Annual Report 2011 - The University of Chicago Medicine
Transcription
Annual Report 2011 - The University of Chicago Medicine
today’s Science … tomorrow’s Standard of Care 2 0 1 0 – 2 0 11 A n n u a l R e p o r t At t h e F o r e f ro n t o f D i s c ov e ry® A UCCCC 2010-2011 Annual Report CONTENTS A Message from the Director 1 Excellence in Science Translates to Excellence in Care 2 + Grants Fund Groundbreaking Research Opportunities + Top-Notch Technology Advances Basic and Clinical Science + More Patients Have Access to UChicago Cancer Care + Expanded Community Outreach Efforts Help Underserved Chicagoans Report from the Cancer Registry 16 + Cancer Program Recognized for Quality, Innovation, and Excellence + A Focus on Leukemia The University of Chicago Cancer Research Foundation 24 + Commitment to Cancer Research Remains Steadfast + Foundation Again Raises Over $2 Million for Cancer Research + UCCRF Boards + Honor Roll of Donors + Financial Report A Look Ahead 40 The University of Chicago Comprehensive Cancer Center (UCCCC) is one of 40 National Cancer Institute (NCI)-designated Comprehensive Cancer Centers and one of two in Illinois. The NCI designation recognizes scientific excellence, as well as discovery and development of effective approaches to cancer risk assessment, prevention, diagnosis, treatment, and survivorship. The designation also recognizes a cancer center’s accomplishments in educating healthcare professionals and the public, as well as its outreach to underserved populations. At the UCCCC, we have earned a national and international reputation of quality, innovation, and commitment to addressing cancer from every angle. B cancer.uchicago.edu A Message from the Director Reflecting upon this past year, we have seen much progress in our efforts to develop personalized cancer treatments that not only target a patient’s genetic makeup, but also target a tumor’s genetics and behavior. This individualized approach provides better outcomes and economic efficiency. As treatments become even more customized early 1970s made leukemia the first cancer and individualized, cancer research will become for which personalized therapeutics became more diversified and collaborative, requiring a possible. Today, our work in leukemia continues global team of experts capable of understanding to foster the development of novel therapies. cellular processes at a much finer level. Cancer researchers will work more closely with physicists, chemists, and biostatisticians who can analyze very large, complex data arrays. Researchers will also collaborate with economists who will help us understand the economic impact of cancer. Although much of our financial support comes from external sources including the National Institutes of Health and the American Cancer Society, another large portion comes from passionate philanthropists. We sincerely thank all of our donors who have provided the seed The new UCCCC strategic plan acknowledges money and other support that have resulted in our strengths in the scientific and clinical arenas much larger government grants, as well as new and takes into account the changing landscape program development and faculty recruitment. of cancer research. Our goals over the next few years will focus on three key areas: ++ Cancer risk assessment and prevention With 12 million cancer survivors in the United States, it is imperative that we remain diligent in our commitment to excellence ++ Individualized therapies and innovation so that today’s science can ++ Cancer survivorship, economics, and outcomes become tomorrow’s standard of care. As you read the following pages, you will get a glimpse at some of the very exciting With heartfelt gratitude, advancements that we have made this past fiscal year. You will also learn about new programs and partnerships that will make our superior cancer care available to an even wider audience. This year, we dedicated a portion of our annual report to the Leukemia Program (See Page 19). Groundbreaking work at UChicago in the 1 Michelle M. Le Beau, PhD Arthur and Marian Edelstein Professor of Medicine UCCCC Director UCCCC 2010-2011 Annual Report Excellence in Science Translates to Excellence in Care This year, our annual report focuses on how our efforts transform today’s science into tomorrow’s standard of care. Utilizing the collective expertise of 225 members from six integrated scientific programs, the UCCCC focuses on understanding the many complex issues related to cancer risk, prevention, diagnosis, treatment, and survivorship. Personalized medicine is a primary focus of the UCCCC. One day, physicians will be able to use a series of markers unique to each person to tailor individualized prevention and treatment strategies. These markers could include genetic, social, environmental, and behavioral factors. Center for Personalized Therapeutics Some personalized treatments already exist in oncology. They include genetic tests and protein measurements to identify the appropriate treatment strategies for patients with breast, lung, and colorectal cancer. Mitchell Posner, MD Peter O’Donnell, MD Ya-Chen Tina Shih, PhD In 2010, The University of Chicago (UChicago) opened a Center for Personalized Therapeutics, directed by Mark Ratain, MD, the Leon O. Jacobson Professor of Medicine and UCCCC associate director for clinical sciences. The center is now recruiting patients in a first-of-its-kind study that incorporates broad genetic information into routine clinical practice for medical treatment decisions. Such information could allow physicians to predict which patients are most likely to respond positively to a given medication, experience severe side effects, or require alternative dosing. The study, named “The 1200 Patients Project,” is led by Peter O’Donnell, MD, assistant professor of medicine. The new project complements work by the UChicago Committee on Clinical Pharmacology and Pharmacogenomics, chaired by M. Eileen Dolan, PhD, professor of medicine. Pharmacogenomics is the study of how genetic variants affect a patient’s response to drugs. 2 Initiative in Economics of Cancer Another first-of-its-kind program is the new Initiative in the Economics of Cancer, led by Ya-Chen Tina Shih, PhD, associate professor of medicine. By uniting cancer researchers with experts from the social sciences, Dr. Shih’s group aims to weigh the costs and benefits of new technologies so that patients receive the best, most logical care. “The burden of cancer and cost of cancer care are among the most important challenges facing the U.S.,” said David Meltzer, MD, PhD, associate professor of medicine and director of the Center for Health and the Social Sciences. “The University of Chicago’s strength in economics and cancer and its rich tradition of interdisciplinary research make it an ideal place for the development of this program.” Patient Navigation Program To help facilitate the sometimes intimidating task of coordinating initial appointments with multiple specialists, The University of Chicago Medical Center (UCMC) launched the Central Intake and Navigation program in early 2011 for its cancer patients. “Our patients deserve an efficient system in which they can learn about their disease, understand it, review their options, and develop a plan,” said Mitchell Posner, MD, Thomas D. Jones Professor and Vice-Chair of Surgery. “For many patients, a cancer diagnosis is a life-defining moment.” The program quickly produced positive results. The average wait time for appointments decreased from 13.8 calendar days at the beginning of the fiscal year to 10.1 calendar days by summer 2011, with a significant movement toward appointments in 7 days or less by fall of 2011. cancer.uchicago.edu Personalized medicine is a primary focus of the UCCCC. One day, physicians will be able to use a series of markers unique to each person to tailor individualized prevention and treatment strategies. Grants Fund Groundbreaking Research Opportunities Before cancer treatment options ever reach the clinic, UCCCC researchers spend months— or more likely years—analyzing many intricate details about a cancer’s biology and behavior. are studying how transfer RNAs work as biomarkers and regulators of gene expression in breast cancer. The science needed to stimulate significant transformation from bench to bedside requires a significant investment. New discoveries would not be possible without grants from the government, industry, and the private sector. Computer-Aided Diagnosis of Prostate Cancer with Multiparametric MR Imaging Aytekin Oto, MD, associate professor of radiology, and his research team are developing a pilot computer-aided diagnosis (CAD) system for detecting prostate cancer using magnetic resonance (MR) imaging. This new method will provide a noninvasive way to differentiate between high-risk and low-risk prostate cancers and will help standardize the analysis of MR results. With these advantages, the CAD/MR imaging technology may help more than a million American men who undergo prostate biopsies each year. This fiscal year, our investigators were involved with more than 600 funded projects totaling about $110 million. The projects were supported through grants from the National Institutes of Health (NIH) and its institutes, including the National Cancer Institute (NCI), as well as the American Cancer Society (ACS), The University of Chicago Cancer Research Foundation (UCCRF), Cancer Research Foundation (CRF), and other private foundations. The following grant projects were among those funded in fiscal year 2010-2011: Synergy of Radiation and Immunotherapy: New Approaches Transfer RNAs as Biomarkers and Regulators of Gene Expression in Breast Cancer Marsha Rosner, PhD, director and Charles B. Huggins Professor of the Ben May Department for Cancer Research, and colleagues are conducting genomic research to identify the key genes responsible for forming breast cancer. In particular, they Aytekin Oto, MD Maciej Lesniak, MD 4 Marsha Rosner, PhD Yang-Xin Fu, MD, PhD, professor of pathology, and colleagues are establishing new strategies to reduce original tumor size while boosting immunity for the destruction of cancer cells that have spread to other parts of the body. By studying the underlying workings of the immune system, the researchers aim to develop a novel, Marc Bissonnette, MD cancer.uchicago.edu Yang-Xin Fu, MD, PhD New discoveries would not be possible without grants from the government, industry, and the private sector. (Left) Patrick Wilson, PhD, MS highly effective treatment approach combining radiation therapy with immunotherapy for various phases of cancer, including metastases. EGFR-VDR Signals in Diet-Promoted Inflammation and Cancer Marc Bissonnette, MD, associate professor of medicine, and his research team are investigating the connection between a Western-style, high-fat diet and the development of colon cancer. Building on previous research, the investigators aim to uncover how the epidermal growth factor receptor (EGFR) and vitamin D signaling pathways interact to affect the influence of dietary fat on colonic inflammation and tumor risk. These studies will identify potential new therapeutic targets for colon cancer, the third leading cause of cancer-related deaths in the U.S. Neural Stem Cell-Based Virotherapy for Malignant Glioma Maciej Lesniak, MD, professor of surgery and director of neurosurgical oncology and neurooncology research, and colleagues are developing a novel approach, called virotherapy, for the treatment of malignant brain tumors. The team will use neural stem cells to carry a virus, specially developed to attack cancer cells, directly to the malignant brain tumor. They hypothesize that this targeted technique will be more effective than injecting the virus into the tumor. A researcher works in the Le Beau hematology/oncology research lab in the Knapp Center for Biomedical Discovery. 6 cancer.uchicago.edu Top-Notch Technology Advances Basic and Clinical Science To make cancer research more cost-efficient and to help provide the most technologically advanced equipment possible, the UCCCC offers researchers access to shared technologies supported through our NCI Cancer Center Support Grant. The Core Facilities include 12 mature facilities and one developing facility opened in 2011. The new Epidemiology and Research Recruitment Core (ERRC) provides expertise in study design, patient recruitment, and data collection to help researchers more efficiently conduct studies to observe cancer patterns within different patient populations. “It’s kind of a ‘one-stop shop,’” said Scientific Director Brian Chiu, PhD. “We coordinate systematic and rigorous specimen collection as well as implement processes for large-scale collection of interview data to ascertain individual variables and exposure history. The integration of these multiple dimensions allows investigators to conduct high-quality multidisciplinary population and clinical research studies.” State-of-the-Art Technologies Keeping up with advances in lab equipment, software, and other technologies is extremely important as cancer research delves deeper into the complex study of cellular and molecular mechanisms that contribute to tumor development. “The best tools make for the best science,” said Vytas Bindokas, PhD, co-technical director of the Integrated Microscopy Core Facility. Several of the core facilities received funding this year to update or expand their offerings: ++ The Integrated Microscopy Core acquired three new major systems that represent the best in corrected optics, with advanced features that allow for high speed and sensitivity. Modern-day advanced optics help solve new mysteries, including why some cancer cells behave differently than others. ++ The Genomics Facility purchased new systems to conduct next-generation sequencing with the high-throughput capacity for genotyping and gene expression arrays. These systems offer the fastest technology available for sequencing genetic information, which will help researchers find associations between specific gene variants and disease. ++ The Human Tissue Resource Facility has implemented a new biospecimen banking database and a new digital pathology image analysis system to accelerate basic and clinical research. The space itself will soon undergo renovations to improve workflow and allow for expanded storage of specimens. Prototype Breast Imaging System Innovative technologies have the potential to change medical practice. A prototype breast imaging computer workstation, created by radiology professor Maryellen Giger, PhD, and members of her research team, could soon revolutionize the way breast cancer is diagnosed. The intelligent breast workstation for computer-aided diagnosis (CADx) and quantitative image analysis reviews data from multimodality images and helps evaluate and characterize suspicious lesions. Fused PET/CT image using radiotracers that will soon be produced on campus. Dr. Giger said she is excited to see the technology move one step closer to clinical implementation, “I see CADx translating to the clinical setting in Test sample captured with a new highpowered light microscope. 