Department of Children`s Surgery - Rady Children`s Hospital

Transcription

Department of
Children’s Surgery
BIENNIAL REPORT 2011-2013
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Table of Contents
INTRODUCTION
1
DIVISIONAL REPORTS:
HEART INSTITUTE
2
MATERNAL FETAL MEDICINE
16
NEUROSURGERY
22
OPHTHALMOLOGY
30
ORTHOPEDICS & SCOLIOSIS
34
PEDIATRIC OTOLARYNGOLOGY
48
PATHOLOGY
64
SURGERY & TRAUMA
70
PEDIATRIC UROLOGY
74
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Dear Friends & Colleagues,
We are excited to present the third biennial Rady Children’s Specialists of San Diego, A Medical Foundation,
Department of Children’s Surgery 2011-2013 report. This report is a culmination of the accomplishments of our
surgeons and surgeon-scientists following the inception of the medical foundation at Rady Children’s Hospital-San
Diego (RCHSD) in September 2009.
The Department of Surgery of the medical foundation includes clinically active members of the hospital divisions of:
Cardiovascular Surgery
Maternal and Fetal Medicine
Neurosurgery
Pediatric General Surgery
Ophthalmology
Orthopedics
Otolaryngology and
Urology
Head and Neck Surgery
The medical practice foundation has provided a structure for the surgical faculty to work collaboratively to improve
surgical clinical care, education, and enhance research activities. Members of the department are faculty in the
Departments of Surgery, Orthopedics, Reproductive Medicine and Neurosciences at the University of California, San
Diego (UC San Diego). The foundation has fostered even greater synergy between surgical colleagues at UC San Diego
and RCHSD. This partnership has allowed the department to continue to provide world class surgical care for the
region’s patients and families.
RCHSD has continued to grow its surgical volume, performing greater than 21,000 operative cases in the last year.
We are also very close to performing our first cardiac transplant procedure after successfully attracting a world class
pediatric cardiac transplant surgeon. Our new Cardiovascular Intensive Care Unit is providing the best of care to our
Heart Institute patients.
A new surgical academic fund has been created in partnership with RCHSD to help finance surgical research on
campus and to leverage our electronic medical record. This complements the remarkable basic science achievements
of the research faculty at UC San Diego. RCHSD is committed to providing the best of care for children through
research and clinical expertise.
Sincerely,
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Donald B. Kearns, MD
Kathleen A. Sellick
Herbert C. Kimmons, MD
Surgeon-In-Chief,
Rady Children’s Specialists of San Diego,
A Medical Foundation
President and CEO
Rady Children’s Hospital-San Diego
Executive Director,
Rady Children’s Specialists of San Diego,
A Medical Foundation
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Heart Institute
CARDIOLOGY
Rady Children’s Heart Institute was created to integrate and coordinate the clinical, research and educational programs of the
Cardiology and Cardiovascular Surgery Divisions at Rady Children’s Hospital-San Diego (RCHSD).
The Division of Cardiology currently includes 13 full time
cardiologists. Recruitments since July 2012 include: Dr. Fagan,
a general cardiologist who joined the Cardiology Division in
January 2013, Dr. Sun, an expert in fetal echo and imaging who
joined the Cardiology Division in August 2013, and Dr. Hedge,
an expert in cardiac MRI and imaging who joined the Cardiology Division in August 2013.
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FACULTY
John W. Moore, MD, MPH, Division
Chief, Professor of Clinical Pediatrics;
Medical Director of Division of
Cardiology, RCHSD; Medical
Director, Cardiac Catheterization
Laboratory, RCHSD
Christopher K. Davis, MD, PhD, Assistant
Clinical Professor of Pediatrics;
Medical Director of Exercise
Laboratory, RCHSD
Howaida G. EL-Said, MD, PhD, Associate
Professor of Pediatrics
Jeffrey R. Frazer, MD, Associate Clinical
Professor of Pediatrics
Raymond R. Fripp, MD, Clinical
Professor of Pediatrics; Medical
Director of Echocardiography
Laboratory, RCHSD
Paul D. Grossfeld, MD, Associate
Clinical Professor of Pediatrics;
Director of Pediatric Cardiology
Fellowship Program
Sanjeet Hegde, MD, HS Assistant
Clinical Professor
Stanley E. Kirkpatrick, MD, Associate
Clinical Professor of Pediatrics,
retired (volunteer faculty)
Delaram Molkara, MD, Assistant
Clinical Professor of Pediatrics
Vishal Nigam, MD, Assistant Professor
of Pediatrics in Residence
James C. Perry, MD, Clinical Professor
of Pediatrics; Medical Director of
Electrophysiology, Pacing and Adult
Congenital Heart Disease, RCHSD
Beth Printz, MD, Associate Professor of
Clinical Pediatrics; Medical Director
of Non-Invasive Cardiac Imaging,
RCHSD
Heather Sun, MD, HS Assistant Clinical
Professor
POSTDOCTORAL
FELLOWS
Mohammad Ebrahim, MD 1st year,
UCSD
Serena Sah, MD, 2nd year, UCSD
Gabrielle Vaughn, MD, 3rd year, UCSD
Juliana Gomez-Arostegui, MD,
3rd year, UCSD
Matthew Williams, MD, 3rd year, UCSD
Kiran Mallula, MD, 4th year Interventional Clinical Fellow, UCSD
Left to Right: Howaida El-Said,
Jeffrey Frazer, Beth Printz,
Sanjeet Hedge, James Perry
Heart Institute
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CLINICAL ACTIVITIES
INPATIENT/OUTPATIENT
The Cardiology Division is the only
comprehensive tertiary care provider of
cardiovascular services in the region (San
Diego, Imperial, and South Orange Counties), and it receives referrals from Balboa
Naval Medical Center, as well as the San
Diego Regional Kaiser Medical Center.
In addition, the Division is the major
off island referral center for the State of
Hawaii. The Division’s clinical volumes for
the academic year 2012-2013 were 12,085
total outpatient visits including 1397
patients seen in satellite offices. 697 catheterizations were performed, about 70%
4
of which were interventional catheterizations. The echocardiography laboratory
performed 9511 echocardiograms.
In the last five years there has been
steady growth in all categories. The
growth of the division clinical volumes
has been related both to expanding the
referral practice within Southern California and neighboring states, as well as
to meeting previously unmet demand for
services within the traditional referral
regions. The Division’s clinical volumes
place the program among the largest
pediatric and congenital heart disease
centers in the United States.
Left to Right: Brian Fagan,
Vishal Nigam, John Moore,
Heather Sun, Paul Grossfeld,
Delaram Molkara, Christopher
Davis, Raymond Fripp
Heart Institute
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RESEARCH ACTIVITIES
The Division’s basic and translational
research program is anchored by Dr. Paul
Grossfeld and Dr. Vishal Nigam.
Dr. Grossfeld investigates the genetic
basis of congenital heart defects and
Jacobsen’s Syndrome (11qdel).
His
additional projects include induced Pleuripotent Stem Cells to derive cardiac
lineages from human Jacobsen syndrome
patient fibroblasts (“Disease in a Dish”);
defining gene regulatory pathways
involving ETS-1 in cardiac neural crest
cell development, and pathways that suppress the development of heart defects;
and the genetic basis of cognitive and
behavioral defects in Jacobsen syndrome.
Dr. Nigam’s laboratory is focused on
investigating the molecular and genetic
mechanisms involved in aortic valve
stenosis and in valve calcification. In
addition, he is studying the role of biomechanical stretch on activation of
calcification pathways and the role of biomechanical stressors on cardiac defects,
and the mechanism of how stretch and
shear stress stimulate ventricular growth
in utero.
The Division’s faculty and fellows have
also been involved in a large number of clinical research projects. There are currently 31
active IRB approved clinical projects:
Christopher Davis, MD, PhD
Determining the Natural and “Unnatural”
history of Anomalous Aortic Origin of
a Coronary Artery with Interarterial
or Intraconal or Intramural Course
(AAOCA): Establishing a Multi-Institutional Registry
The Hybrid Procedure as an Alternative to the Norwood Sano in High
Risk Hypoplastic Left Heart (HLHS)
Patients (Retrospective Chart Review)
Howaida El-Said, MD, PhD
ADO II Clinical Study
Closure of Muscular Ventricular Septal
Defects with the AMPLATZER Muscular VSD Occluder–Post Approval Study
native to the Norwood Sano in High
Use of the Melody Transcatheter Pulmonary Valve Ensemble (Melody
TPV) as a Humanitarian Use Device
(HUD) under a Humanitarian Device
Exemption (HDE) HDE#: H080002
designated July 10, 2007 and approved
January 25, 2010–HUD #07-0810
The Damus-Kaye Stansel (DKS) Surgical
Procedure: Quality of Life After DKS
Continued Access to Covered Cheatham
Platinum Stent for Prevention or Treatment of Aortic Wall Injury Associated
with Aortic Coarctation (COAST
II CA)
Coarctation of the Aorta Stent Trial
(COAST ) Phase I
Implantation of the Medtronic Melody
Transcatheter Pulmonary Valve (TPV)
in Patients with Dysfunctional Right
Ventricular Outflow Tract (RVOT)
Conduits: A Post Market Approval
Study
Covered Cheatham-Platinum Stent for
Prevention or Treatment of Aortic
Wall Injuries Associated with Aortic
Coarctation (COAST II)
Procedure: Long-term Follow-up of Survivors and Analysis of Possible Sequelae
Congenital Cardiac Catheterization
Outcomes Project (C3PO) Protocol
Version 3–May 2009
Congenital Cardiac Catheterizations
Project on Outcomes (C3PO) Quality
Improvement Registry
Congenital Cardiac Catheterizations
Project on Outcomes (C3PO-QI) Quality Improvement–Radiation Project
Transcatheter Closure of Atrial Septal
Defect (ASD) using the Amplatzer
Septal Occluder with Transthoracic
Echocardiography or Transesophageal Echocardiography
Pulmonary Artery Repair with Covered
Stents (PARCS): The Use of Covered
Cheatham Platinum Stents for Repair
of RV to PA Conduits Disruption
During Preparation for Implantation
of the Melody Transcatheter Pulmonary Valve–Pending IRB Approval
Jeffrey Frazer, MD
Outcomes in Preterm and Low Birthweight
Newborns Undergoing Cardiac Surgery
Raymond Fripp, MD
Trial of Beta Blocker Therapy (Atenolol)
vs. Angiotensin II Receptor Blocker
Therapy (Losartan) in Individuals
with Marfan Syndrome. This study
is sponsored by the National Heart,
Lung & Blood Institute (NHLBI) of the
National Institutes of Health (NIH),
through the Pediatric Heart Network
(PHN). New England Research Institutes serves as the Data Coordinating
Center (DCC) for the PHN Network
under grant No. U01 HL68270, CFDA
# 93.837. IND#76,539
Paul Grossfeld, MD
Trial of Beta Blocker Therapy (Atenolol)
vs. Angiotensin II Receptor Blocker
Therapy (Losartan) in Individuals
with Marfan Syndrome. This study
is sponsored by the National Heart,
Lung & Blood Institute (NHLBI) of the
National Institutes of Health (NIH),
through the Pediatric Heart Network
(PHN). New England Research Institutes serves as the Data Coordinating
Center (DCC) for the PHN Network
under grant No. U01 HL68270, CFDA
# 93.837. IND#76,539
John W. Moore, MD, MPH
Pulmonary Artery Repair with Covered
Stents (PARCS): The Use of Covered
Cheatham Platinum Stents for Repair
of RV to PA Conduits Disruption
During Preparation for Implantation
of the Melody Transcatheter Pulmonary Valve–Pending Approval
Continued Access to Covered Cheatham
Platinum Stent for Prevention or Treatment of Aortic Wall Injury Associated
with Aortic Coarctation (COAST II
CA)
Coarctation of the Aorta Stent Trial
(COAST ) Phase I
Implantation of the Medtronic Melody
Transcatheter Pulmonary Valve (TPV)
in Patients with Dysfunctional Right
Ventricular Outflow Tract (RVOT) Conduits: A Post Market Approval Study
Covered Cheatham–Platinum Stent for
Prevention or Treatment of Aortic Wall
Injuries Associated with Aortic Coarctation (COAST II)
Heart Institute
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January 25, 2010–HUD #07-0810
Closure of Muscular Ventricular Septal
Defects with the AMPLATZER Muscular VSD Occluder–Post Approval Study
Transcatheter Closure of Atrial Septal
Defect (ASD) using the Amplatzer
Septal Occluder with Transthoracic
Echocardiography or Transesophageal
Echocardiography
Congenital Cardiac Catheterizations Project on Outcomes (C3PO-QI) Quality
Improvement Registry
Congenital Cardiac Catheterizations Project on Outcomes (C3PO-QI) Quality
Improvement–Radiation Project
The Hybrid Procedure as an Alternative to the Norwood Sano in High
Vishal Nigam, MD
MicroRNA Profiling in Neonates Undergoing Cardiopulmonary Bypass
Profiling of Tissues from Patients with
Congenital Heart Defects
Modeling Hemodynamic Stresses in
Congenital Heart Disease
Retrospective Profiling of Hypoplastic
Left Heart Ventricular Tissue
The Damus-Kaye Stansel (DKS) Surgical Procedure: Long-term Follow-up
of Survivors and Analysis of Possible
Sequelae
James Perry, MD
Transmural Atrial Leads in Adult
Congenital heart patients: Lead Performance in Long-Term Follow-Up
(Retrospective Chart Review)
SPKLS002: Echocardiographic Assessment of Cardiac Left Ventricular
Strain, Torsion and Blood Flow Analysis in Subjects with Congenital and
Acquired Heart Disease
6
A Retrospective Study of Children Presenting with Tachycardia-Mediated
Cardiomyopathy
Outcomes in Preterm and Low Birthweight
Newborns
Undergoing
Cardiac Surgery
Beth Printz, MD, PhD
SPKLS002: Echocardiographic Assessment of Cardiac Left Ventricular
Strain, Torsion and Blood Flow Analysis in Subjects with Congenital and
Acquired Heart Disease
Implantation of the Medtronic Melody Transcatheter Pulmonary Valve
(TPV) in Patients with Dysfunctional
Right Ventricular Outflow Tract
(RVOT) Conduits: A Post Market
Approval Study
January 25, 2010–HUD #07-0810
TEACHING ACTIVITIES
The Division provides a comprehensive accredited educational program for
fellowship training in pediatric cardiology. Dr. Grossfeld is the Fellowship
Program Director. Fellows are offered
clinical teaching and mentoring in all
aspects of clinical cardiology: Outpatient
care and evaluation, Inpatient and ICU
care Echocardiography, CT and MRI,
Diagnostic and Interventional Cardiac
Catheterization, Electro-physiology and
Pacing, Exercise Physiology and Clinical
Research. A broad schedule of lectures
and presentations are offered including:
Weekly Surgery Conference, Weekly
Catheterization Conference, Weekly
Core Lecture, and Monthly Journal Club
and Research Meeting. The three-year
program has full ACGME accreditation.
The Division offers a fourth year
position for an Advanced Fellow in interventional congenital cardiology. This
position includes training and experience as operator or first assistant in
approximately 200 procedures, teaching conferences, and training in clinical
research.
Faculty/staff cardiologists are also
active in training of pediatric residents
and medical students. Rotation in pediatric cardiology is not mandatory for
residents, but many selected the one
month Pediatric Cardiology elective
designed by Dr. Perry. This elective
provides both inpatient and outpatient
experiences.
Dr. Davis participates as an Instructor
in the “Clinics” course required for second year medical students.
AWARDS, HONORS, AND
MAJOR PRESENTATIONS
Christopher Davis, MD, PhD
Angadi SS, Weltman NT, Patrie JT, Barrett EJ, Weltman A, Brock DW, Irving
B, Davis CK, Rodriguez J, Gaesser
GA. Effects of a low-carbohydrate vs.
high-carbohydrate, high-fiber diet on
soluble cell adhesion molecules and
endothelial function in adults with
metabolic syndrome. Experimental
Biology Conference, April 2012
Howaida EL-Said, MD, PhD
Randomized trial of transthoracic echocardiography versus transesophageal
echocardiography for definitive assement and guidance of transcatheter
closure of ASDs in children using the
Ampaltzer Septal Occluder. Pediatric
Interventional Cardiac Symposium
(PICS), Boston, MA, July 2011
A risk stratified algorithm for eclectic use
of hybrid palliation in high risk neonates. PICS, Boston, MA, July 2011
Use of TPA for femoral artery obstruction
post catheterization. PICS, Boston,
MA, July 2011
First report of atretic coronary sinus
stenting resulting in dramatic
improvement of ventricular function
in functional single ventricle. PICS,
Boston, MA, July 2011
Fetal Echocardiography from the Sonographer to the Interventionalist.
Genetic Ultrasound, Basic Sonography and Hands-On Patient Scanning.
Schaetzel Center, San Diego, CA,
March 2012
Heart Institute
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Breaking the Limits-Extensibility of
Medium and Large Stents. Presented
in PICS, April 2012
Walking on Ice with the GUCH. Interventions for Adults with Congenital Heart
Disease. Invited speaker. Maui Cardiovascular Symposium, September 2012
Prospective Randomized Trial of
Trans-thoracic
Echocardiography
(TTE) vs. Trans-esophageal Echocardiography (TEE) for Definitive
Assessment and Guidance of Transcatheter Closure of Atrial Septal
Defects (ASD) in Children using the
Amplatzer Septal Occluder (ASO).
Oral presentation PICS, Miami, FL,
January 2013
Paul D. Grossfeld, MD
Oral presentation, New basic and genetic
insights into HLHS. American Heart
Association, Orlando, FL, November
2011
Update on genes causing cognitive and
behavioral disorders in 11q. Seventh
European 11q Research and Resource
Group meeting, Pforzheim, Germany,
November 2011
The role of ETS-1 in causing human congenital heart defects. Department of
Cardiology, University of Arizona
School of Medicine, March 2012
John W. Moore, MD, MPH
Invited Speaker, PICS–AICS, Stenting
Coarctation of the Aorta. Boston,
MA, July 23, 2011
Invited Speaker, Controversies in Pediatric Cardiology for the Primary Care
Professional. Small PDA’s & ASD’s: Do
They Need to be Closed? Orange, CA,
March 3, 2012
Invited Speaker, PDA in Children and
Adults. ACC.12, Chicago, IL, March
2012
Invited Speaker, IMPACT Registry. Children’s Hospital Association Meeting,
San Diego, CA, April 19, 2012
Invited Speaker, IMPACT Registry. Treatment of Coarctation in Adults. SCAI,
Las Vegas, NV, May 11, 2012
Invited Testimony before FDA Panel investigating ASD device safety representing
American College of Cardiology, Gaithersburg, MD, May 24, 2012
Invited Speaker, Coarctation: The Case
for Angioplasty and Stenting. North
American Society for Cardiovascular
Imaging, Pasadena, CA, October 15,
2012
Invited Speaker, Embolization Therapy
in Congenital Heart Disease. ACC 13,
March 9, 2013, San Francisco, CA
Moderated Abstract, IMPACT Registry:
First Review of Community Practice
with Respect to Device Closure of
ASD and PDA. ACC 13, San Francisco, CA, March 12, 2013
Invited Speaker, WSOPC, Melody Valve.
Monterey, CA, June 8, 2013
James Perry, MD
Device therapy in adult congenital heart
patients: saving lives? Prague Symposium on Congenital Heart Disease,
Prague, Czech Republic, December 2011
Adults with Congenital Heart Disease:
What Does Transition Look Like?
UCSD/Rady Children’s Grand Rounds,
San Diego, CA, December 2011
When is Primary Prevention ICD Therapy an Appropriate Consideration in
Adult CHD? Evolving Concepts in
CV Management Symposium, San
Diego, CA, January 2012
Pacemaker implantation in children and
adults with congenital heart disease.
Pacemaker and ICD therapy in complex congenital heart disease, State of
the Art Pediatric and CHD Electrophysiology. 4th Asia-Pacific Pediatric
Cardiology Society Symposium, Taipei, Taiwan, April 2012
Good Old Antiarrhythmic Therapy.
Heart Rhythm Society Annual Sessions, Boston, MA, May 2012
Beth Printz, MD, PhD
Invited Speaker, Conference on Sudden
Cardiac Arrest in Children, Anaheim,
CA (Non-invasive Imaging), 2011
MRI assessment of cardiac tumors. International Society for Cardiac MR,
January 2013
Friday AM Core Cardiology Lecture–
Pediatric Heart Network Review,
January 2013
Pediatric Residency Noon Conference
Lecture–Cardiac MRI and CT. April
2013
San Diego Society for Cardiac MRI Lecture–Case Presentation, June 2013
Heather Sun, MD
Sun HY, Punn R, Selamet Tierney ES,
Tacy TA. Stroke Volume is a More
Precise Measurement Than Cardiac
Output in the Assessment of Fetal
Ventricular Function. American Society of Echocardiography Scientific
Sessions, Poster Session. National
Harbor, MD, 2012
Sun HY, Behzadian F, Punn R, Tacy TA.
Progressive Deterioration in Left
Ventricular Deformation After Pulmonary Artery Band Training and
Subsequent Repair in Ventriculoarterial Discordance. American Heart
Association Scientific Sessions, Poster
Session, Orlando, FL, 2011
Pediatric Resident Board Review, Cyanotic
Congenital Heart Disease. Lucile Packard Children’s Hospital, August, 2012
Echocardiography Laboratory Teaching
Conference, Single Ventricle Reconstruction Trial Highlights, Fetal
Cardiac Interventions, Measures of
RV Function, Neurodevelopmental Outcomes in Congenital Heart
Disease. Lucile Packard Children’s
Hospital, 2012/2013
PUBLICATIONS
Bergersen L, Gauvreau K, Marshall A,
Kreutzer J, Beekman R, Hirsch R,
Foerster S, Balzer D, Vincent J, Hellenbrand W, Holzer R, Cheatham
J, Moore J, Lock J, Jenkins K. Procedure–Type Risk Categories for
Pediatric and Congenital Cardiac
Catheterization.
Circ Cardiovasc
Interv, 4:188-94, 2011.
Davis CK, Pastuszko P, Lamberti J, Moore
J, Hanley F, El Said H. The hybrid
procedure for the border line left ventricle. Cardiol Young, 21:26-30, 2011.
EL-Said H, Hamzeh R, Lamberti J, Moore
JW. Catheter Balloon Adjustment of
the Pulmonary Artery Band: Feasibility and Safety. Pediatr Cardiol,
32:8-13, 2011.
Margossian R, Lu M, Minich LL, Bradley
TJ, Cohen MS, Li JS, Printz BF, Shirali
GS, Sleeper LA, Newburger JW, Colan
SD. Predictors of coronary artery
Heart Institute
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visualization in Kawasaki disease. J
Am Soc Echocardiogr, 24:53-9, 2011.
Molkara D, Tejman-Yarden S, EL-Said
H, Moore JW. Pericardiocentesis of
Noncircumferential Effusions Using
Nonstandard catheter Entry Sites
guided by Echocardiography and
Fluoroscopy. Congenit Heart Dis,
6:461-465, 2011.
Sheperd S, S Tejman-Yarden, S Khanna,
CK Davis, A Batra. Dexmedetomidine-related atrial standstill and loss
of capture in a pediatric patient after
congenital heart surgery. Critical Care
Medicine, 39(1):187-9, 2011.
Sleeper LA, Minich LL, McCrindle BM,
Li JS, Mason W, Colan SD, Atz AM,
Printz BF, Baker A, Vetter VL, Newburger JW; Pediatric Heart Network
Investigators. Evaluation of Kawasaki Disease Risk-Scoring Systems
for Intravenous Immunoglobulin
Resistance. Sleeper LA, Minich LL,
McCrindle BM, Li JS, Mason W,
Colan SD, Atz AM, Printz BF, Baker
A, Vetter VL, Newburger JW; Pediatric Heart Network Investigators. J
Pediatr, 158(5):831-835.e3, 2011.
Moore J. Chest pain. In: Textbook of
Clinical Pediatrics, Edited by Springer-Verlag, Berlin, 2011.
Moore JW. Transcatheter valve technology: A game changer! J Am College
Cardiol, 58:123-4, 2011.
Pierce J, Sharma S, Hunter C, Bhombal
S, Fagan B, Corchado Y, Grikscheit T,
Bushman G. Intraoperative Hypercyanosis in a Patient with Pulmonary
Artery Band: Case Report and Review
of the Literature. Children’s Hospital
Los Angeles. Anesthesia & Analgesia.
(accepted for publication – June 2011).
Molkara D, Tejman-Yarden S, El-Said
H, Moore JW. Pericardiocentesis of
noncircumferential effusions using
nonstandard catheter entry sites
guided by echocardiography and
fluoroscopy. Congenit Heart Dis,
6(5):461-5, 2011.
Backes CH, Cua C, Kreutzer J, Armsby L,
EL-Said, H, Moore JW, Gauvreau K,
Bergersen L, Holzer R. Low weight as
an independent risk factor for adverse
8
events during cardiac catheterization
of infants. Catheter Cardiovasc Interv,
2012, epublished.
Davis CK, P Pastuszko, J Lamberti, J
Moore, F Hanley, H El Said. The
Hybrid Procedure for the Borderline Left Ventricle. Cardiology in the
Young, 21(1):26-30, 2011.
Bashore T, Balter S, Barac A, Byrne J,
Cavendish J, Chambers C, Laskey W,
Miller J, Moliterno D, Moore J, Oliver-McNeil S, Popma J, Tommaso
C. American College of Cardiology
Foundation/Society for Cardiovascular Angiography and Interventions
Clinical Expert Consensus Document on Cardiac Catheterization
Laboratory Standards Update. J Am
College Cardiol, 2012; 59:2221-2305
and Catheter Cardiovasc Interv, 2012;
80:E37-49.
Bratincsak A, EL-Said HG, Moore JW.
Low Dose Tissue Plasminogen Activator Treatment for Vascular Thrombosis
following Cardiac Catheterization in
Children: A Single Center Experience.
Catheter Cardiovasc Interv, 2012; epublished.
Bratincsak A, Salkini A, EL-Said H,
Moore JW. Percutaneous stent
implantation into coronary arteries in
infants. Catheter Cardiovasc Interven,
79:303-11, 2012.
EL-Said HG, Bratinshak A, Gordon,
BM Moore JW. Closure of Perimembranous Ventricular Septal Defects
with Aneurysmal Tissue Using the
Amplatzer Duct Occluder I: Lessons
Learned and Medium Term Follow Up.
Catheter Cardiovasc Interven, 80:895903, 2012.
Perry JC, Landzberg M, Franklin W,
Webb G, Chang AC. Cardiac intensive care of the adult with congenital
heart disease: basic principles in the
management of common problems.
Pediatr Cardiol, 33:484-90, 2012.
Cohen, MI, Triedman JK, Cannon BC,
Davis AM, Drago F, Janousek, J,
Klein GJ, Law IH, Morady FJ, Paul
T, Perry JC, Sanatani, S, Tanel RE.
A PACES/HRS Expert Consensus
Statement on the Management of the
Asymptomatic Young Patient with
a Wolff-Parkinson-White (WPW)
Electrocardiographic Pattern. Heart
Rhythm, 6:1006-24, 2012.
El-Said HG, Bratincsák A, Salkini, Moore
JW. Percutaneous stent implantation into coronary arteries in infants.
Catheter Cardiovasc Interv, 79(2):30311, 2012.
Rao RP, Connolly D, Lamberti JJ, Fripp
R, El Said H. Transverse aortic arch
to descending aorta ratio: a new
echocardiographic parameter for
management of coarctation of the
aorta in the infant. Congenit Heart
Dis, 7(2):160-9, 2012.
Bratincsák A, El-Said HG, Moore JW.
Low dose tissue plasminogen activator treatment for vascular thrombosis
following cardiac catheterization in
children -a single center experience.
Catheter Cardiovasc Interv, 2012 Jun.
Perry JC. Pediatric and Adult Congenital Heart Disease Standards. HRS
Expert Consensus Statement: EP Lab
Standards: Ergonomics, Equipment,
Personnel, Policy and Safety; Heart
Rhythm, 2012; epub August 2012.
Takao CM, El Said H, Connolly D,
Hamzeh RK, Ing FF. Impact of stent
implantation on pulmonary artery
growth. Catheter Cardiovasc Interv,
2012 Oct 16.
El Said HG, Bratincsak A, Gordon BM,
Moore JW. Closure of perimembranous ventricular septal defects with
aneurysmal tissue using the Amplazter Duct Occluder I: lessons learned
and medium term follow up. Catheter
Cardiovasc Interv, 2012 Nov.
Hollander SA, Bernstein D, Yeh J, Dao D,
Sun HY, Rosenthal D. Outcomes of
Children Following a First Hospitalization for Dilated Cardiomyopathy.
Circ Heart Failure, 5(4): 437-43, 2012.
Zhang Y, Liang X, Ma J, Jing Y, Gonzales
MJ, Villongco C, Krishnamurthy A,
Frank LR, Nigam V, Stark P, Narayan
SM, McCulloch AD. (2012) An Atlasbased Geometry Pipeline for Cardiac
Hermite Model Construction and Diffusion Tensor Reorientation. Medical
Image Analysis, 2012; PMID 22841777.
Heart Institute
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Moore J, Hegde S, EL-Said H. et al. Transcatheter Device Closure of Atrial
Septal Defects: A Safety Review. J Am
Coll Cardiol Intv, 6:433-4442, 2013.
Lin C, Hegde S, Marshall A, Porras D,
Gauvreau K, Balzer D, Beekman R,
Torres A, Vincent J, Moore, J, Holzer
R, Armsby L, Bergersen L. Incidence
and Management of Life-Threatening
Adverse Events During Cardiac Catheterization for Congenital Heart Disease.
Pediatr Cardiol, 2013; epublished.
Holzer RJ, Geuvreau K, Kreutzer J,
Moore JW,McElhinney DB, Bergersen
L. Relationship between procedural
adverse events associated with cardiac
catheterization for congenital heart
disease and operator factors: Results
of a multi- institutional registry
(C3PO). Catheter Cardiovasc Interv,
2013; epublished.
Learn CP, Holzer RJ, Daniels CJ, Torres
AJ, Vincent JA, Moore JW, Armsby
LB, Landzberg MJ, Bergersen L.
Adverse events rates and risk factors
in adults undergoing cardiac catheterization at pediatric hospitals—results
from the C3PO. Catheter Cardiovasc
Interv, 81:997-1005, 2013.
Truong UT, Sun HY, Tacy TA. Myocardial
Deformation in the Fetal Single Ventricle. J Am Soc Echocardiogr, 26(1):
57-63, 2013.
Backes CH, Cua C, Kreutzer J, Armsby
L, El-Said H, Moore JW, Gauvreau
K,Bergersen L, Holzer RJ. Low
weight as an independent risk factor for adverse events during cardiac
catheterization of infants. Catheter
Cardiovasc Interv, 2013 Feb 22.
Kunder R, Kunder C, Sun HY, Berry G,
Messner AH, Frankovich J, Roth S,
Mark J. Pediatric Plastic Bronchitis:
Case Report and Retrospective Comparative Analysis of Epidemiology
and Pathology. Case Reports in Pulmonology, Epub 2013 Apr 11.
Sun HY, Buccola KJ, Punn R, Silverman
NH, Peng L, Perry SB, Balasubramanian S. Transcatheter Device Closure
of a Congenital Aortic-Left Atrial
Tunnel. Congenital Heart Dis, 2013
Apr 22. Epub ahead of print.
EL-Said H, Hegde S, Moore J. First report
of atretic coronary sinus stenting in
a 5-Kg infant resulting in dramatic
improvement of ventricular function
in functional single ventricle. Congenit Heart Dis, 2013; epublished.
Selamet Tierney ES, Levine JC, Chen S,
Bradley TJ, Pearson GD, Colan SD,
Sleeper LA, Campbell MJ, Cohen MS,
De Backer J, Guey LT, Heydarian H,
Lai WW, Lewin MB, Marcus E, Mart
CR, Pignatelli RH, Printz BF, Sharkey
AM, Shirali GS, Srivastava S, Lacro RV;
Pediatric Heart Network Investigators.
Echocardiographic methods, quality
review, and measurement accuracy in
a randomized multicenter clinical trial
of marfan syndrome. J Am Soc Echocardiogr, 26(6):657-66, 2013.
Molkara D, Tejman-Yarden S, EL-Said
H, Moore J. Periocardiocentesis of
non-circumferential effusions using
non-standard catheter entry sites
guided by echocardiography and fluoroscopy. Congenit Heart Dis (in press).
EL-Said H, Hegde S, Moore JW. First
report of atretic coronary sinus stenting resulting in dramatic improvement
of ventricular function in functional
single ventricle. Submitted to Congenital heart disease. Congenital Heart
Disease April 2013 (accepted).
Peng DM, Sun HY, Hanley FL, Olson I,
Punn R. Coronary Sinus Obstruction
After Atrioventricular Canal Defect
Repair. Congenital Heart Dis, 2013
May 20. Epub ahead of print.
Sun HY, Boe J, Barth R, Tacy TA. Fetal
MRI Correlates with Postnatal CT
Angiogram Assessment of Pulmonary
Anatomy in Prenatally Diagnosed
Tetralogy of Fallot with Absent Pulmonary Valve. Congenital Heart Dis,
2013 May 22. Epub ahead of print.
Sun HY, Behzadian F, Punn R, Tacy TA.
Decremental left ventricular deformation after pulmonary artery band
training and subsequent repair in ventriculoarterial discordance. J Am Soc
Echocardiogr, 26(7):765-74, 2013.
Longmuir P, Brothers J, de Ferranti S,
Hayman L, Van Hare G, Matherne P,
Davis C, Joy E, McCrindle B. Promo-
tion of Physical Activity for Children
and Adults with Congenital Heart
Disease: A Scientific Statement from
the Atherosclerosis, Hypertension,
and Obesity in Youth Committee,
Council on Cardiovascular Diseases
in the Young, American Heart Association. Circulation, 2013, 217.
Tedjasaputra V, Carlos Sá R, Arai TJ,
Holverda S, Theilmann RJ, Chen
WT, Wagner PD, Davis CK, Prisk
GK, Hopkins SR. The heterogeneity of regional specific ventilation is
unchanged following heavy exercise
in athletes. Journal of Applied Physiology, July 2013, 115(1).
Nigam V, Srivastava D. Notch 1 represses
a default osteogenic pathway in aortic
valve mesenchymal cells. JMCC (in
press).
Szeto K, Pastuszko P, del Alamo JC, Lasheras JC, Nigam V. Bicuspid Aortic
Valves Experience Increased Strain As
Compared To Tricuspid Aortic Valves.
World Journal for Pediatric and Congenital Heart Surgery, 2013. In press,
DOI: 10.1177/2150135113501901.
Heart Institute
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CARDIOTHORACIC SURGERY
The Pediatric Cardiac Surgery Division of the Division of Cardiothoracic
Surgery at the UC San Diego (UCSD) School of Medicine is based at Rady
Children’s Hospital-San Diego (RCHSD). The Division, in conjunction with
the Division of Pediatric Cardiology, provides cardiovascular surgery services
for infants, children and adults with congenital and acquired heart disease.
The Division serves the San Diego metropolitan area (population: 3.2 million)
and it is a major referral center for Imperial and Orange Counties, Hawaii,
New Mexico, Mexico, and the Pacific Rim Islands. Dr. John J. Lamberti is the
Joyce and Eugene Klein Director of the Heart Institute at RCHSD and he is
Division Chief of Cardiovascular Surgery at RCHSD. Dr. Eric Devaney joined
the division on April 1, 2012. Dr. Devaney is an Associate Professor of Surgery
at UCSD and he is the Director of Cardiac Transplantation and Cardiac Assist
Devices at RCHSD. Dr. Devaney has also assumed the role of Medical
Director of Pediatric Cardiac Surgery Critical Care at RCHSD.
The Division’s clinical volume for the academic years 20112013 remained steady when compared to previous academic years.
The complexity of the caseload has increased due to increasing
referrals from outlying areas in Southern California and the State
of Hawaii. RCHSD is a “high volume” pediatric cardiac surgical
program according to the Society of Thoracic Surgeons (STS)
Congenital Heart Surgery Database. The Division’s outcomes
are comparable with other leading high volume centers. The STS
analysis is based upon risk-adjusted data. The complexity score for
RCHSD is slightly higher than the national average reflecting our
role as a major referral center.
