Duke University Eliminates Animal Labs in Medical Teaching PCRM
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Good Medicine From the Physicians Committee for Responsible Medicine / Summer 2007 / Vol. XVI, No. 3 Duke University Eliminates Animal Labs in Medical Teaching PCRM Complaint Halts Misleading Dairy Advertisements European Union Approves New Tests, Spares More Than 250,000 Animals Don’t Forget Your Vitamin B12 Help End Dissection in Local Schools PCRM Celebrates the Art of Compassion ® Editorial Drug Dependency A nother medication is suspected of having life-threatening side effects and may soon be pulled from the market. Avandia, the trade name for GlaxoSmithKline’s diabetes drug rosiglitazone, was reported in the New England Journal of Medicine to increase heart attack risk by 43 percent. The analysis was conducted by Steven Nissen and Kathy Wolski of the Cleveland Clinic and compiled the results of 42 prior studies. In its defense, the manufacturer cited other studies that showed no increased risk. And no one has yet nailed down the mechanism by which Avandia would damage the heart, although possibilities include its tendency to boost low density lipoprotein (“bad”) cholesterol (by an average of 19 percent), precipitate congestive heart failure, and reduce blood counts. For now, Avandia remains on the market. Avandia is the latest in a long series of drugs that have turned out to present serious potential risks. Just last December, Pfizer pulled the plug on torcetrapib, a drug that was supposed to raise high density lipoprotein (“good”) cholesterol, but was associated with unexpected deaths in human tests. Premarin, used for “hormone replacement,” increases the risk of heart disease, cancer, and stroke. The painkiller Vioxx caused thousands of deaths from heart attacks and strokes. All these cases have left public health officials and journalists wringing their hands, wondering what we can do if drugs let us down. The first answer, of course, is to focus on the causes of illness. No clinician believes that type 2 diabetes is caused by a rosiglitazone deficiency. Rather, it is largely the result of diet and lifestyle. Although genes play a role in susceptibility, the meaty, fatty Western diet is strongly associated with whether the disease manifests or not. Similarly, genes influence heart disease risk one way or another. A person who avoids tobacco and animal products and remains physically active has a strong measure of protection. Some doctors are pessimistic about the benefits of diet changes, because conventional diets have been disappointing. However, going a step further—eliminating Avandia is the latest in a animal products, minimizing oils, and avoiding sugar and other high-glycemic-index foods—is dramatically more effective. Moreover, the “side effects” of vegetarian and long series of drugs that vegan diets are all good ones. In addition to helping control diabetes, they also trim have turned out to present waistlines, cut cholesterol, and lower blood pressure. serious potential risks. This does not mean that there is no role for medication. But most patients treated with medications have never had the benefit of a really good diet that might have prevented their condition or made it more manageable. So why are blockbuster drugs presenting unforeseen risks? Two reasons: First, drug companies now focus on products for long-term use. Rather than eking out profits from antibiotics used for a week or two or vaccines administered just once, they are investing in drugs designed to become a permanent part of your life. So toxicities that might not show up over the short run may well add up as the years go by. Second, drug companies continue to rely on animal tests, which often fail to show the dangers faced by human patients. Newer test methods that can more accurately predict the results in patients will mean safer medications. And when diet changes are used to their full effect, medications may be needed much less frequently. GOOD MEDICINE Summer Summer 2007 2007 Harry Giglio Neal D. Barnard, M.D. President of PCRM Good Medicine® From the Physicians Committee for Responsible Medicine Summer 2007 Vol. XVI, No. 3 Contents Contents Editor in Chief Neal D. Barnard, M.D. Managing Editor/Designer Doug Hall Editor Margaret Southern Associate Editor Patrick Sullivan Contributing Writer Sarah Farr Production Manager Lynne Crane Web Designer Lisa Schulz aDVISORY bOARD T. Colin Campbell, Ph.D. Cornell University Caldwell B. Esselstyn, Jr., M.D. The Cleveland Clinic Suzanne Havala Hobbs, Dr.P.H., M.S., R.D. University of North Carolina–Chapel Hill Henry J. Heimlich, M.D., Sc.D. The Heimlich Institute Lawrence Kushi, Sc.D. Kaiser Permanente John McDougall, M.D. McDougall Program Virginia Messina, M.P.H., R.D. Nutrition Matters, Inc. Milton Mills, M.D. Gilead Medical Group Myriam Parham, R.D., L.D., C.D.E. East Pasco Medical Center William Roberts, M.D. Baylor Cardiovascular Institute Andrew Weil, M.D. University of Arizona Affiliations are listed for identification only. PCRM STAFF • Aysha Akhtar, M.D., M.P.H. Senior Medical and Research Adviser • Kyle Ash Legislative Coordinator • Jonathan Balcombe, Ph.D. Senior Research Scientist • Nancy Beck, Ph.D. Research Analyst • Robin Bernstein Legal Fellow • Simon Chaitowitz Senior Communications Specialist • Cael Croft Associate Designer • Claudia Delman, M.P.H. Outreach Manager • Jill Eckart Assistant to the President • Tara Failey Communications Coordinator • Sarah Farr Writer/Information Officer • Allison George Research Program Coordinator • Claire Gregory, Esq. Associate General Counsel • Patricia Howard Advertising and PSA Manager • Mark Kennedy, Esq. Attorney • Dan Kinburn, Esq. General Counsel • Susan Levin, M.S., R.D. Dietitian • Lynn Maurer Associate Designer • Jeanne Stuart McVey Media Relations Manager • Ryan Merkley Research Program Coordinator • April Meyer Legal Assistant • Melanie Miller Research Program Assistant • John Pippin, M.D. Senior Medical and Research Adviser • Deborah Press Legal Intern • Chad Sandusky, Ph.D. Director of Toxicology and Research • Ximena Savitch Nutrition and Research Assistant • Edith Sodolo Communications Coordinator • Patty Slowik Nutrition Program Coordinator and Physician Liaison • Margaret Southern Web Editor/Staff Writer • Kristie Stoick, M.P.H. Scientific and Policy Advisor • Patrick Sullivan Director of Communications • Caroline Trapp, M.S.N., C.N.P., B.C.-ADM, C.D.E. Director of Diabetes Education and Care • Marie Warner Communications Assistant • Laura Yin Research Program Coordinator • Boris Zdravkovic Administrative Assistant • THE CANCER PROJECT • Jennifer Anthony Nutrition Intern • Njambi Gibson Marketing Intern • Kathy Glisson Director of Marketing • Chelsea Lenge, R.D. Dietitian • Lauray MacElhern Managing Director • Michelle Rohner Outreach Program Coordinator • PCRM FOUNDATION • Nabila Abdulwahab Data Processor • Milosz Banbor Accounting Manager • Melinda Beard Receptionist • Mary Brumfield Accounts Payable Accountant • Deniz Corcoran Data Entry Manager • Sossena Dagne Data Processor • George Dawson Web Developer • Joey Doubek Accounting Assistant • Will Flores Technology Specialist • Brian Halprin Membership Coordinator • Katerina Herodotou Development Assistant • Stephen Kane Finance Director • JohnR Llewellyn Internet Marketing Manager • Debbi Miller Special Events Manager • Leroy Perez Director of Technology • Tekola Pettis Literature Manager • Bethany Richmond Human Resources Coordinator • Betsy Wason, C.F.R.E. Director of Development • Rod Weaver Data Manager • Gregory Wright Facilities Manager • Stacey Ziegenhein Human Resources Manager • Craig Ziskin Associate Director of Annual Giving • WASHINGTON CENTER FOR CLINICAL RESEARCH • Hope Ferdowsian, M.D., M.P.H. Director of Clinical Research • Valerie Hoover Clinical Research Coordinator • Lady Ung Clinical Research and Nutrition Intern • CONSULTANTS • Jarrod Bailey, Ph.D. • Shawna Benston • Susan Berkow, M.D. • Shawna Broida • Megha Even, M.S. • Amber Green, R.D. • Peggy Hilden • Brent Jaster, M.D. • Amy Lanou, Ph.D. • Paul Marcone • David Nash, M.D. • Tim Radak, Dr.P.H., M.P.H. • Jennifer Raymond • Jennifer Reilly, R.D. • Garrett Strang • Dulcie Ward, R.D. Good Medicine is published quarterly by the Physicians Committee for Responsible Medicine,5100 Wisconsin Ave.,NW,Suite 400,Washington, DC 20016, tel 202-686-2210, fax 202-686-2216. It is distributed as a membership benefit to PCRM members. Basic annual membership in PCRM is $20 (tax-deductible). PCRM promotes good nutrition, preventive medicine, ethical research practices, and compassionate medical policy. Readers are welcome to reprint articles without additional permission. Please include the credit line: Reprinted from Good Medicine, Summer 2007, Physicians Committee for Responsible Medicine. Articles are not to be reprinted for resale. Please contact PCRM at [email protected] regarding other permissions. ©PCRM 2007. Good Medicine is not intended as individual medical advice. Persons with medical conditions or who are taking medications should discuss any diet and lifestyle changes with their health professional. “Good Medicine” is a registered trademark of the Physicians Committee for Responsible Medicine.“Physicans Committee for Responsible Medicine,”“PCRM,”“The Cancer Project,” “Humane Charity Seal,” and “The Gold Plan” are trademarks of PCRM, federal registration pending. www.PCRM.org printed on recycled paper 6 10 11 14 23 Art of Compassion Weekend 6 PCRM Celebrates the Art of Compassion 7 Gala-Goers Treated to a Full Day of Good Health 8 PCRM Recognizes Compassion and Innovation in Awards Ceremony Research Issues 9 Duke University Eliminates Animal Labs in Medical Teaching 6 Pushing the March of Dimes Toward Compassionate Research 10 New Approved Tests to Spare More Than 250,000 Animals in European Union Send a Free Dissection E-Card Action Alert: Help End Dissection in Local Schools Nutrition and Prevention 11 Success Stories: Tackling Diabetes with Simple Diet Changes 14 Meet Caroline Trapp, M.S.N., A.P.R.N., B.C.