7 UCCCC 2010-2011 Annual Report Maryellen Giger, PhD, and her research team created a prototype breast imaging computer workstation that could revolutionize the way breast cancer is diagnosed. the near future as another ‘test result’ to be used concurrently by radiologists in improving the accuracy of diagnostic output and patient management.” only help to find more accurate ways to apply radiation therapy, but will also allow researchers to assess the effectiveness of gene therapy. Cyclotron Particle Accelerator The cyclotron purchase was made possible, in part, by a 2011 donation from the William F. O’Connor Foundation, named for a legendary figure in Chicago financial circles who had a strong personal belief in the quality of care at UChicago. Our institution will be the only academic medical center in Illinois with a cyclotron. Research capabilities will be greatly enhanced when a cyclotron is installed on campus in 2012. A cyclotron is a particle accelerator that generates radioisotopes used in diagnostic imaging. Imaging at the molecular level provides a noninvasive way to monitor and assess a patient’s response to treatment. Radioisotopes will not 8 cancer.uchicago.edu More Patients Have Access to UChicago Cancer Care The UCCCC, with its team of talented clinical and laboratory scientists, is making great strides in helping cancer patients live longer and lead better quality lives. Very soon, this high level of cancer care and expertise will reach even more patients in a new state-of-the-art building. Construction of the New Hospital Pavilion (NHP) is expected to be completed in 2012, with the first patients admitted in early 2013. The NHP is poised to be one of the most leading-edge hospitals in the world. The building’s flexible design will enhance collaboration and interaction among physicians, as well as allow the hospital to adapt easily to new technologies. The 10-story, 1.2 millionsquare-foot building will span two city blocks and will connect to Comer Children’s Hospital and the outpatient Duchossois Center for Advanced Medicine (DCAM). An entire floor will be devoted exclusively to the care of cancer patients. In spring 2012, another newly constructed cancer facility will be unveiled, outside The University of Chicago’s Hyde Park campus. The two-story outpatient cancer treatment center will be located about 39 miles southwest of downtown Chicago in New Lenox, Ill., as part of a partnership between the UCMC and Silver Cross Hospital. The University of Chicago Cancer Center at Silver Cross will offer academic medical center specialists in a community hospital setting to serve patients who normally would have to travel far distances to obtain the cancer services they The University of Chicago Cancer Center at Silver Cross will open in 2012 in New Lenox, Ill. 9 UCCCC 2010-2011 Annual Report The New Hospital Pavilion will offer 240 private patient rooms, all on the upper levels and each with a spectacular view of the city. need. Patients will have access to physicians, chemotherapy infusion services, radiation therapy, cancer support groups, preventative screenings, and a comprehensive resource center. The new center will also have a top-of-the-line linear accelerator for image-guided radiation therapy that provides the safest and most accurate results. Access to Cancer Clinical Trials Silver Cross cancer patients will also have access to cancer clinical trials. The UCCCC has the largest cancer clinical trials program in Illinois and is one of only a few institutions in the country to provide all three phases of clinical trials through NCI-funded programs. In 2010, approximately 900 patients were enrolled in cancer therapeutic trials. These trials focused on the study of new drugs, stem-cell transplantation, and multidisciplinary treatments. Patient enrollment is under way for more than 350 cancer clinical trials at the UCCCC. To see a complete list, visit our new website, which was launched in August 2010. Go to cancer.uchicago. edu and click on Search Clinical Trials in the blue box, or call toll-free 1-855-702-8222 for adult trials or 1-773-702-6808 for pediatric trials. Cancer Resource Center to Expand The Cancer Resource Center (CRC) will get a makeover later this year. The CRC, which is a partnership between the UCCCC and the ACS, is located on the first floor of DCAM. Staffed by a licensed professional counselor and a certified health education specialist, the CRC 10 provides cancer patients and their families with information that helps make the treatment process easier—everything from one-on-one counseling, to access to cancer literature and cosmetic services. In fiscal year 2010-2011, CRC staff met with nearly 3,000 patients, including 816 new patients. “Most patients really need help with transportation and the financial burden it creates,” said CRC Program Manager Mary P. Herbert, BSS, CHES. “This past fiscal year, thanks to private donations to ACS, we were able to provide those in need with $37,000 in transportation assistance including parking passes, Chicago Transit Authority passes, and Pace Paratransit Service passes. We are one of only a few sites in the country that provides this type of service.” More than a dozen support groups are also offered, including a new support group that was launched in July 2011. The Cancer Networking Group for Women of Color meets on the second Wednesday of the month on the fourth floor of DCAM. In 2012, the new CRC offices will be part of a more spacious patient waiting area. The larger footprint will allow for private waiting spaces in an aesthetically pleasing, open floor plan. Cancer patient navigators will be located in the same area to help patients coordinate and streamline their experience. “The private areas will help us do more oneon-one counseling and will make patients more comfortable when they need services, such as a wig fitting,” added Herbert. cancer.uchicago.edu Expanded Community Outreach Efforts Help Underserved Chicagoans Encouraging people to live healthier lifestyles and to understand the benefits of cancer screening are two priorities for the UCCCC Office of Community Engagement and Cancer Disparities (OCECD). As the office celebrated its first anniversary in August 2011 under the direction of Karen E. Kim, MD, MS, it also marked substantial progress in developing relationships with Chicago’s underserved communities—including the black, Asian, Hispanic, and Native American communities. OCECD staff met with more than 7,000 people this past fiscal year through 36 community events, ranging from national and regional healthcare symposia, to family wellness nights, to a Powwow at Navy Pier. Many cancer topics were addressed, although the primary focus for the office’s first year was breast cancer. These relationships were strengthened through strategic partnerships with various units within UChicago, as well as with community- and faith-based organizations. “One out of every three cancer diagnoses in American women is breast cancer, and we’ve found that the breast cancer death rate is much 11 UCCCC 2010-2011 Annual Report Pritzker School of Medicine students helped administer cancer screening surveys and flu shots in the Asian community in December 2010. higher in Chicago than in New York City or in the U.S. as a whole. We need to change that,” said Dr. Kim, associate professor of medicine. built an infrastructure to address the cancer disparities facing Asian Americans,” said AHC Executive Director Edwin Chandrasekar. ENRICH’D Program Community Health Educators In early 2011, the OCECD launched the innovative Empowering Neighborhood Resources in Combating Health Disparities (ENRICH’D™) program, designed to increase awareness about cancer screening, treatment, and access to healthcare resources. With input from The University of Chicago Pritzker School of Medicine students, as well as community members, programs are adapted to the unique characteristics of each neighborhood to help close gaps in healthcare knowledge and encourage healthier lifestyles. The Asian community is also benefitting from a strategic partnership between the OCECD and the Chinese American Service League (CASL). Using resources from an NCI Cancer Center supplement grant for Community Health Educators, several hundred homecare workers participated in discussions—primarily in Cantonese—about the benefits of breast cancer screening and the resources that are available in the community. “If you have community members who speak the language and who look like the community, they can deliver a very powerful message that will motivate behavioral change,” said Dr. Kim. ENRICH’D kicked off in the Roseland community, a predominantly black neighborhood on Chicago’s South Side, and was highlighted by a breast cancer forum held at the South Shore Cultural Club in June. Nearly 200 people attended, and more than 50 people registered for free mammography services. ENRICH’D, funded in part by a grant from Exelon Corporation, will expand this fall into the Asian community in the Armour Square neighborhood. A solid partnership with the Asian Health Coalition (AHC) is helping to increase participation in OCECD activities. “Being a partner with the OCECD has been an empowering experience. Under the leadership of Dr. Kim, I am excited that the OCECD has Karen E. Kim, MD, MS, hosts an ED-U-CATE session at the Chinese American Service League. 12 ED-U-CATE Program The OCECD is also offering a workplace wellness program designed to educate small groups of employees about cancer risk, prevention, screening, treatment options, and clinical trials. The Everyone Developing an Understanding of Cancer Awareness, Treatment, and Education (ED-U-CATE) program launched in February 2011. By mid-year, the program was presented to more than 150 people within UChicago, CASL, Chicago Urban League, and PepsiCo. In fall 2011, ED-U-CATE will be presented at Catholic Charities and Chicago Public Schools. Cancer Transitions Program A grant from the LIVESTRONG™ foundation helped the OCECD prepare to become one of the nationwide hosts of Cancer Transitions™, a program that helps cancer patients through the transitional period following cancer treatment. The program includes sessions on nutrition, exercise, stress reduction, medical management, and quality of life. The first series began in August 2011 on Chicago’s South Side. Woodlawn Charter School students visited UChicago in March to learn about careers in the medical field, including community outreach. cancer.uchicago.edu (Top) An outreach event in Chinatown provided participants with glaucoma and diabetes screenings, in addition to gathering data about cancer knowledge. (Bottom left) Tanya Kimber from the American Cancer Society and Fornessa Randal from the UCCCC helped distribute cancer information during a breast cancer event. (Bottom right) About 200 women attended a breast cancer forum at the South Shore Cultural Center. 13 UCCCC 2010-2011 Annual Report UCCCC Welcomes 15 New Members Our accomplishments this past year would not have been possible without the 225 dedicated scientists and clinicians composing the UCCCC cancer research team. In fiscal year 2010-2011, we welcomed more than a dozen new members. They are: 14 Eric Svensson, MD, PhD Associate Professor of Medicine > Peter O’Donnell, MD Instructor of Medicine > Victoria Villaflor, MD Assistant Professor of Medicine < Brandon Pierce, PhD Assistant Professor of Health Studies < Yoav Gilad, PhD Associate Professor of Human Genetics (not pictured) Joshua Hemmerich, PhD Assistant Professor of Medicine > Michael Spiotto, MD, PhD Instructor of Radiation and Cellular Oncology < Jennifer McNeer, MD Assistant Professor of Pediatrics < Daniel Catenacci, MD Instructor of Medicine < Jill de Jong, MD, PhD Assistant Professor of Pediatrics > Ya-Chen Tina Shih, PhD Associate Professor of Medicine > Vani Konda, MD Instructor of Medicine > Issam Awad, MD, MSc Professor of Surgery > Iris Romero, MD Assistant Professor of Obstetrics and Gynecology > Patrick Wilson, PhD, MS Assistant Professor of Medicine > cancer.uchicago.edu UCCCC Members Earn National Honors The many honors—local, national, and international—bestowed on our scientists and clinicians reflect the high caliber of their work and the significant contributions they are making to patient care. The following is a small sample of their distinguished achievements: Nancy Cox, PhD Member-at-Large, Section on Biological Sciences, American Association for the Advancement of Science (AAAS) Thomas Gajewski, MD, PhD President, Society for Immunotherapy of Cancer (SITC) Karen E. Kim, MD, MS Member, NIH Advisory Committee on Research on Women’s Health Michelle M. Le Beau, PhD Inaugural Arthur and Marian Edelstein Professor of Medicine Kay Macleod, PhD Member, NIH Cancer Molecular Pathobiology Study Section 15 Elizabeth McNally, MD, PhD President, American Society for Clinical Investigation (ASCI) Mitchell Posner, MD President, Society of Surgical Oncology (SSO) Bruce Minsky, MD Educator of the Year, Association of Residents in Radiation Oncology (ARRO) / American Society for Radiation Oncology (ASTRO) Mark Ratain, MD American College of Clinical Pharmacology (ACCP) Honorary Fellow Award Olufunmilayo Olopade, MBBS ACS Distinguished Service Award and Member, National Cancer Advisory Board Xiaochuan Pan, PhD Chair, NIH Biomedical Imaging Technology Study Section Carrie Rinker-Schaeffer, PhD President, Metastasis Research Society (MRS) Mark Siegler, MD American Society for Bioethics and Humanities (ASBH) Lifetime Achievement Award UCCCC 2010-2011 Annual Report Cancer Program Recognized for Quality, Innovation, and Excellence The University of Chicago Medical Center (UCMC) cancer program gained ground in the 2011-2012 U.S. News & World Report annual Best Hospitals survey. The #14 ranking is one position higher than the previous survey and keeps the UCMC as the #1 ranked cancer program in Illinois. The rankings are based on a mathematical formula that takes into account factors including expected mortality, actual mortality, technology, patient services, and patient volume. The cancer program also earned a top accreditation from the American College of Surgeons (ACoS) Commission on Cancer (CoC). The 3-year accreditation with commendation symbolizes excellence, innovation, and a broad spectrum of cancer research and patient care services offered locally, nationally, and internationally. “We are honored to receive such a high rating,” said UCCCC Director Michelle Le Beau, PhD. “For our patients, this means they can expect to receive quality, comprehensive care that includes a multidisciplinary team approach, a complete range of state-of-the-art services and treatments, and access to early detection programs, cancer education, and support services.” Led by Kevin Roggin, MD, chair of the Cancer Committee, and assisted by Cassie Simon, CTR, assistant director of the UCCCC Cancer Registry, the cancer program underwent an intensive, onsite CoC survey in May 2011. As part of this triennial process, members of the Cancer Committee provided detailed information about their departmental resources, policies, and processes that ensure high-quality, multidisciplinary, cancer care is available and provided to our patients. Our Cancer Program received commendation in seven key areas: ++Outcomes analysis ++Quality of National Cancer Data Base (NCDB) data submission ++College of American Pathologists (CAP) guidelines ++Clinical trials accrual ++Prevention and early detection ++Cancer education for registry staff ++Cancer-related quality improvement 16 cancer.uchicago.edu Table 1: 2010 Cancer Cases by Site Primary Site Newly Diagnosed Recurrent/ Progressive Disease Total % of Total Digestive System 563 65 628 18.50% Male Genital System 496 72 568 16.80% Breast 308 38 346 10.20% Respiratory System 286 47 333 9.80% Urinary System 242 42 284 8.40% Endocrine System* 173 25 198 5.80% Female Genital System 149 28 177 5.20% Oral Cavity & Pharynx 127 34 161 4.70% Lymphoma 112 26 138 4.10% Brain & Other Nervous System** 99 20 119 3.50% Leukemia 97 28 125 3.70% Miscellaneous*** 59 10 69 2.00% Skin Excluding Basal & Squamous 49 19 68 2.00% Myeloma 43 5 48 1.40% Soft Tissue 40 12 52 1.50% Mesothelioma 40 7 47 1.40% Bones & Joints 21 3 24 0.70% Kaposi Sarcoma 3 0 3 0.10% Eye & Orbit 1 2 3 0.10% 2,908 483 3,391 100.00% Total * Includes benign pituitary tumors ** Includes benign neoplasms ***Includes blood dyscrasias, myelodysplastic syndromes, and myeloproliferative disorders Cancer Registry Provides Vital Research Data 2010 UCMC Cancer Data The Cancer Registry annually reviews more than 50,000 UCMC medical records to identify patients diagnosed and/or treated for cancer or a benign central nervous system neoplasm. A specialized oncology database record is created for each cancer patient that includes age, gender, diseasespecific characteristics, treatment, annual followup, and outcomes. An abstract or “snapshot” is created for each patient’s disease experience. In 2010, 3,391 patients were diagnosed and/or treated at the UCMC for a malignancy or benign central nervous system neoplasm. (See Table 1) Throughout the year, the registry receives requests from physicians, researchers, administrators, and other medical staff for specific or aggregate data that will be used to improve patient care—whether it is to generate prevention strategies, to advance technologies for screening, diagnosis, and treatment, or to develop survivorship programs. In the past fiscal year, the Cancer Registry fulfilled 60 data requests for projects including clinical research, health disparities research, outcomes research, cancer program development, grant proposals, and community outreach activities. 