Light Therapy for Depression, and Other Treatment of Seasonal

Summary and Conclusions
Light Therapy for Depression,
and Other Treatment of
Seasonal Affective Disorder
A Systematic Review
Revision of Chapter 9 in SBU report
Treatment of Depression (2004), no 166/2
The Swedish Council on Technology Assessment in Health Care
SBU Board of Directors
and Scientific Advisory Committee
Secreteriat
måns rosén
:mZXji^kZ9^gZXidg!H7J
Board of Directors
nina rehnqvist
@Vgda^ch`V>chi^ijiZ
8]V^g
håkan billig
HlZY^h]GZhVgX]8djcX^a
håkan ceder
I]ZCVi^dcVa7dVgY
d[=ZVai]VcYLZa[VgZ
anna-karin eklund
HlZY^h]6hhdX^Vi^dc
d[=ZVia]Egd[Zhh^dcVah
anna engström-laurent
HlZY^h]HdX^Zind[BZY^X^cZ
ann hedberg balkå
I]ZHlZY^h]6hhdX^Vi^dc
d[AdXVa6ji]dg^i^ZhVcY
GZ\^dch
sven-olof karlsson
I]ZHlZY^h]6hhdX^Vi^dc
d[AdXVa6ji]dg^i^ZhVcY
GZ\^dch
eva nilsson bågenholm
I]ZHlZY^h]BZY^XVa
6hhdX^Vi^dc
håkan sörman
I]ZHlZY^h]6hhdX^Vi^dc
d[AdXVa6ji]dg^i^ZhVcY
GZ\^dch
gunnar ågren
I]ZHlZY^h]CVi^dcVa
>chi^ijiZd[EjWa^X=ZVai]
björn klinge
@Vgda^ch`V>chi^ijiZ
Scientific Advisory Committee
david bergqvist
JeehVaVJc^kZgh^in=dhe^iVa
8]V^g
mats eliasson
HjcYZgWn=dhe^iVa!AjaZ€
sölve elmståhl
Jc^kZgh^in=dhe^iVa!BVabŽ
anders anell
HX]ddad[:Xdcdb^XhVcY
BVcV\ZbZci!AjcYJc^kZgh^in mikael hellström
HV]a\gZch`V=dhe^iVa!
<ŽiZWdg\
björn beermann
BZY^XVaEgdYjXih6\ZcXn!
anders lindgren
JeehVaV
I]ZHlZY^h]B^c^hignd[
=ZVai]VcYHdX^Va6[[V^gh
cecilia björkelund
<ŽiZWdg\hJc^kZgh^in
kerstin nilsson
Jc^kZgh^in=dhe^iVa!ygZWgd
lisa ekselius
JeehVaVJc^kZgh^in
olof nyrén
@Vgda^ch`V>chi^ijiZ!
HdacV
jan palmblad
@Vgda^ch`V>chi^ijiZ!
=jYY^c\Z
björn sjöström
Jc^kZgh^ind[H`ŽkYZ
gunnevi sundelin
JbZ€Jc^kZgh^in
gunnel svensäter
BVabŽJc^kZgh^in
Summary and Conclusions of the SBU Report:
Light Therapy for Depression,
and Other Treatment of
Seasonal Affective Disorder
A Systematic Review
Revision of Chapter 9 in SBU report
Treatment of Depression (2004), no 166/2
December 2007
Project Group:
7Zc\i7gdghhdc
A^hV:`hZa^jh
>c\g^Y=€`VchdcEgd_ZXi6hh^hiVci
7_ŽgcB€giZchhdc
6\cZiVEZiiZghhdcEgd_ZXi9^gZXidg
Scientific Reviewers:
A^aIg~h`bVc"7ZcYo
<jccVg@jaa\gZc
English Translation:
@ZcHX]jWZgi
Report: Light Therapy for Depression, and Other Treatment of Seasonal Affective Disorder
/Þ«i\Ê-ÞÃÌi“>̈VÊ,iۈiÜÊUÊ- \ʙÇn‡™£‡nx{£Î‡£n‡nÊUÊ-- \Ê£{ä䇣{äÎÊ
,i«œÀÌʘœ\Ê£nÈÊUÊ*ÕLˆÃ…ˆ˜}ÊÞi>À\ÊÓääÇ
3
SBU’s Conclusions
Conclusions
‰ I]ZkVajZd[i]ZgVenl^i]Va^\]iWdm[dghZVhdcVaV[[ZXi^kZY^h"
dgYZgH69dghZVhdcVaYZegZhh^dcXVcWZcZ^i]ZgXdc[^gbZY
cdgY^hb^hhZY#I]jh!Vai]dj\]VcjbWZgd[hijY^Zh]VkZWZZc
ejWa^h]ZYh^cXZH7JgZaZVhZY^ih¹IgZVibZcid[9ZegZhh^dcº
gZedgi^c'%%)!i]Zi]ZgVenh]djaYhi^aaWZgZ\VgYZYVhZmeZg^"
bZciVa#I]ZgZ^hcdh^\c^[^XVciY^[[ZgZcXZWZilZZceaVXZWd
VcYa^\]ii]ZgVenl^i]gZ\VgYidi]ZcjbWZgd[eVi^Zcihl]d
^begdkZWnViaZVhi*%#I]ZgZhjaihVgZXdcigVY^Xidgnl]Zc
^iXdbZhidi]ZcjbWZgd[eVi^Zcihl]dZmeZg^ZcXZgZb^hh^dc#
