M.D. as head doctor
of operating theatres, and MAJ. Jan Psutka, M.D. worked at the department
of contemporary hospitalization. The main task of the field hospital is
to provide professional health care for the wounded and sick during outside
combat activities, as well as for their short-time hospitalization.
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HISTORY
The public show of scientific and research results is traditionally
an important part of school activities. The climax was the 7th Conference
of the Association of Military Doctors, Pharmacists and Veterinary Doctors
of the Czech Medical Society of Jan Evangelista Purkyně in October, and
the 4th Conference Disaster Medicine and Traumatological Planning
in November 2007. This year´s novelty was a competition for the best
scientific student´s work in doctoral study programmes. The cooperation
with foreign school and scientific partner institutions went on. In this context,
the November visit from the Military Medical Academy Lyon, led by its new
commander General Maurice Vergos, was a remarkable event.
At the end of the year, an important event in school organization
happened: 10th December, COL Prof. Roman Prymula, M.D., Ph.D., was
inaugurated Dean of the Faculty of Military Health Sciences. His clear
election to the leading function is not only appreciation of his personal,
managerial and professional qualities (it belongs to his triumph in March –
obtaining the professorial diploma), but also of the stability and continuity
of the place and role of the Faculty of Military Health Sciences.
Significant features of the activity of the Faculty of Military Health
Sciences, University of Defence, were in the year 2008 the public
acknowledgements which were attributed to the Faculty eminent research
specialists. Already in February, Assoc. Prof. Jiří Bajgar, M.D., D.Sc. was
awarded the Prize of the Rector of the University of Defence for his research
work in 2007. The Scientific Council thus appreciated his extraordinarily large
publishing and lecture activities, besides un-disregardable appraisement
Assoc. Prof. Bajgar gained from the American Society of Toxicology, being
awarded the prestige Astra Zeneca Award. The prize winner significantly
contributed to clarification of the toxic effect mechanism of organophosphorous compounds and to the development of new prophylactic and
therapeutic means against highly toxic nerve paralytic substances.
In May, the above mentioned feature of the activity of the Faculty
of Military Health Sciences, University of Defence converted into a handover
of two letters of appointment of new Czech Universities professors to two
eminent workers of the Faculty. In renowned Prague Carolinum, the letters
were accepted from the hands of the President of the Republic by LTC
Assoc. Prof. Jan Österreicher, M.D., Ph.D. and Assoc. Prof. Jiří Stulík, M.D.,
Ph.D.
The Faculty workers confirmed repeatedly their both research and
organizing capabilities. They became the organizers of many traditional
presentations of scientific work. Large community of epidemiologists
gathered at the end of May among others to worship the memory
of the nestor and military specialist in the field of epidemiology, Professor
Bohumil Ticháček, M.D., D.Sc. (1924–2006) by their active participation
at a conference “Ticháček´s Days of Military Epidemiologists”. Similarly,
in September the Faculty substantially participated in organizing the whole
Republic Conference 4th Hradec Vaccinologists Days.
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HISTORY
A number of talents has been revealed by presentation of students´
research work. Periodic Faculty round of research conference of students,
who work mostly as scientific and teaching staff at the the Faculty
Departments, took place at the end of September. CW2 Veronika Mikusová
and CW2 Pavel Novotný obtained this year’s primacy. The postgraduate
programme students presented their research results immediately
afterwards. Works of authors CPT Karel Šmejkal, M.D., a student
of postgraduate programme Military Surgery and LT Jiří Dresler, Doctor
of Pharmacy, a student of postgraduate programme Molecular Pathology,
were awarded the best.
The international cooperation of military medical schools has been
among the traditional active forms of the school work. The visit of
the delegation of the leadership of partnership school École du Service de
Santé des Armées from Lyon, guided by GEN Francis Huet, School Deputy
Commander, confirmed the trend of continuous cooperation.
At last but not least, the conference of the Association of Military Doctors,
Pharmacists and Veterinary Doctors of the Czech Medical Society of Jan
Evangelista Purkyně has become repeatedly much appraised specialist
forums. This year’s 8th Conference content concerned mostly Disaster
Medicine, Traumatology Planning and Training.
The date of the Conference, the last days of November, seemed
to conclude symbolically the year of noticeable presentation and at the same
time extraordinary acknowledgements of the Faculty research results.
CPT. Zdeněk Šubrt, M.D., Ph.D from the Department of Field Surgery,
a graduate of doctoral study programme Military Surgery, was awarded the
Prize of the Mayor of the Town Hradec Králové for students´ research work
in 2009.
Prof. Aleš Macela, D.Sc. was awarded the Prize of the Rector
of the University of Defence for scientific research in 2008, especially
for excellent results in solving scientific projects in the sphere of protection
against effects of extra dangerous biological agents.
In September 2009 the present Dean of the Faculty COL. Prof. Roman
Prymula, M.D., PhD. became on the basis of selection procedure a director
of the University Hospital in Hradec Králové. The Academic Senate elected
LTC Assoc. Prof. Roman Chlíbek, M.D., Ph.D a new Dean of the Faculty.
The Rector of the University of Defence appointed him as dean on 15th
October 2009.
In the year 2010, Prof. Prymula was awarded as the first author of one
of the best Elsevier’s publications in 2009 for the article: Prymula R., Siegrist
C.A., Chlibek R., Zemlickova H., Vackova M., Smetana J., Lommel P.,
Kaliskova E., Borys D., Schuerman L.: Effect of prophylactic paracetamol
administration at time of vaccination on febrile reactions and antibody
responses in children: two open-label, randomised controlled trials. Lancet.
2009, 374(9698):1339-50. Extraordinary high quality of this publication was
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HISTORY
also confirmed by many other awards during the year 2010: 2009 Kredb’s
Award for original scientific work and the best publication from the Czech
Medical Association of J. E. Purkyne, 2010 prof. Karel Raska’s Award for the
best scientific article published during 2009.
In the year 2011, Assoc. Prof. Kamil Kuca was awarded the Prize
of the Rector of the University of Defence for scientific research in 2011,
especially for excellent results in solving scientific projects in the sphere
of protection against chemical warfare agents.
Prof Stulik´s project entitled Identification of novel Francisella tularensis
targets for subunit vaccine development was supported by the Defence
Threat Reduction Agency, USA for the years 2011–2014. This project is
aimed at development of a subunit vaccine for tularemia. It is focused on (1)
the identification of surface associated or secreted virulence factors from F.
tularensis using immunoproteomic approaches (2) cloning and expression
of these gene products, (3) confirming the role of the selected targets
in virulence, and (4) assessing these proteins as protective antigens
in animal models.
The Central Military Hospital in Prague became the faculty hospital
for the Faculty of Military Health Sciences in 2012.
In January 2013, there was a change at the position of Vice-Dean
for research. When Prof. Ing. Kamil Kuča, Ph.D. holding the position of ViceDean for research left the FMHS, Prof. MUDr. Pavel Boštík, Ph.D. replaced
him.
In February 2013, scientists from the University of Defence, the Faculty
of Military Health Sciences, from the University of Hradec Kralove and
the Centre for Biomedical Research had the best poster presentation at 55th
Czech-Slovak Psychopharmacological Conference held in Spa Jeseník. The
project, the authors of which were Hroudová J., Fišar Z., Raboch J.,
Korábečný J., Kuča K., was entitled "In vitro effects of acetylcholinesterase
inhibitors on monoaminooxidase and NADH-dehydrogenase activity".
In the beginning of May 2013 the Faculty hosted a visit of a Finnish group
of CBRN experts and personnel from various branches involved in rapid
response management of crises. Both sides presented their main interests
during a seminar organized by our Faculty and the Finnish guests were given
a tour of selected facilities. This was one of the examples of developing
cooperation of European countries within the framework of the European
Defence Agency.
In October 2013, the Rector-Commandant of the University of Defence
Brigadier General Bohuslav Přikryl decorated LTC associate professor
Zuzana Kročová with the University Medal for her exceptional efforts and
long-term results achieved in her research work.
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HISTORY
The year 2013 was the election year for the Faculty and the Senate. After
4 years it was time for the academic faculty and students to cast a vote
for the Dean. In election, which was held in June, Col. Assoc. Prof. Jiří Páral,
MD, Ph.D. received the majority of votes and became the new Dean
in October 2013.
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MAIN AIMS OF THE FACULTY IN 2013
The Faculty of Military Health Sciences (FMHS) of the University
of Defence in Hradec Králové is a centre of medical education, training and
research of the Army of the Czech Republic. It entirely covers the needs
of the troops concerning medical professional training in all specializations,
medical informatics, science and research.
1. Education
The main aims of the FMHS in the field of education were as follows:
to provide university-level studies in the subjects of military general
medicine (6 years), stomatology, pharmacy (5 years), administration
and management study (3 years), medical rescue (3 years)
to provide postgraduate study for Ph.D. degree (4 years)
in accredited disciplines:
Epidemiology
Field Internal Medicine
Field Surgery
Infectious Biology
Military Hygiene
Military Radiobiology
Molecular Pathology
Toxicology
Preventive Medicine and Public Health
Protection
Medical Microbiology
According to the needs of the Surgeon General of the Czech Armed
Forces and the Military Medical Service Administration, the Faculty ensures
specialized and lifelong education of doctors, pharmacists and other military
medical service personnel in specified branches of the Act No. 95/2004
of the Code about conditions of receiving professional qualification and
specialized qualification to do a medical profession as a doctor,
a stomatologist, and a pharmacist. It unifies the system of their training
with requirements of EU.
The faculty organizes and provides the training for medical personnel
in active service, doctors, nurses and other medical personnel. The faculty
provides professional refresher courses for medical staff, non-medical staff
and non-medical personnel of field medical units- hospital base and its units
in selected up-to-date topics. It takes part in continued training of doctors and
health care personnel, who are sent to missions abroad as well. Unique
military know-how is attractive for people, who work out of the military health
care sphere. The FMHS provides courses of advanced first aid in the field
not only for Military Medical Service personnel but also for professional nonmedical personnel of Military Police units, reconnaissance and special units
within the frame of the Czech Armed Forces, Rapid Reaction Units
of the Czech Republic Police and the others.
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All soldiers assigned to include into foreign missions take part in extra
courses of advanced first aid. Training of emergency life support in field
conditions is required in medical personnel. The courses BATLS/BARTS
(Battlefield Advanced Trauma Life Support) and BARTS (Battlefield
Advanced Resuscitation Techniques and Skills) for doctors and nurses
or health care personnel are enlarged on the problems of NBC protection
and they become a significant standard not only for the whole medical
service, but also for a lot of other specialists, who take part in foreign
missions.
Other courses concentrate on teaching and training of comprehensive
knowledge necessary for providing medical care within the frame of Disaster
Medicine. The FMHS also provides other teaching and training activities
determined by ”The Plan of Courses and Professional Residencies Training
of the Czech Armed Forces Medical Service“ and ”Notification of Director
of Personal Section of the Ministry of Defence – Teaching Activities
at Military schools and Training Facilities in the Czech Republic and Abroad“.
It participates in medical personnel training of medical and non-medical
specializations under the methodical and professional leadership,
in providing instructors for training of higher cathegories of medical personnel
and in teaching instructors of lower medical specialists training.
2. Scientific and research work
The FMHS of the University of Defence provides and solves research
tasks for the Czech Armed Forces Medical Service. Well assembled
scientific teams focus on individual research tasks using state-of-the-art
technologies. Within the Faculty, complex laboratory technologies
for scientific work are utilized for scientific advancements, which lead to the
impromement of life force protection against NBC agents. The high scientific
level and the achieved results in scientific and research activities of present
teams have enabled to start scientific cooperation with foreign partners.
The FMHS is the only one in the Czech Republic who provides military
research within the sphere of CBRNE issues in NATO and EU.
The high level capabilities and international recognition of the scientific
teams form a solid base for scientific cooperation with partners in NATO
countries, which is financed by the NATO and EU funds. Within the sphere
of the science and research, the FMHS fulfilled strategic purposes of the
Czech Armed Forces transformation by targeting the priorities of the Army
(biological agents, chemical agents, military health care), furthermore it
joined the appropriate institutions and organizational structures of NATO and
EU countries (including drawing financial NATO and EU funds) and it gained
some priority results in these critical areas. From the point of view
of specialization and direction of the Czech Armed Forces, the departments
of the FMHS solve medical issues of biological, chemical and radiation
protection. Previous as well as contemporary scientific work within
the studies focused on medical aspects of the effects of NBC agents
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the main focus of the “Centre of Advanced Studies“. This fully corresponds
with set priorities in the field of scientific and research work of the Army
of the Czech Republic. The military medical service organization and
management, information systems, research activities of clinical and
therapeutic preventive branches represent other important fields of scientific
work.
Many invitations to international symposia and conferences as well
as a number of publications prove that scientific knowledge is used
in education. The FMHS personnel can publish achieved results in research
work, therapeutic preventive activities and in educational activities
in the journal Military Medical Science Letters – the oldest military
specialized journal, which has been published since 1925. As of the last
year, the journal is published fully in English.Together with professional
scientific and pedagogical activities there are also results in lecture and
publication areas. They are a part of evaluation, which is carried out
annually. The faculty is successful in keeping a good level of publication
activities in journals with impact factor and in other national and foreign
journals. This fact enables relatively wide training activities in accredited
doctoral study programmes.
Nowadays (Year 2013) the Faculty participates in 5 projects of Internal
Grant Agency of the Ministry of Health, 3 projects of the Ministry
of Education, Youth and Sports, 5 projects of the Grant Agency of the Czech
Republic, 1 project of the Ministry of Industry and Trade, 1 project
of the Ministry of the Interior of the Czech Republic, 2 projects of European
structural funds and 1 foreign project (DTRA). The total sum of research
grants represents the amount of 18,33 mil. Czech Crowns (approximately
907 000 USD).
Scientific, research and development activities in the field of medical
support include prevention, diagnosis and treatment of sick and wounded.
An integral part of this work is to improve the system of medical equipment
administration and supply support.
Research and development is carried out at 9 departments
(Epidemiology, Field Internal Medicine, Field Surgery, General
and Emergency Medicine, Military Hygiene, Military Medical Service
Organization, Public Health, Radiobiology, Toxicology) and in the Institute
of Molecular Pathology, and the Centre of Advanced Studies.
In 2013, scientific work at the faculty departments, the Institute and
the Centre was focused on CBRNE protection research, prevention
in hygiene and epidemiology, topical problems of field surgery and field
internal medicine, topical problems of organization, management, education
and information science in the Military Medical Service.
The continuous accreditation for proceedings to achieve professorships
for the branches of Hygiene, Preventive Medicine, Epidemiology, Medical
Microbiology, Toxicology, Military Radiobiology, Field Internal Medicine,
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Infection Biology and Molecular Pathology and the accreditation
for habilitation (associate professorship) in the branches of Hygiene,
Preventive Medicine and Epidemiology, Medical Microbiology, Toxicology,
Field Surgery, Military Radiobiology, Field Internal Medicine, Infection
Biology and Molecular Pathology gives the evidence about the excellent level
of achieved results in scientific and research activities of FMHS. In 2013,
there were 12 professors (prof.), 12 associate professors (doc.), 3 doctors
of science (DrSc.), 62 persons with research degrees (CSc., Ph.D.) who
carried out teaching and research tasks.
3. Therapeutic activities
Special therapeutic activities were provided especially at the departments
of Field Internal Medicine, Field Surgery and General and Emergency
Medicine. Close cooperation between these subjects and the health service
establishments in the region were more and more developed. Therapeutic
activities were provided, especially in the field of hematologic intensive care,
traumatology, hepatobiliary surgery, and at the plastic surgery departments
of internal medicine and surgery, at the Teaching Hospital.
4. International cooperation
The main aims of international cooperation of the FMHS were
to exchange scientific, educational and therapeutic information and
to develop working contacts between military medical, medical educational
and research institutions of the NATO and EU countries as well as civilian
medical institutions with educational, defence research and development
programmes. Residency and exchange programmes for numerous students,
doctors and research workers took place at those institutions.
As for study programmes, the Faculty keeps close relations with partner
educational institutions above all in NATO and EU countries. Every year
there are exchanges of not only students but also of pedagogical staff
with the Military Medical Academy (ESSA) in Lyon in France, contacts
in pedagogical sphere are kept with partner schools in Germany
(Sanitätsakademie der Bundeswehr, Munich), the Military Medical Academy
in Sofia, Bulgaria. In the past there were contacts with schools in Lódź
(Poland) and Beograd (Serbia).
5. Expert activities
The membership in work groups for coordination and cooperation
of military medical research and professional training at NATO (COMEDS,
BIOMEDAC, RTA/RTO) and at EDA (European Defence Agency), in work
groups of government experts for the Convention on the prohibition
of biological, bacteriological, and chemical weapons and their destruction
in Geneva and UNO, organizing scientific conferences with international
participation, and solving foreign research projects under the cooperation
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of the FMHS personnel are very important for presentation of international
cooperation results. At the FMHS there are conditions for foreign cooperation
in medical research. The priority still remains in cooperation in the frame
of the Human Factors Medicine of the NATO Research and Technology
Organization and its work groups (TG, WG), cooperation in research projects
with other foreign scientific institutions and participation in projects of 7th EU
General Programme. Our aim is to intensify international cooperation
in NATO focused on scientific support of the armed forces structure.
6. Scientific and educational information services
Scientific and educational information services that support the whole
Medical Service of the Czech Republic Army were provided by
the Department of Information and Communication Technologies. Numerous
literature retrievals, courses, library and printing workshops and other
information services support for students, teachers, scientists,
postgraduates, doctors, nurses and other medical experts were carried out.
7. Foreign missions
The FMHS performed the preparation of health personnel
for humanitarian and peacekeeping missions as in the preceding years.
Within last years FMHS members took part in several foreign missions.
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STRUCTURE OF THE FMHS
STRUCTURE OF THE FMHS
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DEAN OF THE FACULTY
DEAN OF THE FACULTY
COL Assoc. Prof. Jiří PÁRAL, M.D., Ph.D.
In June 2013, the academic faculty and
students took part in the election for the post
of the Dean in June 2013. Col. Assoc. Prof.
Jiři Páral, MD, Ph.D. was elected by a majority of votes and became the new Dean
in October 2013.
Jiří Páral was born on 10 February 1968
in Svitavy, He achieved there his secondary
school qualification. He graduated from
Masaryk University, Faculty of Medicine
in Brno and received the university degree.
After graduation, he worked for a short
period for the Orthopaedic Department of the
hospital in Litomyšl. He served at Pohořelice
infirmary during his compulsory military service. In 1993 he began working
for the Department of Surgery of the Faculty Hospital in Hradec Králové.
In 2001 he was appointed a senior lecturer at the Department of War
Surgery of the University of Defence, Faculty of Military Health Sciences
in Hradec Králové, being later promoted to general surgery team leader and
then to the department head positions. In 2008 he completed the postgraduate studies and acquired the PhD degree in military surgery. In 2012 he
defended his advanced thesis to acquire assistant professor degree
in military surgery. He was elected the Dean of the Faculty of Military Health
Sciences of the University of Defence in 2013.
He has contributed to the undergraduate teaching of surgery
for the Faculty of Medicine, Charles University, Hradec Králové since 1995
and to the undergraduate and postgraduate teaching of military surgery
for the University of Defence, Faculty of Military Health Sciences since 2002.
His international deployment experience includes the positions of chief senior
surgeon for the Czech field hospital in ISAF mission in Kabul, Afghanistan,
in 2002, senior surgeon – consultant for the Shaibah, Iraq, base’s UK
hospital in 2004 and senior surgeon – consultant for the KAIA base French
hospital in Kabul, Afghanistan in 2011. The list of background courses
includes “Leadership in Trauma Disaster Management”, Szolnok, Hungary
(2002), “Battlefield Advanced Trauma Life Support Course”, Hradec Králové
(2002), “American Language Course”, DLI–ELC, Lackland Air Force Base,
San Antonio, Texas, USA (2003), “Training in Laparoscopic and Abdominal
Surgery”, Madigan Army Medical Center, Tacoma, Washington, USA (2003),
“Major Incident Medical Management and Support (MIMMS) Course”,
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DEAN OF THE FACULTY AND HIS DEPUTIES
Oberammergau, Germany (2009), “Advanced Trauma Life Support Course
for Doctors”, Hradec Králové (2013).
Colonel Jiří Páral is the Czech Armed Forces’ chief surgeon. He has
devoted most of his career to abdominal surgery, colorectal surgery
and upper gastrointestinal tract surgery. The background of multinational
mission deployments gives him ample experience in organ traumatology,
emergency and urgent care medicine. He is the author of two and co-author
of three scientific monographs, of a number of lectures presented in and
beyond the Czech Republic and of articles published in national and
international reviewed journals.
DEAN OF THE FACULTY
AND HIS DEPUTIES
CHLÍBEK Roman
e-mail: [email protected]
(till 14 October 2013)
Dean:
PÁRAL Jiří
(since 15 October 2013)
Vice-Dean for Studies: PROCHÁZKA Miroslav e-mail:
[email protected]
Vice-Dean
BOŠTÍK Pavel
for Research:
(since 01 January 2013)
Vice-Dean for External BLANAŘ Roman
Relations and
Development:
Head of Logistics:
TOMÁŠIK Marian
Dean:
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SCIENTIFIC COUNCIL, ACADEMIC SENATE
MEMBERS OF THE SCIENTIFIC COUNCIL
ANZENBACHER Pavel
ČERVINKA Miroslav
FILIP Stanislav
HERNYCHOVÁ Lenka
CHLÍBEK Roman
JURENKA Božetěch
(since 01 November 2013)
KLEIN Leo
LÁZNÍČEK Milan
PÁRAL Jiří (since 01 November 2013)
PRYMULA Roman
SLABÝ Antonín
ŠPLIŇO Miroslav
VALACH Ivan (till 30 October 2013)
BOŠTÍK Pavel
FERKO Alexander
(till 30 October 2013)
FUSEK Josef
HLÚBIK Pavol
JEBAVÝ Ladislav
KASSA Jiří
KUČA Kamil
ÖSTERREICHER Jan
PELLANT Arnošt
RYŠKA Aleš (till 30 October 2013)
STULÍK Jiří
ŠUBRT Zdeněk
(since 01 November 2013)
VÁVROVÁ Jiřina
MEMBERS OF THE ACADEMIC SENATE
Academic members
HERNYCHOVÁ Lenka (till 22 October 2013)
HORÁČEK Jan (since 23 October 2013)
HRSTKA Zdeněk
JAKL Martin (since 23 October 2013)
JUN Daniel (Head of the senate)
KUBELKOVÁ Klára (since 23 October 2013)
LOCHMAN Petr (since 23 October 2013)
MUSÍLEK Kamil (till 22 October 2013)
PÁRAL Jiří (till 22 October 2013)
PAVLÍK Vladimír (since 23 October 2013)
PSUTKA Jan (till 22 October 2013)
SMETANA Jan (till 22 October 2013)
ŠINKOROVÁ Zuzana (Vice-chairman)
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ACADEMIC SENATE, EDUCATION COMMISSION
ZÁRYBNICKÁ Lenka (since 23 October 2013)
ŽĎÁROVÁ KARASOVÁ Jana (Head of the senate, till 22 October 2013)
Student members
HEDÁNEK Daniel (till 22 October 2013)
JANOUŠKOVÁ Karla (till 22 October 2013)
KOTEK Jiří (since 23 October 2013)
KUČERA Tomáš (Vice-chairman, since 23 October 2013)
MÜLLER Petr (since 23 October 2013)
POLCAROVÁ Petra (since 23 October 2013)
PUDÍK Peter (since 23 October 2013)
ŘEZÁČ David (Vice-chairman, till 22 October 2013)
SKOŘEPA Pavel (till 22 October 2013)
STODOLA Petr (since 23 October 2013)
MEMBERS OF THE EDUCATION COMMISSION
BRNDIAR Miroslav
KONŠTACKÝ Stanislav
POHANKA Miroslav
PROCHÁZKA Miroslav
ROHLENA Milan
STŘÍTECKÁ Hana
ŠMÍRA Pavel
ŠUBRT Zdeněk
VOPLATKOVÁ Zdeňka
HRSTKA Zdeněk
MÍŠKOVÁ Zdena
POTÁČ Michal
PUDÍK Peter (Head of the education commission)
SMETANA Jan
STULÍK Jiří
ŠTĚTINA Rudolf
TICHÝ Aleš
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EDITORIAL COMMISSION
MEMBERS OF THE EDITORIAL COMMISSION
HRSTKA Zdeněk
POHANKA Miroslav
PROCHÁZKA Miroslav
(Head of the editorial commission)
ROHLENA Milan
STŘÍTECKÁ Hana
ŠMÍRA Pavel
ŠUBRT Zdeněk
VOPLATKOVÁ Zdeňka
BRNDIAR Miroslav
KONŠTACKÝ Stanislav
POTÁČ Michal
PUDÍK Peter
SMETANA Jan
STULÍK Jiří
ŠTĚTINA Rudolf
TICHÝ Aleš
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CENTRE OF ADVANCED STUDIES
Educational and Research Staff
BOŠTÍK Pavel (Head of the Institute)
JOŠT Petr
JUN Daniel (Head of the Group)
KAISLEROVÁ Lenka
KUBELKOVÁ Klára
KUČA Kamil
PEJCHAL Jaroslav (Head of the Group)
POHANKA Miroslav (Head of the Group)
SHESHKO Valeria
SCHMIDT Monika (since 01 July 2013)
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
Technicians
HERMAN David
HRABINOVÁ Martina
TÓTHOVÁ Iveta
ŽÁKOVÁ Jitka
[email protected]
[email protected]
[email protected]
[email protected]
Administrative, Secretarial and Other Staff
ANTONINOVÁ Jana (since 01 May 2013)
MAZUROVÁ Iva
Postgraduate Students
BABKOVÁ Kateřina (since 01 October 2013)
DRTINOVÁ Lucie
GILAROVÁ Zuzana
KAISLEROVÁ Lenka (till 01 October 2013)
KRAČMAROVÁ Alžběta
KŘENKOVÁ Zuzana
VÁŇOVÁ Nela (since 01 October 2013)
[email protected]
[email protected]
[email protected]
Centre of Advanced Studies is an integral part of Faculty of Military
Health Sciences of University of Defence, Czech Republic. The main task
of the Centre is the transfer, utilization, and dissemination of advanced
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technologies for biomedical defence research and research related
to the prophylaxis and pathogenesis of dangerous infectious diseases.
Research projects performed at the Centre are funded by both the Ministry
of Defence and various national and international grant agencies. The
biological labs of BSL2 and BSL3 category and chemical lab for the analyses
of highly toxic chemicals are available for research on both highly pathogenic
microorganisms and highly toxic substances. The team of the Centre utilizes
and develops up-to date technologies in all three areas of interest –
Biological, Chemical and Radiological. Among them are technologies
for histochemistry,
immunohistochemistry,
laser
microdissection,
fluorescence microscopy, proteomic technologies including isolation and
proteomic analysis of total membrane proteins and lipid-raft associated
proteins, genomic technologies oriented to qRT-PCR applications, gene
reporter assays, genomic manipulation of bacteria, virus identification and
typization assays, technologies for the qualitative and quantitative analyses
of antidotes and chemical warfare agents in biological samples using
different HPLC techniques, methods for determination of oxidative stress,
construction of biosensors, in vitro testing of quaternary and non-quaternary
inhibitors of enzyme acetyl cholinesterase, cytotoxicity evaluation of new
compunds, and finally microbiological technologies needed for screening
of functional properties of bacterial mutants (proliferation assays and
protective tests).
CBRN programmes in 2012 follow the long-lasting research strategy
of the Centre. B-agent programme involves several topics aimed
at management of biological crises, modelling & risk assessment, (immuno)
prophylaxis of infections, immunopathogenesis of viral diseases, such as HIV
and herpetic viruses, and certain biological agents (Francisella tularensis).
In addition, new projects focus on the development of prophylactic means
utilizing nanotechnologies in the areas of virus induced diseases
in immunosuppressed organisms (e.g. by radiation). C-agent programme is
focused on development of new prophylactic and therapeutic antidotes and
toxic agent scavengers utilizing the methodology of 3D in silico modelling
and simulation of bio-molecular three- and fourdimensional structures and
inter-molecular
interactions.
RN-agent
programme
encompassing
the problems of molecular markers of ionizing radiation injury is divided into
biodosimetry and diagnosis and therapy of ionizing irradiation syndromes.
New international contacts have been established with several European
and US military and civilian research institutions. Moreover, the broad-based
collaboration under the umbrella of European Defence Agency started to be
the indispensable tool for reinforcement of scientific collaboration inside
the European Union. Collaboration with partners is supported by two-side
or multilateral projects. During short time of its existence the Centre
of Advanced Studies thus achieves all attributes of fully consolidated
scientific centre collaborating with substantial number of prominent European
scientific institutions.
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RESEARCH PROJECTS
Correlation of expression of KIR alleles in NK cells in GALT
and disease progression in SIV non-human primate model of AIDS
Boštík, P., Boštíková, V.
Supported by the Ministry of Education, Youth and Sports, 2011–2014
(Project No.: LH11019)
The HIV infection in humans leads to AIDS, a deadly disease, which
targets predominantly cells of the immune system. It has recently become
clear that also the innate immune cells, such as NK cells play an important
role in the response to the virus, especially in the acute phase, which
dictates the subsequent course of the disease. The activation and inhibition
processes that are in part tied to an expression of certain variants of the
Killer-Ig-like receptors (KIRs) on these cells were shown to be associated
with distinct outcomes of HIV disease. The aim of this project is to
characterize the expression of KIR variants on NK cells in the gut associated
lymphoid tissue in SIV infected rhesus macaques (RM), the only available
model of human AIDS, and their correlation to the course of AIDS in RM.
In addition, monoclonal antibodies against these variants, will be developed
as new reagents. These data will further our knowledge of AIDS
pathogenesis and may help in the subsequent vaccine design.
Determination of apoptosis in the bioptic samples taken from the colon
Kohoutová, D., Pejchal, J., Šmajs, D.
Supported by the Internal Grant Agency of the Czech Republic Health
Service, 2012–2015 (Project No.: NT13413)
Apoptosis of colonic epithelial cells is of a very low degree in healthy
humans. Factors, which influence (increase) apoptosis, have not been
satisfactory explained yet. Not only primary disease itself (inflammatory
bowel disease, adenoma, carcinoma), but also luminal pH and pH of the
mucosa, different expression of blood group antigens, alteration of mucosal
prostaglandines and S100 proteins, microbial population, nutrition etc. may
play a role in apoptosis. The project will use advanced endoscopic methods,
most modern possibilities of apoptosis determination in the bioptic samples
(taken during colonoscopy), direct measurement of mucosal pH and
bacteriocinogenotypization.
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Improvement of vaccination efficacy by cholinergic anti-inflammatory
pathway
Pohanka, M., Hrabinová, M., Pavlík, M., Boštík, P., Kuča, K.
Cholinergic antiinflammatory pathway (CAP) is an important tool
of regulation of innate immune responses mediated by the parasympathetic
nervous system. The project is aimed at evaluating the performance of drugs
affecting CAP as vaccine adjuvans. The primary hypothesis is that
a suppression of CAP can potentiate the vaccination efficacy. Compound HI6 inhibiting blood acetylcholinesterase will be tested for control purposes
in comparison to drugs triggering CAP. The project will cover the following
aspects :in vitro tests of drug effects, examination of effects of tested drugs
on immune system alone and co-application of tested drugs
with commercially available vaccine in comparison to the effect
of the vaccine alone in-vivo in small laboratory animals. Basic
immunochemical parameters such as immunoglobulin isotypes M and G,
interleukins 2, 4 and 6 and selected biochemical parameters will be
assessed. The expected results of project will be improvement of vaccines
efficacy and better characterization of CAP as target of the selected drugs.
Neurobehavioral evaluation of potential Alzhemier`s disease drugs
Kassa, J., Misík, J., Kuča, K., Musílek, K., Žďárová Karasová, J.
Supported by the Czech Republic Grant Agency, 2012–2015 (Project No.:
GAP303/12/0611)
The permanent increasing incidence of Alzheimer`s disease represents
a worldwide problem that can be partly solved by introducing more effective
drugs. The aim of the stuidy is to characterize the effects of newly developed
acetylcholinesterase inhibitors with better pharmacodynamic features derived
from the model drug 7-methoxytacrine on nervous functions and especially
cognitive functions. The effects of drugs will be evaluated in laboratory rats
with the deficiency of cognitive functions induced by administration of 3chinuclidinylbenzilate. The effects of newly developed drugs will be
evaluated by functional observational battery and the potency to eliminate
or reduce the deficiency of cognitive functions by special neurobehavioral
methods oriented on memory and learning. The effects of new drugs
on nervous functions and their potency to eliminate the deficiency
of cognitive functions will be compared to the effects of a model drug and
standard therapeutics (tacrine, donepezil, rivastigmine). Proposed study can
contribute to the increase of the effectiveness of the treatment of Alzheimer`s
disease.
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New technologies for identification and typing of biological agents
Kročová, Z., Boštík, P., Hanovcová, I., Jun, D., Macela, A.
Supported by the Czech Republic Ministry of Internal Affairs, 2012–2015
(Project No.: VF20122015024)
The aim of the project is to develop the methodological procedures
for the isolation of bacterial and viral nucleic acids and protein and no-protein
toxins from natural matrices, and the procedures for their identification and
typing. In the case of bacteria and viruses are designed following the
methodological procedures and specific technological and laboratory units:
the acquisition and cultivation of biological agents, isolation of genome and
plasmid DNA, or RNA in the case of a virus, the methodology and
procedures for the preparation of samples of bacterial and viral nucleic acids
from complex matrices, design of qPCR primers, probes and the reaction
conditions and testing and validation of the proposed methods and
procedures for the identification of biological agents. For the detection of low
molecular weight toxins will be used high performance liquid chromatography
coupled with tandem mass spectrometry and for detection and identification
of protein toxins will be used mass spectrometric method SRM (Selected
reaction monitoring).