17 Cancer Incidence by Type Of these, 2,908 (86%) were newly diagnosed patients and 483 (14%) had recurrent or progressive disease. The most frequently seen cancers were of the digestive system (628), which includes colorectal cancer; male genital system (568), which includes prostate cancer; breast (346); respiratory system (333), which includes lung cancer; and urinary system (284), which includes kidney cancer. Patient Demographics More than half of all patients (1858, 54.8%) were diagnosed with cancer between the ages of 50 and 69 years. When reviewing the data by gender, women tended to be diagnosed at a younger age than men (50–59 years vs. 60–69 years respectively). (See Figure 1) UCCCC 2010-2011 Annual Report Distribution by gender (See Figure 2) reveals a higher number of male patients (1,849, 54.5%) than female patients (1,542, 45.5%), and distribution by race shows our patient population is predominately white (2,103 patients, 62%), followed by black (871 patients, 25.6%) and Hispanic (146 patients, 4.3%). Patient Geographics An analysis of a patient’s residence or county at initial diagnosis (See Diagram 1) illustrates that a majority of patients (2,671, 79%) seen in 2010 were Illinois residents, with the highest number residing in Cook County (1,740 patients, 65.1%) followed by DuPage County (244 patients, 9.1%), Will County Figure 1: 2010 Cancer Cases by Gender and Age at Diagnosis (207 patients, 7.7%), Lake County (148 patients, 5.5%) and Kane County (59 patients, 2.2%). Nearly one quarter (21%, 720 patients) of our total cancer patient population lived outside of Illinois, coming primarily from the neighboring states of Indiana (550 patients, 76.3%), Michigan (56 patients, 7.7%), and Wisconsin (27 patients, 3.7%). We also served 18 international patients from countries including Israel (4 patients), Mexico (3 patients), United Arab Emirates (3 patients), China (2 patients), Brazil (1 patient), Canada (1 patient), Panama (1 patient), Poland (1 patient), Romania (1 patient), and Saudi Arabia (1 patient). Figure 2: 2010 Cancer Cases by Gender, Race/Ethnicity 700 1,500 600 1,200 500 900 300 Number of cancer cases Number of cancer cases 400 200 100 0 0-29 Male 30-39 40-49 50-59 60-69 70-79 80-89 90+ Female 600 300 0 White Black Male Hispanic Asian Female Asian Unknown Indian or Pakistani, NOS Diagram 1: 2010 Patient Residence at Diagnosis Illinois Residents by County Non-Illinois Residents 1,740 (65.1%) Cook 550 (76.3%) Indiana 59 (2.2%) Kane 56 (7.7%) Michigan 148 (5.5%) Lake 2,671 (79%) 720 (21%) 27 (3.7%) Wisconsin 207 (7.7%) Will 18 (1%) Outside of U.S.: Israel, Mexico, United Arab Emirates, China, Brazil, Canada, Panama, Poland, Romania, and Saudi Arabia 244 (9.1%) DuPage 18 cancer.uchicago.edu A Focus on Leukemia As personalized medicine moves within reach in many specialties, leukemia was the first cancer for which personalized therapeutics became possible—and it has its roots at UChicago. Pioneering work by scientists including Janet D. Rowley, MD, DSc, James W. Vardiman, MD, Harvey M. Golomb, MD, Richard A. Larson, MD, Michelle M. Le Beau, PhD, and Michael J. Thirman, MD, helped uncover the biology and heterogeneity of leukemias that paved the way for biologically targeted treatments, including tyrosine kinase inhibitors (e.g., imantinib, nilotinib, dasatinib), which are now standard treatment for chronic myeloid leukemia (CML). Dr. Larson was a key investigator in the pivotal clinical trials that led to approval of these groundbreaking therapies. The seminal event came in 1972 when Dr. Rowley discovered that some forms of leukemia are triggered by a translocation of two different chromosomes. This breakthrough confirmed a genetic basis for cancer and earned Dr. Rowley countless awards, including the prestigious Lasker-DeBakey for Clinical Medical Research Award, National Medal of Science, and Presidential Medal of Freedom. Current Highlights Since Dr. Rowley’s breakthrough, the leukemia group at UChicago has continued to characterize genetic changes for several key forms of acute and chronic leukemia, providing insights that are leading to the development of novel therapies. For example, Dr. Le Beau is currently the principal investigator of a project involving Dr. Larson, Kenan Onel, MD, PhD, and others to understand more about the development of therapy-related myeloid neoplasms—leukemias that develop as a result of successful chemotherapy or radiotherapy for other malignancies, such as lymphoma or breast cancer. “During the past decade, we have learned a great deal about the dysregulation of genes that are involved in various leukemias. We have also learned, in many cases, which patients will 19 respond well to certain treatments and which patients will not,” explained Wendy Stock, MD, professor of medicine and co-leader, with Dr. Thirman, of the UCCCC Hematopoiesis and Hematological Malignancies Program. One area of current interest to the UChicago leukemia group is the study of epigenetic modifications and abnormalities that occur in leukemia. Epigenetic studies examine factors, such as abnormal DNA methylation and structural modifications in chromatin, that deregulate normal gene expression and promote cancer development. Lucy Godley, MD, PhD, Olatoyosi Odenike, MD, and colleagues are trying to understand what causes epigenetic dysregulation in acute myeloid leukemia (AML) and related malignancies, and they are working to develop therapies to reprogram abnormal gene expression in malignant cells. Based on these insights, our leukemia clinicians have designed novel clinical trials to evaluate the efficacy of these approaches for patients with leukemias that are resistant to more traditional chemotherapy. Improving cure rates using hematopoietic cell transplantation is another important research focus. Andrew Artz, MD, and Amittha Wickrema, PhD, are working to improve access to this curative approach for a broader range of patients—those who are older, who may not have a traditional sibling donor, and for those with high-risk biological features who might not otherwise be eligible to receive a transplant. Along with new faculty recruit Hongtao Liu, MD, PhD, the leukemia transplant group has recently completed a novel study demonstrating the feasibility of using hematopoietic cells from an immunologically half-matched donor combined with an umbilical cord donation to successfully transplant patients with high-risk leukemias. UCCCC 2010-2011 Annual Report Dysplastic megakaryocytes in myelodysplastic syndrome “Dwarf” megakaryocytes (brown) and Gaucher cells (pink) in chronic myeloid leukemia “We are a very committed group,” said Dr. Stock. “We are not satisfied with the current therapies. We have a team of people who will work with each patient to optimize their treatment to get the best results.” From Research to Practice (Seated, from left) Dorothy Sipkins, MD, PhD, Wendy Stock, MD, Olatoyosi Odenike, MD, Paula Del Cerro, RN, Peggy Green, RN, and Jane Churpek, MD. (Standing, from left) Gordana Raca, MD, PhD, Carol White, APN, Todd Zimmerman, MD, Katherine Breitenbach, RN, Nitin Jain, PhD, Hongtao Liu, MD, PhD, Thomas Wickert, Michael Daunov, Andrew Artz, MD, Jean Ridgeway, APN, Richard Larson, MD, Michelle Le Beau, PhD, and Michael Thirman, MD. (Not Pictured) John Anastasi, MD, John Cunningham, MBBCh, MSc, Jerome Dickstein, MD, PhD, Lucy Godley, MD, PhD, Sandeep Gurbuxani, MBBS, PhD, Elizabeth Hyjek, MD, Jennifer McNeer, MD, Kenan Onel, MD, PhD, James Vardiman, MD, and Howard Weiner, CRA. Abnormal megakaryocytes in myelodysplastic syndrome with isolated del(5q) Michael J. Thirman, MD Our researchers are involved in leukemia trials at a national level through National Cancer Institute-sponsored cooperative groups. Dr. Larson has chaired the Leukemia Committee for the Cancer and Leukemia Group B (CALGB) for the past 15 years. The committee performs clinical and biological studies that have led to improved standards of care for leukemia patients. Dr. Stock is spearheading a CALGB trial that may improve the standard of care for young adults with acute lymphoblastic leukemia (ALL). The trial stemmed from insights provided by another UChicago leukemia clinician, James Nachman, MD, a beloved colleague and international leader in pediatric leukemias, who passed away in June 2011. Ten years ago, Drs. Stock, Larson, and Nachman performed a retrospective analysis that led to the observation that young adults (ages 16-20 years) with ALL, who were treated on pediatric trials, had significantly better survival rates than patients of the same age who were treated for ALL in adult cooperative group trials. This finding prompted Dr. Stock and others to develop new clinical approaches to treat this group of patients. “We are trying to find out if the success rate is tied to the pediatric treatment regimen, the patients, doctors, or the support system,” said Dr. Stock, who explained that these young patients are usually on their own without family members to help them during a treatment process that takes several years. Dr. Stock said that one way UChicago will begin to support these patients is through a focused, young adult oncology clinic that will be developed in conjunction with pediatric colleagues at Comer Children’s Hospital, including Jennifer McNeer, MD, and John Cunningham, MBBCh, MSc. 20 UChicago currently has about 40 open adult and pediatric leukemia clinical trials. These and other clinical trials have formed the basis for many scientific breakthroughs and continue to enhance our ability to diagnose and treat the disease. A sample of leukemia and transplant research by UChicago faculty published during fiscal year 2010-2011 includes: Arsenic Trioxide Improves Event-Free and Overall Survival for Adults with APL Including arsenic trioxide in consolidation therapy (therapy given after a cancer has disappeared following initial treatment) is safe and improves event-free, disease-free, and overall survival for adults with newly diagnosed acute promyelocytic leukemia (APL). The findings, by Drs. Larson, Stock, and other members of five North American cooperative groups including CALGB, were derived from a 3-year study involving 481 patients. (Powell et al., Blood 116:3751-3757, 2010) Real-time Pharmacokinetics Helps Improve Success of Hematopoietic Cell Transplantation Allogeneic hematopoietic cell transplants are known to prolong life and occasionally cure patients with advanced hematologic malignancies; however, disease recurrence remains high. A multidisciplinary UChicago team, including Peter O’Donnell, MD, and Koen van Besien, MD, launched a phase I study to learn if real-time pharmacokinetics (the study of how a drug is absorbed, when drug action begins, how long it is effective, etc.) could help guide more effective administration of busulfan when this chemotherapy drug was used as part of a transplant conditioning strategy. The researchers found that adjusting dosage based on real-time pharmacokinetics resulted in improved drug efficacy and tolerability. A phase II study is under way. (O’Donnell et al. Leukemia & Lymphoma 51:2240–2249, 2010) Novel TP53 Cancer Susceptibility Mutation Uncovered Whole-genome sequencing of a patient with no other known cancer susceptibility genes revealed cancer.uchicago.edu Leukemia Stats The American Cancer Society (ACS) predicts that nearly 45,000 new cases of leukemia will be diagnosed in 2011. ACS also predicts that 21,780 people will die from the disease in 2011. New Technology Advances Individualized Treatments for AML and Myeloid Neoplasia Two articles in a special issue of Seminars in Oncology, devoted to Personalized Cancer Treatment and authored exclusively by UChicago faculty, focused on how new technology, such as next-generation, high-throughput DNA sequencing, is advancing individualized therapies for leukemia. In one paper, Drs. Godley, Le Beau, and colleagues wrote, “The vision for the future entails an integrated and automated approach to these analyses, bringing the possibility of formulating an individualized treatment plan within days of a patient’s initial presentation.” The second paper, by Dr. Odenike and colleagues described how new technology will rapidly and more comprehensively identify gene mutations and epigenetic alterations in individuals Figure 3: UCMC Newly Diagnosed Leukemia Patients, 2006-2010 Number of newly diagnosed patients with myeloid neoplasia. “The hope is that our ever-expanding knowledge of the molecular genetics of myeloid neoplasia, coupled with the increasing availability of molecularly targeted drugs, will allow personalized, genotype-specific therapy to come of age in the 21st century.” (Godley et al., Semin Oncol 38:215-224, 2011 and Odenike et al., Semin Oncol 38:196-214, 2011) a novel gene variant that could be a key to understanding early onset cancer. The patient had no family history of cancer but developed breast and ovarian cancer in her late 30s. She subsequently developed therapy-related AML (t-AML). The patient tested negative for the BRCA1 and BRCA2 mutations. Dr. Le Beau was among the researchers who found a non-inherited deletion in the TP53 gene, which encodes the p53 tumor suppressor protein. “This case highlights the utility of whole-genome sequencing to identify clinically relevant germline genetic abnormalities contributing to cancer susceptibility,” they wrote. (Link et al., JAMA 305:1568-1576, 2011) 150 100 50 At The University of Chicago Medical 2006 2007 2008 2009 2010 Center (UCMC), the number of newly diagnosed leukemia patients remained relatively stable from 2006 to 2010. (See Figure 3) Treatment year In 2010, 125 total patients (74 male, 51 female) were treated for leukemia at the UCMC. (See Figure 4) The largest