lampiran 2 senarai pemegang geran jangka pendek usm tahun 2008
Transcription
lampiran 2 senarai pemegang geran jangka pendek usm tahun 2008
|| LAPORAN TAHUNAN 2008 || SENARAI KANDUNGAN Bil Tajuk m/surat SENARAI KANDUNGAN ................................................................................................................ i SENARAI RAJAH ................................................................................................................ ii SENARAI JADUAL ................................................................................................................ iii PRAKATA DEKAN PENYELIDIKAN SAINS KLINIKAL ........................................................................ iv 1. 2. 3. PENGENALAN ……………………………………………………........................................................................ 01 OBEJKTIF DAN FUNGSI ………………...……………………….................................................................... 01 STRUKTUR PENGOPERASIAN …...…...……………………….............................................................. 01 3.1 Carta Organisasi ………………………………………….............................…………….......................... 02 3.2 Struktur Pengoperasian 3.3 Jawatankuasa Teknikal Penyelidikan ‐ Sains Klinikal (JKTP) ......................................... 04 3.4 Jawatankuasa Etika Penyelidikan (Manusia) – (JEPeM) ......................................... 05 ….………………………...........……………….....................…................... 03 4. GERAN PENYELIDIKAN ...........................................…...........……....…........................................…. 07 4.1 Geran Jangka Pendek USM .................................................................................................. 10 4.2 Geran Universiti Penyelidikan ................................................................................................ 11 4.3 Geran Science Fund ................................................................................................................ 11 4.4 Geran Insentif ......................................................................................................................... 12 4.5 Kajian Klinikal Kontrak (Contract Clinical Trials) ..................................................................... 12 5. 6. 7. 8. AKTIVITI PELANTAR SAINS KLINIKAL, KAMPUS KESIHATAN TAHUN 2008 ..................................... 16 OUTPUT PENYELIDIKAN ................................................................................................................. 19 RUMUSAN ................................................................................................................................ 19 LAMPIRAN ............................................................................................................................... 20 Lampiran 1 ‐ Lampiran 2 ‐ Lampiran 3 ‐ Lampiran 4 ‐ Senarai Permohonan dinilai dalam Mesyuarat Jawatankuasa Etika Penyelidikan (Manusia) 2008 ............................................................................... 21 Senarai Pemegang Geran Jangka Pendek USM 2008 ........................................... 32 Senarai Pemegang Geran Penyelidikan Universiti 2008 ....................................... 36 Output Penyelidikan 2008 ..................................................................................... 40 | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | i || LAPORAN TAHUNAN 2008 || SENARAI RAJAH Bil Tajuk Rajah m/surat Rajah 1.0: Struktur Organisasi Pelantar Penyelidikan, Kampus Kesihatan ........................................ 02 Rajah 1.1: Struktur Pengoperasian Pelantar Penyelidikan, Kampus Kesihatan ................................. 03 SENARAI CARTA Bil Tajuk Carta m/surat Carta 1: Carta 2: Carta 3: Carta 4: Carta 5: Jumlah Permohonan Kelulusan Etika Penyelidikan Klinikal Tahun 2008 …………………..…… 08 Jumlah Permohonan Kelulusan Etika Penyelidikan Klinikal Tahun 2008 Mengikut Jenis Geran …………....................................................................................... 09 Jumlah Peruntukan Geran Penyelidikan USM diperolehi Mengikut Jenis Geran ………….. 10 Geran Jangka Pendek USM diluluskan Mengikut Pusat Pengajian ............................…….. 10 Geran Universiti Penyelidikan Aktif bagi Tahun 2008 Mengikut Pusat Pengajian ………….. 11 | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | ii || LAPORAN TAHUNAN 2008 || SENARAI JADUAL Bil Jadual 1.0: Jadual 1.1: Jadual 1.2: Jadual 1.3: Jadual 1.4: Jadual 1.5: Jadual 1.6: Jadual 1.7: Jadual 1.8: Jadual 1.9: Jadual 2.0: Jadual 2.1: Jadual 2.2: Jadual 2.3: Jadual 2.4: Jadual 2.5: Tajuk Jadual m/surat Senarai Ahli Jawatankuasa Teknikal Penyelidikan 2008 .................................................. 04 Tarikh Mesyuarat Jawatankuasa Teknikal Tahun 2008 ………........................................... 04 Permohonan Geran Penyelidikan yang dinilai oleh Mesyuarat JKTP 2008 ..................... 05 Senarai Ahli Jawatankuasa Etika (JEPeM), (Sehingga Oktober 2008) ........................ 05 Senarai Ahli Jawatankuasa Etika (JEPeM), (Bermula November 2008) ………................. 06 Permohonan yang dinilai dalam Mesyuarat Jawatankuasa Etika Penyelidikan (Manusia) 2008 Mengikut Bulan ................................................................. 07 Pecahan Permohonan Kelulusan Etika Mengikut Pusat Tanggungjawab (PTJ) ........... 08 Bilangan Kertas Cadangan Penyelidikan dibentang dalam Mesyuarat Expedited Review …………………………....................................................... 09 Bilangan Geran USM Jangka Pendek Diluluskan Mengikut Pusat Pengajian 2008 ........... 10 Geran Aktif Science Fund 2008 ................................................................................... 11 Jumlah Permohonan mengikut Kategori Bidang Kajian (Science Fund)............................. 11 Geran Insentif Diluluskan 2008 …………………………………………….................................... 12 Senarai Geran Kajian Klinikal Kontrak Tahun 2008 ….................................................... 12 Senarai Aktiviti Pelantar Penyelidikan Klinikal Tahun 2008 ........................................ 16 Senarai Output Mengikut Pusat Pengajian bagi Tahun 2008 ......................................... 19 Senarai Rumusan Fakta dan Nombor Mengenai Aktiviti Pelantar Penyelidikan Sains Klinikal 2008 ........................................................................... 19 | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | iii || LAPORAN TAHUNAN 2008 || PRAKATA Syukur Alhamdullilah, kami dapat melengkapi laporan tahunan ini. Laporan ini mengandungi pelbagai hal berkaitan aktiviti‐aktiviti Penyelidikan Sains Klinikal sepanjang 2007. Walau bagaimanapun, laporan ini tidaklah ‘absolute’ kerana aktiviti‐aktiviti kami agak bertindih dengan Pelantar Penyelidikan Sains Kesihatan & Bioperubatan. Laporan ini memuatkan pencapaian perolehan geran penyeldikan mengikut Pusat Tanggung‐Jawab (PTJ), pencapaian aktiviti‐aktiviti Jawatankuasa Etika Penyelidikan Manusia (JEPeM) and Jawatankuasa Teknikal Penyelidikan. Kami telah memasukkan juga senarai aktiviti berkaitan penyelidikan seperti seminar dan konferens yang secara umumnya bukan dianjurkan oleh Pejabat Pelantar Penyelidikan Sains Klinikal tetapi oleh pusat tanggungjawab di Kampus Kesihatan untuk melengkapkan lagi laporan ini. Kami juga memuatkan senarai penerbitan oleh pensyarah‐pensyarah di pusat tanggungjawab seperti Pusat Pengajian Sains Perubatan, Pusat Pengajian Sains Kesihatan, Pusat Pengajian Sains Pergigigan, Pusat Pengajian Sains Farmasi, Hospital Universiti Sains Malaysia, Institut Perubatan dan Pergigian Termaju dan juga Institut Perubatan & Penyelidikan Molekul. Data ini diperolehi dari pelbagai sumber, seperti laporan akhir, laman web PTJ dan dari artikel yang berkenaan. Senarai penerbitan ini juga tidak dikhususkan kepada bidang sains klinikal sahaja malah ia merangkumi pelbagai bidang yang berkaitan dengan sains perubatan, sains pergigian, sains farmasi dan sebagainya. Saya ingin mengambil kesempatan ini untuk merakamkan ucapan penghargaan kepada semua staf di Pejabat Pelantar Penyelidikan di atas sokongan dan kerjasama yang telah diberikan dalam menjayakan aktiviti‐aktiviti dan laporan ini. Saya juga ingin merakamkan ucapan terima kasih kepada Profesor Dr. Syed Mohsin Syed Sahil Jamalullail selaku Dekan Penyelidikan Sains Kesihatan & Bioperubatan yang bekerjasama dalam pelbagai aktiviti Pelantar Penyelidikan Sains Klinikal, Professor Dr. Abdul Rahman Esa Pengurusi JEPeM, Timbalan‐timbalan Dekan Penyelidikan, Pusat Pengajian Sains Perubatan, Sains Pergigian, Sains Kesihatan, Sains Farmasi, Timbalan‐timbalan Pengarah, Institut Penyelidikan & Perubatan Molekul, Institut Perubatan dan Pergigian Termaju, Hospital Universiti Sains Malaysia dan ahli‐ahli JEPeM atas kerjasama dan sokongan yang diberikan. Sekian, wassalam. PROFESOR DR. NOR HAYATI OTHMAN Dekan Penyelidikan Sains Klinikal [email protected] | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | iv || LAPORAN TAHUNAN 2008 || 1. PENGENALAN Laporan Tahunan Pelantar Penyelidikan Sains Klinikal ini merangkumi keseluruhan aktiviti semasa Pelantar Penyelidikan Sains Klinikal dan aktiviti berkaitan penyelidikan yang dilaksanankan bagi tahun 2008 di Kampus Kesihatan ini. 2. OBJEKTIF DAN FUNGSI Peranan utama Pelantar Penyelidikan Sains Klinikal ini adalah untuk membantu serta menyokong Bahagian Penyelidikan & Inovasi terutamanya Pejabat Pengurusan & Kreativiti Penyelidikan (RCMO) dalam melaksanakan fungsinya di Kampus Kesihatan. Secara tidak langsung objektif spesifik Bahagian Penyelidikan & Inovasi digunapakai dan disesuaikan oleh Pelantar Penyelidikan Sains Klinikal, iaitu: i. Membudayakan penyelidikan pendidikan dikalangan pensyarah/penyelidik dengan meningkatkan pengetahuan dan kemahiran penyelidikan untuk kualiti penyelidikan yang bertaraf dunia. ii. Bertindak sebagai sumber maklumat dan pangkalan data bagi mengumpul, menyimpan dan menyebarkan maklumat yang berkaitan dengan penyelidikan semasa. iii. Mencari dan menyediakan peluang‐peluang geran/sumber kewangan penyelidikan dan menguruskannya dengan efisien dan seoptimum yang mungkin. iv. Membantu Bahagian Penyelidikan & Inovasi dalam mengambil langkah dan mengatur strategi untuk kemajuan kegiatan penyelidikan yang berkualiti setanding dengan perkembangan rancangan akademik universiti. v. Menyediakan kemudahan dan infrastruktur penyelidikan untuk memenuhi keperluan penyelidik dan pembangunan sumber manusia yang cemerlang untuk penyelidikan. 3. STRUKTUR PENGOPERASIAN Sistem pengoperasian Pelantar Penyelidikan Kampus Kesihatan terdiri dari dua pelantar iaitu: i) Pelantar Penyelidikan Sains Klinikal dan ii) Pelantar Penyelidikan Sains Kesihatan & Bioperubatan, yang diterajui oleh dua (2) Dekan Penyelidikan, tujuh (7) kakitangan tetap dan dua (2) kakitangan sambilan. Lokasi kedua‐dua pelantar ini juga berbeza iaitu Pelantar Penyelidikan Sains Klinikal berada di Aras 3, Bangunan Pusat Pengajian Sains Pergigian (PPSG) manakala Pelantar Penyelidikan Sains Kesihatan & Bioperubatan berada di Aras 1, Bangunan Pusat Pengajian Sains Kesihatan (PPSK). | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | 1 || LAPORAN TAHUNAN 2008 || 3.1 Untuk melaksanakan dan menjayakan objektif dan fungsi yang dinyatakan, pada 2 Januari 2008 Pelantar Penyelidikan di Kampus Kesihatan ini telah menerima seorang Penolong Pendaftar (N41) yang baru untuk memantapkan lagi perjalanan pentadbiran di Pejabat ini. Hasil dari penstrukturan semula gerak kerja, Pelantar Penyelidikan Kampus Kesihatan berfungsi seperti carta organisasi seperti di bawah: Rajah 1.0 : Struktur Organisasi Pelantar Penyelidikan, Kampus Kesihatan. | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | 2 || LAPORAN TAHUNAN 2008 || 3.2 Manakala Struktur Pengoperasian Pelantar Penyelidikan Sains Klinikal di Kampus Kesihatan ini telah menggunakan struktur pengoperasian seperti di bawah: DEKAN PENYELIDIKAN BAHAGIAN PENTADBIRAN BAHAGIAN PENYELIDIKAN J/KUASA ETIKA PENYELIDIKAN (Manusia) J/KUASA TEKNIKAL PENYELIDIKAN (Klinikal) 1. Memproses semua permohonan penyelidikan dari PTJ terlibat yang memerlukan kelulusan etika. 2. Memproses semua permohonan penyelidikan kajian klinikal dari syarikat luar/swasta yang memerlukan kelulusan etika. 3. Membantu memastikan kualiti kertas cadangan penyelidikan dan metodologi kajian adalah seperti saranan Jawatankuasa Etika & Penyelidikan (Manusia/Haiwan) USM. 4. Urusetia Mesyuarat Jawatankuasa Etika & Penyelidikan (Manusia dan Haiwan) USM yang diadakan setiap bulan. 5. Pemantauan dan pengemaskinian rekod‐rekod penyelidikan yang telah diluluskan oleh Jawatankuasa Etika & Penyelidikan (Manusia/Haiwan) USM. 6. Memajukan permohonan (Lulus Etika) yang memerlukan peruntukan kepada Jawatankuasa Teknikal Penyelidikan untuk dinilai. Menjalankan aktiviti‐aktiviti pentadbiran seperti: 1. Pengurusan Sistem Fail dan Rekod. 2. Pengurusan Kewangan dan Perolehan 3. Pengurusan Rekod Cuti Staf 4. Pengurusan Maklumat Peribadi Staf 5. Pengurusan Latihan Staf 6. Perjawatan 7. Pengurusan Aset 8. Mengemaskini Laman Web Pelantar Penyelidikan. 9. Pengurusetiaan dalam penganjuran bengkel/seminar. 10. Khidmat sokongan kepada bahagian lain di Pejabat Pelantar Penyelidikan Kampus Kesihatan. 1. Memproses semua permohonan penyelidikan dari PTJ terlibat yang memerlukan peruntukkan geran penyelidikan & telah mendapat kelulusan etika (manusia), jika berkaitan. 2. Menyemak dan menilai bajet geran penyelidikan yang dipohon oleh penyelidik agar berkualiti dan mengikut prosedur yang telah ditetapkan. 3. Urusetia kepada Mesyuarat Jawatankuasa Teknikal yang diadakan setiap bulan. 4. Pengemaskinian maklumat rekod‐ rekod dan pangkalan data penyelidikan dan jenis peruntukkan geran yang telah diluluskan oleh Jawatankuasa Teknikal USM. 5. Pemantauan laporan‐laporan kemajuan geran penyelidikan. 6. Memproses permohonan tambahan lain yang berkaitan geran‐geran penyelidikan. 7. Menjadi ‘one stop center’ untuk mendapatkan nasihat/pandangan mengenai geran‐geran penyelidikan yang sesuai dipohon serta lain‐lain maklumat mengenai geran penyelidikan. 8. Menyokong dan mengurus aktiviti‐ aktiviti yang dilaksanakan oleh Bahagian Penyelidikan & Inovasi dan juga oleh PTJ‐PTJ lain. Rajah 1.1 : Struktur Pengoperasian Pelantar Penyelidikan, Kampus Kesihatan. | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | 3 || LAPORAN TAHUNAN 2008 || 3.3 Jawatankuasa Teknikal Penyelidikan ‐ Sains Klinikal (JKTP) 3.3.1 Senarai Ahli Jawatankuasa Teknikal Penyelidikan Jadual 1.0: Senarai Ahli Jawatankuasa Teknikal Penyelidikan 2008 Bil Nama Jawatan 1. Prof. Dr. Nor Hayati Othman (Pengerusi) Dekan Penyelidikan Sains Klinikal 2. Prof. Dr. Syed Mohsin Syed Sahil Jamalullail Dekan Penyelidikan Sains Kesihatan & Bioperubatan 3. Prof. Rusli Nordin (sehingga September 2008) Timbalan Dekan Penyelidikan dan Siswazah, PPSG. 4. Prof. Dr. Zulkifli Ahmad (Mulai 1 Oktober 2008) Timbalan Dekan Penyelidikan dan Siswazah, PPSG. 5. Prof. Dr. Zalina Ismail Timbalan Dekan Penyelidikan dan Siswazah, PPSK. 6. Prof. Madya Mustafa Musa Timbalan Dekan Penyelidikan, PPSP. 7. Prof. Madya Dr. Rusli Ismail Timbalan Pengarah Penyelidikan, INFORMM. 8. Dr. Nik Min Raja Ahmad Timbalan Pengarah (Klinikal), HUSM. 9. Prof. Syed Hatim Noor Penyelaras Unit Biostatistik dan Metodologi, PPSP. 3.3.2 Mesyuarat Jawatankuasa Teknikal Penyelidikan 2008 Majoriti permohonan penyelidikan yang dibincangkan dalam mesyuarat ini terdiri dari geran USM Jangka Pendek manakala selebihnya adalah permohonan geran Universiti Penyelidikan. Jadual 1.1: Tarikh Mesyuarat Jawatankuasa Teknikal Tahun 2008 Bil Mesyuarat ke Tarikh Mesyuarat Kehadiran AJK Jumlah Permohonan Dibincangkan 1. 35 15 Jan 2008 4/8 21 2. 36 10 Mac 2008 3/8 11 3. 37 21 April 2008 4/8 11 4. 38 18 Mei 2008 5/8 09 5. 39 29 Jun 2008 4/8 08 6. 40 14 Julai 2008 4/8 09 7. 41 16 September 2008 5/8 16 8. 42 09 November 2008 4/8 10 JUMLAH PERMOHONAN | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | 95 4 || LAPORAN TAHUNAN 2008 || Jadual 1.2: Permohonan Geran Penyelidikan yang dinilai oleh Mesyuarat JKTP 2008 Bil Pusat Pengajian Jumlah Permohonan Peratus Permohonan 1. Pusat Pengajian Sains Perubatan 78 83.9% 2. Pusat Pengajian Sains Pergigian 09 9.6% 3. Pusat Pengajian Sains Kesihatan 06 6.5% 95 100% JUMLAH PERMOHONAN Sepanjang 2008, sebanyak 95 permohonan geran penyelidikan dibincangkan dalam mesyuarat seperti di atas. Majoriti permohonan adalah dari Pusat Pengajian Sains Perubatan (PPSP) yang melibat 83.9%. 3.4 Jawatankuasa Etika Penyelidikan (Manusia) – (JEPeM) Pelantar Penyelidikan Sains Klinikal telah mengambilalih tanggungjawab penuh jawatankuasa ini mulai bulan April 2008 dari Pusat Pengajian Sains Perubatan sebelum ini. Jawatankuasa ini kemudiannya diterajui oleh Pengerusi barunya iaitu Profesor Abd. Rahman Esa. Nama jawatankuasa ini juga telah ditukar dari Jawatankuasa Penyelidikan & Etika Manusia [JKEP], PPSP kepada Jawatankuasa Etika Penyelidikan (Manusia) [JEPeM], USM. Jawatankuasa Etika Penyelidikan Manusia (JEPeM) USM berfungsi untuk membincang, menilai dan meluluskan proposal penyelidikan yang melibatkan manusia sebagai subjek dalam sesuatu kajian. Penyelidik‐penyelidik dari dalam (staf atau pelajar USM) atau luar USM (bukan staf atau pelajar) yang membuat kajian di Universiti Sains Malaysia yang melibatkan manusia sebagai subjek kajian hendaklah memohon kelulusan etika manusia terlebih dahulu sebelum menjalankan kajian. Selain itu, jawatankuasa ini juga berfungsi untuk membincangkan permohonan kelulusan etika bagi para penyelidik yang memohon Geran Jangka Pendek, Geran Universiti Penyelidikan, Geran Science Fund dan lain‐lain geran. Jadual 1.3: Senarai Ahli Jawatankuasa Etika (JEPeM), (Sehingga Oktober 2008) Bil Nama Ahli Jawatankuasa JEPeM Bidang Kepakaran 1. Prof. Abd. Rahman Esa (Pengerusi) 2. Dato’ Hj. Wan Mohamed Yusoff 3. Dato’ Hj. Abdul Razak Salleh 4. Tuan Haji Ismail Hassan 5. Prof. Ahmad Sukari Halim Reconstructive Surgeon 6. Prof. Mohd Razali Salleh Psychiatrist 7. Prof. Jalaluddin Asraful Haq | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | Medical Education/ Community Medicine Mantan Setiausaha Kerajaan Kelantan Mewakili kepentingan masyarakat Mantan Guru Bahasa USM Clinical Microbiology 5 || LAPORAN TAHUNAN 2008 || 8. Prof. Rahmat Awang Pharmacologist 9. Prof. Saringat Haji Baie Pharmacologist 10. Dr. Zainul Ahmad Rajion Craniofacial Surgeon 11. Prof. Madya Dr. Ibrahim Lutfi 12. Prof. Quah Bang Seng Peadiatrician 13. Prof. Madya Siti Hawa Ali Social Scientist 14. Dr. Zaidun Kamari 15. Datin Dr. Hjh. Aesah@ Zaharah Hj. Awang 16. En. Halim Othman (Setiausaha) Radiologist Pengarah HUSM Wakil Kementerian Kesihatan Malaysia Ketua Pegawai Sains Kanan Jadual 1.4: Senarai Ahli Jawatankuasa Etika (JEPeM), (Bermula November 2008) Bil Nama Ahli Jawatankuasa JEPeM Bidang Kepakaran 1. Prof. Mohd Shukri Othman (Pengerusi) Obstetrik & Ginekologi 2. Dato’ Hj. Wan Mohamed Yusoff 3. Dato’ Hj. Abdul Razak Salleh 4. Tuan Haji Ismail Hassan 5. Prof. Ahmad Sukari Halim Reconstructive Surgeon 6. Prof. Mohd Razali Salleh Psychiatrist 7. Prof. Jalaluddin Asraful Haq 8. Prof. Rahmat Awang Pharmacologist 9. Prof. Saringat Haji Baie Pharmacologist 10. Dr. Zainul Ahmad Rajion Craniofacial Surgeon 11. Prof. Madya Dr. Ibrahim Lutfi 12. Prof. Quah Bang Seng 13. Prof. Madya Siti Hawa Ali 14. Dr. Zaidun Kamari 15. Dr. Mohamad Ismail 16. Pn. Mazlita Zainal Abidin (Setiausaha) Bekas Setiausaha Kerajaan Kelantan Mewakili kepentingan masyarakat Mantan Guru Bahasa USM Clinical Microbiology Radiologist Peadiatrician Social Scientist Pengarah HUSM Wakil Kementerian Kesihatan Malaysia Pegawai Sains | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | 6 || LAPORAN TAHUNAN 2008 || Jadual 1.5: Permohonan dinilai dalam Mesyuarat Jawatankuasa Etika Penyelidikan (Manusia) 2008 Mesyuarat JEPeM (Tarikh/Kehadiran) Bil Mesyuarat: 198 Tarikh: 08/01/08 Kehadiran: 12/16 hadir Bil Mesyuarat: 199 Tarikh: 06/02/08 Kehadiran: 9/16 hadir Bil Mesyuarat: 200 Tarikh: 05/03/08 Kehadiran: 9/16 hadir Bil Mesyuarat: 201 Tarikh: 09/04/08 Kehadiran: 10/16 hadir Bil Mesyuarat: 202 Tarikh: 15/05/08 Kehadiran: 11/16 hadir Bil Mesyuarat: 203 