Novel inhibitors of acetylcholinesterase derived from 7-MEOTA –
potential Alzheimer´s disease drugs
Kuča, K., Řípová, D.
GAP303/11/1907)
Worldwide incidence of AD was evaluated to 35 million of people in 2009.
The amount of AD patients in 2050 was estimated to 110 million. The most
important factor influencing the increasing amount of AD patients is the age
of population (particularly European is rapidly ageing). Thus, the AD is
becoming a priority of public health care and there is demand for novel drugs
suitable for its treatment.The main aim of this project consist in synthesis and
evaluation of novel acetylcholinesterase (AChE) inhibitors derived from 7MEOTA as potential AD drugs. Synthesized AChE inhibitors will be tested
using experimental batery consisting of molecular modelling, biochemical
evaluation of AChE inhibitors, antioxidant evaluation of novel drugs,
Interactions with muscarinic/nicotinic receptors and choline transporters,
in vitro prediction of blood-brain barrier penetration, determination of acute
toxicity of selected AChE inhibitors, evaluation of plasmatic levels after
experimental administration, evaluation of novel AChE inhibitors in CNS.
Based on the appropriately-managed testing system of novel AChE
inhibitors, suaitable candidate will be selected and recommended for further
preclinical trial.
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Preparation and biological evaluation of new therapeutics against
to pesticides
Kuča, K., Žďárová Karasová, J., Pohanka, M., Jun, D.
The main aim of this project is to search for new and convenient
therapeutics that will be more effective in therapy of pesticide poisoning
(pesticides
are
commonly
used
organophosphate
inhibitors
of cholinesterases). New structures will be determined by using highly
sophistic methodology: molecular design. Predicted structures and their
analogues will be synthesized. Their therapeutic potency will be tested
in in vitro studies. The acetylcholinesterase reactivators with the highest
reactivation potency will be chosen into in vivo tests. During this
development process other important data such as LD50 of newly
synthesized therapeutics, biochemical studies and pharmacokinetics studies
(distribution of newly prepared therapeutics and their ability to penetrate
through the blood-brain barrier into central nervous system) will be also
replenished. If some effective candidates will be found, subsequent
cooperation with foreign institutes is presumed.
The role of virus associated cellular proteins in T-lymphocyte
dysfunction
Boštík, P., Řehulka, P., Pejchal, J., Boštíková, V., Kročová, Z.
GAP304/10/1161)
Herpetic viruses, such as VZV, and lentiviruses, such as HIV or SIV, are
enveloped viruses, which infect CD4 T cells and cause transient (VZV)
or progressive (SIV) dysregulation of T cell function. This effect is mainly
indirect, as the fraction of infected cells is small, but the dysregulatory effect
is observed in much larger cell population. These viruses incorporate hostderived proteins into their envelopes during the process of virus maturation
and these proteins can either retain their function or engage their receptors
and subsequently initiate intracellular signaling. This can be mediated by AktGSK3 pathway and PGE metabolism, leading to T cell dysfunction and
apoptosis. This proposal utilizes state-of the art proteomic approach to
Identification of host cell proteins incorporated into the SIV and VZV virions.
The role of these host cell proteins will be subsequently investigated in their
effects on CD4 T cell signaling cascades and can therefore lead
to the elucidation of mechanisms involved in CD4 T cell dysfunction and
death in such diseases as chickenpox and AIDS.
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Whole varicella-zoster virus (VZV) genome sequencing of individual
wild type and vaccine strains using GS Junior Benchtop System
Boštíková, V., Smetana, J., Kaislerová, L., Boštík, P.
Supported by the Roche co., 2010–2014 (Project No.: VZV)
Varicella-zoster virus (VZV) is a highly infectious herpesvirus that affects
up of the 90 % of human population. VZV causes chickenpox (varicella)
predominantly in childhood and shingles (herpes zoster) in middle to old age
people. While VZV usually causes relatively mild disease in healthy
individuals, VZV still causes significant morbidity in children and adults. VZV
causes life-threatening disease in immunocompromised individuals such
as patients who are elderly or have HIV disease . Herpes zoster affects
many elderly individuals and a major complication is prolonged severe pain
or post-herpetic neuralgia (PHN), both severely debilitating.
The epidemiology of VZV varies geographically. We use a novel strategy
for VZV genotyping based on sequencing using DNA amplified from clinical
samples. Using this method, more than 400 strains isolated in Czech
Republic sorted into discrete geographically distributed genotypes. Recently
we continue work on the improvement of the method and we try to find more
genotypes in the individual groups.
The second part of study yield important data of genetic diversity of VZV
in Czech Republic, which will play an important role in further understanding
of epidemiology and evolution of the virus, and may in future serve as a tool
for genetic prediction of virus pathogenicity or resistance development.
Previous data from several laboratories, predominantly in the US and UK,
indicate a specific geographic distribution of these strains as well as their
potential propensity for recombination with other wild type (wt) or vaccine
strains. New pyrosequencing method using GS Junior Benchtop System
of whole VZV genomes further refined the phylogenetic distinctions between
SNP genotypes. The new data will bring more light to widespread
surveillance in countries in which the varicella vaccine is now in use.
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DEPARTMENT OF COMMUNICATION AND INFORMATION SYSTEMS
DEPARTMENT OF COMMUNICATION
AND INFORMATION SYSTEMS
BLAŽEK Pavel (Head of the Group)
VOPLATKOVÁ Zdeňka
ZEDNÍČEK Jiří (Head of the Department)
[email protected]
[email protected]
[email protected]
Technicians
KOMÁREK Vladimír
RYDRYCH Jiří
[email protected]
[email protected]
HRDLIČKOVÁ Lenka
VÍCHOVÁ Eva
ZIKOVÁ Jitka
[email protected]
[email protected]
[email protected]
The Department of communication and information systems provides
the top quality information service to ensure efficient scientific, research and
teaching activities for teaching and research staff as well as under- and
postgraduate students of our faculty.
The Department of communication and information systems consists
of the group of computer applications and the library of faculty.
The group of computer applications provides the operation
of the faculty network, enables access to army, specialized and public
information systems and supplies the needs of the Faculty with modern
information technologies. Main activity of the group is ensuring the access
to INTERNET and to specialized information systems. Management of data
network, central management of software, servicing as well as specialized
support of users is also provided.
Part of this group are also graphic services that create graphic
documents and posters for presentations, make arrangements and changes
of drafts for printing, make digital pictures and do other associated work. It
also provides the operating and updating of the web site of the Faculty
(http://www.pmfhk.cz).
The printing-office of the Department of communication and information
systems is able to cover reprographic and printing needs of the Faculty by its
own sources in limited extent.
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DEPARTMENT OF COMMUNICATION AND INFORMATION SYSTEMS
The library provides students, research and teaching staff of the Faculty
of Military Health Sciences and members of the Czech Army Medical Service
with scientific and information services. The main information services are
provided by the library with 85 000 library units concerning medicine as well
as associated branches. Information sources in the field of military medicine,
emergency medicine and disaster medicine are specificity of this library. The
library enables access to various information databases (WoK,
ScienceDirect, SCOPUS, SpringerLink, BiblioMedica, etc.) and provides
systematic help when being used.
The group participates in teaching activities in the doctoral study
programmes and scientific education (Ph.D.) by giving lectures in Basics
of Informatics focused on retrievals, processing and publication of scientific
information. It also takes part in undergraduate programme in military rescue
workers.
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DEPARTMENT OF EPIDEMIOLOGY
BOŠTÍKOVÁ Vanda
HANOVCOVÁ Irena (Head of the Group)
CHLÍBEK Roman (Head of the Department)
MAREK Jan
PRYMULA Roman
SMETANA Jan (Head of the Group)
ŠOŠOVIČKOVÁ Renata (since 01 September 2013)
ŠPLIŇO Miroslav
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
Technicians
BERNARDOVÁ Marta
KOŠŤÁLOVÁ Lenka
MALÍKOVÁ Martina
ŘÍHOVÁ Iva
SOLÁROVÁ Alena
VOŽENÍLKOVÁ Kristýna
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
LEGERSKÁ Kateřina
[email protected]
ANTAL Zdeněk
BAREKOVÁ Lucie
BLECHOVÁ Zuzana (till 12 June 2013)
COUFALOVÁ Monika
ČEČETKOVÁ Beáta (till 01 October 2013)
DÍTĚ Petr
DYRHONOVÁ Markéta (since 01 October 2013)
FAJFR Miroslav
HEDLOVÁ Dana
HOBZOVÁ Lenka (since 01 October 2013)
MACHAČ Jan
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OLEFIRENKO Kateřina (since 01 October 2013)
PEK Miroslav (till 21 August 2013)
SLEHA Radek
VALENTA Zbyněk (till 01 October 2013)
ZELENÁ Hana (since 01 September 2013)
The Department of Epidemiology as the basic educational and research
component of the Faculty of Military Health Sciences (FMHS) is divided into
two groups: the epidemiology group and the microbiology, disinfection,
disinsection and rodent control group.
The Department of Epidemiology has fulfilled the following main tasks:
It has provided undergraduate education at the FMHS and at the civilian
Medical Faculty of Charles University in Hradec Králové, as well
as postgraduate training and postgraduate doctoral studies. The teaching
activities have been particularly aimed at general and special epidemiology
with respect to the topical situation in the Czech Army and in the Czech
Republic. The topics of ”Emerging and Reemerging, Infectious Diseases”,
“Travel Medicine” and “Dangerous Pathogens” have also been emphasized.
Doctoral study programmes (Ph.D. – epidemiology and medical
microbiology) are certified by the Czech Governmental Commission. Since
1997, more than 30 students have finished their Ph.D. studies.
The Department of Epidemiology plays an important role in education,
training and consultancy related to biological threats/weapons and preventive
medicine.
The members of the department participate in training and education
of medical and other personnel dispatched in military peacekeeping and
humanitarian missions abroad. The aim is to inform them about any health
risks during staying abroad, especially about prevention of infectious
diseases, possibilities of vaccination or chemoprophylaxis. They also provide
both consultancy service prior to the departure abroad and a practical
realization of the respective measures. The Department of Epidemiology
provides an epidemiological service for the Field Hospitals of the Czech
Army.
Research activities have concerned clinical evaluation of the new
vaccines like pneumoccocal vaccines, herpes zoster vaccines, Human
Papiloma Virus vaccines, rotavirus vaccines, new adjuvanted vaccines
against viral hepatitis B, Lyme disease vaccines, combined hepatitis B and
typhoid fever vaccines, flu vaccines, meningoccoccal B vaccines or new
vaccination schedules.
Members of the department are members of different Czech journals
editorial boards (e. g. “Epidemiologie, mikrobiologie a imunologie” – Prof.
Splino, Military Medical Science Letters – Prof. Chlibek), and they work
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as reviewers of international journals (Vaccine, Lancet Infectious Disease).
Some of them work in a number of committees and boards: Vice-chairman
of Czech Immunization Committee of the Ministry of Health (Prof. Chlibek),
or European Centre for Disease Control and Prevention (Prof. Prymula, Prof.
Chlibek), or Central European Vaccination Awareness Group-CEVAG (Prof.
Prymula, Prof. Chlibek). Prof. Splino and Ass. Prof. Bostikova had oportunity
to serve as members for Advisory Board for the Investigation and Control
of Influenuza and Other Epidemic Disease and Section for Control
and Development of Diagnostics Laboratory Methods of CDC.
Members of the department are also members of NATO working groups
and advisory committees for biological threats and weapons (BIOMEDAC –
Biological Medical Advisory Committee – Prof. Chlibek) and NATOResearch&Technology Organisation (Prof. Chlibek).
Disinfection, disinsection and rodent control are very important parts
of the medical practice in the Czech Army. This department is the only one
of its kind in the Czech Army for the assessment of the antimicrobial efficacy
of disinfectants.
The researchers of the microbiology group have also solved questions
concerning the prevention of endogenous and exogenous infections
in immunocompromised patients.
RESEARCH PROJECTS
A phase III, randomized, observer-blind, placebo controlled,
multicentre, clinical vaccination trial to assess the prophylactic
efficacy, safety and immunogenicity of GSK Biologicals’ herpes zoster
gE/AS01B vaccine when administered intramuscularly on a 0, 2-month
schedule in adults aged 70 years and older
Chlíbek, R., Kalíšková, E., Smetana, J., Ditě, P., Gál, P., Vokurková, D.
Supported by the GlaxoSmithKline Biologicals co., 2010–2015 (Project No.:
113077 (ZOSTER-022))
A phase III, randomized, observer-blind, placebo controlled, multicentre,
clinical vaccination trial to assess the prophylactic efficacy, safety
and immunogenicity of GSK Biologicals’ herpes zoster gE/AS01B vaccine
when administered intramuscularly on a 0, 2-month schedule in adults aged
70 years and older. Chlíbek, R., Smetana, J., Gál, P., Dítě, P., Kalíšková, E.,
Vokurková, D. Supported by the GSK, 2010–2015 (Project No.: 113077
(ZOSTER-022) Study ZOSTER-022 will provide data on the vaccine efficacy
in prevention of herpes zoster (HZ) and Postherpetic neuralgia (PHN)
compared to placebo in adults ≥ 70 YOA. The ZOSTER-022 study will enrol
subjects in the age ranges 70-79 YOA and ≥ 80 YOA in a 3:1 ratio.
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A phase III, randomized, observer-blind, placebocontrolled, multicentre,
clinical vaccination trial to assess the prophylactic efficacy, safety, and
immunogenicity of GSK Biologicals´ herpes zoster gE/AS01B vaccine
when administered intramuscularly on a 0, 2-month schedule in adults
aged 50 years and older
Chlíbek, R., Kalíšková, E., Smetana, J., Dítě, P., Gál, P., Vokurková, D.
110390 (ZOSTER-006))
Study ZOSTER-006 will provide pivotal data on the overall efficacy
in prevention of herpes zoster (HZ) in subjects ≥ 50 YOA. The primary
endpoint of this study will be overall HZ vaccine efficacy (VE) across all age
cohorts. To this end, ZOSTER-006 will evaluate VE of the gE/AS01B vaccine
compared to placebo in reducing the risk of developing HZ in subjects ≥ 50
YOA. This study will enrol subjects in the age ranges 50-59 YOA, 60-69
YOA, 70-79 YOA and ≥ 80 YOA.
A phase 3, open label, multi-center, extension study to assess antibody
persistence and response to a third dose of Novartis meningococcal B
recombinant vaccine in 4-year-old children who previously participated
in study V72P12E1
Prymula, R., Chlíbek, R., Jarolímek, J., Karlová, V., Říhová, J., Hrunka, S.,
Novák, L.
Supported by the Novartis, 2012–2013 (Project No.: V72P12E2, EUDRACT
No 2011-004931-30)
The main aim of the study is to explore the bactericidal antinody
persistence in 4-year-old children after a fourth dose boost of rMenB+OMV
NZ given at 12, 18, or 24 months of age or after a two-dose catch-up
schedule of rMenB+OMV NZ administered at either 12 and 14, 18 and 20,
or 24 and 26 months of age in study V72P12E1. Safety objectives are
to assess the safety and tolerability of a third/fifth dose boost of vaccine or
two catch-up doses administered 2 months apart to naïve 4-year-old
children. Immunogenicity objectives are to explore antibody persistence after
a fourth dose boost of the vaccine administered at either 12, 18, or 24
months of age in toddlers who previously received a three-dose primary
series of rMenB+OMV NZ as infants (at 2, 3, 4 or 2, 4, 6 months of age).
An open, phase II long term extension study to evaluate the immune
responses to and safety of GSK Biologicals’ candidate herpes zoster
vaccine (gE/AS01B) at Months 48, 60 and 72 post-vaccination in healthy
subjects aged 60 years of age and older
Chlíbek, R., Smetana, J., Kalíšková, E.
114825, Zoster-024)
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The purpose of this long-term follow-up study (ZOSTER-024) is
to evaluate the immune responses of subjects who previously participated
in study ZOSTER-003. Long term safety of the study vaccine administered
in ZOSTER-003 will also be evaluated.
Correlation of expression of KIR alleles in NK cells in GALT and
disease progression in SIV non-human primate model of AIDS
Boštík, P., Boštíková, V.
The HIV infection in humans leads to AIDS, a deadly disease, which
targets predominantly cells of the immune system. It has recently become
clear that also the innate immune cells, such as NK cells play an important
role in the response to the virus, especially in the acute phase, which
dictates the subsequent course of the disease. The activation and inhibition
processes that are in part tied to an expression of certain variants
of the Killer-Ig-like receptors (KIRs) on these cells were shown to be
associated with distinct outcomes of HIV disease. The aim of this project is to
characterize the expression of KIR variants on NK cells in the gut associated
lymphoid tissue in SIV infected rhesus macaques (RM), the only available
model of human AIDS, and their correlation to the course of AIDS in RM.
In addition, monoclonal antibodies against these variants, will be developed
as new reagents. These data will further our knowledge of AIDS
pathogenesis and may help in the subsequent vaccine design.
Epidemiological observational prospective cohort study to evaluate the
sero-prevalence of Bordetella pertussis in adults in the Czech Republic
Chlíbek, R., Smetana, J.
115790 EPI-Pertussis)
Pertussis in adolescents and adults is common, endemic and epidemic
and its incidence is reportedly increasing. Adolescents and adults are
the groups most commonly infected with pertussis and are the major source
of contagion to infants and young children. This population based study
could give an evidence to define new strategies to prevent pertussis in adults
and to support the need to include aP booster in adults. The main aim of the
study is to determine sero-prevalence of Bordetella pertussis infections
in adults in the Czech Republic. The secondary objectives are to determine
the age specific sero-prevalence of high antibody titres to Bordetella
pertussis in individual age cohorts: 18–29 years of age, 30–44 years
of age,45–59 years of age and 60+ , to describe the differences in age, sex,
history of a contact with pertussis, history of long –lasting cough, history
of medication and hospitalization due to respiratory infections in previous 12
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months, history of pertussis vaccination status and to identify the subjects
with asymptomatic pertussis in previous 12 months.
(Project No.: VF20122015024)
toxins from natural matrices, and the procedures for their identification and
typing. In the case of bacteria and viruses are designed following
the methodological procedures and specific technological and laboratory
units: the acquisition and cultivation of biological agents, isolation of genome
and plasmid DNA, or RNA in the case of a virus, the methodology and
procedures for the preparation of samples of bacterial and viral nucleic acids
from complex matrices, design of qPCR primers, probes and the reaction
conditions and testing and validation of the proposed methods and
procedures for the identification of biological agents. For the detection of low
molecular weight toxins will be used high performance liquid chromatography
coupled with tandem mass spectrometry and for detection and identification
of protein toxins will be used mass spectrometric method SRM (Selected
reaction monitoring).
dysfunction
GAP304/10/1161)
and subsequently initiate intracellular signaling. This can be mediated by AktGSK3 pathway and PGE metabolism, leading to T cell dysfunction and
apoptosis. This proposal utilizes state-of the art proteomic approach to
to the elucidation of mechanisms involved in CD4 T cell dysfunction and
death in such diseases as chickenpox and AIDS.
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Whole varicella-zoster virus (VZV) genome sequencing of individual
Boštíková, V., Smetana, J., Kaislerová, L., Boštík, P.
Supported by the Roche co., 2010–2014 (Project No.: VZV)
Varicella-zoster virus (VZV) is a highly infectious herpesvirus that affects
up of the 90 % of human population. VZV causes chickenpox (varicella)
predominantly in childhood and shingles (herpes zoster) in middle to old age
people. While VZV usually causes relatively mild disease in healthy
individuals, VZV still causes significant morbidity in children and adults. VZV
causes life-threatening disease in immunocompromised individuals such as
patients who are elderly or have HIV disease . Herpes zoster affects many
elderly individuals and a major complication is prolonged severe pain or postherpetic neuralgia (PHN), both severely debilitating.
The epidemiology of VZV varies geographically. We use a novel strategy
for VZV genotyping based on sequencing using DNA amplified from clinical
samples. Using this method, more than 400 strains isolated in Czech
Republic sorted into discrete geographically distributed genotypes. Recently
we continue work on the improvement of the method and we try to find more
genotypes in the individual groups.
The second part of study yield important data of genetic diversity of VZV
in Czech Republic, which will play an important role in further understanding
of epidemiology and evolution of the virus, and may in future serve as a tool
for genetic prediction of virus pathogenicity or resistance development.
Previous data from several laboratories, predominantly in the US and UK,
indicate a specific geographic distribution of these strains as well as their
potential propensity for recombination with other wild type (wt) or vaccine
strains. New pyrosequencing method using GS Junior Benchtop System
of whole VZV genomes further refined the phylogenetic distinctions between
SNP genotypes. The new data will bring more light to widespread
surveillance in countries in which the varicella vaccine is now in use.
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DEPARTMENT OF FIELD INTERNAL MEDICINE
DEPARTMENT OF FIELD INTERNAL
MEDICINE
BRNDIAR Miroslav
HORÁČEK Jan (Head of the Group)
JAKL Martin
JEBAVÝ Ladislav (Head of the Department)
KAČEROVSKÝ Jaroslav (Prof. Emerit.)
KUPSA Tomáš
TICHÝ Miloš (Prof. Emerit.)
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
MACHAČOVÁ Iva
[email protected]
BROULÍKOVÁ Karolina
(since 01 October 2013)
HAJŠL Martin (since 01 October 2013)
JARKOVSKÝ Patrik (since 01 October 2013)
KUPSA Tomáš
PRACHAŘOVÁ Šárka
RUČKA David
SEDLOŇ Pavel
VOŠKA Michal (since 01 October 2013)
[email protected]
[email protected]
[email protected]
The Department of Field Internal Medicine focuses systematically
on the specialized postgraduate level of medical studies in the branch of field
internal medicine. This discipline deals with specific military problems,
in particular with the problem of saving the lives of patients suffering from
serious and life-threatening conditions of non-surgical character. Such
injuries generally occur during mass disasters both in wartime and
in peacetime.
In the Department of Field Internal Medicine the development of military
internal medicine follows three basic directions or areas: therapy and
prevention, pedagogical and educational methods, and scientific research:
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Work in therapy and prevention is essential for military internists,
because it enables us to acquire and develop good professional
aptitude and experience in care for the seriously ill.
The pedagogical and educational aspect of our work follows
from our therapeutic/preventive activities. The Department
coordinates the Branch Council of Clinical Medical Fields and
the Branch Council of Postgraduate Study for Doctorates
in Accredited Disciplines of Field Internal Medicine (equivalent
of Ph.D.).
Scientific research is the Department´s third main area
of activity. Essentially, it extrapolates the results of applied
clinical research into specific military conditions and into medical
care under field conditions.
In 2013 the research in the Department continued in the five basic fields:
Haematology – growth of stem cells – preparation for bone
marrow transplantation
Biochemical and electrophysiologic investigation and monitoring
of acute coronary syndromes
Cardiotoxicity of antitumorous therapy
Diagnosis and therapy of hypercoagulative states – the
monitoring of anticoagulant therapy
Global quality of life in patients who have undergone the
hematopoietic stem cell transplantation
Cooperation in the clinical research:
1. Haematopoietic stem cell transplantation. A role of cytokines
in transplantation. Transplant-related complications and supportive care
has continued.
2. A study in the application of enteral and parenteral nutrition in intensive
metabolic care has continued.
3. The study of supraventricular tachycardias – electrophysiologic
investigation and therapy including radiofrequency ablation has
continued.
4. Participation (co-investigators) on international study IRIS – Immediate
Risk-stratification Improves Survival, primary prevention of sudden
cardiac death.
5. Cardiotoxicity of antitumorous therapy – the research project has
continued.
6. Projects have been carried out in the field of determination and analysis
of monoclonal immunoglobulins in the urine of patients with multiple
myeloma.
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7.
8.
9.
10.
11.
12.
13.
14.
New biochemical cardiac markers (cardiac troponin T, high sensitivity
CRP, brain natriuretic peptide) – clinical and laboratory evaluation has
continued.
Analysis of transplantation activities, indications and results in the Czech
Republic – National Stem Cell Transplantation Registry.
GvHD prophylaxis with ATG-Fresenius S in allogeneic stem cell
transplantation from matched unrelated donors: a randomised phase III
multicenter trial comparing a standard GvHD prophylaxis with
cyclosporine A and methotrexate with additional pretransplant ATGFresenius S. Project-No. (Fresenius): AP-AS-21-DE, Project-No. (ZKS):
S020801 Medizinische Klinik I, Universitätsklinikum Freiburg.
Research project: MZO 00179906 (Czech Ministry of Health),
Bioindicators in Hematology and Internal Medicine.
A double-blind, randomized, placebo-controlled study of two different
schedules of Palifermin (pre- and post chemotherapy and prechemotherapy only) for reduction in severity of oral mucositis in subjects
with multiple myeloma (MM) receiving high dose Melphalan followed by
autologous peripheral blood stem cell transplantation (PBSCT): AMGEN,
Protocol no. 20050219.
A long-term organization development plan 1011.
Double blind, randomised, placebo-controlled multicentre phase III
clinical study followed by open-label phase on the efficacy and
tolerability of budesonide 3 mg effervescent tablet in patiens
with resistant oral chronic GvHD.
A phase III, double-blind, randomized, placebo-controlled, multicenter
clinical trial to study the safety, tolerability, efficacy, and immunogenicity
of V212/heat-treated varicella-zoster virus (VZV) vaccine in recipients of
autologous hematopoietic cell transplants (HCTs).
RESEARCH PROJECTS
Quality of life measurement and its influence to overall survival
in hematopoietic stem cell transplantation in CZ
Trněný, M., Novák, J., Válková, V., Jebavý, L., Sedláček, P.
The aim of our project is to document quality of life in transplanted
patients using standardised QOL questionnaires. Based on this monitoring,
we would like to propose a supportive psychological and social program
for individual institutions so that the monitoring of QOL will become
an integral part of standard medical practice.
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DEPARTMENT OF FIELD SURGERY
ČÁP Robert (Head of the Group)
DOBEŠ Daniel (till 31 July 2013)
KLEIN Leo (Head of the Group)
LOCHMAN Petr
PÁRAL Jiří (Head of the Department)
ŠIMEK Jan
ŠMEJKAL Karel
ŠUBRT Zdeněk
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
ZAHRADNÍČKOVÁ Jana
[email protected]
DOLEŽEL Radek
DUŠEK Tomáš (till 01 July 2013)
FIBÍR Aleš (till 01 July 2013)
FRANK Martin (till 17 September 2013)
KOVÁŘ Daniel
OBERREITER Martin
POHNÁN Radek
SLANINKA Igor
Structure and main tasks of the department
1. Division of General Surgery
2.
Klein Leo – Head of the Group
Division of Traumatology and Burns Treatment
Čáp Robert – Head of the Group
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Main tasks
Undergraduate education of medical students
Postgraduate training of military surgeons and other medical
specialists
Expertise and referential work for needs of the Czech Armed
Forces
Research in Military Surgery
Preparation of medical health-care personnel before foreign
missions of the Army of the Czech Republic
At present, the Department of Field Surgery consists of two groups – the
Group of General Surgery and the Group of Traumatology and Burns
Treatment. Besides working at each Division of the Department of Surgery
of the Teaching Hospital in Hradec Králové, the members of the Department
perform both, undergraduate courses in field surgery for students
of the Faculty of Military Health Science, and postgraduate training of military
physicians for their specialization exams in surgery and general medicine.
The Department also participates in teaching of the Battlefield Advanced
Trauma Life Support (BATLS) courses, disaster medicine and the first aid
courses, organized by the Faculty of Military Health Sciences for the Czech
Army members. Members of the department participate in specialised NATO
working groups according to their expertise. Moreover, they are consultans
of the Surgeon General of the Czech Armed Forces. In the last several
years, the Department has played important role in education and training
of the personnel of field hospitals operating in foreign missions (Yugoslavia,
Bosna-Herzegovina, Albania, Iraq, Afghanistan). Members of the Department
also took part in that missions. Research and publication activities are also
essential part of the Department work.
Participation in a foreign mission
F. Hošek – UNTS, Zagreb, Croatia, 1996
A. Ferko – International Hospital, SFOR, Shipovo, Bosnia and
Hercegovina, 2001
R. Čáp – International Hospital, SFOR, Shipovo, Bosnia and
Hercegovina, 2001
A. Ferko – 11th Field Hospital, ISAF, Kabul, Afghanistan, 2002
J. Páral – 11th Field Hospital, ISAF, Kabul, Afghanistan, 2002,
2011 (TSF)
M. Plodr – 11th Field Hospital, ISAF, Kabul, Afghanistan, 2002
I. Žvák – 11th Field Hospital, ISAF, Kabul, Afghanistan, 2002
D. Dobeš – British Field Hospital, Op TELIC, Shaibah, Iraq,
2004
J. Páral – British Field Hospital, Op TELIC, Shaibah, Iraq, 2004
M. Plodr – British Field Hospital, Op TELIC, Shaibah, Iraq, 2004
P. Lochman – British Field Hospital, Op TELIC, Shaibah, Iraq,
2004
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M. Plodr – 1st Contingent of the Field Hospital, ISAF, Kabul,
Afghanistan 2007
I. Žvák – 1st Contingent of the Field Hospital, ISAF, Kabul,
Afghanistan 2007
J. Páral – Czech Field Surgical Team, International Medical
Treatment Facility (Role 3) KAIA, Kabul, Afghanistan 2012
J. Šimek – Czech Field Surgical Team, International Medical
Treatment Facility (Role 3) KAIA, Kabul, Afghanistan 2012
National textbooks
Endovascular Treatment of Arterial Aneurysms (Ferko et al.)
Handbook of Surgery (Ferko et al.)
Principles of War Surgery (Klein, Ferko et al.)
X-ray Atlas of Bone Fractures (Žvák et al.)
Handbook of Bandages Technique (Páral)
Acute Mesenteric Ischemia (Páral)
International textbooks
Gastrointestinal Stromal Tumors (Páral). In Aperelho Digestivo
(Coelho), Editora Atheneau, Sao Paulo, Brasilia
RESEARCH PROJECTS
Parametric monitoring the quality of TME as a tool to reduce local
recurrences after surgery for rectal cancer
Hoch, J., Páral, J.
The aim of the project is to establish and standardize the method
of assessing the quality of surgery in the treatment of rectal cancer as a tool
to reduce the incidence of local recurrence.
The expected outcome will be improving preoperative staging, consistent
implementation and improvement procedures TME on those sites, increasing
the percentage of complete excision as a basic prerequisite for reducing
the rate of local recurrence in rectal cancer.
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Quality evaluation of multimodal treatment in patients with colorectal
liver metastatic disease: Mutlicentric study within Czech complex
oncology centres
Ryska, M., Ferko, A., Šubrt, Z.
The aim of this project is to verify the benefits of a multidisciplinary team
approach to comprehensive treatment and evaluation of results for groups
of patients defined by selected parameters, compare nationwide data
with those of selected comprehensive cancer centers, while respecting
the customized approach, to evaluate the cost / benefit and quality of life
in patients treated for colorectal cancer liver metastases.
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DEPARTMENT OF GENERAL AND EMERGENCY MEDICINE
DEPARTMENT OF GENERAL
AND EMERGENCY MEDICINE
ČMEDLOVÁ Pavlína (maternity leave, Head of the
Group)
DUŠKOVÁ Klára (maternity leave)
GRÖGER Tomáš
KONŠTACKÝ Stanislav (Head of the Group)
KRUTIŠOVÁ Pavla (since 01 January 2013)
MATOUŠEK Radovan (Head of the Department)
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
BENDOVÁ Tereza (maternity leave)
DOLEŽELOVÁ Miroslava
KRUTIŠ Jan
ŠÍSTKOVÁ Jitka
[email protected]
[email protected]
[email protected]
[email protected]
The Department of General Medicine was established at the J. E.
Purkyně Military Medical Research and Postgraduate Institute in 1983. It was
formed from the former Group of Military Medical Service Organization
in Peacetime which existed at the Department of Military Medical Service
Organization. The reason for the foundation of the Department was the need
to educate military doctors in newly established branch of General Medicine
that became the basic branch for military doctors who were in charge
of primary care in the Military Medical Service organizational structures.
Specialization in the branch of internal medicine was insufficient and did not
meet professional requirements for individual medical practice at Units and
later at Garrison Dispensaries. First Specialization Exams in this new basic
specialization branch were held in February 1985. 525 military doctors
passed the Specialization Exam in General Medicine till 31st December
2004.
Since 1997, the work at this Department has focused more on prehospital emergency care and teaching the First Aid and Emergency
Medicine. At the same time a significant modernization and a proper
subdivision of teaching premises according to the type of courses were
carried out there. Now the Department is equipped with modern teaching
models and simulators for teaching pre-hospital care, including the possibility
of interactive teaching aids. Current innovations of medical material and
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equipment are applied in teaching process. The extension of teaching
activities in this new field called for changes in table posts at the Department.
In 2001, the Healthcare Education and Training Group was established and
other workers were engaged to teach the first aid. Since 2003, regarding
the extension of teaching, the Department has had a new name –
the Department of General and Emergency Medicine.
The Department of General and Emergency Medicine is the main
department providing military-professional training in the subject called
Military Medical Service Organization in Peacetime for students
of the Master´s Study Programme in branches of General Medicine and
Military Pharmacy, and for students of the Bachelor´s Study Programme
in the branch of Military Medical Management and in various types of training
and courses. It also provides further education for military doctors,
pharmacists and other personnel of the Military Medical Service through
refresher courses and specialization courses. Until 2005, the Department
was the leading department focused on specialization training of military
doctors served in the Czech Army Medical Service. It organizes pre-graduate
courses in emergency medicine in Master´s Study Programme, but
especially post-graduate education of doctors, health care workers and
nurses. The Department of General and Emergency Medicine collaborates
with the Institute of Postgraduate Medical Education in Prague, the Chamber
of Medicine, professional medical societies and associations in postgraduate
training and specialized activities. It participates in establishing standards
for special therapeutic care.