number of patients (30, 24.0%) were aged 60–69 years, followed by 29 (23.2%) aged 50–59 years, and 23 (18.4%) aged 0–29 years. Figure 4: 2010 All Leukemia Cancer Patients by Gender and Age 40 35 30 Most leukemia cases (82, 65.6%) were characterized as myeloid and monocytic leukemia, followed by 39 cases (31.2%) as lymphocytic leukemia, and four cases (3.2%) as other leukemia. (See Table 2) 25 20 Table 2: 2010 Leukemia CASES BY Type, Gender, and Class Total Male Female Newly Diagnosed Recurrent/ Progressive Disease Myeloid & Monocytic Leukemia 82 48 34 66 16 Acute Myeloid Leukemia 59 36 23 45 14 Acute Monocytic Leukemia 3 2 1 3 0 Chronic Myeloid Leukemia 18 10 8 16 2 2 0 2 2 0 Lymphoid Leukemia 39 23 16 28 11 Acute Lymphoblastic Leukemia 20 11 9 13 7 Chronic Lymphocytic Leukemia Other Myeloid/Monocytic Leukemia 16 9 7 12 4 Other Lymphocytic Leukemia 3 3 0 3 0 Other Leukemia 4 3 1 3 1 Other Acute Leukemia 3 2 1 2 1 Aleukemic, Subleukemic & NOS Total Leukemia Cases 21 1 1 0 1 0 125 74 51 97 28 UCCCC 2010-2011 Annual Report Number of patients 15 10 5 0 0-29 40-49 60-69 80-89 30-39 50-59 70-79 90+ Age Range Male Female Personalized Therapeutics Improve Outcomes for Leukemia UCCCC researchers are working tirelessly to identify genetic pathways involved in hematologic malignancies, such as leukemia, because by understanding and characterizing these pathways, we are able to develop novel, molecularly targeted treatments. Patients from the Chicago area and beyond know that when they come to The University of Chicago for treatment, they will receive the unique expertise and leading-edge treatment strategies that have made our hematologic malignancies program a program of distinction for pediatrics, as well as for adult patient care. Novel Treatment Approach Helps Teen Swimmer Dive Back in Pool Kris Egebrecht knew something was wrong when Brandon, her teen who loves to swim, could not get out of bed. “I slept for 15 hours a day for 3 days straight,” Brandon said. Kris took him to an urgent care clinic near their home in Northwest Indiana and was convinced a blood test would reveal a diagnosis of mononucleosis, a viral illness common in teens. Instead, Brandon tested positive for acute myeloid leukemia (AML). While Kris grappled with what she called her “worst nightmare,” Brandon’s primary care physician set the wheels in motion for Brandon’s treatment. With an aggressive disease like AML, time is of the essence. treatment plan. The drug clofarabine, which is effective in patients with relapsed AML, was administered as the first cycle of induction therapy, followed by four cycles of standard chemotherapy. “The goal of this study is to achieve better remission rates by using this more intense drug as part of the initial therapy for newly diagnosed patients,” explained Jennifer McNeer, MD, assistant professor of pediatrics. Overcoming Setbacks Brandon’s first treatment was the most challenging. He developed tumor lysis syndrome, which occurs when chemotherapy very quickly breaks down leukemic cells, explained Dr. McNeer. It caused Brandon’s kidneys and lungs to fail. Dr. McNeer said Brandon’s care team worked together to support him until his kidneys resumed their normal function. Kris said she was impressed with how Brandon’s care team explained every step of the treatment to the family, “They answered questions before I even knew I had questions.” Brandon’s pediatric oncologist referred him to UChicago’s Comer Children’s Hospital, where Brandon was diagnosed with a genetic subtype of AML that was first described at UChicago in 1983 by Michelle M. Le Beau, PhD, and colleagues. Brandon was enrolled in an innovative clinical trial affiliated with St. Jude Children’s Research Hospital in Memphis, Tenn., that utilized an aggressive (From left) Mary Paterik, RN, Brandon Egebrecht, and his mom, Kris 22 cancer.uchicago.edu Brandon’s treatment ended earlier than initially planned because studies have demonstrated that four cycles of chemotherapy are as effective as five, according to Dr. McNeer. “Survival rates in AML are certainly better than they were years ago, but we are always working to improve them,” she said. “It’s great we were able to offer Brandon a unique treatment protocol.” Brandon was diagnosed with leukemia in April 2011. By August, his treatment was completed and he began his junior year of high school. “I’ve grown a lot from this experience,” Brandon said. “It has definitely changed my perspective.” Stem Cell Donation Saves Life of Adult AML Patient Another success story in AML revolves around a woman whose life was forever altered by a stranger. In May 2007, Amelia (Amy) Vittetoe was feeling tired and thought her thyroid medication needed adjusting. But after extensive blood and bone marrow studies confirmed a diagnosis of AML, she was immediately admitted to a local hospital near her home in Crystal Lake, Ill. An attending physician suggested that Vittetoe transfer to a hospital that was better equipped to treat her disease. She considered several Chicago area hospitals, but chose UChicago, a decision that she said saved her life. “That was the farthest hospital that we could have gone to, but I know for sure that it was the best,” she said. Vittetoe’s multidisciplinary care team, including Wendy Stock, MD, professor of medicine, used molecular diagnostics to reveal that Vittetoe had the same cytogenetic abnormality as Brandon Egebrecht. This particular subtype of leukemia is usually associated with a relatively good prognosis with standard chemotherapy. A Setback Forces a New Approach Just 2 weeks after completing her treatments, Vittetoe’s leukemia relapsed and a stem cell transplant was recommended. “Even with specific subsets of leukemia, there’s a lot of heterogeneity,” Dr. Stock said. “We still have a lot to learn about why some cases like Amy’s relapse and require a transplant whereas others are cured with standard chemotherapy.” None of Vittetoe’s relatives was a match, but she found a perfect match through the national bone marrow registry. After undergoing more chemotherapy to control her disease, Vittetoe was admitted for her stem cell transplant where she received intensive chemotherapy followed by the intravenous infusion of stem cells from an unrelated donor––a 41-year-old man from Germany. Three years later, Vittetoe is still in remission and has new priorities. She now works as a school nurse and spends as much time as possible with her children. She has also become active in the national marrow donor program. “I can’t donate stem cells or bone marrow to anyone anymore because of my condition, but I can help someone else find a match,” she said. Dr. Stock said cancer researchers are currently looking closer at these leukemias to see whether certain new targeted therapies, in addition to chemotherapy, will improve their outcome. “We take each case individually and tailor the therapy as best we can using the most sophisticated diagnostic and therapeutic strategies available,” Dr. Stock said. “If specific chemotherapeutic options don’t work, then immune therapies like transplants can work, and Amy is a perfect example of that.” Vittetoe’s treatment kept her in and out of the hospital and required frequent visits to the outpatient clinic for blood transfusions. She also participated in a national clinical trial and received additional chemotherapy. “It was, for sure, the most difficult time of my life,” Vittetoe said. “The hardest part was being away from my kids.” 23 Jennifer McNeer, MD Amy Vittetoe and her family UCCCC 2010-2011 Annual Report Wendy Stock, MD The University of Chicago Cancer Research Foundation Commitment to Cancer Research Remains Steadfast We’d like to extend our sincerest thanks to everyone who has donated their time, talent, and treasure to The University of Chicago Cancer Research Foundation this past year. You have once again demonstrated your unwavering commitment to raising money for cancer research. Because of your support over the years, we have been able to develop new tools and technologies that are helping us understand more about the complexities of cancer. We have made progress in areas, such as molecular diagnostics, proteomics, and epigenetics, and in creating individualized therapies for many types of cancer. With your continued support, our researchers will make new discoveries that will help advance cancer prevention, diagnosis, treatment, and survivorship. Mary Ellen Connellan Executive Director The University of Chicago Cancer Research Foundation Ruth Ann Gillis McGuinnis President, Board of Trustees The University of Chicago Cancer Research Foundation Foundation Again Raises Over $2 Million for Cancer Research For the 6th consecutive year, The University of Chicago Cancer Research Foundation (UCCRF) has raised more than $2 million for cancer research. Thanks to dedicated staff, very active volunteers, and generous donors, the $2.2 million raised in fiscal year 2010-2011 will be used to fund 30 major basic and clinical research projects that align with the UCCCC’s strategic plan focus areas—cancer risk assessment and prevention, individualized therapies, and cancer survivorship and economics. The following are among the UCCCC researchers receiving Foundation grants this fiscal year: ++ Samuel Volchenboum, MD, PhD, MS, who is performing novel work studying 24 protein production and interaction (proteomics) in neuroblastoma, a cancer that develops in immature nerve cells and affects mainly infants and children. ++ Ya-Chen Tina Shih, PhD, who will direct a new Initiative in Cancer Economics and whose research examines the diffusion of new and existing medical technologies in cancer, cancer disparities, and the associated health and economic consequences. ++ Donald Vander Griend, PhD, who discovered that prostate cancer stem cells express a cancer.uchicago.edu number of genes that are normally expressed only in embryonic stem cells. If further research shows that these genes promote malignancy or hormone-resistant therapy, new treatments can be developed to target gene behaviors. About Us The UCCRF comprises four boards—one governance board (Board of Trustees) and three fundraising boards (Women’s Board, Auxiliary Board, and Associates Board). The three fundraising boards host a variety of activities throughout the year from an elegant Cancer Ball, to a “Spring Forward” social, to a “Cocktails for a Cure” event. Additional fundraising is accomplished through motivated third parties, including Kuhlman’s Krusaders, Arlington Million Ladies, and Midway Aquatics Club. These passionate volunteers are part of what we are now calling “Team Cancer,” organizations and individuals helping us support cancer research. Corporate funding, including a grant from Exelon, helps UCCCC community outreach programs (See Page 12). The UCCRF became part of the Celebrated Chefs program in fall 2010. When a participant dines at one of the many Celebrated Chefs restaurants in the Chicago area using an enrolled credit card, 5% of the bill is donated to the UCCRF. Prestigious Shubitz Prize The 2011 Simon M. Shubitz Cancer Prize and Lectureship was awarded to Charles L. Sawyers, MD, from Memorial Sloan-Kettering Cancer Center in New York City, for his research findings that have led to new, targeted treatments for prostate cancer. After meeting with UChicago faculty and medical students and delivering the noontime lecture, “Overcoming Resistance to Targeted Therapy,” Dr. Sawyers was honored at a dinner reception at the Gleacher Center in downtown Chicago, which was attended by more than 100 people. During the event, Walter Stadler, MD, and William Dale, MD, PhD, provided updates on their research in prostate cancer. In 2012, the Shubitz Prize will be awarded to Joe Gray, PhD, an internationally renowned cancer and genomics researcher who developed a test that has transformed how treatments are selected for breast cancer patients. He chairs the Department of Biomedical Engineering at Oregon Health & Science University (OHSU) and is director of the OHSU Center for Spatial Systems Biomedicine. (Clockwise, from left) Cancer Center Director Michelle Le Beau, PhD, presented the 2011 Shubitz Award to Charles L. Sawyers, MD; More than 750 people attended the annual Merchandise Mart DreamHome preview party to support the UCCRF; Kulhman’s Krusaders Founder John Kuhlman and Master of Ceremonies Tim Smithe helped raise more than $55,000 at a family event in April; Annual “No Tie” Ball Gala Co-Chairs Jeff Feste and Lindsay Essi and Donations Chair Alex Reo oversaw the Associates Board’s annual event which raised $35,000; Swim coaches Mike Cunningham and Laura Thomas encouraged young participants of a swim-a-thon at the Midway Aquatics Club that raised $4,000 for pediatric cancer research; More than 100 people attended a Women’s Board cocktail party at Tiffany & Company in April in honor of Paloma Picasso (right), the daughter of one of the 20th century’s most influential artists; and United-4 A Cure presented Vani J. A. Konda, MD (center), with $15,000 for her research on nanocompounds for the early detection of colon cancer. 25 UCCCC 2010-2011 Annual Report The University of Chicago Cancer Research Foundation The UCCRF is a not-for-profit organization, founded in 1946 by retail store entrepreneur Maurice Goldblatt, following the death of his brother, Nathan, from cancer. The UCCRF plays a key role in helping the UCCCC enhance cancer care, develop more effective and safer therapies, and promote prevention and screening research. Your donation to the Foundation: ++ Supports innovative research to understand cancer’s biomedical complexities UCCRF Board of Trustees Officers Ruth Ann Gillis McGuinnis President Thomas J. Duckworth Vice President Ms. Wende L. Fox Secretary Barton G. Tretheway Treasurer Mary Ellen Connellan Executive Director Members John R. Atchison James N. Bay Jr. Margaret Benjamin Mrs. Seymour A. Cohen Richard W. Cusack John W. Derse Jr. Lidia Devonshire Mrs. Leonard S. Florsheim Jr. Stanford J. Goldblatt Charles P. Hammersmith Jr. Stephanie Harrold Mrs. Michael Klein John A. Kuhlman Jr. Debbie Madlener Bruce Ovitz Lori Ovitz Justin Ullman 26 ++ Enables the purchase of state-of-the-art equipment that will enhance diagnosis and treatment Honorary Trustees Seymour A. Cohen Ronald L. Duitsman Leonard Lavin J. Clifford Moos UCCRF Women’s Board Officers Mrs. David W. Devonshire President Ms. Cynthia Reusché Special Advisor Mrs. Thomas C. D’Aprile First Vice President Mrs. David Nuelle Second Vice President Karen L. Manzari Program Chair Barbara C. Sessions Future Planning Chair & Nominating Chair Jill Gosden Pollock Marketing & Communication Mrs. Charles C. Harrold III Board of Trustees Liaison Mrs. Robert Conrad Annual Appeal Chair Mrs. James Brady Mrs. Benjamin Cox Grand Auction Co-Chairs ++ Expands cancer control and prevention efforts to save lives and diminish the harmful effects of cancer Mrs. John R. Atchison Mrs. J. Michael Crouch DreamHome Preview Party Chairs Mrs. William Adams IV Mrs. Henrik Clausen Becky Davidson Mrs. Thomas Eric Kilcollin Mrs. J. Mikesell Thomas Members-at-large of the Executive Committee Members Mrs. Brayton Bunn Alley Mrs. Alexander Anagnost Mrs. Helena Appleton Allison Bacon Mrs. James N. Bay Margaret Benjamin Mrs. Darcy Robert Bonner Mrs. Joseph M. Brickman Mrs. Harris C. Brumfield Mrs. Michael Busch Mrs. William R. Carney Mrs. J. Rowan Carroll Mrs. Benjamin D. Chereskin Mrs. Gregory Chun Mrs. Peter Clemens Ms. Linda Burns Coleman Ms. Anne H. Cox Mrs. Michael Crane Mrs. Richard