H7J¼hbZiV"VcVanh^hd[hijY^Zhi]VijhZa^\]iWdmZhh]dlhi]Vi
i]Zi]ZgVengZYjXZhi]ZhZkZg^ind[YZegZhh^dcdcVgVi^c\hXVaZ
hdbZl]VibdgZi]VceaVXZWdYjg^c\i]Z[^ghi[ZllZZ`hWji
i]Vii]ZZ[[ZXi^hiZbedgVgn:k^YZcXZ<gVYZ/>chj[[^X^Zci
HX^Zci^[^X:k^YZcXZ#
‰ I]ZZk^YZcXZ^h^chj[[^X^ZciidYZiZgb^cZi]ZZ[[ZXid[a^\]i
i]ZgVen!l]Zi]ZgVhbdcdi]ZgVendgVhVcVY_jcXiidVci^"
YZegZhhVcih!dccdc"hZVhdcVaYZegZhh^dc#
‰ 6ai]dj\]igZVibZci^ca^\]ii]ZgVengddbh^hlZaaZhiVW"
a^h]ZY^cHlZYZc!cdhVi^h[VXidgn!XdcigdaaZYhijY^Zh]VkZ
WZZcejWa^h]ZYdci]ZhjW_ZXi#I]jh!i]ZgZ^hV\gZVicZZYid
XdcYjXihjX]hijY^Zhl^i]Zcdj\]eVgi^X^eVcihidYgVlgZa^VWaZ
XdcXajh^dch#6eegdm^bViZan&%%eVgi^X^eVcihVgZgZfj^gZYid
ZhiVWa^h]l]Zi]Zgi]Zi]ZgVen^hbdYZgViZanbdgZZ[[ZXi^kZ
i]VceaVXZWd#I]ZhijY^Zhh]djaYVahdiV`Z]ZVai]ZXdcdb^X
VheZXih^cidXdch^YZgVi^dc#
4
S B U S U M M A RY A N D C O N C LU S I O N S
Study quality and relevance refers to the scientific quality of a
particular study and its ability to reliably address a specific question.
Evidence Grade refers to the total scientific evidence for a conclusion,
ie, how many high-quality studies support it.
Evidence Grade 1 – Strong Scientific Evidence
A conclusion assigned Evidence Grade 1 is supported by a good systematic
literature overview with a meta-analysis or at least two studies with high
quality and relevance among the total scientific evidence. If some studies
are at variance with the conclusion, the Evidence Grade may be lower.
Evidence Grade 2 – Moderately Strong Scientific Evidence
A conclusion assigned Evidence Grade 2 is supported by a systematic
literature overview with a meta-analysis that fails to meet the requirements
for a good systematic overview in some respect or at least one study with
high quality and relevance and two studies with medium quality and relevance among the total scientific evidence. If some studies are at variance
with the conclusion, the Evidence Grade may be lower.
Evidence Grade 3 – Limited Scientific Evidence
A conclusion assigned Evidence Grade 3 is supported by a systematic
literature overview with a meta-analysis that fails to meet the requirements
for a good systematic overview in several respects or at least two studies
with medium quality and relevance among the total scientific evidence.
If some studies are at variance with the conclusion, the scientific evidence
may be regarded as insufficient or contradictory.
conclusions
conclusions
Fact Box 1 Study Quality and Relevance, Evidence Grade.
Insufficient Scientific Evidence
If no studies meet the quality and relevance criteria, the scientific
evidence is rated as insufficient to draw any conclusions.
Contradictory Scientific Evidence
If different studies are characterised by equal quality and relevance but
generate conflicting results, the scientific evidence is rated as contradictory and no conclusions are drawn.