Tarikh: 04/06/08 Kehadiran: 12/16 hadir Bil Mesyuarat: 204 Tarikh: 16/07/08 Kehadiran: 7/16 hadir Bil Mesyuarat: 205 Tarikh: 27/08/08 Kehadiran: 8/16 hadir Bil Mesyuarat: 206 Tarikh: 29/10/08 Kehadiran: 14/16 hadir Bil Mesyuarat: 207 Tarikh: 26/11/08 Kehadiran: 12/16 hadir Bil Mesyuarat: 208 Tarikh: 24/12/08 Kehadiran: 9/16 hadir Kelulusan Etika Sahaja Geran Jangka Pendek Geran Universiti Penyelidikan Kajian Klinikal Geran Lain Jumlah 20 1 7 2 0 30 13 2 7 4 1 27 19 3 3 2 0 27 18 5 4 2 0 29 21 5 1 0 0 27 9 4 2 1 4 20 16 4 1 4 0 25 16 1 5 3 0 25 14 3 3 2 2 24 5 3 6 1 0 15 9 1 3 4 1 18 Jumlah 160 32 42 25 8 267 Berdasarkan Jadual 1 secara keseluruhannya, sebanyak 267 permohonan kelulusan etika telah diproses oleh Jawatankuasa Etika Penyelidikan (Manusia) USM di pejabat Pelantar Penyelidikan Klinikal pada tahun 2008. Kesemua permohonan ini termasuk permohonan kelulusan etika sahaja (kelulusan etika dan dissertasi pelajar pra‐siswazah dan pelajar siswazah), permohonan kelulusan etika menggunakan Geran Jangka Pendek USM, permohonan kelulusan etika menggunakan Geran Universiti Penyelidikan, permohonan kelulusan etika menggunakan geran‐geran lain dan permohonan kelulusan etika bagi kajian klinikal pembiayaan syarikat farmaseutikal. Untuk senarai perincian permohonan yang diproses oleh JEPeM, sila rujuk Lampiran 1 ‐ Permohonan dinilai dalam Mesyuarat Jawatankuasa Etika Penyelidikan (Manusia) 2008. | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | 7 || LAPORAN TAHUNAN 2008 || Jadual 1.6: Pecahan Permohonan Kelulusan Etika Mengikut Pusat Tanggungjawab (PTJ) Bilangan Mesyuarat [Tarikh Mesyuarat] Bilangan Permohonan PPSP PPSK PPSG INFORMM HUSM PTJ Lain 198 [08/01/08] 30 24 ‐ 2 1 ‐ 3 199 [06/02/08] 27 24 1 ‐ 1 ‐ 1 200 [09/04/08] 27 20 2 3 1 ‐ 1 201 [09/04/08] 29 21 4 1 ‐ ‐ 3 202 [15/05/08] 27 23 ‐ 2 ‐ ‐ 2 203 [04/06/08] 20 13 3 2 1 1 ‐ 204 [16/07/08] 25 21 ‐ ‐ ‐ 1 3 205 [27/08/08] 25 20 4 ‐ ‐ ‐ 1 206 [29/10/08] 24 15 4 1 ‐ ‐ 4 207 [26/11/08] 15 6 5 4 ‐ ‐ ‐ 208 [24/12/08] 18 15 1 ‐ 1 ‐ 1 JUMLAH 267 202 24 15 5 2 19 JUMLAH MENGIKUT PTJ 248 JUMLAH KESELURUHAN 19 267 Jadual 1.6 menunjukkan bilangan permohonan yang diterima oleh Jawatankuasa Etika Penyelidikan Manusia (JEPeM) pada tahun 2008 mengikut Pusat Tanggungjawab (PTJ) di Kampus Kesihatan dan juga PTJ seperti Kampus Induk sebanyak 10 permohonan dan Kampus Kejuruteraan pula sebanyak 9 permohonan. Pusat Pengajian Sains Perubatan (PPSP) mencatatkan bilangan permohonan tertinggi pada tahun 2008 iaitu sebanyak 202 permohonan dan diikuti oleh Pusat Pengajian Sains Kesihatan (PPSK) sebanyak 24 permohonan, manakala Pusat Pengajian Sains Pergigian PPSG sebanyak 15 permohonan, INFORMM sebanyak 5 permohonan dan HUSM sebanyak 2 permohonan sahaja menjadikan permohonan yang diterima berjumlah 267 permohonan secara keseluruhannya. Carta 1 : Jumlah Permohonan Kelulusan Etika Penyelidikan Klinikal Tahun 2008 30 Bilangan Permohonan 25 20 15 10 5 8 -0 is D 8 -0 ov N 8 -0 kt O 08 sgo O 8 l-0 Ju 08 nJu 8 -0 ei M 8 -0 pr A 8 -0 ar M 8 0 bFe 08 nJa 0 Carta 1 menunjukkan jumlah permohonan kelulusan etika yang diterima oleh Pelantar Penyelidikan Klinikal megikut bulan pada tahun 2008. | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | 8 || LAPORAN TAHUNAN 2008 || Carta 2 menunjukkan permohonan Carta 2: Permohonan Kelulusan Etika Penyelidikan Klinikal pada tahun 2008 mengikut kategori kelulusan etika penyelidikan klinikal yang diterima mengikut kategori. Majoriti 9% Kelulusan Etika Tanpa Geran 3% permohonan kelulusan etika adalah tanpa geran (60%) yang mana merupakan Kelulusan Menggunakan Geran Jangka Pendek USM 16% permohonan dissertasi pelajar siswazah. 60% 16% adalah permohonan menggunakan Geran Universiti Penyelidikan, Kelulusan Etika Menggunakan Geran Universiti Penyelidikan Kajian Klinikal Pembiayaan Pharmaceutical Company 12% 12% Kelulusan Etika Mengunakan Lain‐lain Geran mengunakan Geran Jangka Pendek USM. Pada 4 Julai 2007, hasil dari Mesyuarat JEPeM ke‐192 Minit 192.4 Perkara (6): Kaedah ‘Expedited Review’ telah dilaksanakan untuk mempercepatkan permohonan etika bagi kes‐kes yang tidak berisiko tinggi seperti kajian yang menggunakan borang soal selidik, menyemak folder pesakit, menyemak filem x‐ray pesakit dan sebagainya. Melalui kaedah ini hanya Pengerusi dan salah seorang AJK JEPeM diperlukan untuk menapis/membuat saringan dengan dihadiri oleh penyelidik bagi membentang ‘proposal’ untuk mendapat kelulusan etika berkenaan. Kekerapan ‘evpedited review’ ini dibuat setiap dua kali sebulan atau mengikut kesesuaian. Jadual 1.7: Bilangan Kertas Cadangan Penyelidikan dibentang dalam Mesyuarat Expedited Review Bil 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. Tarikh Expedited Review 08 Januari 2008 22 Januari 2008 31 Januari 2008 20 Februari 2008 27 Februari 2008 13 Mac 2008 27 Mac 2008 22 April 2008 29 April 2008 20 Mei 2008 25 Jun 2008 03 Julai 2008 31 Julai 2008 13 Ogos 2008 15 Oktober 2008 6 November 2008 17 Disember 2008 JUMLAH Geran Penyelidikan 05 02 01 05 06 04 04 03 05 03 02 02 04 03 03 02 02 56 Dissertasi Pelajar Siswazah 03 04 04 03 01 03 03 06 02 06 04 05 03 04 05 01 02 59 Jumlah Permohonan Dibincangkan 08 06 05 08 07 07 07 09 07 09 06 07 07 07 08 03 04 115 | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | 9 || LAPORAN TAHUNAN 2008 || 4. GERAN PENYELIDIKAN Geran penyelidikan yang melibatkan pelbagai bidang telah pun ditawarkan kepada staf USM. Peruntukan geran penyelidikan diperolehi mengikut jenis geran adalah seperti berikut: JUMLAH PERUNTUKAN GERAN PENYELIDIKAN USM BAGI TAHUN 2008 RM 643,152.00 RM 1,859,307.00 RM 2,222,187.00 RM 110,000.00 RM 8,600,476.00 JANGKA PENDEK UNIVERSITI PENYELIDIKAN INSENTIF SCIENCE FUND GERAN LUAR 4.1 GERAN JANGKA PENDEK USM Jumlah Geran Jangka Pendek Diluluskan Mengikut Pusat Pengajian 2008 Nilai Geran(RM) 1,159,112.00 1,200,000.00 1,000,000.00 800,000.00 600,000.00 203,139.00 400,000.00 141,433.00 31,308.00 200,000.00 Sains Perubatan Sains Pergigian Sains Kesihatan Pengajian Seni Pusat Pengajian Jadual 1.8: Bilangan Geran USM Jangka Pendek Diluluskan Mengikut Pusat Pengajian 2008 Bil Pusat Pengajian Jumlah Geran Peratus Nilai Geran (RM) 1. Sains Perubatan 50 76% 1,159,112.00 2. Sains Pergigian 08 13% 203,139,.00 3. Sains Kesihatan 05 09% 141,433.00 4. Pengajian Seni 01 02% 31,308.00 JUMLAH 64 100% 1,534,992.00 Untuk senarai perincian geran USM Jangka Pendek, sila rujuk Lampiran 2 ‐ Senarai Pemegang Geran Jangka Pendek USM 2008. | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | 10 || LAPORAN TAHUNAN 2008 || 4.2 GERAN UNIVERSITI PENYELIDIKAN Geran Universiti Penyelidikan Aktif bagi Tahun 2008 mengikut Pusat Pengajian 105,000.00 sia an an u 193,992.00 ru sa n 1,128,782.00 Ilm ng u u Ke m ig i rg 386,455.00 Te Fa ru si ha rm rm ba ta aj ta as n u n i in s Pe an Pe 1,275,700.00 in s & Sa ub . er 4,062,417.00 Sa in s Pe Sa in s t. P In s 1,448,130.00 Ke Pe rg ig ia n Sa - 50 0, 0 0 0.0 0 1,0 00 ,00 0.0 0 1,5 0 0,0 00 .00 2,0 0 2,5 0 0,0 00 .00 0,0 00 .00 3,0 00 ,00 0.0 0 3,5 00 ,00 0.0 0 4,0 00 ,00 0.0 0 4,5 0 0,0 00 .00 Nilai Geran (RM) Untuk senarai perincian Pemegang Geran Universiti Penyelidikan, sila rujuk Lampiran 3 ‐ Senarai Pemegang Geran Penyelidikan Universiti. 4.3 GERAN SCIENCE FUND Jadual 1.9: Geran Aktif Science Fund 2008 Bil Pusat Pengajian Jumlah Geran Nilai Geran (RM) 1. Sains Perubatan 09 RM 1,136,626.00 2. Sains Pergigian 05 RM 647,649.00 3. Institut Perubatan & Pergigian Termaju 01 RM 247,916.00 4. Sains Kesihatan 01 RM 189,996.00 16 RM 2,222,187.00 JUMLAH Jadual 2.0: Jumlah Permohonan mengikut Kategori Bidang Kajian (Science Fund) Bil Bidang Kajian Jumlah Permohonan 1. Bioteknologi 8 2. Industri 4 3. Perkhidmatan Sains & Teknologi 2 4. Pertanian 1 5. ICT 1 JUMLAH 16 | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | 11 || LAPORAN TAHUNAN 2008 || 4.4 GERAN INSENTIF Jadual 2.1: Geran Insentif Diluluskan 2008 Bil Pusat Pengajian Jumlah Geran Nilai Geran (RM) 1. Sains Kesihatan 19 RM 71,000.00 2. Sains Farmasi 05 RM 13,000.00 3. INFORMM 03 RM 15,000.00 4. Sains Pergigian 02 RM 10,000.00 5. Institut Perubatan & Pergigian Termaju 01 RM 1,000.00 30 RM 110,000.00 JUMLAH 4.5 KAJIAN KLINIKAL KONTRAK (Contract Clinical Trials) Jadual 2.2: Senarai Geran Kajian Klinikal Kontrak Tahun 2008 Bil 1. 2. 3. 4. Nama Penyelidik dan Tajuk Penyelidikan Dr. Che’ Wan Aminud‐din B Hashim M/273FO/23: A randomised, 4‐week, placcebo‐ controlled, double‐blind, 6 arm parallel group, dose‐ finding clinical trial, to assess the efficacy, safety and pharmacokinetics of three different doses of formoterol (6, 12 &18 µg, aclidinium bromide 200µg monotherapy and formoterol 12 µg monotherapy all administered once daily by inhalation via Almirall inhaler in patients with stable moderate to severe Chronic Obstructive Pulmonary Disease. Dr. Che’ Wan Aminud‐din B Hashim D5890L00027: Symbicort Maintenance and Reliever Therapy, Experience in Real Life Setting in Malaysia‐ ‘Smarter’ Study. Dr. Juwita Shaaban No. I.D: CVAA489 ARU01: Observational study to evaluate safety and effectiveness of the free combination of and 80mg/160mg valsartanamlodipine 5mg/10mg in the treatment of hypertension. Prof. Madya Rusli Ismail No I.D: INFOPHARMA 001/07: A Comparative Bioequivalence Study of Generic Pharmaniaga Doxycycline Capsule and the Proprietary Vibramycin Tablet (100mg of doxycycline). | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | Penaja / Nilai Tajaan Tempoh Mula/Tamat Kontrak Laboratorios Almiral, S.A (RM 36,000) May 2008 (12 Bulan) Astra Zeneca Sdn Bhd (RM 12,000) May 2008 (3 Bulan) NOVARTIS May 2008 (12 Bulan) Pharmaniaga Research Centre Sdn Bhd (RM 84,998) May 2008 (12 Bulan) 12 || LAPORAN TAHUNAN 2008 || Prof. Madya Saiful Bahari Ismail MK‐0859 Protocol 019‐00: A 76‐week, Worldwide, Multicenter, Double‐blind, Randomised, Placebo‐ controlled Study to Assess the Tolerability and Efficacy of Anacetrapib When added to ongoing Therapy With a Statin in patients with Hypercholesterolaemia or mixed Hyperlipidaemia. Prof. Dato’ Dr. Mafauzy Mohamed No. ID: 28431754‐DIA‐2001: A Randomized, Double‐ Blind, Placebo‐Controlled, Double‐Dummy, Parallel‐ Group, Multicenter, Dose‐Ranging Study in Subjects With Type 2 Diabetes Mellitus to Evaluate the Efficacy, Safety, and Tolerability of Orally‐Administered SGLT2 Inhibitor JNJ‐28431754 With Sitagliptin as a Reference Arm. Prof. Madya Dr. Shaiful Bahari Ismail No ID: EFC10518: A randomized, double blind, placebo controlled study evaluating the glycaemic effect of rimonabant added to metformin in patients with type 2 diabetes insufficiently controlled with metformin monotherapy – TOCCATA. Prof. Dato’ Dr. Mafauzy Mohamed No ID: EFC10518: A randomized, double‐blind, placebo‐ controlled parallel group efficacy and safety study of BI1356 (5mg administered orally once daily) over 24 weeks,in drug naive or previously treated (6 weeks washout) type 2 diabetic patients with insufficient glycaemic control. Dr. Amran Ahmed Shokri A Phase III Randomized, Double Blind, Parallel‐Group Study of the Efficacy and Safety of Oral Dabigatran Etixilate (150 mg bid) compared to Warfarin (INR 2.0‐ 3.0) for 6 Month Treatment of Acute Symptomatic VenousThromboembolism Following Initial Treatment for At Least 5 days with a Parenteral Anticoagulant Approved for this Indication. Merck & Co., Inc. (RM 80,200) Februari 2008 (24 Bulan) Janssen Cilag (RM 23,000) Mac 2008 (03 Bulan) Sanofi Aventis (RM 23,325) Mac 2008 (18 Bulan) Boehringer Ingelheim (RM 100,100) Mac 2008 (12 Bulan) Boehringer Ingelheim 38 Bulan (hingga Feb 2011) 10. Prof. Dr. Zurkurnai Yusof Participation in SeQuent Please International Registry. B. Braun Medical Supplies Sdn. Bhd (3 Bulan) 11. Prof. Dato’ Dr. Mafauzy Mohamed A2581162: An Outcome Research on the Impact of a Disease Management Program (Coach) on the Attainment of Better Cardiovascular Risk Control in Dyslipidemic Patients at Primary Care Centers (Disseminate). Pfizer (RM 12,478.50) (24 minggu) 5. 6. 7. 8. 9. | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | 13 || LAPORAN TAHUNAN 2008 || 12. 13. 14. 15. 16. 17. 18. Prof. Dato’ Dr. Wan Mohamad Wan Bebakar Protocol ID: EFC10743/GETGOAL_F1: A Randomized, Double‐Blind, Placebo‐Controlled, Parallel‐Group, Multicenter, 24‐Week Study Followed by an Extension Assessing The Efficacy and Safety of AVE0010 in two Titration Regimens on top of Metformin in Patients With Type 2 Diabetes Not Adequately Controlled with Metformin. Prof. Abdul Aziz Baba Protocol ID: EFC10528/ FLAMENCO: A Multicenter, Double Blind, Placebo Controlled, Randomized Study of TroVax ® vs. Placebo in the First Line Treatment of Patients with Metastatic Colorectal Cancer Receiving Standard of Care. Prof. Dato’ Dr. Mafauzy Mohamed Protocol ID: MK‐0941 Protocol 007: A Phase IIb/III, Multicenter, Randomized, Double‐Blind, Placebo‐ Controlled Dose‐Range Finding Clinical Trial of MK‐ 0941 in Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Insulin. Prof. Dato’ Dr. Mafauzy Mohamed Protocol ID: PHX1149‐PROT301: A Phase 3, Randomized, Double‐Blind, Placebo‐Controlled, Multi‐ Center Study to Evaluate Safety and Efficacy of PHX1149T as Monotheraphy in Subjects With Type 2 Diabetes Mellitus. Prof. Madya Dr. Mohd Jamil Yaakob Protocol No: R076477SCH4016: PILAR: Pharmacoepidemiologic International Longitudinal Antipsychotic Registery. Prof. Madya Dr. Mohd Jamil Yaakob CATIE‐Like Study: A Multi‐Center, Retrospective, Comparative Study to Investigate Drug Utilization Patterns And Treatment Period Associated With Atypical Antipsychotics Treatment in Schizophrenia and Schizoaffective Disorders: Aripiprazole, Olanzapine, Quetiapine and Risperidone. Prof. Dato’ Dr. Mafauzy Mohamed BI1218.40: A 78 Week, Open Label Extension To Trials Assessing the safety and Efficacy of BI 1356 (5mg) as monotherapy or in combination with other antidiabetic medications in type 2 diabetic patients. | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | Sanofi Aventis (RM43,600) (08 Bulan) Sanofi Aventis (RM 133,900) (4 tahun) Merck & Co. Inc. (RM103,160) Julai 2008 (12 Bulan) Phenomix Corporation (RM34,980) Julai 2008 ( 06 Bulan) Janssen‐Cilag (RM 25,050) September 2008 (12 Bulan) Janssen‐Cilag (RM6,200) September 2008 (06 Bulan) Boehringer Ingelheim September 2008 (24 Bulan) 14 || LAPORAN TAHUNAN 2008 || 19. 20. 21. 22. 23. 24. 25. Prof. Madya Zurkurnai Yusof MK‐0653A Protocol 134: A Randomized, Double‐Blind, Active‐Controlled, Multicenter Study of Patients with Primary Hypercholesterolemia and High Merck & Co., Inc. Cardiovascular Risk and not Adequately Controlled (RM 66, 000) with Atorvastatin 20 mg: A Comparison of Switching to a Combination Tablet Ezetimibe/Simvastatin (10mg/40mg) versus Doubling the Baseline Dose to Atorvastatin 40 mg. Prof. Dato’ Wan Mohamed Wan Bebakar No. Protokol: MK0736 Protocol 007: A Worldwide, Multicenter, Double‐Blind, Randomized, placebo‐ Controlled, Dose Ranging Study to Evaluate the Merck & Co., Inc. efficacy, safety and Tolerability of MK‐0736 When (RM 139,000.00) Added to Ongoing Therapy With Angiotensin‐ Converting Enzyme (ACE) Inhibitor or Angiotensin Receptor Blocker (ARB) in Patients With Diabetes and Hypertension. Prof. Madya Dr. Zurkurnai Yusof CV185036: A phase 3 randomized, Double‐blind, Parallel‐group, Multi‐center Study of the safety and Bristol‐Myers Efficacy of Apixaban for Prophylaxis of Venous Squibb Thromboembolism in Acutely III Medical Subjects (RM 141,600) During and Following Hospitalization. Prof. Madya Dr. Shaiful Bahari Ismail Biotropic Malaysia Study on the use of Tongkat Ali as Herbal Supplements Bhd for the Improvement of the Quality of Life & Sexual (RM 276,625) Wellbeing in Males. Prof. Madya Dr. Zurkurnai Yusof ENGAGE AF – TIMI 48: A Phase 3, Randomized, Double‐Blind, Double‐Dummy, Parallel Group, Daiichi Multicenter, Multi‐National Study For Evaluation of Sankyo Pharma Efficacy and Safety of DU‐176B versus warfarin in Development subjetcs with atrial fibrillation – Effective (RM 135, 900) aNticoaGulation with Factor xA next Generation in Atrial Fibrillation. Prof. Madya Dr. Zurkurnai Yusof RIVAROXACS3001: A Randomized, Double‐ Blind, Bayer Placebo‐ Controlled, Event‐ Driven Multicenter Study Health Care to Evaluate the Efficacy and Safety of Rivaroxaban in (RM 135, 900) Subjects With a Recent Acute Coronary Syndrome. Wyeth Research Dr. Mohd Suhaimi Ab Wahab Division of Wyeth A Retrospective Study to Assess the Clinical Burden of Pharmaceuticals Community‐Acquired Pneumonia (CAP) and Invasive Inc. Philedelphia Pneumococcal Disease (IPD). (RM 164,024.46) | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | Julai 2008 (12 Bulan) November 2008 (8 Bulan) Disember 2008 (12 Bulan) Jan 2009 (12 Bulan) Jan 2009 (20 Bulan) Jan 2009 (36 Bulan) Jan 2009 (12 Bulan) 15 || LAPORAN TAHUNAN 2008 || 5. AKTIVITI PELANTAR PENYELIDIKAN SAINS KLINIKAL, KAMPUS KESIHATAN TAHUN 2008 Berdasarkan perancangan penyelidikan tahun 2008, beberapa aktiviti telah dilaksanakan hasil dari pembentangan halatuju penyelidikan pada 07 Januari 2008 untuk Pelantar Penyelidikan, Kampus Kesihatan. Jadual 2.4: Senarai Aktiviti Pelantar Penyelidikan Klinikal Tahun 2008 Bil Aktiviti Tarikh Tempat 1. Mesyuarat Ke‐1 Bengkel Scentific Writing 2008 Mesyuarat ini diadakan kali pertama bagi membincangkan mengenai penganjuran Bengkel Scientific Writing yang diadakan setiap tahun. Untuk tahun 2008, pihak Jabatan Perubatan Masyarakat dan Pelantar Penyelidikan Sains Klinikal telah diberikan kepercayaan untuk proses penganjuran dan pengurusetiaan bengkel tersebut. 16/01/2008 Bilik Mesyuarat PPK 2. Mesyuarat Dalaman Staf Pelantar Penyelidikan Klinikal bersama Pelantar Bioperubatan Mesyuarat ini diadakan untuk perbincangan rutin dan perancangan aktiviti yang akan dilaksanakan bagi tahun 2008. 17/01/2008 Bilik Mesyuarat PPK 3. Mesyuarat bersama Jabatan Pembangunan ‐ Pembinaan Pejabat Baru Pelantar Mesyuarat ini diadakan untuk membincangkan mengenai pelan susun atur pejabat baru pelantar yang akan dibina di lokasi baru iaitu bersebelahan perpustakaan hamdan tahir. 27/01/2008 Bilik Mesyuarat PPK 4. Mesyuarat Penyelidikan dan Pembangunan Madu Lebah Tualang: USM –FAMA Hasil dari mesyuarat ini, pihak FAMA telah bersetuju untuk menyumbang sebanyak 1610kg madu lebah tualang untuk tujuan penyelidikan. 05/02/2008 Bilik Persidangan, PPSG 03/03/2008 Bilik Mesyuarat PPK 11/03/2008 Bilik Persidangan, PPSG 16/03/2008 Bilik Mesyuarat PPK 5. 6. 7. Mesyuarat Pengurusan Bajet Geran RU Perbincangan Projek ‘Sustainable Health’ Perbincangan ini diadakan dengan kerjasama pihak penganjur luar iaitu UNU – IIGH (United Nations University – International Institute of Global Health) dan Regional Centre of Experties on Education for Sustainable Development yang akan diadakan pada Mei 2008. Mesyuarat Pembinaan Blok Klinikal ‐ Makmal Pasca Siswazah dan Pejabat Pelantar Penyelidikan, RMK9 Hasil mesyuarat ini blok klinikal yang dicadangkan untuk pembangunan berjalan dengan lancar dan akan diteruskan ke peringkat lukisan pelan. | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | 16 || LAPORAN TAHUNAN 2008 || Bil 8. 9. 10. 11. 12. 13. 