-ADM, C.D.E. Don’t Forget Your Vitamin B12 15 PCRM’s Complaint Halts Misleading Dairy Advertisements The Cancer Project 16 The Cancer Project Update 17 The News You Need Departments 4 The Latest in... 18 Member Support The Art of Compassion Gala / Kim Howe—A Strong Voice for PCRM 20 PCRM Marketplace 23 Just the Facts 24 Physician Profile Gordon Saxe, M.D., Ph.D.: Innovative Research on Diet and Prostate Cancer Cover Background: istockPHOTO PCRM Phone Extensions 202-686-2210 Health Charities and Research Issues..........................................ext. 335 Literature Requests....................................................................ext. 306 ........................................................................................ext. 316 Media. Membership (change of address, duplicate mailings, renewal questions)..................................................ext. 304 Nutrition....................................................................................ext. 395 PCRM Doctors and laypersons working together for compassionate and effective medical practice, research, and health promotion. Summer 2007 GOOD MEDICINE The Latest in… The Latest in… Research Ethics By Kristie Stoick, M.P.H., and John J. Pippin, M.D., F.A.C.C. ALTERNATIVES TO ANIMAL RESEARCH Relief on the Way for Chronic Wound Healing Research P P harmaceutical companies often use animals not only to test new drugs but also to test the inactive ingredients that go into their products. Excipients, as they are called, are often the same from one company to the next. But because competing companies do not share their test data, the same compounds are tested on animals again and again. This spring, however, a major initiative has been launched to create a proprietary data repository for the test results of excipients. U.K.-based simulation organization Lhasa Ltd. has brought together 10 pharmaceutical companies and devised a way to safeguard each company’s data while constructing a searchable, referable toxicity database that can be used instead of animal tests. Lhasa Limited in collaboration project to drive further reduction in the need for animal testing. Available at: http://www.lhasalimited. org/index.php?cat=6&sub_cat=6#15. Accessed May 14, 2007. Progress in Hepatic Modeling: A Pioneering Initiative ore than a dozen experts at the University College London have pooled their expertise in computer sciences, physiology, child health, and chemical engineering to work on a monumental GOOD MEDICINE MEDICINE Winter Summer 2007 GOOD 2006 UCL Beacon Project Web site. Available at: http://grid.ucl.ac.uk/biobeacon/php/index.php?id=frontpage. Accessed May 11, 2007. Dr Hadwen Trust Press Release. March 12, 2007. Animal experimenters often use pigs for wound healing research. © istockphoto M project: a working computer model of the human liver. The UCL Beacon project seeks to allow the study of important liver diseases, such as diabetes or cirrhosis, as well as other liver functions, such as the metabolism of chemicals or drugs. The project is extraordinarily complex, but it is a promising step toward more ethical and effective research, especially when combined with the latest news about in vitro liver tissue models (see Good Medicine, “The Latest In” column, Spring 2007). © istockphoto Groundbreaking Database Project Set to Cut Animal Testing CRM has often spoken out against wound research using animals. This research usually involves the intentional infliction of severe or catastrophic wounds on animals in order to test a potential therapy, or deliberately infecting an animal’s wounds to prevent healing. Now, scientists, led by Dr. Phil Stephens of Cardiff University in the United Kingdom, are developing a research model that can help determine factors behind chronic wound diseases without the use of animals. Funded by the Dr Hadwen Trust, Dr. Stephens uses tissues donated by human patients and genetic techniques to determine molecular factors behind differences between healthy and ulcerated tissue. Dr. Stephens said, “We hope that the development of this laboratory model will be an important and unique resource for wound healing researchers worldwide.” Nutrition The Latest in… By Dulcie Ward, R.D., and Susan Levin, M.S., R.D. FERTILITY Low-Fat Dairy Products Linked to Increased Infertility Risk © istockphoto A new study found low-fat dairy product consumption is linked to an increased risk of infertility. A total of 18,555 premenopausal women from the Nurses’ Health Study II who attempted a pregnancy or became pregnant between 1991 and 1999 were evaluated for the association between dairy products and infertility. Women who consumed two or more servings per day of low-fat dairy products had 1.85 times the risk for infertility. While total dairy product intake was not associated with an increased risk of infertility, the majority of fat in dairy products is saturated fat, which is linked to increased cholesterol, insulin resistance, overweight and obesity, and other health problems. Chavarro JE, Rich-Edwards JW, Rosner B, Willet WC. A prospective study of dairy foods intake and anovulatory infertility. Hum Reprod. 2007;22(5):1340-1347. Meat-Eating Moms Have Less-Fertile Sons countries to compensate for the bone loss resulting from diets high in animal protein, sodium, and other calcium wasters. The World Health Organization acknowledges that less dietary calcium is needed when animal protein consumption is low. habits of their mothers from the Study for Future Families. The more beef a mother consumed, the lower her son’s sperm concentration. Sperm count was 24 percent higher in men whose mothers consumed less beef. The difference may be due to steroid hormones found in animal products. Six hormones are commonly used in the United States to induce increased growth and development in cows, and measurable levels are routinely present in the animals’ muscle, fat, liver, kidneys, and other organs. Cattle raised without extra hormones still have significant hormone levels in their tissues because of endogenous hormone production, and the nutrient profile of animal products tends to elevate hormone levels in the human body. Payne ME, Anderson JJB, Steffens DC. Calcium and vitamin D intakes are positively associated with brain lesions in depressed and nondepressed elders. Presentation at the meeting of American Society for Nutrition: Experimental Biology 2007. May 1, 2007, Washington, DC. Swan SH, Liu F, Overstreet JW, Brazil C, Skakkebaek NE. Semen quality of fertile US males in relation to their mothers’ beef consumption during pregnancy. Hum Reprod. Advance access published on March 28, 2007. A new study in Human Reproduction finds that a pregnant woman’s meat consumption can reduce her future son’s sperm count. Researchers at the University of Rochester in New York analyzed the relationship between various sperm parameters of 387 men and the eating BRAIN HEALTH © istockphoto High Calcium and Vitamin D Intake May Lead to Cognitive Impairment © istockphoto D uke University researchers recently found an association between a high dietary intake of calcium and vitamin D and brain lesion volume in elderly men and women. Researchers believe that the problem may be due to the effects of calcification and bonelike formations in blood vessels. Vitamin D enhances calcium absorption and may accelerate this process. Investigator Martha Payne designed this study after finding a similar association between high-fat dairy products and brain lesions. Current dietary calcium and Vitamin D recommendations for adults over 50 years of age are 1,200 mg and 400 to 600 I.U., respectively. The findings suggest that these recommendations may be too high for portions of the general population. Calcium recommendations are set high in Western PARKINSON’S DISEASE Dairy Products Linked to Parkinson’s Disease A new study from the American Journal of Epidemiology links the consumption of dairy products to an increased risk for Parkinson’s disease. Researchers studied this association among 388 men and women with Parkinson’s disease participating in the American Cancer Society’s Cancer Prevention Study II. Those who consumed the most dairy milk had a 70 percent greater risk for the disease. Chen H, O’Reilly E, McCullough ML, Rodriguez C, et al. Consumption of dairy products and risk of Parkinson’s disease. Am J Epidemiol. 2007;165:998-1006. Summer 2007 GOOD GOOD MEDICINE MEDICINE Winter 2006 Art of Compassion Weekend PCRM Celebrates O n April 14, Washington, D.C.’s historic Mellon Auditorium was transformed into a glamorous setting for hundreds of PCRM supporters who traveled from across the country and as far away as Europe to celebrate the organization’s successes and look forward to the future. The event included plenty of star power, with Alec Baldwin serving as the evening’s master of ceremonies. He was joined by Marilu Henner, House’s Lisa Edelstein, Persia White of TV’s Girlfriends, musician Moby, and daytime drama stars Peggy McCay and Grant Aleksander. International music star Shani Rigsbee performed during the program. Sublime in Ft. Lauderdale, Fla., provided a caramelized onion tart as the first course; San Francisco’s Millennium served an entrée of seared polenta nera presented over a bed of spring vegetable ragout, fennel Congresswoman Stephanie Tubbs Jones (Ohio) Master of ceremonies Alec Baldwin Singer Shani Rigsbee 2005 Art of Compassion Award winner Nanci Alexander GOOD MEDICINE Summer Summer 2007 2007 Henry Heimlich, M.D., and actress Lisa Edelstein Mike Wilkinson Front row: Neal D. Barnard, M.D., and Alec Baldwin. Back row: actress Persia White, musician Moby, Shani Rigsbee, actress Marilu Henner, Michael Brown, Lisa Edelstein PCRM president Neal D. Barnard, M.D. Art of Compassion Weekend seitan sausage, and porcini mushrooms; New York’s Candle 79 treated guests to hors d’oeuvres; and famed macrobiotic chef Eric Lachasseur created an incredible dessert buffet. Participants bid on silent auction items such as vacation getaways, celebrity-autographed scrubs, and gift packages to raise critical funding for PCRM’s programs. Artist Peter Max donated a rare chance to have him paint a personalized portrait, and Alec Baldwin Gala-Goers Treated to a Full Day of Good Health Professional Athletes Lead Fun Run, Provide Nutrition Tips Mike Wilkinson P and Moby donated a private dinner and concert. The incredible enthusiasm and generous support of PCRM members made the gala an extraordinary event. You can view more gala images at www.pcrm. org/gala2007. Actor Grant Aleksander and actress Peggy McCay Marilu Henner and Chef Sualua Show How It’s Done M arilu Henner, who became America’s darling on