FROM THE REPORT “LIG HT THER APY FOR DEPRESSION,
F R O M T H E R E P O R T “ M E T H O D S O F E A R LY P R E N ATA L D I A G N O S I S ”
A N D O T H E R T R E AT M E N T O F S E A S O N A L A F F E C T I V E D I S O R D E R ”
55
SBU’s Summary
Background
>c&.-)!9gCdgbVcGdhZci]Va!VehnX]^Vig^hiVcYCVi^dcVa>chi^"
ijiZd[BZciVa=ZVai]gZhZVgX]Zg![^ghiYZhXg^WZYVXdcY^i^dci]Vi
]ZXVaaZYhZVhdcVaV[[ZXi^kZY^hdgYZgH69dghZVhdcVaYZegZhh^dc#
H69^cXajYZYeZdeaZl]degZk^djhan]VYbV_dgYZegZhh^dcdg
W^edaVgY^hZVhZ!l]d]VYYZegZhh^kZZe^hdYZhYjg^c\ildXdchZX"
ji^kZVjijbchdgl^ciZgh!VcYl]dgZXdkZgZYYjg^c\i]ZWg^\]iZg
eVgid[i]ZnZVg#H69cdlgZ[ZghidhZVhdcVaYZegZhh^dcYjg^c\i]Z
heg^c\VcYhjbbZgVhlZaa#:e^YZb^dad\^XVahijY^Zhhj\\Zhii]Vi
&·&%d[i]ZedejaVi^dc!i]Z]^\]Zg[^\jgZhdXXjgg^c\^cCdgi]
6bZg^XV!^hV[[ZXiZY#=dlZkZg!bVcnd[i]ZhijY^Zh]VkZjhZYi]Z
HZVhdcVaEViiZgc6hhZhhbZciFjZhi^dccV^gZHE6FhZa["gVi^c\
hXVaZ!l]^X]iZcYhiddkZgZhi^bViZi]ZegZkVaZcXZd[i]ZY^hZVhZ
^ci]Zk^Zld[bdgZgZXZcigZhZVgX]&#
7ZXVjhZH69iZcYhidWZVhhdX^ViZYl^i]i]ZYVg`i^bZd[i]Z
nZVg!i]Z^YZVi]ViZmedhjgZida^\]iXdjaYVaaZk^ViZ^ihhnbeidbh
lVhegdedhZYZVgandc#BVcnhijY^Zh]VkZhjWhZfjZcianZmVb"
^cZYi]ZZ[[^XVXnd[i]ZgVenl^i]kVg^djhhdjgXZhVcY^ciZch^i^Zh
d[a^\]i!YjgVi^dchd[ZmedhjgZVcYi^bZhd[YVn#A^\]ii]ZgVen]Vh
VahdWZZcig^ZY[dgdi]ZgXdcY^i^dch!eVgi^XjaVganbV_dgYZegZhh^dc#
1
BV\cjhhdc6!EVgidcZcI#I]ZY^V\cdh^h!hnbidbVidad\n!VcYZe^YZb^dad\n
d[hZVhdcVaV[[ZXi^kZY^hdgYZg#8CHHeZXig'%%*0&%/+'*"()#
FROM THE R EPORT “ LIG HT THER APY FOR DEPR ESS ION ,
A N D O T H E R T R E AT M E N T O F S E A S O N A L A F F E C T I V E D I S O R D E R ”
7
H7JVhhZhhZYi]Za^iZgVijgZdca^\]ii]ZgVenVheVgid[V'%%)
gZedgiZci^iaZY¹IgZVibZcid[9ZegZhh^dcº ' #Dci]ZWVh^hd[
hijY^Zhi]Vi]VYWZZcejWa^h]ZYeg^dgidhjbbZg'%%(!i]ZgZedgi
XdcXajYZYi]Via^\]ii]ZgVenlVhcdbdgZZ[[ZXi^kZi]VceaVXZWd#
<^kZci]ViVcjbWZgd[cZlhijY^Zh]VkZWZZcejWa^h]ZYh^cXZ
i]Vii^bZ!i]dhZXdcXajh^dchcZZYZYgZk^Zl#BZVcl]^aZ!i]Z
HlZY^h]CVi^dcVa7dVgYd[=ZVai]VcYLZa[VgZ]VhgZfjZhiZYVc
jeYViZ^cXdccZXi^dcl^i]^ihZ[[dgiidaVnYdlccVi^dcVa\j^YZ"
a^cZh[dgVcm^ZinVcYYZegZhh^kZY^hdgYZgh#
H7JYZX^YZYideZg[dgbVhnhiZbVi^XgZk^Zld[i]Za^iZgVijgZ
dci]ZjhZd[a^\]ii]ZgVen[dgYZegZhh^dc#I]ZZ[[^XVXnd[di]Zg
bZi]dYh[dgigZVi^c\H69lVhVahdidWZVhhZhhZY#
I]ZgZk^ZllVh^ciZcYZYidVYYgZhhi]Z[daadl^c\fjZhi^dch/
™ >ha^\]ii]ZgVenbdgZZ[[ZXi^kZi]VceaVXZWd^cigZVi^c\H694
™ 6gZi]ZgZdi]ZgZ[[ZXi^kZYgj\i]ZgVe^Zh[dgH694
™ 9dZhi]ZZ[[ZXid[Vci^YZegZhhVcihdccdc"hZVhdcVaYZegZhh^dc
hZi^cbdgZgVe^Yanl]Zca^\]ii]ZgVen^hjhZYVhVcVY_jcXi
igZVibZci4
™ >ha^\]ii]ZgVenVbdgZZ[[ZXi^kZbdcdi]ZgVeni]VceaVXZWd
^cigZVi^c\cdc"hZVhdcVaYZegZhh^dc4
Methodology
I]ZEjWBZYYViVWVhZlVhhZVgX]ZY[dga^iZgVijgZ!VcYW^Wa^d"
\gVe]^Zh^cdkZgk^ZlhlZgZX]ZX`ZY#I]ZgZk^ZlXdkZgZYgVcYdb^hZY!