14. Aktiviti Perjumpaan bersama Biro Pengawalan Farmaseutikal Kebangsaan Perjumpaan ini merupakan aktiviti Dekan Penyelidikan Sains Klinikal sebagai satu langkah untuk menjalinkan hubungan bersama dengan agensi kerajaan bagi memudahkan urusan pentadbiran penyelidikan. Telesidang bersama Naib Canselor – Pembentangan Projek ‘Sustainable Health’ Telesidang ini diadakan sebagai susulan dari perbincangan yang telah diadakan pada bulan Mac yang lepas. Mesyuarat bersama Jabatan Perkhidmatan Veterinar Perjumpaan ini merupakan aktiviti Dekan Penyelidikan Sains Klinikal sebagai satu langkah untuk menjalinkan hubungan bersama dengan agensi kerajaan bagi memudahkan urusan pentadbiran penyelidikan. Mesyuarat bersama Pengarah Baru FAMA Negeri Kedah Mesyuarat ini diadakan bagi memberi pengenalan kepada pengarah baru FAMA Negeri Kedah iaitu En. W. Abdullah W. Chik dengan disertai beberapa pegawai FAMA lain mengenai jalinan kerjasama projek kluster madu USM – FAMA. Pameran Madu Asli Lebah Tualang sempena Sustainable Health Thematic Workshop Hasil dari pameran ini, peserta bengkel yang terdiri dari luar negara telah diberikan maklumat terbaru mengenai khasiat madu tempatan dan dengan kerjasama FAMA, sebanyak 320 botol Madu Lebah Tualang berjaya dijual sepanjang pameran diadakan. Mesyuarat bersama Jabatan Pembangunan – Pembinaan Pejabat Baru Pelantar Mesyuarat ini diadakan susulan dari mesyuarat lepas. Projek pembinaan ini kini dalam proses penghasilan sebut harga dan lawatan tapak dijadualkan pada Julai 2008. Taklimat Akreditasi Jabatan STANDARD MALAYSIA dengan kerjasama Pelantar Penyelidikan Kampus Kesihatan. Taklimat akreditasi ini telah berjaya mendedahkan kepada peserta tentang jenis‐jenis akreditasi yang diberikan oleh Jabatan Standard Malaysia. Maklumat ini penting kepada penyelidik‐penyelidik dan juga makmal‐makmal yang menjalankan kajian tertentu untuk memastikan kajian dilakukan mencapai tahap standard yang ditetapkan. | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | Tarikh Tempat 29/04/2008 Kuala Lumpur 15/05/2008 PPKT 20/05/2008 Bilik Mesyuarat PPK 20/05/2008 Bilik Mesyuarat PPK 21/05/2008 BPU, Pej. Pengarah Kampus 25/05/2008 Bilik Mesyuarat PPK 26/05/2008 DK 8, PPSP 17 || LAPORAN TAHUNAN 2008 || Bil 15. 16. 17. 18. 19. 20. 21. Aktiviti 4h National Workshop on Scentific Writing 2008 Bengkel 2 hari ini telah dianjurkan dengan jayanya dengan penyertaan peserta yang menggalakkan terdiri dari pelbagai jabatan dan agensi luar dan dalam USM seramai 98 orang. Mesyuarat bersama UKP – Keperluan Makmal Pasca Siswazah dan Pejabat Pelantar Penyelidikan, RMK9 Mesyuarat ini diadakan bersama ketua jurutera UKP iaitu En. Wan Nasir bagi membincangkan mengenai keperluan‐keperluan makmal pasca siswazah, blok klinikal dibawah Projek RMK9. Mesyuarat Bangunan Blok Klinikal – Projek RM9 Hasil mesyuarat ini blok klinikal yang dicadangkan untuk pembangunan kini di peringkat akhir perbincangan mengenai keperluan yang diperlukan di dalam makmal pasca siswazah, blok klinikal. Perbincangan berkaitan Isu‐isu Pengajian Siswazah Perbincangan ini dihadiri oleh Timbalan‐timbalan Dekan (Penyelidikan) pusat pengajian di Kampus Kesihatan dan dipengerusikan oleh Pemangku Dekan Penyelidikan Sains Klinikal iaitu Prof. Ahmad Sukari Halim. Mesyuarat Pegawai‐pegawai Sains Bahagian Penyelidikan di Kampus Kesihatan Mesyuarat ini diadakan untuk membincangkan langkah‐langkah penambahbaikkan mengenai pengurusan permohonan penyelidikan dan memaklumkan kepada bahagian yang terlibat mengenai Sistem Permohonan Geran Secara Online (eR&I) yang baru diperkenalkan oleh RCMO. Mesyuarat Penyelidikan dan Pembangunan Madu Lebah Tualang: USM – FAMA Hasil mesyuarat ini telah berjaya membuat keputusan untuk mengadakan satu persidangan madu peringkat antarabangsa yang dijangka akan diadakan pada penghujung 2009. Seminar Transdisiplinari Seminar ini telah berjaya menarik ramai penyelidik dari seluruh kampus USM iaitu Kampus Kesihatan, Kampus Induk dan Kampus Kejuruteraan. Seramai 30 orang penyelidik telah membentangkan cadangan projek mereka dan hasil seminar ini telah berjaya mengumpulkan pakar‐ pakar dari pelabagai bidang untuk berkongsi idea dalam menjalankan kajian dan mencipta sesuatu alat yang boleh dimanfaatkan dalam bidang perubatan. Seminar sebegini akan diadakan dengan lebih kerap pada tahun hadapan atas permintaan mereka yang hadir. | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | Tarikh Tempat 21‐ 23/07/2008 DK 8, PPSP 03/08/2008 Bilik Mesyuarat UKP 25/08/2008 Bilik Mesyuarat Jab. Pembangunan 14/10/2008 Bilik Mesyuarat PPK 13/10/2008 Bilik Mesyuarat PPK 14/12/2008 Bilik Mesyuarat FAMA Negeri Kelantan 16/12/2008 DK 8, PPSP. 18 || LAPORAN TAHUNAN 2008 || 6. OUTPUT PENYELIDIKAN Jadual 2.4: Senarai Output Mengikut Pusat Pengajian bagi Tahun 2008 Jurnal Pusat Pengajian Persidangan Sumber Manusia Anugerah A’bangsa K’saan A’bangsa K’saan M.Sc Ph.D Sains Perubatan 21 22 16 40 11 01 08 Sains Pergigian 05 10 04 06 06 ‐ 01 Sains Kesihatan ‐ ‐ ‐ 03 ‐ ‐ ‐ 26 32 20 49 17 01 09 JUMLAH Output penyelidikan di atas majoriti diperolehi dari Laporan kemajuan dan laporan akhir Geran USM Jangka Pendek yang dihantar ke pejabat ini, manakala selebihnya diperolehi dari laporan Ahkir Geran IRPA. Untuk senarai perincian output penyelidikan berkenaan, sila rujuk Lampiran 4 ‐ Output Penyelidikan 2008. 7. RUMUSAN Berikut adalah jadual rumusan ringkas fakta dan nombor mengenai Penyelidikan Sains Klinikal bagi tahun 2008. Jadual 2.5: Senarai Rumusan Fakta dan Nombor Mengenai Aktiviti Pelantar Penyelidikan Sains Klinikal 2008 Bil Perkara Jumlah Permohonan Diproses Bilangan Nilai Geran (RM) 1. Mesyuarat JK Teknikal Peyelidikan (Klinikal) 95 ‐ ‐ 2. Mesyuarat JK Etika Penyelidikan (Manusia) 267 ‐ ‐ 3. Expedited Review JEPeM 119 ‐ ‐ 4. Jumlah Keseluruhan Dana Penyelidikan ‐ ‐ 13,435,122.00 5. Geran Jangka Pendek USM ‐ 64 1,534,992.00 6. Geran Aktif Universiti Penyelidikan (RU) ‐ 58 8,600,476.00 7. Geran Aktif Science Fund ‐ 16 2,222,187.00 8. Geran Insentif Diluluskan ‐ 30 110,000.00 9. Kajian Klinikal Kontrak (Syarikat Farmaseutikal) ‐ 25 1,778,040.96 10. Geran Luar ‐ ‐ 11. Bilangan Pelajar Sarjana (MSc) ‐ (Aktif) ‐ 17 ‐ 12. Bilangan Pelajar Sarjana (PhD) ‐ (Aktif) ‐ 01 ‐ 13. Bilangan Pelajar Sarjana Perubatan – (Aktif) ‐ 97 ‐ 14. Jurnal Antarabangsa ‐ 26 ‐ 15. Jurnal Kebangsaan ‐ 32 ‐ 16. Persidangan Antarabangsa ‐ 20 ‐ 17. Persidangan Kebangsaan ‐ 49 ‐ 18. Anugerah Diperolehi ‐ 09 ‐ | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | 643,152.00 19 || LAPORAN TAHUNAN 2008 || LAMPIRAN | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | 1 || LAPORAN TAHUNAN 2008 || LAMPIRAN 1 SENARAI PERMOHONAN DINILAI DALAM MESYUARAT JAWATANKUASA ETIKA PENYELIDIKAN (MANUSIA) ‐ JEPeM TAHUN 2008 | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | 2 || LAPORAN TAHUNAN 2008 || Mesyuarat ke 198 (08 Januari 2008) Bil Nama Penyelidik Tajuk Kategori Dr. Wan Nazirah Wan Yusuf The Effects of Madu ‐ Lebah Tualang on Asymptomatic HIV Patients. Geran Universiti Penyelidikan 2. Dr. Mukhtar Alam Ansari Choline compound quantification in determining aggresiveness of malignant breast disease using proton MR spectroscopy. Geran Universiti Penyelidikan 3. Prof. Madya Foong Kin Health survey of restaurant workers in Penang. Kelulusan Etika Sahaja 4. Prof. Dr. Sukari Halim A study on the microbiological and angiogenic properties of burn injuries treated with Tualang Honey versus Silver Based Dressings Geran Universiti Penyelidikan 5. Prof. Madya Dr. Hasnan Jaafar Attitude of Malaysian parents and health care professionals to the perinatal autopsy Kelulusan Etika Sahaja 6. Prof. Madya Kamaliah Mohd Daud Effects of adjuvant honey therapy on disease activity, lymphocyte function and lymphocyte subsets in patients with systemic lupus erythematosus(SLE). Geran Universiti Penyelidikan 7. Dr. Rajesh Kumar a/l Muniandy Dexmedetomidine Attenuates Sympathoadrenal Responces To Tracheal Intubation And Reduces The Need For Propofol. Kelulusan Etika Sahaja 8. Prof. Dr. Rahmah Nordin Molecular profiling of Toxoplasma gondii towards recombinant antigen and DNA‐based diagnostics for toxoplasmosis Geran Universiti Penyelidikan 9. Prof. Madya Dr. Gurjeet Kaur Analysis of germline mutatin spectra and abnormal protein Expression profile of DNA mismatch repair genes in clinically Diagnosed HNPCC patients in Malaysia‐ A multicentric study. Geran Universiti Penyelidikan 10. Dr. Marini Ramli Detection of Iron Defeciency Anaemia by Retic Haemoglobin (RET‐He) in hemodialysis patients on eryth ropoitein (EPO). Geran Jangka Pendek 11. Prof. Madya Dr. Nik Hazlina Nik Hussain The effects of Tualang Honey on Peri‐Menopausal Women Geran Universiti Penyelidikan 12. Dr. B. Vicknasingam Human and Animal Behavioural Studies of Mitragyna. Kelulusan Etika Sahaja 13. Dr. Che' Wan Aminud‐din Hashim A randomised, 4‐week, placcebo‐controlled, double‐blind, 6 arm parallel group, dose‐finding clinical trial, to assess the efficacy, safety and pharmacokinetics of three different doses of formoterol (6, 12 &18 µg, aclidinium bromide 200µg monotherapy and formoterol 12 µg monotherapy all administered once daily by inhalation via Almirall inhaler in patients with stable moderate to severe Chronic Obstructive Pulmonary Disease. Kajian Klinikal 14. Dr. Che' Wan Aminud‐din Hashim Symbicort Maintenance and Reliever Therapy, Experience in Real Life Setting in Malaysia‐ ‘Smarter’ Study. Kajian Klinikal 15. Dr. Hoh Boon Peng A Genome‐wide tudy of the Sporadic Colorectal Carcinomas(CRC) among Malaysian Geran Jangka Pendek 16. Dr. Wan Zaidah Abdullah A Pilot Study on Frequencues of Factor V Leiden Mutation and Prothrombin Gene Mutation among Healthy Indians Kelulusan Etika Sahaja 17. Dr. Wan Zaidah Abdullah Coagulation Factor XIII and Other Haemostatic Markers in Patients with Intra‐Cranial Surgery Geran Jangka Pendek 18. Dr. Tee Meng Hun N‐Terminal Pro B‐type Natriuretic Peptide Leel in Hypertensive Patients with Diastolic Dysfunction in HUSM. Geran Jangka Pendek 19. Dr. Shabbir Ahmad Sheikh A Study to Investigate the Effect of Hormone Replacement Therapy (HRT) on Platelet Activation Markers as Determined by Flow Cytometry in Healthy Post‐Menopausal Women. 20. Dr. Sami Mohammed Ali Al‐Ashwal MRI Study of CSF Dynamics at the Cerebral Aqueduct and Third Ventricle among Adult Malay Patient Who Have Normal Brain MRI in Hospital USM. 21. Dr. Haryati Hamzah Glycemic Control in Insulin Treated Type 2 Diabetes Patients Attending Diabetic Centre HUSM. 22. Dr. Murniyati Abd Wahid Quality of Life of Schizophrenic Patients in Hospital Universiti Sains Malaysia 23. Dr. Zainul Ahmad Rajion Dental Cast and Cephalometric Analysis of Unilateral and Bilateral Cleft Lip and Palate Using MorphoStudio. Geran Jangka Pendek 24. Dr. Rozita Hassan The Characteristics of Craniofacial and Dental Arch Morphology in Transfusion‐Dependent Thalassaemia Patients. Geran Jangka Pendek 25. Dr. Gam Lay Harn Study of the Protein Profile of Colon Cancer Cells. Geran Universiti Penyelidikan 26. Dr. Suhaimi Hussain Validation of Bahasa Melayu Version of the Diabetes Quality of Life Questionnaire (DQOL) and the Summary of Diabetes Self Care Activities Questionnaire (SDSCA). Kelulusan Etika Sahaja 27. Dr. Suhaimi Hussain Evaluation of Congenital Hypothyroid Screening Program. Geran Jangka Pendek 28. Dr. Nor Azwany Yaacob Risk Perception on Food Borne Diseases among Community in Kota Bharu, Kelantan Geran Jangka Pendek 29. Prof. Madya Dr. Hasanah Che Ismail Psychological Well Being among Breast Cancer Patient on Chemotherapy in Oncology Day Care Unit. Kelulusan Etika Sahaja 30. Dr. Noorizan Abdul Majid Overweight and Obesity Among Children in Kota Bharu, Kelantan: Prevalence and Cardiovascular Risk Factors. Kelulusan Etika (Pelajar Sarjana Perubatan) Kelulusan Etika (Pelajar Sarjana Perubatan) Kelulusan Etika (Pelajar Sarjana Perubatan) Kelulusan Etika (Pelajar Sarjana Perubatan) Kelulusan Etika (Pelajar Sarjana Perubatan) Lampiran 1 ‐ Senarai Permohonan Dinilai Dalam Mesyuarat JEPeM Tahun 2008 1. | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | 3 || LAPORAN TAHUNAN 2008 || Mesyuarat ke 199 (06 Februari 2008) Bil Nama Penyelidik Tajuk Kategori Dr. Liau Kai Ming A Pilot Study on the Usage of Medium Chain Triglyceride Sourced From Virgin Coconut Oil as a Food Supplement for the Management of Over‐Weight and Obese Subjects Selected Among Health Care Workers in Universiti Sains Malaysia Hospital. Geran Insentif 32. Dr. Abdul Nawfar bin Sadagatullah Honey dressing as a means of granulation promoter for wounds in patients with diabetic foot ulcers Geran Universiti Penyelidikan 33. Dr. Mohd Iskandar A Comparative study of the Effects of Madu Lebah Tualang on Healing of Traumatic Finger Tip Injury in Comparison with Paraffin Gauze Dressing Geran Universiti Penyelidikan 34. Dr. Abu Dzarr b Abdullah An open, Randomised, Controlled, Two‐Period Cross‐Over Study Comparing Honey to Ciprofloxacin as Prophylaxis Against Febrile Neutropenia in Patients with Haematological Malignancy Geran Universiti Penyelidikan 35. Dr. Wan Nudri Wan Daud Impact of Intensive Nutrition Education Program and Iron‐Folate Plus Vitamin C Supplementation on Iron Status and Cognitive Performance of Form 4 Students in Rural School in Tanah Merah Geran Jangka Pendek 36. Prof. Madya Dr. Biswa Mohan Biswal Phase‐II clinical trial on the use of Withania Somnifera (Aswagandha) in the Prevention of Chemotherapy‐Induced Fatigue among Breast Cancer Patients Geran Universiti Penyelidikan 37. Prof. Madya Dr. Biswa Mohan Biswal Multi‐center 3‐arm randomized controlled trial comparing efficacy of topical honey‐alginate versus topical pure natural honey, versus best supportive oral care in the management of radiation mucositis among patients undergoing radical radiotherapy for nasopharyngeal cancer. Geran Universiti Penyelidikan 38. Prof. Madya Dr. Rosline Hassan Detection of common deletional alpha‐Thalassaemia in pregnant lady by polymerase chain reaction Geran Universiti Penyelidikan 39. Prof.Madya Dr. Aida Hanum Ghulam Rasool Pharmacological and Non Pharmacological Interventions Benefial in Reducing Cardiovascular Risk in Obese Patients Geran Universiti Penyelidikan 40. Dr. Nik Hishamuddin Nik Ab Rahman Clinical Evaluation of 1‐Step Qualitative Heart‐Specific Fatty Acid Binding Protein (H‐FABP) test (CardioDetect®) and Quantitative Cardiac Troponin T, for the Diagnosis of Acute Myocardial Infarction in the Emergency Department. Geran Jangka Pendek 41. Dr. Juwita Shaaban Observational study to evaluate safety and effectiveness of the free combination of and 80mg/160mg valsartanamlodipine 5mg/10mg in the treatment of hypertension. Kajian Klinikal 42. Prof. Madya Rusli Ismail A Comparative Bioequivalence Study of Generic Pharmaniaga Doxycycline Capsule and the Proprietary Vibramycin Tablet (100mg of doxycycline). Kajian Klinikal 43. Prof. Madya Dr Shaiful Bahari Ismail A 76‐week, Worldwide, Multicenter, Double‐blind, Randomised, Placebo‐controlled Study to Assess the Tolerability and Efficacy of Anacetrapib When added to ongoing Therapy With a Statin in patients with Hypercholesterolaemia or mixed Hyperlipidaemia. Kajian Klinikal 44. Prof. Dato' Dr Mafauzy Mohamed A Randomized, Double‐Blind, Placebo‐Controlled, Double Dummy, Parallel Group, Multicenter, Dose Ranging Study in Subjects with Type 2 Diabetes Mellitus to Evaluate the Efficacy, Safety, and Tolerability of Orally‐Administered SGLT2 Inhibitor JNJ‐28431754 with Sitagliptin as a Reference Arm Kajian Klinikal 45. Dr. Nik Khairani Nik Mohd A study on prevalence of hearing impairment and associated factors among army personnel in Kelantan Kelulusan Etika (Pelajar Sarjana Perubatan) 46. Dr. Baharudin Abdullah Epilepsy and Obstructive Sleep Apnea Syndrome(OSAS) Geran Universiti Penyelidikan 47. Dr. Azhar Amir Hamzah Transurethral resection of prostate (TURP) in Hospital Universiti Sains Malaysia (HUSM): A retrospective study Kelulusan Etika (Pelajar Sarjana Perubatan) 48. Dr. Sarimah Mohd Mokhtar Usage of dental general anesthesia and dental fear survey at two tertiary centers in Kota Bharu, Kelantan Kelulusan Etika Sahaja 49. Dr Roziah Dali MR Volumetry study of Hippocampus and Temporal lobe in Malay adult with normal MRI brain in HUSM 50. Dr. Goh Chin Buan A study of quality of life in children with cancer in Hospital Universiti Sains Malaysia, Kelantan, Malaysia 51. Prof. Madya Dr. Kamaliah Mohd Daud A study on dyslipidemia in patients with end stage renal disease on dialysis in Kelantan 52. Dr. Mohd Suhaimi Abd Wahab Blood lead level among paediatric thalassaemia patients in Kota Bharu, Kelantan 53. Pn. Soon Lean Keng Traditional postpartum practices among the malays and Chinese in Malaysia Vis‐à‐vis Midwifery Practice 54. Dr. Fadhli Mustaffa Gastrointestinal stromal tumour (GIST)‐ A clinicopathological analysis of cases in HUSM 55. Dr. Normawati Mat Said Comparison of successful arteriovenous fistula between preoperative vascular mapping and physical examination in HUSM 56. Prof. Madya Dr. Rosline Hassan Isolation and characterization of mesenchymal stemm cell from human placenta Geran FRGS 57. Dr. Azlina Ishak Prevalence of metabolic syndrome (MS) among polycystic ovarian syndrome (PCOS) patients and its associated factor at Gynecology clinic, HUSM Kelulusan Etika (Pelajar Sarjana Perubatan) Kelulusan Etika (Pelajar Sarjana Perubatan) Kelulusan Etika (Pelajar Sarjana Perubatan) Kelulusan Etika (Pelajar Sarjana Perubatan) Kelulusan Etika (Pelajar Sarjana Perubatan) Lampiran 1 ‐ Senarai Permohonan Dinilai Dalam Mesyuarat JEPeM Tahun 2008 31. Kelulusan Etika (Pelajar PhD) Kelulusan Etika (Pelajar Sarjana Perubatan) Kelulusan Etika (Pelajar Sarjana Perubatan) | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | 4 || LAPORAN TAHUNAN 2008 || Mesyuarat ke 200 (05 Mac 2008) Bil Nama Penyelidik Tajuk Kategori Dr. Yvonne Tee Get Bee The Implication of Overweight on Microvascular Endothelial Function Assessed Using Iontophoresis‐Laser Doppler Fluximetry (IONTO+LDF) Measurement Model. Geran Jangka Pendek 59. Dr. Sam'an Malik Masudi An in‐vitro cross‐sectional assessment of apical sealing ability of USM nano‐HA sealer with Cold lateral & warm vertical techniques Geran Jangka Pendek 60. Dr. Mohamad Nazman Khamis Effect of the sea cucumber extract and TCA (trichloroacetic acid) in the healing process of the tympanic membrane perforation‐ Pilot study. Kelulusan Etika Sahaja 61. Dr. Amutha Santhanam Immunoproteomics of Helicobacter Pylori Infection in Different Gastric Pathologies: Towards the Identification of Diagnostic Markers Geran Universiti Penyelidikan 62. Dr. Wan Daud Wan Kadir A Comparative Study of Dexmedetomidine and Propofol for Sedation in Severe Traumatic Brain Injured Patients Kelulusan Etika Sahaja 63. Dr. Shaifulizan Abd Rahman The Comparison Between The Effect of Flapless and Full‐Thickness Flap Techniques on Crestal Bone Resorption and Osseointegration Geran Jangka Pendek 64. Dr. Habsah Hassan Multifaceted Approach of Hospital Associated Infections Control Programme (MAHAICP): Towards Zero Tolerance HAI Geran Universiti Penyelidikan 65. Dr. Che' Wan Aminud‐din Hashim Safety and efficacy of Honey as A Suplementary Therapy for Chronic Obstructive Pulmonary Disease(COPD) Geran Universiti Penyelidikan 66. Dr. Nik Hishamuddin Nik Ab Rahman Intramuscular promethazine versus prochloperazine for treatment of acute vertigo in emergency department: A randomized clinical trial Kelulusan Etika Sahaja 67. Dr. Wan Nazaruddin Wan Hassan A comparison between intravenous Parecoxib‐Patient Controlled Analgesia (PCA) combination and PCA morphine for postoperative analgesia following craniotomy Kelulusan Etika Sahaja 68. Prof. Madya Dr Shaiful Bahari Ismail A randomized, double blind, placebo controlled study evaluating the glycaemic effect of rimonabant added to metformin in patients with type 2 diabetes insufficiently controlled with metformin monotherapy‐TOCCATA Kajian Klinikal 69. Prof. Dato' Mafauzy Mohamed A randomized, double‐blind, placebo controlled parallel group efficacy and safety study of BI1356 (5mg administered orally once daily) over 24 weeks, in drug naïve or previously treated (6 weeks washout) type 2 diabetic patients with insufficient glycaemic control Kajian Klinikal 70. Dr. Ventakash R. Naik Study of Neoangionesis and Profilerative Cell Marker in Colorectal Carcinoma Geran Jangka Pendek 71. Prof. Madya Rusli Ismail A study to Compare the Bioavailability of TWO Amplodipine Oral Dosage Forms. Kelulusan Etika Sahaja 72. Prof. Madya Rusli Ismail A Study to Compare the Bioavailability of TWO Carvedilol Oral Dosage Forms. Kelulusan Etika Sahaja 73. Dr. Wan Zuraida Wan Ab Hamid A Study of Lymphocyte Subsets, Activation Markers, and Herpes Viruses infection in Epileptic Patients in HUSM Geran Universiti Penyelidikan 74. Dr. Ananda Dorai The Characteristics of Paediatric Burns in Kelantan Geran Jangka Pendek 75. Dr. Zairuddin Abdullah Zawawi Incidence of subclinical deep vein thrombosis in lower extremeties following cast immobilization 76. Dr. Cheah Phee Keng Usefulness of Capnography in patients with shock : Correlation between End‐Tidal Carbon Dioxide and