the hit shows Taxi and Evening Shade, was joined by leading chef Sualua Tupolo to show gala attendees how to create dishes that are both healthful and full of flavor. The first class took attendees on a culinary tour of Washington, including mock crab cakes (in honor of Maryland, our neighbor to the north), Senate Bean Soup, and White House Butternut Squash Salsa. Although Marilu continues a vigorous acting career, her passion is fitness and nutrition through her Total Health Makeover® and her Web site, Marilu.com. rofessional Ironman triathlete Brendan Brazier, who won the Canadian 50K Ultramarathon in 2003 and 2006, when he also set the course record, led an early-morning four-mile run around the National Mall. The approximately 20 participants got an up-close view of the Washington Monument, the World War II Memorial, the Capitol, and the Lincoln Memorial. Afterward, Brazier, who created a health food supplement and has written two books, was joined by professional bodybuilder Kenneth Williams to give the runners nutrition PCRM and The George and training tips. Brazier explained how Washington University a vegan diet helped him trim his recovery times and dramatically improve his Present Nutrition in athletic performance and Williams, who Clinical Practice is America’s first vegan bodybuilding edical professionals had a full day of champion, served as living proof that a detailed instruction on using nutriplant-based diet provides super strength tion in clinical practice. PCRM partnered and exceptional health. with The George Washington University to present the continuing medical education program for health care professionals. The course provided an overview of how to put nutritional interventions to work and focused on the most recent evidence that links nutrition to the management of common medical conditions. The seminar covered a variety of topics, including cardiovascular health, diabetes management, cholesterol control, women’s health, cancer prevention and survival, and other topics. The speakers were Neal D. Barnard, M.D.; Caldwell B. Esselstyn Jr., M.D.; Hope Ferdowsian, M.D., M.P.H.; David J.A. Jenkins, M.D., Ph.D., Sc.D.; Gordon Saxe, M.D., Ph.D., M.P.H.; and Caroline Trapp, M.S.N., A.P.R.N., B.C.ADM, C.D.E. More than 200 primary care physicians, physician assistants, nurse practitioners, dietitians, subspecialists, and others interested in nutrition and chronic disease management attended the event. PCRM hopes that this is just the first of many continuing education programs jointly sponsored with The George Washington University. M Summer 2007 2007 GOOD GOOD MEDICINE MEDICINE Summer Art of Compassion Weekend PCRM Recognizes Compassion and Innovation in Awards Ceremony T GOOD MEDICINE Summer Summer 2007 2007 Congressman Jim Moran (Virginia) Photographer Medicine winner To help researchers make the transition Dr. Daran Haber, Art of Compassion to human-based tis- Award winner sues, Charlton founded Asterand. With exacting quality-control methods for tissue collection at participating hospitals, the company now supplies human tissues for research on Alzheimer’s disease, breast cancer, and many other conditions. Asterand was named Michigan’s hightechnology company of the year in 2005. Daran Haber, M.D., received from Nanci Alexander and Alec Baldwin the Art of Compassion Award, which recognizes an individual who exemplifies compassion to an extraordinary degree and works to extend this value as broadly as possible. Dr. Haber, a board-certified anesthesiologist and pain management specialist at Riverview Medical Center in Red Bank, N.J., testified before the New Jersey State Assembly Education Committee on behalf of a successful bill guaranteeing a student’s right not to dissect animals and spoke out on behalf of 300 neurologists and neurosurgeons against a class at Ohio State University that inflicts severe damage to the spinal cords of mice and rats. Dr. Haber, a longtime PCRM member, has also appeared in several of PCRM’s television public service announcements, helping to spread the word about diet, health, and cancer prevention. PCRM also presented certificates to two members of Congress for their contributions to health and compassion. Congresswoman Stephanie Tubbs Jones of Ohio was recognized for her ongoing promotion of good nutrition, and Congressman Jim Moran of Virginia was honored for his commitment to the welfare of animals in laboratories. Mike Wilkinson he Art of Compassion gala honored three individuals for their outstanding contributions to science and PCRM’s mission. The Benjamin Spock Award for Compassion in Medicine was presented by Dr. Spock’s widow, Mary Morgan, and musical superstar Moby to David J.A. Jenkins, M.D., Ph.D., D.Sc., of the University of Toronto and St. Michael’s Hospital. Dr. Jenkins has provided the scientific basis for an all-out assault on unhealthy eating patterns that take root in childhood. First, he developed the glycemic index, which revolutionized the nutrition world by quickly and easily demonstrating how various foods affect the body, and then he developed the Dr. David J.A. Jenkins, Benjamin Spock Award for Compassion in most rapid and Medicine winner, and Mary Morgan powerful dietary method to lower cholesterol: a vegetarian diet incorporating a portfolio of cholesterol-lowering foods. Dr. Jenkins is a visionary who insists on an awareness of the broad effects of our diet choices, for ourselves and for generations to come. Randal Charlton, founder and CEO of Asterand, received the Henry J. Heimlich Award for Innovative Medicine from Dr. Heimlich himself along with House actress Lisa Edelstein. Like Dr. Heimlich, Charlton is the embodiment of innovation and compassion. Charlton recognized that pharmaceutical manufacturers needed to go beyond research with animals and animal tissues, which often led to results that Randal Charlton, Henry J. Heimlich Award for Innovative failed to apply to humans. Research Issues Duke University Eliminates Animal Labs in Medical Teaching Duke University T he number of medical schools using live animals for student training is dwindling quickly. After years of encouragement from PCRM, Duke University has finally joined the nearly 90 percent of U.S. medical schools that have completely eliminated live animals from their undergraduate medical education curricula. The school’s live pig lab was replaced with modern nonanimal teaching methods. This shift at Duke brings the number of U.S. medical schools that still use live animal labs to only 13. Twenty years ago, live dogs and pigs were commonly used in physiology, pharmacology, and surgery courses. A standard laboratory exercise involved anesthetizing the animal, followed by injecting pharmaceuticals or practicing surgical techniques. The animals were typically killed after the laboratory. In many top-ranked medical schools, surgery instruction is now focused on the use of simulators such as Simulab’s TraumaMan™ and laparoscopic surgery trainers, as well as didactic teaching, class and small-group case discussions, interactive computer-based methods such as virtual reality programs, and hands-on mentorship opportunities with faculty in anesthesiology, surgery, emergency medicine, and other clinical disciplines. Pushing the March of Dimes Toward Compassionate Research PCRM P articipants at March of Dimes WalkAmerica events seek to support the organization’s research and services. Most have no idea that the charity funds animal experiments, some of which have been extraordinarily cruel. So PCRM helped educate them with mobile billboards and volunteers at WalkAmerica events across the country. Mobile billboards were placed at WalkAmerica events in Washington, D.C., Ft. Lauderdale, Fla., Dallas, Houston, Tucson, Ariz., and Atlanta. Walkers in Peoria, Ariz., received PCRM’s message from an aerial banner circling overhead. Many PCRM members and volunteers across the country helped pass out more than 40,000 leaflets in April alone and answer questions at their local WalkAmerica events. Over the years, the March of Dimes has funded a series of controversial experiments, including sewing shut the eyelids of newborn kittens; injecting pregnant animals with cocaine, nicotine, and alcohol; tethering pregnant monkeys to cages with monitoring cables running through the mothers’ uteruses and into their fetuses’ bodies; and deliberately injuring the lungs of newborn lambs. Not only are these experiments cruel but they have also failed to lead to advances in preventing or understanding birth defects. The rates of almost all birth defects have either remained steady or increased in this country. The number of preterm births has risen steadily since 1969, and the rate of maternal mortality has not improved since the 1980s. While the March of Dimes does not reveal the exact amount spent on animal experiments, estimates go up to $30 million. PCRM is encouraging the organization to devote this money to worthwhile services, including prenatal care, education, social programs, and humanbased research. To find out how you can help reform the March of Dimes, visit www.ReformtheMarchofDimes.org. Summer 2007 GOOD MEDICINE Research Issues New Approved Tests to Spare More Than 250,000 Animals in European Union T he European Union has announced that non-animal methods will likely soon replace rabbits for testing chemicals that could be irritating to the skin or eye. Another new method will halve the number of mice used in skin allergen testing. These advances will save almost 20,000 rabbits every year and a total of about 240,000 mice. Under EU law, animal tests for drugs, chemicals, and personal products cannot be used if an alternative non-animal method has been validated by the Scientific Advisory Committee of the European Centre for the Validation of Alternative Methods (ECVAM) and implemented by the European Commission. This April, ECVAM approved five tests that obviate the use of rabbits and mice for certain assessments. Two of the new tests use laboratory-grown human skin to predict whether chemicals could irritate the skin. These methods are much more reliable than the Draize skin irritation test, in which chemicals are tested on the skin of rabbits. Two other tests use animal tissues obtained from slaughterhouses rather than live rabbits to assess the severity of eye irritants. Finally, half of the mice to be used in skin