FACULTY
John J. Lamberti, MD, Professor of
Surgery, Chief of Cardiac Surgery at
RCHSD Eugene and Joyce Klein
Director of the RCHSD Heart Institute
Eric J. Devaney, MD, Associate Professor of Surgery Director of Cardiac
Transplantation and Assist Devices at
RCHSDDirector of Pediatric Cardiac
Surgical Critical Care at RCHSD
Peter Pastuszko, MD, Associate
Clinical Professor of Surgery
(resigned eff. 4/8/2013)
1/23/14 4:37 PM
POSTDOCTORAL
FELLOWS
CLINICAL ACTIVITIES
Seemal Mumtaz, MD 2011-2013
The Division of Cardiothoracic Surgery
receives referrals from San Diego, Orange and Imperial counties; the Naval
Medical Center, San Diego; the San Diego
Regional Kaiser Medical Center; Tripler
Army Medical Center, Honolulu, Hawaii;
Kapiolani Medical Center for Women
and Children, Honolulu, Hawaii; Straub
Clinic, Honolulu, Hawaii and the Kaiser
Permanente Medical Group, Honolulu,
Hawaii. The Division’s clinical volume
for the academic years 2011-2013 included 514 open-heart, 137 closed-heart and
229 miscellaneous cardiovascular surgical
procedures. The faculty provides consultative services at UCSD Medical Center,
RCHSD, Sharp Mary Birch Hospital and
at all referral sites in Hawaii. In addition,
faculty members provide varying levels of
support for adult patients with congenital
heart disease undergoing treatment at all
of the adult hospitals in San Diego County.
Dr. John Lamberti and Dr. John
Moore organized and coordinated a three
day symposium in January 2012. The
symposium was entitled “Evolving Concepts in the Management of Complex
Congenital Heart Disease III”. The symposium represented the third in a series
of biennial meetings designed to address
the management of the most complex
forms of congenital heart disease. The
faculty consisted of multiple experts in
surgery and cardiology drawn from the
finest programs in North America.
RESEARCH ACTIVITIES
John J. Lamberti, MD: The Division par-
ticipates in multiple longitudinal studies
of congenital heart disease sponsored by
the Congenital Heart Surgeon’s Society.
Dr. Lamberti is the principal investigator
on multiple clinical protocols involving
complex congenital heart defects. The
studies are designed to evaluate the natural history, including before and after surgical therapy, of relatively rare congenital
heart defects in a multi-center collaborative effort.
Left to Right:
John Lamberti,
Eric Devaney
Heart Institute
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1/27/14 10:45 AM
MAJOR
GOALS &
PLANS
The RCHSD and UCSD Pediatric Cardiology and Cardiovascular Surgery programs
are committed to fulfilling our mission to
provide optimal care for infants, children
and adults born with Congenital Heart
Defects and to advance our knowledge and
understanding of Congenital Heart Disease.
To implement our strategic plan for Cardiac
Services we have:
1. successfully completed the recruitment of a third pediatric cardiothoracic
surgeon, who is expected to begin
operating on site in November 2013. We
have recently added additional cardiology faculty with strong expertise in fetal
echo and cardiac MRI.
2. funding for and are in the process of
physician recruitment for leadership
positions in Cardiac Transplantation
and Cardiac Critical Care.
3. completed the installation of and are
currently actively using a dedicated
pediatric Cardiac MRI Scanner and a
new state of the art dedicated Pediatric
Cardiac Catheterization Laboratory. We
are also working in our new cardiac
operating room. We have opened a dedicated Cardiovascular Intensive Care
Unit (CVICU), and we are on the verge
of moving into an expanded,
new Heart Center.
4. administrative and Board of Directors approval in place to establish an
in-house pediatric heart transplant
program associated with the UCSD
adult program. We are in process of
submitting our UNOS application for
cardiac transplantation with the long
range goal of adding a program in
lung transplantation.
1/23/14 4:37 PM
Eric J. Devaney, MD: Dr. Devaney has
a strong interest in basic science, clinical
research and cardiac transplantation. Dr.
Devaney has been instrumental in the
creation of a cardiovascular ICU (CVICU) at RCHSD. Dr. Devaney is responsible for the recruitment of personnel
and the creation of the infrastructure
that will permit RCHSD to begin cardiac
transplantation in 2014. Dr. Devaney is a
member of the RCHSD Research Council.
Basic Science Focus:
1. Sarcomeric basis of contractile dysfunction in heart failure and cardiomyopathy
2. Genetic modification of motor proteins in normal and failing myocytes
3. Analysis of thin filament maintenance in cardiac myocytes
Clinical Focus:
1. Clinical applications of assist devices in pediatric heart failure
2. Clinical outcomes in pediatric cardiac surgery
Dr. Peter Pastuszko: Dr. Pastuszko is the
primary cardiac surgeon involved in
an ongoing series of research projects
at the University of Pennsylvania in
Philadelphia, PA. Dr. Pastuszko travels to Philadelphia five times a year
for an intense schedule of experiments
designed to evaluate the effects of cardiopulmonary bypass on brain structure and function in a neonatal piglet
model. In addition, Dr. Pastuszko collaborated with Dr. Vishal Nigam from
the Division of Cardiology on several
projects (see publications).
DIVISIONAL FACULTY
TEACHING ACTIVITIES
The cardiac surgeons participate in the
following teaching activities:
• Dailymorningandafternoonrounds
at RCHSD with cardiac surgery fellows, cardiology fellows, ICU fellows,
nurses, nurse practitioners, nurses in
training, medical students, pediatric
residents and cardiology attendings
• Biweekly teaching rounds with the
PICU team and monthly teaching
conferences with the NICU team
• Conferences at RCHSD and UCSD
Medical Centers including the transplantation conference, adult cardiolo-
gy/cardiothoracic surgery conference,
pediatric cardiology/cardiothoracic
surgery conference and cardiothoracic
surgery resident teaching conference
• Cardiothoracicsurgeryoutpatientand
the Transplant clinics at UCSD and
RCHSD
• Medical student rotations in CT surgery and Clinical Anatomy. Dr. Lamberti is the mentor, consultant and
advisor to the congenital heart surgery
program at Kapiolani Medical Center
for Women and Children (KMCWC)
in Honolulu, Hawaii. KMCWC is the
primary pediatric teaching hospital of
the John A. Burns School of Medicine
Department of Pediatrics at The University of Hawaii/Manoa. Since 1994,
Dr. Lamberti has spent five weeks
each year at KMCWC assisting in surgery, participating in pre and postoperative care and overseeing quality assurance aspects of the cardiac surgery
program. Dr. Lamberti makes teaching rounds every morning during
Hawaii Heart Week. He also chairs
the peer review committee meeting at
KMCWC, and participates in the case
review conferences.
• Dr. Devaney leads a surgical team
on an annual humanitarian teaching
mission to Arturo Grullon Children’s
Hospital, Santiago, Dominican Republic and Bloom Hospital, San Salvador, El Salvador.
AWARDS, HONORS, AND
MAJOR PRESENTATIONS
John J. Lamberti, MD
Castle Connolly, America’s Top Doctors,
2009-2013 San Diego Union Tribune:
san Diego Super Doctors 2011-2012
Keynote Speaker, Pediatric cardiac surgery in 2012. Scripps Ranch Auxiliary
Event; “Raising the Bar,” Poway, CA,
October 12, 2011
Invited Lecture, RCHSD Foundation
“The WPO Experience,” two lectures
on heart surgery to community leaders. RCHSD ACP Conf. Rm, November 8, 2011
Co-Director of Evolving Concepts in the
Management of Complex Congenital
Heart Disease III. A Sympsium sponsored by RCHSD, January 19-21, 2012
Invited Presentation, Dilatation of the
Aortic Root after Repair of Conotruncal Defects
Invited Presentation, Heart Surgery in
2012 at RCHSD. RCHSD Auxiliary
Annual Educational Meeting, January
2, 2012
Invited Speaker, Pediatric Cardiac Transplantation. Senior Jurassic Medical Society Meeting at RCHSD, March 1, 2012
Lecturer, RCHSD Cardiac Clinical Nursing Council. Protein Losing Enteropathy, April 13, 2012
Lecturer, Cardiology Core Lecture series (Fellows Conference) at RCHSD.
Management of Single Ventricles,
May 25, 2012
Invited Debater, Con- The Ross Operation is Better than a Mechanical Valve.
Western Society of Pediatric Cardiology, Skamania Lodge, Stevenson, WA,
June 8-10, 2012
Keynote Speaker, Pediatric cardiac surgery in 2012. 2nd Annual New Way
Golf tournament, the Crosby at Rancho Santa Fe, July 24, 2012
Invited Speaker, North American Society
for Cardiovascular Imaging, Pasadena, CA, October 15, 2012
Keynote Address, Surgical Management
of Left Ventricular Outflow tract Obstructions
Mini debate, Coarctation: The Case for
Surgery
Visiting Professor, Division of Pediatric
Cardiovascular Surgery at The Cardinal Glennon Hospital of St. Louis
University, St. Louis, MO. The George
Kaiser Lecturer, Pediatric cardiac surgery in 2013, December 4-5, 2012
Participant, Bridgepoint Holiday Bowl
Halftime show Celebrating Rady Children’s Hospital, December 27, 2012
Visiting Professor, Divisions of Pediatric Cardiology and Pediatric Cardiac
Surgery at the University of Rochester,
Rochester, NY, May 29-30, 2013
Invited Lecturer, Future Treatment of
Complex Congenital Heart Disease,
National Meeting of the Mended Little
Hearts Group, Marriott Hotel, Mission
Valley, San Diego, CA, June 8, 2013
Keynote Speaker, Pediatric Cardiac Surgery Update. Miracle Mile of Quarters- Kiwanis Club, San Diego, CA,
June 12, 2013
Heart Institute
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1/23/14 4:37 PM
Research Support
Grant/Contract
Grant/Contract
# #
Annual Budget
Paul David Grossfeld, MD
Marfan Trial
NHBLI/National Marfan Foundation
$50,000 per year
Feb. 2009-Feb. 2014
Children’s Heart Foundation
$75,000 per year
Jan. 2011-Dec. 2013
Identification of Genes for Cognition in Distal 11q: Further Genotyping
2009-PEDGENO
$75,000
June 2009-Dec. 2009
Vishal Nigam, MD
Mechanisms Of Notch1 In Aortic Valve Calcification
Nih/Nhlbi/7 K08hl086775-03
$85,000
Oct. 2009-Apr. 2012
AGA Medical Corporation
$432,567
Dec. 2008-Indefinite
John Moore, MD
STARFlex in Atrial Septal Defect- Long term Status Assessment of Patients
Following Closure of ASD with the STARFlex Septal Occlusion System in IDE Study
G-960098 (SALSA)/NMT MEDICAL, INC.
$2,900
Aug. 2007-Indefinite
Coarctation of the Aorta Trail (COAST)
Johns Hopkins University
$198,865
Sept. 2007-Indefinite
Closure of Muscular Ventricular Septal Defects with the Amplatzer Muscular VSD
Occluder-Post Approval Study (Muscular VPA)
AGA Medical Corporation
$26,600
Sept. 2008-Indefinite
Eric Devaney, MD
NIH K08 Mentored Scientist Award
$620,000
2009-2014
Invited Discussant, Western Thoracic Surgical Association 39th Annual meeting, Coeur d’Alene, ID, June
26-29, 2013. Oral presentation #12:
Transposition of the Great Arteries
and Intact Ventricular Septum-Outcomes and Time Interval of Early
Repair. Authors: Woods RK, Trapp
K, Simpson PM, Cao Y, Ghanayem
NS, Twedell JS, from Milwaukee Children’s Hospital
Invited Speaker, The CVICU. 2014 Charity Ball Committee Meeting, RCHSD,
MOB 113, September 18, 2013
14
Total DirectTotal
Dollars/
Direct Dollars
Duration ofDuration
Grant of Grant
Eric J. Devaney, MD
Results of Second Stage Palliation of
Single Ventricle Heart Disease. 39th
Annual ODICH Society Conference,
Cleveland, OH, May 13-14, 2011
Cardiac Surgical Management of the
LowBirth Weight Infant. Evolving
Concepts in the Management of Complex Congenital Heart Disease, San
Diego, CA, January 19-21, 2012
PUBLICATIONS
Dr. Lamberti’s Publications
Colasacco C, Peterson BP, Worthen M,
Lamberti JJ and Spear R. Near infrared
spectroscopy (NIRS) to predict post-operative renal insufficiency following repair of congenital heart disease. World
Journal for Pediatric and Congenital
Heart Surgery, 2(4): 536-540, 2011.
Davis CD, Pastuszko PP, Lamberti JJ,
Moore JM, Hanley FL and EL-Said H.
The hybrid procedure for the borderline left ventricle. Cardiol Young, 21:2630, 2011.
Heart Institute
1/23/14 4:37 PM
ars
t
EL-Said H, Hamzeh R, Lamberti J, Moore J.
Catheter balloon adjustment of the pulmonary artery band: Feasibility and safety. Pediatr Cardiol, 32:8-16, 2011.
Punn R, Lamberti JJ, Balise RR and Seslar SP. QTc prolongation in pediatric
patients following congenital heart
disease surgery. Cardiol Young, 21:400410, 2011.
Tabbutt S, Jacobs M, Ohye RG, Goldberg C,
Morell VO, Hanley FL, Lamberti JJ and
Jacobs JP. Can randomized clinical trials
impact the surgical approach for hypoplastic left heart syndrome? World Journal for Pediatric and Congenital Heart
Surgery, July 2011 vol. 2, no. 3, 445-456.
Hannan EL, Cozzens KS, Samadashvili
JN, Morley JN, Williams RG, Kulik
TJ, Bierman FZ, Ruiz CE, Alfieris
GM, Lamberti JJ Jr., Gold JP. Regulatory efforts to assess and improve the
quality of pediatric cardiac surgery in
New York State. Progress in Pediatric
Cardiology, 32;(2): 111-119, 2011.
Rao RP, Connolly D, Lamberti JJ, Fripp
R, El Said H. Transverse Aortic Arch
to Descending Aorta Ratio: A New
Echocardiographic Parameter for
Management of Coarctation of the
Aorta in the Newborn. Congenital
Heart Disease, 7(2): 160-169, 2012.
Book Chapters
Pastuszko P, Lamberti J. Coarctation. In:
Cardiothoracic Surgery Review. Kenneth L. Franco and Vinod H Thourani, Editors. 2011 Lippincott Williams
and Wilkins, pp. 1588-1592.
Mainwaring RD, Lamberti JJ. Congenital
anomalies of the Mitral Valve. Pediatric Cardiac Surgery, Fourth Edition
(Editors: C.E. Mavroudis and C. Backer) 2013 John Wiley &Sons/Blackwell,
Hoboken, NJ, pp. 640-658.
Brief Publications
Lamberti JJ. Invited Editorial. In: J. Am.
Coll. Card. Aortic arch obstruction
after the Norwood procedure for hypoplastic left heart syndrome: Is is
inevitable? Is it preventable? JACC,
58:877-879, 2011.
Dr. Pastuszko’s Publications
Mammen A, Kubin J, Greeley WJ, Schears
GJ, Pastuszko P, Wilson DF and Pastuszko A. Effect of hypoxia on expression of selected proteins involved in
regulation of apoptotic activity in sriatum of newborn piglets. Neurochem
Res, 36:746-53, 2011.
Pirzadeh A, Schears G, Pastuszko P, Liu
H, Kubin J, Reade E, Mendoza-Paredes A, Greeley W, Nadkarni V, Wilson
DF, Pastuszko A. Effect of deep hypothermic circulatory arrest followed
by cardiopulmonary bypass on brain
metabolism in newborn piglets: Comparison of pH-stat and Alpha-stat
management. Pediatr Crit Care Med,
12(2):e79-86, 2011.
Davis CK, Pastuszko P, Lamberti JJ,
Moore J, Hanley F, El Said H. The hybrid procedure for the borderline left
ventricle. Cardiology in the Young, 21,
pp. 26-30, 2011.
Pastuszko P, Schears GJ, Pirzadeh A,
Kubin J, Greeley WJ, Wilson DF, Pastuszko A. Effect of Granulocyte-Colony Stimulating Factor on Expression
of Selected Proteins Involved in Regulation of Apoptosis in the Brain of
Newborn Piglets after Cardiopulmonary Bypass and Deep Hypothermic
Circulatory Arrest. J Thorac Cardiovasc Surg, 143, pp. 1436-1442, 2012.
Dr. Devaney’s Publications
Morales DL, Almond CS, Jaquiss RD,
Rosenthal DN, Naftel DC, Massicotte
MP, Humpl T, Turrentine MW, Tweddell JS, Cohen GA, Kroslowitz R, Devaney EJ, Canter CE, Fynn-Thompson
F, Reinhartz O, Imamura M, Ghanayem NS, Buchholz H, Furness S,
Mazor R, Gandhi SK, Fraser CD, Jr.
Bridging children of all sizes to cardiac transplantation: the initial multicenter North American experience
with the Berlin Heart EXCOR ventricular assist device. J Heart Lung Transplant. 30(1):1-8, 2011.
Hoashi T, Bove EL, Devaney EJ, Hirsch
JC, Ohye RG. Outcomes of 1(1/2)or 2-ventricle conversion for patients
initially treated with single-ventricle
palliation. J Thorac Cardiovasc Surg.
141(2):419-424, 2011.
Hoashi T, Bove EL, Devaney EJ, Hirsch
JC, Ohye RG. Intermediate-term clinical outcomes of primary biventricular repair for left ventricular outflow
tract obstruction and ventricular septal defect. J Thorac Cardiovasc Surg.
141(1):200-206, 2011.
Dinh, DC, Gurney, JG, Donohue, JE,
Bove, EL, Hirsch, JC, Devaney, EJ,
Ohye, RG. Tricuspid valve repair in
hypoplastic left heart syndrome. Pediatr Cardiol, 32(5):599-606, 2011.
Lee TM, Aiyagari R, Hirsch JC, Ohye
RG, Bove EL, Devaney EJ. Risk factor
analysis for second stage palliation of
single ventricle anatomy. Ann Thorac
Surg, 93(2):614-9, 2012.
Fraser CS, Jaquiss RD, Rosenthal DN,
Humpl T, Canter CE, Blackstone EH,
Naftel DC, Ichord RN, Bomgaars L,
Twedell JS, Massicotte MP, Turrentine
MW, Cohen GA, Devaney EJ, Pearce
FB, Carberry KE, Kroslowitz, R, Almond CS. Prospective trial of a pediatric ventricular assist device. N Engl J
Med, 367(6):532-41, 2012.
Kavarana MN, Riley M, Sood V, Ohye
RG, Devaney EJ, Bove EL, Hirsch JC.
Extended single-patch repair of supravalvar aortic stenosis: a simple and
effective technique. Ann Thorac Surg.
93(4):1274-8, 2012.
Book Chapters
Devaney EJ, Bove EL. Congenitally Corrected Transposition of the Great Arteries. In: Mavroudis C and Backer
CL, eds. Pediatric Cardiac Surgery, 4th
edition. West Sussex, Wiley Blackwell,
2013: 530-541.
Hirsch JC, Devaney EJ, Ohye RG, Bove
EL: Hypoplastic Left Heart Syndrome.
In: Mavroudis C and Backer CL, eds.
Pediatric Cardiac Surgery, 4th edition.
West Sussex, Wiley Blackwell, 2013:
619-635.
Heart Institute
15
1/23/14 4:37 PM
Maternal Fetal
Medicine
Physicians of the Maternal-Fetal Medicine Division of Rady
Children’s Specialists of San Diego (RCSSD) have been
providing prenatal diagnosis, ultrasound imaging,
consultation, and pregnancy care to families and physicians
in San Diego, Imperial, and Riverside Counties since 1990.
The Division continues to focus on:
1. Expanding clinical activities.
2. Recruiting, and
3. Increasing our CME outreach.
Clinical Activities. Our inpatient service is at Sharp
Mary Birch Hospital for Women, and the outpatient offices
are in the Frost Street complex adjacent to the Sharp/Rady
Children’s Campus, as well as in Encinitas, Murrieta, San
Ysidro, and Grossmont Hospital. The group’s consultation
and outpatient volume continues to increase; we project
that we will perform over 15000 ultrasound examinations,
over 700 fetal echocardiogram, and nearly consultations
this year. The group continues to limit our delivery volume
to 500-700 deliveries per year.
Recruiting. The Division of Maternal Fetal Medicine
welcomed Dr. Tevy Tith in August, 2013. Dr. Neha Trivedi,
who joined us in September 2011, will be leaving us for
Kaiser this year, and we are in the process of recruiting a
replacement for her.
CME. The Division continues to sponsor a yearly High
Risk Obstetrics course each fall, and a Prenatal Diagnosis
course each spring or early summer. Registration numbers
have risen each year. Our 2013 Prenatal Diagnosis Course,
at Scripps Schaetzel Center on May 31/June 1, attracted
over 200 participants, and we are in the final planning stages for our High Risk OB course, which will be on November 2 at the TriCity Hospital.
mfm v5.indd 16
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FACULTY
Val Catanzarite, MD, PhD,
Division Chief
Joanna Adamczak, MD
Holly Casele, MD
Larry Cousins, MD
Sean Daneshmand, MD
Wade Schwendemann, MD
Tevy Tith, MD
Neha Trivedi, MD
Tevy Tith, MD, joined the Division in Au-
gust, 2013. She received her undergraduate education at University of California,
Berkeley, and then completed Medical
School at UCSD, Residency in Obstetrics
and Gynecology at UCLA, and Fellowship in Maternal Fetal Medicine at UC
Irvine in July of 2013. Dr. Tith’s major
clinical interests include prenatal diagnosis, especially prenatal diagnosis of congenital heart defects, and diagnosis and
medical/surgical management of acute
maternal morbidities. Academic honors
include Charles Kimball Award for Best
Poster at the 2009 Pacific Coast Obstetric
and Gynecologic Society.
Research projects during fellowship
included:
• Maternal serum cytokine levels and
angiogenic factor levels in singleton
pregnancies conceived with assisted
reproductive technology versus spontaneously conceived pregnancies.
• Post-Cesarean hyperglycemic control
in Diabetic pregnancies and subsequent maternal complications
• Differential VEGF splicing in normal
pregnancies and pregnancies complicated by adverse outcomes
LEFT TO RIGHT: Val Catanzarite,
Holly Casele, Wade Schwendemann,
Joanna Adamczak, Larry Cousins,
Tevy Tith, Sean Daneshmand
Maternal Fetal Medicine
mfm v5.indd 17
17
1/27/14 10:48 AM
Dr. Tith is a member of the American
Congress of Obstetrics & Gynecology,
Society for Maternal Fetal Medicine, and
Society for Gynecologic Investigation.
She serves as a reviewer for the American
Journal of Obstetrics and Gynecology.
Dr. Tith speaks Cambodian and Spanish fluently.
Joanna Adamczak, MD, received her
undergraduate training at the University
of California, Santa Barbara, followed by
medical school at St. Georges University
and Obstetrics and Gynecology Residency at St. Barnabus Medical Center in
Livingston, New Jersey. Her fellowship
training was at Robert Wood Johnson
Medical Center and the University of
Pennsylvania. Academic honors include
Dean’s Honor Roll in medical school, and
election as a resident representative to
the Committee on Resident Education in
Obstetrics in Gynecology/Association of
Professors of Gynecology and Obstetrics
(CREOG/APGO). She has bee active in
the Crudem Foundation for Haiti Medical /Surgical Relief. During her fellowship
Dr. Adamczak achieved certification in
Fundamental Critical Care by the Society
of Critical Care Medicine.
Clinical interests include prenatal care
for women with complex medical complications including maternal cardiac disease, organ transplants and cancer, and
Dr. Adamczak also has a strong interest
in prenatal diagnosis. She is the fourth
memberofourDivisiontoprovideCVS.
Dr. Adamczak is fluent in Polish and
speaks Spanish as well.
Holly Casele, MD received her undergraduate degree magna cum laude from
Brown University, followed by medical
school and residency at Northwestern
University, where she was elected into
the Alpha Omega Alpha Honor Medical
society. She then completed a fellowship at the University of Pittsburgh, Magee-Women’s Hospital. She was an Assistant Professor at Northwestern University
Medical School and a senior attending at
the Evanston Hospital in Evanston, Illinois from 1997-2005, before joining our
group. She has been elected as one of
18
mfm v5.indd 18
America’s Best Doctors every year from
2007 to 2010 and again in 2013.
Dr. Casele’s clinical interests include
thrombophilias and thromboembolic disorders in pregnancy, a topic upon which
she has written and lectured widely; recurrent pregnancy loss, and noninvasive
screening for fetal aneuploidy. Dr. Casele
is certified for chorionic villus sampling.
Dr. Casele is currently a co-principal
investigator for a study assessing the accuracy of a noninvasive screening tool
for Down syndrome and other aneuploidy detections. She was instrumental in
bringing our ultrasound image storage/
reporting system online, and has been involved in the implementation of our Epic
electronic medical record system as well.
Larry Cousins, MD was a founding
member of the Maternal-Fetal Medicine
Division. His undergraduate education
was at UCLA, followed by medical school
and residency at Creighton University,
and fellowship at the Harbor/UCLA Program. Subsequently, Dr. Cousins taught
at the University of California, San Diego
(UCSD) and Loma Linda University, and
is a founding member of the Maternal Fetal Medicine group here.
Clinical interests include medical complications of pregnancy, particularly diabetes, and preterm birth prevention. He
has been very active at Sharp Mary Birch
Hospital for Women, where is currently a member of the ObGyn supervisory committee. He served as Director of
Maternal-Fetal Medicine at Sharp and
Co-Chair of the Women and Infants
Research Forum since 1991, Co-Chair
of the Perinatal Morbidity and Mortality Committee since 2004, and Chief of
Staff at Sharp Mary Birch in 2008-2009.
Dr. Cousins was honored with the Sharp
HealthCare Core Award for Quality Pillar for his work with the Cerner Design
Team in 2009, and received a commendation from Sharp Mary Birch for Perinatal Special Care Unit Teaching in 2009
as well. He has been selected as one of
America’s Top Doctors again in 2013.
Sean Daneshmand, MD received his
undergraduate degree from the UCSD,
completed medical school at New York
Medical College in Valhalla, New York,
residency at UCLA, and fellowship at
UCSD, before joining the Maternal-Fetal
Medicine Division in 2002.
Dr. Daneshmand has basic science
interests in the underlying triggers for
preterm labor, preterm rupture of the
membranes, and preeclampsia. Major
clinical interests include surgical complications of pregnancy and in particular
management of invasive placentation.
Dr. Daneshmand has also been very
active in fundraising for families with premature babies through Miracle Babies, a
nonprofit organization which he founded
in2008.MiracleBabies’activitiesin2013
included numerous charity events and
a run/walk that attracted >1500 participants. Under Dr. Daneshmand’s guidance,
the Miracle Babies foundation recently received a substantial grant award for study
of obesity in pregnancy. He has also been
selected by the San Diego County Medical
Society for Top Doctors honors.
Dr. Daneshmand speaks Farsi and
conversational Spanish.
Wade Schwendemann, MD joined
the Maternal-Fetal Medicine Division
in 2009. Dr. Schwendemann was a cum
laude graduate of Albion College in Michigan, then completed medical school at
the Medical College of Ohio in Toledo,
Ohio, residency at the University of Kentucky, and fellowship at the Mayo Clinic
in Rochester, Minnesota. Dr. Schwendemann has particular interests in simulation tools for teaching in maternal-fetal
medicine, and in the clinical arenas of
prenatal diagnosis and management of
multiple gestations. Dr. Schwendemann
provides chorionic villus sampling services for early prenatal diagnosis.
Dr. Schwendermann as involved with
development of the residency curriculum
while at Mayo Clinic, including modules
for preeclampsia/eclampsia/HELLP syndrome, and teaching of amniocentesis.
He is currently working with the blood
bank and American Red Cross to augment blood banking services in San Diego, with particular interest in the potential for public cord blood banking, and is
a member of the Board of Directors for
the blood bank.
1/23/14 4:40 PM
Neha Trivedi, MD, received her under-
graduate training at the University of California, Los Angeles, and medical education at the University Of Pittsburg School
Of Medicine, and then completed both
Obstetrics and Gynecology Residency
and Maternal Fetal Medicine Fellowship
training at the University of California,
San Diego. Academic honors include
Magna Cum Laude and Neurosciences
Departmental Honors while at UCLA,
Alpha-Omega-Alpha honors, the University of Pittsburg Humanism award in
2004, and an HIV/AIDS Education Leadership Award while in medical school, Dr.
Trivedi also received the Berlex Resident
Teaching Award during residency.
Dr. Trivedi has basic science interests in microRNAs in early mammalian
development. Her clinical interests include diabetes in pregnancy, biochemical
markers in prediction of pregnancy outcomes, trauma in pregnancy, and prenatal diagnosis.
Dr. Trivedi speaks Spanish and conversational Gujarti and Hindi.
Val Catanzarite, MD, PhD received his
undergraduate education at the California Institute of Technology, medical
school at UCSD and a PhD in Biophysics
at UC Berkeley, with thesis research in
the field of medical artificial intelligence.
He went on to residency at Stanford University Medical Center and fellowship at
the University of New Mexico. He taught
at UNM and the University of Arkansas
before returning to San Diego in 1989.
Dr. Catanzarite is a founding member of
the Maternal-Fetal Medicine Division.
Dr. Catanzarite has a longstanding interest in continuing medical education,
including computer based instruction.
Clinical interests include critical care
in obstetrics, prenatal diagnosis, diagnosis and management of cardiac abnormalities of the fetus, identification and
management of vasa previa, surgical and
medical prevention of preterm birth, and
emergency response teams in obstetrics.
Dr. Catanzarite has served as Codirector of the Sharp/Rady Children’s Prenatal Diagnostic Center since 1991, and
chairs the Sharp Mary Birch Pharmacy,
Nutrition and Therapeutics Committee.
mfm v5.indd 19
MAJOR
GOALS &
PLANS
Clinical Activities.
•
Frost Street Site. We moved into new office space at 7910
Frost Street, and increased the capacity of our prenatal diagnostic center on the central campus by 20%.
•
North County Coastal. In 2012, we moved our North County
Coastal office to the Sanford Clinic in Vista. We will soon offer
inpatient consultations at TriCity Medical Center.
•
Grossmont Hospital. We increased capacity at our Grossmont
site by 33% this year, and anticipate expanding availability of
fetal echocardiography at Grossmont during the fourth quarter
of 2013.
•
South Bay. We are developing an additional site on the Sharp
Chula Vista campus and increasing capacity at our San Ysidro
site.
Research. We anticipate wrapping up ongoing projects (outlined
above), and will soon submit a research protocol for a retrospective series of cases of prenatal diagnosis, obstetric and
surgical management and maternal/fetal outcomes of invasive
placentas.
Education: Rady and Arrowhead Medical Center are finalizing an
agreement that will bring Maternal Fetal Medicine fellows to
our centers for training starting in 2013 or early 2014. Our major CME events for 2013-14 will be a fall High Risk OB Course,
which will be presented on the TriCity Hospital campus, and
a spring Prenatal Diagnosis course. This year, we will update
our website (sandiegoperinatal.com) and improve/revise our
library of patient information and resources on that site.
1/27/14 9:53 AM
Dr. Catanzarite organizes the Division’s
monthly ultrasound and prenatal diagnosis conferences, and, has been course
coordinator for our High Risk OB and
Prenatal Diagnosis courses. He has also
been selected by the San Diego County
Medical Society for Top Doctors honors.
Dr. Catanzarite ran his 44th marathon
in 2011, and recently published a book,
Train Insane: Developing a lifelong plan
for ultimate fitness.
Dr. Catanzarite speaks conversational Spanish and Russian, and reads German and French. Since 2011, he has been
working on TORFL certification in Russian, and hopes to establish international
CME courses in collaboration with colleagues in Kiev, Ukraine.
RESEARCHACTIVITIES
Joanna Adamczak, MD
• (WithothersintheDivision):Prenatal
diagnosis, obstetric management, and
neonatal outcomes in vasa previa)
Holly Casele, MD
neonatal outcomes in vasa previa)
Val Catanzarite, MD, PhD
neonatal outcomes in vasa previa
• (With others in the Division): Fetal
anemia:Acomprehensivereview.
• (With others in the Division): OB
Team Stat at Sharp Mary Birch: the
first five years.
• (WithothersfromOBAnesthesiaand
PediatricSurgery):VACTERLinpregnancy:Areviewofmanagementissues
Larry Cousins, MD
• Intra-amniotic infection assessment
tools
neonatal outcomes in vasa previa.
Sean Daneshmand, MD
20
mfm v5.indd 20
Wade Schwendemann, MD
• (With others in the Division): Fetal
anemia:Acomprehensivereview.
MAJORPRESENTATIONS
Bird LM, Catanzarite V, Shea TJ, Willert
JR. The Association Of Alpha-Thalassemia With Congenital Anomalies.
David W. Smith Workshop on Malformations and Morphogenesis, Philadelphia, PA, August 2009
Cousins L. Natural progesterone administration and the risk of medical complications of pregnancy: secondary
analysis from a multinational, randomized, double blind, placebo controlled trial. Society for Maternal-Fetal Medicine Annual Meeting, San
Diego, CA, 2009
Schwendemann W. A Simulation Model
for Fetoscopic Laser Photocoagulation;
Society for Maternal-Fetal Medicine
Annual Meeting, San Diego, CA, 2009
Schwendemann W. VitaminCdoesnot
prevent ROS-mediated Syncytin expression or trophoblast differentiation. Society for Maternal-Fetal Medicine Annual Meeting, San Diego, CA,
2009
Schwendemann W. (1) Cervical models to teach interns accurate dilatationandeffacementassessmentskills
during pregnancy; (2) Improvement
in Breast Exam Skills During an Intern Training Program; (3) Changes
to the PRIMER (Procedural Centered
Repetition Involving Montessori-type
Experience and Rehearsal) Program.
CREOG/ APGO Annual Meeting, San
Diego, CA, 2009
Trivedi N, Phan, J Woelkers D. Urine
Sample Characteristics Do Not Affect Measurement of Urinary sFlt-1 or
PlGF. Society of Maternal Fetal Medicine, 2009 Annual Meeting, San Diego, CA, January 2009
Trivedi N, Valencia M, Basu T, Fortlage
D, Bansal V, Ramos G, Kelly T, Coimbra R. Radiation Exposure in the
PregnantTraumaPatient:Implications
for Fetal Risk Counseling. Society of
Maternal Fetal Medicine, 2009 Annual
Meeting, San Diego, CA, January 2009
Adamczak J, Critical Care Symposium:
case presentation, Society of Maternal
Fetal Medicine, 2009 Annual Meeting,
San Diego, CA, January 2009
Trivedi N, Valencia M, Bansal V, Kelly T,
Coimbra R, Moore T. The Predictive
ValueofInjurySeverityScoreonOutcomes of Pregnant Trauma Patients.
American College of Obstetrics & Gynecology, 2009 Annual Meeting, Chicago, IL, May 2009
Trivedi N, Tarsa M, Hartney C, Levy D,
Anton T, Pretorius D. Congenital
Cardiac Lesions: Prenatal Reading vs
Outcomes. American Institute of Ultrasound in Medicine, New York, NY,
April 2009
Trivedi N, Guo G, Robson P, Laurent L.
Do MicroRNAs play a role in early embryogenesis in Dicer 1-null mice? Society for Maternal Fetal Medicine Annual Meeting, Chicago, IL February 2010
Trivedi N, Wen E, Aguayo J, Tolen J,
Agent S, Ramos G, Moore TR. Impact
of Diagnostic Intervals in Gestational Diabetes on Glycemic Control and
Pregnancy Outcomes. Society of Gynecologic Investigation Annual Meeting, Orlando, FL, March 2010
Trivedi N, LaCoursiere Y, Wen E,
Aguayo J, Tolen J, Ramos G. The Impact of Depressed Mood on Glycemic
Control and Pregnancy Outcomes in
Women with Diabetes. Society for Gynecologic Investigation Annual Meeting, Orlando, FL, March 2010
Trivedi N, Liao X, Guo G, Robson P,
Liao X, Laurent L. The role of microRNAs in early mammalian development. International Society for
Stem Cell Research Annual Meeting,
San Francisco, CA, June 2010
Adamczak J. Maternal Height is independently associated with Cesarean
delivery. Poster presented at 2010
American College of Obstetrics and
Gynecology Annual Meeting
Gambling DR, Catanzarite VA, Partridge
BA. Obstetric and Anesthetic Management of a Parturient with VACTERL
Syndrome. Poster presentation, 2013
SOAP 45th Annual Meeting, San Juan,
PuertoRico,April24-28,2013
1/23/14 4:40 PM
Tith T. Diabetes, Pregnancy, and the
Heart. The Orange County Diabetes
Collaborative Conference. 7th Annual
Event, Children’s Hospital of Orange
County. April 2013
Tith T. Thromboprophylaxis in the
Post-Cesarean Patient. Current Controversies in Maternal Fetal Medicine.