Patients with Shock Presenting to Emergency Department 77. Dr. Halimatun Mansor The Obstetric outcomes in Primiparity and Multiparity on Epidural Analgesia In HUSM 78. Dr. B. Vicknasingam A Prospecitve Survey Comparing Injecting Buprenorphine/Nalaxone Users and Heroin Users in Malaysia Kelulusan Etika Sahaja 79. Cik Kasmah Wati The Effectiviness of Online and Face‐to‐face Problem‐Based Learning on the Perfomance of Undergraduated Students in a Health Science Course Geran Jangka Pendek 80. Dr. Hairul Anuar Hashim Psychometric Validation of Selected Sport Psychology Questionnaires Geran Jangka Pendek 81. Prof. Madya Dr. Shah Reza Johan A Study on Red Blood Cell Alloantibodies in Malay Women During Pregnancy Geran Jangka Pendek Kelulusan Etika (Pelajar Sarjana Perubatan) Kelulusan Etika (Pelajar Sarjana Perubatan) Kelulusan Etika (Pelajar Sarjana Perubatan) 82. Dr. Shahidi Jamaludin A comparative study on diagnostic accucary of reused CLO test and reused Pronto‐Dry in the diagnosis of helicobacter pylori infection. Kelulusan Etika (Pelajar Sarjana Perubatan) 83. Dr. Zainul Ahmad Rajion Variations in Tooth Size, Dental arch dimensions and shape among Malay Schoolchildren Geran Jangka Pendek 84. Dr. Mohd Nazri Shafei Knowledge, Attitude and Practice (KAP) & Associated Factors for Leptopsirosis Among Workers of Kota Bharu Municipal Council (MPKB), Kelantan Malaysia Geran Jangka Pendek Lampiran 1 ‐ Senarai Permohonan Dinilai Dalam Mesyuarat JEPeM Tahun 2008 58. | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | 5 || LAPORAN TAHUNAN 2008 || Mesyuarat ke 201(09 April 2008) Bil Nama Penyelidik Tajuk Kategori Dr. Amran Ahmed Shokri A Phase III Randomized, Double Blind, Parallel‐Group Study of the Efficacy and Safety of Oral Dabigatran Etixilate (150 mg bid) compared to Warfarin (INR 2.0‐3.0) for 6 Month Treatment of Acute Symptomatic VenousThromboembolism Following Initial Treatment for At Least 5 days with a Parenteral Anticoagulant Approved for this Indication. Kajian Klinikal 86. Dr. Mohamed Saat Ismail Effects of Exercise Frequency on Hypercholesterolemic Individuals Geran Jangka Pendek 87. Prof. Madya Dr. Norazah Mohd Yusoff Reliability of N‐terminal Pro‐B Type Natriuretic peptide in the diagnosis of congental heart disease. Geran Universiti Penyelidikan 88. Dr. Aravazhi Ananda Dorai A Comparative Study of Honey Hydrogel With Safecare Hydrogel Dressing in the Treatment of Split Skin Graft Donor Sites. Geran Jangka Pendek 89. Prof. Madya Dr. Noryati Ismail Risk Assessment of Aflatoxins in Nuts and Nut Products In Penang Kelulusan Etika Sahaja 90. Dr. P.T. Jayaprakash Cranio‐facial personal identification of unidentified human remains Geran Universiti Penyelidikan 91. Dr. Arman Zaharil Mat Saad Randomized Double‐Blinded Trial to Study The Efficacy of Topical Chitosan in the Prevention of Hypertrophic Scars in the Superficial Dermal Wound (Burns Scar and Split Thickness Graft Donor Area). Geran Jangka Pendek 92. Prof. Madya Wan Ahmad Kamil Wan Ahmad Determination of apparent Diffusion Coefficient of Blood at Various Age Using the Technique of Diffusion MRI Geran Jangka Pendek 93. Dr. Rashidi Ahmad A randomised controlled trial comparing the effectiveness of Tramadol/ Paracetamol and Codeine Phosphate/ Paracetamol as early analgesia at triage counter for moderate pain Geran Jangka Pendek 94. Dr. Noorizan Hj Abd Hamid Susceptibility of Helicobacter pylori infection, among Kelantanese population Geran Universiti Penyelidikan 95. Prof. Madya. Khor Yoke Lim Examining Media Technology Impact on Health Decision Making Geran Universiti Penyelidikan 96. Prof. Dr. Zulkurnai Yusof Participation in SeQuent Please International Registry Kajian Klinikal 97. Dr. Zarina Zainan Abidin Honey as a supplementary theraphy for patients with Depression Kelulusan Etika Sahaja 98. Prof. Mohd Razali Salleh Detection and Intervention of Schizophrenia in the Prodromal Phase Geran Universiti Penyelidikan 99. Dr. Erry Mochamad Arief Pembentangan Berkaitan Rumusan Projek Elektif Pelajar Sarjana Muda Pergigian Tahun 4. Kelulusan Etika Sahaja 100. Prof. Dr. Ravindran Ankathil Identification of predisposition genotypes that contribute to colorectal cancer susceptibility in Malaysia Geran Universiti Penyelidikan 101. Prof. Dr. Ravindran Ankathil Influence of genetic variation of NFkB1A genotype in sporadic colorectal cancer risk among 3 ethnic population subgroups of Malaysia Geran Universiti Penyelidikan 102. Dr. Wan Azman Wan Sulaiman Soft Tissue Characteristic of Repaired Cleft Lip and Palate in Kelantan. Geran Jangka Pendek 103. Dr. Win Mar @ Salmah Jalaluddin Normative Data for Hippocampal and Temporal Lobe Volume in Normal Malay Population Geran Universiti Penyelidikan 104. Dr. Juwita Shaaban Validation of Malay Version of Rowland University Dementia Assessment Scale (Rudas) Among Elderly in Klinik Kesihatan Bandar Kota Bharu Geran Jangka Pendek 105. Dr. Sakinah Harith The Effectiviness of nutritional counselling for diabetic patients in outpatient dietetic clinic, HUSM : A preliminary study Kelulusan Etika Sahaja 106. Prof. Madya Dr. Nik Hazlina Nik Hussain Prevalence of Metabolic Syndrome (MS) postmenopausal Women and Its Associated Factors at Gynaecology Clinic, HUSM Geran Jangka Pendek 107. Dr. Mohd Fadhli Khamis The accuracy of Gustafson and Johanson age estimation methods for malay adults in Kelantan Geran Jangka Pendek 108. Dr. Shaik Farid Abdull Wahab Ultrasonography measurement of Inferior Vena Cava diameter of blood donors in HUSM Kelantan Geran Jangka Pendek 109. Dr. Norizan Kamarudin Evaluation on the performance of visual inspection of acetic acid (VIA) in comparison with conventional cytology (PAP smear) test as a screening tool for cervical carcinoma Kelulusan Etika Sahaja 110. Dr. Amirozi Ahmad A study of outcome of newborn hearing screening programme in HUSM from January 2003 to Disember 2007 Kelulusan Etika (Pelajar Sarjana Perubatan) 111. Dr. Norwati Bt Daud A study on obesity and cardiovascular risk factors among male soldiers in Melaka Malaysia Geran Jangka Pendek 112. Dr. Harmy Mohamed Yusoff A study on suboptimization of cardiovascular screening among apparently healthy post menopausal women in Malaysia Geran Universiti Penyelidikan 113. Dr. Anuar Waid Prevalence of irritable Bowel Syndrome (IBS) among normal healthy volunteers using validated Bahasa Malaysia ROME III (IBS) questionnaire. Kelulusan Etika (Pelajar Sarjana Perubatan) Lampiran 1 ‐ Senarai Permohonan Dinilai Dalam Mesyuarat JEPeM Tahun 2008 85. | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | 6 || LAPORAN TAHUNAN 2008 || Mesyuarat ke 202 (15 Mei 2008) Bil Nama Penyelidik Tajuk Kategori Dr. Julia Omar Comparison of Serum Cystatin C with Creatinine Clearance and Estimated Glomerular Filtration Rate as a Marker for Detection of Early Renal Impairment in Type 2 Diabetes Mellitus Patients Geran Jangka Pendek 115. Dr. Maizurah Omar Evaluating the efficacy of real‐life video and animated cartoon in empowering young children towards creating a behavioral change among smoking parent. Kelulusan Etika Sahaja 116. Prof. Rosni Abdullah Hardware/Software and Middleware/ Training for Data Driven Research on Remote Supercomputing Facilities –MP@ Satellite Facility with Datamatique Quascade‐MP2 Server. Kelulusan Etika Sahaja 117. Dr. Kamarul Aryffin Baharuddin The Efficacy of IV Parecoxib Sodium As An Analgesic Alternative to Morphine in Acute Trauma Pain : A Randomized Clinical Trial. Geran Jangka Pendek 118. Dr. Lee Yeong Yeh The Prevalence and Associated Risk Factors of Clostridium difficile Infection in Patient with Diabetes mellitus Treated with Antibiotic. Geran Jangka Pendek 119. Dr. Mawar Ayub Value of Shock Index in Risk Stratification of Illness Severity Among Patients in Emergency Department. Kelulusan Etika Sahaja 120. Dr. Nik Shairuzli Nik Hassan A Randomized controlled trial of combined Sodium and Ultrafiltration Profiling in patient on chronic Haemodialysis Kelulusan Etika Sahaja 121. Prof. Madya Dr. Zilfalil Alwi DNA Profiling of the Malaysian Population using Microarray. Geran Universiti Penyelidikan 122. Dr. Nor Aizal Che Hamzah Prevalence of Non‐Alcoholic Fatty Liver Disease (NAFLD) in Patients with Metabolic Syndrome and its Associated Risk Factors in HUSM. Geran Jangka Pendek 123. Dr. Mohd Ezane Aziz Colour Doppler ultrasound with spectrum analysis for assessment of chemotherapy response in Osteosarcoma. Geran Jangka Pendek 124. Dr. Asilah Yusof Pengesahan Pembentangan Program Elektif Pelajar Fasa III Tahun 4, Pusat Pengajian Sains Pergigian. [Phase III Year 4 Elective Programme Academic Session 2007/2008]. Kelulusan Etika Sahaja 125. Dr Tengku Alina Tengku Ismail Knowledge, Attitude and Practice of Breasfeeding Among Female Staff in Health Campus, Kelantan Geran Insentif 126. Dr. Juliana Mohamad Basuni Retrospective analysis of Prolonged Second Stage Outcomes in HUSM. 127. Dr. Siti Aishah Ahmad Maulana A study of relationship of vascular pedicle width and cardiothoracic ration in adult pulmonary edema patient during treatment in ICU. 128. Dr. Sudhagar Krishinan Cost Effectiveness in Management Of Open Fracture Tibia Grade 3A. 129. Dr. Jasvindar Singh a/l Jagindar Singh Outcome Of Immediate Weight Bearing Femoral Shaft Fractures Treated By Single Locked Intramedullary Nailing. 130. Dr. Seyed Ahmad Taheri Association between computed tomography grading scales of aneurysmal subarachoid haemorrhage and outcome results. 131. Dr. W. Mohd Zahiruddin W. Mohammad Review of Tuberculosis Contacts Investigations in Hospital USM Geran Insentif 132. En. Madhavan a/l Raman Kutty Studies to Determine Platelet Activation as a Predictor of Preeclamptic toxaemia by Flow Cytometer. Geran Jangka Pendek 133. Dr. Zainul Ahmad Rajion The nature and extent of asymmetry between right and left human temporomandibular joints. Kelulusan Etika Sahaja 134. Prof. Dato’ Wan Mohamad Wan Bebakar Usefulness of Arm Fat as a Predictor for Lipid, Glucose and Blood Pressure Patients with Metabolic Syndrome. Geran Jangka Pendek 135. Dr. Harmy Mohamed Yusoff A study of Knowledge, Practice and Barriers and the use of Immunological Faecal Occult Blood Test as a Screening Tool for Colorectal Cancer in Moderate Risk Malay Population Attending Health Clinic in Kelantan. Geran Universiti Penyelidikan 136. Dr. Che' Wan Aminud‐din Hashim Features and Pathogens in Community Acquired Pneumonia (CAP). Geran Jangka Pendek 137. Dr. Izety Shazlinda bt Noran Analysis of Nasalance Score among Malay Cleft Lip Palate Post Palatoplasty and its Association with Age, Gender, Type of Cleft, Speech Therapy and Operative Technique. Kelulusan Etika Sahaja 138. Dr. Aziah Daud Prevalence, Associate Factors and Salivary Biomarker of Stress Among Assistant Medical Officers in Ministry of Health (MOH) Hospitals in Kelantan and Terengganu. Geran Jangka Pendek 139. Dr. Tan Bee Hwai Bone diseases and Radiographic Bone Age (RBA) in Thalassemia patients. Kelulusan Etika Sahaja 140. Dr. Rapiaah Mustaffa A comparison on human progenitor cells enumeration using sysmex hematology analyzer and standard flowcytometry. Geran Jangka Pendek Kelulusan Etika (Pelajar Sarjana Perubatan) Kelulusan Etika (Pelajar Sarjana Perubatan) Kelulusan Etika (Pelajar Sarjana Perubatan) Kelulusan Etika (Pelajar Sarjana Perubatan) Kelulusan Etika (Pelajar Sarjana Perubatan) Lampiran 1 ‐ Senarai Permohonan Dinilai Dalam Mesyuarat JEPeM Tahun 2008 114. | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | 7 || LAPORAN TAHUNAN 2008 || Mesyuarat ke 203 (04 Jun 2008) Bil Nama Penyelidik Tajuk Kategori Dr. Mohd Sapawi Mohamed Screening and Optimization of Denaturating High Perfomance Liquid Chromatography (DHPLC) for Screening of Mutation in the LDLR Gene in Patients with Familial Hypercholesterolemia. Geran Jangka Pendek 142. Dr. Maa Saung Oo Rectal Analgesia for Perineal Relief After Childbirth : A Randomized Controlled Trial of Diclofenac Suppositories vs Acetaminophen Suppositories Geran Jangka Pendek 143. Pn. Che Hasnah Che Soh Tahap pengetahuan, sikap dan amalan tentang penyusuan susu ibu dikalangan ibu‐ibu di wad pos natal HUSM. Geran Insentif 144. Prof. Madya Dr. Asok Kumar Ghosh Effects of Soy Protein Supplementation on High Intensity Cycling Performance in a Hot and Humid Environment Geran Jangka Pendek 145. Dr. Foo Leng Huat A Study of Determinants of Bone Health in Adolescent Boys and Girls in Kelantan. Geran Universiti Penyelidikan 146. Prof. Prabha Balaram Evaluation of Epstein‐ Barr Virus Proteins as Factors Leading to Down Regulation of DNA Damage Repair Proteins in Nasopharyngeal Carcinomas. Geran FRGS 147. Dr. Hairul Anuar Hashim The Effects of Exercise‐Induced Dehydration on Psychomotor and Physiological Variables in Relaxation‐Trained Army‐Reserved Personnel’s During Prolonged Walking in the Heat. Geran Universiti Penyelidikan 148. Dr. Hairul Anuar Hashim The Effects of Two Relaxation Techniques on Physiological, Physiological and Psychomotor 64Variables During Repeated M65aximal Intensity Activity Among School Athletes. Geran Jangka Pendek 149. Dr. T.P. Kannan Evaluation of Genotoxic Potential of Biomaterials on Stem Cells From Human Exfoliated Deciduous Teeth and Human Mesenchymal Stem Cells Using Comet Assay. Geran FRGS 150. Dr. Zainul Ahmad Rajion The Internal and External Tooth Morphology of Malays Geran FRGS 151. Prof. Dato' Mafauzy Mohamed An Outcome Research on the Impact of a Disease Management Program (Coach) on the Attainment of Better Cardiovascular Risk Control in Dyslipidemic Patients at Primary Care Centers (Disseminate). Kajian Klinikal 152. Dr. Mohamad Hadzri Yaacob Electroanalytical Studies and Voltammetric Determination of Antibiotic Drugs (Vancomycin) in Human Plasma Samples. Kelulusan Etika Sahaja 153. Dr. Hamid Jan Jan Mohamed Needs Assessment Survey on Nutrigenomics‐ Based Personalised Nutrition Among Dietitians in Malaysia. Kelulusan Etika Sahaja 154. Dr. Shaharum Shamsuddin A Study of The Transcription Factors CTCF/BORIS, YB‐1 and MDR‐1 in Osteosarcoma Tumour Samples. Kelulusan Etika Sahaja 155. Dr. Fatimah Zarina Jamaludin Incidence and Associated Factors For Hypertensive Disorders among Type 1, type 2 and Gestational Diabetes Mellitus Mothers. Kelulusan Etika Sahaja 156. Dr. Mohammad Nazir Md Hassan Relationship between intervertebral disc height, lateral foramen size and nerve root impingement of lumbar vertebral. 157. Dr. Devkumar a/l Mamasemayam Factor associated with the outcome of Kasai surgery among Extrahepatic Bile Duct Atresia patients in Hospital Alor Star from 1998 to 2006. 158. Dr. Menaga a/p Munusamy Pregnancy outcome in advanced maternal age: A retrospective study from 2000‐2007 (8 years) in HUSM. 159. Dr. Aida Azlin Puteri Bt Sallehudin Evaluation of Fetal heart rate as a predictor of fetal loss following first trimester threatened abortion. 160. En. Che Ismail Bin Che Lah A Study of Mitochondrial A1555G Mutation in Aminoglycoside Induced Sensorineural Hearing Loss Patient. Kelulusan Etika Pelajar Sarjana Perubatan) Kelulusan Etika Pelajar Sarjana Perubatan) Kelulusan Etika (Pelajar Sarjana Perubatan) Kelulusan Etika (Pelajar Sarjana Perubatan) Lampiran 1 ‐ Senarai Permohonan Dinilai Dalam Mesyuarat JEPeM Tahun 2008 141. Geran Jangka Pendek Mesyuarat ke 204 (16 Julai 2008) Bil Nama Penyelidik Tajuk Kategori Dr. Zakuan Zainy Deris Molecular Epidemiology and Reverse Transcriptase (RT) and Protease inhibitors (PR) Resistance Genotyping of Human Immunodeficiency Virus (HIV) In Kelantan. Geran Universiti Penyelidikan 162. Prof. Quah Ban Seng Intravenous Dexamethasone for Extubation in Newborn Infants. Geran Jangka Pendek 163. Dr. Ooi Foong Kiew Effects of Eurycome Iongifolia Jack Supplementation on Recreational Athletes Running Endurance Perfomance and Physiological Responses in the Heat. Geran Jangka Pendek 164. Dr. Noraida Ramli Prone Versus Supine Position in Mechanically Ventilated Neonates During First Postnatal Week: A Randomized Controlled Trial. Geran Jangka Pendek 165. Dr. Nasir Mohamad The Influence of Intravenous Promethazine On Intravenous Morphine for Acute Pain Management in the Emergency Department. A Randomised Clinical Trial. Geran Jangka Pendek 166. Dr. Aishah Knight The Socio‐Impact of Breast Cancer on the Female Patients and Her Family in Penang and Kelantan. Kelulusan Etika Sahaja 167. Dr. Aishah Knight The Use of Herbal Preparations Among Patients Receiving Palliative Care in Penang Island. Kelulusan Etika Sahaja | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | 161. 8 || LAPORAN TAHUNAN 2008 || Dr. Aishah Knight The Mapping of Colorectal & Breast Cancer Cases With Reference to the Location of Conventional Health Facilities. Kelulusan Etika Sahaja 169. Prof. Dato’ Wan Mohamad Wan Bebakar A Randomized, Double‐Blind, Placebo‐Controlled, Parallel‐Group, Multicenter, 24‐Week Study Followed by an Extension Assessing The Efficacy and Safety of AVE0010 in two Titration Regimens on top of Metformin in Patients With Type 2 Diabetes Not Adequately Controlled with Metformin Kajian Klinikal 170. Prof. Abdul Aziz Baba A Multicenter, Double Blind, Placebo Controlled, Randomized Study of TroVax ® vs. Placebo in the First Line Treatment of Patients with Metastatic Colorectal Cancer Receiving Standard of Care. Kajian Klinikal 171. Prof. Dato’ Mafauzy Mohamed A Phase IIb/III, Multicenter, Randomized, Double‐Blind, Placebo‐Controlled Dose‐Range Finding Clinical Trial of MK‐0941 in Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Insulin Kajian Klinikal 172. Prof. Dato’ Mafauzy Mohamed A Phase 3, Randomized, Double‐Blind, Placebo‐Controlled, Multi‐Center Study to Evaluate Safety and Efficacy of PHX1149T as Monotheraphy in Subjects With Type 2 Diabetes Mellitus Kajian Klinikal Kelulusan Etika (Pelajar Sarjana Perubatan) Kelulusan Etika (Pelajar Sarjana Perubatan) 173. Dr Fauzi B Che Hussin Standard Precautions: Knowledge, Attitude and Practice among Healthcare Personnel in Emergency Department, Hospitals in Kelantan 174. Dr. Lim Chee Kean A Survey of the Acceptability of Allowing Presence of Relatives During adult Resuscitation Among Malaysian Emergency Personnel. 175. Kartini Abdul Karim Amalan Penyusuan Ibu dan Corak Pemakanan Pelengkap di Kalangan Bayi Berumur 6 Hingga 24 Bulan Yang Hadir ke Klinik Kesihatan Kuala Terengganu. Geran Jangka Pendek 176. Dr. Kamarul Imran Musa The Omega‐3 and Omega‐3 Index Blood levels and their Association with Demographic, Clinical Characteristics, Fasting Blood Sugar and Lipid Profiles Among Health Staffs Population. Geran Universiti Penyelidikan 177. Dr. Noriyana Mohamed Yusof Pre‐operative Evaluation of Doppler Ultrasonography in Comparison to Risk Malignancy index (RMI) in ovarian masses scheduled for surgery. Kelulusan Etika (Pelajar Sarjana Perubatan) 178. Dr. Norlida Ibrahim Respiratory Symptoms and Pulmonary Functions Among Domestic Waste Collectors in Kota Bharu, Kelantan. Geran Jangka Pendek 179. Dr. Moharzudi Mohamed The outcome of breast cancer based on the expression of estrogen receptor, progesterone receptor and C‐erbB2: Kelantan experience 2002‐2004. 180. Dr. Roslan Ridzuan Retrospective five years analysis of Dexamethasone therapy in preterm pregnancy admitted to HUSM from the year 2003 to 2007. 181. Cik Ruqayyah Muhammad Kajian pengetahuan, sikap dan amalan kebersihan dan sanitasi dikalangan pengendali makanan di premis‐premis makanan sekitar kampus kesihatan USM 182. Dr. Azlan Kamalludin Comparison between serum lactate and leukocyte count as a predictor of mortality in emergency department patients with infection. 183. Dr. Harshinderjeet Singh a/l Jeswant Singh The validity and the reliability of the malay version of the Scoliosis Research Society‐ 22 (SRS) patient questionnaire. 