The subject called Disaster Medicine makes students acquainted
with principles of emergency medicine and operation of individual parts
of integrated rescue system in conditions of serious accidents, natural
disasters and catastrophes. In connection with this training, the Department
provides its participants with knowledge and experience of the operation
of the Military Medical Service institutions and facilities in crisis, in combat
or other extraordinary situations. It applies the knowledge of military and
military-professional subjects into specific conditions of operation
of the Military Medical Service respecting both military principles and
requirements as well as the principles of humanity, law and especially
Geneva Conventions.
The main mission of the Department is education and training of medical
officers in casualty medical care in both combat and disaster situations.
For this purpose, the principles and procedures of emergency care in field
conditions are taught at the Department through BATLS/BARTS (Battlefield
Advanced Trauma Life Support/Battlefield Advanced Resuscitation
Techniques and Skills) courses. In the same area, the Department
participates in training of medical personnel before their departure to foreign
missions.
The next important mission od the department is education and training
of non-medical personnel in first-aid care. The most of the soldiers are
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trained in the Battlefield First-Aid Courses, some of them are trained
in consequential Combat Life Saver Courses. This course lasts 2 weeks and
offers a lot of useful knowledge and skills, e. g. control life-threatening
external hemorrhage, airway management and decompress the chest.
The graduates of this course must be able to give first aid to casualty with
very realistic looking injuries prepared by proffessional masker at the end
of the course.
The Department is a co-ordinating centre of scientific work in the branch
of Military Medical Service Organization in Peacetime, Social Medicine,
Emergency Medicine and Disaster Medicine. It participates in increasing
the quality of organisational structure of medical units, formations and
facilities. It elaborates their operation procedures and principles of their
management in peacetime as well as in emergency situations.
The Department provides expert activities and elaborates data and proposals
from these areas for concept-making bodies of the Czech Army Medical
Service. The Department analyzes NATO regulations and directives
and recommends their introduction in practice as well as in teaching process.
It provides consultations for field leading officers of the Military Medical
Service. The Department cooperates with civilian institutions, namely,
with the bodies of the Ministry of Health of the Czech Republic in the issues
concerning the cooperation between civilian and military medical service
in extraordinary situations. It ensures publication activities focused
on educational work requirements and on presenting scientific information.
The Department is in charge of the education of talented students within
the framework of students´ scientific and professional activities. It
participates in the solution of assignments within the organizational structure
of the military health care in peacetime. It is the consultation and expert
workplace in the branch of General and Emergency Medicine for the Army
of the Czech Republic.
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DEPARTMENT OF MILITARY HEALTH SERVICE ORGANIZATION
DEPARTMENT OF MILITARY HEALTH
SERVICE ORGANIZATION
BLANAŘ Roman
HUMLÍČEK Vojtěch (Head of the Department)
MALÝ Vladimír
MRVEČKA Petr
POTÁČ Michal
PSUTKA Jan (Head of the Group)
RŮŽIČKA Milan (Head of the Group)
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
Technicians
WITT Petr
[email protected]
MÍŠKOVÁ Leona
[email protected]
The Department of Military Health Service Organization is the primary
department which offers military and professional training and education
for students of medicine, pharmacy, military medical management, as well as
for paramedical personnel to the extent necessary for the execution of their
duties in a crisis and wartime health care system. It organizes postgraduate
education for military doctors, pharmacists and bachelors in advanced
courses. It offers specialized training in the field of military health service
administration and management. It is responsible for providing career
courses to military medical personnel.
The subject called "Organization and Tactics of Military Medical Service"
familiarizes students with the activities of the Medical Service in combat
conditions, with the assignments and principals of medical support to troops,
the organizational structure of the military health service in combat,
the operation of particular medical establishments and the principles
of human rights – in particular those defined by the Geneva Convention.
The department carries out training in medical support planning, in working
with map, deployment of field medical facilities, calculation of medical
casualties and the Military Medical Service management.
Other subjects provide students with knowledge in tactic, logistics,
communications, military engineering, topography, and NBC defence. All
these subjects are a part of the general military education of Czech Army
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DEPARTMENT OF MILITARY HEALTH SERVICE ORGANIZATION
professionals and are prerequisites of mastering the subject of military
medicine.
The department teaches disaster medicine, mainly focused on planning,
administration, management and evacuation.
The department serves as a coordinating centre for the field of research
work in the discipline of the Military Medical Service Organization
and Management. It participates in achieving a better quality of organization
in medical
units,
formations,
facilities,
operational
regulations,
and management methods in foreign opeations. It sets out the basic
materials and proposals from the above – mentioned areas for the Czech
Army Medical Service authorities.
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DEPARTMENT OF MILITARY HYGIENE
BEDNARČÍK Peter (Head of the Group)
FAJFROVÁ Jana (Head of the Group)
HLÚBIK Pavol (Head of the Department)
HUSÁROVÁ Michaela
PAVLÍK Vladimír
STŘÍTECKÁ Hana
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
Technicians
PEREGRINOVÁ Jitka
[email protected]
PÍRKOVÁ Jitka
[email protected]
ČMEDLOVÁ Pavlína (maternity leave)
DOHNALOVÁ Lucie
DUŠKOVÁ Klára (maternity leave, since 01 October
2013)
FAJFROVÁ Jana (till 18 September 2013)
HUSÁROVÁ Michaela
HYŠPLER Pavel
LASTIČ Miroslav
MALIŠOVÁ Zuzana
OSLADIL Tomáš
SALAJKOVÁ Šárka (since 01 October 2013)
ŠMÍDOVÁ Petra (till 01 August 2013)
VAŠINA Libor
ZMRZLÁ Hana
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
The Department of Military Hygiene is divided into two relatively
independent groups, the work of which is interconnected and it complexly
covers the basic issues of the relation of life and job environment to
the health of the individual.
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a)
In the area of Hygiene of Nutrition and Occupational Hygiene,
attention is paid namely to the incidence and prevalence of risk
factors of non-infectious diseases of mass incidence, rational food,
catering of troops in peacetime and wartime conditions –
emergency food rations, assessment of the proper received and
consumed energy. Occupational Hygiene is focused above all
on response of the organism to work in protective clothing and
severe climatic conditions and on evaluation of the degree of risk
connected with environment contamination.
b)
The Group of Communal Hygiene is oriented on the analysis
of selected physical and chemical factors of external environment
in the conditions of the Army of the Czech Republic (ACR) It
studies the possibilities of use of chemical substances
for disinfection effects.
Pedagogical activities of the Department of Military Hygiene were and still
are considerably wide. The Department fully participates in a basic pregraduate and post-graduate education of military doctors and in co-operation
with the Institute for Postgraduate Medical Education in Prague; it takes part
in the preparation of civilian physicians. The pre-graduate education pays
attention to the students of the 3rd year of Pharmacy, the 4th and 5th year
of Stomatology and especially to the students of the 5th and 6th year
of General Medicine. The Department of Military Hygiene members
participate in teaching basic warrants officers´ courses, commanders
in reserve courses, recruited nurse’s courses.
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DEPARTMENT OF PUBLIC HEALTH
ANTOŠ Karel
FUSEK Josef
HALAJČUK Tomáš
HLAVÁČKOVÁ Hana
HRSTKA Zdeněk (Head of the Group)
JANOUCH Jindřich
JAREŠOVÁ Lucie
JEŽEK Bruno
KULICH Marek
LAŠÁK Petr (Head of the Group)
PROCHÁZKA Miroslav (Head of the Department)
SOUKUP Ondřej
VANĚK Jan
ŽĎÁROVÁ KARASOVÁ Jana (Head of the Group)
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
Educational and Research Staff / Part time
PETRÁNEK Karel
HEJČOVÁ Jaroslava
[email protected]
The primary focus of the Department of Public Health (K-309) is aimed
at the integration of health care, pharmaceutical and managerial branches
to efficiently support the Medical Service of the Czech Army, particularly
in the field of disaster medicine and emergency planning, and education
of medical and non-medical healthcare personnel in lifelong learning
programs.
The department consists of three groups – the Healthcare Management
Group, the Military Pharmacy Group and the Fitness Preparation Group.
Teaching activities are one of department’s main tasks. The department
takes part in undergraduate study programs in military medicine, military
pharmacy and military emergency response. In addition, teachers participate
in the courses and training programs in health care management, medical
emergency planning, crisis stress management, bio-informatics and
statistics, information and computer technology, health economics, medical
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law and military career courses (basic officer course, senior officer course).
The department also participates in preparation of medical troops for foreign
missions.
Research activities play an important role. The research is oriented
towards process modelling, particularly in the context of healthcare facilities,
emergency situations and major incidents, geographical information systems
in emergency planning and pre hospital medical care, and medical
visualization. Members of the department concentrate on the development
and application of information technologies in all the mentioned fields. By
actively participating in both local and international conferences,
the department has established valuable co-operations with local and foreign
universities.
The department has been involved in international projects creating
centres and methodologies for healthcare management education and
for regional healthcare policies.
Department’s research projects have been supported by the Czech
Science Foundation, Foundation of Ministry of Health and Foundation
of Ministry of Defence.
RESEARCH PROJECTS
GAP303/12/0611)
of cognitive functions will be compared to the effects of a model drug and
standard therapeutics (tacrine, donepezil, rivastigmine). Proposed study can
contribute to the increase of the effectiveness of the treatment of Alzheimer`s
disease.
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Prehospital emergency care efficiency
Procházka, M., Halajčuk, T., Hrstka, Z., Ježek, B., Vaněk, J., Mašek, J.
The main research subject of the project is assessment of suitable criteria
of Emergency Medical Services (EMS) efficiency evaluation. As a part
of the project an analysis of the EMS of Kralovehradecky region will be
performed aimed at the economic efficiency as seen by individual EMS
stakeholders (health insurance companies, EMS, regional government,
Ministry of Health Care), at the EMS medical effects and at the readiness
of the EMS in conjunction with the plan of the region coverage by EMS
bases. To assess the aptness of the economic efficiency criteria standard
economic indicators used in medical facilities will be employed to determine
the criteria suitable for EMS providers. The medical effects criteria will be
established in a retrospective analysis of the EMS response data.
The readiness of the EMS in the region of interest will be considered by
criteria extracted from the data on EMS responses including GPS data
processed in GIS.
Preparation and biological evaluation of new therapeutics against
to pesticides
Kuča, K., Žďárová Karasová, J., Pohanka, M., Jun, D.
The main aim of this project is to search for new and convenient
therapeutics that will be more effective in therapy of pesticide poisoning
(pesticides
are
commonly
used
organophosphate
inhibitors
of cholinesterases). New structures will be determined by using highly
sophistic methodology: molecular design. Predicted structures and their
analogues will be synthesized. Their therapeutic potency will be tested
in in vitro studies. The acetylcholinesterase reactivators with the highest
reactivation potency will be chosen into in vivo tests. During this
development process other important data such as LD50 of newly
synthesized therapeutics, biochemical studies and pharmacokinetics studies
(distribution of newly prepared therapeutics and their ability to penetrate
through the blood-brain barrier into central nervous system) will be also
replenished. If some effective candidates will be found, subsequent
cooperation with foreign institutes is presumed.
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DEPARTMENT OF RADIOBIOLOGY
ŠINKOROVÁ Zuzana
TICHÝ Aleš
VÁVROVÁ Jiřina (Head of the Department)
ZÁRYBNICKÁ Lenka
[email protected]
[email protected]
[email protected]
[email protected]
Technicians
MERVARTOVÁ Lenka
PRŮCHOVÁ Šárka
[email protected]
[email protected]
ĎURIŠOVÁ Kamila
HLÁVKA Aleš
KAŠAOVÁ Linda
KMOCHOVÁ Adéla (since 01 October 2013)
LALÁKOVÁ Lucie (till 12 August 2013)
NOVOTNÁ Eva
[email protected]
[email protected]
The Department of Radiobiology was established at Purkyně Military
Medical Research and Postgraduate Institute on September the 1st 1963.
The first chief of the department became Colonel Prof. MUDr. Josef Mráz,
CSc., who was in 1968 appointed the first professor of military radiobiology
of the Charles University. The main tasks of the department are teaching and
research activities, which are closely connected.
In the field of research, the experimental work includes histology and
cytology, in vitro methods, methods of proteomic analysis and methods
of flow cytometry. Individual technological units allow in vitro and in vivo
observation of post-radiation mechanisms on molecular, cellular, and organ
levels.
Military research is focused on early diagnosis and therapy of postradiation damage in the main objective of the department. The aim
of investigation in the medium-term horizon is discovery and practical
introduction of bio-dosimeter markers as well as continuous renewal
of decontamination agents for the Army of CR. Mutual cooperation with other
NBC research workplaces also remains an integral part of our research
activities. Cooperation with civilian workplaces at the Faculty of Medicine and
the University Hospital in Hradec Králové is focused on radiation oncology.
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The Department of Radiobiology takes part in military medical-specialist
education in the form of pre-gradual and post-gradual education mainly
in doctoral studies. The main educational activity is lecturing military
radiobiology. The main topics are: the nuclear weapons effects on the living
organism, the possibilities of the protection and medical treatment
of irradiated persons. Other special military issues are disaster medicine,
NBC protection etc., which are taught at the Faculty of Military Health
Sciences, including the topics, which are presented by the instructors of our
department.
RESEARCH PROJECTS
Phosphoproteomic analysis of leukaemic cells after irradiation
Tichý, A.
GPP206/12/P338)
Phosphorylation is one of the most important post-translational
modifications, which affects protein structure, function, and localization,
regulating majority of biochemical processes. In our previous work we were
engaged with molecular mechanisms of response of leukaemic cells MOLT-4
(p53-positive) and HL-60 (p53-negative)to ionising radiation. Submitted
project proposes to characterize phosphoproteome of the mentioned cells,
i.e. to identify phosphoproteins which are involved in radiation-induced
signaling using tandem mass spectrometry, and to propose the potential
biodosimetric markers. To date, no study has been published
in the presented area mainly due to a very low abundance
of phosphoproteins in the cell and due to insufficient ionization during MS
analysis (acidic and hydrophilic character) compared to non-modified
proteins. Therefore we will employ the newest methods for selective
enrichment of phosphopeptides (bioaffinity chromatography) and recent
knowledge to increase enrichment efficiency (methylation, pH adjustment
etc.).
Radio-sensibilization of MOLT-4 and SAOS-2 cell lines by DNA repair
inhibition: Phosphoproteomic analysis of irradiated cancer cells
Šalovská, B., Tichý, A.
Supported by Grant Agency of Charles University, 2013–2013 (Project No.:
GAUK 2013)
The project is based on the study of phosphorylation – one of the most
considerable post-translational modifications. To induce phosphorylation we
employ ionizing radiation, which is used in radiotherapy of cancer since its
capable of induction of DNA damage and apoptosis. In order to increase
radiosensitivity, it is often combined with various radiosensitizers
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Hence, the main goal is to compare the effect of three radiosensitizers –
KU55339, NU7441, and VE-821 that specifically inhibit key kinases
regulating DNA repair after irradiation – ataxia-telangiectasia mutated kinase,
DNA-dependent protein kinase a ATM-Rad3-related kinase. Each of these
kinases phosphorylates a number of other substrates, some of them
specifically and some redundantly and triggers a specific signalling cascade.
Consequently, inhibition of DNA repair enzymes increases apoptosis
and allows eradication of a cancer cells. Since we use a specific inhibitor
for each particular kinase, we aim to exploit mass spectrometry
for identification and quantification of proteins involved in the mentioned
pathways and to investigate their role in the p53-negative cellular
environment.
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DEPARTMENT OF TOXICOLOGY
BAJGAR Jiří
CABAL Jiří (Head of the Group)
KASSA Jiří (Head of the Department)
KORÁBEČNÝ Jan
KRAČMAROVÁ Alžběta
MISÍK Jan
MUSÍLEK Kamil
SVOBODOVÁ Hana
ŠEPSOVÁ Vendula
ŠTĚTINA Rudolf (Head of the Group)
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
Technicians
RESLOVÁ Eva
ŠKRANCOVÁ Věra
UHLÍŘOVÁ Jana
ANDRŠ Martin (since 01 October 2013)
BENEK Ondřej
COUFALOVÁ Klára (till 31 May 2013)
JÍLKOVÁ Martina
JOŠT Petr
KAŠPÁREK Aleš (till 01 October 2013)
MISÍK Jan (till 24 January 2013)
NEPOVIMOVÁ Eugenie (since 01 October 2013)
PAVLÍK Michal
PAVLÍKOVÁ Růžena
PAVLIŠ Oto
PEJCHAL Jaroslav
ŠEPSOVÁ Vendula
ŠPILOVSKÁ Katarína
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[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
VOBORNÍKOVÁ Irena
ZEMEK Filip
[email protected]
The Department was established in 1951. Since then, as an integral part
of the Faculty of Military Health Sciences, it has been involved in education
and scientific research work on chemical warfare agents for defensive and
protective purposes only. It comprises two laboratory groups – a biochemical
(biochemical laboratory, laboratory of organic synthesis, analytical
laboratory, decontamination laboratory) and an experimental therapy group
(toxicological laboratory, pharmacological laboratory, neurophysiological
laboratory, neurobehavioral laboratory, genotoxicological laboratory). This
structure permits the complex study of highly toxic substances including
chemical warfare agents with aims to determine their action on biochemical,
neurobehavioral, histochemical, pharmacological and neurophysiological
level, to study and develop antidotes, to analyse all types of samples
with respect to the presence of known chemical warfare agents, to test
decontamination effectiveness of developed and field decontamination kits.
Present scientific research projects are focused on therapeutic, prophylactic
and protective measures against the most toxic chemical warfare agents.
Special attention has been paid to the most recent and most dangerous
nerve agents and mustards. The main educational activity task was to give
lectures for undergraduate and post-graduate studies dealing with problems
of biological effects of real and potencial chemical warfare agents,
the possibilities of the medical and chemical protection against them and
the approaches to medical care of persons intoxicated with chemical warfare
agents, especially nerve agents. The Department of Toxicology also
participates in the teaching of toxicology in disaster medicine.
RESEARCH PROJECTS
GAP303/12/0611)
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of cognitive functions will be compared to the effects of a model drug
and standard therapeutics (tacrine, donepezil, rivastigmine). Proposed study
can contribute to the increase of the effectiveness of the treatment
of Alzheimer`s disease.
COOPERATION
In 2013, the Department of Toxicology has continued in the cooperation
with various research institutes (the National Poison Control Centre, Military
Medical Academy, Belgrade – Republic of Serbia, Medicinal Science
Division, Korea Research Institute of Chemical Technology, Taejon – Korea,
Institute for Medical Research and Occupational Health, Zagreb – Croatia,
Bundeswehr Institute of Pharmacology and Toxicology, Munich – Germany,
Florida International University, Herbert Wertheim College of Medicine
in USA, University of St. Andrew, School of Biology in United Kingdom, UAE
University, Faculty of Medical Research Sciences in United Arabian
Emirates, Semmelweis University, Faculty of Pharmacy in Hungary, Institute
de Recherches Biomédical des Armeés in France) in the field
of development of prophylactic and therapeutical means against nerve
agents and organophosphorous insecticides. The cooperation has been
mostly characterized by the exchange of scientific information. Within
the frame of the work dealing with the identification of the mechanisms
of chemoprevention in the initial phases of mutageneses and carcinogenesis,
the Department of Toxicology has also continued in cooperation
with the Institute Nutrition Research in Oslo (Norway) and the Institute
of Experimental Oncology and the Slovak Health Care University
in Bratislava (Slovak Republic). The cooperation with Department of Organic
Chemistry, Institute of Chemistry, P. J. Šafárik University in Košice (Slovak
Republik), Department of Biophysics, Institute of Experimental Physics,
Slovak Academy of Sciences in Košice (Slovak Republic) and Faculty
of Chemical and Food Technology, Slovak Technical University in Bratislava
(Slovak Republic) is continuing in the field of the development of new
potential therapeutic means against Alzheimer disease.
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INSTITUTE OF MOLECULAR PATHOLOGY
BALONOVÁ Lucie
KLIMENTOVÁ Jana
KROČOVÁ Zuzana (Head of the Group)
LENČO Juraj
LINK Marek
MACELA Aleš (Prof. Emerit.)
PÁVKOVÁ Ivona
ŘEHULKA Pavel (Head of the Group)
STULÍK Jiří (Head of the Institute)
ŠPIDLOVÁ Petra
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
Technicians
LUKŠÍKOVÁ Lenka (maternity leave)
ŠAFÁŘOVÁ Mária
[email protected]
[email protected]
FORETOVÁ Zdenka
[email protected]
DAŇKOVÁ Věra
DRESLER Jiří (till 13 September 2013)
FABRIK Ivo
FUČÍKOVÁ Alena (till 27 September 2013)
HOSTÝNKOVÁ Veronika
NEUBAUEROVÁ Věra
PLZÁKOVÁ Lenka (since 01 October 2013)
PUTZOVÁ Daniela
SCHMIDT Monika
ŠENITKOVÁ Iva
VAJRYCHOVÁ Marie
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[email protected]
[email protected]
[email protected]
[email protected]
[email protected]
senitkovpmfhk.cza
The Institute of Molecular Pathology, as one of the successors
of the Institute of Radiobiology and Molecular Pathology, is a research centre
focused on the application of advanced technologies of functional genomics
to bio-medical defence research. Scientific work is preferably aimed at the
studies of the host-pathogen interactions at the molecular level.
The objectives of this research splits in three main topics: biomolecular
signatures of biological agents potentially abused for the military, terroristic
or bio-crime acts, intracellular fate of ingested microbes and finally the
modulation of host cell signalling and gene expression by ongoing infection.
The favourite microbial model is live vaccine strain of Francisella tularensis,
a gram-negative facultative intracellular bacterial pathogen from the gamma
subdivision of Proteobacteriae.
The second branch of the research involves the clinical studies utilizing
the post-genomic approaches for identification of new biomarkers of different
pathological processes. Laboratories of the Institute are currently equipped
for realization of complete classical and shotgun proteomic analyses.
The materials for analyses are prepared in the Institute’s tissue culture and
microbiological labs. In parallel, the basic search for gene expression can be
performed using quantitative real-time PCR technology. The established
technologies enable researchers, Ph.D. students, and under-graduate
students to realize complex studies oriented on the analyses of living system
response to external (and internal, modulatory) signals encompassing
the chemicals, biologically active bio-molecules, physical influences
(temperature, radiation, etc.), and microorganisms.
During the year 2008 the Institute traditionally cooperated with the military
medical and research facility in Sweden (FOI NBC-Defence, Umea)
on preparation of Francisella tularensis knock-outs. The further scientific
contacts involved National Center for Glycomics and Glycoproteomics,
Department of Chemistry, Indiana University, USA – mass spectrometry
analysis of bacterial glycoproteins, Unité de Pathogénie des Infections
Systémiques, Faculté de Médecine, Necker-Enfants Malades, Paris, France
– comparative proteomic studies of Francisella tularensis deletion mutants,
U.S. Army Medical Research Institute of Infectious Disease (Fort Detrick,
USA) – preparation and testing of bacterial proteins with immunostimulatory
potential and, finally Department of Microbiology and Parasitology, University
of Rijeka – microscopical analysis of microbial intracellular trafficking,
Molecular Infection Medicine, University of Umea, Sweden – analysis
of host-pathogen interactions.
Within the frame of the Czech Republic, the Institute has useful contacts
with the Institute of Microbiology, Czech Academy of Science, Prague,
the Faculty of Science, Charles University, Prague, the University Hospital
in Hradec Králové, Department of Pharmacology of Medical Faculty
in Hradec Králové, Department of Oncological and Experimental Pathology
Masaryk Memorial Cancer Institute, Brno and Veterinary Research Institute
in Brno.
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The financial support for research activities performed in the collaboration
with above-mentioned Institutes comes from the programmes and projects
of Czech Grant Agencies and Ministry of Defence. Currently, the Institute for
Molecular Pathology has 11 full-time permanent employees, 9 scientists, 1
technician and 1 administrative worker. The Institute has currently 10 PhD
students and, furthermore, several undergraduates have been working
on their diploma thesis in the Institute.
RESEARCH PROJECTS
Characterization of the diagnostic potential of native polypeptides in
amniotic fluid
Lenčo, J.
Preterm premature rupture of membranes (PPROM) is a principal cause
of preterm births and considerably increases perinatal morbidity and
mortality. The main reason is the causal link with intraamniotic infection (IAI),
which occurs in 40–60 % of PPROM patients. The most serious cases of IAI
may result in fetal inflammatory response (FIRS) and cause permanent
health consequences for the newborn or end up by the death of the fetus.
FIRS is very often subclinical and thus frequently remains undetected.
Currently, there is no tool for its precise prenatal diagnostics available.
The project is focused on characterization of the diagnostic potential
of native amniotic fluid polypeptides with regard to detection of IAI and FIRS.
Identification of novel Francisella tularensis targets for subunit vaccine
development
Stulík, J., Worsham, P.
Supported by the Defense Threat Reduction Agency, 2011–2014 (Project
No.: D-CZ-10-0001)
To develop a subunit vaccine for tularemia. Specifically, this project
focuses on (1) the identification of surface associated or secreted virulence
factors from F. tularensis using immunoproteomic approaches (2) cloning
and expression of these gene products, (3) confirming the role
of the selected targets in virulence, and (4) assessing these proteins
as protective antigens in animal models.
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(Project No.: VF20122015024)
toxins from natural matrices, and the procedures for their identification
and typing. In the case of bacteria and viruses are designed following
the methodological procedures and specific technological and laboratory
units: the acquisition and cultivation of biological agents, isolation of genome
and plasmid DNA, or RNA in the case of a virus, the methodology
and procedures for the preparation of samples of bacterial and viral nucleic
acids from complex matrices, design of qPCR primers, probes
and the reaction conditions and testing and validation of the proposed
methods and procedures for the identification of biological agents. For the
detection of low molecular weight toxins will be used high performance liquid
chromatography coupled with tandem mass spectrometry and for detection
and identification of protein toxins will be used mass spectrometric method
SRM (Selected reaction monitoring).
Proteome analysis of the interaction of host cell with intracellular
pathogen
Stulík, J.
(Project No.: 7AMB12GR038)
Project Mobility Czech Republic – Greece. The major aim
of the proposed project is the common exploitation of advanced proteome
high-throughput technologies, established in different scope in both
laboratories, for identification of key host cell protein molecules whose
quantity ad/or posttranslational modification is modulated by the early phase
of host-pathogen interaction. Furthermore using bioinformatic tools
the probable functions and the role of these identified proteins in the host
protective response against infection will be predicted.
Targeted proteomic analysis in hypertrophic cardiomyopathy
Stulík, J., Fučíková, A.
The basic objective of the proposed project is to verify the analytical
potential of selected biomarkers of peripheral blood for diagnostics
of hypertrophic cardiomyopathy. In our previous study, we used quantitative
proteomics to identify 40 proteins in plasma. The plasma concentrations
of these proteins were significantly different compare to control group.
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The scope of the proposed project is the verification and validation
of the concentration of these proteins in peripheral blood of patients
with hypertrophic cardiomyopathy; the comparison of the results
with the healthy population and other diseases that are accompanied by
structural changes in the myocardium (dilated cardiomyopathy, ischemic
heart disease, arterial hypertension and aortic stenosis). The project will use
commercially available kits based on the detection and quantification using
antibodies and antibody-independent method for proteomic SRM (Selected
Reaction Monitoring).
The role of B cells during natural and adaptive phase of immune
response against Francisella tularensis infection in mice
Kročová, Z.
GAP302/11/1631)
Tularemia is a zoonotic infection with high infectivity and high morbidity.
The etiological agent of tularemia is Francisella tularensis, an intracellular
pathogen on all major lists of potential bioterroristic agents. The live vaccine
strain without the license for human use is still the only problematic tool
for the immunoprophylaxis. In spite of a growing number of studies dedicated
to immunity against tularemia, the mechanisms participating in the protective
response remain mostly unknown. Especially the role of B cells and specific
antibodies is a recently hot topic of debate. For this reason the proposal
of this project covers the aims concerning the mechanisms by which B cells
and antibodies participate in protective response, e.g. antigen presenting
function, production of specific antibodies during the T-independent phase
of innate response, B cell mediated immunological memory and the
existence of an analogy of ADCC where bacteria are the targets. No direct
experimental evidence exists for the participation of these phenomena
in protective immunity against tularemia.
dysfunction
GAP304/10/1161)
and subsequently initiate intracellular signaling. This can be mediated by Aktth
GSK3 pathway and PGE metabolism, leading to T cell dysfunction
and apoptosis. This proposal utilizes state-of the art proteomic approach to
to the elucidation of mechanisms involved in CD4 T cell dysfunction
and death in such diseases as chickenpox and AIDS.
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VIVARIUM
VIVARIUM
PAVLÍK Michal (Head of the Department)
[email protected]
Technicians
BOCKOVÁ Irenea (Head of the Group)
ETFLAIŠOVÁ Petra
JUNKOVÁ Irena
PUDÍKOVÁ Margita
SLAVÍK Jaroslav
The Vivarium at the Faculty of Military Health Sciences of the University
of Defence fulfils science, research and teaching tasks of the departments
and specialized workplaces of the Faculty of Military Health Sciences.
The vivarium is subordinated to the Department of Teaching support.
The separate vivarium for mice and sewer-rats is a part
of the Department of Toxicology.
From the point of view of the capacity the Faculty of Military Health
Sciences is able to carry out experiments, place and take care of laboratory
mice, sewer-rats, guinea-pigs, rabbits, pigs or mini pigs. In the area
of the vivarium there are also laboratory workplaces and operating theatres,
which are equipped for experiments on laboratory animals. All studies have
to be allowed by the Ethical Board of the Faculty of the Military Health
Sciences fully in compliance with the legal standards of the protection
against cruelty to animals.
The vivarium with the operating block is intesively used above all
for experiments on large experimental animals. The courses BATLS
and BARTS are held there. During the courses different model situations
and cases of emergency medicine are performed for military doctors
and participants of foreign mission including war injuries on dead and live
experimental animals.
On 30 December 2010 the vivarium was accredited for use again for 5
years (till 30 December 2015) by the Central Board for Animal Protection .
The above-mentioned range of the activities shows that it is necessary
to time work and also co-ordinate it personally including permanent presence
of a veterinary surgeon, veterinary technicians and breeders of laboratory
animals.