Welsches, OR, August 2012
Tith T. Thromboprophylaxis in the Morbidly Obese Patient. Current Issues in
Perinatal Medicine. Palm Springs, CA,
September 2012
Tith T, Rastegar I, Holschneider HH, Axtell A. Peak Postoperative Glucose Is
A Predictor of Postoperative Complications in Patients Undergoing Major
Gynecologic Surgery. October 2009
Tith T, Rastegar I, Holschneider HH, Axtell A. Postoperative Glucose Is A Predictor of Postoperative Complications
in Patients Undergoing Major Gynecologic Surgery. Poster presented at
ACOG, San Francisco, CA, May 2009
Zhang HH, Wang YP, Tith T, Chen DB.
Analysis of Nitroso-Proteomes In
Normotensive and Severe Preeclamptic Placentas. Poster presented at Society for Gynecologic Investigation,
Miami, FL, March 2012
Tith T, Wang W, Hachey S, Hodges JK,
Chen DB. Differential VEGF mRNA
Splicing In Preeclampsia And Normal
Human Placentae. Poster presented at
Society for Gynecologic Investigation,
San Diego, CA, March 2012
Tith, T, Wen Wang, Deborah A. Wing,
John Kingdom, Dongbao Chen.
DifferentialVEGFmRNASplicingin
Preeclampsia and Normotensive Human Placentas. Poster submitted for
Society for Gynecologic Investigation,
Orlando, FL, March 2013
Bastek JA, Langmuir H, Kondapalli LA,
Paré E, Adamczak JE, Srinivas SK. Is
the administration of corticosteroids
costeffectiveforlatepreterminfants?
A decisioanalytic and economic analysis. Oral presentation at SGI 2012
Adamczak JE. Direct Measurements of
Cervical Remodeling for Predicting
Preterm Birth. The Cervix Study, poster presentation at SMFM 2012
PUBLICATIONS
Casele HL. The use of unfractionated
heparin and low molecular weight
heparins in pregnancy. Clinical Obstetrics and Gynecology, 49(4):895905, 2006.
Casele HL, Grobman W. Cost Effectiveness of thromboprophylaxis with intermittent pneumatic compression
at cesarean delivery. Obstet Gynecol,
108(3):535-40,2006.
Duhl AJ, Ural SH, Branch W, Casele HL,
Cox-Gill J, de Veciana M, Hamersley, SL, Hyers TM, Katz V, Kuhlman
R, Nutescu EA, Paidas M, Thorp JA,
Zehnder JA, for the Pregnancy and
Thrombosis Working Group. Am J
Obstet Gynecol,197(5):457,2007.
Catanzarite V, Hilfiker M, Daneshmand
S, Willert J. Prenatal diagnosis of fetal hepatoblastoma: Case report and
review of the literature. J Ultrasound
Med,27(7):1095-8,2008.
Schwendemann WD, O’Brien JM, Barton
JR, Milligan DA, Istwan N. Modifiable
risk factors for growth restriction in
twin pregnancies. Am J Obstet Gynecol.192(5):1440-2,2005.
Schwendemann WD, Contag SA, Wax
JR, Miller RC, Polzin WJ, Koty PP,
Watson WJ. Sonographic findings in
trisomy 9. J Ultrasound Med, 28(1):3942, 2009.
Nitsche JF, McWeeney DT, Schwendemann WD, Rose CH, Davies NP, Watson W, Brost BC. In-utero stenting:
Development of a low-cost high-fidelity task trainer. Ultrasound Obstet
Gynecol, 34(6):720-3,2009.
Schwendemann WD, Contag SA, Koty
PP, Miller RC, Devers P, Watson WJ.
Ultrasound findings in trisomy 22.
Am J Perinatol,26(2):135-7,2009.
Nitsche JF, McWeeney DT, Schwendemann WD, Rose CH, Davies NP, Watson W, Brost BC. In-utero stenting:
development of a low-cost high-fidelity task trainer.Ultrasound Obstet Gynecol, 34(6):720-3,2009.
Trivedi N, Ylagan M, Moore TR, Bansal
V,WolfsonT,FortlageD,CoimbraR,
Kelly T. Predicting Major Outcomes
Following Trauma in Pregnancy. Submitted to British Journal of Obstetrics
& Gynaecology.
Trivedi N, Tarsa M, Hartney C, Levy D,
Anton T, Pretorius D. Congenital
Cardiac Lesions: Prenatal Reading
vs Outcomes. Journal of Ultrasound
Medicine, in press 2011.
Ludmir J, Adamczak J, Schwartz N. In:
Gabbe:Obstetrics: Normal and Problem
Pregnancies, 6th ed Book chapter, Surgical Procedures in Pregnancy, 2010.
Adamczak J. Oyelese Y, Tobon L, Burton
A, Ashkinadze E, Canterino J, Smulian
J. The significance of a positive second
trimester serum screen for Trisomy
18. The Journal of Maternal-Fetal &
Neonatal Medicine, in press 2011.
Gambling DR, Catanzarite V, Fisher J,
Harms L: Anesthetic management of
a pregnant woman with GorhamStout disease. Int J Obstet Anesth,
20:85-8,2011.
Munden A, Butschek R, Poeltler D,
Krohne S, Tom W, Alió A. Ritter M,
Catanzarite, VA, Mendoza, A, Smith,
D, Friedlander, M, Friedlander, S: A
prospective longitudinal study documenting the incidence of infantile
hemangiomas and their association
with placental anomalies. Submitted
for publication 2011.
Cousins LM, Poeltler DM, Faron S, Catanzarite V, Daneshmand S, Casele
H. Nonstress testing at ≤ 32.0 weeks’
gestation:arandomizedtrialcomparingdifferentassessmentcriteria.Am J
Obstet Gynecol, 207(4):311.e1-7,2012.
Tith T, Rapkin A. Chronic Pelvic Pain of
EnterocolicOrigin.In:Chronic Pelvic
Pain. Oxford: Wiley-Blackwell Publishing, 2011.
In Submission:
Chen DB, Zhang HH, Feng L, Wang W,
Satohisa S, Tith T. S-nitrosylation of
cofilin-1 via eNOS derived NO is a
novel pathway for estradiol-17-induced endothelial cell cytoskeleton
remodeling. Hypertension, 2013.
mfm v5.indd 21
21
1/23/14 4:40 PM
Neurosurgery
Rady Children’s Specialists San Diego’s (RCSSD) Neurosurgery Division
has had a tremendously successful year, expanding its clinical activities
and research, training the next generation of pediatric neurosurgeons, and
continuing to broaden its national and international impact on neurosurgical care. Thanks to philanthropy and to the commitment of RCHSD
physicians, nurses, staff and volunteers, we are able to provide the best
neurosurgical care available to all children.
The Division of Neurosurgery is among the most respected centers in
the United States. The Division provides pediatric surgical evaluation, surgery and pre-operative and post-operative care for disorders of the brain,
spine and peripheral nerves. Among the conditions treated are cerebrovascular malformations, surgical treatment for epilepsy, peripheral nerve
disorders or injuries, brain and spinal cord tumors, cerebrospinal fluid diversion, and craniofacial diseases. From July 2011 to June 2012, RCSSD’s
Pediatric Neurosurgeons performed over 600 surgeries, including procedures for Brain Tumors (15%) including 17 skull base and 8 transsphenoidal approaches, Spinal Cord Tumors (3%), and CSF Diversion or shunting
procedures (10%) consisting of Revisions (6%), Insertions (6%), Lumbar
to Peritoneal Shunts (0.2%), and Reservoir Placement (0.5%). Our current
infection rate for CSF diversion is < 2.0%.
Other approaches included, Craniofacial Procedures (15%: 80% Open
and 20% Endoscopic), Epilepsy Surgery 6% (25% resective surgery and
75% VNS), Congenital Anomalies (Chiari Malformations 3%, Closed
Neural Tube Defects 3%, Open Neural Tube Defects 1%, and Encephaloceles 1%), Intracranial Cysts (5%), Brachial Plexopathies (0.7%), and
Vascular Anomalies (5%). Other cases included Skull Tumors (5%), Endoscopic Third Ventriculostomy (5%), and Trauma Related Cases (5%) with
42 Intracranial Monitor Placements. The overall infection rate was < 2%.
Operative Case Duration was mean 1.9 + 1.2 hours (Range 17 minutes
to 8.05 hours) with a MODE of 2 hours. 65% of the procedures were graded as significant intracranial or spinal interventions.
We continue to offer tertiary care services for some of the county’s most
complex cases, including cerebrovascular disease, skull base surgery, and
minimally invasive endoscopic approaches. We continue to have one of
the largest practices for tumors in the United States. Combined craniofacial and neurological surgery cases continue to increase from 2003 to
the present. A number of patients present from National and International
Referrals.
There has been significant growth in the Spasticity and Epilepsy Programs to date. The Pediatric Vascular Service remains one of, if not the,
busiest in the world.
neurosurgery v4.indd 22
1/23/14 4:42 PM
FACULTY
Michael L. Levy, MD, PhD, FACS,
FAANS Professor and Head, UCSD
RCHSD Division of Pediatric
Neurosurgery
Hal S. Meltzer, MD Professor, UCSD
Neurosurgery
John R. Crawford, MD Professor, UCSD
Neurology Director of NeuroOncology Program
Justin M. Brown, MD Assistant Professor and Head of Brachial Plexus
and Peripheral Nerve Surgery, UCSD
Neurosurgery
Alexander A. Khalessi, MD, MS
Assistant Professor and Head of
Pediatric Vascular and Endovascular
Surgery, UCSD RCHSD Division of
Pediatric Neurosurgery
Melissa A. Griffin RN, MSN, PNP
Pediatric Neurosurgical Nurse
Practitioner
Neurosurgical Teams
To maximize our ability to care for our
patients, multispecialty approaches to
complex neurosurgical issues have been
developed. To date these include:
Neural Tube Defects Team
The Neural Tube Defects Clinic at
RCHSD provides a comprehensive
management approach to children and
young adults with Neural Tube Defects,
both open and closed. The Clinic Team
includes Medical Directors Hal S.
Meltzer, MD and Andrew Skalsky, MD
(Director of Physiatry and the Pediatric
Rehabilitation Program). It is composed
of the specialties of Neurosurgery,
Orthopedics, Urology, Pediatric Surgery, Physiatry, Nursing, Enterostomal
Therapy, Physical Therapy, Occupational
Therapy, Genetic Counseling, and Social
Work. The clinic ensures that all patients
can be seen by multiple subspecialties
and makes available diagnostic and evaluative services, telephone consultation
for families and professionals, patient/
family education in Spina Bifida, patient/
family training in specific areas, such as
bladder and bowel management, skin
and wound care, genetic counseling,
limited psychosocial counseling, and
linkage to other clinical and community
services.
CNS Oncology Team
The Brain Tumor Service at RCHSD is
one of the largest pediatric care facilities for children with brain tumors in
the western United States. It consists
of physicians, nurses, social workers,
LEFT TO RIGHT: Hal Meltzer,
Melissa Griffin, Michael Levy,
Ashley Wagner
Neurosurgery
23
1/27/14 10:49 AM
child life specialists, parent liaisons and
chaplains who help each family through
the initial surgery and subsequent radiation and/or chemotherapy regimens.
Services involved include Hematology/
Oncology, Neurosurgery, Neurology,
Radiology, Pathology, Ophthalmology,
Craniofacial, Head and Neck Surgery,
and Rehabilitation. Children are treated
with state-of-the-art medical and surgical programs. The center specializes
in the treatment of complex tumors in
children involving the midline, posterior
fossa, Cerebellopontine angle, and skull
base. John R. Crawford, MD directs
the neuro-oncology program. He is the
co-director of the multidisciplinary
neuro-oncology clinic and leads the
Monthly CNS Tumor Conferences. He
has also developed close relationships
on an international level allowing for the
inpatient surgery and care for children
with complex brain tumor from both
Hospital Infantil de las Californias in
Tijuana and throughout the world.
Complex radiation therapies are
provided by Kevin Murphy, MD, who
serves as the Chief of the Pediatric
Radiation Oncology Service, and is
an active member of the Children’s
Oncology Group (COG,) and Hal S.
Meltzer, MD. Dr. Murphy also serves as a
regional resource and primary radiation
oncologist for RCHSD. Dr. Murphy
has used and fostered the development
of a number of emerging techniques
in the treatment of brain tumors in
children including Stereotactic Radiosurgery (SRS), Stereotactic Radiotherapy
(SRT), Intensity Modulated Stereotactic Radiosurgery/Therapy (IMRS/
IMRT), Hypo-fractionated Stereotactic Radiotherapy and Gliasite Iotrex
brachytherapy. Dr. Meltzer continues
to direct and develop the Gamma Knife
and Proton Beam Stereotactic Programs.
The Division has developed a tissue
bank at RCHSD (IRB 091542) and has
developed close relationships with laboratories at the Scripps Institute, UCSD, and
Burnham Institute over the past years.
Brachial Plexus Team
Justin M. Brown, MD continued to
direct a multidisciplinary team for
24
children with brachial plexus palsy, facial
nerve injury, and peripheral nerve injury
consisting of orthopedics, neurosurgery,
occupational therapy/hand therapy, and
physician assistants and nurse clinic
coordinators. He bring manys years of
expertise dealing with the complex issues
that can arise, and has evaluated hundreds of children with brachial plexus
injuries. The team provides comprehensive evaluations and follow-up services
as needed. Brachial plexus and other
peripheral nerve surgeries currently
represent a strength at RCHSD that we
continue to address in conjunction with
the UCSD Department of Neurosurgery.
Neurosurgery and
Pediatric Dysmorphology
Craniofacial Services and Plastic Surgical
Services and the Neurocraniofacial
Team at RCHSD are among the most
respected centers in the United States.
The Division’s surgeons and physicians
have achieved international reputations
in craniofacial surgery, genetics and
dysmorphology, neurological surgery,
bone biology and basic bone research,
and information technology. Presently,
the Division offers tertiary care services
for some of the county’s most complex
cases, including major skull base surgery,
endoscopic cranial reconstruction,
distraction osteogenesis for midface
and mandibular advancement, apnea
and airway problems in newborns and
children, orbital tumors, facial nerve
paralysis, microsurgery and pediatric burn care. From 2011 to 2012, we
performed 90 Craniofacial Procedures
(80% Open and 20% Endoscopic). The
Neurosurgical and Craniofacial Services
are seeing clinic patients primarily in the
Fresh Start Children’s Hospital Clinic
and involved directly with the patient
populations brought to RCHSD from
other countries for charitable surgical
interventions.
Neurovascular
A specific Vascular Clinic Program
is held at RCHSD with participation
from institutions throughout the San
Diego area including UCSD, Sharp,
San Diego Naval Medical Center and
Kaiser Permanente Medical Center. The
clinic is dedicated to a multidisciplinary
approach toward the management of
children and adults with complex or
deforming vascular lesions. Dr. Lawrence F. Eichenfield is director of the
vascular lesion clinic and is an internationally recognized expert in the area of
pediatric and adolescent dermatology.
The multidisciplinary team includes
renowned specialists in plastic and
craniofacial surgery, dermatology,
diagnostic imaging and interventional
radiology, laser surgery, genetics,
orthopedics, otolaryngology and ophthalmology. The Division initiated a
novel Cerebrovascular Multidisciplinary
Clinic in 2009 including Neurosurgery,
Neurology, Radiation Oncology, and
Neuro-interventional Radiology. We
now perform Pediatric Neuro-Interventional procedures at RCHSD with the
addition of Alexander A. Khalessi, MD,
MS. He performs both diagnostic and
therapeutic interventions for cerebral
vascular malformations and tumors in
children.
Membership in Professional Societies
Participation in professional societies has
occurred at the regional, national, and
international levels with a diffuse focus
on numerous aspects of medicine. At the
local level, Dr. Levy has been involved
with the Los Angeles County Medical
Association, Salerni Collegium-University
of Southern California School of Medicine, California House Officer Medical
Society, and Los Angeles Academy of
Medicine. At the regional level, Dr. Levy
has been involved with the California
Medical Association, California Neurosurgical Association for Pediatrics, the
American College of Surgeons in Los
Angeles and San Diego, the Western
Neurosurgical Society, and the San Diego
Medical Society. At the national level,
Dr. Levy has been involved with Alpha
Omega Alpha, the American Association
of Neurological Surgeons, the American
Medical Association, the Congress of
Neurological Surgeons, the Joint Section
of Cerebrovascular Neurosurgery, the
Joint Section of Pediatric Neurosurgery, the American Society of Pediatric
Neurosurgery
1/23/14 4:42 PM
Neurosurgery, the American College of
Surgeons, and the American Academy of
Neurological Surgery. At the international
level, Dr. Levy has been involved with the
Society of University Neurosurgeons and
the Italian Congress of Neurosurgery.
Dr. Levy is a member of the Physicians Advisory Committee on
Healthcare (2009–Current) and an
Honorary Chairman for the State of
California by the National Republican
Congressional Committee (Chairman Pete Sessions. He was a member
of the Member Benefit Development
Committee (2007–2011) for the
AANS, a member of the Executive
(2005–Current) and Future Meetings
(2006–Current) Committees for the
Society of University Neurosurgeons and
President Elect for 2015. Additionally,
he is a Surgical Consultant for the NFL
and NFL Players Association (NFLPA)
(2010–Current).
Reviewing Grants and Manuscripts
With regard to peer-review, Michael
Levy is a member of the Editorial Advisory Board for the journal Neurosurgery
(elected in 2009), the Journal of Health
Communications (1995–Current), and
World Neurosurgery (2009–current).
Michael Levy is currently an Ad hoc
reviewer for the Journal of Biomechanical
Engineering, M Sacks (ed.) (2008–Current), the Journal of Expert Review of
Dermatology (2007–Current), the Journal
of Neuropsychiatry and Clinical Neurosciences, S Yudofsky (ed.) 2007–Current,
and the Journal of Clinical Neurology and
Neurosurgery, E De Deyn (ed.) (2007–
Current). Michael Levy has additionally
served as a reviewer for AAAS Grant
Reviews (2010–Current) and previously
for the Wireless Augmented Reality
Prototype (WARP) In-Progress Review
for NASA Headquarters, Life Sciences
Division (NASA Code UL).
Michael Levy is currently on the
Medical Advisory Boards for the
National Hydrocephalus Association
(1998 –Current), Arachnoid Cyst
Foundation (2004–Current), Board of
Directors for the Autism Tree Project
Foundation (2002–Current), the Medical
Board of Directors for Stemedica Inc.
(2007–Current), and an Executive Member of the Medical Board of Directors for
the Holy Innocents Hospital, Mbarara,
Uganda (2010–Current). Michael Levy is
additionally a member for the Board of
Directors for the charitable organizations
INCA and OMNI.
TEACHING
The Division was certified by the American Board of Pediatric Neurological
Surgery to have a Board Certified Fellowship in pediatric neurosurgery with
inclusion in the Match beginning in
2009. Our current fellow, Alexa Reeves,
MD started the program in 2013. We also
continue to train International Fellows
throughout the world. Our first Fellow in
pediatric neurosurgery graduated in 2010
and is currently working at the Barrow
Institute in Phoenix, Arizona. Only 22
such Fellowships exist in the US and only
40% of those match a Fellow each year.
We review and participate in the clinical
in-service education programs and assure
the delivery of quality pediatric clinical services, as appropriate and feasible.
This results in our providing bi-monthly
conferences to the ICU Fellows, semi-annual trauma conferences, and bi-annual
lectures to the ancillary and nursing personnel in the IMU and ICU, lectures to
the Residents in pediatrics, and frequent
presentations at Grand Rounds and Morbidity and Mortality Conference. We also
participate in undergraduate, graduate
and post-graduate education programs.
We have been responsible for educational conferences including Pediatrics,
the Trauma Division, and the Pediatric ICU Team. Michael Levy continues
our yearly International Outreach Program with visits to pediatric facilities
in Managua, Nicaragua, Lima, Peru,
Kiev, Ukraine, and Mbarara, Uganda,
in the past years. Over the past two
years, Michael Levy has worked as an
Executive Board Member (and current
Medical Director) on the development,
and construction, and current medical
management of Holy Innocents Children’s Hospital in Mbarara, Uganda. He
travels there every January to assess medical care and institutional needs.
•
•
•
•
MAJOR
GOALS &
PLANS
Continue to develop what will be regarding
as one of the largest centers for the care
of children with tumors of the brain and
spinal cord in the United States.
Develop personalized therapies for the
management of children with malignant
brain tumors which will direct targeted
therapies developed based upon analysis
of the tumor type.
Complete the integration of CT imaging,
endoscopy, Pathology Telemedicine,
and three-dimensional imagingthe in the
Liam’s Neurosurgical Operative Suite.
Promote and further develop our clinical
relationships in Africa, Eastern Europe,
South, and Central America.
1/27/14 9:56 AM
We have assisted in developing an
Educational Skull Base Dissection Laboratory for resident education in surgical
anatomy and approaches. We have helped
to develop a 3D video display system
which maximizes the information available to residents and medical students
during surgery.
We have had significant involvement
in the education of pre-medical students,
medical students, residents, and fellows
over the past 15 years. At the national
and international level, Michael Levy has
been involved in the creation of numerous educational opportunities including
being a member of the CNS Publications
Committee (Current), and AANS Member Benefit Development Committee
(Current) which is a program that facilitates member education. For the Society
of University Neurosurgeons, he was Program Director of the Annual Meeting in
San Diego (2006), on the Executive Committee (2006–Current), and President
Elect in 2015. He currently serves as a
mentor for pre-medical students clinical
rotations (2003–Present) and as a mentor for UCSD pre-medical student and
resident international charity programs
including INCA, OMNI, Fresh Start, and
UCSD Project Nicaragua (2003–Present).
He was awarded the UCSD Division of
Neurosurgery Resident Teaching Award
in 2007.
AWARDS,HONORSAND
PRESENTATIONS
Divisional Publications
Peer Reviewed:
Hayden MG, Hughes S, Hahn EJ, Aryan
HE, Levy ML, Jandial R. Maria Auxiliadora Hospital in Lima, Peru as a
model for neurosurgical outreach to
international charity hospitals. Childs
Nerv Syst, 27:145-148, 2011.
Jandial R, Levy ML. Cellular Alchemy:
Induced Pluripotent Stem Cells Retain
Epigenetic Memory. World Neurosurgery, 75:5-6, 2011.
Newman CB, Park MS, Kerber CW,
Levy ML, Barr JD, Pakbaz RS.
Over-the-catheter retrieval of a
retained microcatheter following
Onyx embolization: a technical report.
J Neurointerv Surg, 10:1136, 2011.
26
Baird LC, Gonda D, Cohen SR, Evers LH,
Lefloch N, Meltzer HS, Levy ML. Craniofacial reconstruction as a treatment
for elevated intracranial pressure.
Childs Nerv Syst, 28:411-418, 2012.
Jandial R, Anderson A, Choy C, Levy ML.
Bidirectional microevnironmental cues
between neoplastic and stromal cells
drive metastasis formation and efficiency. Neurosurgery, 70N12-13, 2012.
Levy ML, Kasasbeh AS, Baird LC, Amene
C, Skeen J, Marshall L. Concussions
in Soccer: A Current Understanding.
World Neurosurg 78(5):535-44, 2012
Smith RD, Reeves A, Azeez A, Levy ML.
Human Oocytes Reprogram Somatic
Cells to a Pluripotent State. World
Neurosurg, 77:9-11, 2012.
Huang M, Nichols S, Robb A, Angeles
A, Drake A, Holland M, Asmussen S,
D’Andrea J, Chun W, Levy ML, Cui L,
Song T, Baker DG, Hammer P, McLay R,
Theilmann RJ, Coimbra R, Diwakar M,
Boyd C, Neff J, Liu TT, Webb-Murphy
J, Farinpour R, Cheung C, Harrington
DL, Heister D, Lee RR. An Automatic
MEG Low-Frequency Source Imaging Approach for Detecting Injuries in
Mild and Moderate TBI Patients with
Blast and Non-Blast Causes: NeuroImage, 61:1067-1082, 2012.
Harbert MJ, Yeh-Nayre L, O’Halloran H,
Levy ML, Crawford J. Unrecognized
visual field deficits in children with
primary central nervous system brain
tumors. Journal of Neuro-Oncology
107(3):545-549 2012.
Duenas VJ, Hahn EJ, Aryan HE, Levy
ML, Jandial R. Targeted neurosurgical outreach: 5-year follow-up of
operative skill transfer and sustainable
care in Lima, Peru. Childs Nerv Syst,
28:1227–1231 2012.
Levy ML, Duenas VJ, Hambrecht AC,
Hahn EJ, Aryan HE, Jandial R.
Pediatric Neurosurgery Outreach:
Sustainability Appraisal of a Targeted
Teaching Model in Kiev, Ukraine.
Journal of Surgical Education,
69(5):612–616 2012.
Wong RK, Emelin JK, Meltzer HS, Levy
ML, Cohen SR. Nonsyndromic Craniosynostosis: The Rady Children’s
Hospital Approach. J Craniofac Surg,
23(7 Suppl 1):S119-123 2012.
Northcott PA, DJH Shih, Peacock J, Garzia L, Morrissy S, Stütz AM, Zichner
T, Korshunov A, et. al Levy ML. Subgroup specific somatic copy number
aberrations in the medulloblastoma
genome. Nature, 488:49–56, 2012.
Udaka YT, Lanipua AY, Amene CS, VandenBerg SR, Levy ML, Crawford JR.
Recurrent Pediatric Central Nervous
System Low-Grade Gliomas: The
Role of Surveillance Neuroimaging in
Asymptomatic Children. J Neurosurg
Pediatr, 11(2):119-126, 2012.
Kharazi A, Lin CM, Visperas MC, Levy
ML. Chicken Embryonic Brain: An In
Vivo Model for Verifying Neural Stem
Cell Potency. JNS, 118:1-8, 2013.
Hambrecht A, Duenas MJ, Hahn EJ, Aryan
HE, Hughes SA, Waters D, Levy ML,
Jandial R. Strategic design for pediatric neurosurgery missions across the
Western Hemisphere. Surgical Neurology International, 4:62:1-3 2013.
Gold J, Levy ML, Crawford J. Giant
Plexiform Neurofibroma Causing
Asymptomatic Cervical Spinal Cord
Compression in a Child with Neurofibromatosis Type 1. BMJ, 1–3 2013.
Keshavarzi S, MacDougall M, Lulic
D, Kasasbeh A, Levy ML. Experience with the SURGICEL® Family
of Absorbable Hemostats (Oxidized
Regenerated Cellulose) in Neurosurgical Applications: A Review
WOUNDS W-12-00086 2013.
Markant SL, Esparza LA, Sun J, Barton KL, McCoig LM, Grant GA,
Crawford JR, Levy ML, Northcott
PA, Shih D, Remke M, Taylor MD,
Wechsler-Reya1 RJ. Targeting Sonic
Hedgehog-Associated Medulloblastoma Through Inhibition of Aurora
and Polo-Like Kinases. Cancer,
12-4258R-A, 2013.
Crawford J, Shayan K, Levy, M. Delayed
Presentation
of
Diencephalic
Syndrome Associated with Leptomeningeal Dissemination in a Child. BMJ
Case Reports, doi:10.1136, 2013.
Crawford J, Newbury R, Levy ML. An
Unusual Posterior Fossa Tumour in
a Young Child. BMJ Case Reports,
doi:10.1136, 2013.
Gonda DD, Meltzer HS, Crawford JR,
Hilfiker ML, Shellington DK, Peter-
Neurosurgery
1/23/14 4:43 PM
son BM, Levy ML. Complications
associated with prolonged hypertonic
saline therapy in children with elevated intracranial pressure. Pediatr
Crit Care Med, 14(6):610-620, 2013.
Ceponiene R, Levy ML, Crawford J:
Lobar haemorrhagic mass in a young
girl with neurofibromatosis type 1.
BMJ Case Reports, doi:10.1136, 2013.
Jankowski P, Levy ML, Crawford J: Post
Traumatic Basal Ganglia Haemorrhage in Child with Primary Central
Nervous System Lymphoma. BMJ
Case Reports, doi:10.1136, 2013.
Markant SL, Esparza LA, Sun J, Barton
KL, McCoig LM, Grant GA, Crawford
JR, Levy ML, Northcott PA, Shih D,
Remke M, Taylor MD, Wechsler Reya
RJ. Targeting Sonic Hedgehog-associated medulloblastoma through
inhibition of Aurora and Polo-Like
Kinases. Cancer Res, 2013 (in press).
Udaka T, Shayan K, Yeh-Nayre L, Levy
ML, Chuang N Atypical Presentation
of Atypical Teratoid Rhabdoid Tumor
in a Child Case. Rep Oncol Med, 2013
(in press).
Gold JJ, Dory CE, Levy ML, Crawford
JR Simultaneous Moyamoya Disease
and Cervical Spinal Cord Low Grade
Astrocytoma in a Child with Neurofibromatosis Type 1. BMJ Case Rep,
2013 (in press).
Crawford J, O’Halloran H, Levy ML: New
Presentation of Diabetic Embryopathy in an Infant with Femoral Facial
Syndrome, Holoprosencephaly, and
Resulting Hydrocephalus. Pediatrics,
2013 (In review).
Breithaupt A, Cohen SR, Meltzer H,
Broder K, Levy M. Endoscopic repair
of craniosynostosis: The role of minimally invasive techniques in the
treatment of single suture craniosynostosis (in press).
Hambrecht A, Jandial R, Levy ML. Strategic Design for Targeted Pediatric
Neurosurgery Teaching Missions
across the Western Hemisphere
(GHP-12-0071). Global Health Promotion, 2013 (in press).
Huang M, Huang C, Robb A, Angeles
A, Nichols S, Baker D, Song T, Harrington DL, Theilmann RJ, Srinivasan
R, Heister D, Diwakar M, Canive JM,
Edgar C, Chen YH, Zhengwei J, Shen
M, El-Gabalawy F, Levy ML, McLay R,
Webb-Murphy J, Liu TT, Drake A, Lee
RR. MEG Source Imaging using Fast
L1 Minimum-norm and its Application to Human Resting-state Signals.
NeuroImage, 2013 (in press).
Abstract/Poster Presentations
Peer Reviewed:
Levy ML, Baird L. Combined Approaches
for the Treatment of Craniopharyngioma. Presented at the Annual
American Society for Pediatric Neurosurgery, Lanai, Hawaii, 2011
Crawford JR. Predicting Recurrence in
Pediatric Central Nervous System
(CNS) Low Grade Gliomas: The Role
of MRI Surveillance in Asymptomatic Children. Presented at the Annual
American Association of Neurology
Meeting, Honolulu, Lanai, Hawaii, 2011
Levy ML, Baird L, Toney J. Punch Drunk.
Repetitive injury in boxing. Joe Louis.
Presented at the Annual Society for University Neurosurgeons meeting, Athens
Greece and Istanbul Turkey, 2011
Levy ML Concussion in young athletes.
Presented at the Annual RCHSD
When Youth Sports Get Dangerous
Symposium, San Diego, CA, 2011
Levy ML, Baird L. Complex Combined
Approaches for the Treatment of
Craniopharyngioma in Children.
Presented at the Annual American
Academy of Neurological Surgery,
Scottsdale, AZ, 2011
Gonda D, Meltzer HS, Levy ML. Hematologic Abnormalities Observed in
Pediatric Patients Treated with Prolonged Continuous Hypertonic Saline
for Elevated Intracranial Pressure.
Presented at the 61st Annual CNS
Meeting, Washington D.C., 2011
Gonda D, Meltzer HS, Levy ML. Incidence of Renal Injury and Failure
Measured by the RIFLE Scale in
Pediatric Patients Treated with Prolonged Continuous Hypertonic Saline
for Elevated Intracranial Pressure.
Presented at the 61st Annual CNS
Meeting, Washington DC, 2011
Menon J, Meltzer HS, Levy ML. The
use of flexible CO2 laser for albumin
solder-assisted dural tissue welding.
Presented at the 39th Annual ISPN
Meeting, Goa, India, 2011
Newman CB, Levy ML. Fatalities in Boxing and Proposal for Future Studies
in Combative Sports. Presented at the
12th Annual University of California
Neurotrauma Symposium, Santa Barbara, CA, 2011
Kim T, Gonda D, Meltzer HS, Levy ML.
Importance of Neurologic Exam in
Determining Management of Posterior Fossa Epidural Hematomas.
Presented at the 40th Annual Meeting
of the AANS/CNS Section on Pediatric Neurological Surgery, Austin, TX,
2011
Levy ML. Surgical intervention for hydrocephalus in Uganda. Presented at the
4th Annual Meeting of the ASAP
Building Sustainable Surgical Systems
Conference. San Diego, CA, 2011
Freestone L, Levy ML. Building a Children’s Hospital in Southern Uganda,
From Conception to Patient Care.
Presented at the 4th Annual Meeting
of the ASAP Building Sustainable Surgical Systems Conference. San Diego,
CA, 2011
Jandial R, Levy ML. INCA: Five-Year
Follow-up of neurosurgical Missions
to South and Central America. Presented at the 4th Annual Meeting of
the ASAP Building Sustainable Surgical Systems Conference. San Diego,
CA, 2011
Amene CS, Levy ML. Combined
Approaches in the Treatment of Craniopharyngioma. Presented at the
22nd NASBS 2012 Annual Meeting.
New Orleans, LA, 2012
Levy ML. Management of Pediatric Intracranial Gunshot Wounds: Predictors
of Favorable Outcome and a Proposed
Treatment Paradigm: Discussion.
Presented at the 2012 Annual AANS
Meeting, Miami, FL, 2012.
Yeh-Hauer L, Crawford J, Levy ML,
Lefloch N, Fagan M. Optimizing Care
of the Brain Tumor Patient Through
the Development of a Neuro-Oncology Primary Nursing Team. Presented
at the 36th Annual Meeting, Pittsburgh, PA, 2012
Levy ML. Learning from failure: Professional and personal resilience.
Neurosurgery
27
1/23/14 4:43 PM
Research Support
28
Grant/Contract #
Total Direct Dollars
Duration of Grant
Developmentofneuropathologycoretelemetryfortheintra-operativereview
of tissue harvested from children and adolescents with brain tumors
BioImagene
$280,000.00
2010-Current
PhaseI/II,multi-center,open-labelstudytoassessthesafety,tolerability,and
preliminary efficacy of a single intravenous dose of allogeneic mesenchymal bone
marrow cells to subjects with ischemic stroke
IRB#100325R/Stemedica(IND14328)
$812,736.00
2011-Current
AnexploratoryPhase2studyevaluatingtheefficacyandsafetyoffibrinsealant.
Vaporheated,solvent/detergenttreated(FSVSS/D)500S-APRforthesealing
of dura defect sutures in posterior fossa surgery
IRB# 12121/Baxter
$73,730.18
2010-2011
DiagnosingmildTBIinadolescentsandadultsusingMEGandDTI.
NFL
$99,741.00
2012-Current
Using Discarded CSF and Tissue to establish a neurosurgical tissue bank
RCHSDIRB#091542
Unfunded
2011-Current
Neurosurgical Database at RCHSD for prospective and Retrospective review of
neurosurgical cases
RCHSD IRB# 12120
Unfunded
2011-Current
PerformingAffymetrixSNP6.0arrayson>1200ofMAGICbankmedulloblastomasand
using nanostring to subgroup medulloblastomas.
RCHSDIRB#091542/UniversityofToronto
Unfunded
2011-Current
An Integrated MEG and DTI Study for Differential Diagnosis of Mild TBI and PTSD.
Huang(PI),Levy(Co-I)
1R01NS072601-01
Funded
2012-Current
Diagnosing Mild TBI in VA and Active Duty Military Patients using MEG and DTI.