W. Cusack Mrs. Andrew Da Miano cancer.uchicago.edu ++ Helps train young scientists who will make discoveries that benefit our generation and future generations Mrs. John Derse Mrs. W. Brinkley Dickerson Jr. Mrs. James F. Dugan Linda Finkel Suzette Flood Ms. Susan Florence Mrs. Fahey Flynn Mrs. David W. Fox Mrs. Edward Gillette Mrs. Thomas T. Hall Mrs. Steven S. Helms Lesli K. Henderson Mrs. William J. Hokin Blaine Kinney Johnson Mrs. Donald A. King Jr. Mrs. Bernard J. Kompare Ms. Josephine Krug-Schulte Mrs. Andrew McGaan Robin Josephs McGarvey Mrs. McKay McKinnon Mrs. Edward J. Miller Ms. Elissa Morgante Yoko Kusama Mosher Mrs. Stuart Oran Ms. Jody Oshita-Bajor Ms. M. Bliss Packer Shelley Johnstone Paschke Mrs. Kirby Pearson Mrs. Heber Pierce Wendy Chronister Rogers Mrs. Frank C. Schell III Mrs. James H. Schink Mrs. Gerald D. Skoning Mrs. David H. Song Nancy P. Stevens Ms. Nancy Voss Mrs. Keith Ward Mrs. William Wardrop Laura Werner Ms. Alice Williams-Verhoeven Sustaining Members Dr. Geraldine Balut Coleman Mrs. Robert Alan Conger Mrs. Jeffrey Diermeier Mrs. Gustav Horschke Mrs. Donald Horwitz Mrs. Robert D. Kimball III Mrs. Robert Kramer Mrs. Donald Levinson Mrs. Michael McGuinnis Ms. Sandra Reese Mrs. Harry J. Smedley Jr. Mrs. John C. Stone Jennifer Kamp Tretheway Honorary Members Mrs. Walter E. Auch Mrs. Wendy Becker-Payton Mrs. Robert R. Bell Mrs. Sharon Brix Mrs. Seymour A. Cohen Mrs. Leonard S. Florsheim Jr. Mrs. Margaret Laun-Knauf Mrs. Arthur E. MacQuilkin Mrs. Charles W. Tallent Mrs. Charles Walgreen III UCCRF Auxiliary Board Officers Laurie Foster President Ann Mohn Treasurer Kathy McCarthy Secretary Jan Gaines Finance Debbie Madlener Foundation Liaison/ Membership Peggy Tieman Midge Wegener Event Chairs Jackie Bossu Reservation Chair Kari Roever Ad Book Tierney Sharif Publicity Nancy Gupta Sustaining Member Liaison Members Celeste Alcock Cindy Alston Elizabeth Brandt Margo Calvetti Frost Annette Hickman Terry Kingdom April Krydynski Julie Sullivan Liz Tunney Williams Sustaining Members Leigh Beith Susan Bondurant Barbara Bridges Maggie Flanagan Margaret Jacoby Becky Kolleng Joan Lancaster Betty Ann Manganaro Linda McCann JoAnn McKibben Nancy Napalo Andrea Montross Mary Helen Panje Jan Peterson Cathy Pratt Mary Helen Ray Ginger Stambaugh Patti Tyska Mary Claire White HONORARY MEMBERS Cheri Allen Barbara Devlin Susan Fraley Darlene Landsittel Carol Lynnes Patsy McCurdy Barbara Schmolze Sharon Ubben Christine Youngberg UCCRF Associates Board Officers Justin Ullman President Erin Callahan Vice President Darcy Bonner Treasurer Members Nicholette Andrews Laurel Buchi-Fotre Tearle Calinog Erin Callahan Laura Cason Kate Cox Camille Cozzini Kate Crouch Jamie Cusack Erica Diermeier Lindsay Essi Jeffrey Feste Chris Gilmore Suzanne Griffin Amiel Harper Sheila Keane Caroline Khadder Laura Klement Lisa Krejcik Julie Lissner Mike Logan Susan Loughran Tom McGrath Janelle Mentz Amanda Pierce Alex Reo Megan Robb Jordan Rovito Melissa Rutten Mike Ryan Taaron Silverstein Adam Simon Krishna Simonetti Jason Sochol Rob Soraparu Scott Stelzer Rachel Strassner Jenna Szkatulski Ashley Szybala Chaidan Upp (From left) Women’s Board President Lidia Devonshire, UCCRF Board of Trustees President Ruth Ann Gillis McGuinnis, Jean Atchison, and Joan Crouch. (From left) Ernst Lengyel, MD, PhD, Auxiliary Board “Spring Forward” Event Co-Chair Midge Wegener, Event Co-Chair Peggy Tieman, UCCCC Director Michelle Le Beau, PhD, Tara Henderson, MD, MPH, Samuel Volchenboum, MD, PhD, MS, and Auxiliary Board President Laurie Foster Baker. 27 Women’s Board President Lidia Devonshire and her husband David examined some of the items available in the silent auction at the annual cancer ball. UCCCC 2010-2011 Annual Report (From left) Liz Adams and Becky Davidson co-chaired the annual cancer ball. 2010-2011 Honor Roll of Donors The UCCCC gratefully acknowledges those who have generously supported cancer research and cancer-related programs and services at The University of Chicago. These donations help the UCCCC explore and develop innovative ways to prevent, diagnose, and treat cancer. The following alumni, friends, foundations, and corporations have demonstrated their extraordinary loyalty and commitment through leadership gifts. These gifts include cash, matching gifts, securities and property, pledges, and pledge payments received July 1, 2010–June 30, 2011. Director’s Leadership Circle $1,000,000+ American Cancer Society, Inc. Cancer Research Foundation Leukemia & Lymphoma Society Virginia & D.K. Ludwig Fund for Cancer Research William F. O’Connor Foundation Diamond Circle $250,000 – $999,999 American Cancer Society Illinois Division, Inc. American Society of Clinical Oncology Anonymous The Breast Cancer Research Foundation The Chicago Community Foundation Crohn’s & Colitis Foundation of America, Inc. Thomas J. Duckworth & Connie Duckworth Mrs. Arthur Edelstein The Entertainment Industry Foundation Dr. Ralph & Marian Falk Medical Trust Foglia Family Foundation/ Mr. & Mrs. Vincent W. Foglia Gabrielle’s Angel Foundation for Cancer Research Goldman Sachs Philanthropy Fund 28 Susan G. Komen Breast Cancer Foundation G. Harold & Leila Mathers Charitable Foundation Bernice* & Earl Meltzer Pfizer, Inc. Searle Funds at The Chicago Community Trust Segal Family Foundation / Carole B. & Gordon I. Segal The Simmons Mesothelioma Foundation The UCCRF Women’s Board Sapphire Circle $100,000 – $249,999 Abbott American Society for Radiation Oncology (ASTRO) Anagen Therapeutics, Inc. Anonymous Avon Foundation Ben May Charitable Trust Blum-Kovler Foundation, Inc. Burroughs Wellcome Fund Cancer & Leukemia Group B Foundation Cancer Research Institute Damon Runyon-Walter Winchell Cancer Fund Elsa U. Pardee Foundation Enivar Charitable Fund Fanconi Anemia Research Fund, Inc The Field Family Flight Attendant Medical Research Institute Focused Ultrasound Surgery Foundation The Francis L. Lederer Foundation Mr. & Mrs. Richard Gonzalez Jeffrey B. & Penny J. Hecktman, Hillary Hecktman, Candace and Daniel Arnold, Valerie Hecktman Hyundai Motor America Mr. Kenneth R. Jensen Kirkland & Ellis Foundation Kovler Family Foundation Leukemia Research Foundation, Inc. Michael Rolfe Pancreatic Cancer Foundation National Marrow Donor Program Project Ladybug Prostate Cancer Foundation St. Baldrick’s Foundation The UCCRF Auxiliary Board The V Foundation for Cancer Research Zaccone Family Foundation Ruby Circle $50,000 – $99,999 Alvin H. Baum Family Fund American Society for Blood & Marrow Transplantation Bears Care Foundation The Brinson Foundation Cantor Fitzgerald Relief Fund Diermeier Family Foundation / Mr. & Mrs. Jeffrey Diermeier cancer.uchicago.edu The Dominick’s Foundation FJC A Foundation of Philanthropic Funds Ronald & Sondra Katz Lung Cancer Research Foundation Marsha Rivkin Center for Ovarian Cancer MPD Foundation Mr. Richard K. Mullin & Ms. Mary J. Henry Neuroblastoma Children’s Cancer Society The Ovarian Cancer Research Fund, Inc. Jeff, Linda & Katie Sluman Mr. & Mrs. Nicholas J. Vogelzang Jr. Platnium Circle $25,000 – $49,999 Anonymous American Heart Association Mr. & Mrs. James N. Bay Jr. Boston Scientific Corporation Mr. William Connelly Mildred & Marv Conney Mr. Jerome Contro Robert & Susan Cook Craig & Janet Duchossois Estate of Joyce M. Perlman Dennis* & Kathleen Ferguson Jim & Karen Frank The Helen & Bernard Kozloff Family Foundation Housewares Charity Foundation Howard Hughes Medical Institute J.B. Pritzker Family Foundation Kazan, McClain, et al Foundation, Inc. Denise Kozloff Mr. E. Bernard McKay Ms. Rita Meltzer Merchandise Mart Properties, Inc. Michael Reese Health Trust Multiple Myeloma Research Consortium National Foundation for Cancer Research Respiratory Health Association of Metropolitan Chicago Mr. Anthony Santacroce Valda & Robert Svendsen Foundation Ms. Marie Wilkinson* Mrs. Harry Woldenberg Gold Circle $10,000 – $24,999 John Amboian, AB’83, MBA’84 & Ann Lee Amboian, AB’83 American Lung Association Mr. & Mrs. Bruce Anderson Anonymous Arlington Million Ladies Barclays Capital Mr. & Mrs. Lawrence Benjamin Biogen, Inc. Mr. & Mrs. James Bozik Ms. Kathleen E. Chapski Mr. & Mrs. Benjamin Chereskin Chicago West Suburban Unico Chicago White Sox Charities, Inc. Mr. & Mrs. Andrew Da Miano Mr. & Mrs. David W. Devonshire Eli Lilly & Company Exelon Corporation Fidelity Charitable Gift Fund Ms. Jean Gelbort Mr.* & Mrs. Robert B. Gelbort John & Charlotte Gilmore Grosvenor Capital Management, L.P. Mr. & Mrs. Charles C. Harrold III Harry F. & Elaine Chaddick Foundation / Mr. & Mrs. Christopher C. Craven Heat & Frost Insulators I-I District Kiwanis International Spastic Paralysis Research 29 The John & Charlotte Gilmore Foundation John Hayes Memorial Golf Outing John W. Anderson Foundation Johnson & Johnson Pharmaceutical R&D Junior Cancer League Kadrovach-Duckworth Family Foundation The Kathleen B. & Charles R. Walgreen III Foundation / Mr. & Mrs. Charles R. Walgreen III Katten Muchin & Zavis Foundation, Inc. K-Five Construction Corporation Klein Tools, Inc. Ms. Josephine M. Krug & Mr. Gerard Schulte Mr. William J. Krug & Ms. Marta Ramirez Krug Andrea & Benjamin Leshem Mr. & Mrs. Michael J. McGuinnis Mr. William J. Meyer John Nuveen & Co. Incorporated Mr. & Mrs. John Paleczny Partnership for Cures Mrs. Cynthia M. Reusché Mr. Harvey Schaffer Mr. Charles G. Schultz UBS AG The UCCRF Associates Board The Windy City Classic Foundation Mr. & Mrs. Justin Ullman Wells Fargo Foundation Silver Circle $5,000 – $9,999 Mr. Grant Achatz Mr. & Mrs. William Adams IV Anonymous (2x) Mr. & Mrs. Patrick J. Baert Mr. & Mrs. Joel Barnett Mr. Neil Berg Berger Company Ms. Cynthia M. Bernardi Mr. Larry Berning Mr. & Mrs. Thomas Brady Brian Delanty Invitational Mr. Zachary B. Bulwa Charles Hammersmith & Carol Hammersmith Family Foundation / Mr. Charles P. Hammersmith Chubb Corporation Cooney & Conway Tricia & Benjamin Cox Mr. & Mrs. J. Michael Crouch Cure It On The Court Ms. Carol K. Dugan The Duk Young Foundation / Mr. & Mrs. Gregory H. Chun Mr. & Mrs. Michael Hannafan Mr. Austin L. Hirsch & Ms. Beth Gomberg-Hirsch Ms. Deanna Hodges Mr. Marvin Jacobs JBS Foundation The Lisa Klitzky Foundation Rally for Kids Marlowe & David Klitzky Mr. Robert A. Lopp Modestus Bauer Foundation Moneris Solutions, Inc. Mr. J. Clifford Moos Mr. Stephen D. Nechtow Paul & Joan Rubschlager Foundation / Paul & Joan Rubschlager Jill Pollock & Gordon Lee Pollock, MBA’73 Mrs. Linda Quasney Mr. Gregory P. Richards Searle Family Trust Douglas* & Loretta Spesia Mr. & Mrs. Robert Swartz Tieri Family Fund Vanguard Charitable Endowment Program Verdura / E. J. Landrigan, Inc. William Blair & Company Dr. James Williams Bronze Circle $2,500 – $4,999 American Society of Hematology Mrs. Alexander Anagnost Anonymous (2x) Mr. & Mrs. John R. Atchinson Mr. Peter Bajor & Ms. Jody Oshita-Bajor Sarah & Blake Berg Ms. Camilla Dietz Bergeron Bolton Sullivan Fund Marta Bonner & Darcy Robert Bonner Mr. & Mrs. Harris Brumfield Mr. & Mrs. John T. Callahan Carleton College Henrik & Annemette Clausen Ms. Rebecca Davidson Deutsche Bank Securities, Inc. UCCCC 2010-2011 Annual Report Dr. Steven Doran Drs. Doran, Capodice, Efaw & Ocheltree Mr. & Mrs. Louis A. Ebert Estate of Lillian Z. Bronkhurst Mr. Marc Feliciano & Mrs. Carolyn Pleyto-Feliciano Paul Fricke, MBA’72 Dr. & Mrs. Damien A. Gabis Mr. & Mrs. Steven S. Helms Frances Henkel & Michael Henkel J.S. Frank Foundation Mr. & Mrs. Jan Jamison Mr. Ron Johnson Sr. Mr. & Mrs. Thomas E. Kilcollin Lance Armstrong Foundation Mrs. Elisabeth F. Lanzl Judy & Wayne Lewis Mr. Laurence Lewis Lilly Mr. & Mrs. Robert Linn Mr. Zdenck Machalka Maurice H. Givens Charitable Trust Mr. Peter A. McLean Jill & Paul Meister Mrs. Edward J. Miller Ms. Tamara L. Mortell Oppenheimer & Co. Mr. & Mrs. Timothy Ozark Mr. & Mrs. Marvin C. Peterson Mr. & Mrs. Stephen Quazzo Robert Okin Foundation, Inc. Mr. James L. Rosenbloom RST Memorial Cancer Foundation Mr. & Mrs. David R. Schwartz Select Equity Group, Inc. Coleman R. Seskind, MD Mr. John Silverman The Stephen Family Mr. & Mrs. Barton G. Tretheway US Trust/B. Of A. Private Wealth Mgmt. Mr. James M. Weichselbaum & Ms. Susan L. Weichselbaum Dr. David H. Whitney & Dr. Juliana Chyu Mr. & Mrs. Samuel Zell Donations Support: Novel proteomics study of neuroblastoma, a disease that affects mostly infants and children. Founders $1,000 – $2,499 Mr. & Mrs. Brayton B. Alley Mr. & Mrs. Richard Almeida Ms. Joanne Brooks Alter * Deceased Donations Support: Sophisticated analysis of highthroughput DNA sequencing results to help develop more individualized cancer therapies. Amanda Dombrowski Scholarship Fund AmeriTrade, Inc. Amgen, Inc. Mr. & Mrs. Robert O. Anderson Mr. Jeffrey P. Aranyos Ms. Joan Aranyos ArcelorMittal Arch W. Shaw Foundation Ms. Diane Patricia Atwood & Mr. Paul J. Reilly Jr. Mr. & Mrs. George Babson Dr. Richard L. Baron Mr. Timothy A. Barrows Ms. Nancy Bellew Renee Belman Ms. Bonnie J. Benson Mr. Steve Berger & Ms. Shereen Taylor-Berger Ellen H. Block Mr. James F. Brady & Mrs. Terese Eckelkamp-Brady Mr. & Mrs. Russell Brandstetter Mr. Steven L. Braun Brooks Family Trust Ms. Ruth E. Bruch Mr. & Mrs. Samuel Buchsbaum Pauline M. Burelli Melissa & John Burnstine Mr. & Mrs. Michael J. Busch Mr. & Mrs. William F. Cahill Carleton Cuts for Cancer Annette Carroll, MBA’85 & John Rowan Carroll, MBA’96 Mr. & Mrs. John F. Chizmar Mr. & Mrs. Peter Clemens Mr. & Mrs. Neil Coleman The Comer Family Foundation Mr. & Mrs. Kevin A. Connellan Mr. & Mrs. Robert L. Conrad Patricia O. Cox Ms. Helen B. Daigle Thomas C. D’Aprile & Nichole D. D’Aprile Mr. William G. Dempsey Marti DeGraaf & Toby Mack Mr. & Mrs. John W. Derse Jr. Mr. Richard Dombrowski Mr. & Mrs. Ronald L. Duitsman Ellen & Ronald Block Family Foundation Dr. Joseph Favia Mr. & Mrs. Fred Feinstein Mr. & Mrs. Paul J. Finnegan 30 Dr. & Mrs. Timothy Flood Mr. & Mrs. David W. Fox Jr. Dr. Gregory Friberg Mr. Thomas L. Fritzlen Jr. Mr. Peter Gaido Garrett Family Foundation Mr. & Mrs. Scott Garrett Mr. & Mrs. James Gelbort GEM Realty Capital, LLC Mr. & Mrs. Edward S. Gillette Mr. & Mrs. Thomas Glettsman The Greater Kansas City Community Foundation Dr. & Mrs. Raj P. Gupta Mr. David P. Hartney Winifred & Kirt Hayes HEB Foundation Ms. Katie Hicks Mr. & Mrs. Laurence Dean Hill Mr. & Mrs. Howard Hoffmann Mr. & Mrs. Timothy Hurd Illinois Prairie Community Foundation Mr. Kenneth M. Jacobson James R. & Lesley B. Anixter Family Foundation / Mr. & Mrs. James Anixter Jamison, Inc. Mr. Steven D. Jensen Jewish Federation of Metropolitan Chicago John & Jacolyn Bucksbaum Family Foundation / John & Jackie Bucksbaum Mr. & Mrs. Rob Johnson Mr. & Mrs. Roger B. Johnston Jordan Industries Incorporated Ms. Carol W. Keenan Mrs. Gwen Klein Paul Knapp, MBA’77 & Nancy Knapp Mr. Neal Kottke Mr. John A. Kuhlman Jr. Mr. & Mrs. Gilbert W. Kurschner Jr. Julius Lewis Mr. John P. Lynch Mr. & Mrs. Craig W. Mann Mr. & Mrs. George Mann Karen Manzari & Tony Manzari Mr. & Mrs. James F. Martin Ms. Nina B. Matis Ms. Noreen McGuire Dr. & Mrs. McKay McKinnon Merrill Lynch & Co. Foundation, Inc. Mr. & Mrs. Stephen Meskan Mr. & Mrs. Robert Johns Mignin Mr. & Mrs. Brian P. Miller John P. & Carol E. Mordach Morgante Wilson Architects, LTD. / Mr. Fred Wilson & Ms. Elissa Morgante Mr. & Mrs. Robert S. Morrison Evelyn Mueller Ms. Harriet Nathan Neal, Murdock & Leroy, LLC Mr. Langdon D. Neal & Ms. Jeanette Sublett Mr. Nick Niciforo Northwestern Mutual Foundation Mr. & Mrs. David Nuelle Bruce & Lori Ovitz Packard Research Foundation Ms. Mary Bliss Packer Kathleen Palla Mr. Nicholas D. Pannacciulli Mr. & Mrs. Brett Paschke Debra & Robert Peterson Mr. & Mrs. Heber Pierce Colette O. Pollock Kenneth Samuel Polonsky, MD & Ms. Lydia Ray Polonsky PolyScience Mr. Thomas H. Quinn Rally For Kids With Cancer Foundation Mr. & Mrs. Lucius E. Reese The Rhoades Foundation Mr. & Mrs. David Richter Mr. & Mrs. Michael Gerard Rippey Mr. & Mrs. Randall S. Rogers Mr. John C. Rosengren Mrs. Elinor Salvino Mr. Scott Sauer Ms. Nicole C. Schachner Mr. & Mrs. Frank Charles Schell III Mr. & Mrs. Richard J. Schiene Mr. & Mrs. James Schink Ms. Martha E. Schmidt Mr.