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VISITS ABROAD
VISITORS TO THE FACULTY OF MILITARY
HEALTH SCIENCES
Austria
Ernst Pittenauer (Vienna) – Scientific
December 2013–06 December 2013
collaboration,
02
Greece
Katerina Arvaniti (Iraklion) – Training in lipid raft isolation and
microgradient separation of peptides, 14 July 2013–20 July
2013
Hungary
Anita Jekö (Budapest) – Erasmus, 01 November 2013–01
February 2014
VISITS ABROAD
Austria
Chlíbek, R. (15th ISW-TBE Meeting will Take Place, Vienna, 31
January 2013–01 February 2013)
Klein, L. (15th European Burns Association Congress, Vienna,
27 August 2013–31 August 2013)
Vajrychová, M. (Late summer practical proteomic seminar,
Vienna, 02 September 2013–03 September 2013)
Žďárová Karasová, J. (21th WCN 2013, Vienna, 21 September
2013–26 September 2013)
Belgium
Boštík, P. (CapTech ESM04 EDA meeting, Brussels, 07
November 2013–08 November 2013)
Chlíbek, R. (Combination Vaccines Academy, Brussels, 09 May
2013–10 May 2013)
Kassa, J. (34th NATO CBRN Medical Working Group Meeting,
Brussels, 10 February 2013–15 February 2013)
Brazil
Boštík, P. (1st CBRN Threat Seminar, Rio de Janeiro, 26
November 2013–01 December 2013)
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VISITS ABROAD
Bulgaria
Halajčuk, T. (12th International Conference Economy &
Business, Sunny Beach, 01 September 2013–05 September
2013)
Procházka, M. (12th International Conference Economy &
Business, Sunny Beach, 01 September 2013–05 September
2013)
France
Zárybnická, L. (InnovaCom: Education for Competitiveness,
Paris, 20 November 2013–20 November 2013)
Zárybnická, L. (Internhip of the Operational Programme
”Education for Competitiveness“, Paris, 29 October 2013–28
November 2013)
Germany
Boštík, P. (CapTech ESM04 EDA meeting, Ottobrunn, 18 June
2013–20 June 2013)
Dohnalová, L. (International Summer Lab (ISL) – Course "Food
Process
Design",
University
of
Applied
Sciences,
Quakenbrueck, 07 July 2013–19 July 2013)
Chlíbek, R. (2nd Conference on Controversies in Vaccination in
Adults, Munich, 14 February 2013–17 February 2013)
Kassa, J. (14th International Medical Chemical Defence
Conference, Munich, 23 April 2013–25 April 2013)
Musílek, K. (14th International Medical Chemical Defence
Conference, Munich, 23 April 2013–25 December 2013)
Greece
Stulík, J. (Working Meeting at Department of Chemistry,
University of Crete, Iraklion, 13 November 2013–16 November
2013)
Hungary
Kubelková, K. (EFIS–EJI Sympozium IMPULSE, Matrahaza, 31
August 2013–04 September 2013)
China
Šepsová, V. (14th International Symposium on Cholinergic
Mechanisms, Hangzhou, 05 May 2013–09 May 2013)
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VISITS ABROAD
Israel
Boštík, P. (10th International Consequence Management
Seminar, Tel Aviv, 06 October 2013–10 October 2013)
Páral, J. (4th World Congress for the Advancement of Surgery,
Tel Aviv, 27 October 2013–31 October 2013)
Italy
Chlíbek, R. (31st Meeting of the European Society for Paediatric
Infectious Diseases, Milan, 28 May 2013–31 May 2013)
Kassa, J. (AD/PD™ 2013: 11th International Conference
on Alzheimer’s and Parkinson’s Diseases, Florence, 06 March
2013–10 March 2013)
Kročová, Z. (15th International Congress of Immunology, Milan,
22 August 2013–27 September 2013)
Kubelková, K. (15th International Congress of Immunology,
Milan, 22 August 2013–28 August 2013)
Lochman, P. (10th International Gastric Cancer Congress,
Verona, 18 June 2013–22 June 2013)
Misík, J. (AD/PD™ 2013: 11th International Conference
on Alzheimer’s and Parkinson’s Diseases, Florence, 06 March
2013–10 March 2013)
Musílek, K. (AD/PD™ 2013: 11th International Conference on
Alzheimer’s and Parkinson’s Diseases, Florence, 06 March
2013–10 March 2013)
Smetana, J. (31st Meeting of the European Society
for Paediatric Infectious Diseases, Milan, 28 May 2013–31 May
2013)
Šepsová, V. (AD/PD™ 2013: 11th International Conference on
Alzheimer’s and Parkinson’s Diseases, Florence, 06 March
2013–10 March 2013)
Žďárová Karasová, J. (AD/PD™ 2013: 11th International
Conference on Alzheimer’s and Parkinson’s Diseases, Florence,
06 March 2013–10 March 2013)
Japan
Vajrychová, M. (12th World congress HUPO, Yokohama, 12
September 2013–19 September 2013)
Norway
Klein, L. (Worshop and Seminar on Health
Management, Oslo, 09 June 2013–14 June 2013)
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Disaster
VISITS ABROAD
Poland
Hlúbik, P. (8th National Scientific Conference, Biala Podlaska,
03 September 2013–06 September 2013)
Chlíbek, R. (6th Pneumo Surveillence Workschop, Kraków, 16
April 2013–18 May 2013)
Kročová, Z. (ESF-EMBO Symposium with support from EFIS: B
Cells from Bedside to Bench and Back Again, Pultusk, 02
Republic of Korea
Kuča, K. (Korean Research Institute of Chemical Technology,
Daejon, 15 October 2013–15 October 2013)
Serbia
Chlíbek, R. (3rd CEEPAG Meeting Agenda, Belgrade, 29
January 2013–31 January 2013)
Slovakia
Chlíbek, R. (14th Slovak Immunisation Congress, Štrbské Pleso,
17 January 2013–19 January 2013)
Chlíbek, R. (Adolescent Vaccination, Bratislava, 25 April 2013–
27 April 2013)
Chlíbek, R. (17th Slovak-Czech Congress on Infections
Diseases, Poprad, 13 June 2013–15 June 2013)
Chlíbek, R. (10th Slovak Paediatric Congress, Bratislava, 25
April 2013–27 April 2013)
Kubelková, K. (Virological Institute in Bratislava, Bratislava, 11
March 2013–22 March 2013)
Pavlík, V. (Living Conditions and Health, Nový Smokovec, 23
Svobodová, H. (Genetic toxicology and prevention of cancer,
Smolenice, 13 October 2013–16 October 2013)
Svobodová, H. (FEBS workshop – Nucleotide excision repair
and interstrand crosslink repair, Smolenice, 09 June 2013–13
June 2013)
Šinkorová, Z. (Disaster Crisis Management, Žilina, 05 June
2013–06 June 2013)
Štětina, R. (FEBS workshop – Nucleotide excision repair and
interstrand crosslink repair, Smolenice, 09 June 2013–13 June
2013)
Šubrt, Z. (67th Surgery Day of Kostlivy, Bratislava, 06 December
2013–06 December 2013)
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VISITS ABROAD
South Africa
Chlíbek, R. (8th World Congress of the World Society
for Pediatric Infectious Diseases WSPID, Cape-town, 18
Smetana, J. (8th World Congress of the World Society
for Pediatric Infectious Diseases WSPID, Cape-Town, 18
Spain
Boštíková, V. (CDC Advisory Board, Malaga, 07 October 2013–
11 October 2013)
Kassa, J. (26th ECNP Congress, Barcelona, 05 October 2013–
10 October 2013)
Misík, J. (26th ECNP Congress, Barcelona, 05 October 2013–10
October 2013)
Pohanka, M. (26th ECNP Congress, Barcelona, 05 October
2013–10 October 2013)
Střítecká, H. (20th International Congress of Nutrition, Granada,
15 September 2013–20 September 2013)
Špliňo, M. (CDC Advisory Board, Malaga, 08 September 2013–
13 September 2013)
Sweden
Kupsa, T. (18th Congress of European Hematology Association
(EHA), Stockholm, 12 June 2013–16 June 2013)
Šepsová, V. (Shalgagreska Institut University Gothenburg,
Gothenburg, 17 November 2013–30 November 2013)
Zárybnická, L. (CELOD: Cellular Effects of Low Doses and Low
Dose-Rates with Focus on DNA Damage and Stress Response,
Stockholm, 21 April 2013–03 May 2013)
Switzerland
Šmejkal, K. (AOTrauma Masters Course – Complications and
Complex Fractures, Davos, 08 December 2013–13 December
2013)
Turkey
Horáček, J. (4th International Congress on Leukemia
Lymphoma Myeloma (ICLLM), Istanbul, 21 May 2013–26 May
2013)
Chlíbek, R. (EURIT Regional Advisory Board on Adult
Vaccination against Pneumococcal Diseases, Istanbul, 25
October 2013–27 October 2013)
Stulík, J. (International Symposium on Francisella tularensis and
Tularemia, Urgup, 18 June 2013–23 June 2013)
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VISITS ABROAD
Špidlová, P. (International Symposium on Francisella tularensis
and Tularemia, Urgup, 18 June 2013–23 June 2013)
United Kingdom
Hlúbik, P. (ECO 2013, Liverpool, 12 May 2013–16 May 2013)
Jebavý, L. (39th Annual Meeting of the European Group
for Blood and Marrow Transplantation (EBMT), London, 06 April
2013–10 April 2013)
Soukup, O. (Postdoc Intership, St. Andrews, 28 April 2013–18
June 2013)
Střítecká, H. (ECO 2013, Liverpool, 12 May 2013–16 May 2013)
United States
Boštíková, V. (Viral infections, Atlanta, 01 December 2013–09
December 2013)
Horáček, J. (55th Annual Meeting of American Society
of Hematology (ASH), New Orleans, LA, 04 December 2013–12
December 2013)
Korábečný, J. (Neuroscience 2013 – annual meeting SfN, San
Diego, 08 November 2013–14 December 2013)
Kuča, K. (Neuroscience 2013 – annual meeting SfN, San Diego,
08 November 2013–14 November 2013)
Kupsa, T. (55th Annual Meeting of American Society
of Hematology (ASH), New Orleans, LA, 04 December 2013–12
December 2013)
Misík, J. (Neuroscience 2013 – annual meeting SfN, San Diego,
08 November 2013–14 November 2013)
Musílek, K. (Alzheimer´s Association International Conference
2013, Boston, 13 July 2013–18 July 2013)
Pohanka, M. (Modulation of immunization via cholinergic
nervous system using HI-6, Baltimore, 19 November 2013–24
November 2013)
Soukup, O. (Neuroscience 2013 – annual meeting SfN, San
Diego, 08 November 2013–14 November 2013)
Šinkorová, Z. (28th Congress of the International Society
for Advancement of Cytometry – Cyto 2013, San Diego, 19 May
2013–23 May 2013)
Vietnam
Klein, L. (9th Asia-Pacific Burns Conference (ISBI), Hanoi, 31
March 2013–07 April 2013)
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WORKSHOPS, COURSES, RESIDENCIES AT THE FACULTY IN 2013
WORKSHOPS, COURSES, RESIDENCIES
AT THE FACULTY IN 2013
Military Hygiene
Specialized course – Evaluation of workload, 04 November
2013–06 November 2013
Specialized course – Teachings about foodstaf, 02 April 2013–
04 April 2013
Specialized course – Hygienic support to missions, 04 March
2013–06 March 2013
Specialised course – Work environment and occupational
hygiene, job classification, 27 February 2013–27 February 2013
Specialized course – Nutrition support of patients
with overweight and obesity, 11 March 2013–13 March 2013, 25
November 2013–27 November 2013
Specialized course – Obesity, diagnostic possibilities,
psychological aspects, therapeutical approach, 09 September
2013–11 September 2013
Specialised course – Providing personal protective equipment
(PPE), washing, cleaning and disinfective agents and protective
drinks in the workplace, 26 February 2013–26 February 2013
Specialized course – Evaluation of the nutritional state
of the organism, 14 January 2013–16 January 2013
Language Courses
Refresher language courses – English (STANAG 2), 21 October
2013–29 November 2013
Combined language courses – English (STANAG 3), 03
September 2012–31 May 2013, 09 September 2013–30 May
2014
Intensive language courses – English (STANAG 1), 09
September 2013–13 December 2013
Refresher language courses – English (STANAG 1), 09
September 2013–18 October 2013
Medical English conversation course, 11 February 2013–22
February 2013
Combined language courses – French (STANAG 2), 17
September 2012–14 June 2013
Combined language courses – English (STANAG 2), 09
September 2013–30 May 2014
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Military Medical Service Organization
Specialized course of aeromedical evacuation, 16 April 2013–
18 April 2013
Specialized warrent officer’s course for non-medical personnel,
08 April 2013–14 June 2013
Senior staff officer course – Military health service organization
and management, 16 September 2013–27 June 2014, 03
September 2012–14 June 2013
Course for officers – Military health service organization and
management, 07 January 2013–03 May 2013
Special course – characteristics of ACR Military Medical Service
function, 12 February 2013–14 February 2013
MEDEVAC specialized course – Use of helicopter, 07 October
2013–11 October 2013
Purpose course for members of medical service before mission
abroad, 21 January 2013–22 January 2013
Military Epidemiology
Specialized course – Epidemiology of new infectious diseases,
22 January 2013–24 January 2013
Specialized course – Basis in tropical and travel medicine, 05
Specialized course – Infectious diseases prevention, 12
General Medicine
Specialized course – Battlefield Advanced Trauma Life Support
(BATLS), 25 February 2013–27 February 2013, 02 April 2013–
04 April 2013, 04 November 2013–06 November 2013
Specialized course – Teaching methodology of health training,
08 April 2013–12 April 2013
Special course of first aid in the field, 14 January 2013–18
January 2013, 28 January 2013–01 February 2013, 04 February
2013–08 February 2013, 18 February 2013–22 March 2013, 02
September 2013–06 September 2013, 23 September 2013–27
September 2013
Special course of first aid in the field for VO 84, 04 February
2013–08 February 2013
Innovative course – Battlefield Advanced Resuscitation
Techniques and Skills (R-BARTS), 04 March 2013–06 March
2013, 09 September 2013–11 September 2013
Specialized course – Battlefield Advanced Resuscitation
Techniques and Skills (BARTS), 25 March 2013–27 February
2013, 02 April 2013–04 April 2013, 04 November 2013–06
November 2013
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Special course of health training for Military High School
Moravska Trebova, 04 June 2013–06 June 2013, 11 June
2013–13 June 2013, 18 June 2013–20 June 2013
Specialized course – Defibrilators and their operation, 10
January 2013–10 January 2013, 30 April 2013–30 April 2013,
12 September 2013–12 September 2013, 03 October 2013–03
October 2013
Specialized course – Transportation of casualties in the field, 22
April 2013–26 April 2013, 17 June 2013–21 June 2013
Special course of first aid in the field for Police of the Czech
Republic, 15 April 2013–19 April 2013
Special course in extended first aid in the field for the Police
of the Czech Republic (CLS Course), 13 May 2013–24 May
2013
Special course in extended first aid in the field (CLS Course), 18
March 2013–29 March 2013, 03 June 2013–14 June 2013, 07
October 2013–18 October 2013, 18 November 2013–29
November 2013
Special course – Repetitory of extended first aid in field
conditions (R-CLS Course), 11 November 2013–15 November
2013
Innovative course – Battlefield Advanced Trauma Life Support
(R – BATLS), 04 March 2013–06 March 2013, 09 September
2013–11 September 2013
Computing
Special course – MS Access, 28 January 2013–01 February
2013, 30 September 2013–04 October 2013
Special course – MS PowerPoint and Internet, 07 January
2013–11 January 2013, 07 October 2013–11 October 2013
Special course – MS Windows a MS Word, 14 January 2013–18
January 2013
Refresher course in MS Word, 20 May 2013–22 May 2013
Special Course – Statistics and data processing in MS Excel, 18
February 2013–22 February 2013, 11 March 2013–15 March
2013, 03 June 2013–07 June 2013
Molecular Pathology
Specialized course – biosensors for detection of biological and
chemical agents, 11 February 2013–11 February 2013, 11
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Multidisciplinary Studies
Special course – Basis of pharmacology and self-treatment, 18
February 2013–21 February 2013
Special course – psychology and crisis interventions,
management of difficult patients, 11 March 2013–13 March
2013, 14 October 2013–16 October 2013
Preparatory course for entrance examination, 03 June 2013–08
June 2013
Specialized course – Prevention of burn–out syndrom, 11
February 2013–13 February 2013
Specialized course – Dealing with extremely dangerous poisons,
drugs and psychotropic substances, 04 February 2013–07
February 2013, 02 September 2013–05 September 2013, 21
October 2013–22 October 2013
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INTERNATIONAL COOPERATION
Cooperation at the military medical facility level
Brazil
Faculdade de Farmácia, Salvador, Bahia
Universidade Federal de Santa Catarina,
Florianopolis
Bulgaria
Military Medical Academy, Sofia
France
Health Service and Army Research Center
(C.R.S.S.A.), Grenoble
School of the Health Service of the Armies
of Lyon-Bron (E.S.S.A..), Lyon
Germany
Institute of Microbiology of Federal Armed Forces
Medical Academy, Munich
Institute of Pharmacology and Toxicology of
Federal Armed Forces Medical Academy, Munich
India
Pandit Ravishankar Shukla University, Raipur
Poland
Military Institute of Hygiene and Epidemiology,
Warsaw
Serbia
National Poison Control Centre of Military Medical
Academy, Belgrade
Slovakia
Air Forces Hospital, Košice
Central Military Hospital, Ružomberok
Military Health Service, Bratislava
Military Institute of Hygiene and Epidemiology,
Bratislava
Swedish Defence Research Agency, Dr.
Artursson – Department of Threat Assessment,
Division of NBC Defence, Umea
The
Netherlands
Division of Toxicology, TNO Prins Maurits
Laboratory, Rijswijk
Turkey
Gulhane Military Medical Academy, Ankara
Ukraine
Military Medical Corps, Kiev
United Kingdom
Defence Medical Services Training Centre Keogh
Barracks in Aldershot, Ash Vale
DRDC, Suffield
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United States
United States Defense Institute of International
Legal Studies, Newport
Scientific cooperation with civilian institutions abroad (on the basis
of individual agreements and joint projects)
Austria
Baxter, Vienna
Center of Biomolecular Medicine &
Pharmacology, Medical University of Vienna,
Vienna
Institute of Chemical Technologies and Analytics,
Vienna University of Technology, Vienna
Belgium
GlaxoSmithKline Biologicals, Rixensart
Croatia
Department of Microbiology and Parasitology,
University of Rijeka, Rijeka
Institute for Medical Research and Occupational
Health, Zagreb
France
Aventis Pasteur MSD, Lyon
Saint Louis Hospital, Paris
Germany
Department of Solid States Nuclear Physics,
University of Leipzig, Leipzig
Greece
Universit of Crete, Iraklion
Hungary
Semmelweis University, Budapest
Mongolia
National Research Center for Infectious
Diseases, Ministry of Health, Ulaanbaatar
Norway
Department of Nutrition, Medical Faculty,
University of Oslo, Oslo
Poland
WIHE, Dr Zdanowski – Zakład Farmakologii i
Toksykologii, Warsaw
Portugal
University of Coimbra, Department of
Pharmacology, Coimbra
Republic of
Korea
Medicinal Science Division, Korea Research
Institute of Chemical Technology, Daejeon
Russian
Federation
M. V. Lomonosov Moscow State University,
Moskva
Slovakia
Institute of Experimental Oncology, Bratislava
P. J. Šafárik University, Košice
Slovak Medical University, Bratislava
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Sweden
University of Umea, Umea
Switzerland
Institute of Molecular Systems Biology, Zurich
United Arab
Emirates
United Arab Emirates University, Prof. Lorke –
Faculty of Medicine and Health Sciences –
Department of Anatomy, Al-Ain
United Kingdom
Health Protection Agency, Porton Down
University of St. Andrews, St. Andrews, Scotland
United States
Emory University, Department of Pathology,
Atlanta
Merck & Co., Inc, Whitehouse Station
MMRHVLB/CCID/CDC, Atlanta
United States
University of Washington, Seattle
Walter Reed Army Institute of Research, Silver
Spring
Wyeth, New Jersey
Participation in international projects and networks
Belgium
European Defence Agency, Brussels
Sweden
European Programme for Intervention
Epidemiology Training, European Centre
for Disease Prevention and Control, Stockholm
Switzerland
European Study Group on Nosocomial Infection,
United States
Indiana University, Bloomington, Indiana
National Institute of Health, Food and Drug
Administration, Centre of Biological Evaluation
and Research, Bethesda, Maryland
U. S. Army Medical Research Institute of
Infectious Disease, Fort Detrick
Cooperation in the field of disaster medicine
United Kingdom
Royal Centre for Defence Medicine,
Birmingham
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Other expert commissions
J. Bajgar – member of Editorial board of Archives of Hygiene and
Industrial Toxicology
R. Blanař – member of NATO RTO, Human Factors and Medicine –
Exploratory Team “Information Technology and Models for Crisis
Detection, Monitoring and Response“
R. Blanař – member of NATO (COMEDS-MMSOP)
P. Boštík – chairman of RECOOP Association Select Committee
P. Boštík – national coordinator for CBRN of Cap Tech ESM04
EDA
P. Boštík – member of Regional Cooperation for Health Science
and Technology
P. Boštík – member of Editorial board of the Open Infectious
Diseases Journal
P. Boštík – member of the Association of UICC Fellows
P. Boštík – member of the American Association of Immunologists
(AAI) R. Chlíbek – member of C.O.P.E. – Consensus on Pertussis
Booster Vaccination in Europe
P. Boštík – member of the Federation of American Societies for
Experimental Biology
V. Boštíková – International Board for the Investigation and Control
of Influenza and Other Epidemic Diseases
V. Boštíková – member of Editorial board of Journal of Clinical
Virology
R. Chlíbek – member of GPI – Global Pertussis Initiative
R. Chlíbek – member of NATO – Biological Medical Advisory
Committee
R. Chlíbek – member of NATO HFMP (Human Factor Medicine
Panel)
R. Chlíbek – member of Vaccination Advisory Board
GlaxoSmithKline Biologicals
R. Chlíbek – supervisor of CEVAG (Central European Vaccination
Awareness Group)
R. Chlíbek – member of Central and Eastern Europe Pertussis
Awareness Group
R. Chlíbek – member of C.O.P.E. – Consensus on Pertussis
Booster Vaccination in Europe
L. Jebavý – member of European Group for Blood and Marrow
Transplantation
L. Jebavý – member of Multinational Association of Supportive Care
in Cancer
L. Jebavý – member of European Study Group on Nosocomial
Infections
J. Kassa – member of NATO CBRN Medical Working Group
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J. Kassa – member of Editorial board of Journal of Medical
Chemical, Biological and Radiological Defence
J. Kassa – member of Editorial board of Challenge Medical CBRN
Defense International
L. Klein – member of Editorial board of Annals of Burns and Fire
Disasters
L. Klein – member of NATO HFMP
Z. Kročová– member of Bio EDEP Project 3
K. Kuča – member of Editorial board of Journal of Enzyme Inhibition
and Medicinal Chemistry
K. Kuča – member of Editorial board of Surgical Sciences (Scientific
Research Publishing, Inc. USA)
K. Kuča – member of Editorial board of Research in Pharmaceutical
Biotechnology (Academic Journals)
K. Kuča – member of Editorial board of ISRN Pharmaceutics
(Hindawi)
K. Kuča – member of Editorial board of World Journal of Methodology
K. Kuča – member of Editorial board of World Journal
of Translational Medicine
K. Kuča – member of Editorial board of the Open Enzyme Inhibition
Journal (Bentham)
K. Kuča – consultant of Research Network Management Working
Group; Cedar-Sinai RECOOP HST Consorcium
K. Kuča – consultant of Guidepoint Global Advisors
K. Kuča – member of Editorial board of Advances in Economics
K. Kuča – member of Editorial board of Advances in Materials
Science and Applications
K. Kuča – member of Editorial board of Biochemistry & Physiology
M. Pohanka – member of Editorial board of Journal of Biosafety
M. Pohanka – member of Editorial board of Journal of Biosensors
and Bioelectronics
M. Pohanka – member of Editorial board of Journal
of Cytoprotection and Damage Control
M. Pohanka – member of Editorial board of Journal of Bioterrorism
and Biodefense
M. Pohanka – member of Editorial board of Journal of Obesity &
Weight loss Therapy
M. Pohanka – member of Editorial board of BioMed Research
International
M. Pohanka – member of Editorial board of International Journal
of Drug Discovery
M. Pohanka – member of Editorial board of International Journal
of Health, Safety and Environments
M. Pohanka – member of Editorial board of Journal of Clinical Trials
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M. Pohanka – member of Editorial board of Microbial and
Biochemical Technology
M. Pohanka – member of Editorial board of Excellent Research
Journal of Biotechnology
R. Prymula – member of European Scientific Working Group
on Influenza
R. Prymula – member of Global Advisory Board on Pneumoccocal
Vaccines
R. Prymula – chairman of CEVAG (Central European Vaccine
Advisory Group)
R. Prymula – member of Management Board of ECDC
R. Prymula – member of Steering Committee ECDC
R. Prymula – member and secretariat of EVASG
R. Prymula – member of ISW-TBE
R. Prymula – member of SAATI
J. Smetana – member of Rotavirus Vaccination Advisory Board
GlaxoSmithKline Biologicals
H. Střítecká – member of Editorial board of Journal of Obesity &
Weight loss Therapy
H. Střítecká – member of Editorial board Journal of Food Security –
Science and Education Publishing (SciEP)
J. Stulík – member of NATO HFM TG-186
J. Stulík– member of Editorial board of Frontiers in Cellular and
Infection Microbiology
M. Špliňo – International Board for the Investigation and Control
of Influenza and Other Epidemic Diseases
M. Špliňo – European Study Group on Nosocomial Infection
R. Štětina – member of Working Group Asperillus (European Food
Safety Authority)
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SCIENTIFIC AND RESEARCH ACTIVITIES
Completed full professorships
Pazdiora Petr
Institute of Epidemiology, Faculty of Medicine, Charles University
in Pilsen
area of specialization:
Hygiene, Preventive Medicine and
Epidemiology
professor's lecture:
Concept of scientific work and treining
in the field of Hygiene, Preventive Medicine
and Epidemiology
Completed associate professorships
Růžek Daniel
Institute of Parasitology, Biology Centre, Academy of Sciences
of the Czech Republic, České Budějovice
habilitation thesis:
Medical Microbiology
Molecular aspects of epidemiology and
pathogenesis of arboviral infections
Incidence, diagnostics and taxonomy
of hemorrhagic fevers with pulmonary-renal
syndromes in the European Union countries
habilitation lecture:
Salavec Miroslav
Department of Dermatology and Venereology, Charles University
in Prague, Faculty of Medicine in Hradec Králové and Faculty Hospital
Hradec Králové
Hygiene, Preventive Medicine and
Epidemiology
Analysis of epidemiological situation
of syphilis and gonorrhoea development
in the Eastern Bohemia region
in 1981–2011
Chlamydial infections – trends in icidence,
diagnostics and treatment
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Kročová Zuzana
Institute of Molecular Pathology, Faculty of Military Health Sciences,
University of Defence, Hradec Králové
Infection Biology
Application of microbiological,
immunological and molecular biological
methods in a pathogenesis of F. tularensis
microbe
BIO DIM concept – current issue
of detection, identification and monitoring
of biological agents
Tichý Aleš
Department of Radiobiology, Faculty of Military Health Sciences,
Military Radiobiology
Reparation of radiation-induced damage
and its role in radio-sensitization of the
cancer cells
Radon and its environmental importance
Dissertation defences
Korábečný Jan
Department of Toxicology, Faculty of Military Health Sciences,
study programmes:
dissertation:
Pharmacy
Synthesis of tetrahydroacridine
acetylcholinesterase inhibitors
Fajfrová Jana
Department of Hygiene, Faculty of Military Health Sciences, University
of Defence, Hradec Králové
study programmes:
Preventive Medicine, Public Health
Protection
Enhancement of fitness and health among
career soldiers – metabolic syndrome and
non-alcoholic fatty liver disease
dissertation:
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Misík Jan
Department of Toxicology, Faculty of Military Health Sciences,
study programmes:
dissertation:
Toxicology
In vivo skin decontamination – evaluation
and optimization of new decontamination
means
Blechová Zuzana
1st Department of Infectious Diseases, 2nd Faculty of Medicine, Charles
University in Prague, University Hospital Na Bulovce
study programmes:
dissertation:
Epidemiology
Epidemiology of community infections
in children focused on pneumococci
Frank Martin
Department of Surgery, Faculty of Military Health Sciences, University
of Defence, Hradec Králové
study programmes:
dissertation:
Military Surgery
Crossover external fixator of pelvic
and acetabular fractures
Fučíková Alena
Centre of Advanced Studies, Faculty of Military Health Sciences,
study programmes:
dissertation:
Infection Biology
Use of proteomic analysis in identification
of potential biomarkers of cardiovascular
diseases
Pavliš Oto
Military Health Institute, Těchonín
study programmes:
dissertation:
Toxicology
Substances affect cholinergic
antiinflammatory pathway and their impact
on the state of the organism during
simultaneous infections
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Dresler Jiří
Central Military Health Institute, Prague
study programmes:
dissertation:
Infection Biology
Identification of new potential virulence
factors of Francisella tularensis
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REVIEW OF RESEARCH PROJECTS CARRIED OUT AT THE FMHS
THE REVIEW OF RESEARCH PROJECTS
CARRIED OUT AT THE FACULTY OF
MILITARY HEALTH SCIENCES IN 2013
THE INTERNAL GRANT AGENCY OF THE CZECH
REPUBLIC HEALTH SERVICE
Principal investigators
Kamil Kuča
(NT12062) Preparation and biological evaluation of new therapeutics against
to pesticides
Jiří Stulík
(NT13721) Targeted proteomic analysis in hypertrophic cardiomyopathy
Juraj Lenčo
(NT13599) Characterization of the diagnostic potential of native polypeptides
in amniotic fluid
Miroslav Procházka
(NT14460) Prehospital emergency care efficiency
Co-investigators
Daniel Jun
to pesticides
Miroslav Pohanka
to pesticides
Jana Žďárová Karasová
to pesticides
Alena Fučíková
(NT13721) Targeted proteomic analysis in hypertrophic cardiomyopathy
Jiří Páral
(NT13726) Parametric monitoring the quality of TME as a tool to reduce local
recurrences after surgery for rectal cancer
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THE REVIEW OF RESEARCH PROJECTS CARRIED OUT AT THE FMHS
Ladislav Jebavý
(NT11299) Quality of life measurement and its influence to overall survival
in hematopoietic stem cell transplantation in CZ
Tomáš Halajčuk
Zdeněk Hrstka
Bruno Ježek
Jan Vaněk
Jaroslav Pejchal
(NT13413) Determination of apoptosis in the bioptic samples taken
from the colon
Zdeněk Šubrt
(NT13660) Quality evaluation of multimodal treatment in patients
with colorectal liver metastatic disease: Mutlicentric study within Czech
complex oncology centres
DEFENSE THREAT REDUCTION AGENCY
Jiří Stulík
(D-CZ-10-0001) Identification of
for subunit vaccine development
novel
Francisella
tularensis
targets
THE GLAXOSMITHKLINE BIOLOGICALS CO.
Roman Chlíbek
(113077 (ZOSTER-022)) A phase III, randomized, observer-blind, placebo
controlled, multicentre, clinical vaccination trial to assess the prophylactic
gE/AS01B vaccine when administered intramuscularly on a 0, 2- month
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Roman Chlíbek
(114825, Zoster-024) An open, phase II long term extension study
to evaluate the immune responses to and safety of GSK Biologicals’
candidate herpes zoster vaccine (gE/AS01B) at Months 48, 60 and 72 postvaccination in healthy subjects aged 60 years of age and older
Roman Chlíbek
(115790 EPI-Pertussis) Epidemiological observational prospective cohort
study to evaluate the sero-prevalence of Bordetella pertussis in adults
in the Czech Republic
Roman Chlíbek
(110390 (ZOSTER-006)) A phase III, randomized, observer-blind,
placebocontrolled, multicentre, clinical vaccination trial to assess
the prophylactic efficacy, safety, and immunogenicity of GSK Biologicals´
herpes zoster gE/AS01B vaccine when administered intramuscularly on a 0,
2-month schedule in adults aged 50 years and older
Co-investigators
Jan Smetana
(113077 (ZOSTER-022)) A phase III, randomized, observer-blind, placebo
controlled, multicentre, clinical vaccination trial to assess the prophylactic
gE/AS01B vaccine when administered intramuscularly on a 0, 2- month
Jan Smetana
(115790 EPI-Pertussis) Epidemiological observational prospective cohort
study to evaluate the sero-prevalence of Bordetella pertussis in adults
in the Czech Republic
Jan Smetana
(110390 (ZOSTER-006)) A phase III, randomized, observer-blind,
placebocontrolled, multicentre, clinical vaccination trial to assess
the prophylactic efficacy, safety, and immunogenicity of GSK Biologicals´
herpes zoster gE/AS01B vaccine when administered intramuscularly on a 0,
2-month schedule in adults aged 50 years and older
Jan Smetana
(114825, Zoster-024) An open, phase II long term extension study
to evaluate the immune responses to and safety of GSK Biologicals’
candidate herpes zoster vaccine (gE/AS01B) at Months 48, 60 and 72 postvaccination in healthy subjects aged 60 years of age and older
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THE CZECH REPUBLIC MINISTRY OF INTERNAL
AFFAIRS
Zuzana Kročová
(VF20122015024) New technologies for identification and typing of biological
agents
Co-investigators
Pavel Boštík
agents
Irena Hanovcová
agents
Daniel Jun
agents
Aleš Macela
agents
GRANT AGENCY OF CHARLES UNIVERSITY
Co-investigators
Aleš Tichý
(GAUK 2013) Radio-sensibilization of MOLT-4 and SAOS-2 cell lines by
DNA repair inhibition: Phosphoproteomic analysis of irradiated cancer cells
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THE ROCHE CO.
Vanda Boštíková
(VZV) Whole varicella-zoster virus (VZV) genome sequencing of individual
Co-investigators
Jan Smetana
Pavel Boštík
Lenka Kaislerová
THE NOVARTIS
Roman Prymula
(V72P12E2, EUDRACT No 2011-004931-30) A phase 3, open label, multicenter, extension study to assess antibody persistence and response
to a third dose of Novartis meningococcal B recombinant vaccine in 4-yearold children who previously participated in study V72P12E1
Co-investigators
Roman Chlíbek
(V72P12E2, EUDRACT No 2011-004931-30) A phase 3, open label, multicenter, extension study to assess antibody persistence and response
to a third dose of Novartis meningococcal B recombinant vaccine in 4-yearold children who previously participated in study V72P12E1
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THE CZECH REPUBLIC GRANT AGENCY
Zuzana Kročová
(GAP302/11/1631) The role of B cells during natural and adaptive phase
of immune response against Francisella tularensis infection in mice
Kamil Kuča
(GAP303/11/1907) Novel inhibitors of acetylcholinesterase derived from 7MEOTA – potential Alzheimer´s disease drugs
Pavel Boštík
(GAP304/10/1161) The role of virus associated cellular proteins in Tlymphocyte dysfunction
Aleš Tichý
(GPP206/12/P338) Phosphoproteomic analysis of leukaemic cells after
irradiation
Jiří Kassa
(GAP303/12/0611) Neurobehavioral evaluation of potential Alzhemiers
disease drugs
Co-investigators
Pavel Řehulka
Vanda Boštíková
Jaroslav Pejchal
Zuzana Kročová
Jan Misík
disease drugs
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Kamil Kuča
disease drugs
Kamil Musílek
disease drugs
Jana Žďárová Karasová
disease drugs
THE MINISTRY OF EDUCATION, YOUTH
AND SPORTS
Pavel Boštík
(LH11019) Correlation of expression of KIR alleles in NK cells in GALT
and disease progression in SIV non-human primate model of AIDS
Miroslav Pohanka
(LH11023) Improvement of vaccination efficacy by cholinergic antiinflammatory pathway
Jiří Stulík
(7AMB12GR038) Proteome analysis of the interaction of host cell
with intracellular pathogen
Co-investigators
Vanda Boštíková
(LH11019) Correlation of expression of KIR alleles in NK cells in GALT and
disease progression in SIV non-human primate model of AIDS
Kamil Kuča
Pavel Boštík
th
Michal Pavlík
Martina Hrabinová
THE MINISTRY OF INDUSTRY AND TRADE
Co-investigators
Lenka Hernychová
(FR-TI1/292) Molecular diagnostics of bacterial antigens
RESEARCH AIMS
Jiří Kassa
A long-term organization development plan 1011 – Health problems
of the weapons of mass destruction
Jiří Páral
A long-term organization development plan 1011 – Clinical fields
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ARTICLES IN JOURNAL WITH IMPACT FACTOR
ARTICLES IN JOURNALS WITH IMPACT
FACTOR
1.
BABICOVÁ, A., HAVLÍNOVÁ, Z., HROCH, M., ŘEZÁŘOVÁ, M.,
PEJCHAL, J., VÁVROVÁ, J., CHLÁDEK, J. In vivo study
of radioprotective effect of NO-synthase inhibitors and acetyl-Lcarnitine. Physiological Research. 2013, 62(6), 701–710. ISSN 08628408. IF 1.531
2.
BHATTACHARJEE, AK., MUSÍLEK, K., KUČA, K. In silico
pharmacophore modeling on known pyridinium oxime reactivators
of cyclosarin (GF) inhibited AChE to aid discovery of potential, more
efficacious novel non-oxime reactivators. Current Computer-Aided Drug
Design. 2013, 9(3), 402–411. ISSN 1573-4099. IF 1.54
3.