184. Dr. Muhamad Saiful Bahri Yusoff Prevalence and sources of stress among medical students in Universiti Sains Malaysia. Geran Jangka Pendek 185. Dr. Ruban Sivanoli Factors that determine patient Satisfaction post corrective osteotomy of Malunited supracondylar humerus paediatric fractures in Kota Bharu, Kelantan between 2002‐2007. Kelulusan Etika (Pelajar Sarjana Perubatan) Kelulusan Etika (Pelajar Sarjana Perubatan) Kelulusan Etika (Pelajar Sarjana Perubatan) Geran Insentif Kelulusan Etika (Pelajar Sarjana Perubatan) Kelulusan Etika (Pelajar Sarjana Perubatan) Lampiran 1 ‐ Senarai Permohonan Dinilai Dalam Mesyuarat JEPeM Tahun 2008 168. Mesyuarat ke 205 (27 Ogos 2008) Bil Nama Penyelidik Tajuk Kategori Dr. Nasir Mohamad A Comparative and Pharmacogenetic Study of Carvedilol, Metoprolol and Propranolol in the Management of Congestive Heart Failure Kelulusan Etika Sahaja 187. Dr. Shafini Mohamed Yusoff Flow Cytomeric Analysis of Nuclear DNA Ploidy and Proliferative Activity in Acute Lymphoblastic Leukaemia Geran Jangka Pendek 188. Prof. Madya Siti Hawa Ali Health Impact of Violence Against Women (Domestic Violence) in Malaysia : Replication of Who Multi‐Country Study On Women’s Health and Domestic Violence Against Women Geran Universiti Penyelidikan 189. Dr. Yvonne Tee Get Bee The Study of Plaque Instability Indicators in Patients With Acute Coronary Syndrome Geran Universiti Penyelidikan 190. Dr. Nik Mohd Rizal I‐PBL : A Proposed Project of Interactive and Integrated Problem Based Learning (PBL) for Undergraduate Medical Teaching utilising Standardised/Simulated Patients (SPs) at the Clinical Skills Centre in School of Medical Sciences, Universiti Sains Malaysia Geran Universiti Penyelidikan 191. Dr. Che Wan Mohd Shaifulnizam Factors Determining The Length of Over Penetration During Drilling Procedure With K wire and Drill Bit among Orthopaedic’s Master Student Universiti Sains Malaysia 192. Dr. Puteri Nurbaya Mohamed Ismail Comparison of Inflammatory Markers in Patients With and Without Fixed Airflow Limitation in Severe Asthma in Hospital Universiti Sains Malaysia 193. Dr. Zuraida Zainun A Study of The Neurocognitive Status in Patients With Peripheral Vestibular Disorders (PVD) Using Selected Neurological Tests Geran Universiti Penyelidikan 194. Prof. Madya Dr. Mohd Jamil Yaakob Pharmacoepidemiologic International Longitudinal Antipsychotic Registery. Kajian Klinikal | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | 186. Kelulusan Etika (Pelajar Sarjana Perubatan) Kelulusan Etika (Pelajar Sarjana Perubatan) 9 || LAPORAN TAHUNAN 2008 || Prof. Madya Dr. Mohd Jamil Yaakob A Multi‐Center, Retrospective, Comparative Study to Investigate Drug Utilization Patterns And Treatment Period Associated With Atypical Antipsychotics Treatment in Schizophrenia and Schizoaffective Disorders: Aripiprazole,Olanzapine,Quetiapine and Risperidone. Kajian Klinikal 196. Prof. Dato’ Mafauzy Mohamed A 78 Week, Open Label Extension To Trials Assessing the safety and Efficacy of BI 1356 (5mg) as monotherapy or in combination with other antidiabetic medications in type 2 diabetic patients. Kajian Klinikal 197. Dr. Karen Jeet Kaur A/P Kartar Singh Prevalence of Anal Incontinence in Patients with Pelvic Organ Prolapse and its Effects on Lifestyle Impact in Hospital Ipoh. Kelulusan Etika (Pelajar Sarjana Perubatan) 198. Dr. Hamid Jan Jan Mohamed The association between Serum Adiponectin, Body Mass Index (BMI) and Waist‐hip Ratio in Normal Weight and Obese Individuals. Kelulusan Etika Sahaja 199. Dr. Hamid Jan Jan Mohamed Metabolic Syndrome risk factors: A Study on the Association with diet and Genetic Factor. Kelulusan Etika Sahaja 200. Dr. Shamizi Mohamed Recurrent Gestational Diabetes Mellitus‐ A Cross‐sectional Study in HUSM. Kelulusan Etika (Pelajar Sarjana Perubatan) 201. Dr. Mohd Nazri Shafei The association of Shift Work and Metabolic Syndrome Among Nurses in HUSM, Kubang Kerian, Kelantan, Malaysia Geran Jangka Pendek 202. Prof. Dr. Zulkifli Ahmad Malnutrition and its Association Factors Among Primary One School children in Rural Tanah Merah, Kelantan. Geran Jangka Pendek 203. Dr. Ashraf Sharifuddin Role of Serial Head Computed Tomography imaging in the management of mildhead injury patients with positive head CT. 204. Dr. Suryawan Tasref Retrospective Cross‐sectional Study for Completeness of Anaesthetic form (in pre operative assessment section). 205. Dr. Mohd Hashairi Fauzi A Survey on Knowledge, Attitude and Practice of Adult Cardiopulmonary Resuscitation (CPR) among Junior Doctors in HUSM and HRPZII. 206. En. Mohd Sapuan Baharuddin Survival Rate and Prognostic Factors of Adult Human Immunodeficiency Virus in Hospital Universiti Sains Malaysia from 1996 to 2006. 207. Cik Nuradhiathy Abd Razak 5 Year Survival Rate and Prognostic Factors of Cervical Cancer in Hospital Universiti Sains Malaysia Kelulusan Etika (Pelajar Sarjana Perubatan) 208. Dr. Fauziah Jummaat Sensitivity and Specificity of Cystatin C in Detecting Early Renal Impairment in Hypertensive Pregnancies. Geran Jangka Pendek 209. Dr Nik Norliza Nik Hassan Investigation of CTCF gene expression by Taqman based Real Time PCR. Geran Jangka Pendek 210. Cik Siti Noraini Sulaiman Development of an Intelligent Screening System for Cervical Cancer Kelulusan Etika (Pelajar Sarjana Perubatan) Kelulusan Etika (Pelajar Sarjana Perubatan) Kelulusan Etika (Pelajar Sarjana Perubatan) Kelulusan Etika (Pelajar Sarjana Perubatan) Kelulusan Etika (Pelajar Sarjana Perubatan) Lampiran 1 ‐ Senarai Permohonan Dinilai Dalam Mesyuarat JEPeM Tahun 2008 195. Mesyuarat ke 206 (29 Oktober 2008) Bil Nama Penyelidik Tajuk Kategori Dr. Aravazhi Ananda Dorai A Comparative Study on the Clinical Application of Cultured Epidermal Autografts (CEA) and Cultured Epidermal Allografts (CEAllo) on Burn Patients Kelulusan Etika Sahaja 212. Dr. Darhaysyam Al‐Jefri Mohamed Muslim Performance of Osteoporosis Self‐Assessment Tool for Asian (OSTA) for Osteoporosis in Post‐Menopausal Malay Women In Hospital Universiti Sains Malaysia Geran Jangka Pendek 213. Prof.Madya Dr. Zurkurnai Yusof A Randomized, Double‐Blind, Active‐Controlled, Multicenter Study of Patients with Primary Hypercholesterolemia and High Cardiovascular Risk and not Adequately Controlled with Atorvastatin 20 mg: A Comparison of Switching to a Combination Tablet Ezetimibe/Simvastatin (10mg/40mg) versus Doubling the Baseline Dose to Atorvastatin 40 mg Kajian Klinikal 214. Dr. Erlina Sih Mahanani Efficacy of Salvadora persica in reducing caries risk factors Geran Jangka Pendek 215. Prof. Dr. Ahmad Sukari Halim Randomized Double‐Blinded Trial To Study The Efficacy Of Topical Herbal Product ‐ Curcuma Xanthorrhiza (Temulawak) in The Prevention Of Hyperpigmented Scar For Split Skin Graft Donor Area. Kelulusan Etika Sahaja 216. Dr. B. Vicknasingam Assessment of QOL (Quality of Life) and RB (risk behaviour) in IDUs after attending Behavioral Drug and HIV Risk Counseling for Needle‐Syringe Exchange Program. Kelulusan Etika Sahaja 217. Dr. Mohd Nikman Ahmad Dr. Nizar Abd Jalil A Randomized Controlled Trial On Comparison Between ElastrometricPump (On‐Q Pain Relief System) & Patient Controlled Analgesia (PCA) for Postoperative Pain Relief After Median Sternotomy Kelulusan Etika Sahaja 218. Dr. Gam Lay Harn Method Development for Isolation and Identification of Proteins Extracted from Breast Carcinoma Geran Science Fund 219. Assoc Prof Dr Shahid Hassan Evaluation of Proposed 4‐S Model as Self‐directed Method of Clinical Skills Learning for Undergraduate Medical Teaching Utilizing Standardized/Simulated Patients (SP) in School of Medical Sciences, Universiti Sains Malaysia. Geran Jangka Pendek | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | 211. 10 || LAPORAN TAHUNAN 2008 || Prof. Dato’ Wan Mohamed Wan Bebakar A Worldwide, Multicenter, Double‐Blind, Randomized, placebo‐Controlled, Dose Ranging Study to Evaluate the efficacy, safety and Tolerability of MK‐0736 When Added to Ongoing Therapy With Angiotensin‐Converting Enzyme (ACE) Inhibitor or Angiotensin Receptor Blocker (ARB) in Patients With Diabetes and Hypertension. Kajian Klinikal 221. Dr. Radiah Yusoff Pengubahsuaian Pendekatan Analisis Perbualan Ten HAVE (1999), WILKINSON (1999) dan BEEKE et. al. (2001) Untuk Menganalisis Gangguan Bahasa Dalam Kalangan Pesakit Kecederaan Otak (KOT) di USM. Geran Universiti Penyelidikan 222. Prof. Dr. Lokman Mohd Noh A Multicentred Prospective Study on Incidence, Prevalence, Clinical Characteristic and Outcome of Primary Immunodeficiency (PI) Disorders ws Among Malaysian With Recurrent Infections. Geran Universiti Penyelidikan 223. Prof. Madya Siti Hawa Ali Health impact of Violence Against Women (Domestic Violence) in Malaysia: Replication OD WHO Multi‐Country Study on Women’s health and Domestic Violence Against Women. Geran Universiti Penyelidikan 224. Dr. Md. Anayet Ullah Undergraduate Medical Student Attitudes Towards Communication Skills Teaching and its Determinants in Universiti Sains Malaysia. Geran Jangka Pendek 225. Dr. Wan Haslindawani Wan Mahmood Motivators and Barriers to Blood Donation in HUSM Geran Jangka Pendek 226. Dr. Osama Saleh Alawi The Effect of Diabetes Mellitus On The Outcome of Arteriovenous Fistula (AVF) in Hospital University Sains Malaysia from 2001 to 2005. Kelulusan Etika (Pelajar Sarjana Perubatan) 227. Dr. Shaharudin Abdullah Clinical and Economic Burden of Pneumococcal Disease in Malaysia Kelulusan Etika Sahaja 228. Dr. Rohana Abd Jalil Maternal‐child Nutrition Status and Its Association with Food Insecurity Among Low Income Household: Identification of Dual Malnutrition in Bachok District, Kelantan. Geran Universiti Penyelidikan 229. Dr. Zuraida Zainun A Study For Enhancing The Diagnosis of Peripheral Vestibular Disorders Kelulusan Etika (Pelajar Sarjana Perubatan) 230. Dr.Tengku Alina Tengku Ismail Role of Serial Head Computed Tomography imaging in the management of mildhead injury patients with positive head CT. Geran Universiti Penyelidikan 231. Dr. Ikhwan Sani Mohamad Post Operative Morbidity and 3 Years Survival Rate in Diabetic and Non Diabetic Patients Undergoing Coronary Artery Bypass Grafting in Hospital Universiti Sains Malaysia. Kelulusan Etika (Pelajar Sarjana Perubatan) 232. Pn. Norhaniza Abdul Khairi Pembentangan Rumusan Projek Penyelidikan Pelajar Tahun Akhir Patologi Pertuturan Sesi 2008/2009. Kelulusan Etika Sahaja 233. Dr. Mohd Normani Zakaria Pembentangan Rumusan Projek Penyelidikan Tahun Akhir Audiologi Sesi 2008/2009. Kelulusan Etika Sahaja 234. En. Nurul Azuar Hamzah Pembentangan Rumusan Projek Penyelidikan Tahun Akhir Program Sains Senaman dan Sukan 2008/2009. Kelulusan Etika Sahaja Lampiran 1 ‐ Senarai Permohonan Dinilai Dalam Mesyuarat JEPeM Tahun 2008 220. Mesyuarat ke 207 (26 Nov 2008) Bil Nama Penyelidik Tajuk Kategori Dr. Azriani Ab.Rahman Prevalence and Factors Associated With Premarital Sexual Activity Among Secondary School Students in Bachok, Kelantan. Geran Universiti Penyelidikan 236. Dr. Lim Boon Huat Intervention Model For Controlling Soil‐Transmitted Helminthiasis Among Lower Primary Schoolchildren In Bachok Kelantan. Geran Universiti Penyelidikan 237. Pn. Noor Aini Hussain The Impact of A Community‐Based Supportive Educative Learning (CSEL) Program on Family Caregivers of Home ‐Based Stroke Survivors In Kelantan. Geran Universiti Penyelidikan 238. S. Daniel Robert Investigation of Fruits & Vegetable Consumption by the Bachok Population in Kelantan, Malaysia. Geran Universiti Penyelidikan 239. Pn. Rosmawati Mohamed The Evaluation of Supportive‐Developmental Nursing Program On Self‐Care Practices of Persons With Type 2 Diabetes at The Health Centre in Bachok, Kelantan Geran Universiti Penyelidikan 240. Prof. Wan Abd Manan Wan Muda The Efficacy of Pedometer ‐Based in Weight Reduction Among Obese Women Through 9‐Weeks Behavioral Weight Loss Program Geran Universiti Penyelidikan 241. Dr. Norma Abd Rahman Bond Strength of Orthodontic Brackets with two Adhesive Systems. Geran Jangka Pendek 242. Dr. Khaled Ali Othrub Comparing the Morbidity of External Laryngeal Nerve Injury in Thyroid Surgery With and Without Identifying The Nerve and Use of Neuromonitoring. 243. Dr. Ahmad Afifi Mohd Arshad Attenuation of Haemodynamic Respone During Intubation with Glidescope® Videolarynoscope Using Either Lignocaine or Magnesium; a Randomized Clinical Study. 244. Dr. Zainul Ahmad Rajion Evaluation of the Facial and Dental Arch Features in Malay Population. Geran Jangka Pendek 245. Dr. Daddy Suradi Halim Efficacy Between Local Honey and Bonjela for Treatment of Minor Recurrent Apthous Stomatitis. Geran Jangka Pendek 246. Prof. Madya Dr. Zurkurnai Yusof A phase 3 randomized, Double‐blind, Parallel‐group, Multi‐center Study of the safety and Efficacy of Apixaban for Prophylaxis of Venous Thromboembolism in Acutely III Medical Subjects During and Following Hospitalization Kajian Klinikal 247. Dr. Wan Shah Jihan Wan Din Efficacy of Ablution Nasal Washing in Reducing acute Respiratory Symptoms (ARS) among Male Hajj Pilgrims Geran Jangka Pendek | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | 235. Kelulusan Etika (Pelajar Sarjana Perubatan) Kelulusan Etika (Pelajar Sarjana Perubatan) 11 || LAPORAN TAHUNAN 2008 || 248. Dr. Wan Zaripah Wan Bakar In Vitro Evaluation of the Ferrule and Post Material on Failure load and Mode in Endodontically Treated Teeth. Geran Jangka Pendek 249. Dr. Jessina Sharis Othman A study on Oral Mucosal Lesions Among Adult Siamese Ethnic Group in Kelantan Kelulusan Etika (Pelajar Sarjana Perubatan) Mesyuarat ke 208 (24 Dis 2008) Bil Nama Penyelidik Tajuk Kategori Prof. Madya Dr. Shaiful Bahari Ismail A Pilot Study on the Quality of Life Among Patients With Androgen Deficiency (AD) Pre & Post Andriol Treatment Kelulusan Etika Sahaja 251. Prof .Madya Dr. Shaiful Bahari Ismail Study on the use of Tongkat Ali as Herbal Supplements for the Improvement of the Quality of Life & Sexual Wellbeing in Males Kajian Klinikal 252. Prof. Madya Pim Chau Dam The Effect of Iron Deficiency Anemia and Thalassemia and/ Hemoglobinopathy on Cognitive Function in Primary School Children Geran Universiti Penyelidikan 253. Dr. Ernie Haryantie Shaharudin A Study on The Effect of Normal Saline and Dextrose Saline Solution Infusion During Intrapartum 254. Dr. Mohd Nizam Md. Hashim Rapid Pleurodesis Using Small Bore Pigtail Catheter and Bleomycin In Malignant Pleural Effusions. 255. Dr. Salmi Ab. Razak Genetic Studies in Generalized Epilepsy. Geran Universiti Penyelidikan 256. Dr. Norzila Zakaria Anxiety, Depression and Female Sexual Dysfunction in Women Seeking Infertility Treatment Geran Jangka Pendek 257. Dr. Wan Azman Wan Sulaiman Linkage Analysis of the MSX1, TGF‐alpha, TGF‐beta and MTHFR in Non‐Syndromic Orofacial Cleft in Malay Population Geran FRGS 258. En. Wan Mohd Daud Wan Omar Prevalence of Muslim Patients Practising Daily Prayers in Medical Ward in Malaysia Government Hospitals. Kelulusan Etika Sahaja 259. Prof. Madya Dr. Zurkurnai Yusoff A Phase 3, Randomized, Double‐Blind, Double‐Dummy, Parallel Group, Multicenter, Multi‐National Study For Evaluation of Efficacy and Safety of DU‐176B versus warfarin in subjetcs with atrial fibrillation – Effective aNticoaGulation with Factor xA next Generation in Atrial Fibrillation (ENGAGE AF – TIMI 48). Kajian Klinikal 260. Prof.Madya Dr. Zurkurnai Yusoff A Randomized, Double‐ Blind, Placebo‐ Controlled, Event‐ Driven Multicenter Study to Evaluate the Efficacy and Safety of Rivaroxaban in Subjects With a Recent Acute Coronary Syndrome. Kajian Klinikal 261. Prof. Rahmah Noordin Molecular profiling of Toxoplasma gondii towards recombinant antigen and DNA‐based diagnostic for toxoplasmosis. Geran Universiti Penyelidikan 262. Dr. Mohd Suhaimi Abd Wahab A Retrospective Study to Assess the Clinical Burden of Community‐Acquired Pneumonia (CAP) and Invasive Pneumococcal Disease (IPD) Kajian Klinikal 263. Dr. Najwa Mansor A Study on Effect of IV Dexmedetomidine in Attenuating Haemodynamic Responses to Laryngoscopy and Intubation. Kelulusan Etika Sahaja 264. Dr. Tg. Muzaffar Tg. Mohamed Shihabudin The Outcome of Anterior Cruciate Ligament Reconstruction in Military Patients. Geran Universiti Penyelidikan 265. Dr. Ahmad Abir Ab. Ghani Childhood Atopic Dermatitis: Children Quality of Life and Family Impact. 266. Dr. Sasikumar A/L Rajagopal Percutaneus Nephrolithotripsy (PCNL) in HUSM: To Compare the Short term Clinical Outcome of Patients with Normal Impaired Renal Function. 267. Prof. D.r Ravindran Ankathil Genetic polymorphisms of inflammation response genes and their influence on colorectal cancer predisposition risk in Malaysian Population. Kelulusan Etika (Pelajar Sarjana Perubatan) Kelulusan Etika (Pelajar Sarjana Perubatan) Kelulusan Etika (Pelajar Sarjana Perubatan) Kelulusan Etika (Pelajar Sarjana Perubatan) Lampiran 1 ‐ Senarai Permohonan Dinilai Dalam Mesyuarat JEPeM Tahun 2008 250. Kelulusan Etika Sahaja | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | 12 || LAPORAN TAHUNAN 2008 || LAMPIRAN 2 SENARAI PEMEGANG GERAN JANGKA PENDEK USM TAHUN 2008 | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | 13 || LAPORAN TAHUNAN 2008 || Bil Nama Penyelidik Pusat Pengajian Dr. Mohd Asnizam Asari Pusat Pengajian Sains Perubatan 2 3 Tajuk Penyelidikan Tempoh Projek Nilai Geran Lulus (RM) Agihan 1 diterima (RM) 1 Mac 08 – 28 Feb 2010 13,934.00 13,934.00 Prof Madya Hasnan Jaafar Pusat Pengajian Sains Perubatan Expression of Bcl‐2 and Bax in Breast Cancer Cells and Its Blood Vessels and Their Association with Tumor Angiogenesis. 15 Mac 08 – 14 Mac 2010 31,908.00 19,108.00 Dr. Mohamad Hashim Mohd Hassan Pusat Pengajian Sains Perubatan Factors Influencing Late Booking Among Antenatal Mothers in Kota Bharu, Kelantan 15 Mac 08 – 14 Mac 2010 23,415.00 16,765.00 4 Dr. Wan Hazabbah Wan Hitam Pusat Pengajian Sains Perubatan A Study of Contrast Sensitivity and Quality of Life Following Phacoemulsification with 2 Different Types of Aspheric Lenses. 15 Mac 08 – 14 Mac 2010 26,200.00 26,200.00 5 Dr. Widowati Witjaksono Pusat Pengajian Sains Pergigian Effectiveness of Conventional Periodontal Maintenance with Tetracycline Irrigation Comparing to Scaling and Root Planing with Subgingival Minocycline. 15 Mac 08 – 14 Mac 2010 28,541.00 21,891.00 6 Dr. Shahrum Shamsuddin Pusat Pengajian Sains Kesihatan Mutational Analysis of Ras Gene Family in Oral Cancer using Denaturing High Performance Liquid Chromatography (dHPLC). 15 Mac 08 – 14 Mac 2010 26,710.00 18,700.00 7 Dr. Zainul Ahmad Rajion Pusat Pengajian Sains Pergigian The Development and Validation of Quality of Life Measurement for Children with Cleft Lip and/or Palate. 15 Mac 08 – 14 Mac 2010 14,796.00 4,070.00 8 Dr. Wan Norhaida Wan Abdullah Pusat Pengajian Sains Perubatan The Validation of the Malay Translated Attention Deficit Hyperactivity Disorder Rating Scale IV (ADHD RS IV) and Its Use in Determining the Prevalence of ADHD Among School Children Age 7 to 12 Years Old in Kota Bharu. 1 Mac 08 – 28 Feb 2010 9,065.00 5,330.00 9 Dr. Shatriah Ismail Pusat Pengajian Sains Perubatan A Study of an Association of Retinal Hard Exudates in Diabetic Exudative Maculopathy and Serum Lipids Among Type 2 Diabetic Patients in HUSM. 1 Mac 08 – 28 Feb 2010 18,184.00 18,184.00 10 Dr. Hafiza Arzuman Pusat Pengajian Sains Perubatan Relationship between Students’ Socio Economic Profile and Preadmission Academic Achievement to Their Academic Performance in MD Programme, Universiti Sains Malaysia 1 Mac 08 – 28 Feb 2010 9,542.00 3,972.00 11 Dr. Tengku Norbanee Tengku Hamzah Pusat Pengajian Sains Perubatan Work‐related Risk Factors of Carpal Tunnel Syndrome in Computer Users Among Clerical Staffs in Health Facilities, Kota Bharu, Kelantan. 1 Mac 08 – 28 Feb 2010 31,338.00 19,316.00 12 Dr. Che Badariah bt Ab. Aziz Pusat Pengajian Sains Perubatan Mutation Analysis of SMA Patients with Non‐deletion of The SMN Gene. 1 Mac 08 – 28 Feb 2010 19,939.00 18,620.00 13 Dr. Chen Chee Keong Pusat Pengajian Sains Perubatan Physiological Demands and Time Motion Analysis of Singles’ Badminton Play Following Implementation of 21 Point Scoring System. 1 Mac 08 – 28 Feb 2010 20,224.00 20,224.00 14 Prof. Madya Dr. Kamaliah Mohd Daud Pusat Pengajian Sains Perubatan Prevalence and Associated Factors for Microalbuminuria in Normotensive and Essential Hypertensive Patients. 