* & Mrs. Richard Scully Mr. & Mrs. Rob Selati Mr. & Mrs. Rex Sessions Mr. Arch Shaw II Ilene Warshawsky Shaw, AM’75 Ms. Jean E. Sheridan Mr. & Mrs. Frank M. Sims Mr. & Mrs. Gerald D. Skoning cancer.uchicago.edu Donna Speigel Ms. Geraldine Stein Ms. Bonnie J. Struthers Mr. & Mrs. Timothy P. Sullivan Supera Family Foundation Mr. & Mrs. John Svoboda Mr. & Mrs. Mikesell Thomas Ms. Mary L. Tieri Dr. Everett E. & Dr. Tamara Vokes Ms. Nancy Voss Mr. & Mrs. Franklin Wallace Mr. & Mrs. Keith Ward Mr. & Mrs. William S. Wardrop Jr. Mr. James Watson Jr. Mr. Roy Weaver Mr. & Mrs. Michael Werner Ms. Lynn M. Wesley Ms. Alice WilliamsVerhoeven & Mr. Gary Verhoeven Winston & Strawn Ann S. Wolff Mr. Dominic Zaccone Dr. & Mrs. Lawrence Zachary Benefactors Under $1,000 A. Smaltz Inc./DBA The Ground Crew Mr. Joel Aarons Darrow Abrahams Ms. Ellie Abrams Ms. Lucille Ackerman Ms. Lucille N. Ackerman Mr. Hall Adams III Barbara Stolberg Adelman, AB’70, MBA’76 & Steven Adelman Ms. Donna Adelsperger Ms. Yolanda Torrisi Adler Agape Foundation Ms. Naza Agassi Mr. Peter Akemann Ms. Kate Alcantara Mr. & Mrs. Dino Alex Mr. Constantine Alexander Ms. Nell Alexander Ms. Shirley C. Alexander Allard Rental Corporation Mr. & Mrs. Chad M. Allen Ms. Marianne E. Allen Mr. & Mrs. Gary A. Allen Mr. Ronald J. Allen Mr. & Mrs. Stephen E. Allen Mr. Leo F. Alt Alternative Reproductive Resources Ms. Martha Altmin Ms. Hope Alvarado Mr. John Amato Amgen Foundation Inc. Mr. William Amonda Mrs. Helen Andersen Ms. Dawn M. Anderson Ms. Georgean L. Anderson Mrs. Helen R. Anderson Ms. Janice Anderson Mr. Douglas Andrews Ms. Nicholette Andrews Mr. George Andronikidis Mr. & Mrs. Pete Angelos Mr. Michael Anguiano Anonymous (3x) Mr. John R. Appleton Dr. Maureen K. Archambault Ms. Darlene L. Ardelean Mr. William Argall Dr. Eva S. Arkin Mr. & Mrs. Edward G. Arman Ms. Joy Arnold Mr. & Mrs. Bruce Arquilla Mr. James Austin Mr. & Mrs. Myron D. Austin Auto Parts City, Inc. Azemi’s Management, LLC Ms. Lesli Babbs Mr. Robert F. Bacigalupo J. Douglas Bacon & Allison Bacon Mr. John Badeusz Mr. & Mrs. Thomas E. Baier Dr. & Mrs. Kent N. Bailey Bailey-Love Mortuary Baker Tilly Virchow Krause, LLP Mr. Bradley Bakle Ms. Mary N. Baldwin Ball State University Ball State University – Department of Journalism Ball State University – Dean, Teachers College Mr. Marshall J. Ball* & Mrs. Paula Ball Mr. & Mrs. Eugene F. Bandy Bank of America Foundation Barack Ferrazzano Kirschbaum & Nagelberg Mr. & Mrs. Christopher Barber Mrs. Jane Barbera Ms. Megan Barcheski Barker & Castro LLC Mr. Lee Charles Barker Ms. Elizabeth M. Barnett Mr. John R. Barney Ms. Nancy Barrett 31 Ms. Sheila Marguerite Barrett Barry C. Kessler & Associates Ms. Robbie Barscz Ms. Vida Bartkus-Murray Mr. & Mrs. David V. Basile Mr. & Mrs. Shale D. Baskin Robert Batlivala Ms. Mary F. Baudino Ms. Marcia Baugh Mr. & Mrs. Bernard M. Baum Mr. & Mrs. Richard W. Baum Mr. Oscar E. Rebollo & Ms. Suzanne Baum Ms. Vittoria Baum Mr. Christopher J. Baumbach Ms. Margaret Baumgartner Baxter Employees Giving Campaign Baxter International Foundation Bear Cartage & Intermodal, Inc. Mr. William Bebonis Ms. Maryellen Begley Ms. Michelle Beierle Mr. J. Edward Bell Ms. Nicole Bell Mr. Ricky J. Bender Mr. Richard M. Bendix Ms. Joanne J. Benedick William J. Bennett III, DDS Ms. Jeanne B. Bercovitz Mr. & Mrs. James P. Bereolos Mr.* & Mrs. Louis A. Berger Mr. Blake M. Berish Mr. & Mrs. Alan G. Berkshire Mrs. Linda Berkson Mr. & Mrs. Arthur L. Berman Mr. Arthur M. Berman Mr. & Mrs. Mark Bernstein Mr. Scott A. Berry Mr. & Mrs. Phillip L. Best Ms. Constance Beucus Ms. Judith A. Beyer Marjorie Biederman Mrs. Andrea Biel-Cohen Friends of the Biological Sciences Ms. Joanne Linda Biondi Mr. Lewis Bird Bishop Plumbing, Inc. Ms. Sharon M. Bishop Mr. & Mrs. C. Edward Bjorncrantz Mrs. Raye Black Ms. Tambra Black Ms. Gail Blackmun Mr. Gilbert Blackmun* Ms. Julie Blackmun Mr. Ronald Blaine Ms. Ruth Blatt Lexis S. Blitstein Mr. Neil Blitstein Ms. Mary Lou Block Ms. Francine Bloom Board of Education District 27 Mr. Matthew C. Boba Chris & Natalie Boden Michele L. Bograd, PhD Mr. & Mrs. Gary R. Bohl Mr. Julius Bokodi Ms. Leah Bolger Mrs. Lillian F. Bolkovatz Mr. & Mrs. David Bolson Mr. & Mrs. Scott Bondurant Mr. Gary Bonk Mr. Stephen Bonnema Mr. & Mrs. Dennis S. Bookshester Mr. & Mrs. Daniel J. Boote Ms. Eva Bordeaux Mr. & Mrs. Ronald J. Borden Ms. Suzanne Boren Mr. & Mrs. Erwin R. Borowsky Gerard A. Boston, DVM Ms. Joyce E. Both Ms. Laurice Boulos Ms. Lynne E. Bouzeos Ms. Susan A. Bovbjerg Mr. Ed Bovich Mr. Jeremiah Bowman Mr. Terry A. Bowman Mr. & Mrs. John T. Boyle Mr. Bruce C. Boynick & Ms. Andrea A. Moonsammy Mr. John A. Bracha Ms. Adelaide B. Brady Mr. Brooke Brady Mr. & Mrs. Curtis Brandon Mr. Hubert Brandt Mr. & Mrs. John A. Brandt Mr. & Mrs. John Brane Ms. Maryellen B. Brault Ms. Flora Braziel Ms. Kathryn G. Brenner Mr. Jason Brezler Mr. & Mrs. Joseph M. Brickman Mr. & Mrs. Thomas A. Briden Ms. Deborah Briehan Mr. Richard A. Broeren Brotherhood of Asea,Inc. Mr. & Mrs. Raymond Brower Ms. Jennifer Brower UCCCC 2010-2011 Annual Report Mr. Charles M. Brown Ms. Fern G. Brown Mr. & Mrs. Frederick J. Brown Ms. Jennifer Brown Mr. & Mrs. Michael J. Brown Ms. Rebecca A. Bruckner David Brueggen, MBA’75 Mr. Daniel P. Bruggeman Mr. & Mrs. Jack F. Bryant Mr. & Mrs. John C. Bucher Mr. & Mrs. John A. Buck, III Ms. Marguerite R. Buckingham Mr. Paul A. Buckley Ms. Laura Budd Ms. Paula R. Buddy Mrs. Alice B. Burgess Mr. & Mrs. Craig Burgess Mr. & Mrs. Gregg Burgess Ms. Vicki L. Burgess Raphael A. Burnstein, PhD Mr. & Mrs. James Bushnell Ms. Heather Bushong Mr. Bryan Bussan Mr. & Mrs. William J. Butrym Mr. J. Denson Buttrey Mr. Steven Buzzard Mr. Bryan Bylica Mr. David D. Byrne Mr. & Mrs. Patrick T. Byrne Ms. Carol J. Byrnes Ms. Lynn Byrnes Ms. Barbara A. Byron Mr. David S. Byron Ms. Angelinn M. Caffarini Mr. Michael J. Calandro Mr. & Mrs. G.J. Caldwell Mr. & Mrs. Martin T. Callaghan Ms. Deborah Callahan Ms. Erin Callahan Callaway Golf Company Foundation Ms. Corina M. Cardamone Mr. & Mrs. John A. Carlson Carnegie-Mellon University Ms. Emanuela Z. Carney & Mr. William R. Carney Ms. Mary A. Carney Carolyn AlbertKincl Design Mr. Philip Carrier Mr. & Mrs. Duane Cart Ms. Susan Joanne Carton Mr. & Mrs. Douglas Carucci Mr. & Mrs. Timothy J. Cavanagh Celebrated Chefs Mr. & Mrs. Denis Cerezo Ms. Jeannene Chadruc Donations Support: Reconstructive microsurgery for the treatment of breast cancer. * Deceased Donations Support: Immunotherapy for the treatment of melanoma, one of the deadliest cancers. Ms. Z. Kathy Chamah-Cameron Chaney-Monge School District #88 Chaney-Monge Teacher’s Organization Ms. Betty Charles Ms. Ching-Fen Chen Chicagoland & Italian American Charitable Organization Ms. Laura M. Chihara Ms. Linda C. Chizmar Ms. Rose Chodzinski Mr. & Mrs. Burton Chotiner Ms. Sandy Christafferson Mrs. Wendy Chronister Mr. & Mrs. Donald Chudacoff City Publication North Shore Chicago Ms. Nancy J. Claar Mr. & Mrs. Peter Claeys Ms. Marjorie Bomberger Clark Mr. Stevie Clark Mr. & Mrs. Charles F. Clarke III Classic Touch Painting, Inc. Mr. & Mrs. Kenneth L. Clement Ms. Laura Clements Ms. Toni Clementz Ms. Emilie Cloutman Mr. & Mrs. Thomas R. Cloutman Mr. Zack Cloutman CM&P Consultants, LLC Ms. Lauren Coburn Mr. Jeff Coburn & Ms. Pamela Hanratty Mr. & Mrs. Richard L. Cohan Mrs. Barbara P. Cohen Dr. Ezra Cohen Ms. Jill Cohen Ms. Rosanne Cohen Mr. Stuart Cohen Mr. & Mrs. Barry Cohn Mrs. Elaine Stone Colburn Dr. Geraldine Balut Coleman College of St. Benedict Mr. & Mrs. Michael F. Collins Mr. & Mrs. Ronald A. Colosimo Mr. Byron B. Colvis Community Shares of Minnesota Ms. Carrie Compobasso Ms. Heather Concklin Richard S. Conen, DDS & Mrs. Beth Miller Conen Connors Industrials, Inc. 32 Mr. Robert E. Connors Ms. Merle R. Cooper Mr. & Mrs. Arthur Coren Alene Corken Mr. & Mrs. Dean P. Coronato Ms. Cara Cosentino Country Curtains Mail Order Inc. County Municipal Employees Supervisors & Foremens Union 1001 Mr. Matthew Cowen Ms. Karen A. Cowperthaite Ms. Catherine Cox Ms. Josephine A. Cox Mr. & Mrs. David J. Cox Ms. Rebecca Cox Mr. Fred Crandall Mr. & Mrs. Michael E. Crane Mr. Bruce Cravens Mr. Matthew Cross Keith Crow, JD’86 & Elizabeth Parker, AM’87 Mr. & Mrs. Merwin R. Crow Mrs. T. M. Crowley Ms. Carol J. Culberson & Mr. James Fehling Jaime Cumberworth-Sisti Ms. Dorothy L. Cummens Ms. Alexandra Rose Cunliffe Ms. Kathleen Curran Barbara Flynn Currie, LAB’58, AB’68, AM’73 Mr. James Cusack Mr. & Mrs. John A. Cutler Mr. Robert Cutler Mr. & Mrs. Le Roy T. Czarnecki Ms. Doris Czarobski Ms. Denise Czuprynski Ms. Katherine Dagres Mr. & Mrs. Eric Dahl Mr. & Mrs. Robert Daldegan Dare To Share Ms. Rachel Silverman Darlow Mr. & Mrs. Alex Daudsyah David Apple Ltd. Mr. & Mrs. Ellsworth G. Davis Mrs. Laura Sims Davis Mr. & Mrs. Harry W. Davis Ms. Elizabeth Day Mr. Hybo L. De Blecourt Ms. Jillayne E. Deakins Mr. Santolo M. Deblasio Mr. Steven Deer Mr. Dean D. Degan Ms. Joan E. Dehnert Mr. Ardell Deiber Mr. & Mrs. Philip Deiotte Mr. Akinwande Delano Ms. Angela L. Delgado Mr. & Mrs. Steven Deli Denemark Periodontal Specialists, LTD Mr. & Mrs. Paul Denemark Ms. Denise Dentley Mr. Grant DePorter Mr. & Mrs. Tony DeSalvo Design Window Solutions, Inc. Ms. Rita Dessner Mr. Ronald DeTella John R. DeVries, DVM Mr. & Mrs. Anthony M. Di Lorenzo Mr. Gerald Diamond Mr. Carlos Dias Dick Van Dyke Financial, LTD. Ms. Lillian L. Dick Mr. Raymond Dickinson Dickson & Hasenbalg Mr. Jeffrey J. Diehl Mr. Robert F. Dieli Mr. Vassilios Dimitriadis Discover Financial Services Ms. Elizabeth Diver Mr. & Mrs. Dan Dixon Mr. Peter Dixon Mr. & Mrs. David Dobbs Mr. William Robert Dodds Jr. Ms. Karyn Louise Doerfler Mr. Duane A. Doerle Mr. John A. Doerrer Ms. Marie E. Doleman Ms. Marlene Domash Ms. Priscilla W. Dombek Ms. Grace M. Donaghey Mr. Phillip B. Donenberg Ms. Joy Ann Donewald Ms. Kathleen Donohue Mrs. Virginia K. Donohue Mrs. Nancy S. Donovan Dr. Amir Dorafshar Mr. Michael Doran Dr. & Mrs. Heratch O. Doumanian Dowd Wescott Group, LLC Ms. Mary Vita Drennan Mr. & Mrs. Angelos Dres Mr. & Mrs. Ross Drobny Mr. & Mrs. Michael Dry Ms. Margaret R. Du Bernard Ms. Loretta Dubovik Ms. Helene Dubow Mr. & Mrs. William J. Ducey Ms. Claire Ducey-Bach cancer.uchicago.edu Mr. George E. Duchossois Mr. & Mrs. Richard F. Duffy Nancy Dugan, MBA’97 & James Dugan The Duncan Family Mr. & Mrs.* E.R. Dunn Mr. & Mrs. Ray A. Dybala Mr. & Mrs. Gerald T. Eager East-West Home Title, Inc. Mr. Daniel A. Edelman Ms. Julia Edelmann Mr. Ryan Edlefsen Ms. Judith Edwards Ms. Carolyn C. Eggers Ms. Lynn Eikenbary Mr. & Mrs. Patrick Eilers Ms. Mary A. Ekovich Mrs. Victoria Eley Mr. Dale J. Elkins Mr. Michael J. Elkins Dr. Leonard D. Elkun Mr. & Mrs. Peter Elliott Mrs. Margaret S. Elliott Ms. A.J. Ellis Ms. Laurie J. Elm Ms. Gloria D. Elmore Ms. Phyllis Elsbury Mr. John W. Empfield & Mrs. Mary Donohue Empfield Mr. & Mrs. Donald L. English Mr. & Mrs. Scott M. Engstrom Mr. & Mrs. Thomas J. Enrici Mr. John J. Enright Ms. Charlene Entman Mr. & Mrs. Jerry W. Epton Mr. & Mrs. Daniel K. Ericson Mr. & Mrs. Sam D. Esposito Mr. & Mrs. Mark Essi Ms. Lindsay Essi Mr. Allan Etzbach Ms. Elizabeth Eugenio Ms. Katherine K. Evans Mrs. Louise M. Evans Ms. Margaret M. Evans Mr. & Mrs. Ronald L. Evans Mr. Reese L. Evans Mr. & Mrs. Shane Exner Mr. & Mrs. Bryan A. Fabry Facing the Mirror with Cancer, LLC Faermark & Williams LLC Ms. Mary Jo Fasan Mrs. Evelyn K. Faulstich Ms. Gayle L. Fazzini Mr. Scott B. Feder The Federal Metal Company Mr. & Mrs. Mitchell Feldman Mrs. Terri R. Feldman Mrs. Alice E. Felton Mr. & Mrs. John A. Ferguson Mr. Daniel Ferri Mr. Jeffrey Feste Krage Feste Ms. Carole L. Fiducci Barbara Field & Lawrence Field Mr. & Mrs. Theophilos G. Fifles Mr. & Mrs. Robert Finkel Ms. Elaine Finnegan Mrs. Lauren Fischer Mrs. Cheryl Fisher Mr. & Mrs. Don Fisher Jr. Ms. Mary Fisher Mr. Russell Fishman Dr. & Mrs. Frank W. Fitch Ms. Jan Fitzgerald Mr. Stephen W. Fitzpatrick Mr. & Mrs. Richard S. Fleisher Ms. Kathie Florsheim Jill Folan Ms. Maureen Foran-Mocete Ms. Margaret Fosmoe Mr. L. James Lawson III & Mrs. Wende L. Fox Dr. & Mrs. Harry A. Fozzard Ms. Sonia Franco Mieczyslawa Franczyk Ms. Christine C. Franklin Mr. & Mrs. Philip G. Franklin Mr. & Mrs. Jay Franks Frederick & Greta Smiley Charitable Foundation Inc. Mr. Grum N. Frederick Ms. Lynn Fredrickson Ms. Paula Fredrickson Ms. Margaret Fredson Ms. Judy A. Freeze Mr. Louis E. Freidheim Jr. Dr. & Mrs. Robert Alan Freilich Mr. Frank French Mr. & Mrs. Thomas C. Freyman Ms. Harriet Friedly Friends of Cancer Research Friends of the Hospital Friends of the University Mr. Alexander P. Frigo Friman & Stein, Inc. Roger & Madelon Fross Mr. & Mrs. Don E. Fuller Mr. & Mrs. Donald M. Fyfe Ms. Dorothy H. Gaertner Mr. & Mrs. William Gaffin 33 Ms. Karen H. Gaines Mr. John Galambos Mr. Charles J. Gallagher Ms. Marion L. Gallagher Mr. Patrick Gallagher Mr. Salvador Garcia Mr. & Mrs. Glenn Garfinkel Mr. & Mrs. Ron Garfinkle Ms. Martha L. Garrett Ms. Catherine L. Garvey Mrs. Patricia C. Garvy Mr. & Mrs. Ben Gatch Jr. Mr. & Mrs. Joseph J. Gauthier Ms. Florence M. Gavin Mr. & Mrs. Michael J. Gaylor Mrs. Martha F. Gearhart Ms. Patricia Gebler Mr. William Gee Mr. & Mrs. Larry G. Geer Sell Gehring Remodeling Company Mr. & Mrs. Gary Geiger Mrs. Judy Geleerd-Kitzes Ms. Rachel Genduso Gentle Dental Care, P.C. Mr. & Mrs. William C. Gentry Geocaris Law Firm Georgetown University Ms. Susan Geraghty Mr. & Mrs. Frederick J. Geyer Mr. & Mrs. David M. Gibbons Mr. Brian P. Giesche Mr. & Mrs. Laurence M. Gill Mr. R. Scott Gill Ms. Kathleen Gilmore Eric Ginsburg Ms. Rochelle Ginsburg Mr. Robert F. Girgis Ms. Ruth G. Glassenberg Ms. Margaret Glesche Mr. & Mrs. Michael Glickman Ms. Teresa B. Glotzbach Mr. & Mrs. E. Richard Goddard Ms. Erika Goeckner Mr. Langer Gokey Mr. Steve J. Erd & Ms. Stacey Gold Erd Mrs. Jill Scheffler Goldhamer Mr. Dennis K. Goldman Mr. Anthony Golobitsh Mrs. Carol Gonsky Mr. James B. Goodman Mr. & Mrs. Joe Goodwin Ms. Tara L. Goodwin Mr. Edward T. Gordon Gorter Family Foundation Mr. & Mrs. Howard Gossage Mr. Norman Gotteiner Caryl Gout Mr. William A. Grabow Mr. & Mrs. T. Randall Graeb Ms. Lisa Granbur Ms. Judy A. Grant Mr. & Mrs. Gerry Gravina Steven & Chandra Gray Ms. Lisa Greenberg Mr. & Mrs. Gerson Greenburg Mr. & Mrs. Ronald Greenspon Ms. Lydia Gregoret Mr. Jeff Grimes Mr. & Mrs. Jeff Gromos Ms. Wendy S. Gross Ms. Carrie Groszek Mr. & Mrs. Dennis Grover Mrs. Mary Lewis D. Grow Mr. Roy Grow Ms. Jeanne M. Gruhlke Mr. Gilbert R. Guajardo Mr. & Mrs. Hem C. Gupta Mr. & Mrs. David J. Gurin Mr. William Guswiler Ms. Jean Haas Ms. Susan Hagaman Mr. & Mrs. Guy E. Hagen Ms. Marilyn L. Hagler Mr. Bruce Hague Mr. & Mrs. Brian Hahn Hair Watchers Boutique Plus Ms. Bernice L. Hajduk Melina Hale Mr. Joel D. Halper Mr. Jan Douglas Halverson Mr. Michael D. Halverson Ms. Sharon R. Hamilton Reverend & Mrs. Robert C. Hamm Dr. & Mrs. Raymond M. Handler Dr. & Mrs. Jonathan A. Handler Ms. Judith F. Hanrahan Ms. Carol J. Hansen Ms. Peggy Rose Hanson Mr. James Hantak Mr. Kent G. Harbison Mr. Russell M. Harden Mr. Karl R. Hardiman Ms. Beaty R. Harris Mrs. Gwen Harris Mr. Morton J. Harris Mrs. Sheldon Harris