BOŠTÍKOVÁ, V., CHLÍBEK, R., SALAVEC, M., SMETANA, J., SLEHA,
R., ŠPLIŇO, M., BOŠTÍK, P. Molecular biological and epidemiological
characteristics of varicella virus. Epidemiologie, mikrobiologie,
imunologie. 2013, 62(4), 148–152. ISSN 1210-7913. IF 0.306
4.
BUREŠ, J., KVĚTINA, J., PAVLÍK, M., KUNEŠ, M., KOPÁČOVÁ, M.,
REJCHRT, S., JUN, D., HRABINOVÁ, M., KUČA, K., TACHECÍ, I.
Impact of paraoxon followed by acetylcholinesterase reactivator HI-6
on gastric myoelectric activity in experimental pigs. Neuroendocrinology
Letters. 2013, 34(suppl. 2), 79–83. ISSN 0172-780X. IF 0.932
5.
CAHLÍKOVÁ, L., HRABINOVÁ, M., KULHÁNKOVÁ, A., BENEŠOVÁ,
N., CHLEBEK, J., JUN, D., NOVÁK, Z., MACÁKOVÁ, K., KUNEŠ, J.,
KUČA, K., OPLETAL, L. Alkaloids from chlidanthus fragrans and their
acetylcholinesterase, butyrylcholinesterase and prolyl oligopeptidase
activities. Natural Product Communications. 2013, 8(11), 1541–1544.
ISSN 1934-578X. IF 0.956
6.
ČEČKA, F., JON, B., ŠUBRT, Z., FERKO, A. Clinical and economic
consequences of pancreatic fistula after elective pancreatic resection.
Hepatobiliary & Pancreatic Diseases International. 2013, 12(5), 533–
538. ISSN 1499-3872. IF 1.259
7.
ČEČKA, F., FERKO, A., JON, B., ŠUBRT, Z., KAŠPAROVÁ, P.,
REPÁK, R. Pancreatic castleman disease treated with laparoscopic
distal pancreatectomy. Hepatobiliary & Pancreatic Diseases
International. 2013, 12(3), 332–334. ISSN 1499-3872. IF 1.259
8.
ČERVENÝ, L., STRAŠKOVÁ, A., DAŇKOVÁ, V., HÄRTLOVÁ, A.,
ČEČKOVÁ, M., ŠTAUD, F., STULÍK, J. Tetratricopeptide repeat motifs
in the world of bacterial pathogens: role in virulence mechanisms.
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ARTICLES IN JOURNALS WITH IMPACT FACTOR
Infection and Immunity. 2013, 81(3), 629–635. ISSN 0019-9567. IF
4.074
9.
ČMIELOVÁ, J., HAVELEK, R., KOHLEROVÁ, R., SOUKUP, T.,
BRUČKOVÁ, L., SUCHÁNEK, J., VÁVROVÁ, J., MOKRÝ, J.,
ŘEZÁČOVÁ, M. The effect of ATM kinase inhibition on the initial
response of human dental pulp and periodontal ligament mesenchymal
stem cells to ionizing radiation. International Journal of Radiation
Biology. 2013, 89(7), 501–511. ISSN 0955-3002. IF 1.895
10. DRTINOVÁ, L., POHANKA, M. Application of huperzine A for Alzheimer
disease treatment. Chemické listy. 2013, 107(1), 12–15. ISSN 00092770. IF 0.453
11. FABRIK, I., HÄRTLOVÁ, A., ŘEHULKA, P., STULÍK, J. Serving the new
masters – dendritic cells as hosts for stealth intracellular bacteria.
Cellular Microbiology. 2013, 15(9), 1473–1483. ISSN 1462-5814. IF
4.811
12. FIKROVÁ, P., ŠTĚTINA, R., HRNČIARIK, M., ŘEHÁČEK, V.,
HRONEK, M., ZADÁK, Z. Detection of DNA crosslinks in peripheral
lymphocytes isolated from patients treated with platinum derivates
using modified comet assay. Neoplasma. 2013, 60(4), 413–418. ISSN
0028-2685. IF 1.574
13. FRANC, V., ŘEHULKA, P., RAUS, M., STULÍK, J., NOVAK, J.,
RENFROW, MB., SEBELA, M. Elucidating heterogeneity of IgA1 hingeregion O-glycosylation by use of MALDI-TOF/TOF mass spectrometry:
Role of cysteine alkylation during sample processing. Journal
of Proteomics. 2013, 92(54), 299–312. ISSN 1874-3919. IF 4.088
14. FRANC, V., ŘEHULKA, P., MEDDA, R., PADDIGLIA, A., FLORIS, G.,
ŠEBELA, M. Analysis of the glycosylation pattern of plant copper amine
oxidases by MALDI-TOF/TOF MS coupled to a manual
chromatographic separation of glycans and glycopeptides.
Electrophoresis. 2013, 34(16), 2357–2367. ISSN 0173-0835. IF 3.261
15. HARTMANOVÁ, T., TAMBOR, V., LENČO, J., STAAB-WEIJNITZ, C.,
MASER, E., WSÓL, V. S-nitrosoglutathione covalently modifies
cysteine residues of human carbonyl reductase 1 and affects its activity.
Chemico-Biological Interactions. 2013, 202(1–3), 136–145. ISSN 00092797. IF 2.967
16. HAVELEK, R., SOUKUP, T., ČMIELOVÁ, J., SEIFRTOVÁ, M.,
SUCHÁNEK, J., VÁVROVÁ, J., MOKRÝ, J., MUTHNÁ, D.,
ŘEZÁČOVÁ, M. Ionizing radiation induces senescence and
differentiation of human dental pulp stem cells. Folia biologica (Prague).
2013, 59(5), 188–197. ISSN 0015-5500. IF 1.219
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17. HLÚBIK, J., STŘÍTECKÁ, H., HLÚBIK, P. Bioelectrical impedance
analysis or basic anthropometrical parameters for evaluating weight
loss success? Central European Journal of Medicine. 2013, 8(5), 565–
570. ISSN 1895-1058. IF 0.262
18. HORÁČEK, J., JEBAVÝ, L., VAŠATOVÁ, M., PUDIL, R., TICHÝ, M.,
JAKL, M., MALÝ, J. Glycogen phosphorylase BB as a potential marker
of cardiac toxicity in patients treated with anthracyclines for acute
leukemia. Bratislava Medical Journal-Bratislavske Lekarske Listy. 2013,
114(12), 708–710. ISSN 0006-9248. IF 0.472
19. HORÁČEK, J., VAŠATOVÁ, M., KUPSA, T., JEBAVÝ, L., ŽÁK, P. Multianalytical evaluation of serum levels of cytokines and adhesion
molecules in patients treated for acute myeloid leukemia using biochip
array technology. Biomedical Papers. 2013, 157(4), 277–279. ISSN
1213-8118. IF 0.99
20. CHLÍBEK, R., BAYAS, J., COLLINS, H., DE LA PINTA, M., LEDENT,
E., MOLS, J., HEINEMAN, T. Safety and immunogenicity of an AS01
adjuvanted varicella-zoster virus subunit candidate vaccine against
herpes zoster in adults (50 years of age). Journal of Infectious
Diseases. 2013, 12(208), 1953–1961. ISSN 0022-1899. IF 5.848
21. CHUDOBOVÁ, D., DOBEŠ, J., NEJDL, L., MAŠKOVÁ, D., RODRIGO,
M., BRANISLAV-RUTTKAY, N., KRYŠTOFOVÁ, O., KYNICKÝ, J.,
KONEČNÁ, M., POHANKA, M., HUBÁLEK, J., ZEHNÁLEK, J.,
KLEJDUS, B., KIZEK, R., ADAM, V. Oxidative stress in staphylococcus
aureus treated with silver(I) Ions revealed by spectrometric and
voltammetric assays. International Journal of Electrochemical Science.
2013, 8(4), 4422–4440. ISSN 1452-3981. IF 0
22. JAKL, M., SEVCIK, R., CERAL, J., FATOROVA, I., HORÁČEK, J.,
VOJACEK, J. Mean platelet volume and platelet count: overlooked
markers of high on-treatment platelet reactivity and worse outcome
in patients with acute coronary syndrome. Anadolu Kardiyoloji DergisiThe Anatolian Journal of Cardiology. 2013, 13(9), 4803–4804. ISSN
1302-8723. IF 0.715
23. JURÍKOVÁ, T., BALLA, S., SOCHOR, J., POHANKA, M., MLCEK, J.,
BARON, M. Flavonoid profile of saskatoon berries (Amelanchier
alnifolia nutt.) and their health promoting effects. Molecules. 2013,
18(10), 12571–12586. ISSN 1420-3049. IF 2.428
24. KACEROVSKÝ, M., TAMBOR, V., VAJRYCHOVÁ, M., LENČO, J.,
HORNYCHOVÁ, H., MUSILOVÁ, I., MENON, R. Amniotic fluid
myeloperoxidase in pregnancies complicated by preterm prelabor
rupture of membranes. Journal of Maternal-Fetal & Neonatal Medicine.
2013, 26(5), 463–468. ISSN 1476-7058. IF 1.518
th
25. KASSA, J., ŽĎÁROVÁ KARASOVÁ, J., ŠEPSOVÁ, V. A comparison
of the reactivating efficacy of a novel bispyridinium oxime K203 with
currently available oximes in VX agent-poisoned rats. Journal
of Enzyme Inhibition and Medicinal Chemistry. 2013, 28(4), 753–757.
ISSN 1475-6366. IF 1.495
26. KASSA, J., MISÍK, J., ŽĎÁROVÁ KARASOVÁ, J. Evaluation of the
potency of two novel bispyridinium oximes (K456, K458) in comparison
with the oxime K203 and trimedoxime to counteract tabun-induced
neurotoxicity in rats. Basic & Clinical Pharmacology & Toxicology. 2013,
113(3), 201–208. ISSN 1742-7835. IF 2.124
27. KASSA, J., ŠEPSOVÁ, V., MUSÍLEK, K., HOROVÁ, A. The evaluation
of the reactivating and therapeutic efficacy of three novel bispyridinium
oximes (K454, K456, K458) in comparison with the oxime K203 and
trimedoxime in tabun-poisoned rats and mice. Toxicology Mechanisms
and Methods. 2013, 23(2), 94–98. ISSN 1537-6516. IF 1.367
28. KASSA, J., ŽĎÁROVÁ KARASOVÁ, J., KREJČIOVÁ, M. Therapeutic
efficacy of a novel bispyridinium oxime K203 and commonly used
oximes (HI-6, obidoxime, trimedoxime, methoxime) in soman-poisoned
male rats and mice. Journal of Applied Biomedicine - print. 2013, 11(1),
7–13. ISSN 1214-021X. IF 0.978
29. KOMLÓOVÁ, M., HOROVÁ, A., HRABINOVÁ, M., JUN, D., DOLEŽAL,
M., VINŠOVÁ, J., KUČA, K., MUSÍLEK, K. Preparation, in vitro
evaluation
and
molecular
modelling
of
pyridinium–
quinolinium/isoquinolinium
non-symmetrical
bisquaternary
cholinesterase inhibitors. Bioorganic & Medicinal Chemistry Letters.
2013, 23(24), 6663–6666. ISSN 0960-894X. IF 2.338
30. KORÁBEČNÝ, J., JANOVEC, L., MUSÍLEK, K., ZEMEK, F., HOROVÁ,
A., NEPOVÍMOVÁ, E., DOLEŽAL, R., OPLETALOVÁ, V., HROUDOVÁ,
J., FIŠAR, Z., JUNG, Y., KUČA, K. Comparison of novel tacrine and 7MEOTA derivatives with aromatic and alicyclic residues : synthesis,
biological evaluation and docking studies. Letters in Organic Chemistry.
2013, 10(4), 291–297. ISSN 1570-1786. IF 0.667
31. KUČA, K., MUSÍLEK, K., JUN, D., ŽĎÁROVÁ KARASOVÁ, J.,
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2013, 56(6), 586–596. ISSN 0277-2116. IF 2.196
38. MIKEŠ, J., KOVAL, J., JENDŽELOVSKÝ, R., MIKEŠOVÁ, L.,
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40. MISÍK, J., JOŠT, P., PAVLÍKOVÁ, R., VODÁKOVÁ, E., CABAL, J.,
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herpesviruses. i-med. 2013, 2013(February), Art. No. P1320. ISSN
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20. BOŠTÍKOVÁ, V., SLEHA, R., KAISLEROVÁ, L. News in vaccinology.
21. BOŠTÍKOVÁ, V., SLEHA, R., KAISLEROVÁ, L. News in vaccionology.
22. BOŠTÍKOVÁ, V., SALAVEC, M., SLEHA, R., PRÁŠIL, P.,
KAISLEROVÁ, L., BOŠTÍK, P. Viral illness with blistering, diagnostics
and therapy. Referátový výběr z dermatovenerologie. 2013, 55(1), 58–
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23. ČEČKA, F., JON, B., ŠUBRT, Z., FERKO, A. Pancreatic fistula –
definition, risk factors and treatment options. Rozhledy v chirurgii. 2013,
92(2), 77–84. ISSN 0035-9351.
24. DOHNAL, V., DOHNALOVÁ, L., JUN, D., KUČA, K. Selective monitoring
of enzymatic activity of acetylcholinesterase by flow injection analysis
with mass spectrometric detection. Military Medical Science Letters.
2013, 82(3), 120–125. ISSN 0372-7025.
25. DOLÉNKOVÁ, T., HLÚBIK, P. Eating habits of adolescents and adults
as a colorectal cancer prevention. Ošetřovatelství a porodní asistence.
2013, 4(4), 670–677. ISSN 1804-2740.
26. DRTINOVÁ, L., POHANKA, M. Antioxidant markers in guinea pig
exposed to Obidoxime and HI-6 acetylcholinesterase oxime reactivators
containing oxime moiety. African Journal of Pharmacy and
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27. FAJFROVÁ, J. Non-alcoholic fatty liver disease (NAFLD) as a part
of metabolic syndrom. i-med. 2013, 3(October), Art. No.1656. ISSN
1338-4392.
28. FAJFROVÁ, J., PAVLÍK, V. Vitamins, its function and use. Medicína
pro praxi. 2013, 10(2), 81–84. ISSN 1214-8687.
29. FERKÁL, P., RŮŽIČKA, M. ACR medical support in ISAF operations.
Zpravodaj vojenské farmacie. 2013, 23(3), 11–19. ISSN 1213-8029.
30. HALAJČUK, T., PROCHÁZKA, M., JEŽEK, B., VANĚK, J. Selected cost
indicators of pre-hospital emergency care in the Czech Republic.
Journal of International Scientific Publication: Economy and Business.
2013, 7(2), 361–370. ISSN 1313-2555.
31. HLUBIK, J., HLÚBIK, P., LHOTSKÁ, L. Changes in bioimpedance
depending on conditions. Hygiena Public Health. 2013, 48(2), 185–188.
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32. HLÚBIK, J., LHOTSKÁ, L., HLÚBIK, P., STŘÍTECKÁ, H. Changes
in bioimpedance and body composition parameters depending
on measurement conditions. Hygiena Public Health. 2013, 48(2), 181–
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33. HORÁČEK, J., KUPSA, T., VAŠATOVÁ, M., JEBAVÝ, L., ŽÁK, P.
Evaluation of serum levels of multiple cytokines and adhesion molecules
in patients with newly diagnosed acute lymphoblastic leukemia using
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34. HUMLÍČEK, V. Czech Republic. Almanac of Medical Corps Worldwide.
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35. CHLÍBEK, R., SMETANA, J., BOŠTÍKOVÁ, V., ŠPLIŇO, M.,
HANOVCOVÁ, I. Vaccination schedules in Czech Republic vs. the
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36. CHLÍBEK, R. Myths and misconceptions in vaccination. První linie.
2013, 3(2), 23–27. ISSN 1804-9028.
37. CHLÍBEK, R. The risk group vaccination against pneumococcal
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38. CHLÍBEK, R. (Editor). Proceedings of Abstracts – 8th Hradec
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39. KLEIN, L. The MBC session at the 15th EBA congress in Vienna. Annals
of Burns and Fire Disasters. 2013, 26(3), 162–163. ISSN 1592-9566.
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40. KLEIN, L., GUNN, W., BOHONĚK, M., KLEIN, T. Military humanitarian
assistance to civilian populations in times of conflict – the Czech
experience. Journal of Defense Management. 2013, 2013(S3), 1–4.
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41. KLEIN, L. Important step ahead in mutual co-operation between MBC
and EBA. Annals of Burns and Fire Disasters. 2013, 26(3), 163. ISSN
1592-9566.
42. KLEIN, L. Workshop in Hradec Králové, Czech Republic, on states
of preparedness for mass-casualty situations. Military Medical Science
Letters. 2013, 82(2), 87–91. ISSN 0372-7025.
43. KLOSOVÁ, H., KLEIN, L. Surgical procedures in treatment of burns
injuries. Rozhledy v chirurgii. 2013, 92(5), 269–272. ISSN 0035-9351.
44. KONŠTACKÝ, S. Care for generations. Bulletin Sdružení praktických
lékařů ČR. 2013, 23(5), 3–5. ISSN 1212-6152.
45. KONŠTACKÝ, S. Was the program on smoking cessation a benefit
to the Army? Medical Tribune. 2013, 9(8), B5–B5. ISSN 1214-8911.
46. KONŠTACKÝ, S. Do we know how to treat cough? Bulletin Sdružení
praktických lékařů ČR. 2013, 23(1), 27–28. ISSN 1212-6152.
47. KONŠTACKÝ, S. Do you believe the National program of a complex
medical care is the right direction? Zdravotnické noviny - Lékařské listy.
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48. KONŠTACKÝ, S. Respiratory illnesses in Genenral Pracititioner's clinic.
Acta medicinae. 2013, 2(9), 74–76. ISSN 1805-398X.
49. KOSINA, P., RUMLAROVÁ, Š., PLÍŠEK, S., SMETANA, J. Clinical
manifestations of pneumococcal infections and the current prevention
options. Klinická mikrobiologie a infekční lékařství. 2013, 19(4), 120–
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50. KRAČMAROVÁ, A., BARTOŠOVÁ, L., ŽĎÁROVÁ KARASOVÁ, J.,
ZEMEK, F., BAJGAR, J. Transdermal penetration of the acetylcholinesterase reactivator HI-6 in a rat model. Military Medical Science
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51. KRAUSOVÁ, J., KOSINA, P., SMETANA, J. Vaccination in adults –
general principles. Medicína pro praxi. 2013, 10(4), 142–145. ISSN
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52. KUČA, K., MUSÍLEK, K., KORÁBEČNÝ, J., ŽĎÁROVÁ KARASOVÁ, J.,
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of oximes – antidotes against nerve agents. Journal of Environmental
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53. LORKE, DE., NURULAIN, SM., HASAN, MY., KUČA, K., PETROIANU,
GA. Five experimental bispyridinium oximes in comparison
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54. MISÍK, J. Military incapacitating agent BZ (3-quinuclidinyl benzilate) –
past, present and future. Military Medical Science Letters. 2013,
2013(82), 115–119. ISSN 0372-7025.
55. PATOČKA, J., SOUKUP, O., KUČA, K. Ladostigil – another pursuit
of a dual action cognitive enhancer. Psychiatrie. 2013, 17(2), 13–15.
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56. PAVLÍK, V., FAJFROVÁ, J. The hygienic conditions in Afghanistan.
Medical Corps International Forum. 2013, 12(1), 48–49.
57. PAVLÍK, V. Glance back at the national conference Nutrition and health.
Military Medical Science Letters. 2013, 82(3), 133–134. ISSN 03727025.
58. PAVLIŠ, O., POHANKA, M. Dividing of cholinesterase inhibitors.
59. POHANKA, M., PAVLIŠ, O. Melatonin Changes tularemia progression
in a BALB/c mouse model. African Journal of Pharmacy and
60. POHANKA, M. Butyrylcholinesterase and its using in diagnosis.
61. POHNÁN, R., ROZWADOWSKI, F., KLEIN, L., RYSKA, M. Advantages
and disadvantages of transabdominal preperitoneal approach and total
extraperitoneal approach versus open repair of inguinal hernia. Military
Medical Science Letters. 2013, 82(1), 25–31. ISSN 0372-7025.
62. POLÁK, P., KOSINA, P., BLECHOVÁ, Z., KOTEN, J., ROZSYPAL, H.,
CHLÍBEK, R., BENEŠ, J. Guidelines for treatment of patients
with impaired or lost splenic function (hyposplenism/asplenia).
63. POTUŽNÍKOVÁ, D., HELMUT, T., JUNEK, P., BEDNARČÍK, P., FIALA,
Z. Legislative intent of the noise act with respect to traffic noise control.
Transactions on Transport Sciences. 2013, 6(2), 81–88. ISSN 1802971X.
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64. PROCHÁZKA, M., HALAJČUK, T., JEŽEK, B., VANĚK, J., MAŠEK, J.
Traumatology planning in the Czech Republic in the context of new
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65. PROCHÁZKA, M., HALAJČUK, T., MAŠEK, J., JEŽEK, B., VANĚK, J.
Financing of the pre-hospital emergency care in the Czech Republic.
Journal of International Scientific Publication: Economy and Business.
2013, 7(2), 158–166. ISSN 1313-2555.
66. PRYMULA,
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67. RADOCHA, J., MAISNAR, V., ZAVŘELOVÁ, A., CERMANOVÁ, M.,
LÁNSKÁ, M., KMONÍČEK, M., JEBAVÝ, L., BLÁHA, M., MALÝ, J., ŽÁK,
P. Ffteen years of single center experience with stem cell transplantation
for multiple myeloma: a retrospective analysis. Acta Medica (Hradec
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68. RŮŽIČKA, M., STŘÍTECKÁ, H., WITT, P., HLÚBIK, P. Actual state
of affairs of the training of the medical. Military Pharmacy and Medicine.
2013, 6(1), 39–44. ISSN 1898-6498.
69. SALAVEC, M., BOSTIK, V., PRASIL, P., SMETANA, J., ŠPLIŇO, M.,
CHLÍBEK, R., LOUDA, M., BOŠTÍK, P. Opposite trends of incidence
of gonorrhea and other STIs in the eastern Bohemia during past 15
years. Military Medical Science Letters. 2013, 2013(4), 156–161. ISSN
0372-7025.
70. SLANINKA, I., KLEIN, L., HOŠEK, F., HASENÖHRLOVÁ, L., JÍŠKA, S.,
KAŠKA, M. The use of plasma rich in thrombocytes in the wound
healing – some new information and the first experience. Hojení ran.
2013, 7(2), 25–27. ISSN 1802-6400.
71. SLEHA, R., BOŠTÍKOVÁ, V., SALAVEC, M., BOŠTÍK, P., KUSAKOVA,
E., KUKLA, R., MOSIO, P., VYDRZALOVA, M., MAZUROVA, J.
Mycoplasma infections in humans. Military Medical Science Letters.
2013, 82(4), 142–148. ISSN 0372-7025.
72. SMETANA, J., KOSINA, P., BOŠTÍKOVÁ, V., CHLÍBEK, R. Vaccination
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ISSN 1802-3150.
73. SMETANA, J., KOSINA, P., BOŠTÍKOVÁ, V., HANOVCOVÁ, I.,
ŠPLIŇO, M., CHLÍBEK, R. Vaccination in high-risk groups of patients
in the GP's consulting room for adults. Medicína pro praxi. 2013, 10(5),
178–182. ISSN 1214-8687.
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74. STŘÍTECKÁ, H. Food safety and quality of foodstuff. Bio&Life. 2013,
1(11–12), 72–73. ISSN 1338-9890.
75. ŠPLIŇO, M., BOŠTÍKOVÁ, V. Ebola virus aerosol transmission from pig
to primate. Vakcinologie. 2013, 7(2), 83–84. ISSN 1802-3150.
76. ŠPLIŇO, M., BOŠTÍKOVÁ, V. Humann avian influenza A H7N9 – China.
77. ŠPLIŇO, M., BOŠTÍKOVÁ, V. Influenza – current circulation swine
viruses in the world. Vakcinologie. 2013, 7(1), 39–40. ISSN 1802-3150.
78. ŠPLIŇO, M., BOŠTÍKOVÁ, V. SEOUL hantavirus in UK – England and
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79. ŠUBRT, Z., FERKO, A., ČEČKA, F., JON, B., ÖRHALMI, J.
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80. VLČEK, V., POHANKA, M. Neurotoxic pesticides and their influence
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81. ŽĎÁROVÁ KARASOVÁ, J., KORÁBEČNÝ, J., ZEMEK, F., ŠEPSOVÁ,
V., KUČA, K. Acetylcholinesterase inhibitors used or tested
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brain barrier: in vitro study. African Journal of Pharmacy and
82. ŽĎÁROVÁ KARASOVÁ, J., JUN, D., KUČA, K. Screening of blood-brain
barrier penetration using the immobilized artificial membrane
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Military Medical Science Letters. 2013, 82(2), 55–62. ISSN 0372-7025.
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TEXTBOOKS, MONOGRAPHS, ARTICLES IN MONOGRAPHS AND PROCEEDINGS
TEXTBOOKS, MONOGRAPHS, ARTICLES
IN MONOGRAPHS AND PROCEEDINGS
1.
BAJGAR, J. Chemical warfare agents used as the content of chemical
weapons. In Biologické a chemické zbrane - pripravenosť a odpoveď.
Banská Bystrica: PRO, 2013, p. 539–599. ISBN 978-80-89057-43-6
2.
BAJGAR, J. Prophylactic possibilities in case of high risk of exposure to
nerve agents. In Disaster management. Medical prepardness, response
and homeland security. ARORA, R. (Ed.) ; ARORA, P. (Ed.) Boston:
CABI Publishing, 2013, p. 425–445. ISBN 978-1-84593-929-8
3.
FINTORA, J., VANĚK, J., JEŽEK, B. Crowd Rendering Based
on Makehuman™ Data. In Sborník příspěvků 33. konference o geometrii
a grafice. Ostrava-Poruba: Vysoká škola báňská – Technická univerzita
Ostrava, 2013, vol. 33, p. 83–96. ISBN 978-80-248-3251-7
4.
HALAJČUK, T., PROCHÁZKA, M. Economy framework ot the
emergency medical service in the Czech Republic. Sborník
recenzovaných příspěvků z mezinárodní konference Hradecké
ekonomické dny 2013, díl I. Hradec Králové: Gaudeamus, Univerzita
Hradec Králové, 2013, p. 175–181. ISBN 978-80-7435-249-2
5.
HALAJČUK, T., PROCHÁZKA, M., JEŽEK, B., VANĚK, J., ANTOŠ, K.
The last year in Disaster Medicine, what happend since last DM
conference. In Sborník příspěvků 10. ročníku celostátní konference
Medicína katastrof. Zkušenosti, příprava, praxe. Hradec Králové: ZSA,
2013, p. 31–33. ISBN 978-80-905089-2-7
6.
CHLÍBEK, R. Aluminum compounds. In Očkovanie v špeciálnych
situáciách. Praha: Mladá fronta, 2013, p. 205–216. ISBN 978-80-2042805-9
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CHLÍBEK, R. Mercury compounds. In Očkovanie v špeciálnych
situáciách. Praha: Mladá fronta, 2013, p. 216–223. ISBN 978-80-2042805-9
8.
CHLÍBEK, R. Vaccination of persons with chronic renal failure and
in those on hemodialysis. In Očkovanie v špeciálnych situáciách. Praha:
Mladá fronta, 2013, p. 153–160. ISBN 978-80-204-2805-9
9.
JANEČKA, P., PETRÁNEK, K., JEŽEK, B., VANĚK, J. Implicit surface
visualization using Raymarching. In Sborník příspěvků 33. konference
o geometrii a grafice. Ostrava-Poruba: Vysoká škola báňská –
Technická univerzita Ostrava, 2013, vol. 33, p. 133–124. ISBN 978-80248-3251-7
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10. JEŽEK, B., VANĚK, J. Heuristic label placement in image. In Sborník
příspěvků 33. konference o geometrii a grafice. Ostrava-Poruba: Vysoká
škola báňská – Technická univerzita Ostrava, 2013, vol. 33, p. 125–130.
ISBN 978-80-248-3251-7
11. KAREN, I., PRYMULA, R., CHLÍBEK, R., MANĎÁKOVÁ, Z.,
ĎURČOVIČ, J. Vaccination in the GP's consulting room, prophylaxis
of malaria and traveler's diarrhea. In Všeobecné praktické lékařství.
Praha: Galén, 2013, p. 571–599. ISBN 978-80-7262-934-3
12. KLEMENT, C., MEZENCEV, R., BAJGAR, J., MAĎAROVÁ, L., OLEÁR,
V. Selected terminology of biological and chemical weapons. In
Biologické a chemické zbrane – pripravenosť a odpoveď. Banská
Bystrica: PRO, 2013, p. 601–673. ISBN 978-80-89057-43-6
13. KLEMENT, C., MEZENCEV, R., BAJGAR, J. Biological and chemical
weapons – prepardness and response. 1. ed. Banská Bystrica: PRO,
2013. 73 p. ISBN 978-80-89057-43-6
14. KUBELKOVÁ, K., KROČOVÁ, Z., PLZÁKOVÁ, L., MACELA, A. The role
of B cells in intracellular bacterial pathogen infections. In B Cells:
Molecular Biology, Developmental Origin and Impact on the Immune
System. MONTES, RL. (Ed.) ; REYES, L. (Ed.) New York: Nova Science
Publishers – NY, 2013, p. 1–44. ISBN 978-1-62808-541-9
15. MRVEČKA, P., HUMLÍČEK, V. The field exercise Elbe 2013. Hradec
Králové: Univerzita obrany – Fakulta vojenského zdravotnictví, 2013. 9
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16. PAVLÍK, V., HLÚBIK, P., FAJFROVÁ, J. Current preventive program
in the ACR. In Sborník vědeckých prací konference Životné podmienky a
zdravie. Banská Bystrica: Slovenská epidemiologická asociácia, 2013, p.
125-127. ISBN 978-80-7159-215-0
17. PEJCHAL, J., ŠINKOROVÁ, Z., TICHÝ, A., VÁVROVÁ, J., VILASOVÁ,
Z., ZÁRYBNICKÁ, L. Biophysics for rescuers (Part 1). Vol. 369, Hradec
Králové: Univerzita obrany – Fakulta vojenského zdravotnictví, 2013. 86
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18. PETRÁNEK, K., VANĚK, J., JEŽEK, B., JANEČKA, P. Robust Image
Comparison Using Mutual Information. In Sborník příspěvků 33.
konference o geometrii a grafice. Ostrava-Poruba: Vysoká škola báňská
– Technická univerzita Ostrava, 2013, vol. 33, p. 199–204. ISBN 978-80248-3251-7
19. POHANKA, M. Overview of toxicology. Studijní texty Fakulty vojenského
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20. PROCHÁZKA, M. (Ed), JEŽEK, B. (Ed), VANĚK, J. (Ed), ANTOŠ, K.
(Ed) Proceedings of the 10th Conference on Disaster Medicine –
Experience, Preparation, Practice. Sborník příspěvků 10. ročníku
celostátní konference Medicína katastrof. Zkušenosti, příprava, praxe.
Hradec Králové: ZSA, 2013. 92 p. ISBN 978-80-905089-2-7
21. PRYMULA, R., CHLÍBEK, R. Vaccination of pregnant and lactating
women. In Očkovanie v špeciálnych situáciách. Praha: Mladá fronta,
2013, p. 160–168. ISBN 978-80-204-2805-9
22. PSUTKA, J., MALÝ, V., HUMLÍČEK, V., MRVEČKA, P. MEDEVAC
2011–2013. In Sborník příspěvků 10. ročníku celostátní konference
Medicína katastrof. Zkušenosti, příprava, praxe. Hradec Králové: ZSA,
2013, vol. 10, p. 65–66. ISBN 978–80-905089-2-7
23. VANĚK, J., JEŽEK, B. Computer graphics subjects in computer science
curricula. In Proceedings of the 10th International Conference Efficiency
and Responsibility in Education 2013. Trnava: Česká zemědělská
univerzita, 2013, vol. 10, p. 626–633. ISBN 978-80-213-2378-0
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ABSTRACTS IN JOURNAL WITH IMPACT FACTOR
ABSTRACTS IN JOURNALS WITH IMPACT
FACTOR
1.
HORÁČEK, J., KUPSA, T., VAŠATOVÁ, M., JEBAVÝ, L., JAKL, M.,
ŽÁK, P. Serum levels of multiple cytokines and adhesion molecules
in patients with newly diagnosed acute lymphoblastic leukemia and
in healthy subjects. Haematologica-The Hematology Journal. 2013,
2013(98), 500. ISSN 0390-6078. IF 5.935
2.
HORÁČEK, J., KUPSA, T., VAŠATOVÁ, M., JEBAVÝ, L., ŽÁK, P.
Evaluation of serum cytokine and adhesion molecule profile in newly
diagnosed acute leukemias using biochip array technology. Blood. 2013,
122(21), 4975. ISSN 0006-4971. IF 9.06
3.
JAKL, M., MALÝ, J., FÁTOROVÁ, I., HORÁČEK, J., PUDIL, R. High ontreatment platelet reactivity: not an isolated disorder. Haematologica-The
Hematology Journal. 2013, 98(suppl. 1), 208. ISSN 0390-6078. IF 5.935
4.
KUPSA, T., HORÁČEK, J., VAŠATOVÁ, M., JEBAVÝ, L., ŽÁK, P.
Serum profile of multiple cytokines and adhesion molecules in newly
diagnosed AML patiens differs in those who did not reach complete
remission after Antrhracyclin/Cytarabine induction therapy. Blood. 2013,
122(21), 4997. ISSN 0006-4971. IF 9.06
5.
KUPSA, T., HORÁČEK, J., VAŠATOVÁ, M., JEBAVÝ, L., ŽÁK, P.
Evaluation of serum levels of multiple cytokines and adhesion molecules
in patients treated for acute myeloid leukemia. Haematologica-The
Hematology Journal. 2013, 98(suppl. 1), 763. ISSN 0390-6078. IF 5.935
6.
