Nexar - LGC Group

Nexar® Specifications
GENERAL
Typical Modules: W: 28.7 cm (11.3”) H: 64.0 cm (25.2”) D: 81.3 cm (32”)
Unwind/Rewind Modules: W: 43.2 cm (17”)
Incubator Module: W: 57.6 cm (22.7”) H: 112.1 cm (44.1”) D: 81.3 cm (32”)
AmbiStore: W: 130.8 cm (51.5”) H: 162.3/96.0 cm (63.9”/37.8”) D: 97.3 cm (38.3”)
ELECTRICAL
Supply: 115/230 V 50/60 Hz auto select
Power Rating: 400 W typical 1,200 W max
Fuse Rating: 20A (@115V)
CONTROLLER
Ethernet-based PC controller
DATA INTERFACE
Standard interface options available
SUPPORTED PLATE
CONFIGURATIONS
96 and 384
PIPETTING HEAD
CYBIO 384 HEAD (By CYBIO)
Mechanism: Simultaneous air displacement
Douglas Scientific Suggested Volume Range: 600 nL to 2,500 nL (dependent on tip vol.)
Manufacturer Precision: CV < 2%, at 1.0 µL
See Manufacturer’s specs
PLATE HANDLER
Capacity: Per user requirement
JET DISPENSER
DISPENSE JET
Mechanism: Single jet solenoid micro-valve
Volume Range: 750 nL to 1,250 nL
Precision: CV < 7%
Channels: 4
DISPENSE JET 2.0
Volume Range: 250 nL to 2,500 nL
Precision: CV < 7%
Channels: 4
OTHER
Air: 8.5 scfm @ 80 psi
Water: Supply R.O. Water (Max 15L/Hr)
CERTIFICATIONS
CE for electrical safety
Nexar®
Inline Liquid Handling
and Assay Processing System
FlexJet™
Mechanism: Single jet solenoid micro-valve
Volume Range: 250 nL to 2,500 nL
Precision:
>250nL–7%
>300nL to 400nL–6.5%
>500NL to 2,500nL–4.5%
Channels: 4 or 8
The Nexar® System supports ultra high-throughput
processing of samples and assays in a remarkably fast,
automated, inline instrument. Engineered to operate
with precision and accuracy, the Nexar capitalizes on
the innovative Array Tape® consumable. Nexar modules
store and retrieve samples and reagents, dispense in
sub-microliter volumes into 96- and 384-well format
arrays, provide incubation, thermal cycling, and more
to support multiple laboratory applications. In addition
to increasing throughput and decreasing cost per
data point, the Nexar System delivers consistent, high
quality data.
Flexible Solutions
The Array Tape Platform is a flexible and scalable solution designed to
support ultra high-throughput applications. Realize the benefits of a fully
integrated, inline system today, while positioning your lab for the demands
of tomorrow.
Modularity
The Nexar System is based on configurable modules to meet the needs
of your specific applications. As laboratory processes change over time,
your investment will be protected as our system can be adapted to your
evolving needs. Such modularity allows you to embrace change with
simplicity and minimal cost.
Applications
End-Point PCR
End-Point Isothermal
DNA Amplification
Application not listed?
Check out our Custom Automation
services inside.
Support
At Douglas Scientific, we pride ourselves on going above
and beyond normal service standards for our clients. Rest
assured we will be there every step of the way ensuring our
solutions exceed your expectations.
ŸPost-Installation Support & Service includes: 12-month
comprehensive warranty, industry leading post warranty
support programs, and 24 hours a day, 7 days a week
online support services.
ŸPre-Installation Process includes: site review, factory
acceptance testing, and certified technician training.
ŸInstrument and Software Optimization: Highly specific
processes and protocols may require instrument and/or
software modifications. The Douglas Scientific team is skilled
at delivering optimized solutions to meet your needs.
ŸInstallation & Training includes: onsite installation, end
user training, and site acceptance testing.
The products of Douglas Scientific LLC are not
FDA-approved for use in human diagnostic procedures.
Exclusive distributor of the Douglas Scientific®
Array Tape® Platform in Europe, Middle East and Africa.
Unit 1-2 Trident Industrial Estate
Pindar Road
Hoddesdon • Herts • EN11 OWZ
United Kingdom
4/15
Tel: +44 (0)1992 470 757
Fax: +44 (0) 1438 900 670
Email: [email protected]
www.lgcgroup.com/douglas-scientific
Manufactured by:
Exclusive distributor of the
Douglas Scientific® Array Tape® Platform
in Europe, Middle East and Africa.