Huang(PI)Levy,(Co-I)
1R01CX000499-01
Funded
2012-Current
Humanlysophosphatidicacid(LPAlevels)andgeneticmutationsinCNSbirthdefects.;
Yung(PI)ScrippsResearchInstitute,Levy(PI)
RCHSDIRB#091542
Funded
2011-Current
Developing an in vivo model for verifying neural stem cell potency in chicken embryonic
brain.Levy(Co-PI)
Stemedica/Department of Research and Development
Funded
2012-Current
UtilizationofintraoperativeCTangiographyandcomparisontostandardangiographyin
childrenwithvascularmalformations.Levy(PI)
RCHSD IRB# 12120/Ceretom Technologies
Funded
2011-Current
Targeting Sonic Hedgehog-associated medulloblastoma through inhibition of Aurora and
Polo-Like Kinases
RCHSDIRB#091542
Funded
2012-Current
Neurosurgery
1/23/14 4:43 PM
Presented at the Senior Society of
Neurosurgeons resident Boot-Camp
Annual Meeting, San Diego, CA 2013
RCHSD, Brain Trauma Research Focus
Group
RCHSD, Liam’s Fund Charity
Books Edited:
Berta S, Nader R, Levy ML (eds). Neurosurgery Tricks of the Trade Volumes 1
and 2, Thieme, New York 2013.
Establishment of New Teaching Venues
The Division has developed Educational
Skull Base Dissection Laboratories for
Resident Education in surgical anatomy
and approaches. We have worked with
Johnson and Johnson Medical to develop
educational materials regarding the use
of hemostatic agents during neurosurgical procedures.
RESEARCH AND FUNDING
Revolutionary surgical techniques and
technologically advanced approaches
remain a primary pursuit of the Neurosurgical Team. New technology in
neurosurgery includes the continued
development of novel Robotic and
three-dimensional endoscopes, High
Definition 3D monitors for intra-operative use, and the potential uses of
intra-operative CT imaging in 2013. We
continue to work with our partner companies to advance closer to the reality
of true stereoscopic endoscopes (Hans
Hoag, PhD–Endactive technologies; Wei
Su, PhD-IntraVista Medical Systems Inc.,
and Kaiser Medical). We have assisted in
the development of a 3D displays which
is utilized in our operative setting as a
front projection 3D image. The primary
purpose is for education and allowing
the nursing and anesthesia teams to be
consistently aware of the course of the
surgical intervention.
Current avenues of research also
include the evaluation of cGMP in novel
neuronal stem cell lines, MEG imaging
and neuropsychiatric testing for mild
closed head trauma in adolescents, and
the potential benefits of Neuronal and
Mesenchymal based stem cells for treatment of stroke.
UNIVERSITY AND
PUBLIC SERVICE
MichaelL.Levy,MD,PhD
RCHSD, Advertising and Public Relations
Committee
RCHSD, Innovation and Technology
Committee
RCHSD, HIPAC
RCHSD, U.S. News & World Report
Subcommittee
RCHSD, Academic Council Philanthropy
Team
PATENTS AND
INVENTIONS
Pluronic Surfactant Based Bone Wax
(CHLA #99-09 Bonewax) which
allows for the use of bone wax in all
scenarios without risk of infection or
non-union
EndActive Robotic Omnidirectional
Neuroendscope (Hans Hoag–California Institute of Technology–Inventor).
Development and Construction of the
HICH Children’s Hospital in Mbarara,
Uganda.
Project Nicaragua, INCA and Open
Mind Neurosurgical International
(OMNI), which are nonprofit organizations providing charitable medical
services in the form of neurosurgical
procedures and the provision of complex neurosurgical equipment to the
underserved and needy around the
world. In combination with the Variety Children’s Lifeline, neurosurgeons
from RCHSD have traveled to five
countries over the past two years. In
addition to the surgeries performed
in San Diego in 2010, members of the
Neurosurgery Division performed
surgeries in Lima, Peru, Managua,
Nicaragua, and Kiev, Ukraine through
these Pediatric Neurosurgical Outreach Programs.
PUBLIC SERVICE AND
OUTREACH PROGRAMS
The Autism Tree Project Foundation
which was founded in 2003 to promote autism education and provide
early intervention programs in the
California community. Our main
programs are a Preschool Screening
Program, A quarterly Mentor program that pairs families new to the
autism diagnosis with a “Mentor” to
support and guide the family as well
as assist in identifying autism related
resources in the community, and a
Preschool Teacher Training Program.
Liam’s Fund, which assists in procuring
sophisticated equipment for use in the
neurosurgical operating room in hopes
of reducing the number of surgeries
performed and significantly increasing
the number of successful procedures
for children requiring neurosurgical interventions. Over the past year
Liam’s Fund has assisted in the funding
of the Neurosurgical Operating room
at RCHSD, now called the Liam’s Fund
Neurosurgical Suite.
Holy Innocents Children’s Hospital
Board of Directors. assisted with the
1/23/14 4:43 PM
Ophthalmology
The Division of Ophthalmology has seven physicians, each of
whom is board certified by The American Academy of
Ophthalmology (AAO) and is a Member of the American
Association for Pediatric Ophthalmology and Strabismus
(AAPOS). The Division is one of the largest pediatric
ophthalmology groups in the United States.
Ophthalmology v6.indd 30
1/23/14 4:44 PM
FACULTY
Preeti Bansal, MD, Acting Director
Colin A. Scher, MD
Yvette M. Jockin, MD
Henry O’Halloran, MD
Angela M. Moll, MD
Edward W. Brown, MD
Chantal Boisvert, MD
Sandra Kohler, C.O., C.O.M.T.
Mona Adams, OD
Dr. Preeti Bansal is board certified in
Ophthalmology. She earned her medical
degree from the University of Kentucky
and completed her residency at the same
institution where she was awarded the
Tschafter Resident Teaching Award and
served as chief resident. She completed
a fellowship in Pediatric Ophthalmology and Strabismus at Duke University.
She has been with RCSSD since 2005.
She is currently the acting director of
the Division. She also developed and
runs Retinopathy of Prematurity screening and treatment program. Her special
interests include Retinopathy of Prematurity and Pediatric Cataracts.
Dr. Colin Scher has practiced pediatric
ophthalmology at Rady Children’s Hospital-San Diego (RCHSD) for over 20 years.
He earned his medical degree from the
University of Cape Town in South Africa.
While completing his ophthalmology
residency at the University of Pennsylvania, he was honored as the senior resident
who most exemplified the ideal university resident.
Dr. Scher has received awards from the
American Academy of Pediatrics and San
Diego City schools for outstanding care for
underprivileged and uninsured children.
In addition to treating pediatric patients,
Dr. Scher is a specialist in adult strabismus.
Dr. Yvette Jockin specializes in pediatric ophthalmology. She has practiced at
RCHSD since 1997. A summa cum laude
graduate, she earned her medical degree
from the State University of New York at
Buffalo, School of Medicine & Biomedical
Sciences where she was named class valedictorian. She completed a residency in
ophthalmology at Case Western Reserve
University Hospitals in Cleveland. Her
postgraduate training also included a
fellowship in pediatric ophthalmology at
Children’s Hospital of Philadelphia.
While attending medical school, she was
elected to the Alpha Omega Alpha Medical
Honor Society and received the Dr. Janet
M. Glasgow Award and the Dr. Thomas J.
Guttuso Ophthalmology Award.
LEFT TO RIGHT: Henry O’Halloran,
Jane Kelly, Chantel Boisvert,
Edward Brown
Ophthalmology
31
1/27/14 10:51 AM
Dr. Henry O’Halloran is European and
American board certified in ophthalmology. He joined Rady Children’s Specialists
of San Diego (RCSSD) Division of Ophthalmology in November 2000. He earned
his medical degree from Trinity College
Medical School in Dublin, Ireland. His
postgraduate training included a residency in ophthalmology in Ireland and
at the University of Kentucky in Lexington, where he served as chief resident. Dr.
O’Halloran also completed a fellowship
in neuro-ophthalmology at the University of Kentucky, where he was also an
assistant professor. Dr. O’Halloran’s clinical interests are in neuro-ophthalmology,
specifically in optic nerve disorders and
the management of head injury patients.
He is an active volunteer with the Mercy
Outreach Surgical Team and has acted as
director and treasurer of the team. He is a
director of the Scripps Mercy Foundation
and a board member of the American Ireland Fund.
in Montreal Canada. She completed her
Ophthalmology residency at the University of Montreal School of Medicine
where she also served as Chief Resident. Dr. Chantal is fellowship trained in
Pediatric Ophthalmology as well as Neuro-Ophthalmology.
Dr. Angela Moll is a graduate of Wayne
Dr. Mona Adams is a licensed Optom-
State University School of Medicine and
completed a residency at the Kresge Eye
Institute at Wayne State where she won
the Barsky Research Award. She served
as fellow in pediatric ophthalmology
and strabismus at Children’s Hospital
of Michigan. She has been with RCSSD
since 2008.
Dr. Edward Brown has 28 years of
experience in pediatric ophthalmology
providing routine and specialized eye
care for infants, children, and adolescents.
He graduated from Temple University
Medical School and spent his residency
in ophthalmology at the Oakland Naval
Hospital and the University of California,
San Francisco. He finished his training in
pediatric ophthalmology after completing a fellowship at the Children’s Hospital
of Los Angeles in affilliation with USC.
He recently joined RCSSD’s ophthalmology team after 25 years of private practice
here in San Diego.
Dr. Chantal Boisvert is the newest member of the Division having joined in July
2013. She attained both a Medical Doctorate as well as a Doctorate of Optometry
32
Sandy Kohler, CO has over 20 years of
experience in pediatric ophthalmology in
the U.S. and on numerous mission trips to
Mexico and Honduras. She received her
training at a consortium program involving Eastern Virginia Medical School and
Old Dominion University. As an Orthoptist, Sandy is uniquely skilled in the
evaluation and treatment of children and
adults with eye movement difficulties.
Her specialty is strabismus, amblyopia
and double vision for both adults and
children. Sandy has been with Rady’s for
over 13 years and is an active volunteer
on mission trips with Mercy Outreach
Surgical Team.
etrist who joined the group in 2012. She
completed her training at the Southern
California School of Optometry in Fullerton, California where she received several
scholarships and was the 1st place recipient at Southern California College of
Optometry Student Research Symposium.
Dr. Adams specializes in contact lens fitting and training for children and teens.
CLINICAL ACTIVITIES
All aspects of pediatric ophthalmology
are covered by the physicians. Subspecialty interests include oculoplastics,
neuro-ophthalmology, lens implants in
children, pediatric glaucoma and adult
strabismus. The Division also offers eyeglasses for all ages starting at birth, as well
as contact lens training and fitting, with
special expertise in aphakic babies.
A full time orthoptist is a member of
the group and provides management of
the non-surgical aspects of strabismus,
as well as amblyopia and refraction. She
is also responsible for keeping technical support up-to-date with the latest
techniques and equipment to maximize
patient care.
RCSSD Ophthalmology is based on
the RCHSD campus. The satellite clinics that are served include Encinitas,
Escondido, and Murrieta. The Division is
especially proud of our devotion to premature babies. We are the only group of
ophthalmologists servicing thirteen neonatal units ranging from Chula Vista in
the South, Oceanside in the North and
Rancho Springs in Riverside County.
The Division is also the only ophthalmology group that covers RCHSD for
inpatient consultations, emergency room
consultations, urgent care and trauma call.
All pediatric ophthalmology surgery
provided by the group is done at RCHSD.
RESEARCH ACTIVITIES
The Ophthalmology Division focuses
its research efforts on Pediatric Intraocular Lens implantation, pediatric
refractive surgery, pediatric glaucoma
and eye trauma.
Recent Clinical Trials:
• Clinical Study C-10-004 Durezol
Pediatric Cataract Study
• ClinicalEvaluationofMyopiaControl
Spectacles
• A multicenter Double-masked Randomized, Active Controlled Parallel
Study of the Safety and Efficacy of
Once daily Bimatoprost Preservative
free Ophthalmic Solution in Pediatric
Patients with Glaucoma
TEACHING ACTIVITIES
The Division of Ophthalmology offers
clinical training for medical students,
pediatric and family practice residents
and pediatric specialty fellows. The
Division is actively involved in clinical research and provides opportunities
for trainees to contribute to the fields of
Ophthalmology and Pediatrics.
PUBLICATIONS
O’Halloran HS. HIV-Neuroophthalmology. In: Continuum of Neurology, J.R.
Berger (ed), American Academy of
Neurology, in press.
Ophthalmology
1/23/14 4:44 PM
MAJOR
GOALS &
PLANS
•
•
•
•
•
•
•
Cement amalgamation with UCSD Department of
Ophthalmology
Develop a clinical research program when the joint Rady
Children’s Hospital-UCSD Ph.D. comes to fruition
Increase clinical presence in Murrieta and Encinitas
Rapid response to in-house consultations
Develop appropriately reimbursed contractual arrangements with regional and local NICUs
Clinic and OR teaching of ophthalmology residents
Increased teaching of residents in the hospital setting
1/27/14 10:05 AM
Orthopedics &
Scoliosis
The Pediatric Orthopedic and Scoliosis Division addresses
the unique musculoskeletal needs of growing children and
adolescents. Childhood injuries or disease may alter or
impede growth; Rady Children’s Specialists of Diego (RCSSD)
orthopedists work to ensure optimal lifetime function for every
child. In 2011, the Pediatric Orthopedic and Scoliosis Division
was ranked 4th in the nation by the U.S. News & World Report.
ortho surg v5.indd 34
1/27/14 10:34 AM
FACULTY
Scott J. Mubarak, MD, Professor of
Clinical Orthopedic Surgery, Department of Orthopedic Surgery, UCSD;
Vice Chief of Division of Orthopedic
Surgery, Rady Children’s Hospital
Medical Practice Foundation
Dennis Wenger, MD, Voluntary Clinical
Professor of Orthopedic Surgery,
UCSD; Director of Orthopedic
Training Program, RCHSD
Henry Chambers, MD, Professor of
Clinical Orthopedic Surgery, UCSD;
Director of Motion Analysis Laboratory, RCHSD; Director of Southern
California Cerebral Palsy Center;
Co-Director of Pediatric and
Adolescent Sports Medicine
Peter Newton, MD, Voluntary Clinical
UCSD; Chief of Division of
Orthopedic Surgery, Rady Children’s
Hospital Medical Practice Foundation, Director of Orthopedic Research
and the Scoliosis Service, RCHSD
C. Douglas Wallace, MD, Associate
Clinical Professor of Orthopedic
Surgery, UCSD; Director of
Orthopedic Trauma, RCHSD
Maya Pring, MD, Associate Clinical
UCSD
Burt Yaszay, MD, Voluntary Assistant
Surgery, UCSD
Eric Edmonds, MD, Assistant Clinical
UCSD Co-Director of Pediatric and
Adolescent Sports Medicine
Andrew T. Pennock, MD, Assistant
Surgery, UCSD
POSTDOCTORAL
FELLOWS
(2012-2013)
Avrum Joffe, MD
John Kempainen, MD
Brian Scannell, MD
Chris Souder, MD
(2013-2014)
Matt Hollenbeck, MD
Jonathan Peterson, MD
Lee Phillips, MD
Lissette Salgueiro-Canetti, MD
LEFT TO RIGHT: Maya Pring, Dennis
Wegner, Salil Upasani, Eric Edmonds,
Henry Chambers, Doug Wallace, Peter
Newton, Burt Yaszay, Scott Mubarak,
Andrew Pennock
Orthopedics & Scoliosis
35
1/27/14 10:52 AM
NURSE PRACTITIONERS/
PHYSICIAN ASSISTANTS
Chrissy Paik, PA-C
Amanda Asaro, PA-C
Linh Darnell, PA-C
Allison Dickinson, PA-C
Kathryn Fowle, CPNP
Lynn Manheim, CPNP
Sunny Park, CPNP
Kelly Pretorius CPNP
Raquel Sanchez, PA-C
Mary Lou Scott, CPNP
Phil Stearns, CPNP
Chris Orr, PAC
CLINICAL ACTIVITIES
The Division is the only comprehensive orthopedic group in San Diego
and Imperial counties with specialists
who practice full time pediatric orthopedics. By devoting their entire careers
to the care of children, these specialists
can provide individualized assessment,
early diagnosis, and appropriate treatment for all pediatric and adolescent
orthopedic problems, including: fracture
care (casting and/or operative fixation);
spine abnormalities (scoliosis, kyphosis
and spondylolisthesis); foot deformities
(Ponseti casting, tarsal coalition, toeing
in, clubfoot, flatfeet); hip disorders (hip
dysplasia and dislocation, Legg-CalvePerthes disease); sports medicine (knee
and shoulder arthroscopy) brachial
plexus palsy; and cerebral palsy (gait
enhancement).
The Division also works with RCHSD to
provide advanced biomechanical analysis
through the Motion Analysis Laboratory
and low dose pediatric imaging services.
RESEARCH ACTIVITIES
The orthopedic research program at
RCHSD is designed to keep the Division
at the forefront of advances in orthopedic
treatment in order to share best practices
and new discoveries within the field. The
program has attracted external grants
from industry, professional organizations
and federal sources, as well as philanthropic funding. In 2012, the department
members contributed to 51 scientific
presentations at national and international meetings (Annual Meetings of the
36
American Academy of Orthopedic Surgeons, Pediatric Orthopedic Society of
North America, Scoliosis Research Society, Orthopedic Research Society, and the
International Meeting on Advanced Spinal Techniques).
In addition to the Division’s ten
attending orthopedic surgeons, orthopedic research at RCHSD is conducted
and carried out by many other physicians, research support staff, and trainees.
Pediatric orthopedic fellows are actively
involved in research during their fellowship training year. International fellows as
well as residents from UCSD, the U.S. Navy
and U.S. Air Force regularly participate in
one or more research projects during their
rotations. Each year, the Division hosts a
resident from the UCSD orthopedic residency program for training in orthopedic
research. The Orthopedic Division also
has internal resources for conducting
sophisticated statistical analyses, which
lends enhanced scientific validity and
detailed data analysis to its research studies. The Division employs administrative
support for budgeting, contracting and
project management.
To further its research goals in clinical, biomechanical, and in vivo research
methodologies, the Orthopedic Division
has established specific synergistic centers of research:
• The Center for Spinal Deformities
Research
• TheCenterforPediatricandAdolescent Sports Medicine Research
• TheCenterforHipResearch
• The Orthopedic Biomechanics
Research Center
• The Motion Analysis Laboratory/
Center for Human Performance
The Center for Spinal Deformities
works with a very active clinical spine
service under the supervision of Dr. Peter
Newton. With the help of industry grants
and participation in the multi-center
international spinal deformity Harms
Study Group, the center has added three
full-time research staff and one research
nurse. The center’s research has primarily focused on identifying the optimal
treatment for adolescent idiopathic scoliosis (AIS) patients. Currently, all patients
undergoing surgical correction of AIS
are consented to participate in research
and followed for a minimum of five
years. The center collects pre-operative
and post-operative clinical and radiographic data, and performs pulmonary
function tests on each patient. A secure
web-based database allows all sites to
enter and query de-identified patient
data, which includes digital x-rays and
clinical photos. This system has proven to
be successful in advancing knowledge of
scoliosis treatment and help disseminate
treatment information at international
and national meetings, and in peer
reviewed journals. The center has also
launched similar prospective research
studies for Scheuermann’s kyphosis and
scoliosis in patients with Cerebral Palsy,
and plans to continue in vivo research
and its work with the Orthopedic Biomechanics Research Center. It also serves
as a site for a multi-center, NIH funded
study investigating the efficacy of bracing in patients with adolescent idiopathic
scoliosis. All patients who visit the orthopedic department for clinical evaluation
of spinal deformity undergo radiographic
examination in the EOS® Imaging booth,
which allows for a fast, biplanar, lowdose, standing x-ray acquisition. These
images are also capable of undergoing 3D
reconstruction for research purposes.
The Center for Pediatric and Adolescent Sports Medicine Research is our
youngest center, established to support
the efforts of the surgeons within the 360
Sports Medicine program at RCHSD.
The research within this center focuses
on specific sports related injuries, as well
as general orthopedic trauma treatment
– which quite often are a result of sporting activity. Projects within this center
have examined the outcome of varying
treatment approaches for skeletal injuries and predictors of treatment failures.
The surgeons in this center are currently
participating in prospective multi-center
studies to develop registries for clavicle
fractures and treatment of osteochondritis
dissecans of the knee. Extensive study into
shoulder injuries in children and adolescents is also a major focus and efforts are
currently underway to validate a subjective shoulder outcome tool specific to this
age group. Efforts to better understand
1/23/14 4:45 PM
MAJOR
GOALS &
PLANS
The Pediatric Orthopedic Division at RCHSD and UCSD
is recognized as one of the best in the world for its clinical care, innovative teaching and advanced research.
The Division plans to:
•
Be the top children’s clinical and research orthopedic
center in the United States, drawing patients from
throughout the western United States, as well as
Europe, Central and South America, and Asia. The
quality of the Division’s clinical work and outstanding
research will ensure state-of-the-art methods for
treating children’s conditions.
•
Continue its widely recognized fellowship training
program in children’s orthopedics while supplementing the international fellowship division to ensure that
there are always two or three international fellows
conducting research with the North American fellows.
•
Actively raise funds for additional research and
establish at least three funded, named eponymous
professorships in children’s orthopedics.
•
Expand research and clinical assessment of
3-dimensional spinal and limb alignment with new
EOS x-ray machine, which allows for up-right weight
bearing exams.
1/27/14 10:12 AM
Research Support
Grant/Contract #
Duration of Grant
Insall vs. MPFL Reconstructive Surgery for Recurrent Patella Instability (Edmonds)
UCSD (sub-award)/OREF
$141,865
Jan. 2011-Dec. 2013
St.GilesYoungInvestigatorAward:BarFormationinPhysealFractures:TheUtilityof
Interpositional Fat Graft Using Laprine Model
Pediatric Orthopedic Society of North America (POSNA)
$7,635
July 2010-June 2012
10 year follow ups: Prospective Study of Motion Preservation Evaluation below
Fusions of the Spine in Adolescent Idiopathic Scoliosis (Newton)
SSSF/SRS
$9,586
Apr. 2010-Sept. 2012
Three-Dimensional Analysis of the Deformation and Corrective Forces in the Spinal Rods
for Scoliosis Correction (Newton)
Pediatric Orthopaedic Society of North America (POSNA)
$25,000
Mar. 2010-May 2011
BracinginAdolescentIdiopathicScoliosis(BrAIST)(Newton)
University of Iowa (NIH SubAward)
$19,278
Sept. 2010-Aug. 2013
BrAISTII:Minimum2-YearFollow-upofBrAISTCohort(Newton)
University of Iowa
$4,338
Jan. 2013-June 2014
3DVisualizationofVertebralGrowthCartilageandDisc;theEffectsofGrowthModulation $9,987
(Newton)
Mar. 2011-Mar. 2012
Scoliosis Research Society (SRS)
38
FOX Pediatric Spinal Deformity Study (Newton)
WashingtonUniversity(JohnandMarcellaFoxFundSubaward)
[ $ missing ]
Oct.2010-Dec.2015
ProspectiveStudyofScheuermann’sKyphosis(Newton/Yaszay)
SSSF/DePuy Synthes Spine
$18,300
Nov. 2010-Dec. 2013
ScoliosisSurgeryOutcomesDatabaseRegistry:AProspective,Multi-centerDatabase
Registry of the Harms Study Group (AIS) (Newton/Yaszay)
SSSF/ DePuy Synthes Spine
$345,967
Nov. 2010-Dec. 2016
Prospective Study of Cerebral Palsy Scoliosis (Newton/Yaszay)
SSSF/ DePuy Synthes Spine
$126,840
Nov. 2010-Dec. 2016
ProspectiveStudyofMotionPreservationEvaluationbelowFusionsoftheSpinein
Adolescent Idiopathic Scoliosis (Newton/Yaszay)
Setting Scoliosis Straight Foundation(SSSF)/ DePuy Synthes Spine
$59,875
Apr. 2009-Dec. 2013
InVitro,BiomechanicalAnalysisofUpperFoundationSpineandRibAnchors(Glaser)
San Diego Spine Foundation (SDSF)
$4,051
Oct. 2010-Oct. 2011
Validation of the EOS 3D Reconstruction Accuracy against CT (Glaser)
EOS Imaging
$20,839
Jan. 2011-June 2011
1/23/14 4:45 PM
Research Support
Grant/Contract #
Duration of Grant
Real-TimeAnalysisoftheBiomechanicsandtheEffectivenessofFusionlessSpinal
Growth Modulation Devices (Glaser)
Scoliosis Research Society (SRS)
$25,000
Mar. 2011-Mar. 2013
Foot Drop Device (Glaser)
US Navy Medical Center
$146,625
Sept. 2012-Sept. 2013
Three Dimensional Analysis of the Growth Plate and Intervertebral Cellular Responses
to Spinal Growth Modulation in the fusionless Treatment of Scoliosis:
A Pilot Study in an Immature Porcine Model
Orthopedic Education and Research Foundation (OREF)
$5,000
July 2013-June 2014
sports injuries radiographically have also
been undertaken, in collaboration with
pediatric radiologists at this institution.
The efforts of the Center for Hip
Research revolve around the four major
diagnoses encountered by pediatric hip
surgeons; developmental dysplasia of
the hip (DDH), Legg-Calve-Perthes disease (Perthes), slipped capital femoral
epiphysis (SCFE), and femoroacetabular
impingement (FAI). Research into these
four conditions attempts to better understand the evolution of the conditions,
stages of disease, and the ideal treatment
outcomes. Our department is participating in a multi-center prospective study
evaluating the treatment outcomes for
patients with DDH, as part of the International Hip Dysplasia Institute (IHDI).
A prospective registry to gather extensive
data on patients with FAI was recently
established and it is anticipated a similar
approach to SCFE patients will be undertaken with the next year. This research
center has also taken advantage of the
opportunity created by the EOS® Imaging booth, which allows for standing
radiographic image of the pelvis. Recent
studies have evaluated pelvic parameters
in this natural standing state in scoliosis
patients with no hip disease as well as
patients with symptomatic hip disease.
Future work will explore the capabilities
of the system for creating 3D reconstructions of the pelvis and femur.
TheOrthopedicBiomechanicsResearch
Center(OBRC),foundedin1998andled
by Dr. Peter Newton under the direction
of Diana Glaser, PhD, applies advanced
engineering tools and methods to evaluate
techniques and instrumentation used to
correct orthopedic problems and deformities. The lab has received several grants to
evaluate current spinal devices and a new
technique for fusionless scoliosis surgery.
These studies, along with research presentations and publications, have made the lab
a world-recognized facility in this area of
orthopedic research. The lab has also made
significant progress toward understanding
the biomechanical effects of various surgical techniques for stabilizing adolescent
fractures of the humerus, femur and tibia,
and in exploring the biomechanical effects
of pediatric hip deformity.
These cumulative research efforts have
been accomplished by pairing orthopedic surgeons and biomedical engineers
with orthopedic residents and fellows.
Engineering interns and medical students are also recruited to help with each
project. This multi-layered approach has
yielded significant success with prolific
publications appearing in Spine, the Journal of Pediatric Orthopaedics, Clinical
Orthopaedics and Related Research, the
American Journal of Sports Medicine,
the Journal of Shoulder and Elbow Surgery, Medicine and Science in Sports and
Exercise, the Journal of Foot and Ankle
Surgery, Arthroscopy and the Journal of
AppliedBiomechanics.
The Motion Analysis Laboratory
(MAL) has been utilizing and developing
technological resources for the advanced
diagnosis and treatment of orthopedic
problems since 1974. Led by Dr. Henry
Chambers, the internationally recognized MAL specializes in the diagnosis
and treatment of orthopedic dysfunction
in cerebral palsy. The MAL uses modern
computer technology and high-speed
digital cameras to obtain detailed reports
of how patients move while walking
compared to age-related data of normal
walkingpatterns.Bystudyingthedifferences, an orthopedic surgeon can develop
an individualized treatment plan, with
recommendations for orthoses, physical
therapy or surgery, if necessary.
The Center for Human Performance
(CHP) was established by Arnel Aguinaldo, MA in 2001. Utilizing MAL
technology, the center’s main objectives
are studying and providing feedback on
athletic performance and injury prevention in such areas as pitching, golf swing,
running, and archery for children, adults
and athletes of all ages and levels of competition. The MAL and CHP continue to
be at the forefront in the field of human
motion study.
AWARDS, HONORS AND
MAJOR PRESENTATIONS
ScottJ.Mubarak,MD
• SeniorAchievementAward,AAOS2013
• ElectedtoUCSDAcademyofClinician
Scholars 2011
• SteroidInjectionForUnicameralBone
Cysts Of The Proximal Humerus In
39
1/23/14 4:45 PM
•
•
•
•
40
The Skeletally Immature. (Bray, Moor,
Mubarak). Pediatric Orthopedic Society of North America (POSNA) Annual
Meeting, Toronto, CA, May 2013
IPOTT Annual Meeting, Sausalito,
CA, October 21, 2011
- Classification and the Need for
Intra-Articular Fracture in Children
- Septic Arthritis Associated with Closed
Intra-Articular Fracture in Children
International Pediatric Orthopedic Symposium Annual Meeting,
Orlando, FL, December 7-10, 2011
- The Pavlik Harness remains the standard for DDH
- Case Discussion: Solving DDH
before it Needs an Operation
- Practice Management Seminar:
ARS Electronic Record, Physician
Extenders, Private Practice vs. the
Center, When contracts Are Bad,
Partnering With The Hospital, Fracture Care (Managing The Load,
Intrusion From Non-Orthopedists),
CompensationStrategies,Billing
- Growth control strategies around the
ankle
- Case Discussion: Fibular deficiency,
Deformity around the Ankle
-BreakoutSession:Forefoot:LongitudinalEpiphysisBracket
4th Posi-Posna Workshop. Pune,
India, January 13, 2012
- Management of the Knee and
Crouch Gait in CP
- Special Guest Lecturer. Acute Compartment Syndromes in Children:
diagnosis and Treatment
- Examination Under Anesthesia,
Closed Reduction, Arthrography
and Spica Application for DDH
Curso Internacional Pe Infantil e do
Adolescente Annual Meeting, Sao
Paolo,Brazil,March16-17,2012
- Compartment syndrome
- Management of CavoVarus Feet
- Management of Tarsal Coalition
- Management of the Foot in Cerebral
Palsy
- Management of Foot Deformities in
Duchene Muscular Dystrophy
-BracketEpiphysisoftheMetatarsal
- Ankle Fractures: Prevention of
Growth Plate Closures and Foot/
Ankle Deformity
•
•
•
•
•
•
- Osteochondritis of the Foot
- Tib-Fib Synostosis and effects on the
Foot/Ankle
Orthopedic Conference, Manaus,
Brazil,March19-20,2012
- Compartment Syndromes
- Tarsal Coalition
ABJS Annual Meeting, Charleston,
SC, May 3, 2012
- Contemporary Imaging for Tibial
Tubercle Fracture Patterns in Adolescents: Need for Intra-articular
Assessment
POSNAAnnualMeeting,Denver,CO,
May 17, 2012
- Risk Factors for Compartment Syndrome After Flexible Nailing of
Pediatric Tibial Shaft Fractures
-Lower Extremity/Neuromuscular
Symposium
- Flatfoot in Cerebral Palsy, the 3C
Procedure
- Salter-Harris II Fractures of the Distal Tibia: Does Surgical Management
Reduce the Risk of Premature Physeal Closure?
- Contemporary Imaging for Tibial
Tubercle Fracture Patterns: Need for
Intra-articular Assessment. e-Poster
IPOTT Annual Meeting, Cannes,
France, September 22, 2012
- Pathomechanics of Gowers’ Sign: A
Video Analysis
IPOS Annual Meeting, Orlando, FL,
November 29, 2012
- My Pavlik Harness Protocol and
What I do When it Fails
- Resect a Tarsal Coalition
- Tarsal Coalitions: Resect It & You’re
Done: Leave it Flat. Adult vs. Ped.
Smackdown: POV
- Ponseti Casting: Initial Management.BreakoutSession
-Ponseti Complex Problems. Breakout Session
- Pediatric Foot: Surgery Management of
Congenital and Acquired Conditions
- Controversies – Is there an Answer.
Moderator
AAOS Annual Meeting, Chicago, IL,
March 23, 2013
- Pavlik Harness Treatment: What to
do and what not to do?
- Infantile
DDH:
Screening,
Safe-swaddling, Harness Application
and Follow-up Protocol. Scientific
Exhibit SE42
- Does Surgical Management Reduce
the Risk of Premature Physeal Closure in Salter-Harris II Distal Tibia
Fractures? Poster No. P492
• POSNA Annual Meeting, Toronto,
Ontario, Canada, May 2, 2013
- Use of Mid-level Providers in Pediatric Orthopedics
- Reliability of a New Radiographic
Classification of Developmental
Dysplasia of the Hip
- Negotiation in Practice: How to Get
BothWhatYouNeedandWhatYou
Want
- Steroid Injection for Unicameral
BoneCystsoftheProximalHumerus
in the Skeletally Immature
- Does Portable Intraoperative CT
Scan Improve the Quality of Talocalcaneal Coalitions? Paper Poster #20
Dennis R. Wenger, MD
• 2011 MacLaggan Award for International Service to Children
• Downtown San Diego Rotary Club,
San Diego, CA
• Teton Valley Pediatric Orthopedic
Society Meeting, Driggs, ID, September 23-24, 2011
- The Osteochondroma Count in
MHE: New Thoughts on Glycobiology, Spine Surgery and Ear
Reconstruction–StrangeBedfellows
• 19th Annual Meeting of the Iranian
Orthopedic Association, Tehran, Iran,
October 17-21, 2011
- Modern Management of LCPD:
Advanced Containment Method-Triple Innominate Osteotomy
- Management of SCFE In The
Impingement Era
- Management of Neuromuscular Hip
- Approach To Re-Dislocation After
DDH Treatment
- Modern Management of LCPD
- Surgical Management of Flat Foot
Disorders & Tarsal Coalition
• International Pediatric Orthopedic
Think Tank, Sausalito, CA, October
20-22, 2011
- The Osteochondroma Count in MHE:
New Thoughts on Glycobiology
- Spine Surgery and Ear Reconstruc-
1/23/14 4:45 PM
tion–StrangeBedfellows
• 8th Annual International Pediatric
Orthopaedic Symposium, Orlando,
FL, December 7-10, 2011
- Legg-Calve Perthes, ICL Instructor
- Treating Severe Acetabular Dysplasia with the Triradiate Open, Invited
Lecture
- Case Discussion: Mature Perthes
with Hip Pain, ICL Moderator
- Pelvic Osteotomies – Hands On:
Basic(Salter,Dega,Pemberton),ICL
Instructor
- Pelvic Osteotomies – Hands On:
Advanced (Ganz, Triple, Others),
ICL Instructor
• American Academy of Orthopedic
Surgeons Annual Meeting, San Francisco, February 7-11, 2012
- Managing Hip Dysplasia after Triradiate Closure – Treatment for
the Adolescent and Young Adult,
Instructional Course Lecture
- Surgical Management of Hip Dislocation, Instructional Course Lecture
• AAOS – TOTBID Lectures, Antalya,
Turkey,April18-20,2012
- ESIN Method for Treating Childhood Femur Fractures
- Forearm Fractures in Children
- Principles in the Treatment of
Perthes Sequelae
• Pediatric Orthopedic Surgeons of
North America (POSNA), Annual
Meeting – Hip Course, Denver, CO,
May 16, 2012
- Is There a Role for Acetabular
Dysplasia Correction in an Asymptomatic Patient?
• 5th Annual Kenneth G. Burton MD
Visiting Professorship, University of
Rochester, New York, October 16-18,
2012
- Will Your Child Live to be 100?
Orthopedic Thoughts on the
Demand
for
Musculoskeletal
Perfection
- Understanding and Treating Tarsal
Coalition in Childhood – from R.I.