Ms. Sara A. Hart Mr. Jeff Harting UCCCC 2010-2011 Annual Report Ms. Margaret Hartney Mr. & Mrs. Michael J. Harvey Jeff Harvey & Julie Shelton Mr. & Mrs. Stephen J. Hauer Mr. Lionel Hawkins III Mr. & Mrs. Brian P. Hayes Ms. Judith B. Hayman Mr. & Mrs. James T. Hayner Ms. Mary M. Healy Mr. & Mrs. Charles G. Hearn Mr. Jeff Heddles Mr. & Mrs. F.F. Hedrick Jr. Mr. James Heffernan JoAnne Heffernan Mr. Christopher K. Hehmeyer Mrs. Martha Heisel Dr. & Mrs. Javad Hekmatpanah Mr. Eric Helfand Mr. & Mrs. David B. Heller Ms. Anne Hellmer Mr. Michael J. Czarnecki Ms. Lesli K. Henderson & Mr. Steven Robert Goldman Mr. & Mrs. Jack A. Henderson Mr. & Mrs. Dylan A. Hengstler Mr. Richard C. Hennessy Herbst Financial Advisors, Inc. Ms. Pamela Hernandez Ms. Lorraine Herr Mr. & Mrs. Chad Herring Mr. & Mrs. Jerry Hersh Mr. & Mrs. Robert Hess Ms. Beverly J. Heydinger Mr. Charles M. Hicks Ms. Katherine Hidaka Mr. & Mrs. Elzie Higginbottom The Highland Park High School Athletic Department Mr. Steven A. Hild Mr. & Mrs. Brian G. Hinds Mr. James J. Hipp Ms. Lindy Hirschsohn Ms. Brooke Hittler Mr. & Mrs. William Hoefs Mr. William V. Hogan Mr. & Mrs. Donald G. Holland Mr. Kurtis Holle Ms. Frances M. Hollister Ms. Lorraine Hollister Mr. Mark E. Holstius Mr. Sheldon P. Holzman Homewood Flossmoor Soccer Club Donations Support: Research into the relationship between hormone signaling and cancer stem cell genes that will lead to new strategies to prevent, detect, and treat prostate cancer. * Deceased Donations Support: Resource Center for storage and dissemination of research-quality tissue for the complex genetic analyses necessary to develop innovative, personalized cancer therapies. Mr. & Mrs. William L. Hood Mrs. Susan R. Hoogland Ms. Barbara R. Hooper Mr. David B. Hooper Hoosier State Press Association, Inc. Ms. Sandra Horberg Mr. Peter Horemiotes Mr. & Mrs. Mark Hornok Mr. & Mrs. William E. Horowitz Mrs. Walter G. Horschke Mr. Jeffrey M. Hortsch Hospira Employee Giving Campaign Hour of Power Ms. Carol H. Houston Mr. James R. Burket & Mrs. Kathleen Howe-Burket Mr. & Mrs. Richard Howenstine Mr. John Dun-Lu Huang Mr. Jonathan Huff Ms. Christy Hughes Mr. Michael Hughes Ms. Lois Hummel William B. & Melanie S. Hummer Li Fang Hung Hunter Douglas Metals, Inc. Mr. Stanley Hurd Arti Hurria Ms. Joseph Hynek Lynette M. Iannantuoni & John E. Iannantuoni, SB’63 IBM Corporation ICMEA Ms. Jacqueline H. Ieuter The Jaffee Foundation The Illinois Organization of Mothers of Twins Club, Inc. Mrs. Vera L. Imhoff Mr. & Mrs. Mario Imparo Mr. & Mrs. Donald K. Inderlied Industrial Services of America, Inc. Mr. Robert A. Ingram INT Interglobal Design Inc. International Brotherhood of Electrical Workers Mr. Sultan S. Issa ITW Foundation Mr. Salvatore Iuliano J & J Newell Concrete Contractors, Inc. J. P. Morgan Chase Foundation Ms. Lynn A. Jachec Mr. Zach Jacobs Ms. Claudia Jacobson 34 Ms. Irit Jacobson Mr. John E. Jacobson Mr. & Mrs. Perry Jager Mr. & Mrs. Rich Jakubowski James & Hoffman Mr. Edgar J. James Ms. Elizabeth Janairo Mr. & Mrs. Keith R. Jans Mr. & Mrs. James R. Janssen Mr. Dean Jarog Sidney F. Jarrow Jean Haas, Inc. Ms. Katherine Jenal Ms. Mary Jenal Ms. Nancy Jenal Mr. Robert Jenal Mr. Steven Jenal Mrs. Linda L. Jennings Ms. Hilary Jensen Joel Kennedy Constructing Corporation Mr. & Mrs. Joseph Johnson Mr. & Mrs. Bruce Johnson Ms. Mary Johnson Mr. & Mrs. Michael Johnston Mr. Norman M. Johnson Ms. Vivian L. Johnson Mr. & Mrs. Jonathan G. Jollief Ms. Dolores Jones Mr. & Mrs. Richard E. Jones Mrs. Pam Jones Ms. Sandra Jones Mrs. Adele K. Joseph JRP Properties LLC Mr. Alan R. Juraska Ms. Marija Jurcevic Mr. & Mrs. Daniel Jurovich Ms. Lois Just Mr. & Mrs. Clark Justice Mr. & Mrs. Lawrence I. Kahn Mrs. James Kahnweiler Ms. Irene Kaim Mr. George M. Kaiser Mr. Hunter Kaiser Mr. Nick Kakos Mr. Donald J. Kallin Ms. Sandra Kamin Ms. Marci Kaminsky Ms. Kristi Kangas Mr. Scott Allen Kappmeyer Mr. & Mrs. Joseph Karacic Mr. & Mrs. Jim Karalekas Karl Knauz Motors Mr. & Mrs. William D. Kasdorf The Kamin Foundation Mr. David Kass Ms. Angela Katinas Mr. & Mrs. Paul Katsabanis Mr. Larry B. Katzbeck Mr. David Kaufman Mr. & Mrs. William Kaufman Mr. & Mrs. Robert W. Kaufman Ms. Marcia A. Kay Mr. Richard Kaylor Ms. Sheila Keane Mr. Joseph S. Kearney Jr. Ms. Ann Keating Ms. Bonnie Keeler Mr. Patrick J. Keenan Jr. Kathryn Keenan Mr. Patrick Keenan Mr. & Mrs. Art Keister Mr. Kevin Keleghan Mr. & Mrs. Dan Kelleher Ms. Natalie M. Keller Mr. Daniel J. Kelley Mr. Donald J. Kelliher Ms. Mary T. Kelly Hanson Ms. Lara G. Kelly Ms. Jennifer L. Kennelly Ms. Annette Kenney Ms. Margaret Kenny Mr. Andy Kenoe Mr. & Mrs. Richard Kerner Ms. Helen Kerrigan Ms. Caroline Khadder Mrs. Jodi Ann Khan Ms. Mary Kiener Ms. Patricia J. Kilcullen Kipnis Rosen & Bloom Ltd Mr. & Mrs. W. J. Klawitter Mr. Fred Klein Ms. Laura Klement Mrs. Catherine V. Knapp Ms. Susan Knight & Mr. Lawrence H. Jones Mr. Fred Lamar Kniss Ms. Megan Knott Mr. Thomas Knott Mr. Michael S. Jacobs & Mrs. Kirbie J. Knutson Ms. Suzanne K. Knutson Mr. Eric Kobe Mr. Eric Kodish Ms. Isabel M. Kodron Mr. & Mrs. Joseph E. Kolar Mr. Michael Kolleng Mr. Douglas C. Kolsrud Mr. & Mrs. David Komiss Mr. & Mrs. Bernard Kompare Mr. & Mrs. George Kontogiannis Mr. Thomas J. Koplos* Ms. Burdette Koran Ms. Pauline A. Kosmitis Mr. Michael J. Kowalewski cancer.uchicago.edu Ms. Marla L. Kowalski Mr. Edward Koznarek Mr. & Mrs. Demetrios L. Kozonis Kramer Enterprises Ms. Kelly G. Krantz Mr. & Mrs. Roderic Krapf Ms. Martie Krassek Mr. Jeffrey Krause Cory Krebsbach Ms. Peggy Kreisman Ms. Debra H. Kretzmann Ms. Stella Kriaras Ms. Esther Krick-Woodward Ms. Rosemary Kriener Ms. Karen C. Kristofik Ms. Barbara Kriyger Mr. & Mrs. Larry Krueger Mr. & Mrs. Robert G. Krug Mr. & Mrs. Mark Krumtinger Mr. & Mrs. Kenneth Krupinski Ms. April M. Krydynski Ms. Joy H. Kuchler Ms. Linda Kuczka Mr. & Mrs. Steven J. Kuehl Mr. John A. Kuhlman Ms. Azra Kulasa Ms. Maureen Kunze Mr. & Mrs. Bud Kuppenheimer Ms. Judith Klemke Kurzeja Ms. Agnes Yao Kwan Ms. Laurian E. Kyritz Mr. James Lagerhausen Ms. Mari Meyer Lagone Mr. & Mrs. Hristos A. Lalopoulos Ms. Edward Lam Ms. Jane B. Lambesis Ms. Shirley Land Mr. Arthur P. Langendorff Mr. & Mrs. Alan Langerud Ms. Penfield S. Lanphier Mr. Alvin Lapper Mr. & Mrs. Richard C. Larsen Mr. & Mrs. Richard D. Larson Mr. Arthur Laschober Ms. Nancy Laser LaSota Investments, Inc. Mr. John LaSota Mr. & Mrs. James O. Latturner Mr. Michael J. Lauesen Law Offices of Daniel J.Kelley Ms. Cherilyn K. Lawrence Mr. Richard E. Lawrence Ms. Linda L. Lawson Dr. Richard B. Lazar & Ms. Jessica E. Tampas Mr. & Mrs. Larry L. Leadley Mrs. Mary E. Lebbin Dr. Michelle M. Le Beau & Dr. Robert Harwood Dr. & Mrs. Kwang-Sun Lee Ms. Sarah Lee Ms. Dawn Lehmann Ms. Julie M. Leider Lemont Family Dental, LTD Ms. Kristina Leng Mr. Matthew B. Lerner Mr. & Mrs. Tom Les Ms. Pamela Lesinski Mr. John Lessick Mike & Susan Levine Dr. Robert L. Levy Ms. Jacqueline James Lewis Mrs. Janet G. Lewis Mr. & Mrs. Steven H. Lewis Mr. & Mrs. Jon J. Lewis Ms. Denise Leyland Ms. Hazel L. Liebling Mr. Curtis W. Lieneck Ms. Marjorie Lieneck Dr. Stacy Tessler Lindau & Dr. Peter Lindau Mr. & Mrs. Carl J. Lindeberg Ms. Morgan Lindsay Mr. David J. Lionett Lions Club of Chicago Heights Mr. Jack L. Lipson Ms. Jennifer B. Lipson Ms. Julia Lissner Mr. Peter Litt Mr. Chester A. Lizak Ms. Nancy LoBue Lockport Fire Fighters Local 1544 Mr. & Mrs. John H. Loecke Mrs. Linda H. Loewenstein Mr. Anthony N. Logan Mr. Ernest Lohmar Ms. Mary Long Lora Lei Acres Homeowners Association Mr. Stanley R. Losinski Mr. Martin Low Mr. Stephen I. Lucas Ms. Danielle Luisi Mr. & Mrs. Mark Norman Lundgren Mr. John W. Lute Luther College Mr. Earl Lyden Mr. William R. Lyman Mr. & Mrs. Robert J. Machovec Jr. Ms. Heather J. Macklin 35 Madison Dearborn Partners, Inc. Mr. James Maggio Ms. Susan H. Maher Dr. Naznin A. Mahmood Ms. Ann Marie Malbeuf Mrs. Marci A. Malter Mr. & Mrs. David C. Manck Mr. James J. Mandarino Mr. & Mrs. Irwin B. Mandel Meredith Manni Ms. Barbara A. Manny Mr. & Mrs. Polyxeni Mantzakides Mr. & Mrs. Stephen P. Manus Mr. & Mrs. Nicola C. Manuzzi Mr. Kent A. Marburger Mr. & Mrs. Richard W. Marco Ms. Eve Marek Mr. Stephen P. Mares Ms. Mildred Margenau Mr. Daniel J. Marhigiani Ms. Sandra K. Marinucci Mr. Peter L. Markos Ms. Anna K. Marks Ms. Elizabeth Mars Mr. & Mrs. Daniel A. Marsh Mr. & Mrs. Thomas R. Marsh Mr. & Mrs. Alan Martin Mr. & Mrs. Jack W. Martin Ms. Laura Martin Dr. Lisa Anne Martin Ms. Mary C. Martindale Ms. Patricia Martindale Mr. & Mrs. Ronald A. Marwitz Mary Garrison Interiors Mr. & Mrs. Salvatore Massanisso Mr. & Mrs. James T. Massimilian Mr. & Mrs. Steven D. Masur Mrs. Evelyn Matasar Ms. Patricia Ann Mathis Mr. Nathan Z. Matisse Mr. John W. Matkey Mr. Zachary Matlin Ms. Beverly A. Matre Mr. & Mrs. Edward K. Matteson Ms. Suzanne Matthies Mr. & Mrs. Isaac Mayefsky Mrs. Terese O. Mayer Ms. Suzanne M. McArdle Mr. & Mrs. Thomas R. McBreen Ms. Christine A. McCabe Ms. Jacquelyn McCanse Mrs. Mary McCarthy Joan Q. McClellan Mr. Mark C. McCloy Ms. Pamela A. McCord Mrs. Tammy J. McCormick Mr. & Mrs. Adam M. McCostlin Ms. Virginia A. McDivit McDonald Hopkins LLC Ms. Elizabeth E. McDonald Mr. Robert U. McDowell Mr. Charles L. McElveen III Robin Josephs McGarvey & Patrick McGarvey Ms. Carol A. McGuff Mr. Thomas Clement McGuigan Mr. Eric G. McGuire Ms. Georgianna S. McGuire Mrs. Michelle M. McGuire Ms. Margaret S. McInerney Mrs. Nora Groh McKinley Mr. & Mrs. Martin J. McKinney Timothy McKula Ms. Rachel Monica McLaughlin Dr. Ronald W. McLawhon Ms. Janet F. McNair Ms. Marianne E. McNulty Mr. Don McQuilkin The McWethy Foundation Mecox Illinois, Inc. Mr. & Mrs. Marcus Meinzer Menalon Society Chapter 26 Ms. Eva Mergner Ms. Amy Merrick Ms. Meredith L. Manni Meserow Mr. & Mrs. Paul S. Messerschmidt Ms. Fleta F. Metcalf Ms. Judy A. Metcalf Mr. Philip L. Metcalf The Metron Group, Inc. Mr. Dale L. Meyer Mr. Eric Meyer Ms. Heather Meyer Ms. Jean F. Meyer Middlebury College Ms. Nicole M. Middleton Mr. & Mrs. Mark T. Mikita Ms. Catherine Miller Ms. Judy A. Miller Ms. Lana T. Miller Ms. Mary V. Miller Mr. & Mrs. Michael Miller Ms. Ashley Misenheimer Mr. & Mrs. Edward M. Miskell Sucheta Misra Dr. Bryan R. Mitchell* Mr. & Mrs. William T. Modrak Ms. Sara Moffitt UCCCC 2010-2011 Annual Report Mr. Syed Mohiuddin Mr. Michael M. Mollin Ms. Lavergne T. Moman Ms. Karen D. Monroe Ms. Roberta J. Monroe Ms. Sonya Monroe Mr. Richard Grunsten & Ms. Dehn Moon-Grunsten Ms. Megan Moore Ms. Janet C. Moran Ms. Mariah E. Moran Mr. & Mrs. Leo Morand Ms. Christine A. Mordach Ms. Jean E. Morfas Mr. Geyer Morford Mr. & Mrs. Michael C. Morgan Mr. James A. Morman Ms. Wilda W. Morris Ms. Niki J. Morrison Mr. Thomas E. Morrison Ms. Vivian Morton Mr. Kevin Mosley Mr. Sam’s Transportation, Inc. Mueller Funeral Homes Mr. Michael Mullen Ms. Margaret L. Mullin Mr. & Mrs. William E. Mullin Ms. Helen Mulopulos Multimedia Sales & Marketing Broadcast Services Mr. & Mrs. Timothy M. Mundt Mr. Thomas G. Murphy Ms. Jennifer Myerberg Mr. Frederick J. Nachman Dr. James Nachman* NASA/Wildcat Booster Club National Philanthropic Trust DAF Ms. Mackinzie Neal Mr. & Mrs. John D. Neef Mr. Richard Neely Mr. & Mrs. Stanley Neimark Mr. & Mrs. Gary M. Nejedly Mr. Andrew Nelson Mr. David D. Nelson Mr. Howard Nelson Ms. Jeannette A. Nelson Neo Kyma Messinias Mr. Brad H. Neuman Nevada Direct Insurance Company New Trier High School Boys Swimming/Diving Cary Newell Vicki Newell Diane B. Newman Mr. Gordon H. Newman Donations Support: New, one-of-akind program that focuses on the emerging field of cancer economics. * Deceased Donations Support: The acquisition of a cyclotron and development of a radiochemistry program that will help speed the advancement of personalized medicine. Mr. & Mrs. Melvin Newman Mr. Raymond T. Nice Mr. John R. Nickel Mr. William Nicolai Ms. Hanna Niewiarowski Mr. Richard S. Nikchevich Mr. Christopher Niro Thomas P. Noonan Ms. Susan L. North Mr. William L. North The Northern Trust Company Northwestern Il Bridge Association Ms. Carol Polk Norton Ms. Catherine Norton Mr. & Mrs. Timothy J. Notaro Mr. Jeffrey C. Novak Ms. Virginia S. Novak Ms. Carol Ann Novick Ms. Mary F. Novick Mr. & Mrs. Fred S. Novy Nutter, McClennen & Fish, LLP Mr. James E. Nyeholt Mr. & Mrs. John A. Oaks Ms. Laura O’Brien Ms. Marilyn J. O’Brien Mr. & Mrs. Daniel M. O’Brien Mr. Phillip O’Brien Mr. Roger O’Brien Ms. Ann Marie O’Connell Mr. William J. Donewald Ms. Cathie M. O’Donnell Ms. Nancy E. O’Donnell Mr. & Mrs. Cole Oehler Jr. Mr. & Mrs. William J. Ohlhaber Ms. Susan Okin Ole Henriksen of Denmark, Inc. Ms. Katelyn Olewinski Mr. Lawrence Olewinski Ms. Elizabeth Olson Omnivore Books on Food Mrs. Cathryn M. Onak Dr. Kenan & Dr. Karen Onel Ms. Nadia F. Ori Mr. James G. Orphan & Mrs. Irene A. Orphan Mr. Daniel J. O’Shea Ms. Tracy Oshita Mr. Raymond Osowski Mr. & Mrs. Terrence P. Ostrowski Overland Metals, LLC Mr. & Mrs. Stephen Paczolt Mr. & Mrs. Stephen B. Page Ms. Patricia E. Page S. Margaret Paik, MD Mr. & Mrs. Robert Palay 36 Mr. & Mrs. James Palilonis Mr. & Mrs. Jeffrey S. Palmer Ms. Marion T. Palumbo Ms. Kathy Panagakis-Laurisch Mr. Kevin Pang Mr. John M. Panicek Mr. James Papajohn Mr. & Mrs. Donald G. Papenburg Mr. & Mrs. Gust J. Pappas Ms. Eleftheria Pappas & Mr. Fotine Parzygnot Mr. & Mrs. Alberto Pappo Mr. Richard Park William B. Parker, MBA’78 Ms. Lena Parsons Ms. Robin Parsons Mr. & Mrs. Brian W. Patterson Ms. Janet Paulson Mr. Jeffrey Scott Pavlik Lucio Pavone Dr. & Mrs. Sachin Pawar Mr. Jack Payan PCNation Mr. & Mrs. Kirby Pearson Mr. J. Marshall Peck Ms. Lee Peck Mr. Robert E. Pence Mr. & Mrs. Kenneth L. Pendery Jr. Mrs. Kelley A. Pennington Pentair Residentail Filtration, LLC Mr. Ramon M. Perez Mr. & Mrs. Randall W. Perkins Ms. Bridget Perlmutter Ms. Patti A. Perlock Dr. & Mrs. Eduardo Perozo Terry L. Pesek Peter Snelten & Sons, Inc. Ms. Lily Peter Mr. Steve Peters Ms. Carol Petersen Ms. Lauren G. Peterson Ms. Missy Peterson Ms. Kristi Phelps Ms. Terry Philips Physicians Sports & Injury Center, Inc. Mr. & Mrs. Orren T. Pickell Ms. Hanna T. Piech Ms. Linda M. Pierce Mr. William S. Pilawski Mrs. Jennifer Pingle Mr. Daniel Pinkert Mr. Kirk Alan Pinkerton Pircher, Nichols & Meeks Mr. Gene E. Pitzer Mr. & Mrs. John J. Piva Jr. Plainfield Moose Family Center # 2491 Mr. & Mrs. Craig Planson Mr. & Mrs. Clarice S. Pleiter Mr. Paul Pokrifcak Ms. Barbara Polito Mr. & Mrs. William M. Pond Mr. Frank Ponterio Ms. Ruth M. Poparad Ms. Phyllis Popek Mr. Steven G. Poskanzer Mr. Eric Postpischil Mr. & Mrs. Angelos Potakis Ms. Barbara F. Potter Mr. & Mrs. Nicholas Poulopoulos Ms. Bess Poulos Mr. Dimitri J. Poulos Dr. John D. Poulos Mr. & Mrs. Sam Prassinos Dr. Irwin Press & Mrs. Andrea S. Press Ms. Victoria Pressling Mr. Gary Prestopino Kira Aberle Price Mr. Kyle Price Mr. Richard A. Price Mr. & Mrs. Greg Pritchard Mr. Scott Probst Ms. Pranitha V. Prodduturvar Ms. Catherine M. Prullage Mr. Stanton E. Puck & Ms. Claudia R. Belshaw Ms. Marie P. Queenan The Queenan Foundation Mr. John Quigley Ms. Kristin Quinn Ms. Doloris A. Radke Mr. & Mrs. Michael J. Rahn Mr. & Mrs. Walberto Ralon Ms. Yvonne Ralsky Mr. & Mrs. Gordon Ramig Mr. Joe L. Raudabaugh Ray Allen Inc. Raymond James Financial, Inc. Mr. Seth Noah Reagen Ms. Kelly Redmond Mr. & Mrs. Mark B. Reed Renee Rehkemper & Jeffrey Rehkemper Mr. Bradley Reiff Mr. & Mrs. Mark M. Reilly Mr. Gordon Reinhertz Reinhold & Lucille Groh Foundation Mr. Robert L. Reiser Mr. Carl Reiter Mr. Harvard Reiter Ms. Ann Rentschler Mr. Alexander Reo cancer.uchicago.edu Ms. Mary Jane Resendiz Mr. Mark Reshkin Restorative Dental Laboratory Mr. & Mrs. Demetri J. Retson Mr. & Mrs. Michael J. Revord Mary S. Reynolds