MISÍK, J., KRAČMAROVÁ, A., KASSA, J. Effect of cholinesterase
inhibitors on cholinergic deficit induced by 3-quinuclidinyl benzilate
in rats performing the multiple t-maze. European Neuropsychopharmacology. 2013, 23(2), 537–538. ISSN 0924-977X. IF 4.595
7.
OSIČKOVÁ, J., KOVÁČOVÁ, V., PIKULA, J., BANĎOUCHOVÁ, H.,
KRÁL, J., SKOCHOVÁ, H., POHANKA, M., NOVOTNÝ, L. Oxidative
stress in birds: Effects of heavy metals and pharmaceuticals. Toxicology
Letters. 2013, 221(S), S111–S111. ISSN 0378-4274. IF 3.145
8.
STŘÍTECKÁ, H., HLÚBIK, P. Effects to satiation and weight reduction
of fermented milk product enriched with protein and fibre. Annals
of Nutrition and Metabolism. 2013, 63(supl.1), 436. ISSN 0250-6807. IF
1.661
9.
STŘÍTECKÁ, H., ZMRZLÁ, H., HLÚBIK, P. Is there any differences? –
Comparison of eating habits at school children with normal and excess
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weight/obesity. Annals of Nutrition and Metabolism. 2013, 63(supl.1),
721. ISSN 0250-6807. IF 1.661
10. STŘÍTECKÁ, H., HLÚBIK, P. How the Czech Army solves the problem
with obesity. Obesity Facts (print). 2013, 6(suppl. 1), 188. ISSN 16624025. IF 1.583
11. STŘÍTECKÁ, H., HLÚBIK, P., ZMRZLÁ, H. The eating habits of primary
school children – comparison of children wit normal and excess weight/
obesity. Obesity Facts (print). 2013, 6(suppl. 1), 221–222. ISSN 16624025. IF 1.583
12. ŠEPSOVÁ, V., KRŮŠEK, J., DRTINOVÁ, L., POHANKA, M., ŽĎÁROVÁ
KARASOVÁ, J. Myasthenia gravis: interaction of new acetylcholinesterase inhibitors with the nicotinic receptors. European Journal
of Neurology. 2013, 19(SI), 380. ISSN 1351-5101. IF 4.162
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ABSTRACTS
ABSTRACTS
1.
BOŠTÍKOVÁ, V., BOŠTÍK, P., PRÁŠIL, P., SALAVEC, M., SMETANA,
J., CHLÍBEK, R., KOSINA, P., PLÍŠEK, S. Genetic diversity of Varicella
zoster virus (VZV) in Europe focusing on Czech Republic – what´s now,
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ČÁP, R., SLANINKA, I., KLEIN, L. Mutilating injuries of six-year boy.
Hojení ran. 2013, 7(2), 8. ISSN 1802-6400.
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FERKO, A., ŠUBRT, Z., ČEČKA, F., JON, B. Laparoscopic vs. open
liver resection for metastatic colorectal cancer: oncological results. In:
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HORÁČEK, J., VAŠATOVÁ, M., PUDIL, R., JAKL, M., ŽÁK, P.,
JEBAVÝ, L. Multiple biomarkers in the detection of cardiotoxicity during
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hematologické dny s mezinárodní účastí – sborník abstrakt.
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HORÁČEK, J., JEBAVÝ, L., VAŠATOVÁ, M., TICHÝ, M., ŽÁK, P.
Assessment of cardiotoxicity induced by conventional and high-dose
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0372-7025.
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HORÁČEK, J., VAŠATOVÁ, M., PUDIL, R., ŽÁK, P., JEBAVÝ, L.
The use of cardiac biomarkers in the detection of cardiotoxicity
associated with stem cell transplantation for hematological
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ISSN 0372-7025.
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HORÁČEK, J., JEBAVÝ, L., VAŠATOVÁ, M., ŽÁK, P., TICHÝ, M.,
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HORÁČEK, J., KUPSA, T., VAŠATOVÁ, M., ŽÁK, P., JEBAVÝ, L.
Serum cytokine and adhesion molecule levels in patients with acute
lymphoblastic leukemia and in healthy subjects. In: Proceedings and
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10. HORÁČEK, J., CERMANOVÁ, M., ZAVŘELOVÁ, A., LÁNSKÁ, M.,
JEBAVÝ, L., ŽÁK, P. Treatment of adult acute lymphoblastic leukemia
according to GMALL 07/2003 protocol – single center experience. In: 27.
Olomoucké hematologické dny s mezinárodní účastí – sborník abstrakt.
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11. HORÁČEK, J., VAŠATOVÁ, M., KUPSA, T., ŽÁK, P., JEBAVÝ, L.
Evaluation of serum cytokine and adhesion molecule concentrations
in patients treated for acute myeloid leukemia. In: 27. Olomoucké
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Evaluation of serum levels of adhesion molecules by biochip array
technology in acute myeloid leukemia patients. In: Biochimica Clinica.
Milano: BIOMEDIA. 2013, p. 200.
13. HORÁČEK, J., VAŠATOVÁ, M., KUPSA, T., JEBAVÝ, L., ŽÁK, P.
Serum levels of multiple cytokines and adhesion molecules in patients
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2013, p. 315–316.
14. HRABINOVÁ, M., CAHLÍKOVÁ, L., CHLEBEK, J., BENEŠOVÁ, N.,
KUČA, K., OPLETATL, L., JUN, D. Novel prolyl oligopeptidase inhibitors
from the group of isoquinoline alkaloids – possible candidates
for Alzheimer disease drug discovery. Military Medical Science Letters.
2013, 82(suppl. 1), 9–10. ISSN 0372-7025.
15. CHLÍBEK, R. News in a multi approach to vaccination of adults. In:
Sborník abstrakt 9. hradeckých vakcinologických dnů. Praha: Česká
vakcinologická společnost. 2013, p. 72–72. ISBN 978-80-260-4939-5.
16. CHLÍBEK, R. Current vaccination schedules of European countries
in comparison with the Czech calendar. In: Sborník abstrakt 9.
hradeckých vakcinologických dnů. Praha: Česká vakcinologická
společnost. 2013, p. 41–42. ISBN 978-80-260-4939-5.
17. CHLÍBEK, R. The procedure for checks protection and possible
vaccination against HBV. Vakcinologie. 2013, 7(1), 24–25. ISSN 18023150.
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ABSTRACTS
18. CHLÍBEK, R., MACHAČ, J., SMETANA, J., FABIÁNOVÁ, K.,
ZAVADILOVÁ, J., DÍTĚ, P., GÁL, P., NÁPLAVA, P., LŽIČAŘOVÁ, D.
The results of seroprevalence studies of pertussis in the Czech Republic
– influence vaccination strategy. In: Sborník abstrakt 9. hradeckých
vakcinologických dnů. Praha: Česká vakcinologická společnost. 2013, p.
66–66. ISBN 978-80-260-4939-5.
19. CHLÍBEK, R., SMETANA, J., FABIÁNOVÁ, K., ZAVADILOVÁ, J., DÍTĚ,
P., GÁL, P., LŽÍČAŘOVÁ, D. Seroprevalence of Bordetella pertussis
in adults in the Czech Republic. In: Český kongres o infekčních
nemocech – sborník abstrakt. Brno: Společnost infekčního lékařství.
2013, p. 17–17. ISBN 978-80-260-4768-1.
20. CHLÍBEK, R. Priorities for vaccination in 2013 from the perspective
of GPs. Medicína pro praxi. 2013, 10(8), 10–10. ISSN 1214-8687.
21. CHLÍBEK, R. News vaccination in adults. Vakcinologie. 2013, 7(1), 24–
24. ISSN 1802-3150.
22. CHLÍBEK, R. Trends in adult vaccination and the introduction of new
vaccines. Pediatria / Pediatrics. 2013, 8(1), 15–16. ISSN 1336-863X.
23. CHLÍBEK, R. Multiconsensunal view in vaccination. In: Wonca 2013.
Prague: Wonca. 2013, p. 23.
24. CHLÍBEK, R. Non-standard situations in vaccination practice GP`s. In:
Sborník abstrakt 9. hradeckých vakcinologických dnů. Praha: Česká
25. JUN, D., KŘENKOVÁ, Z., MUSÍLEK, K., KUČA, K. Bioscavengers –
efficient antidotes for poisoning by nerve agents and organophosphorus
pesticides. In: Military Medical Science Letters. Hradec Králové:
University of Defence, Faculty of Military Health Sciences. 2013, p. 14.
26. KRAČMAROVÁ, A., ŽĎÁROVÁ KARASOVÁ, J., ZEMEK, F., BAJGAR,
J. In vitro testing of HI-6 skin permeation. Military Medical Science
Letters. 2013, 82(suppl. 1), 17–17. ISSN 0372-7025.
27. KUPSA, T., HORÁČEK, J., VAŠATOVÁ, M., JEBAVÝ, L., ŽÁK, P.
Evaluation of serum concentrations of multiple cytokines and adhesion
molecules in patients with newly diagnosed acute myeloid leukemia. In:
27. Olomoucké hematologické dny s mezinárodní účastí – sborník
abstrakt. Olomouc: UP Olomouc. 2013, p. 58. ISBN 978-80-244-3480-3.
28. KUPSA, T., HORÁČEK, J. Evaluation of serum levels of multiple
cytokines and adhesion molecules in patients treated for acute myeloid
leukemia. In: Abstracts book of the 10th International Medical
Postgraduate Conference. 2013, p. 49–51. ISBN 978-80-260-5300-2.
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29. LOCHMAN, P., LEŠKO, M., PÁRAL, J. Alocally advanced primary
gastric lymphoma invading spleen, pancreas and transverse colon. In:
10th International Gastric Cancer Congress. Verona: International
Gastric Cancer Association. 2013, p. 217–217.
30. MAREK, J., SOUKUP, O., CABAL, J., KUČA, K. Development of novel
quaternary detergents as part of decontamination and disinfection
means. Zjazd Chemikov. 2013, 9100. ISSN 1336-7242.
31. MISÍK, J. Military incapacitating agent BZ (3-quinuclidinyl benzilate)
in behavioral research. Military Medical Science Letters. 2013, 82(suppl.
1), 21–22. ISSN 0372-7025.
32. PAVLÍK, V., HLÚBIK, P., FAJFROVÁ, J., NAVRÁTIL, P. Prevention
of obesity in the Army of the Czech Republic. In: Sborník abstrakt:
Prevence obezity v AČR. Teplice: Zdravotní ústav Ústí nad labem. 2013,
p. 25. ISBN 978-80-905541-1-5.
33. POHANKA, M., ADAM, V., KIZEK, R. Electrochemical assay
of butyrylcholinesterase in biological samples. In: 13. Pracovní setkání
fyzikálních chemiků a elektrochemiků – sborník abstrakt. 2013, p. 11–
11.
34. POHANKA, M., ŠTĚTINA, R., SVOBODOVÁ, H., RUTTKAY-NEDECKÝ,
B., JÍLKOVÁ, M., SOCHOR, J., SOBOTKA, J., ADAM, V., KIZEK, R.
Sulfur mustard causes oxidative stress and depletion of antioxidants
in organs of wistar rats. In: 37. Brněnské onkologické dny a 27.
Konference pro nelékařské zdravotnické pracovníky. 2013, p. 156–156.
ISBN 978-80-904596-9-4.
35. POHANKA, M. Modulation of immunization via cholinergic nervous
system using HI-6. In: Journal Bacteriology and Infectious Diseases.
2013, p. 45–45.
36. PRYMULA, R., CHLÍBEK, R., KOSINA, P., SMETANA, J. Pneumococcal
disease and new recommendation for adult immunization in the Czech
Republic. In: Abstracts of the 2nd International Conference
on Controversies in Vaccination in Adults (CoVAC). 2013, p. A-2.
37. RUTTKAY-NEDECKÝ, B., HYNEK, D., ŽUREK, M., MAŠKOVÁ, D.,
NEJDL, L., POHANKA, M., ADAM, V., KIZEK, R. Use of electrochemical
methods for evaluation of critical health condition. In: 13. Pracovní
setkání fyzikálních chemiků a elektrochemiků – sborník abstrakt. 2013,
p. 114–114. ISBN 978-80-7375-757-1.
38. SMETANA, J., CHLÍBEK, R., GÁL, P., DÍTĚ, P., BOŠTÍKOVÁ, V.,
TRTÍLKOVÁ, M. Knowledge of the voluntary adult vaccination.
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39. SMETANA, J., CHLÍBEK, R., BOŠTÍKOVÁ, V. Vaccination against
tetanus in adulthood, new recommendations. In: Sborník abstrakt 9.
hradeckých vakcinologických dnů. Praha: Česká vakcinologická
společnost. 2013, p. 80–80. ISBN 978-80-260-4939-5.
40. SMETANA, J., CHLÍBEK, R., BOŠTÍKOVÁ, V. Present vaccination
against tetanus. In: Sborník abstrakt 9. hradeckých vakcinologických
dnů. Praha: České vakcinologická společnost ČLS JEP. 2013, p. 53–53.
ISBN 978-80-260-4939-5.
41. SOUKUP, O., KORÁBEČNÝ, J., ŠPILOVSKÁ, K., MUSÍLEK, K., JUN,
D., MISÍK, J., ŽĎÁROVÁ KARASOVÁ, J., KUČA, K. Hybrids of AChE
inhibitor and memantine derivatives as candidates for Alzheimer´s
disease treatment. In: Neuroscience 2013. 2013, p. 100.
42. SOUKUP, O., JUN, D., TOBIN, G., KUČA, K. Non-reactivating
properties of oxime reactivators. In: Korean Chemical Society Meeting.
2013, p. 100.
43. ŠPILOVSKÁ, K., KORÁBEČNÝ, J., MUSÍLEK, K., HOROVÁ, A.,
ŠEPSOVÁ, V., DRTINOVÁ, L., KUČA, K. Synthesis and in vitro
screening
of
7-methoxytacrine-adamantylamine
heterodimers
as potential cholinesterase inhibitors in Alzheimer's disease therapy. In:
14th International Symposium on Cholinergic Mechanisms. 2013, p. 2.
BENEK, O., DRTINOVÁ, L., ŠEPSOVÁ, V., KASSA, J., NEPOVIMOVÁ,
E., KUČA, K. 7-methoxytacrine-adamantylamine heterodimers
as potential cholinesterase inhibitors in AD treatment – synthesis,
biological evaluation and molecular docking. In: The 11th International
Conference on Alzheimer's and Parkinson's disease. 2013, p. 1.
BENEK, O., KUČA, K. Synthesis and biological testing of 7methoxytacrine-adamantylamine
heterodimers
as
potential
cholinesterase inhibitors in Alzheimer's disease. In: Sborník příspěvků
55. česko-slovenské psychofarmakologické konference. Praha: Česká
neuropsychofarmakologická společnost. 2013, p. 2.
46. ŠPLIŇO, M., BOŠTÍKOVÁ, V. Measles – recurring problem in Europe.
In: Sborník abstrakt 9. hradeckých vakcinologických dnů. Praha: Česká
47. ŠUBRT, Z., FERKO, A., ČEČKA, F., JON, B. Rare primary tumors –
case reports. In: 40. česko-slovenský chirurgický kongres s mezinárodní
účastí a 6. kongres chirurgie jater, žlučových cest a pankreatu – sborník
abstrakt. Plzeň: EUROVERLAG. 2013, p. 67. ISBN 978-80-7177-977-3.
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ABSTRACTS
48. ŠUBRT, Z., FERKO, A., ČEČKA, F., JON, B. Surgical treatment of liver
metastases of colorectal cancer: analysis of predictive factors. In: 40.
česko-slovenský chirurgický kongres s mezinárodní účastí a 6. kongres
chirurgie jater, žlučových cest a pankreatu – sborník abstrakt. Plzeň:
EUROVERLAG. 2013, p. 60. ISBN 978-80-7177-977-3.
49. ŠUBRT, Z., FERKO, A., ČEČKA, F., JON, B. Laparoscopic vs. open
liver resection for metastatic colorectal cancer: oncological result. In: 40.
česko-slovenský chirurgický kongres s mezinárodní účastí a 6. kongres
chirurgie jater, žlučových cest a pankreatu – sborník abstrakt. Plzeň:
EUROVERLAG. 2013, p. 67. ISBN 978-80-7177-977-3.
50. ŽĎÁROVÁ KARASOVÁ, J., PAVLÍK, M., CHLÁDEK, J., JUN, D., KUČA,
K. Oxime HI-6 salts (dichloride and dimethansulphonate): Hyaluronidase
effect on biovaibility after i. m. application. Military Medical Science
Letters. 2013, 82(suppl. 1), 39. ISSN 0372-7025.
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PRESENTATIONS AND POSTERS
1.
BALONOVÁ, L. Current knowledge of the Francisella tularensis
glycobiology. Velká Úpa: Výroční zasedání ÚMP a CPS. 28.11.2013–
29.11.2013.
2.
BALONOVÁ, L. Protein glycosylation in Francisella tularensis:
identification of a novel glycosylated lipoprotein. Hradec Králové: 3.
neformální proteomické setkání. 21.11.2013–22.11.2013.
3.
BENEK, O., ŠPILOVSKÁ, K., KORÁBEČNÝ, J., KUČA, K., GUNNMOORE, F., MUSÍLEK, K. Inhibitors of ABAD-Aβ interaction as potential
AD treatment. Florence, Italy: 11th International Conference Alzheimer’s
and Parkinson’s Diseases. 06.03.2013–10.03.2013. /POSTER/
4.
BOŠTÍK, P. CBRN defense and potential new threats from "common"
technologies. Rio de Janeiro, Brasil: CBRN Threat Defense Seminar.
28.11.2013–30.11.2013.
5.
BOŠTÍK, P., BOŠTÍKOVÁ, V. Identification and strain surveillance of
clinical isolates of varicella-zoster virus (VZV) in Europe using molecular
epidemiology. Wuhan, China: BIT`s 3rd Annual World Congress of
Microbes. 30.07.2013–01.08.2013.
6.
BOŠTÍKOVÁ, V., BOŠTÍK, P., PRÁŠIL, P., SALAVEC, M., SMETANA,
J., CHLÍBEK, R., KOSINA, P., PLÍŠEK, S. Genetic diversity of Varicella
zoster virus (VZV) in Europe focusing on Czech Republic – What´s now,
and what´s next. Cape Town, RSA: 8th World Congress of the Society
for Pediatric Infectious Diseas. 19.11.2013–22.11.2013. /POSTER/
7.
BOŠTÍKOVÁ, V., BOŠTÍK, P., PRÁŠIL, P., PLÍŠEK, S., SMETANA, J.,
CHLÍBEK, R. Breakthrough varicella-zoster infection after immunization,
presenting as chickenpox in child with cystic fibrosis (CF). Cape Town,
RSA: 8th World Congress of the Society for Pediatric Infectious
Diseases. 19.11.2013–22.11.2013. /POSTER/
8.
ČÁP, R., ŠKOLOUDÍK, L. Surgical treatment of malignant tumors
of the skin on head and neck. Hradec Králové: ORL kongres.
24.05.2013–24.05.2013.
9.
ČÁP, R. Non-adherent covering for the vacuum treatment of wounds.
Bedřichov u Liberce: Safetac Club. 04.10.2013–05.10.2013.
10. ČÁP, R., KLEIN, L. Paralysis of the facial nerve from the perspective
of a plastic surgeon. Hradec Králové: Schůze České společnosti
otorinolaryngologie
a
chirurgie
hlavy
a
krku
ČLS
JEP
Královéhradeckého a Pardubického regionu. 17.10.2013–17.10.2013.
th
11. DAŇKOVÁ, V., BALONOVÁ, L., STULÍK, J. The ABC transporter is
required for host cell adhesion, glycosylation, and virulence
in the bacterium Francisella tularensis. Urgup, Turkey: International
Symposium on Francisella tularensis and Tularemia. 19.06.2013–
22.06.2013. /POSTER/
12. DOHNALOVÁ, L., DOHNAL, V., STŘÍTECKÁ, H. Comparison BIO
versus nonBIO – current findings. Praha: Výživa, potraviny a zdraví – 5.
studentská konference. 12.06.2013–12.06.2013.
13. DRESLER, J., RIEHM, J., PAJER, P., HUBÁLEK, M., KLIMENTOVÁ, J.,
FUČÍKOVÁ, A., MATĚJKOVÁ, J., SCHOLZ, H., PÍŠA, L. Detection and
differentiation of BoNT by mass spectrometry. Munich, Germany:
Medical Biodefense Conference 2013. 22.10.2013–25.10.2013.
14. DRTINOVÁ, L., DOBEŠ, P., POHANKA, M. Low molecular weight
precursor applicable for Alzheimer disease drugs synthesis (AChE and
BChE inhibition, BACE inhibition, antioxidant properties and in silico
modulation). Hradec Králové: 18th Interdisciplinary Czech-Slovak
Toxicology Conference (TOXCON 2013). 19.06.2013–21.06.2013.
/POSTER/
15. DRTINOVÁ, L., POHANKA, M., KRAČMAROVÁ, A., ŠEPSOVÁ, V.
Evaluation of chemical percursors for their ability to inhibit enzyme
acetylcholinesterae.
Lázně
Jeseník:
55.
česko-slovenská
psychofarmakologická konference. 04.01.2013–08.01.2013. /POSTER/
16. DRTINOVÁ, L., POHANKA, M., ŠPILOVSKÁ, K., KORÁBEČNÝ, J.,
ŠEPSOVÁ, V., KRAČMAROVÁ, A., KUČA, K., KASSA, J.,
NEPOVIMOVÁ, E., MISÍK, J. Comparison of potencial ability to inhibit
beta-secretase with standard drugs for AD treatment. Florence, Italy:
11th international konference on Alzheimer´s and Parkinson´s diseases.
06.03.2013–10.03.2013. /POSTER/
17. FABIÁNOVÁ, K., CHLÍBEK, R., SMETANA, J., ZAVADILOVÁ, J., DÍTĚ,
P., GÁL, P., LŽIČAŘOVÁ, D., MACHAČ, J. Seroprevalence
of antibodies Bordetella pertussis in adults in the Czech Republic.
Olomouc: Kongres klinické mikrobiologie, infekčních nemocí a
epidemiologie. 17.10.2013–19.10.2013.
18. FABRIK, I., LINK, M., HÄRTLOVÁ, A., DAŇKOVÁ, V., ŘEHULKA, P.,
STULÍK, J. SILAC labeling reveals extensive GM-CSF-dependent
arginine metabolism in primary bone marrow-derived dendritic cells.
Hradec Králové: 3. Česká konference pro hmotnostní spektroemtrii.
16.10.2013–18.10.2013. /POSTER/
th
19. FABRIK, I. Mass spectrometry: MaxQuant (data-processing software
for Orbitrap). Hradec Králové: Interní výukový seminář laboratorních
metod. 12.02.2013–26.02.2013.
20. FABRIK, I. GM-CSF-dependent arginine metabolism affects SILAC
labeling in primary dendritic cells. Hradec Králové: 7. fakultní konference
studentů doktorských programů. 01.10.2013–01.10.2013.
21. FAJFROVÁ, J. Therapy and prevention of obesity. Těchonín: Vojenská
odborná příprava. 27.05.2013–27.05.2013.
22. FAJFROVÁ, J., PAVLÍK, V., BEDNARČÍK, P., HLÚBIK, P. Limitation of
BMI for diagnosing overweight in Czech Army. Hradec Králové:
Obezitologie a bariatrie 2013. 17.10.2013–19.10.2013. /POSTER/
23. FAJFROVÁ, J. Nonalcoholic fatty liver disease. Praha: Školení lékařů
spádu IV. 27.11.2013–27.11.2013.
24. FAJFROVÁ, J. Military hygiene and epidemiological service – activity in
the branch of Ministry of Defence. Hradec Králové: Vstupní odborná
příprava příslušníků zdravotnické a veterinární služby AČR. 13.11.2013–
14.11.2013.
25. FAJFROVÁ, J., PAVLÍK, V., BEDNARČÍK, P., HLÚBIK, P.
Recommendation for diagnosing obesity in Czech Army. Kúpele Nový
Smokovec, Slovakia: 21. vedecko-odborná konferencia s medzinárodnou účasťou Životné podmienky a zdravie. 23.09.2013–25.09.2013.
/POSTER/
26. FAJFROVÁ, J. Improvement of fitness and health of military
professionals – metabolic syndrom and nonalcoholic fatty liver disease.
Hradec Králové: Vědecká rada FVZ. 18.09.2013–18.09.2013.
27. FAJFROVÁ, J. Therapy and prevention of obesity. Chrudim: Vojenská
odborná příprava. 30.08.2013–30.08.2013.
28. FAJFROVÁ, J., PAVLÍK, V., BEDNARČÍK, P., HLÚBIK, P. Limitation
of BMI for diagnosing overweight in Czech Army. Hradec Králové: 13.
konference odborné Společnosti vojenských lékařů, farmaceutů
a veterinárních lékařů ČLS JEP. 24.10.2013–24.10.2013. /POSTER/
29. FERKO, A., ŠUBRT, Z., ČEČKA, F., JON, B. Laparoscopic vs. open
liver resection for metastatic colorectal cancer: oncological results.
Ostrava: 10. Ostravské dny miniinvazivní chirurgie. 07.11.2013–
08.11.2013.
30. FERKO, A., ŠUBRT, Z. Two case reports: bile duct injury during
cholecystectomy with an unusually complicated course. Are we able
th
to learn? Karlovy Vary: 5. kongres
společnosti. 07.11.2013–09.11.2013.
České
gastroenterologické
31. FINTORA, J., VANĚK, J., JEŽEK, B. Crowd rendering based
on Makehuman™ data. Horní Lomná: Sborník příspěvků 33. konference
o geometrii a grafice. 09.09.2013–12.09.2013.
32. FIŠER, V., PROCHÁZKA, M. Trauma planning on the level of regional
government and emergfency medical service. Hradec Králové: Seminář
Centra andragogiky. 17.01.2013–17.01.2013.
33. FUČÍKOVÁ, A., DRESLER, J., ŘEHULKOVÁ, H., ZÍDKOVÁ, L., LENČO,
J., STULÍK, J., PUDIL, R. Potential plasma markers of hypertrophic
cardiomyopathy – targeted proteomic analysis of soluble fibronectin.
Yokohama, Japan: HUPO 2013. 12.09.2013–19.09.2013. /POSTER/
34. FUČÍKOVÁ, A., DRESLER, J., JUN, D., KROČOVÁ, Z., MACELA, A.,
SCHMIDT, M., STULÍK, J. Targeted proteomic analysis of ricin. Munich,
Germany: Medical Biodefence Conference. 22.10.2013–25.10.2013.
/POSTER/
35. GRÖGER, T. First aid in the field. Hradec Králové: 13. konference
odborné Společnosti vojenských lékařů, farmaceutů a veterinárních
lékařů ČLS JEP. 24.10.2013–24.10.2013. /POSTER/
36. HALAJČUK, T., PROCHÁZKA, M. Economy framework of the emergency medical service in the Czech Republic. Hradec Králové: Hradecké
ekonomické dny. 19.02.2013–20.02.2013.
37. HALAJČUK, T., PROCHÁZKA, M. Selected cost indicators of prehospital emergency care in the Czech Republic. Sunny Beach, Bulgaria:
International Scientific Symposium Economy & Business. 01.09.2013–
06.09.2013.
38. HALAJČUK, T., PROCHÁZKA, M. Trauma plan analysis. Hradec
Králové: 10. ročník celostátní konference Medicína katastrof.
Zkušenosti, příprava, praxe. 28.11.2013–29.11.2013.
39. HALAJČUK, T., PROCHÁZKA, M. Economy frame of pre-hospital
emergency care financing in the Czech Republic. Hradec Králové:
Ekonomická efektivita v PNP? 27.11.2013–27.11.2013.
40. HAMULÁKOVÁ, S., ŠPILOVSKÁ, K., HRABINOVÁ, M., JANOVEC, L.,
KUČA, K., IMRICH, J. Syntesis and biological efficacy tacrine-coumarine
analoges as potential Alzheimer´s drugs. Tatranské Matliare, Slovakia:
65. Zjazd chemikov. 09.09.2013–13.09.2013.
th
41. HAVEL, F., NOVOTNÝ, F., JELÍNEK, M., PROŠKA, J., KUČA, K.,
MUSÍLEK, K. Optimalization of optothermal properties of gold nanorods.
Brno: NANOCON 2013. 16.10.2013–18.10.2013. /POSTER/
42. HLÚBIK, J., HLÚBIK, P., STŘÍTECKÁ, H. Use BIA analysis or basic
anthropometrical parametres to evaluate the success of weight loss.
Hradec Králové: Obezitologie a bariatrie 2013. 17.10.2013–19.10.2013.
/POSTER/
43. HLÚBIK, J., HLÚBIK, P., LHOTSKÁ, L. Changes in bioimpendance
depending on conditions. Biała Podlaska, Poland: Higiena żywności i
żywienia podstawą zdrowia. 03.09.2013–06.09.2013.
44. HLÚBIK, J., LHOTSKÁ, L., STŘÍTECKÁ, H., HLÚBIK, P. Changes
in bioimpedance and body composition parameters depending
on measurements conditions. Biała Podlaska, Poland: Higiena żywności
i żywienia podstawą zdrowia. 03.09.2013–06.09.2013.
45. HLÚBIK, P., HLÚBIK, J., STŘÍTECKÁ, H. Modified polysaccharides –
possibilities and limitations in influencing metabolic disorders. Špindlerův
Mlýn: 17. kongres o ateroskleróze. 05.12.2013–07.12.2013.
46. HORÁČEK, J., KUPSA, T., VAŠATOVÁ, M., ŽÁK, P., JEBAVÝ, L.
Assessment of serum cytokine and adhesion molecule levels in patients
with acute lymphoblastic leukemia using biochip array technology.
Hradec Králové: 13. konference odborné Společnosti vojenských lékařů,
farmaceutů a veterinárních lékařů ČLS JEP. 24.10.2013–24.10.2013.
/POSTER/
47. HORÁČEK, J., KUPSA, T., VAŠATOVÁ, M., JEBAVÝ, L., ŽÁK, P.
Serum concentrations of cytokines and adhesion molecules in patients
with newly diagnosed acute lymphoblastic leukemia. Olomouc: 27.
Olomoucké hematologické dny s mezinárodní účastí. 12.05.2013–
14.05.2013. /POSTER/
Evaluation of serum levels of adhesion molecules by biochip array
technology in acute myeloid leukemia patients. Milan, Italy: 20th IFCCEFLM European Congress of Clinical Chemistry and Laboratory
Medicine (EuroMedLab). 19.05.2013–23.05.2013. /POSTER/
49. HORÁČEK, J., JEBAVÝ, L., VAŠATOVÁ, M., TICHÝ, M., ŽÁK, P.
Assessment of cardiotoxicity induced by conventional and high-dose
chemotherapy for acute leukemia with multiple biomarkers of cardiac
injury. Hradec Králové: 18th Interdisciplinary Czech-Slovak Toxicology
Conference (TOXCON 2013). 19.06.2013–21.06.2013. /POSTER/
50. HORÁČEK, J., CERMANOVÁ, M., ZAVŘELOVÁ, A., LÁNSKÁ, M.,
JEBAVÝ, L., ŽÁK, P. Treatment of adult acute lymphoblastic leukemia
th
according to GMALL 07/2003 protocol – single center experience.
Olomouc: 27. Olomoucké hematologické dny s mezinárodní účastí.
12.05.2013–14.05.2013.
51. HORÁČEK, J., ŽÁK, P., KUPSA, T., JAKL, M., BRNDIAR, M., JEBAVÝ,
L. Acute lymphoblastic leukemia – innovations in diagnostics
and treatment. Brno: 59. konference vojenských internistů. 17.10.2013–
18.10.2013.
52. HORÁČEK, J., VAŠATOVÁ, M., PUDIL, R., ŽÁK, P., JEBAVÝ, L.
The use of cardiac biomarkers in the detection of cardiotoxicity
associated with stem cell transplantation for hematological
malignancies. Hradec Králové: 18th Interdisciplinary Czech-Slovak
/POSTER/
53. HORÁČEK, J., VAŠATOVÁ, M., PUDIL, R., TICHÝ, M., JAKL, M.,
JEBAVÝ, L. Cardiac biomarkers and assessment of cardiotoxicity
in patients treated for acute leukemia. Hradec Králové: 13. konference
Odborné společnosti vojenských lékařů, farmaceutů a veterinárních
54. HORÁČEK, J., JEBAVÝ, L., VAŠATOVÁ, M., ŽÁK, P., TICHÝ, M.,
MALÝ, J. Multiple biomarkers in the detection of cardiotoxicity induced
by conventional and high-dose chemotherapy for acute leukemia.
Istanbul, Turkey: 4th International Congress on Leukemia Lymphoma
Myeloma. 22.05.2013–25.05.2013. /POSTER/
55. HORÁČEK, J. Acute leukamias on ASH 2012. Hradec Králové:
Hematologický seminář 4. interní hematologické kliniky FN Hradec
Králové. 23.01.2013–23.01.2013.
56. HORÁČEK, J. Treatment outcomes of acute lymphoblastic leukemia
in University Hospital Hradec Kralove. Hradec Králové: Hematologický
seminář 4. interní hematologické kliniky FN Hradec Králové.
20.02.2013–20.02.2013.
57. HORÁČEK, J., KUPSA, T., VAŠATOVÁ, M., ŽÁK, P., JEBAVÝ, L.
Serum cytokine and adhesion molecule levels in patients with acute
lymphoblastic leukemia and in healthy subjects. Istanbul, Turkey: 4th
International Congress on Leukemia Lymphoma Myeloma. 22.05.2013–
25.05.2013. /POSTER/
Evaluation of serum cytokine and adhesion molecule concentrations
in patients treated for acute myeloid leukemia. Brno: 37. Brněnské
onkologické dny a 27. Konference pro nelékařské zdravotnické
pracovníky. 18.04.2013–19.04.2013.
th
59. HORÁČEK, J., VAŠATOVÁ, M., KUPSA, T., JEBAVÝ, L., ŽÁK, P.
Serum levels of multiple cytokines and adhesion molecules in patients
treated for acute myeloid leukemia. Istanbul, Turkey: 4th International
Congress on Leukemia Lymphoma Myeloma. 22.05.2013–25.05.2013.