allergen testing under new EU chemicals legislation will be saved by a new reduction procedure. The EU is far ahead of ECVAM’s U.S. counterpart, the Interagency Coordinating Committee for the Validation of Alternative Methods (ICCVAM), a government agency charged with assessing alternative methods for U.S. agencies. ECVAM has approved more than 23 methods, while ICCVAM has approved only six. Send a Free Dissection E-Card T ACTION ALERT Help End Animal Dissection in Local Schools D o you—or does your child—attend a school that still uses animals for dissection? If so, you can encourage teachers and school administrators to implement humane alternatives. Research shows that cruelty-free alternatives teach concepts of anatomy and biology as well as or better than traditional dissection—all without sacrificing compassion for animals. Contact your superintendent and express your concern about animal dissection. Ask him or her to begin using humane and costefficient non-animal teaching tools in the new school year. You’ll find a sample letter and more information at www.DissectionAlternatives.org. 10 GOOD MEDICINE Summer Summer 2007 2007 hink classroom dissection should become a thing of the past? Encourage the students, teachers, and parents in your life to learn about dissection alternatives by sending them a free e-card. Besides the concerns about animal welfare, environmental damage, and chemical exposures, there is simply no educational advantage to dissection. Study after study has shown that students who learned with interactive CD-ROMs, videos, and even simple lectures performed as well or better than their peers who performed dissection. And as educational technology advances, new alternatives are becoming extremely detailed and lifelike, and they allow students to perform “dissections” as many times as they need to master the concepts. Four different e-cards are available, each featuring a commonly dissected creature. To send an e-card or get a free copy of Digital Frog 2, visit www. DissectionAlternatives.org. Nutrition & Prevention Success Stories iSTOCKPHOTO Tackling Diabetes with Simple Diet Changes T he calls and e-mails have been pouring in to PCRM since Dr. Neal Barnard’s Program for Reversing Diabetes hit bookstores in January. Individuals with diabetes from all over the United States are contacting us to share their success with Dr. Barnard’s program. We’ve heard from people who began the program the week they were diagnosed with diabetes and people who sought a change after battling the disease for 10 years or more. Some people were already eating fairly healthfully, and some people had never before heard the word “vegan.” But one person after another has shared a story of weight loss, improved health, reduction of medications, and a renewed faith in the power of nutrition. Following are the stories of four very different people who all experienced powerful improvements in their health with simple diet and lifestyle changes. IRA GOLDBERG I ra Goldberg never imagined the difference a healthy diet could make. In fact, when the 41-year-old high school history teacher first heard the word “vegan” mentioned in the diabetes class he had enrolled in, he turned to his wife and said, “I don’t think so.” That was one year and 65 pounds ago, and today Goldberg proclaims that having become a vegan is one of the things he is proudest of in his life. Goldberg enrolled in Caroline Trapp’s Food for Life to Prevent and Reverse Diabetes, a PCRM-sponsored pilot program in the Detroit area, five years after he was diagnosed with diabetes. His A1c (a commonly used index of blood glucose control) was through the roof at 10.8. Trapp told him about a lifestyle he could take on Ira Goldberg Age: 41 Location: West Bloomfield, Mich. A1c: June 2006: 10.8 Feb. 2007: 5.3 Total Cholesterol: June 2006: 249 Feb. 2007: 179 Medications: Has stopped cholesterol medication. Taking one-fourth the amount of diabetes medication (metformin); hopes to be off medication completely. Pounds lost: 65 Summer Summer 2007 2007 GOOD GOOD MEDICINE MEDICINE 11 Nutrition & Prevention that didn’t involve counting calories or limiting portion sizes. With his wife’s support, Goldberg decided to jump in. After the first few weeks, Goldberg realized that the diet was something he could do. As someone who eats out several times a week, realizing that he could easily find something to eat at restaurants was a turning point. “I never came close to not finding something to eat at restaurants,” Goldberg said. Goldberg counts cooking at home, finding the perfect tofu, and making sure that everything he eats is truly low-fat as among the most challenging parts of the diet. “But I have the vegan part down, no problem,” Goldberg said. In fact, he says that eating animal products now seems foreign to him. “This journey started off as a way of fulfilling a health need, but has really evolved into a personal awakening that has left me a more well-rounded person, and I really feel good about what I’m doing for other living beings,” Goldberg said. ANNE HERNDON Anne Herndon Age: 61 Location: Winston-Salem, N.C. A1c: Nov. 2006: 6.3 June 2007: 5.7 Medications: Never began diabetes medications Pounds lost: 35 (in one year); now at healthy weight Latest update: Anne is now putting together a packet of recipes and pantry staples for her doctor to hand out to her other patients. W hen Anne Herndon was diagnosed with diabetes in June 2006, her doctor gave her three months to lower her A1c. The 61-year-old retired psychologist started making changes right away: She followed the dietary guidelines of the American Diabetes Association (ADA) and cut out “white” processed foods, cut out wine, and began exercising every day. By October, her weight had dropped but her other numbers hadn’t budged. Impressed by Herndon’s weight loss, her doc12 12 GOOD MEDICINE MEDICINE Summer GOOD Summer 2007 2007 tor gave her three more months to get her numbers down before turning to medication. Herndon wasn’t really sure what else to do besides continuing to follow the ADA dietary guidelines and keep exercising. In November—two months before Dr. Barnard’s book appeared—her friend pointed her to Dr. Barnard’s research about a low-fat vegan diet. Figuring she had nothing to lose, she began the new diet right away. Herndon was already eating plenty of fresh and seasonal fruits and vegetables and only had meat (usually fish) a few times a week, so the transition for her was quite simple. She cut out the meat, began putting soymilk on her breakfast oatmeal instead of skim milk, and continued to eat an abundance of produce from her local farmers’ market. When Herndon went back for testing in January, not only had her weight dropped but this time her A1c had fallen to 5.8. Both Herndon and her doctor were impressed. Herndon has been enjoying every aspect of the diet and is “thrilled with what’s in the refrigerator.” She’s so enthusiastic that she has offered herself as a guide for anyone wanting to make the transition to a low-fat vegan diet. “I would love for someone to say to me ‘I want to change to a vegan diet, will you help me?’” Herndon said. JOHN BEALE J ohn Beale was already taking medication for high blood pressure and high cholesterol. So when he was diagnosed with diabetes this past January, Beale was not thrilled with the thought of taking more pills. A dietitian who looked at his already fairly healthy diet and active lifestyle felt that medication was essential. Beale was frustrated, and he knew there must be something else he could do. He went home, got on the Internet, and began educating himself about diabetes. Within 48 hours, Beale had read Dr. Neal Barnard’s Program for Reversing Diabetes cover to cover. He took Dr. Barnard’s advice and began the program without compromise: The first day he and his wife replaced all the “no” foods in the kitchen with “yes” foods. After one week on the program, his blood sugar and weight began coming down. After eight weeks, his blood pressure was below normal, he’d lost 32 pounds, and his doctor cut his cholesterol medication by half. In the class he participated in at the Nutrition & Prevention was very surprised and incredibly relieved,” Peters said of her Age: 59 immediate improvements. “I just Location: Madison, Wis. didn’t think that for someone A1c: Jan. 2007: 7.0 who hadn’t eaten meat in a very April 2007: 6.0 long time that just cutting out the Fasting glucose cheese and the eggs could have Jan. 2007: in the 250s such an effect.” Peters’ physi April 2007: in the 80s cian was so impressed by Peters’ Cholesterol: Jan. 2007: 143 improvement that she’s “going April 2007: 42 to read Dr. Barnard’s book from Medications: Went off blood pressure cover to cover,” Peters said. medication, cholesterol medication Peters has cut out dairy has been cut in half, never on diabetes products, cut back on refined medications carbohydrates, and is eating Pounds lost: 32 many more fruits and vegetables. clinic for all newly diagnosed diabetics, two-thirds of She’s also discovering foods like quinoa and ethnic his classmates ended up buying the book after talking foods that she probably would not have found before. An added bonus: Her 53-pound weight loss has given with Beale about his progress. Beale’s biggest challenge was learning to read labels her renewed energy and a new wardrobe. “I never ever and shop for food, “but in hindsight it was a wonderful thought I’d feel this good again,” Peters said. education,” he said. Beale begins his day with oatmeal “As discouraging and as frustrating as it can be and fruit, has a salad for lunch, and has anything from to be newly diagnosed with type 2 diabetes, people pasta to homemade soups to cheeseless pizza for dinner. should realize there is a very simple way back to a He and his wife are even making their own homemade healthy life,” Peters said. “For the payoff you get, it’s not that hard.” veggie burgers. Beale has found people to be very inquisitive about Dr. Barnard’s program, which Beale believes is the only ard’s hopeful message for diabetics out there. k Dr. Neal Barn iSTOCKPHOTO John Beale JANE PETERS y of the boo 1. To order a cop tes, see page 2 e b ia D g in rs e ev Program for R J ane Peters has been a vegetarian for 15 years. So when she was diagnosed with type 2 diabetes in September 2006 and her doctor said that vegetarians can’t control their diabetes, she became frustrated. When a nurse at the diabetes education center gave her the same news, she felt dejected. That afternoon, the Autumn 2006 issue of Good Medicine arrived in her mailbox with a “Targeting Diabetes” cover story detailing Dr. Barnard’s findings that a low-fat vegan diet works to control diabetes better than the traditional diabetes diet. “I felt like someone had thrown me a lifeline,” Peters said. “I started the diet that day.” After Jane switched her diet, she also switched her doctor. She found a doctor who was very supportive of her new lifestyle. And after just four months on the diet, Peters’ numbers were so low her doctor took her off the metformin that she was initially prescribed. “I Jane Peters Age: 54 Location: Newtown, Penn. A1c: Sept. 2006: 8.9 April 2007: 4.7 Fasting glucose: Sept. 2006: 385 April 2007: between 80 and 95 Cholesterol: Sept. 2006: 190 April 2007: 140 Medications: Stopped diabetes medications. Pounds lost: 53 Summer 2007 GOOD MEDICINE 13 Nutrition & Prevention Meet Caroline Trapp, M.S.N., A.P.R.N., B.C.