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HAONIllH[ 42 OTQU1ruoq.wUe; XaTU Tllv xaTUTa~11 TOUe;, (~'nH!OOLOUe; UJTUAAllAOUe; XaTU Tllv aQXlXl1 EVTa~ll TOUe; OTOV XAa 00 XaL OTQaTEUIJ.EVOUe;. ABSTRACT E~iraaq JTTVtAWV The epidemiologic elevation of tuberculosis be gins at the 16 th century and reaches the 18 th century, while the decrease continues until today and it is predicted to cover also the nnd century in USA and Europe. Today tuberculosis has become the most important communicable disease in the world. The World Health Organization (WHO) estimates that tuberculosis has infected the one-third of the world population, while in developing countries the infec tion of tuberculosis reaches the two-thirds of the world population. In 1996, 8 million new cases of tubercu losis were marked with 3 million deaths per year since 1990. Clinical features, radiology sputum examination, control of sensitivity in anti-tuberculosis drugs and specific tuberculosis skin reaction accomplish the research and diagnosis of tuberculosis. The suspen sion of contamination and infection is achieved at a high percentage by chemoprophylaxis and BCG vac cination. The control and prevention of the infection of tuberculosis tends to be a severe problem. The aims of controlling and preventing tubercu losis include the detection and treatment of the cases and the suspension of the development of the infec tion. Tuberculosis should be continuously kept un der control on a national level in different commu nity groups (age, sex and ethnic origin) in order to avoid the appearance of more resistant cases. In that way is ensured that appropriate progress is being made and more suitable control measures are being redirected. yla b-Koch H E~ETaOll mUEAWV Yla b-Koch yLVETaL IJ.E UIJ.EOO JTaQaOXE1Ja0IJ.a 11 XaAAlEQYEla UYQWV. Ta UTOIJ.a IJ.E 8EUXU mUEAa OTO UIJ.EOO JTaQaOXEUa0IJ.a aJTOTEAOUV Tllv XUQ La JTllYl1 IJ.OAUVOlle;2.28.62. H IJ.0AUVOll XaL VOOllQOTllTa OTO JTEQl~UAAOV TOU cpuIJ.aUXOU ELVaL JTOAAaJTAUOlEe; aJTO OU ELVaL 01'0 yE VlXO JTA1l8u0IJ.0. 0 cpullauXOe; 15-20 llIJ.EQEe; IJ.ETU Tllv EvaQ~ll Tlle; 8EQamLae; IJ.E Ta aUYXQova aVTlcpuIJ.aTl xu cpuQIJ.axa JTQaxTlxu OEV IJ.ETaOLOEl 1'11 vooo. LE au TO O1JIJ.~UAAEl 11 E~a08EVllOll XaL IJ.ELWOT] TOU aQl8IJ.ou TWV IJ.UXO~aXTllQlO[WV IJ.a~[ IJ.E EAanwOT] TOU ~l1xa XaL Tlle; aJTOXQEIJ.'ljJ1le;49. (/JVllUTlVOavTilJeaaq H aVLxvEuOll Tlle; cpUIJ.aTLWOlle; IJ.E CPUIJ.aTlVOaVTL oQaOT] EXEl EcpaQIJ.oYl1 IJ.OVO OE XWQEe; IJ.E XaIJ.llAO OEL XTll cpwaTlwOOUe; IJ.0AUVOlle; XaL OJTOU OEV EXEl EcpaQ IJ.OOTEl IJ.a~lXU TO BCG 2. ~) EJlPOA.laaJl6~ JlE BeG To BCG JTQEJTEl va EcpaQIJ.O~ETaL OE 000 yLvETaL IJ.lXQOTEQll llAlxLa. XOQllYELTaL EVOOOEQIJ.lXU OTllv JTE QlOXl1 Tlle; EXq:JUOT]e; TOU aQlOTEQoU OEATOElOOUe; OE MOT] 0,1 ml OE JTaLOlU UVW TOU ETOUe; XaL 0,05 ml (IJ.lo1l M OT]) OE JTaLOlU XUTW TOU ETOUe;. EJtaVEIJ.