XdcigdaaZYig^Vahl^i]ViaZVhi&%eVgi^X^eVcih^cZVX]igZVibZci
\gdje#I]Za^\]ihdjgXZ]VYidZb^iWg^\]il]^iZa^\]i#HijY^Zh
i]VijhZYa^\]iVhVcVY_jcXiidlV`Zi]ZgVen!l]^X]^hcdiVYb^c"
^hiZgZY^cHlZYZc!lZgZZmXajYZY#I]ZdjiXdbZbZVhjgZ]VYid
2
H7J#IgZVibZcid[YZegZhh^dc#6hnhiZbVi^XgZk^Zl#hidX`]dab/I]ZHlZY^h]
8djcX^adcIZX]cdad\n6hhZhhbZci^c=ZVai]8VgZH7J0'%%)#H7JgZedgi
cd&++$'#
8
S B U S U M M A RY A N D C O N C LU S I O N S
WZhXdgZhdci]Z=Vb^aidc9ZegZhh^dcGVi^c\HXVaZ=9GHdg
HigjXijgZY>ciZgk^Zl<j^YZ[dgi]Z=Vb^aidc9ZegZhh^dcGVi^c\
HXVaZ·HZVhdcVa6[[ZXi^kZ9^hdgYZgKZgh^dcH><="H69#
I]Zegd_ZXi[daadlZYH7J¼hegdXZhh[dga^iZgVijgZgZk^Zlh#6aa
hijY^Zh^cXajYZYlZgZgZk^ZlZYWni]gZZ^cYZeZcYZcigZ[ZgZZh^c
i]Zegd_ZXi\gdjedci]ZWVh^hd[H7J¼hfjVa^iniZbeaViZ[dgehn"
X]^Vig^Xegd_ZXih#HijY^Zhi]VibZii]ZXg^iZg^V[dg]^\]dgbZY^jb
fjVa^inVcY^ciZgcVakVa^Y^inegdk^YZYi]ZhX^Zci^[^XWVh^h[dgYgV"
l^c\XdcXajh^dchVWdjiigZVibZciZ[[ZXih#I]ZXdcXajh^dchlZgZ
Vhh^\cZYZk^YZcXZ\gVYZh^cVXXdgYVcXZl^i]i]Z[VXiWdmVWdkZ#
I]Zegd_ZXiVahd^ckdakZYeZg[dgb^c\bZiV"VcVanhZhl]Zcedh"
h^WaZ^cdgYZgidVhhZhhi]ZbV\c^ijYZd[igZVibZciZ[[ZXih!VhlZaa
VhXdcYjXi^c\VhjgkZnd[Xa^c^XVaegVXi^XZ#
Results of the Literature Review
I]Z&-hijY^Zhi]VibZii]Z^cXajh^dcXg^iZg^V[dgbi]ZWVh^h
d[H7J¼hXdcXajh^dch#IldbZiV"VcVanhZhi]VilZgZeVgid[i]Z
gZk^Zlhj[[ZgZY[gdbhjX]hZg^djhbZi]dYdad\^XVa[aVlhi]Vi
i]ZnXdjaYcdiXdcig^WjiZidi]ZXdcXajh^dch#
Question 1:
Is light therapy more effective than placebo in treating SAD?