-ADM, C.D.E. C aroline Trapp recently joined PCRM as the director of diabetes education and care. Board-certified in adult primary care, advanced diabetes management, and diabetes education, she has worked with people with diabetes for more than 20 years. Her role at PCRM is to oversee new diabetes prevention and reversal initiatives. For professionals, she is cre- P anchero’s Mexican Grill has added a lot of flavor to PCRM’s Food for Life to Prevent & Reverse Diabetes pilot classes, led by Caroline Trapp, in the Detroit area. The chain has provided participants in the class the opportunity to learn to choose the kinds of low-fat vegan foods that will help them manage their diabetes in a real-world setting. Eliminating all animal products from one’s diet can be intimidating to some peole at first. However, the field trip to Panchero’s Mexican Grill allows participants to see that they can enjoy generous portions of delicious foods while managing their diabetes. The Livonia, Mich., Panchero’s location treated class participants to a choice of four vegan entrées from the regular menu. Trapp’s students have particularly enjoyed the vegetarian burrito, which is a good-sized tortilla handmade in front of customers, filled with black or pinto beans, cilantro, rice, roasted vegetables, corn, and salsa. “The food at Panchero’s is delicious and fresh,” said Dolores Stachura, a student of Trapp’s. “I’ll be back!” 14 14 GOOD MEDICINE MEDICINE Summer GOOD Summer 2007 2007 Don’t Forget Your Vitamin B12 A vegan diet rich in fruits, vegetables, whole grains, and legumes provides plenty of protein and an abundance of vitamins and minerals to meet nutritional needs. You’ll find plenty of calcium in green leafy vegetables and legumes. However, there is one nutrient that merits a bit of simple planning. Vitamin B12, which is essential for healthy nerves and healthy blood, is STIRLING ELMENDORF Panchero’s Serves Up a Lesson in Nutrition ating new continuing medical education programs and patient education materials. For individuals with diabetes, she is continually updating materials on www.pcrm.org/ diabetes, including acting as a forum moderator for the GetHealthy Club, PCRM’s online support group. Trapp championed the creation and implementation of the pilot PCRM Food for Life to Prevent & Reverse Diabetes classes in the Detroit area, the first site outside of Washington, D.C., to host these classes. This diabetes course was designed by physicians, certified diabetes educators, and other nutrition experts and is based on Dr. Neal Barnard’s research showing that a low-fat vegan diet can help individuals with diabetes cut their blood sugars, reduce their medications, lose weight, and trim their cholesterol levels. The classes have already helped many individuals gain control over their diabetes by teaching proper nutrition, behavioral skills, and diabetes self-care methods. As a nurse practitioner specializing in diabetes, Trapp was successful in helping her practice achieve Diabetes Provider Recognition from the American Diabetes Association/NCQA and also the (Michigan) Governor’s Award for Excellence in Diabetes Care. Trapp is a volunteer lecturer at the University of Michigan’s School of Nursing. not produced by animals or plants. It is formed by bacteria and other one-celled organisms. Animal products commonly contain B12 formed by bacteria in animals’ intestinal tracts. While B12 is also formed in the human intestine, it occurs after the point where the vitamin can be readily absorbed. Vitamin B12 needs can be met by consuming a variety of supplemented foods, including fortified breakfast cereals, fortified soymilk, fortified meat analogues, and some brands of nutritional yeast. However, the Nutrition & Prevention PCRM’s Complaint Halts Misleading Dairy Advertisements T wo national dairy advertising campaigns overseen by the U.S. Department of Agriculture will stop claiming that dairy products cause weight loss, the Federal Trade Commission (FTC) announced in early May. The decision, which comes in response to a petition filed by PCRM, will end misleading claims made in the “Milk Your Diet. Lose Weight” and “3-A-Day. Burn More Fat, Lose Weight” promotions. In the FTC petition, PCRM charged that the dairy industry has used false and misleading advertising in its multimillion-dollar marketing campaign suggesting that consuming milk and other dairy products causes weight loss. In response, the FTC’s Division of Advertising Practices met with USDA staff and representatives of the National Fluid Milk Processor Promotion Board and the National Dairy Promotion and Research Board, who agreed to discontinue all advertising and most convenient and reliable source is a daily multivitamin. All common brands for children and adults contain more than enough B12. Spirulina, miso, and seaweed are not reliable sources of vitamin B12. We recommend that all adults and children take a daily multivitamin or a B12 supplement of at least 5 micrograms per day. The recommended dietary allowance for adults is 2.4 micrograms per day, with increased requirements for women who are pregnant or breastfeeding. Most cases of B12 deficiency have other marketing activities involving weight-loss claims. Available research does not support the claim. “It is important to recognize that the dairy industry, which used to have a mom-and-pop image, is a huge commercial entity that will exaggerate to sell its products,” said PCRM president Neal Barnard, M.D. The news of this consumer victory was covered by many major media outlets, including The New York Times, CNN, and The Today Show. The dairy industry’s weight-loss campaign was based largely on three small studies conducted by Michael Zemel, Ph.D., a professor of nutrition at the University of Tennessee whose funding came from dairy industry sources and who patented the dairy-weight-loss claim. Out of 27 randomized, controlled research trials investigating the effects of dairy nothing to do with diet. Rather, individuals who lose their ability to absorb the vitamin become deficient no matter what sort of diet they follow and need treatment with injectable or high-dose oral B12. In the nonindustrialized world, where bacterial contamination commonly brought traces of B12 to foods, B12 deficiency is largely prevented. However, modern hygiene has eliminated this source, just as indoor living has largely eliminated sunlight, nature’s source of vitamin D. A daily multivitamin restores these essential nutrients. The dairy industry has banked on consumers not taking an overly close look at its health claims. products on body weight, Dr. Zemel’s were the only ones showing a link between dairy consumption and weight loss. The dairy industry has banked on consumers not taking an overly close look at its health claims. A review by PCRM nutritionist Amy Lanou, Ph.D., published in the March 2005 issue of Pediatrics, showed that there is little scientific evidence to support the idea that drinking milk helps children build strong bones. Researchers who hoped that milk would help prevent hip fractures later in life found no such evidence after an 18-year investigation as part of the Nurses’ Health Study. Also, yet another study has linked milk to prostate cancer: A new study in the International Journal of Cancer found that as consumption of dairy products or overall dietary calcium intake increased, risk for prostate cancer increased. In a survey of 29,133 men, those who consumed the most dietary calcium (greater than 2,000 milligrams per day) had a 63 percent greater risk, compared with those consuming less than 1,000 milligrams per day. Summer 2007 GOOD MEDICINE 15 The Cancer Project The Cancer Project Update More Praise for the Cancer Project T he Cancer Project’s instructors are changing lives across the country. Here’s a letter of praise from Dr. Chris Gordon: April 27, 2007 I am writing to express my admiration and gratitude for a session of The Cancer Project that was presented here at Advocates on April 26, 2007, by chef Rose Lee. Our agency supports people with a variety of disabilities, including psychiatric, developmental, other cognitive disabilities, and physical disabilities. For many of the people we support—especially people with psychiatric disabilities—poor nutrition contributes very substantially to significant morbidity and early mortality. On average, people with psychiatric disabilities die 15 years younger than their non-disabled peers, primarily due to cardiovascular and pulmonary disease. Rose Lee was magnificent!!! She met with a group of over 40 people with disabilities and staff members. Many consumers had hearing impairments, many needed staff assistance of various kinds, and we were a big group. Nonetheless, Rose engaged us all with lively and informative material and a warm, engaging style. She prepared a wonderful, delicious meal, using techniques and ingredients that were easily accessible to all of the audience. Everyone had a wonderful time, learned a lot and raved about both the food and the experience. Everyone is hoping that Rose will be able to return. This was truly a wonderful learning experience for all of us—including me, the Medical Director! I am definitely going to modify my diet on the basis of this terrific presentation. Keep up the fantastic