~OALaOIJ.Oe; JTQE JTEl va axoAou8EL OTllV llAlxLa TWV 6 ETWV. 0 EJTavEIJ. ~OAlaOIJ.Oe; 8EWQELTaL aJTaQaLTllTOe;, OlOU IJ.E TOV OEU TEQO Ef.l~oAlaOIJ.O Ta JTaLOlU XaAUmOVTaL IJ.EXQl Tllv 11 AlxLa TWV 20 ETWV. LTOUe; EVl1AlXEe; 11 EcpaQIJ.oYl1 TOU BCG JTEQLOQ~ETaL OE OIJ.UOEe; aU~llIJ.EvOU XlVOUVOU, OJTWe; TO VOooxolJ.Elaxo ~ EQyaOTllQlaxo JTQOOWJTlXO IJ.E aQvllTlxl1 Mantoux2. Avtl<pul!unxo 3tQoYQUl!l!u Ol ~aOlXEe; aQXEe; TOU aVTlcpUIJ.aTlXOU JTQoYQUIJ. IJ.aTOe; ELVaL: 1. AVLxvEUOll VEWV JTEQlJTTWOEWV 2. KaA118EQaJTELa 3. EIJ.~oAlaoIJ.Oe; IJ.E BCG Ta aJTOTEAE0IJ.aTa TOU aVTlcpUIJ.aTlX01J JTQoYQuIJ. IJ.aTOe; EXTlIJ.WVTaL aJTo Tle; IJ.ETa~oMe; TWV olacpoQwv EJTlOlllJ.lOAOYlxwv OElXTWV XaL lOLa[TEQa aJTo Tllv EJTl mwoll Tlle; vooou XaL TOV ET1l0LO x[vOuvo IJ.OAUVOT]e;. H EXQ~wOll Tlle; CPUIJ.aT[WOlle; 8a 8EWQ1l8E[ OU EXEl EJTl TEUX8EL oTav OTllv llALx[a TWV 14 ETWV 11 8EuxoTllTa Tlle; Mantoux ELVaL ALYOTEQll aJTo 1%. llonidis G. Approaching tuberculosis. Hippo kratia, 2002, 6(1): 31-44 BIBAIOrPAcI»IA 1. Balasubramanian V, Wiegeshaus EH, Taylor BT, Smith DW. Pathogenesis of tuberculosis: Pathway to apical localization. Tuber Lung Dis 1994,75:168-80 2. Leitch AG. Tuberculosis: Pathogenesis epidemiol ogy and prevention. In: Crofton and Douglas (ed): Respiratory Diseases. 5th ed, Blackwell Science, 2000, pp.476-506 3. Leading A. The global chal1enge of tuberculosis. Lan cet 1994,2:277-79 4. Dolin PJ, Raviglione MC et al. Global tuberculosis incidence and mortality during 1990-2000. Bul1 World Health Organization 1994,72:213 5. Styblo K. The potential impact of AIDS in the tu berculosis situation in developed and developing countries. Bul Int Un Ag Lung Dis 1988,63:25-30 6. Tobin JM. Tuberculosis Lung Infection, In terstitial Lung Disease and Socioeconomic issues in AJRCCM rnnOKPATEIA 2002, 6, I 2001. Am 1 Respir Crit Care Med 2002,165:631-41 7. WHO. Tuberculosis control as an integral part of primary health care. Geneva 1988 8. Murray lE. 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N Engl 1 Med 1995,332:92-98 62. Tobin 1M. Tuberculosis lung infections and in inter stitial lung disease in AJRCCM 2000. Am 1 Respir Crit Care Med 2001,164:1774-1788 AM1JAoyearp{a. r. HAoVLtJll~ ~l']~oxQmLa~ 53 552 36 rraY6Qa~a eWOaAOYLXl'] Con-esponding author. Illonidis G, 53, Dimokratias str. 552 36 Panorama Thessaloniki-Greece
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