H^mhijY^Zhd[bZY^jbfjVa^inVcYgZaZkVcXZhZgkZYVhVWVh^h[dg
VYYgZhh^c\i]^hfjZhi^dc#I]ZZ[[^XVXnd[a^\]ii]ZgVenlVhY^["
[^XjaiidVhhZhh#6bZiV"VcVanh^heZg[dgbZYWni]Zegd_ZXi\gdje
h]dlZYi]Vi!bZVhjgZYVhi]ZY^[[ZgZcXZWZilZZcYZegZhh^dchXdgZh
WZ[dgZVcYV[iZgilddgi]gZZlZZ`hd[igZVibZci!a^\]ii]ZgVen
]VYVhbVaaWjih^\c^[^XVciVYkVciV\ZdkZgeaVXZWd#I]ZY^[[ZgZcXZ
hjWhZfjZcianY^hVeeZVgZY#>[i]ZdjiXdbZbZVhjgZlVhgZhedchZ
VgZYjXi^dcd[ViaZVhi*%dci]ZYZegZhh^dchXdgZ!i]ZgZlVh
cdY^[[ZgZcXZWZilZZci]Zild\gdjeh#I]ZbdhigZaZkVciXa^c^XVa
bZVhjgZ^hgZb^hh^dc^ckdak^c\V*%gZYjXi^dcdci]ZhXdgZXdb"
W^cZYl^i]VegZ"YZ[^cZYidehXdgZjedcXdbeaZi^dcd[igZVibZci#
FROM THE R EPORT “LIG HT THER APY FOR DEPR ESS ION ,
A N D O T H E R T R E AT M E N T O F S E A S O N A L A F F E C T I V E D I S O R D E R ”
9
BZVhjgZY^ciZgbhd[i]ZcjbWZgd[eVi^Zcihl]dZmeZg^ZcXZY[jaa
gZb^hh^dc!i]ZgZhjaihlZgZXdcigVY^Xidgn#
Question 2:
ÀiÊ̅iÀiʜ̅iÀÊivviV̈ÛiÊ­`ÀÕ}®Ê̅iÀ>«ˆiÃÊvœÀÊ-¶
;djghijY^Zhd[bZY^jbfjVa^inVcYgZaZkVcXZhZgkZYVhVWVh^h
[dgVYYgZhh^c\i]^hfjZhi^dc#Ildd[i]ZbXdbeVgZYhZaZXi^kZ
hZgdidc^cgZjeiV`Z^c]^W^idghHHG>hl^i]eaVXZWd!Wjii]ZZ[[ZXih
lZgZZfj^kdXVa#I]Zdi]ZgildhijY^ZhXdbeVgZYHHG>hl^i]a^\]i
i]ZgVenVcY[djcYi]Vii]ZnlZgZZfjVaanZ[[ZXi^kZ#<^kZci]Vii]Z
hijY^ZhaVX`ZYeaVXZWd\gdjeh!i]ZgZhjaihVgZY^[[^XjaiidVhhZhh
VcYcdXdcXajh^dchXVcWZYgVlc#
Question 3:
œiÃÊ̅iÊivviVÌʜvÊ>˜Ìˆ`i«ÀiÃÃ>˜ÌÃʜ˜Ê˜œ˜‡Ãi>ܘ>Ê`i«ÀiÃȜ˜ÊÃiÌʈ˜Ê
“œÀiÊÀ>«ˆ`ÞÊ܅i˜Êˆ}…ÌÊ̅iÀ>«ÞʈÃÊÕÃi`Ê>ÃÊ>˜Ê>`Õ˜VÌÊÌÀi>̓i˜Ì¶Ê
I]^hfjZhi^dcgZaViZhidV]nedi]Zh^hi]Via^\]ii]ZgVenXVcVaaZ"
k^ViZi]Zhnbeidbhd[YZegZhh^dcWZ[dgZi]ZZ[[ZXid[i]ZVci^"
YZegZhhVci]VhhZi^c#;djghijY^Zhd[bZY^jbfjVa^inVcYgZaZ"
kVcXZ!dcZd[l]^X]ZmVb^cZYi]Z^beVXid[Y^hXdci^cj^c\a^\]i
i]ZgVen!hZgkZYVhVWVh^h[dgVYYgZhh^c\i]^hfjZhi^dc#I]ZgZhjaih
lZgZ]^\]an]ZiZgd\ZcZdjh!VcYi]ZgZhjaihlZgZXdcigVY^Xidgn#
I]jh!cdXdcXajh^dchXVcWZYgVlcVWdjii]ZZ[[^XVXnd[a^\]i
i]ZgVenVhVcVY_jcXiigZVibZci#
Question 4:
Ãʏˆ}…ÌÊ̅iÀ>«ÞÊ>ʓœÀiÊivviV̈Ûiʓœ˜œÌ…iÀ>«ÞÊ
̅>˜Ê«>ViLœÊˆ˜ÊÌÀi>̈˜}ʘœ˜‡Ãi>ܘ>Ê`i«ÀiÃȜ˜¶
;^kZhijY^ZhlZgZ^YZci^[^ZY!WjidcanildlZgZd[bZY^jbfjVa^in
VcYgZaZkVcXZ#7ZXVjhZi]ZnZmVb^cZYi]ZZ[[ZXidcidiVaanY^["
[ZgZcieVi^ZciedejaVi^dchVcYi]ZgZhjaihlZgZXdcigVY^Xidgn!cd
XdcXajh^dchXVcWZYgVlc[gdbi]ZZk^YZcXZ#
10
S B U S U M M A RY A N D C O N C LU S I O N S
Overall Assessment
I]Za^iZgVijgZh]dlhi]Via^\]ii]ZgVen]VhViWZhiVhbVaaVcY
iZbedgVgnZ[[ZXidcH69!l]^aZi]ZZk^YZcXZi]Vi^igZa^ZkZhcdc"
hZVhdcVaYZegZhh^dc^h^chj[[^X^Zci#6aahijY^ZhjhZYa^\]iWdmZh!