Harris and the Canadian Army to
Advanced 3D CT Imaging
Symposium (IPOS), Orlando, FL,
November28-December1,2012
- Perthes – When to Operate? (Paper)
- Challenging Decisions in Pediatric
Hip Surgery (Panel Moderator)
- Pelvic Osteotomies – Hands-on:
Basic,PanelMember
- How to Perform a Triple Innominate
Osteotomy, Paper
- Pelvic Osteotomies – Hands on:
Advanced, Panel Member
- Treating Complex Hip Disorders,
Moderator
- Pelvic Osteotomies – Hands on:
Advanced, Panel Member
• AmericanAcademyofOrthopedicSurgeons, Chicago, IL, March 20-22, 2013
- ICL 365: Current Perspectives on
the Diagnosis and Management of
DDH through Early Adulthood,
Co-Moderator
• POSNA Specialty Day – Chicago, IL,
March 23, 2013
- Surgical Management of Hip Dislocation (DDH), Lecturer
-Dysplasia Symposium - Case-Based
Discussion (DDH), Moderator
Henry G. Chambers, MD
• Excellence in Philanthropy Award:
Rady Children’s Hospital
• BestDoctorsinSanDiego
• BestDoctorsinAmerica
• U.S.News&WorldReportTopDoctors
• AmericanAcademyforCerebralPalsy
and Developmental Medicine, Las
Vegas, NV, October 2011
- Transcriptional Profile of Spastic
Hamstring Muscles in Children with
Cerebral Palsy
• ASAP(AllianceforSurgeryandAnesthesia Presence) Global Surgery Conference,
San Diego, CA, November 2011
- Orthopedic Surgery: Lessons learned
from Haiti
• AAOS/ POSNA International Pediatric Orthopedic Symposium, Orlando,
FL, December 2011
- Cerebral Palsy and Gait Analysis
- Prevention of Infections in Pediatric
Orthopedic Surgery
- Orthopediatrics Distal Femoral
Extension Osteotomy Workshop
- Orthopediatrics Proximal Femoral
Blade Plate and Femoral Locking
Plate Workshop
- Orthopediatrics Miserable Malalignment Workshop
- Cerebral Palsy Session: Hip and Foot
- Treatment of Tibial Eminence
Fractures
- Sports Injuries in Children: Panel
- Treatment of Spasticity in Children
with Cerebral Palsy
- Treatment of Rectus Femoris Spasticity: Transfer vs Release
• Society of Military Orthopedic Surgeons (SOMOS) Annual Meeting, San
Diego, CA, December 2011
- Pediatric Knee Problems
- Moderator of Pediatric Papers
• Rocky Mountain Hospital for Children: Pediatric Sports Medicine and
TraumaSymposium,BeavrCreek,CO,
January 2012
- Tibial Tubercle Fractures
Surgeons Annual Meeting, San Francisco, CA, February 2012
- Sports Medicine Problems in Children and Adolescent
- Osteochondritis Dissecans of the Knee
• POSNA/AOSSM Specialty Day, San
Francisco, CA , February 2012
- Treatment of Anterior Knee Pain in
Children and Adolescents
• PediatricandAdolescentSportsMedicine, San Diego, CA, March 2012 ,
Course Co-Director, Moderator of
Orthopedic Section
- The Knee in Pediatric and Adolescent Sports
- Developmental and Psychological
Aspects of Pediatric Sports Medicine
• Southern California Conference for
Adults with Cerebral Palsy, Rancho
Los Amigos National Rehabilitation
Hospital, Downey, CA, March 2012
-BonesandGroans:AgingwithCerebral Palsy
•SportsSymposium,PediatricOrthopedic Society of North America, Denver,
CO, May 2012
- The Future of Pediatric Sports Medicine: Panel Member
- Update on Patellofemoral Disorders
in Children
• GCMAS Symposium: Clinical Applications and Impact of Comprehensive
Motion AnalysisAmerican Academy
for Cerebral Palsy and Developmental
Medicine, Toronto, Ontario, Canada,
September 2012
41
1/23/14 4:45 PM
- The Impact of Motion Analysis on
the Treatment of Movement Disorders: The Last 30 Years
• American Academy for Cerebral
Palsy and Developmental Medicine,
Toronto, Ontario, Canada, September
2012
- Orthopedic Surgery for Adults with
Cerebral Palsy
-KneeandFoot/AnkleSurgery
Surgery West Coast Maintenance of
Certification (MOC) Review Course,
San Francisco, CA, November 2012
- Pediatric Lower Extremity Problems
- Neuromuscular Diseases
- Growth Disturbances
- Panel on Pediatric Topics
• AAOS/ POSNA International Pediatric Orthopedic Symposium, Orlando,
FL, December 2012
- Orthopediatrics Distal Femoral
Extension Osteotomy Workshop
- Orthopediatrics Proximal Femoral
Blade Plate and Femoral Locking
Plate Workshop
- Orthopediatrics Miserable Malalignment Workshop
- Imaging and Classification of OCD
- Sports Injuries in Children: Panel
-BracingandSpasticityManagement
in Children with CP: Moderator
- Treatment of Rectus Femoris Spasticity: Transfer vs Release
• 1stCerebralPalsyConference,Rizzoli
Institute,Bologna,Italy,Feb2013
- Cerebral Palsy
- Treatment of Hip Disorders in Cerebral Palsy
- Workshop on Femoral Osteotomies
in Cerebral Palsy
• AucklandPediatricOrthopedicSurgery
Symposium, Auckland, NZ, April 2013
- Update on Advances in Cerebral
Palsy and Sports Medicine
• Sydney Pediatric Orthopedic Review,
Sydney, NSW, Australia, April 2013
- Gait Analysis for Dummies
- Aetiology and Classification of Cerebral Palsy
- Case reviews of patients with Cerebral Palsy
• PediatricOrthopedicSocietyofNorth
America, Toronto, Ontario, Canada,
May 2013
42
- Treatment of Patellofemoral Instability in Adolescents
- Section Director of Neuromuscular
and Lower Extremity Specialty Day
- Treatment of GMFCS III Cerebral
Palsy
Peter O. Newton, MD
• President of the Pediatric Orthopedic
Society of North America (POSNA);
May 2012-May 2013
• Basic Science Award Paper, 3D Visualization Of The Vertebral Growth Plate:
The Effects Of Growth Modulation.
Newton, Doan, Glaser, Farnsworth.
Pediatric Orthopedic Society of North
America (POSNA) Annual Meeting,
Toronto, CA, May 2013
Symposium, Orlando, FL, December
8-10,2011
- Surgical Treatment of High Grade
Spondylolisthesis
- Surgical Site Infection Project at Rady
Children’s Hospital San Diego
• PediatricOrthopaedicSocietyofNorth
America Specialty Day. AAOS Meeting,
San Francisco, CA, February 11, 2012
- Technique Update: Vertebral Column
Resection
• 19th Annual Meeting of the Iranian
Orthopedic Association, Tehran, Iran,
October 17-21,2011
- Early Onset Scoliosis
• 25th Annual Meeting of Association of
Spinal Surgeons in India, February 24,
2012
- Early Onset Scoliosis: Surgical Treatment
- Preventing Neurologic Complication
in Spondylolisthesis Surgery
• PeertoPeerDeformity:StrategyofEOS,
Beijing,China,April22,2012
- Key Note lecture, Challenges in EOS
BurtYaszay,MD
• SRS outcome scores are sensitive to
both the occurrence and resolution of
a complication in the surgical treatment of AIS. SRS, September 2012
(Poster, Goldstein Award Nominee)
• Lenke 1C and 5C spinal deformities
fused selectively: A natural history
of uninstrumented compensatory
curves. POSNA, May 2012 (Oral,
Clinical Award Nominee)
• Determining optimal post-operative
•
•
•
•
coronal parameters for selective thoracic fusion. POSNA, May 2013
Better understanding postoperative
changes in adolescent idiopathic scoliosis using 3D reconstructions. AAOS,
March 2013
- What do coronal flexibility films
really tell us about the treatment
of idiopatic early onset scoliosis
patients using growing rods? ICEOS,
November 2012
- EOS-Imaging is available for early-onset scoliosis patients and can
reduce their ionizing radiation
exposure
-Biomechanical evaluation of 4 different foundation constructs commonly
used in growing spine surgery: are rib
anchors comparable to spine anchors
- Limited anterior spinal fusion: an
effective strategy in controlling progressive early onset scoliosis
- Recommendations for patients and
families after growing rod surgery:
surgeon agreement on post-operative care
Selective thoracic fusion in adolescent
idiopathic scoliosis curves with a c
lumbar modifier: which rules can be
broken? SRS, September 2012
- The prevalence of postoperative pain
in adolescent idiopathic scoliosis
and the association with preoperative pain
- Wound infections after spine deformity correction cerebral palsy: risk
factors
- Surgical Outcomes in Adolescent
Idiopathic Scoliosis with or without
spondylolisthesis
Analyzing the relationship between
apical vertebral rotation and truncal
rotation in AIS using 3D reconstructions. IMAST, July 2012
-Better understanding postoperative
changes in adolescent idiopathic
scoliosis using 3D reconstructions of
2D radiographs
- Longitudinal analysis of radiation
exposure during the course of growing rod treatment for early onset
scoliosis
Lenke 1C and 5C spinal deformities
fused selectively: A natural history
1/23/14 4:45 PM
of uninstrumented compensatory
curves. POSNA, May 2012
• Should shoulder balance determine
proximal fusion levels in patients with
Lenke 5 curves? AAOS February 2012
- Are thoracic curves with a low apex
(T11orT11/12)reallythoraciccurves?
- Restoring thoracic kyphosis during
posterior instrumentation for adolescent idiopathic scoliosis
Eric W. Edmonds, MD
• HonoraryMember,ASociedadeBra-
sileira de Ortopedia Pediátrica, 2013
South America Traveling
Fellowship, Pediatric Orthopaedic
Society of North America, 2011
POSNA Biomet South American
Traveling Fellowship, 2011
HonoraryMember,ASociedadeBrasileira de Ortopedia Pediátrica, 2013
Fellow, South America Traveling
Fellowship, Pediatric Orthopaedic
Society of North America, 2011
POSNA Biomet South American
Traveling Fellowship 2011
2013 Annual Meeting of the American Orthopedic Society of Sports
Medicine, Chicago, IL
- Normal Parameters of Skeletally
Immature Knees: Developmental
Changes on Magnetic Resonance
Imaging
2013AnnualMeetingofthePediatric
Orthopaedic Society of North America, Toronto, Canada
- Results Of Displaced Tibial Spine
Fractures: A Comparison Between
Open, Arthroscopic, And Closed
Management
2012AmericanAcademyofPediatrics
National Conference and Exhibition
in New Orleans, LA
- Elbow Fractures in Childhood Obesity: Lateral Condyle vs Supracondylar
Humerus Fractures
2012 Annual Meeting of the Association of Bone and Joint Surgeons,
Charleston, SC
- Contemporary imaging for tibial tubercle fracture patterns in adolescents: Need
for intra-articular assessment
2012AnnualMeetingofthePediatric
Orthopaedic Society of North America, Denver, CO
• Fellow,
•
•
•
•
•
•
•
•
•
- Management Of Rotator Cuff Tears
In Adolescents: Factors Affecting
Patient Outcomes
- Risk Factors for Compartment
Syndrome After Flexible Nailing of
Pediatric Tibial Shaft Fractures
• 2012AnnualMeetingoftheAmerican
Academy of Orthopaedic Surgeons,
San Francisco, CA
- Adolescent rotator cuff tears
- Immediate Intramedullary Flexible
Nailing of Open Pediatric Tibial Shaft
Fractures. Determining Displacement in Medial Epicondyle Humerus
Fractures.
- Effects Of Surgical Treatment for
Recurrent Patella Instability in Adolescent Patients On Knee Extensor
Mechanics
• 2011AnnualMeetingofthePediatric
Orthopaedic Society of North America, Montreal, Quebec, Canada
- Children With Anterior Shoulder
Instability: Do Not Underestimate the
Extent of Labral Pathology
•
AndrewT.Pennock,MD
• Pediatric Orthopedic Society of North
America (POSNA) Annual Meeting,
Winner of the James Kasser, MD Outstanding ePoster Award – Spectrum of
Hip Impingement Morphology in Adolescents:AnEOSBasedDouble-Cohort
Study, Clinical Award Paper Nominee:
Salter-Harris II Fractures of the Distal Tibia: Does Surgical Management
Reduce the Risk of Premature Physeal
Closure? Toronto, CA, May 2013
• American Academy of Pediatrics
(AAP) National Conference, Orlando,
FL, October 26-29, 2013
- The Spectrum Of Hip Impingement Morphology in Adolescents and
Young Adults
• InternationalCartilageRepairSociety
(ICRS) Annual Meeting Izmir, Turkey,
September16-18,2013
- Osteochondral Allograft Transplantation of the Knee in the Pediatric and
Adolescent Population
• American Orthopaedic Society for
Sports Medicine (AOSSM) 2013 Annual
Meeting, Chicago, IL, July 11-14, 2013
- Osteochondral Allografts For Knee
Lesions In The Pediatric And Adoles-
•
•
•
•
cent Population. Does one size fit all:
Variation in tibial tubercle trochlear
groove (TTTG) measuements as a function of age, size, and patella instability?
PediatricOrthopaedicSocietyofNorth
America (POSNA) 2013 Annual Meeting, Toronto, Ontario, May 1-4, 2013
- Does Portable Intraoperative Ct Scan
Improve The Quality Of Talocalcaneal
Coalition Resection
- Previously Described Radiographic
Parameters
Of
Femoroacetabular Impingement Are Common In
Asymptomatic Patients
- At What Age Do Cam and Pincer
Morphology Become Apparent: An
Analysis of 225 Pediatric And Adolescent CT Scans?
- Potential Causes of Loss of Reduction in Supracondylar Humerus
Fractures. Arthroscopic Evaluation Of
Meniscus Tear Patterns In Pediatric
And Adolescent Patients
- Functional And Radiographic
Outcomes 1 After Non-Operative
Treatment Of Displaced Adolescent
Clavicle Fractures
- Results Of Displaced Tibial Spine
Fractures: A Comparison Between
Open, Arthroscopic, And Closed
Management
54thAnnualSocietyofMilitaryOrthopaedic Surgeons (SOMOS) Meeting.
Naples, FL. December 10-14, 2012
- The Hips Antero-Superior Labral
Tear with Avulsion of the Rectus
Femoris (HALTAR) Lesion: Does the
SLAP Equivalent in the Hip Exist?
American Academy of Orthopaedic
Surgeons (AAOS) 2013 Annual Meeting, Chicago, IL, March 19-23, 2013
- Does Surgical Management Reduce
the Risk of Premature Physeal Closure in
Salter-Harris II Distal Tibia Fractures?
International Society for Hip Arthroscopy (ISHA) Annual Scientific Meeting.
Boston,MA,September24-26,2012
- Cam pathology in pediatric patients
InternationalCartilageRepairSociety
(ICRS) Annual Meeting. Montreal,
Canada, May 12-15, 2012
- Comprehensive Arthroscopic Management (CAM) Survivorship: Alternative
to Arthroplasty in Active Patients with
Advanced Shoulder Osteoarthritis
43
1/23/14 4:45 PM
PUBLICATIONS
Chambers H, Shea K, Carey J. AAOS
Clinical Practice Guideline: Diagnosis and treatment of osteochondritis
dissecans. J Am Acad Orthop Surg,
19(5):307-9, 2011.
Clements D, Marks M, Newton P, Betz
R, Lenke L, Shufflebarger H, Harms
Study Group. Did the Lenke classification change scoliosis treatment? Spine
(Phila Pa 1976), 36(14):1142-5, 2011.
Newton P, Farnsworth C, Upasani V,
Chambers R, Varley E, Tsutsui S.
Effects of intraoperative tensioning
of an anterolateral spinal tether on
spinal growth modulation in a porcine model. Spine (Phila Pa 1976),
36(2):109-17, 2011.
Edmonds E. No difference in improvement in physical function between
splint and cast at 6 weeks in children
with minimally angulated fractures
of the distal radius. Evid Based Med,
16(2):49-50, 2011.
Hosalkar H, Wenger D. Nonaccidental
trauma in children: editorial comment.
Clin Orthop Relat Res, 469(3):751-2,
2011.
DalalA,UpasaniV,BastromT,YaszayB,
Shah S, Shufflebarger H, Newton P.
Apical vertebral rotation in adolescent
idiopathic scoliosis: comparison of
uniplanar and polyaxial pedicle screws.
J Spinal Disord Tech, 24(4):251-7, 2011.
Chambers H, Shea K, Anderson A,
BrunelleT,CareyJ,GanleyT,Paterno
M, Weiss J, Sanders J, Watters W 3rd,
Goldberg M, Keith M, Turkelson C,
WiesJ,RaymondL,BoyerK,Hitchcock
K,AndersonS,SlukaP,BooneC,Patel
N, American Academy of Orthopedic
Surgeons. Diagnosis and treatment of
osteochondritis dissecans. J Am Acad
Orthop Surg, 19(5):297-306, 2011.
Mubarak S, Dimeglio A. Navicular excision and cuboid closing wedge for
severe cavovarus foot deformities: a
salvage procedure. J Pediatr Orthop,
31(5):551-6, 2011.
Newton P, Farnsworth C, Upasani V,
Chambers R, Yoon S, Firkins P. Dual
and single memory rod construct
comparison in an animal study. Spine
(Phila Pa 1976), 36(14):E904-13, 2011.
Moraleda L, Mubarak S. Flexible flatfoot:
Differences in the relative alignment of
44
each segment of the foot between symptomatic and asymptomatic patients. J
Pediatr Orthop,31(4):421-8,2011.
PandyaN,BaldwinK,KamathA,Wenger
D, Hosalkar H. Unexplained fractures:
Child abuse or bone disease? A systematic review. Clin Orthop Relat Res,
469(3):805-12,2011.
Price C, Thompson G, Wenger D. Containment methods for treatment of
Legg-Calvé-Perthes disease. Orthop
Clin North Am, 42(3):329-40, 2011.
Gannotti ME, Minter CL, Chambers HG,
Smith PA, Tylkowski C. Self-concept
of adults with cerebral palsy. Disabil
Rehabil, 33(10):855-61,2011.
Smith L, Lee K, Ward S, Chambers H,
Lieber R. Hamstring contractures in
children with spastic cerebral palsy
result from a stiffer extracellular matrix
and increased in vivo sarcomere length.
J Physiol,589(Pt10):2625-39,2011.
Takahashi J, Newton P, Ugrinow V, Bastrom T. Selective thoracic fusion in
adolescent idiopathic scoliosis: Factors
influencing the selection of the optimal
lowest instrumented vertebra. Spine
(Phila Pa 1976), 36(14):1131-41, 2011.
Mubarak SJ, Dimeglio A. Navicular excision and cuboid closing wedge for
severe cavovarus foot deformities: a
salvage procedure. J Pediatr Orthop.
31(5):551-6, 2011.
Price CT, Thompson GH, Wenger DR.
Containment methods for treatment
of Legg-Calvé-Perthes disease. Orthop
Clin North Am. 42(3):329-40, 2011, vi.
Review.
Tsutsui S, Pawelek JB, Bastrom TP, Shah
SA, Newton PO. Do discs “open” anteriorly with posterior-only correction of
Scheuermann’s kyphosis? Spine (Phila
Pa1976).36(16):E1086-92,2011.
Upasani VV, Farnsworth CL, Chambers
RC, Bastrom TP, Williams GM, Sah
RL, Masuda K, Newton PO. Intervertebral disc health preservation after
six months of spinal growth modulation.JBoneJointSurgAm.2011Aug
3;93(15):1408-16.
Yaszay B, O’Brien M, Shufflebarger
HL, Betz RR, Lonner B, Shah SA,
Boachie-AdjeiO,CrawfordA,LetkoL,
Harms PJ, Gupta MC, Sponseller PD,
Abel MF, Flynn J, Macagno A, Newton
PO. Efficacy of Hemivertebra Resec-
tion for Congenital Scoliosis (CS): A
Multicenter Retrospective Comparison
of Three Surgical Techniques. Spine
(Phila Pa 1976). 2011 Sep 8. [Epub
ahead of print].
Wenger DR, Pandya NK. A brief history
of Legg-Calvé-Perthes disease. J Pediatr Orthop. 31(2 Suppl):S130-6, 2011.
Review.
Wenger DR, Pandya NK. Advanced containment methods for the treatment of
Perthes disease: Salter plus varus osteotomy and triple pelvic osteotomy. J
Pediatr Orthop, 31(2 Suppl):S198-205,
2011. Review.
Cidambi KR, Glaser DA, Bastrom TP,
Nunn TN, Ono T, Newton PO. Postoperative changes in spinal rod contour
in adolescent idiopathic scoliosis: an in
vivo deformation study. Spine (Phila Pa
1976),15;37(18):1566-72,2012.
Glaser DA, Doan J, Newton PO. Comparison of 3-dimensional spinal
reconstruction accuracy: biplanar
radiographs with EOS versus computed tomography. Spine (Phila Pa
1976), 37(16):1391-7, 2012.
Franko OI, Bray C, Newton PO. Validation of a scoliometer smartphone app
to assess scoliosis. J Pediatr Orthop.
2(8):e72-5,2012.
Sanders JO, Newton PO, Browne RH,
HerringAJ:Bracinginadolescentidiopathic scoliosis, surrogate outcomes,
and the number needed to treat. J Pediatr Orthop, 32 Suppl 2:S153-7, 2012.
OnoT,BastromTP,NewtonPO.Defining
2 components of shoulder imbalance:
clavicle tilt and trapezial prominence.
Spine (Phila Pa 1976), 37(24) E1511-6,
2012.
NewtonPO,BastromTP,EmansJB,Shah
SA, Shufflebarger HL, Sponseller PD,
Sucato DJ, Lenke LG. Antifibrinolytic agents reduce blood loss during
pediatric vertebral column resection
procedures. Spine (Phila Pa 1976).
37(23) E1459-63, 2012.
MiyanjiF,SlobogeanGP,SamdaniAF,Betz
RR,ReillyCW,SlobogeanBL,Newton
PO. Is larger scoliosis curve magnitude
associated with increased perioperative health-care resource utilization?: a
multicenter analysis of 325 adolescent
idiopathic scoliosis curves. J Bone Joint
Surg Am,94(9):809-13,2012.
1/23/14 4:45 PM
LiuRW,YaszayB,GlaserD,BastromTP,
Newton PO. A method for assessing
axial vertebral rotation based on differential rod curvature on the lateral
radiograph. Spine (Phila Pa 1976),
37(18)E1120-5,2012.
Hosalkar HS, Pennock AT, Zaps D,
Schmitz MR, Bomar JD, Bittersohl B.
The hip antero-superior labral tear with
avulsion of rectus femoris (HALTAR)
lesion: does the SLAP equivalent in the
hip exist? Hip Int, 22(4):391-6, 2012.
Philippon MJ, Pennock A, Gaskill TR.
Arthroscopic reconstruction of the
ligamentum teres: technique and
early outcomes. J Bone Joint Surg Br,
94(11):1494-8,2012.
Gottschalk HP, Eisner E, Hosalkar HS.
Medial epicondyle fractures in the
pediatric population. J Am Acad
Orthop Surg, 20(4):223-32, 2012.
BaldwinK,HsuJE,WengerDR,Hosalkar
HS. Treatment of femur fractures in
school-aged children using elastic stable intramedullary nailing: a systematic
review. J Pediatr Orthop B,20(5):303-8,
2011. Review.
Hosalkar HS, Varley ES, Glaser DA, Farnsworth CL, Wenger DR. Intracapsular
hip pressures in a porcine model: does
position and volume matter? J Pediatr
Orthop B,20(5):278-83,2011.
Pennock AT, Pennington WW, Torry MR,
Decker MJ, Vaishnav SB, Provencher
MT, Millett PJ, Hackett TR. The influence of arm and shoulder position on
the bear-hug, belly-press, and lift-off
tests: an electromyographic study. Am J
Sports Med,39(11):2338-46,2011.
Hosalkar HS, Varley ES, Glaser D, Farnsworth CL, Bomar JD, Wenger DR.
Isocentric reattachment of ligamentum
teres: a porcine study. J Pediatr Orthop.
31(8):847-52,2011.
Zaltz I, Hosalkar H, Wenger D. What’s new
in pediatric orthopaedic surgery. J Bone
Joint Surg Am, 94(4):375-81,2012.
HosalkarH,MunhozdaCunhaAL,Baldwin K, Ziebarth K, Wenger DR. Triple
innominate osteotomy for Legg-Calvé-
Perthes disease in children: does the
lateral coverage change with time? Clin
Orthop Relat Res. 2470(9):2402-10, 2012.
Gjolaj JP, Sponseller PD, Shah SA, Newton
PO, Flynn JM, Neubauer PR, Marks
MC, Bastrom TP. Spinal deformity
correction in Marfan syndrome versus
adolescent idiopathic scoliosis: learning from the differences. Spine (Phila
Pa1976),37(18)1558-65,2012.
Cho RH, Yaszay B, Bartley CE, Bastrom
TP, Newton PO. Which Lenke 1A
curves are at the greatest risk for adding-on... and why? Spine (Phila Pa
1976),37(16)1384-90,2012.
Bittersohl B, Hosalkar HS, Wenger DR.
Surgical treatment of hip dysplasia in
children and adolescents. Orthop Clin
North Am, 43(3):301-15, 2012.
Samdani AF, Hwang SW, Miyanji F, Lonner
B,MarksMC,SponsellerPD,Newton
PO, Cahill PJ, Shufflebarger HL, Betz
RR. Direct vertebral body derotation,
thoracoplasty, or both: which is better
with respect to inclinometer and sco-
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liosis research society-22 scores? Spine
(PhilaPa1976),37(14)E849-53,2012.
Lonner BS, Lazar-Antman MA, Sponseller PD, Shah SA, Newton PO, Betz
R, Shufflebarger HS. Multivariate
analysis of factors associated with
kyphosis maintenance in adolescent
idiopathic scoliosis. Spine (Phila Pa
1976), 37(15):1297-302, 2012.
Sponseller PD, Jain A, Lenke LG, Shah
SA, Sucato DJ, Emans JB, Newton
PO. Vertebral column resection in
children with neuromuscular spine
deformity. Spine (Phila Pa 1976),
37(11) E655-61, 2012.
Sponseller PD, Flynn JM, Newton PO,
MarksMC,BastromTP,Petcharaporn
M, McElroy MJ, Lonner BS, Betz RR.
Harms Study Group: The association
of patient characteristics and spinal
curve parameters with Lenke classification types. Spine (Phila Pa 1976),
37(13)1138-41,2012.
Dhawale AA, Shah SA, Sponseller PD,
BastromT,NeissG,YorgovaP,Newton
PO, Yaszay B, Abel MF, Shufflebarger
H, Gabos PG, Dabney KW, Miller F.
Are antifibrinolytics helpful in decreasing blood loss and transfusions during
spinal fusion surgery in children with
cerebral palsy scoliosis? Spine (Phila Pa
1976), 37(9)ES49-55, 2012.
Marks M, Newton PO, Petcharaporn M,
Bastrom TP, Shah S, Betz R, Lonner
B, Miyanji F. Postoperative segmental
motion of the unfused spine distal to
the fusion in 100 patients with adolescent idiopathic scoliosis. Spine (Phila
Pa1976),37(10)826-32,2012.
Hwang SW, Samdani AF, Lonner B,
MiyanjiF,StantonP,MarksMC,Bastrom T, Newton PO, Betz RR, Cahill
PJ. Impact of direct vertebral body
derotation on rib prominence: are preoperative factors predictive of changes
in rib prominence? Spine (Phila Pa
1976),37E86-9,2012.
Akbarnia BA, Mundis GM Jr, Salari P,
Yaszay B, Pawelek JB: Innovation in
growing rod technique: a study of
safety and efficacy of a magnetically
controlled growing rod in a porcine
model. Spine (Phila Pa 1976), 7(13)
E86-9,2012.
Moraleda L, Salcedo M, Bastrom TP,
Wenger DR, Albiñana J, Mubarak
46
SJ. Comparison of the calcaneo-cuboid-cuneiform
osteotomies
and the calcaneal lengthening osteotomy in the surgical treatment of
symptomatic flexible flatfoot. J Pediatr
Orthop,32(8):821-9,2012.
Pandya NK, Edmonds EW, Roocroft JH,
Mubarak SJ. Tibial tubercle fractures:
complications, classification, and the
need for intra-articular assessment. J
Pediatr Orthop, 32(8):749-59,2012.
Dutton P, Edmonds EW, Lark RK, Mubarak
SJ. Prevalence of painful peroneal
tubercles in the pediatric population.
J Foot Ankle Surg, 51(5):599-603, 2012.
Wenger DR, Hosalkar HS. Principles of
treating the sequelae of Perthes disease.
Orthop Clin North Am, 42(3):365-72,
vii, 2011.
Podeszwa DA, Mubarak SJ. Physeal fractures of the distal tibia and fibula
(Salter-Harris Type I, II, III, and IV
fractures). J Pediatr Orthop, 32 Suppl
1:S62-8,2012.
Edmonds EW, Roocroft JH, Mubarak SJ.
Treatment of displaced pediatric supracondylar humerus fracture patterns
requiring medial fixation: a reliable and
safer cross-pinning technique. J Pediatr
Orthop, 32(4):346-51, 2012.
Gantsoudes GD, Roocroft JH, Mubarak SJ.
Treatment of talocalcaneal coalitions. J
Pediatr Orthop, 32(3):301-7, 2012.
Chang RF, Mubarak SJ. Pathomechanics of
Gowers’ sign: a video analysis of a spectrum of Gowers’ maneuvers. Clin Orthop
Relat Res, 470(7):1987-91,2012.
Wenger DR. Limitations of evidence-based
medicine: the role of experience and
expert opinion. J Pediatr Orthop, 32
Suppl2:S187-92,2012.
Smith LR, Chambers HG, Subramaniam S,
Lieber RL. Transcriptional abnormalities of hamstring muscle contractures in
children with cerebral palsy. PLoS One,
7(8):e40686,2012.doi:10.1371/journal.
pone.0040686.Epub2012Aug16.
Chambers HG, Shea KG, Anderson AF,
JojoBrunelleTJ,CareyJL,GanleyTJ,
Paterno M, Weiss JM, Sanders JO, Watters WC 3rd, Goldberg MJ, Keith MW,
Turkelson CM, Wies JL, Raymond
L, Boyer KM, Hitchcock K, Sluka P,
BooneC,PatelN,AmericanAcademy
of Orthopaedic Surgeons. American
Academy of Orthopaedic Surgeons
clinical practice guideline on: the
diagnosis and treatment of osteochondritis dissecans. J Bone Joint Surg Am,
18;94(14):1322-4,2012.
TisJE,EdmondsEW,BastromT,Chambers HG. Short-term results of
arthroscopic treatment of osteochondritis dissecans in skeletally immature
patients. J Pediatr Orthop, 32(3):22631, 2012.
ChambersHG, BeckerRE,HoffmanMT,
Hartley-McAndrew M, Stein MT.
Managing Behavior for a Child with
Autism in a Body Cast. J Dev Behav
Pediatr,33:506-508,2012.
Smith LR, Chambers HG, Lieber RL.
Reduced Satellite Cell Population May
Lead to Contractures in Children with
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47
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Pediatric
Otolaryngology
The Division of Pediatric Otolaryngology at Rady Childrens
Specialists of Diego (RCSSD) manages complex tertiary care
otolaryngologic disorders, including: congenital and acquired
hearing loss in children; airway problems ranging from
obstructive sleep apnea to complicated diseases of the laryngeal
and tracheal airway requiring cutting edge surgical intervention
and reconstruction; complications of acute sinusitis that involve
the eye and brain; chronic sinusitis problems in children
including those with cystic fibrosis; congenital abnormalities of
the face and neck, including complex vascular malformations;
congenital and acquired thyroid disease; and a host of
communication, speech and voice disorders. The Division also
leads a variety of interdisciplinary teams, including the Pediatric
Airway and Aerodigestive Team, Cochlear Evaluation and
Implementation Team, and Voice Disorders in Children and
Thyroid Tumor Board.
All of the physicians in the Division are fellowship trained
in pediatric otolaryngology, which requires completion of an
otolaryngology residency, plus a minimum of one additional
year of specialty training. This advanced training is focused
completely on the unique diagnostic and treatment issues in
children from birth to 19 years of age.
The Division of Pediatric Otolaryngology has been a
source of leadership and innovation for over 30 years. With its
commitment to ongoing patient care, physician education and
research at the highest of levels, the Division will continue to
enhance its expertise and devotion to state-of-the-art therapy
for children with hearing and speech impairment, infectious
diseases of the head and neck, and complex airway and head
and neck abnormalities.
otolaryngology v5.indd 48
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FACULTY
Seth M. Pransky, MD, Director, Division
of Pediatric Otolaryngology; Director,
Satellite Services RCHSD; Clinical
Professor of Surgery, UCSD
Marcella Bothwell, MD, Director,
Pediatric Airway and Aerodigestive
Team, RCHSD; Clinical Professor of
Surgery, UCSD
Daniela S. Carvalho, MD, Section Chief,
Otolaryngology-RCHSD; Director,
Hearing Program; Director, Pediatric
Otolaryngology Fellowship Program;
Clinical Professor of Surgery, UCSD
Wen Jiang, MD, Director, Pediatric
Thyroid Clinic; Co-Director Speech
and Voice Clinic; Assistant Clinical
Donald B. Kearns, MD, Chief Medical
Officer-RCHSD; Clinical Professor of
Surgery, UCSD
Shelby Leuin, MD, Director, ENT Resident Training Program; Co-Director
Speech and Voice Clinic; Assistant
Anthony Magit, MD, Director, Inpatient
Surgical Services, RCHSD; Director,
Institutional Review Board-RCHSD;
Denise Lago, PAC
Pam Salgado, PAC
CLINICAL ACTIVITIES
The Division’s physicians are responsible
for covering the Emergency Department
at RCHSD and running the Consultation
Service for patients admitted to the hospital with ear, nose, throat, airway and
neck abnormalities. The bulk of clinical
practice is carried out on the campus of
RCHSD combined with daily patient
activity at satellite locations in Encinitas, Escondido Murrieta, and Oceanside.
In addition, consultative services are
provided to multiple regional Neonatal
Intensive Care facilities including Sharp
Mary Birch, Scripps La Jolla, Scripps
Encinitas and UCSD Medical Center.
Patients requiring operative intervention or specialized testing are brought to
RCHSD. From 2011-2013 the Division
conducted over 45,000 patient visits and
carried out approximately 9000 operative
procedures. Procedures included:
• Placing ear tubes, removing tonsils
and adenoids, restoring hearing with
ossicular reconstruction, and the state
of the art cochlear implant and Bone
Anchored Hearing Aid program
• Diagnostic and therapeutic endoscopic
airway procedures from neonates to
adolescents and open surgical management of complex airway diseases
• Endoscopic sinus surgery for children
with chronic sinusitis and complications of acute sinusitis; management
of various intranasal abnormalities
including turbinate malformations,
septal deviations, bony nasal deformities, and open rhinoplasty for complex
nasal obstruction and nasal tumors;
management of the nasal and sinus
manifestations of cystic fibrosis
LEFT TO RIGHT:
Daniela Carvalho,
Wen Jiang, Seth
Pransky, Marcella
Bothwell, Anthony
Magit, Shelby Leuin
Pediatric Otolaryngology
49
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• Surgicalcorrectionofavarietyofcongenital head and neck malformations
and management of both benign and
malignant head and neck neoplasms
with a focus on thyroid abnormalities
and lymphatic malformations
The Divisionrrection of a variety of
congenital head and neck malformations
and management of both benign and
malignant head and neck neoplasms with
a focus on thyroid abnormalities and lymphatic malpapillomatosis attracts patients
from California, Nevada, Arizona, Mexico and the Pacific Rim countries for
specialized pediatric ENT care.
Marcella Bothwell, MD
Marcella joined our department in 2007.
She comes from the University of Missouri, where she was there for 6 years. She
is now a Clinical Professor, Department
of Surgery UCSD and a student at the
Rady School of Management. Biomedical
research is an avid interest for Dr. Bothwell and she has collaborated with the La
Jolla Allergy and Immunology Institute
for research on the etiology of recurrent tonsillitis and the body’s follicular T
helper cell response in hopes of vaccine
development. Because of this partnership, she became very interested in the
ethics of human tissue research and in
2012 wrote an article for the Rady Business Journal with her coauthor and Rady
School of Management Professor Erez
Yoeli, PhD, Biotechnology consult: What
does economics teach us about how to
assign property rights for human tissue?.
At RCHSD she developed and directs
the Pediatric Airway and Aero digestive
Team (PAAT), a multidisciplinary group
that sees about 50 new patients each year
with complex airway, swallowing and
feeding problems. Dr. Bothwell is also
quite active in the regional and national
ENT community where she is Immediate
Past President of the San Diego Academy of Otolaryngology. She is also the
Immediate Past Chair for the ENTPAC
and travels to Washington DC at least 2
times per year to lobby Congress about
concerns in patient care. Finally Marcella
has made three trips to Vietnam with REI
International for a medical/surgical mission trip.