work! Sincerely, Chris Gordon, M.D. Vice President, Clinical Services Medical Director Advocates, Inc. Framingham, MA More Cancer Project News • Attention health professionals! The Cancer Project will be hosting its second annual Cancer & Nutrition Symposium on Saturday, July 28, in Bethesda, Md. The symposium will provide breakthrough information on how foods fight cancer and will feature top researchers and authors T. Colin Campbell, Ph.D.; Lawrence H. Kushi, Sc.D.; John McDougall, M.D.; June Chan, Sc.D., and The Cancer Project’s president, 16 GOOD MEDICINE Summer 2007 Neal Barnard, M.D. To sign up, visit www.CancerProject. org/Symposium. • Are your children developing healthy eating habits? The earlier children start eating a nutritious diet rich in cancerfighting foods, the greater their chances of staying healthy for life. The Cancer Project is now offering Nutrition for Your Kids: A Dietary Approach to Cancer Prevention. The booklet provides information on how diet affects cancer risk and includes nutrition information for children in every age group, delicious recipes, and tips on how to instill healthful eating and exercise habits in kids. To order your free booklet, visit www.CancerProject.org/kids. The News You Need The Cancer Project By Chelsea Lenge, R.D., and Neal D. Barnard, M.D. the stomach. N-nitroso compounds are formed in the body by a chemical process that starts with nitrates such as cured meats and dairy products. Antioxidants, such as vitamin C, usually neutralize these potential carcinogenic compounds by turning them into nitric oxide. Researchers from the study found that consuming fat may cause N-nitroso compounds to re-form in the stomach. Fat counters vitamin C benefits. BBC News. April 8, 2007. ©iStockphoto Flavonoids May Decrease Pancreatic Cancer Risk R Carcinogens in Cooked Meat Increase Breast Cancer Risk R esearchers at the University of South Carolina recently evaluated the effects of exposure to two carcinogenic compounds found in cooked meat—polycyclic aromatic hydrocarbons (PAHs) and heterocyclic amines (HCAs)—and breast cancer risk. The study found that postmenopausal women who consumed grilled, barbecued, or smoked red meat more than once a week had a 47 percent increased risk of developing breast cancer over their lifetime, compared with women who ate meat less than one time per week. Breast cancer risk increased to 74 percent for women who consumed meat and ate fewer than five servings a day of fruits and vegetables. PAHs and HCAs are formed when barbequing, grilling, smoking, and pan-frying meats at high temperatures. Exposure to these harmful substances can be limited simply by eating a plant-based diet that is rich in beans, fruits, vegetables, and whole grains. esearchers from the Cancer Research Center of Hawaii found that consuming foods rich in flavonoids may decrease pancreatic cancer risk by as much as 23 percent in nonsmokers and 59 percent in smokers (smokers generally have a higher pancreatic cancer risk). Foods rich in flavonoids include apples, broccoli, onions, kale, and berries. These compounds play important roles in cancer prevention and survival, including apoptosis or cancer cell death. The study was part of the ongoing, eight-year Multiethnic Cohort Study involving 183,518 participants. Investigators looked at three specific classes of flavonoids—quercetin, kaempferol, and myricetin. Kaempferol was found to have the strongest cancerfighting effects in smokers. Foods rich in kaempferol include grapefruit, spinach, and cabbage. Nöthlings U, Murphy SP, Wilkens L, Henderson BE, Kolonel LN. Flavonols and pancreatic cancer risk: the multiethnic cohort study. Presented at the Annual Meeting of the American Association for Cancer Research. April 2007. Abstract 856. ©iStockPHOTO Steck SE, Gaudet MM, Eng SM, et al. Cooked meat and risk of breast cancer—lifetime versus recent dietary intake. Epidemiology. May 2007;18:373-382. Fat May Inhibit the Beneficial Effects of Vitamin C R esearchers from the University of Glasgow found that fat in foods diminishes the ability of vitamin C to protect against cancer-forming compounds in www.CancerProject.org The Cancer Project is a nonprofit PCRM subsidiary that advances cancer prevention and survival through nutrition education and research. Summer 2007 GOOD MEDICINE 17 Member Support The Art of Compassion Gala Bringing Out the Best in All of Us T he Art of Compassion gala was an enormous success by all accounts. The historic venue in the heart of Washington, D.C., was a magnificent setting, funds were raised to support PCRM’s programs, and guests enjoyed each other’s company, wonderful food, and a star-studded celebration. But by far the biggest impact that the event had on the organization is how it brought people together in support of PCRM’s work. The outpouring of support for the Art of Compassion gala was felt from the moment we announced this huge undertaking. Restaurants, performers, auction donors—and more sponsors than we’ve Betsy Wason Director of Development Including PCRM in Your Will Please send me information about: A bequest is an important way to ensure that your resources work for the causes you support. The following sample is language that may be used in a will: bequests “I give, devise, and bequeath to the Physicians Committee for Responsible Medicine, Inc., federal tax identification number 52-1394893, 5100 Wisconsin Ave. NW, Suite 400, Washington, DC 20016, the sum of $_______ (or describe the real or personal property or percentage of the estate) as a charitable contribution to be used for its general purposes.” Explore more gift options to help you achieve your goals at pcrm.planyourlegacy.org. 18 GOOD MEDICINE Summer Summer 2007 2007 gift annuities other planned gifts Name Address City State/Province zip/Postal Code Country E-mail Phone Please mail to: The PCRM Foundation, Attn: Membership Dept. 5100 Wisconsin Ave. NW, Suite 400 Washington, DC 20016. Or visit our planned-giving Web site at http://pcrm.planyourlegacy.org. GM07SM Mike Wilkinson PCRM supporters Cammie and Meg Wolff with Neal Barnard, M.D., president of PCRM ever had before—backed up our gala plan with action and funding that allowed us to pull off the event in such a grand way. And when it came time for staffing, our volunteers generously came forward to ensure that the evening ran smoothly and to account for every detail. Celebrating together is important. However, the “best” in all of us goes way beyond tuxedos and gorgeous gowns. During the evening, we heard over and over how important it was that PCRM keep working toward a day when medicine will not involve needless suffering. We heard how you value your health and how you value compassion. Your “best” carries way beyond any special occasion. So while we have the momentum of the gala driving us forward, let me encourage you to continue giving PCRM your best, because it’s the incredible support of our membership that will ultimately result in a compassionate future. Keep up the great work! Member Support Kim Howe A Strong Voice for PCRM A s a dedicated supporter of PCRM and its mission, Kim Howe is a PCRM Lifetime Partner and the 2006 sponsor of PCRM’s campaign to promote alternatives to dissection in schools. She has also begun to lend her own voice to PCRM’s message of compassion and ethics in research and a healthy vegetarian diet to promote health and prevent disease. Kim recently joined Toastmasters to be able to hone her own speaking skills and become a stronger voice for what she believes in. To drive home her message, she includes PCRM materials in her presentations and makes them available to her audiences. Kim recently traveled to Washington, D.C., for PCRM’s Art of Compassion Gala where she again pledged to sponsor one of PCRM’s programs. This year, she is sponsoring the campaign to end live animal labs in medical research and education. Kim lives in Calabasas, Calif., with her dog, Daisy, whom she and her late husband, Robert, found abandoned on the streets of Phoenix. Daisy is one of a long line of rescued dogs that have shared the Howe home. “I have been interested in animal issues since I was a child,” Kim said. “My mother taught me how important it was to be kind to them. Most people think of animals as things to be used and thrown away. They do not stop to think that they have feelings and that we do not have the right to inflict pain on them and abuse them.” Asked why she chooses to support PCRM, Kim emphasized that it is because PCRM presents a scientific basis for what it promotes. “I like the credibility of having compassionate physicians and scientists reaching as many people as possible to educate them,” she said. Kim believes that if people become more aware of how animals are treated, many will want to work toward change. “That is what I try to do as I go about my everyday life—to inform people and motivate them to speak out for animals and try to bring about changes.” Kim and Robert began supporting PCRM in 1989. “We were probably among the first people ever to join,” Kim said. “I remember when my husband and I were back in Washington, D.C., many years ago—I think it was not terribly long after Neal started PCRM—we wanted to meet him and see what he was like and what the organization that we were supporting was doing, so we made an appointment and went to see him and his offices, which were small, and he only had a small staff. But he was very gracious, he showed us around, and he gave us a book,” she recalled with a smile. “When we left, my husband asked what I thought, and I told him that I thought Neal was very personable and would be a good voice for the animals. My husband agreed and said, ‘I think he will do very well.’ My husband had very good judgment!” Kim said. PCRM Wants Your Vehicle! D onating your car, truck, or RV to PCRM is not only tax-deductible but it is also a great way to support all of our programs. Contact V-DAC (Vehicle Donation Any Charity) at 1-866-332-1778 and let them know you wish to contribute to PCRM and they will make arrangements to pick up your vehicle. If you have questions or need more information, please contact Brian Halprin at bhalprin@ pcrmfoundation.org. Member Update from Dr. Neal Barnard O n May 10, we held our first “President’s Update” conference call for Stewards, President’s Circle members, and Lifetime Partners. Dr. Barnard gave an update to members on PCRM’s activities, including the breaking news story about our victory with the dairy industry lawsuit. Members who participated in the call had the opportunity to ask questions and interact with fellow PCRM supporters. The feedback was so positive that we will continue to schedule regular conference call updates throughout the year. To learn more about the benefits of being a Steward, President’s Circle member, or a Lifetime Partner, please contact Craig Ziskin, associate director of annual giving, at 202686-2210, ext. 374. Summer 2007 GOOD MEDICINE 19 PCRM Marketplace PCRM Marketplace Research Issues What Will We Do If We Don’t Experiment on Animals? Medical Research for the 21st Century C. Ray Greek, M.D., and Jean Swingle Greek, D.V.M. The Greeks answer the title’s question with a tour of truly modern medical research. With advances in the study of human genetics and the ability to measure human responses to drugs at the molecular level, researchers will find it increasingly difficult to justify the crude data accumulated from animal experimentation. 262 pgs, $24.99 Pleasurable Kingdom Animals and the Nature of Feeling Good Jonathan Balcombe, Ph.D. Life as experienced by animals is not a grim struggle for survival, according to animal behavior researcher Balcombe. He presents persuasive evidence that animals—like humans—find enjoyment in touch, food, aesthetics, companionship, anticipation, and more. Full of insight and humor, the book poses vital ethical questions. 256 pgs, $24.95 Health and Nutrition NEW LANDMARK BOOK FROM PCRM Nutrition Guide for Clinicians Physicians Committee for Responsible Medicine This comprehensive medical reference manual covers nearly 100 diseases and conditions, including risk factors, diagnoses, and typical treatments. Most importantly, it provides the latest evidence-based information on nutrition’s role in prevention and treatment. Includes an in-depth examination of general nutrition, macronutrients, micronutrients, and nutritional requirements for all stages of life. 884 pgs, $19.95 Special Discount $17.95 Your Vegetarian Pregnancy A Month-by-Month Guide to Health and Nutrition Holly Roberts, D.O., F.A.C.O.G. Fulfilling every nutritional guideline recommended by the American College of Obstetrics and Gynecology, this book is the first authoritative guide to maintaining a healthy plant-based diet before, during, and after the birth of your child. 378 pgs, $15.00 20 Summer2007 2007 GOOD MEDICINE Summer Dr. McDougall’s Digestive Tune-Up John A. McDougall, M.D. Dr. McDougall takes a candid, humorous look at how the digestive tract functions. Learn how a low-fat, cholesterol-free, plant-based diet can prevent and cure constipation, hemorrhoids, IBS, and other chronic intestinal disorders. 211 pgs, $19.95 New! Food Allergy Survival Guide Vesanto Melina, M.S., R.D., Jo Stepaniak, M.S.Ed., Dina Aronson, M.S., R.D. Three prominent authorities in nutrition and vegetarian cooking explain how to pinpoint foods that trigger allergies and aggravate conditions such as arthritis, asthma, ADHD, and depression. Learn to recognize“hidden” culprits in prepared foods. Discover delicious, healthful substitutes. Includes over 100 recipes. 383 pgs, $19.95 The Best in the World Fast, Healthful Recipes from Exclusive and Out-of-the-Way Restaurants Neal D. Barnard, M.D., Editor This popular collection of wonderfully healthy recipes comes from the world’s best and most unusual restaurants. Enjoy these vegan delicacies at home. Hardcover, 71 pgs, $11.95 Super Size Me DVD Directed by Morgan Spurlock In this award-winning documentary, filmmaker Spurlock lives on a McDonald’s-only diet for one month, with devastating results. Mixing humor with commentary by medical experts, Super Size Me exposes the consequences of the national romance with fast food. 96 minutes, plus bonus footage and interviews. Parental advisory: language, graphic medical scenes. $26.99 Don’t Eat This Book Fast Food and the Supersizing of America Morgan Spurlock Funny, optimistic, and fact-packed, this book presents the backstory of Super Size Me. It also details how the fast-food industry endangers health in the United States, often with the cooperation of government. 320 pgs, $21.95 The Great American Detox Diet Alex Jamieson NOW IN PAPERBACK! Morgan Spurlock’s vegan chef fiancée presents the detox program that undid the damage caused by his monthlong, nothing-but-McDonald’s diet. Jamieson’s eight-week program includes nearly 90 recipes that eliminate animal products, sugar, caffeine, and potential allergens. 288 pgs, $14.95 An educationally enhanced Super Size Me DVD package for grades 6–12 is available from www. SuperSizeMeStore.com. Healthy Eating for Life book series from PCRM PCRM’s series of medically sound, reader-friendly books explain diet’s role in wellness and disease prevention. Each book includes at least 80 healthy, delicious vegetarian recipes. Forewords by PCRM president Neal D. Barnard, M.D. Healthy Eating for Life for Children PCRM with Amy Lanou, Ph.D. When children learn proper nutrition early in life, they are more likely to avoid heart disease, obesity, and diabetes. Here’s how to get them started. Includes kid-tested recipes. 258 pgs, $14.95 Healthy Eating for Life for Women PCRM with Kristine Kieswer Learn how the right foods can ease menstrual and menopausal symptoms, strengthen bones, encourage weight loss, protect the heart, and help prevent certain cancers. 260 pgs, $14.95 Healthy Eating for Life to Prevent and Treat Cancer PCRM with Vesanto Melina, M.S., R.D. This book provides a complete nutrition program to prevent and fight cancer. Packed with tips and guidelines for lifelong good health. 244 pgs, $14.95 Healthy Eating for Life to Prevent and Treat Diabetes PCRM with Patricia Bertron, R.D. Studies show that diabetes can be highly responsive to diet and lifestyle changes. PCRM explains these changes and how to put them into practice. 244 pgs, $14.95 PCRM Marketplace From Neal D. Barnard, M.D., PCRM president Dr. Neal Barnard’s Program New! for Reversing Diabetes I f you have diabetes or are concerned about developing it, this program could change the course of your life. Dr. Barnard’s groundbreaking clinical studies, the latest funded by the National Institutes of Health, show that diabetes responds dramatically to a low-fat, vegetarian diet. Rather than just compensating for malfunctioning insulin like other treatment plans, Dr.Barnard’s program helps repair how the body uses insulin. Includes 50 delicious recipes. 288 pgs, $25.95 Breaking the Food Seduction We all have foods we can’t resist, foods that sabotage our health. But banishing those cravings for chocolate, cookies, cheese, or burgers isn’t a question of willpower, it’s a matter of biochemistry. Drawing on his own research and that of other leading institutions, Dr. Barnard reveals how diet and lifestyle changes can break the craving cycle. 324 pgs, $14.95 Breaking the Food Seduction Audio Summary by the author, 68 mins, compact disc, $10.00 Turn Off the Fat Genes Genes, including those that shape our bodies, actually Becoming Whole: The Story of My New! Complete Recovery from Breast Cancer Meg Wolff, Foreword by T. Colin Campbell Eight years after losing a leg to bone cancer, Meg Wolff was dying of breast cancer. Conventional treatments were not expected to save her life, but Meg fought back with a macrobiotic diet and a determination to control how she would live or die. Discover Meg’s story of physical and emotional healing and how it could apply to your life. 288 pgs, $21.00 Appetite for Profit Michele Simon Law professor and health food policy expert Michele Simon exposes manipulation of consumers and government by fast-food, beverage, and processed-food corporations. The result is a national epidemic of obesity , heart disease, and diabetes. Fascinating and empowering reading. 416 pgs, $15.95 Don’t Drink Your Milk Frank Oski, M.D. Milk is the perfect food—for a calf. For humans, however, adapt to outside influences. Dr. Barnard explains the process and provides a three-week gene-control program complete with menus and recipes by Jennifer Raymond. Here are powerful tools for achieving long-term weight loss and better health. Paperback, 350 pgs, $14.00 A Physician’s Slimming Guide for Permanent Weight Control You can succeed in becoming and staying slimmer! This book is not a diet—it’s a comprehensive program that takes the reader beyond artificial“formula approaches.” 96 pgs, $7.95 Foods That Fight Pain Did you know that ginger can prevent migraines and that coffee sometimes cures them? Drawing on new research, Dr. Barnard shows readers how to soothe everyday ailments and cure chronic pain with common foods. 348 pgs, $14.00 Foods That Fight Pain VHS video, 55 mins, $14.95 Food for Life The breakthrough book on aging, heart disease, cancer, weight control, and general health. Preface by Dean Ornish, M.D. Loads of tips on changing your diet, 21 days of menus, plus delicious recipes by Jennifer Raymond. 334 pgs, $14.00 milk poses several health risks, as outlined in this very readable book by the former director of the Johns Hopkins University Department of Pediatrics. 92 pgs, $9.95 The Whole Foods Diabetic Cookbook Patricia Stevenson, Michael Cook, Patricia Bertron, R.D. It’s not just about sugar anymore! A low-fat, vegetarian diet high in fruits, vegetables, whole grains, and beans will keep blood sugar at a more constant level and help control excess weight.Delicious recipes make it easy.Includes background info on diabetes and nutrition. 159 pgs, $12.95 More Great Good Dairy-free Desserts—Naturally Fran Costigan Chef-instructor Fran Costigan teaches the fine art of creating vegan pastries, pies, cakes, puddings, and frozen desserts. Everyone from novice bakers to gourmet cooks will find valuable tips on equipment, techniques, and all-natural ingredients. 221 pgs, $19.95 Vegan Microwave Cookbook Nancy Berkoff, R.D. Award-winning chef and columnist Nancy Berkoff offers over 165 easy recipes, many of which take less than 10 minutes to prepare. Microwave magic can make dream meals mesh with a busy schedule. 287 pgs, $16.95 From The Cancer Project The Nutrition Rainbow Poster The more naturally colorful your meal is, the more likely it is to have an abundance of cancer-fighting nutrients. Pigments that give fruits and vegetables their bright colors represent a variety of protective compounds. The Nutrition Rainbow poster shows the cancer-fighting and immuneboosting power of differenthued foods. 