1 Mac 08 – 28 Feb 2010 18,638.00 18,638.00 15 Dr. Ahmad Amir Ismail Pusat Pengajian Sains Perubatan Maximal Accumulated Oxygen Deficit (MAOD) for Physically Active Females During Mid‐Follicular and Mid‐Luteal Phases of Ovarian Cycle. 1 Mac 08 – 28 Feb 2010 22,129.00 11,064.00 16 Dr. Oleksandr Krasilshchikov Pusat Pengajian Sains Perubatan Effects of Various Jumping Exercises on Vertical Force Distribution and EMG Pattern in School Children. 1 Mac 08 – 28 Feb 2010 26,510.00 13,255.00 17 Dr Ahmad Helmy Abdul Karim Pusat Pengajian Sains Perubatan Study of Computed Tomography Perfusion in Traumatic Brain Contusion. 1 Mac 08 – 28 Feb 2010 38,565.00 35,260.00 18 Dr. Nik Munirah Nik Mahdi Pusat Pengajian Sains Perubatan 99m Tc‐MIBI Scintimammography in Diagnosing Breast Cancer, A Comparison with Mammography Findings. 1 Mac 08 – 28 Feb 2010 38,500.00 38,020.00 19 Dr. Emil Fazliq Mohd Pusat Pengajian Sains Perubatan Preliminary Study of Bone Densitometry Among Early Post Menopausal Women Mukim Tasek, Daerah Badang, Kota Bharu, Kelantan. 1 Mac 08 – 28 Feb 2010 23,000.00 11,500.00 20 Dr. Sam’an Malik Masudi Pusat Pengajian Sains Pergigian A Three‐Dimensional Noninvasive Assessment on Soft Tissue Facial Morphology in Malaysian Obese Populations in Relation with Cardiovascular Risk Factor. 1 Mac 08 – 28 Feb 2010 23,000.00 17,700.00 21 Dr. Asrenee Abdul Razak Pusat Pengajian Sains Perubatan A Preliminary Study on the Effectiveness of a Weight Management Behavioural Programme in Psychiatric Patients in HUSM. 1 Mac 08 – 28 Feb 2010 16,020.00 16,020.00 22 Dr. Wan Zaripah Wan Bakar Pusat Pengajian Sains Pergigian Fracture Resistant of Weakened Root Structure Reinforced by Two Types of Composite Resin and Endodontic Sealer. 1 Mac 08 – 28 Feb 2010 22,218.00 22,218.00 23 Dr. Zafarina Zainuddin. Pusat Pengajian Sains Kesihatan Screening and Characterization of 10398A Polymorphism in Invasive Breast Cancer in Malay Population of Peninsular Malaysia. 1 Mac 08 – 28 Feb 2010 29,879.00 16,170.00 24 Dr. Mohd Fadhli Khamis Pusat Pengajian Sains Pergigian The Efficacy of the Treatment with Reverse Twin Block and Chincup Appliances for Class III Malocclusion: A Randomized Clinical Trial. 1 Mac 08 – 28 Feb 2010 32,310.00 23,260.00 | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | Lampiran 2 ‐ Senarai Pemegang Geran Jangka Pendek USM 2008 Validity and Reliability of Rockport Fitness Walking Test (RFWT) Among Students University Sains Malaysia (USM) Health Campus. 1 14 || LAPORAN TAHUNAN 2008 || Bil Nama Penyelidik Pusat Pengajian Dr. Zaharah Sulaiman Pusat Pengajian Sains Perubatan 26 Tajuk Penyelidikan Tempoh Projek Nilai Geran Lulus (RM) Agihan 1 diterima (RM) 1 Mac 08 – 28 Feb 2010 24,750.00 24,750.00 Prof Madya Hillol Kanti Pal Pusat Pengajian Sains Perubatan Endonasal Endoscopic Cadaveric Dissection of Sellar‐suprasellar Region and Cavernous sinus ‐A Morphometric Study. 1 Mac 08 – 28 Feb 2010 33,400.00 23,400.00 27 Dr. Rajan Saini Pusat Pengajian Sains Pergigian Prevalence of Oral Mucosal Lesions in Diabetics and the Association between Diabetes and Oral Precancerous Lesions in HUSM Kota Bharu, Kelantan. 1 Mac 08 – 28 Feb 2010 18,314.00 18,314.00 28 Dr. Adibah Alawiah Hj. Abdul Razak Pusat Pengajian Sains Perubatan Effect of Continuous and Intermittent Exercise Training Programs on Fibrinolytic Profiles of Healthy Males. 15 Apr. 2008 – 14 Apr. 2010 24,807.00 13,360.00 29 Dr. Wan Zaidah Abdullah Pusat Pengajian Sains Perubatan Coagulation Factor XIII and Other Haemostatic Markers in Patients after Intra‐Cranial Surgery. 1 Mei 08 – 30 Apr. 2010 20,060.00 20,060.00 30 Dr. Adibah Hanim Ismail @ Daud Pusat Pengajian Sains Perubatan The Prevalence and Risk Factor of Sexual Dysfunction Among Women with Type 2 Diabetes mellitus in HUSM. 1 Mei 08 – 30 Apr. 2010 27,609.00 19,719.00 31 Dr. Norhayati Ludin Pusat Pengajian Sains Pergigian Microleakage in Class II Composite Restorations Bonded with Self‐etch, One‐step, One‐component Adhesive System. 1 Mei 08 – 30 Apr. 2010 25,450.00 16,450.00 32 Prof Madya Dr Hans Van Rostenberghe Pusat Pengajian Sains Perubatan The Effects of L‐Thyroxine on End Organ Damage in Asphyxiated Neonates. 1 Mei 08 – 30 Apr. 2010 17,400.00 17,400.00 33 Dr. Bal Kishan a/l Bhagat Ram Pusat Pengajian Sains Perubatan Effects of Isokinetic Resistance Training Program at Different Angular Velocities for Rehabilitation of Knee Osteoarthritis. 15 Mei 2008 – 14 Mei 2010 25,200.00 25,200.00 34 Dr. Nor Azwany Bt Yaacob Pusat Pengajian Sains Perubatan Risk Perception on Food Borne Diseases among Community in Kota Bharu, Kelantan. 1 Jun 2008 – 31 Mei 2010 16,216.00 7,776.00 35 Wan Soriany Wan Md Zain Pusat Pengajian Sains Perubatan Effect of Continuous and Intermittent Exercise Training Programs on Platelet Activation of Healthy Sedentary Males. 1 Jun 2008 – 31 Mei 2010 16,983.00 16,983.00 36 Dr. Mohd Nazri Shafei Pusat Pengajian Sains Perubatan Knowledge, Attitude and Practice (KAP) & Associated Factors for Leptopsirosis Among Workers of Kota Bharu Municipal Council (MPKB), Kelantan Malaysia. 15 Jun 2008 – 14 Jun 2010 35,038.00 23,978.00 37 Dr. Shaifulizan Abd.Rahman Pusat Pengajian Sains Pergigian The Comparison between The Effect of Flapless and Full‐thickness Flap Techniques on Crestal Bone Resorption and Osseointegration. 15 Jun 2008 – 14 Jun 2010 38,510.00 33,360.00 38 Prof Madya Dr. Shah Reza Johan Noor Pusat Pengajian Sains Perubatan Study on Red Blood Cell Alloantibodies Detection in Malay Women During Pregnancy. 1 Jun 2008 – 31 Mei 2010 27,548.00 20,088.00 39 Dr. Venkatesh R. Naik Pusat Pengajian Sains Perubatan Study of Neoangionesis and Profilerative Cell Marker in Colorectal Carcinoma. 1 Jun 2008 – 31 Mei 2010 24,300.00 10,150.00 40 Dr. Nik Hisamuddin Nik Ab. Rahman Pusat Pengajian Sains Perubatan Clinical Evaluation of 1‐Step Qualitative Heart‐Specific Fatty Acid Binding Protein (H‐FABP) Test (CardioDetect®) and Quantitative Cardiac Troponin T, for the Diagnosis of Acute Myocardial Infarction in the Emergency Department. 1 Jun 2008 – 31 Mei 2010 33,860.00 19,110.00 41 Dr. Azlina Ishak Pusat Pengajian Sains Perubatan Prevalence of Metabolic Syndrome (MS) among Polycystic Ovarian Syndrome (PCOS) Patients and its Associated Factor at Gynecology Clinic, HUSM. 1 Jun 2008 – 31 Mei 2010 21,970.00 13,750.00 42 Dr. Wan Nudri Wan Daud Pusat Pengajian Sains Perubatan Impact of Intensive Nutrition Education Program and Iron‐Folate Plus Vitamin C Supplementation on Iron Status and Cognitive Performance of Form Four Students in Rural Schools in Tanah Merah. 1 Jun 2008 – 31 Mei 2010 39,299.00 29,299.00 43 Cik Kasmah Wati Pardi Pusat Pengajian Sains Kesihatan Effectiveness of Online and Face‐to‐Face Problem‐Based Learning on the Performance of Diploma Nursing Students in A Nursing Course. 1 Jun 2008 – 31 Mei 2010 14,140.00 6,990.00 44 Dr. Yvone ‐ Tee Get Bee Pusat Pengajian Sains Kesihatan The Implication of Overweight on Microvascular Endothelial Function Assessed Using Iontophoresis‐Laser Doppler Fluximetry (IONTO+LDF) Measurement Model. 1 Jun 2008 – 31 Mei 2010 38,364.00 25,400.00 45 Dato' Prof. Mohamed Ghouse Nasuruddin Pusat Pengajian Seni Gamelan Music Therapy: Gross Motor Function in Children with Cerebral Palsy: A Pilot Study. 1 Dis 07 – 30 Nov. 2009 ‐ 15,654.00 46 Dr. Aravazhi Ananda Dorai Pusat Pengajian Sains Perubatan A Comparative Study of Honey Hydrogel with Safecare Hydrogel Dressing in the Treatment of Split Skin Graft Donor Sites. 1 Julai 08 – 30 Jun 2010 ‐ 10,300.00 47 Prof. Madya Dr. Nik Hazlina Nik Hussain Pusat Pengajian Sains Perubatan Prevalence of Metabolic Syndrome (MS) Among Postmenopausal Women Attending Gynaecology Clinic, HUSM. 1 Julai 08 – 30 Jun 2010 ‐ 20,150.00 48 Prof. Madya Dr. Wan Ahmad Kamil Wan Abdullah Pusat Pengajian Sains Perubatan Determinaion of Apparent Diffusion Coefficient of Blood at Its Various Age Using The Technique of Diffusion MRI. 1 Julai 08 – 30 Jun 2010 | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | 15,880.00 Lampiran 2 ‐ Senarai Pemegang Geran Jangka Pendek USM 2008 Validation of the Malay and Tamil Translated Women’s Health and Life Events Questionnaire. 25 10,780.00 15 || LAPORAN TAHUNAN 2008 || Bil Nama Penyelidik Tempoh Projek Nilai Geran Lulus (RM) Ultrasonography Measurement of Inferior Vena Cava Diameter of Blood Donors in HUSM Kelantan. 1 Ogos 2008 – 31 Julai 2010 26,220.00 20,570.00 21,020.00 15,050.00 Pusat Pengajian Tajuk Penyelidikan Agihan 1 diterima (RM) Pusat Pengajian Sains Perubatan 50 Dr. Norwati Daud Pusat Pengajian Sains Perubatan A Study on Obesity and Cardiovascular Risk Factors Among Male Soldiers in Melaka, Malaysia. 1 Ogos 2008 – 31 Julai 2010 51 Dr. Lee Yeong Yeh Pusat Pengajian Sains Perubatan The Prevalence and Associated Risk Factors of Clostridium difficile Infection in Patients with Diabetes Mellitus Treated with Antibiotic. 15 Ogos 2008 – 14 Ogos 2010 37,497.00 23,850.00 52 Dr. Hairul Anuar Hashim Pusat Pengajian Sains Perubatan The Effects of Two Relaxation Techniques on Physiological, Psychological and Psychomotor Variables During Repeated Maximal Intensity Activity Among School Athletes. 15 Ogos 2008 – 14 Ogos 2010 13,474.00 6,924.00 53 Dr. Julia Omar Pusat Pengajian Sains Perubatan Comparison of Serum Cystatin C with Creatinine Clearance and Estimated Glomerular Filtration Rate as a Marker for Detection of Early Renal Impairment on Type 2 diabetes mellitus patients. 15 Ogos 2008 – 14 Ogos 2010 32,405.00 26,505.00 54 Dr. Ma Saung Oo Pusat Pengajian Sains Perubatan Rectal Analgesia for Perineal Pain Relief After Childbirth: A Randomized Controlled Trial of Diclofenac Suppositories vs. Acetaminophen Suppositories. 15 Ogos 2008 – 14 Ogos 2010 18,220.00 12,370.00 55 Dr. Marini Ramli Pusat Pengajian Sains Perubatan Detection of Iron Deficiency Anaemia by Retic Haemoglobin (RET‐He) in Hemodialysis Patients on Erythropoietin (EPO). 1 Sept 2008 – 31 Ogos 2010 38,964.00 35,314.00 56 Dr. Mohd Suhaimi Abdul Wahab Pusat Pengajian Sains Perubatan Blood Lead Level Among Pediatric Thalassaemia Patients in Kota Bharu, Kelantan. 1 Sept 2008 – 31 Ogos 2010 25,006.00 18,650.00 57 Prof Madya Dr. Mohtar Ibrahim Pusat Pengajian Sains Perubatan The Role of the UVB Oxidative Damage in the Formation of Primary and Recurrent Pterygia Among Kelantan Population. 15 Sept. 2008 – 14 Sept 2010 13,095.00 7,835.00 58 Dr. Oleksandr Krasilshchikov Pusat Pengajian Sains Perubatan Effects of Progressive Combined Flexibility, Strength and Aerobic Exercise on Middle Aged Women with Early Stage Primary Knee Osteoarthritis. 1 Okt. 2008 – Sept. 2010 20,012.00 10,006.00 59 Dr. Juwita Syaaban Pusat Pengajian Sains Perubatan Validation of Malay Version of Rowland Universal Dementia Assessment Scale (Rudas) Among Elderly in Klinik Kesihatan Bandar Kota Bharu. 1 Okt. 2008 – Sept. 2010 15,438.00 9,788.00 60 En Che Ismail Che Lah Pusat Pengajian Sains Perubatan A Study of Mitochondrial A1555G Mutation in Aminoglycoside Induced Sensorineural Hearing Loss Patient. 15 Dis. 2008 – 14 Dis. 2010 34,810.00 29,494.00 61 Dr. Mohamed Saat Ismail Pusat Pengajian Sains Kesihatan Effects of Exercise Frequency on Hypercholesterolemic Male Individuals. 15 Nov. 2008 – 14 Nov. 2010 32,340.00 30,192.00 62 Dr. Mohd Yusof Sidek Pusat Pengajian Sains Perubatan Neurobehavioural Effects of Inorganic Lead Exposure in Battery Workers in Selangor. 15 Nov. 2008 – 14 Nov. 2010 18,790.00 9,395.00 63 Dr. Kamarul Aryffin Baharuddin Pusat Pengajian Sains Perubatan The Efficacy of Intravenous Parecoxib Sodium as An Analgesic Alternative to Morphine in Acute Trauma Pain: A Randomized Double Blinded Clinical Trial. 15 Nov. 2008 – 14 Nov. 2010 23,130.00 15,990.00 64 Dr Che’ Wan Aminud‐din Hashim Pusat Pengajian Sains Perubatan Features and Pathogens in Community Acquired Pneumonia (CAP). 15 Dis. 2008 – 14 Dis. 2010 29,600.00 14,800.00 1,503,684.00 1,158,573.00 JUMLAH Lampiran 2 ‐ Senarai Pemegang Geran Jangka Pendek USM 2008 Dr. Shaik Farid Abdull Wahab 49 | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | 16 || LAPORAN TAHUNAN 2008 || LAMPIRAN 3 SENARAI PEMEGANG GERAN PENYELIDIKAN UNIVERSITI TAHUN 2008 | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | 17 || LAPORAN TAHUNAN 2008 || Bil Penyelidik Tajuk Projek Kategori Che' Wan Aminuddin Hashim, Dr. Pusat Pengajian Sains Perubatan Safety an efficacy of Honey as A Supplementary Therapy for Chronic Obstructive Pulmonary Disease (COPD). Potential 2. Kirnpal Kaur Banga Singh, Dr. Pusat Pengajian Sains Perubatan Antibacterial Properties of Tualang Honey. Potential 3. Abu Dzarr Ganesh Abdullah, Dr. Pusat Pengajian Sains Perubatan An Open, Randomised, Controlled, Two Period cross‐over Study Comparing Honey to Ciprofloxacin as prophylaxis against febrile neutropenia in patients with Haematological malignanacy. Potential 4. Ab Aziz Al Safi Ismail, Prof. Madya Pusat Pengajian Sains Perubatan Metabolic Syndrome Study in Malaysia: The Prevalence and Risk Factors among Adolescent. Potential 5. Ahmad Sukari Halim, Prof. Pusat Pengajian Sains Perubatan In Vivo Evaluations of Angiogenic and Anti‐microbial Properties of Tualang Honey using a Full‐thickness Burn Wound on Animal Model. Potential 6. Ahmad Sukari Halim, Prof. Pusat Pengajian Sains Perubatan A Study On Microbiological and Angiogenic Properties of Burn Injuries Treated with Tualang Honey Versus Silver Based Dressing. Potential 7. Mohd Zaini Asmawi, Prof. Pusat Pengajian Sains Farmasi Pharmacological Evaluation Of Selected Products Available In The Community Pharmaacy Potential 8. Aishah Knight Abd Shatar, Dr. Institut Perubatan & Pergigian Termaju The Socio‐Economic Impact Of Breast Cancer On The Female Patients And Her Family in Penang And Kelantan Potential 9. Aishah Knight Abd Shatar, Dr. Institut Perubatan & Pergigian Termaju The Mapping Of Colorectal & Breast Cancer Cases With Reference To The Location Of Conventional Health Facilities Potential 10. T. P. Kannan, Dr. Pusat Pengajian Sains Pergigian Microsatellite Instability and Loss of Heterozygosity in Oral Squamous Cell Carcinoma in Malaysian Population Potential 11. Amutha Santhanam, Dr. INFORMM, Pulau Pinang. Immunoproteomics of Helicobacter Pylori Infaction In Different Gastric Pathologies: Towards The Identification Of Diagnostic Markers Potential 12. Azmi Sharriff, Prof. Madya Pusat Pengajian Sains Farmasi Implementing The Philosophy Of Pharmaceutical Care Into Community Pharmacy Services Potential 13. Baharudin Abdullah, Dr. Pusat Pengajian Sains Perubatan Epilepsy and Obstructive Sleep Apnea Syndrome (OSAS) 14. Biswa Mohan Biswal, Prof. Madya Pusat Pengajian Sains Perubatan Multicenter 3‐arm randomized control clinical trial comparing efficacy of topical honey‐alginate natural honey,versus best supportive care in the management of radiation mucositis among patients undergoing radical radiotheraphy for nasopharyngeal cancer Potential 15. Biswa Mohan Biswal, Prof. Madya Pusat Pengajian Sains Perubatan Phase‐II Clinical Trial Using Withania Somnifera (Ashwagandha) In The Prevention Of Chemotheraphy Induced Fatigue Among Breast Cancer Patients. Potential 16. Habsah Hasan, Dr. Pusat Pengajian Sains Perubatan Multifacted Approach Of Hospital Associated Infections Control Programme (MAHAICP) Towards Zero Tolerence HAI. Potential 17. M. Swamy, Dr. Pusat Pengajian Sains Perubatan Studies On Nitric Oxide (No), Citrulline‐No cycle Enzymes, Gultamine Synthetase And Oxidative Status In Epilepsy Rat Model Potential 18. Aida Hanum Ghulam Rasool, Prof. Madya Dr., Pusat Pengajian Sains Perubatan Pharmacological and Non Pharmacological Interventions Beneficial in Reducing Cardiovascular Risk in Obese Patients 19. Shariza Abdul Razak, Dr. Pusat Pengajian Sains Kesihatan Synthesis Of Biodegradable Times Release matrix From Plant Based Material For Antibiotic Delivery System. 20. Jafri Malin Abdullah, Prof. Pusat Pengajian Sains Perubatan The Potential Antieplleptic Bioactive Compounds Acting On GABA (A) Receptor from Myristice FragransH 21. K. N. S. Sirajudeen, Prof. Madya, Dr. Pusat Pengajian Sains Perubatan In Vitro Studies on the Antioxidant properties of Tualang Honey Potential 22. Zainal Ariffin Ahmad, Prof. Madya Pusat Pengajian Pengurusan EEG Biofeedback And Mental Health: An Integrative Agenda Potential 23. Wan Zaidah Abdullah, Dr. Pusat Pengajian Sains Perubatan A Comparative on Haemostatic Markers and Prothrombic Genes Among Patients With Acute Coronary Syndrome and Stable Ischaemic Heart Disease. Potential 24. Harmy Mohamed Yusoff, Dr. Pusat Pengajian Sains Perubatan Sub Optimization of Cardiovascular Screening Among apparently Healthy Post Menopausal Women in Malaysia. Potential | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | Fundamental Golden Goose Lampiran 3 ‐ Senarai Pemegang Geran Penyelidikan Universiti 2008 1. Potential Eureka 18 || LAPORAN TAHUNAN 2008 || Bil Penyelidik Tajuk Projek Kategori Siti Hawa Ali, Prof. Madya Dr. Pusat Pengajian Sains Perubatan Health Status and Health Impact Of Women Experiencing Violence (Domestic Violence) In Malaysia. Potential 26. Siti Amrah Sulaiman, Prof. Madya Dr. Pusat Pengajian Sains Perubatan Identification of Chemical Compound and Standardization of Madu Lebah Tualang Potential 27. Mohd Suhaimi Ab. Wahab, Dr. Pusat Pengajian Sains Perubatan Studies on the Antidiabetic and Antioxidant Effects of Local Tualang Honey in Streptozotocin‐Induced Diabetic Rats Potential 28. Nik Hazlina Nik Hussain, Prof. Madya Pusat Pengajian Sains Perubatan The Effects Of Tualang Honey On Peri‐Menopausal Women Potential 29. Ibrahim Shuib, Prof. Institut Perubatan & Pergigian Termaju Cholin Compound Quantification In determining Aggresiveness Of Maglinant Breast Disease Using Proton MR Spectoroscopy Potential 30. Narazah Mohd Yusoff, Prof. Madya Institut Perubatan & Pergigian Termaju Reliability Of N‐Terminal Pro‐B‐Type Natriuretic Peptide In The Diagnosis Of Congenital Heart Disease Potential 31. Ravindran Ankathil, Prof Pusat Pengajian Sains Perubatan Genome‐Wide Analysis OF The Allelic Imbalance In Sporadic Crc Among The Chinese In Malaysia (Terdahulu: Hoh Boon Peng, Dr.) 32. Amin Malik Shah Abdul Majid, Dr. Pusat Pengajian Sains Farmasi Pre‐Clinical Studies Of Standardized Extracts Of Orthosiphon Stanimeus (Os) And Strobilanthus Crispus (Sc) As Bio‐enhancers In The Treatment Of Breast And Colorectal Cancers 33. Noorizan H A Majid, Dr. Pusat Pengajian Sains Perubatan Susceptibility Of Helicobacter Pylori Infection, Among Kelantanese Population Potential 34. Dasmawati Mohamad, Dr. Pusat Pengajian Sains Pergigian Development of Aesthetic Dental Composites Based on Nanotechnology Potential 35. Harmy Mohamed Yusoff, Dr. Pusat Pengajian Sains Perubatan Sreening Of Colorectal Carcinoma Among Moderate Risk Patient Using Immunological Fecal Occult Blood In Kelantan. Potential 36. Radiah Yusoff, Dr. Pusat Pengajian Ilmu Kemanusiaan Pengubahsuaian pendekatan analisis perbualan HAVE (1999), WALKINSON (1999), dan BEEKE et al (2001) untuk menganalisis gangguan bahasa dalam kalangan pesakit kecederaan otak trauma (KOT) di USM. Potential 37. Rapeah Suppian, Dr. Pusat Pengajian Sains Perubatan The Potential Use Of Centella Asiatics As Anti‐Helicobacter Pylori Agent Potential 38. Rosline Hassan, Prof. Madya Dr. Pusat Pengajian Sains Perubatan Detection on Common Delectional Alpha‐Thallasaemia in Pregnant Lady by Polymerase Chain Reaction Potential 39. Rosline Hassan, Prof. Madya Dr. Pusat Pengajian Sains Perubatan Antitumour Effects Of Local Plants, Seeds and Honey on Human Leukemia Cell Lines and CML Induced Mice Model Potential 40. Ravindran Ankathil, Prof. Pusat Pengajian Sains Perubatan Influence of Genetic Variation of NFkB1A Geneotype in Sporadic Colorectal Cancer Susceptibility Risk Among 3 Ethic Population Subgroups of Malaysia Potential 41. Salmi Ab. Razak, Dr. Pusat Pengajian Sains Perubatan Genetic Studies In Generalised Epilepsi Potential 42. Salmi Ab. Razak, Dr. Pusat Pengajian Sains Perubatan Quality Of Life In Paediatric Epilepsy Children Potential 43. Mohd Iskandar Mohd Amin, Dr. Pusat Pengajian Sains Perubatan Comparative study of the effects of madu lebah tualang on healing of traumatic finger tip injury in comparison with paraffin gauze dressing Potential 44. Abdul Nawfar Sadagatullah, Dr. Pusat Pengajian Sains Perubatan Honey Dressing as a means of Granulation Tissue Promoter for Wounds in Patients With Diabetic Foot Ulcers Potential 45. Siti Amrah Sulaiman, Prof. Madya Dr. Pusat Pengajian Sains Perubatan Development of Medicated Honey Spray and Gel for Burn and Diabetic Wounds Dressing Potential 46. Siti Amrah Sulaiman, Prof. Madya Dr. Pusat Pengajian Sains Perubatan Study to Evaluate the Potential of Madu Lebah Tualang in Parventing the Development of Breast and Colon Cancer in Animal Models Potential 47. Mohamed Azmi Ahmad Hassali, Dr. Pusat Pengajian Sains Farmasi Population ‐ Based study On The Non‐Prescription Medicine Utilization In The Community Setting Potential 48. Foo Leng Huat, Dr. Pusat Pengajian Sains Kesihatan A Study of Determinants of Bone Health in Adolescent Boys and Girls in Kelantan Potential | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | Potential Golden Goose Lampiran 3 ‐ Senarai Pemegang Geran Penyelidikan Universiti 2008 25. 