50
Daniela Carvalho, MD
Daniela joined our department in 2003,
having completed a two-year fellowship
with our group from 1999-2001. She has
worked as the Section Chief for Otolaryngology at RCHSD since 2009. Daniela’s
clinical focus and area of interest is hearing in children including sensorineural,
conductive and genetic hearing loss. As
the director of the Hearing Program and
lead surgeon for the RCHSD Cochlear
Implant team, Daniela assesses hearing loss patients and guides the Team in
management of more than 300 cochlear
implant patients. This past year she successfully performed about 40 cochlear
implants, including the most state of the
art implants from three different implant
brands. She continues to bring to our
pediatric hearing-impaired patients
state-of-the-art innovations in the area
of implantable hearing devices, including the BAHA, Ponto-pro and Sophono
devices (she performed the first pediatric
Sophono implant in Southern California). Daniela has been the co-director of
our Pediatric Otolaryngology Fellowship
program and was responsible for successfully having our program accredited by
the ACGME. She is involved in multiple
international endeavors including ongoing lectures in her native Brazil through
the Brazilian National ENT Association
and her role as international liaison for
SENTAC. She is the only female physician who is a member of the International
Working Group on Endoscopic Ear
Surgery. She is also very active in the
American Society of Pediatric Otolaryngology as the chairperson for the Long
Range Strategic Planning Committee..
Wen Jiang, MD
Wen joined our department in 2007 and
was accepted this year as a member to
the American Society of Pediatric Otolaryngology. She continues her head
and neck oncology practice with a special interest in thyroid neoplasms in
children. Together with the department
of Endocrinology, she has created a
multi-disciplinary thyroid tumor board
to discuss the management of patients
with thyroid pathology. She has been
twice awarded the RCHMF physician
development grant to attend the inter-
national American Thyroid Association
meeting and was recently accepted as a
member to the American Thyroid Association. Her listing on the ATA website for
patient referral has put Rady Children’s
hospital on the national map for thyroid
disorders. Currently Wen is finishing an
IRB approved retrospective review of our
institutional experience in thyroidectomy
patients over the last 10 years. A second specialized focus for Dr. Jiang is in
voice disorders in children. She currently
co-directs the Speech and Voice Endoscopy Clinic, a multi-disciplinary voice
and speech team working closely with the
Speech Pathology department at RCHSD.
This team continues to provide comprehensive service to children with speech
related disorders such as hypernasality
and/or velopharyngeal incompetence,
and other voice disorders. Wen has partnered with the emergency department to
prospectively study the accuracy of metal
detectors in detection and localization of
metallic esophageal foreign bodies. The
goal is to utilize metal detectors to minimize radiation exposure and to expedite
the triage of these patients in the emergency room.
Dr. Jiang is the our Division’s medical informatics champion and is currently
heading the effort for our EPIC optimization process to make the overall physician
workflow more efficient while maximizing
the utility of our electronic medical records.
Donald has practiced Pediatric Otolaryngology at RCHSD for 25 years. He
completed the Master of Medical Management program at the Marshall School
of Business at the University of Southern
California in 2008. His primary interest is
in administrative medicine. He currently
serves as the Interim Surgeon in Chief
for RCSSD and is the Chief Medical Officer and Senior Vice President for Health
Affairs for Rady Children’s Hospital San
Diego.
Shelby Leuin, MD
Shelby is the newest addition to the Pediatric Otolaryngology group at RCHSD,
joining the practice in January 2011. She
did her residency training at the Harvard
Combined Otolaryngology Program and
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her pediatric otolaryngology fellowship
training at the University of Colorado,
Denver Children’s Hospital. Her clinical
interests focus on midfacial abnormalities including congenital and acquired
nasal deformities, cleft palate and velopharyngeal insufficiency, as well as airway
anomalies and reconstruction. She adds
a unique skill set to our group with her
training and interest in functional rhinoplasty. She has been awarded two
Physician Development Grants to attend
courses and symposia on rhinoplasty and
has been actively building her practice
in this area. Shelby is co–director of the
Speech and Voice Endoscopy Clinic and
participates actively in the Cleft Palate
and Craniofacial clinics. In this capacity,
she provides the unique ability to provide
continuity of care for these patients by
both performing the office nasal endoscopy in collaboration with the speech
language pathologists as well as performing the speech surgery for velopharyngeal
insufficiency.
On a national level Dr. Leuin has
been selected to be a member of the
American Academy of Otolaryngology
Pediatric Otolaryngology Education
Committee and as such has published
education materials on pediatric sinusitis. Locally, she is collaborating with Jane
Burns, M.D. on a study evaluating the
laryngeal findings associated with hoarseness in children with Kawasaki disease.
The findings have been presented at both
national and international meetings and
have also recently been published.
Dr. Leuin is also the Director of
the Pediatric Otolaryngology residency-training program. She has presented
at Grand Rounds and multiple CME
courses, as well as at morning conference
for the otolaryngology residents. She
actively mentors the group’s Physician
Assistant in publishing and presenting at
several national meetings.
Anthony E. Magit, MD
Anthony has been a part of our group for
19 years. He is currently serving as the
immediate past chief of staff of RCHSD
and is the Chairman of the RCHSD
Institutional Review Board. Anthony’s
ongoing areas of clinical and research
interests include lymphatic malforma52
tions, cystic fibrosis and obstructive
sleep disorders in infants and children.
He continues to collaborate with the Pulmonary Division and has been involved
in investigating a novel approach for
treating patients with lymphatic malformations as well has having treated more
than 160 patients with lymphatic malformations from the Southwestern region of
the United States and Northern Mexico.
Superimposed on a full clinical practice
and his administrative duties, Anthony
is President of the Society for Ear, Nose
and Throat Advances in Children and
earned his Masters in Public Health from
the Johns Hopkins Bloomberg School of
Public Health in May, 2012. Anthony’s
involvement with representing RCHSD
and pediatric medicine include membership on the Board of the San Diego County
Medical Society and the Children’s Specialty Care Coalition.
Seth M. Pransky, MD
Seth began practice at RCHSD in 1985 and
became the Division Director for Pediatric Otolaryngology in 1997. At RCHSD
he is the Director of Satellite Services and
chairs the Clinical Practice Committee
and is the CME Director for the Regional
Practical Pediatrics courses. His ongoing
areas of clinical interest include issues
related to airway diseases and endoscopic
management of these problems,, operative
management of nasal and sinus disease
in children and issues related to tympanostomy tube utilization. He lectures
extensively throughout the United States
and internationally on these and other
topics. In 2008 Seth received the Gabriel
F. Tucker Award from the American Laryngological Association for outstanding
contributions to Pediatric Laryngology. In
2011 he was awarded the prestigious Ray
Skoglund Excellence in Teaching Award
from RCHSD. In 2013 he received the
Chevalier Jackson award from the American Bronchesophagologic Association for
Outstanding Achievement and Accomplishment in Bronchoesophagology, In
addition to his local responsibilities, Seth
has been involved nationally with board
positions in the American Society of Pediatric Otolaryngology and the American
Academy of Pediatrics ENT Section and
was recently the President of the Soci-
ety of Ear, Nose and Throat Advances in
Children.
RESEARCH ACTIVITIES
For the past 28 years, the Division has
been recognized around the world for
innovative research and advancements
in managing a variety of pediatric airway
abnormalities. Procedures include corrective open laryngotracheal reconstruction
and therapeutic endoscopic management
of airway abnormalities using innovative
lasers, debriders and injectable medications. Current research projects involve all
aspects of pediatric otolaryngology including cochlear implant issues, head trauma,
head and neck tumor management in
children, lymphatic malformations treatment, acute and chronic sinusitis research
and outcomes of sinus surgery, and more
unusual problems such as lack of sense of
smell in children, hoarseness in patients
with Kawasaki’s Disease and resolution
of recurrent fever after tonsillectomy in
patients with Periodic Fever, Aphthous
stomatitis, Pharyngitis, Adenitis (PFAPA)
Syndrome. The active research projects are:
• OralLanguageCapabilitiesofMonolingual and Bilingual Spanish and
English Speaking Children with
Cochlear Implants
• Epidemiology of skull base fractures
in San Diego County
• Managementoflymphaticmalformations: A database protocol
• Multi-Institutional study of Picibanil
for Lymphatic Malformations
• SystematicReviewofsinussurgeryin
patients with Cystic Fibrosis
• Anosmiainthepediatricpopulation
• Salivaryglandtumorsinthepediatric
populations
• HoarsenessinKawasakiPatients
• Cellular Immunity in Periodic Fever,
Aphthous stomatitis, Pharyngitis,
Adenitis (PFAPA) Syndrome
• Ten year retrospective review of
orbital complications of acute sinusitis
at RCHSD
• Pharyngeal probe for Extra esophageal reflux
• Prospective assessment of Ankyloglossia and response to Frenulotomy
• Comparison of non-verbal cognitive
function in patients with hearing loss
of various etiologies
1/23/14 4:46 PM
• The Respective Contributions of
Computed Tomography and Magnetic Resonance Imaging in Cochlear
Implant Pre-Operative Planning in
Academic Institutions
• Ten year retrospective review of
thyroid neoplasms in the pediatric
population
• TheroleofmetaldetectorsintheED
for esophageal foreign bodies detection and expedited management
TEACHING ACTIVITIES
Superimposed on clinical care is the
Division of acute sinusitis at RCHSDFAPA) S two fellows in our clinical
Pediatric Otolaryngology fellowship program. Since 1990, we have graduated 29
fully-trained pediatric otolaryngologists
who have gone on to productive careers
in academic institutions throughout the
United States. In addition, the Division is
responsible for educating ENT residents
from the UCSD and the Naval Medical
Center San Diego programs in pediatric otolaryngology. Pediatric residents,
family medicine residents and medical
students and nurse practitioner students
also rotate through the clinic and receive
didactic lectures from our staff as part
of their pediatric specialty education
program. The Division actively participates in community outreach programs
through involvement with the health
professionals mentor program at UCSD
and through its involvement with the
otology and hearing clinic for San Diego
City Schools. Physicians from around the
world enjoy the opportunity for observational preceptorships with physicians
from Brazil, Peru, Mexico, Chile, Venezuela, Vietnam and Iraq having spent
time at RCHSD in recent years. Throughout the year, members of the Division
give Grand Rounds lectures and CME
programs to community-based physicians in multiple specialties to ensure
state-of-the-art practice for primary care
physicians.
On a national level, the Division provides extensive update meetings drawing
primary care physicians from around the
country to review management issues for
a wide range of pediatric ENT problems.
In addition, members of the department
give Instructional Courses each year
at the American Academy of Otolaryngology Annual and at the American
Academy of Pediatrics national meetings.
In 1992, the Division created International Endoscopy Days at RCHSD, a
world class meeting for pediatric otolaryngologists from around the world. The
otolaryngologists participate in a day of
live operative endoscopy followed by
lectures, panels and open discussion on
cutting-edge management of pediatric airway abnormalities. In April 2012
over 125 physicians from around the
world attended the 15th International
Endoscopy day at RCHSD. Four very
challenging live airway endoscopy cases
were performed by our group, observed
by the attendees and spirited discussion,
debate and audience interaction followed.
Once again comments from the attendees
such as “The best conference all yearernational Endoscopy day at RCHSD. Four
The Cochlear Implant
Program at RCHSD
The Cochlear Implant (CI) team at
RCHSD began in 2004 under the directorship of Daniela Carvalho, MD. This
program has been critical in providing
hearing restoration for children with
profound hearing loss that do not benefit
from hearing aids. This mode of hearing
rehabilitation permits these children to
enter into the mainstream community
and achieve their full educational and
communicative potential. Our multidisciplinary team includes hearing and speech
specialists, an auditory verbal therapist,
developmental psychologists and social
workers from RCHSD. The program has
grown steadily and there are more than
450 CI patients followed by our group
and has been a dramatic success as shown
by the growth and accomplishment of the
team listed below.
CI Tean Accomplishments/CI Growth
• 2004: 10 CI surgeries year 2010: 52 CI
surgeries/year FY2012: 30 CI surgeries/
year
• 2007:238CI’sprogrammed/year2011:
420 CI’s programmed/year FY2012:
440 CI’s programmed
• 2004:<100patients
• 2011:>300patients
• FY2012:>400patients
Aural Rehabilitation Services/Providers
• 2004:2SpeechLanguagepathologists
• 2011:9SpeechLanguagepathologists,
including auditory verbal therapist
FY2012: 9 Speech Language pathologists, including auditory verbal therapist
Audiology Services/Providers
• 2004:1CochlearImplantaudiologist
• 2005:3CochlearImplantaudiologists
• 2009:4CochlearImplantaudiologists
• 2011:5CochlearImplantaudiologists,
one of whom is bilingual and one who
has a cochlear implant
• FY2012: 4 Cochlear Implant audiologists, one who has bilateral cochlear
implants
PRESENTATIONS/
RESEARCH
• Poster–Unresponsiveness to bilateral
cochlear implantation on an otherwise healthy deaf child. SENTAC 2005
• Poster–Possiblehormonal-inducedauditory symptoms in pediatric cochlear
implant patients. ASPO 2007
• Poster–Howdoelectricalstapedialreflexes
compare with neural response telemetry?
International Pediatric Cochlear Implant
Meeting 2007
• Poster–Comparisonofpediatriccochlear
implant patients from a developed and a
developing country. International Pediatric Cochlear Implant Meeting 2007
• Poster–Routine assessment indicates
appropriate hearing aid benefit: Can
we do better? International Pediatric
Cochlear Implant Meeting 2008
• Poster–Bimodal-ism: Does frequency
transposition technology have a role?
International Pediatric Cochlear Implant
Meeting 2009
• Poster–The fine line for indication of
hearing aids versus cochlear implants:
Can we do better? ASPO 2009
• Poster–Distortionsinpubescentcochlear
implant patients: Real or phenomenon?
AAA 2010
• NeedlemanA,RoseH.CochlearImplant
Candidacy: What are the Determinants? Paper presented at the American
Speech-Language-Hearing Association
annual meeting. San Diego, CA, 2011
53
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• IRB approval: Oral Language Capabilities of Monolingual and Bilingual
Spanish and English Speaking Children
with Cochlear Implants (Carvalho D.
principal investigator), 2011
• Needleman A, Rose H. Candidacy
Determinants for Pediatric Cochlear
Implantation. Paper presented at the
American Academy of Audiology
annual AudiologyNOW! Conference.
Boston, MA, 2012
• Rose H, Hu M, Mellish A. It Takes a
Village. Paper presented at the Alexander Graham Bell Biennial Meeting.
Denver, CO, 2012
• Carvalho D, Needleman A, Rose H.
Pediatric Cochlear Implant Candidacy: What are the Best Evaluation
Tools? Paper presented at the Society
for Ear, Nose and Throat Advances in
Children (SENTAC) Annual Meeting.
Charleston, SC, 2012
• ListeningandSpokenLanguageTechniques: From Birth to High School.
Full day conference put on by RCHSD
focusing on listening and spoken language techniques for working with
children with cochlear implants. San
Diego, CA, 2013
Community/Family Outreach
• Joyofsound
• Parentworkshops
2009: 4 parent workshops
2010: 3 parent workshops
• Teengroup
• Spanishtoddlergroup
• 2009: Cochlear implant team logo
created
• 2009: cochlear implant program
brochure
• 2010:Cochlearimplantvideocreated
• 2012: Development of Audiologist
& Speech Pathologist sessions for
co-treating children who are not
progressing as expected with their
cochlear implants. The collaboration
between speech pathologists and audiologists is resulting in more accurate
program maps in the speech processors, leading to better functional
hearing, and ultimately improved
speech and language development
• 2012: Trained the Cajon Valley early
intervention, pre-school and elementary public school teachers of the deaf,
54
and speech pathologists, in the Auditory Verbal approach to intervention.
• 2013:Music&LiteracyRoomcreated
Community Education and Training
• Speech Language Pathology Mentor
Program: 3-4x/year
• Educationalsitevisits,2x/year:Deafand
hard of hearing center based programs
- Lafayette Elementary
- Whitman Elementary
- Reidy Creek Elementary
- Davila Day School
- Magnolia Elementary
• February2008:EducatorsWorkshop–
Connecting care for children with
cochlear implants: From the clinic to
the classroom
• 2009: RCHSD Workshop–Improving
early identification of hearing loss
• May 2011: El Centro Workshop–
Cochlear implants and outcomes
• August 2011: El Centro Outreach–
Best practices in cochlear implants
• 2012: Began parent education series
that Heather Rose (AVT) presents
monthly at the Ora Lingua School for
children with hearing impairments
Community Philanthropic Support
• 2010: Auxiliary–Fuerte Hills Unit
Sweet Charity Event: $36,395 to support comprehensive developmental
evaluations, multidisciplinary case
conferences, post implant therapies
(AVT), and speech and language
evaluations
• June 2010: $500,000.00 gift pledge
from Shirley and Sam Richter to support the Cochlear Implant Program
AWARDS, HONORS AND
MAJOR PRESENTATIONS
Marcella Bothwell, MD
• The International Women’s Leadership Association
Woman of Outstanding Leadership
Award 2013
• Rady School of Management Fellowship Award
• NationalPractitionerExcellenceAward
from Board of Governors American
Academy of Otolaryngology 2011
• Consumer’sResearchCouncil,America’s Top Physicians 2009, 2010, 2011,
2012, and 2013
• Physician Development Award, Rady
Children’s Foundation, 2010
National/Regional Society Activities
• San Diego Academy of Otolaryngology HNS– Immediate Past President
• California Otolaryngology Society–
Board of Directors
• AmericanAcademyofOtolaryngology–
ENTPAC Board of Directors
• Public Relations committee of the
• AmericanAcademyofOtolaryngology/
Head and Neck Surgery (AAO.HNS)
Millennium Society Life Member
• RadySchoolofManagementWireless
Health Club Chief Operating Officer
2013 – present
Rady Childrens ENTPAC Committee
• Pediatric Airway and Aerodigestive
Team, Chair, RCHSD
• IndicationsandTechniquesforPediatric Tracheostomy. Tracheostomy Day,
RCHSD, San Diego, CA, August 2009
Television, Radio and Newspaper
• Hearingloss/NoiseExposure,Women’s Health July, 2013
• Ear Wax is nature’s Defense against
Objects and Infections, Union Tribune, May 15, 2012
• San Diego Union Tribune UTTV
Internet Addiction Fact or Fiction?
September 3, 2013
Autism the Real Story August 27, 2013
• SanDiegoUnionTribuneUTTVVaccines Save Lives August 20, 2013
• SanDiegoUnionTribuneUTTVSummer Sunscreen Advice July 2, 2013
Hearing 2013 June 25, 2013
HPV Vaccine June 20,2013
• SanDiegoUnionTribuneUTTVKids
Access to Marijuana, June 4, 2013
• SanDiegoUnionTribuneUTTVOral
Cancer HPV Risks Parts One and
Two, June 3, 2013
Sports Fractures, April 9, 2013
Scary Food Additives, March 5, 2013
1/23/14 4:46 PM
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
Women Versus Men in Sports, February 26, 2013
SanDiegoUnionTribuneUTTVProbing ‘Roid’ Rage, February 19, 2013
San Diego Union Tribune UTTV
Obesity Myth February 5, 2013
Essence of Anti Oxidants January 29,
2013
Doctor weighs in on Lance Armstrong, January 17, 2013
SanDiegoChannel6,“Beforeandafter
you have the flu” what are the best tips
to getting better?, January 15, 2013
SanDiegoUnionTribuneUTTVDanger of Energy Drinks, January 8, 2013
SanDiegoUnionTribuneUTTVTruth
About Blood Clots, January 1, 2013
Chronic Traumatic Encephalopathy
in Football players December 4, 2012
SanDiegoUnionTribuneUTTV2012
Influenza Season, December 2, 2012
Dangerous Toys of Store Shelves
Press Conference at Rady Childrens’
Hospital Multiple Local stations and
Interview Channel 10, November 26,
2012
San Diego CW, Personal Music Players and Hearing Loss
San Diego New 7 NBC, Personal
Music Players and Hearing Loss
ChokingandLocalChild’sDeath,San
Diego NBC News, August, 2011
Choking and Children, San Diego
KIUS News, February 22-23, 2010
Bucky Balls and Ingestion Risk, San
Diego CW News, Spring 2011
Button Battery Ingestion Risk, San
Diego Telemundo News, 2010
Daniela Carvalho, MD
•
•
•
•
•
America’sTopPhysicians2013
BestDoctorsinAmerica2009,2011
RCHSDBesttoListenToAward2009
SanDiegoSuperDoctors,2011
Second place, Clinical category, for
the Poster: Survey of thyroglossal duct
cyst in a subspecialty referral practice. 24th Annual ASPO (American
Society of Pediatric Otolaryngology)
Meeting, Seattle, WA, May 2009
• Third place for the poster “The
Parental Perception Of Vestibular
Impairments In Pediatric Cochlear
Implant Patients”, SENTAC (Society
Children) 39th Annual Meeting, Kansas City, MO, December, 2011
National/International
Society Activities
Implantable Hearing Aid Devices Committee, 2009-current
American Society of Pediatric Otolaryngology Chairperson: Long Range/Strategic
Planning Committee, 2012-2015
Society for Ear, Nose and Throat Advances
in Children Member: Liaison Committee, 2009-2010; Chairperson,
Liaison Committee, 2010-current
• BrazilianAssociationofOtolaryngology, Head-Neck-Facial Surgery
• Member, International Committee,
2009-2010
• Member, Educational Committee,
2009-2010
• International Working Group on
Endoscopic Ear Surgery
• Correspondingmember,2010
• Section Chief of Otolaryngology,
2009-current
Rady Children’s Specialists of San
Diego, A Medical Foundation
• ContractsCommittee
• PhysicianRetentionCommittee
Community
JCCNiermanPreschoolHealth&Safety
Committee (2009-2010)
Scientific Presentations
Cellular Immunity in Periodic Fever,
Aphthous stomatitis, Pharyngitis,
Adenitis (PFAPA) Syndrome. Broderick L, Page N, Carvalho D, Magit
A, Jiang W, Simon L, Bothwell M,
Kearns D, Pransky S, Hoffman H. The
Federation of Clinical Immunology
Societies, Boston, MA, June 2010
Pediatric caudal septal deviation and the
Guillen suture technique: Does it provide
better results? Pellman L, Carvalho D.
Society of Ear, Nose and Throat Advances
in Children 38th Annual Meeting, Cincinnati, OH, December 2010
Radiation exposure in pediatric cystic
fibrosis patients with Chronic Sinonasal Disease: A 10-year review. Topp
S, Donaldson C, Jiang W, Carvalho D.
American Society of Pediatric Otolaryngology 26th Annual Meeting,
Chicago, CA, May 2011
Hearing Loss in Newborns and Infants,
Pediatric Update, Vol. 32, Moderator:
Seth Pransky; Discussants: Daniela Carvalho and Natalie Loundon,
March 1, 2012
Genetics Of PFAPA Syndrome, Broderick L, Carvalho D, Magit A, Jiang W,
Leuin S, Bothwell M, Kearns D, Pransky S, Hoffman HM. 7th Congress of
ISSAID (International Society of Systemic Auto-Inflammatory Diseases),
Geneva, Switzerland, May 2013
Poster Presentations
Cerebral magnetic resonance imaging
and white matter changes in pediatric cochlear implant recipient. Society
Children 37th Annual Meeting, Salt
Lake City, UT, December 2009
Bilateral severe inner ear abnormalities
in profoundly deaf non-twin siblings.
Society for Ear, Nose and Throat
Advances in Children 37th Annual
Meeting, Salt Lake City, UT, December 2009
Distal renal tubular acidosis and sensorineural hearing loss: A case report.
Meeting, Salt Lake City, UT, December 2009
Individualized treatment of lateral sinus
thrombosis-Is mastoidectomy necessary? American Society of Pediatric
Otolaryngology 25th Annual Meeting, Las Vegas, NV, May 2010
High-riding jugular bulb resulting in
conductive hearing loss. Society for
Ear, Nose and Throat Advances in
Children 38th Annual Meeting, Cincinnati, OH, December, 2010
Invited Lectures
International:
Sinusitis en niños: Cirugia endoscopica ¿Si o no? (Sinusitis in Children:
Endoscopic surgery, yes or no?). XVI
Congreso Estatal de Pediatria, XIX
55
1/23/14 4:46 PM
Jornadas Pediatricas del Colegio de
Pediatras Capitulo Ensenada y Primer
Encuentro Internacional de Pediatria,
Ensenada, Mexico, June 27 2009
Atualização em otorinopediatria (Update
on pediatric otolaryngology). International Grand Rounds of the
Otolaryngology, Head and Neck Surgery department, UNICAMP (State
University of Campinas), Campinas,
Brazil, July 2, 2010
International Guest Faculty of the 40th
Brazilian Congress of Otorhinolaryngology and Cervico-Facial Surgery,
Natal, Brazil, November 23, 2010
- Síndrome de Down e otorrinolaringologia (Down Syndrome and
otolaryngology)
- Síndromes genéticas em otorrinolaringologia (Genetic syndromes in
otolaryngology)
- Otologia pediátrica (Pediatric otology)
- Avanços em estridor na infância(Ad
vances in stridor)
International Guest Faculty of the I
Pediatric Otolaryngology Meeting/
IV Pediatric Airway Meeting of the
HCPA, Porto Alegre, RS, Brazil, June
24-26, 2011
- Ruído respiratório: Diagnóstico
diferencial (Differential diagnosis in
upper respiratory sounds)
- Hemangiomas em via aérea (Airway
hemangiomas)
- Painel: Tratamento da surdez neurosensorial (Panel: Treatment of
sensorineural), Síndromes genéticas
em otorrinolaringologia” (Genetic
syndromes in otolaryngology
- Avanços em massas cervicais na
infância (Advances in pediatric neck
masses)
Imaging and Genetics in Auditory Neuropathy Spectrum Disorder: Is it just
a wiring problem? San Diego Sound
Wave Symposium, San Diego, CA,
October 13, 2012
Update on Pediatric Hearing Loss,
Practical Pediatrics, Escondido, CA,
October 27, 2012
Lots of Snot and Cough: Is it a Sinus
Infection? 15th Annual School Health
Leadership Conference (AAP Chapter
3 CA), San Diego, CA, November 3,
2012
56
Management & Evaluation of a Child
with Recurrent Croup, 2012 Ultimate
Colorado Mid-Winter Meeting, Vail,
CO, February 6, 2013
Hearing Loss in Children, Early Start Parent group meeting, Lafayette School,
San Diego, CA, February 27, 2013
Television, Radio, Newspaper and Web
Rady’s Celebrates Kids with Cochlear
Implants, interview by Katie Orr,
KPBS, June 15, 2009
Music for Her Ears, Kids News Day San
Diego Union Tribune, October 20, 2009
Entrevista Dra. Carvalho, Ipod afecta
jovenes (Interview with Dr. Carvalho:
Ipod affects teenagers). Interview in
Spanish for the TV channel Univision,
August 23, 2010
Teens and hearing loss. Interview for Channel 6 San Diego, September 2, 2010
Aumentan casos de sordera en jóvenes
(Increase in the number of teenagers
with hearing loss). Diário San Diego,
September 9, 2010
“A criança ruidosa”(The noisy child),
lecture given online for the Brazilian
Academy of Otolaryngology (ABORLCCP) “Otoweb”, with live transmission
to all Brazil, May 29, 2012
“Surge nueva condición médica conocida
como ‘sordera del iPod’” (A new medical condition arises known as “iPod
deafness”), interview for the program
Primer Impacto, Channel Univision,
September 5, 2012
“Rady Children’s Hospital Joy of Sound,”
interview for the program Good
Morning San Diego, TV Channel
KUSI, June 20, 2013
Wen Jiang, MD
•
•
•
•
ITCommittee–Member
DivisionofPediatricOtolaryngology
DirectorofThyroidDiseaseCenter
Director of Speech Endoscopy
Program
• DirectorofIT
• DirectorofInvitedLectureSeries
Is mastoidectomy necessary? Pellman
L, Simon L, Jiang W, Carvalho D.
Individualized treatment of lateral
sinus thrombosis. American Society of Pediatric Otolaryngology 25th
Annual Meeting, Las Vegas, NV, May
2010
Radiation exposure in pediatric cystic
fibrosis patients with chronic sinonasal disease: a 10 year review. Topp SG,
Donaldson C, Jiang W, Carvalho D.
American Society of Pediatric Otolaryngology Annual meeting, Chicago,
April 30, 2011
Temporary Tracheotomy for Removal of
a Large Airway Foreign Body– When
Bronchoscopy is not Enough. Nadaraja
GS, Jiang W, Carvalho D. American
Broncho-Esophagological Association’s
93rd Annual Meeting, Orlando, FL,
April 10-11, 2013
Best Doctors in America 2009, 2010, 2011
San Diego Super Doctors, 2011
Super Doctors 2012, 2013
Founder’s Award Fresh Start Surgical
Gifts, San Diego, CA 2011
U.S. News & World Report Top Doctor
2012-2013
Castle Connolly Top Doctors 2012-2013
• ChiefChiefMedicalOfficer
• BoardofTrustees(ex-officio)
Senior Vice president Health Affairs
• Supply and Equipment Task Force,
co-chairman
• Co-Chairman, RCHSD Supply and
Equipment Task Force 2011-current
• SurgeoninChief
Other Institutions
• National Association of Children’s
Hospitals and Related Institutions
• Hospital De Las Californias Binational Committee
• Organization of Children’s Hospitals
Surgeons in Chiefs
• MakeaWish,MedicalAdvisoryBoard
University Committees
University of California San Diego:
Joint Risk Management Committee,
Chairman
1/23/14 4:46 PM
Department of Surgery Credentials ad
hoc Committee, Chairman
Academic Advisory Committee
Neonatology Search Committee, Chairman
Skaggs School of Pharmacy Dean Search
Committee
Neonatology Chief Search Committee
Pediatric Hepatology Search Committee
Quality and Innovation Chief Search
Committee
Cardiac Surgery Search Committee
Transplant Cardiology Search Committee
Pediatric GI Chief Search Committee
Surgeon in Chief Search Committee
Department Of Surgery Chairman Search
Committee
Presentations
Cellular immunity in periodic fever,
aphthous stomatitis, pharyngitis, adenitis (PFAPA) syndrome. Broderick L,
Page N, Carvalho D, Magit A, JiangW,
Simon L, Bothwell M, Kearns D, Pransky S, Hoffman H. The Federation of
Clinical Immunology Societies, Boston, MA, June 2010
Medical Practice Foundation Update.
UCSD Department of Surgery, La
Jolla, CA, 2010
The Medical Practice Foundation: A
new model for pediatric healthcare.
Leadership Development Institute,
RCHSD, San Diego, CA, 2010
Work environment and condition associated discomfort and injury. Cavanagh
J, Hong P, Kearns D. Annual Resident
Research Day, Dalhousie University,
Halifax, Nova Scotia, Canada, April
2011
An ergonomics survey study of the
American Society of Pediatric Otolaryngology Members. Cavanagh J,
Hong P, Kearns D. Canadian Society
of Otolaryngology, Victoria, British
Columbia, Canada, May 2011
Work environment and condition associated discomfort and injury. Cavanagh J,
Hong P, Kearns D. American Society of
Pediatric Otolaryngology 26th Annual
Meeting, Chicago, IL, May 2011
Discovery at RCHSD. Leadership Development Institute, RCHSD. San Diego,
CA, 2011
Pediatric disaster surge training. San
Diego County Healthcare Disaster
Council, San Diego, CA, 2011
Business Domain Curriculum. UCSD
Pediatric Hospital Medicine Fellowship Course, UCSD Department of
Pediatrics, San Diego, CA, 2011
Immunoregulation at the Cellular Level
in Periodic Fever, Aphthous Stomatitis, Pharyngitis Adenitis (PFAPA)
Syndrome. Broderick L, Carvalho D,
Magit A, Jiang W, Bothwell M, Kearns
D, Pransky S, Hoffman H. Pediatric
Translational Research Symposium,
Rady Children’s Hospital, San Diego,
CA, October, 2011
Periodic Fever, Aphthous Stomatitis, Pharyngitis, Adenitis (PFAPA)
Syndrome: Evaluation of Patients.
Broderick L, Magit A, Hoffman H,
Carvalho D, Kearns D, Pransky S,
Bothwell M, Jiang W. American
Academy of Allergy, Asthma and
Immunology, Orlando, FL, March,
2012
Evaluation of San Diego County Disaster
Preparedness Best Practices. Hilfiker
M, Abe C, Cox S, McDonough L,
Rodriguez J, Kearns D. Trauma Center
Association of America, Charleston,
S.C., October 2012
Physician/Hospital Alignment in Pediatrics, Panelist for Webinar in
Conjunction with ECG Management
Consultants, 2012
Pediatric Airway Obstruction, Scripps
Mercy Pediatric Grand Rounds, San
Diego, CA, 2012
Stridor in Children, Scripps Mercy Pediatric Grand Rounds, San Diego, CA,
2012
Medical Practice Foundation Update.
Leadership Development Institute.
Rady Children’s Hospital and Health
Center. San Diego, CA, 2012
Physician Hospital Relationships in Pediatrics. Children’s Hospital Association
National Conference, Garden Grove,
CA, March, 2013
Shelby Leuin, MD
National Society Activities
10/2012-9/14 Member, Pediatric Otolaryngology Education Committee
Posters Presentations
Pediatric Salivary Gland Tumors. Lago D,
Leuin SC, Pransky S. Poster presenta-
tion at the Society of Ear, Nose, and
Throat Advances in Children Annual
Meeting Charleston, SC on November
30-December 2, 2012
Anosmia in the Pediatric Population. Lago
D, Leuin SC, Pransky S. Poster presentation at the American Society of Pediatric
Otolaryngology Annual Meeting San
Diego, CA, April 20-22, 2012
Hoarseness as a Presenting Sign of Kawasaki Disease. Shanbhag S, Burns JC,
Tremoulet AH, Sato YZ, Lago D,
Leuin SC. Poster presentation at the
10th International Kawasaki Disease
Symposium in Kyoto, Japan, February
7-10, 2012
Functional Rhinoplasty and Percutaneous
Otoplasty. Poster presentation at the
2012 Annual Physician Meeting, Children’s Physicians Medical Group, San
Diego, CA, May 10, 2012
Invited Lectures
Pediatric Neck Masses. Presented at the
Advances in the Practice of Pediatrics 27th Annual CME Conference in
San Diego, CA, March 24, 2013
Pediatric Neck Masses. Presented at the
Invited Speaker Conference at Rady
Children’s Hospital, September 21,
2012
Pediatric Neck Masses: The good, the bad,
and the ugly. Invited Lecture Pediatric
Grand Rounds, Rady Children’s Hospital, August 24, 2012
Cleft Palate: An Otolaryngology Perspective. Presented at the Cleft Palate Care:
A Team Approach Conference, San
Diego, CA, March 3, 2012
Anthony Magit, MD
• Best Doctors in America 2009, 2010,
2011, 2012, 2013
• Received MPH from Johns Hopkins
Bloomberg School of Public Health
May, 2012. Master’s thesis: Basilar Skull
Fractures in Infants and Children
• President, Society of Ear, Nose and
Throat Advances in Children
• Co-Chairman, American Society of
Pediatric Otolaryngology Ad Hoc
Education Committee (2010)
57
1/23/14 4:46 PM
• American Society of Pediatric Otolaryngology: Member Vascular
Malformations Task Force
• AmericanAcademyofOtolaryngology-Head and Neck Surgery: Member
Guideline Panel
• American Academy of Otolaryngology-Head and Neck Surgery, Member
Clinical Guideline Development Project
• ImmediatepastChiefofStaff
• MedicalStaffExecutiveBoard
• Chairman, Credentials Committee
(2010)
• Chairman,InstitutionalReviewBoard
• Co-Chairperson Quality, Safety and
Medical Affairs Committee
• Chairman,BylawsCommittee
• Member,BoardofGovernorsMedical
Practice Foundation
• Member,VascularLesionsClinic
• Member, Clinical Research Advisory
Committee
• Vice-Chairman,AcademicAffairsand
Research Committee
University California San Diego
• Member, UCSD Department of Surgery Research Advisory Committee
• Member, UCSD Pediatric Human
Subjects Protection Program
• Co-director, UCSD medical school
medical student mentor program
• Member, UCSD pediatric Human
Subjects Protection Program (IRB)
committee
• Mentor,UCSDHealthMentorsProgram
San Diego County/Regional Service
• Elected San Diego County Medical
Society Board of Directors
• Volunteer, San Diego City Schools
Hearing Program
• Volunteer,FreshStartSurgicalGifts
State of California Service
• Member, Board of Directors Children’s Specialty Care Coalition
Scientific Presentations
Chronic sinusitis in children. Instruc58
tional Course, American Academy of
Otolaryngology-Head & Neck Surgery Annual Meeting, 2009, 2010,
2011, 2012
Stridor in infants and children. Instructional Course, American Academy of
Otolaryngology-Head&NeckSurgery
Annual Meeting, 2009, 2010, 2011
Invited lecture, Cystic Fibrosis Update.