Achieve quality data
with a flexible, high-throughput system
at a dramatically lower cost per data point
A look inside
Nexar Optimized for End-Point PCR
End-Point PCR
The Nexar, Soellex® water bath and Araya® detector provide an
ideal platform for end-point PCR. True high throughput capabilities
with miniaturized reaction volumes and reduced consumable
costs create a highly efficient, data-generating system to provide
dramatic decreases in cost per data point and equally impressive
increases in throughput. The system is compatible with crude DNA
preparation and offers flexibility in chemistry selection.
The Nexar Optimized for End-Point Isothermal DNA Amplification
is configured to provide walk- away operation by integrating liquid
handling, incubation and detection in one instrument. Leverage
DNAble® chemistry by EnviroLogix™ to achieve exponential Nucleic
Acid amplification at one constant temperature. Go from sample to
answer in 15 minutes or less.
Custom Automation Service
Name the high throughput application, and we’ll put the power of
Douglas Scientific innovation to work for you. The team at Douglas
Scientific delivers extensive experience in motion and movement,
automated processing, and high throughput applications such as:
• Sample Purification/Extraction
• Liquid Handling
• Miniaturized Reactions
• Incubation
• Thermal Cycling
• Detection
• High Capacity PCR
• Customized Compound
Embedding in Array Tape
• And more!
This experience, coupled with our rapid development capabilities
provides customers with a truly responsive collaborative
development partner.
Chemistry
Seal the array
Product
Parallel
Channel
CyBio
End-Point Isothermal DNA Amplification
Add reagent
Ÿ Parallel channel pipetting from plates using the CyBio LDH head provides
rapid sample and reagent dispense into Array Tape using 96- or 384- tips
in either full or quadrant stamping in a range of 600 nL to 800 nL.
FLUID HANDLING
Applications
Dry sample (optional)
The Nexar System supports sample and reagent processing with
interchangeable dual head dispensing. An assortment of flexible dispensing
options can be tailored to your individual process.
Ÿ Non-contact, multi-channel, high speed dispensing a dispense range of
250 nL to 2,500 nL.
The inline configuration of the Nexar®
provides automation for varied
protocols. Take a closer look at a few
standard modules.
Dispense sample and wash pipette tips
Automated Liquid Handling
The Nexar is an open system supporting most PCR fluorescencebased chemistries including industry-leading brands such as LGC’s
KASP genotyping chemistries, Life Technologies TaqMan® and more.
Multi-Channel
Number of Channels
4
8
X
Dispense Jet
X
X
FlexJet™
X
X
X
96
384
Manufacturer Validated
Volume Range
Nexar CVs*
Nexar Validated
Volume Range
X
X
0.2 µL to 25 µL
< 6.6% with 10 µL tips
< 4.7% with 25 µL tips
0.6 µL – 25 µL
NA
< 7%
750 nL to 1250 nL
NA
4.5% – 7%
250 nL to 2,500 nL
*CVs are documented using Artel.
Plate Storage
The standard serial plate delivery module accommodates up to 20 plates.
For larger plate quantities, the Nexar integrates with HighRes Biosolutions’
AmbiStore™; a high capacity, random access carousel (managing up to 672,
96- or 384-well low-profile plates in the M model).
Tape Sealing
Array Tape® seal management is achieved through the use of an inline tape
sealing module. After liquid dispensing is complete, Array Tape is automatically
sealed to secure the reaction in the wells and eliminate the potential for
amplicon contamination. An optional chiller plate is available to delay sample
reactions prior to amplification and detection.
Incubation
An inline incubation module allows for unattended sample amplification at
ambient or elevated temperatures. Inline incubation modules enable walk-away
end-point isothermal DNA amplification processing.
Intellics® Software
Intellics® provides centralized data management and instrument monitoring
through the Dashboard. Achieve advanced instrument operation and
intelligent run optimization with the Array Builder™, a protocol generator.
IntelliScore® streamlines the analysis of your data. All applications are
web-based, for ease of access and convenient maintenance.
Scientific Support
Our expert scientific team offers a variety of services to ensure your lab gets
up and running, produces reliable data, and runs at maximum efficiency.
Whether you’re developing new assays or want help optimizing existing assays,
Douglas Scientific will be there for you.
AmbiStore M Model