cdgbVaanjhZY^ci]Z]dbZd[i]ZeVi^Zci#
I]ZgZhedchZhidVfjZhi^dccV^gZhZciidY^gZXidghd[ehnX]^Vig^X
jc^ih^cY^XViZYi]Via^\]ii]ZgVen^hlZaaZhiVWa^h]ZY^cHlZYZc#
7VhZYdci]ZbZi]dYYZkZadeZY^cHidX`]dabYjg^c\i]Z&..%h!
i]ZigZVibZci^cHlZYZc^hjhjVaanVYb^c^hiZgZY^cVa^\]ii]ZgVen
gddb#9jZidVaVX`d[hVi^h[VXidgnXdcigdaaZYig^Vahi]Vi]VkZhij"
Y^ZYi]ZZ[[^XVXnd[a^\]ii]ZgVengddbh!i]^higZVibZcih]djaY
hi^aaWZgZ\VgYZYVhZmeZg^bZciVa#
DcZVeegdeg^ViZgZhedchZidi]ZaVX`d[Zk^YZcXZldjaYWZ
idZVgbVg`gZhdjgXZh[dgi]Z]ZVai]XVgZegd[Zhh^dcidhijYni]Z
Z[[^XVXnd[a^\]ii]ZgVengddbhYjg^c\i]ZYVg`eVgid[i]ZnZVg#
6Xd"dgY^cViZYZ[[dgiidgZhdakZi]^h^hhjZVhfj^X`anVhedhh^WaZ
ldjaYWZVYk^hVWaZ#HjX]VhijYnh]djaYVahdiV`Z]ZVai]ZXd"
cdb^XVheZXih^cidXdch^YZgVi^dc#
I]VildjaY\^kZeVi^Zcihl^i]H69i]Zdeedgijc^inidX]ddhZ
WZilZZceVgi^X^eViZ^cVhX^Zci^[^XhijYnjh^c\a^\]ii]ZgVendgid
gZXZ^kZXjhidbVgnigZVibZci[dgYZegZhh^dc#6e^adihijYnjh^c\
Xd\c^i^kZWZ]Vk^djgVai]ZgVenh]dlZYVWZcZ[^X^Va!adc\"iZgb
Z[[ZXi!WjiVYY^i^dcVahijY^ZhVgZcZZYZYid^ckZhi^\ViZi]ZkVajZ
d[i]ZbZi]dY[dgH69#
FROM THE R EPORT “ LIG HT THER APY FOR DEPR ESS ION ,
A N D O T H E R T R E AT M E N T O F S E A S O N A L A F F E C T I V E D I S O R D E R ”
11
Reports
published by SBU
SBU Reports in English
DWhigjXi^kZHaZZe6ecdZVHncYgdbZ'%%,!cd&-)4
>ciZgkZci^dchidEgZkZciDWZh^in'%%*!cd&,(4
BdYZgViZan:aZkViZY7addYEgZhhjgZ'%%)!KdajbZ'!cd&,'$'
H^X`cZhh6WhZcXZ·8VjhZh!8dchZfjZcXZh!VcYE]nh^X^Vch¼H^X`cZhh8Zgi^[^XVi^dc
EgVXi^XZ!HXVcY^cVk^Vc?djgcVad[EjWa^X=ZVai]!hjeea+('%%)!&+,$hjeea
GVY^di]ZgVen[dg8VcXZg'%%(!KdajbZ'!cd&+'$'
IgZVi^c\VcYEgZkZci^c\DWZh^in'%%(!cd&+%4
IgZVi^c\6aXd]daVcY9gj\6WjhZ'%%(!cd&*+4
:k^YZcXZ7VhZYCjgh^c\/8Vg^c\[dgEZghdchl^i]HX]^ode]gZc^V&...$'%%&!cd)4
8]Zbdi]ZgVen[dg8VcXZg'%%&!KdajbZ'!cd&**$'
867<$EI86dgBZY^XVaI]ZgVen^c6c\^cVaEV^c&..-!cd&)&4
7dcZ9Zch^inBZVhjgZbZci!?djgcVad[>ciZgcVaBZY^X^cZ!KdajbZ')&Hjeea,(.
&..,!cd&',$hjeea
8g^i^XVa>hhjZh^cGVY^di]ZgVen&..+!cd&(%4
GVY^di]ZgVen[dg8VcXZg!KdajbZ&!6XiVDcXdad\^XV!Hjeea+&..+!cd&'.$&$hjeea
GVY^di]ZgVen[dg8VcXZg!KdajbZ'!6XiVDcXdad\^XV!Hjeea,&..+!cd&'.$'$hjeea
BVhhHXgZZc^c\[dgEgdhiViZ8VcXZg!>ciZgcVi^dcVa?djgcVad[8VcXZg!Hjeea.