UC Davis Otolaryngology-Head &
Neck Surgery Grand Rounds, Sacramento, CA, January 25, 2011
Treatment of large lymphatic malformations of the head and neck in patients
in early infancy. Society of Ear, Nose
and Throat Advances in Children 37th
Annual Meeting. Salt Lake City, UT,
December 2009
Aspiration for management of large head
and neck lymphatic malformations
in early infancy. Society of Ear, Nose
Annual meeting. Salt Lake City, UT,
December 2009
Invited lectures
Panel Member, Management of Lymphatic
Malformations American Society of
Meeting. April 26, 2013 Alexandria, VA
Seth Pransky, MD
Best Doctors in America 2009, 2010,
2011, 2012, 2013
Best Doctors San Diego 2009, 2011, 2012,
2013
Castle Connolly Top Doctors 2012-2013
Ray Skoglund Excellence in Teaching
Award RCHSD 2011
Chevalier Jackson Award, for Outstanding Achievement and accomplishment
in Bronchoesophagology, from The
American Broncho-Esophagological
Association 2013
• Society of Ear, Nose and Throat
Advances in Children, Member Program Committee for National Annual
Meeting 2011
• Recurrent Respiratory Papillomatosis
Task Force, Member, American Society Pediatric Otolaryngology
• Director,SatelliteServices
• RCHSDCMEDirectorPracticalPediatrics 2001-present
• Member,MarketingCommittee
• Member, Regional Task Force
Committee
• Member, Children Health Network
Marketing Committee
• Surgeon in Chief, Search Committee
2013• Network Governance Committee
2013• ServiceLineDevelopmentCommittee
2013Rady Children’s Specialists of San
• Director, Pediatric Otolaryngology
Department
• Member,ExecutiveBoardofDirectors
• Director,ClinicalPracticeCommittee
• Director,
Clinical
Operations
Committee
• ViceChair,MarketingCommittee
• PulmonaryDivisionPhysicianSearch
committee 2012• SpacePlanningCommittee2013Scientific Presentations
Simon LM, Tylor DA, Jiang W, Carvalho D,
Bothwell MR, Kearns DB, Pransky SM,
Magit AE. Survey of thyroglossal duct
cyst in a subspecialty referral practice.
24th Annual American Society of Pediatric Otolaryngology Annual Meeting,
Seattle, WA, May 2009
Intralesional cidofovir for the treatment of
pediatric recurrent respiratory papillomatosis. American Society of Pediatric
Otolaryngology. 24th Annual Meeting,
Seattle, WA, May 22, 2009
Trying to understand PFAPA and its
management: Preliminary results of
a prospective clinicopathologic study.
Meeting, Salt Lake City, UT December
6, 2009
Inferior Turbinate reduction using coblation in a pediatric population:
A prospective clinical evaluation.
American Society of Pediatric Otolaryngology 25th Annual Meeting, Las
Vegas, NV, May 1, 2010
1/23/14 4:46 PM
Prevalence of elevated IGE levels in a
consecutive series of pediatric ENT
patients. Society for Ear, Nose and
Throat Advances in Children 38th
Annual Meeting. Cincinnati, OH,
Dec. 2, 2010
Pediatric inferior turbinate reduction: Comparison of coblation and
radiofrequency ablation techniques.
American Society of Pediatric Otolaryngology 24th Annual Meeting,
Seattle, WA, May 22, 2009
Button battery ingestion in the pediatric
population. American Academy of
Otolaryngology Annual Meeting, San
Diego, CA, October 4-7, 2009
Management of ankyloglossia in infants
with compromised feeding. Society
Children 37th Annual Meeting, Salt
Lake City, UT, December 3-6, 2009
Vocal cord paralysis in infants with tracheoesophageal fistulas. Society for
Ear, Nose and Throat Advances in
Children 38th Annual Meeting, Cincinnati, OH December 2, 2010
American Society of Pediatric Otolaryngology 27th Annual Meeting.
Scientific Poster: Anosmia in the Pediatric Population, San Diego, CA, April
19-22, 2012
Invited Lectures
International
Visiting Professor, LIX Annual Mexican
Congress of Otolaryngology. Veracruz, Mexico, July 22-25, 2009
- Rhinosinusitis in Children: Diagnosis and Management
- The Draining Ear in Children
- Round table: Management of Surgical Complications in Pediatric
Otolaryngology
- Human Papilloma Virus: Present
and Future
- Stridor in Infancy: Diagnosis and
Management
Invited Lecture, Human papilloma virus,
present and future management
issues. University of Montreal, Montreal, Canada, August 3, 2009
Invited Lecture, Otorrhea in children:
Approach and management 2009.
3rd Annual McGill Auditory Sciences
Laboratory Guest Lectureship, Montreal Children’s Hospital, Montreal,
Canada, August 4, 2009
Invited Professor, X European Society of
Pediatric Otolaryngology. Pamplona,
Spain, June 5-8, 2010 Round table:
Voice Disorders: Papillomatosis
Invited Guest Professor, Department
of Otolaryngology University Medical Center, Utrecht. Grand Rounds:
Update of Otorrhea 2011. Utrecht,
The Netherlands, March 15, 2011
Invited Lecture, Management of sinusitis in young children. Dialogues
in Pediatric Otorhinolaryngology.
Champery, Switzerland, June 26–29,
2011
Panel Instructor/Moderator, European
Society of Pediatric Otolaryngology
11th International Congress. Handling the Patient Load in Different
Societies. Amsterdam, Netherlands,
May 20-23, 2012
Panel Chairman, European Society of Pediatric Otolaryngology 11th International
Congress. Effective Teaching in Pediatric Otorhinolaryngology. Amsterdam,
Netherlands, May 20-23, 2012
Guest Professor, LXIX Chilean Congress
of Otorhinolaryngology, Concepcion, Chile November 7-10, 2012.
Presentations:
1) Chronic Sinusitis in Children: Role
of the Turbinates
2) Management of Nasal Obstruction
of the Newborn
3) Update in Otitis Media 2012
4) Update in the Treatment of Subglottic Hemangiomas 2012
5) Alternatives in Management of Airway Endoscopy
6) State of the Art Treatment of Recurrent Respiratory Papillomatosis 2012
7) Round table: Glottic and Subglottic
Stenosis in Children
Guest Professor, Controversies in Pediatric Otolaryngology. Department of
Otolaryngology Tel Aviv Sourasky
Medical Center, Dana Children’s Hospital. January 18, 2013
1) Aerodigestive Tract Foreign Bodies:
The New and the Old
2) Panel Moderator-presentation: The
Legacy of Tympanostomy Tubes
3) Pediatric Airway Panel; Case
Management
Faculty, Invited Panel Lecturer, International
Federation of Oto-Rhino-Laryngological Societies World Congress. Panel:
Decision Making in the Treatment of
Subglottic Stenosis in Children: Sharing
the Airway with Anesthesia: Techniques
for Subglottic Airway Abnormalities
Seoul, Korea, June 3, 2013
National Director, International Endoscopy Days, San Diego, CA, 2009, 2012
Chronic sinusitis in children. Instructional Course American Academy of
Otolaryngology-Head & Neck Surgery Annual Meeting, 2009, 2010,
2011, 2012
Stridor in infants and children. Instructional Course American Academy of
Otolaryngology-Head&NeckSurgery
Annual Meeting, 2009, 2010, 2011
Panel Moderator, Socioeconomic Panel:
How to enhance your practice with
clinical support. American Society of
Meeting. Seattle, WA, May 22, 2009
Faculty, 34th National Primary Care
Nurse Practitioner Symposium Copper Mountain, CO, July 16-19, 2009
Foreign Bodies of the Ear, Nose and
Throat.
Faculty, Ultimate Colorado Mid-Winter
Meeting: An Otolaryngology Update.
Finesse in pediatric bronchoesophagology for the general otolaryngologist.
Vail, CO, Jan 24-28, 2010
Faculty, Western Section of Pediatric Otolaryngology (WESPO) Annual Meeting.
Alternatives in endoscopic airway management. UCLA Medical Center Los
Angeles, CA, March 13, 2010
Panel Member American Academy of
Otolaryngology Annual Scientific
Meeting Pediatric Otolaryngology
Miniseminar: Adjuvant Therapy for
Juvenile Recurrent Respiratory Papillomatosis. Boston, MA, Sept 26-29, 2010
Faculty, 67th Annual Brennemann
Memorial Lectures; Los Angeles Pediatric Society, Anaheim, CA, October
7-10, 2010
- The Green Runny Nose-Is It Really
Sinusitis
- Hearing Loss in Infants and
Newborns
59
1/23/14 4:46 PM
- Neck Masses-Differentiating Horses
From Zebras
- Round Table sessions: Stridor:
Assessing the Airway from the Nose
to the Lung
Faculty, Pediatric Potpourri State of the
Art 2011. AAP, California District
IX, Chapter 2, Children’s Hospital Los
Angeles Meeting, Maui, HI, February
12-18, 2011
- Neck Masses-Horses and Zebras
- The Runny Nose-Chronic Sinusitis
and Beyond
- Foreign Bodies of the Aerodigestive Tract- What Must I Discuss with
Parents
- Update on Otorrhea-2011
- Update on Otitis media-2011
- Stridor: From the nose to the lung
(Lunchtime Seminar, repeated three
times)
Panel Moderator, Pediatric Airway Nightmares. American Society of Pediatric
Otolaryngology 26th Annual Meeting, Chicago. IL, April 29, 2011
Invited Lecture, Practical Pediatrics CME.
Foreign Bodies of the Aerodigestive
Tract-What Must I Discuss with Parents. San Diego, CA, May 14, 2011
Faculty, Massachusetts Eye and Ear Institute Update in Pediatric Airway, Voice
and Swallowing Disorders. Recurrent
Respiratory Papillomatosis and the
Voice: Treating the Airway and the
Voice. Boston, MA, May 21, 2011
Invited Lecture, Current State of Recurrent Respiratory Papillomatosis.
Festschrift Honoring Robin Cotton,
M.D. Boston, MA November 5, 2011
Panel Moderator, Society for Ear, Nose
Annual Meeting. The Legacy of the
Cleft Palate Ear: Management Dilemmas. Kansas CityMO, Dec 1-4, 2011
Faculty, AAP Chapter 3 Advances in
the Practice of Pediatrics. Presentation: Ankyloglossia and Nursing. San
Diego, CA, March 23-25, 2012
Guest Professor, Fifth Annual New York
City Airway Symposium. New York,
NY October 11th, 2012. Presentations:
1) Medical and Surgical Approaches to
the Young Child with Chronic Sinusitis
2) The Legacy of Tympanostomy
Tubes-Sometimes It’s Not Just a Tube
60
Instructor, Pediatric Otolaryngology Fellow’s Webinar: Management of the
Acute Airway. October 2012
Guest Professor, Billings Clinic Grand
Rounds. Billings, Montana. February
22nd, 2013. Pediatric Neck Masses
Guest Professor, Montana Society of Otolaryngology-Head and Neck Surgery
Annual Meeting. Big Sky, Montana.
Feb 23-24, 2013
1) Pediatric Stridor and Airway
Management
2) Chronic Sinusitis in Children
3) Update of recurrent respiratory
Papillomatosis 2013
4) Update on Otitis Media and Thoughts
on Tympanostomy Tubes 2013
Panel Moderator, Robin Cotton Panel: My
Worst Errors-Cases I Wish I Could Do
Again American Society of Pediatric
Otolaryngology 28th Annual Meeting.
April 26, 2013 Alexandria, VA
Guest Professor, New York University
ENT Grand Rounds. Esophageal Foreign Bodies: The Old and the New.
New York, NY, August 14, 2013
PUBLICATIONS
Blakely E, Magit A. The role of tonsillectomy in reducing recurrent
pharyngitis: A systematic review. Otolaryngology-Head and Neck Surgery,
140:291-297, 2009.
Bothwell M. Twisted Trick. Science World,
October 2009.
Kearns D, Woods M, Summerside P.
Redefining the physician executive.
Physician Executive, 35(1):32-38, 2009.
Neely G, Magit E, et al. A practical guide to
understanding systematic reviews and
meta-analyses. Otolaryngology-Head
and Neck Surgery, 140:291-297, 2009.
Smith M, Zimmerman M, Burke D,
Magit A. et al. Efficacy and safety
of OK-432 immunotherapy of lymphatic malformations. Laryngoscope,
119(1):107-15, 2009.
Bothwell M. P3 Generation: Noise-induced hearing loss rising among
children and adolescents. ENT Today,
January 2010.
Nely J, Magit A, Rich J, Voelker C, Wang
E, Paniello R, Nussenbaum B, Bradley
J. A practical guide to understanding
systematic reviews and meta-analyses.
Otolaryngol Head Neck Surg, 142(1):614, 2010.
Hong P, Jurkowski Z, Carvalho D. Preoperative cerebral magnetic resonance
imaging and white matter changes
in pediatric cochlear implant recipients. Int J Pediatr Otorhinolaryngol,
74(6):658-60, 2010.
Greenberg M, Carvalho D. Endoscopic
adenoidectomy secondary to drug
induced trismus. Scientific Research,
1(1):27-29, 2010.
Hong P, Lago D, Seargeant J, Pellman L,
Magit A, Pransky S. Defining ankyloglossia: A case series of anterior and
posterior tongue ties. Int J Pediatr Otorhinolaryngol, 74(9):1003-1006, 2010.
Wu A, Carvalho D. Congenital tympanic
ring defect presenting as an external
auditory canal mass. Ear, Nose and
Throat Journal, 89(10):E44, 2010.
Hilfiker M, Hulson J, Kearns D. Ergonomics and the physician executive.
Physician Executive, 36(3):54-7, 2010.
Page N, Kearns D. Labyrinthitis ossificans.
Arch of Oto HNS, 137(3):303-305, 2011.
Cole S, Kearns D, Magit A. Chronic
esophageal foreign bodies and secondary mediastinitis in children.
Annals of Otology, Rhinology & Laryngology Ann Otol Rhinol Laryngol.
120(8):542-5, 2011.
Leuin SC, Shanbhag S, Lago D, Sato Y,
Sun X, Jain S, Burns JC, Tremoulet
AH. Hoarseness as a Presenting Sign
in Children with Kawasaki Disease.
Pediatr Infect Dis J, 2013 Jul 9. [Epub
ahead of print] PMID 23811742.
Leuin SC, Deschler D. The Missing
Tracheo-Esophageal Puncture Prosthesis: Evaluation and Management.
Ear Nose Throat J, 92(2): E14-16, 2013.
Leuin SC, Chan KH, Upper Lip Dermoid
in a 13-Month-Old Child. Otolaryngol
Head Neck Surg, 147(2): 392, 2012.
Cavanagh J, Brake M, Kearns D, Hong
P. Work environment discomfort and
injury: An ergonomic survey study
of the American Society of Pediatric
Otolaryngology members. Am J Otolaryngol, 33(4):441-6, 2012 Epub Dec
7, 2011.
Broderick L, Carvalho D, Magit A, Jiang
W, Bothwell M, Kearns D, Pransky S,
Hoffman H. Periodic Fever, Aphthous
1/23/14 4:46 PM
Stomatitis, Pharyngitis, Adenitis
(PFAPA) Syndreome: Evaluation of
Patients in San Diego, CA. Journal
of Allergy and Clinical Immunology,
129(2) Supplement AB214, 2012.
Hong P, Bezuhly M, Taylor MS, Hart RD,
Kearns DB, Corsten G. Tracheostomy
versus Mandibular Distraction Osteogenesis in Canadian children with
Pierre Robin Sequence: A Comparative Cost Analysis. J Otolaryngol Head
Neck Surg, 1;41(3):207-14,2012.
Hong P, Graham E, Belyea J, Taylor SM,
Kearns DB. The Long-Term Effects
of Mandibular Osteogenesis on
Developing Deciduous Molar Teeth.
Plastic Surgery International, Vol.
2012, Article ID 913807, 5 pages,
2012. doi:10.1155/2012/913807.
Broderick L, Carvalho D, Magit A, Jiang
W, Leuin S, Bothwell M, Kearns D,
Pransky S, Hoffman H. Genetics of
Periodic Fever, Aphthous Stomatitis, Pharyngitis, Adenitis (PFAPA)
Syndrome. Journal of Allergy and Clinical Immunology, 131(2) Supplement
AB159, 2013.
Macdonald KI, Gipsman A, Magit A,
Fandino M, Massoud E, Witterick
IJ, Hong P. Endoscopic sinus surgery
in patients with cystic fibrosis: a systematic review and meta-analysis of
pulmonary function. Rhinology, 50(4).
360-9, 2012.
Ambrosio A, Magit A. Respiratory distress of the newborn: congenital
laryngeal atresia. Int J Pedatr Otorhinologol, 76(11): 1685-7, 2012.
Hong P, McNeil M, Kearns DB, Magit
AE. Mandibular distraction osteogenesis in children with Pierre Robin
sequence: impact on health related
quality of life. Int J Pedatir Otorhinolaryngol, 76(8):1159-63, 2012.
Simon LM, Magit AE. Impact of incision
and drainage of infected thyroglossal
duct cyst on recurrence after Sistrunk
procedure. Arch Otolaryngol Head
Neck Surg, 138(1):20-4, 2012.
Hong P, Brake MK, Cavanaugh JP,
Bezuhly M, Magit AE. Feeding and
mandibular distraction osteogenesis in children with Pierre Robin
sequence: A case series of functional
outcomes. Int J Pediatr Otorhinolaryn-
gol, 76(3):414-8, 2012.
Park E, Pransky S, Malicki D, Hong P.
Unilateral Lymphangiomatous Polyp
of the Palatine Tonsil in a Very Young
Child: A Clinicopathologic Case
Report. Case Reports in Pediatrics, Vol.
2011, Article ID 451542, 3 pages, 2011.
Derkay C, Volsky P, Rosen C, Pransky S,
McMurray JS, Chadha N, Froehlich P.
Current Use of Intralesional Cidofovir
of Recurrent Respiratory Papillomatosis. Laryngoscope, 000: 1-8. 2012.
Jones TA, Jones S, Vijayakumar, S, Bothwell M. The adequate stimulus for
mammalian linear vestibular evoked
potentials (VsEPs). Jones TA, Jones
SM, Vijayakumar S, Brugeaud A,
Bothwell M, Chabbert C. Hear Res,
280(1-2):133-40, 2011.
Books and Book Chapters
Abe C, McDonough L, Cox S, Phalen
D, Parker M, Hilfiker M, Schnell K,
Kearns D. Pediatric Surge Planning.
Train the Trainer. San Diego County
Healthcare Disaster Council, San
Diego, CA, 2011.
Pransky S, Simon L. Clinical Evaluation
of Stridor. Handbook of Pediatric
Otolaryngology, Shapiro, NL Editor,
World Scientific Publishing Co., Singapore, pp. 183-212. 2011.
Magit A. Acute Upper Airway Obstruction.
Textbook of Clinical Pediatrics. Second
Edition, Elzouki, A Editor, Springer-Verlag, Berlin Heidelberg, 2012.
Magit A. Congenital Anomalies of the
Respiratory Tract. Textbook of Clinical
Pediatrics, Second Edition, Elzouki, A
Editor, Springer-Verlag, Berlin Heidelberg, 2012.
Magit A. History and Physical Examination.
Textbook
of
Clinical
Pediatrics.Second Edition, Elzouki, A
Editor, Springer-Verlag, Berlin Heidelberg, 2012.
Pransky S, Tylor D. Neoplasms of the Larynx, Trachea and Bronchi. Pediatric
Otolaryngology, Bluestone CD, Stool
SE, Editors, Fifth Edition, BC Decker,
Inc. Toronto, Canada (in press).
Peterson MB, Pransky SM. Managing
Recurrent Respiratory Papillomatosis
and Care of the Voice. Pediatric Voice
Disorders. Hartnick, CJ, Boseley, ME
Editors, Pleural Publishing Inc., San
Diego, CA. pp 191-204, 2012.
Pransky SM, Francis CL. Stridor in
Infants and Children. Pediatric Otolaryngology. Schoem, SR, Darrow,
DH Editors, American Academy of
Pediatrics, Chicago, Il. Chapter 15, pp
323-352, 2012.
Leuin SC. Chronic Sinusitis. Chapter,
Pediatric Otolaryngology Education
Committee, American Academy of
Otolaryngology
Publications in Press
Alyono J, Hong P, Nathan C, Bothwell M.
Second branchial cleft anomaly with
an ectopic tooth: A case report. ENT
Journal.
Mani N, McLeod, Jasmine, Sauder DN,
Mani N, Haft M, Bothwell M. Novel
use
of
Polymethylmethacrylate
(PMMA) microspheres in the treatment of infraorbital rhytids. Journal of
Cosmetic Dermatology, 32(8):749-59.
Dutton P, Edmonds EW, Lark
RK, Mubarak SJ: Prevalence of
painful peroneal tubercles in the pediatric population. J Foot Ankle Surg,
51(5):599-603, 2012.
Wenger DR, Hosalkar HS. Principles
of treating the sequelae of Perthes
disease. Orthop Clin North Am,
42(3):365-72, vii, 2011.
Podeszwa DA, Mubarak SJ. Physeal
fractures of the distal tibia and fibula
(Salter-Harris Type I, II, III, and IV
fractures). J Pediatr Orthop, 32 Suppl
1:S62-8, 2012.
Edmonds EW, Roocroft JH, Mubarak SJ.
Treatment of displaced pediatric supracondylar humerus fracture patterns
requiring medial fixation: a reliable and
safer cross-pinning technique. J Pediatr
Orthop, 32(4):346-51, 2012.
Gantsoudes GD, Roocroft JH, Mubarak SJ.
Treatment of talocalcaneal coalitions. J
Pediatr Orthop. 32(3):301-7, 2012.
Chang RF, Mubarak SJ. Pathomechanics
of Gowers’ sign: A video analysis of a
spectrum of Gowers’ maneuvers. Clin
Orthop Relat Res, 470(7):1987-91, 2012.
Wenger DR. Limitations of evidence-based
medicine: the role of experience and
expert opinion.J Pediatr Orthop, 2012
Sep;32 Suppl 2:S187-92.
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Smith LR, Chambers HG, Subramaniam S, Lieber RL. Transcriptional
abnormalities of hamstring muscle
contractures in children with cerebral
palsy. PLoS One, 2012;7(8):e40686.
doi: 10.1371/journal.pone.0040686.
Epub 2012 Aug 16.
Chambers HG, Shea KG, Anderson AF,
Jojo Brunelle TJ, Carey JL, Ganley
TJ, Paterno M, Weiss JM, Sanders
JO, Watters WC 3rd, Goldberg MJ,
Keith MW, Turkelson CM, Wies JL,
Raymond L, Boyer KM, Hitchcock K,
Sluka P, Boone C, Patel N, American
Academy of Orthopaedic Surgeons:
American Academy of Orthopaedic
Surgeons clinical practice guideline
on: The diagnosis and treatment of
osteochondritis dissecans. J Bone Joint
Surg Am, 94(14):1322-4, 2012.
Tis JE, Edmonds EW, Bastrom T, Chambers HG. Short-term results of
arthroscopic treatment of osteochondritis dissecans in skeletally immature
patients. J Pediatr Orthop. 32(3):22631, 2012.
Chambers HG, Becker RE, Hoffman
MT, Hartley-McAndrew M, Stein MT
.Managing Behavior for a Child with
Autism in a Body Cast. J Dev Behav
Pediatr, 33:506-508, 2012.
Reduced Satellite Cell Population May
Lead to Contractures in Children with
Cerebral Palsy. Dev Med Child Neurology, 2012.
Synovial chondromatosis in a child’s
literature. Hand (NY), 7(1):98-102, 2012.
Pring ME. Pediatric radial neck fractures:
when and how to fix.J Pediatr Orthop,
32 Suppl 1:S14-21. 2012.
Koenig JK, Pring ME, Dwek JR. MR
evaluation of femoral neck version
and tibial torsion. Pediatr Radiol,
42(1):113-5, 2012.
Robertson NB, Roocroft JH, Edmonds
EW. Childhood metatarsal shaft fractures: treatment outcomes and relative
indications for surgical intervention. J
Child Orthop, 6(2):125-9, 2012.
Pandya NK, Edmonds EW. Immediate
intramedullary flexible nailing of open
pediatric tibial shaft fractures. J Pediatr
62
Orthop, 32(8):770-6, 2012.
Bailey JR, Eisner EA, Edmonds EW.
Unwitnessed magnet ingestion in a
5 year-old boy leading to bowel perforation after magnetic resonance
imaging: case report of a rare but
potentially detrimental complication.
Patient Saf Surg, 19;6(1):16, 2012.
Gottschalk HP, Sagoo D, Glaser D, Doan
J, Edmonds EW, Schlechter J. Biomechanical analysis of pin placement
for pediatric supracondylar humerus
fractures: does starting point, pin size,
and number matter? J Pediatr Orthop.
32(5):445-51, 2012.
Wang E, Liu T, Li J, Edmonds EW, Zhao
Q, Zhang L, Zhao X, Wang K. Does
swaddling influence developmental
dysplasia of the hip? An experimental study of the traditional straight-leg
swaddling model in neonatal rats. J Bone
Joint Surg Am, 94(12):1071-7, 2012.
Edmonds EW. Use of an absorbable plate
in the management of a clavicle fracture in an adolescent. Am J Orthop
(Belle Mead NJ), 41(1):29-32, 2012.
Eisner EA, Roocroft JH, Edmonds EW:
Underestimation of labral pathology
in adolescents with anterior shoulder
instability. J Pediatr Orthop, 32(1):427, 2012.
Register B, Pennock AT, Ho CP, Strickland CD, Lawand A, Philippon MJ.
Prevalence of abnormal hip findings
in asymptomatic participants: a prospective, blinded study. Am J Sports
Med, 40(12):2720-4, 2012.
Ellis HB, Matheny LM, Briggs KK, Pennock AT, Steadman JR. Outcomes and
revision rate after bone-patellar tendon-bone allograft versus autograft
anterior cruciate ligament reconstruction in patients aged 18 years or
younger with closed physes. Arthroscopy, 28(12):1819-25, 2012.
Jul-Aug; 33 Suppl 1: S8-S12.
Matsumoto H, Roye DP, Akbarnia BA,
Anderson RC, Brockmeyer DL, Emans
JB, Erickson M, Flynn JM, Lenke LG,
Newton PO, Nyquist AC, Richards
BS, Shah SA, Skaggs DL, Smith JT,
Sponseller PD, Sucato DJ, Zeller RD,
Saiman L. Building consensus: development of a Best Practice Guideline
(BPG) for surgical site infection (SSI)
prevention in high-risk pediatric
spine surgery. J Pediatr Orthop, 33 (5):
471-8, 2013.
2013 Mar; 55 (3): 264-70.
Schulz JF, Chambers HG. Juvenile osteochondritis dissecans of the knee:
current concepts in diagnosis and
management. Instr Course Lect, 62:
455-67, 2013.
Monazzam S, Bomar JD, Cidambi K, Kruk
P, Hosalkar H. Lateral Center-edge
Angle on Conventional Radiography
and Computed Tomography. Clin
Orthop Relat Res, 471(7):2233-7, 2013.
Proximal Rectus Femoris Release
Influence Kinematics In Patients With
Cerebral Palsy and Stiff Knee Gait?
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Am, 95 (5): e31, 2013.
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Newton PO. Is decompensation preoperatively a risk in Lenke 1C curves? Spine
(Phila Pa 1976), 38 (11): E649-55, 2013.
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Edmonds EW. Partial rotator cuff
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2-7, 2013.
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Shellington D, Khanna S. An analysis
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1/27/14 10:57 AM
Pathology
The Pathology Division is responsible for all anatomic and
clinical pathology diagnostic services and the educational
programs in pediatric pathology for medical students, residents,
and fellows. Additionally, the pathology staff contributes to and
supports an array of activities including professional societies,
public service agencies, and media productions. The pathologists
are actively engaged in collaborative research occurring within
the institution, at the University of California, San Diego (UC
San Diego) School of Medicine, and with investigators from
other institutions around the country. The pathologists are
also intimately involved in the day-to-day administrative
management of the laboratories.
pathology v4.indd 64
1/23/14 4:45 PM
FACULTY
Robert O. Newbury, MD, Director,
Clinical Professor of Pathology
Henry F. Krous, MD, Director of
Pathology Research, Clinical
Professor of Pathology
Eric Breisch, PhD, Associate Clinical
Professor of Surgery
Denise Malicki, MD, PhD, Clinical
Katayoon Shayan, MD, Associate
Clinical Professor of Pathology
Linda Ellis, MD, Associate Clinical
CLINICAL ACTIVITIES
POSTDOCTORAL
FELLOWS AND
RESIDENTS
Shouying Du
Don Xu
Parham Minoo
Nilesh Dharajiya
Alison Carrigg
Mariah Baughn
Michele McElroy
Mariana Canepa
Karra Muller
Boris Shlopov
David Li
John Nguyen
Hyun Chung
Nicole Saviano
Patrick Sweet
Rebecca Johnson
Dorothy Wong
Fang Wen
Peter Kolbalka
Jim Valentine
Evelyn Potochny
•
•
•
The Pathology Division successfully
maintained licensure by the State of
California and Federal Drug Administration (FDA), is certified by CLIA,
and maintained accreditations from
the College of American Pathologists, American Association of Blood
Banks, and the Joint Commission on
Accreditation of Hospital Organizations (JCAHO).
The pathologists serve as CAP inspectors of pathology departments at other
children’s hospitals in the U.S.
Annually, the clinical laboratory performs more than 1,500,000 tests, and
transfuses over approximately 8700
blood products to approximately 2200
patients.
LEFT TO RIGHT: Robert Newbury,
Katayoon Shayan, Denise Malicki
Pathology
65
1/27/14 10:58 AM
• Diagnostic services include bacterial
and fungal cultures, molecular diagnostic testing for infectious diseases,
routine chemistry, sweat chloride testing, glucose tolerance testing, serology, urinalysis, hematology, selected
coagulation studies, toxicology, and
blood banking.
• The Division uses polymerase chain
reaction (PCR) to identify enteroviruses, HSV, CMV, and Bordatella pertussis, which serves not only
(RCHSD), but other community hospitalsincludingNavalMedicalCenter
San Diego, Paradise Valley, Sharp Memorial,UCSanDiego,Tri-City,Palomar/Pomerado,Alvarado,Grossmont,
andNavalHospitalCampPendleton.
• The Division also participates in the
Drug Endangered Children (DEC)
Forensic Pathology Program for detecting drug exposure in children.
• TheDivisionprovideddiagnosticservices on approximately 55,000 separate surgical specimens from approximately13,000accessionedcases.
• Greater than 100 new malignancies
were identified annually.
• The pathologists performed approximately 300 frozen section diagnoses
from over 200 patients.
• Approximately20postmortemexaminations are performed annually and
the findings of many of them are presented at various medical staff conferences.
• Electron microscopy was performed
on approximately 200 specimens.
• The Division continues to provide
electronmicroscopyservicestoNaval
Medical Center San Diego.
• TheDivisionalsoprovidesrenalbiopsy consultations and interpretations
and technical support to some hospitals in San Diego County.
Eric Breisch, PhD
Morphometry of infant cranium and dura
Foreign body response to spinal implants
RESEARCH ACTIVITIES
The pathologists also teach UC San Diego surgical pathology fellows, residents,
medical students and Naval Medical
Center pathology residents who rotate
through the department.
Robert O. Newbury, MD
Eosinophilicesophagitis
Tuftingenteropathy
Hart Isaacs, Jr., MD
Neoplasiaofthefetusandearlychildhood
66
Henry F. Krous, MD
Sudden infant death syndrome (SIDS)
Sudden unexplained death in childhood
(SUDC)
Sudden death in infancy and childhood
TEACHING ACTIVITIES
The pathologists participate in numerous
educational activities including conferences and lectures within and across departments and institutions. They are:
• TumorBoard
• Neuro-OncologyTumorBoard
• NeuropathologyConference
• OtolaryngologyConference
• UropathologyConference
• OrthopedicsConference
• Gastrointestinal Pathology and Hepatic Pathology Conference
• RenalPathologyConference
• UC San Diego Pediatric Department
CPCs
• MorbidityandMortalityConferences
• UCSanDiegoSOM208HumanDisease Course
• UC San Diego SOM 213 Histology
Course
• UCSanDiegoSOMfirstyearproblem
based learning curriculum
• UC San Diego Clinical Laboratory
Scientist program lectures
• CMEcourseforDermatologicSurgeons
• Superficial Anatomy and Surgery of
theHeadandNeck
• UCSanDiegoSOMmedicalstudents
GrossAnatomy
• Head and Neck Anatomy Course,
Otolaryngology and Oral and Maxillofacial Surgery Residents
• Surgery/Radiology/Pathology Conference
• NeuromuscularPathologyConference
AWARDS, HONORS AND
MAJOR PRESENTATIONS
Henry F. Krous, MD
SIDS and Kids (Australia) Award, Baltimore, MD, October 5, 2012
Distinguished Researcher. International
Society for the Prevention of Infant
Death Achievement Award. Baltimore
MD, October 7, 2012
California Sudden Infant Death Council Syndrome Advisory Council SIDS
Lifetime Achievement Award. October30,2012,LosAngeles,CA
The Soria Moria Conference Senior InvestigatorAward.Oslo,Norway,May
28, 2012
Star of the Decade Award, The SUDC Program.NewYork,NY,April14,2012
GuildforInfantSurvivalOrangeCounty
(CA) Achievement Award, Santa Ana,
CA, 2012
Rady Children’s Hospital Pediatric Pathology Lifetime Achievement Award,
San Diego, CA, 2012
Sudden Unexpected Death in Children
(SUDC):ANewEntity–SpecialRisk
Profiles. Soria Moria Conference. SoriaMoria,Norway,May3,2012
Classification of Sudden Infant Deaths in
Infants and Small Children. A Forensic Pediatric Pathologist’s View. Soria
MoriaConference,SoriaMoria,Norway,May4,2012
Eric Breisch, PhD
AAD Annual Meeting 2012 San DiegoAnatomy of the Head and Neck for
Dermatologic Surgeons
AAD Annual Meeting 2013 Miami-
Anatomy of the Head and Neck for
Dermatologic Surgeons
Hugh Greenway’s Superficial Anatomy
and Cutaneous Surgery Course 2012
and2013.Lectures:1.SuperficialAnatomy of the Head 2. Superificial AnatomyoftheNeck3.SuperficialFascia
UCSD SOM Human Anatomy 2012. SuperficialAnatomyoftheHeadandNeck
Robert O. Newbury, MD
EosinophilicEsophagitis,anUpdate.UCSD
School of Medicine, Pathology Research
Lecture Series, December 5, 2011
Pathology
1/23/14 4:45 PM
MAJOR
GOALS &
PLANS
•
•
•
•
•
Provide anatomic and clinical
pathology consultations and services to all of the clinical programs
at RCHSD
Continue to moderate and/or
support medical staff educational, clinicopathologic, and quality
assurance conferences
Continue to serve as the pediatric
pathology training experience
for medical students, pathology
residents, and surgical pathology
fellows
Continue to support extramural
and community activities involving
professional societies and governmental agencies
Continue collaborative efforts
with investigators, particularly in
dermatology, gastroenterology,
and hematology/oncology
1/27/14 10:15 AM
What’s Under the Micropscope, EosinophilicEsophagitis,Gastroenteritisand
Colitis.PresentedatEosConnection
sponsored by American Partnership
for Eosinophilic Disorders, San Diego, CA, July 7, 2012
Teen Discussion Group: Endoscopy-
What happens while I am asleep? UndertheMicroscope.EosConnection
sponsored by American Partnership
for Eosinophilic Disorders, San Diego, CA, July 7, 2012
Denise Malicki, MD, PhD
Pediatric Pathology Osler Pathology
Board Review Course, Long Beach,
CA,February26,2013
Hart Isaacs, Jr., MD
Elected Fellow, Royal Society of Medicine, London, July 1, 2011
PUBLICATIONS
Chambers H, Shea K, Carey J. AAOS Dohil
R, Carrigg A, Newbury R. A Potential
NewMethodtoEstimateTissueCystine
ContentinNephropathicCystinosis.J
Pediatr,161(3):531-535,2012.
Du S, Scuderi R, Malicki DM, Willert J,
Bastion J, Weidner N. Hodgkin and
Non-Hodgkin lymphomas occurring
in two brothers with Wiskott-Aldrich Syndrome (WAS) and review
of the literature. Pediart Dev Pathol,
14(1):64-70,2011.
Glaser D, Farnsworth CL, Varley ES,
NunnTA,Sayad-ShahM,BreischEA,
YaszayB.Negativepressuretherapyfor
closed spine incisions: A pilot study.