/POSTER/
60. HORÁČEK, J., VAŠATOVÁ, M., PUDIL, R., JAKL, M., ŽÁK, P.,
JEBAVÝ, L. Multiple biomarkers in the detection of cardiotoxicity during
stem cell transplantation for hematological malignancies. Istanbul,
Turkey: 4th International Congress on Leukemia Lymphoma Myeloma.
22.05.2013–25.05.2013. /POSTER/
61. HOSTÝNKOVÁ, V. Identification of immunogenic epitope of microbe
Francisella tularensis. Velká Úpa: Výroční zasedání ÚMP a CPS za rok
2013. 28.11.2013–29.11.2013.
62. HOSTÝNKOVÁ, V., STRAŠKOVÁ, A., LINK, M., STULÍK, J.
Establishment of in vitro infection of mouse BMDC with F. tularensis
strain LVS. Brno: The Student Scientific Conference on Biotechnology
and Biomedicine 2013. 10.04.2013–12.04.2013. /POSTER/
63. HRSTKA, Z. Burn out syndrome by healthcare workers during
peacekeeping missions. Praha: 5. kongres anestezie a intenzivní péče
za mimořádných podmínek. 17.10.2013–18.10.2013.
64. HRSTKA, Z. Critical incident stress management. Hradec Králové: 19.
královéhradecké
ošetřovatelské
dny.
12.09.2013–13.09.2013.
/POSTER/
65. HRSTKA, Z. Differences of perception between social workers by
gender. Hradec Králové: Hradecké dny sociální práce. 27.09.2013–
28.09.2013.
66. HRSTKA, Z. Differences in perception quality of life females versus
males. Hradec Králové: 7. konference všeobecných sester a radiologických asistentů. 15.03.2013–15.03.2013.
67. HRSTKA, Z. Ethics and communication. Hradec Králové: Regionální
seminář onkologů. 09.10.2013–09.10.2013.
68. HRSTKA, Z. Psychology and coping with cancer. Hradec Králové:
Regionální seminář onkologů. 11.04.2013–11.04.2013.
69. HRSTKA, Z. Communication with patients.
praktických lékařů. 23.01.2013–23.01.2013.
Tábor:
Konference
70. HRSTKA, Z. Pain control by psychological means. Hradec Králové: 19.
královéhradecké
ošetřovatelské
dny.
12.09.2013–13.09.2013.
/POSTER/
th
71. HRSTKA, Z. Psychological aspects of dying and death. Hradec Králové:
Regionální seminář onkologů. 14.01.2013–14.01.2013.
72. HRSTKA, Z. Health psychology. Praha: Vzdělávací seminář lékařů.
04.02.2013–04.02.2013.
73. HRSTKA, Z., SLOVÁČEK, L. The support system of health care
professionals exposed to excess stress load. Hradec Králové:
Vzdělávací programy pro zdravotnické profesionály. 23.04.2013–
23.04.2013.
74. HRSTKA, Z. Psychology of health and illness. Rychnov nad Kněžnou:
Seminář k problémům dětí s handicapem. 12.11.2013–12.11.2013.
75. HRSTKA, Z. Aggression. Brno: 4. psychoonkologické sympozium.
11.09.2013–11.09.2013.
76. HRSTKA, Z. Experiencing the quality of life – women versus men.
Praha: 5. kongres anestezie a intenzivní péče za mimořádných
podmínek. 17.10.2013–18.10.2013.
77. HUMLÍČEK, V. Medical service organization and control under the terms
of physicians professional education. Praha: Konference hlavních
odborníků vojenské zdravotnické služby. 26.11.2013–26.11.2013.
78. HUMLÍČEK, V. Professional education of physicians in the area
of military medical service control. Hradec Králové: 13. konference
odborné Společnosti vojenských lékařů, farmaceutů a veterinárních
lékařů ČLS JEP. 24.10.2013–24.10.2013.
79. CHLÍBEK, R. Vaccination of adult patients and recommendations
for vaccination against pneumococcal infection. Praha: Astma a
CHOPN. 23.01.2013–23.01.2013.
80. CHLÍBEK, R. Prophylaxis and treatment of bio accident victims. Vyškov:
JCBRN Defence Centre of Excellence – Crisis Management after CBRN
Incident/Pilot Course. 11.11.2013–15.11.2013.
81. CHLÍBEK, R. Vaccination guidelines, vaccination calendar 2013.
Jihlava: Očkování z celoživotního pohledu v ordinaci praktického lékaře.
05.06.2013–05.06.2013.
82. CHLÍBEK, R. Multiconsensual view in vaccination. Praha: Wonca 2013.
25.06.2013–29.06.2013.
83. CHLÍBEK, R. Tick-borne encephalitis – prevention. Pardubice: Český
rozhlas Pardubice – pořad Máme hosty. 23.04.2013–23.04.2013.
th
84. CHLÍBEK, R. A first responders perspective to bio-incidents. Vyškov:
JCBRN Defence Centre of Excellence – Crisis Management after CBRN
for vaccination against pneumococcal infection. Zlín: Astma a CHOPN.
07.01.2013–07.01.2013.
for vaccination against pneumococcal infection. Ústí nad Labem: Astma
a CHOPN. 10.01.2013–10.01.2013.
87. CHLÍBEK, R. Adult vaccination and recommendation for pneumococcal
vacination. Ostrava: Úskalí praktické medicíny. 15.05.2013–15.05.2013.
88. CHLÍBEK, R. Vaccination guidelines, vaccination calendar 2013. Ústí
nad Labem: Očkování z celoživotního pohledu v ordinaci praktického
lékaře. 17.09.2013–17.09.2013.
89. CHLÍBEK, R. Optional vaccination from a vaccinologist´s point of view.
České Budějovice: Celorepublikový cyklus vzdělávacích seminárů pro
praktické lékaře pro děti a dorost na téma Očkování. 14.11.2013–
14.11.2013.
90. CHLÍBEK, R., SMETANA, J., ŠOŠOVIČKOVÁ, R. Analysis of epidemic
cholera in Haiti – a lesson for the present. Hradec Králové: 10. ročník
celostátní konference Medicína katastrof. Zkušenosti, příprava, praxe.
28.11.2013–29.11.2013.
91. CHLÍBEK, R. Trends in adult vaccination and the introduction of new
vaccines. Štrbské Pleso, Slovakia: 4. Slovenský vakcinologický kongres.
17.01.2013–19.01.2013.
92. CHLÍBEK, R. Interdisciplinary approach – vaccination in high-risk
patients. Praha: 7. jarní interaktivní konference SVL ČLS JEP.
12.04.2013–14.04.2013.
Ostrava: Celorepublikový cyklus vzdělávacích seminárů pro praktické
lékaře pro děti a dorost na téma Očkování. 12.09.2013–12.09.2013.
P., GÁL, P., LŽÍČAŘOVÁ, D., BOŠTÍKOVÁ, V., ŠPLIŇO, M.
The seroepidemiology of Bordetella pertussis in the Czech Republic.
Cape Town, RSA: 8th World Congress of the Society for Pediatric
Infectious Diseases. 19.11.2013–22.11.2013. /POSTER/
th
Plzeň: Celorepublikový cyklus vzdělávacích seminárů pro praktické
lékaře pro děti a dorost na téma Očkování. 10.09.2013–10.09.2013.
for vaccination against pneumococcal infection. Ostrava: Astma a
CHOPN. 22.01.2013–22.01.2013.
97. CHLÍBEK, R. Vaccination and public health. Bratislava, Slovakia: 10.
slovenský pediatrický kongres. 25.04.2013–27.04.2013.
98. CHLÍBEK, R. Difficulties in practical medicine. Ostrava: Seminář
praktických lékařů. 15.05.2013–15.05.2013.
P., GÁL, P., LŽÍČAŘOVÁ, D. Seroprevalence of Bordetella pertussis
in adults in the Czech Republic. Brno: Český kongres o infekčních
nemocech. 25.09.2013–27.09.2013.
100. CHLÍBEK, R. Vaccination guidelines, vaccination calendar 2013. Praha:
Očkování z celoživotního pohledu v ordinaci praktického lékaře.
11.09.2013–11.09.2013.
101. CHLÍBEK, R. Vaccination guidelines, vaccination calendar 2013. Brno:
Očkování z celoživotního pohledu v ordinaci praktického lékaře.
24.09.2013–24.09.2013.
102. CHLÍBEK, R. Adult vaccination and recommendation for pneumococcal
vaccination. Brno: Úskalí praktické medicíny. 06.06.2013–06.06.2013.
103. CHLÍBEK, R. Vaccination guidelines, vaccination calendar 2013. Hradec
Králové: Očkování z celoživotního pohledu v ordinaci praktického lékaře.
10.06.2013–10.06.2013.
104. CHLÍBEK, R., SMETANA, J. Multidisciplinary approaches to vaccination.
Praha: 20th World Conference Family Medicine – Care for Generations,
Wonca 2013. 25.06.2013–29.06.2013.
105. CHLÍBEK, R., MACHAČ, J., SMETANA, J., FABIÁNOVÁ, K.,
ZAVADILOVÁ, J., DÍTĚ, P., GÁL, P., NÁPLAVA, P., LŽÍČAŘOVÁ, D.
The results of seroprevalence studies of pertussis in the Czech Republic
– influence vaccination strategy. Hradec Králové: 9. Hradecké
vakcinologické dny. 03.10.2013–05.10.2013. /POSTER/
106. CHLÍBEK, R. News vaccination in 2013. Ústí nad Labem: Konference
Co nového v očkování v roce 2013 – pro všeobecné sestry ordinací
lékařů pro děti a dorost. 07.12.2013–07.12.2013.
th
107. CHLÍBEK, R. Update on pertussis. Belgrade, Serbia: Central and
Eastern Europe Pertussis Awareness Group. 30.01.2013–31.01.2013.
108. CHLÍBEK, R. The vaccination schedule for adults. Praha: Očkování
v dospělosti. 15.04.2013–15.04.2013.
109. CHLÍBEK, R. Vaccinate? Olomouc: 48th International
of Science Documentary Films. 16.04.2013–21.04.2013.
Festival
110. CHLÍBEK, R., SMETANA, J., BOŠTÍKOVÁ, V., ŠPLIŇO, M. Adult
vaccination – recommendation. Poprad, Slovakia: 17. Slovensko-Český
kongres o infekčních chorobách. 13.06.2013–15.06.2013.
111. CHLÍBEK, R. Priorities for vaccination in 2013 from the perspective
of GPs. Olomouc: 11. kongres praktických lékařů a sester. 25.04.2013–
26.04.2013.
112. JAKL, M., MALÝ, J., FÁTOROVÁ, I., HORÁČEK, J., PUDIL, R. High ontreatment platelet reactivity: not an isolated disorder. Stockholm,
Sweden: 18th Congress of EHA. 13.06.2013–16.06.2013. /POSTER/
113. JAKL, M., FÁTOROVÁ, I., HORÁČEK, J. The failure of antiplatelet
therapy in the context of other disorders of haemostasis. Brno: 59.
konference vojenských internistů. 17.10.2013–18.10.2013.
114. JAKL, M., BIS, J., HORÁČEK, J. Evalution of the effect of balloon aortic
valvuloplasty. Hradec Králové: 13. konference odborné Společnosti
vojenských lékařů, farmaceutů a veterinárních lékařů ČLS JEP.
24.10.2013–24.10.2013. /POSTER/
115. JANEČKA, P., PETRÁNEK, K., JEŽEK, B., VANĚK, J. Implicit surface
visualization using Raymarching. Horní Lomná: 33. konference
o geometrii a grafice. 09.09.2013–12.09.2013.
116. JANOČKOVÁ, J., GULASOVA, Z., PLSIKOVA, J., MUSÍLEK, K., KUČA,
K., MIKES, J., CULKA, L., FEDOROCKO, P., KOZURKOVA, M.
Biological activity of cholinesterase modulators and their interactions
with DNA. Hradec Králové: 18th Interdisciplinary Czech-Slovak
/POSTER/
117. JAREŠOVÁ, L. A historical view of burn treatment. Hradec Králové: 10.
ročník celostátní konference Medicína katastrof. Zkušenosti, příprava,
praxe. 28.11.2013–29.11.2013. /POSTER/
118. JAREŠOVÁ, L. Operation of the Czechoslovak field hospital in Korea
during the period 1952–1954. Brno: Po stopách zdraví a nemoci člověka
a zvířat. 24.09.2013–25.09.2013. /POSTER/
th
119. JAREŠOVÁ, L. Czechoslovak medical help in Korea during the period
1952–1954. Praha: Pracovní den sester. 16.05.2013–16.05.2013.
120. JAREŠOVÁ, L. Czechoslovak military medical help in war conflicts
during the 20th century – The Korean War. Praha: 5. kongres Anestézie
a intenzivní péče za mimořádných podmínek. 17.10.2013–18.10.2013.
121. JAREŠOVÁ, L. A historical view of burn treatment. Hradec Králové: 2.
celostátní Královéhradecký kongres perioperačních sester a chirurgických intenzivistů. 25.09.2013–26.09.2013.
122. JAREŠOVÁ, L. Women active participation in army medical corps during
the World War II. Hradec Králové: 13. konference odborné Společnosti
24.10.2013–24.10.2013.
123. JAREŠOVÁ, L. A historical view of burn treatment. Praha: 5. kongres
Anestézie a intenzivní péče za mimořádných podmínek. 17.10.2013–
18.10.2013. /POSTER/
124. JAREŠOVÁ, L. Operation of the Czechoslovak field hospital in Korea
during the period 1952 – 1954. Praha: 5. kongres Anestézie a intenzivní
péče za mimořádných podmínek. 17.10.2012–18.10.2013. /POSTER/
125. JEBAVÝ, L., KAČEROVSKÝ, J., ZAVORAL, M., BRABEC, T.,
VYHNÁNEK, M., HALATA, P., HŘÍBEK, M. Summary of Activities
in the field of internal medicine in the Medical Service of the ACR
for the year 2012. Brno: 59. konference vojenských internistů.
17.10.2013–18.10.2013.
126. JEBAVÝ, L. Military Internal Medicine, view main expert of medical
Service ACR. Hradec Králové: 13. konference Odborné společnosti
24.10.2013–24.10.2013.
127. JEŽEK, B., VANĚK, J., PROCHÁZKA, M. Major incident simulation.
Pardubice: SW nástroje na řešení úloh racionalizace, objektivizace
a optimalizace (nejen) pokrytí území veřejnými obslužnými systémy.
28.11.2013–29.11.2013.
128. JEŽEK, B., VANĚK, J., PETRÁNEK, K. Space in computer graphics.
Hradec Králové: Letní škola FIM UHK. 13.05.2013–16.05.2013.
129. JEŽEK, B., VANĚK, J., PROCHÁZKA, M., HALAJČUK, T., PETRÁNEK,
K. Simulation and GIS in major incident preparation. Praha: Konference
GIS Esri v ČR. 13.11.2013–14.11.2013. /POSTER/
th
130. JEŽEK, B., VANĚK, J. Heuristic label placement in image. Horní Lomná:
Sborník příspěvků 33. konference o geometrii a grafice. 09.09.2013–
12.09.2013.
131. JOŠT, P., FIKROVÁ, P., JÍLKOVÁ, M. Detection of alkylation DNA
damage induced sulphur mustard and 2- chlorethyl ethyl sulphide using
comet assay. Porto, Portugal: The 10th International Comet Assay
Workshop. 18.09.2013–20.09.2013. /POSTER/
132. JUN, D., KŘENKOVÁ, Z., MUSÍLEK, K., KUČA, K. In vitro oximeassisted reactivation of human butyrylcholinesterase – development
of potential prophylaxis for nerve agent intoxications. Cavtat, Croatia:
CSCM – World Congress on CBRN Science & Consequence
Management. 14.04.2013–19.04.2013.
133. KASSA, J., ŽĎÁROVÁ KARASOVÁ, J., ŠTĚTINA, R., BAJGAR, J.
The benefit of combinations of acetylcholinesterase reactivators
for the antidotal treatment of poisonings with cyclosarin. Munich,
Germany: 14th International Medical Chemical Defence Conference.
24.04.2013–25.04.2013. /POSTER/
134. KASSA, J., MISÍK, J., ŽĎÁROVÁ KARASOVÁ, J. A comparison
of neuroprotective efficacy of a novel oxime K203 with obidoxime
and the oxime HI-6 in sarin-poisoned rats. Lázně Jeseník: 55. československá psychofarmakologická konference. 04.01.2013–08.01.2013.
/POSTER/
135. KASSA, J., ŠEPSOVÁ, V., TŮMOVÁ, M., HOROVÁ, A., MUSÍLEK, K.
The evaluation of the reactivating and therapeutic efficacy of two newly
developed oximes K361 and K378 in comparison with the oxime K203
and trimedoxime in tabun-poisoned rats and mice. Olomouc: 63. ČeskoSlovenské farmakologické dny. 11.09.2013–13.09.2013. /POSTER/
136. KASSA, J. Antidotes against chemical warfare agents in the Czech
Army – presence and future. Brno: 66th CIOR Congress and the 67th
CIOMR Congress. 30.07.2013–02.08.2013.
137. KASSA, J., KORÁBEČNÝ, J., ŠEPSOVÁ, V., TŮMOVÁ, M., HOROVÁ,
A., MUSÍLEK, K. The development of modulators of cholinesterases and
the evaluation of their reactivating or inhibiting efficacy by the in vitro
and in vivo methods. Hradec Králové: 13. konference odborné
Společnosti vojenských lékařů, farmaceutů a veterinárních lékařů ČLS
JEP. 24.10.2013–24.10.2013. /POSTER/
138. KASSA, J., ŠEPSOVÁ, V., MISÍK, J., ŽĎÁROVÁ KARASOVÁ, J.,
KUČA, K., MUSÍLEK, K., HOROVÁ, A., BAJGAR, J. The reactivating,
therapeutic and neuroprotective efficacy of two newly developed oximes
(K456, K458) in rats and mice poisoned with tabun – a comparison
th
with the oxime K203 and trimedoxime. Hradec Králové: 18th
Interdisciplinary Czech-Slovak Toxicology Conference (TOXCON 2013).
19.06.2013–21.06.2013.
139. KASSA, J., MISÍK, J. Cognitive deficit induced by cholinergic antagonist
3-quinuclidinyl benzilate – potential pharmacological model of Alzheimer
disease. Florence: AD/PD™ 2013: The 11th International Conference
on Alzheimer’s and Parkinson’s Diseases. 06.03.2013–10.03.2013.
/POSTER/
140. KLEIN, L., HAVEL, E., ŠMEJKAL, K., ZAJÍČEK, R. Combination
of mechanical and burns injuries. Hanoi, Vietnam: The 9th Asia – Pacific
Burn Congress. 02.04.2013–05.04.2013.
141. KLEIN, L. Procedures for management of delivery of humanitarian
assistance to civilian populations in times of conflict – the Czech
experience. Vienna, Austria: 15th European Burns Association
Congress. 28.08.2013–31.08.2013.
142. KLIMENTOVÁ, J. Ultrafiltration and concentration of protein samples by
Millipore Stirred Ultrafiltration Cell. Hradec Králové: Interní výukový
seminář laboratorních metod. 19.02.2013–19.02.2013.
143. KLIMENTOVÁ, J. Analysis of protein complexes by Blue Native
Polyacrylamide Gel Electrophoresis (BN-PAGE). Hradec Králové: Interní
výukový seminář laboratorních metod. 19.02.2013–19.02.2013.
144. KLIMENTOVÁ, J. Outer membrane vesicles of F. tularensis. Velká Úpa:
Výroční zasedání ÚMP a CPS. 28.11.2013–29.11.2013.
145. KORÁBEČNÝ, J., MUSÍLEK, K., BABKOVÁ, K., SOUKUP, O.,
HOROVÁ, A., ŠPILOVSKÁ, K., ŠEPSOVÁ, V., ŽĎÁROVÁ KARASOVÁ,
J., KASSA, J., JUN, D., KUČA, K. Centrally and peripherally active Ache
inhibitors – prophylaxis against nerve agents. Cavtat, Croatia: CSCM –
World Congress on CBRNe Science & Consequence Management.
14.04.2013–19.04.2013.
146. KOSINA, P., SMETANA, J. Vaccination in questions and answers –
parent view. Brno: Vzdělávací seminář SPLDD na téma 2+1 netradiční
pohledy na očkování a péči o pokožku. 30.10.2013–30.10.2013.
147. KOSINA, P., SMETANA, J. Questions and answers on the practice
pediatrician. České Budějovice: Vzdělávací seminář pro PLDD na téma
Očkování. 04.11.2013–04.11.2013.
pediatrician. Hradec Králové: Celorepublikový cyklus vzdělávacích
seminářů pro praktické lékaře pro děti a dorost na téma Očkování.
18.06.2013–18.06.2013.
th
parent view. Ostrava: Vzdělávací seminář SPLDD na téma 2+1
netradiční pohledy na očkování a péči o pokožku. 12.11.2013–
12.11.2013.
pediatrician. Brno: Vzdělávací seminář pro PLDD na téma Očkování.
23.05.2013–23.05.2013.
pediatrician. Ostrava: Vzdělávací seminář pro PLDD na téma Očkování.
12.09.2013–12.09.2013.
parent view. Plzeň: Vzdělávací seminář SPLDD na téma 2+1 netradiční
153. KRAČMAROVÁ, A., POHANKA, M. Cognitivum tacrine influences
oxidative balance of organism. Lázně Jeseník: 55. česko-slovenská
psychofarmakologická konference. 04.01.2013–08.01.2013. /POSTER/
154. KRAČMAROVÁ, A., POHANKA, M., PIKULA, J., BANĎOUCHOVÁ, H.,
DRTINOVÁ, L., ŠEPSOVÁ, V., ŠPILOVSKÁ, K. Effect of tacrine
on oxidative stress and plasma biochemistry in laboratory Guinea pig
model. Florence, Italy: AD/PD™ 2013: The 11th International
Conference on Alzheimer’s and Parkinson’s Diseases. 06.03.2013–
10.03.2013. /POSTER/
155. KRAČMAROVÁ, A., MISÍK, J., KASSA, J., POHANKA, M.
Immunomodulating effect of selected neurodrugs on murine
macrophage cell line j774.2. Barcelona, Spain: 26th ECNP Congress.
05.10.2013–10.10.2013. /POSTER/
156. KRAČMAROVÁ, A., ŽĎÁROVÁ KARASOVÁ, J., ZEMEK, F., BAJGAR,
J. In vitro testing of HI-6 skin permeation. Hradec Králové: 18th
Interdisciplinary Czech-Slovak Toxicology Conference (TOXCON 2013).
19.06.2013–21.06.2013. /POSTER/
157. KRAČMAROVÁ, A., PAVLIŠ, O., DRTINOVÁ, L., POHANKA, M.
Immunomodulating effect of selected drugs due to cholinergic
antiinflammatory pathway. Brno: 2. Květinův den. 23.05.2013–
23.05.2013.
158. KROČOVÁ, Z., KUBELKOVÁ, K., PLZÁKOVÁ, L., ZÁRYBNICKÁ, L.,
ŠINKOROVÁ, Z., MACELA, A. The B cells and innate immune response
against intracellular bacterial pathogen Francisella tularensis. Mikulov:
International Conference Analytical Cytometry VII. 21.09.2013–
24.09.2013. /POSTER/
th
ŠINKOROVÁ, Z., MACELA, A. The role of B cells in the early stages
of immune response against intracellular bacterial pathogen Francisella
tularensis. Pultusk, Poland: B Cells from Bedside to Bench and Back
Again. 02.09.2013–07.09.2013. /POSTER/
ŠINKOROVÁ, Z., MACELA, A. B cells participate on the early stages
of immune response against intracellular bacterial pathogen Francisella
tularensis. Milan, Italy: 15th International Congress of Immunology.
22.08.2013–27.08.2013.
161. KUBELKOVÁ, K. PathScan antibody arrays and its application. Hradec
Králové: Nové pohledy na účinek ionizujícího záření na živý organismus.
11.12.2013–11.12.2013.
162. KUBELKOVÁ, K. Effect of the ionizing radiation on the course
of infectious diseases. Malá Úpa: Výroční zasedání ÚMP a CPS.
28.11.2013–29.11.2013.
163. KUBELKOVÁ, K., ORLÍKOVÁ, A., KROČOVÁ, Z., MACELA, A.,
PEJCHAL, J., BOŠTÍK, P. Humoral immunity involving antibodies and B
cells as an outstaning helper during experimental Francisella tularensis
infection. Matrahaza, Hungary: Impulse 2013 – EFIS-EJI Symposium.
31.08.2013–04.09.2013. /POSTER/
164. KUČA, K., SOUKUP, O. Development of skin decontamination means
based on micellar origin. Daejon, South Korea: Seminar of Korean
Research Institute of Chemical Technology. 15.10.2013–18.01.2013.
165. KUČA, K. From the synthesis of new molecule to its practical
application. Hradec Králové: 18th Interdisciplinary Czech-Slovak
166. KUČA, K., MUSÍLEK, K., JUN, D., ŽĎÁROVÁ KARASOVÁ, J., KUNEŠ,
M., SOUKUP, O., KORÁBEČNÝ, J., ŠEPSOVÁ, V., HRABINOVÁ, M.
Novel acetylcholinesterase reactivators – antidotes against nerve
agents. Singapore: Conference on Pharmacology and Drug
Development. 09.12.2013–11.12.2013. /POSTER/
167. KUČA, K., SOUKUP, O. Development of novel nerve agent antidotes
in Czech Republic – prophylaxis and treatment. Daejon, South Korea:
Seminar of Korean Research Institute of Chemical Technology.
13.10.2013–18.10.2013.
168. KUČA, K., JUN, D., MUSÍLEK, K. Development of novel cholinesterase
reactivators – Czech approach. Paris, France: European Workshop
on Reactivators of Inhibited Cholinesterases. 06.11.2013–07.11.2013.
th
169. KUNEŠ, M., ŽĎÁROVÁ KARASOVÁ, J., ZEMEK, F., KVĚTINA, J.,
PAVLÍK, M., JUN, D., BUREŠ, J., KUČA, K. Detection
of acetylcholinesterase
reacti-vators
in
biological
samples:
pharmacokinetics of oximes hi-6 and K027 in pig. Velké Karlovice:
Syntéza a analýza léčiv. 02.09.2013–05.09.2013. /POSTER/
170. KUNEŠ, M., MUSÍLEK, K., JUN, D., ŽĎÁROVÁ KARASOVÁ, J.,
KASSA, J., SOUKUP, O., HRABINOVÁ, M., KUČA, K.
Acetylcholinesterase reactivators and surfactants with a promising
application potential. Cavtat, Croatia: CSCM – World Congress on
CBRNe Science & Consequence Management. 14.04.2013–19.04.2013.
Evaluation of serum concentrations of multiple cytokines and adhesion
molecules in patients with newly diagnosed acute myeloid leukemia.
Olomouc: 27. Olomoucké hematologické dny s mezinárodní účastí.
11.05.2013–14.05.2013. /POSTER/
172. KUPSA,
T.,
HORÁČEK,
J.,
JEBAVÝ,
L.
Transplantation
of hematopoietic stem cell – very general. Brno: 59. konference
vojenských internistů. 17.10.2013–18.10.2013.
173. KUPSA, T. MDS/MPS and AML on EHA 2013. Hradec Králové:
Hematologický seminář 4. interní hematologické kliniky FN Hradec
Králové. 26.06.2013–26.06.2013.
174. KUPSA, T., HORÁČEK, J. Analysis of selected prognostic factors
in patients with acute myeloid leukemia – the influence of cytokines and
adhesion molecules. Hradec Králové: 7. konference PGS studentů.
01.10.2013–01.10.2013.
175. KUPSA, T., HORÁČEK, J. Evaluation of serum levels of multiple
cytokines and adhesion molecules in patients treated for acute myeloid
leukemia. Hradec Králové: 10. mezinárodní konference PGS studentů.
21.11.2013–22.11.2013.
176. KUPSA, T., VOGLOVÁ, J. Patient J. J., 1953. Deštné v Orlických
horách: Regionální hematologické setkání. 04.10.2013–04.10.2013.
Serum concentrations of selected cytokines and adhesion molecules
in patients treated for acute myeloid leukemia. Hradec Králové: 13.
konference Odborné společnosti lékařů, farmaceutů a veterinárních
178. LENČO, J. Advanced analyses of proteins using mass spectrometry.
Hradec Králové: Letní škola LFHK – 2013: Vybrané metodické přístupy
v biomedicínském výzkumu a jejich aplikace. 10.06.2013–11.06.2013.
th
179. LENČO, J., TAMBOR, V., VAJRYCHOVÁ, M., KACEROVSKÝ, M.
PPROM: diagnostic potential of proteomic markers cathelicidin and
myeloperoxidase in infection and inflammation. Praha: 13. Konference
fetální medicíny ČLS JEP. 11.01.2013–20.12.2013.
180. LINK, M. Current technology status and apllications on nLC-Q-Orbi.
Velká Úpa: Výroční zasedání ÚMP a CPS. 28.11.2013–29.11.2013.
181. MAČEK, N., RADIC, Z., TAYLOR, P., KUČA, K., KOVARIK, Z. Structural
analogs of the HI-6 oxime are the most potent reactivators of the somaninhibited AChE mutant that resists ageing. Munich, Germany: 14th
International Medical Chemical Defence Conference. 24.04.2013–
25.04.2013. /POSTER/
182. MACHAČ, J., CHLÍBEK, R., FABIÁNOVÁ, K., PLÍŠEK, S. Reported and
actual incidence of pertussis – access to vaccination strategy. Olomouc:
Kongres klinické mikrobiologie, infekčních nemocí a epidemiologie.
17.10.2013–19.10.2013. /POSTER/
183. MALIŠOVÁ, Z., PAVLÍK, V. Coldness and woddcutters hob. Nový
Smokovec, Slovakia: Životné podmienky a zdravie. 23.09.2013–
25.09.2013. /POSTER/
184. MAREK, J., SOUKUP, O., CABAL, J., KUČA, K. Development of novel
quaternary detergents as part of decontamination and disinfection
means. Tatranské Matliare, Slovakia: Zjazd Chemikov. 09.09.2013–
13.10.2013. /POSTER/
185. MAREK, J., JUN, D., KUČA, K., BARTOŠOVÁ, L. Preparation of new
cationic surfactants and their disinfection efficiency evaluation. Krems,
Austria: 4th International Congress Nanotechnology, Medicine and
Biology. 13.03.2013–15.03.2013.
186. MATOUŠEK, R. Military acute care, BATLS philosophy. Praha: IPVZ.
14.05.2013–14.05.2013.
187. MATOUŠEK, R. BATLS in the Army of the Czech Republic. Hradec
Králové: 13. konference odborné Společnosti vojenských lékařů,
farmaceutů a veterinárních lékařů ČLS JEP. 24.10.2013–24.10.2013.
/POSTER/
188. MISÍK, J. Effects of anticholinergic agents on learning and memory
in the laboratory rat. Hradec Králové: 13. konference odborné
Společnosti vojenských lékařů, farmaceutů a veterinárních lékařů ČLS
JEP. 24.10.2013–24.10.2013. /POSTER/
189. MISÍK, J., SOUKUP, O., MUSÍLEK, K., KUČA, K., KASSA, J.
Therapeutic effect of cholinesterase inhibitors rivastigmine, donepezil
and tacrine on cognitive deficit induced by 3-quinuclidinyl benzilate
th
in rats performing passive avoidance test. San Diego,
Neuroscience 2013. 08.11.2013–13.12.2013. /POSTER/
USA:
190. MISÍK, J., KASSA, J., ŠEPSOVÁ, V., KORÁBEČNÝ, J., DRTINOVÁ, L.
Therapeutic effect of tacrine, rivastigmine and donepezil on cognitive
deficit induced by 3-quinuclidinyl benzilate in rats performing the passive
avoidance task. Florence, Italy: AD/PD™ 2013: The 11th International
10.03.2013. /POSTER/
191. MISÍK, J. Military incapacitating agent BZ (3-quinuclidinyl benzilate)
in behavioral research. Hradec Králové: 18th Interdisciplinary CzechSlovak Toxicology Conference (TOXCON 2013). 19.06.2013–
21.06.2013.
192. MISÍK, J., KASSA, J. Impact of cholinergic antagonist 3-guinuclidinyl
benzilate on spatial learning and memory in the laboratory rat. Lázně
Jeseník: 55. česko-slovenská psychofarmakologická konference.
04.01.2013–08.01.2013. /POSTER/
193. MISÍK, J., KRAČMAROVÁ, A., KASSA, J. Effect of cholinesterase
inhibitors on cholinergic deficit induced by 3-quinuclidinyl benzilate
in rats performing the multiple T-maze. Barcelona, Spain: 26th ECNP
Congress. 05.10.2013–10.10.2013. /POSTER/
194. MUSÍLEK, K., KAŠPÁREK, A., HOROVÁ, A., HERMAN, D.,
KŘENKOVÁ, Z., JUN, D., KUČA, K. Monooxime bisquaternary
cholinesterase reactivators with 3-oxapent-1,5-diyl linker – preparation
and in vitro screening study. Munich, Germany: 14th Medical Chemical
Defence Conference. 24.04.2013–25.04.2013. /POSTER/
195. MUSÍLEK, K., KAŠPÁREK, A., KUNEŠ, M., HOROVÁ, A., HERMAN, D.,
KŘENKOVÁ, Z., JUN, D., KUČA, K. Oxime acetylcholinesterase
reactivators with 3-oxapent-1,5-diyl linker – synthesis and in vitro
evaluation. Tatranské Matliare, Slovakia: 65. Zjazd chemikov.