17”x22”, $6.00 Prescription for Life Poster This whimsical work of art introduces your patients to the importance of fruits, vegetables, whole grains, and beans in cancer prevention and survival. It also tells how to obtain free information about nutrition, recipes, and classes from The Cancer Project. 17”x22”, $6.00 The Survivor’s Handbook: Eating Right for Cancer Survival Find out how foods fight cancer and the advantages of a high-fiber, low-fat, dairyand meat-free diet. Includes updates from the latest research, special prostate and breast cancer sections, tips for making the dietary transition, and recipes. Spiral bound, 145 pgs, $14.95 Eating Right for Cancer Survival video This groundbreaking new video is designed to work hand-in-hand with the companion Survivor’s Handbook. Together they’ll provide you with empowering information on how simple, everyday choices can cause major changes in your health and well being. Contains eight presentations by Neal Barnard, M.D., Jennifer Reilly, R.D., and Amy Lanou, Ph.D. 103 mins. DVD $14.95 VHS $14.95 Special Video /Handbook Combo Offer DVD / Handbook $24.95 VHS / Handbook $24.95 Summer 2007 GOOD MEDICINE 21 PCRM Marketplace From PCRM Fat-Free and Easy Great Meals in Minutes! Jennifer Raymond As guest chef for Dr. Dean Ornish’s “Open Your Heart” program, Jennifer Raymond has the secret to making quick, fat-free, scrumptious, vegan recipes that will delight everyone. 152 pgs, $12.95 Choose Health! Four Food Groups Poster Striking color photos illustrate PCRM’s New Four Food Groups for complete nutrition without cholesterol and excess fat. Includes serving recom mendations. 22"x17", $6.00 Cartoon Four Food Groups Poster PCRM’s colorful and informative guide to nutritional recommendations, illustrated for younger eaters. Vegetarian Starter Kit It’s all here. Learn about the power of a plant-food diet for fighting disease and maintaining a healthy weight. Get the facts on vegan diets for pregnant women, babies, and children. Try delicious sample recipes. Debunk common myths. And make friends with the New Four Food Groups! 16 pgs, $2.00 Go Veg—B4 It’s 2L8 Quality 100% cotton. Yellow on forest green. $11.95 22"x17", $6.00 Guía de Iniciación para una Dieta Vegetariana New Four Food Groups The Spanish-language version of PCRM’s popular Place Mats Vegetarian Starter Kit. $2.00 Four colorful guides to the New Four Food Groups. The flip side provides cooking and food stor- Show your support for humane research with Humane Charity Seal of Approval Items Go Vegan Multilingual Apron Veg-friendly phrases in ten languages. 21"x 28" gourmet apron with pocket. Cream on forest green. $13.95 Refrigerator Magnet Full color, 2"x3½". $1.00 Bumper Sticker Full color. $1.00 please print PCRMMarketplace Item Color (If applicable) ORDER FORM Size–M,L,XL (If applicable) Qty.Price NAME Subtotal ADDRESS (Please include street address for UPS service.) CITY STATE ZIP COUNTRY DATE DAYTIME PHONE Send check or money order payable to PCRM, or use your credit card. Sorry, no C.O.D.’s. CARD NUMBER VISA MC EXPIRATION DATE CARDHOLDER SIGNATURE Shipping and handling Charges For orders shipped to more than one address, please add shipping for each additional address. Orders within the United States Shipping via U.S. Postal Service or UPS. For orders between $1 and $20 = $5 For orders between $20 and $40 = $7 For orders between $40 and $70 = $9 For orders between $70 and $100 = $12 For orders more than $100 = $15 22 International and Express Shipping Orders: Shipping charges vary depending on country and/or express shipping method. Call for charges: 1-800-695-2241 2007 GOOD MEDICINE Summer Winter 2006 SUBTOTAL SHIPPING AND HANDLING Residents of CA, DC, MA, and MI please add applicable sales tax. Shipping charge to additional addresses TOTAL (U.S. dollars only) Mail to: PCRM Marketplace P.O. Box 180 Summertown, TN 38483 (Do not use the membership envelope in this issue.) 1-800-695-2241 Or order online at: www.pcrm.org Or call toll-free: ©photodisc Just the Facts PCRM Illustrations/doug Hall Crematoriums Feel the Heat From Obesity Expanding waistlines in the United Kingdom are forcing many crematoriums to enlarge their furnaces to accommodate larger coffins. Most standard furnaces, which fit coffins 16 to 20 inches, are too narrow to fit the wider coffins, which now go up to 40 inches to accommodate bigger bodies. Vegan Burgers Sell Like Hot Cakes When meatless burgers made their debut on the lunch menu at Newport Harbor High School in California’s Newport-Mesa Unified School District, they sold out within minutes and left students asking for more. Newport Harbor is the first school in this district to offer vegan options at lunchtime. Egypt’s Disappearing Frog The dissection industry in Egypt is taking a massive toll on the Egyptian common frog, a population of amphibians whose numbers are rapidly dwindling. A random survey conducted among students from science fields showed that the average Egyptian student dissects 14 to 17 frogs each year. Estimates show that 1.5 million frogs are collected annually for dissection purposes. About 10 percent of these frogs suffocate to death in storage containers. All of Egypt’s science-related fields require animal dissection. Poo Dun It? Federal and California state officials are blaming last year’s nationwide E. coli outbreak in spinach on cattle manure from the Paicines Ranch in San Benito County. Manure from the ranch, which is near a spinach field leased by Mission Organics, was contaminated with E. coli, the main species of bacteria living in the intestinal tracts of animals. Animal intestines are the natural source of E. coli infections. Just the Facts If You’re Happy and You Know It, Wag Your Tail… to the Right Researchers in Italy report that dogs wag their tails to the right side when they feel fundamentally happy or positive about someone or something. When dogs experience negative or fearful feelings, they wag their tails to the left. Some researchers had argued that only humans show brain asymmetry. Slam Dunk Vegan Diet Atlanta Hawks basketball star Salim Stoudamire traded in his junk-food, meat-based diet for a vegan one last June. Feasting on grilled tofu, quinoa, and plenty of fruits and vegetables, Stoudamire’s new diet gives him the endurance to play hard, and he often leads his team in scoring. Swiss Company Goes Fish-Free A Swiss company derives the omega-3 fatty acids EPA and DHA from algae instead of fish oil. The company is working with the Food and Drug Administration to gain approval as a new dietary ingredient in the United States. Omega-3 fatty acids are available from many plant sources, and the human body can convert EPA to DHA on its own. No TV Time for Fruits and Vegetables The Henry J. Kaiser Family Foundation reports that 40 percent of commercials aimed at children promote unhealthy foods, including candy, snacks, and fast food. Children ages 8 to 12 see the most of these commercials—about 21 per day. The number of television advertisements for healthy fruits and vegetables? Zero. Vegetarian Diets: Taste Great, Less Expensive Vegetarians in the Netherlands can now enroll in “VegePolis,” the world’s first discounted health insurance plan for people on a meatless diet. Created by insurers Agis Zorgverzekeringen and Stichting Preventie, the plan operates on the principle that vegetarians are healthier than meat-eaters. The eating habits of these policyholders will be tracked and compared with their carnivorous counterparts. Summer 2007 GOOD GOOD MEDICINE MEDICINE Winter 2006 23 PCRM Physicians Committee for Responsible Medicine 5100 Wisconsin Ave., NW, Suite 400 Washington, DC 20016 Non-Profit Org. U.S. Postage PAID Random Lake, WI Permit #1 Address Service Requested Physician Profile Gordon Saxe M.D., Ph.D. Innovative Research on Diet and Prostate Cancer W hen Gordon Saxe was just out of college, his father was diagnosed with advanced cancer. In searching for a way to help, Dr. Saxe met and interviewed cancer survivors who had experienced remissions of their cancers after adopting plant-based diets, stress reduction, and other healthy lifestyle changes. Fascinated by what he had witnessed, he embarked on a lifelong journey of discovery that took him to both graduate school and medical school. Along the path, he shared much of what he had learned with his father. “Dad remained incredibly op- timistic, adopted some of my suggested changes, and lived many years longer than his doctors had predicted,” Dr. Saxe said. During a period when Dr. Saxe’s father was particularly strict about his diet, he even experienced a remission of the cancer (confirmed by biopsy). “His experience is one of the reasons I’m so passionate about this topic and optimistic about its potential for patients,” Dr. Saxe added. A faculty member at the University of California, San Diego, School of Medicine, Dr. Saxe has been conducting groundbreaking research on the power of a plant-based diet—in combination with body-mind techniques such as meditation, yoga, and t’ai chi—in controlling the spread of prostate cancer. He is also examining the role that a plant-based diet may play in altering how genes work to trigger cancer growth. “It’s exciting to see how much control people can gain over their health by making simple changes in their diets and lifestyles. It’s also extremely gratifying to know that this work is helping to answer the perplexing questions about the nature of malignancy,” Dr. Saxe said. Dr. Saxe spoke about the effects of plant-based diets on disease progression in prostate cancer at The Cancer Project’s 2006 Cancer and Nutrition Symposium and PCRM’s 2007 Nutrition in Clinical Practice continuing medical education seminar, and he has been answering reader’s questions about diet and cancer in his “Ask the Doctor” column in The Cancer Project News for the past year. YOU’LL BE SHOCKED! With postage, printing, and handling expenses, each returned copy of Good Medicine costs PCRM almost $2. Over the year, this adds up to thousands of lost dollars. If your address has changed, please let us know promptly. 24 [email protected] or 202-686-2210, ext. 304 GOOD MEDICINE Summer 2007 printed on recycled paper
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