WOUNDS: A Compendium of Clinical
Research and Practice.(inpress)2013.
BroderickL,GandhiC,MuellerJL,PutnamCD,ShayanK,GiclasPC,Peterson KS, Aceves SS, Sheets RM, PetersonBM,NewburyRO,HoffmanHM,
Bastian JF. Mutations of Complement
Factor I and Potential Mechanisms of
NeuroinflammationinAcuteHemorrhagic Leukoencephilitis. J Clin Immunol,33(1):162-71,2013.
Synovial chrondromatosis in a child’s
literature. Hand(NY),7(1):98-102,2012.
Inouye BM, Chiang G, Newbury RO,
Holmes N. Adolescent xanthogranu68
lomatous pyelonephritis mimicking
renal cell carcinoma on urine cytology: an atypical presentation. Urology,
81(4):885-7,2013.
Dohil R, Newbury RO, Aceves S. Transient PPI Responsive Esophageal
Eosinophilia May Be a Clinical
Sub-phenotype of Pediatric Eosinophilic Esophagitis. Dig Dis Sci, 2012
May;57(5):1413-9.
OtaniIM,AnilkumarAA,NewburyRO,
BhagatM,BeppuLY,DohilR,Broide
DH, Aceves SS. Anti-IL-5 therapy reducesmastcellandIL-9cellnumbers
in pediatric patients with eosinophilic
esophagitis. J Allergy Clin Immunol,
131(6):1576-82,2013.
CrawfordJR,NewburyRO,FriedmanJR.
An unusual presentation of posterior
fossa ependymoma in a child. BMJ
Case Rep,2013Jul5;2013
CrawfordJR,NewburyRO,LevyMLAn
unusual posterior fossa tumour in a
young child. BMJ Case Rep, 2013Jun
26,2013
Castle S, Suliman A, Shayan K, Kling K,
Bickler S, Losasso B. Total colonic
aganglionosis with skip lesions: report
of a rare case and management. J Pediatr Surg,2012Mar;47(3):581-4
Broadbelt KG, Rivera KD, Paterson DS,
Duncan JR, Trachtenberg FL, Paulo
JA,StapelsMD,BorensteinNS,Belliveau RA, Haas EA, Stanley C, Krous
HF, Steen H, Kinney HC. Brainstem
deficiency of the 14-3-3 regulator
of serotonin synthesis: a proteomics
analysis in the sudden infant death
syndrome. Mol Cell Proteomics, 2012
Jan;11(1):M111.009530.
Randall B, Donelan K, Koponen M, Sens
MA, Krous HF. Application of a classification system focusing on potential
asphyxia for cases of sudden unexpected infant death. Forensic Sci Med
Pathol,2012Mar;8(1):34-9.
ByardRW,KrousHF,RognumTO.TheSoria Moria approach to pediatric forensic
issues. Forensic Sci Med Pathol,2013.
Carter CE, Shayan K, Mak RH, Yorgin
PD, Krous HF. Nephrotic syndrome
in an 18 year old boy with congential
myelomeningocele: Questions. Pediatr Nephrol,Nov8,2012.
Carter CE, Shayan K, Mak RH, Yorgin
PD, Krous HF. Nephrotic syndrome
in an 18 year old boy with congential
myelomeningocele: Answers. Pediatr
Nephrol, Nov7,2012.
Krous HF. A commentary on changing infant death rates and a plea to
use sudden infant death syndrome
as a cause of death. Forensic Sci Med
Pathol,9(1):91-3,2013.
Trachtenberg FL, Haas EA, Kinney HC,
Stanley C, Krous HF. Risk Factor
Changes for Sudden Infant Death
Syndrome After Initiation of Back to
Back Sleep Campaign. Pediatrics,129
(4):630-8,2012.
ClarkAB,StokesTA,KrousHF,Carbine
DN.Myocardialinfarctioninanewborn heterozygous for the MTHFR
C677Tmutation.Pediatr Dev Pathol,
15(3):232-6,2012.
HolmIA,PoduriA,CrandallL,HaasE,
GrafeMR,KinneyHC,KrousHF.Inheritance of febrile seizures in sudden
unexplained death in toddlers. Pediatr
Neurol, 46(4):235-92012.
Yeh-NayreLA,MalickiDM,VinocurDN,
Crawford JR. Medulloblastoma with
excessive nodularity: radiographic
findings and pathologic correlate.
Case Rep Radiol, 2012:2012:310259.
EpubOct12,2012.
Crotty Alexander LE, Akong-Moore K,
Feldstein S, Johansson P, Nguyen A,
McEachernEK,NicatiaS,CowburnAS,
OlsonJ,ChoJY,IsaacsHJr,JohnsonRS,
BroideDH,NizetV.MyeloidcellHIF-1
alpha regulates asthma airway resistance
and eosinophil function. J Mol Med
(Berl),91(5):637-44,2013.
BroadbeltKG,PatersonDS,BelliveauRA,
Trachtenberg FL, Haas EA, Stanley
C, Krous HF, Kinney HC. Decreased
GABAAreceptorbindinginthemedullary serotonergic system in the sudden
infant death syndrome. J Neuropathol
Exp Neurol,Sep;70(9):799-810.,2011.
ByardRW,MasoumiH,HaasE,SageM,
Krous HF. Could intra-alveolar hemosiderin deposition in adults be used
as a marker for previous asphyxial
episodes in cases of autoerotic death?
J Forensic Sci,May;56(3):627-9.2011.
BOOKS
Isaacs H. Tumors of the Infant and Fetus,
AnAtlas,2ndEdition,Springer2013.
Pathology
1/23/14 4:45 PM
JOURNAL REVIEW
Journal of Pediatric Surgery
American Journal of Perinatology
Obstetrics and Gynecology
Pediatric Dermatology
Journal of Pediatric Hematology
and Oncology
Ultrasound in Obstetrics and Gynecology
Pathology-Research and Practice
Acta Paediatrica
World Journal of Pediatrics
Indian Journal of Pathology
and Microbiology
Nigerian Journal of Surgery
Pediatric and Developmental Pathology
Forensic Science, Medicine and PathologyIllinois Child Welfare
Pennock AT, Steadman JR. Outcomes
and revision rate after bone-patellar
tendon-bone allograft versus autograftanteriorcruciateligamentreconstruction in patients aged 18 years or
younger with closed physes. Arthroscopy,2012Dec;28(12):1819-25.
Jul-Aug;33Suppl1:S8-S12.
Matsumoto H, Roye DP, Akbarnia BA,
AndersonRC,BrockmeyerDL,Emans
JB, Erickson M, Flynn JM, Lenke LG,
NewtonPO,NyquistAC,RichardsBS.,
Shah SA, Skaggs DL, Smith JT, Sponseller PD, Sucato DJ, Zeller RD, Saiman
L. Building consensus: development of a
Best PracticeGuideline (BPG) forsurgical site infection (SSI) prevention in
high-risk pediatric spine surgery. J Pediatr Orthop, 2013Jul-Aug;33(5):471-8.
2013Mar;55(3):264-70.
SchulzJF,ChambersHG.Juvenileosteochondritis dissecans of the knee: current concepts in diagnosis and management. Instr Course Lect, 2013Feb;
62:455-67.
Monazzam S, Bomar JD, Cidambi K, Kruk
P, Hosalkar H. Lateral Center-edge
Angle on Conventional Radiography
andComputedTomography.Clin Orthop Relat Res,2013Jul;471(7):2233-7.
Proximal Rectus Femoris Release Influence Kinematics In Patients With
Cerebral Palsy and Stiff Knee Gait?
Clin Orthop Relat Res,2013Jun28.
Am,2013March;95(5):e31.
DemuraS,YaszayB,BastromTP,Carreau
J,NewtonPO.Isdecompensationpreoperatively a risk in Lenke 1C curves?
Spine(PhilaPa1976),2013May15;38
(11):E649-55.
knowledge in osteochondritis dissecans: 123 years of minimal evolution
from Konig to the ROCK study group.
Clin Orthop Relat Res, 2013Apr;471
(4):1118-26.
Edmonds EW, Shea KG. Osteochondritis dissecans: editorial comment. Clin
Orthop Relat Res, 2013 Apr; 471 (4):
1105-6.
obesity and musculoskeletal problems:
editorial comment. Clin Orthop Relat
Res, 2013Apr;471(4):1191-2.
Eisner EA, Roocroft JH, Moor MA, EdmondsEW.Partialrotatorcufftearsin
adolescents: factors affecting outcomes.
J Pediatr Orthop, 2013Jan;33(1):2-7.
Pennock AT, Herzog MM, Briggs KK,
Ho CP. Relationship between femoral
anteversion and findings in hips with
femoroacetabular impingement. Orthopedics, 2013March;36(3):e293-300.
FornariED,SuszterM,RoocroftJ,Bastrom
T, Edmonds EW, Schlechter J. Childhood obesity as a risk factor for lateral
condyle fractures over supracondylar
humerus fractures. Clin Orthop Relat
Res,2013Apr;471(4):1193-8.
Shellington D, Khanna S. An analysis
in pediatric trauma patients: ten-year
experience of a level I pediatric trauma center. J Trauma Acute Care Surg,
2013Apr;74(4):1102-7.
GottschalkHP,BastromTP,EdmondsEW.
Reliability of internal oblique elbow radiographs for measuring displacement
of medial epicondyle humerus frac-
tures: a cadaveric study. J Pediatr Orthop, 2013Jan;33(1):26-31.
What’s new in pediatric orthopaedics.
J Bone Joint Surg Am,2013Feb;95(4):
377-83.
Newton,PO.Lenke1Cand5Cspinal
1976),2013Apr15;38(8):650-8.
LarkRK,YaszayB,BastromTP,Newton
PO. Adding thoracic fusion levels in
Lenke 5 curves: risks and benefits.
Spine(PhilaPa1976),2013Jan15;38
(2):195-200.
MillettPJ,HoranMP,PennockAT,Rios
Management (CAM) procedure: clinical results of a joint-preserving arthroscopic treatment for young, active
patients with advanced shoulder osteoarthritis. Arthroscopy,2013March;
29(3):440-8.
Monazzam S, Bomar JD, Dwek JR, HosalkarHS,PennockAT.Development
and prevalence of femoroacetabular
impingement-associated morphology
in a paediatric and adolescent population:aCTstudyof225patients.Bone
Joint J,2013May2;95-B(5):598-604.
Newton PO, Marks MC, Bastrom TP,
Betz R, Clements D, Lonner B, Crawford A, Shufflebarger H, O’Brien M,
YaszayB.SurgicaltreatmentofLenke
1 main thoracic idiopathic scoliosis:
results of a prospective, multicenter
study. Spine(PhilaPa1976),2013Feb
15;38(4):328-38.
Pathology
69
1/23/14 4:45 PM
Surgery &
Trauma
The Division of Pediatric Surgery at Rady Children’s Specialists
of San Diego (RCSSD) provides care to infants, children and
adolescents with surgical diagnoses. These diagnoses include
congenital anomalies, abdominal and thoracic surgical diseases,
solid tumors, organ transplantation and trauma. The Division
provides surgical operative care for approximately 3,000 patients
a year. The Division provides hospital and office consultations
and prenatal consultations for congenital disorders. All members
of our board are certified in Pediatric and General Surgery.
The Division of Pediatric Surgery continues to be a leader in
minimally invasive procedures for children. Greater than ninetyeight percent of appendectomies are performed laparoscopically.
Dr. Timothy J. Fairbanks, has continued to emphasize single
site and minimally invasive procedures which result in essentially
scarless operations. Advanced minimally invasive procedures
are routinely performed in the chest and abdominal cavities on
patients of all sizes. Difficult surgical procedures such as partial
splenectomies, adrenalectomies and ovarian procedures can
be performed with the benefits of less scarring, less pain and
quicker return to full activities. Dr. Fairbanks has also helped
organize the Division’s efforts to initiate a Pediatric Surgical
fellowship training program. He is the Program Director for the
training program.
surgery and trauma v3.indd 70
1/23/14 4:43 PM
Dr. Nicholas Saenz has special expertise and interest in Pediatric
Surgical Oncology. He is a member of the Society of Surgical
Oncology. He is the representative for the American College of
Surgeons, and a member of the Emergency Medical Services for
Children Trauma Advisory Committee for California.
Dr. Karen Kling has been instrumental in designing, developing
and implementing surgical applications for EPIC, the electronic
health record at RCHSD.
Dr. Stephen Bickler is an international expert in establishing
pediatric surgical care in developing nations. He is a leader for the
multi-center NIH grant supporting these efforts.
Dr. Julia Grabowski joined the Division in September 2012. She
is a skilled pediatric surgeon and is collaborating with Dr. Chiang on
an EPIC based research projects regarding appendicitis & regarding
ovarian cysts. She is the Assistant Training Program Director.
Dr. Mary Hilfiker is the Trauma Medical Director & Division
Director.
RCHSD is the only American College of Surgeons nationally
designated Level 1 pediatric trauma center in
San Diego and Imperial counties. The hospital
and division also receive injured children
from the surrounding areas including
Riverside County.
The trauma center cares for over
1000 patients a year who have been
designated as trauma patients.
Since the inception of the trauma
system sin San Diego in 1984, the
trauma service at RCHSD has cared
for approximately 30,000 children.
The trauma service is nationally
recognized for disaster preparedness
and planning and is working with the
CDC on disaster plans.
FACULTY
Stephen W. Bickler, MD, Clinical
Professor of Surgery and Pediatrics,
UCSD
Timothy Fairbanks, MD, Assistant
Julia E. Grabowski, MD, Assistant
Mary L. Hilfiker, PhD, MD, MMM,
Clinical Professor of Surgery, UCSD,
Division Director, Trauma Medical
Director
Karen M. Kling, MD, Associate
Nicholas C. Saenz, MD, Clinical
Janelle De la Vina, NP
LEFT TO RIGHT: Timothy Fairbanks,
Julia Grabowski, Stephen Bickler,
Karen Kling, Nicholas Saenz
Surgery & Trauma
71
1/27/14 11:01 AM
CLINICAL ACTIVITIES
Trauma
The top three causes of serious injury to
children seen in San Diego are falls, motor vehicle crashes and pedestrian versus
motor vehicle injuries.
In addition to clinical care, the trauma
service members work to help families
prevent injuries by sharing current trends
via the RCHSD website, participating
in media events and distributing educational materials such as one-page information sheets on a variety of injury prevention topics. Areas of special concern
and focus for the past few years include
of pedestrians struck by motor vehicles,
drowning and children injured by falling
televisions.
The trauma center was re-certified by
the American College of Surgeons as a
Level 1 Pediatric Trauma Center in 2012.
Pediatric Surgery
The Division work closely with the oncologists in the care of children with cancer
and with the neonatologists and perinatologists in the care of newborns
with congenital anomalies.
Division members are always available
to provide immediate care for trauma patients and any urgent or emergent surgical problems. They are also involved in
teaching the surgical residents, pediatric
residents, medical students and nurses.
We are actively involved in establishing
an ACGME accredited pediatric surgery
training program. In addition, general
surgery residents from UCSD and The
Naval Medical center are joining us to
learn pediatric surgery & trauma.
RESEARCH ACTIVITIES
Dr. Bickler does research involving disease patterns in developed and developing countries.
The Trauma Service conducts multiple epidemiologic studies and is actively
involved in research projects with the
Intensive Care and Emergency Medicine
Fellows. These include research regarding
the value of repeat imaging for head injuries, frequency of repeat imaging and use
72
of hypertonic saline in concussion and
complications of hypertonic saline use.
TEACHING ACTIVITIES
The Division of Pediatric Surgery has
initiated a Pediatric Surgery fellowship
training program through the UCSD
Graduate Medical Education office. This
program has begun training our first fellow, Katherine P. Davenport, MD. The
training program is in the process of obtaining ACGME approval and hopes to
train one fellow per year. The process of
becoming a Pediatric Surgeon is one of
the most rigorous in all of medical training. We look forward to training future
pediatric surgeons.
The educational program within the
Division of Pediatric Surgery has been
enhanced over the last few years. General
Surgery Residents from both the UCSD
and Navy General Surgery departments
rotate on service for a full year. There is
a regular basic science conference weekly. The general surgery service has at
least one case conference per week and
occasionally more. Multidisciplinary
conferences with specialties such as Neonatology, Pathology and Radiology now
occur and allow organized communication about mutual patients. Dr. Nicholas
Saenz is a site clerkship mentor for 3rd
year medical students.
All of the Surgery Division members
participate in teaching residents and
students from UCSD in addition to providing education for nursing and staff at
RCHSD. All are members of RCSSD with
faculty appointments at UCSD.
All of the Surgery Division members
are trauma surgeons also and involved
in ongoing education and performance
improvement. They also collaborate with
adult trauma centers in San Diego and the
County of San Diego Emergency Medical
Services in these endeavors.
Dr. Stephen Bickler is a consultant for
the World Health Organization and travels internationally to teach and care for
children with surgical disorders.
AWARDS, HONORS AND
MAJOR PRESENTATIONS
Stephen W. Bickler, MD
Kieswetter Lectureship, University of
Pittsburgh Children’s Hospital, 2011
Oregon Health Science University, Department of Surgery, Alumnus of the
Year, 2012
Invited Speaker Royal Australasian College of Surgeons, Melbourne 2012
Fulbright Scholarship, Mozambique,
2013
Invited Speaker International Surgical Society, Helsinki, Finland, August 2013
Election to American Surgical Association
Nicholas C. Saenz, MD
San Diego Magazine Top Doctor, 2009,
2010, 2011, 2012
Oncology Fellow Lecture Series, 2009
ALS graduate training Class, 2009, 2010,
2011
Best Doctor in San Diego, 2011, 2013
RN Residency Lectures 2009, 2010, 2011
EMS-C California Trauma Advisory
Committee
Karen M. Kling, MD
American’s Top Surgeons 2008, 2010
Best Doctor’s in America 2009, 2010,
2011, 2013
Cares Award, 2011
Course Director Pediatric Surgery
Sub-Internship 2007-present
Champion–Pediatric Surgery block
2006-present (core medical school
surgical clerkship)
Champion–Pediatric Surgery resident
education 2006-present
Pediatric IBD Consortium 2009-present
EPIC/Information Technology Committee 2008-present
Pediatric IBD (inflammatory bowel disease) Consortium to address and evaluate potential avenues for investigation
Abdominal Solid Organ Transplant
Committee 2006-present
Mary L. Hilfiker, MD
Best Doctors 2010, 2011, 2012, 2013
Board of Directors, Trauma Center Association of America
Board of Directors, ACS-PA, PAC Board
Surgery & Trauma
1/23/14 4:44 PM
Timothy J. Fairbanks, MD
Top Docs San Diego Magazine 2012, 2013
Best Doctor 2013
Pediatric Surgery Fellowship Program
Director 2012 - Current
Penetrating Neck Trauma, San Diego Pediatric Emergency Medicine Regional
Conference, February 14, 2013
Surgical Repair of Chest and Abdominal
Abnormalities, Perinatal Diagnosis
Conference 2013
PUBLICATIONS
Gonda DD, Meltzer HS, Crawford JR,
Hilfiker ML, Shellington DK, Peterson
BM, Levy ML. Complications Associated With Prolonged Hypertonic Saline Therapy in Children With Elevated Intracranial Pressure. Pediatr Crit
Care Med, 14(6):610-620, 2013.
Bickler SW, De Maio A. Dysfunction of
the innate immune system during
sepsis: a call for research. Crit Care
Med, 41(1): 364-365, 2013.
Bickler SW, McQueen K. Proceedings of
the 4th annual meeting of the Alliance
for Surgery and Anesthesia Presence
(ASAP): Building sustainable surgical
systems. World J Surg, 37(7): 14601461, 2013.
Bickler SW, Ring J, et al. Sulfur amino
acid metabolism limits the growth
of children living in environments
of poor sanitation. Med Hypotheses,
77(3): 380-382, 2011.
Castle S, Suliman A, Lossaso B, Bickler
SW, Total colonic aganglionosis with
skip lesions: report of a rare case and
management. J Pediatr Surg, 47(3):
581-584, 2012.
Cauvi DM, Song D, Vazquez DE, Hawisher D, Bermudez JA, Williams MR,
Bickler S, Coimbra R, De Maio A. Period of irreversible therapeutic intervention during sepsis correlates with phase
of innate immune dysfunction. J Biol
Chem, 287(24): 19804-19815, 2012.
Chang DC, Anderson JE, Kobayashi L,
Coimbra R, Bicker SW. Projected lifetime risks and hospital care expenditure for traumatic injury. J Surg Res,
176(2): 567-570, 2012.
Iddriss A, Shivute N, Bickler S, Cole-Ceesay R, Jargo B, Abdullah F, Cherian M.
Emergency, anaesthetic and essential
surgical capacity in the Gambia. Bull
World Health Organ, 89(8): 565-572,
2011.
Lazar DA, Cohen SA, Evora DK, Losasso BE, Bickler SW. Cecal bascule in a
child: an unusual cause of postoperative bowel obstruction. J Pediatr Surg,
47(3): 609-611, 2012.
Ramirez M, Chang DC, Bickler SW. Pediatric injury outcomes in racial/ethnic minorities in California: diversity
may reduce disparity. JAMA Surg,
148(1): 76-80, 2013.
Spiegel DA, Abdullah F, Price R, Gosselin
R, Bickler SW. World health organization global initiative for emergency
and essential surgical care: 2011 and
beyond. World J Surg, 37(7): 14621469, 2013.
Anderson JE, Lassiter R, Bickler SW, Talamini MA, Chang DC. Brief tool to
measure risk-adjusted surgical outcomes in resource-limited hospitals.
Arch Surg, 147(9):798-80, 2012.
Anderson JE, Bickler SW, Chang DC,
Talamini MA. Examining a common disease with unknown etiology:
trends in epidemiology and surgical management of appendicitis in
California, 1995-2009. World J Surg,
36(12):2787-94, 2012.
Drummond R, Cauvi DM, Hawisher D,
Song D, Niño DF, Coimbra R, Bickler
SW, De Maio A. Deletion of scavenger receptor A gene in mice resulted
in protection from septic shock and
modulation of TLR4 signaling in isolated peritoneal macrophages. Innate
Immun, 19(1):30-41, 2013.
Grabowski J, Vazquez DE, Costantini T,
Cauvi DM, Charles W, Bickler SW,
Talamini MA, Vega VL, Coimbra R,
De Maio A. Tumor necrosis factor expression is ameliorated after exposure
to an acidic environment. J Surg Res,
173(1):127-34, 2012.
Montesa C, Fairbanks T, Kling K, Chang
DC, Bickler SW. Evaluating Minimally Invasive Surgery from a Public
Health Perspective. Southern California
American College of Surgeons Program,
abstract p 73, 2011.
Castle S, Kling K, Bickler SW, LoSasso B.
Long Segment Hirschprung Disease
with Skip Lesions: Report of a Rare Case
and Management. Southern California
American College of Surgeons Program,
abstract p 79, 2011.
Chiang G, Fairbanks T, Initial use of LESS
for the ACE Malone procedure in children. Urology, 80(3):717-8, 2012.
Prasad R, Arthur LG, Timmapuri SJ, Schwartz
MZ, Fairbanks TJ, Mendelson KG, Thatch
K, Moront ML, Early experience with single-incision thoracoscopic surgery in the
pediatric population. J Laparoendosc Adv
Surg Tech A, 21(2):189-92, 2011.
Books:
Bickler SW, Ameh E (Eds). Surgical Care
For Children: Guidelines For The Primary
Referral Hospital. MacMillan Publishers.
2011.
Ameh E, Bickler S, Lakhoo K, Nwomeh B,
Poenaru D (Eds). Pediatric Surgery: A
Comprehensive Text For Africa. Global
Help, 2011.
Surgery & Trauma
73
1/23/14 4:44 PM
Pediatric Urology
The Division of Pediatric Urology focuses on all aspects of
genitourinary disorders encountered in children from birth
through young adulthood. These varied conditions encompass
treatment with both medical and surgical regimens.
The Division has been honored since 2009 by being ranked
in Pediatric Urology care by U.S. News & World Report’s
“America’s Best Children’s Hospital.” Its most recent ranking in
2013 was #10 and continues to be the highest ranked program
in the state of California; thus, reinforcing the world class care
our patients are receiving at Rady Children’s Hospital-San Diego
(RCHSD) in conjunction with Rady Children’s Specialists of San
Diego (RCSSD).
urology v4.indd 74
1/23/14 5:30 PM
FACULTY
NURSE PRACTITIONERS
RESEARCH ACTIVITIES
Nicholas M. Holmes, MD, MBA Chief,
Division of Pediatric Urology,
George W. Kaplan, MD, MS, FAAP,
FACS, Distinguished Clinical Professor of Surgery and Pediatrics, UCSD
Madhu Alagiri, MD, Clinical Professor
of Surgery, UCSD
George Chiang, MD, Associate Clinical
Sarah Marietti, MD, Assistant Clinical
Ann Marie Berger Finley, MSN, FNP
Queyn Nguyen, CPNP
Dr. Chiang is leading the way for clinical research in our Division. As part of
our commitment to investigating cutting
edge therapeutics and improving the
quality of care for our patients, we are
actively involved in several clinical trials.
By partnering with the biomedical industry, we are investigating novel forms of
medications for children with neurogenic
bladder. Two clinical trials involving
new medical therapy to treat neurogenic
detrusor overactivity in children performing intermittent catheterization
were completed in 2013. He served as the
principal Investigator in a study entitled,
“A Multi-Center, Double-Blind, Place-
FELLOWS
Puneeta Ramachandra, MD, Fellow,
Pediatric Urology (2011-2013)
Gina Cambareri, MD, Fellow Pediatric
Urology (2013-2015)
CLINICAL ACTIVITIES
Over 9,000 patient visits per year were
conducted in the Pediatric Urology
Clinic in its main office on the campus of
RCHSD and at its satellite clinics in Encinitas, Escondido, North County Coastal
and Murrieta during 2011-2013. We have
expanded our multi-disciplinary clinics
besides the Spinal Defects Clinic which
has been in existent for many years. In
addition, we have created a Stone Clinic
with our Nephrology colleagues which
focus on the medical and surgical management of urinary stone disease. During
the same time frame, over 3,000 surgical
procedures per year were performed.
LEFT TO RIGHT: Gina Camberreri,
Madhu Alagiri, Tami Rechen,
Sarah Marietti, Ann Marie Berger Finley,
George Kaplan, Quyen Nguyen,
Nicholas Holmes, George Chiang
Pediatric Urology
urology v4.indd 75
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1/27/14 11:04 AM
bo-Controlled, Dose-Titration Study
Evaluating the Efficacy, Safety, Pharmacodynamics and Pharmacokinetics of
Oxybutynin Chloride Topical Gel for
the Treatment of Detrusor Overactivity
Associated with a Neurological Condition in Pediatric.”
Also, Dr. Chiang received UCSD Academic Senate Research Grant of $10,000
for basic science project involving the
development of minimally invasive micturition animal model. He also received
additional grant funding of $10,000 from
RCSSD Physician’s Development Fund
for research relating to strategic collaboration project for inquiry of pediatric
electronic health information systems.
Dr. Marietti in conjunction with
Dr. Holmes are creating and designing
a database to retrospectively and prospectively categorize patients who have
vesicoureteral reflux. Specifically, they
hope to address issues concerning surgical outcomes and quality indicators in the
treatment of this disease.
TEACHING ACTIVITIES
The Division of Pediatric Urology continues our commitment to
graduate medical education training with
its ACGME accredited fellowship. Since
its inception in 1985, Dr. George Kaplan
has been and continues to act as program
director. .. Dr. Puneeta Ramachandra has
completed her fellowship in June 2013
and has joined the faculty at Children’s
Hospital Central California. Dr. Gina
Cambareri is our current clinical fellow
who began the fellowship in July 2013.
The Division of Urology participates
in the following teaching activities:
• UrologyresidentsfortheNavalMedical Center San Diego (NMCSD) and
UCSD rotate on the service throughout the academic year
• MonthlyClinicalCaseGrandRounds
held jointly with NMCSD, UCSD and
RCHSD
• Biweekly Uroradiology conference
with radiology, pediatric urology and
pediatric nephrology faculty
• Biweeklytutorialsessionsforresidents,
fellows and faculty in pediatric urology
76
• Monthly Uropathology conference
with pathology and pediatric urology
faculty
• Monthly journal club with review of
the pediatric urology literature
• Annual Grand Rounds held by the
UCSD Division of Urology for the
greater San Diego urologic community
• Participation in the “Noon Lecture
Series” for UCSD Department of
Pediatric residents and trainees
In addition, Drs. Holmes and Chiang
have continued to support undergraduate and medical students via Dr. Holmes’
participation in the Health Professionals
Mentor Program and Dr. Chiang’s participation in Project Nicaragua.
AWARDS, HONORS AND
MAJOR PRESENTATIONS
Nicholas M. Holmes, MD, MBA
Reviewer for the Journal of Urology,
Section of Pediatric Urology
Member, Quality Improvement Committee, RCHSD
Member, Medical Staff Executive Committee, RCHSD
Member, Kidney Transplant Committee,
RCHSD
Member, Surgery Executive Committee,
RCHSD
Member, Foundation Board of Trustees,
RCHSD
Member, Quality, Safety and Medical
Affairs, Committee, RCHSD
Member, Clinical Information Advisory
Council, RCHSD
Chair, Department of Surgery, RCHSD
Chief, Section of Urology, RCHSD
Medical Director, Clinical Documentation Improvement and ICD-10
Transition, RCHSD
Medical Director, Surgical Services, RCHSD
Chair, Joint Quality/Credentialing Committee RCSSD
Member, Board of Governance Committee,
RCSSD
Member, Board of Directors, YMCAYouth and Family Services
American Health Information Management
Association (AHIMA) ICD-10 Summit
Assuring a Solid ICD-10 Foundation
through a Physician Engagement in
Clinical Documentation, April 16,
2012, Baltimore, MD
Pediatric Urology
urology v4.indd 76
1/23/14 5:30 PM
George W. Kaplan, MD, MS, FAAP, FACS
Reviewer for the Journal of Urology, Pediatrics, and Journal of Pediatric Surgery
Chair, Transplant Committee, RCHSD
Examiner, American Board of Urology
Selected for inclusion in Who’s Who in
America (68th Edition)
Honorable Mention in an article Who’s
Who in Health and Medicine by J
Bozanek, in News Digest International
Health and Medical Merit Award from
News Digest International, 2013
Included in Guide to America’s Top
Surgeons, 2013
Included in Best Doctors in America, 2013
Listedin2011SanDiegoSuperDoctors
1st Place WSAUA History Essay: Peter
Remondino-The Man, His Book and
His Library, presented November,
2013 in Monterey, CA
Faculty Presenter, Update on Bladder
and Bowel Dysfunction, (BBD), and
Education Special Interest Group.
Pediatric Urology Nurse Specialists,
American Academy of Pediatrics
Annual Conference, New Orleans,
LA,October12,2012
UCSD Pediatric Grand Rounds,Bladder
and Bowel Dysfunction in Children,
February 2013
Podium Presentation, Society of Urologic Nurses and Associates Annual
Conference,Bladder and Bowel Dysfunction in the Pediatric Population,
March 2013
American Urological Association, Pediatric Urology Nurse Specialists Annual
Meeting, Chair of Special Interest
Group Bowel Bladder Dysfunction
Education May 2013
George Chiang, MD
Member, Special Emphasis Panel for the
CDC regarding funding for National
Spina Bifida Registry
Moderator and Presenter for Hispanic
Educational Forum: Spina Bifida
Association
National Meeting Anaheim, CA, 2011
Member, Board of Director San Diego
Spina Bifida
Poster presentation, Bilateral Laparo-endoscopic Single Site Nephrectomy:
a Pediatric Pretransplant Possibility,
Society of American Gastrointestinal
and Endoscopic Surgeons (SAGES)
Annual Meeting, San Antonio, TX 2011
UCSD Urology Faculty Educator Award,
2013
U.S. News & World Report, Top Doctors,
2013
Clinical Research Finalist, 2 Sessions of
Behavioral Urotherapy. Society of
Pediatric Urology World Congress
Meeting, San Diego, CA, May 2013
Moderator, Spina Bifida: Urology PhysiologyandTreatment,SpanishLanguage
LectureSeries38thSpinaBifidaAssociation Annual Meeting Anaheim, CA,
June 2011
PUBLICATIONS
Ann Marie Berger Finley, MSN, FNP
Member-at-Large, Society of Urologic
Nursing and Associates Catheterization task Force for Pediatric Protocol
Development
Sparks S, Kaplan A, Decambre M, Kaplan
G, Holmes N. Eosinophilic cystitis in
the pediatric population: a case series
and review of the literature. Journal of
Pediatric Urology, 2013 February 4.
Bundenthal S, Belley S, Comfort A,
Holmes N. et al. Guidelines for achieving a compliant query practice. Journal
of AHIMA, 84 (2):50-53, 2013.
Ramachandra P, Palazzi K, Skalsky A,
Marietti S, Chiang G. Shunted hydrocephalus has a significant impact on
quality of life in children with spina
bifida. PM&R, May 22nd 2013, S19341482.
Colangelo CJ, Kaplan GW, Holmes N,
Palazzi-Churas K, and Chiang G. Ureteroscopy in Pediatric Patients with
Spinal Abnormalities. J Endourology
2013 May; 27(5):545-8
Inouye, BM, Chiang G, Holmes N.
Adolescent
Xanthogranulomatous Pyelonephritis Mimicking Renal
Cell Carcinoma on Urine Cytology:
An Atypical Presentation. Urology,
81(4):885-7, 2013.
Woo J, Sisul D, Kaplan G, Chiang G.
Urologic outcomes of pediatric pelvic
neuroblastoma presenting in acute
urinary retention. Pediatric Hematology and Oncology, 2013 (in press).
Woo J, Marietti S, Masterson J, Chiang G.
Minimal incision laparoscopy assisted
open pediatric pyeloplasty. Journal of
Pediatric Urology, 2013 (in press).
Kaplan GW. Urethral Strictures in Children.
Curr Opin Urol, 22:462-466, 2012.
Marietti S, Woldrich J, Durbin J, Sparks S,
Kaplan G, Chiang G. Urologic findings
on computed tomography of the abdomen and pelvis in a pediatric population.
J Pediatr Urol, 2012 Jun 20.
Alagiri M. Diagnosis and Management of
Megaureter, Ectopic Ureter, Reflux, and
Ureterocele. Urology Pearls of Wisdom,
4th Edition. Boston Medical Publishing
Corp.Editor.DavidA.Levy.2012.
Chiang G, Fairbanks T. Initial Use of LESS
for the ACE Malone Procedure in Children. Urology, 2012 Mar 31.
Sparks S, DeCambre M, Christman M,
Kaplan G, Holmes N. Salvage ureteral
re-implantation following failure of
dextranomer/hyaluronic acid injection.
Journal of Urology, 186: 257-260, 2011.
Marietti S, Holmes N, Chiang G. Laparoendoscopic single-site (LESS) bilateral
nephrectomy in pretransplant pediatric
population. Pediatric Transplantation, 15
(4): 396-399, 2011.
Woldrich J, Holmes N, Palazzi-Churas K,
Alagiri M, Decambre M, Kaplan G, Chiang G. Comparison of laparoendoscopic
single-site, conventional laparoscopy, and
open nephrectomy in a pediatric population. Urology, 78(1): 74-77, 2011.
Marietti S, Decambre M, Fairbank T, Kling K,
Chiang G. Early experience with laparoendoscopicsingle-sitesurgery(LESS)inthe
pediatric urology population. Journal of
Endourology, 24 (8): 1321-1324, 2010.
Chalmers D, Marietti S, Kim C. Xanthogranulomatous pyelonephritis in an
adolescent. Urology, 76(6) 1472, 2010.
Hackett L, Tarsa M, Wolfson T, Kaplan G,
Vaux K, Pretorius D. Use of multi-planar
3-dimensional ultrasonography for prenatal sex identification. Journal of Ultrasound
Medicine, 29:195-202, 2010.
FLIP BOOK
TO READ
THE DEPARTMENT
OF PEDIATRICS
BIENNIAL REPORT
Pediatric Urology
urology v4.indd 77
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1/23/14 5:30 PM
BIENNIAL REPORT 2011-2013 DEPARTMENT OF PEDIATRICS
DEPARTMENT OF CHILDREN’S SURGERY
1/23/14 1:30 PM
Surgery cover v2.indd 3

Department of Children`s Surgery - Rady Children`s Hospital

Transcription

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