09.09.2013–13.09.2013. /POSTER/
196. MUSÍLEK, K., KUNEŠ, M., JUN, D., ŽĎÁROVÁ KARASOVÁ, J.,
ŠEPSOVÁ, V., KORÁBEČNÝ, J., HRABINOVÁ, M., KUČA, K.
Cholinesterase inhibitors as prophylaxis against nerve agents. Velké
Karlovice: Syntéza a analýza léčiv. 02.09.2013–05.09.2013. /POSTER/
197. ONDRÁČEK, K., OSIČKOVÁ, J., KRÁL, J., SKOCHOVÁ, H.,
KOVÁČOVÁ, V., POHANKA, M., BANĎOUCHOVÁ, H., HILSCHEROVÁ,
K., MELCÁKOVÁ, V., PIKULA, J. Risk of combined exposure
by cyanotoxins, acetylcholinesterase inhibitors and anticoagulants
to Xenopus laevis embryos. Hradec Králové: 18th Interdisciplinary
th
Czech-Slovak Toxicology Conference (TOXCON 2013). 19.06.2013–
21.06.2013. /POSTER/
198. OSIČKOVÁ, J., KOVÁČOVÁ, V., BANĎOUCHOVÁ, H., KRÁL, J.,
SKOCHOVÁ, H., POHANKA, M., NOVOTNÝ, L. Oxidative stress
in birds: Effects of heavy metals and pharmaceuticals. Interlaken,
Switzerland: 49th Congress of the European-Societies of Toxicology,
EUROTOX. 01.08.2013–04.08.2013. /POSTER/
199. PAJER, P., DRESLER, J., KABÍČKOVÁ, H., KUŽELKA, V.,
VELEMÍNSKÝ, P., KLIMENTOVÁ, J., STULÍK, J., PEJCHAL, J.,
ELLEDER, D., BENEŠ, V., MEYER, H., DUNDR, P., HUBÁLEK, M.,
PÍŠA, L. Variola virus in historical samples from the National Museum
of Prague. Munich, Germany: Medical Biodefense Conference 2013.
22.10.2013–25.10.2013. /POSTER/
200. PÁRAL, J., LOCHMAN, P., ŠIMEK, J. MASCAL. Praha: Mezinárodní
kongres AWHP. 17.09.2013–17.09.2013.
201. PÁRAL, J. The role of military surgery in the current system of medical
services of the Army of Czech Republic. Jívová: Odborné zaměstnání
Hlavního lékaře SpS. 23.05.2013–24.05.2013.
202. PÁRAL, J., LOCHMAN, P., PAVLÍK, M. Glue versus stapled
anastomosis of the colon; comparison of resistance to intraluminal
pressure: an experimental study. Tel Aviv, Israel: 4th World Congress
for the Advancement of Surgery. 28.10.2013–30.10.2013. /POSTER/
203. PÁRAL, J., PLODR, M. Czech field surgical team in Afghanistan.
Olomouc: 8. Olomoucké dny urgentní medicíny. 15.05.2013–
17.05.2013.
204. PÁVKOVÁ, I. Comparative proteome analysis of Francisella tularensis
after interaction with host cell. Hradec Králové: 3. neformální
proteomické setkání. 21.11.2013–22.11.2013.
205. PAVLÍK, V., HLÚBIK, P., FAJFROVÁ, J., NAVRÁTIL, P. Current
preventive program in the Army of the Czech Republic. Nový Smokovec,
Slovakia: 21. vedecko-odborná konferencia s medzinárodnou účasťou
Životné podmienky a zdravie. 23.09.2013–25.09.2013.
206. PAVLÍK, V., HLÚBIK, P., FAJFROVÁ, J. Prevention of obezity
in the army of the Czech Republic. Teplice: Výživa a zdraví.
18.09.2013–19.09.2013. /POSTER/
207. PAVLÍK, V., HLÚBIK, P., FAJFROVÁ, J. Primary and secondary
prevention on obesity in the Army of the CR. Hradec Králové: 13.
konference odborné Společnosti vojenských lékařů, farmaceutů
th
208. PAVLIŠ, O., POHANKA, M., SOBOTKA, J. Application of melatonin
to mice infected by tularemia. Kutná hora: 16. konference o laboratorních zvířatech. 15.05.2013–17.05.2013.
209. PETRÁNEK, K., VANĚK, J., JEŽEK, B., JANEČKA, P. Robust image
comparison
using
mutual
information.
Horní
Lomná:
33.
konference geometrii a grafice. 09.09.2013–12.09.2013.
210. PLZÁKOVÁ, L. My theme of thesis. Velká Úpa: Výroční zasedání ÚMP
a CPS za rok 2013. 28.11.2013–29.11.2013.
211. POHANKA, M. Cholinesterases and their application in biosensors
construction. Brno: Excelence doktorského studia na AF Mendelu
pro navazující evropskou vědecko-výzkumnou kariéru. 18.10.2013–
18.10.2013.
212. POHANKA, M., ADAM, V., KZEK, R. Electrochemical assay
of butyrylcholinesterase in biological samples. Brno: 13. Pracovní
setkání fyzikálních chemiků a elektrochemiků. 29.05.2013–30.05.2013.
system using HI-6. Baltimore, USA: 6th International Congress
on Bacteriology and Infection Diseases. 20.11.2013–22.11.2013.
214. POHANKA,
M.,
ŠTĚTINA,
R.,
SVOBODOVÁ,
H.,
RUTTKAY_NEDECKÝ, B., JÍLKOVÁ, M., SOCHOR, J., SOBOTKA, J.,
ADAM, V., KIZEK, R. Sulfur mustard causes oxidative stress and
depletion of antioxidants in organs of wistar rats. Brno: 37. Brněnské
onkologické dny a 27. Konference pro nelékařské zdravotnické
pracovníky. 18.04.2013–19.04.2013. /POSTER/
system using HI-6. Washington, USA: 62nd ASTMH. 13.11.2013–
17.11.2013. /POSTER/
216. POHANKA, M. Cholinesterases and their use for assay of poisons. 1.
Lékařská fakulta Univerzity Karlovy, Praha: Výroční zasedání institutu
Danone. 02.12.2013–02.12.2013.
217. PRAVDOVÁ, L., JAKL, M. The failure of antiplatelet therapy. Hradec
Králové: 8. fakultní vědecká konference studentské tvůrčí činnosti.
24.09.2013–24.09.2013.
218. PROCHÁZKA, M., AGH, K. Active shooter – Metro 2013. Hradec
Králové: 10. ročník celostátní konference Medicína katastrof.
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219. PROCHÁZKA, M., HALAJČUK, T. Trauma planning of health care
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220. PROCHÁZKA, M., FIŠER, V. Trauma planning of the inpatient and one
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221. PROCHÁZKA, M., JEŽEK, T. 10 years of the Disaster Medicine
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222. PROCHÁZKA, M., HALAJČUK, T. Financing of the pre-hospital
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223. PROCHÁZKA, M., FIŠER, V. Trauma planning – recent reality and
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224. PRYMULA, R., CHLÍBEK, R. Pneumococcal disease and new
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225. PRYMULA, R. New vaccine for the prevention of infectious diseases.
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226. PRYMULA, R. Two-dose toddler vaccination with investigational
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227. PRYMULA, R. Antibody persistence one year after vaccination with four
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228. PRYMULA, R. Measles: whan can we learn about recent outbreaks?
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229. PRYMULA, R. European studies: A3L39/40. Lyon, France: Hexacima
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230. PRYMULA, R. Communication through new media: Is there a place
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231. PRYMULA, R. Communication through new media: Is there a place
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232. PRYMULA, R. Current European recommendation for use of PCV
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233. PRYMULA, R. News in vaccination of children and views
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234. PRYMULA, R. PCV in prevention of pneumococcal diseases. Skopje,
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235. PRYMULA, R. Development of the vaccination calendar in Europe.
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236. PRYMULA, R. Two-dose toddler vaccination with investigational
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237. PSUTKA, J., MALÝ, V., HUMLÍČEK, V., MRVEČKA, P. MEDEVAC
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238. PUTZOVÁ, D. Fast protein liquid chromatography. Hradec Králové:
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239. RUTTKAY-NEDECKÝ, B., HYNEK, D., MAŠKOVÁ, D., NEJDL, L.,
POHANKA, M., ADAM, V., KIZEK, R. Use of electrochemical methods
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240. SHESHKO, V. Expression of recombinant proteins. Hradec Králové:
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241. SHESHKO, V., PUTZOVÁ, D., STULÍK, J. Identification, cloning,
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242. SHESHKO, V., PUTZOVÁ, D., STULÍK, J. Identification, cloning,
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243. SCHMIDT, M. DsbA – never ending story. Velká Úpa: Výroční zasedání
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244. SCHMIDT, M., STULÍK, J., PÁVKOVÁ, I. The role of cis-proline residue
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245. SLANINKA, I., KLEIN, L., ČÁP, R., HOŠEK, F., HASENÖHRLOVÁ, L.
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246. SMETANA, J. Everything you wanted to know about vaccination and did
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247. SMETANA, J., CHLÍBEK, R., BOŠTÍKOVÁ, V. Present vaccination
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248. SMETANA, J., KOSINA, P. Vaccination in questions and answers –
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250. SMETANA, J., KOSINA, P. Questions and answers on the practice
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251. SMETANA, J. Vaccinations recommended for the adult population.
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253. SMETANA, J., KOSINA, P. Questions and answers on the practice
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254. SMETANA, J. News vaccination in adults. Praha: Školení lékařů
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257. SMETANA, J., CHLÍBEK, R., BOŠTÍKOVÁ, V. Vaccination against
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259. SNAPE, M., FINN, A., HEATH, P., BONA, G., ESPOSITO, S.,
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260. SNAPE, M., FINN, A., HEATH, P., BONA, G., ESPOSITO, S.,
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261. SOUKUP, O., KORÁBEČNÝ, J., ŠPILOVSKÁ, K., MUSÍLEK, K., JUN,
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262. SOUKUP, O. Acetylcholinesterase. St.
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265. STŘÍTECKÁ, H. Dietary fat in prevention of CVD. Praha: Výživové
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266. STŘÍTECKÁ, H. Nutrition for children. Praha: Vzdělávací seminář Dexter
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267. STŘÍTECKÁ, H. Human nutrition. Hradec Králové: Akreditovaný
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268. STŘÍTECKÁ, H. Nutrition of pregnant and breastfeeding. Praha:
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269. STŘÍTECKÁ, H. Fluid intake, quality of beverages in the trade market.
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271. STŘÍTECKÁ, H., HLÚBIK, P. Effects to satiation and weight reduction
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272. STŘÍTECKÁ, H. Nutrition as a factor for preventable of civilization
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273. STŘÍTECKÁ, H. Prevalence of overweight and obesity in the project
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275. STŘÍTECKÁ, H., ZMRZLÁ, H. What children prefer in the diet and why?
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278. STŘÍTECKÁ, H. Workshop – practical dietary advice. Poděbrady:
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280. STŘÍTECKÁ, H. The nutritional care in the treatment of obesity. Hradec
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281. STŘÍTECKÁ, H., ZAMRAZILOVÁ, H., DIVOKÁ, J., TLÁSKAL, P.,
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282. STŘÍTECKÁ, H., ZMRZLÁ, H., HLÚBIK, P. Is there any differences? –
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283. STŘÍTECKÁ, H. The possibilities of nutritional counselling in child
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284. STŘÍTECKÁ, H. Rules for the design and assessment of eating records.
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285. STŘÍTECKÁ, H. Basics of anatomy of the digestive tract – physiology
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286. STŘÍTECKÁ, H. Basics of biochemistry – metabolism of protein,
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287. STULÍK, J. Quantitative proteomics analysis of macrophage rafts
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288. STULÍK, J. Quantitative proteomic identification of macrophage proteins
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289. STULÍK, J. Quantitative proteomic identification of macrophage proteins
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290. STULÍK, J. Scientific work of Institute of Molecular Pathology year 2013.
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292. ŠEPSOVÁ, V., ŽĎÁROVÁ KARASOVÁ, J., DRTINOVÁ, L.,
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293. ŠEPSOVÁ, V., ŽĎÁROVÁ KARASOVÁ, J., DRTINOVÁ, L., ZEMEK, F.,
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294. ŠEPSOVÁ, V., ŽĎÁROVÁ KARASOVÁ, J., SOUKUP, O.,
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295. ŠEPSOVÁ, V. Observation of cholinesterase inhibitor's effects
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296. ŠEPSOVÁ, V., ŽĎÁROVÁ KARASOVÁ, J., SOUKUP, O. Testing
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297. ŠINKOROVÁ, Z., ZÁRYBNICKÁ, L., NAVRÁTIL, L., ČASTULÍK, P. A
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298. ŠINKOROVÁ, Z., ZÁRYBNICKÁ, L., ČASTULÍK, P. Evaluation
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300. ŠMEJKAL, K. Humeral shaft fractures. Plzeň: Bohemian-Bavarian
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301. ŠMEJKAL, K. Fractures of blades. Plzeň: Bohemian-Bavarian Congress.
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303. ŠPIDLOVÁ, P., STRAŠKOVÁ, A., BALONOVÁ, L., ŽÁKOVÁ, J.,
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304. ŠPIDLOVÁ, P., ŠENITKOVÁ, I. Protein – protein interactions: new
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309. ŠPLIŇO, M. Systemic review of influenza. Malaga, Spain: Advisory
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310. ŠPLIŇO, M., BOŠTÍKOVÁ, V. Measles – recurring problem in Europe.
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311. ŠPLIŇO, M., BOŠTÍKOVÁ, V. Hepatitis C Virus – The discovery
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313. ŠTĚTINA, R., HRNČIARIKOVÁ, D., HRNČIARIK, M., FIKROVÁ, P.,
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314. ŠTĚTINA, R., JOŠT, P., SVOBODOVÁ, H. Different repair of interstrand
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315. ŠUBRT, Z., FERKO, A., ČEČKA, F., JON, B. Laparoscopic vs. open
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316. ŠUBRT, Z., FERKO, A., ČEČKA, F., JON, B. Postoperative morbidity
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317. ŠUBRT, Z. First experiences with the generator Caiman in FNHK.
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318. ŠUBRT, Z. Casereport of a patient with metastatic colorectal carcinoma.
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319. ŠUBRT, Z., FERKO, A., ČEČKA, F., JON, B. Rare primary tumors –
case reports. Plzeň: 40. česko-slovenský chirurgický kongres
s mezinárodní účastí a 6. kongres chirurgie jater, žlučových cest
a pankreatu. 11.09.2013–13.09.2013.
320. ŠUBRT, Z., FERKO, A., ČEČKA, F., JON, B. Surgical treatment of liver
metastases for colorectal cancer: analysis of predictive factors. Plzeň:
40. česko-slovenský chirurgický kongres s mezinárodní účastí a 6.
kongres chirurgie jater, žlučových cest a pankreatu. 11.09.2013–
13.09.2013.
321. ŠUBRT, Z., FERKO, A., ČEČKA, F., JON, B. Iatrogenic bile duct injury.
Ještěd: Pracovní den sekce mladých chirurgů ČCHS. 24.10.2013–
25.10.2013.
322. ŠUBRT, Z., FERKO, A., ČEČKA, F., JON, B. Laparoscopic right hand
extended hemihepatektomie for liver metastases of colorectal cancer.
Bratislava, Slovakia: 67. chirurgický deň Kostlivého. 06.12.2013–
06.12.2013.
323. ŠUBRT, Z. First experiences with the generator Caiman in FNHK.
Hradec Králové: Techniky hemostázy – elektrochirurgie a lokální
hemostatika. 22.11.2013–22.11.2013.
324. ŠUBRT, Z. How can hunt appendectomy. Harrachov: 17. Harrachovské
chirurgické dny. 13.06.2013–14.06.2013.
325. ŠUBRT, Z. Laparoscopic liver resection for liver metastases of colorectal
cancer. Hradec Králové: 14. Bedrnův den. 18.04.2013–19.04.2013.
326. TICHÝ, A., ŠALOVSKÁ, B., FABRIK, I., VÁVROVÁ, J. Comparison
of resins for metal oxide affinity chromatography with mass spectrometry
detection for the determination of phosphopeptides. Minneapolis, USA:
61st Conference of American Society for Mass Spectrometry.
09.06.2013–13.06.2013. /POSTER/
th
327. TICHÝ, A., ŠALOVSKÁ, B., FABRIK, I., VÁVROVÁ, J., ŘEZÁČOVÁ, M.
Radio-sensitization of human leukemic cells HL-60 by ATR-kinase
inhibitor (VE-821). Hradec Králové: 13. konference odborné Společnosti
24.10.2013–24.10.2013. /POSTER/
328. TONEATTO, D., PRYMULA, R., MERRALL, E., KOHL, I., DULL, P.,
VESIKARI, T. Immunogenicity and reactogenicity of two-dose
vaccination with investigational meningococcal B recombinant vaccine
at 24 and 26 months of age. Milan, Italy: 31st Annual ESPID meeting.
28.05.2013–01.06.2013. /POSTER/
329. VAJRYCHOVÁ, M. Protein quantification using stable isotope labeling.
Hradec Králové: Interní výukový seminář laboratorních metod.
19.02.2013–19.02.2013.
330. VAJRYCHOVÁ, M. Analysis of native peptides in pregnancies
complicated by preterm leakage of amniotic fluid. Hradec Králové: 7.
fakultní konference studentů doktorských programů. 01.10.2013–
01.10.2013.
331. VAJRYCHOVÁ, M. Analysis of native peptides in pregnancies
complicated by preterm leakage of amniotic fluid. Velká Úpa: Výroční
zasedání UMP a CPS. 28.11.2013–29.11.2013.
332. VAJRYCHOVÁ, M., TAMBOR, V., KACEROVSKÝ, M., STULÍK, J.,
LENČO, J. Analysis of amniotic fluid proteome and peptidome
in PPROM pregnancies with inflammatory complications. Yokohama,
Japan: The 12th Human Proteome Organisation World Congress (12th
HUPO). 14.09.2013–18.09.2013. /POSTER/
333. VANĚK, J., JEŽEK, B. Computer graphics subjects in computer science
curricula. Praha: Proceedings of the 10th International Conference
Efficiency and Responsibility in Education 2013. 06.06.2013–
07.06.2013.
334. VODIČKA, P., SLYŠKOVÁ, J., ŠTĚTINA, R., VODIČKOVÁ, L.,
NACCARATI, A., KUMAR, R., HEMMINKI, K. Functional DNA repair
tests and their perspectives in molecular epidemiology (experience
with subjects exposed to carcinogens and in cancer patients). Courtyard
by Marriott Philadelphia Downtown, USA: Cancer Epidemiology,
Biomarkers & Prevention, 4th International Conference on Biomarkers &
Clinical Research. 15.07.2013–17.07.2013. /POSTER/
335. VOSEČKOVÁ, A., HRSTKA, Z., PROCHÁZKA, M. Interdiciplinary
preparation of specialists for emergency situations. Hradec Králové: 19.
královéhradecké
ošetřovatelské
dny.
12.09.2013–13.09.2013.
/POSTER/
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336. WITT, P., PSUTKA, J., MALÝ, V. KOT-ZDR Pandur II. Hradec Králové:
13. konference odborné Společnosti vojenských lékařů, farmaceutů
337. ZAMRAZILOVÁ, H., TLÁSKAL, P., BOŽENSKÝ, J., BŘEZKOVÁ, V.,
STŘÍTECKÁ, H., DIVOKÁ, J., FLORIÁNKOVÁ, M., HOSTINSKÝ, J.,
KŘÍSTEK, N., MARÁDOVÁ, E., PACKOVÁ, A. Forum of prevention
childhood overweight and obesity – activation of selected moments
in education and lifestyle in the school environment. Pardubice: Školní
stravování 2013. 14.05.2013–16.05.2013.
338. ZÁRYBNICKÁ, L., ŠINKOROVÁ, Z., VÁVROVÁ, J. The of radiosensitivity of lymphocytes by surface and intracellular phenotyping.
Praha: Odborný seminář průtokové cytometrie. 07.02.2013–08.02.2013.
339. ZÁRYBNICKÁ, L., ŠINKOROVÁ, Z. Flow cytometry. Hradec Králové:
Interní výukový seminář laboratorních metod I. 12.02.2013–12.02.2013.
340. ZÁRYBNICKÁ, L. The biodosimetric study. Fontenay aux Roses,
France: CEA – Institute of Cellular and Molecular Radiobiology.
29.10.2013–28.11.2013.
341. ZÁRYBNICKÁ, L. Molecular mechanisms of DNA reparation. Hradec
Králové: Seminář – Nové pohledy na účinek ionizujícího záření na živý
organismus. 11.12.2013–11.12.2013.
th
INDEX
INDEX
DRTINOVÁ, L. 29, 104, 109, 111,
115, 125, 130, 133, 146, 150,
159, 160, 161
DUŠEK, T. 48
DUŠKOVÁ, K. 52, 57
A
ANTONINOVÁ, J. 29
ANTOŠ, K. 59, 121, 123
B
BAJGAR, J. 14, 65, 88, 114, 117,
121, 122, 128, 144, 146
BALONOVÁ, L. 68, 132, 133, 160
BEDNARČÍK, P. 57, 118, 134
BENDOVÁ, T. 52
BERNARDOVÁ, M. 38
BLANAŘ, R. 25, 55, 88
BLAŽEK, P. 36
BOCKOVÁ. I. 74
BOŠTÍK, P. 3, 16, 25, 26, 29, 31,
32, 33, 34, 35, 42, 43, 44, 71,
72, 75, 76, 77, 88, 98, 99, 100,
101, 103, 110, 114, 115, 119,
126, 132, 147
BOŠTÍKOVÁ, V. 31, 34, 35, 38,
42, 43, 44, 72, 79, 80, 88, 98,
100, 101, 103, 110, 114, 115,
116, 119, 120, 126, 129, 130,
132, 140, 142, 155, 156, 161
BRNDIAR, M. 27, 28, 45, 137
C
CABAL, J. 65, 107, 108, 129, 149
ČÁP, R. 48, 49, 126, 132, 155
ČMEDLOVÁ, P. 52, 57
D
DOBEŠ, D. 48, 49, 105, 109, 110,
133
DOHNALOVÁ, L., 76
DOLEŽELOVÁ, M. 52
DRESLER, J. 15, 68, 94, 133,
135, 151
th
E
ETFLAIŠOVÁ, P. 74
F
FABRIK, I. 68, 104, 111, 133,
134, 162, 163
FAJFROVÁ, J. 57, 92, 108, 116,
118, 122, 129, 134, 151
FORETOVÁ, Z. 68
FUČÍKOVÁ, A. 68, 71, 93, 95,
133, 135
FUSEK, J. 26, 59, 109, 113
G
GRÖGER, T. 52, 135
H
HALAJČUK, T. 59, 61, 76, 96,
116, 119, 121, 135, 143, 153
HANOVCOVÁ, I. 33, 38, 43, 71,
98, 114, 116, 119
HEJČOVÁ, J. 59
HERMAN, D. 29, 150
HLAVÁČKOVÁ, H. 59
HLÚBIK, P. 26, 57, 78, 80, 105,
115, 116, 119, 122, 124, 125,
129, 134, 136, 151, 157, 158
HORÁČEK, J. 26, 45, 79, 80,
105, 112, 116, 124, 126, 127,
128, 136, 137, 138, 142, 148
HRABINOVÁ, M. 29, 32, 101,
103, 106, 117, 127, 135, 147,
148, 150
INDEX
HRDLIČKOVÁ, L. 36
HRSTKA, Z. 26, 27, 28, 59, 61,
96, 138, 139, 163
HUMLÍČEK, V. 55, 116, 122, 123,
139, 154
HUSÁROVÁ, M. 57
CH
CHLÍBEK, R. 15, 25, 26, 38, 39,
40, 41, 42, 75, 76, 77, 78, 79,
88, 96, 97, 99, 103, 105, 107,
110, 112, 114, 115, 116, 118,
119, 121, 122, 123, 126, 127,
128, 129, 130, 132, 133, 139,
140, 141, 142, 149, 153, 155,
156
J
JAKL, M. 26, 45, 105, 124, 126,
137, 138, 142, 152
JANOUCH, J. 59
JAREŠOVÁ, L. 59, 142, 143
JEBAVÝ, L. 26, 45, 47, 80, 88,
96, 105, 116, 119, 124, 126,
127, 128, 136, 137, 138, 143,
148
JEŽEK, B. 59, 61, 96, 116, 119,
121, 122, 123, 135, 142, 143,
144, 152, 153, 163
JOŠT, P. 29, 65, 108, 144, 161
JUN, D. 26, 29, 33, 34, 43, 61,
71, 95, 98, 103, 106, 111, 113,
115, 117, 120, 127, 128, 130,
131, 135, 144, 145, 147, 148,
149, 150, 156, 157
JUNKOVÁ, I. 74
K
KAČEROVSKÝ, J. 45, 105, 111,
143, 149, 163
KAISLEROVÁ, L. 29, 35, 44, 99,
114, 115
th
KASSA, J. 13, 26, 32, 60, 65, 66,
75, 76, 77, 79, 88, 89, 100,
102, 106, 124, 130, 133, 144,
145, 146, 148, 149, 150, 161
KLEIN, L. 26, 48, 50, 75, 77, 80,
89, 116, 117, 118, 119, 126,
132, 145, 155
KLIMENTOVÁ, J. 68, 110, 133,
145, 151
KOMÁREK, V. 36
KONŠTACKÝ, S. 27, 28, 52, 117
KORÁBEČNÝ, J. 16, 65, 80, 92,
106, 111, 113, 117, 120, 130,
132, 133, 144, 145, 147, 150,
156, 157, 159, 160, 161
KOŠŤÁLOVÁ, L. 38
KRAČMAROVÁ, A. 29, 65, 117,
124, 128, 133, 146, 150
KROČOVÁ, Z. 16, 33, 34, 43, 68,
71, 72, 77, 78, 89, 92, 98, 99,
100, 122, 135, 146, 147
KRUTIŠ, J. 52
KRUTIŠOVÁ, P. 52
KUBELKOVÁ, K. 26, 29, 76, 77,
78, 122, 146, 147
KUČA, K. 16, 26, 29, 32, 33, 34,
60, 61, 66, 77, 80, 89, 95, 99,
100, 101, 103, 106, 107, 108,
111, 112, 113, 115, 117, 118,
120, 127, 128, 129, 130, 131,
132, 133, 135, 136, 142, 144,
145, 147, 148, 149, 150, 156,
157, 160, 161
KULICH, M. 59
KUPSA, T. 45, 79, 80, 105, 116,
124, 126, 127, 128, 136, 137,
138, 148
L
LAŠÁK, P. 59
LEGERSKÁ, K. 38
INDEX
LENČO, J. 68, 70, 95, 104, 105,
111, 135, 148, 149, 163
LINK, M. 68, 133, 138, 149
LOCHMAN, P. 26, 48, 49, 77,
129, 151
LUKŠÍKOVÁ, L. 68
M
MACELA, A. 15, 33, 43, 68, 71,
98, 108, 122, 135, 146, 147
MACHAČOVÁ, I. 45
MALÍKOVÁ, M. 38
MALÝ, V. 55, 105, 119, 123, 124,
126, 137, 142, 154, 164
MAREK, J. 38, 129, 149
MATOUŠEK, R. 52, 149
MAZUROVÁ, I. 29
MERVARTOVÁ, L. 62
MISÍK, J. 32, 60, 65, 66, 77, 79,
80, 93, 100, 106, 107, 108,
118, 124, 129, 130, 133, 144,
145, 146, 149, 150, 156, 159
MÍŠKOVÁ, L. 55
MÍŠKOVÁ, Z. 27
MRVEČKA, P. 55, 122, 123, 154
MUSÍLEK, K. 26, 32, 60, 65, 66,
76, 77, 80, 100, 103, 106, 111,
112, 113, 117, 128, 130, 132,
136, 142, 144, 145, 147, 148,
149, 150, 156, 157, 160, 161
P
PÁRAL, J. 8, 17, 24, 25, 26, 48,
49, 50, 77, 95, 102, 129, 151
PÁVKOVÁ, I. 68, 108, 110, 151,
155
PAVLÍK, M. 32, 74, 101
PAVLÍK, V. 26, 57, 65, 103, 108,
111, 113, 116, 118, 122, 129,
131, 134, 148, 149, 151
th
PAVLIŠ, O. 65, 93, 109, 110, 118,
146, 152
PEJCHAL, J. 29, 31, 34, 43, 65,
72, 96, 100, 103, 106, 108,
112, 122, 147, 151
PEREGRINOVÁ, J. 57
PÍRKOVÁ, J. 57
POHANKA, M. 27, 28, 29, 32, 34,
61, 79, 80, 89, 104, 105, 106,
108, 109, 110, 111, 112, 115,
118, 120, 122, 124, 125, 129,
133, 146, 150, 151, 152, 154
POTÁČ, M. 27, 28, 55
PROCHÁZKA, M. 25, 27, 28, 59,
61, 76, 95, 116, 119, 121, 123,
135, 143, 152, 153, 163
PRŮCHOVÁ, Š. 62
PRYMULA, R. 11, 12, 14, 15, 26,
38, 40, 41, 90, 99, 107, 112,
119, 122, 123, 129, 153, 154,
156, 163
PSUTKA, J. 13, 26, 55, 123, 154,
164
PUDÍK, P. 27, 28
PUDÍKOVÁ, M. 74
R
RESLOVÁ. E. 65
ROHLENA, M. 27, 28
RŮŽIČKA, M. 55, 116, 119
RYDRYCH, J. 36
Ř
ŘEHULKA, P. 34, 43, 68, 72, 100,
104, 107, 110, 111, 133
S
SHESHKO, V. 29, 154, 155
SCHMIDT, M. 29, 68, 108, 110,
135, 155
SLAVÍK, J. 74
INDEX
SMETANA, J. 15, 26, 27, 28, 35,
38, 40, 41, 42, 44, 77, 79, 90,
97, 99, 103, 110, 114, 115,
116, 117, 119, 126, 128, 129,
130, 132, 133, 140, 141, 142,
145, 146, 155, 156
SOLÁROVÁ, A. 38
SOUKUP, O. 59, 80, 104, 106,
111, 117, 118, 129, 130, 145,
147, 148, 149, 156, 157, 159,
160
STŘÍTECKÁ, H. 27, 28, 57, 79,
80, 90, 105, 116, 119, 120,
124, 125, 133, 136, 157, 158,
159, 164
STULÍK, J. 14, 26, 27, 28, 68, 70,
71, 76, 79, 90, 95, 96, 101,
103, 104, 108, 110, 133, 135,
138, 151, 154, 155, 159, 160,
163
SVOBODOVÁ, H. 65, 78, 109,
129, 152, 161
Š
ŠAFÁŘOVÁ, M. 68
ŠEPSOVÁ, V. 65, 76, 77, 79,
106, 111, 112, 113, 120, 125,
130, 133, 144, 145, 146, 147,
150, 159, 160, 161
ŠIMEK, J. 48, 151
ŠINKOROVÁ, Z. 26, 62, 78, 80,
107, 112, 122, 146, 147, 160,
164
ŠÍSTKOVÁ, J. 52
ŠKRANCOVÁ, V. 65
ŠMEJKAL, K. 15, 48, 79, 145,
160
ŠMÍRA, P. 27, 28
ŠOŠOVIČKOVÁ, R. 38, 140
ŠPIDLOVÁ, P. 68, 79, 110, 160
th
ŠPILOVSKÁ, K. 65, 111, 130,
132, 133, 135, 145, 146, 156,
159, 160, 161
ŠPLIŇO, M. 26, 38, 79, 90, 103,
110, 115, 116, 119, 120, 130,
140, 142, 161
ŠTĚTINA, R. 27, 28, 65, 78, 90,
104, 109, 129, 144, 152, 161,
163
ŠUBRT, Z. 15, 26, 27, 28, 48, 51,
78, 96, 103, 115, 120, 126,
130, 131, 134, 161, 162
T
TICHÝ, A. 27, 28, 45, 62, 63, 92,
98, 100, 105, 108, 111, 112,
122, 126, 136, 137, 162, 163
TOMÁŠIK, M. 25
TÓTHOVÁ, I. 29
U
UHLÍŘOVÁ, J. 65
VAJRYCHOVÁ, M. 68, 75, 77,
105, 149, 163
VANĚK, J. 59, 61, 96, 116, 119,
121, 122, 123, 135, 142, 143,
144, 152, 163
VÁVROVÁ, J. 26, 62, 103, 104,
107, 108, 111, 112, 122, 162,
163, 164
VÍCHOVÁ, E. 36
VOPLATKOVÁ, Z. 27, 28, 36
VOŽENÍLKOVÁ, K. 38
W
WITT, P. 55, 119, 164
Z
ZAHRADNÍČKOVÁ, J. 48
ZÁRYBNICKÁ, L. 27, 62, 76, 79,
112, 122, 146, 147, 160, 164
ZEDNÍČEK, J. 36
ZIKOVÁ, J. 36
INDEX
Ž
ŽÁKOVÁ, J. 29, 160
ŽĎÁROVÁ KARASOVÁ, J. 27,
32, 34, 59, 60, 61, 66, 75, 77,
th
95, 100, 106, 111, 112, 113,
117, 120, 125, 128, 130, 131,
144, 145, 146, 147, 148, 150,
156, 159, 160
2013 Annual Report was edited and published by the Faculty of Military
Health Sciences, University of Defence, Hradec Králové, Czech Republic
Editor: Mgr. Hana Hlaváčková
Computer work: Lenka Hrdličková, Mgr. Hana Hlaváčková
(using the OBD 3 and the VERSO programs)
Printing: 200
Printed: University of Defence
Contact address:
Fakulta vojenského zdravotnictví
Třebešská 1575
CZ-500 01 Hradec Králové
Tel.: +420 973 253 001
Fax: +420 495 513 018
E-mail: [email protected]
E-mail: [email protected]
Univerzita obrany, Brno, CZ
ISBN 978-80-7231-355-6

annual report 2013 - Univerzita obrany

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