19 || LAPORAN TAHUNAN 2008 || Bil Penyelidik Tajuk Projek Kategori Wan Abdul Manan Wan Muda, Prof. Pusat Pengajian Sains Kesihatan Wellness Integrated Project For Community Well Being Potential 50. Wan Nazirah Wan Yusuf, Dr. Pusat Pengajian Sains Perubatan Study of the Effects of Madu Lebah Tualang on Asymptomatic HIV Patients Potential 51. Wan Shah Jihan Wan Din, Dr. Pusat Pengajian Sains Perubatan The effects of Tualang Honey Ingestion on IgE and Symptoms score in patients with allergic rhinitis Potential 52. Wan Zuraida Wan Ab. Hamid, Dr. Pusat Pengajian Sains Perubatan A Study Of Lymphocyte Subset In Epileptic Patients Potential 53. Win Mar@Salmah, Dr. Pusat Pengajian Sains Perubatan Normative Data For Hippocampal And Temporal Lobe Volume In Normal Malay Population Potential 54. Zabidi Azhar Husin@ Mohd Hussin, Prof. Pusat Pengajian Sains Perubatan Mapping Of Children with Malnutrition In Kelantan Utilizing Open Source Geographic Information System (GIS) And Remote Sensing Platform Potential 55. Kamaliah Mohd. Daud, Prof. Madya Pusat Pengajian Sains Perubatan The Effects of adjuvant honey theraphy on disease activity T and B lymphocyte function and lymphocyte subset in patient with Systemic Lupus Erythematosus (SLE) Potential 56. Zalina Ismail, Prof. Pusat Pengajian Sains Kesihatan Cognitive Reserve In The Modulation Of Learning And Memory: A Fundamental, Clinical And Community‐Based Wellness Programme 57. Zarina Zainan Abidin, Dr. Pusat Pengajian Sains Perubatan Honey as a Supplementary Therapy for Patients with Depression Potential 58. Zhari Ismail, Prof. Pusat Pengajian Sains Farmasi Analysis Content In Marketed Products Available in The Community Pharmacy Registered As OTC (MAL00000X) and TCM (MAL 00000T) Products (Nutraceuticals and Herbals) Potential Golden Goose Lampiran 3 ‐ Senarai Pemegang Geran Penyelidikan Universiti 2008 49. | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | 20 || LAPORAN TAHUNAN 2008 || LAMPIRAN 4 SENARAI OUTPUT PENYELIDIKAN | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | 21 || LAPORAN TAHUNAN 2008 || SUMBER MANUSIA OUTPUT BIL PENYELIDIK TAJUK PROJEK TERBITAN JURNAL M. Sc Ph. D Dr. Win Mar Kyi Paraoxonase 1Gln/Arg 192 Polymorphism in Three Ethnic Groups in Malaysia. 1. Normy Normaizam Ab Hana, Hasenan Nordin, Faridah Abdul rashid, Mohd Rafi Mustapha and Win Mar Kyi. Paraoxonase 1 Gln/Arg 192 polymorphism among three ethnic groups in Malaysia. 1st National Conference on Medical Laboratory Sciences. 7‐9th Nov. 2006 [Oral presentation]. 1. Normy Normaizam Ab Hana, Hasenan Nordin, Faridah Abdul Rashid, Mohd Rafi Mustapha and Win Mar Kyi. Paraoxonase 1 Gln/Arg 192 polymorphism and lipid profile among three ethnic groups in Malaysia. 1 2 Dr. Nizam Abdullah Risk Factors For High Caries Experience Among 16 Year Old School Children in Tumpat District, Kelantan. 1. Wan Salina, A. Nizam, L. Naing. A Study on the prevalence of high caries among 16 year old school children in Tumpat, Kelantan. 10th National Conference on Medical Sciences, USM 21‐22 May 2005. 1. Wan Salina, A. Nizam, L. Naing. The Association of birth order and socioeconomic factors with severity of caries experience among adolescents in Tumpat. Archives of Oral Biology. 2. Wan Salina, A. Nizam, L. Naing. Oral health knowledge, attitude and practice among 16 year old school children in Tumpat. 4th Kelantan Public Health Conference, USM 5‐7 July 2005. 3. Wan Salina, A. Nizam, L. Naing. Level of saliva mutans streptococci and lactobacilli in high caries group of 16 year old school chldrenin Tumpat. 4th Kelantan Public Health Conference, USM 5‐7 July 2005. 1 3 Dr. Adibah Ibrahim A Study of Bacterial Vaginosis in HUSM – Towards a Standard Diagnostic Method. 1. Azura H, Adibah I, Fauziah I, Rosliza AR, Siti Suraiya MN. Study of demographic factors in Kelantanese Pregnant Women in bacterial vaginosis. 2nd.National Conference in Infectious Diseases: Immunocompromised Host: Challenges in Management, Grand Riverview, Kota Bharu, Kelantan, 14‐15 Feb. 2007.[Oral peresentation] 2. Azura H, Adibah I, Fauziah I, Rosliza AR, Siti Suraiya MN. Evaluation of the Nugent's criteria and the Amsel's criteria in the diagnosis of bacterial vaginosis. PPSP, 2006.[Oral peresentation] 1. Azura H, Adibah I, Fauziah I, Rosliza AR, Siti Suraiya MN. A Study of Bacterial Vaginosis in HUSM – Towards a Standard Diagnostic Method. Singapore Medical Journal. 1 4 Dr. Gan Siew Hua Genetic Polymorphisms of CYP3A4 & CYP2C8 in Healthy Volunteers Administered with Repaglinide. 1. A.B. Ruzilawati*, A.W. Mohd Suhaimi, S.H. Gan. Genetic polymorphisms of CYP3A4: CYP3A4*18 allele is found in five healthy Malaysian subjects.PubMed 2007; 383:158‐162. 5 Dr. Widowati Witjaksono Sealing Ability of Hydroxyapatite as a Root Canal Sealer : In Vitro Study. 1. Widowati Witjaksono, Lin Naing, ema Mulyawati, AR Samsudin, Mon Mon Tin Oo. Sealing Ability of hydroxyapatite as a root canal sealer: in vitro study. Dental Journal 2007; Vol 4, No.3, Sept. 2007: 101‐105. 6 Dr. Habsah Hasan Comparison of 2 Biochemical Tests for Identification of Enterobacteriaceae in Clinical Isolates in HUSM 1. Habsah H., Nabilah I. (2007). Identification of Enterobacteriaceae by Conventional Biochemical Test, Enterotube II and Analytical Profile Index 20E. 4 th Asia Pacific Conference in Risk Management for Preventive Medicine, Crown Princess Hotel, Kuala Lumpur, 20‐22 Nov. 2007, Awarded 2nd Best Poster Presentation.[Poster Presentation]. 2. Habsah H., Nabilah I. (2007). Comparison of two biochemical tests for Identification of Enterobacteriaceae in clinical Isolates in HUSM. 2nd. National Conference on Infectious Disease, Grand River View Hotel, Kota Bharu, Kelantan, 14‐15 February 2007, [Oral Presentation]. 1. Habsah H., Nabilah I. (2008). Comparison of two biochemical tests for Identification of Enterobacteriaceae in clinical Isolates in Tertiary‐teaching Hospital in Malaysia. 1 7 Prof. Madya Arunodaya Barman Students’ Learning Style of School of Medical Sciences, Universiti Sains Malaysia. 1. Arunodaya Barman, Rogayah Jaafar. Medical Students' Learning Styles in Universiti Sains Malaysia. Med‐Ed.Online, 2008. 8 Dr. Gan Siew Hua Stereoisomer Concentrations of Amphetamine, Amphetamine Derivatives and Metabolites in Saliva and Urine in Comparison with Blood Plasma Levels Utilizing A Validated Stereoselective Gas Chromatography Ion‐trap Mass Spectrometry Assay. 1. Wan Raihana W.A., Tan S. C and Gan S.H. A Rapid Method for Sterospecific Analysis of Amphetamine‐type Stimulants using Simultaneous Liquid‐liquid Extraction and Chiral Derivatization. 10th European Regional ISSX Meeting, Vienna, Austria, 18‐21 May 2008. 1. Wan Raihana W.A., Tan S. C and Gan S.H. The Application of A Screening Experimental Design to Identify Parameters Influencing the Extraction and Chiral Derivatization of Amphetamine‐type Stimulants. 3rd Mathematicl and Physical Sciences Graduate Congress, Universiti Malaya, 12‐14 Dec. 2007. 9 Dr. Abdullah Pohchi Hydroxyapatite‐based materials as replacement material : in vivo study. 1. A. Pohchi, A.H. Suzina, A.R. Samsudin, K.A. Al‐Salihi. Comparative Study between dense and porous hydroxyapatite using light and scanning electron microscopy. Med. Journal Malaysia, 59, p.151‐152, 2004. bone | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | Lampiran 4 ‐ Output Penyelidikan 2008 PEMBENTANGAN 1 22 || LAPORAN TAHUNAN 2008 || SUMBER MANUSIA OUTPUT BIL PENYELIDIK TAJUK PROJEK TERBITAN JURNAL M. Sc Ph. D Dr Tengku Norbanee Tengku Hamzah Pregnancy Spacing and Fetal Risk: Associated Factors, Knowledge and Attitude. 1. Tg Alina TI. Prevalence and factors associated with contraception use among Malay women at HUSM. 5th National Conference, 25‐26 July 2007, PPSG, USM.[best presenter‐oral presentation]. 2. Tg Alina TI. Knowledge attitude on family planning among Malay women and their husbands in Kota Bharu, Kelantan. Second Asia Pacific Conference on Public Health, 3‐5 July 2007, Sheraton, Subang.[best presenter‐oral presentation]. 3. Tg Alina TI. Contraception use among Malay postnatal mothers at HUSM prior to the current pregnancy. 21st Scientific Meeting of the Malaysian society of Pharmacology and Physiology, 25 April 2006, Grand River view Hotel Kota Bharu. [oral presentation]. 1. Alina TI., Norbanee TH., Hashim MH., Zaki NM. Knowledge on Family planning among Malay women who delivered at Hospital Universiti Sains Malaysia (HUSM), Kelantan and their husbands. Malaysian J. of Public Health Medicine, vol. 6(2):68‐ 71, 2006. 2. Alina TI., Norbanee TH., Hashim MH., Zaki NM. Prevalence and factors associated with short birth spacing among Malay women in Kota Bharu. International Medical J.2 Apr. 2007. 1 11 Dr Bal Kishan Bhagat Ram Expression of IG‐1R in Human Osteosarcoma. 1. Bal Kishan, Zulm Wan. Expression of Insulin‐like growth factor‐1 receptor (IG‐1R) in Human Osteosarcoma. Annual Scientific Meeting, 23‐25 May 2003, Kota Bharu. [2nd place ‐oral presentations]. 12 Dr. Asia Rehman (PPSG) Studies to Investigate the Prevalence of Estrogen Receptor Polymorphism & its Association with Alveolar Bone Loss & Early Tooth Loss in Postmenopausal Women. [Geran Jangka Pendek] 1. ERG Polymorphisms & Alveolar Bone Loss in Postmenopausal Malay Women. 20th Scientific Meeting of International Association of Dental Research, 1‐4 Sept. 2005 [Poster presentation]. 2. Estrogen Receptor Genotypes & Alveolar Bone Loss in Postmenopausal Malay Women. Europerio 5, Madrid, Spain. 26th June ‐ 1st July, 2006 [Poster presentation]. 13 Dr. Asia Rehman (PPSG) Studies to Investigate the Role Genetic Polymorphism of Renin Angiotensin Aldosterone System in the Etiology & Pathogenesis of Hypertensive & Diabetic Vascular Disease. 1. Dzuzaini M. Bhazali, Asia Rehman, Abdul Rashid A. R. Candidate Gene Polymorphisms and Their Association with Hypertension in Malays. ScienceDirect, 388:46‐50, 2008. 14 Dr. Wan Norlida Ibrahim Cost Effectiveness Study of Managing Type 2 Diabetics in Two Different Types of Primary Care in Kelantan. 1. Rohana D., Zawiah D., Wnorlida WI., Nor Azwany Y., Mazlan A.. Quality Indicators in Management of Type 2 Diabetes at Primary Care Lavel. Journal of Community Health (suppl1): 11, 2006. 2. Rohana D., Zawiah D., WNorlida WI., Nor Azwany Y., Mazlan A.. Economic Evaluation of Type 2 Diabetic Management at Primay Care Level. Malaysian Journal of Public Health, vol. 7, 2006. 3. Rohana D., Zawiah D., WNorlida WI., Nor Azwany Y., Mazlan A., CheKamalusin CM., Che Ghani CS. Economic Evaluation of Type 2 Diabetes Management at The Malaysian Ministry of Health Primay Care in Machang, Kelantan. Malaysian Journal of Public Health, vol. 7(1), 2007. 1 15 Dr. Che Badariah Abdul Aziz The Effects of “Gamat” on Nociceptive Processing in The Central Nervous System. 1. Abdul Aziz CB., Siti Fatehah A., Mohd Khairul Azizi A., Asma Hayati A., Zalina I., Mohsin SJJ. The Effects of gamat on pain behaviour in Acute Inflammatory pain model. International Medical & Health Congress 2007, 25‐28 Mei 2007. 2. Abdul Aziz CB., Haron MN., Mohd Eidham Y., Siti Fatehah A., Mohd Khairul Azizi A., Asma Hayati A., Zalina I., Mohsin SJJ. The Effects of Intraperitoneal Administration of gamat extracts on nociceptive responses in the formalin injected rats. MSPP 22nd Scientific Meeting, 5‐6 April 2008. 3. Abdul Aziz CB., Haron MN., Mohd Eidham Y., Siti Fatehah A., Mohd Khairul Azizi A., Asma Hayati A., Zalina I., Mohsin SJJ. The Effects of Gamat Extracts on Pain Behaviour and C‐Fos Expression in the formalin injected rats. 13th national Conference on Medical Sciences, 2008. 16 Dr. Wan Rosli Wan Ishak Sensory Qualities and Physico‐chemical Characteristics of Beef and Chicken Burger Incorporated with Zea mays Hairs. 1. Nurhanan AR., wan Rosli WI., Mohsin SSJ. Preliminary Chemical Analysis of Zea mays Hairs. 2nd Health & Medical Sciences Conferences 2008, Pulau Pinang, 19‐20 Jun 2008. | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | 1. Taib H, Swaminathan D, Rehman A., Abdllah N., Ahmad A. Estrogen Receptor Gene Polymorphisms in Alveolar bone Resorption Among Selected Postmenopausal Malay Women. Annals of Dentistry vol. 12:52, 2006. 2. Taib H, Swaminathan D and Rehman A et. Al. Estrogen Receptor Genotypes & Alveolar Bone Loss in Postmenopausal Malay Women. Journal od Clinical Periodontology, vol. 33, suppl. 7: 149‐150, 2006. Lampiran 4 ‐ Output Penyelidikan 2008 PEMBENTANGAN 10 23 || LAPORAN TAHUNAN 2008 || SUMBER MANUSIA OUTPUT BIL PENYELIDIK PEMBENTANGAN TERBITAN JURNAL M. Sc Ph. D 17 Dr. Nurul Khaiza Yahya Th1 and Th2 Cytokine Profile in Women with Unexplained Infertility. 1. WAH Wan Zuraida, Y Nurul Khaiza, NH Nik Hazlina. Comparing mean or Th1(IL 12 and IFNg) and Th2 (IL 4 and IL 13) Cytokine Profile in A Case of Unexplained Infertility in Kota Bharu, Kelantan. 5th National Health Conference, 25‐26 July, 2007.[Oral presentation] 1. WAH Wan Zuraida, Y Nurul Khaiza, NH Nik Hazlina. Th1 and Th2 Cytokine Profile in A Case of Unexplained Infertility in Kota Bharu, Kelantan. Malaysian Journal of Medical Sciences, Vol. 14 Suppl 1, 2007. 1 18 Dr. Aziah Daud An Intervention Study to Improve the Knowledge, Attitude and Practice Related to Noise Induced Hearing Loss Among Sawmill Workers. 1. Razman MR, Naing L., Aziah BD., Kamarul Imran M. The Related factors on Noise Reduced Hearing Loss Among Sawmill Workers in Kota Bharu, Kelantan: Focus Group Discussion. 4th Asia Pacific on Risk Management for Preventive Medicine, 20‐22 Nov. 2007. Malaysian Journal of Public Health Medicine, vol.7 (suppl. 3) 2007. [Poster Presentation]. 2. Razman MR, Naing L., Aziah BD., Kamarul Imran M. Reliability and Construct Validity of Noise‐Induced Hearing Loss Questionnaire: Preliminary Results of the Validation Study. 4th Asia Pacific on Risk Management for Preventive Medicine, 20‐22 Nov. 2007. Malaysian Journal of Public Health Medicine, vol.7 (suppl. 3) 2007. [Poster Presentation]. 19 Dr. Bakiah Shaharuddin A Study on Optic Disc Parameters Among Malay Students in Health Campus, USM by Helderberg Retinal Tomograph II. 1. S. Bakiah, J Shawarinin and WH Wan hazabbah. Optic Disc Parameters among Malay Students of Health Campus, USM by Heidelberg Retinal Tomograph II. 2nd Penang Post Graduate International Convention:Health & Medical Sciences Conference. 18‐20 June, 2008. [Poster presentation]. 20 Dr. Kaneez Fatima Amla A Study of TGFA Gene Polymorphism in Non‐ Syndromic Cleft Lip with or Without Cleft Palate. 1. Mutations in the TGF Alpha Gene in Non‐Syndromic Cleft Lip with or Without Cleft palate Patients in Malaysia. 13th National Conference on Medical Sciences, 22‐23 May 2008. [Oral Presentation]. 21 Dr. Che Badariah Abdul Aziz The Effects of “Gamat” on Nociceptive Processing in The Central Nervous System. 1. Abdul Aziz CB., Haron MN., Mohd Eidham Y., Siti Fatehah A., Mohd Khairul Azizi A., Asma Hayati A., Zalina I., Mohsin SSJ. The Effects of Intraperitoneal Administration of gamat extracts on nociceptive responen in the formalin injected rats. 22nd MSPP Scientific Meeting 2008.[Poster presentation] 1. Abdul Aziz CB, Siti Fatehah A., Mohd Khairul Azizi A., Asma hayati A., Zalina I., Mohsin SSJ. The Effects of gamat on Pain Behaviour in Acute Inflammatory Pain Model. The Malaysian Journal of Medical Sciences, Vol. 14(suppl.) 2007. 2. Che Badariah AA., Haron MN, Mohd Eidham Y., Siti Fatehah A., Mohd Khairul Azizi A., Asma Hayati A., Zalina I., Mohsin SSJ. The Effects of Gamat Extracts on Pain Behaviour and C‐fos Expression in the Formalin Injected Rats. The Malaysian Journal of Medical Sciences, Vol. 15(suppl.) 2008. 22 Dr. Mohd Suhaimi Ab Wahab Pharmacokinetics Interactions Between Propranolol and Herbal Products (Tongkat Ali). 1. Shima'a Ahmad ben‐salman, Siti Amrah S., Mohd Suhaimi AW., Gan SH., Zabidah I., Azimahtol Hawariah LP., Rolsi I., Chan KL., Yuen KH. A Pharmacokinetic Interaction Between Propranolol and Eurycoma longifolia (Tongkat ali) extract. The Malaysia Journal of Medical Sciences, Vol. 14(suppl.) 2007.[Poster Presentation]. 1. Shima'a Ahmad ben‐salman, Siti Amrah S., Mohd Suhaimi AW., Gan SH., Zabidah I., Rosli I., Chan KL., Yuen KH. Pharmacokinetic Interaction Between Propranolol and Eurycoma longifolia water‐base extract. Journal of Clinical Pharmacy and Biomedical Analysis. 2. Shima'a Ahmad ben‐salman, Siti Amrah S., Mohd Suhaimi AW., Gan SH., Zabidah I., Rosli I., Chan KL., Yuen KH. HPLC Method validaion for the Detection of Propranolol in Human Plasma. Journal of Clinical Pharmacy and Therapeutics. 1 Dr. Gan Siew Hua Genetic Polymorphisms of CYP3A4 & CYP2C8 in Healthy Volunteers Administered with Repaglinide. 1. Ruzilawati AB., Mohd Suhaimi AW., Gan SH. Genetic polymirphisms of CYP3A4 in Healthy Malaysian Subjects. 7th National Congress on Genetics, Renaissance Hotel, Kota Bharu kelantan., 5‐7 May 2007. [Oral presentation]. 2. Ruzilawati AB., Mohd Suhaimi AW., Gan SH. CYP2C8 Genotyping among healthy subjects in Malaysia. 7th National Congress on Genetics, Renaissance Hotel, Kota Bharu kelantan., 5‐7 May 2007. [Poster presentation]. 3. Ruzilawati AB., Mohd Suhaimi AW., Gan SH. Effects of CYP3A4*18 on repaglinide's pharmacokinetics. 10th European International Society fot the study of Xenobiotics (ISSX), Vienna, Austria, 18‐21 may 2008. [Poster presentation]. 1. Ruzilawati AB., Mohd Suhaimi AW., Gan SH. Genetic polymorphisms of CYP3A4*18allele is found in five healthy Malaysian subjects. Clinica Chimica Acta 383: 158‐162, 2006. [Hadiah sanjungan USM 2007, publication category: impact factor 2.328] 2. Ruzilawati AB., Mohd Suhaimi AW., Gan SH. Effects of CYP3A4*18 on repaglinide's pharmacokinetics. Drugs metabolism review, vol. 40(suppl. 1), 2008. [Impact factor 6.238] 3. Ruzilawati AB., Mohd Suhaimi AW., Gan SH. Population pharmacokinetics modelling of repaglinide in healthy subjects by using NPAG algorithm. Journal of Clinical Pharmacy and Therapeutics. 1 23 1. Identification of novel haplotypes in the k‐primer region of TGF Alpha Gene in non‐syndromic cleft lip with or without cleft palate patients in Malaysia.The Cleft Palate‐Craniofacial Journal.2008. Lampiran 4 ‐ Output Penyelidikan 2008 TAJUK PROJEK | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | 24 || LAPORAN TAHUNAN 2008 || SUMBER MANUSIA OUTPUT PENYELIDIK PEMBENTANGAN TERBITAN JURNAL M. Sc Ph. D 24 Dr. Bakiah Shaharuddin A Study on the Capability of Frequency Doubling Perimetry in the Detection of Visual Field Abnormalities in Primary Open Angle Glaucoma Patients. 1. Nor Fadzillah AJ., Bakiah S., Wan Hazabbah WH. Detection of visual field abnormalities using humphrey matrix frequency doubling perimetry among poag patients. 23rd Malysia ‐ Singapore Opthalmic Congerss, Kota Kinabalu, Sabah; 1 ‐ June 2007.[Poster Presentation] 2. Nor Fadzillah AJ., Bakiah S., Wan Hazabbah WH. The Use of humphrey matrix frequency doubling perimetry versus humphrey visual field analyzer among poag patients. 23rd Malysia ‐ Singapore Opthalmic Congerss, Kota Kinabalu, Sabah; 1 ‐ June 2007.[Poster Presentation] 3. Nor Fadzillah AJ., Bakiah S., Wan Hazabbah WH., Zunaina E., Shatriah I. Sensitvity and specificity of humphrey matrix frequency doubling perimetry in the detection of visual field abnormalities among poag patients. 