Mr. Thomas F. Reynolds Ms. Ann Rezabek Mr. Samuel L. Rhone Mrs. Lynn D. Rice Dolores Richert, AM’66 Mr. & Mrs. David Riesmeyer Ms. Marilyn A. Riley Susan M. Riley The Risk Management Planning Group, Inc. Mrs. Burdette E. Ristenpart Mr. & Mrs. Milorod Ristich Dr. & Mrs. Ralph Robbins Roberts Salvage, Inc. Ms. Stacy Roberts Ms. Kimberly J. Robinson Mr. & Mrs. Francis Roche Mr. Thomas F. Rochford Mr. & Mrs. Stanley R. Rodgers Mr. Harold Rodin Astrid Rodriguez Mr. Donald L. Rogers Mr. Hector A. Rojas Dr. Brian B. Roman Mr. Michael Romano III Mr. Maya Romanoff Ronald Rubinstein Ltd. Mr. & Mrs. Frank Ronis Mr. Gerald L. Ronspies Harry B. & Francine Rosenberg Ms. Marlene Rosenberg Mr. & Mrs. Philip R. Rosenblatt Dr. Marsha Rosner & Dr. Robert Rosner Ms. Jean L. Ross Mr. & Mrs. Joel M. V. Roth Huron Consulting Group Dr. Clare K. Rothschild Mr. David Rothstein Mr. Seymour Rothstein Mr. & Mrs. Philip R. Rotner Mr. Gus M. Rousonelos Dr. & Mrs. Charles Rubin Mr. & Mrs. Frank R. Rubino Mr. Gerald J. Rudman Mrs. Howard Rudolf Mr. & Mrs. Richard S. Ruffolo Ms. Jennifer Rumbach Mr. & Mrs. John A. Rumbach Mr. & Mrs. Bob Rumbach Mr. Paul T. Rumbach Mr. & Mrs. Jack Rusher Mr. & Mrs. Gerald Russ Mr. Kemper Ryan Mr. William R. Rybak Ms. Joyce A. Ryburn Mr. Satish K. Sachdev Ms. Lisa Sagami Mrs. Loretta Salata Mr. Ron Salerno Mr. Andy Salk Mr. David L. Saloom Mr. & Mrs. Jerrold E. Salzman Mr. Sherley Sampson Mr. & Mrs. Thomas H. Sampson Mrs. Ellyn F. Samsky Ms. Marian J. Samstag Regina Sandberg Mr. Calvin Sanders Jr. Mrs. Marjorie Sandlow & Mr. Barry S. Rosen Mr. & Mrs. Mark Saran Ms. Judith E. Sarnat & Ms. Gail D. Zimmerman Ms. Janet K. Sarsh Ms. Bonnie J. Sartore Mr. James F. Sarwark Ms. Suzy Satterlee Mr. & Mrs. Jamie Saucedo Mr. & Mrs. James H. Saum Ms. Janelle M. Savage Ms. Judith Saville Ms. Sharon Sawallisch Mr. & Mrs. James W. Scanlon Mr. & Mrs. David J. Schachner Lawrence W. Schad Mr. & Mrs. Ingo Schaefer Ms. Kelly A. Schaefer Ms. P. J. Schaffer Mr. Robert P. Schaible Mr. & Mrs. Joel R. Schaider Mr. Sheldon Schak Ms. Alice K. Scheffler Mrs. Milton M. Scheffler Mrs. Carol Schempp Mr. & Mrs. Larry J. Schibilla Mr. & Mrs. Theodore J. Schiff Schiffer Publishing, Ltd. Mr. & Mrs. Adam R. Schimel Ms. Bayla Schimmel Ms. Sara Schimmel Mrs. Judy Schleisman Mr. & Mrs. Robert L. Schlossberg Mr. & Mrs. John R. Schmidt Mr. & Mrs. Frank Schmitz 37 Mr. & Mrs. Howard M. Schoenberger Mr. & Mrs. William Schoettler Ms. Anne Schreiner Mr. & Mrs. Richard A. Schuberth Mr. & Mrs. Steve Schuler Mr. Floyd A. Schultz Mr. Matthew Mason Schulz Mrs. Cathy Schulze Coll Mr. & Mrs. Robert L. Schum Mr. & Mrs. William Schuman Ms. Kathy Schwartz Mr. & Mrs. Michael R. Schwartz Ms. Orit Schwartz Mr .& Mrs. Richard D. Schwartz Ms. Linda Schwartzman Ms. Barbara A. Scieszka Mrs. Carol A. Scott Mr. Paul Scott Mr. & Mrs. Francesco Scozzaro Mr. E. Preston Scruggs II Ms. Christine M. Seber Mr. & Mrs. Stephen P. Seder Mr. & Mrs. Andy Sedlacek Mrs. Frances R. Seidman Mr. David R. Selmer Dr. Charlene Sennett Mr. Bernard Settler Seymour J. Bagan Trust Shagufta Shabbir Mr. & Mrs. Harold Shabelman Ms. Rupali Rajendra Shah Ms. Karen Shah-Mirany Mr. & Mrs. Alan Shalette Mr. Edwin Shangerg Lester & Edna Shapiro Family Foundation Sharpe Well Drilling Ms. Lillian R. Sharpe Mr. & Mrs. Neil J. Sheehan Sherman Media Company, Inc. Mr. Harry Sherman Mr. Lawrence A. Sherman Ms. Muriel Horn Sherman Mr. Young J. Shin Mr. & Mrs. Lloyd G. Shore Mr. Reuben Shore Mr. Norman Shubert & Mrs. Carol Shubert Mr. Frank L. Sibr Jr. Siegel Decorating Company Mr. Anthony J. Siegel Ms. Lauren Siegel Mrs. Elizabeth Sigler Ms. Jane Siklos Ms. Judy Sikora Mr. & Mrs. Jerry G. Silbert Silver, Lerner, Schwartz & Fertel Mrs. Elizabeth H. Silverman Mr. & Mrs. Gary Silverman Mr. Joseph V. Simeri Mr. Adam Simon Barbara & Michael Simon Ms. Nicole Simon Ms. Krishna Simonetti Mr. Terrico Simpson Ms. Leora Sims Mr. Richard Sinkuler Mr. & Mrs. Clive Sirkin Ms. Jean P. Skellchock Mr. & Mrs. Thomas John Skelly Mr. & Mrs. Gus P. Skizas Mr. & Mrs. Martin Skoglund Ms. Luanne Skow Ttee Karen Slimmon, MBA’91 & Andrew Slimmon, MBA’91 Ms. Wendi Elizabeth Sloane Ms. Anne R. Smith Ms. Emily K. Smith Mr. & Mrs. Gregory Smith Ms. Kristina Smith Mr. Melvin H. Smith Dr. Ralph H. Smith Jr. Mr. & Mrs. Robert K. Smith Mr. Ronald Smith Mr. A. W. Smithberger Mr. & Mrs. Edward J. Smosna Ms. Barbara Snidanko Ms. Donna Sobotka Gwen Solberg Mr. & Mrs. Gary Solomon Mr. & Mrs. Leonard H. Solomon Ms. Yekaterina L. Soloviov Mrs. Janie Song & Dr. David Song Mr. Chung Song Mr. Alan H. Sons Ms. Anne Sorock Mr. & Mrs. Vasilios T. Sotos Ms. Kiki Sotos Mr. & Mrs. Steve Sowski Speedway Auto Parts, Ltd. Mr. & Mrs. John S. Spegal Ms. Roslyn Spellman Mr. Earl L. Spencer Mr. & Mrs. Thomas Spitz Ms. Eileen Sprague Springfield Lakeshore Improvement Association St. Mary Immaculate Parish UCCCC 2010-2011 Annual Report Ms. Colleen Stachon Ms. Joan M. Stader The Stauber Family Foundation Ms. Barbara A. Stamper-Stevenson Standard Bearers Class Markle Church Ms. Marilynn Stanish Starks & Menchinger Family Funeral Home Ms. Kimberly G. Starman Ms. Cathy Stathakis Mr. & Mrs. William S. Stavros Mr. & Mrs. Harry Stavros Ms. Sarah Stefan Ms. Dolores Stefanisin Mr. & Mrs. Richard J. Stefanski Mr. & Mrs. David Eric Stein Mrs. Gail Stein Ms. Lisa G. Stein Mr. Ronald D. Stenger Mr. Allan J. Sternstein Ms. Nancy P. Stevens Ms. Gail Stewart Ms. Joanne T. Stewart Ms. Kim Stiffle Ms. Danielle Stone Mr. & Mrs. Joseph L. Stone Ms. L. Susan Stone Ms. Susan L. Stone Mr. & Mrs. Harold V. Stotland Mr. & Mrs. Peter C. Stott Mr. & Mrs. Edward J. Stransky Strategic Custom Builders Inc. Ms. Marilyn K. Straus Mr. Richard A. Strauss Mr. Edward D. Streicker Ms. Jennifer L. Stull Ms. Marsha L. Stull Mr. & Mrs. Mathew J. Stuve Mr. Scott Suckow Sullivan Family Fund Mr. Dennis M. Sullivan Ms. Linda Sullivan Ms. Lori T. Sullivan Ms. Mary P. Sullivan Mr. Thomas J. Sullivan Ms. Nancy Sulok Ms. Gabriela N. Sunga Susan & Marvin Dickman Family Charitable Trust Ms. Beverly Sussman Ms. Alessandra Vavas Swanson Ms. Gwen E. Swanson Peggy B. Swartchild Mrs. Olga Swiontek Ms. Elizabeth K. Szabo Donations Support: Research to identify genetic variants that will help determine which patients will respond best to certain cancer treatments. * Deceased Donations Support: Pediatric cancer research at UChicago’s Comer Children’s Hospital. Mr. & Mrs. Gregory George Tallas Mr. Bruce K. Tammen & Dr. Esther M. Menn Mr. Ted Tanaka Ms. Brenda Tarbell Ms. Anna Tasiopoulos Mr. Trevor Tay Team Penguins Mr. Edward Teel Jr. Ms. Michelle R. Teggelaar Mr. & Mrs. Earl H. Temkin Ms. Tracey Terese Terry Gebert Design Inc. Ms. Lenora Thinnes Mr. & Mrs. Robert W. Thomas Mr. William Thomas Michelle Thompson Mr. & Mrs. Ronald R. Thompson Thomson-West Mr. J. Randall Thrall Ms. Rhoda Thrall Ms. Lakisha Tidwell Ms. Linda Tidwell Mr. Donald H. Tieri Mr. & Mrs. Glenn R. Tilles Tix 4 Causes, LLC Ms. Dorothy A. Tobuch Mr. & Mrs. Steven Topel Mr. Manny Torres William Towle Mr. Mark Toyama Tranter Family Trust Ms. Traci L. Trapp Mr. Jesse Trevino Mr. & Mrs. Patrick Troy Truist Mr. Jerry Tscherrt Hunt Mr. Robert E. Tucker II Ms. Laura Tucker Mr. & Mrs. Anthony J. Turner Ms. Stacey L. Turner Ms. Eleni Tzotzolis Mr. Konstantinos Tzounos U.S. Bancorp Foundation The U.S. Charitable Gift Trust Mr. & Mrs. Timothy H. Ubben Dr. Mary T. Uckerman Mrs. Johanna R. Ugo-Conlon Mr. Pio D. Uliassi Union Bank of Switzerland United Way of Metropolitan Chicago Mr. David Ureel Ms. Patricia A. Vacilek Mr. & Mrs. Joseph M. Valerio Van Cleff & Arpels, Inc. Mr. Bernard Vance Mrs. Lorraine Vandenbergh Frances Vandervoort, CER’82, SB’57, SM’65 & Peter Vandervoort, AB’54, SB’55, SM’56, PHD’60 Ms. Marilyn K. Vanucci Mr. & Mrs. Nemesio P. Vargas Jr. Dr. Monica B. Vela Mr. & Mrs. Dennis C. Verenski Mr. Randolph K. Vest Mr. & Mrs. Robert Von Halle Mr. & Mrs. Kenneth Von Schnase Mr. Kenneth Von Schnase Ms. Karishma Vora Mr. Ralph D. Voris Mr. Matthew Vuckov Ms. Leslie J. Wadsworth Mr. & Mrs. Daniel Waechter Ms. Theresa M. Walczak Ms. Janet Waldman Mr. Harold Waldron Jr. Ms. Amy A. Walker Ms. Lorraine B. Walker Joseph Wallace Ms. Linda J. Wallace Mrs. Judith Wallis Ms. Judith A. Wallock Mr. Christopher Walsh Ms. Jennifer Walter Ms. Marcia Walz Mr. Edward Wanyandeh Mr. & Mrs. Wayne D. Warburton Mr. & Mrs. John Ward Mr. George Washington Ms. Margaret Y. Waterman Ms. Margaret Watson Ms. Karen Watson-Goddard Mr. & Mrs. Roland Wattman Mr. Howard Wax Mr. & Mrs. Harold Weaver Mr. & Mrs. Ralph Weaver Mr. & Mrs. Gregory M. Weber Mr. Seth Weinberger & Ms. Barbara Goodman Mr. & Mrs. Michael Weinger Mr. Samuel Weinstein Mr. Harvey A. Weiss Dr. Roy Emanuel Weiss & Ms. Fay Weiss Rabbi Victor H. Weissberg, DHL, DD Mr. Bill Weldon Ms. Linda Welton Mrs. Virginia R. Wendt Mr. & Mrs. Robert Werner Ms. Bernadette Westberg Mr. & Mrs. Mark Westcott Ms. Maureen E. Westhoff Westlake Motors LTD Mr. Sydney L. Weydemeyer Whalen Family Trust Mr. & Mrs. William White Mr. & Mrs. John A. Whittemore Mr. Edward E. Wicks & Mrs. Maralee Sabath Wicks Ms. Betsy Widdop Ms. Andrea E. Widen Mr. Robert Wiedeman Ms. Lindsay Wilde Mr. Daniel L. Williams Ms. Donna Jean Williams Mr. & Mrs. Scott Williams Mr. Herbert Williams Ms. La Ronnia D. Williams Ms. Rosetta Williams Mr. & Mrs. Jonathan F. Williams Mr. William J. Willis Ms. Margaret C. Wilson Mr. Harvey S. Wineberg Dr. & Mrs. Jerome A. Winer Mr. & Mrs. Ron Winkler Mr. Lynn G. Wodder & Ms. Eileen Wodder Mr. & Mrs. Jerrold Emil Wolf Mrs. Karel L. Wolfson Ms. Patricia A. Wolsfelt Mrs. Roycealee J. Wood Ms. Alma Woodward Mr. Chester Wright David Yeager, MBA’88 Ms. Eileen Yedlin Dr. & Mrs. Frederic D. Young Ms. Michelle Younghouse Mr. Z.R. Zaccone Sr. Mr. Mark Zancanaro Ms. Toni Zaro Ms. Katherine Zellmer Mr. Bruce M. Zessar Mr. Robert O. Zillmer Mr. Douglas H. Ziminski Mr. Karl R. Zimmer III Mr. & Mrs. William Zimmerman Mr. & Mrs. Jerrold R. Zisook Mr. & Mrs. Clifford J. Zosso Mr. Robert J. Zotti Mr. John Zownorega Ms. Alicia Zukowska Ms. Shelley E. Zuraw Mrs. Leon E. Zygmun * Deceased The UCCCC is enormously grateful for the generous, unwavering commitment of our contributors. Every effort was made to ensure the accuracy of this publication. Notification of errors or omissions should be made to: Marilyn Duran The University of Chicago Cancer Research Foundation 5841 S. Maryland Ave., MC1140, H212 Chicago, IL 60637-1470 38 Phone: 1-773-702-6566 Fax: 1-773-834-7855 [email protected] cancer.uchicago.edu 2010 – 2011 Financial Report At a challenging time for medical research philanthropy, the UCCRF has raised more than $2 million in the name of cancer research for the 6th consecutive year. We are pleased that while we have taken on additional third-party fundraising groups, we have controlled expenses. Beginning Balance Fiscal prudence has protected us from the economic downturn and permitted us to support over 30 major basic and clinical research projects again this year. $ 2,425,367 Income Income UCCRF Contributions $ 397,400 UCCRF Capital Campaign $ 479,976 Boards/Auxiliaries $ 1,196,299 Women’s Board Campaign $ 45,011 Endowment Income $ 81,111 Total Income $ 2,199,797 Boards/Auxiliaries 54.4% UCCRF Capital Campaign 21.8% UCCRF Contributions 18.1% Expenses Endowment Income 3.7% Operating* Personnel $ 308,222 Services $ 358,907 Supplies $ 5,103 $ 672,232 Woman’s Board Campaign 2.0% Expenses Allocations Research & Faculty Support $ 209,517 Women’s Board $ 540,000 Auxiliary Board $ 102,000 Associates Board $ 20,000 Capital Campaign $ 597,000 $ 1,468,517 Total Expenses /Allocations $ 2,140,749 Ending Balance $ 2,484,415 Allocations 68.6% Operating 31.4% * Period from 7/1/10 - 6/30/11 39 UCCCC 2010-2011 Annual Report A Look ahead We are very pleased to share with you our accomplishments of 2010-2011. We are even more excited about the promise for a future where many of cancer’s complexities will be unraveled to enable earlier, more precise diagnoses, more targeted treatments, and more comprehensive care for the increasing number of survivors and their families. Upholding the highest standards of excellence, innovation, and collaboration, the UCCCC will continue to undertake the bold initiatives that have led to many of the novel treatments that have become today’s standard of care. We envision a future where cancer is no longer a leading cause of death in many populations, but a set of illnesses that can be modified, managed, or even prevented. 40 cancer.uchicago.edu Help Make Today’s Science Tomorrow’s Standard of Care To make a donation or to learn more about how you can help our researchers explore new ways to diagnose and treat malignant disease, contact The University of Chicago Cancer Research Foundation (UCCRF) Executive Director Mary Ellen Connellan: Online: cancer.uchicago.edu/donations Phone: 1-773-834-7490 E-mail: [email protected] Mail: The University of Chicago Cancer Research Foundation 5841 S. Maryland Ave., MC1140, H212 Chicago, IL 60637 The UCCRF is a not-for-profit 501(c)(3) organization. Federation Tax Identification Number 36-6056201. All gifts are tax deductible as provided by law. The University of Chicago Comprehensive Cancer Center Follow us: Michelle M. Le Beau, PhD Director, UCCCC; Arthur and Marian Edelstein Professor of Medicine; Director, Cancer Cytogenetics Laboratory Today’s Science … Tomorrow’s Standard of Care Marcy A. List, PhD Associate Director for Administration, UCCCC; Scientific Director, Cancer Clinical Trials Office Marsha R. Rosner, PhD Deputy Director for Basic Sciences, UCCCC; Charles B. Huggins Professor and Chair, Ben May Department for Cancer Research Richard L. Schilsky, MD Deputy Director for Clinical Sciences, UCCCC; Professor of Medicine; Section Chief, Hematology/Oncology Habibul Ahsan, MBBS, MMedSc Associate Director for Population Research, UCCCC; Professor of Health Studies, Medicine, and Human Genetics Geoffrey L. Greene, PhD Associate Director for Basic Sciences and Education, UCCCC; Virginia and D.K. Ludwig Professor and Vice Chair, Ben May Department for Cancer Research; Co-Director, Ludwig Center for Metastasis Research Yves Lussier, MD* Associate Director for Biomedical Informatics, UCCCC; Associate Professor of Medicine; Director, Center for Biomedical Informatics Mark Ratain, MD Associate Director for Clinical Sciences, UCCCC; Leon O. Jacobson Professor of Medicine; Director, Center for Personalized Therapeutics Executive and Managing Editor: Natalie Boden (From left) UCCCC Associate Director Marcy List, PhD, Co-Deputy Director Marsha Rosner, PhD, Director Michelle Le Beau, PhD, and Co-Deputy Director Richard Schilsky, MD. Karen E. Kim, MD, MS Director, UCCCC Office of Community Engagement and Cancer Disparities; Associate Professor of Medicine Contributors: Mary Ellen Connellan, MA Jane Kollmer Cassie Simon, CTR Wendy Stock, MD James W. Vardiman, MD Design: Brierton Design Printer: G Thomas Partners James Schilling, PhD Associate Director for Core Facilities, UCCCC; Director, Office of Shared Research Facilities Natalie Olinger Boden Director, Communications and Public Relations Mary Ellen Connellan, MA Executive Director, The University of Chicago Cancer Research Foundation Rajan Gopalakrishnan, MS Director, Informatics Hoyee Leong, PhD Director for Scientific Communications and Strategic Partnerships Christine Miller, MA Director, Finance Consuelo Skosey, RN, CCRP Director, Clinical Research Operations; Technical Director, Cancer Clinical Trials Office * Dr. Lussier left UChicago in August 2011. © 2011 by The University of Chicago Comprehensive Cancer Center. All rights reserved. At t h e F o r e f ro n t o f D i s c ov e ry®