&..+!cd&'+$hjeea
=nhiZgZXidbn·GVi^c\hd[6eegdeg^ViZcZhh###&..*!cd&'*4
BdYZgViZan:aZkViZY7addYEgZhhjgZ!?djgcVad[>ciZgcVaBZY^X^cZ!KdajbZ'(-
Hjeea,(,&..*!cd&'&$hjeea
867<VcYEI86#6A^iZgVijgZGZk^ZlVcYGVi^c\h###&..)!cd&'%4
A^iZgVijgZHZVgX]^c\VcY:k^YZcXZ>ciZgegZiVi^dc&..(!cd&&.4
Higd`Z&..'!cd&&+4
I]ZGdaZd[EI86&..'!cd&&*4
I]ZEgdWaZbd[7VX`EV^c·8dc[ZgZcXZGZedgi&.-.!cd&%,4
EgZdeZgVi^kZGdji^cZh&.-.!cd&%&4
SBU Summaries in English
A^\]iI]ZgVen[dg9ZegZhh^dc!VcYDi]ZgIgZVibZcid[HZVhdcVa6[[ZXi^kZ9^hdgYZg
'%%,!cd*&%"(,
BZi]dYhd[:VganEgZcViVa9^V\cdh^h'%%,!cd*&%"(9nheZeh^VVcY<Vhigd"dZhde]V\ZVaGZ[ajm'%%,!cd*&%"(+
DWhigjXi^kZHaZZe6ecdZVHncYgdbZ'%%,!cd*&%"(*
12
S B U S U M M A RY A N D C O N C LU S I O N S
7ZcZ[^ihVcYG^h`hd[;dgi^[n^c\;adjgl^i];da^X6X^YidGZYjXZi]ZG^h`d[CZjgVa
IjWZ9Z[ZXih'%%,!cd*&%"()
BZi]dYhd[Egdbdi^c\E]nh^XVa6Xi^k^in'%%,!cd*&%"((
B^aY=ZVY>c_jgn·>c"]dhe^iVaDWhZgkVi^dcdg8dbejiZYIdbd\gVe]n4
'%%,!cd*&%"('
BZi]dYhd[IgZVi^c\8]gdc^XEV^c'%%+!cd*&%"(&
BVadXXajh^dchVcYDgi]dYdci^XIgZVibZci^cV=ZVai]EZgheZXi^kZ'%%*!cd*&%"(%
EhnX]^Vig^XG^h`6hhZhhbZciBZi]dYh·6gZK^daZci6XihEgZY^XiVWaZ4
'%%*!cd*&%"'.
IgZVibZcid[6cm^Zin9^hdgYZgh'%%*!cd*&%"'>ciZgkZci^dchidEgZkZciDWZh^in'%%*!cd*&%"',
8]gdc^XEZg^dYdci^i^h·EgZkZci^dc!9^V\cdh^hVcYIgZVibZci'%%)!cd*&%"'+
BdYZgViZan:aZkViZY7addYEgZhhjgZ'%%)!cd*&%"'*
IgZVibZcid[9ZegZhh^dc'%%)!cd*&%"')
EgZhXg^WZYH^X`AZVkZ·8VjhZh!8dchZfjZcXZh!VcYEgVXi^XZh'%%)!cd*&%"'(
DhiZdedgdh^h·EgZkZci^dc!9^V\cdh^hVcYIgZVibZci'%%(!cd*&%"''
GVY^di]ZgVen[dg8VcXZg'%%(!cd*&%"'&
=ZVg^c\6^Yh[dg6Yjaih'%%(!cd*&%"'%
EgZkZci^dcd[9ZciVa8Vg^Zh'%%'!cd*&%"&.
EgZkZci^dc!9^V\cdh^hIgZVibZcid[KZcdjhI]gdbWdZbWda^hb'%%'!cd*&%"&DWZh^in·EgdWaZbhVcY>ciZgkZci^dch'%%'!cd*&%"&,
=dgbdcZGZeaVXZbZciI]ZgVen'%%'!cd*&%"&+
IgZVibZcid[6aXd]daVcY9gj\6WjhZ'%%&!cd*&%"&*
8]Zbdi]ZgVen[dg8VcXZg'%%&!cd*&%"&)
IgZVibZcid[6hi]bVVcY8DE9'%%%!cd*&%"&(
9nheZeh^V·BZi]dYhd[9^V\cdh^hVcYIgZVibZci'%%%!cd*&%"&'
7VX`EV^c!CZX`EV^c'%%%!cd*&%"&&
Jg^cVgn>cXdci^cZcXZ'%%%!cd*&%".