23rd Malysia ‐ Singapore Opthalmic Congerss, Kota Kinabalu, Sabah; 1 ‐ June 2007.[Poster Presentation] 4. Nor Fadzillah AJ., Bakiah S., Wan Hazabbah WH. Visual field abnormalities detection by frequency doubling perimetry versus humphrey field analyzer in primary open angle glaucoma. World Glaucoma Congress, Singapore, 18‐ 21 July, 2007.[Poster Presentation] 5. Nor Fadzillah AJ., Bakiah S. A Study on the capability of frequency doubling perimetry in the detection of visual field abnormalities in primary open angle glaucoma patients. Asia‐Arvo Meeting on research in Vision and Opthalmology, 2‐5 March, 2007. [Poster Presentation] 1. Nor fadzillah AJ., Bakiah S. A Study on the Capability of Frequency Doubling Perimetry in the Detection of visual Field Abnormalities in Primary Open Angle Glaucoma Patients. Asian Journal of Opthalmology, 9(suppl): p.129, 2007. 2. Nor Fadzillah AJ., Bakiah S., wan Hazabbah WH. Clinical use of FDT SS2 staging system in the detection of visual field abnormalities in primary Open Angle Glaucoma. Journal of Glaucoma (submitted), 2008. 1 25 Prof. Madya Noorizan Abd Aziz Knowledge, Attitude and Practice (KAP) on the Prevention of Respiratory Tract Infections Among Malaysian Hajj Pilgrims. 1. Sarab M Mansor., Noorizan Abdul Aziz, Yahaya Hassan, Hasnah hashim, Aishah Knights Abd Shatar, Nor Hayati Othman, Abdullah talib, Abdul Razak Mutallif. Knowledge, Attitude and Practice in Prevention of Respiratory Tract Infections and Antibiotic Usage Among Malaysian Hajj Pilgrims. Asean Scientific Conference in Pharmaceutical Technology, The Bay View Beach Resort, Pulau Pinang, 1‐3 June 2008. 2. Sarab M Mansor., Noorizan Abdul Aziz, Yahaya Hassan, Hasnah Hashim, Aishah Knights Abd Shatar, Abdullah Talib. Data Base on Upper Respiratory Tract Infections Among Malaysian Hajj Pilgrims of 2008. 2nd national Seminar on Hajj Best Practices through Advances & Technology. Eureka Complex, Penang. 28‐30 July 2008. 3. Sarab M Mansor., Noorizan Abdul Aziz, Yahaya Hassan, Hasnah Hashim, Aishah Knights Abd Shatar, Abdullah Talib. Do knowledge, attitude and practice have an Impact on the severity of the Upper Respiratory Tract Infections in Malaysian Hajj Pilgrims. 2nd national Seminar on Hajj Best Practices through Advances & Technology. Eureka Complex, Penang. 28‐30 July 2008. 1 26 Dr. Che Badariah bt Ab. Aziz Mutation Analysis of SMA Patients with Non‐ deletion of The SMN Gene. 1. Fatemah H., Watihayati MS., Marini M., Atif AB., Che Badariah AB Aziz, Zilfalil BA. Mutation Analysis of the non‐deleted samples of survival neuroni in spinal muscular atrophy patients. Medical Genetic Conference 16‐19 Nov. 2007. [Poster presentation]. 2. Fatemah H., Watihayati MS., Marini M., Atif AB., Che Badariah AB Aziz, Zilfalil BA. Ethical issues relating to molecular genetic testing of spinal muscular atrophy. The International Congress of Medical Ethics in Iran, 16‐ 18 April 2008. [Poster presentation]. 1. Fatemah H., Watihayati MS., Marini M., Atif AB., Che Badariah AB Aziz, Zilfalil BA. Molecular analysis test of survival motor neuron gene in 118 Malaysian spinal muscular atrophy (SMA) patients. Malaysian Journal of Medical Sciences, vol. 15(suppl. 1) 2008. TAJUK PROJEK Lampiran 4 ‐ Output Penyelidikan 2008 BIL | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | 25 || LAPORAN TAHUNAN 2008 || SUMBER MANUSIA OUTPUT BIL PENYELIDIK TAJUK PROJEK TERBITAN JURNAL M. Sc Ph. D Dr. Sam’an Malik Masudi In Vitro Evaluation of Sealing Ability of A New Nano‐Hydroxyapatite Endodontic Sealant. 1. SM Masudi, N Luddin, D. Mohamad, JJ Alshakshir, R Adnan, RA Ramli. In vitro study on apical sealing ability of nanohydroxyapatite‐filled epoxy resin based edodontic sealer. International Conference on Advancement of materials and nanotechnology: innovative research into the 21st century, 29 May ‐ 1 June 2007, Langkawi Kedah. [Oral presentation and Published in proceedings]. 2. SMA Alomari, Z Ab Ghani, A Husein, SM Masudi. The coronal sealing ability of a novel nano hydroxyapatite‐filled endodontic sealer. 15th Scientific meeting of FDI world dental federation and MDA, 25‐27 Jan 2008, K. Lumpur. [oral presentation] 3. SM Masudi, R Adnan, AA Ramli. Histological analysis of nano hydroxyapatite root canal sealer. 8th World Biomaterial Congress 2008, 28 May ‐ 1 June, 2008, Amsterdam, Netherlands. [oral presentation] 4. SM Masudi. An In vitro study on dentina closure of nano hydroxyapatite and micro crystalline hydroxyapatite. Scientific forum in dentistry, University of Trisakti, Jakarta; 6‐9 July 2005. [oral presentation] 1. SM Masudi, AR Samsudin, R Adnan, RA Ramli. Perbandingan efek hidroksiapatit berukuran nano dan hidroksiapatit standar terhadp penutupan tubuli dentin secara in vitro. Indonesian Scientific Journal in dentistry, 20:61, July 2005. [Publication]. 2. SM Masudi, N Luddin, D Mohamad, R Adnan, RA Ramli. In vitro study on apical sealing ability of nano hydroxyapatite‐filled epoxy resin based endodontic sealer. Dentalmaterials, Elsevier Journal. [in progerss‐publication]. 3. SM Masudi, AR Ismail, AR Samsudin, R Adnan, NS Omar. Silver Award ‐ exhibit product :nanoseal, novel root canal sealer. International Expoxition of Research and Invention of Institutions of Higher Learning 2007 (PECIPTA) 10‐12 August 2007, KLCC. [product] 4 28 Prof. Madya Asok Kumar Ghosh The Effect of Sago‐Soy Protein Supplementation on Endurance Cycling Performance in a Thermoneutral Environment. 1. Asok Kumar Ghosh, A. Abdul Rahaman and Rabindarjeet Singh. Combination of Sago and Soy Protein Supplementation during Endurance Cycling Exercise Can Improve Subsequent High Intensity Endurance Capacity. International Journal of Sports Nutrition, 2008. 1 29 Dr. V. K. Gopinath Prof. Mustaffa Musa The Effect of hydroxyapatite on the function of murine macrophage in vitro.[Geran IRPA EA: 06‐ 02‐05‐00029 EAR] 1. RA Ramli, R Adnan, S. Masudi, M Abu Bakar. Preparation and characterization of hydroxyapatite‐chitosan nanocomposites by blending process. 1st International Postgradute Convention, 24‐27 May 2006, USM Penang. [Oral presentation and Published in proceedings]. 1. Gopinath VK., Musa M., samsudin AR., Lalitha P., Sosroseno W. Role of nitric oxide in hydroxyapatite‐induced phagocytosis by murine macrophage cell line. Archive Oral Biology 51, 339‐344 2006. 2. Gopinath VK., Musa M., Samsudin AR., AKM Al Salihi., Sosroseno W. Hydroxyapatite‐induced phagocytic activity by murine macrophages in vitro. American journal biochemical and biotech. 2(3): 85‐88, 2006. 3. Gopinath VK., Musa M., Samsudin AR., Sosroseno W. Role of Protein Kinace C in hydroxyapatite induced phagocytosis in cells. Immunopharmacology and Immunotoxicology, 28(3): 485‐9, 2006.. 2(3): 85‐88, 2006. 4. Gopinath VK., Musa M., Samsudin AR., Sosroseno W. Role of IL‐B and TNF‐alpha on HA‐ induced phagocytosis by murine macrophage cells lines. British Journal of Biomedical Sciences, 36 (4): 176‐178, 2006. 30 Prof. Rusli Nordin A Study of Neurobehavioural Performances Among Car Spray Painters Exposed to Environmental Lead in Kota Bharu, Kelantan. 1. Mohd Nazhari MN. Neurobehavioural Performances Among Car Spray Painters and Car Mechanics Exposed to Environmental Lead in Kota Bharu, Kelantan. Malaysian Journal of Health Medicine. Vol. 5 (suppl. 1) 2005. 2. Mohd Nazhari MN. Burden of Lead Toxicity ot Car Spray Painting and Service Premises in Kota Bharu, Kelantan. Journal of Community Health. Suppl.1, 2006. 1 31 Dr. Norsa’adah Bachok Delay in Seeking Diagnosis and Treatment Among Women with Breast Cancer. 1. Nor'sadah B., Krishna Gopal R., Rahmah MA., Tengku Norbanee TH., Nyi Nyi Naing, Biswa B. Delay in Consultation and Diagnosis of Breast Cancer in East Coast Malaysia. The Malaysian Journal of Medical Sciences, vol 15, suppl. 1, 2008 32 Dr. Siti Noor Fazliah Mohd Noor Dental Age in Malay Population in Kelantan Based on Demirjian’s Method. 1. SH Abu Asab, S. Mohd Noor, MF Khamis. Radiographic Dental Age in Kelantanese Malay Children. 14th Malaysian Association of Orthodontists (MAO) Scientific Conference & Trade Exhibition,Pronce Hotel, K. Lumpur. 27‐28 Apr. 2008. Lampiran 4 ‐ Output Penyelidikan 2008 PEMBENTANGAN 27 | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | 26 || LAPORAN TAHUNAN 2008 || SUMBER MANUSIA OUTPUT BIL PENYELIDIK TAJUK PROJEK PEMBENTANGAN TERBITAN JURNAL M. Sc Ph. D Dr. Mohd Khairi Md. Daud A Study on The GJB3 and GJB6 Gene Mutations Among Malays with Non‐Syndromic Hearing Loss. 1. Z Siti Aishah, MD Mohd Khairi, AR Normastura, Z Zafarina, BA Zilfalil. Screening of Gap Junction Protein Beta‐2 Gene Mutations in Malays with Autosomal Recessive, Non‐syndromic Hearing Loss, Using Denaturing High Performance Liquid Chromatography. The Journal of Laryngology & Otology, 1 of 5, 2008. 34 Dr. Gan Siew Hua Stereoisomer Concentrations of Amphetamine, Amphetamine Derivatives and Metabolites in Saliva and Urine in Comparison with Blood Plasma Levels Utilizing A Validated Stereoselective Gas Chromatography Ion‐trap Mass Spectrometry Assay. 1. WR Aan Aasim, SH Gan and SC Tan. Development of a simultaneous liquid‐liquid extraction and chiral derivatization method for stereospecific GC‐MS analysis of amphetamine‐type stimulants in human urine using fractional factorial design. Prof. Dr. Syed Mohsin Syed Sahil Jamalulail A Study of The Pattern of Usage of Traditional Herbs Over The Pregnancy Period Among Kelantanese Malay Pregnant Women. 1. Law KS, Soon LK, Farid CG & Syed Mohsin, SSJ. Prevalence of Herbal Usage Among The Kelantanese Malay Women Over The Pregnancy Period. The 13th National Conference Medical Sciences pada 22‐23 May 2008 di Kampus Kesihatan, USM, Kelantan. 2. Law KS, Soon LK, Syed Mohsin, SSJ & Farid CGhazali.Sanggul Fatimah (Anastatica Hierochuntica L.): Ultra‐Structural Finding and Suggestion Of Its Medicinal Properties, 17th Electron Microscopy Society of Malaysia (EMSM) Scientific Conference & 18th Annual General Meeting pada 18‐20 December 2008 di Hotel Everly Resort, Melaka. 36 Dr. Gan Siew Hua Stereoisomer Concentrations of Amphetamine, Amphetamine Derivatives and Metabolites in Saliva and Urine in Comparison with Blood Plasma Levels Utilizing A Validated Stereoselective Gas Chromatography Ion‐trap Mass Spectrometry Assay. 1. Wan Raihana W.A., Tan S. C and Gan S.H. Development of a stimultaneous liquid‐ liquid extraction and chiral derivatization method for stereospecific GC‐MS analysis of Amphetamine‐type Stimulants in Human Urine using Fraztional Factoial Design. Biomedical Chromatography, 22: 1035‐1042 (2008). 37 Dr. Rapiaah Mustaffa Detection of Human Platelet‐Specific Antigens Among Regular Blood Donors in HUSM. 1. Azly Sumanty, Rapiaah M, Rosline H, Selamah G, Narishah S. Gene Frequencies of Human Platelet Specific Antigen (HPA‐1) in Malay and Chinese Blood Donors in Malaysia. The 3rd. National Transfusion Medicine Conference 2007, Berjaya Times Square Hotel & Conventional Centre, K. Lumpur. 1. Azly Sumanty, Rapiaah M, Rosline H, Selamah G, Narishah S. Gene Frequencies of Human Platelet Specific Antigen (HPA‐1) in Malay and Chinese Blood Donors in Malaysia. The 4th Transfusion Medicine Course for Arabic Speaking Countries. Sarjah, UAE, 11‐13 Dec. 2007. 38 Dr. Aziah Daud An Intervention Study to Improve the Knowledge, Attitude and Practice Related to Noise Induced Hearing Loss Among Sawmill Workers. 1. Razman MR, naing L., Aziah BD, Kamarul Imran M. The Related Factors on Noise Induce Hearing Loss Among Sawmill Workers in Kota Bharu, Kelantan:Focused Group Discussion.Malaysan Journal of Public Health Medicine. Vol 7(suppl. 3 ) 2007. [Presented at 4th Asia Pacific Conference on risk managemen for Preventive Medicine 2007.] 2. Razman MR, Naing L., Aziah BD, Kamarul Imran M. Realiability and Construct Validity Loss Questionnaire: Preliminary Results of the Validation Study..Malaysan Journal of Public Health Medicine. Vol 7(suppl. 3) 2007. [Presented at 4th Asia Pacific Conference on risk managemen for Preventive Medicine 2007.] 1. Aziah Daud. Validation of noise induced hearing loss questionnaire among sawmill workers in Kelantan, Malaysia. Singapore Medical Journal, 2008. 2. Aziah Daud. Knowledge, Attitude and Practice of Sawmill workers in Kota Bharu, Kelantan towards noise induced hearing loss. [submitted for publication] 39 Dr. Mohamad Ikram Ilias A Randomised Controlled Trial of Parenteral Glutamine in Newborn Receiving Total Parenteral Nutrition (TPN) in HUSM. 1. Mohamad Ikram I, Quah BS, Noraida R, Stanislaus D, Faris I, Rostenberghe HV. A Randomised Controlled Trial of Parental Glutamine in Newborn Receiving Total Parenteral Nutrition (TPN) inHospital USM. The Malaysian Journal of Medical Sciences, Vol. 15, Suppl. 1, 2008..[2nd National Aediatric Research Conference In Conjunction With UMMC Paediatric Liver Update; Faculty of Medicine University of Malaya 27‐28 March 2008] Best Oral Presentation 40 Dr. Sam’an Malik Masudi A Three‐Dimensional Noninvasive Assessment on Soft Tissue Facial Morphology in Malaysian Obese Populations in Relation with Cardiovascular Risk Factor. 1. Silver Award at the 19th International Invention, Innovation & Technology Exhibition ITEX 2008 in Application of Photogrammetic Camera System in Medical Imaging. 1. S.M. Masudi, A.A.S. Ismail, Z.A. Rajion, N. Sukminingrum. A Three‐Dimensional Noninvasive Assessment on Soft Tissue Facial Morphology in Malaysian Obese Populations in Relation with Cardiovascular Risk Factor. International Journal of Obesity. 35 Lampiran 4 ‐ Output Penyelidikan 2008 33 | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | 27 || LAPORAN TAHUNAN 2008 || SUMBER MANUSIA OUTPUT PENYELIDIK TAJUK PROJEK 41 Dr. Norkhafizah Saddki Survival and Prognostic Factors of Oral Cancer Patients in Hospital Universiti Sains Malaysia. 42 Prof Madya Dr. M. Ravichandran Endoscopic Findings and Evaluation of Molecular Method in Detecting Fungal Etiology in Chronic Rhinosinusitis. 43 Dr. Mohd Nazri Shafei Knowledge, Attitude and Practice (KAP) & Associated Factors for Leptopsirosis Among Workers of Kota Bharu Municipal Council (MPKB), Kelantan Malaysia. PEMBENTANGAN TERBITAN JURNAL M. Sc Ph. D 1. Co‐morbidity and Habits effects on survival of oral cancer in HUSM. International Medical & Health Congress 25‐28 May 2007 [Oral] 2. Socio‐demography characteristics and survival of oral cancer in HUSM. International Medical & Health Congress 25‐28 May 2007 [Poster] 3. Smoking and oral cancer in HUSM. Second Asia Pacific Conference on Public Health, 3‐5 July 2007, Sheraton Subang Hotel and Tower, Subang, Kuala Lumpur [Oral] 4. Impact of Oral cancer stage on patients’ survival in HUSM. Second Asia Pacific Conference on Public Health, 3‐5 July 2007, Sheraton Subang Hotel, Kuala Lumpur [Oral] 5. Impact of Oral cancer treatment on patients survival in HUSM. Fifth National Health Conference, 25‐26 July 2007, PPSG, USM [Oral] 6. Oral Cancer profile in HUSM. Fifth National Health Conference, 25‐26 July 2007 PPSG, USM. [Best Poster presentation – Second place] 7. Survival and prognosis factors of oral cancer in HUSM. Asia Pacific Conference on Risk Management and Preventive Medicine, 20‐22 Nov. 2007, Crown Princess Hotel, KL. [Best Poster presentation – First place] 8. Trends of oral cancer over twenty years in HUSM: 1986‐2005. Asia Pacific Conference on Risk Management and Preventive Medicine, 20‐22 Nov. 2007, Crown Princess Hotel, KL. [Poster] 9. Factors associated with advanced stage of oral cancer in HUSM. Asia Pacific Conference on Risk Management and Preventive Medicine, 20‐22 Nov. 2007, Crown Princess Hotel, KL. [Oral] 10. Presentation of oral squamous cell carcinoma among patients in Hospital Universiti Sains Malaysia. 13th National Conference on Medical Sciences, 22‐23 May 2008, PPSP, USM. [Poster] 11. Influence of age on the survival of oral cancer patients in Hospital th Universiti Sains Malaysia. 13 National Conference on Medical Sciences, 22‐ 23 May 2008, PPSP, USM. [Poster] 12. Survival of oral cancer patients in HUSM over twenty years. Oral Health Research Conference, 30 July‐1 August 2008, Kuala Lumpur. [Poster] 1. Shahrul H., Ravichandran M., Shamim AK. Endoscopic Findings and Evaluation of Molecular Method in Detecting Fungal Etiology in Chronic Rhinosinusitis. 27th International Symposium of Infections & Allergy of Nose. 1‐4th Merch 2007. 1. Co‐Morbidity and habits effects on survival of oral cancer in HUSM. The Malaysian Journal of Medical Sciences, Vol 14 (Supplement 1), p.96 Socio‐demographic characteristics and survival of oral cancer in HUSM. The Malaysian Journal of Medical Sciences, Vol 14 (Supplement 1), p.211 2. Smoking and oral cancer in HUSM. Malaysian Journal of Public Health Medicine, Vol 7 (Supplement 2), p.36. 3. Impact of oral cancer stage on patients’ survival in HUSM. Malaysian Journal of Public Health Medicine, Vol 7 (Supplement 2), p.47 Influence of age on the survival of oral cancer patients in HUSM. The Malaysian Journal of Medical Sciences, Vol 15 (Supplement 1), p.169. Survival of oral cancer patients in Hospital Universiti Sains Malaysia, Kelantan. Oral Oncology. 4. Prognostic factors of oral cancer patients in a tertiary hospital in Kelantan. Oral Diseases. 1 1. Mohd Rahim S., Mohd Nazri S., YN Azwany, Habsah H. Seroprevalence of Leptospirosis among town service workers in Kota Bharu, Kelantan. The 40th Conference of Asia pacific Academic Consortium for Public Health.Universiti Malaya, 7‐9 Nov. 2008. 1. Mohd Rahim S., Mohd Nazri S., YN Azwany, Habsah H., Aziah BD., Zahiruddin WM., Zaliha I., Mohamed Rusli A. Reliability and Construct Validity of Knowledge, Attitude and Practice Questionnaire on Leptospirosis. 3rd Regional Conference on Occupational health; Malaysian Journal of Public Health Medicine Vol. 8 (supp. 1) 2008. Lampiran 4 ‐ Output Penyelidikan 2008 BIL | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | 28 || LAPORAN TAHUNAN 2008 || SUMBER MANUSIA OUTPUT BIL PENYELIDIK TAJUK PROJEK PEMBENTANGAN 45 Dr. Adibah Hanim Ismail@Daud Dr. Biswa Mohan Biswal Use of HbA1c in the Diagnosis of Diabetes in High Risk Group Attending Outpatient Clinic (KRK), HUSM. Comparative Phase‐II Study of Conventional Fractionated Radiotherapy Plus Brachytherapy versus Continuous Hyperfractionated Accelerated Radiotherapy (CHART) and Brachytherapy in Locally Advanced Cervical Cancer. [06‐02‐05‐103 7 PR 0024/09‐07] TERBITAN JURNAL 1. Adibah Hamin Ismail, Hasni Ibrahim, Shaiful Bahari Ismail, Wan Mohamad Wan Bebakar. Use of HbA 1C in The Diagnosis of Diabetes mellitus Type 2 in High Risk Partient Attending Outpatient Clinic (KRK) HUSM. 10th Malaysian Family Medicine Specialist Scientific Conference, 12‐15 July 2006, Perak. 2. Adibah Hamin Ismail, Hasni Ibrahim, Shaiful Bahari Ismail, Wan Mohamad Wan Bebakar. The use of HbA 1C in The Diagnosis of Diabetes mellitus Type 2 in High Risk Partient Attending Outpatient Clinic (KRK) HUSM. 18th WONCA World Conference, 24‐27 July 2007, Singapore. 3. Adibah Hamin Ismail, Hasni Ibrahim, Shaiful Bahari Ismail, Wan Mohamad Wan Bebakar. The use of HbA 1C in The Diagnosis of Diabetes mellitus Type 2 in High Risk Partient Attending Outpatient Clinic (KRK) HUSM. The 2005 Congress of the Asean Federation of Endocrine Societies Dec 2005, Philippines. 1. BM Biswal, N Ahmad, ZA hanafiah, a Zakaria, NH Othman. Preliminary study comparing 10 days continuous hyperfractionated accelerated radiotherapy (CHART) versus conventional radiotherapy in conjuction with HDR brachytherapy in locally advanced cervical cancer.International Journal of Radiation Oncology Biology Physics.[Oral] M. Sc 1 1. BM Biswal, N Ahmad, ZA hanafiah, a Zakaria, NH Othman. Phase II Prospective, non randomized clinical trial, comparing standard fractionated radiotherapy (CHART) versus 10 day continuous hyperfractionated accelerated with high dose rate (HDR) brachytherapy in locally advanced cervical cancer.International Journal of Radiation Gynecological Cancer, 2008. [Oral] Ph. D Lampiran 4 ‐ Output Penyelidikan 2008 44 | PELANTAR PENYELIDIKAN SAINS KLINIKAL, USM | 29