I]ZEVi^Zci·9dXidgGZaVi^dch]^e'%%%!cd*&%"Egd\cdhi^XBZi]dYh[dg6XjiZ8dgdcVgn6giZgn9^hZVhZ&...!cd*&%"&%
Hbd`^c\8ZhhVi^dcBZi]dYh&..-!cd*&%",
Gdji^cZJaigVhdjcY:mVb^cVi^dc9jg^c\EgZ\cVcXn&..-!cd*&%"+
Hjg\^XVaIgZVibZcid[G]ZjbVi^X9^hZVhZh&..-!cd*&%"'
EgZkZci^c\9^hZVhZl^i]6ci^dm^YVcih&..,!cd*&%")
8dbbjc^in>ciZgkZci^dc·8VgY^dkVhXjaVg9^hZVhZ&..,!cd*&%"(
I]ZJhZd[CZjgdaZei^Xh&..,!cd*&%"&
FROM THE R EPORT “ LIG HT THER APY FOR DEPR ESS ION ,
A N D O T H E R T R E AT M E N T O F S E A S O N A L A F F E C T I V E D I S O R D E R ”
13
SBU Alert Reports
:VganVhhZhhbZcid[cZl]ZVai]iZX]cdad\^Zh#;^cYi]ZbVilll#hWj#hZ$VaZgi
^cE9;[dgbVi#
To order SBU Reports?
I]ZgZVgZVahdhZkZgVagZedgih^cHlZY^h]#6aagZedgihXVcWZdgYZgZY
Villl#hWj#hZ!WnZ"bV^a^c[d5hWj#hZ!Wne]dcZ )+"-")&'('%%
dgWn[Vm )+"-")&&('+%#
14
S B U S U M M A RY A N D C O N C LU S I O N S
SBU Evaluates
Health Care Technology
7Zadl^hVWg^Z[hjbbVgnd[i]Zb^hh^dcVhh^\cZYidH7JWn
i]ZHlZY^h]<dkZgcbZci/
™ H7Jh]VaaVhhZhh]ZVai]XVgZbZi]dYhWnhnhiZbVi^XVaanVcY
Xg^i^XVaangZk^Zl^c\i]ZjcYZgan^c\hX^Zci^[^XZk^YZcXZ#
™ H7Jh]VaaVhhZhhcZlbZi]dYhVhlZaaVhi]dhZi]ViVgZVagZVYn
eVgid[ZhiVWa^h]ZYXa^c^XVaegVXi^XZ#
™ H7J¼hVhhZhhbZcihh]Vaa^cXajYZbZY^XVa!Zi]^XVa!hdX^VaVcY
ZXdcdb^XVheZXih!VhlZaaVhVYZhXg^ei^dcd[i]ZediZci^Va
^beVXid[Y^hhZb^cVi^c\i]ZVhhZhhZY]ZVai]iZX]cdad\^Zh
^cXa^c^XVaegVXi^XZ#
™ H7Jh]VaaXdbe^aZ!egZhZciVcYY^hhZb^cViZ^ihVhhZhhbZci
gZhjaihhjX]i]ViVaaeVgi^ZhXdcXZgcZY]VkZi]Zdeedgijc^in
idiV`ZeVgid[i]Zb#
™ H7Jh]VaaXdcYjXi^c[dgbVi^dcVaVcYZYjXVi^dcVaZ[[dgihid
egdbdiZi]ZVeea^XVi^dcd[^ihVhhZhhbZcihidi]ZgVi^dcVajhZd[
VkV^aVWaZgZhdjgXZh^cXa^c^XVaegVXi^XZ!^cXajY^c\YZciVaXVgZ#
™ H7Jh]VaaXdcig^WjiZidi]ZYZkZadebZcid[^ciZgcVi^dcVaXd"
deZgVi^dc^ci]Z[^ZaYd[]ZVai]iZX]cdad\nVhhZhhbZciVcYhZgkZ
VhVcVi^dcVa`cdlaZY\ZXZcigZ[dgi]ZVhhZhhbZcid[]ZVai]
iZX]cdad\^Zh#
Light Therapy for Depression,
and Other Treatment of
Seasonal Affective Disorder
I]ZH7JgZedgi^hWVhZYdcVhnhiZbVi^X
VcYXg^i^XVagZk^Zld[i]ZhX^Zci^ÄXa^iZgVijgZ#
>i^hdcZd[VhZg^Zhd[hX^Zci^ÄXgZedgihejW"
a^h]ZYWnH7JI]ZHlZY^h]8djcX^adc
IZX]cdad\n6hhZhhbZci^c=ZVai]8VgZ#
I]ZHjbbVgnVcY8dcXajh^dchd[i]Z
gZedgi!egZhZciZY^ci]^hWdd`aZi!]VkZWZZc
VeegdkZYWni]ZH7J7dVgYd[9^gZXidgh
VcYi]ZHX^Zci^[^X6Yk^hdgn8dbb^iiZZ#
H7J!7dm*+*%!B4"&&)-+HidX`]dab!HlZYZc™HigZZi6YYgZhh/Ing\ViVc,
IZaZe]dcZ/ )+"-")&'('%%™;Vm/ )+"-")&&('+%™lll#hWj#hZ™:"bV^a/^c[d5hWj#hZ